Miracle-dz/UniFAR-FTUs huggingface dataset:
Sex, Intimacy, and HIV

Abstract Combining elicitation interview, focus group discussion, and ethnographic observation data, we present an account of sociocul-tural and contextual influences on the emotionally and sexually intimate behavior of a self-defined social network of 11 heterosexually-active Puerto Rican men living in New York City, aged 18–29. Community influences included: (a) strong peer and familial ties, (b) distrust of outsiders, and (c) omnipresence of drugs, alcohol, and HIV/AIDS. Sexual script themes included: (a) pressure to fulfill culturally-defined male gender roles, (b) tensions between emotional versus sexual intimacy needs, (c) “good girl-bad girl” ambivalence, and (d) distrust of women. Safer sex themes included: (a) methods of assessing partner risk, (b) strategies for reducing HIV risk exposure, (c) ambivalence toward female-initiated condom use, and (d) feelings about pregnancy and fatherhood. Collectively, our findings highlight the need for developing community HIV prevention programs which utilize existing social structures to promote risk reduction, and address (a) traditional sexual scripts, norms, and values, (b) the interrelationship between drugs, alcohol, sex, and HIV/AIDS, and (c) men's competing desires for sexual versus emotional intimacy. Successful programs are likely to build upon traditional cultural and familial values and strengths, and seek to make men's natural sexual scripts safer rather than attempt to change deeply held and culturally-bound behavior.
Feasibility of Robot-Assisted Laparoscopic Surgery: An Evaluation of 35 Robot-Assisted Laparoscopic Cholecystectomies

Laparoscopic surgery offers patients distinct benefits but is not without its disadvantages to surgeons in terms of maneuverability and visualization. Robotic telemanipulation systems were introduced with the objective of providing a solution to the problems in this field of surgery. The feasibility of robot-assisted surgery was assessed by performing 35 laparoscopic cholecystectomies with the da Vinci robotic system. Time necessary for system setup and operation was recorded, as were complications, technical problems, postoperative hospital stay, morbidity, and mortality. Thirty-four of 35 cholecystectomy procedures were completed laparoscopically with the da Vinci system. Technical problems occurred in three cases, resulting in one intraoperative complication (a minilaparotomy caused by the loss of an instrument part). Median hospitalization was 2 days. There were no postoperative deaths or morbidity within 30 days after surgery. System setup time decreased as the experience of the operating team increased. Operating times were comparable with those reported for standard laparoscopic cholecystectomy. Robot-assisted surgery was repeatedly proven as a safe and feasible approach to laparoscopic cholecystectomy.
Endothelial Nitric Oxide Synthase T-786C Single Nucleotide Polymorphism: A Putative Genetic Marker Differentiating Small Versus Large Ruptured Intracranial Aneurysms

Background and Purpose— Anecdotal evidence exists for at least 2 subpopulations of intracranial saccular aneurysms, namely, those that may form rapidly and rupture when small versus those that enlarge slowly and may rupture particularly when ≥10 mm in diameter. We sought to determine whether the endothelial nitric oxide synthase (eNOS) T-786C single nucleotide polymorphism (SNP), implicated in cardiovascular disease susceptibility, could facilitate differentiation between small (≤5 mm) versus large (≥10 mm) ruptured aneurysms. Methods— In accordance with institutional guidelines, clinical data were recorded prospectively and genomic DNA was isolated from blood samples obtained from 52 aneurysmal subarachnoid hemorrhage (SAH) patients (cases) and 90 randomly selected controls. Samples were assayed for eNOS gene promoter T-786C SNP with the use of gene microarray technology. Statistical analyses included multiple logistic regression. Results— Although there was no difference in genotype distributions between cases and controls, all 13 patients with large aneurysms were (T/ C) heterozygous for the polymorphism, while 9 of 22 patients (41%) with small aneurysms were (T/ T or C/ C) homozygous (P =0.01). The mean (±SD) ruptured aneurysm diameter among all heterozygotes (8.5±5.2 mm) was significantly greater than that for C/ C (6.0±2.3 mm) or T/ T (4.7±1.8 mm) homozygotes (P =0.04). With the use of multivariate analysis, heterozygosity remained significantly associated with aneurysm size ≥10 mm (P =0.03). Conclusions— The eNOS T-786C SNP distinguishes genetically between small and large ruptured aneurysms. Although not predictive of SAH in the population at large, our data suggest that among persons with known intracranial aneurysms, eNOS T-786C genotype may be a factor influencing the size at which an aneurysm ruptures, a finding that should be taken into consideration along with other anatomic features of the aneurysm.
Genome-wide Identification of Chromosomal Regions of Increased Tumor Expression by Transcriptome Analysis 1

