Miracle-dz/UniFAR-FTUs huggingface dataset:
Trial-by-trial adjustments in control triggered by incidentally encoded semantic cues

Cognitive control mechanisms provide the flexibility to rapidly adapt to contextual demands. These contexts can be defined by top-down goals—but also by bottom-up perceptual factors, such as the location at which a visual stimulus appears. There are now several experiments reporting contextual control effects. Such experiments establish that contexts defined by low-level perceptual cues such as the location of a visual stimulus can lead to context-specific control, suggesting a relatively early focus for cognitive control. The current set of experiments involved a word–word interference task designed to assess whether a high-level cue, the semantic category to which a word belongs, can also facilitate contextual control. Indeed, participants exhibit a larger Flanker effect to items pertaining to a semantic category in which 75% of stimuli are incongruent than in response to items pertaining to a category in which 25% of stimuli are incongruent. Thus, both low-level and high-level stimulus features can affect the bottom-up engagement of cognitive control. The implications for current models of cognitive control are discussed.
An Ambulatory Gait Monitoring System with Activity Classification and Gait Parameter Calculation Based on a Single Foot Inertial Sensor

Goal: For healthcare and clinical use, ambulatory gait monitoring systems using inertial sensors have been developed to estimate the user gait parameters, such as walking speed, stride time, and stride length. However, to adapt the systems effectively to daily-life activities, they need to be able to classify the gait activities of daily-life to obtain the parameters for each activity. In this study, we propose a simple classification algorithm based on a single inertial sensor for ease of use, which classifies three major gait activities: leveled walk, ramp walk, and stair walk. Method: The classification can be performed with gait parameter estimation simultaneously. The developed system that includes classification and parameter estimation algorithms was evaluated with eight healthy subjects within a gait lab and on an outdoor daily-life walking course. Results: The results showed that the estimated gait parameters were comparable to existing studies (range of walking speed root mean square error: 0.059–0.129 m/s), and the classification accuracy was sufficiently high for all three gait activities: 98.5% for the indoor gait lab experiment and 95.5% for the outdoor complex daily-life walking course experiment. Conclusion: The proposed system is simple and effective for daily-life gait analysis, including gait activity classification and gait parameter estimation for each activity.
Nurses' perceptions and experiences of work role transitions: a mixed methods systematic review of the literature.

AIM To understand nurses' perceptions and experiences of work role transitions. BACKGROUND Globally an uncertain healthcare landscape exists and when changing work roles nurses experience periods of transition when they may not cope well. A greater understanding of work role transitions may help facilitate workforce retention and successful careers. DESIGN Mixed methods systematic review. DATA SOURCES Six data bases were searched for peer reviewed primary empirical research, published in English language between January 1990 and December 2014, supplemented by hand and citation searching. REVIEW METHODS Evidence for Policy and Practice Information and Co-ordinating Centre methods for systematic reviews principles were followed. Analysis and synthesis of the qualitative and quantitative papers was conducted separately using thematic analysis. A third synthesis combined the narrative findings and a narrative synthesis of results is presented. RESULTS Twenty-six papers were included. Across nurses' work role transitions two pathways were found: Novice and Experienced. 'Novice' comprises pre-registration and newly qualified nurses. 'Experienced' comprises, Enrolled/Licensed Practical Nurse to Registered Nurse, experienced to specialist nurse and clinical role changes. Each pathway results in different emphasizes of two themes; 'Striving for a new professional self' includes emotional upheaval and identity while 'Know how' includes competence and boundaries. Novice nurses are more susceptible to the extremes of emotional upheaval while experienced nurses' competence eases aspects of transitions while boundary issues pervade. CONCLUSION Informed work and educational environments are required for all groups of nurses. Using existing models of transition can facilitate successful individual transitions and develop the workplace.
REMOVAL OF HEAVY METALS USING BACTERIA ISOLATED FROM LIGNITE MINING ENVIRONMENT

