Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Incorporation of Oat Flour on Nutritional and Organoleptic Characteristics of Bread and Noodles

Oat (Avena sativa L.) is an underutilized cereal and is considered as a rich source of protein, minerals, lipids, β-glucan and other phytochemicals. It has an immense scope for its application in preparation of various nutraceutical and functional foods. Oat flour was incorporated with wheat flour at different concentrations for preparation of breads and noodles. Breads were prepared by incorporation of oat flour (OF) in wheat flour (WF) at different levels (0, 10, 15, 20 and 25%). Overall acceptability of breads decreased with increase in level of oat flour. However, breads were moderately desirable up to 20% replacement of WF with OF and slightly desirable at 25% level of replacement. Significant decrease in loaf volume of oat incorporated bread (OIB) was observed with increase in level of incorporation of OF in WF. Oat incorporated noodles (OIN) were prepared by substitution of OF in WF at proportion of 0, 10, 20, 30 and 40%. These were moderately desirable only up to 30% replacement of wheat flour with oat flour and slightly desirable thereafter. There was significant (P≤0.05) increase in proteins, crude fibres, ash and fat content but significant decrease in carbohydrate content and calorific value of processed products was recorded with increased incorporation of OF in WF. Results of organoleptic evaluation concluded that bread and noodles were moderately desirable up to 20 and 30% replacement of wheat flour with oat flour, respectively. Therefore, oat can be successfully substituted with wheat flour upto a level of 20% for bread and 30% for noodle preparation thereby, enhancing the nutritional components such as crude protein, fibre, fat and ash content in prepared products. Current research in Nutrition and Food science Journal Website:www.foodandnutritionjournal. org ISSN: 2347-467X, Vol. 06, No. (1) 2018, Pg. 148-156 CONTaCT Krishan Kumar krishankumar02007@gmail.com Department of Food Technology, Akal College of Agriculture, Eternal University, Baru Sahib, Sirmour, India. © 2018 The Author(s). Published by Enviro Research Publishers This is an Open Access article licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/ ), which permits unrestricted NonCommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. To link to this article: http://dx.doi. org/10.12944/CRNFSJ.6. 1.17 article history Received: 19 December 2017 Accepted: 10 April 2018
Collagen Accumulation in Osteosarcoma Cells lacking GLT25D1 Collagen Galactosyltransferase*

Collagen is post-translationally modified by prolyl and lysyl hydroxylation and subsequently by glycosylation of hydroxylysine. Despite the widespread occurrence of the glycan structure Glc(α1–2)Gal linked to hydroxylysine in animals, the functional significance of collagen glycosylation remains elusive. To address the role of glycosylation in collagen expression, folding, and secretion, we used the CRISPR/Cas9 system to inactivate the collagen galactosyltransferase GLT25D1 and GLT25D2 genes in osteosarcoma cells. Loss of GLT25D1 led to increased expression and intracellular accumulation of collagen type I, whereas loss of GLT25D2 had no effect on collagen secretion. Inactivation of the GLT25D1 gene resulted in a compensatory induction of GLT25D2 expression. Loss of GLT25D1 decreased collagen glycosylation by up to 60% but did not alter collagen folding and thermal stability. Whereas cells harboring individually inactivated GLT25D1 and GLT25D2 genes could be recovered and maintained in culture, cell clones with simultaneously inactive GLT25D1 and GLT25D2 genes could be not grown and studied, suggesting that a complete loss of collagen glycosylation impairs osteosarcoma cell proliferation and viability.
Antioxidant activity of free and bound compounds in quinoa (Chenopodium quinoa Willd.) seeds in comparison with durum wheat and emmer.

