Miracle-dz/UniFAR-FTUs huggingface dataset:
Made in the (Multicultural) U.S.A.: Unpacking Tensions of Race, Culture, Gender, and Sexuality in Education

The author discusses the challenges of educating teachers to engage, rather than deny or repress, differences that emerge at the dynamic, context-specific intersections of race, culture, gender, and sexuality. Although multicultural education discourse is well established, stereotypic representations and repressive silences persist in the sphere of practice. Interweaving postcolonial and feminist theories with reflections emerging from her multicultural teacher education practice, the author highlights tensions of doing multicultural work. She discusses how silencing forces operate even in seemingly “open” micro and macro contexts. To illustrate these arguments, the author engages two areas that have received limited attention in multicultural discourse itself: representations of Asian Americans and differences of sexuality. She recommends that the multicultural teacher education classroom serve as a site for modeling critical, self-reflexive engagement with difference and democratic participation, even as she acknowledges the limits of individual efforts in the process of educational and social change.
Evidence and liberty

Evidence and liberty are two great ideas in British history. One consequence of both ideas is experimental criminology, which applies research designs developed in Britain to matters of liberty affecting the entire world. The promise of experimental criminology is to generate better evidence about how to increase liberty. The crucial challenge to experimental criminology is the means by which research results, even when accepted as true, may be translated into widespread practice. Two models for applying experimental research are possible. One is `bottom—up discretion', in which crime victims, police, judges and probation officers and others take experimental results into account when making their decisions one case at a time. Another model is `top—down guidance', in which either Ministers or an independent evidence-assessment agency like `NICE'—the National Institute of Health and Clinical Excellence—appoint committees of practitioners and researchers to develop succinct operational guidance based upon systematic reviews of experimental evidence. Bottom—up discretion will grow steadily from the sheer persistence of criminologists and practitioners doing experiments. Liberty could be advanced much faster by top—down guidance, however, if government chose to invest in `prospective meta-analysis' a method of multi-site randomized trials that would assess generalizability of policy effects as well as their magnitude and cost-effectiveness.
Conditional effects of interventions in note‐taking procedures on learning: A meta‐analysis

Abstract: A meta-analysis was conducted on 17 studies (27 separate samples and 73 effect sizes) examining the effects of interventions in the note-taking procedures on learning from lectures or texts. The overall mean weighted effect size (d) for the intervention groups versus the no intervention groups was 0.02. To explore what factors influence the intervention effects, moderator analyses were conducted separately for intervention type, schooling level, presentation method, publication source, and publication year. The results indicated that students at a lower schooling level gained some benefits from the interventions, whereas students at a higher schooling level did not. Also, the intervention effects were greater for journal articles than for doctoral dissertations and Education Resources Information Center reports. Other variables did not significantly account for the variance in effect sizes.
Vinculin Regulates Osteoclast Function*

Background: Vinculin, an actin-binding protein, is essential for cytoskeletal organization. Results: Vinculin deficiency in osteoclasts impairs osteoclast function, not differentiation, leading to increased bone mass in vivo. Conclusion: Vinculin expression regulates osteoclast function in a talin-dependent, αvβ3 integrin-independent manner. Significance: This is the first demonstration that vinculin regulates osteoclast function. Osteoclastic bone resorption depends upon the cell's ability to organize its cytoskeleton. Because vinculin (VCL) is an actin-binding protein, we asked whether it participates in skeletal degradation. Thus, we mated VCLfl/fl mice with those expressing cathepsin K-Cre (CtsK-VCL) to delete the gene in mature osteoclasts or lysozyme M-Cre (LysM-VCL) to target all osteoclast lineage cells. VCL-deficient osteoclasts differentiate normally but, reflecting cytoskeletal disorganization, form small actin rings and fail to effectively resorb bone. In keeping with inhibited resorptive function, CtsK-VCL and LysM-VCL mice exhibit a doubling of bone mass. Despite cytoskeletal disorganization, the capacity of VCL−/− osteoclastic cells to normally phosphorylate c-Src in response to αvβ3 integrin ligand is intact. Thus, integrin-activated signals are unrelated to the means by which VCL organizes the osteoclast cytoskeleton. WT VCL completely rescues actin ring formation and bone resorption, as does VCLP878A, which is incapable of interacting with Arp2/3. As expected, deletion of the VCL tail domain (VCL1–880), which binds actin, does not normalize VCL−/− osteoclasts. The same is true regarding VCLI997A, which also prevents VCL/actin binding, and VCLA50I and VCL811–1066, both of which arrest talin association. Thus, VCL binding talin, but not Arp2/3, is critical for osteoclast function, and its selective inhibition retards physiological bone loss.
Towards a Gendered Skills Analysis of Senior Management Positions in UK and Australian Universities