In industrialized areas, high concentrations of heavy metals have been often found in effluent, soils and wastes, establishing a serious ecological risk. Microorganisms are the first biota that undergoes direct and indirect impacts of heavy metals. The present study was conducted to isolate the heavy metal resistant bacteria from metal rich soil from lignite mining site to assess its capacity to remove heavy metals. Five different bacterial strains were isolated and designated as HMB1, HMB2, HMB3, HMB4 and HMB5 and they were tested against different concentrations of heavy metals viz., Hg, Cr and Ni. Three different methods such as living cells, dead cells and immobilization techniques were used for assessment of capacity of all the five strains to remove metals from the solution containing 100 mg/L. The results of the present study indicated that the maximum heavy metal removal was found to be high in immobilization technique followed by dead cells and living cells. Among the five strains, the HMB2 was high efficient than the others strains in all the methods. Based on the morphological and biochemical characterization the strains were identified. The bacterial strain HMB1 was belonged to Bacillus sp. , the strain HMB2 was belonged to Bacillus subtilis, the strains HMB3 and HMB4 were belonged to Pseudomonas sp. and the strain HMB5 was belonged to Serratia sp. This indicated that the potential use of these bacterial isolates for removal of heavy metals from wastewater and industrial effluents containing higher concentration of heavy metals.
Beyond the pollination syndrome: nectar ecology and the role of diurnal and nocturnal pollinators in the reproductive success of Inga sessilis (Fabaceae).

Inga species present brush-type flower morphology allowing them to be visited by distinct groups of pollinators. Nectar features in relation to the main pollinators have seldom been studied in this genus. To test the hypothesis of floral adaptation to both diurnal and nocturnal pollinators, we studied the pollination ecology of Inga sessilis, with emphasis on the nectar secretion patterns, effects of sequential removals on nectar production, sugar composition and the role of diurnal and nocturnal pollinators in its reproductive success. Inga sessilis is self-incompatible and pollinated by hummingbirds, hawkmoths and bats. Fruit set under natural conditions is very low despite the fact that most stigmas receive polyads with sufficient pollen to fertilise all ovules in a flower. Nectar secretion starts in the bud stage and flowers continually secreting nectar for a period of 8 h. Flowers actively reabsorbed the nectar a few hours before senescence. Sugar production increased after nectar removal, especially when flowers were drained during the night. Nectar sugar composition changed over flower life span, from sucrose-dominant (just after flower opening, when hummingbirds were the main visitors) to hexose-rich (throughout the night, when bats and hawkmoths were the main visitors). Diurnal pollinators contributed less than nocturnal ones to fruit production, but the former were more constant and reliable visitors through time. Our results indicate I. sessilis has floral adaptations, beyond the morphology, that encompass both diurnal and nocturnal pollinator requirements, suggesting a complementary and mixed pollination system.
Pediatric EM Parents ’ willingness to have their child receive care by physician assistants in a pediatric emergency department

Objective: To determine the willingness of parents of children visiting a pediatric emergency department to have a physician assistant (PA) assess and treat their child and the waiting time reduction sufficient for them to choose to receive treatment by a PA rather than wait for a physician. Method: After describing the training and scope of practice of PAs, we asked caregivers of children triaged as urgent to nonurgent if they would be willing to have their child assessed and treated by a PA on that visit: definitely, maybe, or never. We also asked the minimum amount of waiting time reduction they would want to see before choosing to receive treatment by a PA rather than wait for a physician. Result: We approached 320 eligible subjects, and 273 (85.3%) consented to participate. Regarding whether they would be willing to have their child receive treatment by a PA, 140 (51.3%) respondents answered definitely, 107 (39.2%) said maybe, and 26 (9.2%) said never. Most respondents (64.1%) would choose to have their child seen by a PA instead of waiting for a physician if the waiting time reduction were at least 60 minutes (median 60 minutes [interquartile range 60 minutes]). Respondents’ perception of the severity of their child’s condition was associated with unwillingness to receive treatment by a PA, whereas child’s age, presenting complaint, and actual waiting time were not. Conclusion: Only a small minority of parents of children visiting a pediatric emergency department for urgent to nonurgent issues are unwilling to have their child treated by PAs.
Exercise intensity dependent relevance of protective textile properties for human thermo-physiology

