Miracle-dz/UniFAR-FTUs huggingface dataset:
HEGEMONIC AND MINORITY DISCOURSES AROUND IMMIGRANTS: A CORPUS-BASED CRITICAL DISCOURSE ANALYSIS

This study aims to analyse discourses surrounding the word immigrants in a large collection of naturally occurring language, ‘ukWac’ corpus (Web as Corpus). It employs corpus linguistics as a methodology to carry out critical discourse analysis research. Specifically, collocation analyses were used to identify dominant representations and discourse prosodies (Stubbs, 2007) of immigrants. Concordance analyses were then applied to examine the data in a more qualitative way. The findings suggest that while there are a few instances indicating positive representations of immigrants, hegemonic discourses around them are more negative. They are predominantly constructed as illegal entities, victims and dangerous groups. These constructions are likely to prime people to think that all immigrants are illegal and threatening, and will not be able to integrate into their host society.
Preprocedural ultrasound examination versus manual palpation for thoracic epidural catheter insertion

Background and Aims: Ultrasound imaging before neuraxial blocks was reported to improve the ease of insertion and minimize the traumatic trials. However, the data about the use of ultrasound in thoracic epidural block are scanty. In this study, pre-insertion ultrasound scanning was compared to traditional manual palpation technique for insertion of the thoracic epidural catheter in abdominal operations. Subjects and Methods: Forty-eight patients scheduled to midline laparotomy under combined general anesthesia with thoracic epidural analgesia were included in the study. Patients were divided into two groups with regard to technique of epidural catheter insertion; ultrasound group (done ultrasound screening to determine the needle insertion point, angle of insertion, and depth of epidural space) and manual palpation group (used the traditional manual palpation technique). Number of puncture attempts, number of puncture levels, and number of needle redirection attempts were reported. Time of catheter insertion and complications were also reported in both groups. Results: Ultrasound group showed lower number of puncture attempts (1 [1, 1.25] vs. 1.5 [1, 2.75], P = 0.008), puncture levels (1 (1, 1) vs. 1 [1, 2], P = 0.002), and needle redirection attempts (0 [0, 2.25] vs. 3.5 [2, 5], P = 0.00). Ultrasound-guided group showed shorter time for catheter insertion compared to manual palpation group (140 ± 24 s vs. 213 ± 71 s P = 0.00). Conclusion: Preprocedural ultrasound imaging increased the incidence of first pass success in thoracic epidural catheter insertion and reduced the catheter insertion time compared to manual palpation method.
Vitamin D Levels in Asymptomatic Adults-A Population Survey in Karachi, Pakistan

Background It is well established that low levels of 25(OH) Vitamin D (<30 ng/dL) are a common finding world over, affecting over a billion of the global population. Our primary objective was to determine the prevalence of vitamin D deficiency and insufficiency in the asymptomatic adult population of Karachi, Pakistan and the demographic, nutritional and co-morbidity characteristics associated with serum vitamin D levels. Methods A cross-sectional population survey was conducted at two spaced out densely populated areas of the city. Serum levels of 25OHVitamin D were measured and GFR as renal function was assessed by using 4 variable MDRD formula. Results Our sample of 300 had a median age of 48(interquartile range 38–55) years. The median level of serum vitamin D was 18.8 (IQ range 12.65–24.62) ng/dL. A total of 253 (84.3%) respondents had low levels (<30 ng/dL) of 25OH vitamin D. Serum PTH and vitamin D were negatively correlated (r = −0.176, p = 0.001). The median PTH in the vitamin D sufficiency group was 38.4(IQ range28.0–48.8)pg/mL compared with 44.4(IQ range34.3–56.8) pg/mL in the deficiency group (p = 0.011). The median serum calcium level in the sample was 9.46(IQ range 9.18–9.68) ng/dL. Low serum levels of vitamin D were not associated with hypertension (p = 0.771) or with an elevated spot blood pressure (p = 0.164). In our sample 75(26%) respondents had an eGFR corresponding to stage 2 and stage 3 CKD. There was no significant correlation between levels of vitamin D and eGFR (r = −0.127, p-value = 0.277). Respondents using daily vitamin D supplements had higher 25 OH vitamin D levels (p-value = 0.021). Conclusion We observed a high proportion of the asymptomatic adult population having low levels of vitamin D and subclinical deterioration of eGFR. The specific cause(s) for this observed high prevalence of low 25OH vitamin D levels are not clear and need to be investigated further upon.
Chitosan Dermal Substitute and Chitosan Skin Substitute Contribute to Accelerated Full-Thickness Wound Healing in Irradiated Rats

