Miracle-dz/UniFAR-FTUs huggingface dataset:
Sensitive Leisure: Writing the Lived Experience of Air Pollution

ABSTRACT We explore the sensory experiences of individuals who live, work, and play in an environment marred by air pollution. Sensory phenomenology provides a theoretical lens through which to analyze the experiences of residents living with and through air pollution events in the Salt Lake metropolitan area, Utah. Excerpts from ten essays are presented to support four researcher-developed themes and reflexive analyses. The role of the senses in negotiating air pollution during leisure experiences is discussed, as is the democratization of embodiment resulting from exposure to air pollution. We show how research that uses sensory descriptions as primary data can provide a radical closeness to the lived leisure experience as well as a replicable model for sensitive leisure scholarship.
The experiences of volunteers in a childhood cancer charity

Introduction: Serious childhood illness has a significant impact on the child and their family, but it is known that strong supportive relationships can act as a buffer. Due to limited NHS resources, volunteers are becoming integral to the support of such families. Despite this, little is known about the experiences of volunteers in such roles, and more specifically, those choosing to volunteer in emotionally challenging areas such as childhood cancer. Method: A sample of seven volunteers working for Candlelighters childhood cancer charity were interviewed using semi structured interviews; transcripts were analysed using interpretative phenomenological analysis. Results: Volunteer’s experiences of working in a childhood cancer charity were described in terms of five superordinate themes: ‘Motivation’, ‘Identity and Roles’, ‘Coping’, ‘Community’, and ‘Family’. Overall, the themes captured what motivates individuals to volunteer and in particular why they chose the area of childhood cancer. The themes also reflected the impact that the role has on their sense of identity and self, and how the participants seemed to cope with that role. It is speculated that this is in part due to the protective experience of belonging to a community as described by the participants, with frequent allusions to an even deeper link in terms of feeling part of a family. Discussion: The findings of this study are related to the wider literature with consideration of role identity theory and the significance of community and relationships. The strengths and limitations are discussed to assess the quality of the study. Implications for our current understanding of volunteers and suggestions for future research are proposed.
The impact of migration on intergenerational solidarity types

ABSTRACT This paper aims to expand knowledge on the effects of an international migration on parent–adult child relationships. We develop a typology, include non-migrants in the country of origin for comparison, and consider transnational families. Analyses are based on the Turkish 2000 Families Study, using information of adult non-co-resident children about their relationships with their parents. The research questions are: Do intergenerational solidarity types in migrant families reflect the patterns prevalent in the origin context or migration-specific adjustments? Do solidarity types of migrants differ, depending on whether they are transnational, of first- or second-generation children? Are differences due to composition effects? Latent class analysis shows four solidarity types. Their prevalence differs remarkably across the migrant groups. The proportion of the full-solidarity type is larger and that of the autonomous type is smaller in the relationships of first- and second-generation children with their migrant parents than among stayer dyads in Turkey. In transnational relationships, there is less full solidarity, and autonomous relationships are more likely. All migrant groups display less advice-oriented and more material-oriented support relationships. These results indicate stronger intergenerational cohesion in non-transnational migrant families and few changes across migrant generations. The observed differences are not due to composition effects.
Inexact semismooth Newton methods for large-scale complementarity problems

The semismooth Newton method is a nonsmooth Newton-type method applied to a suitable reformulation of the complementarity problem as a nonlinear and nonsmooth system of equations. It is one of the standard methods for solving these kind of problems, and it can be implemented in an inexact way so that all linear systems of equations have to be solved only inexactly. However, from a practical point of view, this inexact Newton method seems to have a significantly worse behavior than its exact counterpart. The aim of this paper is therefore to show that the inexact Newton method can also be used in a reliable and efficient way at least for some classes of problems. We illustrate this statement by some numerical examples with up to one million variables.
Breast Cancer “Tailored Follow-up” in Italian Oncology Units: A Web-Based Survey

