Miracle-dz/UniFAR-FTUs huggingface dataset:
Smoothed Analysis on Connected Graphs

The main paradigm of smoothed analysis on graphs suggests that for any large graph $G$ in a certain class of graphs, perturbing slightly the edge set of $G$ at random (usually adding few random edges to $G$) typically results in a graph having much “nicer” properties. In this work, we study smoothed analysis on trees or, equivalently, on connected graphs. Given an $n$-vertex connected graph $G$, form a random supergraph $G^*$ of $G$ by turning every pair of vertices of $G$ into an edge with probability $\frac{\varepsilon}{n}$, where $\varepsilon$ is a small positive constant. This perturbation model has been studied previously in several contexts, including smoothed analysis, small world networks, and combinatorics. Connected graphs can be bad expanders, can have a very large diameter, and can possibly contain no long paths. In contrast, we show that if $G$ is an $n$-vertex connected graph, then typically $G^*$ has edge expansion $\Omega(\frac{1}{\log n})$, diameter $O(\log n)$, and vertex expansion $\Ome.
A Contention-Free Packet Scheduling Scheme for Provision of Quality-of- Service in Tbit/sec WDM Networks

Guaranteed Quality-of-Service (QoS) is a predominant requirement from modern high-performance switches and routers. Such devices are expected to support a large number of ports at high line rates carrying traffic with diverse statistical properties. In this paper a scheduling scheme for high-performance WDM packet-switch networks is presented. The proposed architecture is contention-free, scalable, easy to implement and requires no internal "speedup". Moreover, the scheme inherently supports the provision of per-class QoS. Non-uniform destination distribution and bursty cell arrivals are studied for a switch with an aggregated throughput of 1 Tbit/sec. Simulation results show that class-differentiated low latency is achieved, yielding a powerful solution for high-performance packet-switch networks.
Understanding Mexican‐American Marriage Patterns Using a Life‐Course Approach*

Objective. Guided by a life‐course framework that incorporates the interconnection between marriage, migration, and other transitions, we critically examine the familism explanation for the earlier age at marriage among Mexican Americans. Methods. We compare the marriage patterns of Mexican immigrants derived from the National Survey of Family Growth (NSFG) to those of women living in Mexico derived from the Mexican Census. We then use data from the NSFG to estimate proportional hazard models of marriage using fixed variables such as parent's education and time‐varying variables such as school enrollment. Results. Analyses show that the Mexican immigrant population marries earlier than Mexicans who do not migrate to the United States. In addition, the U.S.‐born Mexican population has lower marriage rates than whites once family background characteristics associated with early marriage are controlled and Anglos are no less likely than Mexican Americans to marry in response to a pregnancy. Conclusion. We find reason to doubt that ethnic differentials are driven by a strong attachment to marriage, female chastity, and the “traditional” family. Although cultural factors may play an important role, researchers need to more carefully specify the aspects of Mexican culture that might encourage marriage and how these factors interrelate with economic and demographic constraints.
Percepción de la infidelidad de adultos en el Área Metropolitana de Buenos Aires

Se realizo un estudio exploratorio a 600 adultos del Area Metropolitana de Buenos Aires, vinculado con la infidelidad, tipificando la poblacion por medio de una taxonomia de respuestas emocionales con un cuestionario online. Segun estudios anteriores, y por el contrario que las mujeres, los hombres mostrarian reacciones celosas de tipo sexual y no emocional, ya que la infidelidad femenina podria conducir a la posibilidad de que tuvieran que mantener descendientes que no fueran geneticamente suyos. Las conductas se organizaron de acuerdo con la Perceptions of Dating Infidelity Scale, distinguiendo tres clases de respuestas: ambiguas, explicitas y las enganosas. Utilizando Chi cuadrado, se discuten las diferencias respecto a estas variables: la edad, el estado civil, el genero, nivel educativo y creencias religiosas.
Genetic Diversity and Population Structure of the Pelagic Thresher Shark (Alopias pelagicus) in the Pacific Ocean: Evidence for Two Evolutionarily Significant Units

