Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Quality of Life among Middle Aged and Elderly Women Participating in Health Dance Exercise

The purpose of this study was to analyze QOL among middle aged and elderly women participating in health dance exercise. This study used a cross-sectional survey design. The data collected from 192 women during August to September in 2013 using a questionnaire. Collected data were analyzed using frequency, independent t-test, one-way ANOVA, Correlation and multiple regression with the SPSS 21.0. Mean scores for BMI, body image, self-esteem, psychological happiness, leisure satisfaction and QOL were 22.1, 3.02 (5-point scale), 2.80 (4-point scale), 3.39 (5-point scale), 3.75 (5-point scale), and 3.47 (5-point scale) respectively. Self-esteem, health status, marital status and psychological happiness accounted for 53.4% of the variance in quality of life among those participating in health dance exercise. To promote the QOL of women participating in health dance exercise, self-esteem, health status, marital status and psychological happiness should be considered as important factors.
BRIEF REPORTS Action Type and Goal Type Modulate Goal-Directed Gaze Shifts in 14-Month-Old Infants

Ten- and 14-month-old infants gaze was recorded as the infants observed videos of different handactions directed toward multiple goals. Infants observed an actor who (a) reached for objects anddisplaced them, (b) reached for objects and placed them inside containers, or (c) moved his fisted hand.Fourteen-month-olds, but not 10-month-olds, anticipated the goal of reaching actions but tracked all theother actions reactively. Fourteen-month-olds also produced more anticipatory gaze shifts during con-tainment compared with displacement and differentiated between reaching actions dependent on whetherthe overall goal was to displace objects or place objects inside containers. These results demonstrate thataction type and goal type modulate the latency of goal-directed gaze shifts in infants.
Papillary fibroblasts differentiate into reticular fibroblasts after prolonged in vitro culture

The dermis can be divided into two morphologically different layers: the papillary and reticular dermis. Fibroblasts isolated from these layers behave differently when cultured in vitro. During skin ageing, the papillary dermis decreases in volume. Based on the functional differences in vitro, it is hypothesized that the loss of papillary fibroblasts contributes to skin ageing. In this study, we aimed to mimic certain aspects of skin ageing by using high‐passage cultures of reticular and papillary fibroblasts and investigated the effect of these cells on skin morphogenesis in reconstructed human skin equivalents. Skin equivalents generated with reticular fibroblasts showed a reduced terminal differentiation and fewer proliferating basal keratinocytes. Aged in vitro papillary fibroblasts had increased expression of biomarkers specific to reticular fibroblasts. The phenotype and morphology of skin equivalents generated with high‐passage papillary fibroblasts resembled that of reticular fibroblasts. This demonstrates that papillary fibroblasts can differentiate into reticular fibroblasts in vitro. Therefore, we hypothesize that papillary fibroblasts represent an undifferentiated phenotype, while reticular fibroblasts represent a more differentiated population. The differentiation process could be a new target for anti‐skin‐ageing strategies.
An Electronic Publication Dedicated to Early Stellar Evolution and Molecular Clouds Circumstellar Material in the Vega Inner System Revealed by Chara/fluor the H Ii Region of the First Star

