Miracle-dz/UniFAR-FTUs huggingface dataset:
The Accuracy of Implant Placement by Experienced Surgeons: Guided vs Freehand Approach in a Simulated Plastic Model.

PURPOSE To investigate the difference in accuracy between freehand and guided single-implant placement in situations with one or more missing teeth as performed by experienced surgeons. MATERIALS AND METHODS A total of 80 implants were placed by 10 experienced clinicians in the anterior site of maxillary models, made of polyamide by selective laser sintering and mounted in a dummy head. Each clinician performed the same four single-implant cases via freehand surgery and then with a three-dimensional fabricated SIMPLANT Guide. Two of the four cases had a single anterior tooth missing and the other two models represented a partially edentulous situation with several missing anterior teeth. For all 80 implants the average vertical, lateral, and angular deviations between the virtually planned and the achieved implant positions were measured based on a cone beam computed tomography (CBCT) scan. RESULTS Regarding the whole sample, angular deviation was 7.63 degrees for the freehand method and 2.19 degrees for guided surgery. The mean difference in angular deviation differed significantly between groups and was more than three times larger for the freehand method. Lateral deviation at the coronal level of the implants was 0.42 mm and 1.27 mm for the guided and freehand methods, respectively, and at the apical level was 0.52 mm and 1.28 mm for the guided and freehand methods, respectively; the deviation at the coronal and apical levels was significantly smaller for guided surgery than for the freehand method (P = .001). Differences in the depth deviation at the apical and coronal levels were smaller (guided vs freehand surgery at the coronal level: 0.54 mm vs 0.78 mm; apical level: 0.54 mm vs 0.73 mm) but also of statistical significance (P = .05). Differences in angular, global, and lateral deviations between the clinical situations (single vs multiple missing teeth) were also significantly smaller for guided surgery, whereas the deviations in depth did not reveal any statistically significant difference between both methods for the single-spaced units. CONCLUSION In cases of one or more missing teeth in the anterior maxilla, guided surgery gives even experienced surgeons significantly higher predictability and accuracy than freehand surgery in transferring the virtual implant position to a model situation.
Workplace Innovation and Technological Change

This paper explores the extent to which that elusive phenomenon called 'workplace innovation' has pervaded workplaces in Europe and whether it could be one of the answers to Europe’s long-term social and economic challenges that stem from an aging workforce and the need for more flexibility to stay competitive. Basic data drawn from European Working Conditions Survey conducted every five years by the Dublin-based European Foundation for the Improvement of Living and Working Conditions are supplemented by a series of case studies to look at the problems encountered in introducing workplace innovation and possible solutions. One set of case studies examines the following organizations: SGI/GI (Slovak Governance Institute (Slovakia), as representative of the world of small- and medium-sized enterprises; Oticon (Denmark) as representative of manufacturing companies; the Open University (UK), as representative of educational organizations; and FPS Social Security (Belgium) representing the public sector. Two final case studies focus on the country-level, one looking at of how a specific innovation can become fully mainstreamed (in the Netherlands and the ‘part-time economy’) and the other (Finland and TEKES) looking at how a government programme can help disseminate workplace innovation. These six case studies, together with the statistical analysis, constitute the main empirical value added of the report.
Caring in the gym

Caring has been discussed as foundational to developing quality physical activity settings that promote social and personal responsibility and are synonymous with effective teaching practice in physical education. However, how physical educators practice caring in the gym is unclear. Therefore, the purpose of this study was to explore how physical education teachers describe their experiences of caring in the classroom. Six middle school teachers, rated as caring by students, were interviewed using a semi-structured interview guide. Inductive content analysis was used to cluster the raw data quotes into thematic categories which were compared and contrasted to insure uniqueness among the emergent themes. Three overarching themes emerged focusing on 1) being in relation including lower order themes of developing relationships, encouraging/developing caring, and creating connections, 2) creating an inclusive and accepting environment including lower order themes of respecting and trusting students, creating a safe and accepting place, treating students fairly, and being inclusive, and 3) empowering students including lower order themes of supporting development, engaging in caring discipline, and promoting ownership. Results support previous work in the caring literature and further inform practitioners how to work toward developing caring within their own physical activity setting.
Spatial and Temporal Clustering of Anti-Glomerular Basement Membrane Disease.

