Miracle-dz/UniFAR-FTUs huggingface dataset:
Adolescent “Acting-Out” and Childhood History of Sexual Abuse

A questionnaire examining childhood history of sexual abuse and later (adolescent) behaviors was administered to a sample of 278 undergraduate women. Subjects with a history of sexual abuse were more likely than their nonabused peers to report “delinquent” teenage behaviors in four categories: school problems, conflict with authority, early sexual behavior, and eating problems. The functional aspects of such behaviors in abuse victims are explored, both in terms of escape from jeopardy and as a “cry for help. ” It is suggested that problem behaviors in adolescents be considered potential evidence of ongoing or previous abuse.
Genetical Genomics Analysis of a Yeast Segregant Population for Transcription Network Inference

Genetic analysis of gene expression in a segregating population, which is expression profiled and genotyped at DNA markers throughout the genome, can reveal regulatory networks of polymorphic genes. We propose an analysis strategy with several steps: (1) genome-wide QTL analysis of all expression profiles to identify eQTL confidence regions, followed by fine mapping of identified eQTL; (2) identification of regulatory candidate genes in each eQTL region; (3) correlation analysis of the expression profiles of the candidates in any eQTL region with the gene affected by the eQTL to reduce the number of candidates; (4) drawing directional links from retained regulatory candidate genes to genes affected by the eQTL and joining links to form networks; and (5) statistical validation and refinement of the inferred network structure. Here, we apply an initial implementation of this strategy to a segregating yeast population. In 65, 7, and 28% of the identified eQTL regions, a single candidate regulatory gene, no gene, or more than one gene was retained in step 3, respectively. Overall, 768 putative regulatory links were retained, 331 of which are the strongest candidate links, as they were retained in the expression correlation analysis and were located within or near an eQTL subregion identified by a multimarker analysis separating multiple linked QTL. One or several biological processes were statistically significantly overrepresented in independent network structures or in highly interconnected subnetworks. Most of the transcription factors found in the inferred network had a putative regulatory link to only one other gene or exhibited cis-regulation.
BK virus nephropathy in a heart transplant recipient: case report and review of the literature

Abstract: The human polyomavirus BK virus (BKV) remains latent in the urinary tract and may be reactivated in immunocompromised states. BKV is noted to be the etiologic agent of polyomavirus‐associated nephropathy (PVAN), which is a significant cause of allograft failure in renal transplant patients. Renal dysfunction following non‐renal solid organ transplantation is common and is typically attributed to drug toxicity or patient comorbidities. In this article we describe a case of PVAN in the native kidneys of a heart transplant recipient and review the literature. Although this is only the fourth case reported, BKV nephropathy should be considered in the differential diagnosis of new renal failure following non‐kidney solid organ transplantation, as early diagnosis of PVAN is necessary to prevent irreversible renal damage.
Numerical Simulation of Limit Cycles for Two Differential Polynomial Systems

Bifurcation of limit cycles for two differential polynomial systems is investigated using both qualitative analysis and numerical exploration. The investigation is based on detection functions which are particularly effective for the differential polynomial systems. The study reveals that each of the two systems has 8 limit cycles using detection function approach. By using method of numerical simulation, the distributed orderliness of these limit cycles is observed and their nicety places are determined. The study also indicates that each of these limit cycles passes the corresponding nicety point.
O Potencial Da Economia Da Cultura No Brasil (The Potential of Culture Economics in Brazil)

Portuguese Abstract: Desde a decada de noventa a cultura e vista, tambem, como um vetor de desenvolvimento de uma economia. “Economia da Cultura”, termo cada vez mais utilizado no debate economico atual, e uma nova e relevante fonte de desenvolvimento nas economias modernas por seu impacto em outros setores e sua grande capacidade de geracao de renda e emprego. Tendo isso em vista, o presente trabalho tem com objetivo estudar a importância do setor cultural na economia brasileira no ano de 2006. Para uma melhor delimitacao das atividades que compoe esse setor, o trabalho leva em consideracao os indicadores culturais do Instituto Brasileiro de Geografia e Estatistica (IBGE) e assim faz uso da metodologia de insumo-produto, a qual permite a compreender as relacoes desse setor com o restante da economia do Brasil.English Abstract: Since the nineties culture is seen also as a vector of development of an economy. "Cultural Economics," is a term that has been often used in the current economic debate, is a new and important source of development in modern economies because of its impact on other sectors and their great capacity for income generation and employment. With this in mind, this study has the objective to study the importance of the cultural sector in the Brazilian economy in 2006. For a better definition of the activities that make up this sector, the work takes into account the cultural indicators of the Brazilian Institute of Geography and Statistics (IBGE) and thus makes use of input-output methodology, which allows to understand the relationships of the sector with the rest of Brazil's economy.
Emotion Regulation in At-Risk Youth: The Influence of the Family Check-Up

