Miracle-dz/UniFAR-FTUs huggingface dataset:
Electron-Ion Recombination Rate Coefficients and Photoionization Cross Sections for Astrophysically Abundant Elements. IV. Relativistic Calculations for C IV and C V for Ultraviolet and X-Ray Modeling

The first complete set of unified cross sections and rate coefficients are calculated for photoionization and recombination of He- and Li-like ions using the relativistic Breit-Pauli R-matrix method. We present total, unified (e + ion) recombination rate coefficients for (e + C ⟶C ) and (e + C ⟶C ), including fine structure. Level-specific recombination rate coefficients up to the n = 10 levels are also obtained for the first time; these differ considerably from the approximate rates currently available. Applications to recombination-cascade coefficients in X-ray spectral models of Kα emission from the important He-like ions are pointed out. The overall uncertainty in the total recombination rates should not exceed 10%-20%. Ionization fractions for carbon are recomputed in the coronal approximation using the new rates. The present (e + ion) recombination rate coefficients are compared with several sets of available data, including previous LS coupling results and "experimentally derived" rate coefficients. The roles of relativistic fine structure, resolution of resonances, radiation damping, and interference effects are discussed. Two general features of recombination rates are noted: (1) the nonresonant (radiative recombination) peak as E,T → 0, and (2) the high-T resonant (dielectronic recombination) peak.
Passiv im Schweizerdeutschen

In this paper, I will show that the investigation of passive constructions by means of written questionnaires ('Projekt Dialektsyntax des Schweizerdeutschen', University of Zurich) provides reliable data on Swiss German dialect syntax. Concerning the accusative passive, I will illustrate that the auxiliaries 'kommen' or 'werden' and inflected or uninflected past participles are found in geographically distinct areas. Our material shows a similar geographical distribution of variants as the data from traditional direct interviews. Since we have been working with several consultants at each place, it is possible to give a picture of the gradual nature of the transition from one to another variant. The distribution of the passive constructions fits more general, North-South-oriented dialect-geographical patterns (cf. Hotzenkocherle 1986) that are well-known from other syntactic phenomena (such as the inflection of the predicative adjective (SDS III 256), of copredicative and resultative constructions (Bucheli Berger/Glaser (2004), Bucheli Berger (2005)). The evidence concerning the dative passive (recipient passive) leads me to the conclusion that its existence is not beyond any doubt in Swiss German. Beside the different passive constructions, I will also discuss the geographical distribution of alternative constructions such as active, 'tun'-periphrasis, etc.
Comparison of peritonsillar infiltration effects of ketamine and tramadol on post tonsillectomy pain: a double-blinded randomized placebo-controlled clinical trial

Aim To assess the effect of peritonsillar infiltration of ketamine and tramadol on post tonsillectomy pain and compare the side effects. Methods The double-blind randomized clinical trial was performed on 126 patients aged 5-12 years who had been scheduled for elective tonsillectomy. The patients were randomly divided into 3 groups to receive either ketamine, tramadol, or placebo. They had American Society of Anesthesiologists physical status class I and II. All patients underwent the same method of anesthesia and surgical procedure. The three groups did not differ according to their age, sex, and duration of anesthesia and surgery. Post operative pain was evaluated using CHEOPS score. Other parameters such as the time to the first request for analgesic, hemodynamic elements, sedation score, nausea, vomiting, and hallucination were also assessed during 12 hours after surgery. Results Tramadol group had significantly lower pain scores (P = 0.005), significantly longer time to the first request for analgesic (P = 0.001), significantly shorter time to the beginning of liquid regimen (P = 0.001), and lower hemodynamic parameters such as blood pressure (P = 0.001) and heart rate (P = 0.001) than other two groups. Ketamine group had significantly greater presence of hallucinations and negative behavior than tramadol and placebo groups. The groups did not differ significantly in the presence of nausea and vomiting. Conclusion Preoperative peritonsillar infiltration of tramadol can decrease post-tonsillectomy pain, analgesic consumption, and the time to recovery without significant side effects. Registration No: IRCT201103255764N2
Haploinsufficiency of Mdm2 and Mdm4 in Tumorigenesis and Development

