Miracle-dz/UniFAR-FTUs huggingface dataset:
Entrepreneurial orientation in the forestry industry: a population ecology perspective

Purpose – This study primarily seeks to focus on how entrepreneurial orientation (EO) may have influenced the evolution of SMEs in a constrained environment, namely the forestry industry. It also aims to find out how EO still acts on strategic intentions, management behaviour of the business leader and the SME's performance.Design/methodology/approach – The approach takes the form of an empirical study based on a sample of 717 forestry SME owner‐managers, with cluster analysis of the data, taking a population ecology perspective.Findings – The study reveals the existence of two types of forestry SMEs. The first, which could be referred to as an entrepreneurially‐oriented enterprise, generates a large portion of its revenues from out‐of‐forest activities. The second type is a small‐business‐oriented enterprise. In the context of the forestry sector, many opportunities to start a business were created following the decision of large corporations to subcontract their wood supply. The study shows how entrepre.
Unbroken Links? From Imperial Human Capital to Post-Communist Modernisation

Abstract The article explores imperial human capital affects on current human capital and democracy variations in Russia's regions based on author-constructed datasets with imperial and post-communist statistics. Pre-communist education is a significant predictor of modernisation, which in studies of Russian regions explains a large share of regional democratic variation. Pre-communist education also apparently positively affects post-communist democracy. The communists did not build on a clean slate; nor did they overwrite pre-communist human capital stocks in the regions. The spatially uneven structural conditions related to frontier settlement and population movements after the emancipation of the serfs may also have a bearing on human capital variations.
Introduction: the differentiated politicisation of European governance

Abstract The politicisation of European governance has become an important subject in debates about the institutional design, day-to-day decision-making and democratic legitimacy of the European Union. This special issue takes stock of this development of politicisation research, including the theoretical development as well as the rapidly expanding body of empirical evidence. It synergises the various perspectives on politicisation of European governance, building on a common understanding of politicisation as a three-dimensional process involving increasing salience, polarisation of opinion and the expansion of actors and audiences involved in EU issues. The introduction outlines the central theoretical and conceptual questions concerning the politicisation of European governance and provides a guiding framework for the contributions to this special issue. The contributions document that a differentiated Europe leads to differentiated politicisation across times, countries and settings. The differentiated patterns, particularly across countries, present profound challenges to the future trajectory of European integration and its democratic legitimacy.
Type 2 Endometrial Cancer is Associated With a High Density of Tumor-Associated Macrophages in the Stromal Compartment

Introduction: Tumor-associated macrophages (TAMs) play a pivotal role in orchestrating the microenvironment. The TAMs differentially polarize into M1 or M2 macrophages with distinct actions. The aim of our work is to characterize density, subtype, and location of TAMs in endometrial hyperplasia and cancer. Methods: Formalin-fixed, paraffin-embedded sections of hyperplasia (n = 5), type 1 (n = 5), and type 2 (n = 5) endometrial cancer were stained with anti-CD68 and anti-CD163 monoclonal antibodies as markers for total TAMs and M2 TAMs, respectively. Macrophages were counted at 40× magnification in 10 high-power fields (HPFs) per slide by 4 observers. Repeated measures models were constructed to determine the relationships between macrophages and lesion categories. Results: Most CD68+ TAMs were located in the stromal (mean = 41.0/HPF) compared to epithelial (mean = 11.0/HPF) or luminal (mean = 11.6/HPF) compartments. Similar but reduced findings were observed for CD163+ (M2 subtype) TAMs. The CD68+ stromal TAM density was highest in patients with type 2 cancers (mean = 54.0/HPF) compared to those with type 1 cancers (mean = 35.5/HPF) and hyperplasia (mean = 29.0/HPF). Women with hyperplasia had more CD163+ (M2 subtype) TAMs (26.7/HPF) than patients with either type of cancer (type 1 = 12.5/HPF and type 2 = 11.5/HPF). Based on the repeated measures models, type 2 cancers had 38.6/HPF more CD68+ TAMs than type 1 cancers (P < .0001) and type 1 and type 2 cancers had similar numbers of CD163+ TAMs (P = .27). Conclusions: Type 2 cancers have nearly twice the TAM density of type 1 cancers. This difference may be due to M1 macrophage predominance in the stroma of type 2 cancers.
Feed additive studies with newly weaned pigs: efficacy of supplemental copper, antibiotics and organic acids.