During firefighting, thermoregulation is challenged due to a combination of harsh environmental conditions, high metabolic rates and personal protective clothing (PPC). Consequently, investigations of thermoregulation in firefighters should not only consider climate and exercise intensity, but technical properties of textiles too. Therefore, laboratory textile performance simulations may provide additional insights into textile-dependent thermoregulatory responses to exercise. In order to investigate the thermo-physiological relevance of textile properties and to test how different garments affect thermoregulation at different exercise intensities, we analyzed the results of a standard laboratory test and human subject trials by relating functional properties of textiles to thermo-physiological responses. Ten professional, healthy, male firefighters (age: 43 ± 6 y, weight: 84.3 ± 10.3kg, height: 1.79 ± 0.05m) performed low and moderate intensity exercise wearing garments previously evaluated with a sweating torso system to characterize thermal and evaporative properties. Functional properties of PPC and the control garment differed markedly. Consequently, skin temperature was higher using PPC at both exercise intensities (low: 36.27 ± 0.32 versus 36.75 ± 0.15℃, P < 0.05; moderate: 36.53 ± 0.34 versus 37.18 ± 0.23℃, P < 0.001), while core body temperature was only higher for PPC at moderate (37.54 ± 0.24 versus 37.83 ± 0.27℃, P < 0.05), but not low-intensity exercise (37.26 ± 0.21 versus 37.21 ± 0.19, P = 0.685). Differences in thermal and evaporative properties between textiles are reflected in thermo-physiological responses during human subject trials. However, an appropriate exercise intensity has to be chosen in order to challenge textile performance during exercise tests.
Exploring faecal incontinence in nursing home patients: a cross-sectional study of prevalence and associations derived from the Residents Assessment Instrument for Long-Term Care Facilities.

AIM To explore prevalence and associations of faecal incontinence among nursing home patients, to examine the effect of clustering of observations and to study the variation in faecal incontinence rates on both the level of nursing home units and individual patients. BACKGROUND Faecal incontinence affects 40-55% of the patients in nursing homes and is associated with increased risk of morbidity and reduced quality of life. There is a lack of studies investigating faecal incontinence with validated instruments. More studies need to include models of analyses that allow for clustering of observations. DESIGN Cross-sectional. METHODS Data on 261 patients from 20 nursing home units were collected during September-October 2014. The Norwegian version of the Resident Assessment Instrument for Long-Term Care Facilities was used. Mixed effect models were conducted. RESULTS Prevalence of faecal incontinence was 42·1% or 54% depending on the frequency labelling chosen. The effect of clustering by nursing home unit was not statistically significant. Most of the variation in faecal incontinence rates was explained by differences in patient characteristics, the most important being deficiencies in activities of daily living, cognitive impairment, diarrhoea and not participating in activities. CONCLUSION Nursing home patients should be offered individualized assessment and continence care matching their patient characteristics. The Resident Assessment Instrument for Long-Term Care Facilities is a useful instrument because of its' combination of a comprehensive range of individual items and scales allowing for comparison of immediate or long-term change in patients status. Studies evaluating interventions targeting faecal incontinence are warranted.
QARAB: A: Question Answering System to Support the Arabic Language

We describe the design and implementation of a question answering (QA) system called QARAB. It is a system that takes natural language questions expressed in the Arabic language and attempts to provide short answers. The system's primary source of knowledge is a collection of Arabic newspaper text extracted from Al-Raya, a newspaper published in Qatar. During the last few years the information retrieval community has attacked this problem for English using standard IR techniques with only mediocre success. We are tackling this problem for Arabic using traditional Information Retrieval (IR) techniques coupled with a sophisticated Natural Language Processing (NLP) approach. To identify the answer, we adopt a keyword matching strategy along with matching simple structures extracted from both the question and the candidate documents selected by the IR system. To achieve this goal, we use an existing tagger to identify proper names and other crucial lexical items and build lexical entries for them on the fly. We also carry out an analysis of Arabic question forms and attempt a better understanding of what kinds of answers users find satisfactory. The paucity of studies of real users has limited results in earlier research.
Experimental study on oral sulfhydryl as an adjuvant for improving nitrate ester tolerance in an animal model.