ABSTRACT The tumor suppressor p53 is inactivated by multiple mechanisms that include mutations of the p53 gene itself and increased levels of the p53 inhibitors MDM2 and MDM4. Mice lacking Mdm2 or Mdm4 exhibit embryo-lethal phenotypes that are completely rescued by concomitant deletion of p53. Here we show that Mdm2 and Mdm4 haploinsufficiency leads to increased p53 activity, exhibited as increased sensitivity to DNA damage and decreased transformation potential. Moreover, in in vivo tumor development, Eμ-myc Mdm4+/− mice show a delayed onset of B-cell lymphomas compared to Eμ-myc mice. Additionally, Mdm2+/−Mdm4+/− double-heterozygous mice are not viable and exhibit defects in hematopoiesis and cerebellar development. The defects in Mdm2+/−Mdm4+/− mice are corrected by deletion of a single p53 allele. These findings highlight the exquisite sensitivity of p53 to Mdm2 and Mdm4 levels and suggest that some cell types may be more sensitive to therapeutic drugs that inhibit the Mdm-p53 interaction.
Linking LMX, innovative work behaviour and turnover intentions

Purpose – This study aims to examine the relationships among leader‐member exchange (LMX), innovative work behaviour (IWB), and intention to quit. The mediating role of work engagement is tested within the relationship of LMX, IWB, and intention to quit.Design/methodology/approach – Respondents to a survey were 979 Indian managerial employees working in six service sector organisations in India. Structural equation modelling was used to test hypothesised relationships.Findings – Results suggest quality of exchanges between employees and their immediate supervisors influences engagement. Work engagement correlates positively with innovative work behaviour and negatively with intention to quit. Work engagement mediates the relationship between LMX and innovative work behaviour, and partially mediates intention to quit.Research limitations/implications – A cross‐sectional design and use of self‐reported questionnaire data is a limitation of this study. Since the study focuses only on service‐sector organisat.
Impact of release intervals on empirical research into software evolution, with application to the maintainability of Linux

In most empirical research on software evolution, analysis of the data is performed with respect to the release sequence number (RSN), rather than the release date. This distinction is important when the intervals between release dates vary widely, as is generally the case with open-source software. A widely cited study on the maintainability of Linux was published in this journal in 2002. The study showed that, whereas the size of the Linux kernel grew linearly with respect to the RSN, the amount of common coupling grew exponentially. In view of the adverse effect of common coupling on maintainability, the conclusion drawn there was that Linux needed to be refactored with minimal common coupling. Here, it is shown that, if the same data are analysed with respect to the release date, the amount of common coupling grows linearly; hence, there is no need to refactor Linux to promote maintainability. The authors also analyse three stable series of Linux releases, and observe that the size and the common coupling grow linearly. The authors conclude that rates of growth should be computed with respect to temporal variables, such as the release date.
Estimation of Total Body Fat and Subcutaneous Adipose Tissue in Full-Term Infants Less Than 3 Months Old