There has been an increasing concern about shark overexploitation in the last decade, especially for open ocean shark species, where there is a paucity of data about their life histories and population dynamics. Little is known regarding the population structure of the pelagic thresher shark, Alopias pelagicus. Though an earlier study using mtDNA control region data, showed evidence for differences between eastern and western Pacific populations, the study was hampered by low sample size and sparse geographic coverage, particularly a lack of samples from the central Pacific. Here, we present the population structure of Alopias pelagicus analyzing 351 samples from six different locations across the Pacific Ocean. Using data from mitochondrial DNA COI sequences and seven microsatellite loci we found evidence of strong population differentiation between western and eastern Pacific populations and evidence for reciprocally monophyly for organelle haplotypes and significant divergence of allele frequencies at nuclear loci, suggesting the existence of two Evolutionarily Significant Units (ESU) in the Pacific Ocean. Interestingly, the population in Hawaii appears to be composed of both ESUs in what seems to be clear sympatry with reproductive isolation. These results may indicate the existence of a new cryptic species in the Pacific Ocean. The presence of these distinct ESUs highlights the need for revised management plans for this highly exploited shark throughout its range.
Event-Detection Algorithms for Low Sampling Nonintrusive Load Monitoring Systems Based on Low Complexity Statistical Features

One of the key techniques toward energy efficiency and conservation is nonintrusive load monitoring (NILM) which lies in the domain of energy monitoring. Event detection is a core component of event-based NILM systems. This paper proposes two new low-complexity and computationally fast algorithms that detect the variations of load data and return the time occurrences of the corresponding events. The proposed algorithms are based on the phenomenon of a sliding window (SW) that tracks the statistical features of the acquired aggregated load data. The performance of the proposed algorithms is evaluated using real-world data and a comparative analysis has been carried out with one of the recently proposed event detection algorithms. Based on the simulations and sensitivity analysis, it is shown that the proposed algorithm can provide the results of up to 93% and 88% in terms of recall and precision, respectively.
Paroxetine Increased the Serum Estrogen in Postmenopausal Women with Depressive and Anxiety Symptoms

Objective: Both of selective serotonin reuptake inhibitors (SSRIs) and estrogen can modulate emotion and cognition function in post-menopause women, moreover SSRIs can influence estrogen system in rats and aquatic wildlife but most of them for reproductive ability. The aim of this study was to investigate the possible relationship between SSRI, estrogen, and emotion and cognition in post-menopause women with anxiety and depressive symptoms . Methods: A double-blind, randomized controlled trials of Paroxetine, an SSRI (n = 44), versus placebo (n = 38) for 6 months in post-menopausal women with anxiety and depressive symptoms. For screening anxiety, depression and mild cognitive impairment (MCI), we use the Hamilton Anxiety Rating Scale (HAM-A), the Hamilton Depression Rating Scale (HAM-D) and the Chinese Version of the Montreal cognitive assessment (MoCA-CV). And sex hormones were measured by ELASE method which is serum estradiol (E2), follicle stimulating hormone (FSH) and luteinizing hormone (LH). Results: Paroxetine increased serum E2 and decreased LH, FSH significantly (P < 0.05). Meanwhile, HAM-A and HAM-D scores declined and MoCA-CV score raised by Paroxetine (P < 0.05). We also found that a negative association between E2 and scores of HAM-A and HAM-D at pre-treatment and post-treatment of Paroxetine (HAM-A: R = ? 0.27, R = ? 0.24; HAM-D: R = ? 0.65, R = ? 0.37), while a positive correlation between E2 and MoCA-CV scores (R = 0.52, R = 0.47). Conclusions: This founding suggests that SSRI can increase serum estrogen levels and the change of estrogen may be one of mechanism in SSRI’s improve emotion and cognitive function in post-menopausal women.
An Analysis of Texas High School Counselors’ Roles: Actual and Preferred Counseling Activities

