Miracle-dz/UniFAR-FTUs huggingface dataset:
The Radish Gene Reveals a Memory Component with Variable Temporal Properties

Memory phases, dependent on different neural and molecular mechanisms, strongly influence memory performance. Our understanding, however, of how memory phases interact is far from complete. In Drosophila, aversive olfactory learning is thought to progress from short-term through long-term memory phases. Another memory phase termed anesthesia resistant memory, dependent on the radish gene, influences memory hours after aversive olfactory learning. How does the radish-dependent phase influence memory performance in different tasks? It is found that the radish memory component does not scale with the stability of several memory traces, indicating a specific recruitment of this component to influence different memories, even within minutes of learning.
Physical Simulation of Hot Rolling Steel Plate and Coil Production for Pipeline Applications

Within the techniques and equipments used to simulate industrial thermomechanical processing of High Strength Low Alloy (HSLA) pipeline steels, hot rolling laboratory mill equipped with cooling bed and coiling simulation furnace allows, not only accurate control of strains, temperatures, inter-pass times, and cooling rates but also enough amount of processed material for micro-structural characterisation and mechanical testing. Despite some differences with the industrial rolling, laboratory rolling offers a better simulation of the industrial rolling conditions than other thermo-mechanical simulators in terms of deformation mechanisms and processing constrains. This paper presents the results of simulation of different rolling schedules applied on pipeline grades in order to better understand the influence of the finishing rolling parameters namely: finish rolling temperature (FRT) and cooling routes on the microstructure and mechanical properties. It was observed that FRT and cooling rate have a strong impact on both grain refinement and precipitation behaviour, which leads to significant differences in strength and toughness. Furthermore variations of the above mentioned rolling parameters produce distinct fractions and distributions of austenite transformation products, variations in the final crystallographic texture and trigger diverse strengthening mechanisms (i.e. dislocation hardening). It was found that the accelerated cooling in a combination with a coiling simulation results in formation of microstructures with well developed low angle grain boundaries in comparison to the simulation made with air cooling. As a consequence the strength of the plates after accelerated cooling increases without changes in the Charpy impact toughness. It has been shown that the understanding of the effect of processing parameters on the microstructure of these steels is a key aspect for the optimization of their mechanical properties.
Min-capacity of a multiple-antenna wireless channel in a static Ricean fading environment

This paper presents the optimal guaranteed performance for a multiple-antenna wireless compound channel with M antennas at the transmitter and N antennas at the receiver on a Ricean fading channel with a static specular component. The channel is modeled as a compound channel with a Rayleigh component and an unknown rank-one deterministic specular component. The Rayleigh component remains constant over a block of T symbol periods, with independent realizations over each block. The rank-one deterministic component is modeled as an outer product of two unknown deterministic vectors of unit magnitude. Under this scenario, to guarantee service, it is required to maximize the worst case capacity (min-capacity). It is shown that for computing min-capacity, instead of optimizing over the joint density of T /spl middot/ M complex transmitted signals, it is sufficient to maximize over a joint density of min{T, M} real transmitted signal magnitudes. The optimal signal matrix is shown to be equal to the product of three independent matrices - a T /spl times/ T unitary matrix, a T /spl times/ M real nonnegative diagonal matrix, and an M /spl times/ M unitary matrix. A tractable lower bound on capacity is derived for this model, which is useful for computing achievable rate regions. Finally, it is shown that the average capacity (avg-capacity) computed under the assumption that the specular component is constant but random with isotropic distribution is equal to min-capacity. This means that avg-capacity, which, in general, has no practical meaning for nonergodic scenarios, has a coding theorem associated with it in this particular case.
Antinociceptive and neuropharmacological activities of methanol extract of Phoenix sylvestris fruit pulp

