Miracle-dz/UniFAR-FTUs huggingface dataset:
Online Peer Discourse in a Writing Classroom.

This paper is an attempt to explore the interaction discourse of second language undergraduate learners in the online peer review process of a writing classroom in Hong Kong. Specifically, the writer sought to investigate the types of online discourse learners have in the peer discussions on their writing, and to examine the role of explicit instructions and training for producing quality online peer discourses. Finally, she hoped to understand how instructors could better support and facilitate effective online discourse in peer reviews. Ongoing developments in Hong Kong’s higher education call for implementation of more innovative technology-assisted teaching methods that emphasize learner autonomy; thus, this study examines online discourse that occurred during the peer review process in a writing class in which learners assisted one another in revising their writing with the help of technology. The study was conducted on a group of first-year part-time undergraduate students in an Early Childhood Education program in Hong Kong. In this paper, the online peer discourse was assessed by examining the types of comments students made for their peers during two writing tasks: a group task and an individual task. To facilitate the analyses of peer responses, a coding scheme was used (Liang, 2008). Results show that students tended to give more positive revision-related comments and that explicit instruction and training had an impact on the quality and quantity of online discourse. In conclusion, the author identifies several essential
The Glass Is Neither Half Full Nor Empty, It Is Shattered: a Prospective Study of Shattered Assumptions Theory and Psychological Flexibility

Shattered assumptions theory posits that each individual has a core set of assumptions about the world and the self, often termed the assumptive world which includes: the world is a benevolent place, the world is meaningful, and the self is worthy. Experiencing a traumatic event is believed to lead individuals to question these assumptions in light of the new contradictory information that causes the assumptive world to shatter, leaving the individual to rebuild a more negative perception of the world and themselves. This rebuilding of a fragile new set of core beliefs is believed to be a cause of posttraumatic stress disorder (PTSD) symptoms. Although shattered assumptions theory has been widely accepted in the field of trauma psychology, the shattering of the assumptive world has not been empirically supported due to measurement issues and poor research designs. The current study implemented a prospective design to assess a new measure of the individual’s assumptive world when there is an intervening trauma. In a college sample (N = 336), individuals who experienced a traumatic event over the course of the semester (n = 40) evidenced decreases in optimism in their assumptive worlds, in comparison to individuals who did not experience a traumatic event. The results suggest there is a limited shattering of the assumptive world for those who experienced a traumatic event. Applications, limitations and future directions are discussed.
Differential display and integrin alpha 6 messenger RNA overexpression in hepatocellular carcinoma

Our aim was to isolate potentially important differentially expressed gene products from paired human hepatocellular carcinoma (HCC) and normal liver samples using the differential messenger RNA (mRNA) display technique. Total RNA samples were reverse transcribed with anchoring oligonucleotide primers and then amplified by the polymerase chain reaction (PCR) with additional upstream random primers. Differentially expressed complementary DNA (cDNA) products were subsequently used as probes in Northern blot analysis. One such cDNA product, present in tumor but absent in normal displays, showed identity with the adhesion molecule integrin alpha 6. In Northern blots of 16 HCC pairs, the ∼5.5 kb signal of integrin alpha 6 mRNA was overexpressed in seven tumors, with a weak signal in the normal livers. For those patients with versus without integrin alpha 6 mRNA overexpression: (1) grade III (or IV) histology was noted in seven of seven versus three of nine tumors, respectively (P = .03); (2) tumor recurrence or death (at mean follow‐up of 18 months) was noted in six of seven versus three of eight patients, respectively (P = .17). Similar results were obtained using semiquantitative PCR co‐amplification with glyceraldehyde 3‐phosphate dehydrogenase as a control; ±50% of the tumors had stronger integrin alpha 6 bands than their paired normals. Both A and B variants of integrin alpha 6 mRNA were detectable in the tumor and normal liver samples. The B variant was more pronounced than the A variant by 8.9‐fold in the tumors (n = 10) compared with threefold in the normal livers (n = 10), suggesting that the overexpression of integrin alpha 6 may be more reflective of abnormalities of B variant levels than of A variant levels. Important genes whose expression correlates with significant patient variables may be isolated by differential display; based on this small series there is a trend for integrin alpha 6 mRNA to be overexpressed in high‐grade HCC and to predict a tendency toward a poorer outcome. (Hepatology 1995; 22:1447–1455).
A survey exploring research perception of homeopathic undergraduate students in West Bengal, India

