Miracle-dz/UniFAR-FTUs huggingface dataset:
WATER SAVING UNDER ALTERNATIVE FURROWS SURFACE IRRIGATION IN CLAY SOILS OF NORTH NILE DELTA

Surface irrigation is the dominant method of on-farm irrigation in Egypt as well as world wide. Furrow watering is considered as one of the main types of surface irrigation. Most of the cultivated crops are grown under such type of watering. The principal advantage of furrow irrigation is the less irrigated area comparing with that under basin irrigation which equaled total cultivated acreage. Under the present situation of water shortage that facing Egypt resulted in capita share from water for different purposes becomes less than the water poverty edge and expected more decreasing to reach the scarcity level in the few coming decades. Moreover, Egypt is the solely country in the world that its agriculture is depending mainly on irrigation, i.e. irrigated agriculture due to the high arid condition of the country. For clay soils, the horizontal movement of irrigation water is exceeding the vertical downward movement. So, in this direction, a field trial in two seasons was conducted in North Nile Delta region to find out the impact of alternative surface irrigation on beet water relations. Comparing with the traditional furrow irrigation; fixed as well as exchangeable alternative surface irrigation effects on water saving, crop water productivity and on-farm irrigation efficiencies were analyzed.
Follicular lymphoma grade 3B is a distinct neoplasm according to cytogenetic and immunohistochemical profiles

Background According to the current World Health Organization Classification of Lymphoid Tumours, follicular lymphoma is subclassified into three grades according to the number of centroblasts. Follicular lymphoma grade 3 can be further divided into types A and B. Almost all available genetic data on grade 3B follicular lymphomas have been generated from tumors with an additional diffuse large B-cell lymphoma component. The purely follicular type of follicular lymphoma grade 3B is a rare neoplasm. Design and Methods We performed a detailed immunohistochemical (CD10, IRF4/MUM1, BCL2, Ig light chains) and genetic (translocations of BCL2, BCL6, MYC, IRF4) characterization of the largest series of purely follicular cases of grade 3B follicular lymphoma available to date, comprising 23 tumor samples. We also included 25 typical grade 1 or 2 follicular lymphomas, 9 follicular lymphomas with large centrocytes and/or high proliferation indices (FL/LCC), 12 cases of follicular lymphoma grade 3A, 16 cases of diffuse large B-cell lymphoma/follicular lymphoma grade 3B and 15 follicular lymphomas in which a straightforward distinction between grades 3A and 3B was not possible. Results Translocations affecting BCL2 and BCL6 genes are rare in grade 3B follicular lymphomas (2/23, 9% and 4/23, 17%) when compared with grade 1 or 2 follicular lymphomas (22/25, 88%, P<0.001 and 0/25, P<0.05), FL/LCC (7/9, 78%, P<0.001 and 2/9, 22%), grade 3A follicular lymphomas (7/12, 58%, P<0.01 and 2/12, 17%), unclassified grade 3 follicular lymphomas (6/15, 40% and 2/15, 13%) and diffuse large B-cell lymphoma/follicular lymphoma grade 3B (2/16, 13% and 8/16, 50%, P<0.05). MYC translocations were detected occasionally in FL/LCC, follicular lymphoma grade 3B, and diffuse large B-cell lymphoma/follicular lymphoma grade 3B (13%–22%), but not in grade 1, 2 or 3A follicular lymphomas (P<0.05 when compared with follicular lymphoma grade 3B). Both follicular lymphoma grade 3B and diffuse large B-cell lymphoma/follicular lymphoma grade 3B were enriched in samples with a CD10−IRF4/MUM1+ immunophenotype (8/19, 42% and 7/16, 44%), with the vast majority of them lacking BCL2 translocations. In contrast, 42/46 grade 1 or 2 follicular lymphomas, FL/LCC and grade 3A follicular lymphomas were CD10+ (91%) while 0/46 expressed IRF4/MUM1. None of the tumor samples tested with increased IRF4/MUM1-expression harbored a translocation of the IRF4 gene locus. Conclusions Our results show that grade 3B follicular lymphomas form a distinct category of follicular lymphomas with infrequent BCL2 and BCL6 translocations, while grades 1, 2 and 3A follicular lymphomas and FL/LCC display homogeneous features with frequent BCL2 translocations and a CD10+IRF4/MUM1− immunophenotype.
Academics’ perceptions of the challenges and barriers to implementing research-based experiences for undergraduates

