Miracle-dz/UniFAR-FTUs huggingface dataset:
Tumescentless endovenous radiofrequency ablation with local hypothermia and compression technique

Introduction Modern surgical management of chronic venous insufficiency is possible since the development of catheter-based minimally invasive techniques, including radiofrequency ablation (RFA) and the application of colour Doppler sonography. RFA technology requires the use of tumescent anaesthesia, which prolongs the operating time. Instilling tumescent anaesthesia percutaneously below the saphenous fascia is the steepest part of the learning curve. In our study, we compared operative and postoperative results of tumescentless RFA and RFA with tumescent anaesthesia, to investigate the necessity of tumescent anaesthesia. Methods A total of 344 patients with Doppler-confirmed great saphenous vein insufficiency underwent RFA between January and December 2012. Patients were divided into two groups according to anaesthetic management. Group 1 consisted of 172 patients: tumescent anaesthesia was given before the ablation procedure, and group 2 contained 172 patients: a local hypothermia and compression technique was used; no tumescent anaesthesia was administered. The visual analogue scale (VAS) was used and ecchymosis scores of the patients were recorded. Clinical examinations were performed at each visit and Doppler ultrasonography was performed in the first and sixth month. Results Mean ablation time was significantly lower in group 2 compared to group 1 (7.2 vs 18.9 min; p < 0.05). Skin burn and paresthesia did not occur. The immediate occlusion rate was 100% for both groups. No significant difference was found between the groups in terms of VAS and ecchymosis scores. All patients returned to normal activity within two days. The primary closure rate of group 1 was 98.2% and group 2 was 98.8% at six months, and there was no significant difference between the groups (p > 0.05). Conclusion Eliminating tumescent infusion is a desirable goal. Tumescentless endovenous RFA with local hypothermia and compression technique appears to be safe and efficacious. Our technique shortens the operation time and prevents patient procedural discomfort.
A Fast Computational Model of Analogical Retrieval (and Mapping)

Computational models of analogy have modelled memory as a set of disjoint, encapsulated, domains. We suggest that a more realistic model of analogy could be constructed if memory was modelled as one large data structure, without this assumption of disjoint domains. We further argue that the retrieval subprocess of analogy may not be independent of the mapping sub-process, and that both processes may well be governed by structural similarity. We describe a computational model of analogical retrieval and mapping which incorporates these three ideas; it models memory as one large data structure, models mapping and retrieval together, and uses structural similarity to govern matching. Retrieval in this system corresponds to the searching of the data structure for analogical matches to a supplied probe. We describe a fast, practical and efficient mechanism for such retrieval which we have implemented. We then present performance results for the algorithm, showing that the retrieval time is O(N). The variable N is a characteristic of the graph which is not dependent on the size of the graph.
Using Simulations to Evaluate the Effects of Recommender Systems for Learners in Informal Learning Networks

Drachsler, H. , Hummel, H. , & Koper, R. (2008). Using Simulations to Evaluate the Effects of Recommender Systems for Learners in Informal Learning Networks. Proceedings of the 2nd Workshop on Social Information Retrieval for Technology Enhanced Learning, SIRTEL’08 at the 3rd European Conference on Technology Enhanced Learning (EC-TEL 2008). September, 16-19, 2008, Maastricht, The Netherlands: CEUR Workshop Proceedings, VOL-382.
Langerhans cell histiocytosis: 37 cases in a single brazilian institution

