Miracle-dz/UniFAR-FTUs huggingface dataset:
Wayward agents in a commuting scenario (personalities in the minority game)

In our daily lives we often have to face binary decisions where we seek to take the minority's choice, e.g., in traffic scenarios where we have to choose between similar alternative routes. We have studied agent coordination mechanisms in a binary decision model introduced in the literature, the minority game (Challet et al. (1998)). Extending this model, we introduced personalities which model certain types of human behaviour. Different populations of these personalities were simulated. It was found that there is one personality which performs better than the average: the wayward personality. We also extended the concept of Hamming distance to account for our personalities; this notion is useful for qualitatively explaining or predicting results. Our work gives insights into the impact of commuters' behaviours and it addresses relegated issues in traditional traffic simulation.
Critical Thinking Ability, L2 Vocabulary Knowledge, and L2 Vocabulary Learning Strategies

The purpose of the present study was to identify any significant relationship between critical thinking ability, L2 vocabulary knowledge, and L2 vocabulary learning strategies of Iranian EFL learners. To this aim, the productive vocabulary levels test was administered to measure the learner’s L2 vocabulary knowledge and observe homogeneity in terms of vocabulary knowledge. At the second stage, a critical thinking questionnaire was administered, along with a newly-developed L2 vocabulary learning strategies questionnaire; the questionnaires were developed to specify the critical thinking ability and L2 vocabulary learning strategies of the individual participants. The results of the statistical analysis revealed that Iranian EFL learners’ L2 vocabulary knowledge was significantly related to their critical thinking ability. The participants’ critical thinking ability also correlated positively with their self-assessed degree of determination, memorization, cognitive, and meta-cognitive strategies of L2 vocabulary learning. The study also showed a positive relationship between participants’ L2 vocabulary knowledge and their L2 vocabulary learning strategies.
The processing of coherent global form and motion patterns without visual awareness

In the present study we addressed whether the processing of global form and motion was dependent on visual awareness. Continuous flash suppression (CFS) was used to suppress from awareness global dot motion (GDM) and Glass pattern stimuli. We quantified the minimum time taken for both pattern types to break suppression with the signal coherence of the pattern (0, 25, 50, and 100% signal) and the type of global structure (rotational, and radial) as independent variables. For both form and motion patterns increasing signal coherence decreased the time required to break suppression. This was the same for both rotational and radial global patterns. However, GDM patterns broke suppression faster than Glass patterns. In a supplementary experiment, we confirmed that this difference in break times is not because of the temporal nature of GDM patterns in attracting attention. In Experiment 2, we examined whether the processing of dynamic Glass patterns were similarly dependent on visual awareness. The processing of dynamic Glass patterns is involves both motion and form systems, and we questioned whether the interaction of these two systems was dependent on visual awareness. The suppression of dynamic Glass patterns was also dependent on signal coherence and the time course of suppression break resembled the detection of global motion and not global form. In Experiment 3 we ruled out the possibility that faster suppression break times was because the visual system is more sensitive to highly coherent form and motion patterns. Here contrast changing GDM and Glass patterns were superimposed on the dynamic CFS mask, and the minimum time required for them to be detected was measured. We showed that there was no difference in detection times for patterns of 0 and 100% coherence. The advantage of highly coherent global motion and form patterns in breaking suppression indicated that the processing and interaction of global motion and form systems occur without visual awareness.
Adaptive De-Noising for PD Online Monitoring based on Wavelet Transform

White noise is a major noise that influences accuracy of partial discharge (PD) measurements. De-noising with wavelet shrinkage method is efficient for rejection of white noise. Thresholds of wavelet coefficients are key factors in close relation to the distortion and error of a de-noised PD signal. In this paper, a new thresholding function is introduced for estimating the optimal wavelet thresholds of noisy partial discharge signals. Several examples including two typical PD pulses are given. The de-noising results of four typical artificial signals and simulative noisy PD pulses indicate that the distortion degree and magnitude error of signals de-noised by the adaptive thresholding method are smaller than that of signals de-noised by soft thresholding method. An example of a field-detected PD signal shows the method is effective and practical in PD online monitoring
Detecting within- and between-day manifestations of neuromuscular fatigue at work: an exploratory study

