Miracle-dz/UniFAR-FTUs huggingface dataset:
Amharic Infixing Reduplication Targets Heavy Syllables

UC Berkeley Phonology Lab Annual Report (2014) Amharic infixing reduplication targets heavy syllables Hannah Sande January 2, 2015 Introduction Amharic, a Semitic language spoken in Ethiopia, has a crosslinguistically unique infixing reduplication pattern. The plural marker on adjectives and the iterative marker on verbs are reduplicative infixes which target heavy syllables. This means these infixes can only surface in words containing heavy syllables. Adjectives without heavy syllables must find an alternative way to express plural agreement with a plural head noun, and iterative phrases containing a verb without a heavy syllable must find an alternative means of expressing iterativity. Here I describe the infixing reduplication system in Amharic and demonstrate that the target of infixation in Amharic further illuminates the typology of infix- ation pivots as presented by Yu (2007, 2003). Yu claims that infixes target linear, segmental, or prosodic positions that every word is likely to have, specifically word edges, and prominent positions (Yu 2003:193). Yu proposes two competing pres- sures determining infix location the edge and prominent infix positions we see crosslinguistically. First, the Salient Pivot Hypothesis (Yu 2007:9) states that phonological infixes target psycholinguistically or phonetically salient positions. Second is the idea that infix sites are more reliable if more words possess that site (Yu 2003:195). These two pressures work together to ensure that infixes surface in salient positions present in most words. Amharic reduplication targets not an edge or the most prominent position in a word; it targets heavy syllables, which are not present in every word. Thus, based on the data presented throughout this paper I propose a constraint-based account of reduplicative infixation in Amharic (Prince, 1995), and I posit a modification to Yu (2007)’s list of possible infixation targets. Amharic is spoken by 21,600,000 people in Ethiopia and another 200,000 out- side of Ethiopia. Unless otherwise specified, the data presented in this paper comes from original work with two native speakers of Amharic from September
Renal expression of angiotensin receptors in long-term diabetes and the effects of angiotensin type 1 receptor blockade

Objective The aims of this study were to assess the renal expression of angiotensin type 1 (AT1) and type 2 (AT2) receptors in diabetic spontaneously hypertensive rats (SHR) and the effect of AT1 receptor blockade on the expression of these receptors. Design Diabetes was induced by injection of streptozotocin in SHRs. Irbesartan, an AT1 receptor antagonist, was given to diabetic SHRs for 32 weeks (15 mg/kg per day, n = 10). Diabetic (n = 10) and non-diabetic SHRs (n = 10) were studied concurrently. A separate group of control and diabetic Wistar–Kyoto (WKY) rats were also evaluated. Methods Gene and protein expressions of the AT1 and AT2 receptor were assessed by reverse transcription-polymerase chain reaction (RT-PCR), immunohistochemistry with specific antibodies and in vitro autoradiography with [125I]Sar(1), Ile(8) angiotensin II or [125I]CGP42112B. Results Both AT1 and AT2 receptor mRNA levels in the kidney were reduced in diabetic SHRs compared to non-diabetic SHRs. Immunohistochemistry staining with specific antibodies showed a similar reduction in glomerular and tubulo-interstitial staining for both AT1 and AT2 receptors. Reduced binding for the AT1 and AT2 receptor was found in the kidney of diabetic SHRs. Diabetic SHRs developed albuminuria and had glomerular and tubulo-interstitial injury, which were prevented by treatment with irbesartan. Reduced expression of the AT1 receptor, but not the AT2 receptor, in diabetic SHRs was prevented by treatment with irbesartan. In diabetic WKY rats no such reduction in AT1 expression was observed, although there was a trend for reduced AT2 receptor expression. Conclusions These findings demonstrated that renal expression of both AT1 and AT2 receptor was reduced in long-term diabetic SHRs and that blockade of the AT1 receptor had disparate effects on expression of angiotensin II receptor subtypes.
MAC Layer Throughput Estimation in Impulse-Radio UWB Networks

The inherent channel characteristics of impulse-based UWB networks affect the MAC layer performance significantly. Most previous studies on evaluating MAC protocols are based on prolonged simulations and do not account for the multiple access interference due to multipath delay spread. In this work, we develop CTU, an analytical framework for Capturing the Throughput dependencies in UWB networks, while taking into account the PHY layer effects. The key attributes of CTU are: 1) It is modular; it can be easily modified to provide a basis for evaluating a wide range of MAC protocols for impulse-based UWB networks. The only requirements are that the MAC protocol under study be based on time-hopping and the modulation scheme be pulse position modulation; these are common design decisions in UWB networks. 2) It considers the channel characteristics in addition to MAC layer effects; CTU correlates probabilistically the multipath delay profile of the channel with the packet error rate. We employ CTU to evaluate the performance of different generic medium access procedure. We compare the results with those from extensive simulations and show the high accuracy of CTU. We use CTU to assess the impact of various system parameters on the MAC layer performance; we make several interesting observations that are discussed in depth.
Apprehensions of Substitute Teachers