ABSTRACT How can universities ensure that strategic aims to integrate research and teaching through engaging students in research-based experiences be effectively realised within institutions? This paper reports on the findings of a qualitative study exploring academics’ perceptions of the challenges and barriers to implementing undergraduate research. Academics were asked about perceived constraints and enablements, how they defined undergraduate research, the forms of undergraduate research used, and they were encouraged to provide examples. Perceived constraints included particular institutional policies and structures, academics’ mindsets and lack of skills and questions of time and money. It was found that different definitions of undergraduate research lead to different practices and varying opportunities for further development. This paper presents different forms of engagement in undergraduate research allied to these different definitions and it draws on interviewees’ ideas about what has been enabling in their context to suggest possible strategies for institutions to move forward.
Trends and Social Differences in Alcohol Consumption during the Postcommunist Transition in Lithuania

The aim of the study was to evaluate the trends and social differences in consumption of various types of alcoholic beverages in Lithuania over the postcommunist transition period (1994–2010). The data were obtained from nine nationally representative postal surveys of Lithuanian population aged 20–64 conducted every second year (n = 17154). Prevalence of regular (at least once a week) consumption of beer, wine, or strong alcoholic beverages and the amount of alcohol consumed per week were examined. Regular beer drinking as well as the amounts consumed increased considerably in both genders. The increase in regular consumption of strong alcohol was found among women. Sociodemographic patterning of regular alcohol drinking was more evident in women than in men. In women, young age and high education were associated with frequent regular drinking of wine and beer. Social differences in regular alcohol drinking should be considered in further development of national alcohol control policy in Lithuania.
Practical Fine-Grained Information Flow Control Using Laminar

Decentralized Information Flow Control (DIFC) is a promising model for writing programs with powerful, end-to-end security guarantees. Current DIFC systems that run on commodity hardware can be broadly categorized into two types: language-level and operating system-level DIFC. Language solutions provide no guarantees against security violations on system resources such as files and sockets. Operating system solutions mediate accesses to system resources but are either inefficient or imprecise at monitoring the flow of information through fine-grained program data structures. This article describes Laminar, the first system to implement DIFC using a unified set of abstractions for OS resources and heap-allocated objects. Programmers express security policies by labeling data with secrecy and integrity labels and access the labeled data in security methods. Laminar enforces the security policies specified by the labels at runtime. Laminar is implemented using a modified Java virtual machine and a new Linux security module. This article shows that security methods ease incremental deployment and limit dynamic security checks by retrofitting DIFC policies on four application case studies. Replacing the applications' ad hoc security policies changes less than 10% of the code and incurs performance overheads from 5% to 56%. Compared to prior DIFC systems, Laminar supports a more general class of multithreaded DIFC programs efficiently and integrates language and OS abstractions.
Extending Moore's Exhaustion Model: Including Further Dimensions of Burnout and Investigating Their Influence on Turnover Intention Among IT Professionals

This research focuses on burnout as a driver of turnover intention amongst IT professionals. We extend Moore's exhaustion model by including further dimensions of burnout into the model, namely depersonalization and reduced personal accomplishment. The effect of stressors on these dimensions and the original dimension of emotional exhaustion is investigated, as is their influence on turnover intention among IT professional. Results based on a data sample of 154 IT professionals show that not only emotional exhaustion but also depersonalization leads to turnover intention. This outcome cannot be neglected when trying to reduce turnover intention in an organization in order to maintain competitive advantages. Moreover, while the stressors suggested by Moore influence emotional exhaustion, they only slightly explain the dimensions of depersonalization and reduced personal accomplishment. This indicates that these two dimensions of burnout are caused by additional factors, which represents a research gap worth investigating in future research.
SSEES Centre for the Study of Comparative Economics Size Matters : Entrepre n eurial Entry and Government

