Miracle-dz/UniFAR-FTUs huggingface dataset:
Health and Productivity as a Business Strategy: A Multiemployer Study

Objective: To explore methodological refinements in measuring health-related lost productivity and to assess the business implications of a full-cost approach to managing health. Methods: Health-related lost productivity was measured among 10 employers with a total of 51,648 employee respondents using the Health and Work Performance Questionnaire combined with 1,134,281 medical and pharmacy claims. Regression analyses were used to estimate the associations of health conditions with absenteeism and presenteeism using a range of models. Results: Health-related productivity costs are significantly greater than medical and pharmacy costs alone (on average 2.3 to 1). Chronic conditions such as depression/anxiety, obesity, arthritis, and back/neck pain are especially important causes of productivity loss. Comorbidities have significant non-additive effects on both absenteeism and presenteeism. Executives/Managers experience as much or more monetized productivity loss from depression and back pain as Laborers/Operators. Testimonials are reported from participating companies on how the study helped shape their corporate health strategies. Conclusions: A strong link exists between health and productivity. Integrating productivity data with health data can help employers develop effective workplace health human capital investment strategies. More research is needed to understand the impacts of comorbidity and to evaluate the cost effectiveness of health and productivity interventions from an employer perspective.
Broadband Doherty Power Amplifier Based on Asymmetric Load Matching Networks

This brief presents asymmetric load matching networks for broadband Doherty power amplifiers (DPAs). The output combiner consists of two λ/4 impedance transformers with optimized characteristic impedance values in order to provide a load modulation at a high output power level; the bandwidth limitation for efficiency at the back-off power level can be then mitigated. For a proper load modulation with the proposed output combiner, asymmetric load matching networks between the carrier and peaking amplifiers are proposed. The input and output matching networks were designed using balanced open stubs, which are more insensitive to frequency than unbalanced open stubs. For the load matching networks, two-section matching networks were adopted. The designed and implemented broadband DPA showed a fractional bandwidth of 23.5% (from 750 to 950 MHz). It also showed measured efficiency values of higher than 55.4% at the peak power level and 51.5% at the 6-dB back-off power level, respectively. For the operational frequency range, a peak output power value of higher than 48 dBm and a gain of 14-15.8 dB were achieved.
Glucose-6 Phosphate Dehydrogenase Deficiency and Psychotic Illness

Mr. T, a 28-year-old unmarried male, a diagnosed case of Glucose-6 Phosphate Dehydrogenase (G6PD) deficiency since childhood, presented with 13 years of psychotic illness and disturbed biological functions. He showed poor response to antipsychotics and mood stabilizers and had three prior admissions to Psychiatry. There was a family history of psychotic illness. The General Physical Examination and Systemic Examination were unremarkable. Mental Status Examination revealed increased psychomotor activity, pressure of speech, euphoric affect, prolixity, delusion of persecution, delusion of grandiosity, delusion of control, thought withdrawal and thought insertion, and second and third person auditory hallucinations, with impaired judgment and insight. A diagnosis of schizophrenia paranoid type, with a differential diagnosis of schizoaffective disorder manic subtype, was made. This case is being reported for its rarity and atypicality of clinical presentation, as well as a course of psychotic illness in the G6PD Deficiency state,with its implications on management.
Genetic Contributions to Antisocial Personality and Behavior: A Meta-Analytic Review From an Evolutionary Perspective

ABSTRACT Evidence from behavioral genetics supports the conclusion that a significant amount of the variance in antisocial personality and behavior (APB) is due to genetic contributions. Many scientific fields such as psychology, medicine, and criminal justice struggle to incorporate this information with preexisting paradigms that focused exclusively on external or learned etiology of antisocial behavior. The current paper presents a meta-analytic review of behavioral genetic etiological studies of APB. Results indicated that 56% of the variance in APB can be explained through genetic influences, with 11% due to shared non-genetic influences, and 31% due to unique non-genetic influences. This data is discussed in relation to evolutionary psychological theory.
Localized magnetorotational instability and its role in the accretion disc dynamo

