Miracle-dz/UniFAR-FTUs huggingface dataset:
Self-Organized Public-Key Management for Mobile Ad Hoc Networks

In contrast with conventional networks, mobile ad hoc networks usually do not provide online access to trusted authorities or to centralized servers, and they exhibit frequent partitioning due to link and node failures and to node mobility. For these reasons, traditional security solutions that require online trusted authorities or certificate repositories are not well-suited for securing ad hoc networks. We propose a fully self-organized public-key management system that allows users to generate their public-private key pairs, to issue certificates, and to perform authentication regardless of the network partitions and without any centralized services. Furthermore, our approach does not require any trusted authority, not even in the system initialization phase.
A First-Order Stochastic Primal-Dual Algorithm with Correction Step

ABSTRACT In this article, we investigate the convergence properties of a stochastic primal-dual splitting algorithm for solving structured monotone inclusions involving the sum of a cocoercive operator and a composite monotone operator. The proposed method is the stochastic extension to monotone inclusions of a proximal method studied in the literature for saddle point problems. It consists in a forward step determined by the stochastic evaluation of the cocoercive operator, a backward step in the dual variables involving the resolvent of the monotone operator, and an additional forward step using the stochastic evaluation of the cocoercive operator introduced in the first step. We prove weak almost sure convergence of the iterates by showing that the primal-dual sequence generated by the method is stochastic quasi-Fejér-monotone with respect to the set of zeros of the considered primal and dual inclusions. Additional results on ergodic convergence in expectation are considered for the special case of saddle point models.
Prevalence of Benign Prostatic Hyperplasia on Jeju Island: Analysis from a Cross-sectional Community-based Survey

Purpose We report on the prevalence of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among men of Jeju Island, representing a coastal and insular area, using a cross-sectional community-based survey. Materials and Methods A total of 553 participants in a prostate health screening campaign on Jeju Island were subjected to measurements of the International Prostate Symptom Score (IPSS), prostate volume, uroflowmetry, postvoiding residual urine volume, and prostate-specific antigen levels. Eliminating 58 participants who were suspected of having prostate cancer, we analyzed the data from 495 participants. The definition of BPH was a combination of moderate IPSS (8~19) to severe IPSS (>19) and prostate enlargement (>30 g on transrectal ultrasonography). Results The prevalence of BPH was 21.0% overall: 11.6% among subjects aged 50~59 years, 18.1% for those aged 60~69, 30.8% for those aged 70~79 and 50.8% among those aged 80 years or more. Compared with previous studies in urban or rural areas, the prevalence was slightly lower. The prevalence of BPH and of moderate to severe LUTS increased with age and showed significant differences between age groups (p=0.028 and 0.033, respectively). A positive correlation was found between the IPSS and quality of life score. Among subunits of IPSS, the nocturia score contributed most to the severity of LUTS and had the highest correlation with a quality of life score. Conclusions The overall prevalence of BPH in this study was 21.0%, which is slightly lower than in previous studies in urban or rural areas.
Novel Targeting Signals Mediate the Sorting of Different Isoforms of the Tail-Anchored Membrane Protein Cytochrome b5 to Either Endoplasmic Reticulum or Mitochondria

