Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of guanidinoacetic acid supplementation on live performance, meat quality, pectoral myopathies and blood parameters of male broilers fed corn‐based diets with or without poultry by‐products

ABSTRACT Creatine is a nitrogenous compound naturally occurring in animal tissues and is obtained from dietary animal protein or de novo synthesis from guanidinoacetic acid (GAA). The dietary supply of this semi‐essential nutrient could be adversely compromised when feeding purely vegetable‐based diets. The objective of this experiment was to evaluate the effects of GAA supplementation in broilers fed corn‐based diets with or without the inclusion of poultry by‐products (PBP) on live performance, carcass and cut up yields, meat quality, pectoral muscle myopathies, differential blood count, blood clinical chemistry, serum GAA and its metabolites. The treatments consisted of PBP inclusion in the diets at 0 and 5%, with or without GAA supplementation (0 or 0.06%). A total of 1,280 one‐d‐old male Ross 708 broiler chicks were randomly placed in 64 floor pens with 16 replicates per treatment combination. At 0, 14, 35, 48, and 55 d, pen BW and feed intake were recorded. BW gain and FCR were calculated at the end of each phase. Individual BW was obtained at 55 d and one broiler per pen was selected for blood collection. Additionally, four broilers per pen were selected (including the chicken for blood collection) for processing. Data were analyzed as a randomized complete block design in a 2 × 2 factorial arrangement with PBP and GAA supplementation as main effects. An improvement (P < 0.05) on FCR of 0.019 (g:g) was detected at 55 d due to GAA supplementation. The probability of having breast meat with low severity of wooden breast (score 2) was increased (P < 0.05) by GAA inclusion in diets without PBP. An interaction effect (P < 0.05) was detected on GAA concentration in blood. The supplementation with GAA and PBP inclusion resulted in higher (P < 0.05) GAA serum concentration. Generally, meat quality parameters were not affected by GAA. In conclusion, GAA supplementation improved FCR regardless of dietary PBP and reduced wooden breast severity by increasing score 2 in diets without PBP.
The gas content of peculiar galaxies: Strongly interacting systems

A study of the gas content in 1038 interacting galaxies, essentially selected from Arp, Arp & Madore, Vorontsov-Velyaminov catalogues and some of the published literature, is presented here. The data on the interstellar medium have been extracted from a number of sources in the literature and compared with a sample of 1916 normal galaxies. The mean values for each of the different ISM tracers (FIR, 21 cm, CO lines, X-ray) have been estimated by means of survival analysis techniques, in order to take into account the presence of upper limits. From the data it appears that interacting galaxies have a higher gas content than normal ones. Galaxies classified as ellipticals have both a dust and gas content one order of magni- tude higher than normal. Spirals have in most part a normal dust and HI content but an higher molecular gas mass. The X-ray luminosity also appears higher than that of normal galaxies of same morphological type, both including or excluding AGNs. We considered the alternative possibilities that the molecular gas excess may derive from the existence of tidal torques which produce gas infall from the surrounding regions or from a different metallicity which affects the X conversion factor between the observed CO line luminosity and the H2 calculated mass. According to our tests, it appears that interacting galaxies possess a higher molecular mass than normal galaxies but with a similar star formation efficiency.
Distribution of ∆9‐Tetrahydrocannabinol and 11‐Nor‐9‐Carboxy‐∆9‐Tetrahydrocannabinol Acid in Postmortem Biological Fluids and Tissues From Pilots Fatally Injured in Aviation Accidents

