Miracle-dz/UniFAR-FTUs huggingface dataset:
Tempering Process and Precipitation Behavior of 8%Cr–2%WTa Steel

In order to clarify the stability of precipitates in 8%Cr-2%W-0.09%Ta steel at high temperatures, tempering and precipitation behavior of the steel has been examined precisely. Tempering was performed mainly at 740°C for 0.5-1 000 h. Hardness peak was found in a tempering curve at 650-740°C for 3.75-8 h. Discontinuous changes in X-ray diffraction intensity of the matrix, apparent lattice strain and apparent crystalline particle size, which were estimated from integral breadth, the amount of extracted residue, and the Cr and Ta content in the residue were observed at 740°C for 2-12 h tempering. These discontinuous changes correspond to the rotation of preferred orientation or the generation of subgrains accompanying the dissolution and the subsequent re-precipitation of M 23 C 6 and TaC. The re-precipitation of fine M 23 C 6 particles is responsible for the hardness peak. Three kinds of TaC with different chemical composition and different size are found. The amount and the size of the coarse and medium TaC particles are affected by the discontinuous changes in microstructure. Fine particles of TaC grow very slowly, which is caused by the continuous dissolution of TaC due to the annihilation of precipitation site, dislocations, and re-precipitation on dislocations. Particle sizes of TaC and M 23 C 6 estimated using X-ray diffraction peak coincide with those observed in transmission electron microscopy.
Homology search for genes

MOTIVATION Life science researchers often require an exhaustive list of protein coding genes similar to a given query gene. To find such genes, homology search tools, such as BLAST or PatternHunter, return a set of high-scoring pairs (HSPs). These HSPs then need to be correlated with existing sequence annotations, or assembled manually into putative gene structures. This process is error-prone and labor-intensive, especially in genomes without reliable gene annotation. RESULTS We have developed a homology search solution that automates this process, and instead of HSPs returns complete gene structures. We achieve better sensitivity and specificity by adapting a hidden Markov model for gene finding to reflect features of the query gene. Compared to traditional homology search, our novel approach identifies splice sites much more reliably and can even locate exons that were lost in the query gene. On a testing set of 400 mouse query genes, we report 79% exon sensitivity and 80% exon specificity in the human genome based on orthologous genes annotated in NCBI HomoloGene. In the same set, we also found 50 (12%) gene structures with better protein alignment scores than the ones identified in HomoloGene. AVAILABILITY The Java implementation is available for download from http://www.bioinformatics. uwaterloo.ca/software.
What can visual speech synthesis tell visual speech recognition?

We consider the problem of speech recognition given visual and auditory information, and discuss some of the ways that speech synthesis can provide assistance. Three possible contributions of synthetic visual speech are discussed. First, the use of synthetic speech to study human speech perception, second, the use of speech synthesis techniques to instantiate models of human speech production, and third, the use of these production models to help guide automatic speech recognition. Finally, we consider the reverse relationship. How can the techniques of automatic speech recognition assist in better visual speech synthesis? <<ETX>>
Texture Anisotropy of the Brain's White Matter as Revealed by Anatomical MRI

The purpose of this work was to study specific texture properties of the brain's white matter (WM) based on conventional high-resolution T 1-weighted magnetic resonance imaging (MRI) datasets. Quantitative parameters anisotropy and laminarity were derived from 3-D texture analysis. Differences in WM texture associated with gender were evaluated on an age-matched sample of 210 young healthy subjects (mean age 24.8, SD 3.97 years, 103males and 107 females). Changes of WM texture with age were studied using 112 MRI-T1 datasets of healthy subjects aged 16 to 70years (57 males and 55 females). Both texture measures indicated a "more regular" WM structure in females (p<10-6). An age-related deterioration of WM structure manifests itself as a remarkable decline of both parameters (p<10-6) that is more prominent in females (p<10-6 ) than in males (p=0.02). Texture analysis of anatomical MRI-T1 brain datasets provides quantitative information about macroscopic WM characteristics and helps discriminating between normal and pathological aging
Investigation of solidification microstructure of single crystal CMSX-4 superalloy – experimental measurements and modelling predictions

The solidification microstructure development of single crystal CMSX-4 superalloy produced by the Bridgman method was investigated through experimental measurements and numerical modelling. The numerical investigation was performed using the commercial software ProCAST/CAFE and included the following variables: nucleation potential, heat transfer coefficients and emissivity. The predicted solidification microstructure, nucleation and growth, single grain selection and texture to the growth direction < 001> were validated by SEM microstructural and X-ray diffraction investigations. Modelling predictions of the temperature gradient and of the solidification velocity for different heat extraction conditions were used to calculate the primary and secondary arm spacing evolution with the distance from the cooling plate. The results were calibrated with experimental measurements, and fitted equations were established as a function of temperature gradient and solidification rates. It was found that appropriate selection of the numerical modelling input parameters allows prediction of microstructural features that match reasonably well the experimentally measured ones.
Rate of Lineage Origin Explains the Diversity Anomaly in the World’s Mangrove Vegetation

