Miracle-dz/UniFAR-FTUs huggingface dataset:
Bladder Cancer A Multicentre , Randomised Prospective Trial Comparing Three Intravesical Adjuvant Therapies for Intermediate-Risk Superficial Bladder Cancer : Low-Dose Bacillus Calmette-Guerin ( 27 mg ) versus Very Low-Dose Bacillus Calmette-Guerin ( 13 . 5 mg ) versus

Antonio Ojea *, José Luı́s Nogueira , Eduardo Solsona , Nicolás Flores , Jesús Marı́a Fernández Gómez , Jesús Rodrı́guez Molina , Venancio Chantada , José Emilio Camacho , Luı́s Martı́nez Piñeiro , Rafael Hernandez Rodrı́guez , Santiago Isorna , Miguel Blas , José A. Martı́nez-Piñeiro , Rosario Madero , Members of the CUETO Group (Club Urológico Español De Tratamiento Oncológico) Complejo Hospitalario Universitario de Vigo, Vigo, Spain b Instituto Valenciano de Oncologı́a, Valencia, Spain Hospital de Basurto Osakidetza, Bilbao, Spain Complejo Hospitalario de Oviedo, Oviedo, Spain Hospital Clı́nico Universitario San Carlos, Madrid, Spain Hospital Juan Canalejo, La Coruña, Spain Hospital SAS Jerez de la Frontera, Jerez de la Frontera, Spain Hospital la Paz, Madrid, Spain Hospital Universitario Valdecilla, Santander, Spain Hospital Nuestra Señora del Pino, Las Palmas, Spain Hospital Miguel Servet, Zaragoza, Spain Clı́nica La Luz, Madrid, Spain e u r o p e a n u r o l o g y 5 2 ( 2 0 0 7 ) 1 3 9 8 – 1 4 0 6
Culture and Moral Ideologies Of African Americans

This research explores the relationship between culture, measured by the four dimensions of Hofstede's theoretical framework (i.e., collectivism, masculinity, power distance, and uncertainty avoidance), and the two dimensions of personal moral philosophies (i.e., idealism and relativism). A sample of 243 African-American consumers was used to test the relationships between the four independent variables and the two dependent variables. Results confirm that culture affects moral orientations. Specifically, findings suggest a positive relationship between collectivism, uncertainty avoidance, and idealism, and a negative relationship between masculinity and idealism. Results also suggest a positive relationship between collectivism, power distance, uncertainty avoidance, and relativism. Although the study is U. S. based, the results should prove valuable to global marketers because Hofstede's cultural framework allows managers to identify differences in personal moral philosophies of consumers across different cultures and thus provides a theoretical base for designing more effective global marketing strategies.
Music as a cultural identity: a case study of Latino musicians negotiating tradition and innovation in northwest Ohio

This study, based on recent field research, explores Latino music culture in Toledo, Ohio, and presents strategies for incorporating the music into the classroom. In the ethnographic project, three professors - music educator, ethnomusicologist, folklorist - interviewed many musicians, bands and community leaders. Musicians were regenerating Mexican-American traditions, especially that of the folk conjunto ensemble, while developing strategies to innovate the sound and meet the changing aesthetics of a populist youth market and emerging pan-Latino identity. In addition to reconstructing traditional culture, musicians and community leaders were interested in crafting a positive image for both cultural outsiders and insiders and reaching out to the greater Toledo community. The authors highlight the musical lives of the artists, suggest that musicians can play a role in shaping culturally sensitive class curricula, and advocate that educators and students engage directly in fieldwork projects to better grasp the meaning of music in peoples’ lives.
Study Skills, Self-Concept, and Academic Achievement

This study investigated the relationships between study skills, self-concept, and academic achievement and whether the self-report measures contributed to the prediction of grade-point average for 110 university students. Analysis showed that study skills, self-concepts, and academic achievement correlated significantly with each other; rs ranged from . 03 to . 52. In addition to the total study skills score, two measures of study skills (oral reporting and interpersonal relations) and one measure of self-concept (personal self) contributed to the prediction of grade-point average.
Computers and Young Children: Social Benefit or Social Problem?