Little is known of the postmortem distribution of ∆9‐tetrahydrocannabinol (THC) and its major metabolite, 11‐nor‐9‐carboxy‐∆9‐tetrahydrocannabinol (THCCOOH). Data from 55 pilots involved in fatal aviation accidents are presented in this study. Gas chromatography/mass spectrometry analysis obtained mean THC concentrations in blood from multiple sites, liver, lung, and kidney of 15.6 ng/mL, 92.4 ng/g, 766.0 ng/g, 44.1 ng/g and mean THCCOOH concentrations of 35.9 ng/mL, 322.4 ng/g, 42.6 ng/g, 138.5 ng/g, respectively. Heart THC concentrations (two cases) were 184.4 and 759.3 ng/g, and corresponding THCCOOH measured 11.0 and 95.9 ng/g, respectively. Muscle concentrations for THC (two cases) were 16.6 and 2.5 ng/g; corresponding THCCOOH, “confirmed positive” and 1.4 ng/g. The only brain tested in this study showed no THC detected and 2.9 ng/g THCCOOH, low concentrations that correlated with low values in other specimens from this case. This research emphasizes the need for postmortem cannabinoid testing and demonstrates the usefulness of a number of tissues, most notably lung, for these analyses.
MitoFish and MiFish Pipeline: A Mitochondrial Genome Database of Fish with an Analysis Pipeline for Environmental DNA Metabarcoding

Abstract Fish mitochondrial genome (mitogenome) data form a fundamental basis for revealing vertebrate evolution and hydrosphere ecology. Here, we report recent functional updates of MitoFish, which is a database of fish mitogenomes with a precise annotation pipeline MitoAnnotator. Most importantly, we describe implementation of MiFish pipeline for metabarcoding analysis of fish mitochondrial environmental DNA, which is a fast-emerging and powerful technology in fish studies. MitoFish, MitoAnnotator, and MiFish pipeline constitute a key platform for studies of fish evolution, ecology, and conservation, and are freely available at http://mitofish.aori. u-tokyo.ac. jp/ (last accessed April 7th, 2018).
Agonistic behaviour in juvenile southern rock lobster, Jasus edwardsii (Decapoda, Palinuridae): implications for developing aquaculture

Abstract The Southern rock lobster, Jasus edwardsii, is a temperate species of spiny lobster with established well managed fisheries in Australia and New Zealand. It has also been under consideration as a species with aquaculture potential. Agonistic behaviour has important consequences under aquaculture conditions that encompass direct effects, such as damage or death of protagonists, and indirect effects on growth that relate to resource access, principally food and refuge. This study aimed to identify and characterize behaviours and to make a preliminary investigation of their occurrence under tank culture. Juvenile Jasus edwardsii were examined in a flow-through seawater system using a remote video camera system. Twenty-nine behaviours were divided into three sub-groups: aggressive (11), avoidance (6) and others (12). Aggressive behaviours included attacks, pushing, lifting, clasping and carrying an opponent. Avoidance behaviours included moving away in a backwards-, forwards- or side-stepping motion as well as with more vigorous tail flips. These behaviours were components of twelve behavioural groups that described contact, attack and displacement between individuals. Activity was crepuscular with two clear peaks, one in the morning and the other in the evening. The occurrence of behavioural groups was not different between the morning and evening. The frequency of aggressive behaviours was not affected by changes made to stocking density or access to food. The implications of agonistic behaviours are discussed further in relation to developing aquaculture.
Fast Dynamic Binary Rewriting for flexible thread migration on shared-ISA heterogeneous MPSoCs

Heterogeneous MPSoCs where different types of cores share a baseline ISA but implement different operational accelerators combine programmability with flexible customization. They hold promise for high performance under power and area limitations. However, transparent binary execution and dynamic scheduling is hard on those platforms. The stateof-the-art approach for transparent accelerated execution is fault-and-migrate (FAM): when a thread executes an accelerating instruction unavailable on the host core, it is forcibly migrated to an accelerating core which implements the instruction natively. Unfortunately, this approach prohibits dynamic scheduling through flexible thread migration, which is essential to any asymmetric platform for efficient utilization of heterogeneous resources. We present two distinct binary-level techniques - Dynamic Binary Rewriting (DBR) and Dynamic Binary Translation (DBT) - which enable selective acceleration, while preserving transparent thread execution and migration, to any core in the system, at any point in time. DBR rewrites binary code to exploit any accelerating instructions available in the host core. DBT implements a-fault-and-rewrite scheme, which sets up trampolines to emulation routines for these accelerating instructions which are not available on the host core. Both methods customize binary code on demand, enabling flexible migration. We evaluate the overhead of DBR and DBT against FAM on a real hardware shared-ISA MPSoC prototype. Experiments with single-thread programs show flexible migration is possible with manageable overhead. We measure the performance of our binary-level techniques by artificially triggering periodic thread migration between a Base and an accelerating (ACC) core. Periodic migration, without aiming for optimized scheduling, results in an average slowdown of about 40% under DBR or about 10% under DBT, compared to FAM driven scheduling. We also show results for a speedup proportional dynamic scheduler, enabled by our techniques, using multi-program workloads. In this case, up to 50% faster execution times can be achieved by leveraging flexible thread migration.
An Examination of the Psychology of Working Theory With Racially and Ethnically Diverse Employed Adults

