Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Condensed Tannins in Mao (Antidesma thwaitesianum Muell. Arg.) Seed Meal on Rumen Fermentation Characteristics and Nitrogen Utilization in Goats

Mao seed is a by-product of the wine and juice industry, which could be used in animal nutrition. The current study was designed to determine the effect of supplementation of mao (Antidesma thwaitesianum Muell. Arg.) seed meal (MOSM) containing condensed tannins (CT) on rumen fermentation, nitrogen (N) utilization and microbial protein synthesis in goats. Four crossbred (Thai Native×Anglo Nubian) goats with initial body weight (BW) 20±2 kg were randomly assigned to a 4×4 Latin square design. The four dietary treatments were MOSM supplementation at 0%, 0.8%, 1.6%, and 2.4% of total dry matter (DM) intake, respectively. During the experimental periods, all goats were fed a diet containing roughage to concentrate ratio of 60:40 at 3.0% BW/d and pangola grass hay was used as a roughage source. Results showed that supplementation with MOSM did not affect feed intake, nutrient intakes and apparent nutrient digestibility (p>0.05). In addition, ruminal pH and ammonia nitrogen (NH3-N) were not influenced by MOSM supplementation, whilst blood urea nitrogen was decreased quadraticly (p<0.05) in goats supplemented with MOSM at 2.4% of total DM intake. Propionate was increased linearly with MOSM supplementation, whereas acetate and butyrate were remained the same. Moreover, estimated ruminal methane (CH4) was decreased linearly (p<0.05) when goats were fed with MOSM at 1.6% and 2.4% of total DM intake. Numbers of bacteria and protozoa were similar among treatments (p>0.05). There were linear decreases in urinary N (p<0.01) and total N excretion (p<0.01) by MOSM supplementation. Furthermore, N retention was increased linearly (p<0.05) when goats were fed with MOSM supplementation at 1.6% and 2.4% of total DM intake. Microbial protein synthesis were not significantly different among treatments (p>0.05). From the current study, it can be concluded that supplementation of MOSM at 1.6% to 2.4% of total DM intake can be used to modify ruminal fermentation, especially propionate and N utilization in goats, without affecting the nutrient digestibility, microbial populations and microbial protein synthesis.
Multidimensional Transfer Functions for Interactive Volume Rendering

Most direct volume renderings produced today employ 1D transfer functions which assign color and opacity to the volume based solely on the single scalar quantity which comprises the data set. Though they have not received widespread attention, multi-dimensional transfer functions are a very effective way to extract materials and their boundaries for both scalar and multivariate data. However, identifying good transfer functions is difficult enough in 1D, let alone 2D or 3D. This paper demonstrates an important class of 3D transfer functions for scalar data, and describes the application of multi-dimensional transfer functions to multivariate data. We present a set of direct manipulation widgets that make specifying such transfer functions intuitive and convenient. We also describe how to use modern graphics hardware to both interactively render with multidimensional transfer functions and to provide interactive shadows for volumes. The transfer functions, widgets and hardware combine to form a powerful system for interactive volume exploration.
A Flow-Based Explanation for Return Predictability

This paper proposes and tests an investment-flow based explanation for three empirical findings on return predictability – the persistence of mutual fund performance, the “smart money¶ effect, and stock price momentum. Since mutual fund managers generally scale up or down their existing positions in response to investment flows, and the portfolios of funds receiving capital generally differ from those that lose capital, investment flows to mutual funds can cause significant demand shocks in individual stocks. Moreover, given that mutual fund ows are largely predictable from past fund performance and past flows, this paper further establishes that flow-induced price pressure is predictable. Finally, this paper shows that such flow-based return predictability can fully account for mutual fund performance persistence and the “smart money¶ effect and can partially explain stock price momentum.
Models of Parasite Virulence