UNLABELLED Antioxidant activity (AA) of quinoa (Chenopodium quinoa Willd.) seeds, as well as of durum wheat (Triticum turgidum L. ssp. durum Desf.) and of emmer (T. turgidum L. ssp. dicoccum Schübler) grains, was evaluated by studying hydrophilic (H), lipophilic (L), free-soluble (FSP) and insoluble-bound (IBP) phenolic extracts using the new lipoxygenase/4-nitroso-N,N-dimethylaniline (LOX/RNO) method, able to simultaneously detect different antioxidant mechanisms, as well as using the Oxygen Radical Absorbance Capacity (ORAC) and the Trolox Equivalent Antioxidant Capacity (TEAC) assays, which measure the scavenging activity against peroxyl and ABTS [2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonate)] radicals, respectively. The species under study were compared with respect to the sum of AA values of H, L and FSP extracts (AA(H+L+FSP)), containing freely solvent-soluble antioxidants, and AA values of IBP extracts (AA(IBP)), representing the phenolic fraction ester-linked to insoluble cell wall polymers. The LOX/RNO and ORAC methods measured in quinoa flour a remarkable AA(H+L+FSP) higher than durum wheat, although lower than emmer; according to the same assays, the IBP component of quinoa resulted less active than the durum wheat and emmer ones. The TEAC protocol also revealed a high AA(H+L+FSP) for quinoa. Interestingly, the ratio AA(H+L+FSP)/AA(H+L+FSP+IBP), as evaluated by the LOX/RNO and ORAC assays, resulted in quinoa higher than that of both durum wheat and emmer, and much higher than durum wheat, according to the TEAC protocol. This may suggest that antioxidants from quinoa seeds may be more readily accessible with respect to that of both the examined wheat species. PRACTICAL APPLICATIONS Quinoa seeds may represent an excellent source of natural antioxidant compounds and, in particular, of the free-soluble antioxidant fraction. These compounds may improve nutritive and health-beneficial properties of quinoa-based gluten-free products, thus expanding interest for quinoa utilization from celiac patients to the general population.
Homelessness and housing crises among individuals accessing services within a Canadian emergency department.

ACCESSIBLE SUMMARY Studies have indicated that individuals who are homeless access hospital emergency departments more frequently and may have different needs than individuals who are housed. Successful interventions have been developed and tested to reduce discharge to homelessness for psychiatric inpatients but have not been similarly tested for discharge from emergency departments. This study was developed to provide baseline data on this issue to inform future emergency department interventions. Findings from the current study suggest that discharge from emergency departments to homelessness happens frequently in London, Canada. Participants are unlikely to spontaneously disclose their housing/homelessness issue when first entering the emergency department, which may result in services that do not adequately meet their complex needs. Screening for housing issues is necessary within emergency departments and psychiatric crisis teams as housing issues may be a reason for accessing care or contribute to the presenting condition. Nurses are in an ideal position to evaluate housing needs among emergency department patients. Services outside of the emergency department are also needed to address housing issues, particularly outside of regular office hours. ABSTRACT Individuals who have mental health issues and are homeless or in housing crisis have been found to access emergency departments more frequently than individuals with stable housing. While emergency departments primarily focus on medical issues, homeless individuals may require psychosocial support as well. This study examined issues around housing crises and emergency department use for individuals with mental illness in Canada. Collecting baseline data about these issues is important to inform subsequent interventions. Administrative data from a hospital emergency department and psychiatric crisis service were collected, and five individuals accessing the emergency department for psychiatric reasons were interviewed. Results indicated that individuals with an identified housing crisis accessed the emergency department 930 times in 6 months. None of the interview participants identified housing as the primary reason for accessing the emergency department, but all noted that housing was a contributing stressor. Future research is needed to examine ways in which discharge to homelessness from emergency departments can be avoided and identify alternative services to address housing concerns, particularly for individuals with mental illness. Crisis service and emergency department staff, especially nurses, can play an important role in screening for housing issues and connecting individuals to outside services.
A Resolution-Based Decision Procedure for Extensions of K4

This paper presents a resolution decision procedure for transitive propositional modal logics. The procedure combines the relational translation method with an ordered chaining calculus designed to avoid unnecessary inferences with transitive relations. We show the logics K4, KD4 and S4 can be transformed into a bounded class of well-structured clauses closed under ordered resolution and negative chaining. Area: Computational aspects of modal logic
Fundamental parameters and abundances of metal-poor stars : the SDSS standard BD +17 4708

