Miracle-dz/UniFAR-FTUs huggingface dataset:
The frequency of common skin conditions in preschool-aged children in Australia: seborrheic dermatitis and pityriasis capitis (cradle cap).

OBJECTIVE To determine the prevalence and severity of seborrheic dermatitis and pityriasis capitis in Australian preschool-aged children. DESIGN A stratified cross-sectional skin survey using cluster sampling of centers throughout Victoria, Australia. SETTING The study population included children attending child care centers, preschools, and Maternal and Child Health Centers, with the reference population being Australian children 5 years and younger. PARTICIPANTS Of the 1,634 children in the original sample, 1.116 children aged 11 days to 5 years 11 months were included in the study. INTERVENTION Parents completed a questionnaire recording demographic information and personal and family history of skin problems and related diseases. A dermatologist performed a total skin examination, including the diaper area for children younger than 12 months. MAIN OUTCOME MEASURE The age- and sex-specific prevalence rates and site and severity of seborrheic dermatitis and pityriasis capitis were measured. RESULTS The overall age- and sex-adjusted prevalence of seborrheic dermatitis was 10.0% (95% confidence interval [CI], 8.2%-11.7%): 10.4% (95% CI, 7.8%-12.9%) in boys and 9.5% (95% CI, 7.0%-12.0%) in girls. This was highest in the first 3 months of life, decreasing rapidly by the age of 1 year, after which it slowly decreased over the next 4 years. Most (71.9%) had disease classified as minimal to mild. Pityriasis capitis occurred in 41.7% (95% CI, 38.8%-44.6%) of the 1,116 children examined, with 85.8% categorized as minimal to mild only. CONCLUSIONS Seborrheic dermatitis and pityriasis capitis are common in early childhood. Most children have minimal to mild disease that would require little if any treatment. Education programs directed at those caring for preschool-aged children are needed to provide information on simple preventative measures and treatment, if necessary, that could easily reduce the morbidity associated with these very common conditions.
A New System, the LipiFlow, for the Treatment of Meibomian Gland Dysfunction

Purpose To evaluate the safety and effectiveness of the LipiFlow System compared to the iHeat Warm Compress (WC) for adults with meibomian gland dysfunction (MGD). Methods This was a non-significant risk, prospective, open-label, randomized, crossover multicenter clinical trial. One hundred thirty-nine subjects were randomized between LipiFlow (n=69) and WC control (n=70). Subjects in the LipiFlow group received a 12-minute LipiFlow treatment and were reexamined at 1 day, 2 weeks and 4 weeks. Control subjects received a 5-minute iHeat treatment with instructions to perform the same treatment daily for 2 weeks. At 2 weeks, they crossed over (LipiFlow Crossover) and received the LipiFlow treatment. Effectiveness parameters: meibomian gland (MG) assessment, tear break-up time (TBUT) and dry eye symptoms. Safety parameters: adverse events, ocular health exam, ocular surface staining, intraocular pressure, visual acuity and discomfort. Results LipiFlow resulted in significant improvement (P < 0.05) in MG secretion at 2 and 4 weeks (mean ± standard deviation at baseline = 6.3 ± 3.5; 2 weeks = 14.3 ± 8.7; 4 weeks = 16.7 ± 8.7); and TBUT at 2 and 4 weeks: (at baseline = 5.5 ± 2.9; 2 weeks = 6.9 ± 5.0; 4 weeks = 7.4 ± 5.5). There was no significant change in MG secretion or TBUT in the control group. LipiFlow resulted in a greater significant reduction in dry eye symptoms than the iHeat WC. The crossover group demonstrated similar significant improvement 2 weeks post-treatment with the LipiFlow. There was no significant difference between groups in the incidence of non-serious, device-related adverse events. Conclusion The LipiFlow System was significantly more effective than iHeat WC. These results support its safety and effectiveness in the treatment of MGD and dry eye symptoms.
Four Core Social‐Psychological Motivations to Undertake Collective Action

