Miracle-dz/UniFAR-FTUs huggingface dataset:
Adding Collaborative Peer Coaching to Our Teaching Identities

Recent research suggests that personal and institutional constraints often limit the degree to which professional development impacts teaching practice. Darling-Hammond suggests that one of those constraints is time in schools for collaborative planning. She cites high performing schools in Europe and Asia that have three to four times more collaborative planning time for teachers than schools in the United States, and she suggests that teachers need to discover ways to collaborate to solve problems and improve practice. One way to create the kinds of collaborative teaching communities that Darling-Hammond proposes is with peer coaching, and this article describes a group of teachers who found ways to work and learn together by adding collaborative peer coaching to their identities as teachers.
Control of Directionality in Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination

Streptomyces phage φBT1 integrates its genome into the attB site of the host chromosome with the attP site to generate attL and attR. The φBT1 integrase belongs to the large serine recombinase subfamily which directly binds to target sites to initiate double strand breakage and exchange. A recombination directionality factor (RDF) is commonly required for switching integration to excision. Here we report the characterization of the RDF protein for φBT1 recombination. The RDF, is a phage-encoded gp3 gene product (28 KDa), which allows efficient active excision between attL and attR, and inhibits integration between attB and attP; Gp3 can also catalyze topological relaxation with the integrase of supercoiled plasmids containing a single excision site. Further study showed that Gp3 could form a dimer and interact with the integrase whether it bound to the substrate or not. The synapse formation of attL or attR alone with integrase and Gp3 showed that synapsis did not discriminate between the two sites, indicating that complementarity of central dinucleotides is the sole determinant of outcome in correct excision synapses. Furthermore, both in vitro and in vivo evidence support that the RDFs of φBT1 and φC31 were fully exchangeable, despite the low amino acid sequence identity of the two integrases.
Branch and Cut and Price for the Pickup and Delivery Problem with Time Windows

In the pickup and delivery problem with time windows vehicle routes must be designed to satisfy a set of transportation requests, each involving a pickup and delivery location, under capacity, time window, and precedence constraints. This paper introduces a new branch-and-cut-and-price algorithm in which lower bounds are computed by solving through column generation the linear programming relaxation of a set partitioning formulation. Two pricing subproblems are considered in the column generation algorithm: an elementary and nonelementary shortest path problem. Valid inequalities are added dynamically to strengthen the relaxations. Some of the previously proposed inequalities for the pickup and delivery problem with time windows are also shown to be implied by the set partitioning formulation. Computational experiments indicate that the proposed algorithm outperforms a recent branch-and-cut algorithm.
Simulium (Simulium) lomkaoense, a New Species of Black Fly (Diptera: Simuliidae) from Thailand

ABSTRACT Simulium (Simulium) lomkaoense sp. nov. is described from females, males, pupae, and larvae in Thailand. This new species is assigned to the Simulium malyschevi Dorogostaisky, Rubtsov & Vlasenko species-group of the subgenus Simulium, and appears to be closely related to Simulium baimaii Kuvangkadilok & Takaoka from Thailand in having a similar shape of the female and male genitalia, pupal gill with two inflated filaments, and simple wall-pocket-shaped cocoon. This new species is compared taxonomically with S. baimaii and other related species. It represents the third species of the S. malyschevi species-group known from Thailand.
Effects of a Structured Exercise Program on Physical Activity and Fitness in Colon Cancer Survivors: One Year Feasibility Results from the CHALLENGE Trial

Background: There is strong interest in testing lifestyle interventions to improve cancer outcomes; however, the optimal methods for achieving behavior change in large-scale pragmatic trials are unknown. Here, we report the 1-year feasibility results for exercise behavior change in the Canadian Cancer Trials Group CO.21 (CHALLENGE) Trial. Methods: Between 2009 and 2014, 273 high-risk stage II and III colon cancer survivors from 42 centers in Canada and Australia were randomized to a structured exercise program (SEP; n = 136) or health education materials (HEM; n = 137). The primary feasibility outcome in a prespecified interim analysis was a difference between randomized groups of ≥5 metabolic equivalent task (MET)-hours/week in self-reported recreational physical activity (PA) after at least 250 participants reached the 1-year follow-up. Secondary outcomes included health-related fitness. Results: The SEP group reported an increase in recreational PA of 15.6 MET-hours/week compared with 5.1 MET-hours/week in the HEM group [mean difference = +10.5; 95% confidence interval (CI) = +3.1–+17.9; P = 0.002]. The SEP group also improved relative to the HEM group in predicted VO2max (P = 0.068), 6-minute walk (P < 0.001), 30-second chair stand (P < 0.001), 8-foot up-and-go (P = 0.004), and sit-and-reach (P = 0.08). Conclusions: The behavior change intervention in the CHALLENGE Trial produced a substantial increase in self-reported recreational PA that met the feasibility criterion for trial continuation, resulted in objective fitness improvements, and is consistent with the amount of PA associated with improved colon cancer outcomes in observational studies. Impact: The CHALLENGE Trial is poised to determine the causal effects of PA on colon cancer outcomes. Cancer Epidemiol Biomarkers Prev; 25(6); 969–77. ©2016 AACR.
Characteristics of Idiosyncratic Drug-induced Liver Injury in Children: Results From the DILIN Prospective Study