The present study tested key tenets of the Psychology of Working Theory (PWT) in a sample of 526 racially and ethnically diverse employed adults. The authors investigated how economic resources and marginalization predicted decent work through experiences of work volition and career adaptability. Support for the hypotheses was mixed. There was a direct, negative relation between marginalization and decent work; a direct, positive relation between economic resources and work volition; and a direct, negative relation between marginalization and work volition. There was a positive relation between work volition and career adaptability as well as with decent work. Work volition was also found to significantly mediate the relations between marginalization and economic resources to decent work. These results suggest that the primary reason why greater economic resources and lower experiences of marginalization predict engaging in decent work is attributable to an increased sense of choice in one’s career decision making. Results suggest the need for further investigation using the PWT to understand how racially and ethnically diverse employed adults secure decent work. Practical implications are discussed.
Effects of empathic and positive communication in healthcare consultations: a systematic review and meta-analysis

Background Practitioners who enhance how they express empathy and create positive expectations of benefit could improve patient outcomes. However, the evidence in this area has not been recently synthesised. Objective To estimate the effects of empathy and expectations interventions for any clinical condition. Design Systematic review and meta-analysis of randomised trials. Data sources Six databases from inception to August 2017. Study selection Randomised trials of empathy or expectations interventions in any clinical setting with patients aged 12 years or older. Review methods Two reviewers independently screened citations, extracted data, assessed risk of bias and graded quality of evidence using GRADE. Random effects model was used for meta-analysis. Results We identified 28 eligible (n = 6017). In seven trials, empathic consultations improved pain, anxiety and satisfaction by a small amount (standardised mean difference −0.18 [95% confidence interval −0.32 to −0.03]). Twenty-two trials tested the effects of positive expectations. Eighteen of these (n = 2014) reported psychological outcomes (mostly pain) and showed a modest benefit (standardised mean difference −0.43 [95% confidence interval −0.65 to −0.21]); 11 (n = 1790) reported physical outcomes (including bronchial function/ length of hospital stay) and showed a small benefit (standardised mean difference −0.18 [95% confidence interval −0.32 to −0.05]). Within 11 trials (n = 2706) assessing harms, there was no evidence of adverse effects (odds ratio 1.04; 95% confidence interval 0.67 to 1.63). The risk of bias was low. The main limitations were difficulties in blinding and high heterogeneity for some comparisons. Conclusions Greater practitioner empathy or communication of positive messages can have small patient benefits for a range of clinical conditions, especially pain. Protocol registration Cochrane Database of Systematic Reviews (protocol) DOI: 10.1002/14651858.CD011934. pub2.
Artificial neural network modelling for organic and total nitrogen removal of aerobic granulation under steady-state condition

