Miracle-dz/UniFAR-FTUs huggingface dataset:
Discovering the flight autostabilizer of fruit flies by inducing aerial stumbles

Just as the Wright brothers implemented controls to achieve stable airplane flight, flying insects have evolved behavioral strategies that ensure recovery from flight disturbances. Pioneering studies performed on tethered and dissected insects demonstrate that the sensory, neurological, and musculoskeletal systems play important roles in flight control. Such studies, however, cannot produce an integrative model of insect flight stability because they do not incorporate the interaction of these systems with free-flight aerodynamics. We directly investigate control and stability through the application of torque impulses to freely flying fruit flies (Drosophila melanogaster) and measurement of their behavioral response. High-speed video and a new motion tracking method capture the aerial “stumble,” and we discover that flies respond to gentle disturbances by accurately returning to their original orientation. These insects take advantage of a stabilizing aerodynamic influence and active torque generation to recover their heading to within 2° in < 60 ms. To explain this recovery behavior, we form a feedback control model that includes the fly’s ability to sense body rotations, process this information, and actuate the wing motions that generate corrective aerodynamic torque. Thus, like early man-made aircraft and modern fighter jets, the fruit fly employs an automatic stabilization scheme that reacts to short time-scale disturbances.
Investigation on Furan Levels in Pressure-Cooked Foods

Furan is a food processing contaminant classified as possibly carcinogenic to humans. As the occurrence of furan has been reported in a variety of foods processed in sealed containers, the objective of this work was to investigate if the contaminant can be found in home-cooked foods prepared in a pressure cooker. For that, several foods including beans, soy beans, whole rice, beef, pork, potato, and cassava were pressure-cooked and analyzed for the furan content by gas chromatography coupled to mass spectrometry preceded by a headspace solid phase microextraction (HS-SPME-GC/MS). Furan was not found above the limit of quantification in the pressure-cooked samples. No furan has either been found in reheated samples after 24 hours under cold storage. Although levels up to 173 μg/kg were already reported for commercial canned/jarred foods, it seems that the cooking in a pressure cooker may not represent a concern in relation to the occurrence of furan in foods.
Civil Service Mandated Cutoff Scores: Challenges and Practice Recommendations

Los Angeles County's civil service rule specifies a 70% cutoff score regardless of the situation (type of job, type of assessment, or outcome of interest). This civil service rule would be difficult to defend if it were challenged in court, and the rule places the county at increased risk in the event of employment litigation, particularly with public safety jobs (police, fire, sheriff, etc.). Additionally, it is unlikely that this cutoff would optimally balance the county's interests in fair employment practices and expected job performance (SIOP, 2003). Given the propensity for public safety candidates and employees to file lawsuits related to hiring and promotions, and given the fact that public safety agencies in this county have been subjected to a number of employment-related lawsuits in the past, the current rule is problematic. Prior to this rule's development, as well as after its implementation in 1988, there has been substantial litigation related to cutoff scores, and courts have identified what they consider to be more and less appropriate methods for setting cutoff scores.
Clinical Characteristics and Treatment Options of Infantile Vascular Anomalies