Six experiments involving 706 newly weaned 28- to 32-d-old pigs were conducted to evaluate the efficacy of copper (Cu) sulfate (to provide 250 mg/kg Cu), antibiotic-sulfa combinations [chlortetracycline, 110 mg/kg + penicillin, 55 mg/kg + sulfamethazine, 110 mg/kg; i.e., Aureo-Sulfa-Penicillin (ASP) or tylosin, 110 mg/kg + sulfamethazine, 110 mg/kg; i.e., Tylosin-Sulfa (TS)] and anhydrous citric or fumaric acid (.75 to 1.5% of the diet). The basal experimental diet was a 19% crude protein (CP)-fortified corn-soybean meal diet (1.08% lysine) containing 7% dried whey and 3% fish meal. Marked and consistent gain and gain/feed responses occurred from the Cu supplement, particularly during the first week postweaning. The antibiotic-sulfa combinations were less efficacious than Cu during the 1-wk postweaning stress period. During either the 1- or 3-wk growth periods, ASP and TS showed additivity with Cu in promoting rate and efficiency of weight gain. Liver Cu was increased by Cu addition to the diet, but neither ASP nor TS affected Cu deposition in the liver. In a factorial experiment involving 17% (1.01% lysine) or 20% CP (1.23% lysine) corn-soybean meal diets containing either no dried whey or an addition of 25% whey, Cu supplementation elicited marked improvements in rate and efficiency of weight gain, particularly in diets without added whey. Likewise, whey addition improved pig performance, especially when added to the diets containing no supplemental Cu. (ABSTRACT TRUNCATED AT 250 WORDS)
Epidermal Growth Factor and Ionizing Radiation Up-regulate the DNA Repair Genes XRCC1 and ERCC1 in DU145 and LNCaP Prostate Carcinoma through MAPK Signaling

Abstract Yacoub, A. , McKinstry, R. , Hinman, D. , Chung, T. , Dent, P. and Hagan, M. P. Epidermal Growth Factor and Ionizing Radiation Up-regulate the DNA Repair Genes XRCC1 and ERCC1 in DU145 and LNCaP Prostate Carcinoma through MAPK Signaling. Radiat. Res. 159, 439–452 (2003). This work examined the importance of radiation-induced and ligand-induced EGFR-ERK signaling for the regulation of DNA repair proteins XRCC1 and ERCC1 in prostate carcinoma cells, DU145 (TP53mut), displaying EGFR-TGFA-dependent autocrine growth and high MAPK (ERK1/2) activity, and LNCaP (TP53wt) cells expressing low constitutive levels of ERK1/2 activity. Using quantitative RT-PCR and Western analyses, we determined that ionizing radiation activated the DNA repair genes XRCC1 and ERCC1 in an ERK1/2-dependent fashion for each cell line. After irradiation, a rapid increase followed by a decrease in ERK1/2 activity preceded the increase in XRCC1/ERCC1 expression in DU145 cells, while only the rapid decrease in ERK1/2 preceded the increase in XRCC1/ERCC1 expression in LNCaP cells. Administration of EGF, however, markedly increased the up-regulation of phospho-ERK, ERCC1 and XRCC1 in both cell lines. Although the EGFR inhibitor tyrphostin (AG-1478) and the MEK inhibitor PD90859 both attenuated EGF-induced levels of the ERCC1 and XRCC1 protein, PD98059 blocked the induction of ERCC1 and XRCC1 by radiation more effectively in both cell lines. Inhibition of ERK at a level that reduced the up-regulation of DNA repair led to the persistence of apurinic/apyrimidinic (AP) sites of DNA damage and increased cell killing. Taken together, these data imply a complex control of DNA repair activation that may be more generally dependent on MAPK (ERK1/2) signaling than was previously noted. These data provide novel insights into the capacity of the EGFR-ERK signaling to modulate DNA repair in cancer cells and into the functional significance of this signaling.
Perceptions of the impact of depression and anxiety and the medication for these conditions on safety in the workplace

