Miracle-dz/UniFAR-FTUs huggingface dataset:
Appraisal determinants of discrete emotions.

Abstract A theory specifying how appraisals of a situation determine one's emotional responses (Roseman, 1979) was subjected to an experimental test. According to the theory, particular combinations of 5 appraisals determine which of 13 qualitatively different emotions will be experienced in any given situation. The appraisals are: motivational state (rewarding/punishing), situational state (presendabsent), probability (certaiduncertain), legitimacy (positivehegative outcome deserved), and causal agency (circumstanced other person/self). The emotions whose occurrence they determine are joy, relief, hope, liking (“warmth-friendliness”), pride, distress, sorrow, fear, frustration, disliking (“coolness-unfriendliness”), anger, regret, and guilt. In the experiment, 120 college students read brief stories in which these appraisals were manipulated, and rated the intensities of various emotions felt by story protagonists. Results showed that each appraisal had a significant effect upon emotions, and that the pa.
THE CONSEQUENCES OF DIVORCE FOR ADULTS AND CHILDREN: AN UPDATE

The divorce rate has increased in the United States and most European countries since the 1960s. Public and scientific concern about the consequences of divorce for adults and children has generated a large research literature. Most studies find that divorced adults experience more mental and physical health problems than do married adults. Similarly, most studies find that children with divorced parents experience more mental and physical health problems than do children with continuously married parents. Available research suggests that these associations are partly spurious (due to selection effects) and partly due to the stress associated with marital disruption. People's reactions to divorce are highly variable, with the speed and degree of adjustment depending on a variety of resources and post-divorce circumstances. In the United States, several types of court- and community-based programs appear to facilitate parents' and children's adjustment to divorce.
Revisiting the Diversity of Gentrification: Neighbourhood Renewal Processes in Brussels and Montreal

This article provides a comparative analysis of neighbourhood renewal processes in Brussels and Montreal based on a typology of such processes wherein gentrification is precisely delimited. In this way, it seeks to break with the extensive use of a chaotic conception of gentrification referring to the classic stage model when dealing with the geographical diversity of neighbourhood renewal, within or between cities. In both Brussels and Montreal, the gentrification concept only adequatly describes the upward movement of very restricted parts of the inner city, while neighbourhood renewal in general more typically comprises marginal gentrification, upgrading and incumbent upgrading. Evidence drawn from the case studies suggests that each of these processes is relevant on its own-i.e. linked to a particular set of causal factors-rather than composing basically transitional states within a step-by-step progression towards a common gentrified fate. Empirical results achieved in Brussels and Montreal suggest that a typology such as the one implemented in this article could be used further in wider research aimed at building a geography of neighbourhood renewal throughout Western cities.
Endothelial cell motility, coordination and pattern formation during vasculogenesis

How vascular networks assemble is a fundamental problem of developmental biology that also has medical importance. To explain the organizational principles behind vascular patterning, we must understand how can tissue level structures be controlled through cell behavior patterns like motility and adhesion that, in turn, are determined by biochemical signal transduction processes? We discuss the various ideas that have been proposed as mechanisms for vascular network assembly: cell motility guided by extracellular matrix alignment (contact guidance), chemotaxis guided by paracrine and autocrine morphogens, and multicellular sprouting guided by cell–cell contacts. All of these processes yield emergent patterns, thus endothelial cells can form an interconnected structure autonomously, without guidance from an external pre‐pattern. WIREs Syst Biol Med 2013, 5:587–602. doi: 10.1002/wsbm.1233
Visual Selective Behavior Can Be Triggered by a Feed-Forward Process

