Miracle-dz/UniFAR-FTUs huggingface dataset:
Antioxidant Capacities and Total Phenolic Contents Increase with Gamma Irradiation in Two Types of Malaysian Honey

Two types of monofloral Malaysian honey (Gelam and Nenas) were analyzed to determine their antioxidant activities and total phenolic and flavonoid contents, with and without gamma irradiation. Our results showed that both types of honey can scavenge free radicals and exhibit high antioxidant-reducing power; however, Gelam honey exhibited higher antioxidant activity (p < 0.05) than Nenas honey, which is in good correlation (r = 0.9899) with its phenolic contents. Interestingly, we also noted that both irradiated honeys have higher antioxidant activities and total phenolic and flavonoid contents compared to nonirradiated honeys by Folin-Ciocalteu and UV-spectrophotometry methods, respectively. However, HPLC analysis for phenolic compounds showed insignificant increase between irradiated and nonirradiated honeys. The phenolic compounds such as: caffeic acid, chlorogenic acid, ellagic acid, p- coumaric acid, quercetin and hesperetin as indicated by HPLC method were found to be higher in Gelam honey versus Nenas honey. In conclusion, irradiation of honey causes enhanced antioxidant activities and flavonoid compounds.
Edge transport in the trivial phase of InAs/GaSb

We present transport and scanning SQUID measurements on InAs/GaSb double quantum wells, a system predicted to be a two-dimensional topological insulator. Top and back gates allow independent control of density and band offset, allowing tuning from the trivial to the topological regime. In the trivial regime, bulk conductivity is quenched but transport persists along the edges, superficially resembling the predicted helical edge-channels in the topological regime. We characterize edge conduction in the trivial regime in a wide variety of sample geometries and measurement configurations, as a function of temperature, magnetic field, and edge length. Despite similarities to studies claiming measurements of helical edge channels, our characterization points to a non-topological origin for these observations.
A Location-Determination Application in WirelessHART

WirelessHART is an emerging wireless communication standard that is targeted at the real-time process control industry.An example application of wireless communication in an industrial process control plant is the location of field engineers. The capability to locate personnel is a safety critical issue in process control plants because of high risks posed by toxic chemicals and other hazards. This paper presents the design, implementation and evaluation of a location-aware application built upon WirelessHART. The aim of this application is to locate a mobile device (and thus the person carrying the device) via the deployed WirelessHART network. The application is a software-based – no device modifications are required. Consequently, it is applicable to any WirelessHART network. In this application, both the mobile device (a handheld device or a badge carried by a worker) and field devices (attached to the plant process) periodically send health reports of their neighbors to the network manager. The network manager analyzes these reports and discards the untrustworthy pairs through comparison. Next, the network manager feeds the average received signal indications to a well-trained radio propagation model to derive the location. To evaluation our solution, several preliminary experiments are carried out and the results are very promising, with a median error less than 4 meters, which is good enough for the industrial requirement. To the best of our knowledge, this is the first attempt to develop location-aware application in WirelessHART networks.
Relationships between Regular and Irregular Collective Communication Operations on Clustered Multiprocessors

We characterize collective communication operations on (clustered) multiprocessor systems in terms of their communication volume, and arrive at useful relationships between regular and irregular operations over sets of processors and sets of cluster-nodes, respectively. We show that regular problems over sets of processors induce corresponding irregular problems over sets of nodes. We hereby identify a symmetric variant of the personalized all-to-all communication problem that might be worth studying in its own right, and discuss an algorithm for solving this problem. From a simple algorithm for the regular all-gather problem over sets of processors, we derive an algorithm for the irregular all-gather problem over both sets of processors and sets of nodes. For communication libraries like MPI, the relationships emphasize the need for efficient algorithms for the irregular collective communication operations.
INTERIOR NOISE OF A KOREAN HIGH-SPEED TRAIN IN TUNNELS

High-speed trains with the maximum speed of 300 km/h, named as Korea Train Express (KTX), have started revenue services since April 2004. Because of the geomorphologic conditions of Korea a large portion of the ‘Kyung-Bu’ line is comprised of tunnels or bridges, which may cause excessive noise in a vehicle. The vibration generated by the trains propagates into the tunnel and the vehicle structure and it can be radiated as noise inside the vehicle interior. This noise can usually be heard as low frequency structure-borne noise. Measurement of the noise and vibration inside the KTX vehicle confirmed that the noise comprises of frequencies below 250 Hz with a couple of broad peaks. In this study the analysis has been presented to reveal the cause of the excessive noise level and the correlation between the vehicle interior noise and the vibration of the tunnel structure.
Duelling timescales of host mixing and disease spread determine invasion of disease in structured populations