We explore the country-specific institutional characteristics likely to influence an individual’s decision to become an entrepreneur. We focus on the size of the government, on freedom from corruption, and on ‘market freedom' defined as a cluster of variables related to protection of property rights and regulation. We test these relationships by combining country-level institutional indicators for 47 countries with working age population survey data taken from the Global Entrepreneurship Monitor. Our results indicate that entrepreneurial entry is inversely related to the size of the government, and more weakly to the extent of corruption. A cluster of institutional indicators representing ‘market freedom’ is only significant in some specifications. Freedom from corruption is significantly related to entrepreneurial entry, especially when the richest countries are removed from the sample but unlike the size of government, the results on corruption are not confirmed by country-level fixed effects models.
Design of Automation for Telerobots and the Effect on Performance, Operator Situation Awareness, and Subjective Workload

In this article we review and assess human-centered level of automation (LOA), an alternate approach to traditional, technology-centered design of automation in dynamic-control systems. The objective of human-controlled LOA is to improve human-machine performance by taking into account both operator and technological capabilities. Automation literature has shown that traditional automation can lead to problems in operator situation awareness (SA) due to the out-of-the (control) loop performance problem, which may lead to a negative impact on overall systems performance. Herein we address a standing paucity of research into LOA to deal with these problems. Various schemes of generic control system function allocations were developed to establish a LOA taxonomy. The functions allocated to a human operator, a computer, or both, included monitoring system variables, generating process plans, selecting an “optimal” plan and implementing the plan. Five different function allocation schemes, or LOAs, were empirically investigated as to their usefulness for enhancing telerobot system performance and operator SA, as well as reducing workload. Human participants participated in experimental trials involving a high fidelity, interactive simulation of a telerobot performing nuclear materials handling at the various LOAs. Automation failures were attributed to various simulated system deficiencies necessitating operator detection and correction to return to functioning at an automated mode. Operator performance at each LOA, and during the failure periods, was evaluated. Operator SA was measured using the Situation Awareness Global Assessment Technique, and perceived workload was measured using the NASA-Task Load Index. Results demonstrated improvements in human-machine system performance at higher LOAs (levels involving greater computer control of system functions) along with lower operator subjective workload. However, under the same conditions, operator SA was reduced for certain types of system problems and reaction time to, and performance during, automation failures was substantially lower. Performance during automation failure was best when participants had been functioning at lower, intermediate LOAs (levels involving greater human control of system functions). © 2000 John Wiley & Sons, Inc.
Neuropeptide Y Gene Polymorphisms Confer Risk of Early-Onset Atherosclerosis

Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, and functional analysis of NPY in early-onset CAD. In familial CAD (GENECARD, N = 420 families), we found increased microsatellite linkage to chromosome 7p14 (OSA LOD = 4.2, p = 0.004) in 97 earliest age-of-onset families. Tagged NPY SNPs demonstrated linkage to CAD of a 6-SNP block (LOD = 1.58–2.72), family-based association of this block with CAD (p = 0.02), and stronger linkage to CAD in the earliest age-of-onset families. Association of this 6-SNP block with CAD was validated in: (a) 556 non-familial early-onset CAD cases and 256 controls (OR 1.46–1.65, p = 0.01–0.05), showing stronger association in youngest cases (OR 1.84–2.20, p = 0.0004–0.09); and (b) GENECARD probands versus non-familial controls (OR 1.79–2.06, p = 0.003–0.02). A promoter SNP (rs16147) within this 6-SNP block was associated with higher plasma NPY levels (p = 0.04). To assess a causal role of NPY in atherosclerosis, we applied the NPY1-receptor–antagonist BIBP-3226 adventitially to endothelium-denuded carotid arteries of apolipoprotein E-deficient mice; treatment reduced atherosclerotic neointimal area by 50% (p = 0.03). Thus, NPY variants associate with atherosclerosis in two independent datasets (with strong age-of-onset effects) and show allele-specific expression with NPY levels, while NPY receptor antagonism reduces atherosclerosis in mice. We conclude that NPY contributes to atherosclerosis pathogenesis.
Optimal Resting-Growth Strategies of Microbial Populations in Fluctuating Environments

