Miracle-dz/UniFAR-FTUs huggingface dataset:
Coronal structure of the classical T Tauri star V2129 Oph

The nature of the magnetic coupling between T Tauri stars and their discs determines not only the mass accretion process but possibly the spin evolution of the central star. We have taken a recently published surface magnetogram of one moderately accreting T Tauri star (V2129 Oph) and used it to extrapolate the geometry of its large-scale field. We determine the structure of the open (wind-bearing) field lines, the closed (X-ray bright) field lines and the relatively small subset of field lines that pass through the equatorial plane inside the Keplerian corotation radius and which are therefore available to accrete. We consider a series of models in which the stellar magnetic field is opened up by the outward pressure of the hot coronal gas at a range of radii or source surfaces. As the source surface is increased, accretion takes place along progressively simpler field structures and impacts on progressively fewer sites at the stellar surface. This is consistent with the observed variation in the Ca ii IRT and He i lines which suggests that accretion in the visible hemisphere is confined to a single high-latitude spot. By determining the density and velocity of the accretion flows, we find that in order to have most of the total mass accretion rate impacting on a single high-latitude region we need disc material to accrete from approximately 7R⊙, close to the Keplerian corotation radius at 6.8R⊙. We also calculate the coronal density and X-ray emission measure. We find that both the magnitude and rotational modulation of the emission measure increase as the source surface is increased. For the field structure of V2129 Oph which is dominantly octupolar, the emission forms a bright, high-latitude ring that is always in view as the star rotates. Since the accretion funnels are not dense enough to cause significant scattering of coronal X-ray photons, they provide only a low rotational modulation of around 10 per cent at most.
Regionalization of the Telencephalon in Urodele Amphibians and Its Bearing on the Identification of the Amygdaloid Complex

The brain of urodele amphibians has formed the basis for numerous comparative neuroanatomical studies because its simplified arrangement of neurons and fibers was considered to represent the basic pattern common to all tetrapods. However, on the basis of classical histological techniques many common features shared by the brain of amniotes could not be identified in the anamniotic amphibians. Recently, the combined analysis of the chemoarchitecture and hodology has demonstrated that the brain, and particularly the telencephalon, of anuran amphibians shares all major basic features with amniotes. In the present study, we have conducted a series of immunohistochemical detections for telencephalic regional markers (nitric oxide synthase (NOS), γ-amino butyric acid (GABA), Islet-1 (Isl1), and Nkx2.1) that were useful tools for unraveling telencephalic organization in other vertebrates. In addition, the combination of tract-tracing techniques with dextran amines to demonstrate olfactory secondary centers, hypothalamic projections, and brainstem connections has served to propose subdivisions within the amygdaloid complex. The results of the present analysis of the urodele telencephalon using a multiple approach have demonstrated, among other features, the presence of a ventral pallial region, striatopallidal subdivision in the basal ganglia, and three main components of the amygdaloid complex. Therefore, in spite of its apparently simple organization, within the telencephalon of urodeles it is possible to identify most of the features observed in amniotes and anurans that are only revealed with the use of combined modern techniques in neuroanatomy.
Angiotensin-converting enzyme inhibitor renography in the diagnosis of renovascular hypertension. Studies before and after angioplasty.

Renography with [99mTc] diethylenetriaminepenta-acetate (DTPA) was performed in 26 patients with renal artery stenosis (RAS), unilateral in 15 and bilateral in 11, and in 16 patients with essential hypertension with a normal renal angiogram. Nine of the patients with unilateral RAS were restudied after a successful percutaneous transluminal renal angioplasty (PTRA), i.e. complete removal of the stenosis and a normalization of the blood pressure without antihypertensive treatment. Single-kidney [99mTc]-DTPA clearance and parenchymal mean transit time (MTT) were determined at each examination. All patients were studied on two different days using the same procedure except that captopril 25 mg was given orally before renography at the second examination. In unilateral RAS captopril reduced single-kidney [99mTc]-DTPA clearance significantly on the affected side (-42.7%, median) but not on the unaffected side (-3.2%). In bilateral RAS single-kidney [99mTc]-DTPA clearance was reduced to the greatest extent on the most affected side (-43.0%) compared with the least affected side (-17.2%). In essential hypertension no significant changes were recorded on any side (-1.5% for both). After PTRA, single-kidney [99mTc]-DTPA clearance was not significantly changed by captopril either on the previously affected side (4.3%) or on the unaffected side. MTT was significantly prolonged after captopril on the affected side in unilateral RAS and on the most affected side in bilateral RAS, whereas no significant changes were found on the unaffected side in unilateral RAS, on the least affected side in bilateral RAS, or on any side in essential hypertension. (ABSTRACT TRUNCATED AT 250 WORDS)
Inleiding tot de historische geografie van de Nederlandse cultuurlandschappen

