Miracle-dz/UniFAR-FTUs huggingface dataset:
Non-Contributory Pensions

The creation of non-contributory pension schemes is becoming increasingly common as countries struggle to reduce poverty. Drawing on data from Mexico's Adultos Mayores Program (Older Adults Program) --a cash transfer scheme aimed at rural adults over 70 years of age-- we evaluate the effects of this program on the well-being of the beneficiary population. Exploiting a quasi-experimental design whereby the program relies on exogenous geographical and age cutoffs to identify its target group, we find that the mental health of elderly adults in the program is significantly improved, as their score on the Geriatric Depression Scale decreases by 12%. We also find that the proportion of treated individuals doing paid work is reduced by 20%, with most of these people switching from their former activities to work in family businesses; treated households show higher levels of consumption expenditures (on average, an increase of 23%). Very importantly, we also rule out significant anticipation effects that might have been associated with the program transfers. Thus, overall, we find that non-contributory pension schemes target to the poor in developing countries can improve the well-being of poor older adults without having any indirect impact (through potential anticipation effects) on the earnings or savings of future program participants.
Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review

Recently, a range of prescription and over-the-counter drugs have been reportedly used as Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their high dosage/idiosyncratic methods of self-administration. This paper provides a systematic review of the topic, focusing on a range of medications which have emerged as being used recreationally, either on their own or in combination with NPS. Among gabapentinoids, pregabalin may present with higher addictive liability levels than gabapentin, with pregabalin being mostly identified in the context of opioid, polydrug intake. For antidepressants, their dopaminergic, stimulant-like, bupropion activities may explain their recreational value and diversion from the therapeutic intended use. In some vulnerable clients, a high dosage of venlafaxine (‘baby ecstasy’) is ingested for recreational purposes, whilst the occurrence of a clinically-relevant withdrawal syndrome may be a significant issue for all venlafaxine-treated patients. Considering second generation antipsychotics, olanzapine appears to be ingested at very large dosages as an ‘ideal trip terminator’, whilst the immediate-release quetiapine formulation may possess proper abuse liability levels. Within the image- and performance- enhancing drugs (IPEDs) group, the beta-2 agonist clenbuterol (‘size zero pill’) is reported to be self-administered for aggressive slimming purposes. Finally, high/very high dosage ingestion of the antidiarrhoeal loperamide has shown recent increasing levels of popularity due to its central recreational, anti-withdrawal, opiatergic effects. The emerging abuse of prescription drugs within the context of a rapidly modifying drug scenario represents a challenge for psychiatry, public health and drug-control policies.
A Prospective Evaluation of Health-Related Quality of Life following Lymphaticovenular Anastomosis for Upper and Lower Extremities Lymphedema

Abstract Background Lymphedema is a progressive disease that negatively affects body image and physical, psychological, and social functions. There is lack of evidence in the present literature about the impact of super microsurgical lymphaticovenular anastomosis (LVA) on health-related quality of life (HRQoL). The aim of this prospective study is to report the outcomes of patients' HRQoL after LVA for lower and upper extremities lymphedema. Methods Between September 2015 and February 2017, 74 patients with upper or lower limb lymphedema (ULL or LLL) underwent LVA at our center. Quality of life (QoL) was assessed by lymphedema QoL questionnaire (LyMQoL), which is a validated disease-specific instrument to measure the impact of lymphedema on patient's lives, covering four domains: function, body image, symptoms, and mood. All patients were evaluated preoperatively, 1 month after surgery, and every 3 months up to 1 year. Additionally, we evaluated the episodes of lymphangitis and the need for conservative therapy before and after surgery. Results After a mean follow-up of 8.5 months (range: 2–21 months), we observed an increase of 2.3 points in the overall QoL average for upper limb and 2.6 points for lower limb (p < 0.001). A statistically significant improvement in all four domains (p < 0.01) was reported after surgery, being present from the first postoperative months for both upper and lower extremities. Conclusion Our study shows that lymphaticovenular anastomosis improves HRQoL in patients affected by ULL and LLL. Additionally, both a reduction of episodes of lymphangitis and a decrease in the need of conservative therapy were observed in this cohort of patients.
TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs

Background: Variation in genes implicated in monoamine neurotransmission may interact with environmental factors to influence antidepressant response. We aimed to determine how a range of single nucleotide polymorphisms in monoaminergic genes influence this response to treatment and how they interact with childhood trauma and recent life stress in a Chinese sample. An initial study of monoaminergic coding region single nucleotide polymorphisms identified significant associations of TPH2 and HTR1B single nucleotide polymorphisms with treatment response that showed interactions with childhood and recent life stress, respectively (Xu et al., 2012). Methods: A total of 47 further single nucleotide polymorphisms in 17 candidate monoaminergic genes were genotyped in 281 Chinese Han patients with major depressive disorder. Response to 6 weeks’ antidepressant treatment was determined by change in the 17-item Hamilton Depression Rating Scale score, and previous stressful events were evaluated by the Life Events Scale and Childhood Trauma Questionnaire-Short Form. Results: Three TPH2 single nucleotide polymorphisms (rs11178998, rs7963717, and rs2171363) were significantly associated with antidepressant response in this Chinese sample, as was a haplotype in TPH2 (rs2171363 and rs1487278). One of these, rs2171363, showed a significant interaction with childhood adversity in its association with antidepressant response. Conclusions: These findings provide further evidence that variation in TPH2 is associated with antidepressant response and may also interact with childhood trauma to influence outcome of antidepressant treatment.
Exergy Analyses of Onion Drying by Convection: Influence of Dryer Parameters on Performance

This research work is concerned in the exergy analysis of the continuous-convection drying of onion. The influence of temperature and air velocity was studied in terms of exergy parameters. The energy and exergy balances were carried out taking into account the onion drying chamber. Its behavior was analyzed based on exergy efficiency, exergy loss rate, exergetic improvement potential rate, and sustainability index. The exergy loss rates increase with the temperature and air velocity augmentation. Exergy loss rate is influenced by the drying air temperatures and velocities because the overall heat transfer coefficient varies with these operation conditions. On the other hand, the exergy efficiency increases with the air velocity augmentation. This behavior is due to the energy utilization was improved because the most amount of supplied energy was utilized for the moisture evaporation. However, the exergy efficiency decreases with the temperature augmentation due to the free moisture being lower, then, the moisture begins diffusing from the internal structure to the surface. The exergetic improvement potential rate values show that the exergy efficiency of onion drying process can be ameliorated. The sustainability index of the drying chamber varied from 1.9 to 5.1. To reduce the process environmental impact, the parameters must be modified in order to ameliorate the exergy efficiency of the process.
Seeing Emotion with Your Ears: Emotional Prosody Implicitly Guides Visual Attention to Faces

Interpersonal communication involves the processing of multimodal emotional cues, particularly facial expressions (visual modality) and emotional speech prosody (auditory modality) which can interact during information processing. Here, we investigated whether the implicit processing of emotional prosody systematically influences gaze behavior to facial expressions of emotion. We analyzed the eye movements of 31 participants as they scanned a visual array of four emotional faces portraying fear, anger, happiness, and neutrality, while listening to an emotionally-inflected pseudo-utterance (Someone migged the pazing) uttered in a congruent or incongruent tone. Participants heard the emotional utterance during the first 1250 milliseconds of a five-second visual array and then performed an immediate recall decision about the face they had just seen. The frequency and duration of first saccades and of total looks in three temporal windows ([0–1250 ms], [1250–2500 ms], [2500–5000 ms]) were analyzed according to the emotional content of faces and voices. Results showed that participants looked longer and more frequently at faces that matched the prosody in all three time windows (emotion congruency effect), although this effect was often emotion-specific (with greatest effects for fear). Effects of prosody on visual attention to faces persisted over time and could be detected long after the auditory information was no longer present. These data imply that emotional prosody is processed automatically during communication and that these cues play a critical role in how humans respond to related visual cues in the environment, such as facial expressions.
Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells

ABSTRACT Trypanosoma cruzi, the aetiologic agent of Chagas disease, releases vesicles containing a wide range of surface molecules known to affect the host immunological responses and the cellular infectivity. Here, we compared the secretome of two distinct strains (Y and YuYu) of T. cruzi, which were previously shown to differentially modulate host innate and acquired immune responses. Tissue culture-derived trypomastigotes of both strains secreted extracellular vesicles (EVs), as demonstrated by electron scanning microscopy. EVs were purified by exclusion chromatography or ultracentrifugation and quantitated using nanoparticle tracking analysis. Trypomastigotes from YuYu strain released higher number of EVs than those from Y strain, enriched with virulence factors trans-sialidase (TS) and cruzipain. Proteomic analysis confirmed the increased abundance of proteins coded by the TS gene family, mucin-like glycoproteins, and some typical exosomal proteins in the YuYu strain, which also showed considerable differences between purified EVs and vesicle-free fraction as compared to the Y strain. To evaluate whether such differences were related to parasite infectivity, J774 macrophages and LLC-MK2 kidney cells were preincubated with purified EVs from both strains and then infected with Y strain trypomastigotes. EVs released by YuYu strain caused a lower infection but higher intracellular proliferation in J774 macrophages than EVs from Y strain. In contrast, YuYu strain-derived EVs caused higher infection of LLC-MK2 cells than Y strain-derived EVs. In conclusion, quantitative and qualitative differences in EVs and secreted proteins from different T. cruzi strains may correlate with infectivity/virulence during the host–parasite interaction.
Novel Gold Dendritic Nanoforests Combined with Titanium Nitride for Visible-Light-Enhanced Chemical Degradation

In this study, gold dendritic nanoforests (Au DNFs)-titanium nitride (TiN) composite was firstly proposed for visible-light photodegradation of pollutants. A high-power impulse magnetron sputtering system was used to coat TiN films on silicon wafers, and a fluoride-assisted galvanic replacement reaction was applied to deposit Au DNFs on TiN/Si substrates. Scanning electron microscope images and X-ray diffraction patterns of TiN/Si, Au DNFs/Si, and Au DNFs/TiN/Si samples verified that this synthesis process was accurately controlled. The average reflectance of Au DNFs/Si and Au DNFs/TiN/Si considerably declined to approximately 10%, because the broadband localized surface plasmon resonances of Au DNFs cause broadband absorbance and low reflectance. In photocatalytic performance, 90.66 ± 1.41% 4-nitrophenol was successfully degraded in 180 min by Au DNFs/TiN/Si under visible-light irradiation. Therefore, Au DNFs/TiN/Si has the chance to be a visible-light photocatalyst for photodegradation of pollutants.
The Importance of Being Important: Theoretical Models of Relations between Specific and Global Components of Physical Self-Concept

Theoretical models of relations between specific components of physical self-concept, global physical self-concept, and global esteem are evaluated. Self-concept models posit that the effect of a specific domain (e.g., strength, endurance, or appearance) on global components should vary with the importance an individual places on the specific domain, but empirical support for this prediction is weak. Fox (1990) incorporated a related assumption into his hierarchical model of physical self-concept, but did not test this assumption. In empirical tests based on responses to the newly developed Physical Self-Description Questionnaire, relations between specific and global components of physical self-concept did not vary with the perceived importance of the specific component, and unweighted averages of specific components were as highly related to global components as importance weighted averages. These results provide no support for the importance of importance in modifying relations between domain-specific .
Full Frame Encryption and Modulation Obfuscation Using Channel-Independent Preamble Identifier

