Miracle-dz/UniFAR-FTUs huggingface dataset:
A critical review of the Couvade syndrome: the pregnant male

The Couvade syndrome is a global phenomenon occurring in industrialised countries around the world and has a wide international variance. It affects biological fathers particularly during the first and third trimesters of pregnancy with cessation of symptoms upon birth or shortly within the postpartum period. It does not appear in the nosology of the Diagnostic Statistical Manual of Mental Disorders: DSM—Version 4 (American Psychiatric Association, 2000) on the ICD—Version 10 (WHO, 1993). Nevertheless, early accounts tended to medicalise it as a psychosomatic disorder. Its relationship with socio‐demographic factors is inconsistent, with the exception of ethnicity. International studies reveal some contradictory findings in the type of symptoms. This may reflect methodological problems in the syndrome's definition or criteria and type of measurement across studies. A plethora of theories has been put forward to account for the origins of the syndrome. Psychoanalytical theories contend that it is a consequence of the man's envy of the woman's procreative ability or foetal rivalry. Psychosocial theories propose that it occurs due to the marginalisation of fatherhood and as part of a transitional crisis to parenthood. Paternal theories suggest a connection between the man's involvement in pregnancy, role preparation and the syndrome. However, some of these theories have not been thoroughly investigated. Those which have reveal inconsistent findings. It is recommended that future investigators use qualitative approaches to further illuminate the syndrome's characteristics, definition and perceptions as seen by male partners. This should be followed by quantitative approaches of large heterogeneous samples to investigate the type, incidence, severity and distress of symptoms of the syndrome and its relationship with socio‐demographic factors.
Data-driven property verification of grey-box systems by bayesian experiment design

A measurement-based statistical verification approach is developed for systems with partly unknown dynamics. These grey-box systems are subject to identification experiments which, new in this contribution, enable accepting or rejecting system properties expressed in a linear-time logic. We employ a Bayesian framework for the computation of a confidence level on the properties and for the design of optimal experiments. Applied to dynamical systems, this work enables data-driven verification of partly-known system dynamics with controllable non-determinism (inputs) and noisy output observations. A numerical case study concerning the safety of a dynamical system is used to elucidate this data-driven and model-based verification technique.
Illness and intelligence are comparatively strong predictors of individual differences in depressive symptoms following middle age

ABSTRACT Objective: We compared the importance of socio-demographic, lifestyle, health, and multiple cognitive measures for predicting individual differences in depressive symptoms in later adulthood. Method: Data came from 6203 community-dwelling older adults (age 41–93 years at study entry) from the United Kingdom. Predictors (36 in total) were assessed up to four times across a period of approximately 12 years. Depressive symptoms were measured with the Geriatric Depression Scale. Statistical methods included multiple imputation (for missing data), random forest analysis (a machine learning approach), and multivariate regression. Results: On average, depressive symptoms increased gradually following middle age and appeared to accelerate in later life. Individual differences in depressive symptoms were most strongly associated with differences in combined symptoms of physical illness (positive relation) and fluid intelligence (negative relation). The strength of association between depressive symptoms and fluid intelligence was unaffected by differences in health status within a subsample of chronically depressed individuals. Conclusion: Joint consideration of general health status and fluid intelligence may facilitate prediction of depressive symptoms severity during later life and may also serve to identify sub-populations of community-dwelling elders at risk for chronic depression.
Rapid desensitization with autologous sweat in cholinergic urticaria.