The purpose of this study was to advance our understanding of the role of emotion regulation in the growth of conduct problems over time by examining whether increases in positive behavior support brought about by a family-centered intervention focusing on parenting were associated with more adaptive emotion regulation, and whether more adaptive emotion regulation at age 3 in turn mediated the association between improvements in positive behavior support from ages 2-3 and decreases in the growth of conduct problems from ages 2-4.The results indicated that emotion regulation at age 3 was significantly associated with growth in conduct problems from ages 2-4. However, neither the intervention nor positive behavior support was significantly associated with emotion regulation. Results provide support for the notion that emotion regulation plays an important role in the growth of conduct problems in early childhood, but do not support the hypotheses that a family-centered intervention would result in more adaptive child emotion regulation strategies or that such changes in emotion regulation would mediate previously reported intervention effects between parenting and reductions in growth of child conduct problems.
Design, Development and Testing of a Low-Cost sEMG System and Its Use in Recording Muscle Activity in Human Gait

Surface electromyography (sEMG) is an important measurement technique used in biomechanical, rehabilitation and sport environments. In this article the design, development and testing of a low-cost wearable sEMG system are described. The hardware architecture consists of a two-cascade small-sized bioamplifier with a total gain of 2,000 and band-pass of 3 to 500 Hz. The sampling frequency of the system is 1,000 Hz. Since real measured EMG signals are usually corrupted by various types of noises (motion artifacts, white noise and electromagnetic noise present at 50 Hz and higher harmonics), we have tested several denoising techniques, both on artificial and measured EMG signals. Results showed that a wavelet—based technique implementing Daubechies5 wavelet and soft sqtwolog thresholding is the most appropriate for EMG signals denoising. To test the system performance, EMG activities of six dominant muscles of ten healthy subjects during gait were measured (gluteus maximus, biceps femoris, sartorius, rectus femoris, tibialis anterior and medial gastrocnemius). The obtained EMG envelopes presented against the duration of gait cycle were compared favourably with the EMG data available in the literature, suggesting that the proposed system is suitable for a wide range of applications in biomechanics.
Colorectal cancer genomics: evidence for multiple genotypes which influence survival

Colorectal cancer (CRC) is a leading cause of cancer death and the mechanism for variable outcome in this disease is not yet fully understood. It is hypothesized that differences in the genetic make-up of tumours may be partially responsible for the differences observed in survival among same staged individuals for this disease. In this study the tumour genomes of 29 consecutive patients undergoing surgery for Dukes’ C CRC were assessed by comparative genomic hybridization (CGH). In addition, the CGH profiles from the tumours were compared with those from eight colorectal cell lines. Great variation in genetic grade (all detectable aberrations i.e., loss + gain) was observed in 29 Dukes’ C colorectal tumours by CGH (median four aberrations per tumour, range 0–20). Gain was found in 76% and loss in 41% of tumours. The most frequently observed regions of gain were 13q (27.6%), 20q (27.6%), 7p (24.1%), 8q (24.1%), and 1q (20.7%) and loss were 18q (31%), 4q (20.7%), 17p (20.7%), 18p (20.7%), and 15q (20.1%). None of these specific genomic aberrations were associated with patient survival. However, patients with more than two aberrations had a better survival than patients with fewer regions of loss and gain (P = 0.02). CRC cell lines had similar regions of loss or gain as the tumours. However, the frequency of genomic aberrations was much greater in the CRC cell lines. Although genomic change in CRC is relevant to the survival of patients with Dukes’ C CRC, careful analysis is required to identify cell lines which are representative models of CRC genomics. © 2001 Cancer Research Campaign http://www.bjcancer. com
Adapted SIFT Descriptor for Improved Near Duplicate Retrieval