OBJECTIVE As an initial step in exploring the feasibility of oral sulfhydryl as an adjuvant for improving nitrate ester tolerance, this study was designed to experimentally test the adjuvant therapy in a rabbit model of atherosclerosis (AS). MATERIALS AND METHODS New Zealand white rabbits with induced AS were randomly divided into four groups: AS group, AS + nitrate ester group, AS + nitrate ester tolerance group, and AS + drug combination group. Additionally, four equivalent groups with healthy New Zealand white rabbits without AS were also conformed. After feeding the animals for 5 days, the concentrations of superoxide anion (•O2-), superoxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO), and endothelin-1 (ET-1) in blood and the relaxation response of the aortic ring were determined in each subject. The vascular plaques in different treatment groups were assessed by Hematoxylin and eosin (HE) staining to investigate the therapeutic value of sulfhydryl as coadjuvant for improving nitrate ester tolerance, and changes in blood vessels in different treatment groups were studied by immunohistochemical assays. RESULTS Our results showed no significant differences through time in the concentrations of •O2-, SOD, MDA, NO, ET-1 between the healthy control and the nitrate ester groups (p > 0.05). The levels of SOD and MDA in the nitrate ester tolerance group increased with time, however, the levels of •O2-, NO and ET-1 decreased gradually (p < 0.05). The NO, •O2- and ET-1 levels in both the AS and AS + nitrate ester tolerance groups were significantly decreased, but SOD and MDA were significantly increased (p < 0.05). SOD and MDA in the AS + nitrate ester group decreased gradually with time, but •O2-, NO- and ET-1 levels increased (p < 0.05). The levels of SOD and MDA in the AS + drug combination and the drug combination group decreased significantly with time, in contrast, those of •O2-, NO- and ET-1 increased (p < 0.05). The results of HE staining proved that the atherosclerosis model was established successfully. CONCLUSIONS We conclude the use of a sulfhydryl compound as an adjuvant significantly reduced nitrate ester tolerance, and this strategy was safe and looks promising for humans.
The Speed of Light

You have probably heard that nothing can go faster than the speed of light. In this chapter, we will see that the speed of light is even more remarkable: it is the same in all frames. From this surprising fact, we will deduce that this speed must also serve as a limit and that Galilean velocity addition fails to describe how nature works at high speeds: our first glimpses of the modern understanding of relativity. To make you more comfortable with the fact that velocities must add nonlinearly, this chapter develops an intuitive conceptual analogy for velocity addition.
Quality of life in long-term, disease-free survivors of breast cancer: a follow-up study.

BACKGROUND Women with breast cancer are the largest group of female survivors of cancer. There is limited information about the long-term quality of life (QOL) in disease-free breast cancer survivors. METHODS Letters of invitation were mailed to 1336 breast cancer survivors who had participated in an earlier survey and now were between 5 and 10 years after their initial diagnosis. The 914 respondents interested in participating were then sent a survey booklet that assessed a broad range of QOL and survivorship concerns. All P values were two-sided. RESULTS A total of 817 women completed the follow-up survey (61% response rate), and the 763 disease-free survivors in that group, who had been diagnosed an average of 6.3 years earlier, are the focus of this article. Physical well-being and emotional well-being were excellent; the minimal changes between the baseline and follow-up assessments reflected expected age-related changes. Energy level and social functioning were unchanged. Hot flashes, night sweats, vaginal discharge, and breast sensitivity were less frequent. Symptoms of vaginal dryness and urinary incontinence were increased. Sexual activity with a partner declined statistically significantly between the two assessments (from 65% to 55%, P =.001). Survivors with no past systemic adjuvant therapy had a better QOL than those who had received systemic adjuvant therapy (chemotherapy, tamoxifen, or both together) (physical functioning, P =.003; physical role function, P =.02; bodily pain, P =.01; social functioning, P =.02; and general health, P =.03). In a multivariate analysis, past chemotherapy was a statistically significant predictor of a poorer current QOL (P =.003). CONCLUSIONS Long-term, disease-free breast cancer survivors reported high levels of functioning and QOL many years after primary treatment. However, past systemic adjuvant treatment was associated with poorer functioning on several dimensions of QOL. This information may be useful to patients and physicians who are engaging in discussion of the risks and benefits of systemic adjuvant therapy.
Dimensional changes in the palate associated with slow maxillary expansion for early treatment of posterior crossbite.