Background: Prioritizing undergraduate research is emphasized to develop critical analytical skills and thinking, independent writing, future clinical practice, enhanced employability, and improved research productivity. Despite far reaching consequences, research perception of homeopathic undergraduate students has barely been investigated to date. Poor participation of homeopathic undergraduates in research is reflected by a single MEDLINE indexed publication with adequate studentsâ€™ contribution in the last decade. We aimed to assess their knowledge and attitude towards research and to identify barriers towards successful conduct of research. Methods: Institutional cross-sectional survey was carried out during August-September, 2013 in the four Government undergraduate homeopathic schools in West Bengal, India involving 902 participants. A semi-structured questionnaire was developed for the purpose depending on earlier studies on medical undergraduates. 364 completed responses were analyzed in the end. Results: Study sample mostly spanned 18-25 years of age group (94%), belonged to urban families (44.8%), with no gender differences (almost 1:1) and no physicians in family (73.1%). Maximum complete responses were obtained from 3rd year students (61.5%) and students of Calcutta Homeopathic Medical College and Hospital (51.2%). In spite of willingness to participate and keeping a positive attitude towards research, current involvement, training, knowledge and awareness remained quite unsatisfactory. Lack of infrastructure was identified as the chief barrier towards research. Conclusion: Undergraduates had a positive attitude towards homeopathic research, but need a realistic understanding of the research process. Opportunities for research skill development are underdeveloped.
Isolation of Naturally Occurring Viruses of the Murine Leukemia Virus Group in Tissue Culture

A tissue culture cell system for isolation and identification of members of the murine leukemia virus group (the complement fixation for murine leukemia test) was modified to permit the isolation of naturally occurring virus from leukemic and normal mice. The important factors for increasing the sensitivity of the test were the use of National Institutes of Health (NIH) strain Webster Swiss embryo cell cultures and the selection of rat-immune sera having complement-fixing antibodies to tissue culture antigens of both the Gross and FMR subgroups. In all, 163 strains of mouse leukemia virus, from 11 inbred mouse strains, have been isolated. Representative virus isolates were shown to possess the properties of the murine leukemia virus group; i.e., they were chloroform-sensitive, noncytopathic agents which replicated in mouse embryo tissue culture and produced group-reactive, complement-fixing antigen and budding C-type particles visible by electron microscopy. These viruses could serve as helpers in the rescue of Moloney sarcoma virus genome from non-producer hamster sarcoma cells, yielding pseudotypes. All of the 19 field isolates tested were neutralized by Gross passage A antiserum but not by potent antisera to the Moloney, Rauscher, and Friend strains. Virus was recovered regularly from embryos and from the plasma and spleen of adult mice of high leukemic strains. In low leukemic mouse strains, different patterns of virus detection were observed. In C3H/He mice, virus was occasionally present in embryos and was found in 40% of adult spleens. BALB/c mice were virus-negative as fetuses or weanlings, but spleens of more than half of the mice over 6 months of age yielded virus. NIH mice have never yielded virus. In reciprocal matings between AKR and BALB/c mice, virus recovery from embryos was maternally determined. The development of tissue culture isolation procedures made possible for the first time the application of classical infectious disease methods to the study of the natural history of murine leukemia virus infection.
Infertility and venereal disease in cattle inseminated with semen containing bovine herpesvirus type 5

