Miracle-dz/UniFAR-FTUs huggingface dataset:
Girls’ friendships as habitus in an elite, middle-class secondary school in Ireland

ABSTRACT This study examines gendered and classed friendships in a predominantly middle-class, girls' secondary school in the southern region of the Republic of Ireland. Bourdieu's (1977) concept of habitus, interactively, with Gidden's (1984) concept of practical consciousness, and Gambetta's (1987) intentional rational choice informed the conceptual framework for the study. Narrative sources yielded data about girls' friendships and peer interactions inside and outside of school. The social class and habitus of each of the girls mediated their friendship formation and friendship choice. Data sources highlight that the middle-class girls' friendships were situated in fluid and multiple cliques; given their hegemonic positionality within the school. Contrastingly, working-class girls' friendships were situated in a contained and single clique, often evidenced by their resistance to the institutional habitus. The ways in which these peer friendships operated as powerful shapers of the girls' actions and identities is discussed. This paper provides examples of the nuanced ways that girls' friendships are developed and maintained based on conformity or resistance to the school norms and expectations of academic success. Importantly, findings evidence the differentiated and instrumental use of friendships among the middle-class and working-class girls in a competitive, elite school setting.
Pairwise Tensor Factorization for learning new facts in Knowledge Bases

Knowledge bases provide with the benet of organizing knowledge in the relational form but suer from incompleteness of new entities and relationships. Prior work on relation extraction has been focused on supervised learning techniques which are quite expensive. An alternative approach based on distant supervision has been of signicant interest where one aligns database records with sentences of these records. A new line of work on embeddings of symbolic representations [2] has shown promise. We introduce a Matrix trifactorization model which can nd missing information in knowledge bases. Experiments show that we are able to query and nd missing information from text and shows improvement over existing methods.
Finite Horizon, Externalities, and Growth

This paper investigates the impact of externalities on economic growth in an AK model. In contrast to the existing literature, the paper considers finitely-lived agents along the continuous time, overlapping generations literature. A series of new results, not holding for infinitely-lived agent economies, emerge. Consumption externalities generally introduce a distortion (inefficiency), even when labor supply is exogenous and there is no concurrent production externality. A negative consumption externality implies overconsumption, and growth is lower than optimal. Transition paths are considered. The model employed encompasses the infinitely-lived agent economy as a special case, thus helps understanding the differences in results between finite-horizon overlapping-generations and infinitely-lived agents economies.
Inhibition by a retinoic acid receptor γ agonist of extracellular matrix remodeling mediated by human Tenon fibroblasts

Purpose Scar formation is most frequently responsible for the failure of glaucoma filtration surgery. Retinoic acids are vitamin A derivatives that play diverse roles in development, immunity, and tissue repair. The effects of the retinoic acid receptor (RAR) γ agonist R667 on the contractility of human Tenon fibroblasts (HTFs) cultured in a three-dimensional collagen gel as well as on intraocular pressure (IOP) in a rat model of glaucoma filtration surgery were investigated. Methods HTFs were cultured in a type I collagen gel, the contraction of which was evaluated by measurement of the gel diameter. The release of matrix metalloproteinases (MMPs) into culture supernatants was assessed with immunoblot analysis and gelatin zymography. Phosphorylation of focal adhesion kinase (FAK) was examined with immunoblot analysis, and production of fibronectin and type I collagen was measured with immunoassays. Results R667 inhibited transforming growth factor-β1 (TGF-β1)-induced collagen gel contraction mediated by HTFs in a concentration- and time-dependent manner, whereas an RARα agonist inhibited this process to a lesser extent and an RARβ agonist had no effect. TGF-β1-induced MMP-1 and MMP-3 release, FAK phosphorylation, and fibronectin and type I collagen production in HTFs were also attenuated by R667. Furthermore, R667 lowered IOP in rats after glaucoma filtration surgery. Conclusions R667 inhibited TGF-β1-induced contraction and extracellular matrix synthesis in HTFs. Such effects might have contributed to the lowering of IOP by R667 in a rat model of glaucoma filtration surgery. RARγ agonists might thus prove effective for inhibition of scar formation after such surgery.
Influence Of Joint Television Viewing On Romantic Satisfaction And Family Commitment: A Study Of Spouses In Delta State Secretariat Complex Asaba

