Miracle-dz/UniFAR-FTUs huggingface dataset:
Young people’s search for agency: Making sense of their experiences and taking control

This article draws on the findings of the qualitative phase of a New Zealand longitudinal study on vulnerable young people’s transitions to adulthood. The young people were aged between 12 and 17 years at the time of the first interview. The paper focuses on one key finding, how youth enact agency through their relationships with significant others: families, social workers, teachers and care workers. These youth had experienced sustained exposure to harm including abuse, violence, addictions, disengagement from school and mental health issues. The qualitative interviews focused on young people’s experiences with services (child welfare, juvenile justice, mental health and education support services) their key transitions, and the strategies they used to locate support and resources. The thematic analysis of the interviews indicated that a search for agency was a central motif in young people’s experiences. This was reflected in three thematic clusters: making sense of the world, having a voice and acting on the world.
Seasonal spatial dynamics and causes of nest movement in colonies of the invasive Argentine ant (Linepithema humile)

Abstract 1. Colony organisation and movement behaviour of the Argentine ant (Linepithema humile) was studied over 3 years in field populations in California and in captive colonies in the laboratory. This invasive species is highly polydomous and unicolonial; colonies consist of expansive and fluid networks of nests and trails. The spatial and temporal organisation of colonies may contribute to ecological dominance.
Relation of type 2 diabetes to individual admixture and candidate gene polymorphisms in the Hispanic American population of San Luis Valley, Colorado

The prevalence of type 2 diabetes is higher in populations of Native American ancestry, and in Hispanic American populations formed by admixture between Europeans and Native Americans, than in populations of European ancestry.1 One approach to distinguishing between environmental and genetic explanations for this difference is to study the relationship of type 2 diabetes risk to individual admixture proportions (the proportions of an individual’s genome that are of European and Native American ancestry). With only a few markers informative for ancestry, it is possible to estimate the average admixture proportions of any Hispanic American population. In such analyses, it has been possible to demonstrate that the prevalence of type 2 diabetes in Hispanic Americans in the south western United States varies with the average Native American admixture proportion of these populations.2–4 In the Native American population of Gila River, Arizona, USA, European admixture is associated with lower prevalence of type 2 diabetes.5 However, it has not been possible to demonstrate an association of type 2 diabetes with individual admixture proportions within an Hispanic American population. To estimate the admixture proportions of an individual accurately requires a larger panel of markers: at least 40 markers with average frequency differentials of 0.6 are required to estimate the admixture of an individual with a standard error of no more than 0.1. 6 It is now possible to identify relatively large numbers of such ancestry informative markers from data accumulating in the public domain. For this study we typed a panel of 21 markers chosen to have large differences in frequency between European, Native American, and West African ancestry. The possible relationship of type 2 diabetes risk to individual admixture proportions within Hispanic American populations complicates the interpretation of associations of type 2 diabetes with candidate gene polymorphisms within these …
Ion permeability of artificial membranes evaluated by diffusion potential and electrical resistance measurements (719.1)

A novel model of artificial membranes that provides efficient assistance in teaching the origins of diffusion potentials is proposed. These membranes are made of polycarbonate filters fixed to 12 mm plastic rings and then saturated with a mixture of creosol and n‐decane. Electrical resistance and potential difference across these membranes can be easily measured using low‐cost volt‐ohmmeter and home‐made Ag/AgCl electrodes. The advantage of the model is the lack of ionic selectivity of the membrane, which can be modified by introduction of different ionophores to the organic liquid mixture. Membrane treated with the mixture containing valinomycin generates voltages from ‐53 mV to ‐25 mV in the presence of a 10‐fold KCl gradient (in‐to‐out) and from ‐79 mV to ‐53 mV in the presence of a bi‐ionic KCl/NaCl gradient (in‐to‐out). This latter bi‐ionic gradient potential reverses to a value from +9 mV to +20 mV when monensin is present in the organic liquid mixture. Thus, the model can be build stepwise, i.e. all factors leading to the development of diffusion potentials can be introduced sequentially, helping to understand the quantitative relationships of ionic gradients and differential membrane permeability in the generation of cell electrical signals.
[Preliminary research on the mechanism of apoptosis hepatic stellate cells induced by zedoary turmeric oil].

