Miracle-dz/UniFAR-FTUs huggingface dataset:
Uterine Retiform Sertoli-Leydig Cell Tumor: Report of a Case Providing Additional Evidence That Uterine Tumors Resembling Ovarian Sex Cord Tumors Have a Histologic and Immunohistochemical Phenotype of Genuine Sex Cord Tumors

Summary:We report a case of a retiform Sertoli-Leydig cell tumor of intermediate differentiation presenting as a uterine intracavity polypoid mass in a 63-year-old woman. In contrast to sertoliform endometrioid carcinoma and to hitherto reported uterine tumors resembling ovarian sex cord tumors (UTROSCTs), which are primarily characterized by tubular glands and solid tubules, this tumor, which most likely represents a UTROSCT, showed a large spectrum of histologic features typical of a genuine retiform Sertoli-Leydig cell tumor. The diagnosis was confirmed by a battery of immunohistochemical stains, which also served as a tool for differential diagnosis with other neoplasms. The tumor cells were positive for broad spectrum keratin (CK) CK18, vimentin, calretinin, and progesterone receptor. Only a few isolated cells stained for inhibin. The tumor cells were negative for CK7, CK5/6, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), thrombomodulin, 013 (CD99), melan A, alpha-fetoprotein (AFP), placental alkaline phosphatase (PLAP), α-1-antitrypsin, estrogen receptor, S100, neurone specific enolase (NSE), chromogranin, synaptophysin, desmin, caldesmon, and CD10. Divergent differentiation of uterine cells seems to be the most likely pathogenetic mechanism. To the best of our knowledge, no UTROSCT showing such a variety of histologic features indicative of a true sex cord tumor has been reported before.
Materials and Technology for RF-MEMS

MEMS technology is rapidly emerging as an enabling technology to yield a new generation of high-performance RF passives, such as switches, tunable capacitors, high-Q resonators and tunable filters. This paper presents the progress in RF-MEMS device and package development with focus on relevant technology and material issues for RF-MEMS switches, tunable capacitors, MEM resonators and film bulk acoustic resonators. The importance of wafer-level or 0-level packaging of the RFMEMS devices is elucidated. The paper concludes in stipulating how integration of RF-MEMS passives with other passives (as inductors, LC filters, SAW devices) and active circuitry (RFICs) can lead to so-called "RF-MEMS system-in-a-package (RFMEMS-SiP)" modules. The evolution of the RF-MEMS-SiP technology is illustrated using IMEC's microwave multi-layer thin film MCM-D technology.
Improving self‐esteem and reading

Summary A sample of 374 eight‐year‐old retarded readers from 29 schools was allocated to four different treatments: Distar only; Distar plus counselling; Distar plus drama; no special treatment. At the end of 20 weeks the therapeutic treatments produced higher gains in reading and in self‐esteem when contrasted with the non‐therapeutic treatments. The differences between treatments are seen to depend on the initial level of self‐esteem. The results are discussed in relation to their practical significance.
(Re)Positioning the Child in the Policy/Politics of Early Childhood

How a community constructs the notion of childhood and the child is fundamentally implicated in the practices and policies of that community. This article explores the positioning of the child in historical, contemporary and emerging trends in the provision and practices of Australian early childhood education and care. It argues that if left uncontested, emerging contemporary constructions have the potential to normalise policies, practices and pedagogies derived from a commercialised view of childhood. Drawing on the experiences and practices of early childhood pedagogues and policy actors both in Australia and overseas the authors posit an alternative construction of the child as citizen and the possibility of the early childhood field as a site for the practice of democracy.
Utilizing Conjoint Analysis to Explicate Nurse–Patient Interaction Among Geriatric Incarcerated Individuals