Background: The spectrum and severity of idiosyncratic drug-induced liver injury (DILI) in children are not well established. Patients and Methods: The DILIN (Drug-Induced Liver Injury Network) Prospective Study is a longitudinal multicenter study designed to determine the etiologies, risk factors, and outcomes of suspected DILI. Between September 2004 and September 2009, 30 children ages 2 to 18 years with suspected DILI who met eligibility criteria were enrolled and studied for at least 6 months. Results: Mean age was 14 years; 70% were girls. Antimicrobial (50%) and central nervous system agents (40%) were the most commonly implicated drug classes, with minocycline (4), isoniazid (3), azithromycin (3), atomoxetine (3), and lamotrigine (3) the leading agents. Median time from drug initiation to symptom onset was 32 days. Peak (median) liver chemistries were aspartate aminotransferase 503 U/L, alanine aminotransferase 727 U/L, alkaline phosphatase 331 U/L, and total bilirubin 3.9 mg/dL. Autoantibodies were common (64%). Liver injury pattern was hepatocellular 78%, cholestatic 13%, and mixed 9%. The DILI episode was scored: mild 32%, moderate 44%, severe 20%, and fatal (within 6 months) 4%. Causality assessment was definite 36%, very likely 36%, probable 16%, possible 8%, and unlikely 4%. Seven percent had persistent liver test abnormalities at 6-month follow-up suggesting chronic DILI. Liver biopsies from 12 children most frequently demonstrated chronic hepatitis or bile duct injury. Conclusions: Idiosyncratic DILI in children is most commonly caused by antimicrobial or central nervous system agents and usually presents with a hepatocellular injury pattern. The majority of patients recover, but morbidity and infrequent mortality are seen.
Probing Newton's constant on vast scales: Dvali-Gabadadze-Porrati gravity, cosmic acceleration, and large scale structure

The nature of the fuel that drives today’s cosmic acceleration is an open and tantalizing mystery. The braneworld theory of Dvali, Gabadadze, and Porrati (DGP) provides a context where late-time acceleration is driven not by some energy-momentum component (dark energy), but rather is the manifestation of the excruciatingly slow leakage of gravity off our four-dimensional world into an extra dimension. At the same time, DGP gravity alters the gravitational force law in a specific and dramatic way at cosmologically accessible scales. We derive the DGP gravitational force law in a cosmological setting for spherical perturbations at subhorizon scales and compute the growth of large-scale structure. We find that a residual repulsive force at large distances gives rise to a suppression of the growth of density and velocity perturbations. Explaining the cosmic acceleration in this framework leads to a present day fluctuation power spectrum normalization �8 ≤ 0.8 at about the two-sigma level, in contrast with observations. We discuss further theoretical work necessary to go beyond our approximations to confirm these results.
Impact of group on the evacuation process: theory and simulation

Our main purpose is to build a simulation describing the persons movements in a public area during a crisis situation. Our running example is about the evacuation process of a supermarket during a fire. The main difficulty of such works comes from the fact that it is generally impossible to obtain precise descriptions of persons behaviors. After several works on individual emotions we are convinced that emotion is well adapted to explain such actions in a situation crisis. In the aim to test our hypothesis, we present here a first simulation (without any emotion management) that is a first step of our main purpose. This simulation aims to describe the well-known fact that, in crisis situation, humans tend toward to help each others. Thus, we test the impact of group constitution on survival rate and on average time. The simulation has been implemented with the platform GAMA.
The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA

Multiple myeloma, the second most frequent hematologic tumor after lymphomas, is an incurable cancer. Recent sequencing efforts have identified the ribonuclease DIS3 as one of the most frequently mutated genes in this disease. DIS3 represents the catalytic subunit of the exosome, a macromolecular complex central to the processing, maturation and surveillance of various RNAs. miRNAs are an evolutionarily conserved class of small noncoding RNAs, regulating gene expression at post-transcriptional level. Ribonucleases, including Drosha, Dicer and XRN2, are involved in the processing and stability of miRNAs. However, the role of DIS3 on the regulation of miRNAs remains largely unknown. Here we found that DIS3 regulates the levels of the tumor suppressor let-7 miRNAs without affecting other miRNA families. DIS3 facilitates the maturation of let-7 miRNAs by reducing in the cytoplasm the RNA stability of the pluripotency factor LIN28B, a inhibitor of let-7 processing. DIS3 inactivation, through the increase of LIN28B and the reduction of mature let-7, enhances the translation of let-7 targets such as MYC and RAS leading to enhanced tumorigenesis. Our study establishes that the ribonuclease DIS3, targeting LIN28B, sustains the maturation of let-7 miRNAs and suggests the increased translation of critical oncogenes as one of the biological outcomes of DIS3 inactivation.
Social Interaction Behavior in ADHD in Adults in a Virtual Trust Game

Objective: Social cognitive functions in adults with ADHD were investigated in a virtual social exchange game. Method: The sample consisted of 40 participants (20 adult ADHD participants, 20 healthy controls). Participants played a multiround trust game with virtual trustees who differed in regard to fairness and presence of emotional facial cues. Results: Investments were higher in ADHD participants than in healthy participants except for partners who played fair with constant neutral expressions. ADHD patients did not adapt their behavior to the fairness of the trustee. In the presence of emotional facial cues, ADHD and healthy participants transferred more monetary units to happy rather than angry-looking trustees. Differences in investment behavior were not linked to deficits in emotion-recognition abilities or cognitive dysfunctions. Conclusion: Alterations in interaction behavior and in the formation of a general attitude toward social partners could be shown in adults with ADHD.
Battered Women In The Courtroom: The Power of Judicial Responses

Recent laws have given women much-needed rights in seeking protection from abusive men, but judges still hold the authority to issue restraining orders or send batterers to jail. While most studies on state intervention for victims have focused on the role of police, Battered Women in the Courtroom looks at the lives of abused women. This investigation of women, violence, and the courts centers on encounters between women and judges in restraining order hearings in Massachusetts, one of the first states to offer new civil and criminal options to victims of abusive behavior. It also examines the feminist political movements that gave rise to current state laws and considers the effects of men's violence on women's daily lives. James Ptacek questions whether judges still respond to abused women with indifference or impatience, as they have in the past, or whether they now treat battering as a serious crime. He looks at the types of violence that women report to the courts, analyzes how judges exercise their authority in restraining order hearings, examines how they perceive their role in negotiations with women, and studies their impact on women's efforts to escape the social entrapment of violence. The author also considers class and racial dimensions of the issue by drawing on cases from both white and African American communities. Ptacek exposes many of the myths and dilemmas about the abuse of women while addressing the political, institutional, and socio-psychological aspects of women's experiences with the courts. He offers crucial insights into the power of judges to encourage or discourage women from claiming their rights under the law.
A Note on the Period Enforcer Algorithm for Self-Suspending Tasks

The period enforcer algorithm for self-suspending real-time tasks is a technique for suppressing the "back-to-back" scheduling penalty associated with deferred execution. Originally proposed in 1991, the algorithm has attracted renewed interest in recent years. This note revisits the algorithm in the light of recent developments in the analysis of self-suspending tasks, carefully re-examines and explains its underlying assumptions and limitations, and points out three observations that have not been made in the literature to date: (i) period enforcement is not strictly superior (compared to the base case without enforcement) as it can cause deadline misses in self-suspending task sets that are schedulable without enforcement; (ii) to match the assumptions underlying the analysis of the period enforcer, a schedulability analysis of self-suspending tasks subject to period enforcement requires a task set transformation for which no solution is known in the general case, and which is subject to exponential time complexity (with current techniques) in the limited case of a single self-suspending task; and (iii) the period enforcer algorithm is incompatible with all existing analyses of suspension-based locking protocols, and can in fact cause ever-increasing suspension times until a deadline is missed.
Plausible Explanations and Instance–Based Learning in Mixed Symbolic/Numeric Domains

The paper is concerned with supervised learning of numeric target concepts. The task is to learn to predict or determine the exact values of some numeric target variables. Training examples may be described by both symbolic and numeric predicates. General domain knowledge may be available in qualitative form. The paper presents a general learning model for such domains. The model integrates a symbolic learning component, which is based on a multi–instance plausible explanation algorithm, and an instance– based learning component, which stores instances with precise values and predicts new values by interpolation. The symbolic component can use available qualitative background knowledge; it learns sub–concepts that partition the space for the underlying instance–based method. A realization of the model in a system named IBL–Smart is then described. The system has been applied to a complex task from the domain of tonal music, and some experimental results are reported that demonstrate the effectiveness of the method.
The Effects of Expectancies and Actual Communication on Nonverbal Adaptation and Communication Outcomes: A Test of Interaction Adaptation Theory.

