Miracle-dz/UniFAR-FTUs huggingface dataset:
Development of a performance assessment tool for rock climbers

Abstract Rock climbing is a popular adventure sport for which there is a growing body of scientific knowledge. There is, however, a lack of sport-specific assessment tools to monitor performance. The aim of this study was to examine the potential of the rock-over climbing test (ROCT) as a measure of climbing performance. The ROCT was conducted on a climbaflex board and involved the climber making a rock-over move for which the height gained from lower to upper handhold was measured. Results indicated there was a significant relationship between scaled (to the height of the climber) ROCT scores and climbing ability (r=0.67, P<0.0005). Regression modelling revealed that the ROCT explained 45% of the variance in scores between climbers. The ROCT differentiated between climber ability levels. Mean ROCT scores for novice, intermediate, advanced, and elite climbers were 59.5%, 71%, 82%, and 90% of participant height respectively. Results of analysis of variance revealed that these differences were significant (F 3,42=13.38, P<0.0005). Limits of agreement and intra-class correlation indicated that the ROCT is a reliable performance measure. Our findings suggest that the ROCT is a useful measure of climbing performance.
Intrapulmonary lesions: percutaneous automated biopsy with a detachable, 18-gauge, coaxial cutting needle.

PURPOSE To evaluate a lung biopsy technique in which a detachable, 18-gauge, coaxial guide around a central notched stylet is used as a cutting needle. MATERIALS AND METHODS The records of 89 consecutive patients (41 women, 48 men; aged 21-86 years) who underwent coaxial percutaneous core biopsy of 91 lung lesions that required needle passage through normal lung tissue (mean lesion size, 33.6 mm; range, 9-80 mm) were studied. Detachable, 18-gauge, coaxial automated cutting needles were used. RESULTS The mean number of needle passes was 2.5 (range, 1-4). All biopsies yielded sufficient tissue for histopathologic (n = 91) and, if necessary, bacteriologic (n = 12) evaluation (mean core length, 5 mm; range, 1-15 mm). Eighty-nine lesions had definitive diagnoses. Seventy-five lesions were proved to be malignant; seventy (93%) could be accurately diagnosed with coaxial percutaneous core biopsy samples. Fourteen lesions were proved to be benign; 10 (71%) were specifically diagnosed with biopsy samples. Among the 91 biopsies, the overall diagnostic accuracy was 88% (80 of 91 lesions). A pneumothorax occurred in 31 cases (34%), three (3%) of which necessitated placement of a chest tube. Postbiopsy hemoptysis occurred and resolved spontaneously in nine cases (10%). CONCLUSION This technique provides a core biopsy specimen without the need for an on-site cytopathologist during the procedure. It has a high diagnostic accuracy and an acceptable rate of complications.
The effects of multi-oil fat emulsion on older patients with gastric cancer

Objective: To explore the effect of Multi-oil Fat Emulsion (SMOF) in perioperative parenteral nutritional support on older patients with gastric cancer. Methods: 120 patients with gastric cancer were evenly and randomly assigned to Control, Intralipid and SMOF group. Nutritional status, immune function and liver function in three groups were compared among 0 dpo (day post operation), 3 dpo and 7 dpo. Complications, length of stay and hospital costs were analyzed, as well. Results: Significant differences were observed in nutritional status, immune function and liver function among three groups during perioperative period. After surgery, ALB, PAB, TF in Intralipid and SMOF group were significantly higher than in that Control group (P<0.01). CD3, CD4, CD4/CD8, IgA, IgG, IgM levels after surgery in SMOF group were significantly higher than in that Control and Intralipid group (P<0.05). CRP and IL-6 and TBIL levels of 7 dpo in SMOF group were significantly lower than other two groups, especially Intralipid group (P<0.01). SMOF group had the lowest complication incidence (P<0.05). Conclusion: SMOF in perioperative parenteral nutritional support contributes to older gastric cancer patients with significantly improved immune function, reduced complications and without increasing hospital costs. A Cohort study with greater patient numbers is needed.
Nonuniversal Conductance Quantization in Quantum Wires.