The contribution of nonecological factors to global patterns in diversity is evident when species richness differs between regions with similar habitats and geographic area. Mangrove environments in the Eastern Hemisphere harbor six times as many species of trees and shrubs as similar environments in the New World. Genetic divergence of mangrove lineages from terrestrial relatives, in combination with fossil evidence, suggests that mangrove diversity is limited by evolutionary transition into the stressful marine environment, the number of mangrove lineages has increased steadily over the Tertiary with little global extinction, and the diversity anomaly in mangrove vegetation reflects regional differences in the rate of origin of new mangrove lineages.
Low-complex frame synchronization in OFDM systems

Orthogonal frequency-division multiplexing (OFDM) systems have gained an increased interest due to their use in wireless applications such as mobile communication systems. A novel data-based frame synchronization method for OFDM-systems is presented. OFDM frames are shown to contain sufficient information to synchronize a system without the use of pilots. The cyclic extension, preceding OFDM frames, is of decisive importance for this method. Based on only the sign bits of the in-phase and the quadrature components of the received OFDM signal, the maximum likelihood solution is derived. This solution basically consists of a correlator, a moving sum and a peak detector. The stability of the generated frame-clock is improved significantly by averaging over a few number of frames. Simulations show that this low-complex, averaging method can be used to synchronize an OFDM system on twisted pair copper wires and in slowly fading radio channels.
A STUDY OF THE BEHAVIOUR OF WATER DROPLETS ON POLYMERIC SURFACES UNDER THE INFLUENCE OF ELECTRIC FIELDS IN AN INCLINED TEST ARRANGEMENT

This paper investigates the influence of various parameters on the behaviour of water droplets on polymeric surfaces under electric fields. An inclined plane test was carried out to understand the droplet behaviour in strong electric field. Parameters, such as water droplet conductivity, droplet volume, polymeric surface roughness and droplet positioning with respect to the electrodes were studied. The flashover voltage is affected by all aforementioned parameters. The droplet positioning is in some cases more vital than the droplet volume. K e y w o r d s: water droplet, polymeric surface, hydrophobicity, partial discharges, local arcs
Explorations in the Derivation of Semantic Representations from Word Co-occurrence Statistics

Recent work has demonstrated that counts of which other words co-occur with a word of interest can reflect interesting properties of that word. We have studied aspects of this kind of methodology by systematically examining the effects of different combinations of parameters used in the preparation of co-occurrence statistics. Several psychologically relevant evaluation measures are used. We have found that successful performance on the evaluation tasks depends on the correct selection of parameters such as window size and distance metric.
Electrophysiological properties of the membrane and acetylcholine receptor in developing rat and chick myotubes

Membrane properties of rat and chick myotubes in various stages of development were studied. Resting membrane potentials (Em) increased from -8 to -55 mV in both rat and chick as the myotubes developed from myoblasts to large multinucleated fibers. In the rat myotubes, this increase was not accompanied by significant changes in specific membrane resistivity or changes in Na+ and K+ ion distribution. Nor have we observed a significant electrogenic component to the resting Em of mature rat myotubes under normal circumstances. A progressive increase in the passive permeability of the membrane to K+ relative to Na+ ions has been observed which can account for the changes in Em with development. In contrast to the changes in the ionic selectivity of the membrane, we have found that the ionic selectivity of the ACh receptor of rat and chick myotubes remains constant during the same period of myotube development.
An Optimal Algorithm for Euclidean Shortest Paths in the Plane

We propose an optimal-time algorithm for a classical problem in plane computational geometry: computing a shortest path between two points in the presence of polygonal obstacles. Our algorithm runs in worst-case time O(n log n) and requires O(n log n) space, where n is the total number of vertices in the obstacle polygons. The algorithm is based on an efficient implementation of wavefront propagation among polygonal obstacles, and it actually computes a planar map encoding shortest paths from a fixed source point to all other points of the plane; the map can be used to answer single-source shortest path queries in O(log n) time. The time complexity of our algorithm is a significant improvement over all previously published results on the shortest path problem. Finally, we also discuss extensions to more general shortest path problems, involving nonpoint and multiple sources.
Re-analysis of previous orientation-dependent surround suppression schizophrenia studies

