Miracle-dz/UniFAR-FTUs huggingface dataset:
Factors of body image dissatisfaction among high school female athletes

xi CHAPTER ONE: INTRODUCTION 1 CHAPTER TWO: LITERATURE REVIEW 2 Risk Factors Among Female Athletes 2 Protective Factors Among Female Athletes 4 Type of Sport and Body Image Dissatisfaction 6 High School Sport Participation 8 Maternal Eating Disturbance and Body Image Dissa ti faction 9 Family Dynamics 11 Self-Efficacy 14 Purpose of the Study 17 Hypotheses 18 CHAPTER THREE: METHOD SECTION 19 Participants 19 Procedure 19 Measures 21 CHAPTER FOUR: RESULTS SECTION 25 Data Preparation 25 Preliminary Analyses to Assess Group Differences Across Sports 26 Regression Analyses to Identify Covariates 31 Overview of Statistical Analyses 35 CHAPTER FIVE: DISCUSSION SECTION 56 APPENDIX A: PARENT CONSENT FORM 73 APPENDIX B: ATHLETE ASSENT FORM 76 APPENDIX C: DEBREIFING FORM 79 APPENDIX D: ATHLETE DEMOGRAPHIC QUESTIONNAIRE 81 vii APPENDIX E: MOTHER DEMOGRAPHIC QUESTIONNAIRE 86 APPENDIX F: EATING DISORDER INVENTORY-3 (EDI-3) – BODY DISSATISFACTION SUBSCALE 90 APPENDIX G: FIGURE RATING SCALE (FRS) 93 APPENDIX H: FAMILY ENVIRONMENT SCALE (FES) – COHESI ON, EXPRESSIVENESS, CONFLICT, INDEPENDENCE 96 APPENDIX I: NEW GENERAL SELF-EFFICACY SCALE (NGSE) 102 REFERENCES 105 VITA 118
An experience with mesh versus darn repair in inguinal hernias

Background & Objective: The inguinal hernia accounts for 50 percent in old age males. A Lichtenstein type of operation has now become the method of choice in most developed countries but in the developing world traditional simple suture repair is still in common practice in resource limited hospitals due to the scarcity and expensive nature of the commercial prosthetic mesh. Our objective was to compare the rates of complications in Lichtenstein repair to tension free Darn repair. Methods: Ninety two male patients from 20-60 years of age reported for direct or indirect inguinal hernia with open Mesh/Lichtenstein or darn repair in emergency or electively from January 2014 to December 2015 were enrolled in this prospective randomized control trial (RCT). The primary end point was to compare the surgical site infection, length of hospital stay and hernia recurrence with different techniques. Results: The hospital stay was higher in patients who had Lichtenstein repair, Superficial surgical site infections in cohort A (6.5%) and cohort B (4.36%)were noted. Complications of recurrence in Group-A were (1.5%) as compared to Group-B which had a recurrence of 6.52%. Conclusion: Lichtenstein is more promising in comparison to Darn repair in terms of recurrence in inguinal hernia.
Coset codes-II: Binary lattices and related codes

For pt.I see ibid., vol.34, no.5, p.1123-51 (1988). The family of Barnes-Wall lattices (including D/sub 4/ and E/sub 8/) of lengths N=2/sup n/ and their principal sublattices, which are useful in constructing coset codes, are generated by iteration of a simple construction called the squaring construction. The closely related Reed-Muller codes are generated by the same construction. The principal properties of these codes and lattices are consequences of the general properties of iterated squaring constructions, which also exhibit the interrelationships between codes and lattices of different lengths. An extension called the cubing construction generates good codes and lattices of lengths N=3*2/sup n/, including the Golay code and Leech lattice, with the use of special bases for 8-space. Another related construction generates the Nordstrom-Robinson code and an analogous 16-dimensional nonlattice packing. These constructions are represented by trellis diagrams that display their structure and interrelationships and that lead to efficient maximum-likelihood decoding algorithms. >
IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis

