Miracle-dz/UniFAR-FTUs huggingface dataset:
Soy-Based Infant Formula Feeding and Ultrasound-Detected Uterine Fibroids among Young African-American Women with No Prior Clinical Diagnosis of Fibroids

Background: Early-life soy phytoestrogen exposure has been shown in Eker rats to increase uterine fibroid incidence in adulthood. Two large epidemiologic cohorts have provided some support for increased fibroid risk with infant soy formula feeding in women, but both cohorts relied on self-report of clinically diagnosed fibroids. Objective: We evaluated the relationship between infant soy formula feeding and ultrasound-detected fibroids. Methods: The Study of Environment, Lifestyle & Fibroids (SELF) is an ongoing cohort study of 1,696 African-American women ages 23–34 years with baseline ultrasound screening to detect and measure fibroids ≥ 0.5 cm in diameter. Questionnaire data on soy formula feeding during infancy was ascertained for 1,553 participants (89% based on mother’s report), of whom 345 were found to have fibroids. We estimated the association between soy formula feeding and fibroid prevalence and tumor number using log-binomial regression. Among those with fibroids, we compared fibroid size between soy formula-exposed and unexposed women using multivariable linear regression. Results: We did not observe an association between soy formula feeding and fibroid prevalence [adjusted prevalence ratio (aPR) 0.9, 95% CI: 0.7, 1.3]. Nor were exposed women with fibroids more likely to have ≥ 2 tumors than unexposed women with fibroids (aPR 1.0, 95% CI: 0.7, 1.6). However, exposed women with fibroids had significantly larger fibroids than unexposed women with fibroids. On average, soy formula feeding was associated with a 32% increase in the diameter of the largest fibroid (95% CI: 6%, 65%) and a 127% increase in total tumor volume (95% CI: 12%, 358%). Conclusions: Our observation that women fed soy formula as infants have larger fibroids than unexposed women provides further support for persistent effects of early life phytoestrogen exposure on the uterus. Citation: Upson K, Harmon QE, Baird DD. 2016. Soy-based infant formula feeding and ultrasound-detected uterine fibroids among young African-American women with no prior clinical diagnosis of fibroids. Environ Health Perspect 124:769–775; http://dx.doi. org/10.1289/ehp.1510082
How the “Truth” Self Relates to Altruism: When Your Problem is Mine

It has been argued that the phenomenal self sees the world from an “egocentric” perspective. But then how do we explain why people give up their own time and resources on behalf of others? We propose that one answer to this question can be found in people's subjective experience of motivation to establishing what's real—the phenomenal “truth” self. In seeking the truth, people want to establish not only what is correct and real but also what is right, including morally right. We propose that the experience of being effective in figuring things out and solving problems relates positively to solving others’ problems as well; that is, altruistic behaviors that help others. In support of this proposal, we touch upon ethical theories in philosophy and religion that have drawn the connection between seeking the truth and being moral, and we review research in comparative and social psychology suggesting how experiencing a “truth” self would support helping others. We also report two empirical studies demonstrat.
Carbapenemase Genes among Multidrug Resistant Gram Negative Clinical Isolates from a Tertiary Hospital in Mwanza, Tanzania

The burden of antimicrobial resistance (AMR) is rapidly growing across antibiotic classes, with increased detection of isolates resistant to carbapenems. Data on the prevalence of carbapenem resistance in developing countries is limited; therefore, in this study, we determined the prevalence of carbapenemase genes among multidrug resistant gram negative bacteria (MDR-GNB) isolated from clinical specimens in a tertiary hospital in Mwanza, Tanzania. A total of 227 MDR-GNB isolates were analyzed for carbapenem resistance genes. For each isolate, five different PCR assays were performed, allowing for the detection of the major carbapenemase genes, including those encoding the VIM-, IMP-, and NDM-type metallo-beta-lactamases, the class A KPC-type carbapenemases, and the class D OXA-48 enzyme. Of 227 isolates, 80 (35%) were positive for one or more carbapenemase gene. IMP-types were the most predominant gene followed by VIM, in 49 (21.59%) and 28 (12%) isolates, respectively. Carbapenemase genes were most detected in K. pneumoniae 24 (11%), followed by P. aeruginosa 23 (10%), and E. coli with 19 isolates (8%). We have demonstrated for the first time a high prevalence of MDR-GNB clinical isolates having carbapenem resistance genes in Tanzania. We recommend routine testing for carbapenem resistance among the MDR-GNB particularly in systemic infections.
Neurocognitive interventions for children and adolescents surviving cancer.