Context. Only a handful of debris disks have been imaged up to now. Due to the need for high dynamic range and high angular resolution, very little is known about the inner planetary region, where small amounts of warm dust are expected to be found. Aims. We investigate the close neighbourhood of Vega with the help of infrared stellar interferometry and estimate the integrated K-band flux originating from the central 8 AU of the debris disk. Methods. We performed precise visibility measurements at both short (∼30 m) and long (∼150 m) baselines with the FLUOR beam-combiner installed at the CHARA Array (Mt Wilson, California) in order to separately resolve the emissions from the extended debris disk (short baselines) and from the stellar photosphere (long baselines). Results. After revising Vega's K-band angular diameter (θ UD = 3.202 ± 0.005 mas), we show that a significant deficit in squared visibility (∆V 2 = 1.88 ± 0.34%) is detected at short baselines with respect to the best-fit uniform disk stellar model. This deficit can be either attributed to the presence of a low-mass stellar companion around Vega, or as the signature of the thermal and scattered emissions from the debris disk. We show that the presence of a close companion is highly unlikely, as well as other possible perturbations (stellar morphology, calibration), and deduce that we have most probably detected the presence of dust in the close neighbourhood of Vega. The resulting flux ratio between the stellar photosphere and the debris disk amounts to 1.29 ± 0.19% within the FLUOR field-of-view (∼7.8 AU). Finally, we complement our K-band study with archival photometric and interferometric data in order to evaluate the main physical properties of the inner dust disk. The inferred properties suggest that the Vega system could be currently undergoing major dynamical perturbations.
Polynomial-time solution of prime factorization and NP-hard problems with digital memcomputing machines

We introduce a class of digital machines, we name Digital Memcomputing Machines, (DMMs) able to solve a wide range of problems including Non-deterministic Polynomial (NP) ones with polynomial resources (in time, space, and energy). An abstract DMM with this power must satisfy a set of compatible mathematical constraints underlying its practical realization. We prove this by making a connection with the dynamical systems theory. This leads us to a set of physical constraints for poly-resource resolvability. Once the mathematical requirements have been assessed, we propose a practical scheme to solve the above class of problems based on the novel concept of self-organizing logic gates and circuits (SOLCs). These are logic gates and circuits able to accept input signals from any terminal, without distinction between conventional input and output terminals. They can solve boolean problems by self-organizing into their solution. They can be fabricated either with circuit elements with memory (such as memristors) and/or standard MOS technology. Using tools of functional analysis, we prove mathematically the following constraints for the poly-resource resolvability: (i) SOLCs possess a global attractor; (ii) their only equilibrium points are the solutions of the problems to solve; (iii) the system converges exponentially fast to the solutions; (iv) the equilibrium convergence rate scales at most polynomially with input size. We finally provide arguments that periodic orbits and strange attractors cannot coexist with equilibria. As examples, we show how to solve the prime factorization and the search version of the NP-complete subset-sum problem. Since DMMs map integers into integers, they are robust against noise and hence scalable. We finally discuss the implications of the DMM realization through SOLCs to the NP = P question related to constraints of poly-resources resolvability.
Preconception care in diabetic women

Introduction: Diabetes is increasingly becoming prevalent worldwide. Pregnancy with diabetes is prone to maternal and fetal complications. Preconception care (PCC) is an important factor in alleviating gestational complications in those women who suffer from diabetes. This study seeks to gain insight into experiences of diabetic women and providers about PCC. Subjects and Methods: The present research was a qualitative research conducted on eight women with diabetes during the reproductive age and 15 health care providers of the public and private medical centers, which provide health care for women with diabetes in Isfahan (Iran), with a qualitative approach. Based on the aims of research, purposive sampling was done through semi-structuralized individual interview. Data were analyzed using conventional qualitative content analysis method. Results: Data analysis revealed three major categories: (1) Health centers weakness in providing PCC for diabetic women, (2) lack of a comprehensive PCC plan for diabetic women and (3) diabetic women's negligence about having planned pregnancy. Conclusion: In order to improve diabetic women's health, precise training of students, health care providers and patients themselves with respect to PCCs should be taken into account. Designing diabetic PCC system is an essential factor to succeed in this trend.
Transient receptor potential (TRP) channels: a clinical perspective

