Miracle-dz/UniFAR-FTUs huggingface dataset:
Management and Prognosis of Clear Cell Borderline Ovarian Tumor

Background The clear cell borderline ovarian tumor (CCBOT) of the ovary is a rare tumor accounting for less than 1% of BOT. Fewer than 25 cases have been reported in the literature (including details on clinical management and outcomes). The aim of this study was to determine the prognosis of a series of CCBOTs collected in 2 reference centers. Patients and Methods This was a retrospective review of patients with CCBOT treated or referred to our institutions. A centralized histological review by a reference pathologist and data on the clinical characteristics, management, and outcomes of patients were required for inclusion. Results Twelve patients were identified between 2000 and 2010. The median age of patients was 68 years (range, 36–83 years). Two had been treated conservatively and 9 radically (data unknown in 1). The tumor was unilateral in 11 cases. All patients had stage I disease. All cases were CCBOT with an adenofibromatous pattern. Stromal microinvasion or intraepithelial carcinoma was histologically associated in 2 and 3 cases, respectively. Four of the 12 patients had synchronous endometrial disorders (but no endometrioid carcinoma). No cases were histologically associated with endometriosis. Four patients were lost to follow-up. Among 8 other patients, after a median period of 28 months (range, 2–129 months), no recurrence had occurred (1 patient had died of another disease). Conclusion Clear cell borderline ovarian tumor carries a good prognosis. All tumors are stage I; therefore, surgical staging is not necessary in most of the cases. Conservative treatment could be proposed to young patients, but uterine curettage would then be required in cases of uterine preservation.
A SIMPLE PLAN, A SIMPLE FAITH: CHAPLAINS AND LAY MINISTERS IN MISSISSIPPI PRISONS

As prisons across the United States increasingly utilize faith-based programs under the auspices of correctional treatment, investigators have studied how these programs impact the attitudes and behaviors of inmates while in prison and after release. Little is known, howevex about the ministry workers responsible for the provision of these faith-based prison programs. We address this understudied issue using the rich narratives of thirty prison chaplains and local religious congregants in Mississippi. Two overarching themes emerged from their narratives of prison ministry work. First, chaplains and local congregants have a distinctive goal orientation that discourages the creation of numeric goals for their ministry. Second, the ministry workers are careful to avoid specific denominational issues that might create barriers to inmates' religious involvement or that might create security issues. This study provides an in-depth understanding of the motivations and approaches used by this understudied group.
Modulation of Peripheral Nerve Regeneration: A Tissue-Engineering Approach. The Role of Amnion Tube Nerve Conduit across a 1-Centimeter Nerve Gap

A new type of a biodegradable nerve graft conduit material, the amnion tube, has been developed in our laboratory. To test the tube in the peripheral nerve regeneration process, it was initially applied across a 1-cm sciatic nerve gap in rats and was compared with other nerve conduit materials. We used male Sprague-Dawley rats as our animal model. The experiment included 66 rats that were randomly assigned into five groups: autograft (n = 17), amnion tube (n = 19), silicone tube (n = 20), no repair (n = 7), and sham group (n = 3). The process of peripheral nerve regeneration was evaluated at 2, 4, 10, and 17 weeks following injury and repair by using morphologic and functional assessments of the outcome of nerve regeneration in each animal. Nerve regeneration across the amnion tube nerve conduit was comparable with that seen in autograft and superior to that of the silicone group. A uniform nerve tissue was seen filling and crossing the amnion conduit, and the regenerated nerve from the proximal stump reached the distal end and was undifferentiated from the normal nerve tissues. At 4 months, the amnion tube biodegraded and no longer could be identified and differentiated from the nerve tissues. The amnion tube animal group showed a number of axons very close to that in the nerve autograft group (37,157 versus 33,054). Functional recovery at a 2- to 4-week interval was significantly statistically higher only in the amnion tube animal group (p = 0.01). However, the improvement disappeared between 10 and 17 weeks. In conclusion, the amnion tube is a potential ideal nerve conduit material secondary to its unique characteristics: it contains important neurotropic factors, is biodegradable, provokes a very weak immune response, is semiflexible, is readily available, and is easily manufactured into different sizes and diameters. (Plast. Reconstr. Surg. 105: 660, 2000.)
Problems Related to Underservice: A Rejoinder