The scale invariant feature transformation algorithm (SIFT) has been designed to detect and characterize local features in images. It is widely used to find similar regions in affine transformed images, to recognize similar objects or to retrieve near-duplicates of images. Due to the computational complexity of SIFT based matching operations several approaches have been proposed to speed up this process. However, most approaches lack significant decrease of matching accuracy compared to the original descriptor. We propose an approach that is optimized for near-duplicate image retrieval tasks by a dimensionality reduction process that differs from other methods by preserving the information around the keypoints of any region patches of the original descriptor. The computation of the proposed Region Compressed (RC) SIFTâ64D descriptors is therefore faster and requires less memory for indexing. Most important, the obtained features show at the same time a better retrieval performance and seem to be even more robust. In order to prove this, we provide results of a comparative performance analysis using the original SIFTâ128D, reduced SIFT versions, SURFâ64D and the proposed RC-SIFTâ64D in image near-duplicate retrieval using large scale image benchmark databases.
Age and Total Ribavirin Dose are Independent Predictors of Relapse after Interferon Therapy in Chronic Hepatitis C Revealed by Data Mining Analysis

Background This study aimed to define factors associated with relapse among responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in chronic hepatitis C. Methods A cohort of genotype 1b chronic hepatitis C patients treated with PEG-IFN plus RBV and who had an undetectable HCV RNA by week 12 (n=951) were randomly assigned to model derivation (n=636) or internal validation (n=315) groups. An independent cohort (n=598) were used for an external validation. A decision tree model for relapse was explored using data mining analysis. Results The data mining analysis defined five subgroups of patients with variable rates of relapse ranging from 13% to 52%. The reproducibility of the model was confirmed by internal and external validations (r2=0.79 and 0.83, respectively). Patients with undetectable HCV RNA at week 4 had the lowest risk of relapse (13%), followed by patients <60 years with undetectable HCV RNA at week 5–12 who received ≥3.0 g/kg of body weight of RBV (16%). Older patients with a total RBV dose <3.0 g/ kg had the highest risk of relapse (52%). Higher RBV dose beyond 3.0 g/kg was associated with further decrease of relapse rate among patients <60 years (up to 11%) but not among older patients whose relapse rate remained stable around 30%. Conclusions Data mining analysis revealed that time to HCV RNA negativity, age and total RBV dose was associated with relapse. To prevent relapse, ≥3.0 g/kg of RBV should be administered. Higher dose of RBV may be beneficial in patients <60 years.
On the Comparison of Intersystem Interference Scenarios Between IMT-Advanced and Fixed Services Over Various Deployment Areas at 3500 MHz

ONTHECOMPARISONOFINTERSYSTEMINTERFERENCESCENARIOSBETWEENIMT-ADVANCEDANDFIXEDSERVICESOVERVARIOUSDEPLOYMENTAREASAT3500MHzZ.A. ShamsanandT.A. RahmanWirelessCommunicationCenterFacultyofElectricalEngineeringUniversitiTeknologiMalaysia(UTM)MalaysiaAbstract—At WRC-07, the frequency band 3500MHz has beenallotted for the next generation of mobile International MobileTelecommunication-Advanced (IMT-Advanced). Meanwhile thisband is already in used by ﬁxed services, which means thatharmful interference probability may be transpired. In this paper,the coexistence between the two services in various geographicaldeployment areas (dense urban, urban, suburban, and rural areas)willbeanalyzed. Spectrumemissionmaskisaneﬀectiveinterferencemodel will be invested and interference to noise ratio of
Predicting Planets in Known Extrasolar Planetary Systems. I. Test Particle Simulations

