Miracle-dz/UniFAR-FTUs huggingface dataset:
Overexpression of a Modified Plant Thionin Enhances Disease Resistance to Citrus Canker and Huanglongbing (HLB)

Huanglongbing (HLB or citrus greening disease) caused by Candidatus Liberibacter asiaticus (Las) is a great threat to the US citrus industry. There are no proven strategies to eliminate HLB disease and no cultivar has been identified with strong HLB resistance. Citrus canker is also an economically important disease associated with a bacterial pathogen (Xanthomonas citri). In this study, we characterized endogenous citrus thionins and investigated their expression in different citrus tissues. Since no HLB-resistant citrus cultivars have been identified, we attempted to develop citrus resistant to both HLB and citrus canker through overexpression of a modified plant thionin. To improve effectiveness for disease resistance, we modified and synthesized the sequence encoding a plant thionin and cloned into the binary vector pBinPlus/ARS. The construct was then introduced into Agrobacterium strain EHA105 for citrus transformation. Transgenic Carrizo plants expressing the modified plant thionin were generated by Agrobacterium-mediated transformation. Successful transformation and transgene gene expression was confirmed by molecular analysis. Transgenic Carrizo plants expressing the modified thionin gene were challenged with X. citri 3213 at a range of concentrations, and a significant reduction in canker symptoms and a decrease in bacterial growth were demonstrated compared to nontransgenic plants. Furthermore, the transgenic citrus plants were challenged with HLB via graft inoculation. Our results showed significant Las titer reduction in roots of transgenic Carrizo compared with control plants and reduced scion Las titer 12 months after graft inoculation. These data provide promise for engineering citrus disease resistance against HLB and canker.
Role of macula densa in diuretics-induced renin release.

Diuretic therapy may enhance renin release by various mechanisms, principally contraction of extracellular fluid volume and its effects, including a fall in arterial pressure. Awake hydropenic or volume-expanded rats received diuretics (amiloride and hydrochlorothiazide) that are known inhibitors of NaCl transport beyond the macula densa; also the well-known Na(+)-K(+)-2 Cl- transport system inhibitor furosemide was administered. We also evaluated the effect of a dose of ethacrynic acid (a drug that shares the same mechanism of action as furosemide but is not diuretic in the rat). The direct action of the diuretics on renin-producing cells was examined in isolated glomeruli; a rise in renin release was observed with the calmodulin inhibitor trifluoperazine (10(-5) M). Renin release in intact hydropenic rats was not altered by diuretic therapy, but furosemide increased plasma renin activity in hydropenic as well as in volume-expanded rats. This demonstrates the importance of furosemide inhibition of transport in the macula densa for its renin secretory action. None of the diuretics (amiloride, hydrochlorothiazide, ethacrynic acid, or furosemide) elicited changes in renin release from glomeruli (10(-6) to 10(-3) M); amiloride and hydrochlorothiazide (10(-4) to 10(-3) M) did not change renin release from slices, but 10(-3) M ethacrynic acid and furosemide increased renin secretion in this preparation. This suggests that an effect on the macula densa is essential in loop diuretic-mediated renin release. (ABSTRACT TRUNCATED AT 250 WORDS)
Evaluating Organized Breast Cancer Screening Implementation

