Miracle-dz/UniFAR-FTUs huggingface dataset:
Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women

Research Question Preterm birth (PTB) is the leading cause of perinatal mortality worldwide, with the greatest burden occurring in resource-constrained settings. Based on the hypothesis that altered placental angiogenesis and inflammation early in pregnancy lead to PTB, we examined whether levels of inflammatory and angiogenic mediators, measured early in pregnancy, were predictive of spontaneous PTB (sPTB). Study Design Plasma samples were collected from a prospective cohort of primigravid Tanzanian women between 12–27 weeks gestation. A panel of 18 markers was screened on a training cohort of 426 women. Markers associated with sPTB in the training cohort were repeated in a test cohort of 628 women. All markers were measured by ELISA. Findings In both the training and test cohorts plasma levels of IL-18BP, sICAM-1, sEndoglin and CHI3L1 were elevated and Leptin was lower at enrollment in women who subsequently experienced sPTB. In multivariate analysis women with plasma levels of CHI3L1, C5a, sICAM-1, AngptL3, sEndgolin, sFlt-1 and IL-18BP in the highest quartile had an increased risk of sPTB compared with those in the lowest quartile. Women with Leptin and Ang2 in the highest quartile had a reduced risk of sPTB compared with women in the lowest quartile. Implications Levels of angiogenic and inflammatory mediators measured at mid-pregnancy were associated with subsequent sPTB. These findings provide insight into mechanisms underlying sPTB and suggest biomarkers that may have clinical utility in risk-stratifying pregnancies.
The Influence of Social Desirability on Learning Process Questionnaires: A Neglected Possibility?

The Biggs' Learning Process Questionnaire and a short version of the Marlowe-Crowne Social Desirability Scale were administered to 83 male and 79 female Hong Kong 12- to 13-year-old secondary school students. Moderate, statistically significant correlations were found between a tendency to respond in a socially desirable way and surface and achieving strategy scales. These correlations differed for males and females. The results suggest that the validity of the learning process questionnaire may be threatened by the social desirability response set. In particular, research focusing on cross-cultural comparisons and gender differences in approaches to learning may need to consider the implications of this possible source of invalidity.
Increased intestinal macromolecular permeability and urine nitrite excretion associated with liver cirrhosis with ascites.

AIM To determine intestinal permeability, the serum tumor necrosis factor (TNF)-alpha level and urine nitric oxide (NO) metabolites are altered in liver cirrhosis (LC) with or without ascites. METHODS Fifty-three patients with LC and 26 healthy control subjects were enrolled in the study. The intestinal permeability value is expressed as the percentage of polyethylene glycol (PEG) 400 and 3350 retrieval in 8-h urine samples as determined by high performance liquid chromatography. Serum TNF-alpha concentrations and urine NO metabolites were determined using an enzyme-linked immunosorbent assay (ELISA) and Greiss reaction method, respectively. RESULTS The intestinal permeability index was significantly higher in patients with LC with ascites than in healthy control subjects or patients with LC without ascites (0.88 +/- 0.12 vs 0.52 +/- 0.05 or 0.53 +/- 0.03, P < 0.05) and correlated with urine nitrite excretion (r = 0.98). Interestingly, the serum TNF-alpha concentration was significantly higher in LC without ascites than in control subjects or in LC with ascites (198.9 +/- 55.8 pg/mL vs 40.9 +/- 12.3 pg/mL or 32.1 +/- 13.3 pg/mL, P < 0.05). Urine nitrite excretion was significantly higher in LC with ascites than in the control subjects or in LC without ascites (1170.9 +/- 28.7 micromol/L vs 903.1 +/- 55.1 micromol/L or 956.7 +/- 47.7 micromol/L, P < 0.05). CONCLUSION Increased intestinal macromolecular permeability and NO is probably of importance in the pathophysiology and progression of LC with ascites, but the serum TNF-alpha concentration was not related to LC with ascites.
Clothing functions and use of clothing to alter mood

