Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficient Hashing for Dynamic Per-Flow Network-Interface Selection

Although most smartphones today have both cellular data and WiFi capacity, network-selection techniques typically only allow for a single data interface to be used at a time. This leads to several problems including the interruption of existing connections when switching interfaces, complete loss of connectivity when the selected network is not functioning correctly, and significantly less bandwidth to the device than is possible if the available wireless capacity is aggregated. While interface bonding is not new, aggregating two such diverse networks is particularly challenging given that different wireless technologies, and even different networks of the same type, offer inconsistent link parameters, presenting dynamically fluctuating bandwidth, latency, and packet loss. In this paper we present a simple, but extremely efficient, hashing technique for multi-interface packet scheduling. We have implemented our system with aggregation proxies running in well-connected data centers and client code running on a Galaxy Nexus running Android 4.1. Our experimental results show that our prototype never loses connectivity even when networks fail as long as at least one network is functioning, does not break connections as interface selection is adjusted, and can increase bandwidth to the smartphone to the available aggregated network capacities. Transmission time is reduced by up to 60% vs. using a single network interface.
The Luminosity-Metallicity relation of distant luminous infrared galaxies

One hundred and five 15 µm-selected objects in three ISO (Infrared Space Observatory) deep survey fields (CFRS 3 h , UDSR and UDSF) are studied on the basis of their high-quality optical spectra with resolution R > 1000 from VLT/FORS2. ∼92 objects (88%) have secure redshifts, ranging from 0 to 1.16 with a median value of zmed = 0.587. Considerable care is taken in estimating the extinction properties of individual galaxy, which can seriously affect diagnostic diagrams and estimates of star formation rates (SFRs) and of metal abundances. Two independent estimates of the extinction have been made, e.g. Balmer line ratio and energy balance between infrared (IR) and Hβ luminosities. For most of the sources, we find a good agreement between the two extinction coefficients (within ±0.64 rms in AV , the extinction in V band), with median values of AV (IR) = 2.36 and AV (Balmer) = 1.82 for z > 0.4 luminous IR galaxies (LIRGs). At z > 0.4, our sample show many properties (IR luminosity, continuum color, ionization and extinction) strikingly in common with those of local (IRAS) LIRGs studied by Veilleux et al. (1995). Thus, our sample can provide a good representation of LIRGs in the distant Universe. We confirm that most (>77%) ISO 15 µm-selected galaxies are dominated by star formation. Oxygen abundances in interstellar medium in the galaxies are estimated from the extinction-corrected "strong" emission line ratios (e.g. (O )/Hβ ,( O)/Hβ and (O )/(O )). The derived 12+log(O/H) values range from 8.36 to 8.93 for the z > 0.4 galaxies with a median value of 8.67. Distant LIRGs present a metal content less than half of that of the local bright disks (i.e. L ∗ ). Their properties can be reproduced with infall models although one has to limit the infall time to avoid overproduction of metals at late times. The models predict that total masses (gas + stars) of the distant LIRGs are from 10 11 Mto ≤10 12 M� . A significant fraction of distant large disks are indeed LIRGs. Such massive disks could have formed ∼50% of their metals and stellar masses since z ∼ 1.
Sulforaphane enhances progerin clearance in Hutchinson–Gilford progeria fibroblasts

Hutchinson–Gilford progeria syndrome (HGPS, OMIM 176670) is a rare multisystem childhood premature aging disorder linked to mutations in the LMNA gene. The most common HGPS mutation is found at position G608G within exon 11 of the LMNA gene. This mutation results in the deletion of 50 amino acids at the carboxyl‐terminal tail of prelamin A, and the truncated protein is called progerin. Progerin only undergoes a subset of the normal post‐translational modifications and remains permanently farnesylated. Several attempts to rescue the normal cellular phenotype with farnesyltransferase inhibitors (FTIs) and other compounds have resulted in partial cellular recovery. Using proteomics, we report here that progerin induces changes in the composition of the HGPS nuclear proteome, including alterations to several components of the protein degradation pathways. Consequently, proteasome activity and autophagy are impaired in HGPS cells. To restore protein clearance in HGPS cells, we treated HGPS cultures with sulforaphane (SFN), an antioxidant derived from cruciferous vegetables. We determined that SFN stimulates proteasome activity and autophagy in normal and HGPS fibroblast cultures. Specifically, SFN enhances progerin clearance by autophagy and reverses the phenotypic changes that are the hallmarks of HGPS. Therefore, SFN is a promising therapeutic avenue for children with HGPS.
Reversible inactivation of monkey superior colliculus. II. Maps of saccadic deficits.