Eerst worden de omstandigheden besproken die bijgedragen hebben tot het ontstaan van de Nederlandse cultuurlandschappen en vervolgens passeren deze landschappen afzonderlijk de revue voor op het zand en de loess, op de klei en tenslotte op het veen. Weergave van Stiboka expertise
THE ROLE OF CERTAIN BIVALENT IN CHRONIC PERIODONTITIS

Used abbreviations and shortcuts 7 Miscellaneous 8 Chapter I Structure and functions of human periodontium 9 Attached gingiva 10 Interdental gingiva 11 Periodontal ligaments 11 Components of the periodontium 12 Chapter II – Periodontal disease 16 Classification 16 Chronic periodontitis 21 Ethiology 21 Dental plaque – a host biofilm 22 Clinical features 35 Diagnosis criteria 36 Epidemiology of chronic periodontitis 36 Risk factors in periodontal conditions 37 Chronic periodontitis as a risk factor 38 Chapter III – Pharmacotherapy of periodontal conditions 40 Antibacterial antibiotics 40 Antibiotic prophylaxis in periodontal conditions 40 Antiseptics in the treatment of chronic periodontitits 43 The hydrogen peroxyde 43 Solution Dr. Walkhoff 43 Clorhexidine (CHX) 44 Iod-povidone 45 Steroidal and non-steroidal anti-inflammatories in chronic periodontitis 45 Other drugs 45 Personal part 47 Chapter IV – Motivation of the research 48 Systemic antibiotherapy in periodontology 48 Efficiency of antibiotic prophylaxis in periodontology 49 Drug interactions 50 Infection prevention in view of invasive dental procedures 50 Therapeutic schemes for general antibiotherapy 52 Chapter V – Patients and method 61 Chart design 63 Patient selection 66 Clinical and paraclinical investigations 67 Sampling 69 Treatment of chronic periodontitis 70 Sample processing 70 Data analysis and procressing 71 Data synthesizing as work chart 72 Chapter VI – Results of personal research 73 Dosage of bivalent cations in patients with chronic periodontitis 73 Introduction 73 Calcium 73 Distribution in the human body 73 Calcium intake 74 Physiological role of calcium in teeth and periodontium 74 Hypocalcemia 74 Hypercalcemia 75 Magnesium 75 Distribution in the human body 75 Magnesium intake 76 Physiological roles of magnesium 76 Magnesium in dental and periodontal tissues 77 Hypomagnesemia 78 Hypermagnesemia 79 Copper 79 Distribution in the human body 79 Copper intake 79 Copper elimination 80 Physiological roles of copper 80 Hypocupremia 80 Hypercupremia 81 Zinc 81 Distribution in the human body 81 Zinc intake 81 Physiological roles of zinc 82 Zinc in the periodontal tissues 82 Zinc depletion 83 Aims of the research 86 Patients and methods 86 Results 87 Discussions and conclusions 90 Research on the influence of fixed dental restorations with metal structure on the salivary bivalent cations 9
Bowel Habit and Dietary Fibre Intake Before and During Menstruation

The stool frequency, faecal form and dietary fibre intakes of 25 menstruating women were recorded during the 4 days just before menstruation and the first 4 days of menstruation. At the time of the bleed there was a significant increase (P < 0.01) in stool frequency, a significant decrease (P < 0.001) in faecal form and a significant increase (P < 0.01) in dietary fibre intake. There are indications that cyclical changes in fibre intake may have some bearing on differences in bowel function between the luteal phase and menses although other factors would appear to play a dominant role.
Model-Based Scene Analysis