Collective action against collective disadvantage is a theoretically and socially relevant phenomenon that has received increased scientific attention in recent years. Because recent work combines different theoretical traditions, the last decade can be rightly called an ‘age of integration’. In this article, I take stock and look ahead by briefly reviewing four core social-psychological motivations for undertaking collective action (based on identity, morality, emotion, and efficacy). I then review recent accumulating evidence for an encompassing social-psychological model of collective action that integrates all four core motivations. Based on this model's shortcomings, I close by calling for an ‘age of innovation’ for which I propose a theoretical and research agenda.
Striving for excellence: the role of top management team diversity in universities

Purpose – The purpose of this paper is to evaluate the influence of top management team diversity on academic excellence in universities. Academic excellence is conceptualized as successfully gaining funds for inter-organizational research collaborations, interdisciplinary graduate schools and high-ranked scientific reputation. Design/methodology/approach – The study applies upper echelon theory to universities. Three hypotheses are developed: (overall) top management team heterogeneity is positively associated with successful funding of excellence clusters, (overall) top management team heterogeneity is positively associated with successful funding of graduate schools and (overall) top management team heterogeneity is positively associated with academic reputation. The empirical study is based on a cross-sectional dataset with a time lag, covering characteristics of 75 German public universities from 2008 to 2013. Multiple-regression analysis is applied to test the hypotheses. Findings – Our results indi.
Running head : RANKS AND RIVALS Ranks and Rivals : A Theory of Competition

Social comparison theories typically assume a comparable degree of competition between commensurate rivals on a mutually important dimension. In contrast, however, the following set of studies reveals that the degree of competition between such rivals depends on their proximity to a standard. Studies 1 – 3 test the prediction that individuals become more competitive when they and their commensurate rivals are highly ranked (e.g., #2 vs. #3) than when they are not (e.g., #202 vs. #203). Studies 4 – 6 then generalize these findings, showing that the degree of competition increases not only for high ranks but also in the proximity of other meaningful standards, such as the bottom of a ranking scale or a qualitative threshold in the middle of a scale. Studies 7 – 8 further examine the psychological processes underlying the present findings and reveal that proximity to a meaningful standard exerts a direct impact on the “unidirectional drive upward. ”
Physiological Arousal and Time Estimation

The relations between four indices of arousal (heart rate, respiration rate, dominant EEG alpha rate, and an integrated score of EEG activity) and three methods of time estimation (verbal estimation, production, and tapping) were tested. 40 students, chosen according to their scores on the Taylor MAS, estimated short intervals under low and high (threat of shock) induced-arousal conditions. The data indicated relationships between dominant alpha rate and time estimation within each induced-arousal condition (thus supporting Hoagland's chemical clock hypothesis) and between heart rate and time estimation within the high induced-arousal condition. No significant differences in time estimation by any method between induced-arousal conditions were found. Physiological and psychological differences between induced and chronic arousal states are pointed out and the meaning of the results for the concept of arousal is discussed.
In Vivo Kinematics of the Tibiotalar Joint After Lateral Ankle Instability

Background Previous studies have suggested that injury to the anterior talofibular ligament (ATFL) may be linked to altered kinematics and the development of osteoarthritis of the ankle joint. However, the effects of ATFL injury on the in vivo kinematics of the ankle joint are unclear. Hypothesis Based on the orientation of the ATFL fibers, ATFL deficiency leads to increased anterior translation and increased internal rotation of the talus relative to the tibia. Study Design Descriptive laboratory study. Methods The ankles of 9 patients with unilateral ATFL injuries were compared as they stepped onto a level surface. Kinematic measurements were made as a function of increasing load. With use of magnetic resonance imaging and orthogonal fluoroscopy, the in vivo kinematics of the tibiotalar joint were measured in the ATFL-deficient and intact ankles of the same individuals. Results A statistically significant increase in internal rotation, anterior translation, and superior translation of the talus was measured in ATFL-deficient ankles, as compared with the intact contralateral controls. For example, at 100% body weight, ATFL-deficient ankles demonstrated an increase of 0.9 ± 0.5 mm in anterior translation (P = .008), an increase of 5.7° ± 3.6° in internal rotation (P = .008), and a slight increase of 0.2 ± 0.2 mm in the superior translation (P = .02) relative to the intact contralateral ankles. Conclusion Deficiency of the ATFL increases anterior translation, internal rotation, and superior translation of the talus. Clinical Relevance Altered kinematics may contribute to the degenerative changes observed with chronic lateral ankle instability. These findings might help to explain the degenerative changes frequently observed on the medial talus in patients with chronic ATFL insufficiency and so provide a baseline for improving ankle ligament reconstructions aimed at restoring normal joint motion.
Poor bullying prevention and employee health: some implications

