Miracle-dz/UniFAR-FTUs huggingface dataset:
Studies on the surface of high-performance alloys machined by micro-EDM

ABSTRACT Micro-electrical discharge machining (EDM) is used in the fabrication of Ti-6Al-4V, SUS304, and SKH59 alloys, which are important aviation materials. EDM influences the surface morphologies of these materials and directly affects their reliability during use. However, current research focusing on the morphology of surfaces machined by micro-EDM is rare. Traditional surface evaluation parameter such as Ra cannot describe the surface morphology machined by micro-EDM precisely. Therefore, systematic research on surface morphology of the aforementioned alloys is presented in the study. Based on a novel evaluation method combining fractal theory with wavelet filters, first, comparative experiments on surface morphology evaluations of different materials were conducted and discussed. Second, two different pulse power supplies were studied to explore the effect of pulse power on the high-performance alloy surface. Third, three different micro-EDM processing methods were compared to study their effects on the surfaces of high-performance alloys. Finally, different machining parameters such as discharging energies, rotation speeds of the tool electrode, and gap voltages were set to investigate their effects on the surface morphology. The results showed that different materials, pulse power supplies, processing methods, and machining parameters greatly influence the surface morphology quality, and appropriate machining advice is proposed.
Costing Analysis of National HIV Treatment and Care Program in Vietnam

Background:Vietnam achieved rapid scale-up of antiretroviral therapy (ART), although external funds are declining sharply. To achieve and sustain universal access to HIV services, evidence-based planning is essential. To date, there had been limited HIV treatment and care cost data available in Vietnam. Methods:Cost data of outpatient and inpatient HIV care were extracted at 21 sentinel facilities (17 adult and 4 pediatric) that epitomize the national program. Step-down costing for administration costs and bottom-up resource costing for drugs, diagnostics, and labor were used. Records of 1401 adults and 527 pediatric patients were reviewed. Results:Median outpatient care costs per patient-year for pre-ART, first year ART, later year ART, and second-line ART were US $100, US $316, US $303, and US $1557 for adults; and US $171, US $387, US $320, and US $1069 for children, respectively. Median inpatient care cost per episode was US $162 for adults and US $142 for children. Non-antiretroviral (ARV) costs in adults at stand-alone facilities were 44% (first year ART) and 24% (later year ART) higher than those at integrated facilities. Adults who started ART with CD4 count ⩽100 cells per cubic millimeter had 47% higher non-ARV costs in the first year ART than those with CD4 count >100 cells per cubic millimeter. Adult ARV drug costs at government sites were from 66% to 85% higher than those at donor-supported sites in the first year ART. Conclusions:The study found that HIV treatment and care costs in Vietnam are economical, yet there is potential to further promote efficiency through strengthening competitive procurement, integrating HIV services, and promoting earlier ART initiation.
Comparison of shear bond strength of calcium-enriched mixture cement and mineral trioxide aggregate to composite resin.

AIM Adhesion of composite resin and pulp capping biomaterials remarkably influences treatment outcomes. This in vitro study aimed to compare the shear bond strength of composite resin to calcium enriched mixture (CEM) cement, mineral trioxide aggregate (MTA) and resin modified glass ionomer (RMGI) with or without acid etching. MATERIALS AND METHODS A total of 90 cylindrical acrylic blocks containing a central hole, measuring 4 mm diameter and 2 mm height were prepared. The blocks were randomly divided into three experimental groups based on being filled with CEM, MTA or RMGI. Samples in each group were then randomly divided into two subgroups, i.e. with or without phosphoric acid etching. Placing composite resin cylinders on the samples, shear bond strengths were measured using a universal testing machine. Failure modes of the samples were evaluated under a stereomicroscope. Data were analyzed using two-way ANOVA and Tukey tests. RESULTS Shear bond strengths in the etched and nonetched samples were not significantly different (p = 0.60). There was a significant difference in shear bond strength values of the three experimental materials (p < 0.001) and RMGI showed the highest strength values (p < 0.001); no significant difference was observed between MTA and CEM (p = 0.51). The interaction of the type of material and surface etching was statistically significant (p < 0.001). All of the samples showed cohesive failure mode. CONCLUSION Acid etching of MTA, CEM and RMGI do not improve the shear bond strength of these materials to composite resin. Besides, shear bond strength values of MTA and CEM to composite resin, are favorable due to their cohesive mode of failure. CLINICAL SIGNIFICANCE When MTA and CEM biomaterials are used in vital pulp therapy, it is advisable to cover these materials with RMGI. In addition, if it is not possible to use RMGI, the surface etching of MTA and CEM biomaterials is not necessary prior to composite restoration using total-etch adhesive resin.
Comments on "Wide-sense nonblocking multicast Log2(N, m, p) Networks"

