Miracle-dz/UniFAR-FTUs huggingface dataset:
Patterning Muscles Using Organizers: Larval Muscle Templates and Adult Myoblasts Actively Interact to Pattern the Dorsal Longitudinal Flight Muscles of Drosophila

Pattern formation in muscle development is often mediated by special cells called muscle organizers. During metamorphosis in Drosophila, a set of larval muscles function as organizers and provide scaffolding for the development of the dorsal longitudinal flight muscles. These organizers undergo defined morphological changes and dramatically split into templates as adult fibers differentiate during pupation. We have investigated the cellular mechanisms involved in the use of larval fibers as templates. Using molecular markers that label myoblasts and the larval muscles themselves, we show that splitting of the larval muscles is concomitant with invasion by imaginal myoblasts and the onset of differentiation. We show that the Erect wing protein, an early marker of muscle differentiation, is not only expressed in myoblasts just before and after fusion, but also in remnant larval nuclei during muscle differentiation. We also show that interaction between imaginal myoblasts and larval muscles is necessary for transformation of the larval fibers. In the absence of imaginal myoblasts, the earliest steps in metamorphosis, such as the escape of larval muscles from histolysis and changes in their innervation, are normal. However, subsequent events, such as the splitting of these muscles, fail to progress. Finally, we show that in a mutant combination, null for Erect wing function in the mesoderm, the splitting of the larval muscles is aborted. These studies provide a genetic and molecular handle for the understanding of mechanisms underlying the use of muscle organizers in muscle patterning. Since the use of such organizers is a common theme in myogenesis in several organisms, it is likely that many of the processes that we describe are conserved.
Affective Incoherence Reduces Reliance on Activated Stereotypes

The present research asked if experiences of affective coherence and incoherence regulate tendencies to respond based on activated stereotypes. Affective coherence occurs when affective feelings and activated affective concepts are in harmony, and affective incoherence occurs when such feelings and concepts are in conflict. This experiment shows that when the valence of accessible thoughts and participants' mood were affectively coherent, this promoted tendencies to respond based on activated stereotypes. When the valence of accessible thoughts and participants' mood were affectively incoherent, this inhibited tendencies to respond based on activated stereotypes. Further, results indicated that the influence of affective coherence and incoherence on stereotyping was driven by variation in feelings of positive affect. These results extend past research on affective coherence and incoherence by showing that such experiences not only influence the acquisition and organization of knowledge, but also the relia.
Long recovery VLF perturbations associated with lightning discharges

[1] Long D-region ionospheric recovery perturbations are a recently discovered and poorly understood subcategory of early VLF events, distinguished by exceptionally long ionospheric recovery times of up to 20 min (compared to more typical ∼1 min recovery times). Characteristics and occurrence rates of long ionospheric recovery events on the NWC transmitter signal recorded at Malaysia are presented. 48 long recovery events were observed. The location of the causative lightning discharge for each event is determined from GLD360 and WWLLN data, and each discharge is categorized as being over land or sea. Results provide strong evidence that long recovery events are attributed predominately to lightning discharges occurring over the sea, despite the fact that lightning activity in the region is more prevalent over land. Of the 48 long recovery events, 42 were attributed to lightning activity over water. Analysis of the causative lightning of long recovery events in comparison to all early VLF events reveals that these long recovery events are detectable for lighting discharges at larger distances from the signal path, indicating a different scattering pattern for long recovery events.
Public Street Lights Increase House Infestation by the Chagas Disease Vector Triatoma dimidiata