Several evolutionary processes influence virulence, the amount of damage a parasite causes to its host. For example, parasites are favored to exploit their hosts prudently to prolong infection and avoid killing the host. Parasites also need to use some host resources to reproduce and transmit infections to new hosts. Thus parasites face a tradeoff between prudent exploitation and rapid reproduction -a life history tradeoff between logevity and fecundity. Other tradeoffs among components of parasite fitness also influence virulence. For example, competition among parasite genotypes favors rapid growth to achieve greater relative success within the host. Rapid growth may, however, lower the total productivity of the local group by overexploiting the host, which is a potentially renewable food suply. This is a problem of kin selection and group selection. I summarize models of parasite virulence with the theoretical tools of life history analysis, kin selection, and epidemiology. I then apply the theory to recent empirical studies and models of virulence. These applications, to nematodes, to the extreme virulence of hospital epidemics, and to bacterial meningitis, show the power of simple life history theory to highlight interesting questions and to provide a rich array of hypotheses. These examples also show the kinds of conceptual mistakes that commonly arise when only a few components of parasite fitness are analysed in isolation. The last part of the article connects standard models of parasite virulence to diverse topics, such as the virulence of bacterial plasmids, the evolution of genomes, and the processes that influence conflict and cooperation among the earliest replicators near the origin of life.
Guaranteed Packet Delays with Network Coding

In the context of networks providing QoS guarantees, the end-to-end delay experienced by a packet is an important parameter. In this paper, we show that network coding can be used to decrease worst case end-to-end bounds when compared to a classical routing strategy. This result can be explained by the fact that network coding can cope with congestion better that classical routing due to its property to process simultaneously packets from different flows. In this paper, two network coding strategies, applied to networks providing QoS guarantees, are presented. We present an evaluation of worst case delays both in routing and coding approaches with network calculus tools. An interesting result is that network coding can improve these guaranteed end-to-end bounds even in network topologies where the throughput is not improved.
Calcium Orthophosphates in Nature, Biology and Medicine

The present overview is intended to point the readers’ attention to the important subject of calcium orthophosphates. These materials are of the special significance because they represent the inorganic part of major normal (bones, teeth and dear antlers) and pathological (i.e. those appearing due to various diseases) calcified tissues of mammals. Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium ortho-phosphates. For example, self-setting hydraulic cements made of calcium orthophosphates are helpful in bone repair, while titanium substitutes covered by a surface layer of calcium orthophosphates are used for hip joint endoprostheses and as tooth substitutes. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. In addition, technical grade calcium orthophosphates are very popular mineral fertilizers. Thus ere calcium orthophosphates are of great significance for humankind and, in this paper, an overview on the current knowledge on this subject is provided.
PROPERTIES OF MOTOR UNITS IN A HETEROGENEOUS PALE MUSCLE (M. GASTROCNEMIUS) OF THE CAT.

THE PRECEDING PAPER (7) is an account of motor units in the soleus muscle of the cat, which is an example of the red or slow variety of skeletal muscles. For comparison with it, we present here the results of a similar study on the medial gastrocnemius (MG), a pale or fast muscle. The two muscles are separate heads of the triceps surae, which is an extensor of the foot. Although they are closely related anatomically they differ strikingly in their microscopic appearance and in their contractile properties. Ranvier (8) correlated the pale color of muscles such as the MG with their phasic mechanical properties (fast contraction, higher fusion rates, easy fatigability), but later authors have cautioned against such simplification. For many years it has been known that pale muscles consist of a mixture of dark and pale fibers. Recent studies (9) show that they contain three kinds of fibers which differ in their mitochondrial enzymes and in their appearance under the electron microscope. We shall attempt to correlate these observations with the differing properties of individual motor units. We shall also try to reconcile our findings with the striking differences in functional capacity of the soleus and MG, notably their relative speed and power.
Collaborative robots for indoor environment exploration

The design and implementation of a robot team consisting of three homogeneous mobile robots and an external server is presented. The main goal of the robot team is the updating of a map or representation of an indoor environment. A scheme for collective exploration was defined. This scheme enables robots to navigate and self-locate within an indoor environment, communicate to each other, create local maps of their environment to be merged into a global map, and coordinate individual actions in order to explore autonomously the environment. Finally, the performance of the robot team was evaluated in various environmental conditions.
Stochastic synthesis of earthquake catalogs