BACKGROUND The majority of patients with cholinergic urticaria presents with strong hypersensitivity to autologous sweat. Patients with severe cholinergic urticaria are frequently resistant to H(1) antagonists which are used in conventional therapies for various types of urticaria. It has been reported that desensitization using partially purified sweat antigen was effective in a patient with cholinergic urticaria. METHODS The aim of this study is to determine the usefulness of rapid desensitization with autologous sweat in severe cholinergic urticaria, because rapid desensitization has proven to be a quick and effective immunotherapy for allergies to various allergens. Six patients with severe cholinergic urticaria who are resistant to H(1) antagonists and have sweat hypersensitivity were enrolled in a rapid desensitization protocol. RESULTS In all six patients, the responses for skin tests with autologous sweat were attenuated after rapid desensitization with autologous sweat. Two of the three cholinergic urticaria patients showed reduced histamine release with autologous sweat after the rapid desensitization with autologous sweat. Further, the rapid desensitization and subsequent maintenance treatment reduced the symptoms in five of the six patients. CONCLUSIONS This study provides evidence that rapid desensitization with autologous sweat is beneficial for treating cholinergic urticaria patients resistant to conventional therapy who have sweat hypersensitivity.
Surgical treatment of thoracic outlet syndrome: a randomized trial comparing two operations.

OBJECT Various surgical approaches have been proposed for the treatment of thoracic outlet syndrome (TOS). The authors of this study focused on the differences in outcome after supraclavicular neuroplasty of brachial plexus (SNBP [no rib resection]) and transaxillary first rib resection (TFRR) in patients in whom the dominant clinical problem was pain. METHODS Fifty-five patients were randomized to undergo TFRR or SNBP. Patients with an anomalous cervical rib, intrinsic weakness, and primarily vascular findings were excluded from the study. Preoperatively, the following findings were typically observed: provocation of symptoms by certain postures (the so-called spear-throwing position as well as downward tugging of the shoulder) and marked tenderness in the supraclavicular fossa. The intergroup severity of the symptoms was comparable. Eight patients were lost to follow up. There were 24 TFRRs (in two cases the procedure was bilateral) and 25 SNBPs. The mean follow-up interval was 37 months. In both groups pain decreased significantly after surgery. By all measures the TFRR operation conferred superior results. Patients reported significantly less pain (39 +/- 7 compared with 61 +/- 7; score range 0-100 on a visual analog scale), greater percentage of pain relief (52 +/- 8% compared with 30 +/- 7%), and less pain (3.7 +/- 0.4 compared with 5.1 +/- 0.5) on an affective scale (all p < 0.05) in the TFRR and SNBP groups, respectively). In the TFRR group, 75% of patients reported good or excellent outcomes compared with 48% in the SNBP group (p < 0.05). CONCLUSIONS Transaxillary first rib resection provided better relief of symptoms than SNBP. The major compressive element in patients with TOS-associated pain appeared to be the first rib.
Kalman filter used for on line monitoring and predictive maintenance system of aluminium electrolytic capacitors in UPS

The electrolytic capacitor usually has the shortest span of life in the power converter. This paper presents a new low cost implementation of a real time condition monitoring and a predictive maintenance system of an electrolytic capacitor used in Uninterruptible Power Supplies (UPS). It consists of detecting the changes in real time in equivalent series resistance (ESR) and the capacitance C values of the electrolytic capacitors. The proposed method can be used in UPS where waveforms are continuously varying in amplitude, frequency and versus ambient temperature. This method has the merits of using known algorithms and only the existent resources in UPS.
How players value their characters in world of warcraft

Characters in games such as World of Warcraft allow players to act in the game world and to interact with others. Game characters and avatars are a mediated form of self-representation for the player, but some research suggests that players also view characters in other ways that have to do with the kinds of value that the characters provide. To better understand the ways that players value their characters in an online environment, we carried out a semi-structured interview study of twenty World of Warcraft players. From our data we identify ten kinds of value that characters can provide -- including utility, investment, communication, memory, enjoyment, and representations of relationships, as well as value as an opportunity for experience, creativity, sociability, and self-expression. The analytical lens of value provides a new understanding of the ways that players appreciate characters in online multi-user worlds. Our results can help developers understand and enhance an element of multi-player games that contributes greatly to player experience and satisfaction.
Exploration de la dynamique entre les demandes, ressources au travail et la santé psychologique au travail