Objectives To improve the level of 'definitive' diagnosis of Langerhans cell histiocytosis by immunohistochemical investigation of the CD1a surface antigen and to compare outcomes in respect to age, gender, stage of the disease, treatment response and level of diagnostic accuracy. Methods A retrospective study was carried out of 37 children and adolescents with possible Langerhans cell histiocytosis between 1988 and 2008. The diagnoses were revisited using immunohistochemical investigations for CD1a, S-100 and CD68 in an attempt to reach definitive diagnoses for all cases. Results Before the study, only 13 of 37 patients (35.1%) had a 'definitive' diagnosis; by the end of the study, this number rose to 25 patients (67.6%). All reviewed cases were positive for the CD1a antigen. Overall survival was 88.5%. Multisystem disease (Stage 2; n=19) and absence of response at the 6th week of therapy (n=5) were associated to significantly lower overall survival (p-value = 0.04 and 0.0001, respectively). All deaths occurred in patients with multisystem disease and organ dysfunction at diagnosis. Other potential prognostic factors were not significant. Reactivation episodes occurred in 75% of the patients with multisystem disease. Diabetes insipidus was the most common sequel (21.6%). Conclusion The level of diagnostic accuracy was increased through immunohistochemistry. The overall survival rate was similar to international multicentric studies. Multisystem disease and absence of response at six weeks of treatment were the most important unfavorable prognostic factors. The frequency of reactivation for patients with multisystem disease was higher than described in the literature, probably because maintenance chemotherapy was used only in two cases.
Generation of a flanking sequence-tag database for activation-tagging lines in japonica rice.

We have generated 47,932 T-DNA tag lines in japonica rice using activation-tagging vectors that contain tetramerized 35S enhancer sequences. To facilitate use of those lines, we isolated the genomic sequences flanking the inserted T-DNA via inverse polymerase chain reaction. For most of the lines, we performed four sets of amplifications using two different restriction enzymes toward both directions. In analyzing 41,234 lines, we obtained 27,621 flanking sequence tags (FSTs), among which 12,505 were integrated into genic regions and 15,116 into intergenic regions. Mapping of the FSTs on chromosomes revealed that T-DNA integration frequency was generally proportional to chromosome size. However, T-DNA insertions were non-uniformly distributed on each chromosome: higher at the distal ends and lower in regions close to the centromeres. In addition, several regions showed extreme peaks and valleys of insertion frequency, suggesting hot and cold spots for T-DNA integration. The density of insertion events was somewhat correlated with expressed, rather than predicted, gene density along each chromosome. Analyses of expression patterns near the inserted enhancer showed that at least half the test lines displayed greater expression of the tagged genes. Whereas in most of the increased lines expression patterns after activation were similar to those in the wild type, thereby maintaining the endogenous patterns, the remaining lines showed changes in expression in the activation tagged lines. In this case, ectopic expression was most frequently observed in mature leaves. Currently, the database can be searched with the gene locus number or location on the chromosome at http://www.postech. ac.kr/life/pfg/risd. On request, seeds of the T(1) or T(2) plants will be provided to the scientific community.
Four-Stage Audit Demonstrating Increased Uptake of HIV Testing in Acute Neurology Admissions Using Staged Practical Interventions

Background UK National Guidelines (UKNG) advise HIV testing in clinically indicated neurological presentations. We audited the impact of our practical strategies to increase uptake of HIV testing at a regional acute neurology admissions unit. Methods We audited HIV testing in 4 periods over 2 years: before we designed a UKNG-based “HIV testing in Neurology” protocol (“pre-protocol”); after dissemination of the protocol alone (“post-protocol”); post-protocol dissemination combined with both a tailored departmental admissions clerking proforma to prompt for HIV testing & consenting, and regular focussed tutorials to doctors on HIV testing in neurological patients (“post-proforma”); and finally one year after the post-proforma period (“+1 year”). We also looked at the total number of HIV tests sent from the unit during the two-year period. We assessed significance using Fisher’s exact test. Results 47.8% of all acute neurology non-stroke admissions were eligible for HIV testing during all the audit periods. Testing rates were as follows: pre-protocol 21.9%; post-protocol 36.6%; post-proforma 83.3%; and at +1 year 65.4% (p<0.05 for both post-protocol and +1 year when compared to pre-protocol). Documentation of consent for HIV testing improved from 25% to 67.6% with the HIV-tailored clerking proforma. The total number of HIV tests requested from the unit doubled in the post-proforma period compared to pre-protocol (p<0.05). Conclusion In conclusion: the combination of an HIV testing protocol, a tailored departmental clerking proforma and regular focussed teaching to doctors on indications for HIV testing led to a sustained increase in HIV testing uptake in our regional acute neurology admissions unit.
Implicit and Explicit Illusory Correlation as a Function of Political Ideology