Purpose – This paper aims to investigate employee reports of workplace bullying in which participants argue that poor management of bullying led to a range of health problems, both physical and mental.Design/methodology/approach – A constructivist approach is adopted to develop an understanding of individual experiences of bullying. Qualitative research interviews are used as the method of data collection and focus is on individual participants as the unit of analysis. Data are analyzed using thematic analysis in which both deductive and inductive themes are developed.Findings – Findings suggest that lack of or poor workplace bullying policies impacts are used negatively on employee health. Specifically, analysis of employee reports suggest that the inability to successfully report bullying, or have bullying complaints taken seriously leads to ongoing implications for the individual.Research implications – Future research needs to focus further on examining reasons why some organizations do not develop an.
The Sociology of Youth: A Reflection on Its Contribution to the Field and Future Directions

Johanna Wyn argues that there is a need for a sociological approach in relation to young people and family. The nexus between youth sociology and policy is a space where normative assumptions about the social meaning of age and the significance of intergenerational relationships need to be challenged. It is potentially a space into which the sociology of youth can contribute new thinking about the social meanings of age, the impact of social change on family relationships, generational consciousness and intergenerational relationships.
Prevalence of impacted and supernumerary teeth in the North Indian population

Objectives: Dental impaction is a very frequent problem. Supernumerary teeth, or hyperdontia, are the presence of additional teeth to the normal series in the either of the dentition. The presence of impacted and/or supernumerary teeth can cause various complications. The objective of the present study was to determine the prevalence of impacted and supernumerary teeth in the North Indian population. Study Design: The panoramic radiographic records of 4750 patients attending the Department of Oral Medicine and Radiology, Jodhpur Dental College General Hospital between September 2008 to December 2012 were examined for this retrospective study. The ages of the patients ranged from 8 to 72 years, with a mean of 34.6 years. Results: A total of 798 (16.8%) patients presented with 1126 impacted teeth. Impacted canines were the most prevalent (9.7%), followed by impacted premolars (4.3%). Supernumerary teeth (1.6%) and impacted molars (1.2%) were less prevalent. Among the 842 impacted teeth, the most frequently affected teeth were the canines (56.7%), followed by premolars (27.8%), and supernumerary teeth (9.3%), while the prevalence of impacted molars was quite lower (6.2%). Conclusion: The most frequently impacted teeth were maxillary canines and the mesiodens were the most common supernumerary tooth. The early diagnosis of supernumerary and impacted teeth is essential to prevent malocclusion and malalignment of permanent teeth demonstrating the importance of panoramic radiographs in their detection. Key words:Impacted, supernumerary, prevalence, canines, mesiodens.
Large-Scale Embedding Learning in Heterogeneous Event Data

Heterogeneous events, which are defined as events connecting strongly-typed objects, are ubiquitous in the real world. We propose a HyperEdge-Based Embedding (Hebe) framework for heterogeneous event data, where a hyperedge represents the interaction among a set of involving objects in an event. The Hebe framework models the proximity among objects in an event by predicting a target object given the other participating objects in the event (hyperedge). Since each hyperedge encapsulates more information on a given event, Hebe is robust to data sparseness. In addition, Hebe is scalable when the data size spirals. Extensive experiments on large-scale real-world datasets demonstrate the efficacy and robustness of Hebe.
Bayesian inference for agreement measures