Tail-anchored membrane proteins are a class of proteins that are targeted posttranslationally to various organelles and integrated by a single segment of hydrophobic amino acids located near the C terminus. Although the localization of tail-anchored proteins in specific subcellular compartments in plant cells is essential for their biological function, the molecular targeting signals responsible for sorting these proteins are not well defined. Here, we describe the biogenesis of four closely related tung (Aleurites fordii) cytochrome b5 isoforms (Cb5-A, -B, -C, and -D), which are small tail-anchored proteins that play an essential role in many cellular processes, including lipid biosynthesis. Using a combination of in vivo and in vitro assays, we show that Cb5-A, -B, and -C are targeted exclusively to the endoplasmic reticulum (ER), whereas Cb5-D is targeted specifically to mitochondrial outer membranes. Comprehensive mutational analyses of ER and mitochondrial Cb5s revealed that their C termini, including transmembrane domains (TMD) and tail regions, contained several unique physicochemical and sequence-specific characteristics that defined organelle-specific targeting motifs. Mitochondrial targeting of Cb5 was mediated by a combination of hydrophilic amino acids along one face of the TMD, an enrichment of branched β-carbon–containing residues in the medial portion of the TMD, and a dibasic -R-R/K/H-x motif in the C-terminal tail. By contrast, ER targeting of Cb5 depended primarily upon the overall length and hydrophobicity of the TMD, although an -R/H-x-Y/F- motif in the tail was also a targeting determinant. Collectively, the results presented provide significant insight into the early biogenetic events required for entry of tail-anchored proteins into either the ER or mitochondrial targeting pathways.
Bmc Medical Informatics and Decision Making Variation in the Psychosocial Determinants of the Intention to Prescribe Hormone Therapy Prior to the Release of the Women's Health Initiative Trial: a Survey of General Practitioners and Gynaecologists in France and Quebec

Background: Theory-based approaches are advocated to improve our understanding of prescription behaviour. This study is an application of the theory of planned behaviour (TPB) with additional variables. It was designed to assess which variables were associated with the intention to prescribe hormone therapy (HT). In addition, variations in the measures across medical specialities (GPs and gynaecologists) and across countries (France and Quebec) were investigated.
Stuck in Mobility? Interrupted Journeys of Migrants With Precarious Legal Status in Europe

Abstract Due to lack of access to work and support services migrants with precarious legal status engage in onward mobility within EUrope and thus contest the migration regime that aims to control and limit their mobility. This article highlights the ambiguous nature of mobility from a critical mobilities perspective based on multi-sited ethnographic research and interviews with migrants in Austria, Germany, Italy, and Switzerland. By focusing on their interrupted journeys, the article shows how migrants use mobility to secure basic needs and avoid migration control attempts and how this enhanced mobility aggravates emotional instability.
An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense in Arabidopsis[C][W]

The Arabidopsis thaliana resistance gene RPW8 triggers the hypersensitive response (HR) to restrict powdery mildew infection via the salicylic acid–dependent signaling pathway. To further understand how RPW8 signaling is regulated, we have conducted a genetic screen to identify mutations enhancing RPW8-mediated HR-like cell death (designated erh). Here, we report the isolation and characterization of the Arabidopsis erh1 mutant, in which the At2g37940 locus is knocked out by a T-DNA insertion. Loss of function of ERH1 results in salicylic acid accumulation, enhanced transcription of RPW8 and RPW8-dependent spontaneous HR-like cell death in leaf tissues, and reduction in plant stature. Sequence analysis suggests that ERH1 may encode the long-sought Arabidopsis functional homolog of yeast and protozoan inositolphosphorylceramide synthase (IPCS), which converts ceramide to inositolphosphorylceramide. Indeed, ERH1 is able to rescue the yeast aur1 mutant, which lacks the IPCS, and the erh1 mutant plants display reduced (∼53% of wild type) levels of leaf IPCS activity, indicating that ERH1 encodes a plant IPCS. Consistent with its biochemical function, the erh1 mutation causes ceramide accumulation in plants expressing RPW8. These data reinforce the concept that sphingolipid metabolism (specifically, ceramide accumulation) plays an important role in modulating plant programmed cell death associated with defense.
Development of Youtube integrated google classroom based e-learning media for the light-weight vehicle engineering vocational high school