Objectives Indoleamine 2,3-dioxygenase-1 (IDO1) is an immune-modulatory enzyme that catalyzes the degradation of tryptophan (Trp) to kynurenine (Kyn) and is strongly induced by interferon (IFN)-γ. We previously reported highly increased levels of IFN-γ and corresponding IDO activity in patients with hemophagocytic lymphohistiocytosis (HLH), a hyper-inflammatory syndrome. On the other hand, IFN-γ and IDO were low in patients with systemic juvenile idiopathic arthritis (sJIA), an autoinflammatory syndrome. As HLH can occur as a complication of sJIA, the opposing levels of both IFN-γ and IDO are remarkable. In animal models for sJIA and HLH, the role of IFN-γ differs from being protective to pathogenic. In this study, we aimed to unravel the role of IDO1 in the pathogenesis of sJIA and HLH. Methods Wild-type and IDO1-knockout (IDO1-KO) mice were used in 3 models of sJIA or HLH: complete Freund’s adjuvant (CFA)-injected mice developed an sJIA-like syndrome and secondary HLH (sHLH) was evoked by either repeated injection of unmethylated CpG oligonucleotide or by primary infection with mouse cytomegalovirus (MCMV). An anti-CD3-induced cytokine release syndrome was used as a non-sJIA/HLH control model. Results No differences were found in clinical, laboratory and hematological features of sJIA/HLH between wild-type and IDO1-KO mice. As IDO modulates the immune response via induction of regulatory T cells and inhibition of T cell proliferation, we investigated both features in a T cell-triggered cytokine release syndrome. Again, no differences were observed in serum cytokine levels, percentages of regulatory T cells, nor of proliferating or apoptotic thymocytes and lymph node cells. Conclusions Our data demonstrate that IDO1 deficiency does not affect inflammation in sJIA, sHLH and a T cell-triggered cytokine release model. We hypothesize that other tryptophan-catabolizing enzymes like IDO2 and tryptophan 2,3-dioxygenase (TDO) might compensate for the lack of IDO1.
Clinical profile of dengue infection at a teaching hospital in North India.

INTRODUCTION Dengue viral infections are among the most important mosquito-borne diseases of the Indian subcontinent and have become a major global public health concern. Spread of disease has led to increased recognition of atypical manifestations apart from the classical clinical features of dengue infection. METHODOLOGY A cross-sectional study of admitted patients suspected to have dengue infection was conducted during the monsoon and post-monsoon seasons in the year 2010. Patients who had serological confirmation of dengue infection were classified according to World Health Organization definitions of dengue fever and dengue hemorrhagic fever. Clinical and biochemical parameters were compared between the two groups. RESULTS Out of 356 patients with suspected dengue fever enrolled in the study, 138 (39%) had serologically confirmed dengue infection. Eighty (58%) patients were males and 58 (42%) were females. Ninety-six (70%) patients had classical dengue fever while 42 (30%) had dengue hemorrhagic fever. The most common symptoms were headache (105, 76%), abdominal pain (87, 63%), vomiting (80, 58%), rash (36, 26%), and cutaneous hypersensitivity (22, 16%). Hemorrhagic manifestations were present in 55 (40%) patients. Atypical manifestations were recorded. Notably, 14% of patients had neurological involvement and 4% had acute hepatic failure. Overall mortality was 6% and all fatal cases were due to multi-organ failure. CONCLUSION Dengue infection poses a huge burden to the health-care system; its spectrum ranges from mild self-limiting illness to severe fatal disease. It can have varied and multi-systemic manifestations which can go unrecognized. Clinicians should have a high index of suspicion for atypical manifestations.
Job burnout and cognitive functioning: A systematic review

Although it is generally accepted that burnout has an effect on cognitive functioning, very few studies have so far examined the link between cognitive functioning and job burnout. The purpose of this systematic review was to explore the reported association between burnout and cognitive functioning, as assessed objectively (that is, using psychometric tests rather than self-reports). The review identified 15 English-language articles published between 2005 and 2013. The results suggest that burnout is connected to specific cognitive deficits. In particular, burnout has been found to be associated with a decline in three main cognitive functions: executive functions, attention and memory. These results have clear implications, in particular for professions that are characterized by high levels of both work pressure and cognitive demands. Due to the scarcity and heterogeneity of available articles, future longitudinal prospective studies are needed, in order to determine the cognitive functions predominantly impaired as a result of burnout, and to establish causal relationships.
Early Marriage, Women Empowerment and Child Mortality: Married Too Young To Be a «Good Mother»?