Genes up-regulated in tumor cells provide attractive anticancer therapeutic targets. Although the general underlying mechanism for the increased expression in tumors is unknown, tumor-specific up-regulation of some genes can be attributed to aberrant DNA amplification, a phenomenon common to many tumors. Using a computational method, we constructed a general transcriptome map with the human genomic sequences and expressed sequence tags in the public database. The transcriptome map revealed nonrandom chromosomal regions (termed region of increased tumor expression) where clusters of genes exhibited increased expression in the 10 tumor tissue types tested. These genomic regions often correspond to experimentally verified tumor amplicons. Our large-scale transcriptome analysis led to identification of many additional chromosomal regions with increased tumor expression, regions that represent potential tumor amplicons.
Perfil psicopatológico de niños con sobrepeso u obesidad en tratamiento de pérdida de peso

The aim of this study was to explore the psychopathological profile of overweight/obese children in treatment for weight loss in a specialized pediatric unit, in comparison with a group of non-overweight/obese children. A sample of 89 children (9 to 16 years-old) was evaluated for the presence of the following psychological variables: depression, anxiety, self-esteem and body satisfaction. The sample consisted of 44 overweight/obese children undergoing weight loss treatment and 45 normal-weight children. Compared to the children with normal weight, the overweight/ obese children presented more body dissatisfaction, lower academic and body self-esteem, and higher levels of anxiety. The variable which best discriminated between the groups was body dissatisfaction. The results support previous studies that have shown the presence of psychopathology in obese children, and the existence of differential psychopathological features.
Wait times from presentation to treatment for colorectal cancer: a population-based study.

BACKGROUND The wait time from cancer diagnosis to treatment has been a recent focus of cancer care in Canada. OBJECTIVE To examine the trends in wait times from patient presentation to treatment (overall health system wait time [OWT]) for colorectal cancer (CRC). METHODS Patients with colorectal adenocarcinomas, diagnosed between 2001 and 2005, and their first definitive treatments were identified from the population-based Manitoba Cancer Registry (Winnipeg, Manitoba). By linkage to Manitoba Health and Healthy Living's administrative databases, a patient's first gastrointestinal investigation (abdominal radiological imaging, lower gastrointestinal endoscopy or fecal occult blood test) before CRC diagnosis was identified. The index contact with the health care system was estimated from the date of the visit with the physician who ordered the first gastroenterological investigation. The OWT was defined as the time from the index contact to the first treatment, while diagnostic delay was defined as the time from the index contact to the diagnosis of CRC. Multivariate Cox regression analysis was performed to determine independent predictors of OWT. RESULTS The OWT was estimated for 2552 cases of CRC over the five years that were examined. The median OWT increased from 61 days in 2001 to 95 days in 2005 (P<0.001). Most of the increase was in diagnostic wait times (median of 44 days in 2001 versus 64 days in 2005 [P<0.001]). Year of diagnosis, older age, urban residence and diagnosis at a teaching facility were independent predictors of OWT. CONCLUSIONS The OWT from presentation to treatment of CRC in Manitoba steadily increased between 2001 and 2005, mostly due to diagnostic delays.
Allometric model for estimating leaf area in clonal varieties of coffee (Coffea canephora)