Bacteria spend most of their lifetime in non-growing states which allow them to survive extended periods of stress and starvation. When environments improve, they must quickly resume growth to maximize their share of limited nutrients. Cells with higher stress resistance often survive longer stress durations at the cost of needing more time to resume growth, a strong disadvantage in competitive environments. Here we analyze the basis of optimal strategies that microorganisms can use to cope with this tradeoff. We explicitly show that the prototypical inverse relation between stress resistance and growth rate can explain much of the different types of behavior observed in stressed microbial populations. Using analytical mathematical methods, we determine the environmental parameters that decide whether cells should remain vegetative upon stress exposure, downregulate their metabolism to an intermediate optimum level, or become dormant. We find that cell-cell variability, or intercellular noise, is consistently beneficial in the presence of extreme environmental fluctuations, and that it provides an efficient population-level mechanism for adaption in a deteriorating environment. Our results reveal key novel aspects of responsive phenotype switching and its role as an adaptive strategy in changing environments.
Building Buddhism in England: The Flourishing of a Minority Faith Heritage

Abstract From the earliest days of Buddhism in Britain, individuals and communities have sought out buildings to provide locations where they might practise and teach Buddhism. In this paper, we focus on this neglected area of the study of minority faith traditions in Britain. Our research, which was commissioned by Historic England, examines how Buddhist communities have used buildings and what this tells us about how a minority tradition is initially established and how it subsequently changes and develops. In this context, we suggest that buildings are more than bricks and mortar and provide a richly rewarding analytical lens to tell stories about migration, socio-economic status, religious diversity and integration and the complexity of processes around secularisation and religious change, as well shifting policy agendas in the UK that have begun to take faith seriously. This contributes to deepening the picture of the migration and adaptation of Buddhism and Buddhist practice across the globe.
Demand-Driven Train Schedule Synchronization for High-Speed Rail Lines

This paper addresses a new class of train scheduling problems with two interconnected high-speed rail lines under given and precise time-dependent origin-destination demand input. The proposed systematic schedule synchronization approach focuses on satisfying the requirements of transfer passengers from one rail line to another rail line. Aiming to minimize passenger waiting times at stations and crowding disutility in trains, a nonlinear optimization model for a single-line case is formulated to demonstrate the modeling framework of train scheduling problems. The model is then extended to a two-line case by explicitly taking into account the number of boarding and alighting passengers at the connection station. Using a state-space representation, a novel dynamic programming algorithm is designed to solve the single-line problem as a deterministic finite-state problem with sequential decisions. An integer coding-based genetic algorithm procedure is developed to solve the proposed model for general cases with two lines. A simplified real-world example illustrates that the designed schedule is beneficial to the through passengers and transfer passengers simultaneously.
Molecular signature of Epstein Barr virus-positive Burkitt lymphoma and post-transplant lymphoproliferative disorder suggest different roles for Epstein Barr virus