Using time-diary data from a national sample of young school-age children, we examine the correlates of time spent at home on computing for cognitive and other measures of well-being. We observe modest benefits associated with home computing on three tests of cognitive skill, and on a measure of self-esteem. Most young children who spend time at home on computer-based activities spend no less time on activities such as reading, sports or outside play than children without home computers. However, young children who use home computers a lot, for over 8 hours a week, spend much less time on sports and outdoor activities than non-computer-users. They also have substantially heavier body mass index than children who do not use home computers.
The Effect of Growth Hormone Treatment on Biochemical Indices in Hypophosphatemic Rickets

Background: Growth hormone (GH) in combination with conventional therapy in hypophosphatemic rickets (HR) has been shown to promote renal phosphate (P) conservation and to result in a better metabolic control. This study aimed at investigating the acute biochemical effects of GH in 7 patients (5 female, 2 male) with HR aged between 2.16 and 16 years. Methods: Each patient received the following in a sequential design: oral P plus 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] therapy to determine the optimum doses for baseline requirement followed by GH-only therapy and GH +1,25-(OH)2D3 therapy and GH + P +1,25-(OH)2D3 therapy each for 2 weeks with 1 washout week off treatment in between. GH was given at a dose of 0.03 mg/kg/day s.c. on a daily basis. The dose of oral P used ranged between 500 and 2,000 mg/day, and the dose of 1,25-(OH)2D3 ranged between 0.25 and 0.5 µg/day and was kept constant for each child throughout the study. Results: Laboratory investigations repeated at the end of each treatment, and the first washout period showed that the serum P level was highest (2.9 ng/ml) during the GH + P + 1,25-(OH)2D3 period with higher serum 1,25-(OH)2D3 levels: 50.9 ± (SD) 23.4 ng/l. Parathyroid hormone and alkaline phosphatase levels did not show a significant difference between the periods. The tubular P reabsorbtion rate showed an insignificant increase during GH therapy periods. Conclusion: Considering the fixed dose of P and calcitriol, it may be concluded that GH added to conventional treatment in HR resulted in a slight improvement in the biochemical parameters without any side effects at the short term.
Fairy Tale Femininities: A Discourse Analysis of Snow White Films 1916-2012

Fairy tales are enduring cultural texts that have enjoyed wide appeal and the continuing popularity of the fairy tale can be seen in the recent proliferation of media employing fairy tale narratives. Fairy tales provide a site of meaning about femininity and masculinity and examining them over time identifies versions of gender that are prized or denigrated within specific social, historical moments. This project was interested in the continuities and divergences in these gendered discourses across time. Although there has been considerable academic interest in fairy tales and gender, few studies have approached the topic from a genealogical perspective. This research extends the current literature through a genealogical analysis of five Snow White films from 1916 to 2012 in addition to incorporating an analysis in relation to a contemporary postfeminist, neoliberal social climate. The research employed a feminist poststructuralist framework and utilised thematic and genealogical Foucauldian discourse analysis to analyse the data. Discursive analyses found enduring discourses of traditional femininity across the films which centrally organised around a binary construction of femininity as ‘good’ or ‘bad. ’ A moral discourse worked to construct ‘good’ femininity as prized and bad femininity as punished. Alongside persistent discourses of femininity, however, a newer postfeminist femininity was evident in recent versions of the fairy tale. Consistent with a postfeminist, neoliberal discourse that highlights the importance of the body, analyses found an increased emphasis on beauty and the vast effort required to maintain it. Another postfeminist shift in the tale was the invoking of a girl power discourse to construct Snow as a competent fighter and leader. However, the complex entanglement of discourses of femininity in contemporary society is highlighted by the co-existence of these newer versions of femininity with traditional goals such as achieving a ‘happily ever after. ’ From the perspective of possibilities for subjectivity, these shifts in representation appear to offer a young female audience more empowered possibilities of femininity but such power is simultaneously constrained by a complex amalgamation with traditional ‘niceness’ and beauty.
Increased neutrophil apoptosis in chronic fatigue syndrome

Background/Aims: Many patients with chronic fatigue syndrome (CFS) have symptoms that are consistent with an underlying viral or toxic illness. Because increased neutrophil apoptosis occurs in patients with infection, this study examined whether this phenomenon also occurs in patients with CFS. Methods: Apoptosis was assessed in patients with CFS in conjunction with concentrations of the anti-inflammatory cytokine, transforming growth factor β1 (TGFβ1). Results: The 47 patients with CFS had higher numbers of apoptotic neutrophils, lower numbers of viable neutrophils, increased annexin V binding, and increased expression of the death receptor, tumour necrosis factor receptor-I, on their neutrophils than did the 34 healthy controls. Patients with CFS also had raised concentrations of active TGFβ1 (p < 0.005). Conclusions: These findings provide new evidence that patients with CFS have an underlying detectable abnormality in their immune cells.
Has the Online Discussion Been Manipulated? Quantifying Online Discussion Authenticity within Online Social Media

