Miracle-dz/UniFAR-FTUs huggingface dataset:
Foley Catheter versus Vaginal Misoprostol for Labour Induction

Objectives. To compare the efficacy and safety of intravaginal misoprostol with transcervical Foley catheter for labour induction. Material and Methods. One hundred and four women with term gestation, with Bishop score < 4, and with various indications for labour induction were randomly divided into two groups. In Group I, 25 μg of misoprostol tablet was placed intravaginally, 4 hourly up to maximum 6 doses. In Group II, Foley catheter 16F was placed through the internal os of the cervix under aseptic condition and then inflated with 50 cc of sterile saline. Statistical analysis was done using SPSS software. Results. The induction to delivery interval was 14.03 ± 7.61 hours versus 18.40 ± 8.02 hours (p < 0.01). The rate of vaginal delivery was 76.7% versus 56.8% in misoprostol and transcervical Foley catheter group, respectively. Uterine hyperstimulation was more common with misoprostol. Neonatal outcome was similar in both the groups. Conclusion. Intravaginal misoprostol is associated with a shorter induction to delivery interval as compared to Foley's catheter and it increases the rate of vaginal delivery in cases of unripe cervix at term. Transcervical Foley catheter is associated with a lower incidence of uterine hyperstimulation during labour.
Becoming an HR strategic partner: tales of transition

This article aims to bridge the gap between previous examinations of HR strategic partnership from a role perspective and an emerging interest in the social construction of identity. I consider ‘strategic partner’ as a local, flexible social construction framed by the broader occupational context. Based on a year-long ethnographic study, I examine the experiences of HR practitioners ‘becoming’ strategic partners, considering the themes of becoming strategic, becoming a partner and remaining a generalist. Practitioners depict becoming strategic as a ‘release’ from previous constraints, with becoming a partner positioned as filling a gap created by clients' deficiencies in people management. Meanwhile, tensions develop as strategic partners attempt to retain a say in transactional issues. I reflect on the resulting practical issues while also considering the role of HR practitioners in, in the words of Helen Francis, ‘the dynamic and socially complex nature of HRM’.
The EM parametric image reconstruction algorithm

A gauge for measuring flatness by utilizing the interference of light is composed of a block having a reference or standard surface of a high flatness and surfaces intersecting the reference surface. Three supporting members are fixedly secured to said surfaces in an appropriate arrangement. Each of three pins which is anchored to respective supporting member has a pointed top portion jut beyond the reference surface. The object or specimen to be tested is rested on said top portions of the three pins to support the specimen with the tested surface extending substantially in parallel with said reference surfaces in opposing position.
PERSPECTIVE: SPONTANEOUS DELETERIOUS MUTATION

Mildly deleterious mutation has been invoked as a leading explanation for a diverse array of observations in evolutionary genetics and molecular evolution and is thought to be a significant risk of extinction for small populations. However, much of the empirical evidence for the deleterious‐mutation process derives from studies of Drosophila melanogaster, some of which have been called into question. We review a broad array of data that collectively support the hypothesis that deleterious mutations arise in flies at rate of about one per individual per generation, with the average mutation decreasing fitness by about only 2% in the heterozygous state. Empirical evidence from microbes, plants, and several other animal species provide further support for the idea that most mutations have only mildly deleterious effects on fitness, and several other species appear to have genomic mutation rates that are of the order of magnitude observed in Drosophila. However, there is mounting evidence that some organisms have genomic deleterious mutation rates that are substantially lower than one per individual per generation. These lower rates may be at least partially reconciled with the Drosophila data by taking into consideration the number of germline cell divisions per generation. To fully resolve the existing controversy over the properties of spontaneous mutations, a number of issues need to be clarified. These include the form of the distribution of mutational effects and the extent to which this is modified by the environmental and genetic background and the contribution of basic biological features such as generation length and genome size to interspecific differences in the genomic mutation rate. Once such information is available, it should be possible to make a refined statement about the long‐term impact of mutation on the genetic integrity of human populations subject to relaxed selection resulting from modern medical procedures.
Structured Learning from Heterogeneous Behavior for Social Identity Linkage

Social identity linkage across different social media platforms is of critical importance to business intelligence by gaining from social data a deeper understanding and more accurate profiling of users. In this paper, we propose a solution framework, HYDRA, which consists of three key steps: (I) we model heterogeneous behavior by long-term topical distribution analysis and multi-resolution temporal behavior matching against high noise and information missing, and the behavior similarity are described by multi-dimensional similarity vector for each user pair; (II) we build structure consistency models to maximize the structure and behavior consistency on users' core social structure across different platforms, thus the task of identity linkage can be performed on groups of users, which is beyond the individual level linkage in previous study; and (III) we propose a normalized-margin-based linkage function formulation, and learn the linkage function by multi-objective optimization where both supervised pair-wise linkage function learning and structure consistency maximization are conducted towards a unified Pareto optimal solution. The model is able to deal with drastic information missing, and avoid the curse-of-dimensionality in handling high dimensional sparse representation. Extensive experiments on 10 million users across seven popular social networks platforms demonstrate that HYDRA correctly identifies real user linkage across different platforms from massive noisy user behavior data records, and outperforms existing state-of-the-art approaches by at least 20 percent under different settings, and four times better in most settings.
Near-ultrasound communication for TV's 2nd screen services