The subject of this research is the influence of joint television viewing on the romantic satisfaction and family commitment of spouses in Delta State Secretariat Complex, Asaba, Delta state. The study adopted the purposive sampling method also known as judgmental sampling. The instrument of data collection was the interview guide. One hundred and twenty six (126) spouses were purposively selected and studied in this work. All the respondents were individually subjected to an average of 30 minutes long in-depth interview conducted over a period of three (3) months. The cultivation theory and the uses and gratifications theory served as the guiding theories for the study. The major objective of the study was to assess the influence of joint television viewing of programmes on the romantic satisfaction and family commitment of spouses in the secretariat. The result showed a great correlation between joint television viewing of love related programmes and the romantic satisfaction as well as family commitment of spouses in the secretariat complex. However, this degree of correlation was absent in the case of joint television viewing of other programmes that are not love related. Therefore, the paper recommends, among others, that spouses should selectively expose themselves to love stories that teach selfless love and sacrifice rather than those with default story lines that tend to be acrimonious and divisive of couples.
Progressive Hulls : Application on Biomedical Data

A coarse outer hull of a mesh is a good tool used in computer graphics to reduce algorithm complexity, especially, in applications such as collision detection or ray-tracing. It is often required that the hull has some very specific parameters concerning its shape and quality since these influence general flexibility and numerical stability of the algorithms. This paper overviews existing problem approaches, their downsides for coarse outer hull creation, and describes Progressive Hull algorithm, which produces coarse hulls that maintain the general shape of the original triangulated mesh while containing the original mesh inside its interior. However, when this algorithm is used on a biomedical mesh extracted from volumetric data, one can observe frequent artifacts in the produced hull caused by local imperfections in the meshes. In this paper, we, therefore, present a few modifications to the original Progressive Hull algorithm that result not only in a suppression of hull artifacts and a better overall hull quality but also in a shorter execution time.
LIN28B Promotes Colon Cancer Migration and Recurrence

LIN28B is involved in “stemness” and tumourigenesis by negatively regulating the maturation of let-7 microRNA family members. In this study, we showed that LIN28B expression promotes migration and recurrence of colon cancer. Immunohistochemistry and reverse-transcription polymerase chain reactions were performed to detect LIN28B expression in colon cancer tissue microarrays, paraffin-embedded surgical resected tissues and cancer cells. Loss-of-function, migration and proliferation analyses were performed to delineate the potential roles of LIN28B in colon cancer. LIN28B was upregulated in colon cancer tissue compared to normal mucosa, and its overexpression correlated with reduced patient survival and increased tumour recurrence. LIN28B suppression inhibited the migration of SW480 colon cancer cells and facilitated the cytotoxicity induced by oxaliplatin in SW480 and HCT116 colon cancer cells. In conclusion, LIN28B overexpression contributes to colon tumourigenesis, and LIN28B may serve as a diagnostic tool and therapeutic target for colon cancer.
Current status of renal and urinary proteomics: ready for routine clinical application?

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Hippocampal Atrophy Relates to Fluid Intelligence Decline in the Elderly

Abstract Measures of brain and hippocampal volume in 40 healthy young (aged 18–30 years) and 36 healthy elderly (aged 60–83 years) subjects were compared with composite cognitive function scores in three conceptual domains: memory ability, processing speed, and general fluid intelligence. Through a series of general linear models testing the relationship between these brain measures and cognitive performance scores, a significant positive relationship between hippocampal volume and fluid intelligence ability was found in elderly subjects but not in young. No relationship between the other cognitive domains and brain or hippocampal volume was found. The findings suggest a role of hippocampal atrophy in the decline in fluid intelligence in the elderly. (JINS, 2011, 17, 000–000)
The RSA Algorithm

In public key cryptography, messages are encoded using a public key E and decoded using a private key D. Any agent A who wants to receive secret messages obtains a key pair (EA, DA). The agent A keeps the private key DA secret and publishes the public key EA, say on a webpage. Now if agent B wants to send a secret messagem to A, B encodes the plaintext message m using A’s public key to get an encoded ciphertext EA(m). The ciphertext is sent to the recipient, who can decode it using the private key to get DA(EA(m)) = m. For this to work, it must be the case that DA is a left inverse of EA, that is, DA ◦EA is the identity function. For it to be secure, it must be the case that neither the plaintext message nor the private key can be derived from knowledge of the ciphertext or the public key.
Cosmological deuterium abundance and the baryon density of the universe