The objective of our study was to evaluate organized breast cancer screening implementation by measuring the association between screening program enrollment and late-stage disease. Our setting was a health plan using mailed mammography reminders to women ages ≥40. We conducted yearly cross-sectional summaries of mammography experience and late-stage (regional or distant Surveillance Epidemiology and End Results Reporting (SEER) stage) breast cancer occurrence for all of the health-plan women ages ≥40 (1986–1998). We estimated the odds of late-stage breast cancer among health-plan and surrounding community women because it was too early to compare changes in mortality. We also estimated the odds of late-stage disease (1995–1998) associated with program enrollment and mammography screening among health-plan women. We found that mammography-within-two-years increased within the health plan from 25.9% to 51.2% among women ages 40–49 and from 32.9% to 74.7% among women ages ≥50. Health-plan late-stage rates were lower than those in the surrounding community [ages 40–49: odds ratio (OR), 0.87; 95% confidence interval (CI), 0.77–0.99; ages 50–79: OR, 0.86; 95% CI, 0.80–0.92] and declined parallel to the community. Among health-plan cancer cases, women ages ≥43 who were enrolled in the screening program and who had at least one program mammogram were less likely to have late-stage disease compared with the women not enrolled in the program (OR, 0.31; 95% CI, 0.16–0.61) but the odds of late-stage was also reduced among program-enrolled women not receiving program mammograms (OR, 0.45; 95% CI, 0.21–0.95). We concluded that enrollment in organized screening is associated with increased likelihood of mammography and reduced odds of late-stage breast cancer. Addressing the concerns of un-enrolled women and those without mammograms offers an opportunity for further late-stage disease reduction.
Heat Transfer and Friction Characteristics of the Microfluidic Heat Sink with Variously-Shaped Ribs for Chip Cooling

This paper experimentally and numerically investigated the heat transfer and friction characteristics of microfluidic heat sinks with variously-shaped micro-ribs, i.e., rectangular, triangular and semicircular ribs. The micro-ribs were fabricated on the sidewalls of microfluidic channels by a surface-micromachining micro-electro-mechanical system (MEMS) process and used as turbulators to improve the heat transfer rate of the microfluidic heat sink. The results indicate that the utilizing of micro-ribs provides a better heat transfer rate, but also increases the pressure drop penalty for microchannels. Furthermore, the heat transfer and friction characteristics of the microchannels are strongly affected by the rib shape. In comparison, the triangular ribbed microchannel possesses the highest Nusselt number and friction factor among the three rib types.
CLASSICAL LICHEN PLANUS AND LICHEN PLANUS PIGMENTOSUS INVERSUS OVERLAP WITH DERMOSCOPIC FEATURES

A 35-year-old man was referred to our hospital with a 3 months history of itchy cutaneous eruption on the trunk and asymptomatic cutaneous eruption on both groins. Physical examination revealed several, purplish-brown, scaly papules on the trunk and well-circumscribed, brown patchs in a linear distribution, on the bilateral inguinal regions. Dermoscopic examination of papules on the trunk revealed white crossing lines surrounded by brown dots; dermoscopic examination of patchs on groins revealed gray-brown dots and globules. According to histological, dermoscopical and clinical changes, the diagnoses of classical lichen planus (LP) for the lesions on the trunk; and lichen planus pigmentosus inversus (LPPI) for the lesions on the inguinal regions were made. Inhere we have described a rare case of LPPI and classical LP with dermoscopic features; and we suggest that LPPI is a variant of classical LP.
The influence of emotional intelligence and creativity on work performance and commitment

The employment customs is stirring drastically on an ordinary basis as the organization and employees’. In increasing of technological transform, competition and globalization continues perhaps with increasing employees’ work commitment and work performance. According to Turner, Barling and Zacharatos (2002), at present employees have to be allied to their work physically, emotionally and mentally in order to deliver stupendous performance. Lately many of organizations suffer because of low employee morality and productivity. As a result, operational costs increase and the quality of the outcome also affected. Poor emotional intelligence may slow down the employees’ performance. As a result employees are not motivated to work hard, besides that they do not have the ability to manage their emotions. Managers who supposing to monitors and manages the staff in most organizations are very slow in giving feedbacks and stimulate employees. Addition to, they were also facing difficulty in designation of works in order to enhance their employees’ work commitment and improve their performance. Employee can develop his or her emotional intelligence skills throughout their life. Employee and manager can improve their own emotional intelligence skills by learning the accurate methods to reduce stress. On the other hand, creativity can expand their capability to think, to produce new ideas, to make changes in organization which can influence their attitude to work hard and to increase their commitment through organization. The creativity of employees is very important to improve organizations if organizations are competing to achievement in today’s globally aggressive milieu. Creative manager and employee can assist their companies to overcome rigid and traditional problem solving approaches. This study seeks to examine the relationship between emotional intelligence and creativity on employees’ work commitment and work performance. This paper will contribute to the body of knowledge by filling the gap of the literature and will appear as a reference for those who help in the initiating process.
Informational needs of recently diagnosed cancer patients: A theoretical framework. Part I

