Miracle-dz/UniFAR-FTUs huggingface dataset:
J O U R N a L O F Veterinary Science Case Report Autologous Conditioned Plasma as Therapy of Tendon and Ligament Lesions in Seven Horses

This case report describes the intralesional application of autologous conditioned plasma (ACP) in seven horses as treatment of severe tendinitis of the superficial digital flexor tendon, deep digital flexor tendon, or desmitis of the inferior check ligament. Follow-up data of the horses revealed a positive outcome in 10 to 13 months post injury. All horses treated with ACP were either performing in their previous work-load or were back in full training. Further studies with long-term follow-up will have to be performed to support these clinical intermediate-term observations. Tendon and ligament injuries are among the most common musculoskeletal injuries and contribute to a considerable economic loss for the equine industry [5,8,10,14]. New regenerative therapies are thought to harness the animal's ability to repair the injury site and to reduce scar tissue formation [6]. Seven horses of different breeds − 3 mares, 4 geldings, aged 4 to 12 years, used as sport and/or pleasure riding horses − were included in this study. The horses were presented at the clinic and met the following criteria: acute severe tendinitis of the superficial digital flexor tendon (SDFT) or deep digital flexor tendon (DDFT), or acute desmitis of the inferior check ligament (ICL) of one or both forelimbs; no treatment prior to admission; and otherwise normal results of the clinical examination. All horses were subjected to a general examination with whole blood analysis and a lameness examination. Tendons and ligaments were evaluated ultrasonographically and the damaged tendon/ ligament areas were documented, with evaluation of the following parameters: the cross sectional area (CSA; cm 2), the percentage of the maximum injury zone compared to the size of a healthy tendon/ligament (%MIZ), the echogenicity score (ES) of the lesion (range: 0 to 4), and the fibre alignment score (FAS: range 0 to 4). The FAS was determined in the longitudinal view of the lesion [12]. Autologous conditioned plasma (ACP) therapy was performed in each horse (n = 7) at the day of presentation at the clinic (D0), and also after a 2-week interval (D1) in horse SDFT 2. Autologous conditioned plasma was prepared using a 15 mL ACP double syringe (Arthrex GmbH, Germany) according to the manufacturer's instructions. An average of 5 mL of ACP was obtained from every 15 mL syringe. At D0, a 1 mL fraction of the ACP was analyzed for hematocrit (Hct), platelets and white blood cell (WBC) count. After preparation the ACP was …
Why we can not see the curvature of the quantum state space

A new type of gauge quantum theory (superrelativity) has been proposed. This differs from ordinary gauge theories in sense that the affine connection of our theory is constructed from first derivatives of the Fubini-Study metric tensor. That is we have not merely analogy with general relativity but this construction should presumably provide a unification of general relativity and quantum theory. Here we shall discuss the physical meaning of metric properties of the projective Hilbert space and manifestation of its nontrivial physical character.
The Collective Model of Household Consumption: A Nonparametric Characterization

We provide a nonparametric characterization of a general collective model for household consumption, which includes externalities and public consumption. Next, we establish testable necessary and sufficient conditions for data consistency with collective rationality that only include observed price and quantity information. These conditions have a similar structure as the generalized axiom of revealed preference for the unitary model, which is convenient from a testing point of view. In addition, we derive the minimum number of goods and observations that enable the rejection of collectively rational household behavior. Copyright The Econometric Society 2007. (This abstract was borrowed from another version of this item.)
A test of faith? : religious diversity and accommodation in the European workplace

Religious interests in the European workplace : different perspectives / Lucy Vickers -- Religious accommodation in the workplace: improving the legal reasoning of the European Court of Human Rights / Saila Ouald Chaib -- A critical appraisal of the margin of appreciation left to states pertaining to "church-state relations" under the jurisprudence of the European Court of Human Rights / Kristin Henrard -- Beyond Lautsi : an alternative approach to limiting the government's ability to display religious symbols in the public workplace / Hans-Martien ten Napel -- Accommodation of religion and sex equality in the workplace under the EU equality directives : a double bind for the European Court of Justice / Titia Loenen -- Silence is golden? : charting the intersections of speech and direct discrimination under EU law with a special focus on racial and religious discrimination in recruitment / Jogchum Vrielink -- Religious-ethos employers and other expressive employers under European and Belgian employment law / Yves Stox -- Religion in the public and private Turkish workplace : the approach of the Turkish judiciary / Mine Yildirim -- The practice of religion in the French public and private workplace : in search of an elusive balance / Rim-Sarah Alouane -- Jewish women in the Belgian workplace : an anthropological perspective / Efrat Tzadik -- Muslim women made redundant : unintended signals in Belgian and Dutch case law on religious dress in private sector employment and unemployment / Katayoun Alidadi -- Reasonable accommodation as a tool to manage religious diversity in the workplace : what about the "transposability" of an American concept into the French secular context? / Gabrielle Caceres -- A perspective from across the Atlantic : the "faith at work" movement in the United States : a new management model for religious diversity in the European workplace? / Amandine Barb -- Religion, diversity and the workplace : what role for the law? / Julie Ringelheim
Molecular and Epidemiological Trend of Sapovirus, and Astrovirus Infection in Japan