Background: The number of people taking prescribed medication for anxiety and depression has increased greatly, but little is known of how this medication impacts on safety at work. Aims: To examine the relation between anxiety and depression, prescribed medication, performance, and safety in the workplace. Methods: The research involved nine focus groups with sufferers of anxiety and depression to investigate experiences of mental health problems and the impact of psychotropic drugs. A further three focus groups were conducted with staff in human resources, personnel, occupational health, and health and safety departments, to explore organisational perspectives. The sample comprised 74 individuals drawn from a wide range of occupational sectors. Finally, the results were presented to a panel of experts from occupational medicine, general practice, psychology, health and safety, and psychiatry, to consider the implications for practice. Results: Workers reported that both the symptoms and the medication impaired work performance. Participants described accidents which they attributed to their condition or to the medication. Workers with responsibilities for others, such as teachers, healthcare workers, and managers appeared to present a particular safety risk. Healthcare workers believed that they placed themselves and their patients at risk when carrying out medical procedures. Conclusions: Respondents in this study felt that their symptoms of anxiety and depression and the medication they took to treat these conditions placed them at risk with respect to safety in the workplace. Drawing on the results, the authors outline areas for improvement in the management of mental health problems at work.
Gravity model by panel data approach: empirical evidence from Nigeria

Gravity trade model continues to be coveted for analysis of determinants of trade flows despite its lack of theoretical foundations. The main aim of the paper is to assess the determinants of the flow of Nigeria's exports using longitudinal data from 1999 to 2012. Extrapolating from the empirical literature, the paper constructs Nigeria's gravity trade model comprising nine EU countries, BRICS countries, Canada, Japan and the USA. Results from POOL and panel regressions - fixed and random effects show that market size and price index of destination countries positively drive trade flows in Nigeria, while relative factor endowment, economic similarities and geographical distance negatively affect Nigeria's trade flows. Furthermore, the paper found evidence in support of positive trade flows with the EU countries and negative trade flows with the BRICS countries and on account of cultural differences. Findings show that Nigeria's exports follow Linder hypothesis. These have important implications for economic, socio-cultural and bilateral trade negotiations for better trade performance in Nigeria in the future.
Hepatitis B and C virus infection in Romanian non‐Hodgkin's lymphoma patients

We determined the hepatitis C virus (HCV) antibodies (anti‐HCV) and the hepatitis B virus (HBV) surface antigen (HBsAg) in a cohort of 68 consecutive non‐Hodgkin's lymphoma (NHL) patients diagnosed and treated in our institution between December 1997 and March 1999. 27 cases were diagnosed as low‐grade, 33 as intermediate‐grade, and eight as high‐grade NHL. In 35 cases (51.4%) we found evidence of either HCV or HBV infection. Anti‐HCV antibodies were found in 20 patients (29.5%) and HBsAg was found in 21 patients (30.8%). In six patients both anti‐HCV and HBsAg were present. Anti‐HCV were present in 12/27 low‐grade NHL cases (44.4%) and in 8/41 intermediate/high‐grade (aggressive) NHL cases (19.5%, P < 0.03). HBsAg was found in 10/27 low‐grade NHL cases (37%) and in 11/41 aggressive NHL cases (26.8%). Evidence of liver disease, as reflected by elevated aminotransferases or typical alterations at liver biopsy, was present in eight patients. Cryoglobulins were present in six patients, all anti‐HCV positive and with low‐grade NHL. The prevalence of both HCV antibodies and HBsAg was significantly higher (P < 0.0001) in our NHL cases than in a sample of the general Romanian population, where the prevalence of anti‐HCV was 4.9% and that of HBsAg was 6.3%. It is difficult to say whether either HCV or HBV had actually been involved in lymphomagenesis or if α‐interferon treatment would be effective in this subset of patients.
Coyote Predation Control by Aversive Conditioning