A group of 20 cows and heifers experienced poor conception rates and probable ovarian dysfunction after being artificially inseminated. When first examined, some showed signs of vulvovaginitis, with pustular, ulcerative lesions consistent with a herpesvirus infection. They had had no contact with bulls during the current breeding season. Bovine herpesvirus type 5 (BHV-5) was isolated from samples of frozen semen from the batch that had been used for the artificial insemination programme. BHV-5 was also isolated from the semen of a second apparently healthy bull during routine screening of its semen.
Ionic homeostasis in brain conditioning

Most of the current focus on developing neuroprotective therapies is aimed at preventing neuronal death. However, these approaches have not been successful despite many years of clinical trials mainly because the numerous side effects observed in humans and absent in animals used at preclinical level. Recently, the research in this field aims to overcome this problem by developing strategies which induce, mimic, or boost endogenous protective responses and thus do not interfere with physiological neurotransmission. Preconditioning is a protective strategy in which a subliminal stimulus is applied before a subsequent harmful stimulus, thus inducing a state of tolerance in which the injury inflicted by the challenge is mitigated. Tolerance may be observed in ischemia, seizure, and infection. Since it requires protein synthesis, it confers delayed and temporary neuroprotection, taking hours to develop, with a pick at 1–3 days. A new promising approach for neuroprotection derives from post-conditioning, in which neuroprotection is achieved by a modified reperfusion subsequent to a prolonged ischemic episode. Many pathways have been proposed as plausible mechanisms to explain the neuroprotection offered by preconditioning and post-conditioning. Although the mechanisms through which these two endogenous protective strategies exert their effects are not yet fully understood, recent evidence highlights that the maintenance of ionic homeostasis plays a key role in propagating these neuroprotective phenomena. The present article will review the role of protein transporters and ionic channels involved in the control of ionic homeostasis in the neuroprotective effect of ischemic preconditioning and post-conditioning in adult brain, with particular regards to the Na+/Ca2+ exchangers (NCX), the plasma membrane Ca2+-ATPase (PMCA), the Na+/H+ exchange (NHE), the Na+/K+/2Cl− cotransport (NKCC) and the acid-sensing cation channels (ASIC). Ischemic stroke is the third leading cause of death and disability. Up until now, all clinical trials testing potential stroke neuroprotectants failed. For this reason attention of researchers has been focusing on the identification of brain endogenous neuroprotective mechanisms activated after cerebral ischemia. In this context, ischemic preconditioning and ischemic post-conditioning represent two neuroprotecive strategies to investigate in order to identify new molecular target to reduce the ischemic damage.
Statins and the risk of Parkinson disease: an update on the controversy.

BACKGROUND Parkinson disease (PD) is the second most common neuro- degenerative disease and the number of affected patients is growing. Until now, information on either risk factors (genetic or environmental) or neuro- protective agents is still scarce. Recently, hydroxymethylglutary-coenzyme A reductase inhibitors have been related to protective as well as to potential harmful effects with regard to the development of a PD diagnosis. OBJECTIVE To give an overview and comment on the data available so far on this topic. METHODS Relevant literature was identified using a PubMed search of articles published up to October 2008. Search terms included: 'Parkinson disease', 'statins', and 'epidemiology'. Original articles were reviewed and relevant citations from these articles were also considered. RESULTS/CONCLUSION Results of the available observational studies were inconsistent with most studies reporting a protective effect of statins on the risk of PD. Others found no altered risk of PD in statin users compared to non-users or even an increased risk. Studies largely varied in size and analysis methods. Thus, comparison of the results is difficult. Until now, no definite conclusion on this topic can be made.
Probabilistic Sensing Model for Sensor Placement Optimization Based on Line-of-Sight Coverage

