Miracle-dz/UniFAR-FTUs huggingface dataset:
Models for the study of nasal and sinus physiology in health and disease: A review of the literature

Chronic sinusitis is a very common yet poorly understood medical condition with significant morbidity. Hence, it remains an entity that is difficult to treat with unsatisfactory outcomes of current management options. This necessitates research into the etiology and pathophysiology of the condition to enhance our knowledge and the therapeutic options. Unfortunately, this kind of research is not always feasible on human subjects due to practical and ethical limitations. Therefore, an alternative model that simulates the disease had to be found in order to overcome these limitations. These models could either be in vivo or in vitro. The aim of our review is to summarize the research findings and key discoveries of both in vivo and in vitro models of chronic sinusitis that have enhanced our understanding of the condition today and have paved the way for the future research of tomorrow.
Self control of when and how much to test face–name pairs in a novel spaced retrieval paradigm: An examination of age-related differences

ABSTRACT Although the mnemonic benefit of spaced retrieval is well established, the way in which participants naturally space their own retrieval is relatively unexplored. To examine this question, a novel experimental paradigm was developed in which young and healthy older adults were given control over the frequency and timing of retrieval practice in the context of an ongoing reading task. Results showed that both age groups naturally expanded the intervals of their retrieval practice. When instructed, younger adults but not older adults were better able to employ equal spaced retrieval during retrieval practice. However, even under equal spaced retrieval instructions, young adults included an early retrieval attempt prior to equally spacing their retrieval. Although memory performance was equivalent, secondary task performance was reduced in the experimenter-instructed condition compared with the participant-selected condition. The results overall indicate that both younger and older participants naturally monitor their memory and efficiently use testing to titrate the number and timing of retrieval attempts used during the acquisition phase.
Self-Efficacy From the Perspective of Adolescents With LD and Their Specialist Teachers

This study used qualitative methodology to investigate the self-efficacy beliefs of early adolescents with learning disabilities (LD). We conducted a series of focus group interviews with 28 Grade 8 and 9 students with LD and individual interviews with 7 specialist LD teachers. Content analyses of the student and teacher data resulted in 2 a priori and 3 inductive themes: self-efficacy, calibration and levels of self-efficacy, students' self-awareness, attributions for failure, and problems and solutions. The students viewed themselves as low in self-efficacy and generally accurate in the calibration of their efficacy and performance, whereas the teachers viewed the students as overconfident about academic tasks. In contrast to the teachers, the students viewed verbal persuasion as a valued source of self-efficacy. Students attributed their failures to lack of effort, whereas their teachers attributed student failure to uncontrollable deficits. Problems and solutions related to student motivation were discussed from student and teacher perspectives.
Genetic evaluation of a proposed introduction: the case of the greater prairie chicken and the extinct heath hen

Population introduction is an important tool for ecosystem restoration. However, before introductions should be conducted, it is important to evaluate the genetic, phenotypic and ecological suitability of possible replacement populations. Careful genetic analysis is particularly important if it is suspected that the extirpated population was unique or genetically divergent. On the island of Martha's Vineyard, Massachusetts, the introduction of greater prairie chickens (Tympanuchus cupido pinnatus) to replace the extinct heath hen (T. cupido cupido) is being considered as part of an ecosystem restoration project. Martha's Vineyard was home to the last remaining heath hen population until its extinction in 1932. We conducted this study to aid in determining the suitability of greater prairie chickens as a possible replacement for the heath hen. We examined mitochondrial control region sequences from extant populations of all prairie grouse species (Tympanuchus) and from museum skin heath hen specimens. Our data suggest that the Martha's Vineyard heath hen population represents a divergent mitochondrial lineage. This result is attributable either to a long period of geographical isolation from other prairie grouse populations or to a population bottleneck resulting from human disturbance. The mtDNA diagnosability of the heath hen contrasts with the network of mtDNA haplotypes of other prairie grouse (T. cupido attwateri, T. pallidicinctus and T. phasianellus), which do not form distinguishable mtDNA groupings. Our findings suggest that the Martha's Vineyard heath hen was more genetically isolated than are current populations of prairie grouse and place the emphasis for future research on examining prairie grouse adaptations to different habitat types to assess ecological exchangeability between heath hens and greater prairie chickens.
Factor XIII V34L polymorphism modulates the risk of chronic venous leg ulcer progression and extension