Surveillance for invasive pneumococcal disease during 2000–2005 in a population of children who received 7-valent pneu-mococcal conjugate vaccine. Pediatr Infect Dis J 2007;26:771–7. 6. Cherian T. WHO expert consultation on serotype composition of pneumococcal conjugate vaccines for use in resource-Human sapoviruses (SVs), formerly known as Sapporo-like viruses, are single-stranded positive-sense RNA viruses in the family Caliciviridae, which have been found to cause outbreaks of gastroenteritis in children's hospitals and mental health care facilities [1, 2]. SVs can be divided into five genogroups (GI to GV), among which, GI, GII, GIV and GV are identified within humans [1]. Human astroviruses (HAstVs) are non-enveloped, single-stranded positive-sense RNA viruses in the family Astroviridae, which may be the second most common cause of viral gastroenteritis in young children [3, 4]. A total of 628 fecal specimens were collected from infants and children with acute gastroenteritis in five
Sell the news? A news-driven model of the stock market

We attempt to explain stock market dynamics in terms of the interaction among three variables: market price, investor opinion and information flow. We propose a framework for such interaction upon which are based two models of stock market dynamics: the model for empirical study and its extended version for theoretical study. We demonstrate that these models replicate observed stock market behavior on all relevant timescales (from days to years) reasonably well. Using the models, we obtain and discuss a number of results that pose implications for current market theory and offer potential practical applications.
STRESS AND BOUNDARY EFFECTS ON ANTICIPATORY AND PRESERVATORY NASAL AIRFLOW

The present study examined the effects of boundary strength and stress on nasal coarticulation with neighboring segments. Acoustic and nasal airflow data were recorded from four speakers as they produced intervocalic fricative-nasal and nasalfricative sequences that spanned a word-internal boundary or a word boundary under two different stress conditions. Although neither stress nor boundary affected preservatory nasal airflow, tautosyllabic stress was associated with increased anticipatory nasal airflow within a word, but not at the a word boundary where coarticulation decreased or stayed the same. The interaction between boundary strength and stress was attributed to condition-dependent differences in the relative durations of individual segments. Overall, the study suggests that stress-induced lengthening of a velar gesture results in the leftward spread of nasality if adjacent segments are not also substantially lengthened by prosodic factors.
Estimation accuracy of a reduced lead system during simulated ischemia

In this study we investigate the influence of ischemic events on the estimation accuracy of a reduced lead system based on leads I, II, V2 and V5. The estimation accuracy of this lead system has been assessed for generalized and patient specific lead derivation. Assessments have been performed on a piecewise homogenous torso model that has been used to simulated ischemic events of different size and location. The patient specific lead derivation approach achieved root mean squared error (RMSE) values of 4. 7μV, 24. 4μV, 4. 4μV and 2. 6μV for derived leads V1, V3, V4 and V6 when no ischemia was simulated. It was found that RMSE values for patient specific derived leads increased when ischemia was simulated. Median RMSE values calculated for each lead and across all simulated ischemic events were found to be 40. 0μV, 126. 7μV, 38. 2μV and 35. 1μV for derived leads V1, V3, V4 and V6. These values are comparable to the median RMSE values 52. 7μV, 141. 7μV, 46. 9μV and 20. 3μV for derived leads V1, V3, V4 and V6 that were found when generalized lead derivation was performed for all ischemic events.
Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.

AIMS Cells have developed quality control systems for protection against proteotoxicity. Misfolded and aggregation-prone proteins, which are behind the initiation and progression of many neurodegenerative diseases (ND), are known to challenge the proteostasis network of the cells. We aimed to explore the role of DNJ-27/ERdj5, an endoplasmic reticulum (ER)-resident thioredoxin protein required as a disulfide reductase for the degradation of misfolded proteins, in well-established Caenorhabditis elegans models of Alzheimer, Parkinson and Huntington diseases. RESULTS We demonstrate that DNJ-27 is an ER luminal protein and that its expression is induced upon ER stress via IRE-1/XBP-1. When dnj-27 expression is downregulated by RNA interference we find an increase in the aggregation and associated pathological phenotypes (paralysis and motility impairment) caused by human β-amyloid peptide (Aβ), α-synuclein (α-syn) and polyglutamine (polyQ) proteins. In turn, DNJ-27 overexpression ameliorates these deleterious phenotypes. Surprisingly, despite being an ER-resident protein, we show that dnj-27 downregulation alters cytoplasmic protein homeostasis and causes mitochondrial fragmentation. We further demonstrate that DNJ-27 overexpression substantially protects against the mitochondrial fragmentation caused by human Aβ and α-syn peptides in these worm models. INNOVATION We identify C. elegans dnj-27 as a novel protective gene for the toxicity associated with the expression of human Aβ, α-syn and polyQ proteins, implying a protective role of ERdj5 in Alzheimer, Parkinson and Huntington diseases. CONCLUSION Our data support a scenario where the levels of DNJ-27/ERdj5 in the ER impact cytoplasmic protein homeostasis and the integrity of the mitochondrial network which might underlie its protective effects in models of proteotoxicity associated to human ND.
Do automatic refactorings improve maintainability? An industrial case study