Women remain outsiders in university leadership and management. The literature indicates that discipline base, career mobility, experience outside academia, selection processes, and gender stereotyping may impact on women becoming senior managers. This article reports on research with current and former Vice‐Chancellors, senior managers, and recruitment firms to identify skill requirements for effective leadership and management. Our research indicates gender is an issue in higher education leadership, in recruitment and selection, exclusion from male camaraderie, and preference for transformational leadership. This research will produce a skills benchmark to assess future leadership positions and hopefully cut across current gender bias.
Work satisfaction and the ESL profession

Abstract This paper reviews the topic of work satisfaction with particular reference to the ESL field. An overview of the literature indicates that work satisfaction is a complex response which incorporates many influences inside and outside of the work environment. The available survey data, primarily from members of the TESOL organisation, suggest that ESL practitioners are basically satisfied with their work, though they experience dissatisfactions in certain areas such as promotions, pay, and some administrative aspects. It is maintained that the key to ensuring work satisfaction and the positive career conditions which educators in ESL desire and deserve is professional recognition.
Enumerating β-Cells in Whole Human Islets: Sex Differences and Associations With Clinical Outcomes After Islet Transplantation

Islet transplantation is an experimental therapy for type 1 diabetes. Though it is increasingly successful, limitations include unpredictable declines in islet graft function (1). There is still inadequate knowledge of specific human islet characteristics that predispose to successful and durable islet graft function and what types of donors are more likely to have islets with these beneficial traits. The relationship between the composition of dissociated human islets (as opposed to whole islets) and transplant outcomes has been studied (2), with a positive association between recipients’ acute insulin response to glucose (AIRg) posttransplant and number of pancreatic ductal cells in the preparation (a positive association with number of β-cells approached significance). However, as dissociation inherently damages islets, β-cells enumerated after dissociation may no longer reflect the number of β-cells within whole islets ultimately transplanted. Using an epidemiological approach, we therefore investigated 1 ) the independent association of the β-cell composition of transplanted whole human islets with recipient outcomes and 2 ) the donor …
Evaluation of different Diagnostic Modalities for Diagnosis of Dental Caries: An in vivo Study

Aim The aim of this study was to compare and evaluate the efficacy of different diagnostic aids for diagnosis of dental caries and to compare the validity in terms of sensitivity and specificity of all four diagnostic modalities for diagnosis of caries. Materials and methods Occlusal surfaces of 100 primary and permanent molars were examined using the four diagnostic systems (visual, intraoral camera, DIAGNOdent, and DIAGNOdent with dye). These results were compared with operative intervention gold standard. Sensitivity and specificity were calculated for each diagnostic system for both enamel and dentin caries. Interrater agreement was calculated for each diagnostic system using kappa statistics. Results For both enamel and dentin caries, the highest sensitivity values were provided by DIAGNOdent (0.91 and 0.72) and lowest for visual examination on wet surface (0.60 and 0.50). For both enamel and dentin caries, the specificity was found to be highest for intraoral camera on dry surface and lowest for visual examination. The DIAGNOdent gave the highest value of interrater agreement (kappa), i.e., 0.816 as compared with 0.03 for visual examination. Conclusion The study clearly demonstrated that DIAGNO-dent was the most accurate and valid system tested for the detection of occlusal caries. It has the advantage of quantifying the mineral content, helping to improve the diagnostic efficacy and treatment and accurate assessment of fissures where the visual examination alone is not adequate, thus complementing the traditional dental examination. How to cite this article Zaidi I, Somani R, Jaidka S, Nishad M, Singh S, Tomar D. Evaluation of different Diagnostic Modalities for Diagnosis of Dental Caries: An in vivo Study. Int J Clin Pediatr Dent 2016;9(4):320-325.
Effet de la maladie de Parkinson et de la médication dopaminergique sur les mécanismes de traitement et d'intégration sensorielle et l'adaptation visuomotrice

The integrity of our sensorimotor system is essential for adequate interactions with the environment. In Parkinson’s disease (PD), the efficiency of the daily interactions between the body and the environment is often reduced and interfere with quality of life. PD is a neurodegenerative disease resulting primarily from a dopaminergic neuronal loss in the basal ganglia (BG). This progressive loss of neurons alters the normal functioning of the BG-cortical circuitry. Dopaminergic medication is well known to remediate the major clinical motor symptoms of PD. This thesis investigates the role of the BG in the processing and integration of visual and proprioceptive sensory information and in visuomotor adaptation. This thesis also explores the influence of dopaminergic medication on these sensorimotor functions. We performed three behavioral studies using three-dimensional reaching movements as an experimental model. In each study, we compared the performance of healthy controls and individuals suffering from PD, while in the non-medicated condition and when on their regular daily antiparkinsonian medication. These three studies were performed using a movement analysis system and a virtual reality station. In the first study, we evaluated whether the BG are primarily involved in sensorimotor integration or in the processing of proprioceptive sensory information. We tested the ability of PD patients to perform accurate reaching movements in four conditions in which the sensory signals defining target and hand positions (vision and/or proprioception) varied. On average, PD patients made larger spatial errors than healthy controls when proprioception was the only source of sensory information available. Furthermore, these movement inaccuracies were significantly larger than those of healthy controls only when PD patients where tested in the medicated condition. The second study presented in this thesis demonstrated that the greater movement inaccuracies of PD patients in the proprioceptive conditions resulted mainly from impaired use of proprioceptive information for on-line movement guidance.
Language Identification in Mixed Script

