Miracle-dz/UniFAR-FTUs huggingface dataset:
Making the Transition: The Impact of Moving from Elementary to Secondary School on Adolescents' Academic Achievement and Psychological Adjustment

Early adolescence is a time of rapid social, cognitive, and physical change. For some youth, these changes can make this period a vulnerable point in development. Adding to the stress, some students transfer from an elementary school to a middle school or to a comprehensive high school. While the impact on youth of moving to a higher level of schooling has been the focus of intense research and debate in the United States, surprisingly little research has been conducted examining how Canadian youth make this transition within the context of Canadian schools. With this in mind, this paper examines the academic, behavioural and emotional adjustment of Canadian adolescents who transfer from an elementary school to a middle or comprehensive high school and compares their outcomes to those of a group of youth who did not change schools. Results of several statistical analyses suggest that changing schools had little systematic association to adolescents' academic outcomes. This held true regardless of whether the school was a middle school or a comprehensive high school. Similarly, transferring to a middle school had little negative association to adolescents' emotional and behavioural outcomes. Indeed, with respect to social aggression, the analyses suggested that students in middle schools may use indirect or socially directed aggression less frequently than students who remained in elementary school. However, transferring directly from an elementary school to a comprehensive high school appeared to have some negative emotional consequences. Youth who moved directly from an elementary school to a high school reported greater symptoms of physical stress. Further, female students who directly transfer to high schools at ages 12 and 13, reported higher levels of depressive affect than female adolescents who remained in an elementary school.
Reduction of exposure to laboratory animal allergens in a research laboratory.

OBJECTIVES The purpose of this study was to determine exposure levels in the laboratory during different tasks and evaluate the effectiveness of safety equipment used to reduce personal exposure. METHODS Personal and stationary air samples were collected during different tasks in a laboratory animal facility in which several allergen reduction strategies had been implemented. Mouse urinary allergen concentrations were measured using a polyclonal sandwich enzyme-linked immunosorbent assay. Sera from the personnel (n = 29) were analysed every 6 months for the presence of specific antibodies against mouse and rat urinary allergens, and the staff answered questionnaires on work-related symptoms, exposure and use of respiratory protection. RESULTS The highest airborne mouse allergen levels were measured during manual emptying of cages, during changing of cages on an unventilated table and during handling of male animals on an unventilated table. Automatic emptying and cleaning of cages resulted in low airborne allergen levels in the working room. Using a ventilated cage-changing wagon reduced the allergen exposure level from 77 to 17 ng/m3. The housing of animals in ventilated cabinets, with air exhausted through the cabinet, effectively prevented the release of allergens into the ambient air. The handling of animals on ventilated benches and the use of a centralized vacuum cleaner resulted in a low exposure level. Only two subjects developed specific immunoglobulin E of > 0.35 kU/l, of whom one was reduced to negative after increased use of respiratory protection. CONCLUSIONS Effective reduction of exposure to allergens can be achieved by several strategies, which together appear to minimize sensitization to rodents.
CF-Matter and the Cold Fusion Phenomenon*

The working concept of “cf-matter,” defined as “neutron drops in a thin neutron liquid” as described in previous papers, is used to explain complex events, especially nuclear transmutations, in cold fusion phenomenon (CFP). In samples used in CF experiments, the cf-matter contains high-density neutron drops in surface/boundary regions while in the volume it contains only a few of them, in accordance with experimental data. Generation of various nuclear transmutations, the most interesting features in CFP, are explained naturally if we use the concept of the cf-matter. Qualitative correspondence between the relative isotopic abundance of elements in the universe and the number of observations of elements in CFP is shown using more than 40 experimental data, sets. This facts is an evidence showing statistically that CFP in transition-metal hydrides/deuterides is a low energy version of nuclear processes occurring in the stars catalyzed by, specific neutrons in the cf-matter formed in surface/boundary regions of CF materials. 1. Abundance of Elements in the Universe 2. Formation of the cf-matter 3. Coulomb lattice in the cf-matter 4. Interaction of the cf-matter with extraneous nuclides in terms of experimental data 5. Production of New Nuclides in CFP 6. Relation of CFP Data with Abundances of the Elements 7. Discussion Acknowledgement References Papers used to count Nob in Table 4 Appendix “Solid State-Nuclear Physics of Cold Fusion Phenomenon”
Evaluation of a Tenant Level Checkpointing Technique for SaaS Applications

Tenant level check pointing is a novel fault-tolerance technique proposed in our previous work for large-scale software-as-a-service applications. This paper evaluates the technique by a theoretical analysis of the technique and an empirical study using workload benchmarks of real large-scale cluster systems. We propose the notion of accumulated delay as a measurement of the performance of check pointing techniques. It reflects the effect of check pointing on system performance as experienced by the end users. Both theoretical analysis and empirical study show that tenant level check pointing significantly outperforms traditional bulk check pointing as measured by the amount of accumulated delays.
The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding

The lineage factor Foxp3 is essential for the development and maintenance of regulatory T cells, but little is known about the mechanisms involved. Here, we demonstrate that an N-terminal proline-rich interaction region is crucial for Foxp3’s function. Subdomains within this key region link Foxp3 to several independent mechanisms of transcriptional regulation. Our study suggests that Foxp3, even in the absence of its DNA-binding forkhead domain, acts as a bridge between DNA-binding interaction partners and proteins with effector function permitting it to regulate a large number of genes. We show that, in one such mechanism, Foxp3 recruits class I histone deacetylases to the promoters of target genes, counteracting activation-induced histone acetylation and thereby suppressing their expression.
Volume loading augments cutaneous vasodilatation and cardiac output of heat stressed older adults

Age‐related changes in cutaneous microvascular and cardiac functions limit the extent of cutaneous vasodilatation and the increase in cardiac output that healthy older adults can achieve during passive heat stress. However, it is unclear if these age‐related changes in microvascular and cardiac functions maximally restrain the levels of cutaneous vasodilatation and cardiac output that healthy older adults can achieve during heat stress. We observed that rapid volume loading, performed during passive heat stress, augments both cutaneous vasodilatation and cardiac output in healthy older humans. These findings demonstrate that the microcirculation of healthy aged skin can further dilate during passive heat exposure, despite peripheral limitations to vasodilatation. Furthermore, healthy older humans can augment cardiac output when cardiac pre‐load is increased during heat stress.
Doing Leadership through Signswitching in the Indonesian Bureaucracy

In recent years the study of the relationship between talk and the doing of leadership has gained increasing attention from linguistic anthropologists and sociolinguists. Even so, as with much research on organizational talk, typically these studies focus on the micro analysis of situated talk in monolingual English-speaking settings. In this article I start to fill this gap by looking at how a boss moves between Indonesian and Javanese to do leadership. The empirical focus is on recordings of meetings made during five months of fieldwork in a government bureau in Semarang in 2003–2004. I show that while Indonesian is used to do much transactional work, Javanese does both relational and transactional work, often in ways that differ from earlier accounts of Javanese usage. In interpreting this usage I draw upon work on reciprocity to suggest that the use of Javanese fragments—along with other leadership practices—help build a locally emergent system of reciprocity.
Coronary Magnetic Resonance Angiography Using Magnetization-Prepared Contrast-Enhanced Breath-Hold Volume-Targeted Imaging (MPCE-VCATS)

Objectives:Coronary artery x-ray angiography (XRA) is currently the gold standard for the assessment of coronary artery disease. A substantial minority of patients referred for coronary angiography have no significant coronary artery disease. The purpose of this study is to evaluate magnetization-prepared contrast-enhanced breath-hold volume-targeted imaging (MPCE-VCATS), a new 3-dimensional breath-hold coronary magnetic resonance angiography (MRA) technique, in detecting hemodynamically significant coronary artery stenoses in a patient population, with XRA correlation. Materials and Methods:A total of 19 subjects who were referred for conventional coronary angiography were enrolled in the study. ECG-triggered MPCE-VCATS coronary artery scans were acquired for the left main coronary artery (LCA), left anterior descending (LAD), and right coronary artery (RCA). Coronary MRA and XRA results were compared. Results:The overall sensitivity, accuracy, and negative predictive value for diagnosing any hemodynamically significant coronary artery disease (≥50% diameter reduction) was 91%, 80%, and 90%, respectively. The sensitivity of the technique in the LCA, LAD, and RCA was 100%, 100% and 78%, respectively. The negative predictive value of the technique was 100%, 100%, and 71%, respectively. Discussion:MPCE-VCATS is a promising technique for coronary artery imaging. It has a relatively high sensitivity as well as a high NPV. The results of the study may indicate a future role for the technique in obviating the need for some patients to undergo XRA.
Humanistic Psychotherapies: Handbook of Research and Practice

A compendium of research and practice techniques in the field of humanistic psychotherapies. In addition to the editors' comprehensive overview of the history, defining characteristics and evolution of humanistic psychotherapies, the contributors illustrate significant research results in the last decades and document the effectiveness of major humanistic therapeutic approaches, including client-centred, Gestalt, existential and experiential. The research presented shows these approaches to be equivalent and, in many cases, superior to others in treating a wide range of psychopathology. Contributors also offer guidelines for practice and introduce innovative methods for working with an increasingly difficult, diverse and complex range of individuals, couples, families and groups. There are chapters focusing on empirical evidence from humanistic psychotherapeutic practice that demonstrate the importance of the psychotherapeutic relationship and therapist empathy in effecting successful client outcome. Also stressed is the effectiveness of humanistic psychotherapies in establishing methods for working with client emotion and enabling patients with severe disabilities such as schizophrenia to progress in their development and functioning.
ANÁLISIS MOTIVACIONAL COMPARATIVO EN TRES CONTEXTOS DE ACTIVIDAD FÍSICA

