Miracle-dz/UniFAR-FTUs huggingface dataset:
Expression Pattern Implicates a Potential Role for Luman Recruitment Factor in the Process of Implantation in Uteri and Development of Preimplantation Embryos in Mice

Abstract Luman/CREB3 recruitment factor (LRF or CREBRF) was identified as a regulator of Luman (or CREB3) that is involved in the unfolded protein response during endoplasmic reticulum stress. Luman is implicated in a multitude of functions ranging from viral infection and immunity to cancer. The biological function of LRF, however, is unknown. In this paper, we report that uteri of pregnant mice and embryos displayed enhanced LRF expression at all stages, and the expressed LRF was found to be localized specifically at implantation sites. On the other hand, uteri of mice induced for delayed implantation or pseudopregnant mice showed low levels of LRF expression, suggesting that LRF mediates uterine receptivity during implantation. Further, expression of LRF was found to be modulated by steroid hormones such as progesterone and estradiol. This study thereby identifies a potential role for LRF in the process of implantation in uteri and development of preimplantation embryos in mice.
On the volume conjecture for classical spin networks

We prove an upper bound for the evaluation of all classical SU(2) spin networks conjectured by Garoufalidis and van der Veen. This implies one half of the analogue of the volume conjecture which they proposed for classical spin networks. We are also able to obtain the other half, namely, an exact determination of the spectral radius, for the special class of generalized drum graphs. Our proof uses a version of Feynman diagram calculus which we developed as a tool for the interpretation of the symbolic method of classical invariant theory, in a manner which is rigorous yet true to the spirit of the classical literature.
Rapidly evolving circularly polarized emission during the 1994 outburst of GRO J1655-40

We report the detection of circular polarization during the 1994 outburst of the Galactic microquasar GRO J1655-40. The circular polarization is clearly detected at 1.4 and 2.4 GHz, but not at 4.8 and 8.4 GHz, where its magnitude never exceeds 5 mJy. Both the sign and magnitude of the circular polarization evolve during the outburst. The time dependence and magnitude of the polarized emission can be qualitatively explained by a model based on synchrotron emission from the outbursts, but is most consistent with circular polarization arising from propagation effects through the relativistic plasma surrounding the object.
A systematic review and empirical study investigating the impact of maternal perinatal anxiety on mother-infant interaction at six-months postpartum and children's emotional problems at age three.

The presented thesis was completed by Sarah Rees for the Doctorate degree of Clinical Psychology (DClinPsy) at Cardiff University. The thesis title is ‘A systematic review and empirical study investigating the impact of perinatal anxiety on mother-infant interaction at six-months postpartum and children’s emotional problems at age three years’. This thesis was submitted on the 30th May 2017 and comprises three papers. Papers 1 and 2 have been prepared for submission to European Child and Adolescent Psychiatry. Paper 1 presents a systematic review on the evidence for the impact of perinatal anxiety on children’s emotional problems. A literature search was conducted and 14 studies were identified that satisfied inclusion criteria for the review. Whilst the findings of this review indicate that there is evidence for both maternal antenatal and postnatal anxiety having an adverse impact on child emotional outcomes, the evidence appears stronger for the negative impact of antenatal anxiety. Several methodological weaknesses make conclusions problematic and replication of findings is required to improve identification of at-risk parents and children with appropriate opportunities for intervention and prevention. Paper 2 presents an experimental study, which explores the role of antenatal and postnatal anxiety on children’s emotional problems at age three years. A sample of 186 women and their first-born children were followed from pregnancy to age three years postpartum. Mothers completed antenatal and postnatal anxiety measures. Maternal care-giving behaviour was assessed using observations of a mother-infant interaction task. At three years, the Child Behaviour Check List (CBCL) was administered to assess for children’s emotional problems. Results indicated that maternal antenatal anxiety and postnatal depression independently predicted higher reported emotional problems in children at age 3 years after controlling for postnatal anxiety and antenatal depression symptoms. Postnatal depression was found to partially mediate the association between antenatal anxiety and children’s emotional problems. Antenatal anxiety was associated with elevated maternal negative affect at 6 months postpartum. However, the association between antenatal anxiety and children’s elevated emotional problems at age 3 was not explained by maternal negative affect at 6 months postpartum. These data suggest that children’s emotional problems are adversely affected by maternal antenatal anxiety and postnatal depression. This has implications for targeting intervention or prevention in the antenatal period to prevent adverse emotional outcomes in children. Paper 3 is a critical reflection of the systematic review, the empirical paper and the research process as a whole. Strengths and limitations are discussed as well as clinical and research implications.
Interactive Phrases: Semantic Descriptionsfor Human Interaction Recognition