The magnetorotational instability (MRI) is believed to be an efficient way to transport angular momentum in accretion discs. It has also been suggested as a way to amplify magnetic fields in discs, the instability acting as a non-linear dynamo. Recent numerical work has shown that a large-scale magnetic field, which is predominantly azimuthal, axisymmetric and has zero net flux, can be sustained by motions driven by the MRI of this same field. Following this idea, we present an analytical calculation of the MRI in the presence of an azimuthal field with a non-trivial vertical structure. In the limit of small vertical wavelengths, we show that magnetorotational shearing waves have the form of vertically localized wavepackets that follow the classical MRI dispersion relation to a first approximation. We determine analytically the spatiotemporal evolution of these wavepackets and calculate the associated mean electromotive force (EMF), which results from the correlation of the velocity and magnetic field perturbations. The vertical structure of the azimuthal field results in a radial EMF that tends to reduce the magnetic energy, acting like a turbulent resistivity by mixing the non-uniform azimuthal field. Meanwhile, the azimuthal EMF generates a radial field that, in combination with the Keplerian shear, tends to amplify the azimuthal field and can therefore assist in the dynamo process. This effect, however, is reversed for sufficiently strong azimuthal fields, naturally leading to a saturation of the dynamo and possibly to a cyclic behaviour of the magnetic field. We compare these findings with numerical solutions of the linearized equations in various approximations, and show them to be compatible with recent non-linear simulations of a MRI dynamo.
Sequence divergence in the Treponema denticola FhbB protein and its impact on factor H binding.

Treponema denticola is an anaerobic spirochete whose abundance in the subgingival crevice correlates with the development and severity of periodontal disease. The ability of T. denticola to survive and thrive in the hostile environment of the periodontal pocket is due, at least in part, to its ability to bind factor H (FH), a negative regulator of the alternative complement pathway. The FH binding protein of T. denticola has been identified as FhbB and its atomic structure has been determined. The interaction of FH with T. denticola is unique in that FH bound to the cell surface is cleaved by the T. denticola protease, dentilisin. It has been postulated that FH cleavage by T. denticola leads to immune dysregulation in periodontal pockets. In this study, we conduct a comparative assessment of the sequence, properties, structure and ligand binding kinetics of the FhbB proteins of strains 33521 and 35405. The biological outcome of the interaction of these strains with FH could differ significantly as 33521 lacks dentilisin activity. The data presented here offer insight into our understanding of the interactions of T. denticola with the host and its potential to influence disease progression.
Adaptive Eigenvalue Computation - Complexity Estimates

This paper is concerned with the design and analysis of a fully adaptive eigenvalue solver for linear symmetric operators. After transforming the original problem into an equivalent one formulated on $\ell_2$, the space of square summable sequences, the problem becomes sufficiently well conditioned so that a gradient type iteration can be shown to reduce the error by some fixed factor per step. It then remains to realize these (ideal) iterations within suitable dynamically updated error tolerances. It is shown under which circumstances the adaptive scheme exhibits in some sense asymptotically optimal complexity.
Filtration Properties of Nonwoven Structures with Superabsorbents for Respiratory Protective Devices

The paper presents a study of the protective and functional properties of nonwoven structures, such as penetration by solid and liquid aerosols, airflow resistance, and air moisture sorption capacity. Nonwovens were modified by the introduction of electrostatic charges in the structure of polymer fibers and by the addition of a superabsorbent polymer (SAP) directly to the fiber-forming area in a melt-blown process. The resulting materials (outer nonwovens containing SAP of different grain sizes and filtering nonwovens with and without electrostatic charges) had varied morphological structures. The materials developed were characterised by high filtering efficiency at low airflow resistance and good moisture sorption ability. The study proved the possibility to apply nonwoven structures containing SAP in respiratory protective equipment used in harsh work environments at high temperature and relative humidity. The materials fabricated were found to improve hygienic comfort.
Sooner or later? Issues in the early diagnosis of dementia in general practice: a qualitative study.