The general problem of separating multiple sources mixed into a single channel is illposed; in order to solve it, additional constraints must be applied. One very general class of constraints is prior knowledge of the source signals: limitations on the waveforms possible for each source can disambiguate the mixture since there may only be one set of ‘legal’ source signals that would add together to give the observed mixture. A particularly attractive aspect of this approach is that models themselves may be learned from the environment by generalizing across observations of isolated sources. This chapter examines the general idea of using models in source separation including looking at what form these models can take and how they can be acquired, and describes examples of several systems which can be described within this
Role of CD2‐associated protein in albumin overload‐induced apoptosis in podocytes

Proteinuria is a well‐established exacerbating factor of chronic kidney diseases. However, the harmful effects of protein overload on podocytes and the underlying mechanisms are still poorly understood. In the present study, we examined the effects of high concentrations of albumin on podocytes and investigated the role of CD2AP (CD2‐associated protein) in albumin overload‐induced podocyte apoptosis. Conditionally immortalized mouse podocytes were cultured in vitro and treated with different concentrations of BSA. In addition, CD2AP eukaryotic expression vector or siRNA (small interfering RNA) was transfected into podocytes before they were exposed to BSA. Podocyte apoptosis, expressions of active caspase‐3 (p17) and CD2AP, and the distribution of F‐actin cytoskeleton were detected by flow cytometry, Western‐blot analysis and fluorescent staining respectively. It was found that exposure of podocytes to BSA induced podocyte apoptosis in a concentration‐dependent manner that was accompanied by up‐regulation of active caspase‐3, the disruption of F‐actin cytoskeleton, and decreased expression of CD2AP. Transfection of CD2AP eukaryotic expression vector into podocytes increased CD2AP expression, partially restored F‐actin distribution, blocked active caspase‐3 expression and inhibited podocyte apoptosis. In contrast, transfection of CD2AP siRNA deteriorated the above changes induced by BSA. It is concluded that protein overload induces podocyte apoptosis via the down‐regulation of CD2AP and subsequent disruption of cytoskeleton of podocytes, and CD2AP may play an important role in protein overload‐induced podocyte injury.
Approaching Speed-of-light Distortionless Communication for On-chip Interconnect

We extend the surfliner on-chip distortionless transmission line scheme and provide more details for the implementation issues. Surfliner seeks to approach distortionless transmission by intentionally adding shunt resistors between the signal line and the ground. In theory if we distributively make the shunt conductance G=RC/L, there is no distortion at the receiver end and the signal propagates at the speed of light. We show the feasibility and advantages of this shunt resistor scheme by a real design case of single-ended microstrip line in 0.10mum technology. The simulation results indicate we can achieve near perfect signaling of 10 Gbps data over a 10 mm serial link, yet no pre-emphasis/equalization or other special techniques are needed. Guidelines for determining the optimal value and spacing of the shunt resistors are also provided.
On the symmetric powers of cusp forms on GL(2) of icosahedral type

In this note we study the symmetric powers of strongly modular icosahedral representations $\rho$ of ${\rm Gal} (\bar{F}/F)$, $F$ a number field, and their twisted $L$--functions. We prove that for such $\rho$, there exists a cuspidal automorphic representation $\Pi = \Pi_{\infty} \otimes \Pi_{f}$ of $GL_{6} (\mathbb{A}_{F})$ such that $L (s, {\rm sym}^{5} (\rho)) = L (s, \Pi_{f})$. One sees that ${\rm sym}^{5} (\rho)$ is twist equivalent to $\rho' \otimes {\rm sym}^{2} (\rho)$ for another modular icosahedral representation $\rho'$, and our theorem is a special case of a cuspidality criterion formulated and proved in this paper, which may be of independent interest, for the Kim--Shahidi automorphic tensor product $\pi \boxtimes {\rm sym}^{2} (\pi')$, where $\pi$ and $\pi'$ are cuspidal automorphic representations of $GL (2) / F$. We also give a complete structure theory of modular icosahedral representations. As a result, we prove that $L (s, {\rm sym}^{m} (\rho) \otimes \chi)$ does not admit any Landau--Siegel zero when it is not divisible by $L$--functions of quadratic characters. In general, there is no such divisibility and and there are no Landau--Siegel zeros for such $L$--functions.
Anti-ulcer activity of the 9alpha-bromo analogue of Beclomethasone dipropionate against ethanol-induced gastric mucosal injury in rats.