This paper uses data from recent Senegalese Demographic and Health Surveys to explore the link between female empowerment and child mortality via early marriage, defined as marriage before age 16. There exist three channels through which early marriage reduces a mother's ability to take good care of her children: the harmful physical consequences of early sex and pregnancy; a disrupted education; and reduced autonomy and bargaining power. Controlling for the first two of these allows us to isolate the empowerment effect of early marriage. We estimate that it increases the probability that the mother experience at least one son death by 4.43%, and raises the number of dead sons per mother by 0.074. Particular attention is paid to discuss and address endogeneity issues. We also further investigate the heterogeneity of impact by current age and marriage duration. Findings suggest that we effectively identify the empowerment channel.
Prediction of residual/recurrent disease by HPV Genotype after loop excision procedure for high‐grade cervical intraepithelial neoplasia with negative margins

Aims: This study aims to evaluate whether the preconisation of high‐risk human papillomavirus (HR‐HPV) genotype and multiple HPV infection is predictive for residual/recurrent disease during the follow‐up of high‐grade cervical intraepithelial neoplasia (CIN) treated by loop electrosurgical excision procedure (LEEP) with negative margins.
Long-term treatment effect of atorvastatin on aortic stiffness in hypercholesterolaemic patients

Summary Aim: To assess the effect of atorvastatin on aortic stiffness in hypercholesterolaemic patients free of arterial hypertension and diabetes mellitus. Methods and Results: The study included 36 patients (25 men and 11 women, mean age 56 ± 12 years); 18 patients had stable coronary heart disease (CHD) and 18 were free of CHD at baseline. All patients received atorvastatin (20mg/day) for a 2-year period. Aortic stiffness was assessed by transthoracic echocardiography at baseline and 2 years later. At baseline, total cholesterol, low density lipoprotein cholesterol (LDL-C) and LDL-C/high density lipoprotein cholesterol (HDL-C) ratio were positively related to aortic stiffness (p < 0.001 for all). The mean change in lipid parameters during treatment was: total cholesterol −38%, LDL-C −46%, triglycerides −29%, and HDL-C +6%, all significant (p = 0.029 to <0.0001). After the 2-year treatment with atorvastatin, aortic stiffness was significantly reduced by 14% (p = 0.019). An improvement of left ventricular (LV) ejection fraction by 13% (p < 0.001) and a reduction of LV mass index by 9% (p = 0.008) were also recorded. The change in aortic stiffness was similar in patients with or without CHD. Conclusion: Long-term treatment with atorvastatin improves aortic stiffness; this index is related to total and coronary mortality. Moreover, assessment of aortic stiffness may be useful in identifying which hypercholesterolaemic patients should be treated aggressively, regardless of CHD. The aortic stiffness effect may eventually become an index of the efficacy of lipid lowering treatment.
Regulation of Sialic Acid Catabolism by the DNA Binding Protein NanR in Escherichia coli

ABSTRACT All Escherichia coli strains so far examined possess a chromosomally encoded nanATEK-yhcH operon for the catabolism of sialic acids. These unique nine-carbon sugars are synthesized primarily by higher eukaryotes and can be used as carbon, nitrogen, and energy sources by a variety of microbial pathogens or commensals. The gene nanR, located immediately upstream of the operon, encodes a protein of the FadR/GntR family that represses nan expression in trans. S1 analysis identified the nan transcriptional start, and DNA footprint analysis showed that NanR binds to a region of ∼30 bp covering the promoter region. Native (nondenaturing) polyacrylamide gel electrophoresis, mass spectrometry, and chemical cross-linking indicated that NanR forms homodimers in solution. The region protected by NanR contains three tandem repeats of the hexameric sequence GGTATA. Gel shift analysis with purified hexahistidine-tagged or native NanR detected three retarded complexes, suggesting that NanR binds sequentially to the three repeats. Artificial operators carrying different numbers of repeats formed the corresponding number of complexes. Among the sugars tested that were predicted to be products of the nan-encoded system, only the exogenous addition of sialic acid resulted in the dramatic induction of a chromosomal nanA-lacZ fusion or displaced NanR from its operator in vitro. Titration of NanR by the nan promoter region or artificial operators carrying different numbers of the GGTATA repeat on plasmids in this fusion strain supported the binding of the regulator to target DNA in vivo. Together, the results indicate that GGTATA is important for NanR binding, but the precise mechanism remains to be determined.
No association with hypertension of CLCNKB and TNFRSF1B polymorphisms at a hypertension locus on chromosome 1p36