We have measured the transport properties of high-quality quantum wires fabricated in GaAs-AlGaAs by using cleaved edge overgrowth. The low temperature conductance is quantized as the electron density in the wire is varied. While the values of the conductance plateaus are reproducible, they deviate from multiples of the universal value of 2e2yh by as much as 25%. As the temperature or dc bias increases the conductance steps approach the universal value. Several aspects of the data can be explained qualitatively using Luttinger liquid theory although there remain major inconsistencies with such an interpretation. [S0031-9007(96)01675-4]
Constraints on the models for structure formation from the abundance of damped Lyman alpha systems

Models for structure formation attempt to predict the power spectrum of density perturbations in the present universe from the initial power spectrum and the nature of dark matter. Observational constraints on the power spectrum at different scales in the present epoch can, therefore, be used to eliminate (or choose between) different theoretical models. Such a comparison is fairly easy at large scales (at which linear theory is valid), and one can use observations like the MBR anisotropy, large scale steaming motions etc to constrain the models. But to discriminate between the models effectivley, it is necessay to constrain the power spectrum at small scales. The most reliable constraints on the power spectra at small scales come from the predicted abundance of bound systems which can be estimated reasonably accurately using Press-Schecter (or similar) methods$^1$. In the past, this method has been used in conjunction with the quasar abundance$^{2-4}$ and cluster abundance$^{5-7}$. We show here that the abundance of damped lyman alpha systems (DLAS, hereafter), provides a far stronger constraint on the models for structure formation. Models with a mixture of hot and cold dark matter $^{8-11}$ (which are consistent with large scale observations) are strongly ruled out by the DLAS constraints while models with cosmological constant $^{12}$ are marginally inconsistent. It is also possible to combine the constraints from the abundance of clusters, DLAS and QSO's to obtain model-independent bounds on the power spectrum at the nonlinear scales. These bounds are to be respected by any viable model for structure formation.
Maternal and fetal outcomes if gestational impaired glucose tolerance is not treated.

OBJECTIVE To evaluate whether there is increased maternal or neonatal morbidity in connection with impaired glucose tolerance (IGT) during pregnancy when the condition is not treated. RESEARCH DESIGN AND METHODS During the study period of 1997-2001, in a defined geographical area in Sweden, the diagnostic criteria for gestational diabetes mellitus (GDM) were limited to the criteria for diabetes. Prospectively, 213 women who were identified with IGT during pregnancy were undiagnosed and untreated. Data on maternal and fetal outcome was collected from records. For each case subject, four control subjects were taken from the same delivery department. RESULTS The proportion of women who underwent cesarean section was significantly higher in the case subjects than in the control subjects and was independently associated with IGT. The adjusted odds ratio (OR) was 1.9 (95% CI 1.2-2.9). The proportion of infants who were large for gestational age (LGA), defined as birth weight >2 SDs greater than the mean for gestation and sex, was independently significantly associated with untreated IGT during pregnancy (OR 7.3, 95% CI 4.1-12.7). Admission to a neonatal intensive care unit (NICU) for 2 days or longer was more common (adjusted OR 2.0, 95% CI 1.1-3.8). However, 71.3% of the children in the IGT group and 87.3% of the control subjects had no neonatal complications. CONCLUSIONS There is increased independent association between cesarean section rate, prematurity, LGA, and macrosomic infants born to mothers with untreated IGT. Most of the children were healthy, but there is still increased morbidity. Therefore, to evaluate the effects of treatment, there is a need for a randomized study.
Single-Shared Network with Prior-Inspired Loss for Parameter-Efficient Multi-Modal Imaging Skin Lesion Classification