The evaluation of leaf area is required in several agronomic studies given their importance to assess the plant growth. The objective of this study was to use statistical models to estimate leaf area of five clonal varieties of coffee (Coffea canephora) from linear dimensions (length and width maximum). Were used in the studies five varieties of Coffea canephora Pierre ex Froehner: Emcapa 8111, Emcapa 8121 Emcapa 8131, Emcapa 8141 and at Incaper 8142. The results obtained in this study allow us to conclude that the linear model expresses the best estimate of leaf area. Among the different independent variables adopted, the product of length and greatest width (L.W) was found to be the greatest significance and higher coefficients of determination (R2). The regression equation that best expresses the estimated leaf area for the five clonal varieties is Ŷi = 0.6723 + 0.6779 xi, where xi represents the product of the greatest length and the greatest width of the leaves.
Bandwidth Enhancement Based on Optimized Via Location for Multiple Vias EBG Power/Ground Planes

The ground surface perturbation lattice (GSPL) structure is investigated to suppress power noise in the power distribution network of mixed signal circuits. In order to enhance the bandwidth of the noise suppression, the GSPL structure is implemented by using multiple vias in the mushroom-like electromagnetic bandgap structure. Under the concept of multiple vias, the lower and upper bound cutoff frequencies of the bandgap are influenced by the position of the vias. An optimum position for the vias is found to achieve maximum stopband bandwidth. In this paper, the stopband mechanism of GSPL structure is investigated and the corresponding equivalent circuit model is proposed to quickly predict the lower and upper bound cutoff frequencies. Suitable test boards are fabricated and measured to demonstrate the accuracy of the design concept. The result shows that there is a good consistency between simulated, modeled, and measured results.
Fruit and vegetable intake of schoolchildren in Quetzaltenango, Guatemala.

OBJECTIVE To determine if fruit and vegetable consumption among high- and low-socioeconomic status (HSES-LSES) urban schoolchildren in Quetzaltenango, Guatemala, was adequate according to World Health Organization (WHO) recommendations. METHODS Cross-sectional data from 449 third- and fourth-grade girls and boys from 12 elementary schools were collected, analyzed, and presented by socioeconomic status and gender. Public schoolchildren were classified as LSES (n = 219) and private schoolchildren were classified as HSES (n = 230). Dietary fruit/vegetable intake of each student was determined based on a 24-hour recall pictorial record and personal interview. All food items containing fruits or vegetables (including beverages) were classified and tabulated. Frequency of fruit/vegetable intake was calculated based on "mentions" (number of times a fruit or vegetable item was reportedly consumed), and nutritional adequacy was assessed for each group by mean and median values and compared to WHO daily recommended fruit/vegetable intake (400 g). Based on World Cancer Research Fund (WCRF) exclusion guidelines, the fruit/vegetable contribution to total energy was estimated. RESULTS Of the 247 different food items identified, 93 (37.7%) contained a fruit or vegetable. Total food mentions (n = 6 512) included 637 fruit items and 701 vegetable items. Although mean fruit/vegetable intake in grams was 461.3 (standard deviation, +/- 332.5), more than half (56.3%) of the subjects fell below the 400-g recommended daily level. Estimated fruit/vegetable contribution to total energy was 21.2% for HSES and 19.1% for LSES. CONCLUSION This study revealed inadequate fruit/vegetable intake among the study sample. For compliance with global recommendations, interventions promoting fruit/vegetable intake are needed.
Test-Retest Reliability of a Theory of Mind Task Battery for Children With Autism Spectrum Disorders

This study examined for the first time the test-retest reliability of theory-of-mind tasks when administered to children with Autism Spectrum Disorders (ASD). A total of 16 questions within 9 tasks targeting a range of content and complexity were administered at 2 times to 17 children with ASD. In all, 13 questions demonstrated adequate test-retest reliability and high internal consistency. Items that did not achieve reliability violated a pragmatic convention, were ambiguous, or were associated with a response bias. No effect of verbal ability or diagnosis was found on consistency of performance. There was no effect of interval (i.e., short vs. long) on change in score although modest increases in performance occurred generally across administrations. Implications for research and practice are considered.
Segmenting, Grouping and Tracking Vehicles in LIDAR Data

