Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of rosemary essential oil and modified-atmosphere packaging (MAP) on meat quality and survival of pathogens in poultry fillets

The effect of rosemary (Rosmarinus officinalis L.) essential oil (REO) and modified-atmosphere packaging (MAP) on the survival of certain pathogens (Salmonella Typhimurium and Listeria monocytogenes) in poultry fillets and on their meat quality during 7 days of refrigerated storage were investigated. Because REO at 0.05% and 0.1% had weak antibacterial activity and REO at 0.3%, 0.5% and 1.0% imparted unacceptable organoleptic properties, only REO at 0.2% was used to treat the poultry meat. The results showed that adding 0.2% REO to poultry fillets did not reduce the size of the population of S. Typhimurium and L. monocytogenes. However, REO treatment significantly decreased the L* (lightness) value and increased the a* (redness) value of stored fillets, and adding REO in combination with MAP reduced the level of lipid oxidation. In conclusion, in a suitable combination, REO can be applied to improve the quality of meat, but further studies should be conducted to determine the appropriate commercial level for different meat products.
Direct temperature and salinity acoustic full waveform inversion

Recent work has shown that Full Waveform Inversion could be suitable to extract physical properties such as sound speed (c), density (ρ), temperature (T), and salinity (S) from the weak impedance contrasts associated with the ocean's thermohaline fine structure.The seismic inversion approaches proposed so far are based on the iterative inversion of c from multichannel seismic data, while the rest of parameters (T,S, and ρ) are determined in a second step using two equations of state and a local T‐S empirical relationship. In this work, we present an alternative to this approach. Using 1‐D synthetic seismic data, we demonstrate that the direct full waveform inversion of T and S using adjoint methods is feasible without the use of any local T‐S relationship and that the models of physical properties obtained with this approach are far more accurate than those inferred from c.
The National Cancer Data Base report on treatment patterns for hepatocellular carcinomas

The Commission on Cancer data from the National Cancer Data Base (NCDB) has previously reported data evaluating time trends in various cancers, including such elements as stage of disease at diagnosis, treatment, and survival for multiple tumor sites. In this report, data collected from 1985, 1986, 1990, 1991, 1995, and 1996 for primary hepatocellular carcinoma (HCC) tumors are presented.
Victimization in Different Contexts: Comments on the Special Issue

The eight contributions to this special issue provide an informative focus on many aspects of peer-based victimization in schools. Often using sophisticated quantitative and analytic procedures, they advance our knowledge in several important domains, pointing out important contextual variables, interactions, and mediating factors in the negative impact that experiences of victimization can bring about. Besides some comments on individual articles, this commentary raises some general issues about this and other research in the area, including the conceptual and definitional issues around victimization and the possibility of supplementing findings with insights from more qualitative methodologies.
Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity

This study was designed to better understand the molecular mechanisms involved in the anabolic resistance observed in elderly people. Nine young (22 ± 0.1 years) and 10 older (69 ± 1.7 years) volunteers performed a one-leg extension exercise consisting of 10 × 10 repetitions at 70% of their 3-RM, immediately after which they ingested 30 g of whey protein. Muscle biopsies were taken from the vastus lateralis at rest in the fasted state and 30 min after protein ingestion in the non-exercised (Pro) and exercised (Pro+ex) legs. Plasma insulin levels were determined at the same time points. No age difference was measured in fasting insulin levels but the older subjects had a 50% higher concentration than the young subjects in the fed state (p < 0.05). While no difference was observed in the fasted state, in response to exercise and protein ingestion, the phosphorylation state of PKB (p < 0.05 in Pro and Pro+ex) and S6K1 (p = 0.059 in Pro; p = 0.066 in Pro+ex) was lower in the older subjects compared with the young subjects. After Pro+ex, REDD1 expression tended to be higher (p = 0.087) in the older group while AMPK phosphorylation was not modified by any condition. In conclusion, we show that the activation of the mTORC1 pathway is reduced in skeletal muscle of older subjects after resistance exercise and protein ingestion compared with young subjects, which could be partially due to an increased expression of REDD1 and an impaired anabolic sensitivity.
Prospective Memory Performance in Non-Psychotic First-Degree Relatives of Patients with Schizophrenia: A Controlled Study