Transient receptor potential (TRP) channels are important mediators of sensory signals with marked effects on cellular functions and signalling pathways. Indeed, mutations in genes encoding TRP channels are the cause of several inherited diseases in humans (the so‐called ‘TRP channelopathies’) that affect the cardiovascular, renal, skeletal and nervous systems. TRP channels are also promising targets for drug discovery. The initial focus of research was on TRP channels that are expressed on nociceptive neurons. Indeed, a number of potent, small‐molecule TRPV1, TRPV3 and TRPA1 antagonists have already entered clinical trials as novel analgesic agents. There has been a recent upsurge in the amount of work that expands TRP channel drug discovery efforts into new disease areas such as asthma, cancer, anxiety, cardiac hypertrophy, as well as obesity and metabolic disorders. A better understanding of TRP channel functions in health and disease should lead to the discovery of first‐in‐class drugs for these intractable diseases. With this review, we hope to capture the current state of this rapidly expanding and changing field.
Differentially private data analysis of social networks via restricted sensitivity

We introduce the notion of restricted sensitivity as an alternative to global and smooth sensitivity to improve accuracy in differentially private data analysis. The definition of restricted sensitivity is similar to that of global sensitivity except that instead of quantifying over all possible datasets, we take advantage of any beliefs about the dataset that a querier may have, to quantify over a restricted class of datasets. Specifically, given a query f and a hypothesis HH about the structure of a dataset D, we show generically how to transform f into a new query fHH whose global sensitivity (over all datasets including those that do not satisfy HH) matches the restricted sensitivity of the query f. Moreover, if the belief of the querier is correct (i.e., D ∈ HH) then fHH(D) = f(D). If the belief is incorrect, then fHH(D) may be inaccurate. We demonstrate the usefulness of this notion by considering the task of answering queries regarding social-networks, which we model as a combination of a graph and a labeling of its vertices. In particular, while our generic procedure is computationally inefficient, for the specific definition of H as graphs of bounded degree, we exhibit efficient ways of constructing fH using different projection-based techniques. We then analyze two important query classes: subgraph counting queries (e.g., number of triangles) and local profile queries (e.g., number of people who know a spy and a computer-scientist who know each other). We demonstrate that the restricted sensitivity of such queries can be significantly lower than their smooth sensitivity. Thus, using restricted sensitivity we can maintain privacy whether or not D ∈ HH, while providing more accurate results in the event that HH holds true.
Information technologies and the development of professional knowledge and identity in teacher education

This paper addresses the preparation in ICT of preservice mathematics teachers. We describe the aims, assumptions, and work carried out in a course offered at the University of Lisbon and briefly discuss the processes involved in the development of professional knowledge and the formation of professional identities. Using a qualitative methodology, based on the administration of free-response questionnaires to the student teachers enrolled in the course in 1999-2000, we analyze their general perspectives about ICT, the implications of the use of ICT in their view of teaching methodologies, and their development of a professional identity. This work provides suggestions for teacher education practice and for further research.
Longitudinal change in reproductive hormones and depressive symptoms across the menopausal transition: results from the Study of Women's Health Across the Nation (SWAN).

CONTEXT The contribution of reproductive hormones to mood has been the focus of considerable research. Results from clinical and epidemiological studies have been inconsistent. It remains unclear whether alterations in serum hormone levels across the menopausal transition are linked to depressive symptoms. OBJECTIVES To evaluate the relationship between serum hormone levels and high depressive symptoms and whether hormone levels or their change might explain the association of menopausal status with depressive symptoms previously reported in a national sample of midlife women. DESIGN A longitudinal, community-based, multisite study of menopause. Data were collected at baseline and annually from December 1995 to January 2008 on a range of factors. Early follicular phase serum samples were assayed for levels of estradiol, follicle-stimulating hormone, testosterone, and dehydroepiandrosterone sulfate. SETTING Seven communities nationwide. PARTICIPANTS A community-based sample of 3302 multiethnic women, aged 42 to 52 years, still menstruating and not using exogenous reproductive hormones. Main Outcome Measure Depressive symptoms assessed with the Center for Epidemiological Studies Depression Scale (CES-D). The primary outcome was a CES-D score of 16 or higher. RESULTS In multivariable random-effects logistic regression models, log-transformed testosterone level was significantly positively associated with higher odds of a CES-D score of 16 or higher (odds ratio = 1.15; 95% confidence interval, 1.01-1.31) across 8 years, and a larger increase in log-transformed testosterone from baseline to each annual visit was significantly associated with increased odds of a CES-D score of 16 or higher (odds ratio = 1.23; 95% confidence interval, 1.04-1.45). Less education, being Hispanic, and vasomotor symptoms, stressful life events, and low social support at each visit were each independently associated with a CES-D score of 16 or higher. No other hormones were associated with a CES-D score of 16 or higher. Being perimenopausal or postmenopausal compared with being premenopausal remained significantly associated with a CES-D score of 16 or higher in all analyses. CONCLUSIONS Higher testosterone levels may contribute to higher depressive symptoms during the menopausal transition. This association is independent of menopausal status, which remains an independent predictor of higher depressive symptoms.
Comparative in vitro activities of cefpiramide and apalcillin individually and in combination