The purpose of this research is to produce the e-learning media for the Light-Weight Vehicle Chassis and Powertrain Maintenance Subject. The type of this research is the research and development. The procedure applied in this research is the ADDIE model. Construct testing by the expert is done by curriculum expert, practitioner and teaching media expert. Construct testing and content testing were also conducted to 23 students as the user. Qualitative data were analyzed using an iterative step that is reading/memoing, describing, and classifying. Quantitative data were analyzed with descriptive statistics. The research result shows that YouTube Integrated Google Classroom Based E-Learning Media has been produced and tested for Light-Weight Vehicle Chassis and Powertrain Maintenance subjects. The construct testing shows that this e-learning media is decent based on an expert's judgment, and based on the user response shows that the reliability of the construct is good. The content testing shows that students who use the YouTube Integrated Google Classroom Based E-Learning Media have significantly greater learning outcomes compared with students who use the internet to access the website without control.
How Burnout Affects Turnover Intention? The Conditional Effects of Subjective Vitality and Supervisor Support

Although numerous researchers in the literature have tried to show that low levels of supervisory support contributing to job burnout and turnover, the moderating effects of supervisor support and subjective vitality on this interaction still keep unclarified. This paper examines the effect of burnout on turnover intention of 295 employees, who are employed in Turkish health sector. It is also aimed whether supervisor support and subjective vitality have moderating effects on job burnout-turnover intention relationship. The findings show that the two dimensions of burnout namely emotional exhaustion and depersonalization positively affects turnover intention. Moreover, the moderating effects of supervisor support and subjective vitality on the relationship between burnout (emotional exhaustion and depersonalization) and turnover intention are statistically significant. Specifically, the levels of subjective vitality and supervisor support increases, the burnoutturnover intention relationship gradually strengthens. Managerial applications and further research directions are provided.
The effect of Dictogloss Technique on the students’ writing skill

Dictogloss can be considered as way for integrating form and meaning in the learning context. The main objective of this research is to analyze whether: (1) Dictogloss is more effective than Direct Instruction to teach writing for the eleventh grades students, and (2) students having high motivation have better writing skill than those having low motivation for the eleventh-grade students. This article refers to an experimental study on the effectiveness of Dictogloss to teach writing skill at one of Islamic School in Surakarta, Indonesia. The sampling used in this research was cluster random sampling with two classes as sample, namely the experimental class taught using Dictogloss and the control class taught using Direct Instruction. To collect the data, there were two instruments used in this research namely, the writing test and the motivation questionnaire. After treatment was given to both classes in eight meetings, a post-test of writing to obtain data was conducted. The data were analyzed by using 2x2 Multifactor Analysis of Variance (ANOVA). Before conducting the ANOVA test, pre-requisite test namely normality and homogeneity test were conducted. The result of this research shows that: (1) Dictogloss is more effective than Direct Instruction to teach writing, and (2) students having high motivation have better writing skill than those having low motivation. Therefore, it is recommended for the English teacher to apply Dictogloss in writing activity to promote an effective teaching on writing skill. In conclusion, Dictogloss can be used to improve students’ writing skill for the eleventh-grade students.
Levels of indoxyl sulfate are associated with severity of coronary atherosclerosis.

PURPOSE Indoxyl sulfate (IS) is linked to endothelial damage, NF-κB activation and induced development of atherosclerosis. The purpose of this study was to investigate the relationship between serum IS levels and the severity of coronary artery stenosis. In addition, the relationship among IS and various cardiovascular risk factors was also explored. METHODS Serum IS concentrations were measured using ultra performance liquid chromatography in 191 consecutive patients presenting with stable angina. The associations between serum IS levels and angiographic indexes of the number of diseased vessels, modified Gensini scores and calcium scores were determined. RESULTS Patients with significant coronary artery stenosis were found to have higher serum IS levels than patients with normal coronary arteries. Using multivariate analysis, serum IS levels were found to be independently associated with the presence and severity of coronary artery disease (CAD). Furthermore, statistically significant correlation was observed between the serum IS levels and age, Agatston calcium score, volume calcium score, modified Gensini score, coronary lesions, coronary disease and Framingham-10 year risk score. CONCLUSION This study indicates that serum IS levels are significantly higher in the presence of CAD and correlate with the severity of the disease and coronary atherosclerosis scores, which suggest that increased serum IS may be involved in the pathogenesis of coronary atherosclerosis.
Niche Modeling of Dengue Fever Using Remotely Sensed Environmental Factors and Boosted Regression Trees