There has been no attempt to explicate elderly patients’ preferences during nurse-patient interaction in the context of a prison setting. A purposive sample of 347 was chosen from a national Philippine prison based on the following inclusion criteria: (a) 55 years old and above, (b) incarcerated, (c) no psychological impairment, and (d) can amply read and write. Via conjoint analysis (CA), 36 from 81 nurse–patient interaction cards were produced according to orthogonal plans, as specified by SPSS. The conjoint analysis model proved to be fit: Pearson R = . 993, (p < .05) Kendall's tau = . 944 (p < .05), Kendall's tau for holdouts = . 799 (p < .05). The use of CA showed the top 3 attributes: language (21.26%), smile (18.49%), and eye contact (14.19%). Overall, the following levels are highly preferred by respondents: “vernacular” language (utility = 1.377, SE = .21.26), “with” smile (utility = 1.198, SE = .082), and “constant” eye-contact/gaze (utility = .919, SE = .082). Significant differences in nurse–patient interaction were noted in age brackets, current health condition, and years of incarceration, except in educational attainment. Overall, geriatric incarcerated individuals preferred nurses who verbally utilize close-ended, nonfrequent, and without follow-up questions, speak vernacular in a low and constant intonation, give encouragement, and praise. When touch is needed, the respondents preferred same gender nurses. Respondents find it more comfortable when nurses utilize ‘friendly’ space during the interaction, smile, and maintain constant eye contact. To achieve more consistent care, nursing actions must be in accordance with these preferences.
Retrieval Cues and Release from Proactive Inhibition.

Data from a replication and extension of a 1972 experiment by Gardiner, Craik, and Birtwistle are used to support the arguments that Wickens' shift effect as a measure of encoding may underestimate the number of attributes primed in the course of successive Brown-Peterson trials; that the encoding of such primed attributes is obligatory rather than optional; and that the shift effect, in conformance with the principle of encoding specificity, is a joint phenomenon of both storage and retrieval.
Focused Stochastic Local Search and the Lovász Local Lemma

We develop tools for analyzing focused stochastic local search algorithms. These are algorithms which search a state space probabilistically by repeatedly selecting a constraint that is violated in the current state and moving to a random nearby state which, hopefully, addresses the violation without introducing many new ones. A large class of such algorithms arise from the algorithmization of the Lovasz Local Lemma, a non-constructive tool for proving the existence of satisfying states. Here we give tools that provide a unified analysis of such algorithms and of many more, expressing them as instances of a general framework.
Laboratory-based Surveillance of Extensively Drug-Resistant Tuberculosis, China

To estimate the prevalence of extensively drug-resistant tuberculosis (XDR TB) in China, we retrospectively analyzed drug-resistance profiles of 989 clinical Mycobacterium tuberculosis isolates. We found 319 (32.3%) isolates resistant to >1 first-line drugs; 107 (10.8%) isolates were multidrug resistant, of which 20 (18.7%) were XDR. XDR TB is of major concern in China.
Second-generation image-coding techniques

The digital representation of an image requires a very large number of bits. The goal of image coding is to reduce this number, as much as possible, and reconstruct a faithful duplicate of the original picture. Early efforts in image coding, solely guided by information theory, led to a plethora of methods. The compression ratio, starting at 1 with the first digital picture in the early 1960s, reached a saturation level around 10:1 a couple of years ago. This certainly does not mean that the upper bound given by the entropy of the source has also been reached. First, this entropy is not known and depends heavily on the model used for the source, i.e., the digital image. Second, the information theory does not take into account what the human eye sees and how it sees. Recent progress in the study of the brain mechanism of vision has opened new vistas in picture coding. Directional sensitivity of the neurones in the visual pathway combined with the separate processing of contours and textures has led to a new class of coding methods capable of achieving compression ratios as high as 70:1. Image quality, of course, remains as an important problem to be investigated. This class of methods, that we call second generation, is the subject of this paper. Two groups can be formed in this class: methods using local operators and combining their output in a suitable way and methods using contour-texture descriptions. Four methods, two in each class, are described in detail. They are applied to the same set of original pictures to allow a fair comparison of the quality in the decoded pictures. If more effort is devoted to this subject, a compression ratio of 100:1 is within reach.
Social Resources and Change in Functional Health: Comparing Three Age Groups

