Miracle-dz/UniFAR-FTUs huggingface dataset:
A combined laboratory and field evaluation of the Cholestech LDX and CardioChek PA point-of-care testing lipid and glucose analysers

Background Combined lipid and glucose point-of-care testing (POCT) devices could facilitate widespread population screening for cardiovascular disease (CVD) and diabetes as part of the NHS Vascular Risk Assessment and Management Program (NHS Health Checks). An evaluation of the Cholestech LDX and CardioChek PA POCT analysers was performed in collaboration with the Wolverhampton City Primary Care Trust (PCT). Methods Intra-/inter-batch imprecision, between-analyser variation and the effect of haematocrit and ascorbic acid assay interference were investigated. Accuracy of the POCT capillary whole blood total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C) and glucose measurements was estimated by comparison with those from the laboratory analysis of paired venous samples. POCT usability and clinical governance were also assessed. Results The LDX exhibited lower intra- and inter-batch imprecision and external quality assessment (EQA) scheme between-analyser variation for the measurement of TC, HDL-C and glucose when compared to the CardioChek. Ascorbic acid negatively interfered in all three assays on both POCT analysers and results reported by the CardioChek were influenced by the specimen haematocrit. The LDX displayed closer agreement with the laboratory methods for the measurement of TC and HDL-C but both the LDX and the CardioChek displayed positive bias for the measurement of glucose. Conclusions POCT has clear advantages for delivering NHS Health Checks over the laboratory-based approach although device performance does differ. Users should also be aware of the potential clinical governance and interference issues associated with these devices.
Effect of power-training intensity on the contribution of force and velocity to peak power in older adults.

OBJECTIVE To determine the effect of training intensity on the contributions of force and velocity to improvements in peak power (PP) after explosive resistance training in older adults. METHODS 112 healthy older adults (69 +/- 6 yr) were randomized to explosive resistance training at 20% (G20), 50% (G50), or 80% (G80) maximal strength (1-repetition maximum) for 8-12 wk (twice weekly, 5 exercises, 3 sets of 8 explosive concentric/slow eccentric repetitions) using pneumatic resistance machines or a nontraining control group (CON). RESULTS Force at peak power (FPP) increased significantly and similarly among training groups compared with CON. Velocity at peak power (VPP) did not improve significantly and remained similar between all groups. Force contributed significantly more to PP production in G80 and G50 than in CON. The change in PP was independently predicted by changes in fat-free mass in G80 and by changes in both FPP and VPP in G50 and G20. CONCLUSION Explosive resistance training in older adults results in the ability to produce higher PP outputs with heavier loads without loss of movement velocity. Moderate- to high-intensity training induced a greater relative contribution of force to PP production in this cohort.
The Role of Social Work Norms in Job Searching and Subjective Well-Being

Social norms are usually neglected in economics, because they are to a large extent enforced through nonmarket interactions and difficult to isolate empirically. In this paper, we offer a direct measure of the social norm to work and we show that this norm has important economic effects. The stronger the norm, the more quickly unemployed people find a new job. This behavior can be explained by utility differences, probably due to social pressure. Unemployed people are significantly less happy than employed people and their reduction in life satisfac-tion is the larger, the stronger the norm is. (JEL: I31, J64) Copyright (c) 2004 The European Economic Association.
Comparison of gender and group differences in self-report and physical performance measures in total hip and knee arthroplasty candidates.