Refactoring is often treated as the main remedy against the unavoidable code erosion happening during software evolution. Studies show that refactoring is indeed an elemental part of the developers' arsenal. However, empirical studies about the impact of refactorings on software maintainability still did not reach a consensus. Moreover, most of these empirical investigations are carried out on open-source projects where distinguishing refactoring operations from other development activities is a challenge in itself. We had a chance to work together with several software development companies in a project where they got extra budget to improve their source code by performing refactoring operations. Taking advantage of this controlled environment, we collected a large amount of data during a refactoring phase where the developers used a (semi)automatic refactoring tool. By measuring the maintainability of the involved subject systems before and after the refactorings, we got valuable insights into the effect of these refactorings on large-scale industrial projects. All but one company, who applied a special refactoring strategy, achieved a maintainability improvement at the end of the refactoring phase, but even that one company suffered from the negative impact of only one type of refactoring.
From babbling towards the sound systems of English and French: a longitudinal two-case study

ABSTRACT The utterances of one French and one American infant at 0;5, 0;8, 0;11, and 1;2 were transcribed and acoustically analysed for syllable duration and vowel formant values. Both general and language-specific effects emerged in the longitudinal study. Initial similarities in the consonantal repertoires of both infants, increasing control in producing target F1 and F2 values, and developmental changes in babbling characteristics over time seem to reflect universal patterns. Yet the babbling of the infants differed in ways that appear to be due to differences in their language environments. Shifts in the infants' sound repertoires reflected phoneme frequencies in the adult languages. The English-learning infant produced more closed syllables, which is characteristic of English, than the French-learning infant. The French-learning infant tended to produce more regularly-timed nonfinal syllables and showed significantly more final-syllable lengthening (both characteristic of French) than the English-learning infant.
Vector-based Models of Semantic Composition

This paper proposes a framework for representing the meaning of phrases and sentences in vector space. Central to our approach is vector composition which we operationalize in terms of additive and multiplicative functions. Under this framework, we introduce a wide range of composition models which we evaluate empirically on a sentence similarity task. Experimental results demonstrate that the multiplicative models are superior to the additive alternatives when compared against human judgments.
Ownership structure, earnings management and acquiring firm post‐merger market performance : Evidence from Canada

Purpose - The purpose of this paper is to investigate the link between ownership structure, earnings management (EM) preceding mergers and acquisitions (M&A) and the acquiring firm's subsequent long-term market performance. Design/methodology/approach - The authors measure the magnitude of discretionary current accruals using two methodologies, that of Teoh Findings - It was found that firms using stock as a financing medium exhibit significant positive discretionary accruals during the year preceding the M&A and during the year of the acquisition. It was also documented that voting right concentration and control-enhancing mechanisms are not associated with any significant level of earnings management. Finally, a negative association was found between EM and abnormal stock returns over a three-year period following the acquisition. Research limitations/implications - These results suggest that the concentrated ownership alignment effect dominates the entrenchment motives and acts as a deterrent mechanism to prevent controlling shareholders from managing earnings in stock-financed M&A. Practical implications - The authors’ results highlight the importance of maintaining good legal and extra-legal protection of minority shareholders. Regulators can play an important role in preventing dominant shareholders from engaging in opportunistic EM in stock-financed M&A. Originality/value - The paper extends prior literature by taking a closer look at dominant shareholders’ motivations to manage earnings in stock-financed M&A. Large shareholders have strong incentives to manage earnings upward prior to stock-financed transactions to limit the dilution of their controlling position.
Fully Distributed Scrum: Replicating Local Productivity and Quality with Offshore Teams

Scrum was designed for hyperproductive teams where productivity increases by 5-10 times over industry averages and many collocated teams have achieved this effect. The question for this paper is whether distributed, offshored teams can consistently achieve the same level of performance. In particular, can a team establish a localized velocity and quality and then maintain or increase that velocity and quality when distributing teams across continents. Since 2006, Xebia (Netherlands) started localized projects with half Dutch and half Indian team members. After establishing localized hyperproductivity, they move the Indian members of the team to India and show the same velocity with fully distributed teams. After running XP engineering practices inside many distributed Scrum projects, Xebia has systematically productized a model for high performance, distributed, offshore teams with one of the lowest defect rates in the industry.
Person Re-identification Meets Image Search