OBJECTIVES To compare palatal symmetry, dimensions, and molar angulations following early mixed-dentition slow maxillary expansion with parameters in normal controls. MATERIALS AND METHODS A total of 30 patients treated with a Haas-type expander for unilateral posterior crossbite with functional shift were compared with 30 controls matched for dental age, gender, and molar relationship. Records were taken before (T1) and after expansion (T2). Palatal width, surface area, volume, and molar angulations were measured on digitized models. Surface area and volume were split in half then divided into anterior, middle, and posterior segments to measure symmetry. Student's t-test was used to assess group differences. RESULTS Mean intercanine width increased 4.65 mm, and intermolar width increased 4.76 mm. The treated mean surface area increased 127.05 mm2 compared with 10.35 mm2 in controls. The treated palatal volume increased 927.55 mm3 compared with 159.89 mm3 for controls. At T1, the controls showed significant differences in surface area and volume between the anterior palatal segments. At T2, this difference occurred in surface area of middle palatal segments of the treated sample. First permanent molars showed an increased buccal and distal inclination after treatment, opposite to controls. The increase in buccal inclination was greater on the crossbite side. CONCLUSIONS The Haas-type expander results in similar expansion across the canines and first molars. A palate that is symmetrical before expansion may become asymmetric after expansion but only in the middle segment. Changes in individual molar angulation following palatal expansion can be measured without radiation imaging.
Development and Validation of a HPLC-ESI-MS/MS Method for Simultaneous Quantification of Fourteen Alkaloids in Mouse Plasma after Oral Administration of the Extract of Corydalis yanhusuo Tuber: Application to Pharmacokinetic Study

The tuber of Corydalis yanhusuo is a famous traditional Chinese medicine and found to have potent pharmacological effects, such as antinociceptive, antitumor, antibacterial, anti-inflammatory, and anti-depressive activities. Although there are several methods to be developed for the analysis and detection of the bioactive ingredients’ alkaloids, so far, only few prominent alkaloids could be quantified, and in vitro and in vivo changes of comprehensive alkaloids after oral administration are still little known. In this study, we first developed a simple and sensitive high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) method to quantify the comprehensive alkaloids of extracts of C. yanhusuo in mouse plasma, using nitidine chloride as an internal standard. As results, at least fourteen alkaloids, including an aporphine (oxoglaucine), a protopine (protopine), five tertiary alkaloids (corydaline, tetrahydroberberine, tetrahydropalmatine, tetrahydrocolumbamine, and tetrahydrocoptisine) and seven quaternary alkaloids (columbamine, palmatine, berberine, epiberberine, coptisine, jatrorrhizine, and dehydrocorydaline) could be well quantified simultaneously in mouse plasma. The lower limits of quantification were greater than, or equal to, 0.67 ng/mL, and the average matrix effects ranged from 96.4% to 114.3%. The mean extraction recoveries of quality control samples were over 71.40%, and the precision and accuracy were within the acceptable limits. All the analytes were shown to be stable under different storage conditions. Then the established method was successfully applied to investigate the pharmacokinetics of these alkaloids after oral administration of the extract of Corydalis yanhusuo in mice. To the best of our knowledge, this is the first document to report the comprehensive and simultaneous analyses of alkaloids of C. yanhusuo in mouse plasma. It was efficient and useful for comprehensive pharmacokinetic and metabolomic analyses of these complex alkaloids after drug administration.