Functional measures (fast self-paced walk test, stair climb, and timed up and go) and a self-report measure of function (Lower Extremity Activity Profile) were assessed in 1,805 total hip (761) and knee (1044) arthroplasty candidates (1,063 women, 742 men) preoperatively. Women represented 59% of the study subjects and showed greater disability than men (P <or= .001) in the physical performance and self-report measures. Although the hip arthroplasty group perceived greater functional disability and less satisfaction, the impact of osteoarthritis on the hip and knee was similar in terms of walking and stair performance. Overall, there was low-to-moderate correlation between the self-report and physical performance measures (r = .21- .50).
Global -Stability Analysis for Impulsive Stochastic Neural Networks with Unbounded Mixed Delays

We investigate the global -stability in the mean square of impulsive stochastic neural networks with unbounded time-varying delays and continuous distributed delays. By choosing an appropriate Lyapunov-Krasovskii functional, a novel robust stability condition, in the form of linear matrix inequalities, is derived. These sufficient conditions can be tested by MATLAB LMI software packages. The results extend and improve the earlier publication. Two numerical examples are provided to illustrate the effectiveness of the obtained theoretical results.
Autos and Progress: The Brazilian Search for Modernity

Autos and Progress studies the automobile as both a tool and a cultural symbol of Brazil's status as a modern "developed" nation. As such it addresses debates on state-making, the role of multi-national corporations in the region, middle-class consumerism, working-class politics, and sports and leisure in the crafting of national identity, among others. Such a study is key for understanding the twentieth century because auto-based transportation became the central facet of Brazilian attempts to gain control over its massive national space. The most obvious expressions of this include the building of Brasilia to be the new, interior national capital, the extensive road building throughout the Amazon in the 1970s, the nation's development of one of the world's leading alternative fuel industries, Brazilian dominance in world Formula One racing, and the fact that the current president, Luiz Inacio Lula da Silva, is a former auto worker and trade union leader. This focus on Brazilians' fascination with automobiles and their reliance on auto production and consumption as keys to their economic and social transformation, explains how Brazil -- which enshrined its belief in science and technology in its national slogan of Order and Progress -- has differentiated itself from other Latin American nations. This embrace of automobility allowed the Brazilian elite to use industrialism and the increased mobility of an auto-based society to attempt to remake the nation's poor into a more homogeneous population. Autos and Progress engages key issues in the Brazil around the meaning and role of race in society and also addresses several classic debates in Brazilian studies about the nature of Brazil's great size and diversity and how they shaped state-making. Autos and Progress unifies Brazilian economics, politics, and culture in the twentieth century. It provides a unique historical context for understanding Brazilian modernism in politics and culture. Moreover, by analyzing the origins of auto-oriented industrialism and consumerism, the book is an economic, cultural and social history of Brazilian attempts to remake the nation into a middle-class democracy. This aspect of the study presents a new interpretation for the rise of Brazil's New Unionism, which was born in Brazil's auto, truck, and bus factories. It also provides important context for understanding the place of the Partido dos Trabalhadores (Workers' Party) in national politics and culture, and the rise of President Luiz Inacio Lula da Silva, a former auto worker.
Grand designs! analysing the conceptual tensions associated with new physical education and health and well-being curriculum

The positioning of physical education in the school curriculum continues to reflect external discourses circulating in political and social milieu. As increasing austerity measures influence and restrict educational priorities, we consider that there is an urgent need for physical educationalists to articulate a rationale for an educational contribution which is worthy of investment and which avoids the pitfalls of conceptual ambiguity and/or reliance on narrowly drawn health evidence. We, therefore, write as teacher educators, working within a critical framework, who are concerned by the disconnection between competing visions of physical education, when examined from contemporary sociological and philosophical perspectives. With reference to the policy opportunities available in Scotland, we identify how cultivating salutogenic approaches, where a broad, but nevertheless coherent perspective on health and well-being is advanced could offer enhanced prospects for the centrality of physical education in education and schooling. However, apart from the contribution of Quennerstedt, quite how such approaches can be modelled in curriculum has received little critical attention. We see the potential in applying Tiberius's philosophical and social psychological ideas on developing reflective wisdom and of nurturing in education productive experiences which can help pupils deepen their understanding of the health and well-being decisions they make and of the lives they choose to live. After reviewing the contextual influences on policy, we have begun to consider in embryonic terms the methodological possibilities for teachers as insightful and active curriculum decision makers in years to come. We conclude by summarising the benefits of re-conceptualising experiences in physical education in order to help pupils' make informed decisions which are based on enhanced self-awareness and a perspective on the world that views physical education as an essentially optimistic and good endeavour which is worthy of sustained commitment.
Visual navigation of a mobile robot with laser-based collision avoidance