This paper addresses the problem of recognizing human interactions from videos. We propose a novel approach that recognizes human interactions by the learned high-level descriptions, interactive phrases. Interactive phrases describe motion relationships between interacting people. These phrases naturally exploit human knowledge and allow us to construct a more descriptive model for recognizing human interactions. We propose a discriminative model to encode interactive phrases based on the latent SVM formulation. Interactive phrases are treated as latent variables and are used as mid-level features. To complement manually specified interactive phrases, we also discover data-driven phrases from data in order to find potentially useful and discriminative phrases for differentiating human interactions. An information-theoretic approach is employed to learn the data-driven phrases. The interdependencies between interactive phrases are explicitly captured in the model to deal with motion ambiguity and partial occlusion in the interactions. We evaluate our method on the BIT-Interaction data set, UT-Interaction data set, and Collective Activity data set. Experimental results show that our approach achieves superior performance over previous approaches.
Emergency reversal of anticoagulation with a three-factor prothrombin complex concentrate in patients with intracranial haemorrhage.

BACKGROUND Intracranial haemorrhage is a serious and potentially fatal complication of oral anticoagulant therapy. Prothrombin complex concentrates can substantially shorten the time needed to reverse the effects of oral anticoagulants. The aim of this study was to determine the efficacy and safety of a prothrombin complex concentrate for rapid reversal of oral anticoagulant therapy in patients with intracranial haemorrhage. METHODS Patients receiving oral anticoagulant therapy and suffering from acute intracranial haemorrhage were eligible for this prospective cohort study if their International Normalised Ratio (INR) was higher than or equal to 2.0. The prothrombin complex concentrate was infused at doses of 35-50 IU/kg, stratified according to the initial INR. RESULTS Forty-six patients (25 males; mean age: 75 years; range 38-92 years) were enrolled. The median INR at presentation was 3.5 (range, 2-9). At 30 minutes after administration of the prothrombin complex concentrate, the median INR was 1.3 (range, 0.9-3), and the INR then declined to less than or equal to 1.5 in 75% of patients. The benefit of the prothrombin complex concentrate was maintained for a long time, since the median INR remained lower than or equal to 1.5 (median, 1.16; range, 0.9-2.2) at 96% of all post-infusion time-points up to 96 hours. No thrombotic complications or significant adverse events were observed during hospitalisation; six patients (13%) died, but none of these deaths was judged to be related to administration of the prothrombin complex concentrate. CONCLUSIONS Prothrombin complex concentrates are an effective, rapid and safe treatment for the urgent reversal of oral anticoagulation in patients with intracranial haemorrhage. Broader use of prothrombin complex concentrates in this clinical setting appears to be appropriate.
Utility of Quantitative Sensory Testing and Screening Tools in Identifying HIV-Associated Peripheral Neuropathy in Western Kenya: Pilot Testing