Purpose Breast cancer follow-up procedures after primary treatment are still a controversial issue. Aim of this study was to investigate, through a web-based survey, surveillance methodologies selected by Italian oncologists in everyday clinical practice. Methods Referents of Italian medical oncology units were invited to participate to the study via e-mail through the SurveyMonkey website. Participants were asked how, in their institution, exams of disease staging and follow-up are planned in asymptomatic women and if surveillance continues beyond the 5th year. Results Between February and May 2013, 125 out of 233 (53.6%) invited referents of Italian medical oncology units agreed to participate in the survey. Ninety-seven (77.6%) referents state that modalities of breast cancer follow-up are planned according to the risk of disease progression at diagnosis and only 12 (9.6%) oncology units apply the minimal follow-up procedures according to international guidelines. Minimal follow-up is never applied in high risk asymptomatic women. Ninety-eight (78.4%) oncology units continue follow-up in all patients beyond 5 years. Conclusions Our survey shows that 90.4% of participating Italian oncology units declare they do not apply the minimal breast cancer follow-up procedures after primary treatment in asymptomatic women, as suggested by national and international guidelines. Interestingly, about 80.0% of interviewed referents performs the so called “tailored follow-up”, high intensity for high risk, low intensity for low risk patients. There is an urgent need of randomized clinical trials able to determine the effectiveness of risk-based follow-up modalities, their ideal frequency and persistence in time.
CALL FOR PAPERS Cardiovascular and Cerebrovascular Aging-New Mechanisms and Insights High-protein-low-carbohydrate diet: deleterious metabolic and cardiovascular effects depend on age

Tatiana Bedarida,* Stephanie Baron,* Emilie Vessieres, Francoise Vibert, Audrey Ayer, Carmen Marchiol-Fournigault, Daniel Henrion, Jean-Louis Paul, Florence Noble, Jean-Louis Golmard, Jean-Louis Beaudeux, Charles-Henry Cottart, and Valerie Nivet-Antoine Unite Mixte de Recherche-S 1140 Institut National de la Sante et de la Recherche Medicale, Faculty of Pharmacy, Paris Descartes University, Paris, France; Department of Physiology, Georges Pompidou European Hospital, Assistance PubliqueHopitaux de Paris, Paris, France; Unite Mixte de Recherche-S U970 Institut National de la Sante et de la Recherche Medicale, Faculty of Medicine, Paris Descartes University, Paris, France; Centre National de la Recherche Scientifique Unite Mixte de Recherche 6214, Institut National de la Sante et de la Recherche Medicale U1083, Angers University, Angers, France; Unite Mixte de Recherche-S 1139 Institut National de la Sante et de la Recherche Medicale, Faculty of Pharmacy, Paris Descartes University, Paris, France; Institut Cochin, Paris Descartes University, Paris, France; Department of Biochemistry, Georges Pompidou European Hospital, Assistance Publique-Hopitaux de Paris, Paris, France; EA 4529, Faculty of Pharmacy, Paris Sud University, Chatenay-Malabry, France; Institut National de la Sante et de la Recherche Medicale 705 Centre National de la Recherche Scientifique Unite Mixte de Recherche 8206, Faculty of Pharmacy, Paris Descartes University, Paris, France; ER4/EA 3974, Modeling in Clinical Research, Pierre and Marie Curie University, Paris, France; Clinical Biochemistry, Necker Hospital, Assistance Publique-Hopitaux de Paris, Paris, France; Unite Mixte de Recherche 1151 Institut National de la Sante et de la Recherche Medicale, Institut Necker-Enfants Malades, Paris Descartes University, Paris, France
Expression of the Na+-K+-2Cl--Cotransporter 2 in the Normal and Pressure-Induced Ischemic Rat Retina