The broadcast nature of wireless communications exposes various transmission attributes, such as the packet size, inter-packet times, and the modulation scheme. These attributes can be exploited by an adversary to launch passive (e.g., traffic analysis) or selective jamming attacks. This security problem is present even when frame headers and payloads can be encrypted. For example, by determining the modulation scheme, the attacker can estimate the data rate, and hence the payload size. In this paper, we propose Friendly CryptoJam (FCJ), a scheme that decorrelates the payload's modulation scheme from other transmission attributes by embedding information symbols into the constellation map of the highest-order modulation scheme supported by the system (a concept we refer to as indistinguishable modulation unification). Such unification is done using the least-complex trellis-coded modulation schemes, which are combined with a secret pseudo-random sequence in FCJ to conceal the rate-dependent pattern imposed by the code. It also preserves the bit error rate performance of the payload's original modulation scheme. At the same time, modulated symbols are encrypted to hide PHY-/MAC layer fields. To identify the Tx and synchronously generate the secret sequence at the Tx and Rx, an efficient identifier embedding technique based on Barker sequences is proposed, which exploits the structure of the preamble and overlays a frame-specific identifier on it. We study the implications of the scheme on PHY-layer functions through simulations and testbed experiments. Our results confirm the efficiency of FCJ in hiding the targeted attributes.
“You're Going Out with Who?”: Peer Group Influences on Adolescent Romantic Relationships

One of the hallmarks of American adolescence is the broadening and intensification of peer relationships (Brown, 1990; Hartup, 1993). During this life stage young people typically expand the time spent with peers, rely more on peers for advice and support, and work out their identities and aspirations within the context of peer relationships. The peer system itself expands, most notably with a new form of dyadic association: romantic relationships. To a limited extent, researchers have explored various facets of this new form of relationship: its connection to family structure and processes, its impact on the emotional and sexual lives of young people, its associations with participants' personal characteristics such as sex role orientation or attachment style, and its role in the social mandate of mate selection and marriage. Rarely, however, have researchers given concurrent attention to two other critical components of adolescent romantic relationships: the social context in which they are primarily embedded, that is, the social world of peers and the changes or metamorphosis that they manifest across adolescence. Both of these components are addressed in several other contributions to this volume, but they are the focal interests of this chapter.
Nearby farms are a source of lice for wild salmonids: a reply to Jansen et al. (2016)

Jansen et al. (2016; Aquacult Environ Interact 8:349�350) question the regression analysis presented in Serra-Llinares et al. (2014; Aquacult Environ Interact 5:1�16), which corre- lates lice abundances on farmed and wild fish. Jansen et al. (2016) argue that the correlation might not reflect a cause-effect relationship but be instead a mere artifact of the spatio-temporal covari- ance in lice abundance on farmed and wild fish driven by temperature. In this Reply Comment we revisit the analysis presented in Serra-Llinares et al. (2014) and further re-analyze our data follow- ing the statistical approach used by Helland et al. (2015; Aquacult Environ Interact 7:267�280), to rule out the potential confounding effect of temperature. We conclude that Jansen et al. (2016) were correct in conveying part of the observed correlation to the effect of temperature; however, there is solid evidence of a significant influence of lice originating from nearby farms on the observed lice abundances on wild fish, even after the effect of temperature is accounted for.
The Correlation Between Perceived Stress and Health Promoting Self-care Behaviors in High-risk Third Trimester Pregnancies

The purpose of this study was to explore the impact of maternal perceived stress in high-risk pregnancy on participation in health promoting self-care. Orem’s self-care deficit theory of nursing was the theoretical framework. A secondary analysis from a convenience sample of 69 women experiencing a high-risk pregnancy was conducted. The correlation between the Perceived Stress Scale by Cohen and associates (1983) and the Health Promoting Lifestyle Profile II by Walker and associates (1987, 1997) was negative. The findings indicated that women in the third trimester of a high-risk pregnancy with higher perceived stress levels were less likely to be involved in health promoting self-care behaviors, specifically in the areas of spiritual growth, interpersonal relations, and stress management. These findings suggest that nursing can be beneficial to decrease stress for the high-risk pregnant woman by implementing interventions, which offer support, stress management, and an opportunity for spiritual growth.
A common medical error: lung cancer misdiagnosed as sputum negative tuberculosis.