Recently, Hwang and Lin derived nonblocking conditions for multicast connections in Log2(N,m,p) networks. They improved some conditions obtained earlier by Kabacinacuteski and Danilewicz. In this letter, we identify some inaccuracy in present results concerning wide-sense nonblocking Log2(N,m,p) multicast networks, and give the correct results
Heart Failure in the Emergency Department: Treatment Impact and Short-Term Outcomes

3 Background . 4 What is Heart Failure? 4 Characteristics of the HF Population . 5 Prevalence of Heart Failure in the U.S. . 6 Financial Burden of Heart Failure Treatment . 6 Management of Heart Failure in the Emergency Department . 7 Problems Associated with ED Treatment of Heart Failure: The Role of This Study . 12 Data Collection . 16 Results & Discussion . 20 Characteristics of Study Population . 20 Population Validation . 20 ED Length of Stay . 22 Early Diuretic Administration . 23 Conclusions: Limitations and Areas for Future Research . 25 References . 27
“A little on the heavy side”: a qualitative analysis of parents' and grandparents' perceptions of preschoolers' body weights

Objectives Parents’ difficulties in perceiving children's weight status accurately pose a barrier for family-based obesity interventions; however, the factors underlying weight misinterpretation still need to be identified. This study's objective was to examine parents and grandparents’ perceptions of preschoolers’ body sizes. Interview questions also explored perceptions of parental responsibility for childhood obesity and appropriate contexts in which to discuss preschoolers’ weights. Design Semistructured interviews, which were videotaped, transcribed and analysed qualitatively. Setting Eugene and the Springfield metropolitan area, Oregon, USA Participants Families of children aged 3–5 years were recruited in February—May 2011 through advertisements about the study, published in the job seekers’ sections of a classified website (Craigslist) and in a local newspaper. 49 participants (22 parents and 27 grandparents, 70% women, 60% with overweight/obesity) from 16 low-income families of children aged 3–5 years (50% girls, 56% with overweight/obesity) were interviewed. Results There are important gaps between clinical definitions and lay perceptions of childhood obesity. While parents and grandparents were aware of their preschoolers’ growth chart percentiles, these measures did not translate into recognition of children's overweight or obesity. The participants spoke of obesity as a problem that may affect the children in the future, but not at present. Participants identified childhood obesity as being transmitted from one generation to the next, and stigmatised it as resulting from ‘lazy’ parenting. Parents and grandparents avoided discussing the children's weights with each other and with the children themselves. Conclusions The results suggest that clinicians should clearly communicate with parents and grandparents about the meaning and appearance of obesity in early childhood, as well as counteract the social stigma attached to obesity, in order to improve the effectiveness of family-based interventions to manage obesity in early childhood.
Super-Linear Convergence of Dual Augmented Lagrangian Algorithm for Sparsity Regularized Estimation

We analyze the convergence behaviour of a recently proposed algorithm for regularized estimation called Dual Augmented Lagrangian (DAL). Our analysis is based on a new interpretation of DAL as a proximal minimization algorithm. We theoretically show under some conditions that DAL converges super-linearly in a non-asymptotic and global sense. Due to a special modelling of sparse estimation problems in the context of machine learning, the assumptions we make are milder and more natural than those made in conventional analysis of augmented Lagrangian algorithms. In addition, the new interpretation enables us to generalize DAL to wide varieties of sparse estimation problems. We experimentally confirm our analysis in a large scale l1-regularized logistic regression problem and extensively compare the efficiency of DAL algorithm to previously proposed algorithms on both synthetic and benchmark data sets.
Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation

MicroRNA (miRNA) expression profiling of colorectal cancer (CRC) are often inconsistent among different studies. To determine candidate miRNA biomarkers for CRC, we performed an integrative analysis of miRNA expression profiling compared CRC tissues and paired neighboring noncancerous colorectal tissues. Using robust rank aggregation method, we identified a miRNA set of 10 integrated-signature miRNAs. In addition, the qRT-PCR validation demonstrated that 9 miRNAs were consistent dysregulated with the integrative analysis in CRC tissues, 4 miRNAs (miR-21-5p, miR-183-5p, miR-17-5p and miR-20a-5p) were up-regulated expression, and 5 miRNAs (miR-145-5p, miR-195-5p, miR-139-5p, miR-378a-5p and miR-143-3p) were down-regulated expression (all p < 0.05). Consistent with the initial analysis, 7 miRNAs were found to be significantly dysregulated in CRC tissues in TCGA data base, 4 miRNAs (miR-21-5p, miR-183-5p, miR-17-5p and miR-20a-5p) were significantly up-regulated expression, and 3 miRNAs (miR-145-5p, miR-139-5p and miR-378a-5p) were significantly down-regulated expression in CRC tissues (all p < 0.001). Furthermore, miR-17-5p (p = 0.011) and miR-20a-5p (p = 0.003) were up-regulated expression in the III/IV tumor stage, miR-145-5p (p = 0.028) and miR-195-5p (p = 0.001) were significantly increased expression with microscopic vascular invasion in CRC tissues, miR-17-5p (p = 0.037) and miR-145-5p (p = 0.023) were significantly increased expression with lymphovascular invasion. Moreover, Cox regression analysis of CRC patients in TCGA data base showed miR-20a-5p was correlated with survival (hazard ratio: 1.875, 95%CI: 1.088–3.232, p = 0.024). Hence, the finding of current study provides a basic implication of these miRNAs for further clinical application in CRC.
Chloroplast Biogenesis 60 : Conversion of Divinyl Protochlorophyllide to Monovinyl Protochlorophyllide in Green(ing) Barley, a Dark Monovinyl/Light Divinyl Plant Species.

In higher plants, most of the chlorophyll a is formed via the divinyl and monovinyl chlorophyll monocarboxylic biosynthetic routes. These two routes are strongly interconnected prior to protochlorophyllide formation in barley (Hordeum vulgare L. cv Morex), a dark monovinyl-light divinyl plant species, but not in cucumber (Cucumis sativus L. cv Beit Alpha MR), a dark divinyl-light divinyl plant species (BC Tripathy, CA Rebeiz, 1986 J Biol Chem 261: 13556-13564). It is shown that in dark monovinyl-light divinyl plant species such as barley, the divinyl and monovinyl monocarboxylic routes become interconnected at the level of protochlorophyllide during transition from the divinyl to the monovinyl protochlorophyllide biosynthetic mode. In cucumber, a dark divinyl-light divinyl plant species, in which the monovinyl monocarboxylic biosynthetic route becomes preponderant only after an abnormally long sojourn in darkness, the conversion of divinyl to monovinyl protochlorophyllide does not take place on the barley time-scale of incubation.
Linking online news and social media

Much of what is discussed in social media is inspired by events in the news and, vice versa, social media provide us with a handle on the impact of news events. We address the following linking task: given a news article, find social media utterances that implicitly reference it. We follow a three-step approach: we derive multiple query models from a given source news article, which are then used to retrieve utterances from a target social media index, resulting in multiple ranked lists that we then merge using data fusion techniques. Query models are created by exploiting the structure of the source article and by using explicitly linked social media utterances that discuss the source article. To combat query drift resulting from the large volume of text, either in the source news article itself or in social media utterances explicitly linked to it, we introduce a graph-based method for selecting discriminative terms. For our experimental evaluation, we use data from Twitter, Digg, Delicious, the New York Times Community, Wikipedia, and the blogosphere to generate query models. We show that different query models, based on different data sources, provide complementary information and manage to retrieve different social media utterances from our target index. As a consequence, data fusion methods manage to significantly boost retrieval performance over individual approaches. Our graph-based term selection method is shown to help improve both effectiveness and efficiency.
Completeness of Follow-Up Determines Validity of Study Findings: Results of a Prospective Repeated Measures Cohort Study