The text exchanged in social media conversations is often noisy with a mixture of stylistic and misspelt variations of original words. Any standard NLP techniques applied on such data such as POS tagging, Named entity recognition suffer because of noisy nature of the input. Usage of mixed script text is also prevalent in social media users. The current work addresses the identification of language at word level in mixed script scenarios, where all the text is written in roman script but the words being used by the users are transliterations of original words in native language into english. The core part of the problem is identifying the language, looking at small fragments of text among a set of languages. We propose a two stage approach for word-level language identification. In the first stage a mixing language combination is identified by using character n-grams of the sentence. Second stage consists of using the previous mixing combination class to make the word level language identification. We apply Conditional Random Fields(CRF) further in second stage to improve the performance of the word level language identification. Such simplification is essential, otherwise the number of states of the model will be huge and resultant model predictions are very noisy. Our methods improve the F-score of word level language identification by over 10% compared to the base-line.
Each Member of the Poly-r(C)-binding Protein 1 (PCBP) Family Exhibits Iron Chaperone Activity toward Ferritin*

Background: Some iron-dependent enzymes acquire their cofactor from iron chaperones, such as PCBP1. Results: PCBP2, and PCBP3 interact with iron and ferritin in yeast and human cells. Conclusion: All PCBP family members may function as iron chaperones. Significance: The PCBP family members are multifunctional adaptors, mediating interactions between iron or nucleic acids and proteins that act on these molecules. The mechanisms through which iron-dependent enzymes receive their metal cofactors are largely unknown. Poly r(C)-binding protein 1 (PCBP1) is an iron chaperone for ferritin; both PCBP1 and its paralog PCBP2 are required for iron delivery to the prolyl hydroxylase that regulates HIF1. Here we show that PCBP2 is also an iron chaperone for ferritin. Co-expression of PCBP2 and human ferritins in yeast activated the iron deficiency response and increased iron deposition into ferritin. Depletion of PCBP2 in Huh7 cells diminished iron incorporation into ferritin. Both PCBP1 and PCBP2 were co-immunoprecipitated with ferritin in HEK293 cells, and expression of both PCBPs was required for ferritin complex formation in cells. PCBP1 and -2 exhibited high affinity binding to ferritin in vitro. Mammalian genomes encode 4 PCBPs, including the minimally expressed PCBPs 3 and 4. Expression of PCBP3 and -4 in yeast activated the iron deficiency response, but only PCBP3 exhibited strong interactions with ferritin. Expression of PCBP1 and ferritin in an iron-sensitive, ccc1 yeast strain intensified the toxic effects of iron, whereas expression of PCBP4 protected the cells from iron toxicity. Thus, PCBP1 and -2 form a complex for iron delivery to ferritin, and all PCBPs may share iron chaperone activity.
Characterization of cross-line up to 110 GHz using two-port measurements

Cross-line, a four-port device, used for capacitive cross coupling in differential millimeter-wave amplifiers is modeled and characterized up to 110 GHz using two-port vector network analyzer measurement results. This passive component is electrically symmetrical to be used in differential amplifiers for decreased amplitude and phase mismatch. Two characterization structures are used for the method to be applied. The results are compared with four-port measurements up to 67 GHz. The comparisons show good agreement between the two methods.
Listening to the children: Interviews with children attending a mainstream support facility

Geraldine Tisdall and Ron Dawson have investigated the attitudes and opinions of twenty-one students attending a support facility for those with physical disability or hearing impairment in a large comprehensive school. The students obviously welcomed the opportunity to do this and expressed themselves lucidly and forcibly. While some general conclusions can be drawn from this study, the most significant factor that emerges is the unique individuality of the respondents in their own right.
Life Decisions of Taiwanese Women Who Care for a Sibling With Cerebral Palsy

We used a phenomenological method to examine how the caregiving experiences of Taiwanese women who care for a sibling with cerebral palsy (CP) influence their life decisions. In-depth qualitative interviews were conducted with six adult women, each of whom self-identified as being the sister most involved in caring for a sibling with CP. Themes emerging from caregivers’ experiences were caring through interpretation, caring through protection, and caring through sacrifice. These ways of caring created unique considerations and tensions that appeared to have a profound effect on the women's major life decisions.
Blood glucose responses to reductions in pre-exercise rapid-acting insulin for 24 h after running in individuals with type 1 diabetes