Dengue fever (DF), a vector-borne flavivirus, is endemic to the tropical countries of the world with nearly 400 million people becoming infected each year and roughly one-third of the world’s population living in areas of risk. The main vector for DF is the Aedes aegypti mosquito, which is also the same vector of yellow fever, chikungunya, and Zika viruses. To gain an understanding of the spatial aspects that can affect the epidemiological processes across the disease’s geographical range, and the spatial interactions involved, we created and compared Bernoulli and Poisson family Boosted Regression Tree (BRT) models to quantify the overall annual risk of DF incidence by municipality, using the Magdalena River watershed of Colombia as a study site during the time period between 2012 and 2014. A wide range of environmental conditions make this site ideal to develop models that, with minor adjustments, could be applied in many other geographical areas. Our results show that these BRT methods can be successfully used to identify areas at risk and presents great potential for implementation in surveillance programs.
The impact of mindfulness training on reflective thinking and attitudes towards patients in dementia care

Background The current pilot study investigated the impact o f an eight-week m indfulness intervention on reflective practice and attitudes to dementia among NHS staff using a m ixed m ethods approach. A growing body o f research evidence suggests that m indfulness training is an effective stress m anagem ent intervention for health professionals (Irving et al., 2009)and m ay impact beneficially on direct client outcom es (Singh et al.,2006). Other comm entators hypothesise that m indfulness intervention could prom ote reflective m odes o f clinical thinking (e.g. Epstein 1999; 2003, Connelly 2005). This pilot study aimed to assess the effect o f mindfulness training on measures o f reflection and person centred attitudes to care among healthcare workers with a high degree o f clinical contact with people with dementia. Method Following the granting o f ethics perm ission from the local NFIS trust, staff participants were recruited via posters, email, team presentations and mindfulness ‘taster’ workshops. Three consecutive eight week intervention groups were facilitated by the investigator at 3 hospital sites where 25 participants attended initial sessions. A total o f 18 participants completed the intervention and outcome data was collected using a m ixed m ethods approach. Focus group data was analysed according to a thematic analysis based on the constructivist version o f grounded theory (Charmaz 1995). M ain outcome measures were the Groningham Reflective Abilities Scale (GRAS) (Aukes et al., 2007) and Approaches to Dem entia Questionnaire (ADQ) (Lintem, 2000), which were collected in w eek one, w eek eight and at one m onth’s follow-up after the intervention. Background measures o f the Kentucky Inventory o f M indfulness Skills (KIMS) (Baer et al., 2004) and M aslach Burnout Inventory (MBI) were also collected to see whether these variables influenced performance. Results The overriding them e that emerged from grounded theory analysis was that mindfulness practice stim ulated an awareness o f and some reflection on personal
Gravitational Collapse in Turbulent Molecular Clouds. I. Gasdynamical Turbulence

Observed molecular clouds often appear to have very low star formation efficiencies and lifetimes an order of magnitude longer than their free-fall times. Their support is attributed to the random supersonic motions observed in them. We study the support of molecular clouds against gravitational collapse by supersonic, gasdynamical turbulence using direct numerical simulation. Computations with two different algorithms are compared: a particle-based, Lagrangian method (smoothed particle hydrodynamics [SPH]) and a grid-based, Eulerian, second-order method (ZEUS). The effects of both algorithm and resolution can be studied with this method. We find that, under typical molecular cloud conditions, global collapse can indeed be prevented, but density enhancements caused by strong shocks nevertheless become gravitationally unstable and collapse into dense cores and, presumably, stars. The occurrence and efficiency of local collapse decreases as the driving wavelength decreases and the driving strength increases. It appears that local collapse can be prevented entirely only with unrealistically short wavelength driving, but observed core formation rates can be reproduced with more realistic driving. At high collapse rates, cores are formed on short timescales in coherent structures with high efficiency, while at low collapse rates they are scattered randomly throughout the region and exhibit considerable age spread. We suggest that this naturally explains the observed distinction between isolated and clustered star formation.
Shuttle Vector Expression in Thermococcus kodakaraensis: Contributions of cis Elements to Protein Synthesis in a Hyperthermophilic Archaeon