Conditioned aversions were induced in coyotes by producing lithium chloride illness in them following a meal, and the effects upon eating and attack behavior were observed. One trial with a given meat and lithium is sufficient to establish a strong aversion which inhibits eating the flesh of that prey. One or two trials with a given flesh (lamb or rabbit) specifically suppresses the attack upon the averted prey but leaves the coyote free to attack the alternative prey. A method of saving both prey and predator is discussed.
Adipokine, adropin and endothelin-1 levels in intrauterine growth restricted neonates and their mothers

Abstract Intrauterine growth retardation/restriction (IUGR) is associated with fetal malnutrition. It has consequences for later life including increased incidence of obesity, diabetes mellitus, cardiovascular disease (CVD), and metabolic syndrome. Adipokines (adiponectin and leptin), adropin, and endothelin-1 are associated with obesity and metabolic syndrome regulation. Intrauterine changes in these mediators could affect programming of later adult obesity and metabolic syndrome. Our objectives were to compare the levels of these mediators in both cord and maternal blood between IUGR pregnancies and control, healthy pregnancies, and to study the correlation of adipokines with adropin and endothelin-1 in maternal and cord blood in IUGR pregnancies as well as in healthy control pregnancies. Maternal and cord blood samples were taken from 16 women with IUGR pregnancies and 16 women with healthy pregnancies. Serum levels of leptin, adiponectin, adropin, and endothelin-1 were measured by ELISA. Maternal blood adropin levels were significantly lower in the IUGR group than in the control group; the other mediators did not differ significantly. There was a positive correlation between maternal blood adropin and endothelin levels. (r=0.731, P=0.001) in the control but not the IUGR group. Cord blood adropin and adiponectin levels were significantly lower in the IUGR group compared with the control group, while leptin or endothelin-1 did not differ significantly. There was a negative correlation between adropin and leptin (r=–0.704, P=0.001) in the IUGR but not the control group cord blood. There were also positive correlations between endothelin and adropin for both groups (r=0.594, P=0.006; r=0.560, P=0.010, respectively); to the best of our knowledge, this is the first report of such a correlation. Differences in fetal expression of adropin and adiponectin in IUGR could influence programming of obesity, metabolic syndrome, diabetes, and CVD in later life.
Frames for the Future: Developing Continuing Education & Professional Development Programs for Spiritual Care Practitioners: A Perspective from Victoria, Australia

This article examines the educational issues in ongoing professional education for spiritual care practitioners. A meta-evaluation of registration and evaluation data over four years (between 2013 and 2016) of one such monthly program conducted by Spiritual Health Victoria (Australia) will be examined. Recommendations are made to support healthcare managers and spiritual care educators in designing and developing continuing education programs for spiritual care practitioners in a variety of other professional health and care contexts.
Psychometric properties of the Dresden Body Image Questionnaire: A multiple-group confirmatory factor analysis across sex and age in a Dutch non-clinical sample

Background Body image has implications for psychosocial functioning and quality of life and its disturbance is reported in a broad range of psychiatric disorders. In view of the lack of instruments in Dutch measuring body image as a broad concept, we set out to make an instrument available that reflects the multidimensional character of this construct by including more dimensions than physical appearance. The Dresden Körperbildfragebogen (DBIQ, Dresden Body Image Questionnaire) particularly served this purpose. The DBIQ consists of 35 items and five subscales: body acceptance, sexual fulfillment, physical contact, vitality, and self-aggrandizement. The main objective of the present study was to evaluate the psychometric properties of the Dutch translation of the Dresden Body Image Questionnaire (DBIQ-NL) in a non-clinical sample. Methods The psychometric properties of the DBIQ-NL were examined in a non-clinical sample of 988 respondents aged between 18 and 65. We investigated the subscales' internal consistency and test-retest reliability. In order to establish construct validity we evaluated the association with a related construct, body cathexis, and with indices of self-esteem and psychological wellbeing. The factor structure of the DBIQ-NL was examined via confirmatory factor analysis (CFA). The equivalence of the measurement model across sex and age was evaluated by multiplegroup confirmatory factor analyses. Results Confirmatory factor analyses showed a structure in accordance with the original scale, where model fit was improved significantly by moving one item to another subscale. Multiple group confirmatory factor analysis across sex and age demonstrated partial strong invariance. Internal consistency was good with little overlap between the subscales. Temporal reliability and construct validity were satisfactory. Conclusion Results indicate that the DBIQ-NL is a reliable and valid instrument for non-clinical subjects. This provides a sound basis for further investigation of the DBIQ-NL in a clinical sample.
A Determinantal Expression and a Recurrence Relation for the Euler Polynomials