OBJECTIVE The aim of this study was to explore the perspectives of primary care practitioners on the early diagnosis of dementia. METHODS A total of 247 GPs, 146 community nurses, 36 practice nurses, 79 community mental health nurses and others working in a range of hospital, residential and community settings attended 24 one-day workshops in 21 cities and towns in the UK. A nominal group approach was used relating to the early diagnosis of dementia in the community. RESULTS Groups agreed on the benefits and risks of early diagnosis of dementia; disagreed about screening for dementia, and about professional resistance to making the diagnosis; constructed comprehensive guidelines on diagnosis, but without much reference to resource implications; yet described actual local resource limitations in detail; and avoided dilemmas about dementia care by framing it as a specialist activity. CONCLUSION Practitioners situate dementia in a family context but do not yet use a disablement model of dementia which might reduce tensions about early diagnosis and the disclosure of the diagnosis. The term diagnosis could usefully be replaced by recognition, to aid this shift in model. Service gaps may emerge or widen if earlier diagnosis of dementia is pursued as a policy objective.
Accuracy of Transnasal Cannulation and Dilation of the Maxillary Ostium in Cadavers with Intact Uncinates

Background Transnasal cannulation of the natural ostium in patients with an intact uncinate process is complicated by the lack of direct visualization of the ostium. Accuracy of transnasal dilation of the maxillary ostium was evaluated for a malleable-tipped balloon device that was bent to specific angles for avoiding the fontanelle during cannulation. Methods Transnasal cannulation and dilation of 42 cadaver maxillary sinus ostia was attempted by 6 surgeons including 3 with very limited clinical experience using the study device. All physicians received procedure training including the technique to shape the balloon device into the recommended 135° maxillary configuration. Tissue dissection was prohibited. Canine fossa trephination and transantral endoscopy were used to evaluate cannulation and dilation outcomes. Physician operators were blinded to transantral images and results were documented by two observers. Results Appropriate transnasal cannulation and dilation of natural maxillary sinus ostia occurred in 92.9% (39/42) of attempts. Two failures emanated from procedural deviations. In one deviation, the bend angle was changed to 90° and the device tip did not cannulate the ostium. In the second, the device was passed through a preexisting hole in the uncinate and cannulated the natural ostium. A third failure occurred when the device was passed through the fontanelle creating a false lumen. Conclusion Using recommended procedural techniques and a malleable-tipped balloon device, newly trained and experienced physicians alike can perform uncinate-preserving transnasal cannulation and dilation of the maxillary ostium with a high rate of success.
Improvement of the Mechanical Properties of 30MnB5 Wear-Resistant Steel by Subcritical Annealing and Water Quenching, Improving Its Life Cycle Analysis

Life Cycle Analysis (carbon footprint) is currently a criterion that should accompany the selection of materials and processes. This research proposes a heat treatment for carbon steels with boron and manganese that reduces processing time and saves energy. It is a question of replacing the conventional hardening and tempering treatment with a single stage of subcritical annealing and hardening. This can be achieved thanks to the presence of boron in the steel, which significantly increases its hardening capacity. Thus, 30MnB5 carbon steel, with a very short subcritical annealing time and water hardening, competes in advantages with other wear-resistant steels such as RAEX450. The Life Cycle Analysis (carbon footprint) is very favorable and, its mechanical properties very advantageous, within the field of application of these steels. The obtaining of a dual-phase ferrite-martensite structure, with this heat treatment, allows very positive mechanical characteristics and adaptable to a variety of possibilities. *Corresponding author: Laura García Sanchez, Department of Materials and Chemicals Engineering, Complutense University of Madrid, Spain, Tel: +34914 520400; E-mail: gslaura@quim.ucm. es Received October 09, 2018; Accepted October 20, 2018; Published October 31, 2018 Citation: Queirós GW, Bermejo J, Garcia Sanchez L, Gómez Salazar JM, Criado AJ (2018) Improvement of the Mechanical Properties of 30MnB5 Wear-Resistant Steel by Subcritical Annealing and Water Quenching, Improving Its Life Cycle Analysis. J Material Sci Eng 7: 495. doi: 10.4172/2169-0022.1000495 Copyright: © 2018 Queirós GW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Cyclotron resonance and photoluminescence studies of dilute GaAsN in magnetic fields up to 62 Tesla

