Miracle-dz/UniFAR-FTUs huggingface dataset:
Motion correction for infant functional near-infrared spectroscopy with an application to live interaction data

Abstract. Correcting for motion is an important consideration in infant functional near-infrared spectroscopy studies. We tested the performance of conventional motion correction methods and compared probe motion and data quality metrics for data collected at different infant ages (5, 7, and 12 months) and during different methods of stimulus presentation (video versus live). While 5-month-olds had slower maximum head speed than 7- or 12-month-olds, data quality metrics and hemodynamic response recovery errors were similar across ages. Data quality was also similar between video and live stimulus presentation. Motion correction algorithms, such as wavelet filtering and targeted principal component analysis, performed well for infant data using infant-specific parameters, and parameters may be used without fine-tuning for infant age or method of stimulus presentation. We recommend using wavelet filtering with iqr=0.5; however, a range of parameters seemed acceptable. We do not recommend using trial rejection alone, because it did not improve hemodynamic response recovery as compared to no correction at all. Data quality metrics calculated from uncorrected data were associated with hemodynamic response recovery error, indicating that full simulation studies may not be necessary to assess motion correction performance.
Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer.

BACKGROUND Laboratory studies have shown that n-3 fatty acids inhibit and n-6 fatty acids stimulate prostate tumor growth, but whether the dietary intake of these fatty acids affects prostate cancer risk in humans remains unclear. OBJECTIVE We prospectively evaluated the association between intakes of alpha-linolenic (ALA; 18:3n-3), eicosapentaenoic (EPA; 20:5n-3), docosahexaenoic (DHA; 22:6n-3), linoleic (LA; 18:2n-6), and arachidonic (AA; 20:4n-6) acids and prostate cancer risk. DESIGN A cohort of 47 866 US men aged 40-75 y with no cancer history in 1986 was followed for 14 y. RESULTS During follow-up, 2965 new cases of total prostate cancer were ascertained, 448 of which were advanced prostate cancer. ALA intake was unrelated to the risk of total prostate cancer. In contrast, the multivariate relative risks (RRs) of advanced prostate cancer from comparisons of extreme quintiles of ALA from nonanimal sources and ALA from meat and dairy sources were 2.02 (95% CI: 1.35, 3.03) and 1.53 (0.88, 2.66), respectively. EPA and DHA intakes were related to lower prostate cancer risk. The multivariate RRs of total and advanced prostate cancer from comparisons of extreme quintiles of the combination of EPA and DHA were 0.89 (0.77, 1.04) and 0.74 (0.49, 1.08), respectively. LA and AA intakes were unrelated to the risk of prostate cancer. The multivariate RR of advanced prostate cancer from a comparison of extreme quintiles of the ratio of LA to ALA was 0.62 (0.45, 0.86). CONCLUSIONS Increased dietary intakes of ALA may increase the risk of advanced prostate cancer. In contrast, EPA and DHA intakes may reduce the risk of total and advanced prostate cancer.
Cover crop root contributions to soil carbon in a no-till corn bioenergy cropping system

Crop residues are potential biofuel feedstocks, but residue removal may reduce soil carbon (C). The inclusion of a cover crop in a corn bioenergy system could provide additional biomass, mitigating the negative effects of residue removal by adding to stable soil C pools. In a no-till continuous corn bioenergy system in the northern US Corn Belt, we used CO2 pulse labeling to trace plant C from a winter rye (Secale cereale) cover crop into different soil C pools for 2 years following rye cover crop termination. Corn stover left as residue (30% of total stover) contributed 66, corn roots 57, rye shoots 61, rye roots 50, and rye rhizodeposits 25 g C m 2 to soil. Five months following cover crop termination, belowground cover crop inputs were three times more likely to remain in soil C pools than were aboveground inputs, and much of the root-derived C was in mineral-associated soil fractions. After 2 years, both aboveand belowground inputs had declined substantially, indicating that the majority of both root and shoot inputs are eventually mineralized. Our results underscore the importance of cover crop roots vs. shoots and the importance of cover crop rhizodeposition (33% of total belowground cover crop C inputs) as a source of soil C. However, the eventual loss of most cover crop C from these soils indicates that cover crops will likely need to be included every year in rotations to accumulate soil C.
ar X iv : 1 10 3 . 37 03 v 1 [ as tr o-ph . C O ] 1 8 M ar 2 01 1 On the Clustering of Sub-millimeter Galaxies

