Miracle-dz/UniFAR-FTUs huggingface dataset:
Chemical Abundances in an AGN Environment: X-Ray/UV Campaign on the Markarian 279 Outflow

We present the first reliable determination of chemical abundances in an active galactic nucleus (AGN) outflow. The abundances are extracted from the deep and simultaneous Far Ultraviolet Spectroscopic Explorer (FUSE) and Hubble Space Telescope (HST) STIS observations of Mrk 279. This data set is exceptional for its high signal-to-noise ratio, unblended doublet troughs, and little Galactic absorption contamination. These attributes allow us to solve for the velocity-dependent covering fraction and therefore obtain reliable column densities for many ionic species. For the first time, we have enough such column densities to simultaneously determine the ionization equilibrium and abundances in the flow. Our analysis uses the full spectral information embedded in these high-resolution data. Slicing a given trough into many independent outflow elements yields the extra constraints needed for a physically meaningful abundance determination. We find that relative to solar, the abundances in the Mrk 279 outflow are (linear scaling) carbon 2.2 ± 0.7, nitrogen 3.5 ± 1.1, and oxygen 1.6 ± 0.8. Our UV-based photoionization and abundance results are in good agreement with the independent analysis of the simultaneous Mrk 279 X-ray spectra. This is the best agreement between the UV and X-ray analyses of the same outflow to date.
Survey for Transiting Extrasolar Planets in Stellar Systems. III. A Limit on the Fraction of Stars with Planets in the Open Cluster NGC 1245

We analyze a 19 night photometric search for transiting extrasolar planets in the open cluster NGC 1245. An automated transit search algorithm with quantitative selection criteria finds six transit candidates; none are bona fide planetary transits. We characterize the survey detection probability via Monte Carlo injection and recovery of realistic limb-darkened transits. We use this to derive upper limits on the fraction of cluster members with close-in Jupiter radii, RJ, companions. The survey sample contains ∼870 cluster members, and we calculate 95% confidence upper limits on the fraction of these stars with planets by assuming that the planets have an even logarithmic distribution in semimajor axis over the Hot Jupiter (HJ; 3.0 < P day-1 < 9.0) and Very Hot Jupiter (VHJ; 1.0 < P day-1 < 3.0) period ranges. For 1.5RJ companions we limit the fraction of cluster members with companions to <6.4% and <52% for VHJ and HJ companions, respectively. For 1.0RJ companions we find that <24% have VHJ companions. We do not reach the sensitivity to place any meaningful constraints on 1.0RJ HJ companions. From a careful analysis of the random and systematic errors of the calculation, we show that the derived upper limits contain a +13%/ - 7% relative error. For photometric noise and weather properties similar to those of this survey, observing NGC 1245 twice as long results in a tighter constraint on HJ companions than observing an additional cluster of richness similar to that of NGC 1245 for the same length of time as this survey. If 1% of stars have 1.5RJ HJ companions (as measured in radial velocity surveys), we expect to detect one planet for every 5000 dwarf stars observed for a month. To reach an ∼2% upper limit on the fraction of stars with 1.5RJ companions in the 3.0 < P day-1 < 9.0 range, we conclude that a total sample size of ∼7400 dwarf stars observed for at least a month will be needed. Results for 1.0RJ companions, without substantial improvement in the photometric precision, will require a small factor larger sample size.
YOLO: Mortality Beliefs and Household Finance Puzzles

Subjective mortality beliefs a ect pre- and post-retirement consumption and savings decisions, as well as portfolio allocation. New survey evidence shows that individuals overestimate their mortality at short horizons and survival rate at long horizons. For example, a 28 year old male with a 99.4% chance of surviving beyond 5 years believes he will do so with 92.8% probability. A 68 year old with a 71.4% probability of living to 78, believes he has a 82.4% chance of living that long. The formation of these beliefs across age cohorts can be attributed to overweighting the most salient causes-of-death, which change over the life-cycle. This bias matters empirically: Survival expectations correlate with heterogeneity in nancial education and investment behavior. Embedded in a run-of-the-mill life-cycle model, these beliefs cause the young to under-save (they have 10% less saved upon retirement) and retirees to not fully draw down their assets (they consume 12% less during retirement). In addition, for reasonable levels of risk- tolerance, the required excess rate of return on equity is in line with historical averages once subjective beliefs are accounted for.
An Adaptive User Profile Based on Memory Model