In this paper, we propose and validate a framework for visual navigation with collision avoidance for a wheeled mobile robot. Visual navigation consists of following a path, represented as an ordered set of key images, which have been acquired by an on-board camera in a teaching phase. While following such a path, the robot is able to avoid obstacles which were not present during teaching, and which are sensed by an on-board range scanner. Our control scheme guarantees that obstacle avoidance and navigation are achieved simultaneously. In fact, in the presence of obstacles, the camera pan angle is actuated to maintain scene visibility while the robot circumnavigates the obstacle. The risk of collision and the eventual avoiding behaviour are determined using a tentacle-based approach. The framework can also deal with unavoidable obstacles, which make the robot decelerate and eventually stop. Simulated and real experiments show that with our method, the vehicle can navigate along a visual path while avoiding collisions.
A gain-of-function mutation in ftsA bypasses the requirement for the essential cell division gene zipA in Escherichia coli

ZipA and FtsA are recruited independently to the FtsZ cytokinetic ring (Z ring) and are essential for cell division of Escherichia coli. The molecular role of FtsA in cell division is unknown; however, ZipA is thought to stabilize the Z ring, anchor it to the membrane, and recruit downstream cell division proteins. Here we demonstrate that the requirement for ZipA can be bypassed completely by a single alteration in a conserved residue of FtsA (FtsA*). Cells with ftsA* in single copy in place of WT ftsA or with ftsA* alone on a multicopy plasmid divide mostly normally, whether they are zipA+ or zipA−. Experiments with ftsQAZ and ftsQA*Z on multicopy plasmids indicate that ftsQAZ/zipA+ and ftsQA*Z/zipA− cells divide fairly normally, whereas ftsQAZ/zipA− cells divide poorly and ftsQA*Z/zipA+ cells display a phenotype that suggests their septa are unusually stable. In support of the idea that ftsA* stabilizes Z rings, single-copy ftsA* confers resistance to excess MinC, which destabilizes Z rings. The inhibitory effect of excess ZipA on division is also suppressed by ftsA*. These results suggest that the molecular mechanism of the FtsA* bypass is to stabilize FtsZ assembly via a parallel pathway and that FtsA* can replace the multiple functions of ZipA. This is an example of a complete functional replacement of an essential prokaryotic cell division protein by another and may explain why most bacteria can divide without an obvious ZipA homolog.
The Ghost in the Browser: Analysis of Web-based Malware

As more users are connected to the Internet and conduct their daily activities electronically, computer users have become the target of an underground economy that infects hosts with malware or adware for financial gain. Unfortunately, even a single visit to an infected web site enables the attacker to detect vulnerabilities in the user's applications and force the download a multitude of malware binaries. Frequently, this malware allows the adversary to gain full control of the compromised systems leading to the ex-filtration of sensitive information or installation of utilities that facilitate remote control of the host. We believe that such behavior is similar to our traditional understanding of botnets. However, the main difference is that web-based malware infections are pull-based and that the resulting command feedback loop is looser. To characterize the nature of this rising thread, we identify the four prevalent mechanisms used to inject malicious content on popular web sites: web server security, user contributed content, advertising and third-party widgets. For each of these areas, we present examples of abuse found on the Internet. Our aim is to present the state of malware on the Web and emphasize the importance of this rising threat.
An analysis of 3105 Medico Legal Cases at Tertiary Care Hospital, Rawalpindi