Low Factor XIII (FXIII) activity has been reported in the blood of patients with chronic venous leg ulcer (CVU). In vivo studies have described increased wound healing in CVU patients treated with FXIII concentrate, and in vitro studies have shown increased regenerative capacity in FXIII‐treated fibroblasts. In addition, a common G‐to‐T polymorphism in the FXIIIA‐subunit gene (V34L) significantly increases the activity and modifies the cross‐linking properties of the FXIII molecule and this variant has been investigated as a protective factor against thrombosis, a recognized risk factor for CVU establishment. Therefore, the role of FXIII levels, FXIII V34L, FVR506Q, and FIIG20210A, common gene polymorphisms in the pathogenesis of CVU was investigated. Ninety‐one patients with CVU and 195 healthy controls (91 of them sex‐ and age‐matched) were PCR‐genotyped for the FXIIIV34L, FVR506Q, and FIIG20210A substitutions and FXIIIA‐subunit levels were determined by immuno‐electrophoresis. The extent of the venous ulcer surface in patients was measured by computer software. The allele frequency and the genotype distribution of the FXIII polymorphism did not show significant differences between the whole group of cases and controls as well as prothrombin variants did. On the contrary, the FVR506Q variant (FV Leiden) allele was more frequent in patients, yielding a significant OR value of 5.93 (95 percent CI, 1.83–19.17; p= 0.003). Considering only CVU cases secondary to a post–thrombotic syndrome (n= 24), FV Leiden yielded a greater OR value of 16.08 (95 percent CI, 4.33‐59.6; p < 0.0001). When the CVU cases were stratified by the three possible FXIII genotypes, a significant trend toward a lower mean value of the ulcerated area was clearly evident as the number of the polymorphic alleles (L34) increased in the genotype of patients (VV = 11.9 cm2,± 23.6; VL = 6.1 cm2,± 6.9; LL = 4.1 cm2,± 2.8; p= 0.01). On the other hand, FXIIIA antigen levels were similar between CVU cases and matched controls, but 11 percent of cases had FXIII deficiency (FXIIIA ≤ 0.65 U/ml; p= 0.003) and they showed a greater mean extension of the lesion if compared with the remaining cases without FXIIIA deficiency (14.5 cm2, ± 20.2 vs. 9.0 cm2, ± 6.3; p= 0.08). We conclude that FXIII antigen levels and FXIII V34L polymorphism may play a crucial role in the complex cascade of CVU pathophysiology, being significantly related to the CVU progression and extension because of the direct effects they have on the FXIII molecular activity.
Income Inequality, Redistribution and Poverty: Contrasting Rational Choice and Behavioural Perspectives

Based on the standard axiom of individual utility maximization, rational choice has postulated that higher income inequality translates into greater redistribution by shaping the median voter’s preferences. While numerous papers have tested this proposition, the literature has remained divided over the appropriate measure for redistribution. Revisiting the original contribution by Meltzer and Richard, the present paper argues that the median voter hypothesis implies that relative redistribution should increase in line with inequality. An empirical test based on 110 observations from the Luxembourg Income Study fails to find any support for the hypothesis. By contrast, voters’ actual preferences offer a better guide to understanding redistributive outcomes. The findings challenge the narrow concept of human motivation that underpins rational choice, and point to the importance of fairness orientations that have been emphasized in behavioural economics.
SPH Fluids in Computer Graphics