Neurons in the superior colliculus (SC) are organized as maps of visual and motor space. The companion paper showed that muscimol injections into intermediate layers of the SC alter the trajectory of the movement and confirmed previously reported effects on latency, amplitude, and speed of saccades. In this paper we analyze the pattern of these deficits across the visual field by systematically comparing the magnitude of each deficit throughout a grid of targets covering a large fraction of the visual field. We also translate these deficits onto the SC map of the visual/movement fields to obtain a qualitative estimate of the extent of the deficit in the SC. We found a consistent pattern of substantially increased saccadic latency to targets in the contralateral visual hemifield, accompanied by slight and inconsistent increases and decreases for saccades to the ipsilateral hemifield. The initial and peak speed of saccades was reduced after the injection. The postinjection amplitude of the saccades were either hypometric or normometric, but rarely hypermetric. Although errors in the initial direction of the postinjection saccades were small, they consistently formed a simple pattern: an initial direction with minimal errors (a null direction) separating regions with clockwise and counterclockwise rotations of the initial direction. However, the null direction did not go through the center of the inactivated zone, as would be expected if the SC alone were determining saccade direction, e.g., with a population code. One hypothesis that can explain the misalignment of the null direction with the lesion site is that another system, acting in parallel with the SC, contributes to the determination of saccadic trajectory.
The Circulation of Climate Change Denial Online: Rhetorical and Networking Strategies on Facebook

ABSTRACT This study uses a topical, rhetorical approach to analyze how climate change denial circulates online through the 25 most popular posts on the Watts Up With That and the Global Warming Policy Forum Facebook pages. These groups adopt the appearance of credibility through reposting and hyperlinking, thus establishing a supportive, networked space among other skeptical sites, while distancing readers from original sources of scientific information. Visitors use a variety of rhetorical strategies to echo posts’ main themes and to discredit alternative viewpoints. Differences between the topoi and rhetorical strategies of WUWT and the GWPF show that the climate change denial community is multifaceted and makes use of social media affordances to craft the appearance of legitimacy. This project contributes to our knowledge of how scientific information is co-opted, manipulated, and circulated in online spaces and how online features shape environmental discourse practices.
A serum piRNA signature as promising non-invasive diagnostic and prognostic biomarkers for colorectal cancer

Purpose: Piwi-interacting RNAs (piRNAs) are a novel class of small non-coding RNAs, which are not easily degraded but detectable in human body fluids. Recent studies have shown that aberrant piRNA expression is a signature feature across multiple tumor types. However, the expressions of piRNAs in serum of tumor patients and their potential clinical values remain largely unclear. Patients and methods: High-throughput sequencing was performed to investigate the serum piRNA profiles, followed by evaluations in serum samples of 220 colorectal cancer (CRC) patients and 220 healthy controls using reverse transcription quantitative real-time PCR (RT-qPCR). Biomarker panels including piRNA-based Panel I and carcinoembryonic antigen (CEA)-based Panel II, were developed by logistic regression model, and their diagnostic potentials were compared. Fagan’s nomogram was plotted to promote clinical application. Results: We identified five differentially expressed serum piRNAs (piR-001311, piR-004153, piR-017723, piR-017724 and piR-020365), which, when combined in the piRNA-based Panel I, outperformed the CEA-based Panel II (P<0.001) and could detect CRC with an area under the receiver operating characteristic curve of 0.867. In addition, Kaplan–Meier analysis showed that patients with low serum piR-017724 level had worse overall survival (OS) and progression-free survival (PFS). In multivariate Cox regression analysis, serum piR-017724 was an independent prognostic factor for OS and PFS (P<0.05). Conclusion: Our findings suggest serum piRNA expression signatures have potential for use as biomarkers for CRC detection and to predict prognosis at the time of diagnosis.
‘Now it's indie’: The creative turn of the cultural policy in the Korean indie music scene

As creative industry policy discourse has travelled quickly across the South Korean cultural industry, including the Korean Wave and beyond, the indie music artists in South Korea have found opportunities to perform and promote their music overseas. The recent cultural policy along with the direct support programs are unexpected, because of the conservative nature of the government and the nature of the South Korean indie music as independent from political and economic powers. With the example of the overseas advance of South Korean indie artists, with government support, this article presents an examination of the complex relationship between the government's creative cultural policy and the resulting effects of the policies on the South Korean indie music scene. It is argued that it is yet to be determined whether the cultural policy is having a negative or positive effect on the cultural industry. This article suggests that the cultural policy, whatever the goals of the policy-makers, is interacting with other elements—such as the political economy of the technologies of distribution and consumption, subculture, and the methods through which the cultural policy discourse is articulated among the policy community—beyond the objectives of the policy itself.
Revisiting the Relationship between Urban Form and Excess Commuting in US Metropolitan Areas

