Miracle-dz/UniFAR-FTUs huggingface dataset:
Development of a cyber security awareness strategy using focus group discussion

Focus group discussion is often used as an exploratory technique and serves as a source of data collection. It typically consists of a group of 5 to 10 participants led by a moderator. This work contributes to developing a cyber security master plan in Malaysia through focus group discussion. For this study, thirty-two (32) participants took part in focus group discussions. The background of the participants varied from management, policy-making, law enforcement and prosecution to the research and technical fields. The participants had a range of working experience. The target groups identified are kids, youths, adults and parents, and organizations (both public and private sectors). The overall results suggest that in order to achieve a successful cyber security awareness implementation strategy, three implementation layers are recommended: strategic, program execution and content development layers. The findings provide a holistic approach to developing a single common platform for cyber security awareness programs in Malaysia that encompasses various stakeholders.
Decomposing Discussion Forums and Boards Using User Roles

Discussion forums are a central part of Web 2.0 and Enterprise 2.0 infrastructures. The health and sustainability of forums is dependent on the information exchange behaviour of its contributors, which is expressed through online conversation. The increasing popularity and importance of forums requires a better understanding and characterisation of communication behaviour so that forums can be better managed, new services delivered and opportunities and risks detected. In this paper, we present an empirical analysis of user communication roles in a medium-sized bulletin board and we analyse the composition of several forums in terms of these roles, demonstrating similarities between forums based on underlying user behaviour rather than topic.
Antimicrobial resistance in Salmonella enterica serovar Enteritidis in Morocco.

INTRODUCTION Salmonella enterica is recognised worldwide as one of the major agents of human gastrointestinal infections. The aim of the present work is to ascertain the antimicrobial susceptibilities of 150 Salmonella enterica serovar Enteritidis isolates from humans in Morocco during the period from 2000 to 2008. METHODOLOGY Antimicrobial resistance determination was performed by disk diffusion method using seven antibiotics. The minimal inhibitory concentration (MIC) of ciprofloxacin was determined for nalidixic acid-resistant (NAR) isolates using E-test strips. RESULTS Sixty-one (42%) isolates were resistant to at least one class of antimicrobial agent. The largest numbers of resistant isolates were observed for nalidixic acid with 53 isolates (36%) followed by ampicillin with 7 isolates (5%), tetracycline with 6 isolates (4%), and trimethoprim/sulfamethoxazole with 2 isolates (1%). The resistant isolates were grouped in seven different resistance patterns of which two isolates were resistant to three antibiotics. Among the 53 (36%) NAR isolates, 37 (76%) had a reduced susceptibility to ciprofloxacin. CONCLUSION Resistance rates of Salmonella enterica serovar Enteritidis from Morocco are generally low but the resistance to nalidixic acid is worryingly common. Continual surveillance of antibiotic resistance is of primary importance.
Physical Activity and Bone Health Position Stand

Weight-bearing physical activity has beneficial effects on bone health across the age spectrum. Physical activities that generate relatively highintensity loading forces, such as plyometrics, gymnastics, and high-intensity resistance training, augment bone mineral accrual in children and adolescents. Further, there is some evidence that exercise-induced gains in bone mass in children are maintained into adulthood, suggesting that physical activity habits during childhood may have long-lasting benefits on bone health. It is not yet possible to describe in detail an exercise program for children and adolescents that will optimize peak bone mass, because quantitative dose-response studies are lacking. However, evidence from multiple small randomized, controlled trials suggests that the following exercise prescription will augment bone mineral accrual in children and adolescents:
TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases

NF-κB activation depends on the IKK complex consisting of the catalytically active IKK1 and 2 subunits and the scaffold protein NEMO. Hitherto, IKK2 activation has always been associated with IκBα degradation, NF-κB activation, and cytokine production. In contrast, we found that in SCF-stimulated primary bone marrow-derived mast cells (BMMCs), IKK2 is alternatively activated. Mechanistically, activated TAK1 mediates the association between c-Kit and IKK2 and therefore facilitates the Lyn-dependent IKK2 activation which suffices to mediate mitogenic signaling but, surprisingly, does not result in NF-κB activation. Moreover, the c-Kit-mediated and Lyn-dependent IKK2 activation is targeted by MyD88-dependent pathways leading to enhanced IKK2 activation and therefore to potentiated effector functions. In neoplastic cells, expressing constitutively active c-Kit mutants, activated TAK1 and IKKs do also not induce NF-κB activation but mediate uncontrolled proliferation, resistance to apoptosis and enables IL-33 to mediate c-Kit-dependent signaling. Together, we identified the formation of the c-Kit-Lyn-TAK1 signalosome which mediates IKK2 activation. Unexpectedly, this IKK activation is uncoupled from the NF-κB-machinery but is critical to modulate functional cell responses in primary-, and mediates uncontrolled proliferation and survival of tumor-mast cells. Therefore, targeting TAK1 and IKKs might be a novel approach to treat c-Kit-driven diseases.
Variations of Plasmid Content in Rickettsia felis

Background Since its first detection, characterization of R. felis has been a matter of debate, mostly due to the contamination of an initial R. felis culture by R. typhi. However, the first stable culture of R. felis allowed its precise phenotypic and genotypic characterization, and demonstrated that this species belonged to the spotted fever group rickettsiae. Later, its genome sequence revealed the presence of two forms of the same plasmid, physically confirmed by biological data. In a recent article, Gillespie et al. (PLoS One. 2007;2(3):e266. ) used a bioinformatic approach to refute the presence of the second plasmid form, and proposed the creation of a specific phylogenetic group for R. felis. Methodology/Principal Findings In the present report, we, and five independent international laboratories confirmed unambiguously by PCR the presence of two plasmid forms in R. felis strain URRWXCal2 T, but observed that the plasmid content of this species, from none to 2 plasmid forms, may depend on the culture passage history of the studied strain. We also demonstrated that R. felis does not cultivate in Vero cells at 37°C but generates plaques at 30°C. Finally, using a phylogenetic study based on 667 concatenated core genes, we demonstrated the position of R. felis within the spotted fever group. Significance We demonstrated that R. felis, which unambiguously belongs to the spotted fever group rickettsiae, may contain up to two plasmid forms but this plasmid content is unstable.
Multipoint High-Fidelity Aerostructural Optimization of a Transport Aircraft Configuration

This paper presents multipoint high-fidelity aerostructural optimizations of a long-range wide-body transonic transport aircraft configuration. The aerostructural analysis employs Euler computational fluid dynamics with a 2-million-cell mesh and a structural finite-element model with 300,000 degrees of freedom. The coupled adjoint sensitivity method is used to efficiently compute gradients, enabling the use of gradient-based optimization with respect to hundreds of aerodynamic shape and structural sizing variables. The NASA Common Research Model is used as the baseline configuration, together with a wing box structure that was designed for this study. Two design optimization problems are solved: one where takeoff gross weight is minimized, and another where fuel burn is minimized. Each optimization uses a multipoint formulation with five cruise conditions and two maneuver conditions. Each of the optimization problems have 476 design variables, including wing planform, airfoil shape, and structural thickne.
Causal Relation Extraction

This paper presents a supervised method for the detection and extraction of Causal Relations from open domain text. First we give a brief outline of the definition of causation and how it relates to other Semantic Relations, as well as a characterization of their encoding. In this work, we only consider marked and explicit causations. Our approach first identifies the syntactic patterns that may encode a causation, then we use Machine Learning techniques to decide whether or not a pattern instance encodes a causation. We focus on the most productive pattern, a verb phrase followed by a relator and a clause, and its reverse version, a relator followed by a clause and a verb phrase. As relators we consider the words as, after, because and since. We present a set of lexical, syntactic and semantic features for the classification task, their rationale and some examples. The results obtained are discussed and the errors analyzed.
Autosomal recessive epilepsy associated with contactin 2 mutation is different from familial cortical tremor, myoclonus and epilepsy.