Purpose To evaluate the expression of the Na+-K+-2Cl--cotransporter 2 (NKCC2) in the ischemic rat retina. Methods Retinal ischemia was induced by pressures 90 to 120 mmHg, above systemic systolic pressure. Immunohistochemistry and western blot analysis were performed. Results NKCC2 is expressed in the normal retina and its expression is increased by ischemia caused by intraocular pressure elevation. NKCC2 immunoreactivity was observed mainly in axon bundles of ganglion cells and horizontal cell processes in the retina. NKCC2 expression continuously increased with a peak value 3 days (to 415% of normal levels) after ischemic injury, and then gradually decreased to 314% of controls until 2 weeks post injury. The mean density of NKCC2-labeled ganglion cells per mm2 changed from 1,255 ± 109 in normal retinas to 391 ± 49 and 185 ± 37 at 3 days and 2 weeks after ischemia, respectively (p < 0.05), implying cell death of ganglion cells labeled with NKCC2. Conclusions Taken together, these results suggest that NKCC2, which is expressed in retinal ganglion and horizontal cells, may contribute to cell death by ischemic injury in the retina, although the molecular mechanisms involved remain to be clarified.
Practical Tools for Derivative Instruments based on Nonlinear Time Series Prediction

Derivative instruments are financial engineering tools. Th ey are linked to underlying financial instruments and are often better suited to manage exposure to risk. A number of tools exist for example for the management of interest rate risks. The optimal choice of a sp ecific instrument depends on a variety of factors. One crucial factor is the client’s estimate of inte rest rate developments in comparison to implied forward rates. The goal of the presented project is to develop practical com puter-based tools to assist market participants in assessing rate developments. In the area of int erest rate developments, we will analyze and predict rates using modern nonlinear models, such as multil ayer perceptrons. Unlike other approaches with nonlinear models, this consists of several steps: a mod el-selection step, based on an estimate of mean prediction error, including well known statistical me thods for time series prediction (ARMA); a step to estimate the predictive distribution, and a step to e valuate the predictive distribution in order to establish standard errors and confidence intervals. Predic tive distributions are estimated by less assumptive approaches, i. e. , bootstrap methods. Another important aspect is user interaction. We will integ rate assisting tools into existing software at the trade center of the Bankgesellschaft to facilitate it s use. Model selection and estimation is done automatically while parameters depending on the actual ris k management strategy, i. e. , the width of confidence intervals or the needed quantile, are chosen by th e user.
Why Do Firms Hire Using Referrals? Evidence from Bangladeshi Garment Factories

I argue that firms use referrals from current workers to mitigate a moral hazard problem. I develop a model in which referrals relax a limited liability constraint by allowing the firm to punish the referral provider if the recipient has low output. I test the model’s predictions using household survey data that I collected in Bangladesh. I can control for correlated wage shocks within a network and correlated unobserved type between the recipient and provider. I reject the testable implications of models in which referrals help firms select unobservably good workers or are solely a nonwage benefit to providers.
Timing evidence in determining the accretion state of the Seyfert galaxy NGC 3783

Previous observations with the Rossi X-ray Timing Explorer (RXTE) have suggested that the power spectral density (PSD) of NGC 3783 flattens to a slope near zero at low frequencies, in a similar manner to that of Galactic black hole X-ray binary systems (GBHs) in the ‘hard’ state. The low radio flux emitted by this object, however, is inconsistent with a hard state interpretation. The accretion rate of NGC 3783 (∼7 per cent of the Eddington rate) is similar to that of other active galactic nuclei (AGN) with ‘soft’-state PSDs and higher than that at which the GBH Cyg X-1, with which AGN are often compared, changes between ‘hard’ and ‘soft’ states (∼2 per cent of the Eddington rate). If NGC 3783 really does have a ‘hard’-state PSD, it would be quite unusual and would indicate that AGN and GBHs are not quite as similar as we currently believe. Here we present an improved X-ray PSD of NGC 3783, spanning from ∼10 −8 to ∼10 −3 Hz, based on considerably extended (5.5 yr) RXTE observations combined with two orbits of continuous observation by XMM‐Newton. We show that this PSD is, in fact, well fitted by a ‘soft’ state model which has only one break, at high frequencies. Although a ‘hard’-state model can also fit the data, the improvement in fit by adding a second break at low frequency is not significant. Thus NGC 3783 is not unusual. These results leave Arakelian 564 as the only AGN which shows a second break at low frequencies, although in that case the very high accretion rate implies a ‘very high’, rather than ‘hard’ state PSD. The break frequency found in NGC 3783 is consistent with the expectation based on comparisons with other AGN and GBHs, given its black hole mass and accretion rate.
NAVI: Neighbor Aware Virtual Infrastructure for Information Dissemination in Vehicular Networks