The in vitro activities of cefpiramide and apalcillin were compared with those of other third-generation cephalosporins and extended-spectrum penicillins against over 1,000 clinical bacterial isolates. The activity of cefpiramide against Pseudomonas aeruginosa was comparable to those of piperacillin and cefoperazone, inhibiting 90% of strains at concentrations less than or equal to 16.0 micrograms/ml. This drug was also active against a broad range of gram-negative organisms but was generally less active than many of the other cephalosporins tested against members of the family Enterobacteriaceae. The activity of cefpiramide against gram-positive organisms was comparable to that of cefoperazone. Apalcillin, along with ceftazidime, was the most active agent tested against P. aeruginosa and Acinetobacter calcoaceticus subsp. anitratus, inhibiting 90% of these strains at concentrations less than or equal to 8 micrograms/ml. Against other gram-negative and gram-positive organisms, its activity was similar to that of piperacillin. The activities of both cefpiramide and apalcillin were significantly reduced by the presence of several plasmid-mediated beta-lactamases in a series of otherwise isogenic strains of P. aeruginosa in comparison with their activities against a parent strain which lacks these enzymes. Many strains of Enterobacter cloacae were synergistically inhibited by the combination of gentamicin with either cefpiramide (5 of 10 strains) or apalcillin (6 of 10 strains). Most strains of P. aeruginosa were synergistically inhibited by the combination of gentamicin with either cefpiramide (8 of 10 strains) or apalcillin (10 of 10 strains). However, cefoxitin antagonized the activity of both cefpiramide and apalcillin against most of these same strains.
A Tailored Web-Based Intervention to Promote Women's Perceptions of and Intentions for Mammography

Background: The Internet is rapidly becoming an accepted standard for disseminating and obtaining health information. However, health information presented on the Web frequently is neither tailored to patients' characteristics nor theoretically driven. This study used Prochaska's transtheoretical model to guide the design and evaluation of a tailored Web-based mammography educational program. Purpose: This study used a pretest-posttest design to examine the impact of a tailored Web-based educational intervention on women's perceptions of and intentions to obtain a mammography. We hypothesized that a complete tailored intervention (CTI) would result in a significantly higher score than that of tailored message intervention (TMI) in terms of women's perceptions of mammography and intentions to receive a mammography. Both TMI and CTI have been found to have significantly higher scores in terms of women's perceptions of mammography and intentions to receive a mammography than those of the standard intervention (SI). Methods: One hundred eighty-five women were assigned randomly to one of three groups: CTI (n = 61), TMI (n = 63), or SI (n = 61). Online questionnaires were completed by participants at baseline and after completion of intervention. Results: Study results supported the hypothesis of perceptions of mammography. The CTI group had significantly higher scores on intention to obtain a mammogram than those of the SI group. However, the differences between CTI and TMI groups and between TMI and SI groups were not significant. Conclusions and Implications for Practice: Results of the study validated the importance of utilizing theory for tailored intervention design to enhance individuals' positive perceptions of health behaviors. Additional studies should consider the effect of various processes and activities on women at different stages of acceptance of the need to obtain a mammogram to further determine outcomes and apply such to mammography screening behavior.
On middle cube graphs