Standard big bang nucleosynthesis (BBNS) promises accurate predictions of the primordial abundances of deuterium, helium-3, helium-4 and lithium-7 as a function of a single parameter. Previous measurements have nearly always been interpreted as confirmation of the model (Copi, Schramm & Turner 1995). Here we present a measurement of the deuterium to hydrogen ratio (D/H) in a newly discovered high redshift metal-poor gas cloud at redshift $z=2.504$. This confirms our earlier measurement of D/H (Tytler, Fan & Burles 1996), and together they give the first accurate measurement of the primordial D abundance, and a ten fold improvement in the accuracy of the cosmological density of ordinary matter.This is a high density, with most ordinary matter unaccounted or dark, which is too high to agree with measurements of the primordial abundances of helium-4 and lithium-7. Since the D/H measurement is apparently simple, direct, accurate and highly sensitive, we propose that helium requires a systematic correction, and that population II stars have less than the primordial abundance of $^7$Li. Alternatively, there is no concordance between the light element abundances, and the simple model of the big bang must be incomplete and lacking physics, or wrong.
Inferring population connectivity across the range of distribution of the stiletto shrimp Artemesia longinaris Spence Bate, 1888 (Decapoda, Penaeidae) from DNA barcoding: implications for fishery management

Abstract Artemesia longinaris is a marine shrimp endemic to the southwestern Atlantic and distributed from Atafona, Rio de Janeiro (Brazil) to Rawson, Chubut (Argentina). In recent years, this species has become an important target of the commercial fishery as a consequence of the decline in the fishery of more traditional and profitable marine shrimps. In addition, phenotypic variations have been documented in populations along its distribution. Therefore, investigations on the genetics of the fishing stocks are necessary for the development of sustainable management strategies and for understanding the possible sources of these variations. The mitochondrial gene Cytochrome Oxidase I (COI) was used to search for evidence of genetic structure among the populations of Artemesia longinaris and to analyze the phylogenetic relationships among them. A total of 60 specimens were collected from seven different localities, covering its geographical range. The final alignment showed 53 haplotypes (48 individuals and 5 shared), with no biogeographical pattern. The low genetic divergence found, with a non-significant FST value, also suggests the absence of population structure for this gene. These findings indicate a continuous gene flow among the populations analyzed, suggesting that the phenotypic variation is a consequence of different environmental conditions among the localities.
Constraints on the Delayed Transition to Detonation in Type Ia Supernovae

We investigate the possibility of a delayed detonation in a Type Ia supernova under the assumption that the transition to detonation is triggered by turbulence only. Our discussion is based on the Zeldovich mechanism and suggests that typical turbulent velocities present during the explosion are not strong enough to allow this transition to occur. Although we are able to show that in carbon-rich matter (e.g., X(12C) = 0.75) the possibility of a deflagration to detonation transition (DDT) is enhanced, even in this case, the turbulent velocities needed are larger than the expected value of u′(L) ≈ 107 cm s-1 on a length-scale of L ≈ 106 cm. Thus we conclude that a DDT may not be a common event during a thermonuclear explosion of a Chandrasekhar-mass white dwarf.
Evaluation of the “e-Daftar” System Using the Technology Acceptance Model (TAM)

Diverse management information systems have been developed to meet organisations’ needs and fulfil their strategic management functions. These include NIOSH, which uses e-Daftar: a training-related information management system developed by the Information Technology Division of NIOSH. This study aims to measure the level of acceptance of the e-Daftar system among NIOSH employees, and its effectiveness. The Acceptance Technology Model (TAM), with the independent variables of perceived usefulness (PU), perceived ease of use (PEOU), and attitude towards using (ATU) is the basis of analysis. This study is a descriptive survey using a quantitative approach. A total of 180 participants were involved, comprising NIOSH staff who use the e-Daftar system, and 126 samples, obtained using the Krejcie and Morgan methods, were analysed. Questionnaires were distributed online using the Question Pro application, and analysed using the Statistical Package for Social Science (SPSS) v23.0. The results show that the perception of ease of use has a significant relationship with attitudes to the use of the e-Daftar system. In addition, regression test results indicate that the perception of usefulness and perceived ease of use has a positive effect on attitudes to the use of e-Daftar, and perceived ease of use is the most significant predictor of attitudes toward consumption. In conclusion, the use of e-Daftar is very effective for the purpose of information management training when the level of user acceptance of the system is high. This study is expected to provide suggestions for improvements to existing applications, as well as reference material for future research.
Brain Arterial Diameters as a Risk Factor for Vascular Events