Vehicular Networks enable a vast number of innovative applications, which rely on the efficient exchange of information between vehicles. However, efficient and reliable data dissemination is a particularly challenging task in the context of vehicular networks due to the underlying properties of these networks, limited availability of network infrastructure and variable penetration rates for distinct communication technologies. This paper presents a novel system and mechanism for information dissemination based on virtual infrastructure selection in combination with multiple communication technologies. The system has been evaluated using a simulation framework, involving network simulation in conjugation with realistic vehicular mobility traces. The presented simulation results show the feasibility of the proposed mechanism to achieve maximum message penetration with reduced overhead. Compared with a cellular-based only solution, our mechanism shows that the judicious vehicle selection can lead to improved network utilization through the offload of traffic to the short-range communication network.
Structure of the Interstellar Medium around Cas A

We present a 3 yr series of observations at 24 μm with the Spitzer Space Telescope of the interstellar material in a 200′ × 200′ square area centered on Cassiopeia A. Interstellar dust heated by the outward light pulse from the supernova explosion emits in the form of compact, moving features. Their sequential outward movements allow us to study the complicated three-dimensional structure of the interstellar medium (ISM) behind and near Cassiopeia A. The ISM consists of sheets and filaments, with many structures on a scale of a parsec or less. The spatial power spectrum of the ISM appears to be similar to that of fractals with a spectral index of 3.5. The filling factor for the small structures above the spatial wavenumber k ∼ 0.5 cycles pc−1 is only ~0.4%.
What is the total number of protein molecules per cell volume? A call to rethink some published values

Novel methods such as mass‐spectrometry enable a view of the proteomes of cells in unprecedented detail. Recently, these efforts have culminated in quantitative measurements of the number of copies per cell for most expressed proteins in organisms ranging from bacteria to mammalian cells. Here, we estimate the expected total number of proteins per unit of cell volume using known parameters related to the composition of cells such as the fraction of cell mass that is protein, and the average protein length. Using simple arguments, we estimate a range of 2–4 million proteins per cubic micron (i.e. 1 fL) in bacteria, yeast, and mammalian cells. Interestingly, we find that measured values that are reported for fission yeast and mammalian cells are often about 3–10 times lower. We discuss this apparent discrepancy and how to use the estimate as benchmark to recalibrate proteome‐wide quantitative censuses or to revisit assumptions about cell composition.
APOE Effects on Default Mode Network in Chinese Cognitive Normal Elderly: Relationship with Clinical Cognitive Performance

Background Functional connectivity in default mode network (DMN) may be changed in Alzheimer’s disease (AD) patients and related risk populations, such as amnestic mild cognitive impairment (aMCI) patients and APOE ε4 carriers. Exploring DMN changes and related behavioral performance of APOE ε4 population might provide valuable evidence for better understanding the development of AD. Methods Subjects were enrolled from a population-based cohort established in a multi-center study in China. Forty-nine cognitive normal individuals were enrolled after standardized cognitive evaluations, MRI examination and APOE genotyping. Regions of interest (ROI)-based functional connectivity analyses were performed, and voxel-based analyses were used to validate these findings. The correlation between DMN functional connectivity and behavioral performance was further evaluated between APOE ε4ε3 and ε3ε3 carriers. Results Comparing to ε3ε3 carriers, functional connectivity between left parahippocampal gyrus and right superior frontal cortex (LPHC-R.Sup.F), left parahippocampal gyrus and medial prefrontal cortex (ventral) (LPHC-vMPFC) were significantly increased in ε4ε3 carriers, while connectivity between cerebellar tonsils and retrosplenial was decreased. LPHC-R.Sup. F connectivity was positively correlated with the changes of delay recall from baseline to follow-up (r = 0.768, p = 0.009), while LPHC-vMPFC connectivity had a positive correlation with MMSE at baseline (r = 0.356, p = 0.018), and a negative correlation with long-delayed recognition at follow-up (r = -0.677, p = 0.031). Significantly increased functional connectivity in vMPFC was confirmed in voxel-based analyses by taking LPHC as seed region. Conclusion APOE ε4 carriers present both increased and decreased functional connectivity in DMN, which is correlated with clinical cognitive performances. DMN changes might be an early sign for cognitive decline.
Several facilities of class diagram generation from two-hemisphere model in the framework of MDA