Epstein Barr virus (EBV) infection is commonly associated with human cancer and, in particular, with lymphoid malignancies. Although the precise role of the virus in the pathogenesis of different lymphomas is largely unknown, it is well recognized that the expression of viral latent proteins and miRNA can contribute to its pathogenetic role. In this study, we compared the gene and miRNA expression profile of two EBV-associated aggressive B non-Hodgkin lymphomas known to be characterized by differential expression of the viral latent proteins aiming to dissect the possible different contribution of such proteins and EBV-encoded miRNAs. By applying extensive bioinformatic inferring and an experimental model, we found that EBV+ Burkitt lymphoma presented with significant over-expression of EBV-encoded miRNAs that were likely to contribute to its global molecular profile. On the other hand, EBV+ post-transplant diffuse large B-cell lymphomas presented a significant enrichment in genes regulated by the viral latent proteins. Based on these different viral and cellular gene expression patterns, a clear distinction between EBV+ Burkitt lymphoma and post-transplant diffuse large B-cell lymphomas was made. In this regard, the different viral and cellular expression patterns seemed to depend on each other, at least partially, and the latency type most probably played a significant role in their regulation. In conclusion, our data indicate that EBV influence over B-cell malignant clones may act through different mechanisms of transcriptional regulation and suggest that potentially different pathogenetic mechanisms may depend upon the conditions of the interaction between EBV and the host that finally determine the latency pattern.
The First Detection of Near-Infrared CN Bands in Active Galactic Nuclei: Signature of Star Formation

We present the first detection of the near-infrared CN absorption band in the nuclear spectra of active galactic nuclei (AGNs). This feature is a recent star formation tracer, being particularly strong in carbon stars. The equivalent width of the CN line correlates with that of the CO at 2.3 μm as expected in stellar populations (SPs) with ages between ~0.2 and ~2 Gyr. The presence of the 1.1 μm CN band in the spectra of the sources is taken as unambiguous evidence of the presence of young/intermediate SPs close to the central source of the AGNs. Near-infrared bands can be powerful age indicators for star formation connected to AGNs, the understanding of which is crucial in the context of galaxy formation and AGN feedback.
Marketing strategy and the internet: An organizing framework

Competitive strategy is primarily concerned with how a business should deploy resources at its disposal to achieve and maintain defensible competitive positional advantages in the marketplace. Competitive marketing strategy focuses on how a business should deploy marketing resources at its disposal to facilitate the achievement and maintenance of competitive positional advantages in the marketplace. In a growing number of product-markets, the competitive landscape has evolved from a predominantly physical marketplace to one encompassing both the physical and the electronic marketplace. This article presents a conceptual framework delineating the drivers and outcomes of marketing strategy in the context of competing in this broader, evolving marketplace. The proposed framework provides insights into changes in the nature and scope of marketing strategy; specific industry, product, buyer, and buying environment characteristics; and the unique skills and resources of the firm that assume added relevance in the context of competing in the evolving marketplace.
Investigation of Zipf’s ‘law-of-meaning’ on Turkish corpora

Zipf's law-of-meaning states that the number of meanings of a word is related to its frequency. Words that are seen more frequently tend to have more meanings than the ones that are seen less frequently. This law, like the other Zipfian laws is consistent with the principal of least effort. In this study we hope to establish a basis for the number of meanings a word can attain in Turkish with respect to its frequency in a document. Zipfian parameters are derived from two Turkish corpora on which the meanings are labeled. It is hoped that the results of this study contributes in resolving ambiguity of word senses in Turkish.
Plasticity in memristive devices for spiking neural networks

Memristive devices present a new device technology allowing for the realization of compact non-volatile memories. Some of them are already in the process of industrialization. Additionally, they exhibit complex multilevel and plastic behaviors, which make them good candidates for the implementation of artificial synapses in neuromorphic engineering. However, memristive effects rely on diverse physical mechanisms, and their plastic behaviors differ strongly from one technology to another. Here, we present measurements performed on different memristive devices and the opportunities that they provide. We show that they can be used to implement different learning rules whose properties emerge directly from device physics: real time or accelerated operation, deterministic or stochastic behavior, long term or short term plasticity. We then discuss how such devices might be integrated into a complete architecture. These results highlight that there is no unique way to exploit memristive devices in neuromorphic systems. Understanding and embracing device physics is the key for their optimal use.