We measure the angular two-point correlation function of sub-millimeter galaxies (SMGs) from 1.1-millimeter imaging of the COSMOS field with the AzTEC camera and ASTE 10-meter telescope. These data yields one of the largest contiguous samples of SMGs to date, covering an area of 0.72 degrees down to a 1.26 mJy/beam (1-σ) limit, including 189 (328) sources with S/N≥ 3.5 (3). We can only set upper limits to the correlation length r0, modeling the correlation function as a power-law with pre-assigned slope. Assuming existing redshift distributions, we derive 68.3% confidence level upper limits of r0 . 68 hMpc at 3.7 mJy, and r0 . 11-12 h Mpc at 4.2 mJy. Although consistent with most previous estimates, these upper limits imply that the real r0 is likely smaller. This casts doubts on the robustness of claims that SMGs are characterized by significantly stronger spatial clustering, (and thus larger mass), than differently selected galaxies at high-redshift. Using Monte Carlo simulations we Astronomy Department, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA, ccwillia@astro.umass. edu Argelander-Institut für Astronomie der Universität Bonn, Auf dem Hügel 71, D-53121 Bonn, Germany Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104, USA Center for Astrophysics and Space Astronomy, University of Colorado, Boulder, CO 80309, USA Instituto Nacional de Astrofisica, Optica y Electronica (INAOE), Aptdo. Postal 51 y 216, 72000 Puebla, Pue. , Mexico Nobeyama Radio Observatory, Minamimaki, Minamisaku, Nagano 384-1805, Japan Yale Center for Astronomy and Astrophysics, Department of Physics, Yale University, New Haven, CT 06520, USA Institute of Astronomy, the University of Tokyo, 2-21-1 Osawa, Mitaka, Tokyo 181-0015, Japan Department of Physics, Illinois Wesleyan University, Bloomington, IL 61701, USA
Ducks and passerines nesting in northern mixed‐grass prairie treated with fire

Prescribed fire is an important, ecology-driven tool for restoration of grassland systems. However, prescribed fire remains controversial for some grassland managers because of reported reductions in bird use of recently burned grasslands. Few studies have evaluated effects of fire on grassland bird populations in the northern mixed-grass prairie region. Fewer studies yet have examined the influence of fire on nest density or survival. In our review, we found no studies that simultaneously examined effects of fire on duck and passerine nesting. During 1998–2003, we examined effects of prescribed fire on the density of upland-nesting ducks and passerines nesting in north-central North Dakota, USA. Apparent nest densities of gadwall (Anas strepera), mallard (A. platyrhynchos), and all duck species combined, were influenced by fire history of study units, although the degree of influence was not compelling. Fire history was not related to nest densities of blue-winged teal (A. discors), northern shoveler (A. clypeata), or northern pintail (A. acuta); however, apparent nest densities in relation to the number of postfire growing seasons exhibited a strikingly similar pattern among all duck species. When compared to ducks, fire history strongly influenced apparent nest densities of clay-colored sparrow (Spizella pallida), Savannah sparrow (Passerculus sandwichensis), and bobolink (Dolichonyx oryzivorus). For most species examined, apparent nest densities were lowest in recently burned units, increased during the second postfire growing season, and stabilized or, in some cases, decreased thereafter. Prescribed fire is critical for restoring the ecology of northern mixed-grass prairies and our findings indicate that reductions in nest densities are limited mostly to the first growing season after fire. Our results support the premise that upland-nesting ducks and several grassland passerine species are adapted to periodic fires occurring at a frequency similar to that of pre-Euro-American settlement of the region. © 2011 The Wildlife Society.
Effects of school milk intervention on cortical bone accretion and indicators relevant to bone metabolism in Chinese girls aged 10-12 y in Beijing.