Wounds with full-thickness skin loss are commonly managed by skin grafting. In the absence of a graft, reepithelialization is imperfect and leads to increased scar formation. Biomaterials can alter wound healing so that it produces more regenerative tissue and fewer scars. This current study use the new chitosan based biomaterial in full-thickness wound with impaired healing on rat model. Wounds were evaluated after being treated with a chitosan dermal substitute, a chitosan skin substitute, or duoderm CGF. Wounds treated with the chitosan skin substitute showed the most re-epithelialization (33.2 ± 2.8%), longest epithelial tongue (1.62 ± 0.13 mm), and shortest migratory tongue distance (7.11 ± 0.25 mm). The scar size of wounds treated with the chitosan dermal substitute (0.13 ± 0.02 cm) and chitosan skin substitute (0.16 ± 0.05 cm) were significantly decreased (P < 0.05) compared with duoderm (0.45 ± 0.11 cm). Human leukocyte antigen (HLA) expression on days 7, 14, and 21 revealed the presence of human hair follicle stem cells and fibroblasts that were incorporated into and surviving in the irradiated wound. We have proven that a chitosan dermal substitute and chitosan skin substitute are suitable for wound healing in full-thickness wounds that are impaired due to radiation.
The origin of Titan's atmosphere: some recent advances

It is possible to make a consistent story for the origin of Titan's atmosphere starting with the birth of Titan in the Saturn subnebula. If we use comet nuclei as a model, Titan's nitrogen and methane could have easily been delivered by the ice that makes up approximately 50 per cent of its mass. If Titan's atmospheric hydrogen is derived from that ice, it is possible that Titan and comet nuclei are in fact made of the same protosolar ice. The noble gas abundances are consistent with relative abundances found in the atmospheres of Mars and Earth, the Sun, and the meteorites.
ATPase Activity of Mycobacterium tuberculosis SecA1 and SecA2 Proteins and Its Importance for SecA2 Function in Macrophages

ABSTRACT The Sec-dependent translocation pathway that involves the essential SecA protein and the membrane-bound SecYEG translocon is used to export many proteins across the cytoplasmic membrane. Recently, several pathogenic bacteria, including Mycobacterium tuberculosis, were shown to possess two SecA homologs, SecA1 and SecA2. SecA1 is essential for general protein export. SecA2 is specific for a subset of exported proteins and is important for M. tuberculosis virulence. The enzymatic activities of two SecA proteins from the same microorganism have not been defined for any bacteria. Here, M. tuberculosis SecA1 and SecA2 are shown to bind ATP with high affinity, though the affinity of SecA1 for ATP is weaker than that of SecA2 or Escherichia coli SecA. Amino acid substitution of arginine or alanine for the conserved lysine in the Walker A motif of SecA2 eliminated ATP binding. We used the SecA2(K115R) variant to show that ATP binding was necessary for the SecA2 function of promoting intracellular growth of M. tuberculosis in macrophages. These results are the first to show the importance of ATPase activity in the function of accessory SecA2 proteins.
Recalling Past Temptations: An Information-Processing Perspective on the Dynamics of Self-Control

This research investigates how consumers respond to food-related temptations as a function of recalling their own behavior when faced with a similar temptation in the recent past. Bringing together different streams of relevant research, we propose and find that chronically nonimpulsive individuals display behavioral consistency over time-resisting (succumbing) when they recall having resisted (succumbed) earlier. In contrast, impulsive individuals show a switching pattern, resisting current temptations if they recall having succumbed, and vice versa. These propositions are supported by convergent results across four experiments involving real eating behaviors, response latencies, and hypothetical choices. Implications for consumer welfare are discussed and possible interventions are suggested. (c) 2008 by JOURNAL OF CONSUMER RESEARCH, Inc.
Maximizing the number of independent subsets over trees with bounded degree

The number of independent vertex subsets is a graph parameter that is, apart from its purely mathematical importance, of interest in mathematical chemistry. In particular, the problem of maximizing or minimizing the number of independent vertex subsets within a given class of graphs has already been investigated by many authors. In view of the applications of this graph parameter, trees of restricted degree are of particular interest. In the current article, we give a characterization of the trees with given maximum degree which maximize the number of independent subsets, and show that these trees also minimize the number of independent edge subsets. The structure of these trees is quite interesting and unexpected: it can be described by means of a novel digital system—in the case of maximum degree 3, we obtain a binary system using the digits 1 and 4. The proof mainly depends on an exchange lemma for branches of a tree. © 2008 Wiley Periodicals, Inc. J Graph Theory 58: 49–68, 2008
Comunicación, cohesión y satisfacción familiar en adolescentes de la enseñanza secundaria y preuniversitaria. Cienfuegos 2014