Recent work has suggested that many planetary systems lie near instability. If all systems are near instability, then at least one additional planet must exist in stable regions of well-separated extrasolar planetary systems to push these systems to the edge of stability. We examine the known systems by placing massless test particles in between the planets and integrating for 1-10 million yr. We find that some systems, HD 168443 and HD 74156, eject nearly all test particles within 2 million yr. However, we find that HD 37124, HD 38529, and 55 Cnc have large contiguous regions in which particles survive for 10 million yr. These three systems, therefore, seem the most likely candidates for additional companions. Furthermore, HD 74156 and HD 168443 must be complete; therefore radial velocity surveys should only focus on detecting more distant companions. We also find that several systems show stable regions that only exist at nonzero eccentricities.
Implementing a Semantic Interpreter Using Conceptual Graphs

A parser applies grammar rules to generate a parse tree that shows the syntactic structure of a sentence. This paper describes a semantic interpreter that starts with a parse tree and generates conceptual graphs that represent the meaning of the sentence. To generate conceptual graphs, the interpreter joins canonical graphs associated with each word of input. The result is a larger graph that represents the entire sentence. During the interpretation, the parse tree serves as a guide to show how the graphs are joined. Both the front-end parser and the back-end semantic interpreter are written in the Programming Language for Natural Language Processing (PLNLP).
Impact of Different Carbapenems and Regimens of Administration on Resistance Emergence for Three Isogenic Pseudomonas aeruginosa Strains with Differing Mechanisms of Resistance

ABSTRACT We compared drugs (imipenem and doripenem), doses (500 mg and 1 g), and infusion times (0.5 and 1.0 [imipenem], 1.0 and 4.0 h [doripenem]) in our hollow-fiber model, examining cell kill and resistance suppression for three isogenic strains of Pseudomonas aeruginosa PAO1. The experiments ran for 10 days. Serial samples were taken for total organism and resistant subpopulation counts. Drug concentrations were determined by high-pressure liquid chromatography-tandem mass spectrometry (LC/MS/MS). Free time above the MIC (time > MIC) was calculated using ADAPT II. Time to resistance emergence was examined with Cox modeling. Cell kill and resistance emergence differences were explained, in the main, by differences in potency (MIC) between doripenem and imipenem. Prolonged infusion increased free drug time > MIC and improved cell kill. For resistance suppression, the 1-g, 4-h infusion was able to completely suppress resistance for the full period of observation for the wild-type isolate. For the mutants, control was ultimately lost, but in all cases, this was the best regimen. Doripenem gave longer free time > MIC than imipenem and, therefore, better cell kill and resistance suppression. For the wild-type organism, the 1-g, 4-h infusion regimen is preferred. For organisms with resistance mutations, larger doses or addition of a second drug should be studied.
Distribution of ventilation/perfusion ratios in pulmonary embolism: an adjunct to the interpretation of ventilation/perfusion lung scans.

UNLABELLED Diagnosis of pulmonary embolism (PE) by visual interpretation of ventilation/perfusion (V/Q) scans is limited by the high percentages of patients classified in the intermediate- and low-probability categories. This study proposes a quantitative analysis of the distribution of V/Q ratios to better identify patients with PE. METHODS We studied 99 consecutive patients who underwent dual-isotope (81m)Kr/(99m)Tc-macroaggregate V/Q scanning and arterial blood gas analysis within 48 h. The 8-view V/Q scans were visually analyzed by 2 observers according to the revised criteria of the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) (normal scan or low, intermediate, or high probability of PE). Quantitative analysis of the posterior-view distribution histogram of V/Q ratios was performed using dedicated software. Briefly, regions of interest were drawn around the lungs on the matched V/Q images, smooth filtering was applied, normalized regional V/Q ratios were calculated within each pixel, and a distribution histogram was built. RESULTS Patients with normal scans (n = 16) had a predominance of V/Q ratios (63.3% +/- 13.0%) between 0.8 and 1.2. They had only 9.8% +/- 5.8% of ratios > 1.2, and the remaining 26.9% +/- 7.5% of ratios were <0.8. By contrast, patients with PE (n = 34) were characterized by a significant increase (15.5 +/- 10.0%, P = 0.04) in high V/Q ratios (>1.2) and a significant increase (34.5% +/- 8.2%, P = 0.003) in low V/Q ratios (<0.8). Interestingly, a similar pattern was found in patients with a high PIOPED probability of PE, 21.3% +/- 11.0% and 37.5% +/- 9.2%, respectively. Within the nondiagnostic group (intermediate- + low-probability scans, n = 58), 17 patients were finally diagnosed with PE. Analysis of the distribution histogram in this group allowed the identification of 5 patients with PE (specificity, 78%). CONCLUSION A quantitative approach to lung scan interpretation, based on the distribution histogram of V/Q ratios, may be helpful for categorizing patients with suspected PE.
Model‐based design of chemotherapeutic regimens that account for heterogeneity in leucopoenia