BACKGROUND We previously reported that increased milk consumption enhances growth and bone mineral accretion in Chinese girls aged 10-12 y. OBJECTIVE Our objective was to evaluate the effects of milk supplementation on cortical bone accretion and to study the physiologic mechanisms underlying the observed changes in bone. DESIGN Chinese girls aged 10 y were randomly assigned into calcium-fortified milk (Ca milk), calcium and vitamin D-fortified milk (CaD milk), and control groups according to their schools in a 24-mo school milk intervention trial. Periosteal and medullary diameters of metacarpal bone were measured at baseline and 24 mo in the Ca milk (n = 177), CaD milk (n = 210), and control (n = 219) groups. Insulin-like growth factor I (IGF-I), parathyroid hormone (PTH), bone alkaline phosphatase (BAP), osteocalcin, and deoxypyridinoline concentrations were measured at baseline and at 12 and 24 mo in the Ca milk (n = 43), CaD milk (n = 44), and control (n = 41) groups. RESULTS After adjustment for pubertal status and clustering by school, 24-mo supplementation led to greater increases in periosteal diameter (1.2%) and cortical thickness (5.7%) and to smaller gains in medullary diameter (6.7%) than did the control (P < 0.05). The CaD milk group had lower serum BAP at 12 mo (19.9%) and lower serum PTH at 12 (46.2%) and 24 (16.4%) mo than did the control group (P < 0.05). The effect of milk supplementation on increasing IGF-I concentrations at 24 mo (16.7-23.3%) was significant in individual analyses but not after adjustment for clustering by school. CONCLUSIONS Milk supplementation showed positive effects on periosteal and endosteal apposition of cortical bone.
Feedback and recycled wind accretion: assembling the z= 0 galaxy mass function

We analyse cosmological hydrodynamic simulations that include theoretically and observationally motivated prescriptions for galactic outflows. If these simulated winds accurately represent winds in the real Universe, then material previously ejected in winds provides the dominant source of gas infall for new star formation at redshifts z < 1. This recycled wind accretion, or wind mode, provides a third physically distinct accretion channel in addition to the 'hot' and 'cold' modes emphasized in recent theoretical studies. The recycling time of wind material (t rec ) is shorter in higher mass systems owing to the interaction between outflows and the increasingly higher gas densities in and around higher mass haloes. This differential recycling plays a central role in shaping the present-day galaxy stellar mass function (GSMF), because declining t rec leads to increasing wind mode galaxy growth in more massive haloes. For the three feedback models explored, the wind mode dominates above a threshold mass that primarily depends on wind velocity; the shape of the GSMF therefore can be directly traced back to the feedback prescription used. If we remove all particles that were ever ejected in a wind, then the predicted GSMFs are much steeper than observed. In this case, galaxy masses are suppressed both by the ejection of gas from galaxies and by the hydrodynamic heating of their surroundings, which reduces subsequent infall. With wind recycling included, the simulation that incorporates our favoured momentum-driven wind scalings reproduces the observed GSMF for stellar masses 10 9 M ⊙ M ≤ 5 × 10 10 M ⊙ . At higher masses, wind recycling leads to excessive galaxy masses and star formation rates relative to observations. In these massive systems, some quenching mechanism must suppress not only the direct accretion from the primordial intergalactic medium but the re-accretion of gas ejected from star-forming galaxies. In short, as has long been anticipated, the form of the GSMF is governed by outflows; the unexpected twist here for our simulated winds is that it is not primarily the ejection of material but how the ejected material is re-accreted that governs the GSMF.
Dietary cholesterol from eggs increases the ratio of total cholesterol to high-density lipoprotein cholesterol in humans: a meta-analysis.