The purpose of our study was to examine the antecedents to use of clothing to alter mood by identifying personality traits, social appearance anxiety, clothing in relation to self as structure (CSS), and clothing functions. Undergraduate women participated (n=310) in the study. Path analysis using structural equation modelling was used to test our hypothesised model. Perfectionism was related to social appearance anxiety and CSS. Neuroticism was related to social appearance anxiety. Individuals who experienced social appearance anxiety tended to select clothing for its ability to provide comfort, camouflage flaws in appearance, and provide assurance. Individuals who felt a close connection between clothing and the self (CSS) tended to select clothing for its ability to camouflage flaws in appearance and provide assurance, fashionability, and individuality. CSS in combination with the camouflage clothing function played the most important role in predicting the use of clothing to alter mood.
Strategies to Increase Reading Fluency

Problems in reading fluency have long been considered to be among the most common characteristics of students with mild disabilities and other special needs. In this article, we review research on reading fluency and provide recommendations for practice. Interventions that have received research attention include repeated reading, peer-mediated instruction, computer-guided practice, previewing, and combined approaches.
Changing Welfare States and the “Sandwich Generation” : Increasing Burden for the Next Generation?

The burden placed on individuals aged 40 to 59 – especially on women – by competing demands from work and both older and younger family members is often addressed using the metaphor of the “sandwich generation”. Based on a systematization of the definitions used in the literature, empirical evidence on the frequency of such generational constellations and on their impact on the well-being of sandwiched adults will be presented. Analysing the second wave of the German Aging Survey shows that being sandwiched – defined as a generational constellation – is very common, but simultaneous care activities for both older and younger family members are rare, especially in combination with labour force participation, and that life satisfaction is not systematically related to being sandwiched. Implications for further research and future developments will be discussed, especially with respect to changes in family structure (e.g. the beanpole family) and changes in the amount of welfare state spending for the aged.
Sexual and violent offenders’ victim role assignments: a general model of offending style

Although distinct offence action patterns have been identified for different forms of sexual and violent crime, a generic psychological framework for this differentiation has yet to be advanced. An innovative framework derived from the emerging criminal narrative approach provides a significant contribution to the differentiation of offending styles. Canter (1994) argues that offenders’ empathy deficit leads them to assign a Victim, Object or Person role to their victims within their personal narratives. The evidence for this model is examined across 33 offence actions in 66 stranger rapes, 24 offence actions in 50 stalking offences and 39 offence actions in 50 serial murder offences. Hypothesised offence actions reflecting the Roles are found in distinct regions of Smallest Space Analysis (SSA-I) configurations for all three offence types. This evidence across diverse offence forms leads to the suggestion that the Roles assigned to victims within offenders’ narratives provide a generic framework for differentiating offending styles in all interpersonal crimes. The different Victim Roles articulate qualitatively different variants of the established control and empathy deficit components in sexual and violent offending, contributing to the debate about the operation of these components and having significant treatment implications.
A Deep Study of a New Energy Efficient Routing Protocol for Mobile Ad-hoc Networks

Routing in MANETs ( Mobile Ad-hoc Networks) is a very hard task due to their dynamic topology and th eir decentralized nature. Moreover, limited-energy resources make bot h nodes and network lifetime among the main issues to be consid ere in MANETs’ routing protocols design. This paper discus ses many aspects related to routing in MANETs and presents M EA-DSR, a new energy-aware routing protocol. A deep simulatio n study is also presented showing the efficiency of our routing-pol icy proposal in many challenging scenarios. Key-words: Mobile Adhoc Networks, Routing Protocols, Energy efficiency.
Retrieval of action names in aphasia: Effects of two cueing treatments

Background: The treatment of word-retrieval deficits in aphasia has most frequently focused on the retrieval of object names. The retrieval of action names has received relatively little attention in terms of rehabilitation despite the important role played by verbs in communication. Treatments that have been successful in promoting improved object name retrieval cannot be assumed to also facilitate improved action name retrieval. Aims: The purpose of this investigation was to examine the effects of two cueing treatments on the retrieval of action names with speakers with chronic aphasia. Methods & Procedures: The effects of two cueing treatments, Phonological Cueing Treatment (PCT) and Semantic Cueing Treatment (SCT), were examined with five speakers with aphasia. Treatment effects on action naming were measured using single subject, multiple baseline, and alternating treatments designs. Outcomes & Results: Results varied across participants. For two speakers, both treatments produced strong positive increases in naming, with effects being similar across treatments. For two other speakers, modest increases in correct naming were observed and for the remaining speaker, no increases were found. Conclusions: These findings indicate that PCT and SCT may have utility in facilitating action naming for some speakers with aphasia, but that the effects may vary across speakers.
Cold drink ingestion improves exercise endurance capacity in the heat.