The present study was performed to evaluate the anti-ulcer activity of the 9alpha-bromo analogue of Beclomethasone dipropionate against ethanol-induced gastric ulcer. Experimental groups were orally pre-treated with different doses of the 9alpha-bromo analogue of B. dipropionate in 10% Tween 20 solution. Ulcer control groups were pre-treated with vehicle solution and reference group was orally pre-treated with 20 mg/kg omeprazole. After one hour, all groups received absolute ethanol to generate gastric mucosal injury. After an additional hour, all rats were sacrificed and ulcer areas of gastric walls were determined. Grossly, ulcer control group exhibited severe mucosal injury, whereas pre-treatment with either omeprazole or the 9alpha-bromo analogue of B. dipropionate resulted in a significant decrease in acidity of gastric content, protection of gastric mucosal injury and increase in mucus production. Histological studies of gastric wall of ulcer control group revealed severe damage of gastric mucosa, along with edema and leucocyte infiltration of sub-mucosal layer compared to rats pre-treated with either omeprazole or 9alpha-bromo analogue of beclomethasone dipropionate. In conclusion, present finding suggests that the 9alpha-bromo analogue of B. dipropionate promotes ulcer protection as ascertained by the comparative decreases in ulcer areas, reduction of edema and leucocyte infiltration of the sub mucosal layer. Key words:
Temporal ASD 1 Brief Report : Impaired temporal reproduction performance in adults with Autism Spectrum Disorder

Although temporal processing has received little attention in the autism literature, there are a number of reasons to suspect that people with autism spectrum disorder (ASD) may have particular difficulties judging the passage of time. The present study tested a group of 20 high-functioning adults with ASD and 20 matched comparison participants on a temporal reproduction task. The ASD group made reproductions that were significantly further from the base durations than did the comparison group. They were also more variable in their responses. Furthermore the ASD group showed particular difficulties as the base durations increased, tending to underestimate to a much greater degree than the comparison group. These findings support earlier evidence that temporal processing is impaired in ASD.
Killing Me Softly—Future Challenges in Apoptosis Research

The induction of apoptosis, a highly regulated and clearly defined mode of cell dying, is a vital tenet of modern cancer therapy. In this review we focus on three aspects of apoptosis research which we believe are the most crucial and most exciting areas currently investigated and that will need to be better understood in order to enhance the efficacy of therapeutic measures. First, we discuss which target to select for cancer therapy and argue that not the cancer cell as such, but its interaction with the microenvironment is a more promising and genetically stable site of attack. Second, the complexity of combination therapy is elucidated using the PI3-K-mediated signaling network as a specific example. Here we show that the current clinical approach to sensitize malignancies to apoptosis by maximal, prolonged inhibition of so-called survival pathways can actually be counter productive. Third, we propose that under certain conditions which will need to be clearly defined in future, chronification of a tumor might be preferable to the attempt at a cure. Finally, we discuss further problems with utilizing apoptosis induction in cancer therapy and propose a novel potential therapeutic approach that combines the previously discussed features.
A comparison of exposure to risk factors for giardiasis in non-travellers, domestic travellers and international travellers in a Canadian community, 2006–2012