Background and Objectives: Medico legal cases are essential component of medical practice and comprise most important constituent of emergencies. The reporting of such cases is imperative to recognize theirsocioeconomic burden on any country. The present study was conducted to scrutinize different categories of medico legal cases and characteristics of the victims at casualty department oftertiary care hospital Rawalpindi. The objective of the study was to find out the frequency ofvarious categories of medico legal cases and major characteristics ofvictims at tertiary care hospital, Rawalpindi. Methods: This was a cross-sectional study on 3105 registered cases in medico legal record of the casualty department of Benazir Bhutto hospital, Rawalpindi from January 2015 to December 2015. The hospital is located on the main road in densely populated central area of the city. The data wascollected on age, sex, month-wise distribution of various medico legal cases, weapon inflicting the injury, blunt trauma or physical assault, firearm injuries and road traffic accidents. The data thus obtained was analyzed using SPSS; observations were presented in tables and graphs. Results: Out of all 3105 registered medico legal cases, reported cases caused by Road Traffic Accident 1230 (40%) followed by blunt injury or physical assault 966 (32%) cases, 19% by sharp weapons, 5% by poisoning, and 4% by firearm injuries. In our study out of 3105 cases, almost three quarter of victims (73%) were below 30 years of age, with a decreasing frequency beyond this age, males were predominantly inflicted 2516(81%) as compared to females 589 (19%). The reported road traffic accidents cases from urban areas were high (74%) as compared to those from rural locality (37%). In cases of blunt trauma, sharp weapon injuries and firearm injuries, there was a huge preponderance of victims from rural areas (65%), (62%) and 61% respectively, with urban cases constituting less. Conclusion: Road traffic injuries are one of the foremost causes of medico legal cases followed by blunt trauma and sharp weapon injuries. The emerging medico legal cases are neglected epidemic in most of the developing countries comprising a considerable public health problem.
Kyoto University Participation to WAT 2017

We describe here our approaches and results on the WAT 2017 shared translation tasks. Following our good results with Neural Machine Translation in the previous shared task, we continue this approach this year, with incremental improvements in models and training methods. We focused on the ASPEC dataset and could improve the state-of-the-art results for Chinese-to-Japanese and Japanese-to-Chinese translations.
Psychopathic Traits and Moral Disengagement Interact to Predict Bullying and Cyberbullying Among Adolescents

The aim of this study was to test a model in which psychopathic traits (callous-unemotional, grandiose-manipulative, and impulsive-irresponsible) and moral disengagement individually and interactively predict two types of bullying (traditional and cyberbullying) in a community sample of adolescents. A total of 765 adolescents (464 girls and 301 boys) completed measures of moral disengagement and psychopathic traits at Time 1, and measures of bullying and cyberbullying at Time 1 and 1 year later, at Time 2. The results showed that callous-unemotional traits predicted both traditional bullying and cyberbullying, grandiose-manipulative and impulsive-irresponsible traits only predicted traditional bullying, and moral disengagement only predicted cyberbullying. Callous-Unemotional Traits × Moral Disengagement and Grandiose-Manipulative × Moral Disengagement were significantly correlated with the residual change in cyberbullying. Callous-unemotional traits were positively related to cyberbullying at high levels of moral disengagement but not when moral disengagement was low. In contrast, grandiose-manipulative traits were positively related to cyberbullying at low levels of moral disengagement but not when moral disengagement was high. These findings have implications for both prevention and intervention. Integrative approaches that promote moral growth are needed, including a deeper understanding of why bullying is morally wrong and ways to stimulate personality traits that counteract psychopathic traits.
Ferrite-Filled Antisymmetrically Biased Rectangular Waveguide Isolator Using Magnetostatic Surface Wave Modes

The complex dispersion diagram of an antisymmetrically biased ferrite-filled rectangular waveguide (RWG) is investigated, revealing that the waveguide supports a band-limited unidirectional magnetostatic surface wave mode. This mode is subsequently used to design a novel RWG isolator. A parametric analysis including loss is performed to characterize the isolation band. A prototype waveguide isolator has been fabricated using a small metallized ferrite substrate measuring 30-mm long, 6-mm wide, and 0.8-mm high. Measurements in the 10-20-GHz range confirm the theory and mark the first time that a ferrite isolator has been built using a completely filled RWG. The fabricated 6-mm-long waveguide isolator provides a peak isolation figure-of-merit (IFM) of 42.5 dB at 15.4 GHz. An IFM of over 16.2 dB is sustained from 15.2 to 18.3 GHz (18.5% bandwidth). The simplicity of this compact isolator makes it amenable to package-scale integration, such as in ferrite low-temperature co-fired ceramic, where it could be readily embedded within a multichip package.
Complex Contagions and the Weakness of Long Ties1