在各种治疗肝纤维化的方法中,以肝星状细胞(HSC)为靶点成为目前的研究热点 [1-2]. 国艳等 [3]研究发现,莪术油注射液对体外培养的HSC有明显促凋亡作用,但其凋亡机制尚不清楚. 我们进一步检测和证实了莪术油注射液对HSC的促凋亡作用;并同时检测促凋亡基因Fas、抑凋亡基因bcl-2与凋亡蛋白酶caspase-3,试图揭示莪术油注射液促进HSC凋亡作用的可能机制。
An investigation of mitochondrial inner membranes by rapid-freeze deep- etch techniques

Physical fixation by rapid freezing followed by freeze-fracture and deep-etching has provided the means for potentially seeing the three- dimensional arrangement in the native state of particles on mitochondrial inner membranes. We have used these techniques to study the tubular cristae of Paramecium in the hope of determining the arrangement of F1 complexes, their abundance, and location in the membranes. We also sought information regarding other respiratory complexes in these membranes. Our results, supported by stereo pairs, show that F1 complexes are arranged as a double row of particles spaced at 12 nm along each row as a zipper following the full length of the outer curve of the helically shaped tubular cristae. There are an average of 1,500 highly ordered F1 complexes per micrometer squared of 50-nm tubular cristae surface. The F1 complexes definitely lie outside the membranes in their native state. Other particle subsets, also nonrandomly arrayed, were seen. One such population located along the inner helical curve consisted of large 13-nm-wide particles that were spaced at 30 nm center-to-center. Such particles, because of their large size and relative abundance when compared to F1 units, resemble complex I of the respiratory complexes. Any models attempting to understand the coupling of respiratory complexes with F0F1 ATPase in Paramecium must take into account a relatively high degree of order and potential immobility of at least some of these integral membrane complexes.
Toward a culturally sensitive conceptualization of resilience: Participatory research with war-affected communities in northern Uganda

Resilience research with war-affected populations has long conceptualized resilience as the absence of psychopathology and operationalized it by use of standardized measures. However, literature on resilience increasingly highlights the importance of also including indicators of positively valued functioning as well as contextually sensitive indicators of resilience. This study used a participatory approach to examine the contextual conceptualization of youth resilience in the aftermath of war in northern Uganda, as defined by groups of stakeholders (youths, parents, elders, leaders, teachers) in four communities. The results identify 40 indicators covering a multiplicity of domains of functioning. The rationales behind these indicators were clustered into the broad themes: progress, self-reliance, social connectedness, morality, health, and comfort. The findings suggest that positively and negatively valued aspects of functioning are both key to conceptualizing resilience, and indicate the importance of including contextually distinguished indicators. The findings further point to the role of individual and collective processes in the construction of resilience, and to the need to take into account the contexts wherein resilience is conceptualized and observed. This study generated contextually sensitive indicators of young people’s resilience, which can be used, complementary to existing measures of functioning, to provide a more comprehensive and culturally sensitive view of youths’ resilience in the wake of war adversity.
Criminal Identities and Consumer Culture: Crime, Exclusion and the New Culture of Narcissm

This book offers the first in-depth investigation into the relationship between today’s criminal identities and consumer culture. Using unique data taken from criminals locked in areas of permanent recession, the book aims to uncover feelings and attitudes towards a variety of criminal activities, investigating the incorporation of hearts and minds into consumer culture’s surrogate social world and highlighting the relationship between the lived identities of active criminals and the socio-economic climate of instability and anxiety that permeates post-industrial Britain. This book will be of interest to undergraduates, postgraduates, researchers and lecturers in all fields within the social sciences, but especially criminology, sociology, social policy, politics and anthropology.
An Additive Simple View of Reading Describes the Performance of Good and Poor Readers in Higher Education.