The purpose of our investigation was to explore the differences between the actual and preferred activities of high school counselors in Texas using the School Counselor Activity Rating Scale [SCARS] (Scarborough, 2002). Evident in the results was that the majority of high school counselors participating in our study have between 10–20 years of experience, work in suburban areas, and are Caucasian. Further, counselors reported that they actually engage in less counseling, consultation, curriculum, and coordination activities than they would prefer. Additionally, counselors with more than 10–20 years of experience reported more counseling activities than those with less, and Hispanic counselors prefer to do more counseling than Caucasian counselors. Implications for research and training programs are noted.
Antileishmanial and antitrypanosomal activity of symmetrical dibenzyl-substituted α,β-unsaturated carbonyl-based compounds

Background: Human African Trypanosomiasis (HAT) and leishmaniasis are two of the most neglected challenging tropical diseases, caused by the kinetoplastid parasites Trypanosoma and Leishmania species, respectively. For both of these complex disease spectra, treatment options are limited and threatened by drug resistance, justifying urgent new drug discovery efforts. Purpose: In the present study we investigated the antitrypanosomal and antileishmanial activity of a series of 21 symmetrical α,β-unsaturated carbonyl-based compounds, each featuring two 3-methoxybenzene attached to a central cyclohexanone, tetrahydro-4-pyranone scaffold or 4-piperidone ring. Structure-activity relationships were explored with respect to substitution on positions 3, 4 and 6 of the terminal 3-methoxybenzyl groups, and seven types of central ring. Results: Compounds 3a, 3o, 3s and 3t, showed broad anti-kinetoplastid activity against all species and strains tested. Conclusion: Compound 3o featuring N-methyl-4-piperidone was found to be the most potent analog and therefore can serve as a potential lead for the development of new drug candidates for trypanosomiasis and leishmaniasis.
Performance of a dynamic channel allocation technique based on signal strength measures

We analyze a dynamic channel assignment mechanism which selects the full-duplex channel that provides the minimum sum of signal strength measures on both uplink and downlink channels. In a previous work such a mechanism has been shown able to provide a remarkably better reuse degree than the "optimal" fixed channel assignment algorithm. In this paper we improve the analysis considering the impact of call admission control policies on system efficiency and flexibility. We show that a call admission algorithm based on the same signal strength measures used for the selection slightly impairs the reuse efficiency, but allow the system to exploit traffic fluctuations.
Is Macroporosity Absolutely Required for Preliminary in Vitro Bone Biomaterial Study? A Comparison between Porous Materials and Flat Materials

Porous materials are highly preferred for bone tissue engineering due to space for blood vessel ingrowth, but this may introduce extra experimental variations because of the difficulty in precise control of porosity. In order to decide whether it is absolutely necessary to use porous materials in in vitro comparative osteogenesis study of materials with different chemistries, we carried out osteoinductivity study using C3H/10T1/2 cells, pluripotent mesenchymal stem cells (MSCs), on seven material types: hydroxyapatite (HA), α-tricalcium phosphate (α-TCP) and β-tricalcium phosphate (β-TCP) in both porous and dense forms and tissue culture plastic. For all materials under test, dense materials give higher alkaline phosphatase gene (Alp) expression compared with porous materials. In addition, the cell density effects on the 10T1/2 cells were assessed through alkaline phosphatase protein (ALP) enzymatic assay. The ALP expression was higher for higher initial cell plating density and this explains the greater osteoinductivity of dense materials compared with porous materials for in vitro study as porous materials would have higher surface area. On the other hand, the same trend of Alp mRNA level (HA > β-TCP > α-TCP) was observed for both porous and dense materials, validating the use of dense flat materials for comparative study of materials with different chemistries for more reliable comparison when well-defined porous materials are not available. The avoidance of porosity variation would probably facilitate more reproducible results. This study does not suggest porosity is not required for experiments related to bone regeneration application, but emphasizes that there is often a tradeoff between higher clinical relevance, and less variation in a less complex set up, which facilitates a statistically significant conclusion. Technically, we also show that the base of normalization for ALP activity may influence the conclusion and there may be ALP activity from serum, necessitating the inclusion of “no cell” control in ALP activity assay with materials. These explain the opposite conclusions drawn by different groups on the effect of porosity.
Study of Hard and Soft Countermeasures for Scour Protection of the Jacket-Type Offshore Wind Turbine Foundation