Objective data provide overwhelming evidence that children and youth with emotional and behavioral disorders (EBD) are underidentified and underserved. This was the central argument in our November 2007 Forum article to which Harry, Hart, Klingner, Cramer, and Sturges responded. In this rejoinder, we continue to assert the dramatic need to offer appropriate educational services to all children with EBD independent of their personal identity and characteristics. Although we identify areas of agreement with Harry et al., we challenge many of their assertions related to our article and continue to affirm that underservice of learners with EBD is the greatest challenge.
A Review of Digital Techniques for Modeling Vacuum-Tube Guitar Amplifiers

Although semiconductor technologies have displaced vacuum-tube devices in nearly all fields of electronics, vacuum tubes are still widely used in professional guitar amplifiers. A major reason for this is that electric-guitar amplifiers are typically overdriven, that is, operated in such a way that the output saturates. Vacuum tubes distort the signal in a different manner compared to solid-state electronics, and human listeners tend to prefer this. This might be because the distinctive tone of tube amplifiers was popularized in the 1950s and 1960s by early rock and roll bands, so musicians and listeners have become accustomed to tube distortion. Some studies on the perceptual aspects of vacuum-tube and solid-state distortion have been published (e.g., Hamm 1973; Bussey and Haigler 1981; Santo 1994). Despite their acclaimed tone, vacuum-tube amplifiers have certain shortcomings: large size and weight, poor durability, high power consumption, high price, and often poor availability of spare parts. Thus, it is not surprising that many attempts have been made to emulate guitar tube amplifiers using smaller and cheaper solid-state analog circuits (e.g., Todokoro 1976; Sondermeyer 1984). The next step in the evolution of tube-amplifier emulation has been to simulate the amplifiers using computers and digital signal processors (DSP). A primary advantage of digital emulation is that the same hardware can be used for modeling many different tube amplifiers and effects. When a new model is to be added, new parameter values or program code are simply uploaded to the device. Furthermore, amplifier models can be implemented
Dietary antioxidant intake and the risk of cardia cancer and noncardia cancer of the intestinal and diffuse types: A population‐based case‐control study in Sweden

In spite of diverging incidence trends, subsite, and subtype‐specific gastric cancer data on the association with dietary antioxidants are sparse. We aimed to test whether the apparent protective effect of antioxidants is mainly confined to noncardia (distal) cancer of the intestinal subtype, to which most of the incidence decline in gastric cancer has been ascribed. In a Swedish study base (total population 1.3 million), we interviewed 567 cases uniformly classified to subsite (cardia vs. noncardia) and subtype (intestinal vs. diffuse), and 1165 population‐based controls, frequency matched for age and sex. Serologic data on H. pylori status was available for a subset of 542 individuals. Ascorbic acid (vitamin C) was inversely associated with all subsites and subtypes of gastric cancer in a significant dose–response manner (all p<0.05), with risk reductions between 40% and 60%. β‐carotene was also strongly and negatively associated with risk, particularly with the intestinal type. The associations with α‐tocopherol (vitamin E) were less clear. The highest parallel intake of all three antioxidants (quartiles 4), compared to those with the lowest parallel intakes (quartiles 1), was associated with a 70% lower risk of developing noncardia cancer (OR 0.3, 95% CI 0.1–0.9). Our results suggest that antioxidants might be especially beneficial among subjects at increased risk for gastric cancer such as smokers and those infected by H. pylori. We conclude that a high intake of antioxidants, as a consequence of high consumption of fruit and vegetables, may lower the risk not only for gastric cancer of the intestinal type, but also for diffuse type adenocarcinoma and cardia cancer. Int. J. Cancer 87:133–140, 2000. © 2000 Wiley‐Liss, Inc.
Person-Centered, Physical Activity for Patients with Low Back Pain: Piloting Service Delivery