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel fusion schemes. Firstly, unlike current methods that usually employ two individual models for for clinical and dermoscopy modalities, we verified that multimodal feature can be learned by sharing the parameters of encoder while leaving the individual modal-specific classifiers. Secondly, the shared cross-attention module can replace the individual one to efficiently interact between two modalities at multiple layers. Thirdly, different from current methods that equally optimize dermoscopy and clinical branches, inspired by prior knowledge that dermoscopy images play a more significant role than clinical images, we propose a novel biased loss. This loss guides the single-shared network to prioritize dermoscopy information over clinical information, implicitly learning a better joint feature representation for the modal-specific task. Extensive experiments on a well-recognized Seven-Point Checklist (SPC) dataset and a collected dataset demonstrate the effectiveness of our method on both CNN and Transformer structures. Furthermore, our method exhibits superiority in both accuracy and model parameters compared to currently advanced methods.
Politics, power & the podium: coaching for Paralympic performance

This paper considers the cultural politics of working with elite athletes with a disability. The focus of the paper is a coach who has dedicated his career to performance athletes with a disability – Robert Ellchuk – and draws on the coach’s personal experiences and ethnographic work with four different coach-Paralympic athlete dyads. These data are (re)presented in the form of a reflexive conversation supplemented with post-conversation reflections. Important questions are raised about the structure of ‘coach education’, the role of a coach, hierarchies within disabled sport, the impact of commodification on the disabled body and the (perceived) barriers to physical activity for disabled participants. The article concludes with an invitation to readers to make their own meaning of this polysemic narrative, especially at a time when specific representations of ‘acceptable’ disabled bodies will be circulated in, and through, the London 2012 Olympic and Paralympic Games.
Recreating Riser Slugging Flow Based on an Economic Lab-Sized Setup

Abstract As a kind of periodic phenomenon, the slugging flow in the offshore oil & gas production addresses a lot of attentions, due to its limitation of production rate, periodic overload processing facilities, and even direct cause of emergent shutdown. This work studies the emulation of the riser slugging flow in the offshore oil & gas production, by constructing an economical lab-sized setup in the university campus. Firstly, the construction and used components for the lab setup are illustrated; then, the constructed setup is validated by checking the consistency with some existing typical riser slug model, besides extensive experimental tests. The theoretical analysis and experimental results show that this simple setup can recreate the key features of slugging flow phenomenon with reasonable preciseness, and it serves as a good platform for further slug control study.
Regulatory T Cells in Central Nervous System Injury: A Double-Edged Sword

Previous research investigating the roles of T effector (Teff) and T regulatory (Treg) cells after injury to the CNS has yielded contradictory conclusions, with both protective and destructive functions being ascribed to each of these T cell subpopulations. In this work, we study this dichotomy by examining how regulation of the immune system affects the response to CNS trauma. We show that, in response to CNS injury, Teff and Treg subsets in the CNS-draining deep cervical lymph nodes are activated, and surgical resection of these lymph nodes results in impaired neuronal survival. Depletion of Treg, not surprisingly, induces a robust Teff response in the draining lymph nodes and is associated with impaired neuronal survival. Interestingly, however, injection of exogenous Treg cells, which limits the spontaneous beneficial immune response after CNS injury, also impairs neuronal survival. We found that no Treg accumulate at the site of CNS injury, and that changes in Treg numbers do not alter the amount of infiltration by other immune cells into the site of injury. The phenotype of macrophages at the site, however, is affected: both addition and removal of Treg negatively impact the numbers of macrophages with alternatively activated (tissue-building) phenotype. Our data demonstrate that neuronal survival after CNS injury is impaired when Treg cells are either removed or added. With this exacerbation of neurodegeneration seen with both addition and depletion of Treg, we recommend exercising extreme caution when considering the therapeutic targeting of Treg cells after CNS injury, and possibly in chronic neurodegenerative conditions.
On the potential of quantum walks for modeling financial return distributions

Accurate modeling of the temporal evolution of asset prices is crucial for understanding financial markets. We explore the potential of discrete-time quantum walks to model the evolution of asset prices. Return distributions obtained from a model based on the quantum walk algorithm are compared with those obtained from classical methodologies. We focus on specific limitations of the classical models, and illustrate that the quantum walk model possesses great flexibility in overcoming these. This includes the potential to generate asymmetric return distributions with complex market tendencies and higher probabilities for extreme events than in some of the classical models. Furthermore, the temporal evolution in the quantum walk possesses the potential to provide asset price dynamics.
The Study of New Religious Movements and the Radicalization of Home-Grown Terrorists: Opening a Dialogue