We study a family of graphs related to the $n$-cube. The middle cube graph of parameter k is the subgraph of $Q_{2k-1}$ induced by the set of vertices whose binary representation has either $k-1$ or $k$ number of ones. The middle cube graphs can be obtained from the well-known odd graphs by doubling their vertex set. Here we study some of the properties of the middle cube graphs in the light of the theory of distance-regular graphs. In particular, we completely determine their spectra (eigenvalues and their multiplicities, and associated eigenvectors).
Query classification using Wikipedia

Identifying the intended topic that underlies a user's query can benefit a large range of applications, from search engines to question-answering systems. However, query classification remains a difficult challenge due to the variety of queries a user can ask, the wide range of topics users can ask about, and the limited amount of information that can be mined from the query. In this paper, we develop a new query classification system that accounts for these three challenges. Our system relies on the freely-available online encyclopedia Wikipedia as a natural-language knowledge-based, and exploits Wikipedia's structure to infer the correct classification of any given query. We will present two variants of this query classification system in this paper, and demonstrate their reliability compared to each other and to the literature benchmarks using the query sets from the KDD CUP 2005 and TREC 2007 competitions.
Parenteral nutritional support in children with cancer

Acute and chronic starvation is often associated with childhood cancer. Total parenteral nutrition (TPN) with 20% glucose and 3.0% amino acids, and minerals and vitamins was instituted to treat or prevent malnutrition in 41 children with cancer, ages three months to 18 years. TPN was required for anorexia, vomiting and diarrhea associated with anti‐cancer therapy in 33 patients for intestinal complications or surgery in nine, and for preoperative correction of malnutrition in two. During TPN, general nutrition and appearance improved in all patients. Weight gain was noted in most. Despite gastrointestinal complications which usually require the interruption of chemotherapy and irradiation, in 21 children treatment could be continued at full dose with nutritional support by TPN. TPN was discontinued in six patients when blood cultures became positive. Sepsis was treated successfully by removal of the central venous catheter in all six and administration of antibiotics in three. No metabolic complications were noted. TPN appears to be a safe and effective means of combating the malnutrition which may occur with cancer and its therapy.
Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects

Background Adult weight gain and obesity have become worldwide problems. Issues of cost and potential side effects of prescription weight loss drugs have led overweight and obese adults to try nutraceuticals that may aid weight loss. One promising nutraceutical is green coffee extract, which contains high concentrations of chlorogenic acids that are known to have health benefits and to influence glucose and fat metabolism. A 22-week crossover study was conducted to examine the efficacy and safety of a commercial green coffee extract product GCA™ at reducing weight and body mass in 16 overweight adults. Methods Subjects received high-dose GCA (1050 mg), low-dose GCA (700 mg), or placebo in separate six-week treatment periods followed by two-week washout periods to reduce any influence of preceding treatment. Treatments were counterbalanced between subjects. Primary measurements were body weight, body mass index, and percent body fat. Heart rate and blood pressure were also measured. Results Significant reductions were observed in body weight (−8.04 ± 2.31 kg), body mass index (−2.92 ± 0.85 kg/m2), and percent body fat (−4.44% ± 2.00%), as well as a small decrease in heart rate (−2.56 ± 2.85 beats per minute), but with no significant changes to diet over the course of the study. Importantly, the decreases occurred when subjects were taking GCA. Body mass index for six subjects shifted from preobesity to the normal weight range (<25.00 kg/m2). Conclusion The results are consistent with human and animal studies and a meta-analysis of the efficacy of green coffee extract in weight loss. The results suggest that GCA may be an effective nutraceutical in reducing weight in preobese adults, and may be an inexpensive means of preventing obesity in overweight adults.