In Object Management Group model driven architecture models are the primary artifacts during software development, which are presented at the different levels of abstraction from programming details. Class diagram is the most often used model for visual representation of static aspects of software system, but still the formal generation of class diagram from problem domain is under investigation. The paper describes principles of development of class diagram at the conceptual level by using problem domain knowledge presented in the form of two-hemisphere model. Problem domain is presented as two interrelated models of the most important aspects of a system, namely, business process and concept models. Abilities of class diagram generation from two-hemisphere model are presented as a collection of graph transformations and are demonstrated by practical example for abstract problem domain.
Interpreting patient-reported outcomes from clinical trials in COPD: a discussion

One of the challenges faced by the practising physician is the interpretation of patient-reported outcomes (PROs) in clinical trials and the relevance of such data to their patients. This is especially true when caring for patients with progressive diseases such as COPD. In an attempt to incorporate the patient perspective, many clinical trials now include assessments of PROs. These are formalized methods of capturing patient-centered information. Given the importance of PROs in evaluating the potential utility of an intervention for a patient with COPD, it is important that physicians are able to critically interpret (and critique) the results derived from them. Therefore, in this paper, a series of questions is posed for the practising physician to consider when reviewing the treatment effectiveness as assessed by PROs. The focus is on the St George’s Respiratory Questionnaire for worked examples, but the principles apply equally to other symptom-based questionnaires. A number of different ways of presenting PRO data are discussed, including the concept of the minimum clinically important difference, whether there is a ceiling effect to PRO results, and the strengths and weaknesses of responder analyses. Using a worked example, the value of including a placebo arm in a study is illustrated, and the influence of the study on PRO results is considered, in terms of the design, patient withdrawal, and the selection of the study population. For the practising clinician, the most important consideration is the importance of individualization of treatment (and of treatment goals). To inform such treatment, clinicians need to critically review PRO data. The hope is that the questions posed here will help to build a framework for this critical review.
Creating Human-centric Expressive Interfaces : Linking Perceptual evaluations and Engineering Design of Synthetic Multimodal Communication

ix Chapter 1: Introduction 1 1.1 Emotion in Engineering . 1 1.2 Emotion: Definitions, Descriptions, and Quantification . 3 1.2.1 Dimensional Characterization . 4 1.2.2 Categorical Characterization . 4 1.2.3 Emotion Evaluation Structures . 6 1.2. 4 Working Definitions . 7 1.3 Problem Statement and Methods . 7 1.3. 1 Statistical Analyses of Perception . 7 1.3. 2 Emotion Recognition via Emotion Profiling . 8 1.3. 3 Modeling Across Users . 9 1.3. 4 Emotional Data Corpora . 10 1.4 Related work and contributions to this topic . 10 1.4. 1 Related work in the Statistical Analysis of Perception . 10 1.4. 2 Related work in Emotion Recognition . 14 1.5 Open problems and limitations . 19 1.6 Outline of proposal . 21 Chapter 2: Statistical Data Analysis 23 2.1 Motivation for Study . 23 2.2 Audio-Visual Stimuli . 24 2.3 Evaluation Procedure . 25