ABSTRACT Aerobic granulation is a recent technology with high level of complexity and sensitivity to environmental and operational conditions. Artificial neural networks (ANNs), computational tools capable of describing complex non-linear systems, are the best fit to simulate aerobic granular bioreactors. In this study, two feedforward backpropagation ANN models were developed to predict chemical oxygen demand (Model I) and total nitrogen removal efficiencies (Model II) of aerobic granulation technology under steady-state condition. Fundamentals of ANN models and the steps to create them were briefly reviewed. The models were respectively fed with 205 and 136 data points collected from laboratory-, pilot-, and full-scale studies on aerobic granulation technology reported in the literature. Initially, 60%, 20%, and 20%, and 80%, 10%, and 10% of the points in the corresponding datasets were randomly chosen and used for training, testing, and validation of Model I, and Model II, respectively. Overall coefficient of determination (R2) value and mean squared error (MSE) of the two models were initially 0.49 and 15.5, and 0.37 and 408, respectively. To improve the model performance, two data division methods were used. While one method is generic and potentially applicable to other fields, the other can only be applied to modelling the performance of aerobic granular reactors. R2 value and MSE were improved to 0.90 and 2.54, and 0.81 and 121.56, respectively, after applying the new data division methods. The results demonstrated that ANN-based models were capable simulation approach to predict a complicated process like aerobic granulation. GRAPHICAL ABSTRACT
Flexible propulsors in ground effect

We present experimental evidence for the hydrodynamic benefits of swimming ‘in ground effect’, that is, near a solid boundary. This situation is common to fish that swim near the substrate, especially those that are dorsoventrally compressed, such as batoids and flatfishes. To investigate flexible propulsors in ground effect, we conduct force measurements and particle image velocimetry on flexible rectangular panels actuated at their leading edge near the wall of a water channel. For a given actuation mode, the panels swim faster near the channel wall while maintaining the same propulsive economy. In conditions producing net thrust, panels produce more thrust near the ground. When operating in resonance, swimming near the ground can also increase propulsive efficiency. Finally, the ground can act to suppress three-dimensional modes, thereby increasing thrust and propulsive efficiency. The planform considered here is non-biological, but the hydrodynamic benefits are likely to apply to more complex geometries, especially those where broad flexible propulsors are involved such as fish bodies and fins. Such fish could produce more thrust by swimming near the ground, and in some cases do so more efficiently.
Identification of four plasma microRNAs as potential biomarkers in the diagnosis of male lung squamous cell carcinoma patients in China

Dysregulated microRNAs (miRNAs) in the plasma of patients with lung squamous cell carcinoma (LSCC) might serve as biomarkers for LSCC diagnosis. The expression of miRNAs was performed using quantitative reverse transcription–polymerase chain reaction (qRT‐PCR) on the basis of Exiqon panels in the initial screening phase including three male LSCC pool samples and one normal control (NC) pool sample (per 10 samples were pooled as one pool sample). After the training (32 LSCC vs. 31 NCs), the testing (55 LSCC vs. 55 NCs), and the external validation (15 LSCC vs. 15 NCs) stages via qRT‐PCR, a four‐miRNA signature (miR‐181a‐5p, miR‐21‐5p, miR‐106a‐5p, and miR‐93‐5p) was identified for LSCC detection. Areas under the receiver operating characteristic (ROC) curve (AUC) of the four‐miRNA panel for the training, the testing, and the external validation phases were 0.795, 0.827, and 0.914, respectively. Then, the four miRNAs were explored in LSCC tissue samples (23 LSCC vs. 23 NCs), and their expression was significantly up‐regulated. However, none of the four miRNAs found significantly up‐regulated in plasma exosomes expect miR‐93‐5p with borderline significance (16 LSCC vs. 16 NCs). In summary, our study established a four‐miRNA peripheral plasma signature, which contributed to diagnosing male LSCC patients in China to a certain degree.
Evaluation of calciotropic hormones in cats with odontoclastic resorptive lesions.