Understanding the interests and behaviors of Web users serves as the core of many Web usage data mining applications such as personalized search, recommendation, personalization, business decision, advertisement targeting, marketing and customer relationship management. In this paper, an approach of building an adaptive user profile based on memory-model is proposed. The adaptive user profile gives a quantitative measurement of user interests and their changes, which reflects and predicts the interests dynamically and quantitatively, such as the enhancing, decaying of interests and the new interests coming out. It can differentiate long-term and short-term interests as well. It is applied to rank the topic list in which users are interested. In 17160 cases of user log, 70.94% of the nDCG results between user interest ranking list based on memory model and actual ranking list of user are above 90%, significantly higher than reference modeling's.
Design of Compact and Sharp-Rejection Ultra Wideband Bandpass Filters Using Interdigital Stepped-Impedance Resonators

In this paper, a compact ultra-wideband bandpass filter (UWB-BPF) using pseudo-interdigital stepped-impedance resonators (PIDT-SIRs) is designed and implemented on a commercial printed circuit board (PCB) of RT/Duroid 5880 substrate. The first two resonant modes of the SIR are coupled together and they are applied to create a wide passband. The proposed filter at center frequency f 0 of 7.1 GHz has very good measured characteristics including the bandwidth of 3.68-10.46 GHz (3-dB fractional bandwidth of 95%), low insertion loss of -0.5±0.4 dB, sharp rejection due to two transmission zeros in the passband edge created by the inter-stage coupling. Experimental results of the fabricated filter show a good agreement with the predicted results.
Property Rights, Governance, and Economic Development

In this review article we give an intuitive account of why good institutions in general, and secure property rights in particular, matter for economic growth and development. We also discuss implications for good governance, defined as the efficient provision of property rights and other aspects of governance. Finally, we briefly touch on political institutions that might be conducive to good governance and thus economic development.
The major cerebral arteries proximal to the Circle of Willis contribute to cerebrovascular resistance in humans

Cerebral autoregulation ensures constant cerebral blood flow during periods of increased blood pressure by increasing cerebrovascular resistance. However, whether this increase in resistance occurs at the level of major cerebral arteries as well as at the level of smaller pial arterioles is still unknown in humans. Here, we measure cerebral arterial compliance, a measure that is inversely related to cerebrovascular resistance, with our novel non-invasive magnetic resonance imaging-based measurement, which employs short inversion time pulsed arterial spin labelling to map arterial blood volume at different phases of the cardiac cycle. We investigate the differential response of the cerebrovasculature during post exercise ischemia (a stimulus which leads to increased cerebrovascular resistance because of increases in blood pressure and sympathetic outflow). During post exercise ischemia in eight normotensive men (30.4 ± 6.4 years), cerebral arterial compliance decreased in the major cerebral arteries at the level of and below the Circle of Willis, while no changes were measured in arteries above the Circle of Willis. The reduction in arterial compliance manifested as a reduction in the arterial blood volume during systole. This study provides the first evidence that in humans the major cerebral arteries may play an important role in increasing cerebrovascular resistance.
The collective infrastructural work of electricity: exploring feedback in a prepaid university dorm in China

Feedback on resource consumption is often explored as a way to raise awareness and saving resources. This paper reports findings from a user study of a feedback system deployed in a Chinese university dormitory with a prepaid electricity system, a context different from the more common domestic setting in the West explored in prior research. With this work, we move beyond resource conservation and draw attention to an often-neglected aspect of infrastructural work -- the work to ensure the smooth and continuous supply of resources from end users. This paper examines the ways in which people attend to electricity through what we term collective infrastructural work, i.e. people perceive electricity as a marginal concern, and yet invest time to maintain it collectively. We draw out a number of implications for design and evaluation from this work.
Psychological Well-Being, Self-Reported Physical Activity Levels, and Attitudes to Physical Activity in a Sample of New Zealand Adolescent Females