According to Gough and Tunmer (1986), in a ‘Simple View of Reading’ (SVR), Reading comprehension (RC) = Decoding (D) x Linguistic Comprehension (C). To further evaluate this model, this paper describes an exploratory study of the performance of 60 university students, the majority of whom received academic accommodations at university to compensate for significa nt reading delays. Results showed that both D and C predicted reading comprehension well. An additive model (D + C) fitt ed the data no bett er than a product model (D x C). Similar results were obtained when cumulative grade point average rather than reading comprehension was used as the dependent variable. D but not RC was correlated with phonological awareness and (less reliably) with rapid naming ability. Implications of these find ings for the Simple View of Reading and for the support of university students with reading problems are considered. ISSN 1918-5227 Pages 243- 268 Follow this and additional works at: htt p://ir.lib. uwo.ca/eei
Infection Paradox: High Abundance but Low Impact of Freshwater Benthic Viruses

ABSTRACT The discovery of an abundant and diverse virus community in oceans and lakes has profoundly reshaped ideas about global carbon and nutrient fluxes, food web dynamics, and maintenance of microbial biodiversity. These roles are exerted through massive viral impact on the population dynamics of heterotrophic bacterioplankton and primary producers. We took advantage of a shallow wetland system with contrasting microhabitats in close proximity to demonstrate that in marked contrast to pelagic systems, viral infection, determined directly by transmission electron microscopy, and consequently mortality of prokaryotes were surprisingly low in benthic habitats in all seasons. This was true even though free viruses were abundant throughout the year and bacterial infection and mortality rates were high in surrounding water. The habitats in which we found this pattern include sediment, decomposing plant litter, and biofilms on aquatic vegetation. Overall, we detected viruses in only 4 of a total of ∼15,000 bacterial cells inspected in these three habitats; for comparison, nearly 300 of ∼5,000 cells suspended in the water column were infected. The strikingly low incidence of impact of phages in the benthos may have important implications, since a major portion of microbial biodiversity and global carbon and nutrient turnover are associated with surfaces. Therefore, if failure to infect benthic bacteria is a widespread phenomenon, then the global role of viruses in controlling microbial diversity, food web dynamics, and biogeochemical cycles would be greatly diminished compared to predictions based on data from planktonic environments.
Examination of Whole Blood DNA Methylation as a Potential Risk Marker for Gastric Cancer

Whole blood DNA methylation analysis has been proposed to be a risk marker for cancer that can be used to target patients for preventive interventions. To test this, we examined whole blood DNA methylation of 16 CpG island promoters and LINE1 repetitive element in patients with gastric cancer and control subjects. Bisulfite pyrosequencing was used to quantify the methylation of 14 CpG island promoters (MINT25, RORA, GDNF, CDH1, RARAB2, ER, CDH13, MYOD1, SFRP1, P2RX7, SLC16A12, IGF2, DPYS, and N33) and LINE1 from 72 patients with gastric cancer, 67 control, and 52 healthy young individuals. Quantitative methylation-specific real-time PCR was also conducted for 3 CpG island promoters (MINT25, MYO3A, and SOX11). Among all sites tested, only a marginal increase in the methylation of the SFRP1 promoter was observed in the blood of patients with gastric cancer when compared with the control group (11.3 % vs 10.5%; age-adjusted P value: P = 0.009), and this association was also seen in a validation set of 91 patients with gastric cancer (11.5% vs 10.5%; age-adjusted P value: P = 0.001). The methylation of 9 sites (GDNF, CDH1, RARAB2, CDH13, MYOD1, SFRP1, SLC16A12, DPYS, N33, and LINE1) and their mean Z score was correlated with higher age (R = 0.41, P < 0.0001) and marginally with telomere shortening (R = −0.18, P = 0.01) but not with gastric cancer risk (other than SFRP1 methylation). Variability in whole blood DNA methylation of cancer markers is primarily associated with aging, reflecting turnover of white blood cells, and has no direct link to gastric cancer predisposition. SFRP1 methylation in whole blood may be associated with gastric cancer risk. Cancer Prev Res; 6(10); 1093–100. ©2013 AACR.
Occluded Boundary Detection for Small-Footprint Groundborne LIDAR Point Cloud Guided by Last Echo