Objective We aimed at investigating prospective memory and its socio-demographic and neurocognitive correlates in non-psychotic, first-degree relatives (FDRs) of patients with schizophrenia compared to patients with first episode schizophrenia (FES), and healthy controls (HCs). Methods Forty-seven FES patients, 50 non-psychotic FDRs (23 offspring and 27 siblings) of patients with chronic schizophrenia (unrelated to the FES group) and 51 HCs were studied. The Chinese version of the Cambridge Prospective Memory Test (C-CAMPROMPT) was used to measure time-based prospective memory (TBPM) and event-based prospective memory (EBPM) performance. Other cognitive functions (involving respective memory and executive functions) were evaluated with standardized tests. Results After controlling for basic demographic characteristics including age, gender and educational level, there was a significant difference between FDRs, FES and HCs with respect to both TBPM (F(2,142) = 10.4, p<0.001) and EBPM (F(2,142) = 10.8, p<0.001). Multiple linear regression analyses revealed that lower scores of the Hopkins Verbal Learning Test-Revised (HVLT-R) and the STROOP Word-Color Test (SWCT) contributed to TBPM impairment, while lower educational level and higher scores of the Color Trails Test-2 (CTT-2) contributed to EBPM deficit in FDRs. Conclusions FDRs share similar but attenuated prospective memory impairments with schizophrenia patients, suggesting that prospective memory deficits may represent an endophenotype of schizophrenia.
Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy

Introduction: The efficacy of conventional therapy viz. finasteride and minoxidil in androgenetic alopecia (AGA) that is based on both preventing hair loss and promoting new hair growth, varies between 30% and 60%. This has led to a large number of patients unsatisfied who demand for a better cosmetic coverage over the scalp. Microneedling has recently been reported to be promising, effective and a safe treatment modality in the treatment of AGA. This augments the response of conventional therapy. Materials and Methods: Four men with AGA were on finasteride and 5% minoxidil solution since 2 to 5 years. Though there was no worsening in their respective AGA stages with the therapy, they showed no new hair growth. They were subjected to microneedling procedure over a period of 6 months along with their ongoing therapy. Patients were assessed with the use of the standardized 7-point evaluation scale and patients’ subjective hair growth assessment scale. The patients were followed up for 18 months post microneedling procedure to assess the sustainability of the response. Results: All patients showed a response of + 2 to + 3 on standardized 7-point evaluation scale. The response in the form of new hair growth started after 8-10 sessions. The patients’ satisfaction was more than 75% in three patients and more 50% in one patient, on patients’ subjective hair growth assessment scale. The obtained results were sustained post procedure during 18 months follow-up period. Conclusion Treatment with microneedling showed an accelerated response with addition of microneedling procedure leading to significant scalp density. This is the first case series to report the boosting effect of microneedling with respect to new hair follicle stimulation in patients with androgenetic alopecia who were poor responders to conventional therapy.
Tight closure and the Kodaira Vanishing Theorem.

In its familiär form, the Kodaira Vanishing Theorem is a Statement about the cohomology of the sheaf of sections of a positively curved line bündle <£ on a complex projective manifold X\ it asserts that H(X9&~) = Q for / less than the dimension of X. However, the Kodaira Vanishing Theorem also has a purely ideal-theoretic Interpretation concerning primary decompositions of ideals generated by part of a System of parameters for the section ring determined by <£. Moreover, the Kodaira Vanishing Theorem has a tight closure formulation, tying this classic and central result in complex algebraic geometry to new advances in characteristic p commutative algebra.
The measurement of information system use: preliminary considerations

The concept of system use has suffered from a "too simplistic definition" (DeLone and McLean [9], p. 16). This paper reviews various attempts at conceptualization and measurement of system use and then proposes a re-conceptualization of it as "the level of incorporation of an information system within a user's processes. " We then go on to develop the concept of a Functional Interface Point and four dimensions of system usage: automation level, the proportion of the business process encoded by the information system; extent, the proportion of the FIPs used by the business process; frequency, the rate at which FIPs are used by the participants in the process; and thoroughness, the level of use of information/functionality provided by the system at an FIP. The article concludes with a discussion of some implications of this re-conceptualization and areas for follow on research.
Salivary Secretory Disorders, Inducing Drugs, and Clinical Management