Physical activity (PA) is a key component of healthy development, not only physically but also psychologically. The aim of the present study was to measure PA levels and psychological well-being in adolescent females using a cross-sectional design, and to investigate the relationship between the two. Psychological well-being (self esteem and lack of depression, anxiety, and stress), PA, and established predictors of PA from the Theory of Reasoned Action (Fishbein & Ajzen, 1975; Madden, Ellen, & Ajzen, 1992; health consciousness, significant others, priority, perceived barriers, and attitudes) were measured using 148 adolescent females aged 16 to 18 years. Results show a link between depression and level of PA, and between anxiety and PA. Attitudes towards PA, priority of PA, and perceived barriers to PA were also related to levels of PA. However, there were no significant associations between psychological well-being and attitudes towards PA, even though psychological well-being may influence the actual level of activity. Positive associations between PA and psychological well-being in adolescent females encourage future studies into causal relationships between the two. The most effective strategies for increasing PA in middle to late adolescent females may be targeting perceived barriers to PA rather than attitudes.
Robot-Mediated Interviews - How Effective Is a Humanoid Robot as a Tool for Interviewing Young Children?

Robots have been used in a variety of education, therapy or entertainment contexts. This paper introduces the novel application of using humanoid robots for robot-mediated interviews. An experimental study examines how children’s responses towards the humanoid robot KASPAR in an interview context differ in comparison to their interaction with a human in a similar setting. Twenty-one children aged between 7 and 9 took part in this study. Each child participated in two interviews, one with an adult and one with a humanoid robot. Measures include the behavioural coding of the children’s behaviour during the interviews and questionnaire data. The questions in these interviews focused on a special event that had recently taken place in the school. The results reveal that the children interacted with KASPAR very similar to how they interacted with a human interviewer. The quantitative behaviour analysis reveal that the most notable difference between the interviews with KASPAR and the human were the duration of the interviews, the eye gaze directed towards the different interviewers, and the response time of the interviewers. These results are discussed in light of future work towards developing KASPAR as an ‘interviewer’ for young children in application areas where a robot may have advantages over a human interviewer, e.g. in police, social services, or healthcare applications.
Right Occipital Cortex Activation Correlates with Superior Odor Processing Performance in the Early Blind

Using functional magnetic resonance imaging (fMRI) in ten early blind humans, we found robust occipital activation during two odor-processing tasks (discrimination or categorization of fruit and flower odors), as well as during control auditory-verbal conditions (discrimination or categorization of fruit and flower names). We also found evidence for reorganization and specialization of the ventral part of the occipital cortex, with dissociation according to stimulus modality: the right fusiform gyrus was most activated during olfactory conditions while part of the left ventral lateral occipital complex showed a preference for auditory-verbal processing. Only little occipital activation was found in sighted subjects, but the same right-olfactory/left-auditory-verbal hemispheric lateralization was found overall in their brain. This difference between the groups was mirrored by superior performance of the blind in various odor-processing tasks. Moreover, the level of right fusiform gyrus activation during the olfactory conditions was highly correlated with individual scores in a variety of odor recognition tests, indicating that the additional occipital activation may play a functional role in odor processing.
Incentive Effects of Bonus Payments : Evidence from a Multinational Company

This study uses panel data describing about 6,000 employees in a large multinational company to study the incentive effects of performance related pay. Our company uses two performance related remuneration mechanisms: One is an individual "surprise" bonus payment. The other is a more complex system, where part of the salary is determined by individual performance evaluations. We hypothesize that effort is higher in departments (i) where surprise bonuses are used more frequently, (ii) where performance evaluations are more heterogeneous, (iii) where person-specific performance evaluations are more flexible over time. These hypotheses are tested using days of absence and overtime work as effort indicators. The tests yield that hypothesis (i) is supported in both cases, (ii) is not confirmed and there is evidence to the contrary, and (iii) is supported for overtime, but not for absences. The paper investigates the robustness and heterogeneity of these findings and discusses them in the light of prior empirical studies on the effort effect of performance based pay.
The selection of subcontractors: is price the major factor?