Fruits of Phoenix sylvestris Roxb. (Arecaceae) are used to treat back pain, toothache, headache, arthritis, nervous debility and as sedative. The aim of this study was to evaluate the antinociceptive and neuropharmacological activities of methanol extract of P. sylvestris fruit pulp (MEPS). The antinociceptive activity of MEPS was evaluated by heat-induced (hot plate, tail immersion test) and chemical-induced pain models (acetic acid-induced writhing, formalin-induced nociception, glutamate-induced nociception and paw edema test). The effect of MEPS on central nervous system (CNS) was studied using hole cross test, open field test, sodium thiopental-induced sleeping time and elevated plus maze test. MEPS showed strong, significant and dose-dependent antinociceptive activity in all heat-induced and chemical-induced pain models at all experimental doses. Involvement of opioid receptor mediated analgesia was evident from the reversal of analgesic effect by naloxone. MEPS also showed reduced locomotor activity in both hole cross and open field tests. The increase in sleeping time in sodium thiopental-induced sleeping test and anxiolytic activity in elevated plus maze test were also significant. So, it is evident that MEPS possesses strong central and peripheral antinociceptive activity as well as CNS depressant, sedative and anxiolytic activity. The results justify the ethnomedicinal use of P. sylvestris fruit in different painful conditions and CNS disorders.
Does Initial Shunt Type for the Norwood Procedure Affect Echocardiographic Measures of Cardiac Size and Function During Infancy?: The Single Ventricle Reconstruction Trial

Background— The Pediatric Heart Network trial comparing outcomes in 549 infants with single right ventricle undergoing a Norwood procedure randomized to modified Blalock-Taussig shunt or right ventricle–pulmonary artery shunt (RVPAS) found better 1-year transplant-free survival in those who received RVPAS. We sought to compare the impact of shunt type on echocardiographic indices of cardiac size and function up to 14 months of age. Methods and Results— A core laboratory measured indices of cardiac size and function from protocol exams: early after Norwood procedure (age 22.5±13.4 days), before stage II procedure (age 4.8±1.8 months), and at 14 months (age 14.3±1.2 months). Mean right ventricular ejection fraction was <50% at all intervals for both groups and was higher in the RVPAS group after Norwood procedure (49±7% versus 44±8%; P<0.001) but was similar by 14 months. Tricuspid and neoaortic regurgitation, diastolic function, and pulmonary artery and arch dimensions were similar in the 2 groups at all intervals. Neoaortic annulus area (4.2±1.2 versus 4.9±1.2 cm2/m2), systolic ejection times (214.0±29.4 versus 231.3±28.6 ms), neoaortic flow (6.2±2.4 versus 9.4±3.4 L/min per square meter), and peak arch velocity (1.9±0.7 versus 2.2±0.7 m/s) were lower at both interstage examinations in the RVPAS compared with the modified Blalock-Taussig shunt group (P<0.001 for all), but all were similar at 14 months. Conclusions— Indices of cardiac size and function after the Norwood procedure are similar for modified Blalock-Taussig shunt and RVPAS by 14 months of age. Interstage differences between shunt types can likely be explained by the physiology created when the shunts are in place rather than by intrinsic differences in cardiac function. Clinical Trial Registration— URL: http://www.clinicaltrials. gov. Unique identifier: NCT00115934.
Copy for all Pictures

A laboratory model of a holographic Instrument, es: entlally a logRlnp tool, has been designed and tested for measuring in-situ stress in a ^-inch diameter blind explcratory drill hole. Conceptually, the apparatus can ultimately operate remotely at depths of thousands of feet In a watersaturated environment. We have to date only tested it in a simulated borelole in the laboratory on prestressed samples (granite) which upon stress relief, in the simulated side walls, produced displacements >>n the order of . 3 '►jm. Power and controls for the instrument are at the surface. Data, in the form of holographic plates are stored, on board, the instrument. Displacement fields are stored in fringe patterns covering the holograph -ally recorded Images of the strained surface. The holographic instrument consists of separate co e drill, optics, and laser modular, and associated electrical and plumMng connections. The laboratory model incorporated many features of the field version. The performance of the holographic instrument in a dry and water-flooded simulated (concrete) borehole was excellent. Good quality holographic interferograms were obtained by double exposure, before and after drilling. In a water-flooded environment, of prestressed slabs of granite under loads in the 130 to 300 bar range. It is expected that this instrument will be able to resolve principal stresses as low as ~50 bars in dense indurated rocks (moduli -1 Mbar) and stresses on the order of 5 bars in softer sedimentarv rocks having insitu stresses as low as perhaps ~5 bars (assuming effective moduli of ^ 100 kbars). Applications of the instrument include: o Geothermal harnessing of energy from hot, dry rock. Knowledge of direction and magnitude of principal stresj will permit efficient fracturing of rock. o Estimating excavation costs for deep underground construction. o Determining stability of opening in deep rocks. o Discrimination of teleseismlc signals to determine their origin (earthquake or explosion). o Earthquake prediction.
A Hybrid Preference-Aware Recommendation Algorithm for Live Streaming Channels