Cumulative neuromuscular fatigue may result from exposure to physically demanding work, such as repetitive and/or sustained work with insufficient recovery. The aims of this exploratory study were to develop a battery of field usable fatigue measures and to document hand/arm fatigue in physically demanding work over multiple workdays and after a weekend break. Sixteen plumbers were observed for five days and measures of handgrip force, variability, tremor and discomfort were obtained pre-, mid- and post-shift. This exploratory study demonstrated increasing fatigue of the hand/arm over the day and persistent fatigue from Tuesday to Friday, and that a number of the measures did not return to baseline values following a weekend break. The findings provide preliminary evidence of cumulative fatigue in residential plumbing and insight into neuromuscular fatigue measurement. However, further work is needed to develop and refine a set of fatigue measures to detect neuromuscular fatigue at the workplace. Practitioner Summary: Cumulative fatigue has been linked to long-term health outcomes, including work-related musculoskeletal disorders. This paper presents findings from a physically demanding job (i.e. plumbing) revealing persistent fatigue over the work shift(s) and insufficient recovery after a weekend break, and provides insight into fatigue measurement at the workplace.
Non‐vitamin K antagonist oral anticoagulants (NOACs) in patients with concomitant atrial fibrillation and heart failure: a systemic review and meta‐analysis of randomized trials

No pooled analysis has been undertaken to assess the efficacy and safety of the non‐vitamin K antagonist oral anticoagulants (NOACs) compared with warfarin in the subgroup of patients with atrial fibrillation (AF) and heart failure (HF), including edoxaban data from recent randomized controlled trials (RCTs).
Interference-Aided Energy Harvesting: Cognitive Relaying With Multiple Primary Transceivers

We consider a spectrum sharing scenario where a secondary transmitter (ST) communicates with its destination via a decode-and-forward secondary relay (SR) in the presence of interference from multiple primary transmitters. The SR harvests energy from received radio-frequency signals that include primary interference and uses it to forward the information to the secondary destination. The relay adopts a time switching policy that switches between energy harvesting and information decoding over the time. Under the primary outage constraints and the peak power constraints at both ST and SR, to determine the average secondary throughput, we derive exact analytical expressions for the secondary outage probability and the ergodic capacity, which characterize the delay-limited and the delay-tolerant transmissions, respectively. We also investigate the effects of the number of primary transceivers and the peak power constraints on the optimal energy harvesting time that maximizes the secondary throughput. By utilizing the primary interference as an energy source, the secondary network achieves a better throughput performance compared to the case where the primary interference is ignored for energy harvesting purpose. Finally, we consider a case where ST also harvests energy from primary transmissions and compare its throughput performance with that of the non-energy harvesting ST case.
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

Invadopodia are matrix-degrading membrane protrusions in invasive carcinoma cells. The mechanisms regulating invadopodium assembly and maturation are not understood. We have dissected the stages of invadopodium assembly and maturation and show that invadopodia use cortactin phosphorylation as a master switch during these processes. In particular, cortactin phosphorylation was found to regulate cofilin and Arp2/3 complex–dependent actin polymerization. Cortactin directly binds cofilin and inhibits its severing activity. Cortactin phosphorylation is required to release this inhibition so cofilin can sever actin filaments to create barbed ends at invadopodia to support Arp2/3-dependent actin polymerization. After barbed end formation, cortactin is dephosphorylated, which blocks cofilin severing activity thereby stabilizing invadopodia. These findings identify novel mechanisms for actin polymerization in the invadopodia of metastatic carcinoma cells and define four distinct stages of invadopodium assembly and maturation consisting of invadopodium precursor formation, actin polymerization, stabilization, and matrix degradation.
Diagnostic approach to inborn errors of metabolism in an emergency unit