S ubstitute teachers are in a class by themselves. Sometimes accused of lacking commitment and working "purely for the money," they are nevertheless expected to provide continuity in a classroom on a few moments' notice and are a desperately needed resource in public and private school systems (Meickle 1986). The substitute teacher is perhaps one of the most maligned educators in today's schools. Even the title "substitute" seems to denote a teacher who is somehow less than a regular teacher. Students seem to have little respect for them, regular teachers look upon them as a necessary evil, and administrators sometimes ignore them completely. Yet the expectations of substitutes-to teach a class they are not prepared for, to maintain order and discipline in a classroom of students they have never seen before, and to operate in an environment foreign to them-are perhaps greater than the expectations for regular teachers. Although reports vary, it is estimated that students will have seven to ten of their total classroom dayseach year supervised by a substitute teacher (Kraft 1980; Drake 1981). This amount may be increasing as teacher contracts provide more personal, professional, and sick leave. Substitute teachers, however, are not receiving additional attention. In 1970, Stevens reported that the typical substitute teacher program had maintained its "antiquated status" despite innovations in other areas. This situation has changed little. Literature that can be found relating to substitute teaching usually prescribes how to leave better plans for a substitute; there is little material available on substitute teachers. Many questions need to be answered. Who are these substitute teachers? What are their reasons for becoming substitutes? What are their apprehensions about their chosen role as a substitute teacher? What efforts by administrators and teachers can alleviate their apprehensions? The purpose of this article is to report a recent study of the apprehensions of substitute teachers related to their role as substitutes. This information may help inform teachers and administrators about the concerns of substitutes and enable them to alleviate those concerns where possible.
Supervised and unsupervised methods for prostate cancer segmentation with multispectral MRI.

PURPOSE Magnetic resonance imaging (MRI) has been proposed as a promising alternative to transrectal ultrasound for the detection and localization of prostate cancer and fusing the information from multispectral MR images is currently an active research area. In this study, the goal is to develop automated methods that combine the pharmacokinetic parameters derived from dynamic contrast enhanced (DCE) MRI with quantitative T2 MRI and diffusion weighted imaging (DWI) in contrast to most of the studies which were performed with human readers. The main advantages of the automated methods are that the observer variability is removed and easily reproducible results can be efficiently obtained when the methods are applied to a test data. The goal is also to compare the performance of automated supervised and unsupervised methods for prostate cancer localization with multispectral MRI. METHODS The authors use multispectral MRI data from 20 patients with biopsy-confirmed prostate cancer patients, and the image set consists of parameters derived from T2, DWI, and DCE-MRI. The authors utilize large margin classifiers for prostate cancer segmentation and compare them to an unsupervised method the authors have previously developed. The authors also develop thresholding schemes to tune support vector machines (SVMs) and their probabilistic counterparts, relevance vector machines (RVMs), for an improved performance with respect to a selected criterion. Moreover, the authors apply a thresholding method to make the unsupervised fuzzy Markov random fields method fully automatic. RESULTS The authors have developed a supervised machine learning method that performs better than the previously developed unsupervised method and, additionally, have found that there is no significant difference between the SVM and RVM segmentation results. The results also show that the proposed methods for threshold selection can be used to tune the automated segmentation methods to optimize results for certain criteria such as accuracy or sensitivity. The test results of the automated algorithms indicate that using multispectral MRI improves prostate cancer segmentation performance when compared to single MR images, a result similar to the human reader studies that were performed before. CONCLUSIONS The automated methods presented here can help diagnose and detect prostate cancer, and improve segmentation results. For that purpose, multispectral MRI provides better information about cancer and normal regions in the prostate when compared to methods that use single MRI techniques; thus, the different MRI measurements provide complementary information in the automated methods. Moreover, the use of supervised algorithms in such automated methods remain a good alternative to the use of unsupervised algorithms.
Connecting Self-Awareness and Error-Awareness in Patients with Traumatic Brain Injury