Background: Salivary secretory disorders can be the result of a wide range of factors. Their prevalence and negative effects on the patient's quality of life oblige the clinician to confront the issue. Aim: To review the salivary secretory disorders, inducing drugs and their clinical management. Methods: In this article, a literature search of these dysfunctions was conducted with the assistance of a research librarian in the MEDLINE/PubMed Database. Results: Xerostomia, or dry mouth syndrome, can be caused by medication, systemic diseases such as Sjögren's Syndrome, glandular pathologies, and radiotherapy of the head and neck. Treatment of dry mouth is aimed at both minimizing its symptoms and preventing oral complications with the employment of sialogogues and topical acting substances. Sialorrhea and drooling, are mainly due to medication or neurological systemic disease. There are various therapeutic, pharmacologic, and surgical alternatives for its management. The pharmacology of most of the substances employed for the treatment of salivary disorders is well-known. Nevertheless, in some cases a significant improvement in salivary function has not been observed after their administration. Conclusion: At present, there are numerous frequently prescribed drugs whose unwanted effects include some kind of salivary disorder. In addition, the differing pathologic mechanisms, and the great variety of existing treatments hinder the clinical management of these patients. The authors have designed an algorithm to facilitate the decision making process when physicians, oral surgeons, or dentists face these salivary dysfunctions.
Evolution of Mixed Rossby–Gravity Waves in Idealized MJO Environments

Abstract A linear shallow water model is used to simulate the evolution of mixed Rossby–gravity (MRG) waves in background states representative of the convective phase of the Madden–Julian oscillation (MJO). Initial MRG wave structures are obtained analytically. The MJO basic state is defined by the steady response of the tropical atmosphere to localized heating. Results from the simulations reveal that variations in the background flow play a significant role in the evolution of the MRG waves. When the basic state is symmetric about the equator, the MRG wave amplifies within the convergent region of the background flow and the ensuing development remains symmetric. When the heating is asymmetric, both the basic state and the MRG wave evolution exhibit significant asymmetries. Prominent features of this simulation are the development and growth of a series of small-scale, off-equatorial eddies that resemble tropical-depression-type disturbances. The results suggest that a persistent large-scale heating th.
Working Together: Examining the Effects of Parental and Community Involvement in Schools on School Delinquency

WORKING TOGETHER: EXAMINING THE EFFECTS OF PARENTAL AND COMMUNITY INVOLVEMENT IN SCHOOLS ON SCHOOL DELINQUENCY Erica Nicole Bower Old Dominion University, 2017 Director: Dr. Randy Myers How do we confront the problem of school delinquency? This study examined the impact of parental and community involvement in schools on school delinquency by employing a crosssectional secondary data analysis of the 2008 School Survey on Crime and Safety. Bivariate and multivariate analyses demonstrated that parental involvement in schools is significantly associated with and predictive of decreased school delinquency, while community involvement in schools is significantly associated with and predictive of increased school delinquency. Findings suggest that based on school administrator perceptions, stimulating parent involvement in schools and cultivating certain types of community involvement in schools may reduce delinquency occurrence and act as preventative forces against potential delinquency, decreasing reliance on reactive disciplinary policies.
Exploiting Lists of Names for Named Entity Identification of Financial Institutions from Unstructured Documents