Research has demonstrated that people who embrace different ideological orientations often show differences at the level of basic cognitive processes. For instance, conservatives (vs. liberals) display an automatic selective attention for negative (vs. positive) stimuli, and tend to more easily form illusory correlations between negative information and minority groups. In the present work, we further explored this latter effect by examining whether it only involves the formation of explicit attitudes or it extends to implicit attitudes. To this end, following the typical illusory correlation paradigm, participants were presented with members of two numerically different groups (majority and minority) each performing either a positive or negative behaviour. Negative behaviors were relatively infrequent, and the proportion of positive and negative behaviors within each group was the same. Next, explicit and implicit (i.e., IAT-measured) attitudes were assessed. Results showed that conservatives (vs. liberals) displayed stronger explicit as well as implicit illusory correlations effects, forming more negative attitudes toward the minority (vs. majority) group at both the explicit and implicit level.
Escape from Cubicle Nation: From Corporate Prisoner to Thriving Entrepreneur

Inspired by her successful blog of the same name, life coach Slim shows readers how to navigate the terrifying yet gratifying transition from corporate drone to entrepreneur. She strikes a perfect balance between emotional encouragement and practical advice: “Hating your job intensely,” she writes, “is not a business plan. ” What's here is: the nitty-gritty of getting a business off the ground, legal considerations, making the best use of social networking sites, the components of a business model, organized creative brainstorming, financial advice, shopping for self-paid insurance and benefits, and helpful anecdotes of real-life entrepreneurship. With her humorous insights into corporate life and an appealing no-nonsense yet empathic tone, Slim deals swiftly and incisively with anxiety, fear and hesitation. Readers will cheer as she teaches the tricks behind finding “what makes you purr”—what people will pay you to do, what you have a great passion for and what you are genetically encoded to do. This is a standout in the start-your-own business genre.
How do Money, Sex, and Stress Influence Marital Instability?

Follow this and additional works at: https://newprairiepress.org/jft Part of the Cognitive Behavioral Therapy Commons, Counseling Psychology Commons, Family, Life Course, and Society Commons, Finance and Financial Management Commons, Gender, Race, Sexuality, and Ethnicity in Communication Commons, Marriage and Family Therapy and Counseling Commons, Social Psychology Commons, and the Social Work Commons
Low-velocity fault-zone guided waves: Numerical investigations of trapping efficiency

Recent observations have shown that shear waves trapped within low-velocity fault zones may be the most sensitive measure of fault-zone structure (Li et al., 1994a, 1994b). Finite-difference simulations demonstrate the effects of several types of complexity on observations of fault-zone trapped waves. Overlying sediments with a thickness more than one or two fault-zone widths and fault-zone step-overs more than one or two fault widths disrupt the wave guide. Fault kinks and changes in fault-zone width with depth leave readily observable trapped waves. We also demonstrate the effects of decreased trapped wave excitation with increasing hypocentral offset from the fault and the effects of varying the contrast between the velocity in the fault zone and surrounding hard rock. Careful field studies may provide dramatic improvements in our knowledge of fault-zone structure.
The dissimilar costs of love and war: age‐specific mortality as a function of the operational sex ratio

Lifespan and ageing are strongly affected by many environmental factors, but the effects of social environment on these life‐history traits are not well understood. We examined effects of social interaction on age‐specific mortality rate in the sexually dimorphic neriid fly Telostylinus angusticollis. We found that although interaction with other individuals reduced longevity of both sexes, the costs associated with variation in operational sex ratio were sex specific: males’ early‐life mortality rate increased, and lifespan decreased, with increasing male bias in the sex ratio, whereas surprisingly, the presence of males had no effect on early‐life mortality or lifespan of females. Intriguingly, early‐life (immediate) mortality costs did not covary with late‐life (latent) costs. Rather, both sexes aged most rapidly in a social environment dominated by the opposite sex. Our findings suggest that distinct reproductive activities, such as mating and fighting, impose different age‐specific patterns of mortality, and that such costs are strongly sex specific.
The Statistical and Economic Role of Jumps in Continuous-Time Interest Rate Models