The key assumptions of the use of a ratio to adjust the numerator to control for a particular variable (denominator) are that the relationship between the denominator and numerator is linear and that it passes through the origin. To investigate these assumptions, we performed regressions of orthogonal and parallel surround thresholds against no-surround thresholds2. As shown in Fig. R1 (left column) below, the relationships do appear to be linear but the y -intercept is consistently below zero.
Extending XCS with Cyclic Graphs for Scalability on Complex Boolean Problems

A main research direction in the field of evolutionary machine learning is to develop a scalable classifier system to solve high-dimensional problems. Recently work has begun on autonomously reusing learned building blocks of knowledge to scale from low-dimensional problems to high-dimensional ones. An XCS-based classifier system, known as XCSCFC, has been shown to be scalable, through the addition of expression tree–like code fragments, to a limit beyond standard learning classifier systems. XCSCFC is especially beneficial if the target problem can be divided into a hierarchy of subproblems and each of them is solvable in a bottom-up fashion. However, if the hierarchy of subproblems is too deep, then XCSCFC becomes impractical because of the needed computational time and thus eventually hits a limit in problem size. A limitation in this technique is the lack of a cyclic representation, which is inherent in finite state machines (FSMs). However, the evolution of FSMs is a hard task owing to the combinatorially large number of possible states, connections, and interaction. Usually this requires supervised learning to minimize inappropriate FSMs, which for high-dimensional problems necessitates subsampling or incremental testing. To avoid these constraints, this work introduces a state-machine-based encoding scheme into XCS for the first time, termed XCSSMA. The proposed system has been tested on six complex Boolean problem domains: multiplexer, majority-on, carry, even-parity, count ones, and digital design verification problems. The proposed approach outperforms XCSCFA (an XCS that computes actions) and XCSF (an XCS that computes predictions) in three of the six problem domains, while the performance in others is similar. In addition, XCSSMA evolved, for the first time, compact and human readable general classifiers (i.e., solving any n-bit problems) for the even-parity and carry problem domains, demonstrating its ability to produce scalable solutions using a cyclic representation.
A Genomic Portrait of Haplotype Diversity and Signatures of Selection in Indigenous Southern African Populations

We report a study of genome-wide, dense SNP (∼900K) and copy number polymorphism data of indigenous southern Africans. We demonstrate the genetic contribution to southern and eastern African populations, which involved admixture between indigenous San, Niger-Congo-speaking and populations of Eurasian ancestry. This finding illustrates the need to account for stratification in genome-wide association studies, and that admixture mapping would likely be a successful approach in these populations. We developed a strategy to detect the signature of selection prior to and following putative admixture events. Several genomic regions show an unusual excess of Niger-Kordofanian, and unusual deficiency of both San and Eurasian ancestry, which were considered the footprints of selection after population admixture. Several SNPs with strong allele frequency differences were observed predominantly between the admixed indigenous southern African populations, and their ancestral Eurasian populations. Interestingly, many candidate genes, which were identified within the genomic regions showing signals for selection, were associated with southern African-specific high-risk, mostly communicable diseases, such as malaria, influenza, tuberculosis, and human immunodeficiency virus/AIDs. This observation suggests a potentially important role that these genes might have played in adapting to the environment. Additionally, our analyses of haplotype structure, linkage disequilibrium, recombination, copy number variation and genome-wide admixture highlight, and support the unique position of San relative to both African and non-African populations. This study contributes to a better understanding of population ancestry and selection in south-eastern African populations; and the data and results obtained will support research into the genetic contributions to infectious as well as non-communicable diseases in the region.
Complete Protection from Repeated Vaginal Simian-Human Immunodeficiency Virus Exposures in Macaques by a Topical Gel Containing Tenofovir Alone or with Emtricitabine

ABSTRACT New-generation gels that deliver potent antiretroviral drugs against human immunodeficiency virus type 1 have renewed hopes for topical prophylaxis as a prevention strategy. Previous preclinical research with monkey models suggested that high concentrations and drug combinations are needed for high efficacy. We evaluated two long-acting reverse transcriptase inhibitors, tenofovir (TFV) and emtricitabine (FTC), by using a twice-weekly repeat challenge macaque model and showed that a preexposure vaginal application of gel with 1% TFV alone or in combination with 5% FTC fully protected macaques from a total of 20 exposures to simian-human immunodeficiency virus SF162p3. FTC and TFV were detected in plasma 30 min after vaginal application, suggesting rapid absorption. FTC was detected more frequently than TFV and showed higher levels, reflecting the fivefold-higher concentration of this drug than of TFV. Two of 12 repeatedly exposed but protected macaques showed limited T-cell priming, which did not induce resistance to infection when macaques were rechallenged. Thus, single drugs with durable antiviral activity can provide highly effective topical prophylaxis and overcome the need for noncoital use or for drug combinations which are more complex and costly to formulate and approve.
Beyond the Status Quo: A Role for Beta Oscillations in Endogenous Content (Re)Activation