This study examined the mediating and moderating role of social resources on the association between age and change in functional health for three age groups of older adults. Data were provided by those in their 60s, 80s, and 100s who participated in the first two phases of the Georgia Centenarian study. Analyses confirmed the study's hypothesis that social resources moderated the relationship between age group and change in functional health; in particular, centenarians who experienced the greatest decline in IADLs scored the highest on social resources at time 1. No evidence was found for mediation by social resources or a directional influence by either level of social resources or functional health on change in the other resource. Evidence from this study challenges researchers and service providers to consider the heterogeneity in resources among older adults.
Seizing the Moment: Talking about the “Undiscussables”

Given the varied backgrounds, experiences, and perspectives among students and faculty in management education and organizational studies programs, often teachable moments present themselves around differing perceptions. Seizing these moments to talk about difficult, controversial issues—or undiscussables—can catalyze and deepen learning. This article delves into the underutilized resource of class conversations for conversational learning. It explores how to prepare more receptive learning environments and how to prepare faculty to facilitate conversational interactions that can promote a more complex level of learning. The article concludes with two illustrations from actual classroom work.
Distinguishing mechanisms of gamma frequency oscillations in human current source signals using a computational model of a laminar neocortical network

Gamma frequency rhythms have been implicated in numerous studies for their role in healthy and abnormal brain function. The frequency band has been described to encompass as broad a range as 30–150 Hz. Crucial to understanding the role of gamma in brain function is an identification of the underlying neural mechanisms, which is particularly difficult in the absence of invasive recordings in macroscopic human signals such as those from magnetoencephalography (MEG) and electroencephalography (EEG). Here, we studied features of current dipole (CD) signals from two distinct mechanisms of gamma generation, using a computational model of a laminar cortical circuit designed specifically to simulate CDs in a biophysically principled manner (Jones et al., 2007, 2009). We simulated spiking pyramidal interneuronal gamma (PING) whose period is regulated by the decay time constant of GABAA-mediated synaptic inhibition and also subthreshold gamma driven by gamma-periodic exogenous excitatory synaptic drive. Our model predicts distinguishable CD features created by spiking PING compared to subthreshold driven gamma that can help to disambiguate mechanisms of gamma oscillations in human signals. We found that gamma rhythms in neocortical layer 5 can obscure a simultaneous, independent gamma in layer 2/3. Further, we arrived at a novel interpretation of the origin of high gamma frequency rhythms (100–150 Hz), showing that they emerged from a specific temporal feature of CDs associated with single cycles of PING activity and did not reflect a separate rhythmic process. Last we show that the emergence of observable subthreshold gamma required highly coherent exogenous drive. Our results are the first to demonstrate features of gamma oscillations in human current source signals that distinguish cellular and circuit level mechanisms of these rhythms and may help to guide understanding of their functional role.
Adding MUFA to a dietary portfolio of cholesterol-lowering foods reduces apoAI fractional catabolic rate in subjects with dyslipidaemia

The present randomised parallel study assessed the impact of adding MUFA to a dietary portfolio of cholesterol-lowering foods on the intravascular kinetics of apoAI- and apoB-containing lipoproteins in subjects with dyslipidaemia. A sample of sixteen men and postmenopausal women consumed a run-in stabilisation diet for 4 weeks. Subjects were then randomly assigned to an experimental dietary portfolio either high or low in MUFA for another 4 weeks. MUFA substituted 13·0 % of total energy from carbohydrate (CHO) in the high-MUFA dietary portfolio. Lipoprotein kinetics were assessed after the run-in and portfolio diets using a primed, constant infusion of [2H3]leucine and multicompartmental modelling. The high-MUFA dietary portfolio resulted in higher apoAI pool size (PS) compared with the low-MUFA dietary portfolio (15·9 % between-diet difference, P= 0·03). This difference appeared to be mainly attributable to a reduction in apoAI fractional catabolic rate (FCR) after the high-MUFA diet ( − 5·6 %, P= 0·02 v. pre-diet values), with no significant change in production rate. The high-MUFA dietary portfolio tended to reduce LDL apoB100 PS compared with the low-MUFA dietary portfolio ( − 28·5 % between-diet difference, P= 0·09), predominantly through an increase in LDL apoB100 FCR (23·2 % between-diet difference, P= 0·04). These data suggest that adding MUFA to a dietary portfolio of cholesterol-lowering foods provides the added advantage of raising HDL primarily through a reduction in HDL clearance rate. Replacing CHO with MUFA in a dietary portfolio may also lead to reductions in LDL apoB100 concentrations primarily by increasing LDL clearance rate, thus potentiating further the well-known cholesterol-lowering effect of this diet.
THE DISTRIBUTION OF PIAGETIAN STAGES OF THINKING IN BRITISH MIDDLE AND SECONDARY SCHOOL CHILDREN