BACKGROUND It is well recognized that many cures for childhood leukemia and brain tumors entail some relatively permanent neurocognitive and psychological costs to the patient and family. As cure rates have improved over the past three decades, increasing efforts have been directed toward reducing treatment-related late effects. OBJECTIVE The particular focus of this review will be on interventions for the neuropsychological late effects associated with the treatment of acute lymphoblastic leukemia (ALL) and malignant brain tumors. SUMMARY We will first briefly review current approaches to the medical treatment of ALL and brain tumors to provide an appreciation of potential sources of brain injury. We will then summarize the existing literature on types of neuropsychological deficits found among survivors, with special attention to variables that place some children at greater risk. Then, there will be a discussion of approaches to intervention for these deficits-specifically, cognitive remediation, pharmacology, and ecological alterations in the classroom. Finally, we will present directions for future research in the field.
Estimating Affine Multifactor Term Structure Models Using Closed-Form Likelihood Expansions

We develop and implement a technique for closed-form maximum likelihood estimation (MLE) of multifactor affine yield models. We derive closed-form approximations to likelihoods for nine Dai and Singleton (2000) affine models. Simulations show our technique very accurately approximates true (but infeasible) MLE. Using US Treasury data, we estimate nine affine yield models with different market price of risk specifications. MLE allows non-nested model comparison using likelihood ratio tests; the preferred model depends on the market price of risk. Estimation with simulated and real data suggests our technique is much closer to true MLE than Euler and quasi-maximum likelihood (QML) methods.
Physiotherapy Practice Patterns for Management of Patients Undergoing Thoracic Surgeries in India: A Survey

Aim. The aim of the current study is to determine the practice patterns of physiotherapists for patients undergoing thoracic surgeries in India. Materials and Methodology. A cross-sectional survey was conducted across India in which 600 questionnaires were sent in emails to physiotherapists. The questionnaire addressed assessment and treatment techniques of thoracic surgery. Results. A total of 234 completed questionnaires were returned with a response rate of 39%, with the majority of responses received from Telangana, Karnataka, and Andhra Pradesh. More than 90% of the responders practiced physical examination, chest expansion, chest X-ray, ABG analysis, pulmonary function test, and SpO2 (oxygen saturation) as the assessment measures in both the pre- and the postoperative phase. Breathing exercises, incentive spirometry, thoracic expansion exercises, coughing and huffing, positioning, and modified postural drainage are found to be commonly used physiotherapy interventions, both pre- and postoperatively, with a response rate of more than 90%. A response rate of more than 84.6% indicated that patients are made to dangle their lower limbs over the edge of the bed on the 1st postoperative day. Mobilization, such as walking up to a chair, sit to stand exercises, and perambulation within the patient's room, was started on the 2nd postoperative day, as stated by more than 65% of the physiotherapists. Staircase climbing was started on the 5th postoperative day. The most commonly used functional evaluation prior to discharge was 6-minute walk test. This was, in fact, practiced by 77.4% of the physiotherapists in their clinical settings. Conclusion. The most predominantly employed assessment measures included were physical examination, chest expansion, ABG analysis, pulmonary function test, chest X-ray, SpO2 (oxygen saturation), peripheral muscle strength, and cardiopulmonary exercise. The physiotherapy interventions most commonly used were breathing exercises, thoracic expansion exercises, incentive spirometry, and coughing and huffing techniques, in both the pre- and the postoperative phase.
Proteus: computing disjunctive loop summary via path dependency analysis