Background Current reporting guidelines do not call for standardised declaration of follow-up completeness, although study validity depends on the representativeness of measured outcomes. The Follow-Up Index (FUI) describes follow-up completeness at a given study end date as ratio between the investigated and the potential follow-up period. The association between FUI and the accuracy of survival-estimates was investigated. Methods FUI and Kaplan-Meier estimates were calculated twice for 1207 consecutive patients undergoing aortic repair during an 11-year period: in a scenario A the population’s clinical routine follow-up data (available from a prospective registry) was analysed conventionally. For the control scenario B, an independent survey was completed at the predefined study end. To determine the relation between FUI and the accuracy of study findings, discrepancies between scenarios regarding FUI, follow-up duration and cumulative survival-estimates were evaluated using multivariate analyses. Results Scenario A noted 89 deaths (7.4%) during a mean considered follow-up of 30±28months. Scenario B, although analysing the same study period, detected 304 deaths (25.2%, P<0.001) as it scrutinized the complete follow-up period (49±32months). FUI (0.57±0.35 versus 1.00±0, P<0.001) and cumulative survival estimates (78.7% versus 50.7%, P<0.001) differed significantly between scenarios, suggesting that incomplete follow-up information led to underestimation of mortality. Degree of follow-up completeness (i.e. FUI-quartiles and FUI-intervals) correlated directly with accuracy of study findings: underestimation of long-term mortality increased almost linearly by 30% with every 0.1 drop in FUI (adjusted HR 1.30; 95%-CI 1.24;1.36, P<0.001). Conclusion Follow-up completeness is a pre-requisite for reliable outcome assessment and should be declared systematically. FUI represents a simple measure suited as reporting standard. Evidence lacking such information must be challenged as potentially flawed by selection bias.
Developing and Applying the Propensity Score to Make Causal Inferences: Variable Selection and Stratification

This Monte Carlo simulation examined the effects of variable selection (combinations of confounders with four patterns of relationships to outcome and assignment to treatment) and number of strata (5, 10, or 20) in propensity score analyses. The focus was on how the variations affected the average effect size compared to quasi-assignment without adjustment for bias. Results indicate that if a propensity score model does not include variables strongly related to both outcome and assignment, not only will bias not decrease, but it may possibly increase. Furthermore, models that include a variable highly related to assignment to treatment but do not also include a variable highly related to the outcome could increase bias. In regards to the number of strata, results varied depending on the propensity score model and sample size. In 75% of the models that resulted in a significant reduction in bias, quintiles outperformed the other stratification schemes. In fact, the richer that the propensity score model was (i.e., including multiple covariates of varying relationships to the outcome and to assignment to treatment), the more likely that the model required fewer strata to balance the covariates. In models without that same richness, additional strata were necessary. Finally, the study suggests that when developing a rich propensity score model with stratification, it is crucial to examine the strata for overlap.
Clinical Correlates of Body-Size Distortion

Body-size distortion has been considered a central symptom of eating disorders. We studied 35 female eating-disordered patients and 85 controls using a computer-based body-size estimation technique. We have found almost identical linear relationships between body-size distortion and weight:height ratios in both groups. In the clinical group, distortion scores were not correlated with scores on the Eating Attitudes Test or Beck Depression Inventory but were negatively correlated with body dissatisfaction as measured on the Eating Disorder Inventory. These results raise further questions about the role of body-size distortion both as a diagnostic criterion and as a complicating phenomenon in eating disorders.
Robust score normalization for DTW-based on-line signature verification