This paper presents a theoretical framework that could specify the theoretical underpinnings of the informational needs concept. This framwork is derived from the theoretical and clinical literature, and it is examined in relation to previous research findings pertinent to informational needs of recently diagnosed cancer patients. The framwork identifies the nature, relevance, and scope of informational needs, as well as the person- and situation-related variables that may affect them. It is presented as a necessary background to the development of the method of measurement of informational needs and to the findings pertaining to the description of informational needs that will be presented in Part II of the paper.
Mechanical comparison of 3.5 mm broad dynamic compression plate, broad limited-contact dynamic compression plate, and narrow locking compression plate systems using interfragmentary gap models.

OBJECTIVES To compare (1) pullout properties between 3.5 mm cortical and locking screws, and (2) mechanical properties and gap displacements between the 3.5 mm broad limited-contact dynamic compression plate (LC-DCP), broad dynamic compression plate (DCP), and narrow locking compression plate (LCP), during axial loading of plate-stabilized diaphyseal fragments with an interfragmentary gap. STUDY DESIGN In vitro mechanical testing of implanted polyurethane foam (PUF) hollow cylinders that simulated compact or osteopenic diaphyseal bone. SAMPLE POPULATION (1) Five cortical and locking screws and (2) 4 PUF-plate constructs for each plate type; using high- and low-density (0.8 and 0.32 g/cm(3)) cylinders. METHODS (1) Screws were completely extracted at 5 mm/min. (2) Plated constructs were axially compressed at 300 N/s for 10 cycles from 5 to 355 N to determine gap displacement during physiologic loading, followed by single cycle increasing load to failure. RESULTS Pullout properties were not different between screw types. All plate constructs had yield loads over 3 times trotting loads. Gap closure occurred with LC-DCP and DCP constructs, but not LCP constructs. LCP construct properties were most similar to LC-DCP and DCP construct properties in the low-density model. CONCLUSION All plate systems sustained physiologic limb loads. Only LCP constructs maintained some gap integrity, although LC-DCP and DCP screws were placed in neutral position. CLINICAL RELEVANCE The LCP system is more likely than LC-DCP and DCP systems, with neutrally positioned screws, to maintain a planned interfragmentary gap, although gap strains range from 0% to 15% across the 2 mm gap during a trot load.
A New Class of Unsafe Primes

In this paper, a new special-purpose factorization algorithm is presented, which finds a prime factor p of an integer n in polynomial time, if 4p− 1 has the form db2 where d ∈ {3, 11, 19, 43, 67, 163} and b is an integer. Hence such primes should be avoided when we select the RSA secret keys. Some generalizations of the algorithm are discussed in the paper as well.
Scaling ultraviolet outflows in Seyferts

X-ray and UV absorbing outflows are frequently seen in AGN and have been cited as a possible feedback mechanism. Whether or not they can provide adequate feedback depends on how massive they are and how much energy they carry, but it depends in a more fundamental way upon whether they escape the potential of the black hole. If the outflows have reached their asymptotic velocity when we observe them, then all of these properties critically depend on the radius of the outflow: a value which is difficult to measure. The tightest limit on the distance of an X-ray warm absorber from the ionizing source is that of Krongold et al. (2007) for NGC 4051. We use NGC 4051 to model other observed UV outflows, and find that on the whole they may not provide meaningful feedback. The outflow velocities are below or just above the escape velocity of the black hole. This may be because they are not yet fully accelerated, or the duty cycle of high-velocity outflows may be small. Another possibility is that they may only provide meaningful feedback in higher-luminosity AGN, as we find a weak correlation between the ratio of outflow velocity to escape velocity and AGN continuum luminosity.
Frank Baker Memorial Scholarship Award Essays Genetic Evaluation of Carcass Traits : Looking at the Effects of Slaughter End Points

