Miracle-dz/UniFAR-FTUs huggingface dataset:
Cohomology of Invariant Drinfeld Twists on Group Algebras

We show how to compute a certain group of equivalence classes of invariant Drinfeld twists on the algebra of a finite group G over a field k of characteristic zero. This group is naturally isomorphic to the second lazy cohomology group of the Hopf algebra of k-valued functions on G. When k is algebraically closed, the answer involves the group of outer automorphisms of G induced by conjugation in the group algebra as well as the set of all pairs (A, b), where A is an abelian normal subgroup of G and is a k × -valued G-invariant nondegenerate alternating bilinear form on the dual . When the ground field k is not algebraically closed, we use algebraic group techniques to reduce the computation of H l 2 (G) to a computation over the algebraic closure. As an application of our results, we compute H l 2 (G) for a number of groups.
A noninvasive protocol for anterior temporal lobectomy

We report the results of a protocol for choosing candidates for temporal lobectomy using a standard battery of objective tests without intracranial electrodes. We assigned each test a level of importance, and an algorithm was used to determine whether temporal lobectomy could be performed. Fifty-one patients (total pool, 103 patients) met protocol requirements and had an anterior temporal lobectomy with a mean follow-up of 39.4 months (range, 21 to 64 months), most remaining on anticonvulsant therapy. Eighty percent are seizure free, 12% have <3 seizures per year or only nocturnal seizures, and 8% have >80% reduction in seizure frequency. One-third of patients who failed protocol criteria did not have temporal lobe seizures when studied with intracranial electrodes. We analyzed and modified the algorithm after comparing these patients with others who were poor candidates for temporal lobectomy. We conclude that this protocol is effective and recommend using such an objective algorithm.
Effect of a toxin produced by Haemophilus influenzae on ciliated respiratory epithelium.

Tracheal organ cultures from the human fetus, the chick embryo, and several rodents were used in a study of the effect of Haemophilus influenzae on respiratory ciliated epithelial cells. H. influenzae grew in medium containing tracheal organ cultures from different sources, resulting in ciliostasis after various periods of time. Supernatant fluids of cultures of H. influenzae contained a ciliostatic substance that was active at high dilution in rat tracheal organ cultures. Cultures of human fetus and chick trachea were less sensitive, and some human fetal tracheas were insensitive. Histologic studies showed loss of cilia, damage to epithelial cells, and sloughing. The ciliostatic substance was produced early in the growth cycle of H. influenzae, was released into the medium, was nondialyzable, and was stable in heat. This substance was produced by all types and strains of H. influenzae tested. The possibility that the ciliostatic substance was an endotoxin was proposed, and the role of this substance in the pathogenesis of infections of the respiratory tract due to H. influenzae was considered.
Depression in Post‐Acute Myocardial Infarction Patients

Purpose To identify strategies for nurse practitioners to diagnose and treat depression following acute myocardial infarction (AMI) and prevent sub‐sequent cardiac events. Data sources Selected articles in the medical and psychiatric literature and government consensus guidelines. Conclusions Between 8% and 45% of patients who have suffered an AMI exhibit symptoms of major depression. Depression is an independent risk factor for cardiovascular disease and causes higher morbidity and mortality rates among patients with coronary artery disease. Implications for practice Early diagnosis and aggressive treatment are crucial to reducing cardiac related morbidity and mortality. Cardiac rehabilitation pro‐grams, psychotherapy and counseling, and pharmacotherapy are effective in the management of AMI depression.
Abandoned Object Detection via Temporal Consistency Modeling and Back-Tracing Verification for Visual Surveillance

This paper presents an effective approach for detecting abandoned luggage in surveillance videos. We combine short- and long-term background models to extract foreground objects, where each pixel in an input image is classified as a 2-bit code. Subsequently, we introduce a framework to identify static foreground regions based on the temporal transition of code patterns, and to determine whether the candidate regions contain abandoned objects by analyzing the back-traced trajectories of luggage owners. The experimental results obtained based on video images from 2006 Performance Evaluation of Tracking and Surveillance and 2007 Advanced Video and Signal-based Surveillance databases show that the proposed approach is effective for detecting abandoned luggage, and that it outperforms previous methods.
Autocrine Motility Factor Receptor Expression Implies an Unfavourable Prognosis in Resected Stage I Pulmonary Adenocarcinomas