ABSTRACT The agreement of different measurement methods is an important issue in several disciplines like, for example, Medicine, Metrology, and Engineering. In this article, some agreement measures, common in the literature, were analyzed from a Bayesian point of view. Posterior inferences for such agreement measures were obtained based on well-known Bayesian inference procedures for the bivariate normal distribution. As a consequence, a general, simple, and effective method is presented, which does not require Markov Chain Monte Carlo methods and can be applied considering a great variety of prior distributions. Illustratively, the method was exemplified using five objective priors for the bivariate normal distribution. A tool for assessing the adequacy of the model is discussed. Results from a simulation study and an application to a real dataset are also reported.
The beneficial role of anti-inflammatory dietary ingredients in attenuating markers of chronic low-grade inflammation in aging

Abstract Aging in humans is associated with chronic low-grade inflammation (systemic), and this condition is sometimes referred to as “inflammaging”. In general, canines also age similarly to humans, and such aging is associated with a decline in mobility, joint problems, weakened muscles and bones, reduced lean body mass, cancer, increased dermatological problems, decline in cognitive ability, reduced energy, decreased immune function, decreased renal function, and urinary incontinence. Each of these conditions is also associated with an increase in pro-inflammatory cytokines. An inflammatory state characterized by an increase in pro-inflammatory markers including but not restricted to tumor necrosis factor-α, interleukin-6, IL-1β, and C-reactive protein (CRP) is believed to contribute to or worsen a general decline in biological mechanisms responsible for physical function with aging. Nutritional management of inflammation in aging dogs is important in maintaining health. In particular, natural botanicals have bioactive components that appear to have robust anti-inflammatory effects and, when included in the diet, may contribute to a reduction in inflammation. While there are scientific data to support the anti-inflammatory effects and the efficacy of such bioactive molecules from botanicals, the clinical data are limited and more studies are needed to validate the efficacy of these ingredients. This review will summarize the role of dietary ingredients in reducing inflammatory molecules as well as review the evidence available to support the role of diet and nutrition in reducing chronic low-grade systemic inflammation in animal and human studies with a special reference to canines, where possible.
Binary Trees Implementations Comparison for Multicore Programming

Although there are a lot of optimized concurrent algorithms for lists, queues, stacks, hash tables and other common data structures, there are much fewer optimized concurrent Binary Search Trees implementations. This paper compares several concurrent implementations of Binary Search Tree. The implementations are also compared to a concurrent skip list, which is the general way to implement a concurrent set or map. All the data structures are implemented in C++ using Hazard Pointers to manage memory. The different implementations are compared using several measures to determine the best performing structures in different situations. The benchmark shows that some data Binary Search Tree implementations are performing much better than the concurrent skip list base implementation. The optimistic AVL Tree that has been tested is shown to be performing very well. Baptiste Wicht Computer Science Master degree Switzerland HES-SO University of applied science Baptiste Wicht 1 of 69 June 7, 2012
Dabigatran versus warfarin in the treatment of acute venous thromboembolism.