The ventral visual pathway implements object recognition and categorization in a hierarchy of processing areas with neuronal selectivities of increasing complexity. The presence of massive feedback connections within this hierarchy raises the possibility that normal visual processing relies on the use of computational loops. It is not known, however, whether object recognition can be performed at all without such loops (i.e., in a purely feed-forward mode). By analyzing the time course of reaction times in a masked natural scene categorization paradigm, we show that the human visual system can generate selective motor responses based on a single feed-forward pass. We confirm these results using a more constrained letter discrimination task, in which the rapid succession of a target and mask is actually perceived as a distractor. We show that a masked stimulus presented for only 26 msecand often not consciously perceivedcan fully determine the earliest selective motor responses: The neural representations of the stimulus and mask are thus kept separated during a short period corresponding to the feed-forward sweep. Therefore, feedback loops do not appear to be mandatory for visual processing. Rather, we found that such loops allow the masked stimulus to reverberate in the visual system and affect behavior for nearly 150 msec after the feed-forward sweep.
Moving into practice: transitions from further education trainee teacher to lecturer

The current paper draws on data derived from a small‐scale ongoing longitudinal study of further education trainee teachers. It examines their experiences during and after the completion of their training. The study was conducted at a university in the English Midlands and sets trainees' experiences within the socio‐economic and policy context. This paper addresses the experiences of six respondents, exploring their trajectory into the sector, orientations towards pedagogic relations and enacted professionality. The paper concludes by suggesting that trainees' educational commitment to the tenets of social justice need to be accompanied by an expansive and politicised understanding of practice.
Sevoflurane/remifentanil versus propofol/remifentanil for electroconvulsive therapy: Comparison of seizure duration and haemodynamic responses

Objective To compare the anaesthetic and convulsive effects of sevoflurane/remifentanil versus propofol/remifentanil combination in electroconvulsive therapy (ECT). Methods In this prospective, randomized double-blind study, patients diagnosed with treatment-resistant depression were included for ECT. Prior to treatment, 1 µg/kg remifentanil was intravenously administered to all patients, followed by anaesthetic induction with either 0.5 mg/kg propofol or 8% sevoflurane. Following muscular paralysis with succinylcholine and hypnosis, bitemporal ECT was applied. Vital signs, depth of sedation, recovery parameters, motor and electroencephalography (EEG) convulsion activity and postictal suppression index scores were recorded. Results A total of 120 sessions of ECT were administered to 12 patients. Heart rate was higher in the sevoflurane group than the propofol group. Compared with the sevoflurane group, bispectral index level was lower in the propofol group during the induction period and higher during the recovery period. Anaesthetic induction and recovery times were lower, and average motor and EEG convulsion activity was longer, in the propofol group than in the sevoflurane group. Conclusion Propofol/remifentanil is more successful compared with sevoflurane/remifentanil in anaesthesia management during ECT since it provides quick induction and recovery, longer seizure activity and stable haemodynamics.
Prague as the centre of Russian educational emigration: Czechoslovakia’s educational policy for Russian emigrants (1918–1938)

This article looks at the role played by the Czechoslovakian Republic in the establishment and maintenance of the “Russian education system in exile” in Europe during the 1920s and 1930s. No other country supported the educational activities of the Russian emigrants as generously as Czechoslovakia. Thanks to this extensive and targeted support, a well‐developed “Russian education system” came into being in Czechoslovakia, and Prague became the centre of Russian educational emigration in Europe. Czechoslovakia’s support for the Russian emigrants had not only humanitarian reasons, but was to a large extent motivated by political and economic interests.
Mrk 421 active state in 2008: the MAGIC view, simultaneous multi-wavelength observations and SSC model constrained