Abstract Among the rhythms of the brain, oscillations in the beta frequency range (∼13–30 Hz) have been considered the most enigmatic. Traditionally associated with sensorimotor functions, beta oscillations have recently become more broadly implicated in top-down processing, long-range communication, and preservation of the current brain state. Here, we extend and refine these views based on accumulating new findings of content-specific beta-synchronization during endogenous information processing in working memory (WM) and decision making. We characterize such content-specific beta activity as short-lived, flexible network dynamics supporting the endogenous (re)activation of cortical representations. Specifically, we suggest that beta-mediated ensemble formation within and between cortical areas may awake, rather than merely preserve, an endogenous cognitive set in the service of current task demands. This proposal accommodates key aspects of content-specific beta modulations in monkeys and humans, integrates with timely computational models, and outlines a functional role for beta that fits its transient temporal characteristics.
Applied Physics Reviews Nanoscale Thermal Transport. Ii. 2003–2012

A diverse spectrum of technology drivers such as improved thermal barriers, higher efficiency thermoelectric energy conversion, phase-change memory, heat-assisted magnetic recording, thermal management of nanoscale electronics, and nanoparticles for thermal medical therapies are motivating studies of the applied physics of thermal transport at the nanoscale. This review emphasizes developments in experiment, theory, and computation in the past ten years and summarizes the present status of the field. Interfaces become increasingly important on small length scales. Research during the past decade has extended studies of interfaces between simple metals and inorganic crystals to interfaces with molecular materials and liquids with systematic control of interface chemistry and physics. At separations on the order of $1 nm, the science of radiative transport through nanoscale gaps overlaps with thermal conduction by the coupling of electronic and vibrational excitations across weakly bonded or rough interfaces between materials. Major advances in the physics of phonons include first principles calculation of the phonon lifetimes of simple crystals and application of the predicted scattering rates in parameter-free calculations of the thermal conductivity. Progress in the control of thermal transport at the nanoscale is critical to continued advances in the density of information that can be stored in phase change memory devices and new generations of magnetic storage that will use highly localized heat sources to reduce the coercivity of magnetic media. Ultralow thermal conductivity—thermal conductivity below the conventionally predicted minimum thermal conductivity—has been observed in nanolaminates and disordered crystals with strong anisotropy. Advances in metrology by time-domain thermoreflectance have made measurements of the thermal conductivity of a thin layer with micron-scale spatial resolution relatively routine. Scanning thermal microscopy and thermal analysis using proximal probes has achieved spatial resolution of 10 nm, temperature precision of 50 mK, sensitivity to heat flows of 10 pW, and the capability for thermal analysis of sub-femtogram samples. V C 2014 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.
Ability of mothers to assess the presence of fever in their children: implication for the treatment of fever under the IMCI guidelines.

BACKGROUND Fever is a common reason for seeking medical attention, with febrile illnesses accounting for 10% to 20% of pediatric visits to emergency departments. A history of fever or presence of fever by palpation or measured temperature is required on the Integrated Management of Childhood Illnesses (IMCI) algorithms as a reason for the assessment of fever, which will lead to specific classifications that are linked to treatment protocols. Therefore, the WHO and its partners assume that mothers are able to assess their children for the presence of fever. OBJECTIVES To evaluate the ability of mothers to determine the presence of fever in their children by tactile examination of their children. METHODS We prospectively studied 126 mother-child pairs attending the pediatric outpatient clinic of Ahmadu Bello University Teaching Hospital (ABUTH). Mothers of children 2 months to 5 years of age who mentioned fever as part of the presenting complaints were studied using a structured questionnaire regarding their children's illness, temperature status and their educational level. RESULTS A total of 126 mother-child pairs were studied, of which 44 (34.9%) of the mothers had had their education extended to secondary school level and only 15 (11.9%) had their education extended to a tertiary level. Fever was present in 82 (65.1%) of the children when their temperatures were determined by thermometer. The mothers correctly identified 79 (sensitivity of 96.3%) of the children who were truly febrile and 19 (specificity of 43.2%) of those who were truly nonfebrile. The predictive value of a positive test was 76.0%, and the predictive value of a negative test was 86.4%. CONCLUSION The results showed that mothers in our environment, as has been observed in other parts of the world, are able to correctly assess the presence or absence of fever in their children.