Background/Aim Neuropathy is the most common neurologic complication of HIV but is widely under-diagnosed in resource-constrained settings. We aimed to identify tools that accurately distinguish individuals with moderate/severe peripheral neuropathy and can be administered by non-physician healthcare workers (HCW) in resource-constrained settings. Methods We enrolled a convenience sample of 30 HIV-infected outpatients from a Kenyan HIV-care clinic. A HCW administered the Neuropathy Severity Score (NSS), Single Question Neuropathy Screen (Single-QNS), Subjective Peripheral Neuropathy Screen (Subjective-PNS), and Brief Peripheral Neuropathy Screen (Brief-PNS). Monofilament, graduated tuning fork, and two-point discrimination examinations were performed. Tools were validated against a neurologist's clinical assessment of moderate/severe neuropathy. Results The sample was 57% male, mean age 38.6 years, and mean CD4 count 324 cells/µL. Neurologist's assessment identified 20% (6/30) with moderate/severe neuropathy. Diagnostic utilities for moderate/severe neuropathy were: Single-QNS - 83% sensitivity, 71% specificity; Subjective-PNS-total - 83% sensitivity, 83% specificity; Subjective-PNS-max and NSS - 67% sensitivity, 92% specificity; Brief-PNS - 0% sensitivity, 92% specificity; monofilament - 100% sensitivity, 88% specificity; graduated tuning fork - 83% sensitivity, 88% specificity; two-point discrimination - 75% sensitivity, 58% specificity. Conclusions Pilot testing suggests Single-QNS, Subjective-PNS, and monofilament examination accurately identify HIV-infected patients with moderate/severe neuropathy and may be useful diagnostic tools in resource-constrained settings.
Working Paper Alfred P. Sloan School of Management Targeted Repurchases and Common Stock Returns Targeted Repurchases and Common Stock Returns Targeted Repurchases and Common Stock Returns

This study provides new evidence on the stock price effects of targeted repurchases. We find a statistically significant average decline In the stock ^ prices of repurchasing firms of-3.5% at the targeted repurchase announcement. But this decline is more than offset by stock price increases that are associated with the initial investment announcement and with other \ related intervening announcements. The average total abnormal return for our sample of 111 repurchasing firms is 7.4%. We also explore the cross-sectional behavior of the targeted repurchase stock returns and investigate subsequent control changes in repurchasing firms.
FIRST VERIFICATION OF SCIAMACHY'S ABSORBING AEROSOL INDEX PRODUCT

Some preliminary results about the verication and validation of SCIAMACHY’s Absorbing Aerosol Index (AAI) are presented. The operational AAI level 2 product of SCIAMACHY is compared to our own AAI algorithm, developed at KNMI. The operational product shows general agreement with the KNMI algorithm but both suer from large errors in reectancees, resulting in a large o-set. Also, the neglect of polarisation in the operational product introduces signican t errors. The Absorbing Aerosol Index (AAI) is a measure for the presence of dark (i.e. absorbing) aerosols in the Earth’s atmosphere. It is an operational (near-real time) SCIAMACHY level 2 product. It uses the Earth’s reectance at two wavelengths, which is determined by the Earth’s radiance, the solar irradiance, and the solar zenith angle. These are all SCIAMACHY level 1 products and as such the AAI can be used for verication of these level 1 products as well. The AAI is dened as AAI = 100
Violin pedagogy for finger and bow placement using augmented reality

Beginners need a long time before being able to play correctly violin. Learning the bowing technique appears to be a difficult task and retains most of the attention of beginners. Besides this point, the finger placement is also an important part of the learning but often under estimated. One difficulty is that the fingerboard of the violin does not have frets. In this on-going work, we present a marker-less augmented reality system that advises the novice players about their fingering and bowing. We display in real-time the virtual frets by tracking the violin with a depth camera. We also capture and recognize the note currently played to direct the placement of the bow on the strings.
Redundant Vasodilator Pathways Underlying Radial Artery Flow-Mediated Dilation Are Preserved in Healthy Aging