ARTICLE Sir, In a recent interesting paper, Stogmann et al. (2013) described a consanguineous Egyptian family with autosomal recessively inherited condition featuring focal epilepsy, neuropsychiatric features, borderline cognitive level, and myoclonus. Exome sequencing in this family revealed a homozygous deletion (c.503_503delG) leading to a frameshift in the coding region of CNTN2 and segregating in the five affected family members. The gene CNTN2 encodes for contactin 2, a glycosylphosphatidylinositol-anchored neuronal membrane protein, necessary to maintain voltage-gated potassium channels at the juxtaparanodal region. Given the severity of the mutation and the function of the protein, the authors considered this mutation as the most likely cause of the clinical phenotype in this family (Stogmann et al. , 2013). However, we would recommend caution when describing this family as affected by ‘familial …
Genome Properties and Prospects of Genomic Prediction of Hybrid Performance in a Breeding Program of Maize

Maize (Zea mays L.) serves as model plant for heterosis research and is the crop where hybrid breeding was pioneered. We analyzed genomic and phenotypic data of 1254 hybrids of a typical maize hybrid breeding program based on the important Dent × Flint heterotic pattern. Our main objectives were to investigate genome properties of the parental lines (e.g., allele frequencies, linkage disequilibrium, and phases) and examine the prospects of genomic prediction of hybrid performance. We found high consistency of linkage phases and large differences in allele frequencies between the Dent and Flint heterotic groups in pericentromeric regions. These results can be explained by the Hill–Robertson effect and support the hypothesis of differential fixation of alleles due to pseudo-overdominance in these regions. In pericentromeric regions we also found indications for consistent marker–QTL linkage between heterotic groups. With prediction methods GBLUP and BayesB, the cross-validation prediction accuracy ranged from 0.75 to 0.92 for grain yield and from 0.59 to 0.95 for grain moisture. The prediction accuracy of untested hybrids was highest, if both parents were parents of other hybrids in the training set, and lowest, if none of them were involved in any training set hybrid. Optimizing the composition of the training set in terms of number of lines and hybrids per line could further increase prediction accuracy. We conclude that genomic prediction facilitates a paradigm shift in hybrid breeding by focusing on the performance of experimental hybrids rather than the performance of parental lines in testcrosses.
Effects of self-affirmation on message persuasiveness: a cross-cultural study of the U.S. and South Korea

ABSTRACT Much research on public communication campaigns has shown that the negative appeals (e.g. fear, guilt appeals) commonly used may not be effective for encouraging prosocial behaviors, as they can facilitate defensive processing. Self-affirmation theory suggests that self-affirmation may be a useful strategy for mitigating defensive responses to potentially self-threatening messages. This cross-national study explored the effect of self-affirmation on the persuasiveness of a threat appeal message in the context of climate change. An experiment with a 3 (no affirmation versus message-integrated affirmation versus message-separate affirmation) × 2 (high self-threatening versus low self-threatening message) × 2 (U.S. versus Korea) factorial design (N = 225, U.S.; N = 255, Korea) was employed to test this postulation. The results suggested that self-affirmation has a positive effect on perceived risk, attitude toward message, and intention to engage in environmentally-friendly behaviors, although this effect is limited to high self-threat conditions. Additionally, a statistically significant interaction between self-affirmation and culture was found for the effect on behavioral intention. Finally, message-integrated affirmation manipulation was found to be as effective as message-separate affirmation manipulation. The implications of these findings for public communication campaigns in terms of promoting prosocial behaviors are discussed.
Should the allocation of cadaveric kidneys for transplantation be based on HLA matching?