With the advances of video streaming technology, live streaming services also become more and more popular. However, there may be thousands of online channels at the same time, and most viewers are not willing to go through one by one for finding the channels they are interested in. In view of this, we propose a hybrid preference-aware recommendation algorithm to recommend channels to viewers. We use logs of a live streaming service, Twitch. TV, to measure the performance of our algorithm and other existing algorithms, and experimental results show that the accuracy of our algorithm is higher than those of other algorithms.
Study on the Characteristics of New Abrasive Medium for Abrasive Flow Machining

Abrasive medium plays an important role in the application of abrasive flow machining (AFM), a process that finishes complex internal and external geometries. A new abrasive medium needs to be fabricated due to a lack of literature on it. In this work, a new abrasive medium was fabricated by using styrene butadiene rubber (SBR) as carrier and DF-101S was used to study its characterization. Results showed that new abrasive medium with good fluidity and temperature stability was obtained. Processing experiments have also been carried out by using new abrasive medium and MLLD60, and ZYGO was used to study the surface characteristics of the work-piece. Experimental results indicate that the new abrasive medium is applicable to AFM process.
A Comparative Study of Clinicopathological Features between Chronic Cholecystitis Patients with and without Helicobacter pylori Infection in Gallbladder Mucosa

Background Helicobacter pylori has been isolated from 10%–20% of human chronic cholecystitis specimens but the characteristics of “Helicobacter pylori positive cholecystitis” remains unclear. This study aims to compare the clinicopathological features between chronic cholecystitis patients with and without Helicobacter pylori infection in gallbladder mucosa. Methods Three hundred and twenty-six chronic cholecystitis patients were divided into two groups according to whether Helicobacter pylori could be detected by culture, staining or PCR for Helicobacter 16s rRNA gene in gallbladder mucosa. Positive samples were sequenced for Helicobacter pylori-specific identification. Clinical parameters as well as pathological characteristics including some premalignant lesions and the expression levels of iNOS and ROS in gallbladder were compared between the two groups. Results Helicobacter pylori infection in gallbladder mucosa was detected in 20.55% of cholecystitis patients. These patients had a higher prevalence of acid regurgitation symptoms (p = 0.001), more histories of chronic gastritis (p = 0.005), gastric ulcer (p = 0.042), duodenal ulcer (p = 0.026) and higher presence of Helicobacter pylori in the stomach as compared to patients without Helicobacter pylori infection in the gallbladder mucosa. Helicobacter pylori 16s rRNA in gallbladder and gastric-duodenal mucosa from the same individual patient had identical sequences. Also, higher incidences of adenomyomatosis (p = 0.012), metaplasia (p = 0.022) and higher enhanced expressions of iNOS and ROS were detected in Helicobacter pylori infected gallbladder mucosa (p<0.05). Conclusions Helicobacter pylori infection in gallbladder mucosa is strongly associated with Helicobacter pylori existed in stomach. Helicobacter pylori is also correlated with gallbladder premalignant lesions including metaplasia and adenomyomatosis. The potential mechanism might be related with higher ROS/RNS production but needs further investigation.
Prognostic factors for bronchoscopic intervention in advanced lung or esophageal cancer patients with malignant airway obstruction