In this paper, we propose a near-ultrasound chirp signal-based communication for the TV's 2nd screen services. While near-ultrasound (with under 20 kHz frequency) communication has been developed for various applications recently, none of the previous work provides a perfect solution for 2nd screen services between TVs and smart devices. This is due mainly to the following real world challenges. The embedded signal in TV contents should be successfully received in a typical TV-watching environment by (i) delivering information at least at 15 bps with significantly low volume to avoid human perception, (ii) despite the presence of ambient noise, e.g., a tick, a snap, or a knock. To fulfill (i), we design chirp quaternary orthogonal keying (QOK) symbols. Especially, we aim to minimize inter-symbol interference (ISI) effects by symbol design in order to completely eliminate guard intervals. To resolve (ii), we propose the novel J-shape detection algorithms for both frame synchronization and carrier sensing. The proposed modem achieves almost zero frame error rate on a smartphone 2.7 m away from the TV even with minimal receive sound pressure level of 35 dBSPL, i.e., the noise level in a very quiet room. Moreover, throughout experiments and log analysis of 2nd screen service deployed in a nation-wide TV broadcasting system, J-shape detection algorithms are proven to achieve highly resilient performance for both frame synchronization and carrier sensing compared to previous schemes.
The Neural and Cognitive Time Course of Theory of Mind

Neuroimaging and neuropsychological studies implicate both frontal and temporoparietal cortices when humans reason about the mental states of others. Here, we report an event-related potentials study of the time course of one such “theory of mind” ability: visual perspective taking. The findings suggest that posterior cortex, perhaps the temporoparietal cortex, calculates and represents the perspective of self versus other, and then, later, the right frontal cortex resolves conflict between perspectives during response selection.
Heat and Osmotic Stress Responses of Probiotic Lactobacillus rhamnosus HN001 (DR20) in Relation to Viability after Drying

ABSTRACT The viability of lactic acid bacteria in frozen, freeze-dried, and air-dried forms is of significant commercial interest to both the dairy and food industries. In this study we observed that when prestressed with either heat (50°C) or salt (0.6 M NaCl), Lactobacillus rhamnosus HN001 (also known as DR20) showed significant (P < 0.05) improvement in viability compared with the nonstressed control culture after storage at 30°C in the dried form. To investigate the mechanisms underlying this stress-related viability improvement in L. rhamnosus HN001, we analyzed protein synthesis in cultures subjected to different growth stages and stress conditions, using two-dimensional gel electrophoresis and N-terminal sequencing. Several proteins were up- or down-regulated after either heat or osmotic shock treatments. Eleven proteins were positively identified, including the classical heat shock proteins GroEL and DnaK and the glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase, lactate dehydrogenase, enolase, phosphoglycerate kinase, and triose phosphate isomerase, as well as tagatose 1,6-diphosphate aldolase of the tagatose pathway. The phosphocarrier protein HPr (histidine-containing proteins) was up-regulated in cultures after the log phase irrespective of the stress treatments used. The relative synthesis of an ABC transport-related protein was also up-regulated after shock treatments. Carbohydrate analysis of cytoplasmic contents showed higher levels (20 ± 3 μg/mg of protein) in cell extracts (CFEs) derived from osmotically stressed cells than in the unstressed control (15 ± 3 μg/mg of protein). Liquid chromatography of these crude carbohydrate extracts showed significantly different profiles. Electrospray mass spectrometry analysis of CFEs revealed, in addition to normal mono-, di-, tri-, and tetrasaccharides, the presence of saccharides modified with glycerol.
CRUSH: fast and scalable data reduction for imaging arrays

CRUSH is an approach to data analysis under noise interference, developed specifically for submillimeter imaging arrays. The method uses an iterated sequence of statistical estimators to separate source and noise signals. Its filtering properties are well-characterized and easily adjusted to preference. Implementations are well-suited for parallel processing and its computing requirements scale linearly with data size - rendering it an attractive approach for reducing the data volumes from future large arrays.
Using Historical In-Process and Product Metrics for Early Estimation of Software Failures