The blazar Markarian 421 is one of the brightest TeV gamma-ray sources of the northern sky. From December 2007 until June 2008 it was intensively observed in the very high energy (VHE, E > 100 GeV) band by the single-dish Major Atmospheric Gamma-ray Imaging Cherenkov telescope (MAGIC-I). Aims. We aimed to measure the physical parameters of the emitting region of the blazar jet during active states. Methods. We performed a dense monitoring of the source in VHE with MAGIC-I, and also collected complementary data in soft X-rays and optical-UV bands; then, we modeled the spectral energy distributions (SED) derived from simultaneous multi-wavelength data within the synchrotron self-Compton (SSC) framework. Results. The source showed intense and prolonged. -ray activity during the whole period, with integral fluxes (E > 200 GeV) seldom below the level of the Crab Nebula, and up to 3.6 times this value. Eight datasets of simultaneous optical-UV (KVA, Swift/UVOT), soft X-ray (Swift/XRT) and MAGIC-I VHE data were obtained during different outburst phases. The data constrain the physical parameters of the jet, once the spectral energy distributions obtained are interpreted within the framework of a single-zone SSC leptonic model. Conclusions. The main outcome of the study is that within the homogeneous model high Doppler factors (40 <= delta <= 80) are needed to reproduce the observed SED; but this model cannot explain the observed short time-scale variability, while it can be argued that inhomogeneous models could allow for less extreme Doppler factors, more intense magnetic fields and shorter electron cooling times compatible with hour or sub-hour scale variability.
Epstein-Barr Virus as a Trigger of Autoimmune Liver Diseases

The pathogenesis of autoimmune diseases includes a combination of genetic factors and environmental exposures including infectious agents. Infectious triggers are commonly indicated as being involved in the induction of autoimmune disease, with Epstein-Barr virus (EBV) being implicated in several autoimmune disorders. EBV is appealing in the pathogenesis of autoimmune disease, due to its high prevalence worldwide, its persistency throughout life in the host's B lymphocytes, and its ability to alter the host's immune response and to inhibit apoptosis. However, the evidence in support of EBV in the pathogenesis varies among diseases. Autoimmune liver diseases (AiLDs), including autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), have a potential causative link with EBV. The data surrounding EBV and AiLD are scarce. The lack of evidence surrounding EBV in AiLD may also be reflective of the rarity of these conditions. EBV infection has also been linked to other autoimmune conditions, which are often found to be concomitant with AiLD. This paper will critically examine the literature surrounding the link between EBV infection and AiLD development. The current evidence is far from being conclusive of the theory of a link between EBV and AiLD.
Health, Locus of Control, Values, and the Behavior of Family and Friends: An Integrated Approach to Understanding Preventive Health Behavior

This study examines the mediating role of health locus of control beliefs in the relationship of relevant psychological variables to preventive health behavior. In specific, two hypothesis are tested: (1) that health locus of control mediates the relationship between positive health values and preventive health behavior and (2) that health locus of control mediates the negative effects of the social environment on preventive health behavior. It was found that it is the respondent who both values health and has an internal locus of control who is most likely to engage in preventive health behavior. Conversely, respondents with an external locus of control who are exposed to associates with poor health behavior patterns exhibit lower levels of preventive health behavior than internals or those exposed to positive health behavior. Finally, although the respondents' close assosiates are the strongest influence on their health lifestyle, the respondents are virtually unaware of this influence.
The Effect of Woman Leadership Style and Organizational Culture on Locus of Control, Work Achievement, and Work Satisfaction of Employee

Research begins from May to August of 2011 at The Governor Office of South Sulawesi Province. The objective of research is to understand and to analyze the direct and indirect effect of woman leadership style and organizational culture on locus of control, work achievement, and work satisfaction of employee. Research type is explanatory with survey method. The respondent is the work unit under the leadership of woman. Sampling technique is minimized sample method which results in 135 respondents. Data analysis method is Structure Equation Modeling (SEM). Result of analysis indicates that women leadership style is having positive and significant effect on locus of control, work achievement, and work satisfaction of employee.
Clinical Utility of LC3 and p62 Immunohistochemistry in Diagnosis of Drug-Induced Autophagic Vacuolar Myopathies: A Case-Control Study