The atmospheric parameters and iron abundance of the Sloan Digital Sky Survey (SDSS) spectrophotometric standard star BD +17 4708 are critically examined using up-to-date Kurucz model atmospheres, LTE line formation calculations, and reliable atomic data. We find $T_{{\rm eff}}=6141$ ± 50 K, $\log g=3.87$ ± 0.08, and ${\rm [Fe/H]}=-1.74$ ± 0.09. The line-of-sight interstellar reddening, bolometric flux, limb-darkened angular diameter, stellar mass, and the abundances of Mg, Si, and Ca are also obtained: $E(B-V)=0.010$ ± 0.003, $f_{{\rm bol}}=(4.89\pm0.10)$ $\times$ 10 -9 erg cm -2 s -1 , $\theta=0.1016$ ± 0.0023 mas, $M=0.91$ ± $0.06~M_\odot$, ${\rm [Mg/Fe]}=0.40$ ± 0.10, ${\rm [Si/Fe]}=0.35$ ± 0.11, ${\rm [Ca/Fe]}=0.36$ ± 0.11. This star is a unique example of a moderately metal-poor star for which the effective temperature ($T_{{\rm eff}}$) can be accurately constrained from the observed spectral energy distribution (corrected for reddening). Such analysis leads to a value that is higher than most spectroscopic results previously reported in the literature (~5950 K). Interstellar reddening was estimated using various prescriptions, including an analysis of interstellar lines. The surface gravity of the star was inferred from the fitting of the wings of the $\ion{Mg}{i}$ b lines. We used transition probabilities measured in the laboratory and reliable damping constants for unblended Fe lines to derive the iron abundance using both $\ion{Fe}{i}$ and $\ion{Fe}{ii}$ lines. We find that the ionization balance of Fe lines is satisfied only if a low $T_{{\rm eff}}$ (~5950 K) is adopted. The mean iron abundance we obtain from the $\ion{Fe}{ii}$ lines corresponds to $A_{\rm Fe}=5.77$ ± 0.09 (${\rm [Fe/H]}=-1.74$ for our derived $A_{{\rm Fe},\odot}=7.51$) while that from the $\ion{Fe}{i}$ lines is $A_{\rm Fe}=5.92$ ± 0.11, and therefore with our preferred $T_{{\rm eff}}$ (6141 K), the discrepancy between the mean iron abundance from $\ion{Fe}{i}$ and $\ion{Fe}{ii}$ lines cannot be explained by overionization by UV photons as the main non-LTE effect. Interestingly, the $\ion{Fe}{i}$ excitation balance is satisfied with a $T_{{\rm eff}}$ only slightly warmer than our preferred solution and not with the lower value of 5950 K. We also comment on non-LTE effects and the importance of inelastic collisions with neutral H atoms in the determination of oxygen abundances in metal-poor stars from the 7774 A $\ion{O}{i}$ triplet.
Micro mobile MPLS: a new scheme for micro-mobility management in 3G all-IP networks

This article presents the micro mobile MPLS scheme, which is a new proposal for IP local mobility in wireless MPLS access networks. Our proposal is based on multiprotocol label switching (MPLS) and mobile IP and relies on two-level hierarchy architecture. With micro mobile MPLS, mobile nodes (MNs) do not require changes to their IP protocol stack, neither for micro-mobility nor macro-mobility. Nevertheless, it still uses Mobile IP for macro-mobility scenarios. The main features of our scheme are related on scalability, flexibility, fast handoff and the ability to provide quality of service (QoS) by using the underlying MPLS traffic engineered paths. Simulation results are given to justify the benefits of our proposed architecture.
Erbium Oxide as new Saturable Absorber for Short-Pulse Generation at 1.55-micron region

This paper reported on demonstration of Q-switched erbium doped fiber laser (EDFL) by incorporating erbium oxide (Er2O3) film as a saturable absorber (SA). The EDFL was constructed in ring cavity formation, where the Q-switching operation performances are capture out from 10 % port of 10 dB coupler. A stable Q-switched laser obtained at 1564 nm peak wavelength with a repetition rate from 72 kHz to 109 kHz, which corresponds to the pump power trend. Looking into this preliminary finding, the Er2O3 film has a potential to be utilized as an SA for short pulsed fiber laser generation.
Quality pneumonia care: distinguishing community-acquired from health care-associated pneumonia.