In the field of automatic signature verification, a major challenge for statistical analysis and pattern recognition is the small number of reference signatures per user. Score normalization, in particular, is challenged by the lack of information about intra-user variability. In this paper, we analyze several approaches to score normalization for dynamic time warping and propose a new two-stage normalization which detects simple forgeries in a first stage and copes with more skilled forgeries in a second stage. An experimental evaluation is conducted on two data sets with different characteristics, namely the MCYT online signature corpus, which contains over three hundred users, and the SUSIG visual sub-corpus, which contains highly skilled forgeries. The results demonstrate that score normalization is a key component for signature verification and that the proposed two-stage normalization achieves some of the best results on these difficult data sets both for random and for skilled forgeries.
Short glass fiber reinforced ABS and ABS/PA6 composites: Processing and characterization

In this study acrylonitrile-butadiene-styrene (ABS) terpolymer was reinforced with 3-aminopropyltrimethoxysilane (APS)-treated short glass fibers (SGFs). The effects of SGF concentration and extrusion process conditions, such as the screw speed and barrel temperature profile, on the mechanical properties of the composites were examined. Increasing the SGF concentration in the ABS matrix from 10 wt% to 30 wt% resulted in improved tensile strength, tensile modulus and flexural modulus, but drastically lowered the strain-at-break and the impact strength. The average fiber length decreased when the concentration of glass fibers increased. The increase in screw speed decreased the average fiber length, and therefore the tensile strength, tensile modulus, flexural modulus, and impact strength were affected negatively and the strain-at-break was affected positively. The increase in extrusion temperature decreased the fiber length degradation, and therefore the tensile strength, tensile modulus, flexural modulus, and impact strength increased. At higher temperatures the ABS matrix degraded and the mechanical strength of the composites decreased. To obtain a strong interaction at the interface, polyamide-6 (PA6) at varying concentrations was introduced into the ABS/30 wt% SGF composite. The incorporation and increasing amount of PA6 in the composites broadened the fiber length distribution (FLD) owing to the low melt viscosity of PA6. Tensile strength, tensile modulus, flexural modulus, and impact strength values increased with an increase in the PA6 content of the ABS/PA6/SGF systems due to the improved adhesion at the interface, which was confirmed by the ratio of tensile strength to flexural strength as an adhesion parameter. These results were also supported by scanning electron micrographs of the ABS/PA6/SGF composites, which exhibited an improved adhesion between the SGFs and the ABS/PA6 matrix. POLYM. COMPOS. 26:745–755, 2005. © 2005 Society of Plastics Engineers
The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis.

BACKGROUND The Fc gamma RIIIA-V/F158 polymorphism affects immunoglobulins (Ig)G1- and IgG3-binding capacity and may modulate the expression of renal disease in patients with systemic lupus erythematosus (SLE). We aimed to determine whether this polymorphism confers risk for the development of lupus nephritis and SLE in general. METHODS A meta-analysis was performed based on the Medline and Embase databases (last update, August 2002), perusal of abstracts from major meetings (1999 to 2001), assessment of bibliographies of pertinent articles, and additional data gathered after contact with primary investigators. RESULTS A total of 16 comparisons from 11 studies involving V/F158 genotyping of 1154 patients with lupus nephritis, 1261 SLE patients without nephritis, and 1455 disease-free controls were included. Comparison of lupus nephritis patients with non-nephritis SLE subjects revealed a significant overrepresentation of the low-binding F158 allele among patients who developed renal disease [odds ratio (OR) 1.20, 95% confidence interval (95% CI) 1.06 to 1.36, P = 0.003)], without significant between-study heterogeneity. FF homozygotes had the highest risk of renal disease as compared to VV homozygotes (OR 1.47, 95% CI 1.11 to 1.93, P = 0.006). It was uncertain whether the F158 allele influenced susceptibility to SLE per se (OR 1.19, 95% CI 0.99 to 1.43, P = 0.063 for SLE patients without nephritis versus disease-free controls; 0.01 < P < 0.10 for heterogeneity) and the observed trend for an association was driven mostly by the smaller studies (P = 0.058 for publication bias). No such bias was detected for analyses on susceptibility to lupus nephritis. CONCLUSION The Fc gamma RIIIA-V/F158 polymorphism has a significant impact on the development of lupus nephritis.