BACKGROUND AND OBJECTIVES An environmental trigger has been proposed as an inciting factor in the development of anti-GBM disease. This multicenter, observational study sought to define the national incidence of anti-GBM disease during an 11-year period (2003-2014) in Ireland, investigate clustering of cases in time and space, and assess the effect of spatial variability in incidence on outcome. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We ascertained cases by screening immunology laboratories for instances of positivity for anti-GBM antibody and the national renal histopathology registry for biopsy-proven cases. The population at risk was defined from national census data. We used a variable-window scan statistic to detect temporal clustering. A Bayesian spatial model was used to calculate standardized incidence ratios (SIRs) for each of the 26 counties. RESULTS Seventy-nine cases were included. National incidence was 1.64 (95% confidence interval [95% CI], 0.82 to 3.35) per million population per year. A temporal cluster (n=10) was identified during a 3-month period; six cases were resident in four rural counties in the southeast. Spatial analysis revealed wide regional variation in SIRs and a cluster (n=7) in the northwest (SIR, 1.71; 95% CI, 1.02 to 3.06). There were 29 deaths and 57 cases of ESRD during a mean follow-up of 2.9 years. Greater distance from diagnosis site to treating center, stratified by median distance traveled, did not significantly affect patient (hazard ratio, 1.80; 95% CI, 0.87 to 3.77) or renal (hazard ratio, 0.76; 95% CI, 0.40 to 1.13) survival. CONCLUSIONS To our knowledge, this is the first study to report national incidence rates of anti-GBM disease and formally investigate patterns of incidence. Clustering of cases in time and space supports the hypothesis of an environmental trigger for disease onset. The substantial variability in regional incidence highlights the need for comprehensive country-wide studies to improve our understanding of the etiology of anti-GBM disease.
MULTIPLE SHOOT FORMATION FROM DIFFERENT EXPLANTS OF CHICK PEA (CICER ARIETINUM L.)

The direct regeneration ability in different explants i.e., shoot and nodal explants of Cicer arietinum was investigated on M.S. basal medium supplemented with different concentrations of Benzyl amino purine (BAP). Rapid and early shoot initiation was observed in lower concentration of BAP. Higher concentrations delayed shoot initiation in both explants. The number of shoots per explant increased with BAP concentration while shoot length decreased with increasing BAP concentration. The overall response of nodal explant was better than shoot apex. The regeneration shoots were further multiplied by sub culturing on fresh medium. The multiple shoots were shifted to full and half strength M.S. medium supplemented with different concentrations of NAA and IBA for induction of roots while the half strength media with 1.0 uM NAA gave excellent response of root induction.
Mean Field Game of Mutual Holding with common noise

We consider the mean field game of cross--holding introduced in \citeauthor*{DjeteTouzi} \cite{DjeteTouzi} in the context where the equity value dynamics are affected by a common noise. In contrast with \cite{DjeteTouzi}, the problem exhibits the standard paradigm of mean--variance trade off. Our crucial observation is to search for equilibrium solutions of our mean field game among those models which satisfy an appropriate notion of no--arbitrage. Under this condition, it follows that the representative agent optimization step is reduced to a standard portfolio optimization problem with random endowment.
Annals of Clinical Microbiology and Antimicrobials Open Access Inhibitory Activity of Indian Spice Plant Cinnamomum Zeylanicum Extracts against Alternaria Solani and Curvularia Lunata, the Pathogenic Dematiaceous Moulds