ABSTRACT: Both fetal and neonatal nutrition may influence the body fat content of infants. Epidemiologic field studies would be facilitated by a simple method of measuring total body fat (TBF). The accuracy of a method, based on skinfold measurements, of estimating TBF was evaluated in 22 infants by comparing the results with those obtained by the body water dilution technique. Because the accuracy was poor, a modification was evaluated in 14 of the infants. The measurements were used to calculate the amounts of subcutaneous and nonsubcutaneous body fat. Estimates of the thickness of subcutaneous adipose tissue made with calipers and ultrasonography were compared with each other and with those obtained with Futrex 5000, a device based on the principle of near-infrared interact-ance. The composition of the adipose tissue in biopsy specimen from 38 infants was analyzed and contained a mean of 0.66 g of fat/cm3. Results obtained by Futrex 5000 correlated with subcutaneous adipose tissue thickness only when the latter was thin. Estimates of adipose tissue thickness by calipers were significantly higher than estimates by ultrasonography at the forearm, thigh, and calf, whereas the opposite was found at the triceps, biceps, umbilicus, and nipple. The amount of nonsubcutaneous fat, in relation to body weight minus subcutaneous fat, increased with age and was higher in girls than in boys. Skinfolds were poor predictors of TBF. However, it may be possible to predict TBF from anthropometric measurements if appropriate knowledge about the growth and development of adipose tissue in infancy are available.
Evaluation of Serum Biomarkers for Patients at Increased Risk of Stroke

Early recognition of vulnerable patients is an important issue for stroke prevention. In our study, a multiscore analysis of various biomarkers was performed to evaluate its superiority over the analysis of single factors. Study subjects (n = 110) were divided into four groups: asymptomatic patients with stable (n = 25) and unstable (n = 36) plaques and symptomatic patients with stable (n = 13) and unstable (n = 36) plaques. Serum levels of MMP-1, -2, -3, -7, -8, -9, TIMP-1, -2, TNF-α, IL-1b, and IL-6, -8, -10, -12 were measured. Multi-score analysis was performed using multiple receiver operating characteristics (ROC) and determination of appropriate cutoff values. Significant differences between the groups were observed for MMP-1, -7, -9 and TIMP-1 in serum of the study subjects (P < 0.05). Multiple biomarker analysis led to a significant increase in the AUC (area under curve). In case of plaque instability, positive predictive value (PPV) for up to 86.4% could be correctly associated with vulnerable plaques. Thus, multiscore analysis might be preferable than the use of single biomarkers.
Successful therapeutic vaccination with integrase defective lentiviral vector expressing nononcogenic human papillomavirus E7 protein

Persistent infection with high risk genotypes of human papillomavirus (HPV) is the cause of cervical cancer, one of most common cancer among woman worldwide, and represents an important risk factor associated with other anogenital and oropharyngeal cancers in men and women. Here, we designed a therapeutic vaccine based on integrase defective lentiviral vector (IDLV) to deliver a mutated nononcogenic form of HPV16 E7 protein, considered as a tumor specific antigen for immunotherapy of HPV‐associated cervical cancer, fused to calreticulin (CRT), a protein able to enhance major histocompatibility complex class I antigen presentation (IDLV‐CRT/E7). Vaccination with IDLV‐CRT/E7 induced a potent and persistent E7‐specific T cell response up to 1 year after a single immunization. Importantly, a single immunization with IDLV‐CRT/E7 was able to prevent growth of E7‐expressing TC‐1 tumor cells and to eradicate established tumors in mice. The strong therapeutic effect induced by the IDLV‐based vaccine in this preclinical model suggests that this strategy may be further exploited as a safe and attractive anticancer immunotherapeutic vaccine in humans.
The Sensorimotor Striatum Is Necessary for Serial Order Learning

Central to the production of adaptive behavior is the ability to learn the temporal order of behavioral elements (e.g., A, B, C). Yet little is known about neural substrates of serial order in self-initiated behavioral sequences. The present study assessed the contributions of specific dorsal striatal regions to the acquisition of serial order in mice, using a two-action sequence task without instructive cues. Excitotoxic lesions of the sensorimotor (dorsolateral) striatum dramatically impaired the acquisition of a simple sequence; in contrast, lesions of the associative (dorsomedial) striatum had no significant effect. Neither lesion caused gross motor impairments or affected the learning of nonsequential actions. These results demonstrate for the first time a critical role of the sensorimotor striatum in the learning of serial order.
Family Structure And Maternal Health Trajectories