OBJECTIVE To assess associations between epidemiologic and laboratory variables and calciotropic hormones in cats with odontoclastic resorptive lesions (ORLs). ANIMALS 182 client-owned cats older than 1 year of age with oral disease. PROCEDURE Information on medical history, behavior, living environment, and feeding management was assessed by use of a questionnaire. After induction of general anesthesia, oral examination was performed following standardized protocols and included dental probing and full-mouth radiography. Laboratory analyses included evaluation of FeLV-FIV status, serum biochemical analyses, CBC, urinalysis, and serum concentrations of intact parathyroid hormone (iPTH), parathyroid hormone-related peptide (PTHrP), 25-hydroxyvitamin D (25-OHD), free thyroxine (fT4), and ionized calcium (iCa). RESULTS ORLs were identified in 72.5% of cats. Mandibular third premolars were the most commonly affected teeth. Cats with ORLs were significantly older (mean, 9.2 years) than cats without ORLs (mean, 6.6 years). Multivariate logistic regression analysis revealed that 25-OHD, urine specific gravity, jaw-opening reflex on probing, and missing teeth were significant variables, even after accounting for age. Cats with ORLs had significantly higher mean serum concentration of 25-OHD (112.4 nmol/L) and significantly lower mean urine specific gravity (1.0263), compared with cats without ORLs (89.8 nmol/L and 1.0366, respectively). CONCLUSIONS AND CLINICAL RELEVANCE Results did not indicate associations between iPTH, PTHrP, or fT4 and development of ORLs. In affected cats, the importance of high serum 25-OHD and low urine specific gravity has not been determined.
The impact of attachment distress on affect-centered mentalization: An experimental study in psychosomatic patients and healthy adults

Introduction We investigated the impact of attachment distress on affect-centered mentalization in a clinical and a non-clinical sample, comparing mentalization in a baseline condition to mentalization under a condition of attachment distress. Methods The sample consisted of 127 adults who underwent inpatient psychosomatic treatment, and 34 mentally healthy adults. Affect-centered mentalization was assessed by analyzing participants’ narratives on interpersonal situations in a baseline condition with the Levels of Emotional Awareness Scale (LEAS), and an experimental condition inducing attachment distress with the Adult Attachment Projective Picture System (AAP). Unlike the LEAS, the AAP is specifically designed to trigger attachment distress. In both conditions, the narratives were evaluated using the LEAS scoring system. Additionally, we assessed the impact of childhood trauma on affect-centered mentalization with the Childhood Trauma Questionnaire (CTQ). Results While the non-clinical sample displayed the same level of affect-centered mentalization in both conditions, the majority of the clinical sample reached higher scores in the attachment distress condition. There was no strong relationship between reported trauma and mentalization scores. Discussion Our findings lend strong empirical support to the assumption that affect-centered mentalization is modulated by attachment-related distress. Several possible explanations for the differences between and within the clinical and the non-clinical sample are discussed.
Modification of fuel performance code to evaluate iron-based alloy behavior under LOCA scenario

Accident tolerant fuels (ATF) has been studied since the Fukushima Daiichi accident in the research efforts to develop new materials which under accident scenarios could maintain the fuel rod integrity for a longer period compared to the cladding and fuel system usually utilized in Pressurized Water Reactors (PWR). The efforts have been focused on new materials applied as cladding, then iron-base alloys appear as a possible candidate. The aim of this paper is to implement modifications in a fuel performance code to evaluate the behavior of iron-based alloys under Loss-of-Coolant Accident (LOCA) scenario. For this, initially the properties related to the thermal and mechanical behavior of iron-based alloys were obtained from the literature, appropriately adapted and introduced in the fuel performance code subroutines. The adopted approach was step by step modifications, where different versions of the code were created. The assessment of the implemented modification was carried out simulating an experiment available in the open literature (IFA-650.5) related to zirconium-based alloy fuel rods submitted to LOCA conditions. The obtained results for the iron-based alloy were compared to those obtained using the regular version of the fuel performance code for zircaloy-4. The obtained results have shown that the most important properties to be changed are those from the subroutines related to the mechanical properties of the cladding. The results obtained have shown that the burst is observed at a longer time for fuel rods with iron-based alloy, indicating the potentiality of this material to be used as cladding with ATF purposes.
Asset Pricing for the Shortfall Averse ∗

Compare the utility from consuming a certain amount under two circumstances which vary by the levels of past historical consumptions. This papers premise is that the higher past historical consumption, the lower is the utility from current consumption. The paper and its companion, GHR, extend standard models of utility from dynamic consumption to have this property. Here and in GHR, the behavior of the optimizing consumer/investor takes into consideration the eﬀect of current choices on the utility of future consumption. Assuming a representative agent framework this paper derives implications for the term structure of real interest rates and for equity pricing which generally are consistent with US data