In this thesis, we investigate optical and electrical properties of dilute nitride semiconductors GaAsN in pulsed magnetic fields up to 62 T. For the most part, the experiments are performed at the Dresden High Magnetic Field Laboratory (HLD). In the first part of this thesis, the electron effective mass of GaAsN is determined with a direct method for the first time. Cyclotron resonance (CR) absorption spectroscopy is performed in Si-doped GaAsN epilayers with a nitrogen content up to 0.2%. For the CR absorption study, we use the combination of the free-electron laser FELBE and pulsed magnetic fields at the HLD, both located at the Helmholtz-Zentrum Dresden-Rossendorf. A slight increase of the CR electron effective mass with N content is obtained. This result is in excellent agreement with calculations based on the band anticrossing model and the empirical tight-binding method. We also find an increase of the band nonparabolicity with increasing N concentration in agreement with our calculations of the energy dependent momentum effective mass. In the second part of this thesis, the photoluminescence (PL) characteristics of intrinsic GaAsN and n-doped GaAsN:Si is studied. The PL of intrinsic and very dilute GaAsN is characterized by both GaAs-related transitions and N-induced features. These distinct peaks merge into a broad spectral band of localized excitons (LEs) when the N content is increased. This so-called LE-band exhibits a partially delocalized character because of overlapping exciton wave functions and an efficient interexcitonic population transfer. Merged spectra dominate the PL of all Si-doped GaAsN samples. They have contributions of free and localized excitons and are consequently blue-shifted with respect to LE-bands of intrinsic GaAsN. The highly merged PL profiles of GaAsN:Si are studied systematically for the first time with temperature-dependent time-resolved PL. The PL decay is predominantly monoexponential and has a strong energy dispersion. In comparison to formerly reported values of intrinsic GaAsN epilayers, the determined decay times of GaAsN:Si are reduced by a factor of 10 because of enhanced Shockley-Read-Hall and possibly Auger recombinations. In the third part of this thesis, intrinsic and Si-doped GaAsN are investigated with magneto-PL in fields up to 62 T. A magneto-PL setup for pulsed magnetic fields of the HLD was built for this purpose. The blue-shift of LE-bands is studied in high magnetic fields in order to investigate its delocalized character. The blue-shift is diminished in intrinsic GaAsN at higher temperatures, which indicates that the interexcitonic
G-Boxes, Bigfoot Genes, and Environmental Response: Characterization of Intragenomic Conserved Noncoding Sequences in Arabidopsis[W]

A tetraploidy left Arabidopsis thaliana with 6358 pairs of homoeologs that, when aligned, generated 14,944 intragenomic conserved noncoding sequences (CNSs). Our previous work assembled these phylogenetic footprints into a database. We show that known transcription factor (TF) binding motifs, including the G-box, are overrepresented in these CNSs. A total of 254 genes spanning long lengths of CNS-rich chromosomes (Bigfoot) dominate this database. Therefore, we made subdatabases: one containing Bigfoot genes and the other containing genes with three to five CNSs (Smallfoot). Bigfoot genes are generally TFs that respond to signals, with their modal CNS positioned 3.1 kb 5′ from the ATG. Smallfoot genes encode components of signal transduction machinery, the cytoskeleton, or involve transcription. We queried each subdatabase with each possible 7-nucleotide sequence. Among hundreds of hits, most were purified from CNSs, and almost all of those significantly enriched in CNSs had no experimental history. The 7-mers in CNSs are not 5′- to 3′-oriented in Bigfoot genes but are often oriented in Smallfoot genes. CNSs with one G-box tend to have two G-boxes. CNSs were shared with the homoeolog only and with no other gene, suggesting that binding site turnover impedes detection. Bigfoot genes may function in adaptation to environmental change.
Silk‐Based Fine Dust Filters for Air Filtration