PURPOSE Differences in the definition, demographics, risk factors, etiology, and treatment for health care-associated pneumonia (HCAP) versus community-acquired pneumonia (CAP) are discussed. SUMMARY Health care-associated infections (HCAI) represent a population of outpatients with exposure to health care institutions and procedures who develop nosocomial-like infections. HCAI are etiologically similar to nosocomial infections with gram-negative organisms, methicillin-resistant Staphylococcus aureus (MRSA), and multidrug-resistant (MDR) pathogens predominating. These patients are ambulatory, community residents who often present to hospital emergency departments as would patients with community-acquired infection. Although many differences between HCAI and community-acquired infections, as well as HCAP and CAP, remain to be elucidated, the emerging evidence has identified multiple and important differences. Because of etiologic differences between CAP and HCAP, treatment strategies necessarily differ. Mistaking HCAP for CAP may result in the use of inappropriate empirical therapy, which is an established source of treatment failure, morbidity, and mortality. Thus, it is essential for physicians to be capable of recognizing risk factors for HCAI and HCAP as well as competently select and implement appropriate treatment strategies. CONCLUSION The etiologic differences between HCAP and CAP require different treatment strategies. No clinical or demographic characteristics nor signs and symptoms distinguish HCAP from CAP. Rather, physicians must rely on a thorough and careful history of each patient as well as their own clinical judgment.
EM Cygni: A study of its eclipse timings

EM Cygni is a Z Cam-subtype eclipsing dwarf nova. Its orbital period variations were reported in the past but the results were in conflict to each other while other studies allowed the possibility of no period variation. In this study we report accurate new times of minima of this eclipsing binary and update itsO –C diagram.We also estimate the mass transfer rate in EM Cygni system and conclude that the mass transfer is far from the critical value. The mass transfer rate determined from the eclipse timings is in agreement with the spectroscopically determined value. (© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
The effect of incentive spirometry on arterial blood gases after coronary artery bypass surgery (CABG)

Background: After coronary artery bypass surgery, pulmonary complications and oxygenation disorders are common, which have an important role in mortality and morbidity. Different methods are used for the improvement of pulmonary function and oxygenation, of which incentive spirometry (IS) has been investigated here. The aim of this study is to evaluate the effects of IS on arterial blood gases after coronary artery bypass graft (CABG). Materials and Methods: This was a clinical trial. Fifty patients who were candidates for CABG were chosen. The patients had been allocated to two random groups of intervention and control. The intervention was done through IS. These two groups were compared for the arterial blood gases' preoperative level, and the levels on first (after extubation), second, and third postoperative days. Results: The study findings showed that on the third postoperative day, there was a significant difference between the intervention and control groups in the mean amount of arterial blood oxygen (82.3 ± 4.7 vs. 72.7 ± 7.1, respectively, P = 0.02), arterial blood carbon dioxide (36.8 ± 2 vs. 43.7 ± 3.2, respectively, P = 0.007), and oxygen saturation (96.8 ± 1.4 vs. 90.5 ± 1.4, respectively, P = 0.03). Conclusions: This investigation shows that using IS is significantly effective in the improvement of blood arterial gas parameters.
Graphene Oxide/Multilayer-Graphene Synthesized from Electrochemically Exfoliated Graphite and Its Influence on Mechanical Behavior of Polyurethane Composites

Graphene Oxide/Multilayer-Graphene (GO-MG) flakes were obtained using an electrochemically exfoliated graphite (GR) electrode from secondary steel-making industry performed in a two-electrode system using tungsten as the counter electrode and GR as the working electrode. The exfoliated GO-MG flakes were processed and incorporated in an elastomeric polyurethane (PU) matrix. The mechanical properties of the PU/GO-MG composites were evaluated and compared with equivalent composites made of PU/GR powder. From experimental data analysis it was concluded that GO-MG flakes were approximately composed of 67 wt% GO and 33 wt% MG. The number of layers in the graphene flakes was estimated to be between 2 and 5 sheets. PU showed a breaking stress of 570 kPa, while the PU/20wt% GR attained a maximum stress of 750 kPa as compared to PU/10wt% GO-MF composite exhibiting a breaking stress of 1060 kPa.
A comparison between the oxidation with laccase and horseradish peroxidase for triclosan conversion