Background: Dematiaceous moulds are pathogenic microorganisms and act as etiological agents of mycoses with different degrees of severity in humans and animals. These moulds also cause loss of food crops and storage food products. The information regarding antimicrobial efficacy of the plant preparations on these moulds is scanty. The present study reveals phytochemical characterization and the effect of bark and leaf extracts of Indian spice plant, Cinnamomum zeylanicum (Cz), against the growth of two species of dematiaceous moulds, Alternaria solani and Curvularia lunata.
Construct validity and generalizability of the Carver–White behavioural inhibition system/behavioural activation system scales

The factorial structure and invariance of the BIS/BAS scales of Carver and White were assessed across three samples from the USA, UK, and Italy. Previous validation studies of the BIS/BAS scales relied on individual samples drawn from English‐speaking populations only and failed to formally assess generalizability. The current study shows that the four‐factor structure proposed by Carver and White—i.e. one BIS and three BAS facets—achieved satisfactory psychometric properties in all three samples and that measurement invariance was obtained across countries. Latent mean differences due to gender and country were also investigated. Theoretical issues concerning the validity of the BIS/BAS scales are addressed. Copyright © 2001 John Wiley & Sons, Ltd.
Experiences Developing a Collaborative Travel Planning Application with .NET Web Services

Web services have the potential to provide much more seamless, dynamic and open distributed applications than earlier technologies. We describe our experiences developing an integrated, collaborative travel planning application using . NET, C# and web services. This application provides a unified portal for customers and travel agents to plan, revise and book travel itineraries, with interaction with a wide range of travel provider systems (airlines, hotels, rental cars, trains etc). We describe the web services-based architecture of our prototype solution and discuss some of the key issues of using a web service-based approach for this application domain, outlining key areas for future research and development.
Evidence for an error detection mechanism in motor skills.

One of the fundamental predictions of the Adams (1971) closed-loop theory is that S should develop over practice a perceptual trace which forms the basis of an error detection mechanism. If knowledge of results (KR) is withdrawn, S can use the error detection mechanism to guide performance in its place. To test this notion, 10 Ss practiced 170 trials of a discrete ballistic response, attempting to produce a 9.5-in. manual slider movement in exactly 150 msec. , with KR present except on Trials 11-20 and 141-170. There was an increasing correspondence between the actual errors and Ss' estimation of them as practice continued, and ratings of confidence increased, both of which were indicative of a developing error detection mechanism. During KR withdrawal trials, Ss displayed no worsening of performance, and even continued to learn slightly, suggesting that the error detection mechanism acted as a substitute for KR. The results generally supported Adams' theory.
Positive Dialysate Gram Stain Predicts Outcome of Empirical Antibiotic Therapy for Peritoneal Dialysis‐associated Peritonitis

Empirical antibiotic treatment with a first‐generation cephalosporin plus gentamicin for peritoneal dialysis (PD)‐associated peritonitis before culture results are available is still wildly used due to concerns regarding the economic burden and antibiotic‐resistant bacterial infections. The aim of this study is to define the factors that predict the outcome of empirical antibiotic therapy for PD peritonitis. This is a retrospective study of patients with PD peritonitis over the last 10 years. Patients who had been treated empirically with intermittent intraperitoneal first‐generation cephalosporin and gentamicin were enrolled. Eighty‐three patients had 192 episodes of PD peritonitis. In total, 159 peritonitis episodes were treated with intraperitoneal antibiotics combined with first‐generation cephalosporin and gentamicin empirically. Twenty‐five peritonitis episodes had no pathogens identified by dialysate culture. In total, 122 (122/159, 76.7%) PD peritonitis episodes were caused by bacteria, 9 (9/159, 5.7%) were fungal, and 3 (3/159, 1.9%) were Mycobacterium tuberculosis peritonitis. Sixty‐four (64/159, 40.3%) peritonitis episodes were successfully cured by empirical intraperitoneal antibiotic therapy. Empirical antibiotic treatment failed in 95 episodes (95/159, 59.7%). The positive rates of dialysate Gram stain in the empirical treatment success and failure groups were 15.6% and 40.0%, respectively (P = 0.001). The odds ratio of empirical treatment failure with a positive bacteria Gram stain was 3.60 (95% CI: 1.65–7.82). The dialysate Gram staining result was a significant predictor of empirical antibiotics treatment outcome for PD‐associated peritonitis. Therefore, using an empirical antibiotic regimen for patients with an initial positive bacterial Gram stain of the dialysate should be introduced cautiously.
Random vortex dynamics and Monte-Carlo simulations for wall-bounded viscous flows