There is a wealth of information about financial systems that is embedded in document collections. In this paper, we focus on a specialized text extraction task for this domain. The objective is to extract mentions of names of financial institutions, or FI names, from financial prospectus documents, and to identify the corresponding real world entities, e.g., by matching against a corpus of such entities. The tasks are Named Entity Recognition (NER) and Entity Resolution (ER); both are well studied in the literature. Our contribution is to develop a rule-based approach that will exploit lists of FI names for both tasks; our solution is labeled Dict-based NER and Rank-based ER. Since the FI names are typically represented by a root, and a suffix that modifies the root, we use these lists of FI names to create specialized root and suffix dictionaries. To evaluate the effectiveness of our specialized solution for extracting FI names, we compare Dict-based NER with a general purpose rule-based NER solution, ORG NER. Our evaluation highlights the benefits and limitations of specialized versus general purpose approaches, and presents additional suggestions for tuning and customization for FI name extraction. To our knowledge, our proposed solutions, Dict-based NER and Rank-based ER, and the root and suffix dictionaries, are the first attempt to exploit specialized knowledge, i.e., lists of FI names, for rule-based NER and ER.
P wave velocity variations in the Coso Region, California, derived from local earthquake travel times

Inversion of 4036 P wave travel time residuals from 429 local earthquakes using a tomographic scheme provides information about three-dimensional upper crustal velocity variations in the Indian Wells Valley-Coso region of southeastern California. The residuals are calculated relative to a Coso-specific velocity model, corrected for station elevation, weighted, and back-projected along their ray paths through models defined with layers of blocks. Slowness variations in the surface layer reflect local geology, including slow velocities for the sedimentary basins of Indian Wells and Rose valleys and relatively fast velocities for the Sierra Nevada and Argus Mountains. In the depth range of 3–5 km the inversion images an area of reduced compressional velocity in western and northern Indian Wells Valley but finds no major velocity variations beneath the Coso volcanic field to the north. These results are consistent with a recent study of anomalous shear wave attenuation in the Coso region. Between 5 and 10 km depth, low-velocity areas (7% slow) appear at the southern end of the Coso volcanics, reaching east to the Coso Basin. Numerical tests of the inversion's resolution and sensitivity to noise indicate that these major anomalies are significant and well-resolved, while other apparent velocity variations in poorly sampled areas are probably artifacts. The seismic data alone are not sufficient to uniquely characterize the physical state of these low-velocity regions. Because of the Coso region's history of Pleistocene bimodal volcanism, high heat flow, geothermal activity, geodetic deformation, and seismic activity, one possibility is to link the zones of decreased P velocity to contemporary magmatic activity.
Endogenous Human MDM2-C Is Highly Expressed in Human Cancers and Functions as a p53-Independent Growth Activator

Human cancers over-expressing mdm2, through a T to G variation at a single nucleotide polymorphism at position 309 (mdm2 SNP309), have functionally inactivated p53 that is not effectively degraded. They also have high expression of the alternatively spliced transcript, mdm2-C. Alternatively spliced mdm2 transcripts are expressed in many forms of human cancer and when they are exogenously expressed they transform human cells. However no study to date has detected endogenous MDM2 protein isoforms. Studies with exogenous expression of splice variants have been carried out with mdm2-A and mdm2-B, but the mdm2-C isoform has remained virtually unexplored. We addressed the cellular influence of exogenously expressed MDM2-C, and asked if endogenous MDM2-C protein was present in human cancers. To detect endogenous MDM2-C protein, we created a human MDM2-C antibody to the splice junction epitope of exons four and ten (MDM2 C410) and validated the antibody with in vitro translated full length MDM2 compared to MDM2-C. Interestingly, we discovered that MDM2-C co-migrates with MDM2-FL at approximately 98 kDa. Using the validated C410 antibody, we detected high expression of endogenous MDM2-C in human cancer cell lines and human cancer tissues. In the estrogen receptor positive (ER+) mdm2 G/G SNP309 breast cancer cell line, T47D, we observed an increase in endogenous MDM2-C protein with estrogen treatment. MDM2-C localized to the nucleus and the cytoplasm. We examined the biological activity of MDM2-C by exogenously expressing the protein and observed that MDM2-C did not efficiently target p53 for degradation or reduce p53 transcriptional activity. Exogenous expression of MDM2-C in p53-null human cancer cells increased colony formation, indicating p53-independent tumorigenic properties. Our data indicate a role for MDM2-C that does not require the inhibition of p53 for increasing cancer cell proliferation and survival.
Pipelined Recurrent Fuzzy Neural Networks for Nonlinear Adaptive Speech Prediction