Background. Blocking nitric oxide (NO) and vasodilator prostanoids (PN) does not consistently reduce flow-mediated dilation (FMD) in young adults. The impact of aging on the contribution of NO and PG to FMD is unknown. Methods. FMD was measured in older adults (n = 10, 65 ± 3 y) after arterial infusion of saline, N(G)-monomethyl-L-arginine (L-NMMA), and ketorolac + L-NMMA. Data were compared to published data in young adults. Results. L-NMMA reduced FMD in older adults (8.9 ± 3.6 to 5.9 ± 3.7%) although this was not statistically significant (P = 0.08) and did not differ (P = 0.74) from the reduction observed in young adults (10.0 ± 3.8 to 7.6 ± 4.7%; P = 0.03). Blocking PN did not affect FMD in young or older adults. In older adults, L-NMMA reduced (n = 6; range = 36–123% decrease), augmented (n = 3; 10–122% increase), or did not change FMD (n = 1; 0.4% increase). After PN blockade, FMD responses were reduced (n = 2), augmented (n = 6), or unaffected (n = 1). Conclusions. NO or PN blockade did not consistently reduce FMD in healthy older adults, suggesting the existence of redundant vasodilator phenotypes as observed previously in young adults.
The new sample of giant radio sources: I. radio imaging, optical identification and spectroscopy of selected candidates

A new sample of very large angular size radio sources has been selected from the 1.4 GHz VLA surveys: FIRST and NVSS. This sample will be very useful for an observational constraint on the time evolution of double radio sources, especially their size, predicted by numerous analytical models of such evolution (cf. Introduction). In this paper we present radio and optical data for a large fraction of the sample sources. They are: high-frequency VLA maps with very weak radio cores detected, deep optical images showing the identified faint host galaxies not visible on the DSS images, and optical spectra of the identified galaxies brighter than about $R\approx 18.5$ mag taken with the McDonald Observatory 2.1 m telescope. For 15 galaxies (of which 4 do not belong to the complete sample) the redshift has been determined. In the result, 44 per cent of galaxies in the complete sample have redshift data (with one exception all redshifts are less than 0.33), of which 70 per cent have a linear size exceeding 1 Mpc. The photometric redshift estimates for other 11 galaxies with $19 {\rm mag}< R< 21.7$ mag ($0.3< z< 0.5$) predict their sizes much over 1 Mpc.
Coping with Stress or Losing Control? Facebook-induced Strains Among Emerging Adults as a Consequence of Escapism versus Procrastination

Facebook use has been associated with a number of negative effects on emerging adults’ academic performance and well-being. We propose two distinct modes of Facebook use that may each uniquely contribute to these Facebook-induced strains in users’ everyday lives: escapism and procrastination. Both have been investigated as drivers of negative effects of digital media use, yet there seems to remain some confusion about their respective conceptualizations. The results of a survey study among student Facebook users (N = 345) underline that while escapism can be understood as a dysfunctional avoidance coping response to negative life circumstances, procrastination refers to a self-regulatory failure rooted in low self-control. Both escapism and procrastination, however, are characterized by the selection of enjoyable content that provides substitute gratifications and serves as a distraction from negative stimuli and situations. Likewise, both modes of usage contributed to perceived Facebook-induced strains, underlining the unique detrimental effects of escapism and procrastination on emerging adults’ well-being.
Responses to including parents in teacher evaluation policy: A critical policy analysis

Abstract The intersection of development in family and school settings has been well established and education policies have begun to promote ways to bridge the two contexts (i.e. teacher evaluations). For this manuscript, authors focus on how teachers and principals used a state educator evaluation policy to position parents as authorities on education. We utilize a Critical Policy Analysis and provide findings based on a study of 12 districts implementing a new teacher evaluation policy in Connecticut. Directionality of the strategies used to implement the policy surfaced as having implications for how much authority districts and schools granted to parents. These findings yield lessons and questions for teachers regarding practice and how they may be asked to participate in policies that measure its value.
Limited Partner Performance and the Maturing of the Private Equity Industry

We evaluate the performance of limited partners' (LPs) private equity investments over time. Using a sample of 14,380 investments by 1,852 LPs in 1,250 buyout and venture funds started between 1991 and 2006, we find that the superior performance of endowment investors in the 1991-1998 period, documented in prior literature, is mostly due to their greater access to the top-performing venture capital partnerships. In the subsequent 1999-2006 period, endowments no longer outperform, and neither have greater access to funds that are likely to restrict access nor make better investment selections than other types of institutional investors. We discuss how these results are consistent with the general maturing of the industry, as private equity has transitioned from a niche, poorly understood area to a ubiquitous part of institutional investors' portfolios.
A New Dataset for Fine Grained Citation Field Extraction (Author's Manuscript)