Brief Description of Research Project Roadway congestion impacts almost all aspects of our lives in the US, from safety, to the environment, to the quality of life, to the cost of goods and services. A comprehensive understanding of the traffic conditions over space that give rise to congestion remains elusive. To date, these issues have been studied predominantly with macroscopic data from point detectors (e.g., loop detectors) aggregated over fixed time periods ranging from 20 sec to 15 min. Many new theories have emerged in recent years to explain several on-going anomalies in traditional traffic flow theory. At the core of these new theories is the presence of non-trivial disturbances that last far less than the fixed time aggregation periods commonly used to study traffic, and thus, these micro-disturbances have not been empirically observed. If these theories are proven empirically, they should lead to better congestion management and control.
Prosecutor Selected Youth Diversion: Identifying the Circumstances and Conceptualizing the Cases

Crown selected youth diversion has received little academic attention in Canada. As a process that channels offenders out of the formal legal system, diversion purports to achieve contradictory self-serving system and offender-based goals. Using 50 randomly selected prosecution files – half of which the Crown diverted and half of which the Crown prosecuted – a mixed method investigation of diversion assesses cases through quantitative content analysis and grounded theory method. Based on the quantitative analysis, it is argued that there is an emerging patterned nature of Crown selected diversion that is not completely benign. This patterned nature of diversion unearths a distinctive discourse of diversion/nondiversion. Qualitatively, it is argued that the cases are organized around three temporal moments that create an area for distinctions to be made in terms of threat, responsibility, (in)tolerableness and recourse. Seemingly, there is a persistent paradoxical existence of the diversion process that emerges from the case files.
Acetaldehyde-Reinforcing Effects: A Study on Oral Self-Administration Behavior

Acetaldehyde (ACD) is the first metabolite of ethanol. Although, the role of ACD in ethanol addiction has been controversial, there are data showing a relationship. The objective of the current study was to further test the hypothesis that ACD itself is reinforcing. For this reason, we carried out a study on operant oral ACD self-administration. Wistar rats were trained to self-administer tap water or ACD by nose-poking in daily 30 min sessions for 15 consecutive days. Response on active nose-poke caused delivery of ACD solution or tap water, whereas responses on inactive nose-poke had no consequences. The results show that ACD maintains oral self-administration behavior and rates of active nose-pokes significantly higher than tap water. The dose–response plot for oral ACD self-administration is a “bell-shaped” curve suggesting reinforcing properties only in a limited range of doses. Furthermore, rats self-administering ACD show a deprivation effect upon ACD removal and gradually reinstated active nose-poke response when ACD was reintroduced. Overall, this study shows that ACD is orally self-administered and further supports the hypothesis that ACD possesses reinforcing properties, which suggests that some of the pharmacological effects attributed to ethanol may result from its biotransformation into ACD, thereby supporting an active involvement of ACD in ethanol addiction.
The Gendered Parenting of Political Leaders

Do we have different expectations of male and female politicians regarding parenting when young children are involved? If so, what are the implications for political citizenship? The aim of this article was to examine the construction of parenting and gender in the portrayal in Swedish print media of high-ranking politicians Gustav Fridolin, leader of the Green Party, and Birgitta Ohlsson, a Liberal Party member of the Swedish Government. The study covers reporting from 2010 up to the end of 2012. Methodologically, a discourse analysis based on discourse theory was performed, implying a textual analysis of 39 articles through gender theoretical lenses. Although fathers were seen as primary caregivers in some of the articles, a recurrent phenomenon was the repetition in Swedish newspaper articles of the idea that mothers rather than fathers should be considered primary caregivers. Furthermore, since Ohlsson was criticized for not choosing parental leave and the critical remarks about Fridolin were instead about him choosing parental leave, the different expectations on women as mothers and men as fathers in politics imply that even in a Nordic country context young children are a greater obstacle for female rather than for male politicians. Thus, gender inequalities between women's and men's political citizenship continue to persist in Sweden.
N 2,N 2,N 6,N 6-Tetrakis(2,3,4,5,6-pentafluorobenzoyl)pyridine-2,6-diamine