AbstractTo analyze the clinical characteristics and treatment outcomes of vascular anomalies, and determine which therapy is safe and effective.The data of vascular anomalies pediatric patients who arrived at Beijing children's Hospital from January 2001 to December 2014 were analyzed retrospectively, including the influence of gender, age, clinical manifestation, diagnosis, treatment options, and outcomes. As to infantile hemangiomas, the outcomes of different treatments and their adverse reactions were compared. As to spider angioma and cutaneous capillary malformation, the treatment effect of 595 nm pulsed dye laser (PDL) is analyzed.A total number of 6459 cases of vascular anomalies were reclassified according to the 2014 ISSVA classification system. Among them, the gender ratio is 1:1.69, head-and-neck involved is 53.3%, the onset age within the first month is 72.4%, the age of initial encounter that younger than 6 months is 60.1%. The most common anomalies were infantile hemangiomas (42.6%), congenital hemangiomas (14.1%), and capillary malformations (29.9%). In treating infantile hemangiomas, laser shows the lowest adverse reactions rate significantly. Propranolol shows a higher improvement rate than laser, glucocorticoids, glucocorticoids plus laser, and shows no significant difference with propranolol plus laser both in improvement rate and adverse reactions rate. The total improvement rate of 595 nm PDL is 89.8% in treating spider angioma and 46.7% in treating cutaneous capillary malformation. The improvement rate and excellent rate of laser in treating cutaneous capillary malformation are growing synchronously by increasing the treatment times, and shows no significant difference among different parts of lesion that located in a body.Vascular anomalies possess a female predominance, and are mostly occurred in faces. Definite diagnosis is very important before treatment. In treating infantile hemangioma, propranolol is recommended as the first-line agent, and systemic use glucocorticoids should be considered when associated with serious complications. The 595 nm PDL is effective in managing superficial vascular malformations in childhood, and could attempt to increase the treatment times to improve the outcomes.
Perceived Barriers to Weight loss Programs for Overweight or Obese Women.

BACKGROUND In order to develop appropriate obesity control and treatment strategies, the key point is to understand the barriers perceived by overweight or obese people in trying to follow weight-loss programs. This study examined perceived barriers to weight-loss programs among overweight or obese women. METHODS In this descriptive-analytical study, 204 overweight or obese women aged 31.97± 10.62 yr, were selected randomly from the nutritional counseling centers in 2008 in Tabriz, Iran. The mean BMI was 33.83 ±5.75 kg/ m2. A structured questionnaire including questions on barriers to weight-loss diet and physical activity was filled out for each participant by face-to-face interview. Height and weight measured objectively and demographic details were obtained. Data analysis carried out using multiple regression and factor analysis. RESULTS The most important perceived barriers to weight-loss diets were 'situational barriers', stress, depression, and food craving. High educational level was independent determinant of situational barriers (β=0.329, P=0.048). Employee women had a higher mean score on stress and depression than students and housewives. Lack of time and exercising lonely were the most important items of "External barriers" and Lack of motivation was the most important item of "internal barriers" to physical activity. Employment and being student were highly associated with external barriers (β=1.018, P<0.001 and β=0.541, P= 0.002). Moreover, older women who had low educational level, perceived more internal barriers. CONCLUSION Weight reducing strategies should take into account the specific perceived barriers to weight-loss diets faced by overweight or obese women, particularly situational barriers, stress and depression and food craving; and lack of time and lack of motivation as barriers to physical activity.
A Comparison of the Effects of Dominance on Evolutionary Programming and Genetic Algorithms

Genetic Algorithms (GA) and Evolutionary Programming(EP) are both search techniques predicated upon simulating some of the processes outlined in evolutionary theories. Both techniques claim the capacity to find global minima (or alternately maxima) in large search spaces. Genetic Algorithms employ sexual reproduction among fit parents using genotypic operators such as crossover, bit mutation, and inversion. On the other hand, Evolutionary Programming espouses a form of asexual phenotypic reproduction whereby each candidate parent undergoes a zero-mean Gaussian mutation. Previous studies have shown that EP is capable of producing more precise solutions than GAs for a number of simple functions. This paper investigates another class of problem spaces for which GA outperforms EP, specifically problems where portions of a given solution have a greatly varying impact on the overall score. A simple representative problem is tested against typical EP and GA implementations with special attention paid to testing the effects of search parameters on both EP and GA performance. Finally, the relative performance and ease of use of the two paradigms is compared.
Qualitative Research: A Grounded Theory Example and Evaluation Criteria

The qualitative research paradigm, although occasionally applied, is not widely discussed in agribusiness and agricultural economics literature. The primary goals of this paper are (a) to present insights into qualitative research approaches and processes by outlining grounded theory as an example of a systematic and rigorous qualitative approach, and (b) to discuss criteria for scientific rigor applicable to qualitative research. In addition, assessing qualitative research is demonstrated by using a published example.
Crowd-powered experts: helping surgeons interpret breast cancer images