A model of earthquake occurrence is proposed that is based on results of statistical studies of earthquake catalogs. We assume that each earthquake generates additional a probability that depends on time as t−(1+θ). This assumption together with one regarding the independence of branching events on adjacent branches of the event ‘tree,’ is sufficient to permit the generation of complete catalogs of earthquakes that have the same time-magnitude statistical properties as real earthquake catalogs. If θ is about 0.5, the process generates sequences that have statistical properties similar to those for shallow earthquakes: many well-known relations are reproduced including the magnitude-frequency law, Omori's law of the rate of aftershock and foreshock occurrence, the duration of a recorded seismic event versus its magnitude, the self-similarity or lack of scale of rate of earthquake occurrence in different magnitude ranges, etc. A value of θ closer to 0.8 or 0.9 seems to simulate the statistical properties of intermediate and deep shocks. A formula for seismic risk prediction is proposed,and the implications of the model for risk evaluation are outlined. The possibilities of the determination of long-term risk from real or synthetic catalogs that have the property of self-similarity are dim.
Bargaining order and delays in multilateral bargaining with asymmetric sellers

In a multilateral bargaining problem with one buyer and two heterogeneous sellers owning perfectly complementary units, we find that there exists an equilibrium which leads to inefficient delays when the buyer negotiates with the higher-valuation seller first and where players are extremely impatient. We also find that the buyer prefers to negotiate with the lower-valuation seller first, except in an equilibrium where both the buyer and the lower-valuation seller choose to play strategies that lead negotiations between them to hold out.
Nkx2.7 and Nkx2.5 Function Redundantly and Are Required for Cardiac Morphogenesis of Zebrafish Embryos

Background Nkx2.7 is the tinman-related gene, as well as orthologs of Nkx2.5 and Nkx-2.3. Nkx2.7 and Nkx2.5 express in zebrafish heart fields of lateral plate mesoderm. The temporal and spatial expression patterns of Nkx2.7 are similar to those of Nkx2.5, but their functions during cardiogenesis remain unclear. Methodology/Principal Findings Here, Nkx2.7 is demonstrated to compensate for Nkx2.5 loss of function and play a predominant role in the lateral development of the heart, including normal cardiac looping and chamber formation. Knocking down Nkx2.5 showed that heart development was normal from 24 to 72 hpf. However, when knocking down either Nkx2.7 or Nkx2.5 together with Nkx2.7, it appeared that the heart failed to undergo looping and showed defective chambers, although embryos developed normally before the early heart tube stage. Decreased ventricular myocardium proliferation and defective myocardial differentiation appeared to result from late-stage up-regulation of bmp4, versican, tbx5 and tbx20, which were all expressed normally in hearts at an early stage. We also found that tbx5 and tbx20 were modulated by Nkx2.7 through the heart maturation stage because an inducible overexpression of Nkx2.7 in the heart caused down-regulation of tbx5 and tbx20. Although heart defects were induced by overexpression of an injection of 150-pg Nkx2.5 or 5-pg Nkx2.7 mRNA, either Nkx2.5 or Nkx2.7 mRNA rescued the defects induced by Nkx2.7-morpholino(MO) and Nkx2.5-MO with Nkx2.7-MO. Conclusions and Significance Therefore, we conclude that redundant activities of Nkx2.5 and Nkx2.7 are required for cardiac morphogenesis, but that Nkx2.7 plays a more critical function, specifically indicated by the gain-of-function and loss-of- function experiments where Nkx2.7 is observed to regulate the expressions of tbx5 and tbx20 through the maturation stage.
Steganalysis Based on Regression Model and Bayesion Network