This paper proposes a probabilistic sensor model for the optimization of sensor placement. Traditional schemes rely on simple sensor behaviour and environmental factors. The consequences of these oversimplifications are unrealistic simulation of sensor performance and, thus, suboptimal sensor placement. In this paper, we develop a novel probabilistic sensing model for sensors with line-of-sight-based coverage (e.g., cameras) to tackle the sensor placement problem for these sensors. The probabilistic sensing model consists of membership functions for sensing range and sensing angle, which takes into consideration sensing capacity probability as well as critical environmental factors such as terrain topography. We then implement several optimization schemes for sensor placement optimization, including simulated annealing, limited-memory Broyden-Fletcher-Goldfarb-Shanno method, and covariance matrix adaptation evolution strategy.
Psychometric Data for a Farsi Translation of the Trait Meta-Mood Scale

This study examined the internal consistency, test-retest reliability, and construct validity of a Farsi version of the Trait Meta-Mood Scale, with a sample of 306 undergraduate students (123 men, 183 women) ages 18 to 51 years. Participants completed Farsi versions of the Trait Meta-Mood Scale, the Satisfaction with Life Scale, and the Depression Anxiety Stress Scale. Analysis confirmed the preliminary reliabilities and construct validity of the Trait Meta-Mood Scale.
Irradiation of accretion discs in active galactic nuclei due to the presence of a warm absorber

The presence of a warm absorber of considerable optical depth is seen in many AGN. We show that this medium may significantly affect the optical/UV spectrum of an AGN by backscattering a fraction of the total radiation flux towards the disc surface. We consider in detail the case in which the disc extends down to a marginally stable orbit, all the emission comes from the disc surface, and the scattering medium forms a cone around the symmetry axis. Disc irradiation results in a much flatter optical/UV continuum than is predicted by standard disc models. The effect depends both on the total optical depth of the warm absorber and on the specific density distribution of this medium, so analysis of the optical/UV continuum allows constraints to be obtained for the warm absorber that are complementary to those obtained from the soft X-ray data analysis. We give results for two example sources ‐ RE J1034+396 and PG 1211+143, and for the bluest composite quasar spectrum of Richards et al. obtained from the SDSS. Ke yw ords: accretion, accretion discs ‐ radiative transfer ‐ galaxies: active ‐ galaxies: Seyfert ‐ X-rays: galaxies.
Simulated Nitrogen Deposition Reduces CH4 Uptake and Increases N2O Emission from a Subtropical Plantation Forest Soil in Southern China

To date, few studies are conducted to quantify the effects of reduced ammonium (NH4 +) and oxidized nitrate (NO3 −) on soil CH4 uptake and N2O emission in the subtropical forests. In this study, NH4Cl and NaNO3 fertilizers were applied at three rates: 0, 40 and 120 kg N ha−1 yr−1. Soil CH4 and N2O fluxes were determined twice a week using the static chamber technique and gas chromatography. Soil temperature and moisture were simultaneously measured. Soil dissolved N concentration in 0–20 cm depth was measured weekly to examine the regulation to soil CH4 and N2O fluxes. Our results showed that one year of N addition did not affect soil temperature, soil moisture, soil total dissolved N (TDN) and NH4 +-N concentrations, but high levels of applied NH4Cl and NaNO3 fertilizers significantly increased soil NO3 −-N concentration by 124% and 157%, respectively. Nitrogen addition tended to inhibit soil CH4 uptake, but significantly promoted soil N2O emission by 403% to 762%. Furthermore, NH4 +-N fertilizer application had a stronger inhibition to soil CH4 uptake and a stronger promotion to soil N2O emission than NO3 −-N application. Also, both soil CH4 and N2O fluxes were driven by soil temperature and moisture, but soil inorganic N availability was a key integrator of soil CH4 uptake and N2O emission. These results suggest that the subtropical plantation soil sensitively responses to atmospheric N deposition, and inorganic N rather than organic N is the regulator to soil CH4 uptake and N2O emission.
Preoperative education addressing postoperative pain in total joint arthroplasty: Review of content and educational delivery methods