Foundation: The family is the instance of intermediation between the individual and society, it constitutes the space par excellence for adolescent identity development, being the first group of socialization and provide the conditions for healthy personality development. Objective: to determine the type of communication, the level of cohesion and the degree of family satisfaction in adolescents who attend senior high and high education centers. Methods: A descriptive study was carried out from January to March 2014 in 62 adolescents from the municipality of Cienfuegos, selected at random stratified by sex. The following techniques were applied: structured interview, questionnaires to measure adolescent-mother communication and adolescent-parent communication, subscale of family cohesion and instrument to measure family satisfaction. Results: 13 and 16-year-old adolescents predominated in medium-sized, nuclear, bigenerational families that are in the extension stage. Positive communication, high cohesion and family satisfaction prevailed in the average adolescents. In late adolescents communication is limited, they have intermediate level of cohesion and are dissatisfied with their families. Conclusions: the average adolescents showed good communication with parents, family unit and satisfaction. In the late adolescents qualitative changes were verified regarding the communication with parents, they did not feel so close to their family and showed little satisfaction.
Neurological soft signs, temperament and schizotypy in patients with schizophrenia and unaffected relatives: an FMRI study

Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. The genetic basis may be present in individuals without disease, as in the case of relatives of patients, being detectable through biological markers. This study explores the abnormalities in the functional connectivity of the default mode network related to the association between neurological soft signs and personality in schizophrenia. A cross-sectional study comparing 3 groups: patients with schizophrenia, unaffected relatives and healthy controls. In order to explore the association of these potential biomarkers of schizophrenia the study was composed of two parts: • Neurological soft signs and personality traits: the Temperament and Character Inventory, the Schizotypal Personality Questionnaire and an evaluation of Neurological Soft Signs were performed. • Functional connectivity in the default mode network and neurological soft signs: a fMRI resting state was performed. The major finding in this study was that patients with schizophrenia and nonpsychotic relatives display a unique profile of temperament and character and higher schizotypal traits that correlate with higher presence of NSS. The neuroimaging results showed connectivity changes in the DMN with a possible association with the presence of neurological soft signs. These findings support the theory of cognitive dysmetria as a possible dysfunction in cortical-thalamic-cerebellar connectivity of the schizophrenia. This model also could explain the diversity of symptoms in schizophrenia and their associations (like this study that includes personality and sensory and motor functions).
Lateralization of the arcuate fasciculus from childhood to adulthood and its relation to cognitive abilities in children

The arcuate fasciculus is a major white matter tract involved in language processing that has also been repeatedly implicated in intelligence and reasoning tasks. Language in the human brain is lateralized in terms of both function and structure, and while the arcuate fasciculus reflects this asymmetry, its pattern of lateralization is poorly understood in children and adolescents. We used diffusion tensor imaging (DTI) and tractography to examine arcuate fasciculus lateralization in a large (n = 183) group of healthy right‐handed volunteers aged 5–30 years; a subset of 68 children aged 5–13 years also underwent cognitive assessments. Fractional anisotropy and number of streamlines of the arcuate fasciculus were both significantly higher in the left hemisphere than the right hemisphere in most subjects, although some subjects (10%) were right lateralized. Age and gender effects on lateralization were not significant. Children receiving cognitive assessments were divided into three groups: a “left‐only” group in whom only the left side of the arcuate fasciculus could be tracked, a left‐lateralized group, and a right‐lateralized group. Scores on the Peabody Picture Vocabulary Test (PPVT) and NEPSY Phonological Processing task differed significantly among groups, with left‐only subjects outperforming the right‐lateralized group on the PPVT, and the left‐lateralized children scoring significantly better than the right‐lateralized group on phonological processing. In summary, DTI tractography demonstrates leftward arcuate fasciculus lateralization in children, adolescents, and young adults, and reveals a relationship between structural white matter lateralization and specific cognitive abilities in children. Hum Brain Mapp, 2009. © 2009 Wiley‐Liss, Inc.
Performance of MPR-based broadcast methods in mobile ad hoc networks for rural terrains

With the aim of achieving robust broadcasting, the paper explores how the terrain affects different MPR-based broadcast methods. As a reference we consider the MPR selection method in OLSR and investigate methods for increasing robustness by the using of physical layer information and additional MPRs. It is also important to consider the overhead of these methods. To assess how terrain properties influence performance we consider mobile scenarios in different rural terrains. A channel model that mimics real radio transmissions and includes terrain effects is employed. The plane earth model is also tested. The terrain has a large influence on overall performance, and the results obtained with the plane earth model can produce misleading results. However, when determining how to select MPR nodes, network connectivity is the main criteria to use.
Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor

Hen egg lysozyme 52-61-specific CD4+ T cells responded by interleukin 2 (IL-2) secretion to any peptide containing this epitope regardless of length of NH2- and COOH-terminal composition. However, CD4- variants could only respond to peptides containing the two COOH-terminal tryptophans at positions 62 and 63. Substitutions at these positions defined patterns of reactivity that were specific for individual T cells inferring a T cell receptor (TCR)-based phenomenon. Thus, the fine specificity of major histocompatibility complex (MHC)-peptide recognition by the TCR was dramatically affected by CD4 and the COOH- terminal peptide composition. Peptides that failed to induce IL-2 secretion in the CD4- variants nevertheless induced strong tyrosine phosphorylation of CD3 zeta. Thus, whereas the TCR still recognized and bound to the MHC class II-peptide complex resulting in protein phosphorylation, this interaction failed to induce effective signal transduction manifested by IL-2 secretion. This provides a clear example of differential signaling mediated by peptides known to be naturally processed. In addition, the external domains of CD4, rather than its cytoplasmic tail, were critical in aiding TCR recognition of all peptides derived from a single epitope. These data suggest that the nested flanking residues, which are present on MHC class II but not class I bound peptides, are functionally relevant.
Subjective Somatosensory Experiences Disclosed by Focused Attention: Cortical-Hippocampal-Insular and Amygdala Contributions

In order to explore the neurobiological foundations of qualitative subjective experiences, the present study was designed to correlate objective third-person brain fMRI measures with subjective first-person identification and scaling of local, subtle, and specific somatosensory sensations, obtained directly after the imaging procedure. Thus, thirty-four volunteers were instructed to focus and sustain their attention to either provoked or spontaneous sensations of each thumb during the fMRI procedure. By means of a Likert scale applied immediately afterwards, the participants recalled and evaluated the intensity of their attention and identified specific somatosensory sensations (e.g. pulsation, vibration, heat). Using the subject's subjective scores as covariates to model both attention intensity and general somatosensory experiences regressors, the whole-brain random effect analyses revealed activations in the frontopolar prefrontal cortex (BA10), primary somatosensory cortex (BA1), premotor cortex (BA 6), precuneus (BA 7), temporopolar cortex (BA 38), inferior parietal lobe (BA 39), hippocampus, insula and amygdala. Furthermore, BA10 showed differential activity, with ventral BA10 correlating exclusively with attention (r(32) = 0.54, p = 0.0013) and dorsal BA10 correlating exclusively with somatosensory sensation (r(32) = 0.46, p = 0.007). All other reported brain areas showed significant positive correlations solely with subjective somatosensory experiences reports. These results provide evidence that the frontopolar prefrontal cortex has dissociable functions depending on specific cognitive demands; i.e. the dorsal portion of the frontopolar prefrontal cortex in conjunction with primary somatosensory cortex, temporopolar cortex, inferior parietal lobe, hippocampus, insula and amygdala are involved in the processing of spontaneous general subjective somatosensory experiences disclosed by focused and sustained attention.
Buri

Motivated by the challenges of scaling up memory capacity and fully exploiting the benefits of memory compression, we propose Buri, a hardware-based memory compression scheme, which simultaneously achieves cost efficiency, high performance, and ease of adoption. Buri combines (1) a self-contained, ready-to-adopt hardware compression module, which manages metadata compression and memory allocation/relocation operations; (2) a set of hardware optimization mechanisms, which reduce the area and performance overheads in accommodating the address indirection required by memory compression; and (3) lightweight BIOS/OS extensions used to handle exceptions. Our evaluation with large memory workload traces shows that Buri can increase capacity by 70%, in addition to the compression ratio already provided by database software.
Flourishing: Why We Need Religion in a Globalized World

A celebrated theologian explores how the greatest dangers to humanity, as well as the greatest promises for human flourishing, are at the intersection of religion and globalization More than almost anything else, globalization and the great world religions are shaping our lives, affecting everything from the public policies of political leaders and the economic decisions of industry bosses and employees, to university curricula, all the way to the inner longings of our hearts. Integral to both globalization and religions are compelling, overlapping, and sometimes competing visions of what it means to live well. In this perceptive, deeply personal, and beautifully written book, a leading theologian sheds light on how religions and globalization have historically interacted and argues for what their relationship ought to be. Recounting how these twinned forces have intersected in his own life, he shows how world religions, despite their malfunctions, remain one of our most potent sources of moral motivation and contain within them profoundly evocative accounts of human flourishing. Globalization should be judged by how well it serves us for living out our authentic humanity as envisioned within these traditions. Through renewal and reform, religions might, in turn, shape globalization so that can be about more than bread alone.