This paper analyzes the role of jumps in continuous-time short rate models. I first develop a test to detect jump-induced misspecification and, using Treasury bill rates, find evidence for the presence of jumps. Second, I specify and estimate a nonparametric jump-diffusion model. Results indicate that jumps play an important statistical role. Estimates of jump times and sizes indicate that unexpected news about the macroeconomy generates the jumps. Finally, I investigate the pricing implications of jumps. Jumps generally have a minor impact on yields, but they are important for pricing interest rate options. Copyright 2004 by The American Finance Association.
Ieee Transactions on Automatic Control Asymptotic Smooth Stabilization of the Inverted 3d Pendulum

—The 3D pendulum consists of a rigid body, supported at a fixed pivot, with three rotational degrees of freedom; it is acted on by gravity and it is fully actuated by control forces. The 3D pendulum has two disjoint equilibrium manifolds, namely a hanging equilibrium manifold and an inverted equilibrium manifold. The contribution of this paper is that two fundamental stabilization problems for the inverted 3D pendulum are posed and solved. The first problem, asymptotic stabilization of a specified equilibrium in the inverted equilibrium manifold, is solved using smooth and globally defined feedback of angular velocity and attitude of the 3D pendulum. The second problem, asymptotic stabilization of the inverted equilibrium manifold, is solved using smooth and globally defined feedback of angular velocity and a reduced attitude vector of the 3D pendulum. These control problems for the 3D pendulum exemplify attitude stabilization problems on the configuration manifold SO(3) in the presence of potential forces. Lyapunov analysis and nonlinear geometric methods are used to assess global closed-loop properties , yielding a characterization of the almost global domain of attraction for each case.
A scalable method for instance selection for class-imbalance datasets

Instance selection is becoming more and more relevant due to the huge amount of data that is constantly being produced. Research areas such as bioinformatics, text mining and intrusion detection, are generating huge amounts of information that must be dealt with. Instance selection is a powerful tool to reduce that information to manageable datasets. Most of the datasets in these areas shares a common property, they are heavily class-imbalanced. The class of interest, or positive or minority class, is outnumbered many times by the negative, or majority, class. Thus, any instance selection algorithm addressing these problems must take into account two important features of such problems. Firstly, the large size of the datasets that makes scalability issues very relevant. Secondly, the class-imbalanced distribution of the instances. In this paper, we propose a new methodology for instance selection that it is specifically designed for large class-imbalanced datasets. We use a divide-and-conquer approach to deal with the scalability of the algorithms, and a combination of different rounds of instance selection to improve the results in terms of class-imbalance error measures. The validity of the proposed framework is assured using 45 datasets. Our proposal improves the results of standard methods in accuracy and storage reduction, and at the same time is able to reduce the time needed by the algorithms with a time complexity O(n log(n)).
A Wireless Sensor Networks Based on Multi-angle Trust of Node

Facing the security threats and the energy shortage, a multi-angle trust mechanism for nodes in Wireless Sensor Networks was proposed, which extended the previous trust model only base on communication trust. With adding the sensing data and the node's energy in the factors of trust assessment, and new trust models to calculate the trust values of the sensed data and the node's energy, a more reliable wireless sensor networks could be established. Simulation experiment results show that, one model only based on communication trust is not enough to decide on the trustworthiness of a node. Hence we need to develop new techniques to combine the communication trust, data trust and energy trust into a unite trust.
Absorption and malabsorption of glycine and glycine peptides in man.