The epidemic potential of a disease is traditionally assessed using the basic reproductive number, R0. However, in populations with social or spatial structure a chronic disease is more likely to invade than an acute disease with the same R0, because it persists longer within each group and allows for more host movement between groups. Acute diseases ‘perceive’ a more structured host population, and it is more important to consider host population structure in analyses of these diseases. The probability of a pandemic does not arise independently from characteristics of either the host or disease, but rather from the interaction of host movement and disease recovery timescales. The R* statistic, a group-level equivalent of R0, is a better indicator of disease invasion in structured populations than the individual-level R0.
Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface

Membrane type 1-matrix metalloproteinase (MT1-MMP) is an integral type I transmembrane multidomain zinc-dependent endopeptidase involved in extracellular matrix remodelling in physiological as well as pathological processes. MT1-MMP participates in the regulated turnover of various extracellular matrix components as well as the activation of secreted metalloproteinases and the cleavage of various cell membrane components. MT1-MMP expression has been reported to correlate with the malignancy of various tumour types and is thought to be an important mediator of cell migration and invasion. Recently, it has been proposed that internalisation of the enzyme from the cell surface is a major short-term level of MT1-MMP regulation controlling the net amount of active enzyme present at the plasma membrane. In this paper we show that, in HT1080 fibrosarcoma cells, MT1-MMP is internalised from the cell surface and colocalises with various markers of the endocytic compartment. Interestingly, we observed that in these cells, internalisation occurs by a combination of both clathrin-mediated and -independent pathways, most probably involving caveolae. In addition, internalised MT1-MMP is recycled to the cell surface, which could, in addition to downregulation of the enzymatic activity, represent a rapid response mechanism used by the cell for relocalising active MT1-MMP at the leading edge during migration.
Response of the flow dynamics of Bowdoin Glacier, northwestern Greenland, to basal lubrication and tidal forcing

ABSTRACT We use the full-Stokes model Elmer/Ice to investigate the present dynamics of Bowdoin Glacier, a marine-terminating outlet glacier in northwestern Greenland. Short-term speed variations of the glacier were observed, correlating with air temperature and precipitation, and with the semi-diurnal ocean tides. We use a control inverse method to determine the distribution of basal friction. This reveals that most of the glacier area is characterized by near-plug-flow conditions, while some sticky spots are also identified. We then conduct experiments to test the sensitivity of the glacier flow to basal lubrication and tidal forcing at the calving front. Reduction of the basal drag by 10–40% produces speed-ups that agree approximately with the observed range of speed-ups that result from warm weather and precipitation events. In agreement with the observations, tidal forcing and surface speed near the calving front are found to be in anti-phase (high tide corresponds to low speed, and vice versa). However, the amplitude of the semi-diurnal variability is underpredicted by a factor ~ 3, which is likely related to either inaccuracies in the surface and bedrock topographies or mechanical weakening due to crevassing.
Clinal variation in stomatal characteristics of an Arctic sedge, Eriophorum vaginatum (Cyperaceae).

PREMISE OF THE STUDY In a large reciprocal transplant experiment, Eriophorum vaginatum tussocks transplanted along a latitudinal gradient in Alaska's interior exhibited genetic differentiation and phenotypic plasticity for vegetative traits. Using the same tussocks 30 yr later, we used estimates of growing season temperature at each site to ask whether there was a climatic cline for stomatal density, size, and conductance. METHODS We created impressions of the abaxial leaf surfaces of the transplanted individuals for viewing under a microscope and measured stomatal density (SD) and length (SL) for 224 individuals. We used SD and SL to estimate stomatal conductance (C). Separate one-way analyses of variance were performed to quantify the effect of population genetic differences and latitudinal environmental variation on stomatal characteristics. KEY RESULTS Our data suggest that stomatal size was influenced by both genetics and environment and that plasticity for stomatal density produced highest densities at the coolest sites. Stomatal conductance increased with decreasing temperature of site from which the populations originated. CONCLUSIONS Our results demonstrate a cline in stomatal conductance in E. vaginatum, with some ability of populations to plastically produce an appropriate phenotypic response in a new environment. Because the species is a dominant species in many arctic plant communities, its ability to produce an appropriate stomatal phenotype and to optimize water use efficiency by decreasing stomatal conductance in warmer environments could affect both community composition and total primary productivity in future, warmer climates.
Biodiversity and Phenology of the Epibenthic Macroinvertebrate Fauna in a First Order Mississippi Stream

iv ACKNOWLEDGMENTS . vi LIST OF ILLUSTRATIONS . x CHAPTER I INTRODUCTION . 1 Study Site and Study Hypothesis . 4 CHAPTER II METHODS . 7 Sampling Methods . 7 Data Analysis . 10 Taxonomic Literature and Notes . 12 CHAPTER III – RESULTS . 14 Plecoptera . 23 Ephemeroptera . 23 Trichoptera . 24 Coleoptera, Odonata, and Megaloptera . 25 CHAPTER IV – DISCUSSION . 34 APPENDIX A . 42 APPENDIX B – Aquatic insect order numbers (excluding family Chironomidae) for the Hester-Dendy multiplate and stick/leaf samples in Granny Creek for 12 sampling dates
Evaluation of adjunctive tests for cervical cancer screening in low resource settings.