Objective Chromosome 1p36 has been linked to essential hypertension and systolic blood pressure. This locus contains the chloride channel-Kb gene (CLCNKB) and the tumour necrosis factor receptor 2 gene (TNFRSF1B). Polymorphisms of each of these have shown association with hypertension, and a CLCNKB T481S variant alters receptor function. Here we performed association studies in a well-characterized cohort of hypertensives and normotensives whose blood pressure status matched that of both their parents. Methods The study involved 196 essential hypertensives and 321 normotensives. These were genotyped for TNFRSF1B variants T–1710A upstream, A257G in exon 2, a CA-repeat polymorphism in intron 4, E232K and M196R in exon 6, and T1668G and T1690C in the 3′-untranslated region, and the T481S variant of CLCNKB. Results The CLCNKB T481S variant showed no association with hypertension. Thermodynamic modelling of the 3′-untranslated region of TNFRSF1B mRNA predicted that the T1668G variant alters the stem–loop structure and thus the mRNA stability and expression. However, neither this nor the other TNFRSF1B polymorphisms, either alone or after haplotype analysis, were associated with hypertension. Moreover, for each gene the blood pressure, body mass index, plasma sodium and plasma lipid concentrations were generally similar across genotypes. Conclusion Our data fail to support previous association findings for TNFRSF1B and CLCNKB at the chromosome 1p36 locus implicated in hypertension.
WOMEN'S GENDER PERFORMANCES AND CULTURAL HETEROGENEITY IN THE ILLEGAL DRUG ECONOMY†

Based on interviews with 32 female drug dealers in Norway, this study investigates different gender performances among women situated in the illegal hard drug economy—a context with strong gendered “rules of the game. ” Using grounded theory methods, I have identified four predominant patterns in which women enact their gendered identities being part of the drug economy: performing emphasized femininity in the context of marginalization; performing street masculinity; employing a feminine business model; and last, flexible use of cultural repertoires. The findings suggest that different gender performances among dealers are rooted in variations in the cultural tool kits they have at their disposal. I find that the content of women's cultural tool kits varied with three sociodemographic factors: 1) age, 2) time of entree to the drug economy, and 3) educational and employment history. Combined, these influenced the type of gender performances the dealers tended to use as well as their position in the drug market hierarchy. The research suggests that those dealers using cultural repertoires flexibly are the most successful as they skillfully employed the model best suited for the context they were in.
OCD: obsessive–compulsive … disgust? The role of disgust in obsessive–compulsive disorder

Recent research has identified the important role of disgust in the symptomatology of obsessive–compulsive disorder (OCD). Exaggerated and inappropriate disgust reactions may drive some of the symptoms of OCD, and in some cases, may even eclipse feelings of anxiety. This paper reviews behavioural and neuroimaging research that recognizes the prominent role of disgust in contributing to OCD symptoms, especially contamination-based symptoms. We discuss how elevated behavioural and biological markers of disgust reported in OCD populations support the need for alternative clinical treatment strategies and theoretical models of OCD.
COMPARATIVE STUDY OF ATTRIBUTE SELECTION USING GAIN RATIO AND CORRELATION BASED FEATURE SELECTION

Feature subset selection is of great importance in the field of data mining. The high dimension data makes testing and training of general classification methods difficult. In the present paper two filters approaches namely Gain ratio and Correlation based feature selection have been used to illustrate the significance of feature subset selection for classifying Pima Indian diabetic database (PIDD). The C4.5 tree uses gain ratio to determine the splits and to select the most important features. Genetic algorithm is used as search method with Correlation based feature selection as subset evaluating mechanism. The feature subset obtained is then tested using two supervised classification method namely, Back propagation neural network and Radial basis function network. Experimental results show that the feature subsets selected by CFS filter resulted in marginal improvement for both back propagation neural network and Radial basis function network classification accuracy when compared to feature subset selected by information gain filter.
Can Pulse Oximetry or a Bedside Swallowing Assessment Be Used to Detect Aspiration After Stroke?