Background Arterial luminal diameters are routinely used to assess for vascular disease. Although small diameters are typically considered pathological, arterial dilatation has also been associated with disease. We hypothesize that extreme arterial diameters are biomarkers of the risk of vascular events. Methods and Results Participants in the Northern Manhattan Study who had a time-of-flight magnetic resonance angiography were included in this analysis (N=1034). A global arterial Z-score, called the brain arterial remodeling (BAR) score, was obtained by averaging the measured diameters within each individual. Individuals with a BAR score <−2 SDs were considered to have the smallest diameters, individuals with a BAR score >−2 and <2 SDs had average diameters, and individuals with a BAR score >2 SDs had the largest diameters. All vascular events were recorded prospectively after the brain magnetic resonance imaging. Spline curves and incidence rates were used to test our hypothesis. The association of the BAR score with death (P=0.001), vascular death (P=0.02), any vascular event (P=0.05), and myocardial infarction (P=0.10) was U-shaped except for ischemic stroke (P=0.74). Consequently, incidence rates for death, vascular death, myocardial infarction, and any vascular event were higher in individuals with the largest diameters, whereas individuals with the smallest diameters had a higher incidence of death, vascular death, any vascular event, and ischemic stroke compared with individuals with average diameters. Conclusions The risk of death, vascular death, and any vascular event increased at both extremes of brain arterial diameters. The pathophysiology linking brain arterial remodeling to systemic vascular events needs further research.
Sponsored search: A brief history

La recherche sponsorisee sur le Web, qui permet aux annonceurs de faire apparaitre leurs contenus dans les resultats affiches par un moteur de recherche, a demarre en 1998 avec GoTo, acquis par Yahoo! en 2002. Le prix de l'apparition sur un site donne peut etre fonction du nombre d'apparitions (cout pour mille), des clicks sur un lien (cout par click) ou des actes engendres (cout par action). La recherche payee souleve un interet grandissant au sein de la communaute academique.
Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein

Assembly of muscle sarcomeres is a complex dynamic process and involves a large number of proteins. A growing number of these have regulatory functions and are transiently present in the myofibril. We show here that the novel tubulin-associated RING/B-box protein MURF2 associates transiently with microtubules, myosin and titin during sarcomere assembly. During sarcomere assembly, MURF2 first associates with microtubules at the exclusion of tyrosinated tubulin. Then, MURF2-labelled microtubules associate transiently with sarcomeric myosin and later with A-band titin when non-striated myofibrils differentiate into mature sarcomeres. Finally, MURF2 labelled microtubules disappear from the sarcomere after the incorporation of myosin filaments and the elongation of titin. This suggests that the incorporation of myosin into nascent sarcomeres and the elongation of titin require an active, microtubule-dependent transport process and that MURF2-associated microtubules play a role in the alignment and extension of nascent sarcomeres. MURF2 is expressed in at least four isoforms, of which a 27 kDa isoform is cardiac specific. A C-terminal isoform is generated by alternative reading frame use, a novelty in muscle proteins. In mature cardiac sarcomeres, endogenous MURF2 can associate with the M-band, and is translocated to the nucleus. MURF2 can therefore act as a transient adaptor between microtubules, titin and nascent myosin filaments, as well as being involved in signalling from the sarcomere to the nucleus.
Organisational downsizing and increased use of psychotropic drugs among employees who remain in employment

Objective: Organisational downsizing is common in modern work life, but its effect on employees’ mental health is not known. The authors examined whether working in downsizing organisations predicts use of psychotropic drugs among employees who remain in employment. Design, setting and participants: Prospective cohort study of municipal employees in Finland. 4783 employees worked in downsized units but kept their jobs after downsizing in 1993, 4271 employees lost their jobs during the downsizing, and 17 599 employees did not experience downsizing. The outcome was psychotropic drug prescriptions (antidepressants, anxiolytics and hypnotics) during 1994–2000 extracted from nationwide registers and linked to the data by means of each participant’s personal identification number. Main results: After adjustment for predownsizing characteristics, employees who were exposed to downsizing but kept their jobs were at a higher risk of being prescribed psychotropic drugs (rate ratio 1.49, 95% CI 1.10 to 2.02 in men and 1.12, 95% CI 1.00 to 1.27 in women) than those not exposed to downsizing. The association of downsizing was strongest with hypnotics among the men and with anxiolytics among the women. An increased rate of psychotropic prescriptions after downsizing was also seen in male workers who lost their job (rate ratio 1.64, 95% CI 1.19 to 2.25). Conclusions: The association between organisational downsizing and increased use of psychotropic drugs suggests that this managerial strategy may pose mental health risks among employees.