Abstract Background : Pulmonary adenocarcinomas constitute a different histological subtype among the histological subtypes of non small cell lung carcinomas by showing comparably unfavourable rates of prognosis and different immunobiological features. Autonomous motility of tumour cells plays an important role in the regulation of local invasion and distant metastasis of tumour lesions which have great impact on overall survival. AMF (Autocrine motility factor) is a tumour secreted cytokine that stimulates motility during invasion and metastasis via its receptor, AMFR. We conducted an immunohistochemical study to investigate AMFR expression in pulmonary adenocarcinomas and its effect on survival. Material and methods : We assessed AMFR expression using a monoclonal antibody (3F3A) in a total of 32 surgical specimens with stage I pulmonary adenocarcinomas that underwent curative resection. We analyzed AMFR expression as a possible prognostic factor on survival and its correlations with clinicopathological features. Results : A total of 19 (59.3%) specimens showed AMFR expression. The 3-year survival rates of AMFR positive and AMFR negative patients were 47.3% and 84.6%, respectively, which was a significant difference (P = 0.0197). The univariate predictors of surgical outcome were AMFR expression (P = 0.032) and perineural invasion (P = 0.038). However, multivariate analysis revealed AMFR expression (P = 0.045) as the only independent prognostic factor. Conclusions : AMFR expression predicts an unfavourable surgical outcome in patients with stage I pulmonary adenocarcinomas.
Dynamic hygroexpansion of paperboards

The dynamic response of paperboard dimensions to changes in ambient relative humidity have been investigated. The strains were measured in two experiments that were different with respect to the interaction of the specimen with the surrounding air. The difference had a clear effect on the strain rate even when the rate of change of the relative humidity was the same. The strain rate was faster than the rate of moisture content change and appeared to depend on the internal stress state of the fiber network as MD and CD strains had different rates.
Critical thinking ability of new graduate and experienced nurses.

AIM This paper is a report of a study to identify critical thinking learning needs of new and experienced nurses. BACKGROUND Concern for patient safety has grown worldwide as high rates of error and injury continue to be reported. In order to improve patient safety, nurses must be able to recognize changes in patient condition, perform independent nursing interventions, anticipate orders and prioritize. METHODS In 2004-2006, a consecutive sample of 2144 newly hired nurses in a university-affiliated healthcare system completed the Performance Based Development System Assessment consisting of 10 videotaped vignettes depicting change in patient status. Results were reported as meeting or not meeting expectations. For nurses not meeting expectations, learning needs were identified in one of six subcategories. RESULTS Overall, 74.9% met assessment expectations. Learning needs identified for nurses not meeting expectations included initiating independent nursing interventions (97.2%), differentiation of urgency (67%), reporting essential clinical data (65.4%), anticipating relevant medical orders (62.8%), providing relevant rationale to support decisions (62.6%) and problem recognition (57.1%). Controlling for level of preparation, associate (P=0.007) and baccalaureate (P<0.0001) nurses were more likely to meet expectations as years of experience increased; a similar trend was not seen for diploma nurses (P=0.10). Controlling for years of experience, new graduates were less likely to meet expectations compared with nurses with >or=10 years experience (P=0.046). CONCLUSION Patient safety may be compromised if a nurse cannot provide clinically competent care. Assessments such as the Performance Based Development System can provide information about learning needs and facilitate individualized orientation targeted to increase performance level.
Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer

For locally advanced and metastatic head and neck squamous cell carcinoma (HNSCC), the current clinical use of Cetuximab in chemo/radiotherapy protocols is often associated to severe systemic toxicity. Here we report in vitro data in human FaDu pharynx SCC cells, showing that inactive concentrations of biotinylated Cetuximab (bCet) become active upon anchorage to AvidinOX on the surface of tumor cells. AvidinOX-anchored bCet induces apoptosis and DNA damage as well as specific inhibition of signaling, degradation and abrogation of nuclear translocation of EGFR. In the mouse model of FaDu cancer, we show that intra-tumor injection of AvidinOX allows anti-tumor activity of an otherwise inactive, intraperitoneally delivered, low dose bCet. Consistently with in vitro data, in vivo tumor inhibition is associated to induction of apoptosis, DNA damage and reduced angiogenesis. AvidinOX is under clinical investigation for delivering radioactive biotin to inoperable tumors (ClinicalTrials.gov NCT02053324) and present data support its use for the local treatment of HNSCC in combination with systemic administration of low dose bCet.
Cerebellocerebral Diaschisis Is the Likely Mechanism of Postsurgical Posterior Fossa Syndrome in Pediatric Patients with Midline Cerebellar Tumors

BACKGROUND AND PURPOSE: PFS occurs in approximately 25% of pediatric patients receiving surgery for midline posterior fossa tumors. Increasing evidence suggests that PFS represents a complex supratentorial cortical dysfunction related to surgery-induced disruption of critical cerebellocerebral connections. The purpose of this study was to determine whether a consistent surgical damage pattern may be identified in patients with PFS by early postoperative anatomic imaging analysis of the pECP and to test whether DSC can detect corresponding changes in cerebral cortical perfusion to indicate a secondary, remote functional disturbance, which could suggest a diaschisis-like pathomechanism. MATERIALS AND METHODS: Eleven patients with postoperative PFS were evaluated retrospectively and were paired with age- and sex-matched control subjects in whom PFS did not develop. MR imaging work-up included DSC within 3 to 4 weeks after surgery as well as early postoperative anatomic imaging to evaluate components of the pECP. RESULTS: DSC showed significant decreases in CBF within frontal regions (P < .05) and a trend to global cerebral cortical hypoperfusion in patients with PFS. Logistic regression analysis suggested a strong (potentially predictive) relationship between bilateral damage to pECP and the development of PFS (P = .04). CONCLUSIONS: Our data suggest that the primary cause of PFS is the bilateral surgical damage to the pECP. This leads to a trans-synaptic cerebral cortical dysfunction (a form of bilateral crossed cerebellocerebral diaschisis), which manifests with DSC-detectable global, but dominantly frontal, cortical hypoperfusion in patients with patients with PFS compared with age- and sex-matched control subjects.
Learning Detection with Diverse Proposals

To predict a set of diverse and informative proposals with enriched representations, this paper introduces a differentiable Determinantal Point Process (DPP) layer that is able to augment the object detection architectures. Most modern object detection architectures, such as Faster R-CNN, learn to localize objects by minimizing deviations from the ground truth, but ignore correlation between multiple proposals and object categories. Non-Maximum Suppression (NMS) as a widely used proposal pruning scheme ignores label-and instance-level relations between object candidates resulting in multi-labeled detections. In the multi-class case, NMS selects boxes with the largest prediction scores ignoring the semantic relation between categories of potential election. In contrast, our trainable DPP layer, allowing for Learning Detection with Diverse Proposals (LDDP), considers both label-level contextual information and spatial layout relationships between proposals without increasing the number of parameters of the network, and thus improves location and category specifications of final detected bounding boxes substantially during both training and inference schemes. Furthermore, we show that LDDP keeps it superiority over Faster R-CNN even if the number of proposals generated by LDPP is only ~30% as many as those for Faster R-CNN.
First In Vivo Optical Coherence Tomography in the Human Bile Duct

BACKGROUND AND STUDY AIMS Optical coherence tomography (OCT) is a novel technique for performing high-resolution, cross-sectional tomographic imaging in human tissue, which allows resolution of up to 10 microm. The short depth of penetration allows assessment of the superficial 2 mm of the gastrointestinal tract, an area that is difficult to appraise even with high-frequency ultrasound. This is the first report on in vivo OCT of the human biliary system. The aim was to assess the feasibility of the technique. PATIENTS AND METHODS Four cases of intraductal OCT are presented. The probe was inserted through the working channel of a duodenoscope. RESULTS The connective tissue layer and the underlying retroperitoneal tissue, with less backscattering, could be clearly demonstrated. The images showed a layer architecture which was similar to that found histologically. CONCLUSIONS OCT of the biliary system is feasible in patients with biliary pathology. Interpretable images were obtained, and clinical use needs further assessment. As current OCT probes and processors do not yet provide optimal resolution, further generations of equipment with improved image quality are required.
Association Between Presence of Virulence Genes and Antibiotic Resistance in Clinical Klebsiella Pneumoniae Isolates.