Low back pain (LBP) is one of the most common and costly conditions in industrialized countries. Exercise therapy has been used to treat LBP, although typically using only one mode of exercise. This paper describes the method and initial findings of a person-centered, group physical activity programme which featured as part of a multidisciplinary approach to treating LBP. Six participants (aged 50.7 ± 17 years) completed a six-week physical activity programme lasting two hours per week. A multicomponent approach to physical activity was adopted which included aerobic fitness, core activation, muscular strength and endurance, Nordic Walking, flexibility and exercise gaming. In addition, participants were required to use diary sheets to record physical activity completed at home. Results revealed significant (p < 0.05) improvements in back strength (23%), aerobic fitness (23%), negative wellbeing (32%) and disability (16%). Person’s Correlation Coefficient analysis revealed significant (p < 0.05) relationships between improvement in perceived pain and aerobic fitness (r = 0.93). It was concluded that a person-centered, multicomponent approach to physical activity may be optimal for supporting patients who self-manage LBP.
Functional Outcome Following Surgical Excision of Heterotopic Ossification in Patients with Traumatic Brain Injury

Summary Increased osteogenesis, both in fracture healing and heterotopically, occurs in a significant percentage of patients with traumatic brain injury. Periarticular heterotopic ossification, especially in the hip and elbow joint, can cause functional loss of motion in patients with traumatic brain injury and interfere with activities of daily living. Seventeen patients with traumatic brain injury had periarticular heterotopic ossification resected in 20 joints (13 hips and seven elbows). Each joint was ankylosed prior to surgical resection (Brooker IV). In the immediate postoperative period, the average arc of motion was 85° in the hips and 65° in the elbows. At the final follow-up observation (average, 23 months), 17 of the 20 heterotopic ossification resected joints had maintained functional range of motion. Three joints in two patients reanky-losed. Two additional patients had significant complications. In summary, surgical excision of periarticular heterotopic ossification in patients with traumatic brain injury can give satisfactory results, provided appropriate preoperative selection is done.
Primary and multisensory cortical activity is correlated with audiovisual percepts

Incongruent auditory and visual stimuli can elicit audiovisual illusions such as the McGurk effect where visual /ka/ and auditory /pa/ fuse into another percept such as/ta/. In the present study, human brain activity was measured with adaptation functional magnetic resonance imaging to investigate which brain areas support such audiovisual illusions. Subjects viewed trains of four movies beginning with three congruent /pa/ stimuli to induce adaptation. The fourth stimulus could be (i) another congruent /pa/, (ii) a congruent /ka/, (iii) an incongruent stimulus that evokes the McGurk effect in susceptible individuals (lips /ka/ voice /pa/), or (iv) the converse combination that does not cause the McGurk effect (lips /pa/ voice/ ka/). This paradigm was predicted to show increased release from adaptation (i.e. stronger brain activation) when the fourth movie and the related percept was increasingly different from the three previous movies. A stimulus change in either the auditory or the visual stimulus from /pa/ to /ka/ (iii, iv) produced within‐modality and cross‐modal responses in primary auditory and visual areas. A greater release from adaptation was observed for incongruent non‐McGurk (iv) compared to incongruent McGurk (iii) trials. A network including the primary auditory and visual cortices, nonprimary auditory cortex, and several multisensory areas (superior temporal sulcus, intraparietal sulcus, insula, and pre‐central cortex) showed a correlation between perceiving the McGurk effect and the fMRI signal, suggesting that these areas support the audiovisual illusion. Hum Brain Mapp, 2010. © 2009 Wiley‐Liss, Inc.
Toxic and essential metals determination in commercial seafood: Paracentrotus lividus by ICP-MS