The 'glycine tolerance test', an oral dose of glycine followed by analysis of peripheral blood samples, was first used for investigating amino acid absorp- tion more than 30 years ago by Heath and Fullerton (1935), who, though they did not investigate any cases of unequivocal malabsorption, concluded that the test gave 'no useful information regarding the rate of absorption from the gastrointestinal tract'. Though the test has been used investigation of gastrointestinal disease, particularly tropical sprue, pancreatic insufficiency,
Impact on Pregnancies in South Brazil from the Influenza A (H1N1) Pandemic: Cohort Study

Introduction The emergence of a new subtype of the influenza virus in 2009 generated interest in the international medical community, the media, and the general population. Pregnant women are considered to be a group at risk of serious complications related to the H1N1 influenza virus. The aim of this study was to evaluate the outcomes and teratogenic effects of pregnancies exposed to the H1N1 virus during the Influenza A epidemic that occurred in the state of Rio Grande do Sul in 2009. Methods This is an uncontrolled prospective cohort study of pregnant women with suspected symptoms of Influenza A who were reported in the Information System for Notifiable Diseases – Influenza (SINAN-Influenza) during the epidemic of 2009 (database from the state of Rio Grande do Sul, Brazil). There were 589 cases of pregnant women with suspected infection. Among these, 243 were tested by PCR and included in the analysis. The main outcome measures were: maternal deaths, pregnancy outcome, stillbirths, premature births, low birth weight, congenital malformations, and odds ratios for H1N1+ and non-H1N1 pregnant women. Results There were one hundred and sixty-three (67%) confirmed cases of H1N1, 34 cases (14%) of seasonal Influenza A and 46 (19%) who were negative for Influenza A. There was no difference between the three groups in clinical parameters of the disease. There were 24 maternal deaths — 18 of them had H1N1. There were 8 stillbirths — 5 were children of H1N1 infected mothers. There were no differences in perinatal outcomes. Conclusions The present data do not indicate an increase in teratogenic risk from exposure to the influenza A (H1N1) virus. These results will help to strengthen the data and clarify the health issues that arose after the pandemic.
The Examination of Different Pathways Leading Towards Police Traumatization: Exploring the Role of Moral Injury and Personality in Police Compassion Fatigue

Police officers are mandated to respond to critical incidents, and, as the first responders to arrive at a crime scene, they are often tasked with providing support to traumatized victims of crimes. Compassion fatigue is a type of traumatization (“cost of caring”) experienced by caregiving professionals who work with traumatized populations (Figley, 1995). Conversely, compassion satisfaction refers to the sense of fulfillment that first responders feel from helping those who suffer (Stamm, 2002). The current research project is comprised of three studies. In study 1, researchers recruited a national police sample (n=1,351) from the US and Canada and measured the prevalence rates of compassion fatigue and satisfaction. This study found that authoritarianism was significantly associated with compassion fatigue among study participants. In study 2, the researcher further explored the role of negative personality traits (i.e., dark triad – Machiavellianism, narcissism, psychopathy) in a national sample (n=1,173) of police officers serving with the National Police of Finland. Study 2’s findings were consistent with those of Study 1, showing that negative personality traits were significantly associated with compassion fatigue among police officers. Study 3 built on the main findings of the first two studies, and aimed to identify the different pathways that lead to traumatization by examining moral injury’s role in the process. Moral injury refers to unprecedented traumatic life events, which can be understood as events wherein one perpetrates, fails to prevent, or bears witness to actions that “transgress deeply held moral beliefs and expectations” (Litz et al., 2009, p.1). Employing moral injury would enable researchers to examine the different mechanisms that lead to traumatization. To this end, study 3 recruited a sample (n=453) comprised of officers from the National Police of Finland and the results showed that the dark triad of personality significantly predicted “self-focused” and “others-focused” moral injury. In addition, “self-focused” moral injury (and not “others-focused” moral injury) significantly predicted compassion fatigue and Post-traumatic Stress Disorder (PTSD) symptoms. Furthermore, it was found that “self-focused” moral injury significantly mediated the pathway between dark triad personality traits and traumatization (compassion fatigue and PTSD symptoms). Clinical implications and recommendations for future research are discussed. Keywords: compassion fatigue, compassion satisfaction, moral injury, traumatization, negative personality traits, police.