Abstract Impaired self-awareness after traumatic brain injury (TBI) is often seen in stark contrast to the observations of significant-others, who are acutely aware of the difficulties experienced by patients. Our objective was to investigate the relationship between metacognitive knowledge in daily life and emergent awareness of errors during laboratory tasks, since the breakdown of error detection mechanisms may impose limitations on the recovery of metacognitive knowledge after TBI. We also examined the extent to which these measures of awareness can predict dysexecutive behaviors. A sample of TBI patients (n=62) and their significant-others, provided reports of daily functioning post injury. In addition, patients underwent a neuropsychological assessment and were instructed to signal their errors during go/no-go tests. Interrelationships between metacognitive and emergent levels of awareness were examined, after controlling for the influence of secondary cognitive variables. Significant-other ratings correlated with errors made by the patients on neuropsychological tests but not with their premorbid function. Patients who under-reported daily life difficulties or over-reported their competency, compared to significant-other reports, were less likely to show awareness of laboratory errors. Emergent awareness was also identified as the sole predictor of performance on the modified six-element test, an ecologically valid test of multitasking. The online breakdown of error awareness after brain injury is related to difficulties with metacognitive awareness as reported in daily life, and is also predictive of dysexecutive behaviors. These findings are discussed in the context of multidimensional and neural models of awareness and error monitoring. (JINS, 2015, 21, 473–482)
Evolution of Courtship Songs in Xenopus: Vocal Pattern Generation and Sound Production

The extant species of African clawed frogs (Xenopus and Silurana) provide an opportunity to link the evolution of vocal characters to changes in the responsible cellular and molecular mechanisms. In this review, we integrate several robust lines of research: evolutionary trajectories of Xenopus vocalizations, cellular and circuit-level mechanisms of vocalization in selected Xenopus model species, and Xenopus evolutionary history and speciation mechanisms. Integrating recent findings allows us to generate and test specific hypotheses about the evolution of Xenopus vocal circuits. We propose that reduced vocal sex differences in some Xenopus species result from species-specific losses of sexually differentiated neural and neuromuscular features. Modification of sex-hormone-regulated developmental mechanisms is a strong candidate mechanism for reduced vocal sex differences.
A prefrontal–temporal network underlying state changes between Stimulus-Driven and Stimulus-Independent Cognition

The brain displays moment-to-moment activity fluctuations that reflect various levels of engagement with the outside world. Processing external stimuli is not only associated with increased brain metabolism but also with prominent deactivation in specific structures, collectively known as the default-mode network (DMN). The role of the DMN remains enigmatic partly because its electrophysiological correlates and temporal dynamics are still poorly understood. Using unprecedented wide-spread depth recordings in epileptic patients, undergoing intracranial EEG during pre-surgical evaluation, we reveal that DMN neural populations display task-related suppressions of gamma (60-140 Hz) power and, critically, we show how millisecond temporal profile and amplitude of gamma deactivation tightly correlate with task demands and subject performance. The results show also that during an attentional task, sustained activations in the gamma band power are presented across large cortical networks, while transient activations are mostly specific to occipital and temporal regions. Our findings reveal a pivotal role for broadband gamma modulations in the interplay between activation and deactivation networks mediating efficient goal-directed behavior
E-learning Information Technology Based on an Ontology Driven Learning Engine

In the article, proposed is a new e-learning information technology based on an ontology driven learning engine, which is matched with modern pedagogical technologies. With the help of proposed engine and developed question database we have conducted an experiment, where students were tested. The developed ontology driven system of e-learning facilitates the creation of favorable conditions for the development of personal qualities and creation of a holistic understanding of the subject area among students throughout the educational process.
Cautioning Health-Care Professionals

Science and practice seem deeply stuck in the so-called stage theory of grief. Health-care professionals continue to “prescribe” stages. Basically, this perspective endorses the idea that bereaved people go through a set pattern of specific reactions over time following the death of a loved one. It has frequently been interpreted prescriptively, as a progression that bereaved persons must follow in order to adapt to loss. It is of paramount importance to assess stage theory, not least in view of the current status of the maladaptive “persistent complex bereavement-related disorder” as a category for further research in DSM-5. We therefore review the status and value of this approach. It has remained hugely influential among researchers as well as practitioners across recent decades, but there has also been forceful opposition. Major concerns include the absence of sound empirical evidence, conceptual clarity, or explanatory potential. It lacks practical utility for the design or allocation of treatment services, and it does not help identification of those at risk or with complications in the grieving process. Most disturbingly, the expectation that bereaved persons will, even should, go through stages of grieving can be harmful to those who do not. Following such lines of reasoning, we argue that stage theory should be discarded by all concerned (including bereaved persons themselves); at best, it should be relegated to the realms of history. There are alternative models that better represent grieving processes. We develop guidelines to enhance such a move beyond the stage approach in both theory and practice.
Routine operation theatre extubation after cardiac surgery in the elderly.