Triatoma dimidiata is one of the primary vectors of Chagas disease. We previously documented the spatio-temporal infestation of houses by this species in the Yucatan peninsula, Mexico, and found that non-domiciliated triatomines were specifically attracted to houses. However, the factors mediating this attraction remained unclear. Artificial light has been known for a long time to attract many insect species, and therefore may contribute to the spread of different vector-borne diseases. Also, based on the collection of different species of triatomines with light traps, several authors have suggested that light might attract triatomines to houses, but the role of artificial light in house infestation has never been clearly demonstrated and quantified. Here we performed a spatial analysis of house infestation pattern by T. dimidiata in relation to the distribution of artificial light sources in three different villages from the Yucatan peninsula, Mexico. In all three villages, infested houses were significantly closer to public street light sources than non-infested houses (18.0±0.6 vs 22.6±0.4 m), and street lights rather than domestic lights were associated with house infestation. Accordingly, houses closer to a public street lights were 1.64 times more likely to be infested than houses further away (OR, CI95% 1.23–2.18). Behavioral experiments using a dual-choice chamber further confirmed that adult male and females were attracted to white light during their nocturnal activity. Attraction was also dependent on light color and decreased with increasing wavelength. While public lighting is usually associated with increased development, these data clearly show that it also directly contributes to house infestation by non-domiciliated T. dimidiata.
Global inverse modeling of CH4 sources and sinks: An overview of methods

Abstract. The aim of this paper is to present an overview of inverse modeling methods that have been developed over the years for estimating the global sources and sinks of CH4. It provides insight into how techniques and estimates have evolved over time and what the remaining shortcomings are. As such, it serves a didactical purpose of introducing apprentices to the field, but it also takes stock of developments so far and reflects on promising new directions. The main focus is on methodological aspects that are particularly relevant for CH4, such as its atmospheric oxidation, the use of methane isotopologues, and specific challenges in atmospheric transport modeling of CH4. The use of satellite retrievals receives special attention as it is an active field of methodological development, with special requirements on the sampling of the model and the treatment of data uncertainty. Regional scale flux estimation and attribution is still a grand challenge, which calls for new methods capable of combining information from multiple data streams of different measured parameters. A process model representation of sources and sinks in atmospheric transport inversion schemes allows the integrated use of such data. These new developments are needed not only to improve our understanding of the main processes driving the observed global trend but also to support international efforts to reduce greenhouse gas emissions.
The effects of tongue pressure strength and accuracy training on tongue pressure strength, swallowing function, and quality of life in subacute stroke patients with dysphagia: a preliminary randomized clinical trial

Tongue pressure strength and accuracy training (TPSAT) has been proposed as an intervention to improve dysphagia. However, the effects of TPSAT on dysphagia in subacute stroke patients remain unclear. The aim of this study was to investigate the effects of TPSAT on tongue pressure strength, swallowing function, and quality of life in subacute stroke patients with dysphagia. Sixteen subacute stroke patients were assigned randomly to two groups: the TPSAT group (n=8) or the control group (n=8). In the former, both TPSAT and traditional dysphagia therapies were performed for 30 min each per day; in the latter, only traditional dysphagia therapy was performed for 30 min twice a day. Both groups performed each daily intervention five times per week for 8 weeks. To assess the tongue pressure strength, maximum isometric tongue pressures (MIPs) of the anterior and posterior tongue using the Iowa Oral Performance Instrument were measured before and after the intervention. Mann Assessment of Swallowing Ability (MASA) and Swallowing-Quality of Life (SWAL-QOL) were also used to assess the swallowing function and quality of life, respectively. TPSAT with traditional dysphagia therapy significantly improved MASA, SWAL-QOL, and MIPs both anteriorly and posteriorly, and traditional dysphagia therapy significantly increased MASA, SWAL-QOL, and MIPs anteriorly (P<0.05). The TPSAT group showed a significant improvement in anterior and posterior MIPs and tongue movement score in MASA compared with the control group (P<0.05). Our findings suggest that TPSAT may significantly improve dysphagia management in subacute stroke patients.
Concentration and moderate deviations for Poisson polytopes and polyhedra