Summary. The proportion of children showing early and late concrete operational thinking, and early and late formal operational thinking was measured in a sample of 10,000 children between the ages of 9 and 14. The test instruments were a form of group test called Class Tasks, derived from the individual interview situations described by Piaget. These tests indicated that most children in early adolescence showed rapid development in concrete thinking, but that only one-fifth of the children showed the further development of formal operational thought. The representativeness of these findings was ensured by relating the distribution of Piagetian stages at each age-level to the norms of a standardised non-verbal reasoning test.
Correlates of HIV Knowledge and Testing

This research explored the correlates of HIV knowledge and testing. The study predicted that there would be significant relationships between knowledge of HIV transmission, and testing for HIV, educational level, and gender. Testing behavior was also predicted to be associated with gender and knowing someone who has HIV/AIDS or someone who has died of the disease. A convenience sample of 429 respondents in the Republic of South Africa participated in the study. Volunteers completed the Carey and Schroder Brief HIV Knowledge Questionnaire and other items pertaining to the study variables. Results from the ANOVA showed that as education level increased, so did knowledge of HIV. Females had more knowledge of HIV than males. An independent samples t test showed that those who had been tested for HIV had more knowledge than those who had not. Chi-Square analyses indicated that as education level increased, so did the frequency of testing; and that knowing someone who has HIV/AIDS or someone who has died of the disease tends to increase testing behavior.
Towards understanding the role of emotions in conflict: a review and future directions

Purpose – This paper attempts to connect the literature on conflict and that of emotions. The argument presented is that emotions have until recently been understudied in conflict literature and vice versa. On the basis of the review of literature on both conflict and emotions, the paper points to new areas of exploration for researchers in both domains.Design/methodology/approach – A literature review of two separate sub‐fields of study, namely conflict and emotions is provided with the intent of pointing towards gaps in connecting the two streams of research and towards a more holistic understanding of the role of emotions in conflict.Findings – It is observed that the link between emotions and conflict has received little attention both in the literature on conflict and that of emotions. Insights into the role of emotions at the time of conflict and towards its subsequent resolution are provided. Future directions for study and potential linkages between the two streams are offered.Originality/value – .
Anticoccidial activity of herbal complex in broiler chickens challenged with Eimeria tenella

SUMMARY The objective of the present study was to evaluate the anticoccidial effect of different concentrations of the herbal complex of 4 plants (leaves of Azadirachta indica and Nicotiana tabacum, flowers of Calotropis procera and seeds of Trachyspermum ammi) in broiler chickens in comparison with amprolium anticoccidial. Three concentrations (2 g, 4 g and 6 g) of herbal complex were given to the experimental groups once a day and amprolium (at the dose rate of 125 ppm) was given orally in drinking water from the 14th to the 21st days of age. One group was kept as infected, non-medicated control and one as non-infected, non-medicated control. All groups were inoculated orally with 75 000 sporulated oocysts on the 14th day of age except the non-infected, non-medicated control. Among herbal complex medicated groups, the maximum anticoccidial effect was seen in the group medicated with 6 g herbal complex followed by 4 g and 2 g herbal complex medicated groups. Treatment with 6 g of the herbal complex significantly reduced the negative performance and pathogenic effects associated with Eimeria tenella challenge at a level that was comparable with amprolium when using a largely susceptible recent field isolate. In summary, concentration-dependent anticoccidial activity of the studied herbal complex suggests its use as an alternative anticoccidial agent to chemotherapeutic drugs for Eimeria tenella control.
Female Rats Fed a High-Fat Diet Were Associated with Vascular Dysfunction and Cardiac Fibrosis in the Absence of Overt Obesity and Hyperlipidemia: Therapeutic Potential of Resveratrol

