Miracle-dz/UniFAR-FTUs huggingface dataset:
Urban Vibrancy and Corporate Growth

We find that a firm's investment is highly sensitive to the investments of other firms headquartered nearby, even those in very different industries. It also responds to fluctuations in the cash flows and stock prices (q) of local firms outside its sector. These patterns do not appear to reflect exogenous area shocks such as local shocks to labor or real estate values, but rather suggest that local agglomeration economies are important determinants of firm investment and growth.
Distinct patterns of tau-dependent process formation in mammalian cell lines

Tau is a microtubule-associated protein involved in axonal elongation and central to the pathogenesis of a number of neurodegenerative conditions. To better establish the contribution of the cellular context to tau-dependent microtubule organization, we compared the phenotypes resulting from heterologous tau expression in different mammalian cell lines after disruption of the actin cytoskeleton. After cytochalasin D treatment, tau-expressing CHO cells display one or two long neurite-like extensions whereas cells transfected with MAP2c developed multiple shorter processes. By contrast, under the same conditions, tau-transfected PtK2 cells elaborate microtubule bundles forming numerous processes. These results suggest that cell-specific factors are involved in tau-dependent microtubule organization, a notion that could facilitate functional assessment of tau abnormalities associated with neurodegenerative disease.
Compact Tri-Band Bandpass and Bandstop Filters Based on Hilbert-Fork Resonators

In this work, a multi-mode Hilbert-fork resonator consisting of two dual-mode resonators is presented. The behavior of the proposed configuration is analyzed in detail. To demonstrate the potential of the proposed resonator, tri-band bandpass and bandstop filters operating at 2.4/3.5/5.2 GHz have been designed, fabricated and measured. Both filters are characterized by good performances and very compact size of only 0. 21λ<i>g</i> × 0. 11λ<i>g</i> and 0. 22λ<i>g</i> × 0. 1λ<i>g</i> , respectively.
TIME-SCALING FOR SLOW MOTION SPORTS VIDEOS

Slow motion videos are frequently featured during broadcast of sports events. However, these videos do not feature any audio channel, apart from the live ambiance and comments from sports presenters. Standard audio time-scaling methods were not developed with such noisy signal in mind and they do not always permit to obtain an acceptable acoustic quality. In this work, we present a new approach that creates high-quality time-stretched version of sport audio recordings while preserving all their transient events.
Detecting duplicate web documents using clickthrough data

The web contains many duplicate and near-duplicate documents. Given that user satisfaction is negatively affected by redundant information in search results, a significant amount of research has been devoted to developing duplicate detection algorithms. However, most such algorithms rely solely on document content to detect duplication, ignoring the fact that a primary goal of duplicate detection is to identify documents that contain redundant information with respect to a particular user query. Similarly, although query-dependent result diversification algorithms compute a query-dependent ranking, they tend to do so on the basis of a query-independent content similarity score. In this paper, we bridge the gap between query-dependent redundancy and query-independent duplication by showing how user click behavior following a query provides evidence about the relative novelty of web documents. While most previous work on interpreting user clicks on search results has assumed that they reflect just result relevance, we show that clicks also provide information about duplication between web documents since users consider search results in the context of previously seen documents. Moreover, we find that duplication explains a substantial amount of presentation bias observed in clicking behavior. We identify three distinct types of redundancy that commonly occur on the web and show how click data can be used to detect these different types.
In Vivo Antiprotozoal Activity of the Chloroform Extract from Carica papaya Seeds against Amastigote Stage of Trypanosoma cruzi during Indeterminate and Chronic Phase of Infection