OBJECTIVES The aim was to analyse in-hospital outcomes of patients over 70 years of age undergoing routine immediate operation theatre (OT) extubation after on-pump or off-pump cardiac surgery. METHODS A retrospective analysis was performed of prospectively collected data over a 4-year period (2011-14) from elderly patients undergoing early extubation after cardiac surgery at a single institution. All patients over 70 years were considered eligible for immediate OT or intensive care unit (ICU) early extubation after meeting specific criteria. All types of non-emergency cardiac surgery were included. Cardiac surgical risk stratification was assessed with EuroSCORE II and age, creatinine level and left ventricular ejection fraction (ACEF) score. RESULTS Among the 415 patients operated on during the period, 275 (66.3%) were ≥70 years old. One hundred and forty patients (50.9%) of the elderly group were extubated successfully in the OT. Excluding off-pump coronary surgery, OT extubation was achieved in 51.5% of cases. The rate of risk of reintubation within 24 h of surgery after OT extubation was 2.1%. The in-hospital mortality rate was 4.7%, and the complication rate was 11.6%, independently of extubation timing. Elderly patients extubated in the OT had a significantly lower median EuroSCORE II risk level and ACEF score, more isolated valve surgeries, reduced cardiopulmonary bypass time, less complications and shorter length of stay than ICU-extubated patients. In the multivariate analysis, only the ACEF score remained as an independent variable associated with OT extubation in the elderly (odds ratio 25.0, 95% CI 2.74-228.8, P = 0.004), and had good discriminating power [receiver operating characteristics (ROC) area 0.713]. On the other hand, the EuroSCORE ROC area used to predict OT extubation was 0.694, and the cut-off analysis showed that a risk value under 2.11 was associated with 72.1% OT extubation versus 37.3% when the risk value was over 2.11 (P = 0.0002). CONCLUSIONS OT extubation in the elderly can be safely performed in nearly 50% of patients, without apparently worsening their outcomes. A key point of this success was the use of a short-acting volatile agent to maintain anaesthesia throughout the procedure. Low- or moderate-risk cardiac surgery assessed with a preoperative EuroSCORE II <2.11 will help to better predict successful OT extubation in the elderly.
The LupusQoL and Associations with Demographics and Clinical Measurements in Patients with Systemic Lupus Erythematosus

Objective. Having developed and validated a disease-specific health-related quality of life (HRQOL) measure for patients with systemic lupus erythematosus (SLE), the LupusQoL, we determined its relationship to demographic and clinical measurements in a group of patients with SLE. Methods. A group of 322 outpatients completed the LupusQoL. Demographic (age, sex, marital status, ethnicity) and clinical variables (disease duration, disease activity, damage) were recorded. Associations between the 8 LupusQoL domains and age, disease duration, disease activity, and damage were explored using Spearman’s correlation coefficients. Differences in LupusQoL scores were examined for sex and marital status using the Mann-Whitney U test. Ethnic groups were compared using ANOVA. Results. All domains of LupusQoL were impaired, with fatigue (56.3) being the worst affected and body image (80.0) the least. The correlations between the LupusQoL domain scores and age (r = −0.01 to −0.22) and disease duration (r = 0 to 0.16) were absent or weak. Similarly, there were no significant differences in the LupusQoL scores regarding sex, marital status, or the 3 main ethnic groups (Black-Caribbean, Asian, White). Although there were statistically significant correlations between the scores of the LupusQoL domains and some scores of the British Isles Lupus Assessment Group index (r = −0.22 to 0.09) and the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (r = −0.29 to 0.21), these were weak. Conclusion. HRQOL was impaired in this cohort of outpatients with SLE as assessed by the validated lupus-specific LupusQoL. There were no clinically important associations between the 8 domains of the LupusQoL and clinical or demographic variables in this group of patients. Thus, the LupusQoL is a relatively independent outcome measure in patients with SLE.
In Search of Prosperity: Analytic Narratives on Economic Growth

The economics of growth has come a long way since it regained center stage for economists in the mid-1980s. Here for the first time is a series of country studies guided by that research. The thirteen essays, by leading economists, shed light on some of the most important growth puzzles of our time. How did China grow so rapidly despite the absence of full-fledged private property rights? What happened in India after the early 1980s to more than double its growth rate? How did Botswana and Mauritius avoid the problems that other countries in sub - Saharan Africa succumbed to? How did Indonesia manage to grow over three decades despite weak institutions and distorted microeconomic policies and why did it suffer such a collapse after 1997? What emerges from this collective effort is a deeper understanding of the centrality of institutions. Economies that have performed well over the long term owe their success not to geography or trade, but to institutions that have generated market-oriented incentives, protected property rights, and enabled stability. However, these narratives warn against a cookie-cutter approach to institution building. The contributors are Daron Acemoglu, Maite Careaga, Gregory Clark, J. Bradford DeLong, Georges de Menil, William Easterly, Ricardo Hausmann, Simon Johnson, Daniel Kaufmann, Massimo Mastruzzi, Ian W. McLean, Lant Pritchett, Yingyi Qian, James A. Robinson, Devesh Roy, Arvind Subramanian, Alan M. Taylor, Jonathan Temple, Barry R. Weingast, Susan Wolcott, and Diego Zavaleta.