The convex hull generated by the restriction to the unit ball of a stationary Poisson point process in the $d$-dimensional Euclidean space is considered. By establishing sharp bounds on cumulants, exponential estimates for large deviation probabilities are derived and the relative error in the central limit theorem on a logarithmic scale is investigated for a large class of key geometric characteristics. This includes the number of lower-dimensional faces and the intrinsic volumes of the random polytopes. Furthermore, moderate deviation principles for the spatial empirical measures induced by these functionals are also established using the method of cumulants. The results are applied to deduce, by duality, fine probabilistic estimates and moderate deviation principles for combinatorial parameters of a class of zero cells associated with Poisson hyperplane mosaics. As a special case this comprises the typical Poisson-Voronoi cell conditioned on having large inradius.
PaV1 infection in the Florida spiny lobster (Panulirus argus) fishery and its effects on trap function and disease transmission

The Caribbean spiny lobster (Panulirus argus) supports the most economically valuable fishery in the Caribbean. In Florida, USA, the majority of the catch is landed in traps "baited" with live, sublegal-sized lobsters that attract other lob- sters due to their social nature. This species is also commonly infected by the pathogenic virus Panulirus argus Virus 1 (PaV1). Here we describe a polymerase chain reaction (PCR) based assessment of the prevalence of PaV1 in the lobster fishery from the Florida Keys. We tested the effect of PaV1-infected lobsters in traps on catch and on transmission to other trapped, uninfected lobsters. We found that 11% of the lobsters caught in commercial traps were positive for the virus by PCR, but none of these animals showed visible signs of disease. We also tested whether healthy lobsters avoid diseased lob- sters in traps. Traps into which we introduced an infected lobster caught significantly fewer lobsters than traps containing an uninfected lobster. Moreover, uninfected lobsters confined in traps with infected lobsters acquired significantly more PaV1 infections than those confined with uninfected lobsters. This study demonstrates the indirect effects that pathogens can have on fisheries and the unintended consequences of certain fishery practices on the epidemiology of a marine pathogen.
Rates of convergence of a transient diffusion in a spectrally negative Lévy potential

We consider a diffusion process X in a random Levy potential V which is a solution of the informal stochastic differential equation {dx t = dβ t - 1/2V'(X t ) dt, X 0 =0, (β B. M. independent of V). We study the rate of convergence when the diffusion is transient under the assumption that the Levy process V does not possess positive jumps. We generalize the previous results of Hu-Shi-Yor for drifted Brownian potentials. In particular, we prove a conjecture of Carmona: provided that there exists 0 < κ < 1 such that E[e κV 1 ] = 1, then X t /t κ converges to some nondegenerate distribution. These results are in a way analogous to those obtained by Kesten-Kozlov-Spitzer for the transient random walk in a random environment.
Angela M . Lee , Seth C . Lewis and Matthew Powers in Online Journalism Audience Clicks and News Placement : A Study of Time-Lagged Influence

The rise of sophisticated tools for tracking audiences online has begun to change the way media producers think about media audiences. This study examines this phenomenon in journalism, building on a revised theoretical model that accounts for greater audience engagement in the gatekeeping process. Research suggests that news editors, after long resisting or ignoring audience preferences, are becoming increasingly aware of and adaptive to consumer tastes as manifest via metrics. However, research also finds a gap in the news preferences of editors and audiences. This study asks: Who influences whom more in this disparity? Through longitudinal secondary data analysis of three U.S. online newspapers, and using structural equation modeling, this study finds that (a) audience clicks affect subsequent news placement, based on time-lagged analysis; (b) such influence intensifies during the course of the day; (c) there is no overall lagged effect of news placement on audience clicks; and (d) the lagged effect of audience clicks on news placement is stronger than the inverse. Implications of these findings and suggestions for future research are discussed.
Magic-wall: Visualizing Room Decoration