SUMMARY The purpose of this study is to determine how demographic and exposure factors related to giardiasis vary between travel and endemic cases. Exposure and demographic data were gathered by public health inspectors from giardiasis cases reported from the Region of Waterloo from 2006 to 2012. Logistic regression models were fit to assess differences in exposure to risk factors for giardiasis between international travel-related cases and Canadian acquired cases while controlling for age and sex. Multinomial regression models were also fit to assess the differences in risk profiles between international and domestic travel-related cases and endemic cases. Travel-related cases (both international and domestic) were more likely to go camping or kayaking, and consume untreated water compared to endemic cases. Domestic travel-related cases were more likely to visit a petting zoo or farm compared to endemic cases, and were more likely to swim in freshwater compared to endemic cases and international travel-related cases. International travellers were more likely to swim in an ocean compared to both domestic travel-related and endemic cases. These findings demonstrate that travel-related and endemic cases have different risk exposure profiles which should be considered for appropriately targeting health promotion campaigns.
The Effect of Gender, Ethnicity, and Income on College Students' Use of Communication Technologies

Because campus officials are relying on personal communication technologies to communicate with students, a question arises about access and usage. Although communication technologies are popular among college students, some evidence suggests that differences exist in ownership and use. We examined patterns of student ownership and use of cell phones and use of instant messaging, focusing on three predictors of digital inequality: gender, ethnicity, and income. Logistic and hierarchical linear regression analyses were used to analyze results from 4,491 students. The odds that female and white students owned cell phones were more than twice as high as for men and African-American students. Students in the $100,000-$149,000 per year income bracket were more than three times as likely to own a cell phone than those from the median bracket. However, being female, African-American, and/or from the highest income brackets was positively predictive of the number of text messages sent and the amount of time spent talking on a cell phone per week. We found no differences between students on the use of instant messaging. Implications of these results, as well as areas for further research, are provided.
Thyroid testing during pregnancy at an academic Boston Area Medical Center.

CONTEXT Gestational hypothyroidism leads to adverse obstetric outcomes and intellectual impairment in offspring. Pregnancy thyroid screening is controversial. OBJECTIVE Our objective was to determine thyroid function testing and thyroid dysfunction rates in pregnant women at Boston Medical Center (BMC). METHODS We retrospectively enrolled 1000 pregnant women aged 18-46 yr seen in BMC's Obstetrics/Gynecology (OB/GYN) or Family Medicine (FM) Clinics for their initial prenatal visit during 2008. Age, race, insurance, gestational age (GA), medical history (thyroid or other autoimmune disorders), obstetric history, and thyroid function tests were ascertained. RESULTS A total of 983 women were included (17 excluded for coding error). Median maternal age was 28 yr and GA 9.4 wk. Thyroid testing rates were similar in the 918 (93%) followed by OB/GYN and 65 (7%) followed by FM (84 vs. 86%). Thirty-nine women had previous thyroid disease, of whom 19 took thyroid medications. Four had type 1 diabetes, and nine had other autoimmune diseases. Serum TSH was obtained in 832 women (84.6%) at median GA 9.7 wk (range, 0.1-39.7). The majority were tested during their first trimester (65.5%). Of the 832 tested, 56 (6.7%) had trimester-specific elevated TSH, of whom nine had a previous history of thyroid disease, two had type 1 diabetes, and one had dyschromia. Based on current case-finding guidelines, 45 of 56 women (80.4%) with an elevated TSH in pregnancy might not have been tested. CONCLUSION BMC has a high rate of thyroid function testing in pregnancy. Targeted thyroid testing in only high-risk patients would have missed 80.4% of pregnant women with hypothyroidism.
Reliability Increase of Base Heating Prediction and Thermal Protection Methodology for Launch Vehicle Upper-Stage

During spacecraft missions in some countries all over the world, a number of failures have been observed that were due to the lower reliability of thermal protection of launch vehicles, so the reliability of base heating prediction and thermal protection is very important for successful emissions. The thermal protection of launch vehicles is usually carried out according to the base heating prediction. The base heating environment is a complicated combination of exhaust plume radiation, reversed plume flow convective heating, and engine nozzle radiation. In this paper, the numerical analysis of base heating is performed to improve the precision of the predictive analysis, and then the flow is modeled using a two–dimensional, Reynolds averaged, and compressible Naive-Stokes equations and DSMC for a chemically frozen mixture gas. After that, the radiation is modeled by using RMC. On the basis of this elaborate base heating prediction, the weaknesses of the thermal protection can be found and the elaborate thermal protection can be realized, so the reliability of base heating prediction and thermal protection methodology can be increased.