CONTEXT: Bronchoscopic intervention can provide immediate relief from suffocation and an opportunity for additional treatment in patients with malignant airway obstruction. However, few studies have specifically identified prognostic factors affecting the survival of advanced lung or esophageal cancer patients receiving bronchoscopic intervention. AIMS: We aimed to investigate prognostic factors influencing survival in these patients. STUDY DESIGN: We conducted retrospective study. METHODS: The clinical parameters were retrospectively reviewed in 51 patients (lung cancer: n = 35; esophageal cancer: n = 16) who underwent palliative bronchoscopic interventions due to malignant airway. RESULTS: Bronchoscopic interventions, such as mechanical removal (n = 26), stenting (n = 31), laser cauterization (n = 19), and ballooning (n = 16), were performed on intraluminal (n = 21, 41%), extrinsic (n = 8, 16%), and combined lesions (n = 22, 43%). Tracheal invasion was found in 24 patients (47%). Successful palliation was achieved in 49 patients (96%). After the intervention, additional anti-cancer treatment was followed in 24 patients (47%). The median survival time and overall survival rate were 3.4 months and 4%. Survival was increased with selected conditions, including a treatment-naïve status (hazard ratio [HR], 0.359; confidence interval [CI], 0.158-0.815; P = 0.01), an intact proximal airway (HR, 0.265; CI, 0.095-0.738; P = 0.01), and post-procedural additional treatment (HR, 0.330; CI, 0.166-0.657; P < 0.01). CONCLUSIONS: Brochoscopic intervention could provide immediate relief and survival improvement in advanced lung or esophageal cancer patients with selected conditions such as a treatment-naïve status, an intact proximal airway, and available post-procedural additional treatment.
Slurpie: a cooperative bulk data transfer protocol

We present Slurpie: a peer-to-peer protocol for bulk data transfer. Slurpie is specifically designed to reduce client download times for large, popular files, and to reduce load on servers that serve these files. Slurpie employs a novel adaptive downloading strategy to increase client performance, and employs a randomized backoff strategy to precisely control load on the server. We describe a full implementation of the Slurpie protocol, and present results from both controlled local-area and wide-area testbeds. Our results show that Slurpie clients improve performance as the size of the network increases, and the server is completely insulated from large flash crowds entering the Slurpie network.
Narrative Research in Action Combining thematic and narrative analysis of qualitative interviews to understand children ’ s spatialities in Andhra Pradesh , India

One of the foremost questions for any researcher setting out on a qualitative study is which form of analysis to use. There are a diverse range of qualitative analytical methods, each offering different forms of insight. In this paper, we discuss our experience of combining two distinct but complementary analytic methods – thematic and narrative analysis. We provide a worked example that combines the two approaches to analyse secondary data from the Young Lives study (see www.younglives.org.uk), in a project carried out as part of the ESRC National Centre for Research Methods Node, NOVELLA (Narratives of Varied Everyday Lives and Linked Approaches, see www.novella.ac.uk). We reflect on the challenges and benefits that result from our combined approach, aiming to illuminate the ways in which the integration of narrative and thematic analysis can support and enrich understanding of a complex dataset. NOVELLA working paper
Marketing Alliances, Firm Networks, and Firm Value Creation

Prior research has found that the announcement of marketing alliances tends to produce no effect on firm value creation in a high-tech context. This article reexamines this issue and investigates whether the characteristics of a firm's network of alliances affect the firm value created from the announcement of a new marketing alliance. The authors investigate whether network centrality, network density, network efficiency, network reputation, and marketing alliance capability influence firm value creation. They examine this question using an event study of 230 announcements for marketing alliances in the software industry. The results indicate that, in general, marketing alliance announcements create value (i.e., abnormal stock returns) for the firm in the announcement period event window. Furthermore, network efficiency and network density have the strongest positive impact when they are moderate; network reputation and network centrality have no effect. These results point to the greater role of relational network characteristics than size-/status-based benefits. Finally, marketing alliance capability, which reflects a firm's ability to manage a network of previous marketing alliances, has a positive impact on value creation.
Dermal analogue tumours of major salivary glands