PURPOSE To investigate the effect of drink temperature on cycling capacity in the heat. METHODS On two separate trials, eight males cycled at 66 +/- 2% VO2peak (mean +/- SD) to exhaustion in hot (35.0 +/- 0.2 degrees C) and humid (60 +/- 1%) environments. Participants ingested three 300-mL aliquots of either a cold (4 degrees C) or a warm (37 degrees C) drink during 30 min of seated rest before exercise and 100 mL of the same drink every 10 min during exercise. Rectal and skin temperatures, heart rate, and sweat rate were recorded. Ratings of thermal sensation and perceived exertion were assessed. RESULTS Exercise time was longer (P < 0.001) with the cold drink (63.8 +/- 4.3 min) than with the warm drink (52.0 +/- 4.1 min). Rectal temperature fell by 0.5 +/- 0.1 degrees C (P < 0.001) at the end of the resting period after ingestion of the cold drinks. There was no effect of drink temperature on mean skin temperature at rest (P = 0.870), but mean skin temperature was lower from 20 min during exercise with ingestion of the cold drink than with the warm drink (P < 0.05). Heart rate was lower before exercise and for the first 35 min of exercise with ingestion of the cold drink than with the warm drink (P < 0.05). Drink temperature influenced sweat rate (1.22 +/- 0.34 and 1.40 +/- 0.41 L x h(-1) for the cold and the warm drink, respectively; P < 0.05). Ratings of thermal sensation and perceived exertion (P < 0.01) during exercise were lower when the cold drink was ingested. CONCLUSION Compared with a drink at 37 degrees C, the ingestion of a cold drink before and during exercise in the heat reduced physiological strain (reduced heat accumulation) during exercise, leading to an improved endurance capacity (23 +/- 6%).
Trends and determinants of antiresorptive drug use for osteoporosis among elderly women

It has been established that women who have had a first osteoporotic fracture are at a significantly greater risk of future fractures. Effective antiresorptive treatments (ART) are available to reduce this risk, yet little information is available on trends in ART drug use among the elderly. The objective is to estimate the rate ratio (RR) of having an ART prescription filled among elderly women and its relation to selected determinants from 1995 through 2001.
Equity in Marital Roles across the Family Life Cycle.

The objective of this study is to examine married couples' perceptions of equity/ inequity in the performance of selected marital roles at four stages of the family life cycle. A randomly selected sample of 336 couples was interviewed and asked their perception of thefairness of their own and of their spouses' efforts in the family roles of cooking, housekeeping, provider, companion, and parent. Perceived equity in family roles tended to increase over the life cycle for both husbands and wives while perceived inequity decreased. However, wives were more likely than husbands to perceive inequity that was unfavorable to them in three of the roles, whereas husbands were more likely than wives to perceive equity that was favorable to them in all the family roles.
Differences in Gender and Ethnicity as Measured by Ratings of Three Writing Tasks

The issue of racial/ethnic and gender differences in intelligence and academic abilities is fiercely and frequently debated, yet the examination of these differences in creativity is less studied. Our goal in this study was to use the Consensual Assessment Technique, in which experts judge a product's creativity, to examine differences in creativity among gender and ethnic groups. We conducted three separate analyses in which 13 experts rated 103 poems, 104 fictional stories, and 103 personal narratives written by Caucasian, African American, Latino/a, and Asian eighth-grade students. There were no significant African American-Caucasian differences on any of the writing tasks and there were no gender differences on all three tasks. The only significant differences in the creativity ratings on any of the tasks occurred in poetry, between the Latino/ a-Caucasian groups and Latino/a-Asian groups. Implications and future directions are discussed.
Cloning of a genetic determinant from Clostridium difficile involved in adherence to tissue culture cells and mucus