An exhaustive review of estimates of heritability (h) for a broad spectrum of beef production traits published in the scientific literature from 1945 to 1991 was conducted by Koots et al. (1994), but their review did not include other important carcass traits (e.g., kidney, pelvic, and heart fat percentage, yield grade, fat weight) and due to the purpose of their study, individual estimates of h for the traits reviewed were not reported, but only the weighted and unweighted averages. On the other hand, the review by Marshall (1994) reported estimates of h for some additional carcass traits, but only for cattle reared under U.S. conditions and, basically, estimates presented were on an age-constant basis. In addition, due to few estimates for the additional traits at that time, averages of estimates of h for several carcass traits were based on only one to three observations. Neither of the two reviews focused on the effect of end point on estimates of h. In the last ten years, as a consequence of the increased interest of many beef producers on carcass yield and quality to satisfy consumer demand, numerous studies of carcass traits have published estimates of h and genetic correlations (rg), doubling, at least, the number of estimates for many carcass traits. This review was conducted to present estimates of h and rg for carcass traits published in the scientific literature from 1962 to 2004. Because animals are slaughtered at, or carcass traits are adjusted to, different end points, the effects of adjusting for age, weight or fat depth on such estimates are also discussed.
Using Utility to Provision Storage Systems

Provisioning a storage system requires balancing the costs of the solution with the benefits that the solution will provide. Previous provisioning approaches have started with a fixed set of requirements and the goal of automatically finding minimum cost solutions to meet them. Such approaches neglect the cost-benefit analysis of the purchasing decision. Purchasing a storage system involves an extensive set of trade-offs between metrics such as purchase cost, performance, reliability, availability, power, etc. Increases in one metric have consequences for others, and failing to account for these trade-offs can lead to a poor return on the storage investment. Using a collection of storage acquisition and provisioning scenarios, we show that utility functions enable this cost-benefit structure to be conveyed to an automated provisioning tool, enabling the tool to make appropriate trade-offs between different system metrics including performance, data protection, and purchase cost.
THRESHOLD LAWS FOR THE BREAKUP OF ATOMIC PARTICLES INTO SEVERAL CHARGED FRAGMENTS

Processes with three or more charged particles in the final state exhibit a particular threshold behavior, as inferred by the famous Wannier law for a ($2e+$ion) system. We formulate a general solution which determines the threshold behavior of the cross section for multiple fragmentation. Applications to several systems of particular importance with three, four, and five leptons (electrons and positrons) in the field of a charged core, and two pairs of identical particles with opposite charges, are presented. Threshold exponents for these systems are predicted, while some previously suggested threshold laws are revised.
Influence of Lanthanum Doping on the Structural and Optical Properties of Hematite Nanopowders

Rare-earth elements are an attractive class of dopant elements, as they give easily trivalent cations that possibly altering the structure and other properties of the parent nanoparticles and creating multifunctional materials because of their f-electronic configurations. Herein, experimental evidence has been given for a better understanding of the factors that dictate the interactions of La doping on the structure and optical properties of iron oxide nanoparticles. For that, lanthanum doped hematite (α-Fe2O3) nanoparticles were prepared by a facile solution method using iron (III) chloride (FeCl3) as starting precursor and sodium hydroxide (NaOH) as reducing agent without templates at low temperature. As-prepared powders were subsequently calcined in air for 3 hr at 800 oC. Xray diffraction (XRD) technique was used to study the nanocrystal formation of α-Fe2O3 and Fourier Transform Raman (FT-Raman) spectral information identified the chemical bond structure of the nanoparticles. Morphology study of the nanoparticles was identified using Scanning Electron Microscope (SEM) and the incorporated La content was recognized from the Energy Dispersive X-ray Spectroscopy (EDS) analysis. The optical absorption spectrum was recorded in the wavelength range of 200-2000 nm and the optical parameters such as absorption coefficient and optical band gap energy of pure and doped Fe2O3 nanoparticles were determined. Obtained results are interpreted by considering the impregnation of trivalent La cations that replaced Fe cations of the host structure.
Learning about objects with human teachers

A general learning task for a robot in a new environment is to learn about objects and what actions/effects they afford. To approach this, we look at ways that a human partner can intuitively help the robot learn, Socially Guided Machine Learning. We present experiments conducted with our robot, Junior, and make six observations characterizing how people approached teaching about objects. We show that Junior successfully used transparency to mitigate errors. Finally, we present the impact of “social” versus “non-social” data sets when training SVM classifiers.
Effects of row spacing and seeding rates on some agronomical traits of spring canola (Brassica napus L.) cultivars.