Background Some patients treated with chloroquine, hydroxychloroquine, or colchicine develop autophagic vacuolar myopathy, the diagnosis of which currently requires electron microscopy. The goal of the current study was to develop an immunohistochemical diagnostic marker for this pathologic entity. Methodology Microtubule-associated protein light chain 3 (LC3) has emerged as a robust marker of autophagosomes. LC3 binds p62/SQSTM1, an adapter protein that is selectively degraded via autophagy. In this study, we evaluated the utility of immunohistochemical stains for LC3 and p62 as diagnostic markers of drug-induced autophagic vacuolar myopathy. The staining was performed on archival muscle biopsy material, with subject assignment to normal control, drug-treated control, and autophagic myopathy groups based on history of drug use and morphologic criteria. Principal Findings In all drug-treated subjects, but not in normal controls, LC3 and p62 showed punctate staining characteristic of autophagosome buildup. In the autophagic myopathy subjects, puncta were coarser and tended to coalesce into linear structures aligned with the longitudinal axis of the fiber, often in the vicinity of vacuoles. The percentage of LC3- and p62-positive fibers was significantly higher in the autophagic myopathy group compared to either the normal control (p<0.001) or the drug-treated control group (p<0.05). With the diagnostic threshold set between 8% and 15% positive fibers (depending on the desired level of sensitivity and specificity), immunohistochemical staining for either LC3 or p62 could be used to identify subjects with autophagic vacuolar myopathy within the drug-treated subject group (p≤0.001). Significance Immunohistochemistry for LC3 and p62 can facilitate tissue-based diagnosis of drug-induced autophagic vacuolar myopathies. By limiting the need for electron microscopy (a time consuming and costly technique with high specificity, but low sensitivity), clinical use of these markers will improve the speed and accuracy of diagnosis, resulting in significantly improved clinical care.
Evidence of ongoing immune reconstitution in subjects with sustained viral suppression following 6 years of lopinavir-ritonavir treatment.

BACKGROUND We evaluated the immunologic impact of highly active antiretroviral therapy in subjects who maintained human immunodeficiency virus type 1 (HIV-1) suppression through 6 years of receiving a lopinavir-ritonavir-based regimen. METHODS A total of 100 antiretroviral-naive subjects with any CD4+ T cell count initiated therapy with lopinavir-ritonavir, stavudine, and lamivudine. Sixty-three subjects who remained in the study for 6 years were assessed. Laboratory measurements included plasma HIV-1 RNA levels, multiparameter flow cytometry of immune cells, and markers of maturation and activation. RESULTS After 6 years, 62 of 63 subjects had plasma HIV-1 RNA levels <50 copies/mL. The mean increase in CD4+ T cell count was 528 cells/microL (P<.001), and 81% of subjects had CD4+ T cell counts >500 cells/microL, compared with 21% of subjects at baseline. The mean ratio of CD4+ T cell count to CD8+ T cell count increased from 0.38 at baseline to 0.96 at year 6 (P<.001). The percentage of subjects with cell counts below the lower limit of normal at year 6, compared with at baseline, was significantly decreased for total T cells, B cells, and natural killer cells. At year 6, the median CD4+ T cell activation level was 3.4%, and the median CD8+ T cell activation level was 5.8%. CONCLUSIONS The receipt of a lopinavir-ritonavir-based regimen resulted in ongoing immune reconstitution through 6 years of therapy in a cohort of HIV-1-infected, antiretroviral-naive subjects with suppressed HIV-1 RNA levels. Normalization of activation marker expression on CD4+ and CD8+ T cell subsets was demonstrated.
Treeline dynamics with climate change at the central Nepal Himalaya

Abstract. Treeline shifting in tandem with climate change has widely been reported from various parts of the world. In Nepal, several impacts of climate change on the physical environment have been observed, but study on the biological impacts is lacking. This dendrochronological study was carried out at the treeline in the high mountain slope of Kalchuman Lake (3750–4003 m a.s.l.) area of Manaslu Conservation Area in the central Nepal Himalaya to explore the impact of climate change on the treeline dynamic. Two belt transect plots (size: 20 m wide, > 250 m long) were laid which included treeline as well as tree species limit. Ecological mapping of all individuals of dominant trees Abies spectabilis and Betula utilis was done and their tree cores were collected. Stand character and age distribution revealed an occurrence of more matured B. utilis (max. age 198 years) compared to A. spectabilis (max. age 160 years). A. spectabilis contained an overwhelmingly high population (89%) of younger plants (
Dynamic Entity Representation with Max-pooling Improves Machine Reading