Objectives Our aim was to review the patients with a final diagnosis of inborn error of metabolism (IEM) who had previously required clinical attention at the emergency unit of our hospital over the last 9 years. Methods From the 184 patients with IEM, we selected 53 patients who required clinical attention at the EU as a prior step that led to a definitive diagnosis. We analyzed the frequency of the various IEM, their clinical presentations, and basic biochemical abnormalities in decompensation. Results We detected a predominance of neurologic signs (in 85% of our patients), followed by digestive symptoms (58.5%). Both were associated in 51% of patients. Vomiting and other digestive signs were observed in the same proportion as described in other series, but dehydration was only seen in three of our patients, probably because of early attention and fluid correction. Conclusions 1) the diagnosis of an IEM has often been made after the first consultation at the EU, leading to hospitalization; 2) we should suspect an IEM in patients with neurologic abnormalities (eg, developmental delay, hypotonus or feeding difficulties), especially in those patients with multisystem involvement who appear with acute symptoms; 3) it is of the greatest importance that the appropriate sample collection be made before starting any treatment, because abnormal biochemical data can yield a first approach and allow the definitive diagnosis; and 4) the diagnosis of a patient with an IEM is not based on a single clinical or biochemical data but rather on all abnormal features taken together.
Rifampin Drug Resistance Tests for Tuberculosis: Challenging the Gold Standard

ABSTRACT The rapid diagnosis of rifampin resistance is hampered by a reported insufficient specificity of molecular techniques for detection of rpoB mutations. Our objective for this study was to document the prevalence and prognostic value of rpoB mutations with unclear phenotypic resistance. The study design entailed sequencing directly from sputum of first failure or relapse patients without phenotypic selection and comparison of the standard retreatment regimen outcome, according to the mutation present. We found that among all rpoB mutations, the best-documented “disputed” rifampin resistance mutations (511Pro, 516Tyr, 526Asn, 526Leu, 533Pro, and 572Phe) made up 13.1% and 10.6% of all mutations in strains from Bangladesh and Kinshasa, respectively. Except for the 511Pro and 526Asn mutations, most of these strains with disputed mutations tested rifampin resistant in routine Löwenstein-Jensen medium proportion method drug susceptibility testing (DST; 78.7%), but significantly less than those with common, undisputed mutations (96.3%). With 63% of patients experiencing failure or relapse in both groups, there was no difference in outcome of first-line retreatment between patients carrying a strain with disputed versus common mutations. We conclude that rifampin resistance that is difficult to detect by the gold standard, phenotypic DST, is clinically and epidemiologically highly relevant. Sensitivity rather than specificity is imperfect with any rifampin DST method. Even at a low prevalence of rifampin resistance, a rifampin-resistant result issued by a competent laboratory may not warrant confirmation, although the absence of a necessity for confirmation needs to be confirmed for molecular results among new cases. However, a result of rifampin susceptibility should be questioned when suspicion is very high, and further DST using a different system (i.e., genotypic after phenotypic testing) would be fully justified.
The Dual Origin of the Yeast Mitochondrial Proteome

We propose a scheme for the origin of mitochondria based on phylogenetic reconstructions with more than 400 yeast nuclear genes that encode mitochondrial proteins. Half of the yeast mitochondrial proteins have no discernable bacterial homologues, while one‐tenth are unequivocally of α‐proteobacterial origin. These data suggest that the majority of genes encoding yeast mitochondrial proteins are descendants of two different genomic lineages that have evolved in different modes. First, the ancestral free‐living α‐proteobacterium evolved into an endosymbiont of an anaerobic host. Most of the ancestral bacterial genes were lost, but a small fraction of genes supporting bioenergetic and translational processes were retained and eventually transferred to what became the host nuclear genome. In a second, parallel mode, a larger number of novel mitochondrial genes were recruited from the nuclear genome to complement the remaining genes from the bacterial ancestor. These eukaryotic genes, which are primarily involved in transport and regulatory functions, transformed the endosymbiont into an ATP‐exporting organelle. Copyright © 2000 John Wiley & Sons, Ltd.
Instrumented Orthopaedics Analysis System