The objective of the study was to evaluate the effects of row spacing and seeding rates on agronomical traits of three spring canola (Brassica napus L.) cultivars in Iran during 2003-2004. Traits evaluated were plant height, number of seeds pod-1, number of pods main stem-1, number of pods plant-1, 1000-seed weight, seed yield, and seed oil content. The experimental lay-out was split-split plot based on randomized complete block design with 4 replications. 3 row spacing of 12, 18 and 24 cm constituted the main plot, 2 seeding rates of 4 and 6 kg ha-1 as split plot and 3 spring canola cultivars of Hyola 401, Hyola 60 and RGS-003 (lately-used hybrid, new hybrid and new cultivar, respectively) comprised the split-split plot. Results showed that the highest seed yield was obtained at 12 cm row spacing, followed by 7.4% reduction in seed yield as row spacing increased to 24 cm. An increase in seeding rates from 4 to 6 kg ha-1 resulted in a decrease in number of pods plant-1 but other traits were not influenced. The highest number of pods plant-1 was obtained by applying 4 kg ha-1 seeding rates. The hybrid Hyola 401 had better performance than two other cultivars in plant height, number of grains pod-1, number of pods main stem-1, seed yield and seed oil content. The interaction of row spacing × seed rates and also row spacing × cultivars were significant only for the number of pods main stem-1. The lowest one was obtained at 12 cm row spacing with 6 kg ha -1 seed rates. RGS-003 at 12 cm row spacing showed the highest number of pods main stem-1, statistically equal to Hyola 401 grown at 24 cm row spacing.
Fast Event-based Corner Detection

Event cameras offer many advantages over standard frame-based cameras, such as low latency, high temporal resolution, and a high dynamic range. They respond to pixel- level brightness changes and, therefore, provide a sparse output. However, in textured scenes with rapid motion, millions of events are generated per second. Therefore, state- of-the-art event-based algorithms either require massive parallel computation (e.g., a GPU) or depart from the event-based processing paradigm. Inspired by frame-based pre-processing techniques that reduce an image to a set of features, which are typically the input to higher-level algorithms, we propose a method to reduce an event stream to a corner event stream. Our goal is twofold: extract relevant tracking information (corners do not suffer from the aperture problem) and decrease the event rate for later processing stages. Our event-based corner detector is very efficient due to its design principle, which consists of working on the Surface of Active Events (a map with the timestamp of the lat- est event at each pixel) using only comparison operations. Our method asynchronously processes event by event with very low latency. Our implementation is capable of pro- cessing millions of events per second on a single core (less than a micro-second per event) and reduces the event rate by a factor of 10 to 20.
Ufasomes Mediated Cutaneous Delivery of Dexamethasone: Formulation and Evaluation of Anti-Inflammatory Activity by Carrageenin-Induced Rat Paw Edema Model

The purpose of study is to formulate and evaluate ufasomal gel of dexamethasone. Ufasomal suspension was made by sonication method using different concentrations of Span 80, Span 20 and cholesterol along with 25 mg of drug. Ufasomal gel was formulated by hydration method using carbopol 940. Ufasomal vesicles appeared as spherical and multilamellar under Transmission Electron Microscope. Ufasomal formulation prepared with drug to oleic acid molar ratio 8:2 (UF-2) produced greater number of vesicles and greater entrapment efficiency. UF-2 was optimized for further evaluation. The transdermal permeation and skin partitioning of from optimized formulation was significantly higher (P < 0.05) as compared to plain drug and plain gel formulation which is due to presence of surfactant acting as permeation enhancer. Permeation of optimized formulation was found to be about 4.7 times higher than plain drug gel. Anti-inflammatory activity evaluated by inhibition Carrageenan induced rat paw edema model. Significant reduction of edema (P < 0.10) was observed in comparison to the commercial product. Hence oleic acid based vesicles can be used as alternate carrier for topical delivery.