In order to evaluate the antiprotozoal activity of the chloroform extract of Carica papaya seeds during the subacute and chronic phase of infection of Trypanosoma cruzi, doses of 50 and 75 mg/kg were evaluated during the subacute phase, including a mixture of their main components (oleic, palmitic, and stearic acids). Subsequently, doses of 50 and 75 mg/kg in mice during the chronic phase of infection (100 dpi) were also evaluated. It was found that chloroform extract was able to reduce the amastigote nests numbers during the subacute phase in 55.5 and 69.7% (P > 0.05) as well as in 56.45% in animals treated with the mixture of fatty acids. Moreover, the experimental groups treated with 50 and 75 mg/kg during the chronic phase of the infection showed a significant reduction of 46.8 and 53.13% respectively (P < 0.05). It is recommended to carry out more studies to determine if higher doses of chloroformic extract or its administration in combination with other antichagasic drugs allows a better response over the intracellular stage of T. cruzi in infected animal models and determine if the chloroform extract of C. papaya could be considered as an alternative for treatment during the indeterminate and chronic phase of the infection.
Generation and Maintenance of Gradients in Taxonomic Diversity

Latitudinal gradients in diversity of organisms represent an equilibrium distribution for at least the last 270 x 106 years. Faunas endemic to tropical regions evolved significantly faster than extra-tropical faunas. The latitude-dependent difference in rates of evolution also represents an equilibrium condition for at least the last 270 x 106 years and has consequences for paleontological correlation of rocks because the attainable resolution depends on rate of evolution and will thus be greater in tropic regions than in extra-tropical ones.
STIFFNESS MEASUREMENTS ON AN UNSATURATED HIGH PLASTICITY CLAY USING BENDER ELEMENTS

This paper describes the results of a series of bender element tests carried out on statically compacted high plasticity London Clay. Four specimens were compacted at different initial water contents and void ratios and subsequently allowed to dry gradually until air-dry. Measurements of shear modulus (using bender elements) and matrix suction (using the filter paper technique), together with water content and void ratio, were made at various stages during the drying process. The techniques used are described and discussed. (A) For the covering abstract see IRRD 881647.
A mechanism for the control of crack propagation in all-brittle systems

The stress distribution close to the tip of a crack which has a finite tip radius and which is being opened either by means of a remotely applied tension field σy, 0 or by means of a concentrated force (e. g. a wedge driven into the crack) has been computed. It is shown that there exist tensile stresses (σx) parallel to the plane of the crack and ahead of the crack tip. The maximum value of the tension σx is an approximately constant fraction (~ 1/5) of the peak stress concentration σy, max. which usually causes crack propagation. Inside a brittle solid, if a plane of weakness or potential cleavage is present and is roughly normal to the plane of the original crack, this interface may break and produce a secondary crack in such a manner as to interfere with the progress of the primary crack. If the ratio of the adhesive strength of the interface to the general cohesive strength of the solid is in the right range large increases in the strength and toughness of otherwise brittle solids may result.
Diminishing Returns Epistasis Among Beneficial Mutations Decelerates Adaptation

Interactions between genes reduce the benefits of a mutation and decrease the rate of fitness gain during adaptation. Epistasis has substantial impacts on evolution, in particular, the rate of adaptation. We generated combinations of beneficial mutations that arose in a lineage during rapid adaptation of a bacterium whose growth depended on a newly introduced metabolic pathway. The proportional selective benefit for three of the four loci consistently decreased when they were introduced onto more fit backgrounds. These three alleles all reduced morphological defects caused by expression of the foreign pathway. A simple theoretical model segregating the apparent contribution of individual alleles to benefits and costs effectively predicted the interactions between them. These results provide the first evidence that patterns of epistasis may differ for within- and between-gene interactions during adaptation and that diminishing returns epistasis contributes to the consistent observation of decelerating fitness gains during adaptation.
Gene transfer into mouse lyoma cells by electroporation in high electric fields.