In this paper, we propose a feature generation and classification approach for universal steganalysis based on Genetic Algorithm (GA) and higher order statistics. The GA is utilized to select a subset of candidate features, a subset of candidate transformations to generate new features. The Logistic Regression Model and Bayesion Network Model are then used as the classifier. Experimental results show that the GA based approach increases the blind detection accuracy and also provides a good generality by identifying an untrained stego-algorithm.
Spinosad and the Tomato Borer Tuta absoluta: A Bioinsecticide, an Invasive Pest Threat, and High Insecticide Resistance

The introduction of an agricultural pest species into a new environment is a potential threat to agroecosystems of the invaded area. The phytosanitary concern is even greater if the introduced pest’s phenotype expresses traits that will impair the management of that species. The invasive tomato borer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae), is one such species and the characterization of the insecticide resistance prevailing in the area of origin is important to guide management efforts in new areas of introduction. The spinosad is one the main insecticides currently used in Brazil for control of the tomato borer; Brazil is the likely source of the introduction of the tomato borer into Europe. For this reason, spinosad resistance in Brazilian populations of this species was characterized. Spinosad resistance has been reported in Brazilian field populations of this pest species, and one resistant population that was used in this study was subjected to an additional seven generations of selection for spinosad resistance reaching levels over 180,000-fold. Inheritance studies indicated that spinosad resistance is monogenic, incompletely recessive and autosomal with high heritability (h 2 = 0.71). Spinosad resistance was unstable without selection pressure with a negative rate of change in the resistance level ( = −0.51) indicating an associated adaptive cost. Esterases and cytochrome P450-dependent monooxygenases titration decreased with spinosad selection, indicating that these detoxification enzymes are not the underlying resistance mechanism. Furthermore, the cross-resistance spectrum was restricted to the insecticide spinetoram, another spinosyn, suggesting that altered target site may be the mechanism involved. Therefore, the suspension of spinosyn use against the tomato borer would be a useful component in spinosad resistance management for this species. Spinosad use against this species in introduced areas should be carefully monitored to prevent rapid selection of high levels of resistance and the potential for its spread to new areas.
Bacterial population dynamics and faecal short-chain fatty acid (SCFA) concentrations in healthy humans

Fermentation products, SCFA, particularly butyrate, are considered a sign of ‘good’ bowel health but the influence of bacterial population composition and diet on inter-individual difference in metabolites and colonic health is poorly understood. Faecal specimens were collected weekly from eight healthy human volunteers over 12 weeks. Dietary intake was self-reported and ten macronutrient factors were analysed at selected weekly periods. Faecal weight, pH and moisture were recorded, and SCFA concentrations were measured in all samples. From each specimen, DNA was prepared and eubacterial 16S rRNA gene PCR performed. Bacterial population profiles were captured by denaturing gradient gel electrophoresis (DGGE) of PCR products, and multivariate statistical analysis was performed. Faecal weight, pH and moisture varied widely within and between individuals. Average total SCFA concentrations over 12 weeks ranged from 36·9 to 144·4 mmol/kg in 48 h specimens and faecal butyrate concentrations ranged from 1·8 to 48·5 mmol/kg. Two individuals with butyrate concentrations below 10 mmol/kg were considered to be ‘low butyrate types’ and may represent an at-risk population for bowel health. Dietary fat, sugar and carbohydrate showed weak correlation with SCFA (R − 0·612, P = 0·015; R 0·607, P = 0·016; R 0·610, P = 0·016, respectively) and butyrate concentrations (R − 0·593, P = 0·02; R 0·504, P = 0·054; R 0·528, P = 0·043, respectively). Multivariate analysis of DGGE bacterial profiles demonstrated concise and repeated grouping of intra-individual samples, but these were combined with distinct inter-individual differences (analysis of similarities P < 0·001, R ≥ 0·99) The exact relationship of these SCFA values to the overall bacterial profiles and SCFA-producer bacterial groups was not direct nor linear.
Line-of-sight velocity distribution corrections for Lick/IDS indices of early-type galaxies