Physical model tests with the scale of 1:36 are carried out in the Near-Shore Wave Basin (NSWB) at Tainan Hydraulics Laboratory (THL) with the jacket-type offshore wind turbine foundation (jacket-type foundation) and the combination of hard or soft scour protection in the test area. Scouring around the jacket-type foundation exposed to wave and current was conducted in the NSWB with a mobile bed experiment. Two locations (a water depth of 12 m and 16 m) of the foundations are separately simulated in this study. Based on the analysis from the former NSWB experimental results, one traditional hard scour protection usually used in Taiwan with four layers around the foundation is proposed for the mitigation of scouring. From the experimental results, a four-layer scour protection is tested and found to be effective in preventing scouring around the jacket-type foundation. Besides the hard scour protection countermeasure, the scour protection effect of an integrated offshore wind turbine and cage net aquaculture facility as a soft countermeasure for scour protection of the jacket-type foundation is further evaluated in this study. Meanwhile, a detailed analysis for stakeholders’ opinions on the integration of offshore wind farms and coastal aquaculture is also considered to obtain important experience and knowledge; and furthermore, to understand the real demand for adjusting the feasibility of this soft countermeasure.
A Boost for the Middle Class: An Evaluation of No-Loan Policies and Elite Private College Enrollment

ABSTRACT In response to goals of expanding access as well as public pressure to leverage substantial endowment resources toward increasing affordability, numerous elite colleges have enacted policies aimed at improving access and affordability by replacing student loans with grants in financial aid packages. No-loan policies, however, differ in the extent to which they expand affordability: Some policies offer a universal discount by replacing loans with grants for all aid-eligible students, while others offer narrowly targeted discounts to students based on income, Pell Grant eligibility status, or another means-tested threshold. We leveraged newly available Equality of Opportunity Project Mobility Report Card data and a difference-in-differences design using unweighted and weighted comparison groups to examine the relationship between adoption of universal and targeted no-loan policies and economic diversity at elite colleges. We found that colleges offering universal discounts experienced increased enrollment among middle-class students. Our study indicates universal no-loan policies represent one strategy to increase access and affordability for the middle-class in the elite reaches of higher education. The study also, however, raises questions about the policies’ effectiveness in addressing access for low-income students and efficiency in targeting aid.
HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3

Aims HMGB1 injection into the mouse heart, acutely after myocardial infarction (MI), improves left ventricular (LV) function and prevents remodeling. Here, we examined the effect of HMGB1 in chronically failing hearts. Methods and Results Adult C57 BL16 female mice underwent coronary artery ligation; three weeks later 200 ng HMGB1 or denatured HMGB1 (control) were injected in the peri-infarcted region of mouse failing hearts. Four weeks after treatment, both echocardiography and hemodynamics demonstrated a significant improvement in LV function in HMGB1-treated mice. Further, HMGB1-treated mice exhibited a ∼23% reduction in LV volume, a ∼48% increase in infarcted wall thickness and a ∼14% reduction in collagen deposition. HMGB1 induced cardiac regeneration and, within the infarcted region, it was found a ∼2-fold increase in c-kit+ cell number, a ∼13-fold increase in newly formed myocytes and a ∼2-fold increase in arteriole length density. HMGB1 also enhanced MMP2 and MMP9 activity and decreased TIMP-3 levels. Importantly, miR-206 expression 3 days after HMGB1 treatment was 4-5-fold higher than in control hearts and 20–25 fold higher that in sham operated hearts. HMGB1 ability to increase miR-206 was confirmed in vitro, in cardiac fibroblasts. TIMP3 was identified as a potential miR-206 target by TargetScan prediction analysis; further, in cultured cardiac fibroblasts, miR-206 gain- and loss-of-function studies and luciferase reporter assays showed that TIMP3 is a direct target of miR-206. Conclusions HMGB1 injected into chronically failing hearts enhanced LV function and attenuated LV remodelling; these effects were associated with cardiac regeneration, increased collagenolytic activity, miR-206 overexpression and miR-206 -mediated inhibition of TIMP-3.
Terminal osseous dysplasia with pigmentary defects (TODPD) due to a recurrent filamin A (FLNA) mutation