Functional integral representations for solutions of the motion equations for wall-bounded incompressible viscous flows, expressed (implicitly) in terms of distributions of solutions to stochastic differential equations of McKean-Vlasov type, are established by using a perturbation technique. These representations are used to obtain exact random vortex dynamics for wall-bounded viscous flows. Numerical schemes therefore are proposed and the convergence of the numerical schemes for random vortex dynamics with an additional force term is established. Several numerical experiments are carried out for demonstrating the motion of a viscous flow within a thin layer next to the fluid boundary.
Ability of stress, sense of control, and self-theories to predict Swedish high school students' final grades

The aim of this study was to investigate self-theories (theories of intelligence, confidence in one's intelligence, internal attribution of failure, academic self-efficacy), specific control, and experiencing of stress by means of a questionnaire for 915 Swedish high school students. Factor analysis yielded 6 stress domains (Workload, Psychosocial Problems, Uncertainty, Problems in Close Relationships, Demands to be Met, Problems of the Physical Environment). The balance between control and stress was measured by the Control-Stress Index. Most of the adolescents' stress appeared to be connected with their schoolwork. Female students, especially in academic programs, experienced greater stress and greater deficit of control than male students. Sequential regression analyses showed that final grades could be predicted to 28% from demographic variables, self-theories, and stress. The contribution of stress was 4%.
E-xams: Harnessing the Power of ICTs to Enhance Authenticity

Within an authentic assessment regime, a student is evaluated in terms of their ability to demonstrate application of a body of knowledge to a scenario situated in an actual, or a near replica of a real-world context. At Universitas 21 Global (U21Global), a completely online graduate school backed by 16 universities from around the world, the entire pedagogical model is founded on such an approach. One unique feature of the U21Global model is its interactive examination instrument which harnesses the power of the various information and communication technologies (ICTs). This instrument, referred to as the Open-Book Open-Web (OBOW) exam, presents students with a description of a simulated business problem using multimedia. They are then asked to assume a particular role and make recommendations about how to go about solving the problem. Feedback to date indicates that students are generally very positive about OBOW exams. On the minus side, the construction of OBOW exams presents a number of challenges. Not least of these is the steep learning curve it presents for exam authors unaccustomed to working within this paradigm.
Biopterin Status in Dogs with Myxomatous Mitral Valve Disease is Associated with Disease Severity and Cardiovascular Risk Factors

Background Endothelial dysfunction (ED) has been suggested to be associated with myxomatous mitral valve disease (MMVD) in dogs. Tetrahydrobiopterin (BH4) is an important cofactor for production of the endothelium‐derived vasodilator nitric oxide (NO). Under conditions of oxidative stress, BH4 is oxidized to the biologically inactive form dihydrobiopterin (BH2). Thus, plasma concentrations of BH2 and BH4 may reflect ED and oxidative stress. Objective To determine plasma concentrations of BH2 and BH4 in dogs with different degrees of MMVD. Animals Eighty‐four privately owned dogs grouped according to ACVIM guidelines (37 healthy control dogs including 13 Beagles and 24 Cavalier King Charles Spaniels [CKCSs], 33 CKCSs with MMVD of differing severity including 18 CKCSs [group B1] and 15 CKCSs [group B2], and 14 dogs of different breeds with clinical signs of congestive heart failure [CHF] because of MMVD [group C]). Methods Dogs underwent clinical examination including echocardiography. Plasma concentrations of BH2 and BH4 were measured using high‐performance liquid chromatography with fluorescence detection. Results Higher plasma BH4 and BH2 concentrations were found with dogs in CHF compared with all other groups (control, B1 and B2; P ≤ .001). Females had higher concentrations of BH4 and BH4/BH2 (P ≤ .0003). BH4/BH2 was found to decrease with age (P < .0001). Cardiovascular risk factors in humans such as passive smoking (P ≤ .01) and increased body weight (P ≤ .009) were associated with lower BH4 concentrations. Conclusions and Clinical Importance Age, sex, body weight, passive smoking, and cardiac status are associated with plasma biopterin concentration in dogs. Additional studies should clarify the clinical implications of the findings.
Flexible modeling of competing risks in survival analysis