BACKGROUND Visual inspection of cervix after application of acetic acid (VIA) is an effective screening tool for cervical cancer in low resource settings, but its low specificity leads to high referral rates. Adjunctive testing may overcome this drawback. AIMS This pilot study was aimed to assess test performances of VIA, human papillomavirus (HPV) testing and Pap smear, individually and in simulated combinations, to determine the probable best screening option. SETTING AND DESIGN Gynecology outpatient department (OPD); cross-sectional study. MATERIALS AND METHODS One hundred women with complaints of irregular vaginal bleeding or discharge, post coital bleeding or unhealthy cervix on examination underwent Pap smear, HPV testing, VIA, colposcopy and biopsy, if indicated, in this screening order. STATISTICAL ANALYSIS Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for each of the tests with a biopsy result of > or =HSIL taken as the gold standard. Simulated parallel and sequential combinations for VIA/Pap, VIA/HPV and HPV/Pap were calculated and compared with individual test performance. RESULTS Prevalence of abnormal Pap smears was 5%, VIA positive 51% and HPV positive 16%. Sensitivity and specificity of VIA were 100% and 53.3% respectively. For HPV and Pap tests corresponding figures were 85.7%, 89.7% and 50%, 98.9% respectively. The best simulated combination with a balance of sensitivity and specificity was of VIA followed by HPV testing (sensitivity 85.7%, specificity 95.4%). CONCLUSION Addition of HPV testing to VIA can increase the specificity of VIA, thereby reducing the referral rates without compromising the sensitivity of the test.
General practitioner assessment of structured oncological information accompanying newly referred cancer patients

Scand J Prim Health Care 2003;21:00-00. ISSN 0281-3432 Objective r - r To investigate general practitioner (GP) assessment of a structured oncology information pack sent to GPs when newly referred patients had visited a department of oncology for the first time, and to compare their assessment of this material with their assessment of traditional information provided by the department. Design r - r Randomised, unblinded clinical trial. Setting r - r Patients and GPs in the catchment area of a regional oncology department. Subjects / patients r - r 248 cancer patients and their 199 GPs. Main outcome measures r - r GP assessment of the quality of the information material received for each patient. Results r - r 88.3% of the 248 questionnaires were returned. The structured information pack improved GP knowledge of oncology; GPs found themselves better equipped to support and counsel patients during the course of their illness, and practitioner satisfaction with the department rose. Conclusion r - r Intervention, though reasonably simple, inexpensive and not particularly time-consuming, improved cooperation between the specialist department and the GP. While this is a small step in the right direction, the need remains for new initiatives and further studies into how to improve cooperation and communication between the primary and secondary healthcare sectors.
Common Features of Neural Activity during Singing and Sleep Periods in a Basal Ganglia Nucleus Critical for Vocal Learning in a Juvenile Songbird

Reactivations of waking experiences during sleep have been considered fundamental neural processes for memory consolidation. In songbirds, evidence suggests the importance of sleep-related neuronal activity in song system motor pathway nuclei for both juvenile vocal learning and maintenance of adult song. Like those in singing motor nuclei, neurons in the basal ganglia nucleus Area X, part of the basal ganglia-thalamocortical circuit essential for vocal plasticity, exhibit singing-related activity. It is unclear, however, whether Area X neurons show any distinctive spiking activity during sleep similar to that during singing. Here we demonstrate that, during sleep, Area X pallidal neurons exhibit phasic spiking activity, which shares some firing properties with activity during singing. Shorter interspike intervals that almost exclusively occurred during singing in awake periods were also observed during sleep. The level of firing variability was consistently higher during singing and sleep than during awake non-singing states. Moreover, deceleration of firing rate, which is considered to be an important firing property for transmitting signals from Area X to the thalamic nucleus DLM, was observed mainly during sleep as well as during singing. These results suggest that songbird basal ganglia circuitry may be involved in the off-line processing potentially critical for vocal learning during sensorimotor learning phase.
Gender, Age, and Place of Residence as Moderators of the Internalized Homophobia-Depressive Symptoms Relation Among Australian Gay Men and Lesbians