The philosophy of ‘lowest price wins’ in the selection of subcontractors often leads to problems with quality of work and claims for further costs. Since Latham (1994), many models have offered selection methods that take account of a wide range of quality criteria as well as price. A review of existing literature and models enables a list of selection criteria to be drawn up and a survey ascertains which selection criteria are considered most important and whether opinions change when faced with different types of project. The results of the questionnaire are analysed through the use of Simple Relative Indexes, Spearman’s Rank Correlation Coefficient tests and a number of T-tests. It is established that price is no longer considered the only important factor in subcontractor selection, and that health and safety, past performance, and insurance cover are considered equally important and, in some scenarios, more important than price.
Brief Report Results and Discussion

profile that is uniquely associated with a favorable outcome subgroup of acute myeloid leukemia with a distinctive gene expression mutations, define a CEBPA mutations, but not single CEBPA Double Updated information and services can be found at: (2641 articles) Clinical Trials and Observations (1191 articles) Brief Reports (105 articles) Myeloid Neoplasia collections: Blood Articles on similar topics may be found in the following Information about subscriptions and ASH membership may be found online at:. Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome Mutations in CCAAT/enhancer binding protein ␣ (CEBPA) are seen in 5% to 14% of acute myeloid leukemia (AML) and have been associated with a favorable clinical outcome. Most AMLs with CEBPA mutations simultaneously carry 2 mutations (CEBPA double-mut), usually biallelic, whereas single heterozygous mutations (CEBPA single-mut) are less frequently seen. Using denaturing high-performance liquid chromatography and nucleotide sequencing, we identified among a cohort of 598 newly diagnosed AMLs a subset of 41 CEBPA mutant cases (28 CEBPA double-mut and 13 CEBPA single-mut cases). CEBPA double-mut associated with a unique gene expression profile as well as favorable overall and event-free survival, retained in multi-variable analysis that included cytoge-netic risk, FLT3-ITD and NPM1 mutation, white blood cell count, and age. In contrast , CEBPA single-mut AMLs did not express a discriminating signature and could not be distinguished from wild-type cases as regards clinical outcome. These results demonstrate significant underlying heterogeneity within CEBPA mutation-positive AML with prognostic relevance. Introduction Mutations in the transcription factor CCAAT/enhancer binding protein ␣ (CEBPA) are found in 5% to 14% of acute myeloid leukemia (AML). 1-9 CEBPA mutations have been associated with a relatively favorable outcome and have therefore gained interest as a prognostic marker. 4-6,10 Although variable sequence variations have been described, 2 prototypical classes of mutations are most frequent. N-terminal mutations are located between the major translational start codon and a second ATG in the same open reading frame. These mutations introduce a premature stop of translation of the p42 CEBPA protein while preserving translation of a p30 isoform that has been reported to inhibit the function of full-length protein. 2 Mutations in the C-terminal basic leucine zipper (bZIP) region, in contrast, are in-frame and may impair DNA binding and/or homodimerization and heterodimerization. 8 The remaining mutations are mostly found between the N-terminus …
Studies on the nerve pathways involved in the laryngeal reflex (laryngospasm) in the cat.