In the paper, by a very simple approach, the author establishes an expression in terms of a lower Hessenberg determinant for the Euler polynomials. By the determinantal expression, the author finds a recurrence relation for the Euler polynomials. By the way, the author derives the corresponding expression and recurrence relation for the Euler numbers.
Comovements of Stock Markets in the CEE-3 Countries During the Global Financial Crisis

Abstract: This paper examines the comovements of stock markets in the CEE-3 (Central and Eastern European: Poland, the Czech Republic, and Hungary) countries using the VAR-GARCH-BEKK model over the period 2005–13. Research indicates that in the CEE-3 countries, volatility spillovers played a dominant role and that the stock exchanges in Poland, the Czech Republic, and Hungary did not react similarly to the global shocks of the recent crisis (2007–2013). We use a dynamic version of the Diebold–Yilmaz volatility spillover index to present the evolution of volatility transmission over time. The results show that the CEE-3 countries were volatility-takers in the period under analysis and that volatility spillovers were extremely high during periods characterized by market uncertainty.
Extreme Estimation Uncertainty in Fair Value Estimates: Implications for Audit Assurance

SUMMARY: The overall complexity and estimation uncertainty inherent in financial statements have increased in recent decades; however, the related reports and services have changed very little, including the format of the balance sheet and income statement, the content in the auditor's report, and the level and nature of assurance provided on estimates. We examine estimates reported by public companies and find that fair value and other estimates based on management's subjective models and inputs contain estimation uncertainty or imprecision that is many times greater than materiality. Importantly, changes in the estimates often impact net income; consequently, the extreme estimation uncertainty also resides in measures such as earnings per share. We do not question the value audits provide to the marketplace, the importance of fair value reporting, or the ability of auditors to deploy up-to-date valuation and auditing techniques. Rather, we suggest that the convergence of relatively recent events is plac.
Quantitative microvascular corrosion casting by 2D- and 3D-morphometry.

As a system of tubes (blood vessels) the cardiovascular system changes actively and passively diameters to adapt its transport capacities for respiratory gases, nutrients, heat, metabolites and waste products to and off the body's organs, tissues and cells. In most healthy organs blood vessels form a hierarchically arranged three-dimensional network with the geometry defined by vessel diameters, interbranching distances (defining branching frequencies and number of branching sites, i.e. nodes), intervascular distances, and branching angles. In the present study 2D- and 3D-morphometry is applied to quantify these parameters and their changes as they occur in resin casts during metamorphosis of the tadpole lung (2D-morphometry) and filter apparatus vasculature (3D-morphometry). It is shown that 2D-morphometry should be limited to the analysis of high powered images of flat two-dimensional vascular networks (example: tadpole lung alveolar vascular bed) to prevent underestimation of parameters. In contrast, 3D-morphometry can be applied over a wide range of magnifications whereby accuracy of measurements increases with the portion the structure to be measured occupies within the field of view. Together with a careful control of precasting conditions (application of vasoactive drugs, anaesthetics), casting conditions (pressure during rinsing and casting, amount of final shrinkage of casting media), and postcasting conditions (thermal burdening during maceration, sputtering, evaporation, and SEM inspection; thickness of conductive metal layers) 3D-morphometry enables to gain reliable data from resin casts of highly complex real vascular networks in healthy and diseased organs in the developing, juvenile, adult and aged state, as well as in different physiological states.