Citation field extraction entails segmenting a citation string into its constituent parts, such as title, authors, publisher and year. Despite the importance of this task, there is a lack of well-annotated citation data. This paper presents a new labeled dataset for citation extraction that, in comparison to the previous standard dataset, exceeds four-times more data, supplies detailed nested labels rather than coarse-grained flat labels, and is derived from four different academic fields rather than one. We describe our new dataset in detail, and provide baseline experimental results from a state-of-the-art extraction method.
Ten Steps in Scale Development and Reporting: A Guide for Researchers

ABSTRACT Scale development involves numerous theoretical, methodological, and statistical competencies. Despite the central role that scales play in our predictions, scholars often apply measurement building procedures that are inconsistent with best practices. The defaults in statistical programs, inadequate training, and numerous evaluation points can lead to improper practices. Based on a quantitative content analysis of communication journal articles, scholars have improved very little in the communication of their scale development decisions and practices. To address these reoccurring issues, this article breaks down and recommends 10 steps to follow in the scale development process for researchers unfamiliar with the process. Furthermore, the present research makes a unique contribution by overviewing procedures scholars should employ to develop their dimensions and corresponding items. The overarching objective is to encourage the adoption of scale development best practices that yield stronger concepts, and in the long run, a more stable foundation of knowledge.
Data doxa: The affective consequences of data practices

This paper explores the embedding of data producing technologies in people's everyday lives and practices. It traces how repeated encounters with digital data operate to naturalise these entities, while often blindsiding their agentive properties and the ways they get implicated in processes of exploitation and governance. I propose and develop the notion of ‘data doxa’ to conceptualise the way in which digital data – and the devices and platforms that stage data – have come to be perceived in Western societies as normal, necessary and enabling. The ‘data doxa’ concept also accentuates the enculturation of many individuals into a data sharing habitus which frames digital technologies in simplistic terms as (a) panaceas for the problems associated with contemporary life, (b) figures of progress and convenience, and (c) mediums of knowledge, pleasure and identity. I suggest that three types of data-based relations contribute to the formation of this doxic sensibility: fetishisation, habit and enchantment. Each of these relations come to mediate public understandings of digital devices and the data they generate, obscuring the multifaceted nature and hidden depths of data and their propensity to double up as technologies of exposure and discipline. As a result of this situation, imaginative educational programs and revamped regulatory frameworks are urgently needed to inform individuals about the contribution of data to the leveraging of value and power in today's digital economies, but also to protect them from experiencing data-based harms.
The clustering evolution of distant red galaxies in the GOODS-MUSIC sample

Aims. We study the clustering properties of Distant Red Galaxies (DRGs) to test whether they are the progenitors of local massive galaxies. Methods. We use the GOODS-MUSIC sample, a catalog of ∼3000 Ks-selected galaxies based on VLT and HST observation of the GOODS-South field with extended multi-wavelength coverage (from 0.3 to 8 μm) and accurate estimates of the photometric redshifts to select 179 DRGs with J - Ks > 1.3 in an area of 135 sq. arcmin. Results. We first show that the J - Ks > 1.3 criterion selects a rather heterogeneous sample of galaxies, going from the targeted high-redshift luminous evolved systems, to a significant fraction of lower redshift (1 < z < 2) and less luminous dusty starbursts. These low-redshift DRGs are significantly less clustered than higher-z DRGs. With the aid of extreme and simplified theoretical models of clustering evolution, we show that it is unlikely that the two samples are drawn from the same population observed at two different stages of evolution. Conclusions. High-z DRGs likely represent the progenitors of the more massive and more luminous galaxies in the local Universe and might mark the regions that will later evolve into structures of intermediate mass, like groups or small galaxy clusters. Low-z DRGs, on the other hand, will likely evolve into slightly less massive field galaxies.