14 1. Problématique . 16 2. Qu’est-ce que la santé psychologique au travail selon l’approche holistique? 20 3. Quel est le modèle Job Demands-Resources? 22 4. Comment les demandes et ressources au travail influenceraient la santé psychologique au travail? 25 4.1. Qu’est-ce que les demandes et ressources au travail : clarification des définitions? 26 4.2. Comment et pourquoi les demandes influencent la santé psychologique au travail? 28 4.3. Comment les ressources et les demandes interagissent ensemble pour influencer la santé psychologique au travail? 31 4.4. Comment les ressources influencent la santé psychologique au travail indépendamment des demandes? 35 5. Discussion . 37 6. Pistes de recherches futures . 38 Bibliographie. 41
Deep Neural Networks and Hidden Markov Models in i-vector-based Text-Dependent Speaker Verification

Techniques making use of Deep Neural Networks (DNN) have recently been seen to bring large improvements in text-independent speaker recognition. In this paper, we verify that the DNN based methods result in excellent performances in the context of text-dependent speaker veriﬁcation as well. We build our system on the previously introduced HMM based i-vector approach, where phone models are used to obtain frame level alignment in order to collect sufﬁcient statistics for i-vector extraction. For comparison, we experiment with an alternative alignment obtained directly from the output of DNN trained for phone classiﬁcation. We also experiment with DNN based bottleneck features and their combinations with standard cepstral features. Although the i-vector approach is generally considered not suitable for text-dependent speaker veriﬁcation, we show that our HMM based approach combined with bottleneck features provides truly state-of-the-art performance on RSR2015 data.
Imaging in the Diagnosis and Management of Acute Idiopathic Maculopathy

Acute idiopathic maculopathy (AIM), originally termed unilateral AIM, is a rare inflammatory disorder that typically affects young adults (mean age, 32 y; range, 15 to 45 y) and is characterized by acute, severe, unilateral vision loss preceded by a flu-like illness. Men and women are affected equally. Patients generally present with visual acuity of r20/200 and complain of central metamorphopsia and/or scotoma formation that is attributable to an exudative macular detachment. There may also be hypopigmentation of the retinal pigment epithelium, which may simulate the appearance of choroidal neovascularization (CNV) (Fig. 1). Papillitis, a few vitreous cells, subretinal exudation, and bilaterality have also been observed in AIM, whereas eccentric macular lesions have been noted in cases with milder vision loss (20/60 to 20/100). Most cases resolve spontaneously with near-complete recovery of vision (20/25 or better) over a period of 3 weeks to 6 months. After resolution of the macular detachment, a ‘‘bull’s-eye’’ pattern composed of retinal pigment epithelial (RPE) hyperpigmentation surrounded by hypopigmented atrophic changes develops at the site of the antecedent neurosensory detachment (Fig. 2). To date, there has been only 1 reported case with recurrent episodes of AIM. Rarely, secondary CNV has occurred after resolution of AIM. The authors have seen a case of secondary CNV after AIM that responded well to intravitreal anti-vascular endothelial growth factor therapy. The flu-like illness that precedes AIM suggests a viral cause. The coxsackie virus has been implicated in the pathogenesis of AIM,
Changes in desmoglein 1 expression and subcellular localization in cultured keratinocytes subjected to anti‐desmoglein 1 pemphigus autoimmunity