Abstract In this study, we examined pre-exercise insulin reductions on consequent metabolic and dietary patterns for 24 h after running in individuals with type 1 diabetes. Seven participants self-administered their Full rapid-acting insulin dose or 75%, 50% or 25% of it, immediately before consuming a 1.12-MJ meal. After 2 h, participants completed 45 min of running at 70% peak oxygen uptake ([Vdot]O2peak). Blood glucose and insulin were measured for 2 h before and 3 h after exercise. Blood glucose, diet, and administered insulin were self-recorded for 24 h after exercise. Data were analysed using repeated-measures analysis of variance. Pre-exercise peak insulin concentrations were greatest with the Full dose and consequently elicited the lowest blood glucose concentrations (P < 0.05). Blood glucose decreased under all conditions with exercise, with the fall with the Full dose (−6.1 mmol · l−1, sx = 0.4) greater than with 25% insulin (−3.2 mmol · l−1, sx = 0.4; P < 0.05). There was little change in blood glucose from 0 to 3 h post-exercise under all conditions (P > 0.05). Blood glucose at 3 h post-exercise was greatest with the 25% dose. Over the next 21 h, blood glucose area under the curve was greater with the 25% dose compared with all other trials despite consuming less energy and fewer carbohydrates (P < 0.05). A 75% reduction to pre-exercise insulin results in the greatest preservation of blood glucose, and a reduced dietary intake, for 24 h after running in individuals with type 1 diabetes.
Behavioral and Psychological Symptoms of Dementia and Caregiver Burden

Most patients with Alzheimer's disease (AD) are cared for in their own homes. The costs of this care can be documented in several different ways—financial, time spent in the caregiving role, and strain or burden on the caregiver. This strain and burden on caregivers can manifest in a variety of ways, including increased use of prescribed medication and more primary care visits (Haley, 1997). Vulnerability to strain is heightened by a previous history of psychiatric disorder in the caregiver (Baumgarten et al., 1992; Hooker, 1992). Depression is a particularly common accompaniment to the caregiving role, affecting between 25% and 70% of caregivers (Dura et al., 1990; Teri, 1994). Physical manifestations of caregiving burden include impaired immune function, elevated blood pressure, abnormal plasma lipid levels, and poor self-care (e.g., sleeplessness and lack of exercise) (Haley, 1997).
Maternal Dysphoric Mood, Stress, and Parenting Practices in Mothers of Head Start Preschoolers: The Role of Experiential Avoidance

Maternal dysphoria predicts behavioral difficulties in preschool-aged children, and may contribute to negative child outcomes by exacerbating parenting stress. Parenting stress increases the likelihood of maladaptive parenting practices, especially when mothers face multiple contextual stressors. We explored maternal experiential avoidance (EA) as mechanism through which dysphoria amplifies parenting stress. One hundred and forty-four diverse, low-income mothers of Head Start preschoolers participated. Dysphoria, parenting stress, child behavior problems, and maladaptive parenting were positively correlated with EA. Further, EA mediated the relationship between dysphoria and parenting stress. Finally, parenting stress was uniquely predictive of inconsistent and punitive parenting practices.
Leadership and Organizational Tenure Diversity as Determinants of Project Team Effectiveness

The present study reveals how leadership effectiveness in project teams is dependent on the level of organizational tenure diversity. Data from 34 project teams showed that transformational leadership is related to organizational commitment, creative behavior, and job satisfaction, but only in teams with high organizational tenure diversity. By contrast, participative leadership has no impact on team innovativeness, team performance, and team conflict in teams with high organizational tenure diversity, yet is beneficial with respect to the same outcomes in teams that are low in organizational tenure diversity. Theoretical and practical implications for leading project teams and future research in this area are discussed.
The Researcher's Own Therapy Allegiances: A "Wild Card" in Comparisons of Treatment Efficacy

This report examines a possible distortion in the results of comparative treatment studies due to the association of the researcher's treatment allegiances with outcomes of those treatments. In eight past reviews a trend appeared for significant associations between the researcher's allegiance and outcomes of treatments compared. In a new review of 29 studies of treatment comparisons, a similar trend appeared. Allegiance ratings were based not only on the usual reprint method, but also on two new methods: ratings by colleagues who knew the researcher well, and self-ratings by the researchers themselves. The two new allegiance methods Interco related only moderately, but each allegiance measure correlated significantly with outcomes of the treatments compared, and when combined, the three measures explained 69% of the variance in outcomes Such an association can distort comparative treatment results. Our report concludes with how the researcher's allegiance may become associated with treatment outcomes and how studies should deal with these associations.