Smoothed Particle Hydrodynamics (SPH) has been established as one of the major concepts for ﬂuid animation in computer graphics. While SPH initially gained popularity for interactive free-surface scenarios, it has emerged to be a fully ﬂedged technique for state-of-the-art ﬂuid animation with versatile effects. Nowadays, complex scenes with millions of sampling points, one-and two-way coupled rigid and elastic solids, multiple phases and additional features such as foam or air bubbles can be computed at reasonable expense. This state-of-the-art report summarizes SPH research within the graphics community.
Examining the Antecedents of Behavioral Intentions in a Tourism Context

The purpose of this study was to gain an understanding of the structure and antecedents of travelers' behavioral intentions. Understanding travelers' behavioral intentions is an important goal of both destination marketing organizations and host destinations. However, little research has contributed to the theoretical development in this area, and the lack of a solid theoretical framework has negatively influenced the validity of existing research. Thus, this study attempted to explain travelers' behavioral intentions, using a model which was developed based on existing human behavior theories: the theory of reasoned action and the theory of planned behavior. Another major objective of the current study was to test the validity of the proposed model. Based on the theory of reasoned action and the theory of planned behavior, a conceptual framework was established to explain travelers' behavior intention in a tourism context. Attitude was conceptualized as destination image which is a two-dimensional construct including cognitive and affective components. Subjective norms were conceptualized as the combination of normative beliefs and motivation to comply. Perceived behavioral control was conceptualized as constraints which is a three-dimensional construct including intrapersonal, interpersonal, and structural components. An online panel survey was launched in September 2008 to collect data. Respondents were specially asked their perceived image about Texas, what were the barriers preventing them from traveling to Texas, and how their reference groups affected their travel decision to Texas. Totally, 1,448 completed surveys were received and utilized for analysis which included both visitors and non-visitors. The data analysis procedures included six major steps, from descriptive analysis and preliminary data analysis, to model and hypothesis testing. To do so, the Statistical Package for the Social Sciences 16.0 (SPSS) and Amos 16.0 were utilized. The structural relationships between all variables were tested with using structural equation modeling (SEM). Results of the study showed that destination image and subjective norm positively impacted behavioral intentions while constraints negatively affected behavioral intentions. Hence, this research provides important direction for the development of a more comprehensive theoretical framework to explain travelers' behavioral intentions, and presented a step toward offering practical as well as theoretical implications for future research.
Anytime solution optimization for sampling-based motion planning

Recent work in sampling-based motion planning has yielded several different approaches for computing good quality paths in high degree of freedom systems: path shortcutting methods that attempt to shorten a single solution path by connecting non-consecutive configurations, a path hybridization technique that combines portions of two or more solutions to form a shorter path, and asymptotically optimal algorithms that converge to the shortest path over time. This paper presents an extensible meta-algorithm that incorporates a traditional sampling-based planning algorithm with offline path shortening techniques to form an anytime algorithm which exhibits competitive solution lengths to the best known methods and optimizers. A series of experiments involving rigid motion and complex manipulation are performed as well as a comparison with asymptotically optimal methods which show the efficacy of the proposed scheme, particularly in high-dimensional spaces.
In Defense of Tasks and TBLT: Nonissues and Real Issues

ABSTRACT The first aim of this article, addressed in section 1, is to define what is meant, and not meant, by task and task-based language teaching (TBLT). The second is to summarize and evaluate 14 criticisms that have been made of both. Section 2 responds to five alleged problems with TBLT's psycholinguistic rationale, section 3 to six at the classroom level, and section 4 to three claimed problems with implementing TBLT in specific contexts. A few of the criticisms touch on important matters, but most, I will suggest, are nonissues. The third aim of the article is to identify some genuine problems in need of resolution—real issues—and briefly to illustrate research programs under way to address them.
A school consultation intervention for adolescents with ADHD: barriers and implementation strategies.