La realizacion de este trabajo fue posible gracias al proyecto de investigacion "Evaluacion y analisis comparativo de factores motivacionales relacionados con la adherencia a la practica en diferentes contextos fisico-deportivos: Educacion fisica, deporte de competicion y actividad fisica no competitiva" (Ref. DEP2007-73201-C03/ACTI), financiado por el Ministerio de Ciencia e Innovacion de Espana
Sodium Intake Alters the Effects of Norepinephrine on Blood Pressure

SUMMARY To examine the Interactions between sodium balance and the sympathetic nervous system, we studied eight normotensive men after high (800 mEq/day) and low (10 mEq/day) sodium intake. We measured blood pressure (BP), arterial, venous, and urinary norepinepfarine (NE) before and during incremental infusion of NE. We found significant direct, linear relationships (p < 0.001) between the dose of NE infused and arterial and venous NE levels, and with mean arterial BP at both levels of sodium balance. In addition, the sensitivity was greater and the threshold of pressor response to NE as well as the basal concentrations of NE in arterial and venous plasma significantly lower (p < 0.05) after the high sodium period. These observations expose heretofore unrecognized qualitative and quantitative interactions between sodium balance and NE that are capable of influencing BP in man.
The Female Genital Self-Image Scale (FGSIS): results from a nationally representative probability sample of women in the United States.

INTRODUCTION Over the past two decades, an expanding body of research has examined women's and men's genital self-image. Support for the reliability and validity of the 7-item Female Genital Self-Image Scale (FGSIS) has been found in a convenience sample of women. AIMS The purpose of this study was to assess the reliability and validity of the FGSIS, its model of fit, and its association with women's scores on the Female Sexual Function Index (FSFI) in a nationally representative probability sample of women in the United States ages 18 to 60. A second purpose was to assess the temporal stability of the scale in a subset of this sample. METHODS A nationally representative sample of 3,800 women ages 18 to 60 were invited to participate in a cross-sectional Internet-based survey; 2,056 (54.1%) participated. MAIN OUTCOME MEASURES Demographic items (e.g., age, race/ethnicity, marital status, sexual orientation, geographic region), having had a gynecological examination in the past year, having performed a genital self-examination in the past month, frequency of masturbation in the past month, vibrator use in the past month, the FGSIS, and the FSFI. RESULTS An abbreviated 4-item version of the scale, the FGSIS-4, was a better fit to the data than the original 7-item scale. Women's scores on the FGSIS-4 were significantly related to vibrator use, frequency of masturbation, having had a gynecological exam in the past year, having performed genital self examination in the past month, and all FSFI subscales. CONCLUSION Most of the participants felt generally positively about their genitals and female genital self-image was significantly related to female sexual function, women's sexual behavior and their sexual and genital healthcare behaviors. In addition, the FGSIS-4 has evidence of reliability, validity, and temporal stability in a nationally representative probability sample of women in the United States.
Melatonin‐related genes expressed in the mouse uterus during early gestation promote embryo implantation

Melatonin, a superior antioxidant, is an important molecule which regulates female reproduction due to its receptor‐mediated and receptor‐independent antioxidant actions. In this study, we investigated the effect of melatonin on early gestation in a mouse model. During early gestation, the expression of the melatonin's rate‐limiting enzyme, AANAT, gradually increased – in the uterus while the MT2 melatonin receptor was only expressed at day 2 of gestation and no MT1 was detected. Based on these findings, we conducted a melatonin injection experiment which demonstrated that 15 mg/kg melatonin significantly improved the number of implantation sites and the litter size. Also, the blastocyst and uterus were collected to identify the local action of melatonin. In the melatonin‐treated mice, the endometrium was thicker than in the control mice; melatonin also caused an increase in density of uterine glands, and the uterine gland index (UGI) was significantly elevated over that of the control. Serum steroid hormone measurements revealed that at day 6 of gestation (postimplantation), melatonin significantly downregulated the E2 level, with no obvious effects on progesterone. Gene expression assay revealed that melatonin significantly upregulated expression of HB‐EGF, a crucial gene involved in implantation as well as its receptor ErbB1 in the blastocyst. In addition, PRA, an important gene which influences the decidual response and luminal cell differentiation, p53, which regulates uterine through leukaemia inhibitory factor (LIF), were both increased after melatonin treatment. These data suggest that melatonin and its MT2 receptor influence early gestation. Exogenous melatonin treatment can improve mouse embryo implantation and litter size, which may have important applications in human reproductive health and animal husbandry.
Reducing diarrhoea in Guatemalan children: randomized controlled trial of flocculant-disinfectant for drinking-water.