This article examines: (1) the obvious reasons for, and curious absence of, a dialogue between scholars studying new religious movements (NRMs), particularly those responsible for acts of mass violence, and those studying processes of radicalization in home-grown terrorist groups; (2) the substantial parallels between established understandings of who joins NRMs, how, and why and recent findings about who joins terrorist groups in a Western context, how, and why; and (3) the ways in which explanations of the causes of violent behaviour in NRMs are pertinent to securing a more systematic and complete grasp of the process of radicalization in terrorist cells. The latter discussion focuses on the role of apocalyptic belief systems and charismatic forms of authority, highlighting the behavioural consequences of this dangerous combination and their possible strategic significance. Recommendations are made for further research, integrating insights from the two fields of study.
Benchmarking Complications Associated with Esophagectomy

Objective: Utilizing a standardized dataset with specific definitions to prospectively collect international data to provide a benchmark for complications and outcomes associated with esophagectomy. Summary of Background Data: Outcome reporting in oncologic surgery has suffered from the lack of a standardized system for reporting operative results particularly complications. This is particularly the case for esophagectomy affecting the accuracy and relevance of international outcome assessments, clinical trial results, and quality improvement projects. Methods: The Esophageal Complications Consensus Group (ECCG) involving 24 high-volume esophageal surgical centers in 14 countries developed a standardized platform for recording complications and quality measures associated with esophagectomy. Using a secure online database (ESODATA.org), ECCG centers prospectively recorded data on all resections according to the ECCG platform from these centers over a 2-year period. Results: Between January 2015 and December 2016, 2704 resections were entered into the database. All demographic and follow-up data fields were 100% complete. The majority of operations were for cancer (95.6%) and typically located in the distal esophagus (56.2%). Some 1192 patients received neoadjuvant chemoradiation (46.1%) and 763 neoadjuvant chemotherapy (29.5%). Surgical approach involved open procedures in 52.1% and minimally invasive operations in 47.9%. Chest anastomoses were done most commonly (60.7%) and R0 resections were accomplished in 93.4% of patients. The overall incidence of complications was 59% with the most common individual complications being pneumonia (14.6%) and atrial dysrhythmia (14.5%). Anastomotic leak, conduit necrosis, chyle leaks, recurrent nerve injury occurred in 11.4%, 1.3%, 4.7%, and 4.2% of cases, respectively. Clavien-Dindo complications ≥ IIIb occurred in 17.2% of patients. Readmissions occurred in 11.2% of cases and 30- and 90-day mortality was 2.4% and 4.5%, respectively. Conclusion: Standardized methods provide contemporary international benchmarks for reporting outcomes after esophagectomy.
The Door That Leads Into Madness: Eastern European Poets and Mental Illness

The image of the poet as a doomed, lonely, depressedfigure is a persistent archetype in our culture. Poetsthemselvesmaynotappreciatesuchassociations—for-mer U. S. Poet Laureate Billy Collins, for example, ar-gues “the assumed association of poets with mentaldisorders and depression is a romantic holdover”(quoted in Levin, 2003), and writer CarolMuske-Dukes has said, “The way poets write has noth-ing to do with their health” (quoted in Murillo, 2004). Yet a multitude of research studies have demonstratedsome type of association between mental illness andcreativity, even if there is still much debate over the ex-tent and nature of this relationship (e.g., Jamison,1993; Rothenberg, 1990; Waddell, 1998). Some studies have further specified a link betweencreative writing and mental illness. Andreasen (1987)explored this relationship by comparing writers with acontrol group and found that not only were writersmore likely to suffer from affective disorders (specifi-cally bipolar disorder) but so were the writers’first-de-gree relatives. Ludwig (1994) studied 59 female writ-ers and 59 matched controls. He found that the writerswere more likely to have mental illness, includingmood disorders and general anxieties.Ludwig (1995) also conducted a separatelarge-scale investigation of over 1,000 eminent indi-viduals who were the subjects of major biographieswritten between 1960 and 1990. He found a higher in-cidence of mental illness among those in artistic pro-fessions (e.g., writing, art, and theater) than innonartisticprofessions(e.g.,business,politics,andsci-ence). Jamison (1989) studied British artists and writ-ers and found that a significantly higher percentage ofthem suffered from some form of mental illness thanwould be expected from the rates found in the generalpopulation, with affective disorders again especiallyprevalent. Post (1994, 1996) studied and diagnosedeminent men and found higher rates of personality dis-orders and depression (1994) and mental pathology(1996) in writers.Other research has focused on what
The assessment of fitness to stand trial for defendants with an intellectual disability: A proposed assessment procedure involving mental health professionals and lawyers