Monomorphic adenomas of the major salivary glands manifest a histologic spectrum whose diversity rivals that of pleomorphic adenomas. In nearly all forms of monomorphic adenomas there are histologic features which recall stages in the embryonic development of salivary glands and/or adenexae of skin. A close histogenetic relationship between certain monomorphic adenomas and certain adenexal tumours of skin is suggested by the findings of this report. Within the diversity of expression found in monomorphic adenomas are subsets of tumours which are analogous and nearly homologous with dermal appendage tumours, especially the dermal eccrine cylindroma. The analogous relationship is carried further by a proposed diathesis in which patients exhibit histologically similar tumours in their salivary glands and skin.
Expression of matrix metalloproteinase-2 and -9 and membrane-type 1 matrix metalloproteinase in melanocytic tumors of dogs and canine melanoma cell lines.

OBJECTIVE To evaluate expression of matrix metalloproteinase (MMP)-2 and -9 and membrane-type 1 MMP (MT1-MMP) in melanocytomas and malignant melanomas of dogs, analyze in vitro production of MMPs by canine melanoma cell lines and primary dermal fibroblasts, and investigate mutual communication between tumor cells and fibroblasts and the influence of collagen on MMP regulation. SAMPLE 35 biopsy specimens from melanocytic tumors and primary dermal fibroblasts of dogs and 3 canine melanoma cell lines (CML-1, CML-10c2, and CML-6M). PROCEDURES MMP-2, MMP-9, and MT1-MMP were detected in tumor samples by use of immunohistochemical analysis. In vitro production was analyzed via reverse transcriptase-PCR assay, immunocytochemical analysis, zymography, and immunoblotting. RESULTS MMP-9 was overexpressed in malignant melanomas, compared with expression in melanocytomas, whereas no significant differences in MMP-2 and MT1-MMP immunostaining were detected. Stromal cells also often had positive staining results. In vitro, all 3 melanoma cell lines and dermal fibroblasts had evidence of MMP-2 and MT1-MMP, but only melanoma cells had evidence of MMP-9. Coculture of CML-1 or CML-10c2 cells and dermal fibroblasts induced an increase in expression of the active form of MMP-2. Culture of melanoma cells on type I collagen increased the activation state of MT1-MMP. CONCLUSIONS AND CLINICAL RELEVANCE MMP-9 expression was increased in malignant melanomas of dogs. Stromal cells were a source for MMPs. Stromal cells, in combination with matrix components such as type I collagen, can interact with tumor cells to regulate MMP production. Information about MMP production and regulation could help in the development of new treatments.
SPREAD: enhancing data confidentiality in mobile ad hoc networks

Security is a critical issue in a mobile ad hoc network (MANET). We propose and investigate a novel scheme, security protocol for reliable data delivery (SPREAD), to enhance the data confidentiality service in a mobile ad hoc network. The proposed SPREAD scheme aims to provide further protection to secret messages from being compromised (or eavesdropped) when they are delivered across the insecure network. The basic idea is to transform a secret message into multiple shares by secret sharing schemes and then deliver the shares via multiple independent paths to the destination so that even if a small number of nodes that are used to relay the message shares are compromised, the secret message as a whole is not compromised. We present the overall system architecture and investigate the major design issues. We first describe how to obtain message shares using the secret sharing schemes. Then we study the appropriate choice of the secret sharing schemes and the optimal allocation of the message shares onto each path in order to maximize the security. The results show that the SPREAD is more secure and also provides a certain degree of reliability without sacrificing the security. Thirdly, the multipath routing techniques are discussed and the path set optimization algorithm is developed to find the multiple paths with the desired property, i.e., the overall path set providing maximum security. Finally, we present the simulation results to justify the feasibility and evaluate the effectiveness of SPREAD.
Proposed Electronic Calculator report for National Physical Laboratory Teddington Universal Turing Machine

Biologists agree that empathic models are an interesting new topic in the field of electrical engineering, and hackers worldwide concur. In fact, few systems engineers would disagree with the improvement of 802.11b, which embodies the structured principles of hardware and architecture. We use client-server models to confirm that the acclaimed collaborative algorithm for the visualization of the World