Prognostic studies often involve modeling competing risks, where an individual can experience only one of alternative events, and the goal is to estimate hazard functions and covariate effects associated with each event type. Lunn and McNeil proposed data manipulation that permits extending the Cox's proportional hazards model to estimate covariate effects on the hazard of each competing events. However, the hazard functions for competing events are assumed to remain proportional over the entire follow‐up period, implying the same shape of all event‐specific hazards, and covariate effects are restricted to also remain constant over time, even if such assumptions are often questionable. To avoid such limitations, we propose a flexible model to (i) obtain distinct estimates of the baseline hazard functions for each event type, and (ii) allow estimating time‐dependent covariate effects in a parsimonious model. Our flexible competing risks regression model uses smooth cubic regression splines to model the time‐dependent changes in (i) the ratio of event‐specific baseline hazards, and (ii) the covariate effects. In simulations, we evaluate the performance of the proposed estimators and likelihood ratio tests, under different assumptions. We apply the proposed flexible model in a prognostic study of colorectal cancer mortality, with two competing events: ‘death from colorectal cancer’ and ‘death from other causes’. Copyright © 2010 John Wiley & Sons, Ltd.
Laughter and Dialogue: The Social Significance of Laughter in Institutional Discourse

This study is based interaction in institutional settings (job interviews, post-trial interviews with defendants, negotiations between high-school students, telephone conversations between social-walfare officers and parents) and examines the social significance of laughter in dialogue. As an example, two assumptions put forward by Jefferson (1979, 1984) are questioned—namely, that laughter is regularly triggered by something funny and that laughter always has a strong inviting character. The analyses show that, in dialogue, we often laugh alone and not always at things considered particularly funny. Mutual laughter is a sign of rapport and consensus. This is exemplified by the fact that in the job interviews resulting in a job offer there was more mutual laughter than in those involving applicants who were unsuccessful. Unilateral laughter is used to modify verbal expressions or attitudes and can help us in handling ambiguities and tension.
Emotional labour: clinicians' attitudes to death and dying.

PURPOSE This paper aims to understand the impact of emotional labour in specific health care settings and its potential effect on patient care. DESIGN/METHODOLOGY/APPROACH Multi-method qualitative ethnographic study undertaken in a large ICU in Sydney, Australia using observations from patient case studies, ward rounds and family conferences, open ended interviews with medical and nursing clinicians and managers and focus groups with nurses. FINDINGS Clinician attitudes to death and dying and clinicians' capacity to engage with the human needs of patients influenced how emotional labour was experienced. Negative effects were not formally acknowledged in clinical workplaces and institutional mechanisms to support clinicians did not exist. RESEARCH LIMITATIONS/IMPLICATIONS The potential effects of clinician attitudes on performance are hypothesised from clinician-reported data; no evaluation was undertaken of patient care. PRACTICAL IMPLICATIONS Health service providers must openly acknowledge the effect of emotional labour on the care of dying people. By sharing their experiences, multidisciplinary clinicians become aware of the personal, professional and organisational impact of emotional labour as a core element of health care so as to explicitly and practically respond to it. ORIGINALITY/VALUE The effect of care on clinicians, particularly care of dying people, not only affects the wellbeing of clinicians themselves, but also the quality of care that patients receive. The affective aspect of clinical work must be factored in as an essential element of quality and quality improvement.