Guidelines for mental health professionals regarding an assessment of fitness to stand trial procedure that is functional, context‐dependent and pragmatic (Grisso, 1988) are clearly required; no published tool exists in Australia. This article addresses Victorian legal criteria as outlined by the Crimes (Mental Impairment and Unfitness to be Tried) Act 1997 based upon the Presser criteria. It is argued that the procedure should include the lawyer's predictions regarding the complexity of the forthcoming trial and the ability of the defendant to communicate, together with the mental health professional's assessment of the capacity of the defendant to make decisions. Current difficulties in assessing fitness to stand trial will be presented and an assessment procedure to overcome them is proposed.
Identification of Immunoreactive Leishmania infantum Protein Antigens to Asymptomatic Dog Sera through Combined Immunoproteomics and Bioinformatics Analysis

Leishmania infantum is the etiologic agent of zoonotic visceral leishmaniasis (VL) in countries in the Mediterranean basin, where dogs are the domestic reservoirs and represent important elements in the transmission of the disease. Since the major focal areas of human VL exhibit a high prevalence of seropositive dogs, the control of canine VL could reduce the infection rate in humans. Efforts toward this have focused on the improvement of diagnostic tools, as well as on vaccine development. The identification of parasite antigens including suitable major histocompatibility complex (MHC) class I- and/or II-restricted epitopes is very important since disease protection is characterized by strong and long-lasting CD8+ T and CD4+ Th1 cell-dominated immunity. In the present study, total protein extract from late-log phase L. infantum promastigotes was analyzed by two-dimensional western blots and probed with sera from asymptomatic and symptomatic dogs. A total of 42 protein spots were found to differentially react with IgG from asymptomatic dogs, while 17 of these identified by Coommasie stain were extracted and analyzed. Of these, 21 proteins were identified by mass spectrometry; they were mainly involved in metabolism and stress responses. An in silico analysis predicted that the chaperonin HSP60, dihydrolipoamide dehydrogenase, enolase, cyclophilin 2, cyclophilin 40, and one hypothetical protein contain promiscuous MHCI and/or MHCII epitopes. Our results suggest that the combination of immunoproteomics and bioinformatics analyses is a promising method for the identification of novel candidate antigens for vaccine development or with potential use in the development of sensitive diagnostic tests.
Cybervision: Virtual peer group counselling supervision — Hindrance or help?

This study explored the use of text-based computer-mediated communication in counsellor supervision. ‘Cybervision’ is an innovative collaboration between counsellors and computer technology. The study reports on the use of clinical case presentation by e-mail and the discussion of cases in text-based chat rooms. The inquiry, conducted from a qualitative research perspective, seeks to explore the potential effectiveness of Cybervision along with its advantages and disadvantages. Prior to each supervision session, the supervisee presented case concerns by e-mail and later received 60 minutes supervision from the remaining three group members adopting the role of supervisor. As a form of co-operative inquiry, the personal experience of research participants was investigated and reported, highlighting key themes and issues relating to the absence of face-to-face contact. In all cases, participants reported that Cybervision effectively influenced and informed the clinical practice of the counsellor. Participan.