This article revisits the relationship between urban form and excess commuting by analyzing 206 metropolitan statistical areas in the United States. Using the most recent Census Transportation Planning Products, we revalidated the importance of using multidimensional indices when examining excess commuting across metropolitan areas. We found that higher levels of polycentricity aggravate cross-commuting, while higher central city dominance improves excess commuting. In addition, our results indicate the significant impact of sprawl or jobs–housing dispersal on excess commuting. These findings shed light on the multidimensional relationship between urban form and excess commuting.
Spider webs designed for rare but life-saving catches

The impact of rare but positive events on the design of organisms has been largely ignored, probably due to the paucity of recordings of such events and to the difficulty of estimating their impact on lifetime reproductive success. In this respect, we investigated the size of spider webs in relation to rare but large prey catches. First, we collected field data on a short time-scale using the common orb-weaving spider Zygiella x-notata to determine the distribution of the size of prey caught and to quantify the relationship between web size and daily capture success. Second, we explored, with an energetic model, the consequences of an increase in web size on spider fitness. Our results showed that (i) the great majority of prey caught are quite small (body length less than 2 mm) while large prey (length greater than 10 mm) are rare, (ii) spiders cannot survive or produce eggs without catching these large but rare prey and (iii) increasing web size increases the daily number of prey caught and thus long-term survival and fecundity. Spider webs seem, therefore, designed for making the best of the rare but crucial event of catching large prey.
The Effect of Self Efficacy and Information Quality on Behavioral Intention with Perceived Usefulness as Intervening Variable

The rapid development of technology requires universities to develop an integrated academic information system to support the education process. With the application of the information system, universities can provide better information services to students. The aim of this study is to examine the influence of self-efficacy and information quality on behavioral intention toward academic information system with perceived usefulness as an intervening variable. This study used survey questionnaire in collecting data from one higher institution - STIE Malangkuçeçwara(Malangkuçeçwara School of Economic). The population in this study is all students in the sixth semester. A questionnaire was administered to all 377 students, 311 were returned yielding a response rate 82.5%. This study has three significant findings. First, the direct effect of self-efficacy on behavioral intention to use academic information system (AIS) is significant. Second, the direct effect of information quality on behavioral intention to use AIS is significant. Third, The indirect effect of self-efficacy and information quality on behavioral intention to use AIS through perceived usefulness is not significant
The Effect of Magnitude and Direction of Heat Flow on the Thermal Conductivity for Insulation Materials (Glass Wool) by Using Probe Method

The thermal energy of building is determined by the thermal properties of the materials and how to install these materials in the elements of buildings according to the direction of heat transfer. The effectiveness of thermal insulation (glass wool) is dependent on its thermal conductivity which is varies in different directions of fibers of glass wool. Glass wool is formed of fibers and binders tangled together during the industrial process to provide some elasticity. The experimental values of thermal conductivity of the insulation materials are changed according to magnitude of the heat power and direction of fiber arrangement. The thermal conductivity for insulation materials has been measured by using probe method, Huekseflux ® TP02 used to measure the thermal conductivity by emit the flow perpendicular and parallel to the fibers of glass wool. Two samples of yellow glass wool (density 68 kg/m3) with dimensions (10 ×10 ×30) cm have been used. Hot Disk bulk isotropic module has been used to evaluate thermal conductivity. TPS source (Hot Disk probe reference: 4922) characterized by a diameter of 14.61 mm has been selected. COMSOL® multiphysics axisymmetric 2D model has been used to follow the axial and the radial directions of the heat transfer.
An Improved Proxy Blind Signature Scheme With Forward Security

This paper presents a proxy blind signature scheme with forward security mechanism. The proposed digital signature scheme combines the two special-purpose signature schemes, blind signature and proxy signature. In this signature scheme, the original signer gives authority to another entity which is known as a proxy signer, but without having any idea about the content of the document. This paper, proposes an enhanced proxy blind signature, in which the forward security is incorporated and the security of the signature scheme relies on the discrete logarithm problem (DLP). Forward security mechanism will provide protection to the system from the key leakage or key exposure, because in this mechanism, the private key of proxy signer is updated periodically. In case if the signature key at some stage is compromised, the adversary cannot be able to forge signatures as if they had been generated before the exposure or leakage of key.
Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli

In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance of fragmented chromosomes and a decrease in terminus concentration, leading to a dramatic increase in ori/ter ratio and cessation of cell growth. Aerobic viability was restored by reducing the level of reactive oxygen species (ROS) or by deleting mutM (Fpg glycosylase). The double-strand breaks observed in hyperinitiating cells therefore results from replication forks encountering single-stranded DNA lesions generated while removing oxidized bases, primarily 8-oxoG, from the DNA. We conclude that there is a delicate balance between chromosome replication and ROS inflicted DNA damage so the number of replication forks can only increase when ROS formation is reduced or when the pertinent repair is compromised.
TurkerGaze: Crowdsourcing Saliency with Webcam based Eye Tracking

Traditional eye tracking requires specialized hardware, which means collecting gaze data from many observers is expensive, tedious and slow. Therefore, existing saliency prediction datasets are order-of-magnitudes smaller than typical datasets for other vision recognition tasks. The small size of these datasets limits the potential for training data intensive algorithms, and causes overfitting in benchmark evaluation. To address this deficiency, this paper introduces a webcam-based gaze tracking system that supports large-scale, crowdsourced eye tracking deployed on Amazon Mechanical Turk (AMTurk). By a combination of careful algorithm and gaming protocol design, our system obtains eye tracking data for saliency prediction comparable to data gathered in a traditional lab setting, with relatively lower cost and less effort on the part of the researchers. Using this tool, we build a saliency dataset for a large number of natural images. We will open-source our tool and provide a web server where researchers can upload their images to get eye tracking results from AMTurk.
Swinging Door Invariants: Optical Information from Rotating Panels

Abstract Ecological perceptual research focuses on stimulus array invariants as information that might guide organismic (particularly human) actions. Constructed by human agency, built environments entail structural regularities (e.g., planarity, verticality, horizontality, orthogonality) that constrain stimulus array information; here the emphasis is optical information (invariants). Built environments involve barriers that restrict behavior; doors allow passage through such barriers. Doors (more generally, swinging panels) yield surprisingly many instances of optical information. Specifically, invariants exist for (a) panel collision and bypass, (b) the panel’s axis of rotation, (c) the horizon line, and (d) the panel’s frontal-parallel orientation. Affordances are associated with each of those. Invariants described exemplify meta-invariant patterns (i.e., similarities in invariant stimulus array structure that occur across disparate environmental objects and events); meta-invariants may serve as research heuristics for the discovery of invariants in delimited contexts. Empirical considerations for optical invariants identified are described. Derivations described may be helpful for teaching the concept of invariants from stimulus array transformations, as well.
Distributed Irregular Finite Elements

DIME is a programming environment for manipulation of irregular triangular meshes with a distributed memory machine. We have added a software layer DIMEFEM which manipulates Finite Element representations of functions and allows the stating and solving of variational statements. An application of DIMEFEM is an incompressible Navier-Stokes solver with a three-stage implicit time step, using quasi-optimally preconditioned conjugate gradient for the Stokes solver and Newtons’ method in the space of quadratic Lagrangian elements for the nonlinear solver. The codes run on NCUBE hypercubes and transputer machines. *Concurrent Supercomputing Facility California Institute of Technology Pasadena, CA 91125 USA C3P 715 February 1989 **Mathematics Department University of Houston Houston, TX 77004 USA
Effects of training on timbre recognition and appraisal by postlingually deafened cochlear implant recipients.

The purpose of this study was to compare the effect of structured training on recognition and appraisal of the timbre (tone quality) of musical instruments by postlingually deafened cochlear implant recipients. Twenty-four implant users (Nucleus CI24M) were randomly assigned to a control or a training group. The control group experienced only incidental exposure to music in their usual daily routine. The training group participated in 12 weeks of training delivered via a laptop computer in which they were introduced to excerpts of musical instruments representing three frequency ranges and four instrumental families. Those implant recipients assigned to the training group showed significant improvement in timbre recognition (p < .0001) and timbre appraisal (p < .02) compared to the control group. Correlations between timbre measures and speech perception measures are discussed.
How to Assess the Existence of Competing Strategies in Cognitive Tasks: A Primer on the Fixed-Point Property

When multiple strategies can be used to solve a type of problem, the observed response time distributions are often mixtures of multiple underlying base distributions each representing one of these strategies. For the case of two possible strategies, the observed response time distributions obey the fixed-point property. That is, there exists one reaction time that has the same probability of being observed irrespective of the actual mixture proportion of each strategy. In this paper we discuss how to compute this fixed-point, and how to statistically assess the probability that indeed the observed response times are generated by two competing strategies. Accompanying this paper is a free R package that can be used to compute and test the presence or absence of the fixed-point property in response time data, allowing for easy to use tests of strategic behavior.