OBJECTIVE To emphasize that delay in diagnosis of lung cancer can be caused by the wrong diagnosis of tuberculosis (TB) in TB endemic countries. This is of major concern as early-diagnosis of lung cancer can increase the chance of tumor resectability and timely chemo-radiotherapy may provide better quality of life. METHODS Proven lung cancer patients, who had received anti-tubercular treatment (ATT) since onset of current symptoms, were studied retrospectively during the period of Nov-07 to Nov-08. DATA-SOURCE: Patient interview and medical records. RESULTS Total of 14 out of 70 patients received wrong diagnosis of TB and had received ATT (male-12, female-2; mean age 58.07-/+6.81; Non Small Cell Lung Cancer (NSCLC) -12, Small Cell Lung Cancer (SCLC) -2), 12 were smokers with median smoking pack-years of 44(15 to 112). Pre-referral sputum acid fast bacilli (AFB) was done in only 3 out of these 14 patients and sputum AFB was negative in these 3 patients. ATT was started on the basis of chest X-ray finding and clinical symptoms. Mean duration of ATT taken was 4.46-/+3.15 months. CONCLUSION Due to high TB prevalence and radiological similarities, a large number of lung cancer patients initially get wrongly treated for TB. Also, clinicians associate lung cancer with high case-fatality and start ATT without detailed investigation. Altogether, this leads to delay in diagnosis and progression of disease.
The microbiota in inflammatory bowel disease: current and therapeutic insights

Inflammatory bowel disease is a heterogeneous group of chronic disorders that result from the interaction of the intestinal immune system with the gut microbiome. Until recently, most investigative efforts and therapeutic breakthroughs were centered on understanding and manipulating the altered mucosal immune response that characterizes these diseases. However, more recent studies have highlighted the important role of environmental factors, and in particular the microbiota, in disease onset and disease exacerbation. Advances in genomic sequencing technology and bioinformatics have facilitated an explosion of investigative inquiries into the composition and function of the intestinal microbiome in health and disease and have advanced our understanding of the interplay between the gut microbiota and the host immune system. The gut microbiome is dynamic and changes with age and in response to diet, antibiotics and other environmental factors, and these alterations in the microbiome contribute to disease onset and exacerbation. Strategies to manipulate the microbiome through diet, probiotics, antibiotics or fecal microbiota transplantation may potentially be used therapeutically to influence modulate disease activity. This review will characterize the factors involved in the development of the intestinal microbiome and will describe the typical alterations in the microbiota that are characteristic of inflammatory bowel disease. Additionally, this manuscript will summarize the early but promising literature on the role of the gut microbiota in the pathogenesis of inflammatory bowel disease with implications for utilizing this data for diagnostic or therapeutic application in the clinical management of patients with these diseases.
The Development of Native Chinese Affective Picture System-A pretest in 46 College Students

Objective: To develop the native Chinese Affective Picture System (CAPS) for future research on emotion. Methods: 852 pictures were screened out to make up of CAPS. 46 Chinese university students were collected to rate the valence, arousal and dominance by self-report in a 9-point rating scale for CAPS. Results: The standard deviations of scores on valence and dominance were greater than that on arousal. Scatter plot showed that the score distribution on the dimension of valence and arousal was wide in CAPS. Conclusion: Though IAPS (International Affective Picture System) is highly internationally-accessible, there are still significant differences between the two sources. The native Chinese Affective Picture System is necessary.