ABSTRACT Shuttle vectors that replicate stably and express selectable phenotypes in both Thermococcus kodakaraensis and Escherichia coli have been constructed. Plasmid pTN1 from Thermococcus nautilis was ligated to the commercial vector pCR2.1-TOPO, and selectable markers were added so that T. kodakaraensis transformants could be selected by ΔtrpE complementation and/or mevinolin resistance. Based on Western blot measurements, shuttle vector expression of RpoL-HA, a hemagglutinin (HA) epitope-tagged subunit of T. kodakaraensis RNA polymerase (RNAP), was ∼8-fold higher than chromosome expression. An idealized ribosome binding sequence (5′-AGGTGG) was incorporated for RpoL-HA expression, and changes to this sequence reduced expression. Changing the translation initiation codon from AUG to GUG did not reduce RpoL-HA expression, but replacing AUG with UUG dramatically reduced RpoL-HA synthesis. When functioning as translation initiation codons, AUG, GUG, and UUG all directed the incorporation of methionine as the N-terminal residue of RpoL-HA synthesized in T. kodakaraensis. Affinity purification confirmed that an HA- plus six-histidine-tagged RpoL subunit (RpoL-HA-his6) synthesized ectopically from a shuttle vector was assembled in vivo into RNAP holoenzymes that were active and could be purified directly from T. kodakaraensis cell lysates by Ni2+ binding and imidazole elution.
Virtual Channels in Networks on Chip: Implementation and Evaluation on Hermes NoC

Networks on chip (NoCs) draw on concepts inherited from distributed systems and computer networks subject areas to interconnect IP cores in a structured and scalable way. Congestion in NoCs reduces the overall system performance. This effect is particularly strong in networks where a single buffer is associated with each input channel, which simplifies router design, but prevents packets from sharing a physical channel at any given instant of time. The goal of this work is to describe the implementation of a mechanism to reduce performance penalization due to packet concurrence for network resources in NoCs. One way to reduce congestion is to multiplex a physical channel using virtual channels (VCs). VCs reduce latency and increase network throughput. The insertion of VCs also enables to implement policies for allocating the physical channel bandwidth, which enables to support quality of service (QoS) in applications. This paper has two main contributions. The first is the detailed implementation of a NoC router with a parameterizable number of VCs. The second is the evaluation of latency and throughput in reasonably sized instances of the Hermes NoC (8 times 8 mesh), with and without VCs. Additionally, the paper compares the features of the proposed router with others employing VCs. Results show that NoCs with VCs accept higher injections rates w.r. t. NoCs without VCs, with a small standard deviation in the latency values, guaranteeing precise packet latency estimation
Let me tell you a story: Narrative effects in the communication of stigma toward migrant workers in China

ABSTRACT This study investigated the impact of narratives on urban dwellers’ attitudes toward migrant workers in China. With a 2 (message valence: positive or negative)2 (message type: narrative or description) between-subjects factorial design, 261 participants were randomly assigned to conditions to assess their emotional reactions and stigma toward migrant workers. The results showed that positive messages elicited less negative emotion and stigma compared to negative messages. The effects of message type on stigma differed by message valence. Compared to descriptions, narratives directly reduced stigma in positive conditions, while the relationship in negative conditions was mediated by perceived message believability.