State‐of‐the‐art air filter devices have been well‐characterized and optimized for particle deposition of a huge range of particle sizes. However, sustainability of the employed filter materials is usually neglected. In this study, several polymers (recombinant spider silk, recombinant lacewing silk, poly(lactic acid), and poly(ethylene oxide)) are electrospun into fine dust filter layers to evaluate relevant filter parameters such as particle deposition, air permeability, and pressure drop for sub‐micrometer fiber materials. Filters comprising silk proteins show a much lower demand on fine‐dust‐layer material (40–210 mg m−2) in comparison to that of conventional filters (50 g m−2). Filters equipped with silk meshes with fiber diameters in the sub‐micrometer regime (<250 nm) show improved filter qualities in comparison to that of commercially available air filter devices (with melt blown fibers in the >20 µm regime). In particular, sub‐micrometer particles (0.2–1 µm) are filtered more efficiently by the silk‐based filters due to interception and impaction effects yielding a low pressure drop, and therefore these filters show an improved air permeability and lowered pressure drop of, for example, a vacuum cleaner bag in which they can be employed.
On a Certain Generalization of the Balog-Szemerédi-Gowers Theorem

In the present paper we give a generalization of the Balog–Szemeredi–Gowers theorem for multiple sumsets A+A+⋯+A. Furthermore, the bounds we develop (on the rate of growth of certain subsums A′+A′+⋯+A′ as a function of k, the number of copies of A′ we add together) are almost the best possible.
Limits on the location of planetesimal formation in self-gravitating protostellar discs

In this Letter, we show that if planetesimals form in spiral features in self-gravitating discs, as previously suggested by the idealized simulations of Rice et al., then in realistic protostellar discs, this process will be restricted to the outer regions of the disc (i.e. at radii in excess of several tens of au). This restriction relates to the requirement that dust has to be concentrated in spiral features on a time-scale that is less than the (roughly dynamical) lifetime of such features, and that such rapid accumulation requires spiral features whose fractional amplitude is not much less than unity. This in turn requires that the cooling time-scale of the gas is relatively short, which restricts the process to the outer disc. We point out that the efficient conversion of a large fraction of the primordial dust in the disc into planetesimals could rescue this material from the well-known problem of rapid inward migration at an approximate metre-size scale and that in principle the collisional evolution of these objects could help to resupply small dust to the protostellar disc. We also point out the possible implications of this scenario for the location of planetesimal belts inferred in debris discs around main sequence stars, but stress that further dynamical studies are required in order to establish whether the disc retains a memory of the initial site of planetesimal creation.
Flexible MXene/Carbon Nanotube Composite Paper with High Volumetric Capacitance

Free-standing and flexible sandwich-like MXene/carbon nanotube (CNT) paper, composed of alternating MXene and CNT layers, is fabricated using a simple filtration method. These sandwich-like papers exhibit high volumetric capacitances, good rate performances, and excellent cycling stability when employed as electrodes in supercapacitors.
Genomic duplication in Dyggve Melchior Clausen syndrome, a novel mutation mechanism in an autosomal recessive disorder

Background: Dyggve Melchior Clausen syndrome (DMC) is a severe autosomal recessive skeletal dysplasia associated with mental retardation. Direct sequencing of genomic DNA has identified causative mutations in the gene Dymeclin (chromosome 18q12–21), with the majority predicting the generation of a truncated protein product. Objective: To carry out molecular genetic studies in three DMC kindreds. Results: Two novel nonsense mutations and two complex genomic duplication events resulting in exon repetition were identified. Conclusions: Exon dosage assessment or mRNA analysis, in addition to direct genomic DNA sequencing, should be employed in the investigation of DMC affected individuals. Genomic duplication may be the causative mutation mechanism in other autosomal recessive disorders.