Internalized homophobia is a risk factor for depression among gay men and lesbians. The aim of the study was to test whether the internalized homophobia-depression relation was moderated by gender (stronger among gay men compared with lesbians), age (stronger among younger compared with older gay men and lesbians), and place of residence (stronger among gay men and lesbians who live in rural areas compared with those who live in urban areas). An Australian sample of 311 self-identified gay men and 570 self-identified lesbians, aged 18 to 70 years, completed the Internalized Homophobia Scale and the Centre for Epidemiological Studies Depression Scale. Results indicated that age and gender did not moderate the internalized homophobia-depressive symptoms relation. Place of residence was a significant moderator for gay men but not lesbians. In contrast to the hypothesis, the internalized homophobia-depression relation was significant only among gay men who resided in urban areas. Those who work with gay men should be particularly aware of the significant relationship between internalized homophobia and depressive symptoms among gay men who reside in urban areas.
Trapped river otters (Lontra canadensis) from central Saskatchewan exhibit differences in total and organic mercury concentrations with sex and geographic location

Human activities have resulted in increasing amounts of mercury Hg(II) in the atmosphere, oceans, and terrestrial systems. Biological processes convert inorganic forms of mercury released into the atmosphere into the neurotoxic and bioaccumulating methylmercury (MeHg) species resulting in increased concern for Hg emissions entering the biosphere. Once deposited from the atmosphere, in-situ methylation of inorganic Hg in sediments is believed to be the largest source of MeHg to freshwater aquatic systems compared to input from the terrestrial environment (i.e. run-off) or atmospheric deposition. Methylation of Hg is predominantly a microbial mediated process that is facilitated by some sulfate and iron reducing bacteria, as well as methanogens. Biological activity, nutrient availability, pH, temperature, redox potential, and the presence of inorganic and organic complexing agents have significant effects on rates of methylation. Degradation of MeHg can occur as well, so that the amount of MeHg available to organisms is a result of two opposing processes. Mink (Mustela vison) and otter (Lontra canadensis) are the most studied mammalian wildlife species with regard to Hg exposure and toxicity. Data indicate that consumption of diets that contained Hg (as MeHg) >1 mg kg -1 wet weight can cause neurotoxicity and death in adult mink and otter. Neurological signs in MeHg-intoxicated mammals typically include lethargy, ataxia, limb paralysis, tremors, convulsions, and ultimately death. Here, I measured Hg concentrations in fur, liver and kidney tissues removed from river otters (Lontra canadensis) collected from trappers in central Saskatchewan (n = 203) over two trapping seasons. Total Hg (THg) concentrations measured in otter tissues were consistent with tissues measured in other non-impacted
Mitochondria: A Therapeutic Target for Parkinson’s Disease?

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. The exact causes of neuronal damage are unknown, but mounting evidence indicates that mitochondrial-mediated pathways contribute to the underlying mechanisms of dopaminergic neuronal cell death both in PD patients and in PD animal models. Mitochondria are organized in a highly dynamic tubular network that is continuously reshaped by opposing processes of fusion and fission. Defects in either fusion or fission, leading to mitochondrial fragmentation, limit mitochondrial motility, decrease energy production and increase oxidative stress, thereby promoting cell dysfunction and death. Thus, the regulation of mitochondrial dynamics processes, such as fusion, fission and mitophagy, represents important mechanisms controlling neuronal cell fate. In this review, we summarize some of the recent evidence supporting that impairment of mitochondrial dynamics, mitophagy and mitochondrial import occurs in cellular and animal PD models and disruption of these processes is a contributing mechanism to cell death in dopaminergic neurons. We also summarize mitochondria-targeting therapeutics in models of PD, proposing that modulation of mitochondrial impairment might be beneficial for drug development toward treatment of PD.
Intact rock bridge breakage and rock mass fragmentation upon failure: quantification using remote sensing techniques

In this work, two processes related to the onset and the evolution of large‐scale rockfalls have been analysed by means of remote sensing techniques. First, the number of rock bridges as a proportion of pre‐existing fractures has been estimated in a newly formed landslide scarp by analysing the spectral information of the rock mass in terrestrial laser scanner (TLS) and unmanned aerial vehicle (UAV) photogrammetric point clouds. Second, the fragmentation of the rock mass after failure has been assessed by comparing the percentage of newly formed fractures in the scarp and in the deposit. For this purpose, an orthophoto of the landslide deposit was classified using an object‐based method. The presented workflow gained new data on the intact rock breakage during and after failure, and consequently deepened knowledge about rock failure and fragmentation mechanisms.