We investigate line-of-sight velocity distribution (LOSVD) corrections for absorption line-strength indices of early-type galaxies in the Lick/IDS system. This system is often used to estimate basic stellar population parameters such as luminosity weighted ages and metallicities. Using single stellar population model spectral energy distributions by Vazdekis (1999) we find that the LOSVD corrections are largely insensitive to changes in the stellar populations for old galaxies (age > 3 Gyr). Only the Lick/IDS Balmer series indices show an appreciable effect, which is on the order of the correction itself. Furthermore, we investigate the sensitivity of the LOSVD corrections to non-Gaussian LOSVDs. In this case the LOSVD can be described by a Gauss-Hermite series and it is shown that typical values of h 3 and h 4 observed in early-type galaxies can lead to significant modifications of the LOSVD corrections and thus to changes in the derived luminosity weighted ages and metallicities. A new, simple parameterisation for the LOSVD corrections, taking into account the h 3 and h 4 terms, is proposed and calibrations given for a subset of the Lick/IDS indices and two additional indices applicable to old (>3 Gyr) stellar populations.
Access to the labour market for gays and lesbians: Research review

ABSTRACT This article reviews findings of scientific studies looking into the bias that gay men and lesbians face when accessing the labor market. Studies in this topic were scarce before year 2000, but a considerable body of literature appeared in the Western countries in the recent years. When summed up, the findings provide robust evidence that lesbians and gay men face negative bias when accessing employment. The magnitude of the bias varies considerably across contexts. Different labor market outcomes of gay men and lesbians are also partially caused by differences in household specialization between different-sex and same-sex households. Future research needs to address the contextual differences in bias against gay men and lesbians.
Biplot analysis of multi-environment trial data: Principles and applications

Biplot analysis has evolved into an important statistical tool in plant breeding and agricultural research. Here we review the basic principles of biplot analysis and recent developments in its application in analyzing multi-environment trail (MET) data, with the aim of providing a working guide for breeders, agronomists, and other agricultural scientists on biplot analysis and interpretation. The review is divided into four sections. The first section is a complete but succinct description of the principles of biplot analysis. The second section is a detailed treatment of biplot analysis of genotype by environment data. It addresses environment and genotype evaluation from all perspectives. The third section deals with biplot analysis of various two-way tables that can be generated from a three-way MET dataset, which is an integral and essential part to a fuller understanding and exploration of MET data. The final section discusses questions that are frequently asked about biplot analysis. Methods descri.
Strong Decrease in Streptomycin-Resistance and Absence of XDR 12 Years after the Reorganization of the National Tuberculosis Control Program in the Central Region of Cameroon

Background In the 1990s, resistance rates of 15% for streptomycin-resistance and 0.6% for multidrug-resistance (MDR) were reported from the Central Region of Cameroon. This work assesses drug resistant tuberculosis in this region 12 years after reorganization of the National Tuberculosis Control Program (NTCP). Methods This cross-sectional study was conducted from April 2010 to March 2011 in Jamot Hospital in Yaoundé, Cameroon. Only patients with smear positive pulmonary tuberculosis were included. Sputa were cultured and subsequently underwent drug susceptibility testing (DST). All consenting individuals were tested for their HIV status. Results A total of 665 smear positive pulmonary tuberculosis patients were enrolled. The HIV prevalence was 28.5% (95%CI [25.2–32.1]). Of the 582 sputa that grew Mycobacterium tuberculosis complex species, DST results were obtained for 576. The overall resistance rate was 10.9% (63/576). The overall resistance rates for single drug resistance were: isoniazid-resistance 4.7% (27/576), streptomycin-resistance 3.3% (19/576), rifampicin-resistance 0.2% (1/576), kanamycin-resistance 0.2% (1/576) and ofloxacin-resistance 0.2% (1/576). The MDR rate was 1.1% (6/576) and no extensively drug resistant tuberculosis (XDR) was detected. Conclusions The data show that reorganization of the NTCP resulted in a strong decrease in streptomycin-resistance and suggest that it prevented the emergence of XDR in the Central Region of Cameroon.