The title compound, C33H3F20N3O4, is a highly fluorinated organic imide that was isolated as an unexpected product from the reaction of 2,6-diaminopyridine with 2,3,4,5,6-pentafluorobenzoyl chloride in a 1:2 molar ratio. The molecule is located on a twofold axis and one of its symmetry-independent 2,3,4,5,6-pentafluorobenzoyl groups is disordered over two sets of sites, the occupancy of the major component being 0.773 (3). In the major component, the dihedral angle between the perfluorophenyl groups is 63.64 (10)°, and these groups form dihedral angles of 67.14 (7) and 21.1 (2)° with the pyridine core. Short intermolecular C—H⋯O and C—H⋯N contacts are found in the crystal structure.
Randomized, phase II, placebo-controlled, double-blind study with and without enzastaurin in combination with paclitaxel and carboplatin as first-line treatment followed by maintenance treatment in advanced ovarian cancer.

PURPOSE Enzastaurin is an oral serine/threonine kinase inhibitor antitumor agent. Our phase II trial tested the efficacy and safety of enzastaurin added to a standard carboplatin/paclitaxel chemotherapy regimen in patients with newly diagnosed advanced ovarian cancer. PATIENTS AND METHODS This was a randomized, placebo-controlled study in patients with International Federation of Gynecology and Obstetrics stage IIB to IV ovarian, fallopian tube, or peritoneal epithelial carcinoma. Patients were randomly assigned to six cycles of chemotherapy (paclitaxel/carboplatin ± enzastaurin [PCE/PC]) followed by maintenance therapy (enzastaurin/placebo). Primary end point was progression-free survival (PFS). Secondary measures included response rate, safety assessment, and translational research. RESULTS A total of 142 patients were randomly assigned to PCE (n = 69) or PC (n = 73). Patients in the PCE group had a 3.7-month longer median PFS compared with patients in the PC group; this was not statistically significant (hazard ratio [HR], 0.80; 95% CI, 0.50 to 1.29; P = .37). Safety profiles of the treatment arms were comparable. Frequency of discontinuation because of adverse events was similar (PCE, 11.9%; PC, 9.7%). Multivariate analyses confirmed the importance of optimal debulking with regard to PFS (debulking optimal v suboptimal: HR, 0.51; 95% CI, 0.30 to 0.85; P = .009). HR for covariate stage (stage IIB to IIIB v IIIC to IV) was not statistically significant (0.75; 95% CI, 0.38 to 1.47; P = .40). Translational research of immunohistochemistry protein assays did not identify any markers significantly associated with treatment difference regarding PFS. CONCLUSION The PCE combination increased PFS, but it was not significantly superior to PC in this phase II study.
Behaviour, crime, and legal processes : a guide for forensic practitioners

BEHAVIOURAL SCIENCES AND LEGAL PROCESSES. Behavioural Sciences Applied to Forensic and Legal Contexts (J. McGuire, et al.). The Legal Context: Obstacle or Opportunity? (D. Carson). Psychology and Police Investigation (P. Ainsworth). Factors Influencing Witness Evidence (A. Memon & D. Wright). Psycho-legal Studies as an Interface Discipline (N. Eastman). Decision-Making in Legal Settings (J. McEwan). RESEARCH AND PRACTICE. Explanations of Offence Behaviour (J. McGuire). Psychosis and Offending (A. O'Kane & R. Bentall). Risk Assessment and Prediction (R. Blackburn). Systems of Services (D. Heywood). Care and Management in the Community (T. Mason). Treatment of Sexual Deviation and Aggression (J. Hird). Treatment Approaches with Mentally Disordered Offenders (A. Grounds). Effective Interventions, Service and Policy Implications (J. McGuire, et al.). Index.
Plasma thrombomodulin levels in children with atopic dermatitis

Plasma thrombomodulin (TM) levels were measured in 68 patients with atopic dermatitis (AD) and 35 controls. Plasma TM levels in patients with AD were significantly higher than those of controls (p < 0.01). A significant correlation was observed between plasma TM levels and skin scores of AD or peripheral eosinophil counts (p < 0.01). There was also a positive correlation between plasma TM and vascular cell adhesion molecule‐1 levels (p < 0.05).