Occluded boundary detection in a 3-D point cloud is an indispensable preprocessing step for many applications, such as point cloud completion. Meanwhile, existing methods do not have the ability of distinguishing occluded and complete surface borders, such as the border of a sign board. To solve this problem, this letter presents an occluded boundary detection method for small-footprint LIDAR point clouds. The main novelty of this letter is using the last-echo information for occluded boundary detection. Seed boundary (SB) points are subsequently detected using this last-echo information. Finally, the SB points are grown into neighboring points using an occluded boundary growth algorithm. To the best of our knowledge, this method is the first method that uses the last-echo information to detect occluded boundaries. Experimental results with comparisons indicate that the proposed method can accurately and efficiently detect an occluded boundary without contamination from a complete surface border. These advantages allow the proposed method to benefit further applications such as point cloud completion, as demonstrated in the application section.
Effects of physical activity intervention combining a new sport and mindfulness yoga on psychological characteristics in adolescents

This study investigated the effects of physical activity intervention combining a new sport and mindfulness yoga on psychological characteristics in adolescents. The study employed a pre- and post-test with the two-group longitudinal design. A total of 46 primary school students voluntarily participated in the 8-week intervention (male: 25, female: 21; Mage = 10.98, SD = 0.39). Self-esteem, resilience, and happiness were measured at the pre- and post-intervention. The intervention included new sport and mindful yoga associated with psychological attributes. Specifically, new sports consisted of various sport activities including kinball and the mindful yoga programme included proper breathing and Hatha yoga 1 and 2. Results indicated that in the experimental group, the study participants’ self-esteem (F = 3.47, p = .049), resilience (F = 9.72, p = .003), and happiness (F = 31.61, p = .001) were significantly changed over the 8-week intervention. This study suggests that both physical activity and mindfulness yoga influence psychological attributes when planning and implementing physical activity promotion.
First Report of Necrophagous Insects on Human Corpses in Riyadh, Saudi Arabia

Abstract Necrophagous species of insects provide useful complementary data to estimate the postmortem interval in forensic cases. Here, for the first time, we report on insect specimens collected from human corpses in Riyadh, Kingdom of Saudi Arabia. During the study, 14 beetle larvae were collected from the outdoor corpse (case report one) and five flies and seven beetles were collected from the indoor corpse (case report two). Sequencing was performed to study the mitochondrial DNA (mtDNA) as the prospective basis of an identification technique. The sequencing focused on a section of the cytochrome oxidase I encoding region of mtDNA. Two beetle species, Dermestes frischii (Kugelann) and Dermestes maculatus (De Geer) (Coleoptera: Dermestidae), and one fly species, Chrysomya albiceps (Wiedemann) (Diptera: Calliphoridae), were identified. These results will be instrumental in the implementation of a Saudi database of forensically relevant insects.
Bicultural Competence and its Impact on Team Effectiveness