Loops are challenging structures for program analysis, especially when loops contain multiple paths with complex interleaving executions among these paths. In this paper, we first propose a classification of multi-path loops to understand the complexity of the loop execution, which is based on the variable updates on the loop conditions and the execution order of the loop paths. Secondly, we propose a loop analysis framework, named Proteus, which takes a loop program and a set of variables of interest as inputs and summarizes path-sensitive loop effects on the variables. The key contribution is to use a path dependency automaton (PDA) to capture the execution dependency between the paths. A DFS-based algorithm is proposed to traverse the PDA to summarize the effect for all feasible executions in the loop. The experimental results show that Proteus is effective in three applications: Proteus can 1) compute a more precise bound than the existing loop bound analysis techniques; 2) significantly outperform state-of-the-art tools for loop verification; and 3) generate test cases for deep loops within one second, while KLEE and Pex either need much more time or fail.
Functional properties of wheat and sweet potato flour blends.

In this study the functional properties of wheat and sweet potato tuber (Ipomea batatas) flou r blends were investigated. The sweet potato tubers were brought from local farm in Offa Kwara State. The tubers were thoroughly sorted, washed, peeled, sliced, blanched, soaked, drained, sundries and milled into flour. Wheat flour used was purchased at Orisumbare market in Osogbo Osun State. The wheat and sweet potato flour were blended using the following ratios (WF:SPF:100:0, 90:10, 85:15, 80:20, 75:25, 0:100). These samples were thereafter subjected to functional properties analysis. The results revealed that as more and more sweet potato flour was added to wheat flour, there was significant effect on the functional properties.
The Reverberations of a Graduate Study Abroad Course in India

Faculty in a transdisciplinary graduate program in holistic health studies, which is grounded in transformational learning led a study abroad course in India. The focus of the course is on perspectives of health and healing in India, including an understanding of Yoga, meditation, Ayurvedic medicine, and Tibetan medicine. The purpose of this phenomenological research is to describe the experiences of 13 holistic health studies graduate students who participated in this graduate study abroad course. Qualitative data were collected from students at the time of application to the course, 1 month after returning from India, and 1 year later. In addition, student applications, posttrip reflection papers, photographs, notes taken by faculty at a 1-year reunion, and results of an electronic survey were used as data. Results suggest that students experienced “mind, body and spirit” transformations with reverberations on personal, community, and global levels.
Muscle Plasticity and β2-Adrenergic Receptors: Adaptive Responses of β2-Adrenergic Receptor Expression to Muscle Hypertrophy and Atrophy

We discuss the functional roles of β2-adrenergic receptors in skeletal muscle hypertrophy and atrophy as well as the adaptive responses of β2-adrenergic receptor expression to anabolic and catabolic conditions. β2-Adrenergic receptor stimulation using anabolic drugs increases muscle mass by promoting muscle protein synthesis and/or attenuating protein degradation. These effects are prevented by the downregulation of the receptor. Endurance training improves oxidative performance partly by increasing β2-adrenergic receptor density in exercise-recruited slow-twitch muscles. However, excessive stimulation of β2-adrenergic receptors negates their beneficial effects. Although the preventive effects of β2-adrenergic receptor stimulation on atrophy induced by muscle disuse and catabolic hormones or drugs are observed, these catabolic conditions decrease β2-adrenergic receptor expression in slow-twitch muscles. These findings present evidence against the use of β2-adrenergic agonists in therapy for muscle wasting and weakness. Thus, β2-adrenergic receptors in the skeletal muscles play an important physiological role in the regulation of protein and energy balance.
I Don't Like the Cut of your Jib: Perceived Facial Masculinity as a Cue to Criminality