In 1996 the European centres participating in the Eurotransplant organization agreed to the implementation of a new allocation system for kidneys of postmortal donors (Eurotransplant Kidney Allocation System, ETKAS). The proposed procedure was based on the following five criteria: HLA mismatch grade, waiting time, mismatch probability (a correction factor increasing the chances for patients with uncommon HLA phenotypes and for homozygous or immunized patients), local transplants (kidneys are shipped only if the HLA match is at least two match grades better than the best compatible local patient), and import‐ export balance per centre. In the course of time several changes have been made in the original procedure, but the basic principles are still used for the exchange of kidneys within Eurotransplant. The brief report of Gillich et al. [1] in the current issue of the journal raises the question of whether the exchange based on HLA matching is still offering an advantage. In a single-centre study the transplant team in Bonn compared the fate of 77 pairs of kidneys of which one was transplanted locally and the other was offered to Eurotransplant for exchange to another centre. For the locally used kidney no attempt to match for HLA antigens with the recipient was made. Consequently, the mean mismatch grade of the local kidney transplants was almost twice that of the exchanged kidneys. Despite this difference in HLA matching, 1-year and 5-year graft survival rates of the kidney pairs did not differ. As expected cold ischaemia time of the locally used kidneys was considerably shorter. The results suggest that HLA matching is not a conditio sine qua non for a successful renal transplantation and that, with current immunosuppressive protocols, ischaemia time has become a more decisive factor. The results are of interest because the study was systematically performed by a single centre and paired kidneys from the same donor were compared. As the authors acknowledge it also has its limitations. The number of patients is relatively small and the waiting times of the recipients in both groups differ. Also, the immunosuppressive protocols used were most likely not similar in the different centres. They advise to perform larger studies to settle this question.
The impact of relationship‐contingent self‐esteem on mate retention and reactions to threat

Correspondence Christopher J. Holden, Department of Psychology, Appalachian State University, P.O. Box 32109, 222 Joyce Lawrence Lane, Boone, NC 28608. Email: holdencj@appstate.edu Relationship-contingent self-esteem (RCSE) refers to when feelings of self-worth are derived from romantic relationships. RCSE influences views of the self and the functioning of romantic relationships. The relationship between RCSE and mate retention behaviors was examined across three studies. Study 1 examined whether self-esteem level and RCSE predicted mate retention behaviors. Studies 2 and 3 examined whether self-esteem level and RCSE predicted mate retention behaviors following manipulations of threat to the relationship. Individuals with high RCSE were more likely to engage in benefit-provisioning mate retention behaviors, particularly following certain threats. RCSE was also associated with cost-inflicting mate retention behaviors, but these associations were inconsistent.
A global stability result for primal-dual congestion control algorithms with routing

We prove a global stability result for a fluid approximation of a class of Internet-like communications networks operating a form of congestion control with routing. The network consists of an arbitrary interconnection of sources and links with negligible propagation delays. The model here allows for arbitrary strictly concave utility functions and the presence of dynamics at both sources and links.
Detection of Favorable QTL Alleles and Candidate Genes for Lint Percentage by GWAS in Chinese Upland Cotton

Improving cotton yield is a major breeding goal for Chinese upland cotton. Lint percentage is an important yield component and a critical economic index for cotton cultivars, and raising the lint percentage has a close relationship to improving cotton lint yield. To investigate the genetic architecture of lint percentage, a diversity panel consisting of 355 upland cotton accessions was grown, and the lint percentage was measured in four different environments. Genotyping was performed with specific-locus amplified fragment sequencing (SLAF-seq). Twelve single-nucleotide polymorphisms (SNPs) associated with lint percentage were detected via a genome-wide association study (GWAS), in which five SNP loci distributed on chromosomes At3 (A02) and At4 (A08) and contained two major-effect QTLs, which were detected in the best linear unbiased predictions (BLUPs) and in more than three environments simultaneously. Furthermore, favorable haplotypes (FHs) of two major-effect QTLs and 47 putative candidate genes in the two linkage disequilibrium (LD) blocks of these associated loci were identified. The expression levels of these putative candidate genes were estimated using RNA-seq data from ten upland cotton tissues. We found that Gh_A02G1268 was very highly expressed during the early fiber development stage, whereas the gene was poorly expressed in the seed. These results implied that Gh_A02G1268 may determine the lint percentage by regulating seed and fiber development. The favorable QTL alleles and candidate genes for lint percentage identified in this study will have high potential for improving lint yield in future Chinese cotton breeding programs.
Analysis of the carbon-rich very metal-poor dwarf G77-61