Patients treated with multicycle chemotherapy can exhibit large interindividual heterogeneity of haematotoxicity. We describe how a biomathematical model of human granulopoiesis can be used to design risk‐adapted dose‐dense chemotherapies, leading to more similar leucopoenias in the population. Calculations were performed on a large data set for cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP)‐like chemotherapies for aggressive non‐Hodgkin lymphoma. Age, gender, Eastern Cooperative Oncology Group performance status, lactate dehydrogenase and the degree of leucopoenia within the first therapy cycle were used to stratify patients into groups with different expected severity of leucopoenia. We estimated risk‐specific bone marrow toxicities depending on the drug doses administered. These toxicities were used to derive risk‐adapted therapy schedules. We determined different doses of cyclophosphamide and additional etoposide for patients treated with CHOP‐14. Alternatively, the model predicted that further reductions of cycle duration were feasible in groups with low toxicity. We also used the model to identify appropriate granulocyte colony‐stimulating factor (G‐CSF) schedules. In conclusion, we present a method to estimate the potential of risk‐specific dose adaptation of different cytotoxic drugs in order to design chemotherapy protocols that result in decreased diversity of leucopoenia between patients, to develop dose‐escalation strategies in cases of low leucopoenic reaction and to determine optimal G‐CSF support.
Portal and gastric mucosal hemodynamics in cirrhotic patients with portal‐hypertensive gastropathy

Controversy exists as to the nature of gastric perfusion in portal‐hypertensive gastropathy. To investigate portal hemodynamics and gastric mucosal perfusion in cirrhotic patients with and without portalhypertensive gastropathy, we subjected 56 cirrhotic patients with portal hypertension to portal vein catheterization, pneumatic pressure sensor technique, duplex sonography and laser Doppler flowmetry. Thirteen patients had portal‐hypertensive gastropathy: In 10 it was mild, and in 3 it was severe. The presence of portal‐hypertensive gastropathy seemed to be independent of age, sex, cause of cirrhosis or grade of esophageal varices. Portal venous pressure, esophageal variceal pressure, portal venous flow and congestion index in patients with portal‐hypertensive gastropathy were not significantly different from the values in those without portal‐hypertensive gastropathy. However, portal‐variceal pressure gradient (subtracting esophageal variceal pressure from portal venous pressure) (p < 0.01) and the incidence of palisading‐type esophageal varices on portography (p < 0.05) was increased in patients with portalhypertensive gastropathy significantly more than in those without portal‐hypertensive gastropathy. In the fundus, gastric mucosal blood flow was significantly higher in patients with portal‐hypertensive gastropathy than in those without portal‐hypertensive gastropathy, whereas in the corpus and the antrum the values were not significantly different. We suggest that the mucosa of the upper stomach in patients with portal‐hypertensive gastropathy is congestive and highly perfused. The pathogenesis of portal‐hypertensive gastropathy may be related to both congestion and hyperemia in the upper stomach. (Hepatology 1994;20:1432–1436).
Selected temperamental properties and achievement motivation of fencers.

The goal of this study was to characterize the temperamental properties (i.e. reactivity, mobility of nervous processes, the strength of the braking process) and achievement motivation of competitive fencers, inclusive of defining interconnections between these variables. 116 competitive fencers aged 14 to 32 participated in the study (41 of whom have been members of a select national team in their age groups). It has been found that the subjects were marked by a relatively low level of reactivity, a high level of mobility of nervous processes, a comparatively high level of strength of the braking process and an average level of achievement motivation. The statistical analysis also revealed that a low reactivity and a high level of mobility of nervous processes of fencers favored a high achievement motivation. The conclusions drawn from this study allow us to formulate the practical recommendations related to the fencer’s training process that were also presented in this survey.