Existing research shows that marriage and marital stability are positively associated with health and well-being. Thus, recent increases in births to unmarried parents and the instability surrounding these relationships raise concerns about the possible health effects associated with changes in family formation. Using latent trajectory models and data from the Fragile Families and Child Well-Being Study (FFCWS) this paper examines trajectories of mothers’ mental and physical health, specifically focusing on transitions into and out of relationships with the child’s biological father (n = 2,649). Mothers who remain married to their child’s father are in better mental and physical health than continuously cohabiting or continuously single mothers. Among mothers living with the father at birth, exiting a coresidential relationship increases mental health problems and decreases self-rated health. These effects appear to be short-lived, as suggested by stress theory, followed by periods of resilience in the absence of other transitions. Among mothers who are not living with the father, entering a residential relationship improves both mental and physical health, but only prior to the child’s first birthday. The implications of these findings for selection and causation arguments, as well as social policies promoting stable healthy unions between non-married parents, are also discussed.
Investigating working memory and metamemory in old age : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University

An investigation of metamemory for working memory was conducted in a group of older adults aged 60 to 74 years using a variation of the Daneman and Carpenter (1980) reading span task. There were twelve trials in each experiment, with each trial containing six sentences. Participants had to assess whether each sentence was true or false as well as remembering the last word of each sentence in correct order. In Experiment 1 words were phonologically similar (rhyming) and dissimilar (non-rhyming), whereas Experiment 2 presented one syllable (short) words and two syllable (long) words. Half the participants were asked to predict how well they would remember the words and half were asked to postdict how well they had recalled the words. Participants were also asked to complete the Metamemory Functioning Questionnaire (Gilewski, Zelinski & Schaie, 1990) for a self-assessment of memory and this was compared to their memory performance on the recall task. Results indicated that older adults recalled more rhyming words than nonrhyming words, and more short words than long words. They overestimated the number of non-rhyming words they would remember but their estimates fluctuated in the same pattern as actual recall for the rhyming and nonrhyming words showing some accuracy in their metamemory. However, people unexpectedly estimated that they would do better with long than short words. For long words postdictions matched recall better than predictions which showyd that older adults were able to gather information about their performance during the task. There was no correlation between the MFQ scores and the recall accuracy of the memory task probably because the questionnaire measured more general aspects of everyday memory, whereas the recall task-1nvo1ved a single and very specific aspect of memory. When compared to the younger adults the older adults showed poorer recall performance and· ove1estimation-was -targer--for -ofder --a-dults. l'-hese -results I showed us that to some extent, older adults are able to estimate their memory performance, using metamernory-in ·a-complex memory task.
Using adult mosquitoes to transfer insecticides to Aedes aegypti larval habitats

Vector control is a key means of combating mosquito-borne diseases and the only tool available for tackling the transmission of dengue, a disease for which no vaccine, prophylaxis, or therapeutant currently exists. The most effective mosquito control methods include a variety of insecticidal tools that target adults or juveniles. Their successful implementation depends on impacting the largest proportion of the vector population possible. We demonstrate a control strategy that dramatically improves the efficiency with which high coverage of aquatic mosquito habitats can be achieved. The method exploits adult mosquitoes as vehicles of insecticide transfer by harnessing their fundamental behaviors to disseminate a juvenile hormone analogue (JHA) between resting and oviposition sites. A series of field trials undertaken in an Amazon city (Iquitos, Peru) showed that the placement of JHA dissemination stations in just 3–5% of the available resting area resulted in almost complete coverage of sentinel aquatic habitats. More than control mortality occurred in 95–100% of the larval cohorts of Aedes aegypti developing at those sites. Overall reductions in adult emergence of 42–98% were achieved during the trials. A deterministic simulation model predicts amplifications in coverage consistent with our observations and highlights the importance of the residual activity of the insecticide for this technique.
System Reliability and Fault Tree Analysis of SeSHRS-Based Augmentation of Hydrogen: Dedicated for Combined Cycle Power Plants