The complexity of pemphigus acantholysis together with the weak expression of desmoglein 1 (Dsg1) in cultured keratinocytes have made the study on the pathogenic action of anti‐Dsg1 antibodies quite difficult. The pathophysiology of the acantholytic phenomenon could depend on the reduction of Dsg1 adhesion function occurring after its massive internalization or decrease of its synthesis. Here, we have investigated this hypothesis by using sera of patients having antibodies against Dsg1 or monoclonal anti‐Dsg1 antibodies to simulate pemphigus autoimmunity in Dsg1‐rich keratinocytes. Similar to pemphigus foliaceus (PF) and vulgaris (PV) sera, monoclonal anti‐Dsg1 antibodies induced transient internalization of Dsg1 and reduced the adhesion strength among keratinocytes. However, binding of IgG to Dsg1 did not determine its early depletion from the adhesion complexes but reduced the amount of Dsg1 found in the Triton X‐100 soluble pool of proteins. Taken together, our results represent the first demonstration that anti‐Dsg1 antibodies induce similar alterations on the subcellular distribution of Dsg1 irrespective of the disease where they come from. Furthermore, the present study provides insight into the mechanisms underlying epithelial blistering observed in the skin type of pemphigus. J. Cell. Physiol. 210: 411–416, 2007. © 2006 Wiley‐Liss, Inc.
Reduction of intrachannel nonlinear distortion in 40-Gb/s-based WDM transmission over standard fiber

Intrachannel cross-phase modulation and four-wave mixing in high-bit-rate WDM transmission systems employing standard single-mode fiber are investigated. The effects of imperfect third-order dispersion compensation are included in the study and analytical expressions giving optimum values of dispersion precompensation minimizing the distortion due to the intrachannel nonlinear effects are derived.
Voice source correlates of prosodic features in american English: a pilot study

In this paper, we examine the dependencies of voice source parameters F0(fundamental frequency), Ee(maximal glottal flow change), RK(glottal symmetry/skew), LIN (value related to source spectral tilt) and H∗ 1 −H∗ 2 (difference of formant-corrected magnitudes of the first two source spectral harmonics) on prosodic features such as pitch accents, stress, and sentence type and the interdependencies of some of these measures. A small, carefully designed corpus containing a sentence in different prosodic configurations was used in this study. Statistical analysis was performed using two-way ANOVAs to test for the voice source parameter dependencies. Results show that F0 is positively correlated with Ee and LIN , and negatively correlated with H∗ 1−H 2 . Stressed syllables showed lower values of RK and H∗ 1−H 2 compared to stressless syllables. The effect of pitch accent can be seen as a combination of its F0, and stress. Phrase-final syllables for interrogative sentences yielded a higher F0 and lower RK and H∗ 1 −H∗ 2 compared to declarative sentences. It was found that it is important to differentiate between tones when analyzing prosodic features that involve tones, such as pitch accent and probably boundary.
Relationship of cellulosomal and noncellulosomal xylanases of Clostridium thermocellum to cellulose-degrading enzymes

Xylanase activity of Clostridium thermocellum, an anaerobic thermophilic cellulolytic bacterium, was characterized. The activity was localized both in the cellulosome (the principal multienzyme, cellulose-solubilizing protein complex) and in noncellulosomal fractions. Each of these fractions contained at least four major polypeptide bands which contributed to the xylanolytic activity. In both cases, pH and temperature optima, product pattern, and other features of the xylanase activity were almost identical. The main difference was in the average molecular weights of the respective polypeptides which appeared responsible for the activity. In the noncellulosomal fraction, xylanases with Mrs ranging from 30,000 to 65,000 were detected. Distinct from these were the cellulosomal xylanases, which exhibited much larger Mrs (up to 170,000). The cellulosome-associated xylanases corresponded to known cellulosomal subunits, some of which also exhibited endoglucanase activity, and others which coincided with subunits which appeared to express exoglucanaselike activity. In contrast, the noncellulosomal xylanases hydrolyzed xylan exclusively. beta-Glucosidase and beta-xylosidase activities were shown to be the action of different enzymes; both were associated exclusively with the cell and were not components of the cellulosome. Despite the lack of growth on and utilization of xylan or its degradation products, C. thermocellum produces a highly developed xylanolytic apparatus which is interlinked with its cellulase system.
Aβ Oligomer-Mediated Long-Term Potentiation Impairment Involves Protein Phosphatase 1-Dependent Mechanisms