Crowdsourcing is often applied for the task of replacing the scarce or expensive labour of experts with that of untrained workers. In this paper, we argue, that this objective might not always be desirable, but that we should instead aim at leveraging the considerable work force of the crowd in order to support the highly trained expert. In this paper, we demonstrate this different paradigm on the example of detecting malignant breast cancer in medical images. We compare the effectiveness and efficiency of experts to that of crowd workers, finding significantly better performance at greater cost. In a second series of experiments, we show how the comparably cheap results produced by crowdsourcing workers can serve to make experts more efficient AND more effective at the same time.
Biomedical Semantic Indexing using Dense Word Vectors in BioASQ

Background: Biomedical curators are often required to semantically index large numbers of biomedical articles, using hierarchically related labels (e.g., MeSH headings). Large scale hierarchical classification, a branch of machine learning, can facilitate this procedure, but the resulting automatic classifiers are often inefficient because of the very large dimensionality of the dominant bag-of-words representation of texts. Feature selection quickly harms the accuracy of the classifiers in this particular task, and dimensionality reduction transformations (e.g., PCA-based) usually cannot be efficiently applied to very large corpora.
The Influences of Negativity and Review Quality on the Helpfulness of Online Reviews

Building on the interpersonal evaluation theory in social psychology, this study explores the existence of a negativity bias in evaluating the helpfulness of online reviews, i.e., whether users perceive a negative review to be more helpful than a positive review. An analysis of 7659 book reviews from Amazon.co.uk shows that a negativity bias disappears after controlling for moderating factors related to evaluation quality such as readability and length. The finding demonstrates that the negativity bias suggested by the social psychology literature is not readily applicable to consumer-generated online reviews. The study contributes to the theorization of word-of-mouth by exploring the qualitative characteristics of consumer-generated reviews in addition to their valence. The study also makes a theoretical contribution to information systems research by introducing and extending the interpersonal evaluation theory to online review research.
Non-invasive 3D Visualization and Thickness Analysis of the Human Insula

Anatomical variability of the human insula has not been well studied because the structure of the insula is difficult to image. Thus, the aim of this study was to apply a novel method to reconstruct insular topology in order to assess the anatomic variation within a population. An analysis of 60 healthy male and female subjects revealed a significant amount of anatomic variation. Some structures, such as the central sulcus were extremely stable and showed little inter-individual variability, while other structures such as the middle short gyrus were highly variable, being more conspicuous in the left hemisphere and in males. Grey matter in the cortex was found to be thinner in the left posterior and dorsal insular subregions in older female subjects but not males. This work shows that the insula is an anatomically complex and variable structure and that some of the variability is related to sex and laterality.
Influence of dietary protein supplements on the formation of bacterial metabolites in the colon.

BACKGROUND: To evaluate the influence of increased dietary protein intake on bacterial colonic metabolism in healthy volunteers. METHODS: Short chain fatty acids, ammonia, and volatile organic compounds in faecal samples, and phenols in the urine of five volunteers were measured after one week of basal nutrient intake and and after one week of a diet supplemented with a protein rich food (Fortimel; Nutricia, Zoetermeer, The Netherlands). Paired t tests and factor analysis were used for statistical analysis. RESULTS: Total energy and resistant carbohydrate intake remained unchanged in each study period. The percentage energy intake delivered as dietary protein, increased significantly (from 15.4% to 23.8%; p = 0.007) during supplement intake. A significant increase in faecal ammonia (p = 0.002), faecal valeric acid (p = 0.02), and urinary p-cresol (p = 0.04) was noted during supplementary protein intake. A total of 120 different volatile compounds were isolated from the faecal samples of which 10 increased significantly during dietary protein supplementation. The change in volatile pattern, especially for S containing metabolites, was clearly shown by a factor analysis model which made a distinction between the two dietary regimens for all volunteers. CONCLUSION: An increase in dietary protein leads to altered products formation by colonic metabolism, mainly reflected by an increase in faecal ammonia, faecal volatile S substances, and urinary p-cresol.
NEWLY QUENCHED GALAXIES AS THE CAUSE FOR THE APPARENT EVOLUTION IN AVERAGE SIZE OF THE POPULATION