This paper presents a seven-stage hot redundant structure (SeSHRS)-hydrogen cooling system (HCS), dedicated for cooling of 2 × 660 MW size generators of combined cycle power plants. In the case of large generators, air cooling system restricts itself up to 100 MW generation capacities, while HCS is very effective as a coolant for capacity of 120-130 MW unit(s) and above. To control and monitor such a critical system, it is essential to incorporate supervisory control and data acquisition with HCS for effective cooling of the large generators, and taking proactive actions, if abnormality is observed during the operation. The objectives of this paper are to analyze the system reliability and system failure of the proposed process control and instrumentation of HCS. The work includes a comparison between the proposed and the existing systems in terms of system reliability and fault tree analysis (FTA). The algorithms for system reliability and FTA of the proposed SeSHRS model are developed on the MATLAB platform. The effectiveness of real-time featured proposed HCS is validated by computer simulation. The entire process instrumentation of the system is designed and simulated on RSView Studio, a real-time automation platform by Rockwell Automation, Milwaukee, WI. The proposed design meets the specifications of IEC 61025, IEEE C37.1-2007, and IEEE 1413-2003.
‘What is the impact of birth family contact on children in adoption and long‐term foster care?’ A systematic review

Contact plans for children in adoption and long-term foster care are decided on a case-by-case basis, as directed by the paramountcy principle in the Children Act (1989). The idea that birth family contact helps children resolve issues around attachment, separation and loss, and identity is prevalent in social work practice. However, evidence revealing the detrimental impact of contact has been used to support increasingly restrictive legislation. The current review aims to provide policy-makers and social workers with a resource to guide decisions in permanency planning by evaluating this evidence and reported outcomes for children. The research question and exclusion/inclusion criteria were formulated and used to develop a search strategy. Of the 412 potential titles returned, 11 were of sufficient quality to include in the thematic synthesis. Results were mixed and significantly influenced by moderator variables such as the pre-existing relationship between children and their birth families. Outcomes were particularly positive when there was a collaborative approach between birth families and adoptive parents or foster carers. Outcomes tended to be poorest for children who had ongoing contact with maltreating birth parents. The review findings support current policy and previous research in recommending a more reflexive approach to assessing and planning contact.
Lentiviral-Mediated Silencing of Farnesyl Pyrophosphate Synthase through RNA Interference in Mice

Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The interfering fragment, named pLVT202, was chosen from cardiomyocytes tested in vitro and was microinjected into the perivitelline space of zygotes from C57BL/6J mice via a lentivirus vehicle; 20 were identified as carrying copies of the transgene using the polymerase chain reaction (PCR). Real-time PCR and western blotting analysis showed that FPPS was downregulated in multiple tissues in the transgenic mice. The transgenic mouse model provides a novel means of studying the gene function of FPPS.
The Effectiveness of the Modular Enrichment Activities Based on Gardner Multiple Intelligences and Sternberg Thinking Skills

This study aimed to test the effectiveness of the modular enrichment activities which were developed based on multiple intelligences and thinking skills. The adoption of the four types of intelligence as introduced by Gardner (1983) consisted of verbal linguistic, logical mathematical, visual and kinesthetic intelligences. While the analytical, practical and creative thinking skills as raised by Sternberg (1985) in the triarchic theory of intelligence (Sternberg Triarchic Theory). A quasi-experimental research design was used which involved academically-gifted students from two Mara Junior Science Colleges (MRSMs) in Malaysia. Two instruments were used in this study, the Sternberg Triarchic Ability Test (STAT) and multiple intelligence test. ANCOVA analysis and Kruskal-Wallis H test were then employed to analyze the data. The findings suggested that the integration of Gardner's multiple intelligence and Sternberg’s thinking skills through the modular enrichment activities stimulated the multiple intelligence profiles and the levels of the thinking skills of the treatment group significantly. Keywords : Multiple intelligences, Thinking skills, Enrichment activities