Electric impulses (8 kV/cm, 5 microseconds) were found to increase greatly the uptake of DNA into cells. When linear or circular plasmid DNA containing the herpes simplex thymidine kinase (TK) gene is added to a suspension of mouse L cells deficient in the TK gene and the cells are then exposed to electric fields, stable transformants are formed that survive in the HAT selection medium. At 20 degrees C after the application of three successive electric impulses followed by 10 min to allow DNA entry there result 95 (+/‐ 3) transformants per 10(6) cells and per 1.2 micrograms DNA. Compared with biochemical techniques, the electric field method of gene transfer is very simple, easily applicable, and very efficient. Because the mechanism of DNA transport through cell membranes is not known, a simple physical model for the enhanced DNA penetration into cells in high electric fields is proposed. According to this ‘electroporation model’ the interaction of the external electric field with the lipid dipoles of a pore configuration induces and stabilizes the permeation sites and thus enhances cross membrane transport.
Ductal Closure With Paracetamol: A Surprising New Approach to Patent Ductus Arteriosus Treatment

Standard pharmacologic closure of the patent ductus arteriosus currently involves the administration of 1 of 2 cyclooxygenase inhibitors: either indomethacin or ibuprofen. However, both of these drugs can be associated with potentially significant adverse effects. We present here the cases of 5 preterm infants (gestational age: 26–32 weeks; postnatal age: 3–35 days) with large, hemodynamically significant patent ductus arteriosus who had either failed or had contraindications to ibuprofen therapy. Each of these infants was treated with off-label oral paracetamol (15 mg/kg per dose every 6 hours). Ductal closure was achieved within 48 hours in all the treated infants. No toxicity was observed.
Symmetry-Aware Nonrigid Matching of Incomplete 3D Surfaces

We present a nonrigid shape matching technique for establishing correspondences of incomplete 3D surfaces that exhibit intrinsic reflectional symmetry. The key for solving the symmetry ambiguity problem is to use a point-wise local mesh descriptor that has orientation and is thus sensitive to local reflectional symmetry, e.g. discriminating the left hand and the right hand. We devise a way to compute the descriptor orientation by taking the gradients of a scalar field called the average diffusion distance (ADD). Because ADD is smoothly defined on a surface, invariant under isometry/scale and robust to topological errors, the robustness of the descriptor to non-rigid deformations is improved. In addition, we propose a graph matching algorithm called iterative spectral relaxation which combines spectral embedding and spectral graph matching. This formulation allows us to define pairwise constraints in a scale-invariant manner from k-nearest neighbor local pairs such that non-isometric deformations can be robustly handled. Experimental results show that our method can match challenging surfaces with global intrinsic symmetry, data incompleteness and non-isometric deformations.
Habitat diversity and ecosystem multifunctionality—The importance of direct and indirect effects

Both habitat diversity and species diversity are important factors in ecosystem productivity and nutrient cycling. Ecosystems worldwide are facing habitat homogenization due to human activities. Although it is commonly proposed that such habitat homogenization can have negative repercussions for ecosystem functioning, this question has yet to receive explicit scientific attention. We expand on the framework for evaluating the functional consequences of biodiversity loss by scaling up from the level of species to the level of the entire habitats. Just as species diversity generally fosters ecosystem functioning through positive interspecies interactions, we hypothesize that different habitats within ecosystems can facilitate each other through structural complementarity and through exchange of material and energy across habitats. We show that experimental ecosystems comprised of a diversity of habitats show higher levels of multiple ecosystem functions than ecosystems with low habitat diversity. Our results demonstrate that the effect of habitat diversity on multifunctionality varies with season; it has direct effects on ecosystem functioning in summer and indirect effects, via changes in species diversity, in autumn, but no effect in spring. We propose that joint consideration of habitat diversity and species diversity will prove valuable for both environmental management and basic research.
Transposon Mutagenesis of the Plant-Associated Bacillus amyloliquefaciens ssp. plantarum FZB42 Revealed That the nfrA and RBAM17410 Genes Are Involved in Plant-Microbe-Interactions