BACKGROUND The direct oral thrombin inhibitor dabigatran has a predictable anticoagulant effect and may be an alternative therapy to warfarin for patients who have acute venous thromboembolism. METHODS In a randomized, double-blind, noninferiority trial involving patients with acute venous thromboembolism who were initially given parenteral anticoagulation therapy for a median of 9 days (interquartile range, 8 to 11), we compared oral dabigatran, administered at a dose of 150 mg twice daily, with warfarin that was dose-adjusted to achieve an international normalized ratio of 2.0 to 3.0. The primary outcome was the 6-month incidence of recurrent symptomatic, objectively confirmed venous thromboembolism and related deaths. Safety end points included bleeding events, acute coronary syndromes, other adverse events, and results of liver-function tests. RESULTS A total of 30 of the 1274 patients randomly assigned to receive dabigatran (2.4%), as compared with 27 of the 1265 patients randomly assigned to warfarin (2.1%), had recurrent venous thromboembolism; the difference in risk was 0.4 percentage points (95% confidence interval [CI], -0.8 to 1.5; P<0.001 for the prespecified noninferiority margin). The hazard ratio with dabigatran was 1.10 (95% CI, 0.65 to 1.84). Major bleeding episodes occurred in 20 patients assigned to dabigatran (1.6%) and in 24 patients assigned to warfarin (1.9%) (hazard ratio with dabigatran, 0.82; 95% CI, 0.45 to 1.48), and episodes of any bleeding were observed in 205 patients assigned to dabigatran (16.1%) and 277 patients assigned to warfarin (21.9%; hazard ratio with dabigatran, 0.71; 95% CI, 0.59 to 0.85). The numbers of deaths, acute coronary syndromes, and abnormal liver-function tests were similar in the two groups. Adverse events leading to discontinuation of the study drug occurred in 9.0% of patients assigned to dabigatran and in 6.8% of patients assigned to warfarin (P=0.05). CONCLUSIONS For the treatment of acute venous thromboembolism, a fixed dose of dabigatran is as effective as warfarin, has a safety profile that is similar to that of warfarin, and does not require laboratory monitoring. (ClinicalTrials.gov number, NCT00291330.)
Automated detection of discourse segment and experimental types from the text of cancer pathway results sections

Automated machine-reading biocuration systems typically use sentence-by-sentence information extraction to construct meaning representations for use by curators. This does not directly reflect the typical discourse structure used by scientists to construct an argument from the experimental data available within a article, and is therefore less likely to correspond to representations typically used in biomedical informatics systems (let alone to the mental models that scientists have). In this study, we develop Natural Language Processing methods to locate, extract, and classify the individual passages of text from articles’ Results sections that refer to experimental data. In our domain of interest (molecular biology studies of cancer signal transduction pathways), individual articles may contain as many as 30 small-scale individual experiments describing a variety of findings, upon which authors base their overall research conclusions. Our system automatically classifies discourse segments in these texts into seven categories (fact, hypothesis, problem, goal, method, result, implication) with an F-score of 0.68. These segments describe the essential building blocks of scientific discourse to (i) provide context for each experiment, (ii) report experimental details and (iii) explain the data’s meaning in context. We evaluate our system on text passages from articles that were curated in molecular biology databases (the Pathway Logic Datum repository, the Molecular Interaction MINT and INTACT databases) linking individual experiments in articles to the type of assay used (coprecipitation, phosphorylation, translocation etc.). We use supervised machine learning techniques on text passages containing unambiguous references to experiments to obtain baseline F1 scores of 0.59 for MINT, 0.71 for INTACT and 0.63 for Pathway Logic. Although preliminary, these results support the notion that targeting information extraction methods to experimental results could provide accurate, automated methods for biocuration. We also suggest the need for finer-grained curation of experimental methods used when constructing molecular biology databases
Minimax Manifold Estimation

We find the minimax rate of convergence in Hausdorff distance for estimating a manifold M of dimension d embedded in R^D given a noisy sample from the manifold. We assume that the manifold satisfies a smoothness condition and that the noise distribution has compact support. We show that the optimal rate of convergence is n^{-2/(2+d)}. Thus, the minimax rate depends only on the dimension of the manifold, not on the dimension of the space in which M is embedded.
The theory of sex allocation.

This book is the first comprehensive treatment of sex allocation from the standpoint of modern evolutionary theory. It shows how the determination of sex ratio, resource allocation to sperm versus egg within simultaneous hermaphroditism, and the evolution of sex reversal can he explained as examples of a single process. The genetical theory, developed mostly with graphical arguments, also specifies when hermaphroditism and dioecy are themselves evolutionary stable. The work balances theory with field and laboratory research, providing critical tests of the theory by empirical studies of sex ratio in parasitoid wasps and mites, sex reversal in shrimp and coral reef fish, and allocation of resources to pollen versus seeds in higher plants. In addition, the author oilers an encyclopedic review of the field and laboratory work of other scientists, reviews many as yet untested hypotheses in sex allocation, and points toward numerous plant and animal systems that hold promise for future tests.