Toxic and essential metals content was determined by inductively coupled plasma mass spectrometry in commercial sea urchins samples from the Mediterranean Sea and Pacific Ocean. Results show that Chilean samples have the highest values of Cd, As, Ni, Cr and V; Spanish samples have the maximum Hg content while Sicilian samples have the lowest content of toxic metals. The toxic metal traces were compared with the limits of European Community (EC) No. 1881/2006 for bivalve molluscs. All samples exceed Pb and Cd limit levels; regarding Hg levels, only Sicilian and Sardinian samples have Hg content below the EC limits. The dietary intake of toxic and essential elements was evaluated for an adult. Furthermore, our study highlights a correlation between the toxic elements content and the marine environmental conditions of the places of origin even though only the generic FAO fishing area is specified.
Determination of acute and chronic effects of cadmium on the cardiovascular system of rats

In this study, the systemic hemodynamics induced by acute and chronic cadmium (Cd+2) intoxication in the cardiovascular system of rats using thoracic electrical bioimpedance were examined and the acute and chronic effects of Cd+2 intoxication on the activities of antioxidant enzymes and malondialdehyde (MDA) were compared. Also, in this study, ultrastructural changes in the heart and aorta of rats were evaluated. Thirty-eight male Wistar albino rats were randomly divided into control, acute, and chronic groups. Chronic group was administered by oral gavage an aqueous solution of CdCl2 for 60 days, at dose of 15 mg Cd+2/kg/day. Acute group was administered by oral gavage an aqueous solution of CdCl2 with a single dose of 15 mg Cd+2/kg. Cadmium increased the stroke volume and cardiac output of rats in the chronic group, but did not change the heart rate significantly. Antioxidant enzymes activities and MDA level significantly increased in the chronic group. In ultrastructural examination, there were widespread degenerative changes in heart muscle cells of the chronic group but endothelial cells and smooth muscle cells in the aorta tissue samples had normal morphological features in all groups. All of the findings indicate that Cd+2 toxication can cause deformation in heart muscle cells due to an increase in free radicals and lipid peroxidation. Also, this study has confirmed that a long-term-Cd+2 exposure increased stroke volume (SV) and cardiac output (CO), but did not change the heart rate (HR).
Culture‐Fair Behavioral Symptom Differential Assessment and Intervention in Dementing Illness

Ethnically diverse populations are not represented in the dementia-related noncognitive behavioral symptom research arena. Some of the obstacles are structural, centering around the lack of inclusion of ethnic minority groups within existing projects. These impediments are surmountable by the systematic targeting and incorporation of ethically diverse populations in research and the deployment of a variety of research-related outreach approaches. The more formidable barriers are conceptual. They relate to the need to differentiate cultural factors from socioeconomic and social status (SES) artifacts and to include life-long exposure to various forms of prejudice and discrimination, all of which can come together in the late-life manifestation of behavioral symptoms. A culture-fair behavioral assessment and intervention model is presented. It allows researcher and clinician alike access to ethnocultural data, while differentiating SES influences. A comparative Hispanic/Anglo dementia caregiver pilot study has provided a partial test of the model with statistically significant outcomes. Two-tailed t tests (p⩽0.05) uncovered ethnic group differences with respect to four specific dimensions of caregiving. The differences were demonstrated around reactivity to caregiving burden, caregiver health status, coping and helpseeking styles, and configuration of social support received from social network members. Further multiple regression analysis sustained the observed differences despite income, education, and mean age variance between the two ethnic groups. The model has an overall multicultural applied intent. More study is indicated.
Parents' Marital Status, Conflict, and Role Modeling: Links With Adult Romantic Relationship Quality