BACKGROUND Several epidemiologic studies found no effect of egg consumption on the risk of coronary heart disease. It is possible that the adverse effect of eggs on LDL-cholesterol is offset by their favorable effect on HDL cholesterol. OBJECTIVE The objective was to review the effect of dietary cholesterol on the ratio of total to HDL cholesterol. DESIGN Studies were identified by MEDLINE and Biological Abstracts searches (from 1974 to June 1999) and by reviewing reference lists. In addition, we included data from a more recently published study. Studies were included if they had a crossover or parallel design with a control group, if the experimental diets differed only in the amount of dietary cholesterol or number of eggs and were fed for > or =14 d, and if HDL-cholesterol concentrations were reported. Of the 222 studies identified, 17 studies involving 556 subjects met these criteria. RESULTS The addition of 100 mg dietary cholesterol/d increased the ratio of total to HDL cholesterol by 0.020 units (95% CI: 0.010, 0.030), total cholesterol concentrations by 0.056 mmol/L (2.2 mg/dL) (95% CI: 0.046, 0.065 mmol/L; 1.8, 2.5 mg/dL), and HDL-cholesterol concentrations by 0.008 mmol/L (0.3 mg/dL) (95% CI: 0.005, 0.010 mmol/L; 0.2, 0.4 mg/dL). CONCLUSIONS Dietary cholesterol raises the ratio of total to HDL cholesterol and, therefore, adversely affects the cholesterol profile. The advice to limit cholesterol intake by reducing consumption of eggs and other cholesterol-rich foods may therefore still be valid.
A rticle Gene Coexpression Networks Reveal Key Drivers of Phenotypic Divergence in Lake

A functional understanding of processes involved in adaptive divergence is one of the awaiting opportunities afforded by high-throughput transcriptomic technologies. Functional analysis of coexpressed genes has succeeded in the biomedical field in identifying key drivers of disease pathways. However, in ecology and evolutionary biology, functional interpretation of transcriptomic data is still limited. Here, we used Weighted Gene Co-Expression Network Analysis (WGCNA) to identify modules of coexpressed genes in muscle and brain tissue of a lake whitefish backcross progeny. Modules were connected to gradients of known adaptive traits involved in the ecological speciation process between benthic and limnetic ecotypes. Key drivers, that is, hub genes of functional modules related to reproduction, growth, and behavior were identified, and module preservation was assessed in natural populations. Using this approach, we identified modules of coexpressed genes involved in phenotypic divergence and their key drivers, and further identified a module part specifically rewired in the backcross progeny. Functional analysis of transcriptomic data can significantly contribute to the understanding of the mechanisms underlying ecological speciation. Our findings point to bone morphogenetic protein and calcium signaling as common pathways involved in coordinated evolution of trophic behavior, trophic morphology (gill rakers), and reproduction. Results also point to pathways implicating hemoglobins and constitutive stress response (HSP70) governing growth in lake whitefish.
Angiostrongylosis in dogs with negative fecal and in‐clinic rapid serological tests: 7 Cases (2013‐2017)

Background Angiostrongylosis is considered as emerging disease in dogs in Belgium. Detection of first‐stage larvae in feces using the Baermann method has an imperfect sensitivity. Objectives Investigation of efficacy of noninvasive blood and fecal diagnostic tests in comparison with PCR on bronchoalveolar lavage (BAL) material in a small series of coughing or dyspnoeic dogs naturally infected with Angiostrongylus vasorum. Animals Seven dogs with angiostrongylosis. Methods Retrospective study. Dogs with cough, exercise intolerance and dyspnea of 2‐ to 8‐week duration. Diagnostic methods used included Baermann analysis, AngioDetect rapid assay, ELISAs for detection of circulating antigen and specific antibodies and qPCR on BAL material. Results Baermann analysis, AngioDetect rapid assay, antigen ELISA, antibody ELISA, and qPCR on BAL material were positive in 3/7, 2/7, 3/6, 6/6, and 7/7 dogs, respectively. ELISA for antibodies or qPCR on BAL material were essential for definitive diagnosis in 3 dogs. Relative sensitivities of AngioDetect rapid assay, Baermann analysis, and ELISA for antigen detection were lower than 50% compared with ELISA for antibodies or qPCR on BAL material. Conclusion and Clinical Importance In this small clinical series, Baermann analysis and AngioDetect rapid assay failed to confirm the diagnosis in some dogs. Therefore, ELISA for antibody detection and qPCR on BAL material should strongly be considered in clinically suspected dogs when antigen detection methods (AngioDetect or ELISA) and Baermann analysis are negative.
Multiple Modes of Action of the Squamocin in the Midgut Cells of Aedes aegypti Larvae