Objective: Evaluate content and educational delivery methods of preoperative education in total joint arthroplasties of the hip and knee (THA and TKA) addressing postoperative pain. Data sources: Systematic searches conducted on Biomed Central, BMJ.com, CINAHL, the Cochrane Library, NLM Central Gateway, OVID, ProQuest (Digital Dissertations), PsycInfo, PubMed/Medline, ScienceDirect, and Web of Science. Secondary searching (pearling) was undertaken. Data extraction: Data were extracted utilizing the participants, interventions, comparisons, and outcomes approach. Study selection: All randomized controlled trials (RCTs) evaluating the effect of preoperative education on postoperative pain in THA and TKA surgery were considered for inclusion. Limitations: Studies published in English; published within the last 20 years and patients over the age of 18. No limitations were set on specific outcome measures of pain. Data synthesis: This review included 13 RCTs involving a total of 1,017 subjects who underwent THA or TKA. Educational delivery methods comprised verbal one-on-one or group education sessions, delivered within 4 weeks of surgery lasting an average of 30 minutes, and accompanied by other written materials. The educational content centered on descriptions of preoperative preparation, hospital stay, surgical procedure, immediate/intermediate experiences, expectations following surgery, rehabilitation, encouragement/reassurance, and answering common question associated with the surgical experience. Conclusions: Preoperative education centered on a biomedical model of anatomy and pathoanatomy as well as procedural information has limited effect in reducing postoperative pain after THA and TKA surgeries. Preoperative educational sessions that aim to increase patient knowledge of pain science may be more effective in managing postoperative pain.
Streamlining the continual flow processor architecture with fast replay loop

We present a streamlined continual flow processor architecture for scheduling instructions behind loads that miss the data cache. Instructions that do not encounter cache misses execute quickly, releasing their allocated hardware resources for other instructions. Instructions that depend on data cache misses wait in their reservation stations for the data, as long as the reservation station resources are not full. If the reservation stations become full blocking the pipeline, instructions dependent on cache misses give back their reservation stations and move directly into a large single-ported SRAM waiting buffer without having to go through pseudo execution and commit in the reorder buffer, as required by previous continual flow architectures. Afterwards, when the miss data cache block is fetched, these instructions are replayed from the waiting buffer, i.e., re-inserted again into the reservation stations to be scheduled for execution. Shortening the replay loop by removing the reorder buffer and the pseudo execute and commit from the replay path, improves performance on benchmarks with large number of loads that miss the L1 but hit the on-chip L2 data cache. Performance measurements using the SimpleScalar microarchitecture simulator and Spec 2006 benchmarks show that our streamlined continual flow pipeline architecture outperforms conventional continual flow pipeline architecture by 16% on average.
Relationships between psychological stress, coping and disordered eating: A review

Abstract Objective: Psychological stress and inadequate coping skills have been hypothesized to play important roles in the etiology of disordered eating. This paper reviews the empirical evidence which has emerged regarding the proposed relationships among stress. coping skills and various forms of disordered eating. Method: A search of psychological and medical databases was conducted to identify studies examining life events, and other types of psychological stress and coping strategies, in relation to the onset of disordered eating. Results: Despite methodological limitations such as the use of non-representative samples and retrospective methodologies, evidence of relationships between stress. coping and disordered eating was obtained in the majority of studies reviewed. Discussion: The implications of these findings am discussed and suggestions for future research, including the utilization of longitudinal. prospective studies, am presented.
Transitional fossils and the origin of turtles

The origin of turtles is one of the most contentious issues in systematics with three currently viable hypotheses: turtles as the extant sister to (i) the crocodile–bird clade, (ii) the lizard–tuatara clade, or (iii) Diapsida (a clade composed of (i) and (ii)). We reanalysed a recent dataset that allied turtles with the lizard–tuatara clade and found that the inclusion of the stem turtle Proganochelys quenstedti and the ‘parareptile’ Eunotosaurus africanus results in a single overriding morphological signal, with turtles outside Diapsida. This result reflects the importance of transitional fossils when long branches separate crown clades, and highlights unexplored issues such as the role of topological congruence when using fossils to calibrate molecular clocks.