This paper develops the concept of bicultural competence and explores its impact on multicultural team effectiveness. Biculturals are individuals who have deeply internalized two cultural schemas. A cultural schema is a set of knowledge about values, norms, and beliefs for a given culture. Biculturals are an increasing workforce demographic, and hence a growing part of multicultural teams. Their innate skills that result from being bicultural may help solve central problems in multicultural teams, including managing conflicts and boundary spanning across cultures. Specifically, this paper defines bicultural competence, determines its antecedents, specifies its impact on the two main roles bicultural individuals play in teams, and explores their impact on multicultural team effectiveness. Theoretical and practical implications are discussed. La compétence biculturelle et son impact sur l’efficacité de l’équipe (Hae-Jung Hong) Cet article développe le concept de la compétence biculturelle et en explore l’impact sur l’efficacité multiculturelle de l’équipe. La personne biculturelle est quelqu’un qui a profondément internalisé deux schémas culturels. Un schéma culturel est un ensemble de connaissances relatives aux valeurs, normes et croyances d’une culture donnée. Les biculturels représentent une donnée démographique de plus en plus importante de la population active, et forment donc un élément croissant d’équipes multiculturelles. Leurs compétences innées, résultant de ce biculturalisme, peuvent aider à résoudre certains problèmes au cœur des équipes multiculturelles, dont la gestion des conflits et la capacité à jeter des ponts entre cultures. Plus spécifiquement, cet article définit la compétence culturelle, détermine ses antécédents, en spécifie son impact sur les deux principaux rôles que les biculturels jouent au sein des équipes, et explore l’impact de ceux-ci sur l’efficacité des équipes multiculturelles. Les implications théoriques et pratiques sont abordées.
Moving object classification using horizontal laser scan data

Motivated by two potential applications, i.e. enhancing driving safety and traffic data collection, a system has been developed using a single-layer horizontal laser scanner as the major sensor for both localization and perception of the surroundings in a large dynamic urban environment. This research focuses on a classification method, that given a stream of laser measurements, classify the moving object into either a person, a group of people, a bicycle or a car. In this research, a number of features are defined after examining the property of data appearance. A classification method is proposed after examining the likelihood measures between each pair of feature and class. Experimental results are presented, demonstrating that the algorithm has efficiency with respect to both driving safety and traffic data collection in highly dynamic environment.
Research Cultures in English and Scottish University Education Departments: An Exploratory Study of Academic Staff Perceptions.

The paper reports the findings of a small-scale qualitative investigation into academic staff perceptions of research cultures across 10 English and Scottish university education departments. The study sheds light on four interrelated issues: the nature of research cultures, perceived facilitators, perceived constraints and the emotional landscape of working within a research environment. The findings indicate that perceptions vary according to staff academic and scientific capital, largely determined by career background and the type of university institution in which they work. While there is evidence of a culture of performativity and intensification, there is also evidence of widespread commitment to (and enjoyment of) educational research, especially where its value is broadly conceived to include outputs of applied research (including action research) as well as basic and strategic research. It is concluded that a broader policy conception of what constitutes value in research, coupled with a deeper.
Role of Tyrosine Phosphorylation in U46619-induced Vasoconstriction of Pulmonary Vasculature and Its Modulation by Genistein, Daidzein, and Equol

We compared the effects of genistein with its structural derivatives daidzein and equol on excitation of pulmonary artery and vein. The concentration of genistein necessary to inhibit contractions evoked by U46619 (1nM-100 uM) ranged from 10 to 100 μM. Genistein (55 μM) reduced KCl-responses by ∼50% and essentially abolished those evoked by U46619. Daidzein was much less effective against either agonist, and equol was ineffective against U46619. A23187-evoked contractions were markedly reduced by all 3 isoflavones, but caffeine-evoked contractions were not. Using the Western blot technique, we found many proteins were tyrosine phosphorylated within 30 seconds after stimulation with U46619, reaching a peak at 120 seconds and then falling at 300 seconds. One band at 110 kD was increased nearly 300% above baseline, while 3 others ranging from 60 to 80 kD were more than doubled in intensity. Genistein had little effect on baseline levels of phosphorylation but largely prevented the U46619-induced change; daidzein was much less effective in this respect, and equol did not significantly affect this phosphorylation. We conclude that these isoflavones provide powerful tools in the study of excitation-contraction coupling of pulmonary vasculature and that inhibition of tyrosine kinase activity may be useful clinically against pulmonary hypertension.