Bacillus amyloliquefaciens ssp. plantarum FZB42 represents the prototype of Gram-positive plant growth promoting and biocontrol bacteria. In this study, we applied transposon mutagenesis to generate a transposon library, which was screened for genes involved in multicellular behavior and biofilm formation on roots as a prerequisite of plant growth promoting activity. Transposon insertion sites were determined by rescue-cloning followed by DNA sequencing. As in B. subtilis, the global transcriptional regulator DegU was identified as an activator of genes necessary for swarming and biofilm formation, and the DegU-mutant of FZB42 was found impaired in efficient root colonization. Direct screening of 3,000 transposon insertion mutants for plant-growth-promotion revealed the gene products of nfrA and RBAM_017140 to be essential for beneficial effects exerted by FZB42 on plants. We analyzed the performance of GFP-labeled wild-type and transposon mutants in the colonization of lettuce roots using confocal laser scanning microscopy. While the wild-type strain heavily colonized root surfaces, the nfrA mutant did not colonize lettuce roots, although it was not impaired in growth in laboratory cultures, biofilm formation and swarming motility on agar plates. The RBAM17410 gene, occurring in only a few members of the B. subtilis species complex, was directly involved in plant growth promotion. None of the mutant strains were affected in producing the plant growth hormone auxin. We hypothesize that the nfrA gene product is essential for overcoming the stress caused by plant response towards bacterial root colonization.
Intraoperative and Postoperative Gamma Detection of Somatostatin Receptors in Bone-invasive en Plaque Meningiomas

OBJECTIVE: Scintigraphy with a radiolabeled somatostatin analog (111In-diethylenetriaminepenta-acetic acid octreotide) detects the somatostatin receptors that are found in vitro in all meningiomas. Previous studies have proved the benefit of radioimmunoguided surgery, with a hand-held gamma probe, for the assessment and removal of neuroendocrine tumors. We conducted a study to determine whether intraoperative radiodetection of somatostatin receptors is feasible and could increase the probability of complete meningioma resection, especially for bone-invasive en plaque meningiomas, which are difficult to control surgically. METHODS Eighteen patients with en plaque sphenoid wing and cranial convexity meningiomas were studied by preoperative and postoperative somatostatin receptor scintigraphy. In 10 of them, intraoperative radiodetection with a hand-held gamma probe was performed 24 hours after the intravenous administration of 111In-diethylenetriaminepenta-acetic acid octreotide. This procedure was combined with a computer-aided navigation system. RESULTS: All preoperative scintigrams were positive. Intraoperative gamma probe detection was achieved for the invaded bone, dura, and periorbit of sphenoid wing meningiomas. The average tumor/nontumor count ratio was 2:1, with a maximum of 12:1, thus allowing precise detection capable of defining the tumor margins. In three cases of sphenoid wing meningiomas, postoperative scintigrams were helpful for the determination of recurrences that magnetic resonance imaging failed to detect. CONCLUSION: These preliminary data show that intraoperative radiodetection of somatostatin receptors with a hand-held gamma probe is feasible and may be helpful to guide the surgical removal of bone-invasive en plaque meningiomas. Preoperative and postoperative scintigraphy may be useful for the management and follow-up of patients with these tumors.
Chromosome Variation, Genomics, Speciation and Evolution in Sceloporus Lizards

The clade of the North American lizard genus Sceloporus and its relatives comprising the subfamily Phrynosomatinae (Iguanidae) includes perhaps 150 evolutionary lineages. The work reviewed here begins with the discovery of the concentration of Robertsonian chromosomal variability in Sceloporus more than 40 years ago and cytogenetic and genomic evidence of remarkable chromosomal variation within the S. grammicus complex associated with narrow zones of hybridization between different chromosomal races. These discoveries led to hypotheses about hybrid zones involving negative heterosis, possible modes of chromosomal speciation, and the potential roles of such speciation in phylogenesis. The radiation of Sceloporus has now been studied by many different workers extending and mapping the geographic distribution of cytogenetic and genomic variation to understand the biology of the chromosomal variation and to establish the phyletic relationships of the various lineages. The result is a robust phylogeny and a large and still growing database of genic, cytogenetic and other biological parameters. These materials provide a rich series of natural experiments to support both synthetic-comparative and analytical studies of the roles of chromosomal variation, hybrid zones and modes of speciation in phylogenesis and evolutionary success.
The Physical Conditions and Dynamics of the Interstellar Medium in the Nucleus of M83: Observations of CO and C I