This work focuses on Magic-wall, an automatic system for visualizing the effect of room decoration. Given an image of the indoor scene and a preferred color, the Magic-wall can automatically locate the wall regions in the image and smoothly replace the existing color with the required one. The key idea of the proposed Magic-wall is to leverage visual semantics to guide the entire process of color substitution including wall segmentation and color replacement. We propose an edge-aware fully convolutional neural network (FCN) for indoor semantic scene parsing, in which a novel edge-prior branch is introduced to better identify the boundary of different semantic regions. To accurately localize the wall regions, we adapt a semantic-dependent optimized strategy, which pays more attention to those pixels belonging to the wall by adapting larger optimization weights compared with those from other semantic regions. Finally, to naturally replace the color of original walls, a simple yet effective color space conversion method is proposed for replacement with brightness reservation. We build a new indoor scene dataset upon ADE20K for training and testing, which includes 6 semantic labels. Extensive experimental evaluations and visualizations well demonstrate that the proposed Magic-wall is effective and can automatically generate a set of visually pleasing results.
Long-term anhydrobiotic survival in semi-terrestrial micrometazoans

This study represents the first systematic investigation of long-term anhydrobiotic survival in tardigrades, rotifers and nematodes inhabiting mosses and lichens. Sixty-three different samples from public and private collections, kept dry for 9-138 years, were examined. Rotifers of the genus Mniohia and the eutardigrade Ramazzottius oberhaeuseri (hatched from eggs) were found alive from one of the samples (9 years old). These observations represent the longest record for rotifers in the anhydrobiotic state. For tardigrades, our results confirm previous reports on the upper limit of anhydrobiotic survival under atmospheric oxygen conditions. This study suggests the possibility that tardigrade eggs are able to withstand longer periods in anhydrobiosis than animals. Some problems related to the evaluation of long-term anhydrobiotic survival, such as contamination and chemical treatments of samples, are reported. The possible role of the microenvironment in which the anhydrobiotic animals are kept is discussed. (Less)
Australasian Accounting, Business and Finance Journal

Abstract This paper explores corporate sustainability disclosure practices in a global context. A unique sample of 2009 sustainability reports from some of the world’s largest companies in 24 diverse countries are examined using a comprehensive disclosure index. These reports are analysed to better understand how company characteristics and institutional factors explain sustainability communication using a legitimacy theory framework. The world renowned Global Reporting Initiative 2006 guidelines are used as the benchmark disclosure index checklist. The empirical results indicate that the average level of sustainability disclosure is a surprisingly high 61.9 percent. Statistical analysis indicates that high profile industries and additional assurance procedures influence the disclosure of more sustainability information. Interestingly, companies operating in emerging country systems disclose more sustainability information than Anglo-Saxon or Communitarian jurisdictions. Consistent with legitimacy theory, these results suggest that these globally well known firms use sustainability disclosure as a legitimising tool.
Monomer Conversion of Pre-heated Composite

The potential for maximizing conversion of room-temperature, photoactivated resin composite in the oral environment is limited. Pre-heating composite prior to light-curing is hypothesized to increase monomer conversion and reduce the duration of light exposure. Composite temperature was controlled at between 3°C and 60°C prior to exposure with a conventional quartz-tungsten-halogen curing unit: 5, 10, 20, or 40 sec. Monomer conversion was calculated from infrared spectra at 0 mm (top) and 2-mm-deep surfaces 5 min after light initiation. A strong, positive correlation existed between temperature and monomer conversion: top r2 = 0.999, 2 mm r2 = 0.998. Conversion ranged from 31.6% (3°C) to 67.3% (60°C). The duration of light exposure, reduced by 50 to 75% with pre-heated composite, yielded the same or significantly higher conversion (p = 0.001) than with control (22°C, 20 sec). Both hypotheses were accepted: Pre-heating composite prior to photoactivation provides greater conversion requiring reduced light exposure than with room-temperature composite.
Bioproduction of the aroma compound 2‐Phenylethanol in a solid–liquid two‐phase partitioning bioreactor system by Kluyveromyces marxianus