BACKGROUND Academic impairment is among the most troubling domains of impairment for adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). METHOD This investigation presents results of a yearlong academic intervention delivered to adolescents with ADHD (N = 218) by engaging school staff as interventionists through behavioral consultation with an outside mental health professional. RESULTS The intervention was coordinated successfully in some cases, but not in others. The principal challenge to intervention coordination was sustaining monthly contact between consultants and interventionists (38.5% success rate) and scheduling in-person consultation meetings with interventionists (40.0% success rate). Implementation of the intervention was enhanced when the student (a) attended a public (vs. private) school, (b) had an IEP or Section 504 plan in place, (c) was in middle school (vs. high school), (d) had a parent who communicated regularly with the school, and (e) had a special education support staff member or counselor (vs. teacher or administrator) as a school interventionist. CONCLUSIONS Considering these data, recommendations are provided for effective coordination of academic interventions for adolescents with ADHD.
Haptic, visual and visuo-haptic softness judgments for objects with deformable surfaces

The purpose of this study is to investigate multisensory visual-haptic softness perception using deformable objects. We created a set of rubber specimens, whose compliance varied in a controlled fashion (0.11 to 0.96 mm/N), but which were otherwise indistinguishable. Participants judged the magnitude of the stimuli according to their softness under haptic-only, vision-only and visuo-haptic conditions. In haptic and visuo-haptic conditions participants explored the stimuli without and with vision of their exploratory movements, respectively. In visual conditions, participants watched how another person explored the stimuli. Participants were well able to differentiate between the different stimuli under all three modality conditions. Stimuli were judged to be slightly softer under vision-only conditions than under haptic-only conditions; visuo-haptic judgments were in-between (average visual weight: 55%). These findings demonstrate that a) participants can reliably infer softness from indirect visual information alone-that is from watching corresponding exploratory movements and stimulus deformations-, and that b) such visual information has a major contribution to visuo-haptic softness judgments. We further observed that judgments were more variable under visual as compared to haptic conditions; the variability of visuo-haptic judgments was similar to that of haptic ones. The lack of benefit from adding visual to haptic information, and the contrast between the relatively high visual weight in visuo-haptic judgments on the one hand and the low reliability of visual relative to haptic-only information on the other hand, suggest that the integration of visual and haptic judgments was not optimal, but biased towards vision.
Making sense of Moroccan tribal sociology and history

The concept of tribe has long been contentious in North African history and anthropology and the idealised concept of segmentary lineage theory is inadequate. Segmentation, however, is a useful concept as it corresponds to tribal self image and cohesion although it undermines chronology. Nonetheless, tribal groupings can be of great antiquity, as patterns of tribal migration make clear, although it is only as a result of the colonial period that their toponymic realities have been permanently determined.
Functional Impairment as a Variable in Adjustment Post-Combat

This study examined how functional impairment relates to postcombat adjustment over time, controlling for the influence of combat exposure. Analyses used sequential random coefficient models to examine 2 hypotheses: a) combat exposure and functional impairment predict the change in posttraumatic stress, depression, and anger/aggression symptoms during the first year postcombat; and b) combat exposure and functional impairment at reintegration predict symptom scores at 1 year postdeployment. A Brigade Combat Team completed surveys at reintegration, 4 months, and 12 months after a 1-year deployment to Iraq. Soldiers reporting high functional impairment at reintegration had higher symptoms at both follow-up periods, and functional impairment was a significant predictor of symptoms at the last time point, even after accounting for the influence of combat exposure. There was also an interaction effect, such that functional impairment exacerbated the impact of combat exposure on posttraumatic stress and anger/aggression symptoms at 12 months postdeployment.
To Be or Not to Be (Black or Multiracial or White)

Culture shapes the meaning of race and, consequently, who is placed into which racial categories. Three experiments conducted in the United States and Brazil illustrated the cultural nature of racial categorization. In Experiment 1, a target’s racial ancestry influenced Americans’ categorizations but had no impact on Brazilians’ categorizations. Experiment 2 showed cultural differences in the reliance on two phenotypic cues to race; Brazilians’ categorizations were more strongly determined by skin tone than were Americans’ categorizations, and Americans’ categorizations were more strongly determined by other facial features compared to Brazilians' categorizations. Experiment 3 demonstrated cultural differences in the motivated use of racial categories. When the racial hierarchy was threatened, only Americans more strictly enforced the Black–White racial boundary. Cultural forces shape the conceptual, perceptual, and ideological construal of racial categories.
Motor changes in presymptomatic Huntington disease gene carriers.