SUMMARY The receptor sites and nerve pathways involved in the reflex production of laryngospasm have been investigated in the cat. The trigeminal nerves and the internal branch of the superior laryngeal nerves were shown to provide an afferent pathway for the reflex when the nasopharynx and larynx were exposed to ether vapour. Evidence was obtained suggesting that the recurrent laryngeal nerves may form part of the afferent innervation of the trachea involved in this reflex response. The vagus nerves provide an afferent pathway from receptors in the trachea and lungs.
Rbt1 Protein Domains Analysis in Candida albicans Brings Insights into Hyphal Surface Modifications and Rbt1 Potential Role during Adhesion and Biofilm Formation

Cell wall proteins are central to the virulence of Candida albicans. Hwp1, Hwp2 and Rbt1 form a family of hypha-associated cell surface proteins. Hwp1 and Hwp2 have been involved in adhesion and other virulence traits but Rbt1 is still poorly characterized. To assess the role of Rbt1 in the interaction of C. albicans with biotic and abiotic surfaces independently of its morphological state, heterologous expression and promoter swap strategies were applied. The N-terminal domain with features typical of the Flo11 superfamily was found to be essential for adhesiveness to polystyrene through an increase in cell surface hydrophobicity. A 42 amino acid-long domain localized in the central part of the protein was shown to enhance the aggregation function. We demonstrated that a VTTGVVVVT motif within the 42 amino acid domain displayed a high β-aggregation potential and was responsible for cell-to-cell interactions by promoting the aggregation of hyphae. Finally, we showed through constitutive expression that while Rbt1 was directly accessible to antibodies in hyphae, it was not so in yeast. Similar results were obtained for another cell wall protein, namely Iff8, and suggested that modification of the cell wall structure between yeast and hyphae can regulate the extracellular accessibility of cell wall proteins independently of gene regulation.
Clinical Characteristics, Radiological Features and Gene Mutation in 10 Chinese Families with Spinocerebellar Ataxias

Background: Spinocerebellar ataxias (SCAs) are a group of neurodegenerative disorders that primarily cause the degeneration in the cerebellum, spinal cord, and brainstem. We study the clinical characteristics, radiological features and gene mutation in Chinese families with SCAs. Methods: In this study, we investigated 10 SCAs Chinese families with SCA1, SCA3/Machado–Joseph disease (MJD), SCA7, SCA8. There were 27 people who were genetically diagnosed as SCA, of which 21 people showed clinical symptoms, and 6 people had no clinical phenotype that we called them presymptomatic patients. In addition, 3 people with cerebellar ataxia and cataracts were diagnosed according to the Harding diagnostic criteria but failed to be recognized as SCAs on genetic testing. Clinical characteristic analyses of each type of SCAs and radiological examinations were performed. Results: We found that SCA3/MJD was the most common subtype in Han population in China, and the ratio of the pontine tegmentum and the posterior fossa area was negatively correlated with the number of cytosine-adenine-guanine (CAG) repeats; the disease duration was positively correlated with the International Cooperative Ataxia Rating Scale score; and the CAG repeats number of abnormal alleles was negatively correlated with the age of onset. Conclusions: Collectively our study is a systematic research on SCAs in China, which may help for the clinical diagnosis and prenatal screening of this disease, and it may also aid toward better understanding of this disease.
Fully Redundant Decimal Arithmetic

Hardware implementation of all the basic radix-10 arithmetic operations is evolving as a new trend in the design and implementation of general purpose digital processors. Redundant representation of partial products and remainders is common in the multiplication and division hardware algorithms, respectively. Carry-free implementation of the more frequent add/subtract operations, with the byproduct of enhancing the speed of multiplication and division, is possible with redundant number representation. However, conversion of redundant results to conventional representations entails slow carry propagation that can be avoided if the results are kept in redundant format for later use as operands of other arithmetic operations. Given that redundant decimal representations, contrary to redundant binary, do not necessarily require extra storage, we are motivated to develop a framework for fully redundant decimal arithmetic, where all operands and results belong to the same redundant decimal number system and can be stored and later used as operands of further decimal operations. In this paper, we present a new faster decimal signed digit add/sub unit and show how it can be efficiently used in the design of decimal multipliers and dividers, where all operands and results are represented with the same redundant digit set [–7, 7].