OBJECTIVE To examine the effect of a new point-of-use treatment for drinking-water, a commercially developed flocculant-disinfectant, on the prevalence of diarrhoea in children. METHODS We conducted a randomized controlled trial among 514 rural Guatemalan households, divided into 42 neighbourhood clusters, for 13 weeks, from 4 November 2002 through 31 January 2003. Clusters assigned to water treatment with the flocculant-disinfectant were compared with those using their usual water-handling practices. The longitudinal prevalence of diarrhoea was calculated as the proportion of total days with diarrhoea divided by the total number of days of observation. The prevalence of diarrhoea was compared using the Wilcoxon rank-sum test. FINDINGS The 1702 people in households receiving the disinfectant had a prevalence of diarrhoea that was 40% lower than that among the 1699 people using standard water-handling practices (0.9% versus 1.5%; P = 0.001). In households using the flocculant-disinfectant, children < 1 year of age had a 39% lower prevalence of diarrhoea than those in households using their standard practices (3.7% versus 6.0%; P = 0.005). CONCLUSION In settings where families rarely treat drinking-water, we introduced a novel flocculant-disinfectant that reduced the longitudinal prevalence of diarrhoea, especially among children aged < 1 year, among whom diarrhoea has been strongly associated with mortality. Successful introduction and use of this product could contribute to preventing diarrhoeal disease globally.
RIGID-FOLDABLE CYLINDERS AND CELLS

In this paper, we present newly explored families of rigid-foldable cylinders and the cellular structures constructed from these cylinders; the families include zonogon extrusion cells, bi-directionally flat-foldable cells, and a novel type of cells, i.e., woven cylinder cells. We show the geometry of such structures to demonstrate their validity, their parametric design method, and their kinetic behaviors. These types of structures exhibit continuous rigid-foldability as well as flat-foldability in one or two directions; further, they have different kinetic properties that are potentially applicable for different purposes. The newly proposed woven cylinder cellular structure is a bi-directionally flat-foldable one-DOF rigid-foldable structure and has a distinctive geometric property: structural stiffness against compression in one of three directions.
Schizophrenia across the world: outcome and recovery

the International Pilot study of schizophrenia (IPss) was a seminal, ground-breaking study that revealed important information regarding schizophrenia on a global scale. Perhaps the most interesting and controversial finding was that for all outcome variables considered, patients suffering from schizophrenia in nigeria and India (‘developing countries’) tended to ‘recover’ better than patients in the other six sites. however, in recent times, this finding has been repeatedly challenged. the renewed debate led to a vigorous rebuttal by some of the original IPss study authors. In an increasingly globalised world, the IPss stands as a reminder of the importance of the cultural determinants of recovery from schizophrenia.
Barriers to Adult Learning: Bridging the Gap.

A fundamental aspect of adult education is engaging adults in becoming lifelong learners. More often than not, this requires removing barriers to learning, especially those relating to the actual organisational or institutional learning process. This article explores some of the main barriers to adult learning discussed in the literature and examines some practical guidance on how to overcome them.
Complex I within Oxidatively Stressed Bovine Heart Mitochondria Is Glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit

Complex I has reactive thiols on its surface that interact with the mitochondrial glutathione pool and are implicated in oxidative damage in many pathologies. However, the Cys residues and the thiol modifications involved are not known. Here we investigate complex I thiol modification within oxidatively stressed mammalian mitochondria, containing physiological levels of glutathione and glutaredoxin 2. In mitochondria incubated with the thiol oxidant diamide, complex I is only glutathionylated on the 75-kDa subunit. Of the 17 Cys residues on the 75-kDa subunit, 6 are not involved in iron-sulfur centers, making them plausible candidates for glutathionylation. Mass spectrometry of complex I from oxidatively stressed bovine heart mitochondria showed that only Cys-531 and Cys-704 were glutathionylated. The other four non-iron-sulfur center Cys residues remained as free thiols. Complex I glutathionylation also occurred in response to relatively mild oxidative stress caused by increased superoxide production from the respiratory chain. Although complex I glutathionylation within oxidatively stressed mitochondria correlated with loss of activity, it did not increase superoxide formation, and reversal of glutathionylation did not restore complex I activity. Comparison with the known structure of the 75-kDa ortholog Nqo3 from Thermus thermophilus complex I suggested that Cys-531 and Cys-704 are on the surface of mammalian complex I, exposed to the mitochondrial glutathione pool. These findings suggest that Cys-531 and Cys-704 may be important in preventing oxidative damage to complex I by reacting with free radicals and other damaging species, with subsequent glutathionylation recycling the thiyl radicals and sulfenic acids formed on the Cys residues back to free thiols.