The system built consists of gait analysis system and gait recognition system. Gait analysis system is built attaching force sensing resistors into insole for foot analysis and wireless sensors are attached on ankle, kneecap (patella) and hip (pelvis) for lower extremity. Gait pattern recognition system is constructed using an embedded system with the capability of learning real time gait based on recurrent neural networks. In this investigation a systematic approach is undertaken to quantify the effects of varied interventions of legs and foot on the movement pattern of the lower extremity. Further, the relationship of these kinematics effects and the muscular activity of leg are analyzed. The prototype built is responsible to recognize features of orthopaedics issues of soccer players
Decentralized discovery of free parking places

This paper proposes a topology independent, scalable information dissemination algorithm for spatio-temporal traffic information such as parking place availability using vehicular ad hoc networks (VANET) based on Wireless-LAN IEEE 802.11. The algorithm uses periodic broadcasts for information dissemination. Broadcast redundancy is minimized by evaluation of application layer information and aggregation. Due to the spatio-temporal characteristics of parking place information, the spatial distribution of information is limited by utilizing techniques, which take the local relevance and age of information into account.Based on a realistic model of a german city with up to 10000 vehicles, our results show that a decentralized parking place information system works efficiently even with 5% of vehicles equipped with Wireless-LAN and without the help of any message relaying infrastructure. This fact makes such a non-safety driver assistance application very interesting, especially in the rollout phase of vehicular ad hoc networks.
A power model for routers: modeling Alpha 21364 and InfiniBand routers

As interconnection networks proliferate to many new applications, a low-latency high-throughput fabric is no longer sufficient. Applications are becoming power-constrained. We propose an architectural-level power model for interconnection network routers that will allow researchers and designers to easily factor in power when exploring architectural trade-offs. We applied our model to two commercial routers - the integrated Alpha 21364 router and the IBM 8-port 12X InfiniBand router and show that the different micro-architectures lead to vastly different power consumption and distribution estimates.
Hadzinia ferrani, sp. n. (Opiliones: Nemastomatidae), a highly specialized troglobiotic harvestman from Slovenia.

A highly specialized, endemic troglobiotic harvestman, Hadzinia ferrani sp. n. , recently found in the Ferranova buža cave in the karst of Mt. Ulovka in central Slovenia is described. It is characterized by its small, 1.1-1.4 mm long body and very long, thin appendages, with leg II more than 20-times as long as the body. Although very similar to Nemaspela Šilhavý, 1966, the genus Hadzinia Šilhavý, 1966 can be clearly differentiated from Nemaspela by its truncated glans and short stylus, well delimited from the glans. According to these characteristics, Hadzinia is assumed most closely related to Pyza Staręga, 1976 and Vestiferum Martens, 2006 rather than to Nemaspela with the glans gradually tapering into a mostly long stylus. Genital morphology is the most appropriate and probably the only morphological approach for investigating relationships among the taxa under study.
A Convex Framework for Fair Regression

We introduce a flexible family of fairness regularizers for (linear and logistic) regression problems. These regularizers all enjoy convexity, permitting fast optimization, and they span the rang from notions of group fairness to strong individual fairness. By varying the weight on the fairness regularizer, we can compute the efficient frontier of the accuracy-fairness trade-off on any given dataset, and we measure the severity of this trade-off via a numerical quantity we call the Price of Fairness (PoF). The centerpiece of our results is an extensive comparative study of the PoF across six different datasets in which fairness is a primary consideration.
Interactions between Oral Bacteria: Inhibition of Streptococcus mutans Bacteriocin Production by Streptococcus gordonii