Our laboratory has previously shown that Clostridium difficile adherence to Caco-2 cells is greatly enhanced after heat shock at 60 degrees C and that it is mediated by a proteinaceous surface component. The experiments described here show that C. difficile could adhere to several types of tissue culture cells (Vero, HeLa, and KB) after heat shock. The type of culture medium (liquid or solid, with or without blood) had little effect on adhesion. To clone the adhesin gene, polyclonal antibodies against C. difficile heated at 60 degrees C were used to screen a genomic library of C. difficile constructed in lambda ZapII. Ten positive clones were identified in the library, one of which (pCL6) agglutinated several types of erythrocytes in the presence of mannose. In Western blots (immunoblots), this clone expressed in Escherichia coli a 40- and a 27-kDa protein; a 27-kDa protein has been previously identified in the surface extracts of heat-shocked C. difficile as a possible adhesin. The clone adhered to Vero, Caco-2, KB, and HeLa cells; the adherence was blocked by anti-C. difficile antibodies, by a surface extract of C. difficile, and by mucus isolated from axenic mice. Furthermore, the clone could attach ex vivo to intestinal mucus isolated from axenic mice. Preliminary studies on the receptor moieties implicated in C. difficile adhesion revealed that glucose and galactose could partially block adhesion to tissue culture cells, as did di- or trisaccharides containing these sugars, suggesting that the adhesin is a lectin. In addition, N-acetylgalactosamine, a component of mucus, and gelatin partially impeded cell attachment.
Time Course Changes in the Dopaminergic Nigrostriatal System Following Transection of the Medial Forebrain Bundle: Detection of Oxidatively Modified Proteins in Substantia Nigra

Abstract: We studied the time course of oxidatively modified proteins in the nigrostriatal dopaminergic system following transection of the medial forebrain bundle by quantifying the number of carbonyl groups coupled to striatal and nigral protein homogenates, an index of metal‐catalyzed oxidations. We found a striking effect of axotomy on the number of oxidatively modified proteins in the substantia nigra but not in the striatum within the first 5 days postlesion. This effect was correlated with the neurochemical activity of the dopaminergic and serotoninergic systems in the substantia nigra, which suggests a role of dopamine‐ and serotonin‐derived radical oxygen species in the oxidative stress detected in this brain area. We then searched for the type of cell death in the substantia nigra following axotomy. The fragmentation pattern obtained by agarose gel electrophoresis of DNA isolated from nigral tissue was indicative of cell death being entirely necrotic. In fact, no evidence of apoptosis was detected at any postlesion time as revealed by TdT‐mediated dUTP‐biotin nick end‐labeling (TUNEL) staining. The course of necrotic cell death in the substantia nigra coincided with the maximal levels of oxidatively modified proteins in the substantia nigra, suggesting a link between oxidative stress and nerve cell death and also coinciding with the neurochemical activity of both dopaminergic and serotoninergic systems.
MULTI-GROUP ANALYSIS OF ONLINE SHOPPING BY MO- BILITY IMPAIRED AND UNIMPAIRED USERS

Since van der Heijden (2004) it is widely accepted that hedonic and utilitarian information systems underlie different adoption mechanisms. Within this research, we compare two homogenous user groups and their adoption behaviors with respect to e-commerce websites. The groups thereby differ only in the fact that one of them consists of individuals suffering from mobility impairment. Consistent with theory in psychology and medical rehabilitation that suggests that disablement leads to an adapted evaluation of surroundings (including ICT) in terms of needs and purposes, we show by means of a multi-group structural equation analysis that concerning adoption determinants of a system, not only the mere system characteristics (utilitarian vs. hedonic) matter, but also the value that is attached to the system by the user in terms of his personal needs. The results indicate that although ecommerce websites are predominantly classified as hedonic system, the adoption of them by the mobility-impaired group is predominantly determined by perceived usefulness. This leads to the discussion if user characteristics in terms of physical capabilities and the needs they imply should be attached more importance to in IS adoption research.
Anteroposterior Spondyloschisis of Atlas With Incurving of the Posterior Arch Causing Compressive Myelopathy