Previous research has established that the appearance of criminal suspects and defendants can affect subsequent legal decisions. Specifically, researchers have proposed that (1) masculine suspects are believed to commit more stereotypically male crimes (e.g., burglary), (2) masculine suspects are believed to commit more violent crimes (e.g., assault), and (3) masculinity is a general cue for committing crime. The current study sought to test these competing hypotheses regarding masculine appearance and perceived criminality. Across three studies, participants read a brief crime scenario and were asked to select out of a lineup the suspect they believed had committed the crime. Suspect masculinity and type of crime were manipulated to determine whether the degree of masculinity influenced whether participants believed they had committed the crime. Results showed that participants consistently associated masculinity with committing violent crime and showed some evidence for the general criminality hypothesis on secondary measures. These findings have important implications regarding law enforcement, eyewitness and juror bias, and legal decisions.
Immunocytochemical analysis of the mouse retina

Transgenic mice provide a new approach for studying the structure and function of the mammalian retina. In the past, the cellular organization of the mammalian retina was investigated preferentially in primates, cats, and rats but rarely in mice. In the current study, the authors applied 42 different immunocytochemical markers to sections of the mouse retina and studied their cellular and synaptic localization by using confocal microscopy. The markers applied were from three major groups: 1) antibodies against calcium‐binding proteins, such as calbindin, parvalbumin, recoverin, or caldendrin; 2) antibodies that recognize specific transmitter systems, such as glycine, γ‐aminobutyric acid, or acetylcholine; and 3) antibodies that recognize transmitter receptors and show their aggregation at specific synapses. Only a few markers labeled only one cell type: Most antibodies recognized specific groups of neurons. These were analyzed in more detail in double‐labeling experiments with different combinations of the antibodies. In light of their results, the authors offer a list of immunocytochemical markers that can be used to detect possible changes in the retinal organization of mutant mice. J. Comp. Neurol. 424:1–23, 2000. © 2000 Wiley‐Liss, Inc.
Video-Aware Scheduling and Caching in the Radio Access Network

In this paper, we introduce distributed caching of videos at the base stations of the Radio Access Network (RAN) to significantly improve the video capacity and user experience of mobile networks. To ensure effectiveness of the massively distributed but relatively small-sized RAN caches, unlike Internet content delivery networks (CDNs) that can store millions of videos in a relatively few large-sized caches, we propose RAN-aware reactive and proactive caching policies that utilize User Preference Profiles (UPPs) of active users in a cell. Furthermore, we propose video-aware backhaul and wireless channel scheduling techniques that, in conjunction with edge caching, ensure maximizing the number of concurrent video sessions that can be supported by the end-to-end network while satisfying their initial delay requirements and minimize stalling. To evaluate our proposed techniques, we developed a statistical simulation framework using MATLAB and performed extensive simulations under various cache sizes, video popularity and UPP distributions, user dynamics, and wireless channel conditions. Our simulation results show that RAN caches using UPP-based caching policies, together with video-aware backhaul scheduling, can improve capacity by 300% compared to having no RAN caches, and by more than 50% compared to RAN caches using conventional caching policies. The results also demonstrate that using UPP-based RAN caches can significantly improve the probability that video requests experience low initial delays. In networks where the wireless channel bandwidth may be constrained, application of our video-aware wireless channel scheduler results in significantly (up to 250%) higher video capacity with very low stalling probability.
Valores normativos de una escala de autoeficacia académica en estudiantes universitarios de Lima

This paper synthesize the obtention of normative data of Academic Situations Specific Perceived Self-efficacy Scale (ASSPSE) from Lima. Were evaluated 883 college students (75.5% women) with aged between 16 and 56 years (M = 22.16). The confirmatory factor analysis performed shows an unidimensional structure, and reliability coefficients (α, ω y H) have high magnitude. The ASSPSE scores not has normal distribution, and the normative data were elaborated with percentiles. The results are discussed and practical guidelines are given for the use of the norms.
Neuropsychological profiles of adolescents with ADHD: effects of reading difficulties and gender.