OBJECTIVE To determine whether changes in motor function and reaction time are present in presymptomatic individuals carrying the Huntington disease (HD) allele. DESIGN A case-control, double-blind study comparing asymptomatic at-risk subjects, with or without the HD allele, and subjects clinically determined to have early manifest HD. SETTING The Department of Medical and Molecular Genetics at Indiana University School of Medicine, Indianapolis. PARTICIPANTS We studied 383 patients at risk for HD. Each subject was asymptomatic by self-report. MEASURES Genotype for the HD allele was determined by polymerase chain reaction testing. A battery of 8 physiological tests measuring speed of movement and reaction time was performed with a computer-driven system. RESULTS Following neurologic examination, 17 of the 120 gene carriers (GCs) had symptoms sufficient for a clinical diagnosis of manifest HD. The remaining 103 GCs were designated presymptomatic GCs. When the non-GCs were compared with the presymptomatic GCs (1-way analysis of covariance and the Fisher protected t test), results on 3 of the 8 physiological tests--movement time, movement time with decision, and auditory reaction time--were different. Additionally, the number of trinucleotide (CAG) repeats significantly correlated with test performance for movement time with decision and visual reaction time with decision when both the entire group of GCs and the presymptomatic GCs alone were considered. CONCLUSION These results suggest that subtle subclinical changes in motor function are present in presymptomatic individuals who have inherited the HD allele.
Sexual behaviour among people with HIV according to self-reported antiretroviral treatment and viral load status

Objective:To assess, among people with HIV, the association of self-reported antiretroviral treatment (ART) and viral load status with condomless sex with an HIV-serodifferent partner (CLS-D). Design:Cross-sectional study of 3258 HIV-diagnosed adults in the United Kingdom, 2011–2012. Methods:CLS-D in the past 3 months and self-reported ART/viral load were ascertained by questionnaire. Clinic-recorded viral load was documented. HIV-transmission risk sex (CLS-D-HIV-risk) was defined as CLS-D together with either not on ART or clinic-recorded viral load more than 50 copies/ml. Results:Of 3178 participants diagnosed more than 3 months ago, 2746 (87.9%) were on ART, of whom self-reported viral load was ‘50 copies/ml/ or less/undetectable’ for 78.4%; ‘more than 50 copies/ml/detectable’ for 8.3%; ‘do not know/missing’ for 13.3%. CLS-D prevalence was 14.9% (326/2189), 6.4% (23/360) and 10.7% (67/629) among men who have sex with men, heterosexual men and women, respectively. Among men who have sex with men, CLS-D prevalence was 18.8% among those not on ART; 15.2% among those on ART with undetectable self-reported viral load; 9.8% among those on ART without undetectable self-reported viral load. Compared with ‘on ART with undetectable self-reported viral load’, prevalence ratios (95% confidence interval) adjusted for demographic/HIV-related factors were: 0.66 (0.45, 0.95) for ‘on ART without undetectable self-reported viral load’, and 1.08 (0.78, 1.49) for ‘not on ART’ (global P = 0.021). Among heterosexual men and women (combined), ART/self-reported viral load was not associated with CLS-D [corresponding adjusted prevalence ratios: 1.14 (0.73, 1.79) for ‘on ART without undetectable self-reported viral load’; 0.88 (0.44, 1.77) for ‘not on ART’, P = 0.77]. CLS-D-HIV-risk prevalence was 3.2% among all participants; 16.1% for ‘not on ART’; 0.6% for ‘on ART with undetectable self-reported viral load; 4.2% for ‘on ART without undetectable self-reported viral load. ’ Conclusion:Use of ART was not associated with increased prevalence of CLS-D, and was associated with greatly reduced prevalence of HIV-transmission risk sex.