Annonaceous acetogenins are botanical compounds with good potential for use as insecticides. In the vector, Aedes aegypti (L.) (Diptera: Culicidae), squamocin (acetogenin) has been reported to be a larvicide and cytotoxic, but the modes of action of this molecule are still poorly understood. This study evaluated the changes in the cell morphology, and in the expression of genes, for autophagy (Atg1 and Atg8), for membrane ion transporter V-ATPase, and for water channel aquaporin-4 (Aqp4) in the midgut of A. aegypti larvae exposed to squamocin from Annona mucosa Jacq. (Annonaceae). Squamocin showed cytotoxic action with changes in the midgut epithelium and digestive cells of A. aegypti larvae, increase in the expression for autophagy gene Atg1 and Atg8, decrease in the expression of V-ATPase, decrease in the expression of Aqp4 gene in LC20 and inhibition of Apq4 genes in the midgut of this vector in LC50. These multiple modes of action for squamocin are described for the first time in insects, and they are important because different sites of action of squamocin from A. mucosa may reduce the possibility of resistance of A. aegypti to this molecule.
Testing the effects of explicit and implicit bidimensional attitudes on objectively measured speeding behaviour

Bidimensional attitudes have been shown to independently predict behaviour, with the positive dimension of attitude being a stronger predictor of behaviour than the negative dimension (e.g., Elliott, Brewster, et al., 2015, Br. J. Psychol, 106, 656). However, this positivity bias has been demonstrated with explicit attitude measures only and explicit attitude measures tap deliberative processes rather than automatic processes, which are known to be important in the execution of many behaviours. The aim of this study was to test whether implicit bidimensional attitudes can account for variance in speeding behaviour over and above explicit bidimensional attitudes and whether the positivity bias that is typically found with explicit attitudes generalizes to implicit attitudes. A total of 131 drivers completed a questionnaire measuring their explicit bidimensional attitudes towards speeding. They also completed Implicit Association Tests measuring their implicit bidimensional attitudes. Two weeks later, speeding behaviour was measured using a driving simulator. Explicit attitudes accounted for a significant proportion of the variance in subsequent speeding behaviour. Implicit attitudes accounted for a statistically significant increment to explained variance. The positive dimension of both explicit and implicit attitudes predicted speeding behaviour but the negative dimensions did not. Theoretical implications for understanding the potential attitudinal causes of behaviour and practical implications for behaviour‐change interventions are discussed.
Canalisation in the wild: effects of developmental conditions on physiological traits are inversely linked to their association with fitness.

Ecological conditions affect fitness, but mechanisms causing such effects are not well known, while evolved responses to environmental variation may depend on the underlying mechanisms. Consequences of environmental conditions vary strongly between traits, but a framework to interpret such variation is lacking. We propose that variation in trait response may be explained by differential canalisation, with traits with larger fitness effects showing weaker responses to environmental perturbations due to preferential resource allocation to such traits. We tested the canalisation hypothesis using brood size manipulation in wild jackdaw nestlings in which we measured eight physiological traits (mainly oxidative stress markers), and two feather traits. For each trait, we estimated manipulation response and association with fitness (over-winter survival). As predicted, a strong negative correlation emerged between manipulation response and association with fitness (r =-0.76). We discuss the consequences of differential trait canalisation for the study of mechanisms mediating environmental effects on fitness.
Current Approaches of Photothermal Therapy in Treating Cancer Metastasis with Nanotherapeutics

Cancer metastasis accounts for the high mortality of many types of cancer. Owing to the unique advantages of high specificity and minimal invasiveness, photothermal therapy (PTT) has been evidenced with great potential in treating cancer metastasis. In this review, we outline the current approaches of PTT with respect to its application in treating metastatic cancer. PTT can be used alone, guided with multimodal imaging, or combined with the current available therapies for effective treatment of cancer metastasis. Numerous types of photothermal nanotherapeutics (PTN) have been developed with encouraging therapeutic efficacy on metastatic cancer in many preclinical animal experiments. We summarize the design and performance of various PTN in PTT alone and their combinational therapy. We also point out the lacking area and the most promising approaches in this challenging field. In conclusion, PTT or their combinational therapy can provide an essential promising therapeutic modality against cancer metastasis.