It remains presently unknown whether vascular reactivity is impaired and whether maladaptive cardiac remodeling occurs before the onset of overt obesity and in the absence of hyperlipidemia. Normal female rats were fed a high-fat diet for 8 weeks and were associated with a modest nonsignificant increase of body weight (standard diet, 300 ± 10, versus high-fat diet, 329 ± 14 g) and a normal plasma lipid profile. In rats fed a high-fat diet, systolic (171 ± 7 mm Hg) and diastolic blood pressures (109 ± 3) were increased compared to a standard diet (systolic blood pressure, 134 ± 8; diastolic blood pressure, 96 ± 5 mm Hg), and acetylcholine-dependent relaxation of isolated aortic rings (high-fat diet, 22 ± 5%, versus standard diet, 53 ± 8%) was significantly reduced. Furthermore, perivascular fibrosis was detected in the heart of rats fed a high-fat diet. The exogenous addition of resveratrol (trans-3,5,4′-trihydroxystilbene) (0.1 μM) to aortic rings isolated from rats fed a high-fat diet restored acetylcholine-mediated relaxation (47 ± 9%). The administration of resveratrol (20 mg/kg/day for 8 weeks) to rats fed a high-fat diet prevented the increase in blood pressure and preserved acetylcholine-dependent relaxation of isolated aortic rings. However, resveratrol therapy failed to attenuate the perivascular fibrotic response. These data have demonstrated that a high-fat diet fed to normal female rats can elicit a hypertensive response and induce perivascular fibrosis before the development of overt obesity and in the absence of hyperlipidemia. Resveratrol therapy can prevent the hypertensive response in female rats fed a high-fat diet but is without effect on the progression of perivascular fibrosis.
Assessing entrepreneurial inclinations: Some approaches and empirical evidence

Interest in entrepreneurship is intense in many parts of the world and this has arisen because of the association between new venture creation and economic development. Entrepreneurship is a process that often leads to the creation of new enterprises but in this article the concept is broadened to include innovative and enterprising behaviour within existing organizations. While it is recognized that entrepreneurs and entrepreneurship are the products of various societal, organizational, and individual factors, this article focuses on the inherent personal traits of individuals that dispose them to engage in entrepreneurial acts. Some approaches to assessing the entrepreneurial personality are examined, but the principal focus is on pencil and paper measures of entrepreneurial attributes. Various instruments that purport to measure key entrepreneurial characteristics such as need for achievement, locus of control, and creative tendencies are considered and relevant empirical evidence is reported. A consideration of the appropriateness of the Durham University Business School's General Enterprising Tendency test as a composite instrument for assessing enterprising or entrepreneurial tendencies follows along with some statistical norms for this test, which should prove useful for practitioners and academics alike. Finally, some problems with trait theories of entrepreneurship are discussed.
Local Knowledge Spillovers, Innovation and Economic Performance in Developing Countries: A discussion of alternative specifications

This paper examines the importance of local knowledge spillovers for the innovative and economic performance of firms in a developing country context. Theoretical and empirical studies in advanced economies underline the significance of local knowledge spillovers for innovation. However, not much is known about whether local knowledge spillovers work similarly in developing countries. This analysis is based on an original innovation survey in the software industry in Uruguay. The survey focuses on the direct identification and measurement of local knowledge spillovers; pure knowledge spillovers are distinguished from commercial knowledge transactions. Both knowledge spillovers and knowledge transactions are measured at the local and at the international level. The study concludes that local knowledge spillovers play a crucial role in enhancing the innovative performance of software firms in Uruguay. However, for the economic performance of the firms, international knowledge transactions turn out to be more important than local knowledge spillovers. Local Knowledge Spillovers may be essential for innovation, but not sufficient for economic success. Firms in developing countries need to be connected to both the local and the international economy.