Guided by interaction adaptation theory, this work continues a tradition of examining the relative effects of cognitive expectancies and actual communication behavior on communication outcomes. Communication relevant expectancies (pleasant versus unpleasant communication) and actual communication (high versus low involvement) were manipulated in the current experiment. Communication was a strong predictor of emotional experiences and evaluations of the communicator, and was also the most predictive of the adaptation behavior of the participants: pleasant behavior was consistently met with pleasant behavior, while unpleasant behavior was met with reciprocated kinesic involvement and with maintenance of other measures of pleasantness and expressiveness. Expectancies did independently influence observers’ perceptions of the participants’ behavior, with those expecting pleasant communication being perceived as behaving in a more expected manner than those expecting unpleasant communication. Additionally, part.
The Kounis-Zavras Syndrome with the Samter-Beer Triad

We present a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma, or the Samter-Beer triad of asthma, nasal polyps, and aspirin allergy. The Kounis-Zavras syndrome, also known as Kounis syndrome, leads to angina pectoris or acute coronary syndrome secondary to coronary vasospasm in response to an allergic stimulus, leading to mast-cell degranulation of vasospastic mediators. The vasospasm can result in myocardial infarction, as it did in our patient.
Point‐wise estimation of non‐linear effects of airborne pollen levels on asthma emergency room admissions

Airborne pollen levels have been associated with an increase in asthma morbidity (1). This relationship has usually been formulated in terms of a linear form. However, effects of environmental exposures on health could also be nonlinear (2). Approximations based on linear modals present limitations making arbitrary assumptions about shape of the relationship; also, categorical analyses usually have low efficiency and cut-off points are in most cases opportunistic (3). To solve these limitations, a nonparametric method to compute point-wise estimation of non-linear exposures has recently been proposed (4). Under a Generalized Additive Model (GAM) a nonparametric estimate of the relative risk (RR) can be defined as RRðx; xrefÞ 1⁄4 exp f ðxÞ f ðxrefÞ ð Þ, where xref is the reference value of the continuous exposure and f(x) any of usual smoothers. Asymptotic variance of ln(RR(x,xref)) can be expressed in terms of the covariance matrix of the smoother f(x) as
Effects of Gender Role Identity and Experience on Computer Attitude Components

The effects of prior experience and gender stereotyping upon the computer anxiety, confidence and liking of 144 male and female students who had just commenced their studies at university were examined. Males were found to have lower computer anxiety, higher confidence and greater liking than females. When the effects of prior experience and gender stereotyping were removed however, no significant sex difference on these measures remained. The pattern of associations between experience, gender stereotyping variables and computer attitude measures differed for males and females. Greater experience at home was associated with lower anxiety for both sexes, with higher confidence for males and with greater liking for females. The influence of other family members also differed for the two sexes. The attitudes of both males and females were more positive if they had a brother who used computers, but the influence of father's use was positive for males only, while the influence of mother's use was positive for females only. For females but not males, higher scores on the Masculinity scale of the Bern Sex Role Inventory were associated with more positive computer attitudes. The results demonstrate the importance of experience, particularly in a home context, and of gender stereotyping in determining how males and females perceive computers.
Comparing the Perceived Value of Information and Entertainment Mobile Services

The importance of perceived value in customer decision making is well known. However, few studies assess empirically the direct effects of various perceived value dimensions on post-purchase behavior. This article examines differences between information and entertainment mobile content service users in how their value perceptions influence intentions to repurchase, intentions to spread positive word of mouth, and willingness to pay a price premium. The direct effects of four value dimensions are analyzed: monetary, convenience, emotional, and social value. Within this study we also propose and test the antecedent effects of conditional and epistemic value. This approach advances the value literature through increasing our understanding of how individual value dimensions influence post-purchase behavior and of the role of epistemic and conditional value. Using a sample of 579 mobile service users, results are analyzed with multi-group structural equation modeling. The findings support use of multidimensional value and loyalty constructs to identify differences between service user groups, and argue for the use of differentiated value-based marketing strategies for entertainment and information mobile services. © 2008 Wiley Periodicals, Inc.
Extension Educational Needs Assessment of Women Farmers in South-South Nigeria

This paper highlights extension educational needs of women farmers in south-south Nigeria. It is argued that women are responsible for generating food security for their families in developing countries. Thus, women farmers, there is need to devise educational strategy to enhance their contribution to agriculture and rural development. With a multi-stage sampling technique, a total of 300 women farmers were selected for the surveywhich primary data were obtained through questionnaires. Descriptive statistics such as simple frequencies and percentages were used to analyzed the results. Recommendations were made that women farmers should be taken seriously as their men counterparts, extension should focus more attention on women and multiple format be adopted to present extension educational materials to women farmers.