Triclosan is a broad-spectrum biocide used in personal-care products that is suspected to be linked to the emergence of antibiotic-resistant bacteria. In the present work, the enzymes horseradish peroxidase and laccase from Trametes versicolor were evaluated for the conversion of triclosan in an aqueous matrix. The removal of antibacterial activity by the enzymatic processes was evaluated by an assay based on the growth inhibition of Escherichia coli K12. The horseradish peroxidase (HRP) process appears more advantageous than the laccase process in removing triclosan from an aqueous matrix, considering the reaction parameters pH, temperature, catalytic efficiency, and enzyme concentration. The highest conversion of triclosan catalysed by laccase was observed at pH 5.0, that is, lower than the typical pH range (6.5–7.5) of sewage treatment plants' effluents. The efficiency of laccase process was much more impacted by variations in the temperature in the range of 10–40°C. Kinetic studies showed that triclosan is a substrate more specific for HRP than for laccase. The protein content for the HRP-catalysed process was 14 times lower than that for the laccase process. Decay kinetics suggest that reaction mechanisms depend on enzyme concentration and its concentration. Both processes were able to reduce the antibacterial activity, and the residual activity of the treated solution is probably due to non-converted triclosan and not due to the reaction products. The laccase-catalysed conversion of triclosan in an environmental relevant concentration required a higher amount of enzyme than that required in the HRP process.
Another Way to Find the Nearest Neighbor in Growth-Restricted Metrics

In this paper, we give sequential and distributed dynamic data structures for finding nearest neighbors in certain growth restricted metrics. In particular, we give a sequential data structure that uses linear space, and requires O(log n) expected time and O(log n) time for lookups with high probability. This improved the results of Karger and Ruhl, whose data structure takes O(n log n) space with comparable expected time bounds. Also, we describe a dynamic, load-balanced data structure using O(log n) space per node, matching the bound of Karger and Ruhl. We note that our algorithm is significantly different in structure from those of Karger and Ruhl [4], and perhaps substantially simpler. It is based on a technique used for object location developed by Plaxton, Rajaraman and Richa in [7], which gives it an application to peer-to-peer networks.
MRI depiction and 3D visualization of three anterior cruciate ligament bundles

The anterior cruciate ligament (ACL) is divided into three fiber bundles (AM‐M: anteromedial‐medial, AM‐L: anteromedial‐lateral, PL: posterolateral). We attempted to depict the three bundles of the human ACL on MRI images and to obtain 3‐dimensional visualization of them. Twenty‐four knees of healthy volunteers (14 males, 10 females) were scanned by 3T‐MRI using the fat suppression 3D coherent oscillatory state acquisition for the manipulation of imaging contrast (FS 3D‐COSMIC). The scanned images were reconstructed after the isotropic voxel data, which allows the images to be reconstructed in any plane, was acquired. We conducted statistical examination on the identification rate of the three ACL bundles by 2D planes. Segmentation and 3D visualization of the fiber bundles using volume rendering were performed. The triple‐bundle ACL was best depicted in the oblique axial plane. While the AM‐M and AM‐L bundles were clearly depicted in all cases, the PL bundle was not clearly visualized in two knees (8%). Therefore, the three ACL bundles were depicted in 22 knees (92%). The results of 3D visualization of the fiber arrangement agreed well with macroscopic findings of previous anatomical studies. 3T‐MRI and the isotropic voxel data from FS 3D‐COSMIC made it possible to demonstrate the identifiable depiction of three ACL bundles in nearly all cases. 3D visualization of the bundles could be a useful tool to understand the ACL fiber arrangement. Clin. Anat. 30:276–283, 2017. 2016 The Authors. Clinical Anatomy published by Wiley Periodicals, Inc. on behalf of American Association of Clinical Anatomists.
Post-catheterisation arterial thrombosis in children – pathophysiology, prevention, and treatment

Abstract Lower limb ischaemia is the most frequent complication of cardiac catheterisation in children. It is often overlooked, but it can cause significant disability and may limit arterial access sites to repeat diagnostic or interventional catheterisations. A narrative review of the literature on arterial access site thrombosis in children was carried out with a special focus on current evidence that supports preventive and treatment strategies. Anticoagulation, thrombolysis, and thrombectomy have been used successfully to treat arterial access site thrombosis. However, it is not completely established which is the role of each treatment modality and what is the most appropriate timing to deliver it. Therefore, diagnostic and therapeutic strategies have to be prospectively investigated, particularly for clarifying the role of new pharmacologic interventions and of percutaneous and surgical thrombectomy in the current era.