Background and Purpose— Desaturation during swallowing may help to identify aspiration in stroke patients. This study investigated pulse oximetry, bedside swallowing assessment (BSA), and videofluoroscopy as tests for detecting aspiration after stroke. Methods— Swallowing was assessed in 189 stroke patients (mean±SD age, 70.9±12.3 years) within 5 days of symptom onset with a modified BSA (water replaced by radio-opaque contrast agent, followed by chest radiography to detect aspiration). Simultaneous pulse oximetry recorded the greatest desaturation from baseline for 10 minutes from modified BSA onset. Videofluoroscopy was undertaken in 54 (28%) patients. Results— Modified BSA showed a safe swallow in 98 (51.9%), unsafe swallow in 85 (45.0%), and silent aspiration in 6 (3.2%) patients. During swallowing, desaturation by >2% occurred in 27 (27.6%) and by >5% in 3 (3.1%) of the 98 safe-swallow patients on modified BSA. Of the 85 unsafe-swallow patients, only 28 (32.9%) desaturated by >2% and 6 (7.1%) by >5%. Desaturation did not occur in any of the 6 silent aspirators. With the modified BSA to detect aspiration, sensitivity and specificity, respectively, were 0.31 and 0.72 for desaturation >2% and 0.07 and 0.97 for desaturation >5%. By videofluoroscopy, sensitivity and specificity for detecting aspiration were 0.47 and 0.72 for modified BSA, 0.33 and 0.62 for desaturation >2%, and 0.13 and 0.95 for desaturation >5%. Combining a failed modified BSA with desaturation >2% or >5% did not significantly improve predictive values. Conclusions— Modified BSA and pulse oximetry during swallowing, whether alone or in combination, showed inadequate sensitivity, specificity, and predictive values for detection of aspiration compared with videofluoroscopy in stroke patients.
Serious adverse events in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD).

AIMS The study estimated serious adverse event (SAE) rates among entrants to pharmacotherapies for opioid dependence, during treatment and after leaving treatment. DESIGN A longitudinal study based on data from 12 trials included in the Australian National Evaluation of Pharmacotherapies for Opioid Dependence (NEPOD). PARTICIPANTS AND SETTINGS A total of 1244 heroin users and methadone patients treated in hospital, community and GP settings. Intervention Six trials included detoxification; all included treatment with methadone, buprenorphine, levo-alpha-acetyl-methadol (LAAM) or naltrexone. FINDINGS During 394 person-years of observation, 79 SAEs of 28 types were recorded. Naltrexone participants experienced 39 overdoses per 100 person-years after leaving treatment (44% occurred within 2 weeks after stopping naltrexone). This was eight times the rate recorded among participants who left agonist treatment. Rates of all other SAEs were similar during treatment versus out of treatment, for both naltrexone-treated and agonist-treated participants. Five deaths occurred, all among participants who had left treatment, at a rate of six per 100 person-years. Total SAE rates during naltrexone and agonist treatments were similar (20, 14 per 100 person-years, respectively). Total SAE and death rates observed among participants who had left treatment were three and 19 times the corresponding rates during treatment. CONCLUSIONS Individuals who leave pharmacotherapies for opioid dependence experience higher overdose and death rates compared with those in treatment. This may be due partly to a participant self-selection effect rather than entirely to pharmacotherapy being protective. Clinicians should alert naltrexone treatment patients in particular about heroin overdose risks. Duty of care may extend beyond cessation of dosing.
Public spheres in interaction: : Comment sections of news websites as counterpublic spaces

Research scrutinizing political talk online has been developed largely against the backdrop of deliberative discursive norms and considered political talk without a systematic analysis of surrounding mass-mediated discourses. By contrast, this study operationalizes counterpublic theory as an alternative theoretical perspective and analyzes comments on news websites as a reaction to hegemonic mainstream public spheres. It juxtaposes a qualitative framing analysis of all articles about a new anti-Euro party in devotedly pro-European Germany published on 9 news websites in the week following the 2013 elections (n = 22) with a content analysis of all comments posted below these articles (n = 3,154). It finds counterpublic spheres differently shaped in comment sections of right- and left-leaning, and tabloid and nontabloid, outlets. Consequences for democracy are discussed.