A class of pipelined recurrent fuzzy neural networks (PRFNNs) is proposed in this paper for nonlinear adaptive speech prediction. The PRFNNs are modular structures comprising a number of modules that are interconnected in a chained form. Each module is implemented by a small-scale recurrent fuzzy neural network (RFNN) with internal dynamics. Due to module nesting, the PRFNNs offer a number of desirable attributes, including decomposition of the modeling task, enhanced temporal processing capabilities, and multistage dynamic fuzzy inference. Tuning of the PRFNN adaptable parameters is accomplished by a series of gradient descent methods with different weighting of the modules and the decoupled extended Kalman filter (DEKF) algorithm, based on weight grouping. Extensive experimentation is carried out to evaluate the performance of the PRFNNs on the speech prediction platform. Comparative analysis shows that the PRFNNs outperform the single-RFNN models in terms of the prediction gains that are obtained and computational efficiency. Furthermore, PRFNNs provide considerably better performance compared to pipelined recurrent neural networks, for models with similar model complexity.
Genetic variation of world soybean maturity date and geographic distribution of maturity groups

The maturity date of soybean (Glycine max (L.) Merr. ) is sensitive to photoperiod, which varies with latitude and growing seasons. The maturity group (MG) system, composed of 13 MGs, is a major approach in characterizing varieties’ ecological properties and adaptable areas. A total of 512 world soybean varieties, including 48 MG checks, were tested at a major site (Nanjing, 32.04°N) with portions tested in supplementary sites (Heihe, 50.22°N; Mudanjiang, 44.60°N; Jining, 35.38°N and Nanning, 22.84°N) in China to explore the world-wide MG distribution. The maturity date of the world soybean varied greatly (75–201 d) in Nanjing. Along with soybeans disseminated to new areas, the MGs further expanded during the last 70 years from MG I–VII to the early MG 0–000 in the north continents and to the late MG VIII–X in the south continents with the growth period structure differentiated into two subgroups in each MG 0–VIII except V. The cluster analysis among MGs and subgroups using genome-wide markers validated the MG sequential emergence order and the subgroup differentiation in eight MGs. For future evaluation, in addition to one major site (Nanjing), one supplementary southern site (Nanning) and one supplementary northern site (Heihe) are sufficient.
Equivariant operational Chow rings of $T$-linear schemes

We study T-linear schemes, a class of objects that in- cludes spherical and Schubert varieties. We provide a localization theorem for the equivariant Chow cohomology of these schemes that does not depend on resolution of singularities. Furthermore, we give an explicit presentation of the equivariant Chow cohomology of pos- sibly singular complete spherical varieties admitting a smooth equiv- ariant envelope (e.g., group embeddings).
βFTZ‐F1 dependent and independent activation of Edg78E, a pupal cuticle gene, during the early metamorphic period in Drosophila melanogaster

Insect metamorphosis is a developmentally important event for formation of adult structures from larval imaginal cells, and it is controlled by the ecdysteroid hormone. At the onset of metamorphosis, both the cuticle gene Edg78E and the transcription factor βFTZ‐F1 are expressed during the mid‐ to late prepupal period after a large ecdysteroid pulse. Edg78E mRNA is inducible by premature expression of βFTZ‐F1 and the Edg78E expression level is reduced in an ftz‐f1 mutant. Using a transgenic fly reporter assay, a 1.2 kb promoter region of the Edg78E gene has been identified, which was sufficient for appropriate temporally and spatially specific expression of the reporter gene LacZ. Within the promoter region, two βFTZ‐F1 binding sites are present and disruption of these sites reduced the expression level of the reporter gene. LacZ expression levels were dramatically reduced in the head and thorax regions but not affected in the abdominal region, suggesting that βFTZ‐F1 is required for high‐level Edg78E expression specifically in the head and thorax regions. The findings suggest that βFTZ‐F1 is a regulator for temporal gene expression at the onset of metamorphosis, and that complex mechanisms regulate the temporal and spatial regulation of gene expression during metamorphosis.