This study investigated three parental marital statuses and relationship quality among unmarried, but dating adults ages 18 to 35 (N = 1,153). Those whose parents never married one another tended to report the lowest relationship quality (in terms of relationship adjustment, negative communication, commitment, and physical aggression) compared to those with divorced or married biological parents. In addition, those with divorced parents reported lower relationship adjustment and more negative communication than those with married parents. Parental conflict and the degree to which participants rated their parents' relationship as a healthy model for their own relationships partially explained the associations between parental marital status and relationship outcomes. We suggest that this particular family type (i.e., having parents who never marry one another) needs greater attention in this field in terms of research and intervention.
Isolated posterior cruciate ligament injuries in athletes

The literature is divided as to the necessity of an intact posterior cruciate ligament for functional stability. Pre sented here is a prospective study of isolated posterior cruciate injuries seen in the acute stage in 13 patients, 6 males and 7 females. The diagnosis of posterior cruciate ligament tear was made clinically and con firmed by arthroscopy. The average age at injury was 22 years. The athletic activity at injury was varied. Hyperflexion was the most common mechanism of injury, followed by pretibial trauma in the hyperflexed knee or in the "dashboard" injury. There were seven complete midsubstance tears and five partial tears. Direct visualization of the posterior cruciate ligament was not attained in one patient. All patients were treated nonoperatively on a physiotherapy routine. Av erage followup was 2.6 years. Patients were clinically examined and subjected to KT-1000 and Cybex testing. All patients were able to return to their previous activity and experienced no limitations with their injured knees. Using Hughston's criteria, subjective and functional ratings were all good. However, only 3 rated good and 10 fair when assessed objectively. We conclude that acceptable functional stability in these patients does not necessarily require absolute static stability. Non- operative treatment of the isolated posterior cruciate ligament midsubstance injury may be a viable alterna tive to the difficult repair/reconstruction procedure.
Density of tobacco retailers near schools: effects on tobacco use among students.

OBJECTIVES We examined the relationship between students' tobacco use and the density and proximity of tobacco retailers near their schools. METHODS We used data from the 2003-2004 California Student Tobacco Survey and California retail licensing data. Measures included students' self-reported tobacco use and geocoded state-reported locations of tobacco retailers. We used random-intercept generalized linear mixed modeling to jointly evaluate individual-level and school-level predictors. RESULTS Density of retailers was associated with experimental smoking (odds ratio [OR] = 1.11; 95% confidence interval [CI] = 1.02, 1.21) but not established smoking (OR = 1.06; 95% CI = 0.94, 1.20). The effects on experimental smoking were confined to high school students (OR = 1.17; 95% CI = 1.06, 1.29) in urban areas (OR = 1.11; 95% CI = 1.01, 1.21); no effects were observed among middle school students or in rural schools. High school students were more likely to obtain cigarettes from a retailer; middle school students relied more heavily on social sources. CONCLUSIONS Our results support the plausibility of reducing rates of students' experimental smoking, but not established smoking, by restricting their access to commercial sources of tobacco in urban areas.
Infrared thermometry in the diagnosis of hand-arm vibration syndrome.

BACKGROUND Clinicians need an accurate diagnostic test for hand-arm vibration syndrome (HAVS). AIMS To validate a simple thermometric method to diagnose HAVS-related Raynaud's phenomenon. METHODS Fifteen workers with photographically confirmed HAVS-related Raynaud's phenomenon were compared to controls without Raynaud's phenomenon and an occupational history of hand-arm vibration exposure. Digit temperatures were measured using an infrared thermometer before and after immersion in 5 degrees C water for 1 min. RESULTS The HAVS patients differed significantly from the controls in terms of baseline temperature, rewarming time and rate. The fingertip-base temperature gradient was more commonly positive among the controls. CONCLUSIONS The test method evaluated in this study is simple, cheap and accurate. If the pre-test probability is at least 35%, the best test variable to confirm the diagnosis of HAVS-related Raynaud's phenomenon is the time to rewarm to baseline of the first three fingertips providing the interval is > or =8-9 min.