OBJECTIVE To investigate the presence of rmpA and wcaG virulence genes and Class 1, 2, and 3 integrons, and to evaluate a relationship between antibiotic resistance and virulence in Klebsiella pneumoniae METHODS: We collected a total of 200 K. pneumoniae isolates from hospitals in Tehran, Iran. Antibiotic susceptibility was determined using the disk diffusion method. The extended-spectrum β-lactamase (ESBL) producers were detected using the combination disk method. We detected the rmpA and wcaG genes and class 1, 2, and 3 integrons via polymerase chain reaction (PCR). The χ2 test was used for statistical evaluation. RESULTS Of 200 isolates, 115 (57.5%) were ESBL producers; 74.0% carried the class 1 integron, and 1.0% carried the class 2 integron. The gene rmpA was detected in 7% of isolates and the gene wcaG in 23.5% of isolates. Integron-positive isolates showed a higher prevalence of wcaG compared with to integron-negative isolates (P <.05). CONCLUSION Our results showed a correlation between presence of virulence gene and antibiotic resistance in K. pneumoniae.
From the Office of Technology Assessment.

In response to Congressional requests that it study the implications of the wide-spread use of DNA-based CF (cystic fibrosis) carrier tests, the Office of Technology Assessment published the report Cystic Fibrosis and DNA Tests: Implications of Carrier Screening (Washington: OTA; 1992). This article briefly summarizes the report's conclusions.
Robust static output feedback variable structure control for nonlinear systems

In this paper, a robust stabilization problem for nonlinear systems is investigated using static output feedback. Matched and mismatched uncertainties are considered and their bounding functions take general forms. Based on a Lyapunov analysis approach and sliding mode techniques, some conclusions are presented. Then, a robust nonlinear variable structure control scheme is synthesized to stabilize the system globally, and it is not necessary for the nominal system to be linearizable globally. The conservatism is reduced by using uncertainty bounds in the control design. Finally, a mass–spring system is employed to illustrate the effectiveness of the results.
Refractive errors in Cameroonians diagnosed with complete oculocutaneous albinism

Background Albinism causes significant eye morbidity and amblyopia in children. The aim of this study was to determine the refractive state in patients with complete oculocutaneous albinism who were treated at the Gynaeco-Obstetric and Paediatric Hospital, Yaoundé, Cameroon and evaluate its effect on vision. Methods We carried out this retrospective study at the ophthalmology unit of our hospital. All oculocutaneous albino patients who were treated between March 1, 2003 and December 31, 2011 were included. Results Thirty-five patients (70 eyes) diagnosed with complete oculocutaneous albinism were enrolled. Myopic astigmatism was the most common refractive error (40%). Compared with myopic patients, those with myopic astigmatism and hypermetropic astigmatism were four and ten times less likely, respectively, to demonstrate significant improvement in distance visual acuity following optical correction. Conclusion Managing refractive errors is an important way to reduce eye morbidity-associated low vision in oculocutaneous albino patients.
Modelling Heterogeneity With and Without the Dirichlet Process

We investigate the relationships between Dirichlet process (DP) based models and allocation models for a variable number of components, based on exchangeable distributions. It is shown that the DP partition distribution is a limiting case of a Dirichlet–multinomial allocation model. Comparisons of posterior performance of DP and allocation models are made in the Bayesian paradigm and illustrated in the context of univariate mixture models. It is shown in particular that the unbalancedness of the allocation distribution, present in the prior DP model, persists a posteriori. Exploiting the model connections, a new MCMC sampler for general DP based models is introduced, which uses split/merge moves in a reversible jump framework. Performance of this new sampler relative to that of some traditional samplers for DP processes is then explored.
In the Eye of the Beholder: The Impact of Frame Rate on Human Eye Blink