BACKGROUND Executive function, particularly behavioral inhibition, has been implicated as a core deficit specific to Attention-Deficit/Hyperactivity Disorder (ADHD) whereas rapid naming has been implicated as a core deficit specific to reading disabilities (RD). Females may be less impaired in executive function although adolescent females with ADHD have yet to be studied. METHOD Neuropsychological profiles of four adolescent groups aged 13-16 with equal female representation were investigated: 35 ADHD, 12 RD, 24 ADHD+RD, and 37 normal controls. A semi-structured interview (K-SADS-PL), the Conners Rating Scales and the Ontario Child Health Study Scales were used to diagnose ADHD. RD was defined as a standard score below 90 on at least one of the following: Reading or Spelling of the WRAT3 or Word Attack or Word Identification of the WRMT-R. The WISC-III, Rapid Automatized Naming, Stroop and Stop tasks were used as measures of cognitive and executive function. RESULTS The two ADHD groups (ADHD, ADHD+RD) showed deficits in processing speed, naming of objects, poor behavioral inhibition and greater variability in reaction times whereas the two RD groups (RD, RD+ADHD) showed verbal working memory deficits and slower verbal retrieval speed. Only the comorbid group was slower with naming of numbers and colors and had slower reaction times. Regression analyses indicated that incongruent color naming (Stroop) and variability in go reaction time were the best predictors of hyperactive/impulsive ADHD symptoms whereas variability in go reaction time and processing speed were the best predictors of inattentive ADHD symptoms. Speed of letter naming and verbal working memory accounted for the most variability in composite achievement scores. No gender differences were found on any of the cognitive tests. CONCLUSIONS This study challenges the importance of behavioral inhibition deficits in ADHD and that naming deficits are specific to RD. Further investigation into cognitive deficits in these groups is required.
Near-infrared imaging of gigahertz-peaked-spectrum radio galaxies: tracing the evolution of giant ellipticals?

In this Letter we present K-band data for a sample of gigahertz-peaked-spectrum (GPS) radio galaxies. We show that the dispersion of the K-band Hubble diagram is small and comparable to that of the R-band Hubble diagram for these sources. The r - K colours of GPS galaxies evolve with redshift in agreement with models for both passively evolving and non-evolving elliptical galaxies. This behaviour indicates that the optical and infrared emission from these sources is dominated by starlight with little or no contamination by light from the active nuclei. At z ,. , 1 the absolute K­ band luminosities are about a magnitude fainter than expected for passively evolving ellipticals, just as in the case for radio-quiet giant ellipticals at similar redshifts. The lack of luminosity evolution may be caused by the dynamical evolution in the galaxies counteracting a change in the mass-to-light ratio of the systems: if the galaxies undergo mergers at z > 0.5, the high-redshift systems will be less massive than those at low redshift. In contrast to powerful radio sources in general, we believe that GPS radio galaxies are representative of early-type galaxies and may be excellent objects for studying the evolution of giant ellipticals at z > 1, given their relative ease of selection.
Reduction of Technetium by Desulfovibrio desulfuricans: Biocatalyst Characterization and Use in a Flowthrough Bioreactor

ABSTRACT Resting cells of Desulfovibrio desulfuricans coupled the oxidation of a range of electron donors to Tc(VII) reduction. The reduced technetium was precipitated as an insoluble low-valence oxide. The optimum electron donor for the biotransformation was hydrogen, although rapid rates of reduction were also supported when formate or pyruvate was supplied to the cells. Technetium reduction was less efficient when the growth substrates lactate and ethanol were supplied as electron donors, while glycerol, succinate, acetate, and methanol supported negligible reduction. Enzyme activity was stable for several weeks and was insensitive to oxygen. Transmission electron microscopy showed that the radionuclide was precipitated at the periphery of the cell. Cells poisoned with Cu(II), which is selective for periplasmic but not cytoplasmic hydrogenases, were unable to reduce Tc(VII), a result consistent with the involvement of a periplasmic hydrogenase in Tc(VII) reduction. Resting cells, immobilized in a flowthrough membrane bioreactor and supplied with Tc(VII)-supplemented solution, accumulated substantial quantities of the radionuclide when formate was supplied as the electron donor, indicating the potential of this organism as a biocatalyst to treat Tc-contaminated wastewaters.