The rose‐like aroma compound 2‐phenylethanol (2‐PE) is an important fragrance and flavor ingredient. Several yeast strains are able to convert l‐phenylalanine (l‐phe) to 2‐PE among which Kluyveromyces marxianus has shown promising results. The limitation of this process is the low product concentration and productivity primarily due to end product inhibition. This study explored the possibility and benefits of using a solid–liquid Two‐Phase Partition Bioreactor (TPPB) system as an in situ product removal technique. The system applies polymer beads as the sequestering immiscible phase to partition 2‐PE and reduce the aqueous 2‐PE concentration to non‐inhibitory levels. Among six polymers screened for extracting 2‐PE, Hytrel® 8206 performed best with a partition coefficient of 79. The desired product stored in the polymer was ultimately extracted using methanol. A 3 L working volume solid–liquid batch mode TPPB using 500 g Hytrel® as the sequestering phase generated a final overall 2‐PE concentration of 13.7 g/L, the highest reported in the current literature. This was based on a polymer phase concentration of 88.74 g/L and aqueous phase concentration of 1.2 g/L. Even better results were achieved via contact with more polymers (approximately 900 g) with the aqueous phase applying a semi‐continuous reactor configuration. In this system, a final 2‐PE concentration (overall) of 20.4 g/L was achieved with 1.4 g/L in the aqueous and 97 g/L in the polymer phase. The overall productivities of these two reactor systems were 0.38 and 0.43 g/L h, respectively. This is the first report in the literature of the use of a polymer sequestering phase to enhance the bioproduction of 2‐PE, and exceeds the performance of two‐liquid phase systems in terms of productivity as well as ease of operation (no emulsions) and ultimate product recovery. Biotechnol. Bioeng. 2009; 104: 332–339 © 2009 Wiley Periodicals, Inc.
Real-Time Object Tracking via Fusion of Global and Local Appearance Models

In this letter, we propose a robust and fast tracking framework by combining local and global appearance models to cope with partial occlusion and pose variations. The global appearance model is represented by a correlation filter to efficiently estimate the movement of the target and the local appearance model is represented by local feature points to handle partial occlusion and scale variations. Then global and local appearance models are unified via the Bayesian inference in our tracking framework. We experimentally demonstrate the effectiveness of the proposed method in both terms of accuracy and time complexity, which takes 12ms per frame on average for benchmark datasets. key words: object tracking, occlusion reasoning, scale estimation, correlation filter
Multi-temporal airborne remote sensing of intertidal sediment dynamics

Coastal remote sensing applications are regularly confined to single image 'snapshot' approaches which do not resolve the dynamic processes in the required temporal resolution. This paper reports the results of a project in which the dynamics of tidal sedimentation were monitored by multi-temporal airborne remote sensing in 10 minute time steps. The radiance data was then converted to estimates of suspended particulate matter loading by the inversion of a hydro-optical analytical model. The results demonstrate that multi-temporal coastal remote sensing can provide information about such dynamic processes that realistically can not be obtained by field-based research methods.
Identification of a circulating microvesicle protein network involved in ST-elevation myocardial infarction

Summary Membrane microvesicles (MVs) are released from activated cells, most notably platelets, into the circulation. They represent an important mode of intercellular communication, and their number is increased in patients with acute coronary syndromes. We present here a differential proteomic analysis of plasma MVs from ST-elevation myocardial infarction (STEMI) patients and stable coronary artery disease (SCAD) controls. The objective was the identification of MVs biomarkers/drug targets that could be relevant for the pathogenesis of the acute event. Proteome analysis was based on 2D-DIGE, and mass spectrometry. Validations were by western blotting in an independent cohort of patients and healthy individuals. A systems biology approach was used to predict protein-protein interactions and their relation with disease. Following gel image analysis, we detected 117 protein features that varied between STEMI and SCAD groups (fold change cut-off ≥2; p<0.01). From those, 102 were successfully identified, corresponding to 25 open-reading frames (ORFs). Most of the proteins identified are involved in inflammatory response and cardiovascular disease, with 11 ORFs related to infarction. Among others, we report an up-regulation of α2-macroglobulin isoforms, fibrinogen, and viperin in MVs from STEMI patients. Interestingly, several of the proteins identified are involved in thrombogenesis (e.g. α2-macroglobulin, and fibrinogen). In conclusion, we provide a unique panel of proteins that vary between plasma MVs from STEMI and SCAD patients and that might constitute a promising source of biomarkers/drug targets for myocardial infarction.