We introduce a study investigating the impact of high frame rate videos on viewer's eye blink frequency. A series of videos with varying combinations of motion complexities and frame rates were shown to participants, while their eye blinks were counted with J! NS MEME (smart eye wear). Lower frame rates and lower motion complexity caused higher blink frequencies, which are markers for stress and emotional arousal.
Pneumocephalus: Effects of Patient Position on the Incidence and Location of Aerocele after Posterior Fossa and Upper Cervical Cord Surgery

The incidence of pneumocephalus and factors contributing to its occurrence were studied retrospectively in 100 consecutive patients who underwent posterior fossa or cervical cord surgery in the sitting, park-bench, and prone positions. Supine skull x-ray films taken immediately postoperatively were used to determine the presence of intracranial air. Surgery in the sitting position uniformly resulted in pneumocephalus (32/32 patients). Pneumocephalus also occurred frequently among patients in the park-bench (29/40) and prone positions (16/28). Intraventricular air occurred more frequently when patients were in the sitting position (25/32) than in the two other surgical positions (3/29 and 4/16, respectively, P < 0.001). The high incidence of pneumocephalus and of intraventricular air that occurred when patients were in the sitting position is attributed to the large amount of cerebrospinal fluid drained due to gravitational effect. When surgical position is considered one of the contributing factors, only position significantly affected the frequencies of pneumocephalus and intraventricular air accumulation. None of the 77 patients with pneumocephalus suffered neurologic change related to the presence of intracranial air. We conclude the following: pneumocephalus commonly occurs after posterior fossa or cenvical cord surgeries, particularly when the surgery is performed in the sitting position; neurologic change caused by pneumocephalus is a rare complication after posterior fossa craniotomy; when a patient with coexisting hydrocephalus undergoes surgery, if the patient is in the sitting position, there is an increased risk of trapping a large amount of intracranial air.
Bonfils assisted double lumen endobronchial tube placement in an anticipated difficult airway

The role of various airway adjuncts in the management of difficult airway has been described in the literature. Bonfils rigid fiberscope is one of the airway assist devices widely used for endotracheal intubation in the individuals with cervical instability warranting limited neck movements. With our experience in the utilization of Bonfils for single lumen endotracheal tube placement, we are increasingly using for double lumen endobronchial (DLT) intubation as well. We would like to describe our experience in the use of Bonfils for DLT placement and outline the merits and limitations of the other suitable airway assist devices in this report. The double lumen tube has to be modified by decreasing the length of DLT to accommodate the Bonfils fiberscope and this is applicable only in certain type of double lumen tubes for e.g. Bronchocath.
Cruciferous Vegetables: Cancer Protective Mechanisms of Glucosinolate Hydrolysis Products and Selenium

Dietetic professionals urge Americans to increase fruit and vegetable intakes. The American Institute of Cancer Research estimates that if the only dietary change made was to increase the daily intake of fruits and vegetables to 5 servings per day, cancer rates could decline by as much as 20%. Among the reasons cited for this health benefit are that fruits and vegetables are excellent sources of fiber, vitamins, and minerals. They also contain nonnutritive components that may provide substantial health benefits beyond basic nutrition. Examples of the latter are the glucosinolate hydrolysis products, sulforaphane, and indole-3-carbinol. Epidemiological studies provide evidence that the consumption of cruciferous vegetables protects against cancer more effectively than the total intake of fruits and vegetables. This review describes the anticarcinogenic bioactivities of glucosinolate hydrolysis products, the mineral selenium derived from crucifers, and the mechanisms by which they protect against cancer. These mechanisms include altered estrogen metabolism, protection against reactive oxygen species, altered detoxification by induction of phase II enzymes, decreased carcinogen activation by inhibition of phase I enzymes, and slowed tumor growth and induction of apoptosis.