Study Design. A case report of a patient with a combined anterior and posterior arch anomaly of atlas leading to compressive myelopathy. Objective. To describe a rare presentation of cervical stenosis at the atlas where congenital defects of the posterior arch with an incurving portion exists. This report includes a feasible hypothesis for the development of this anomaly on the basis of previous hypotheses and surgical findings. Summary of Background Data. Congenital defects of the posterior arch of atlas are uncommon and congenital symptomatic cervical stenosis is very rarely seen at this level. The congenital midline cleft of the posterior arch of an atlas has been described in patients with progressive motor symptoms and sensory deficit in extremities. Methods. An 11-year-old boy suffered from right side weakness for 1 year. His mother witnessed his awkward walking and clumsiness in using chopsticks and writing. His medical history was unremarkable, and there was no history of significant trauma. Right upper limb weakness of Grade IV/V and difficulty in hopping on right leg was checked on neurologic examination. The magnetic resonance image showed cervical canal stenosis at atlas level and high signal intensity change in the spinal cord. The computed tomography demonstrated partial defect at anterior and posterior arch of the atlas with incurving at defect site leading to cord compression. Suspecting one of craniovertebral junction anomalies, we performed a surgical resection of the posterior arch of the atlas (decompressive laminectomy). Results. The laminectomy was done. The defect site of the posterior arch was substituted with a cartilage and there was no dural adhesion. After surgery, right lower limb weakness was improved and no instability has been observed during 1-year follow-up. Conclusion. We describe the association between compressive myelopathy and combined anteroposterior spondyloschisis of an atlas with incurving of the arch at defect site. Both computed tomography and magnetic resonance image were required to demonstrate the bony configuration and cord compression. And decompressive laminectomy of atlas was effective as a treatment for this compressive myelopathy caused by midline defect in the posterior atlantal arch with bony incurving.
Cathodal Transcranial Direct Current Stimulation in Children With Dystonia

Studies suggest that dystonia is associated with increased motor cortex excitability. Cathodal transcranial direct current stimulation can temporarily reduce motor cortex excitability. To test whether stimulation of the motor cortex can reduce dystonic symptoms in children, we measured tracking performance and muscle overflow using an electromyogram tracking task before and after stimulation. Of 10 participants, 3 showed a significant reduction in overflow, and a fourth showed a significant reduction in tracking error. Overflow decreased more when the hand contralateral to the cathode performed the task than when the hand ipsilateral to the cathode performed the task. Averaged over all participants, the results did not reach statistical significance. These results suggest that cathodal stimulation may allow a subset of children to control muscles or reduce involuntary overflow activity. Further testing is needed to confirm these results in a blinded trial and identify the subset of children who are likely to respond.
An initial evaluation of the Convex SPP-1000 for earth and space science applications

The Convex SPP-1000, the most recent SPC, is distinguished by a true global shared memory capability based on the first commercial version of directory based cache coherence mechanisms and SCI protocol. The system was evaluated at NASA/GSFC in the Beta-test environment using three classes of operational experiments targeting earth and space science applications. A multiple program workload tested job-stream level parallelism. Synthetic programs measured overhead costs of barrier, fork-join, and message passing synchronization primitives. An efficient tree-code version of an N-body simulation revealed scaling properties and measured the overall efficiency. This paper presents the results of this study and provides the earliest published evaluation of this new scalable architecture. <<ETX>>
Low Power Wireless Smoke Alarm System in Home Fires

A novel sensing device for fire detection in domestic environments is presented. The fire detector uses a combination of several sensors that not only detect smoke, but discriminate between different types of smoke. This feature avoids false alarms and warns of different situations. Power consumption is optimized both in terms of hardware and software, providing a high degree of autonomy of almost five years. Data gathered from the device are transmitted through a wireless communication to a base station. The low cost and compact design provides wide application prospects.