The benefits that a software organization obtains from estimates of product quality are dependent upon how early in the product cycle that these estimates are available. Early estimation of software quality can help organizations make informed decisions about corrective actions. To provide such early estimates we present an empirical case study of two large scale commercial operating systems, Windows XP and Windows Server 2003. In particular, we leverage various historical in-process and product metrics from Windows XP binaries to create statistical predictors to estimate the post-release failures/failure-proneness of Windows Server 2003 binaries. These models estimate the failures and failure-proneness of Windows Server 2003 binaries at statistically significant levels. Our study is unique in showing that historical predictors for a software product line can be useful, even at the very large scale of the Windows operating system
Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis

Summary Kallikrein-related peptidases, a subgroup of the serine protease enzyme family, are considered to be important prognostic biomarkers in cancer. In this study we sought to determine the prognostic value of kallikrein-related peptidase 8 (KLK8,hK8,KLK-8) in ovarian cancer using a novel method of compartmentalised in situ protein analysis. A tissue array composed of 150 advanced stage ovarian cancers, uniformly treated with surgical debulking followed by platinum-paclitaxel combination chemotherapy, was constructed. For the evaluation of kallikrein-related peptidase 8 protein expression, we used an immunofluorescence-based method of automated in situ quantitative protein analysis (AQUA). Mean follow-up time of the cohort was 34.35 months. One hundred twenty-six of 150 cases had sufficient tissue for AQUA analysis. There were significant correlations between tumour mask KLK8 protein expression levels and clinicopathological variables, including grade (p=0.0011), residual disease (p=0.0063) and clinical response to chemotherapy(p=0.0346). In univariate survival analysis there was a significant correlation between KLK8 tumour mask expression and five years progression-free survival, meanwhile it was not associated with five-year overall survival (p =0.0694). Specifically, low KLK8 expression correlated with better outcome (top vs. bottom quartile, p=0.0319). In multivariate survival analysis, adjusting for well-characterised prognostic variables, tumour KLK8 expression level retained its prognostic significance for progression-free survival (95%CI: 0.341–1.027, p=0.045). The possibility that KLK8 may be a suitable candidate as a diagnostic and prognostic marker warrants further investigation.
Angiotensin II suppresses osteoblastic differentiation and mineralized nodule formation via AT1 receptor in ROS17/2.8 cells

Introduction Angiotensin II (Ang II) not only regulates systemic blood pressure through a vasoconstrictive effect, but also promotes bone resorption. We recently reported that Ang II (10–6 M) stimulated the production of matrix metalloproteinases via the AT1 receptor in osteoblastic ROS17/2.8 cells, but suppressed alkaline phosphatase activity. However, the roles of Ang II in osteoblastic differentiation and the function of osteogenesis in osteoblasts are unclear. Therefore, we examined the effect of Ang II on the expression of osteogenesis-related transcription factors and extracellular matrix (ECM) proteins, as well as mineralized nodule formation in ROS17/2.8 cells. Material and methods ROS17/2.8 cells were cultured with 0 (control) or 10–6 M Ang II in the presence or absence of the AT1 receptor blocker losartan. Mineralized nodule formation was detected by Alizarin Red staining. Gene and protein expression levels of transcription factors and ECM proteins were determined using real-time PCR and Western blotting, respectively. Results Runx2, Msx2, and osteocalcin expression significantly decreased with Ang II compared to the control, whereas AJ18 expression significantly increased. Osterix, Dlx5, type I collagen, bone sialoprotein, and osteopontin expression was unaffected. Mineralized nodule formation and calcium content in mineralized nodules decreased with Ang II. Losartan blocked suppressive or stimulatory effects of Ang II on Runx2, Msx2, osteocalcin, and AJ18 expression. Conclusions These results suggest that Ang II suppresses osteoblastic differentiation by altering the expression of osteogenesis-related transcription factors via the AT1 receptor and the function of osteogenesis in ROS17/2.8 cells.
The Eclipsing Supersoft X-Ray Binary CAL 87

We present and discuss 25 spectra obtained in 1996 November, covering all phases of the CAL 87 binary system. These spectra are superior both in signal-to-noise ratio and wavelength coverage to previously published data, so additional spectral features can be measured. Photometry obtained on the same nights is used to confirm the ephemeris and for comparison with light curves from previous years. Analysis of the color variation through the orbital cycle has been carried out using archival MACHO data. When a barely resolved red field star is accounted for, there is no (V-R) color variation, even through eclipse. There have been substantial changes in the depth of minimum light since 1988; it has decreased more than 0.5 mag in the last several years. The spectral features and radial velocities are also found to vary not only through the 0.44 day orbit but also over timescales of a year or more. Possible interpretations of these long-term changes are discussed. The 1996 spectra contain phase-modulated Balmer absorption lines not previously seen, apparently arising in gas flowing from the region of the compact star. The changes in emission-line strengths with orbital phase indicate that there are azimuthal variations in the accretion disk structures. Radial velocities of several lines give different amplitudes and phasing, making determination of the stellar masses difficult. All solutions for the stellar masses indicate that the companion star is considerably less massive than the degenerate star. The Balmer absorption-line velocities correspond to masses of ~1.4 M☉ for the degenerate star and ~0.4 M☉ for the mass donor. However, the strong He II emission lines indicate a much more massive accreting star, with MX > 4 M☉.
The future of the psychological contract in a non-western context: The case of Bangladesh