We present an analysis of the carbon dwarf G77–61, a known binary, based on high resolution Keck spectra. G77–61 has a very-low metallicity, although not as extreme as what was previously conjectured. This star is very carbon-enhanced, the spectra showing very strong CH, CN, and C 2 bands of both 13 C and 12 C isotopes. Atomic lines are sparse, and often blended, but we were able to derive abundances for Na, Mg, Ca, Cr, Mn, and Fe. Its [Fe/H] of -4.03 ± 0.1 places it among the lowest metallicity stars known, and its very high [C/Fe] = +2.6 , and [N/Fe] = +2.6 among the most C and N-rich metal-poor stars. The carbon isotopic ratio is 12 C/ 13 C = 5 ± 1. No overabundance of s- or r-process elements is detectable, but the upper limits that can be set on these overabundances are not very constraining.
Mebeverine for Pediatric Functional Abdominal Pain: A Randomized, Placebo-Controlled Trial

We evaluated the effectiveness of an antispasmodic, mebeverine, in the treatment of childhood functional abdominal pain (FAP). Children with FAP (n = 115, aged 6–18 years) received mebeverine (135 mg, twice daily) or placebo for 4 weeks. Response was defined as ≥2 point reduction in the 6-point pain scale or “no pain. ” Physician-rated global severity was also evaluated. Patients were followed up for 12 weeks. Eighty-seven patients completed the trial (44 with mebeverine). Per-protocol and intention-to-treat (ITT) analyses were conducted. Treatment response rate in the mebeverine and placebo groups based on per-protocol [ITT] analysis was 54.5% [40.6%] and 39.5% [30.3%] at week 4 (P = 0.117 [0.469]) and 72.7% [54.2%] and 53.4% [41.0] at week 12, respectively (P = 0.0503 [0.416]). There was no significant difference between the two groups in change of the physician-rated global severity score after 4 weeks (P = 0.723) or after 12 weeks (P = 0.870) in per-protocol analysis; the same results were obtained in ITT analysis. Mebeverine seems to be effective in the treatment of childhood FAP, but our study was not able to show its statistically significant effect over placebo. Further trials with larger sample of patients are warranted.
Stable and optimal fuzzy control of a laboratory Antilock Braking System

This paper discusse four new Takagi-Sugeno fuzzy controllers (T-S FCs) for the longitudinal slip control of an Antilock Braking System laboratory equipment. Two discrete-time dynamic Takagi-Sugeno fuzzy models of the controlled plant are derived based on the parameters in the consequents of the rules using the domains of the input variables, and doing the local linearization of the plant model. The original T-S FCs are designed by parallel distributed compensation to obtain the state feedback gain matrices in the consequents of the rules. Two T-S FCs are tuned by imposing relaxed stability conditions to the fuzzy control systems (FCSs) and the other two T-S FCs are tuned by the linear-quadratic regulator approach applied to each rule. Linear matrix inequalities are solved to guarantee the global stability of the FCSs. Real-time experimental results validate the original T-S FCs and design approaches.
The experience of successful smoking cessation: A phenomenological inquiry

The Experience of Successful Smoking Cessation: A Phenomenological Inquiry by Gail Ann Rattigan Dr. Susan Kowalski, Examination Committee Chair Assistant Professor o f Nursing University of Nevada, Las Vegas Cigarette smoking is a significant public health issue and despite efforts, prevalence o f smoking has not decreased in accordance with national goals. This study utilized a phenomenological approach to describe women’s experience o f successful smoking cessation. Pender’s Health Promotion Model (1996) and Prochaska and DiClementes’ Transtheoretical Model of Change (1996) were utilized. Twelve women who had successfully quit smoking were interviewed. Data analysis yielded a core theme of transformation to non-smoker. Sub-themes included motivational factors o f image conflict and cues for action. Other themes included barriers to cessation and coping mechanisms. Interpersonal factors and unconditional resolve were influential. Activity-related affect included grief and loss during cessation and joy and fulfillment upon success.