Terminal osseous dysplasia with pigmentary defects (TODPD) is an X‐linked dominant syndrome with distal limb anomalies, pigmentary skin defects, digital fibromas, and generalized bone involvement due to a recurrent mutation in the filamin A (FLNA) gene. We here report the mutation c.5217G>A in FLNA in three families with TODPD and we found possible germline and somatic mosaicism in two out of the three families. The occurrence of somatic and germline mosaicism for TODPD indicates that caution should be taken in counseling recurrence risks for these conditions upon presentation of an isolated case.
Cluster of differentiation 45 activation is crucial in interleukin-10-dependent tumor-associated dendritic cell differentiation

Tumor-associated dendritic cells (TADCs) are important in tumor immune surveillance, and it has been reported that the secretion of interleukin (IL)-10 by cancer cells is a major factor involved in the induction of TADCs in the tumor microenvironment. In the present study, IL-10 was found to activate cluster of differentiation (CD)45 protein tyrosine phosphatase (PTPase), inducing a TADC-like phenomenon. The PTPase inhibitor, phenylarsine oxide, and a CD45 inhibitor reversed the IL-10-induced impaired differentiation of the DCs, and also reversed the induction of the TADCs by A549, MDA-MB-231 and SW480 conditioned media, which thus represents a novel therapy to reduce immune surveillance in the tumor microenvironment. The present study is the first to identify that CD45 is involved in IL-10-activated signaling in myeloid lineage cells.
PEMBERDAYAAN PSIKOLOGI : HUBUNGANNYA DENGAN KEPUASAN KERJA DAN KOMITMEN AFEKTIF

The purpose of this research is to analyze the relationship between Psychological empowerment toward Job satisfaction and Affective commitment in Hasanah Graha Afiah Hospital, Depok. In this research, the researcher used descriptive statistic analysis and correlation coefficient in SPSS 11.5 software. Total sample of this research is 115 employees in this hospital. The conclution's result from this research is most of the gender that worked in Hasanah Graha Afiah Hospital is woman with total result with 82,6%, age from 24-26 years is 67,8%, and have been worked from 1-3 years is 46,1%. This research used hypotheses test toward every variable dimension through individual analysis based on any informations related to Psychological empowerment (mean score 3.89) toward Job satisfaction (mean score 3.85) and Affective commitment (mean score 3.92). Based on the relation analysis of Psychological empowerment toward Affective commitment and Job satisfaction showed that there was a significant relation between Psychological empowerment toward affective commitment and Job satisfaction with the Pearson Correlation's value for each relationship was 0.785 and 0.570. Keywords: Psychological empowerment, Affective commitment, Job satisfaction
LSD and AMAZE: the mass-metallicity relation at z > 3

Abstract We present the first results on galaxy metallicity evolution at z > 3 from two projects, LSD (Lyman-break galaxies Stellar populations and Dynamics) and AMAZE (Assessing the Mass Abundance redshift Evolution). These projects use deep near-infrared spectroscopic observations of a sample of ~40 LBGs to estimate the gas-phase metallicity from the emission lines. We derive the mass-metallicity relation at z > 3 and compare it with the same relation at lower redshift. Strong evolution from z = 0 and z = 2 to z = 3 is observed, and this finding puts strong constraints on the models of galaxy evolution. These preliminary results show that the effective oxygen yields do not increase with stellar mass, implying that the simple outflow model does not apply at z > 3.