Amyloid β (Aβ) oligomers are derived from proteolytic cleavage of amyloid precursor protein (APP) and can impair memory and hippocampal long-term potentiation (LTP) in vivo and in vitro. They are recognized as the primary neurotoxic agents in Alzheimer's disease. The mechanisms underlying such toxicity on synaptic functions are complex and not fully understood. Here, we provide the first evidence that these mechanisms involve protein phosphatase 1 (PP1). Using a novel transgenic mouse model expressing human APP with the Swedish and Arctic mutations that render Aβ more prone to form oligomers (arcAβ mice), we show that the LTP impairment induced by Aβ oligomers can be fully reversed by PP1 inhibition in vitro. We further demonstrate that the genetic inhibition of endogenous PP1 in vivo confers resistance to Aβ oligomer-mediated toxicity and preserves LTP. Overall, these results reveal that PP1 is a key player in the mechanisms of AD pathology.
Indices for Continuity of Care: A Systematic Review of the Literature

This article systematically reviews published literature on different continuity of care (COC) indices that assess the physician-patient relationship and the applicability of such indices to pediatric and chronic-disease patient populations. Frequency and visit type may vary for pediatric and chronically ill patients versus healthy adult patients. Two investigators independently examined 5,070 candidate articles and identified 246 articles related to COC. Forty-four articles were identified that include 32 different indices used to measure COC. Indices were classified into those that calculated COC primarily based on duration of provider relationship (n = 2), density of visits (n = 17), dispersion of providers (n = 8), sequence of providers (n = 1), or subjective estimates (n = 4). The diversity of COC indices reflect differences in how this measure is conceptualized. No index takes into account the visit type. A unique index that reflects continuity in the physicianpatient relationship for pediatric and chronic disease populations is needed.
Development of a Method of Calculating the Melting Characteristics of OPGW Strands Due to DC Arc Simulating Lightning Strike

Some strands of composite fiber-optic ground wire (OPGW) are sometimes melted and broken by high-energy lightning strikes. DC arc tests simulating lightning strikes have been performed to obtain the melting and breaking characteristics of OPGW strands. The tests have to be performed under many conditions concerning the arc (e.g., current, duration, polarity, gap length) and the OPGW (e.g., size, type, and number of strands) to clarify the melting and breaking characteristics of the strands. In this paper, the calculations regarding the melting characteristics of strands are performed considering the transferred heat and its area from the arc to the strands under the aforementioned conditions. The melting characteristics of strands are calculated with an arc current of 1-100 kA considering the measured current of actual lightning. The calculation results of the strand melting duration depending on arc current show good agreement with the experimental values obtained in dc arc tests.
Associations between social anxiety disorders and the social aspects of young people's Internet and mobile phone use

This thesis investigates young people's use of the Internet and mobile phones, and focuses especially on associations between use of these technologies for communication purposes and social anxiety. First, two surveys are reported which examine the broad characteristics of young people’s Internet and mobile phone use. The first of these was conducted on paper and provides a general description of these activities amongst young people in the Teesside area of England. The second survey was conducted online with a population from a wider area and supports the paper survey. Together, the surveys indicate that there may be a small bias towards male use of and competence with the Internet. There may also be a small bias towards female use of mobile phones. Results concerning non-use of the Internet and mobile phones are also discussed. Reports of the surveys are followed by descriptions of a questionnaire study, also conducted in the Teesside area of England, which indicates that associations between the psychological conditions social anxiety and social phobia and use of the Internet and mobile phones, generally, and for communication purposes, are minimal. (However, small but significant associations are discussed). Finally, was conducted using Grounded Theory, is described. This reveals that that control over social interactions, sometimes in relation to transient, or situational, social anxiety, might be one important reason why young people like to use text-based Internet and mobile phone communication media to interact. It is concluded that whilst social anxiety as a psychological characteristic or trait may not be strongly related to young people s use of the Internet and mobile phones for communication purposes, young people may nevertheless sometimes use these technologies to manage situational social anxiety.