The strength of weak ties is that they tend to be long—they connect socially distant locations, allowing information to diffuse rapidly. The authors test whether this “strength of weak ties” generalizes from simple to complex contagions. Complex contagions require social affirmation from multiple sources. Examples include the spread of high‐risk social movements, avant garde fashions, and unproven technologies. Results show that as adoption thresholds increase, long ties can impede diffusion. Complex contagions depend primarily on the width of the bridges across a network, not just their length. Wide bridges are a characteristic feature of many spatial networks, which may account in part for the widely observed tendency for social movements to diffuse spatially.
Arsenate substitution in hydroxylapatite: Structural characterization of the Ca5(PxAs1–xO4)3OH solid solution

Abstract Arsenate (As5+) substitution in the hydroxylapatite structure was examined using a combination of crystallographic and spectroscopic techniques. Samples of hydroxylapatite, the As5+-substituted analog (synthetic johnbaumite), and five intermediate compositions were synthesized from solution. Synchrotron X-ray diffraction data show that all samples are single-phase, confirming complete substitution. No evidence is found for lowering of symmetry below P63/m. Rietveld structure refinements show progressive expansion of the unit cell with increasing As substitution, which can be accounted for primarily by an average expansion of the tetrahedral site. Sizes of Ca polyhedra show little variation as a result of As substitution. NMR results show no evidence for local clustering of PO4 tetrahedra. EXAFS confirms that the size of As-centered tetrahedra remains constant across the solid-solution series.
Radar interferometry offers new insights into threats to the Angkor site

New insights into threats to the Angkor site and implications for the sustainable conservation of World Heritage sites elsewhere. The conservation of World Heritage is critical to the cultural and social sustainability of regions and nations. Risk monitoring and preventive diagnosis of threats to heritage sites in any given ecosystem are a complex and challenging task. Taking advantage of the performance of Earth Observation technologies, we measured the impacts of hitherto imperceptible and poorly understood factors of groundwater and temperature variations on the monuments in the Angkor World Heritage site (400 km2). We developed a two-scale synthetic aperture radar interferometry (InSAR) approach. We describe spatial-temporal displacements (at millimeter-level accuracy), as measured by high-resolution TerraSAR/TanDEM-X satellite images, to provide a new solution to resolve the current controversy surrounding the potential structural collapse of monuments in Angkor. Multidisciplinary analysis in conjunction with a deterioration kinetics model offers new insights into the causes that trigger the potential decline of Angkor monuments. Our results show that pumping groundwater for residential and touristic establishments did not threaten the sustainability of monuments during 2011 to 2013; however, seasonal variations of the groundwater table and the thermodynamics of stone materials are factors that could trigger and/or aggravate the deterioration of monuments. These factors amplify known impacts of chemical weathering and biological alteration of temple materials. The InSAR solution reported in this study could have implications for monitoring and sustainable conservation of monuments in World Heritage sites elsewhere.
Application of nitric oxide measurements in clinical conditions beyond asthma

Fractional exhaled nitric oxide (FeNO) is a convenient, non-invasive method for the assessment of active, mainly Th2-driven, airway inflammation, which is sensitive to treatment with standard anti-inflammatory therapy. Consequently, FeNO serves as a valued tool to aid diagnosis and monitoring in several asthma phenotypes. More recently, FeNO has been evaluated in several other respiratory, infectious, and/or immunological conditions. In this short review, we provide an overview of several clinical studies and discuss the status of potential applications of NO measurements in clinical conditions beyond asthma.