For long time, person re-identification and image search are two separately studied tasks. However, for person re-identification, the effectiveness of local features and the "query-search" mode make it well posed for image search techniques. In the light of recent advances in image search, this paper proposes to treat person re-identification as an image search problem. Specifically, this paper claims two major contributions. 1) By designing an unsupervised Bag-of-Words representation, we are devoted to bridging the gap between the two tasks by integrating techniques from image search in person re-identification. We show that our system sets up an effective yet efficient baseline that is amenable to further supervised/unsupervised improvements. 2) We contribute a new high quality dataset which uses DPM detector and includes a number of distractor images. Our dataset reaches closer to realistic settings, and new perspectives are provided. Compared with approaches that rely on feature-feature match, our method is faster by over two orders of magnitude. Moreover, on three datasets, we report competitive results compared with the state-of-the-art methods.
Teacher and teacher assistant perceptions of their relationship

This qualitative research study examined teachers’ and teacher assistants’ perceptions of their working relationships. Three teachers and three teacher assistants reflected specifically on their work experiences and interactions with their job partners in their respective schools, as they worked to provide supports to students with a variety of behavioral, academic and medical needs. Two main questions guided this research: How did each participant describe their working relationship with his/her job partner? What factors were perceived as influential on a positive and effective working relationship? Thematic analysis of the qualitative interview data from the participants informed the generation of dominant themes. The role of administration, professional interaction, and personal attributes emerged as main factors influencing the teacher and teacher assistant relationship. The researcher provides a model for conceptualizing this relationship and suggests that professionalism is required of both parties in the relationship. The model of professionalism is supported by three main behaviors exhibited by people in the relationship: competence, collegiality, and clarity of role.
Mathematical modelling of flow through vascular networks: Implications for tumour-induced angiogenesis and chemotherapy strategies

Angiogenesis, the formation of blood vessels from a pre-existing vasculature, is a process whereby capillary sprouts are formed in response to externally supplied chemical stimuli. The sprouts then grow and develop, driven initially by endothelial cell migration, and organize themselves into a branched, connected network structure. Subsequent cell proliferation near the sprout-tip permits further extension of the capillary and ultimately completes the process. Angiogenesis occurs during embryogenesis, wound healing, arthritis and during the growth of solid tumours. In this paper we initially generate theoretical capillary networks (which are morphologically similar to those networks observed in vivo) using the discrete mathematical model of Anderson and Chaplain. This discrete model describes the formation of a capillary sprout network via endothelial cell migratory and proliferative responses to external chemical stimuli (tumour angiogenic factors, TAF) supplied by a nearby solid tumour, and also the endothelial cell interactions with the extracellular matrix.The main aim of this paper is to extend this work to examine fluid flow through these theoretical network structures. In order to achieve this we make use of flow modelling tools and techniques (specifically, flow through interconnected networks) from the field of petroleum engineering. Having modelled the flow of a basic fluid through our network, we then examine the effects of fluid viscosity, blood vessel size (i.e., diameter of the capillaries), and network structure/geometry, upon: (i) the rate of flow through the network; (ii) the amount of fluid present in the complete network at any one time; and (iii) the amount of fluid reaching the tumour. The incorporation of fluid flow through the generated vascular networks has highlighted issues that may have major implications for the study of nutrient supply to the tumour (blood/oxygen supply) and, more importantly, for the delivery of chemotherapeutic drugs to the tumour. Indeed, there are also implications for the delivery of anti-angiogenesis drugs to the network itself. Results clearly highlight the important roles played by the structure and morphology of the network, which is, in turn, linked to the size and geometry of the nearby tumour. The connectedness of the network, as measured by the number of loops formed in the network (the anastomosis density), is also found to be of primary significance. Moreover, under certain conditions, the results of our flow simulations show that an injected chemotherapy drug may bypass the tumour altogether.
Size rationalization and trade exposure in developing countries

Given the lack of direct evidence regarding industrial adjustment in response to trade liberalization, this paper tackles some very basic questions. Specifically, in LDCs, how is trade orientation correlated with the size distribution of plants and with plant-level labor productivity? It begins with a simple model that summarizes some effects of trade exposure on producer size and productive efficiency that have been stressed in the recent analytical and simulation literature. It then examines annual plant-level data from Chile and Colombia to determine whether these effects can be confirmed. The empirical results indicate that, over the long run, higher trade exposure is correlated with smaller plant sizes, controlling for industry and country effects. However, the mix of high versus low productivity plants is not strongly associated with trade exposure. Both of these findings cast doubt on the mechanisms linking trade, plant size, and productivity in a number of recent analytical and simulation studies.