We use the large COSMOS sample of galaxies to study in an internally self-consistent way the change in the number densities of quenched early-type galaxies (Q-ETGs) of a given size over the redshift interval 0.2 < z < 1 in order to study the claimed size evolution of these galaxies. In a stellar mass bin at 1010.5 < Mgalaxy < 1011 M☉, we see no change in the number density of compact Q-ETGs over this redshift range, while in a higher mass bin at >1011 M☉, where we would expect merging to be more significant, we find a small decrease, by ∼30%. In both mass bins, the increase of the median sizes of Q-ETGs with time is primarily caused by the addition to the size function of larger and more diffuse Q-ETGs. At all masses, compact Q-ETGs become systematically redder toward later epochs, with a (U − V) color difference which is consistent with a passive evolution of their stellar populations, indicating that they are a stable population that does not appreciably evolve in size. We find furthermore, at all epochs, that the larger Q-ETGs (at least in the lower mass bin) have average rest-frame colors that are systematically bluer than those of the more compact Q-ETGs, suggesting that the former are indeed younger than the latter. The idea that new, large, Q-ETGs are responsible for the observed growth in the median size of the population at a given mass is also supported by analysis of the sizes and number of the star-forming galaxies that are expected to be the progenitors of the new Q-ETGs over the same period. In the low mass bin, the new Q-ETGs appear to have ∼30% smaller half-light radii than their star-forming progenitors. This is likely due to the fading of their disks after they cease star formation. Comparison with higher redshifts shows that the median size of newly quenched galaxies roughly scales, at constant mass, as (1 + z)−1. We conclude that the dominant cause of the size evolution seen in the Q-ETG population is that the average sizes and thus stellar densities of individual Q-ETGs roughly scale with the average density of the universe at the time when they were quenched, and that subsequent size changes in individual objects, through merging or other processes, are of secondary importance, especially at masses below 1011 M☉.
Effect of Low-Compression Balls on Wheelchair Tennis Match-Play

Abstract The purpose of this study was to compare court-movement variables and physiological responses to wheelchair tennis match-play when using low vs. standard compression tennis balls. Eleven wheelchair basketball players were monitored during repeated bouts of tennis (20 min) using both ball types. Graded and peak exercise tests were completed. For match-play, a data logger was used to record distance and speed. Individual linear heart rate oxygen consumption relationships were used to estimate match-play oxygen uptake. Significant main effects for ball type revealed that total distance (P<0.05), forward distance (P<0.05), and average speed (P<0.05) were higher for play using a low-compression ball. A lower percentage of total time was spent stationary (P<0.001), with significantly more time spent at speeds of 1–1.49 (P<0.05), 1.5–1.99 (P<0.05) and 2.0–2.49 (P<0.05) m ∙ sec−1 when using the low-compression ball. Main effects for physiological variables were not significant. Greater total and forward distance, and higher average speeds are achieved using a low-compression ball. The absence of any difference in measured HR and estimated physiological responses would indicate that players move further and faster at no additional mean physiological cost. This type of ball will be useful for novice players in the early phases of skill development.
A Screen for Genetic Suppressor Elements of Hepatitis C Virus Identifies a Supercharged Protein Inhibitor of Viral Replication