This paper investigates the implications of psychological contract breach on employees’ retention and their individual performance in a non-western context where critical parameters such as employee loyalty to individual managers, high unemployment, unsatisfactory working conditions and absence of effective trade unions can present themselves as critical variable in our understanding of the psychological contract. The extant literature in the field of organisational psychology, and in relation to the psychological contract, has predominantly focused on adopting main effects approach in investigating the psychological contract-outcome relationships. In so doing various individual and situational variables were largely ignored (Agarwal and Bhargava, 2013). This paper attempts to fill some of the vacuum left in the field.
Absence of anti-Müllerian hormone (AMH) and M2A immunoreactivities in Sertoli cell-only syndrome and maturation arrest with and without AZF microdeletions.

BACKGROUND Some genes identified in the AZF locus are expressed only in germinal cells; others are ubiquitous. AZF microdeletions seem to occur at the earliest stages of ontogenetic development, and one might therefore assume that Sertoli cells preserve some immature characteristics and that their immunophenotype may be modified by the existence of a molecular defect. MATERIALS AND METHODS Two immunohistological markers of Sertoli cell immaturity [anti-Müllerian hormone (AMH) and M2A] were tested in two histopathological groups (maturation arrest at spermatocyte I stage and Sertoli cell-only syndrome). We analysed 68 testicular samples obtained from 39 patients with non-obstructive azoospermia associated or not with AZF microdeletions. RESULTS The absence of M2A and AMH immunoreactivity in adult gonads was observed without any correlation to spermatogenetic impairment or molecular deficit in the AZF region. In the samples of these two series, Sertoli cells showed a mature phenotype for AMH and M2A markers. CONCLUSIONS In patients with AZF microdeletions, the genotype-phenotype correlations seem to be more complex than has been suggested previously; more detailed characterization of the immunohistochemical phenotype associated with the molecular defect may be useful in understanding the spermatogenic failure mechanism.
Exploring the role of assistant educational psychologists within local authority educational psychology services in England

ABSTRACT Following consistently high demands for educational psychology services (EPSs) and recent influences upon the delivery of EPSs, the contribution of assistant educational psychologists (EPs) was explored via a multiple case study design. Participants included assistant psychologists, EPs and senior/principal psychologists from two local authority EPSs in England. Recorded focus groups and interviews were transcribed and a thematic analysis was conducted to produce a cross case analysis. It was found that the assistant EP role emerged from EP recruitment difficulties and that assistants work in diverse ways to enhance and extend the EPS offer to schools to improve outcomes for children; however, the role did not reduce EP workloads. Challenges to the successful deployment of assistant EPs were highlighted along with implications for their practice and future research. Benefits for the assistants themselves included career progression experience.
Wavelet Transform Based Algorithm for High-Impedance Faults Detection in Distribution Feeders

This paper presents a wavelet transform based technique for high-impedance faults detection in power distribution feeders. In this study, accurate electrical models for a HIF and capacitor switching event on a power network are developed and simulated using MATLAB. The analysis of the resulted fault signals, using the Discrete Wavelet Transform (DWT) yields single-phase current and voltage in the low frequency range, which are fed to a classifier for pattern recognition. The classifier algorithm in this paper is based on a moving window approach whereby the one-cycle window of the DWT output is moved continuously by one sample. The algorithm when tested with data obtained from various computer simulations carried out in this study, produced impressive results in HIF detection and discrimination. The major contribution of this work is that it is able to determine the magnitude of the fault current, which many earlier researchers did not consider in their works.
FPGA-Based Real-Time Motion Detection for Automated Video Surveillance Systems

Design of automated video surveillance systems is one of the exigent missions in computer vision community because of their ability to automatically select frames of interest in incoming video streams based on motion detection. This research paper focuses on the real-time hardware implementation of a motion detection algorithm for such vision based automated surveillance systems. A dedicated VLSI architecture has been proposed and designed for clustering-based motion detection scheme. The working prototype of a complete standalone automated video surveillance system, including input camera interface, designed motion detection VLSI architecture, and output display interface, with real-time relevant motion detection capabilities, has been implemented on Xilinx ML510 (Virtex-5 FX130T) FPGA platform. The prototyped system robustly detects the relevant motion in real-time in live PAL (720 × 576) resolution video streams directly coming from the camera.