This paper presents [C I],12CO J = 4-3, and 12CO J = 3-2 maps of the barred spiral galaxy M83 taken at the James Clerk Maxwell Telescope. Observations indicate a double-peaked structure, which is consistent with gas inflow along the bar collecting at the inner Lindblad resonance. This structure suggests that nuclear starbursts can occur even in galaxies where this inflow/collection occurs, in contrast to previous studies of barred spiral galaxies. However, the observations also suggest that the double-peaked emission may be the result of a rotating molecular ring oriented nearly perpendicular to the main disk of the galaxy. The 12CO J = 4-3 data indicate the presence of warm gas in the nucleus that is not apparent in the lower J CO observations, which suggests that 12CO J = 1-0 emission may not be a reliable tracer of molecular gas in starburst galaxies. The 12 [C I]/12CO J = 4-3 line ratios in the inner 24'' × 24'' are uniform at the 2 σ level, which indicates that the 12CO J = 4-3 emission is originating in the same hot photon-dominated regions as the [C I] emission. The 12CO J = 4-3/J = 3-2 line ratios vary significantly within the nucleus, with the higher line ratios occurring away from peaks of emission along an arc of active star-forming regions. These high line ratios (>1) likely indicate optically thin gas created by the high temperatures caused by star-forming regions in the nucleus of this starburst galaxy.
Dynamic Power Allocation Under Arbitrary Varying Channels - The Multi-User Case

We consider the power control problem in a time-slotted wireless channel, shared by a finite number of mobiles that transmit to a common base station. The channel between each mobile and the base station is time varying, and the system objective is to maximize the overall data throughput. It is assumed that each transmitter has a limited power budget, to be sequentially divided during the lifetime of the battery. We deviate from the classic work in this area, by considering a realistic scenario where the channel quality of each mobile changes arbitrarily from one transmission to the other. Assuming first that each mobile is aware of the channel quality of all other mobiles, we propose an online power-allocation algorithm, and prove its optimality under mild assumptions. We then indicate how to implement the algorithm when only local state information is available, requiring minimal communication overhead. Notably, the competitive ratio of our algorithm (nearly) matches the one we previously obtained for the (much simpler) single-transmitter case [BLMNO09], albeit requiring significantly different algorithmic solutions.
Risk factors for femicide in abusive relationships: results from a multisite case control study.

OBJECTIVES This 11-city study sought to identify risk factors for femicide in abusive relationships. METHODS Proxies of 220 intimate partner femicide victims identified from police or medical examiner records were interviewed, along with 343 abused control women. RESULTS Preincident risk factors associated in multivariate analyses with increased risk of intimate partner femicide included perpetrator's access to a gun and previous threat with a weapon, perpetrator's stepchild in the home, and estrangement, especially from a controlling partner. Never living together and prior domestic violence arrest were associated with lowered risks. Significant incident factors included the victim having left for another partner and the perpetrator's use of a gun. Other significant bivariate-level risks included stalking, forced sex, and abuse during pregnancy. CONCLUSIONS There are identifiable risk factors for intimate partner femicides.
Tensile mechanics of braided sutures

Sutures are the materials primarily used for closing wounds, and their performance is significantly dependent on their mechanical characteristics. Thus, their tensile property is a key parameter responsible for the success of a suture. In this paper, a simple analytical tensile model of braided sutures has been developed based on braid geometry, braid kinematics, and constituent monofilament properties. The model has accounted for the changes in the braid geometry, including braid angle, diameter, and Poisson’s ratio. The kinematics of the braided suture is analyzed pertaining to monofilament locking or jamming in the braid. The model of jamming state of monofilaments has been presented, and both braid angle and diameter are found to be critical design parameters. The experimental results have been compared to the theoretical stress–strain curves of braided sutures, and an excellent agreement has been observed between them.