Genetic suppressor elements (GSEs) are biomolecules derived from a gene or genome of interest that act as transdominant inhibitors of biological functions presumably by disruption of critical biological interfaces. We exploited a cell death reporter cell line for hepatitis C virus (HCV) infection, n4mBid, to develop an iterative selection/enrichment strategy for the identification of anti-HCV GSEs. Using this approach, a library of fragments of an HCV genome was screened for sequences that suppress HCV infection. A 244 amino acid gene fragment, B1, was strongly enriched after 5 rounds of selection. B1 derives from a single-base frameshift of the enhanced green fluorescent protein (eGFP) which was used as a filler during fragment cloning. B1 has a very high net positive charge of 43 at neutral pH and a high charge-to-mass (kDa) ratio of 1.5. We show that B1 expression specifically inhibits HCV replication. In addition, five highly positively charged B1 fragments produced from progressive truncation at the C-terminus all retain the ability to inhibit HCV, suggesting that a high positive charge, rather than a particular motif in B1, likely accounts for B1’s anti-HCV activity. Another supercharged protein, +36GFP, was also found to strongly inhibit HCV replication when added to cells at the time of infection. This study reports a new methodology for HCV inhibitor screening and points to the anti-HCV potential of positively charged proteins/peptides.
HILT: a heavy ion large area proportional counter telescope for solar and anomalous cosmic rays

The HILT sensor has been designed to measure heavy ion elemental abundances, energy spectra, and direction of incidence in the mass range from helium to iron and in the energy range 4-250 MeV/nucleon. With its large geometric factor of 60 cm/sup 2/ sr the sensor is optimized to provide compositional and spectral measurements for low-intensity cosmic rays, i.e., for small solar energetic particle events and for the anomalous component of cosmic rays. The instrument combines a large-area ion-drift-chamber-proportional-counter system with two arrays of 16 Li-drifted solid state detectors and 16 CsI crystals. The multi-dE/dx-E technique provides a low-background mass and energy determination. The sensor also measures particle direction. By combining these measurements with the information on the spacecraft position and attitude in the low-altitude polar orbit, it will be possible to infer the ionic charge of the ions from the local cutoff of the Earth's magnetic field. The ionic charge in this energy range is of particular interest because it provides unique clues to the origin of these particles and has not been investigated systematically so far. >
Chlorophyll Degradation: The Tocopherol Biosynthesis-Related Phytol Hydrolase in Arabidopsis Seeds Is Still Missing1[C][W][OPEN]

Two known chlorophyll-related types of phytol hydrolases may only play limited roles in tocopherol biosynthesis in Arabidopsis seeds, implicating another unknown dephytylase that may exist. Phytyl diphosphate (PDP) is the prenyl precursor for tocopherol biosynthesis. Based on recent genetic evidence, PDP is supplied to the tocopherol biosynthetic pathway primarily by chlorophyll degradation and sequential phytol phosphorylation. Three enzymes of Arabidopsis (Arabidopsis thaliana) are known to be capable of removing the phytol chain from chlorophyll in vitro: chlorophyllase1 (CLH1), CLH2, and pheophytin pheophorbide hydrolase (PPH), which specifically hydrolyzes pheophytin. While PPH, but not chlorophyllases, is required for in vivo chlorophyll breakdown during Arabidopsis leaf senescence, little is known about the involvement of these phytol-releasing enzymes in tocopherol biosynthesis. To explore the origin of PDP for tocopherol synthesis, seed tocopherol concentrations were determined in Arabidopsis lines engineered for seed-specific overexpression of PPH and in single and multiple mutants in the three genes encoding known dephytylating enzymes. Except for modestly increasing tocopherol content observed in the PPH overexpressor, none of the remaining lines exhibited significantly reduced tocopherol concentrations, suggesting that the known chlorophyll-derived phytol-releasing enzymes do not play major roles in tocopherol biosynthesis. Tocopherol content of seeds from double mutants in NONYELLOWING1 (NYE1) and NYE2, regulators of chlorophyll degradation, had modest reduction compared with wild-type seeds, although mature seeds of the double mutant retained significantly higher chlorophyll levels. These findings suggest that NYEs may play limited roles in regulating an unknown tocopherol biosynthesis-related phytol hydrolase. Meanwhile, seeds of wild-type over-expressing NYE1 had lower tocopherol levels, suggesting that phytol derived from NYE1-dependent chlorophyll degradation probably doesn’t enter tocopherol biosynthesis. Potential routes of chlorophyll degradation are discussed in relation to tocopherol biosynthesis.