ABSTRACT Streptococcus mutans has been recognized as an important etiological agent in human dental caries. Some strains of S. mutans also produce bacteriocins. In this study, we sought to demonstrate that bacteriocin production by S. mutans strains GS5 and BM71 was mediated by quorum sensing, which is dependent on a competence-stimulating peptide (CSP) signaling system encoded by the com genes. We also demonstrated that interactions with some other oral streptococci interfered with S. mutans bacteriocin production both in broth and in biofilms. The inhibition of S. mutans bacteriocin production by oral bacteria was stronger in biofilms than in broth. Using transposon Tn916 mutagenesis, we identified a gene (sgc; named for Streptococcus gordonii challisin) responsible for the inhibition of S. mutans bacteriocin production by S. gordonii Challis. Interruption of the sgc gene in S. gordonii Challis resulted in attenuated inhibition of S. mutans bacteriocin production. The supernatant fluids from the sgc mutant did not inactivate the exogenous S. mutans CSP as did those from the parent strain Challis. S. gordonii Challis did not inactivate bacteriocin produced by S. mutans GS5. Because S. mutans uses quorum sensing to regulate virulence, strategies designed to interfere with these signaling systems may have broad applicability for biological control of this caries-causing organism.
Flaws in Flynn Effect Research With the Wechsler Scales

Many Flynn effect (FE) studies compare scores across different editions of Wechsler’s IQ tests. When construct changes are introduced by the test developers in the new edition, however, the presumed generational effects are difficult to untangle from changes due to test content. To remove this confound, we use the same edition of Wechsler Intelligence Scale for Children–Fourth Edition (WISC-IV) across an 11-year period. Whereas previous research has reported the FE to be less than half the theoretical rate when comparing WISC-IV with Wechsler Intelligence Scale for Children–Fifth Edition (WISC-V), we find the rate of gain to be nearly identical to Flynn’s prediction when comparing only WISC-IV scores over the same time period. The FE is shown to vary significantly across the domains of cognitive ability, and thus changes to the construct coverage of the WISC-V Full Scale IQ (FSIQ) composite between editions significantly affect FE findings. Implications for future FE research are discussed.
Daptomycin, Fosfomycin, or Both for Treatment of Methicillin-Resistant Staphylococcus aureus Osteomyelitis in an Experimental Rat Model

ABSTRACT The in vivo activities of daptomycin, fosfomycin, and a combination of both antibiotics against a clinical isolate of methicillin-resistant Staphylococcus aureus (daptomycin MIC, 0.25 μg/ml; fosfomycin MIC, 0.5 μg/ml) were evaluated in a rat model of osteomyelitis. A total of 37 rats with experimental osteomyelitis were treated for 4 weeks with either 60 mg/kg of body weight of daptomycin subcutaneously once daily, 75 mg/kg fosfomycin intraperitoneally once daily, a combination of both drugs, or a saline placebo. After the completion of treatment, animals were euthanized, and the infected tibiae were processed for quantitative bacterial culture. Bone cultures were found to be positive for methicillin-resistant S. aureus in 9 of 9 (100%) animals of the placebo group, in 9 of 9 (100%) animals treated with daptomycin, in 1 of 10 (10%) fosfomycin-treated rats, and in 1 of 9 (22.2%) rats comprising the combination group. Results of bacterial counts in the bone samples were expressed as log10 CFU/g of bone and analyzed by using the Mann-Whitney U test followed by Bonferroni's multiple-comparison test. Based on bacterial counts, treatment with daptomycin was significantly superior to placebo, although it remained inferior to treatment with fosfomycin. No synergistic or antagonistic effect was observed for the combination therapy. No development of resistance against daptomycin or fosfomycin was observed after the 4-week treatment period.