We propose a novel neural network model for machine reading, DER Network, which explicitly implements a reader building dynamic meaning representations for entities by gathering and accumulating information around the entities as it reads a document. Evaluated on a recent large scale dataset (Hermann et al., 2015), our model exhibits better results than previous research, and we find that max-pooling is suited for modeling the accumulation of information on entities. Further analysis suggests that our model can put together multiple pieces of information encoded in different sentences to answer complicated questions. Our code for the model is available at https://github. com/soskek/der-network
Subthalamic nucleus lesions alter basal and dopamine agonist stimulated electrophysiological output from the rat basal ganglia

The subthalamic nucleus (STN) is an important link in the “indirect” striatal efferent pathway. To assess its role on basal ganglia output via the substantia nigra pars reticulata (SNr), we monitored the single unit activities of SNr neurons in chloral hydrate‐anesthetized rats 5–8 days after bilateral kainic acid lesions (0.75 μg/0.3 μl/side) of the STN. Consistent with loss of an excitatory input, the average basal firing rate of SNr neurons was significantly reduced in STN‐lesioned animals. Moreover, the lesions modified the responses of SNr neurons to individual and concurrent stimulation of striatal D1 and D2 receptors. Bilateral striatal infusions of the D1/D2 agonist apomorphine (10 μg/μl/side) into the ventral‐lateral striatum (VLS) were previously shown to cause significant increases in SNr cell firing (to 133% of baseline) in normal rats. However, in STN‐lesioned rats, identical infusions caused no overall change in SNr activity (mean, 103% of basal rates). Conversely, selective stimulation of striatal D2 receptors by bilateral co‐infusion of the D2 agonist quinpirole and the D1 antagonist SCH 23390 that previously caused little change in SNr firing in normal rats significantly inhibited their firing in STN‐lesioned rats. Finally, the modest excitatory responses of SNr neurons to selective stimulation of striatal D1 receptors by co‐infusions of SKF 82958 with the D2 antagonist YM09151‐2 were not altered by lesions of the STN. These results implicate the STN as a mediator of excitatory response of SNr neurons to D2, and mixed D1/D2, dopamine receptor agonists in normal rats, and challenge conventional views on the role of the STN and the “indirect” pathway in regulating dopamine‐stimulated output from the SNr. Synapse 54:119–128, 2004. © 2004 Wiley‐Liss, Inc.
Correlations between the Stanford-Binet: Fourth Edition and the WISC—R with a learning disabled population.

The Fourth Edition of the Stanford-Binet and the WISC-R were compared as instruments for assessing the intellectual strengths and weaknesses of students classified as learning disabled in the primary and secondary grades. Results found only a 3.28-point difference (p≥.0001) between the S-B Composite score and the WISC-R Full Scale score. Correlations between the four broad areas of the S-B and the three scales of the WISC-R ranged from . 494 (S-B Abstract/Visual Reasoning with WISC-R Verbal) to . 920 (S-B Composite with WISC-R Full Scale). All correlations were found to be significant. Implications of the research findings were discussed.
Developments of the Price equation and natural selection under uncertainty

Many approaches to the study of adaptation, following Darwin, centre on the number of offspring of individuals. Population genetics theory makes clear that predicting gene frequency changes requires more detailed knowledge, for example of linkage and linkage disequilibrium and mating systems. Because gene frequency changes underly adaptation, this can lead to a suspicion that approaches ignoring these sophistications are approximate or tentative or wrong. Stochastic environments and sexual selection are two topics in which there are widespread views that focusing on number of offspring of individuals is not enough, and that proper treatments require the introduction of further details, namely variability in offspring number and linkage disequilibrium, respectively. However, the bulk of empirical research on adaptation and a great deal of theoretical work continue to employ these approaches. Here, a new theoretical development arising from the Price equation provides a formal justification in very general circumstances for focusing on the arithmetic average of the relative number of offspring of individuals.