Online social media (OSM) has a enormous influence in today's world. Some individuals view OSM as fertile ground for abuse and use it to disseminate misinformation and political propaganda, slander competitors, and spread spam. The crowdturfing industry employs large numbers of bots and human workers to manipulate OSM and misrepresent public opinion. The detection of online discussion topics manipulated by OSM \emph{abusers} is an emerging issue attracting significant attention. In this paper, we propose an approach for quantifying the authenticity of online discussions based on the similarity of OSM accounts participating in the discussion to known abusers and legitimate accounts. Our method uses several similarity functions for the analysis and classification of OSM accounts. The proposed methods are demonstrated using Twitter data collected for this study and previously published \emph{Arabic honeypot dataset}. The former includes manually labeled accounts and abusers who participated in crowdturfing platforms. Evaluation of the topic's authenticity, derived from account similarity functions, shows that the suggested approach is effective for discriminating between topics that were strongly promoted by abusers and topics that attracted authentic public interest.
Conductas de riesgo y sintomatología de trastornos del comportamiento alimentario en estudiantes universitarios del Sur de Jalisco, México

The purpose of this research was to estimate the occurrence of risky behaviors and eating disorders symptomatology among undergraduate students from South of Jalisco, Mexico. The sample comprised 143 women with a mean age of 19.90 (SD = 2.14) and 109 men with a mean age of 21.21 (SD= 3.53) who answered the Eating Attitudes Test, the Bulimic Investigatory Test Edinburgh and the Body Shape Questionnaire. The results showed that a higher percentage of women have been on a diet and consumed weight loss products compared with men, who reported to do exercise in order to burn calories. Also, higher percentage of women showed body dissatisfaction (14%) and eating disorders symptomatology (11.9%) in comparison with men (10% and 4.6%, respectively). Women with body dissatisfaction showed a higher number of risky behaviors compared with people without body dissatisfaction. The findings of this research revealed that an important number of undergraduate students from south of Jalisco showed risky behaviors and eating disorders symptomatology.
Media Priming of Presidential and Group Evaluations

Research on media priming largely has been limited to examining the impact of policy issue concerns on evaluations of presidents and other prominent politicians. The goal of this study was to explore the possibility of priming effects in evaluations of political groups, specifically feminists. We conducted an experiment to compare the conditions under which priming of presidential (Clinton) and group (feminists) evaluations was more or less likely to occur. A number of robust and theoretically meaningful priming effects occurred when the president was the target of judgment, these results clarifying and expanding our understanding of principles suggested in earlier scholarship (e.g., involving issue responsibility, issue novelty, political knowledge, and media trust). In contrast, priming of the group evaluations did not occur under any conditions. We conclude with a discussion of when and why priming of group evaluations and priming of presidential evaluations are likely to diverge.
Proximity by design? Affective citizenship and the management of unease

‘Community cohesion’ is the preferred framework for managing ‘race relations’ and ‘conflict’ in contemporary Britain. Initially adopted in government policy following civil disturbances in the summer of 2001, ‘community cohesion’ combined visions of shared belonging with strategies of managing diversity. More recent versions still place a strong emphasis on ideas of shared belonging but these are combined with strategies of managing migration and identity which are deployed in view of securing local communities against threats posed by extremism, deprivation, diversity and feelings of ‘white unease’. This article examines how the community cohesion agenda relies on strategies of governance that seek to design particular kinds of human behaviours such as ‘mixing’ and ‘meaningful interaction’, in view of ‘delivering’ cohesion in the community. I analyse the cohesion agenda as a form of governance that operates through mechanisms of subjectivation. However, instead of privileging the responsible, discerning, rational, autonomous ‘free subject’, I argue that community cohesion is a form of ‘governing through affect’ that draws on and targets the affective subject for certain strategies and regulations aimed at designing people's behaviours and attitudes in the public domain.
LOCKE'S THEORY OF EDUCATION AS A PHILOSOPHICAL ANTHROPOLOGY

My article offers an overview of the role of the theory of education in John Locke’s system of ideas. First and second sections outline main interpretations of Locke’s educational work, from a religious point of view. Important interpretations of John Locke’s work within the framework of history of education are discussed in the third section. In the section that follows, I present my hypothesis on the influence of John Locke’s philosophical anthropology, as described in his educational writing, on his political philosophy. Coherency of Locke’s ideas will be demonstrated at the end of this section on examples from his writings on epistemology, political philosophy, and theology. Locke’s work on education is interpreted as a link between these three fields. In the last section, I present several examples of Locke’s Central-European reception.
Feline Immunodeficiency Virus (FIV) Neutralization: A Review

One of the major obstacles that must be overcome in the design of effective lentiviral vaccines is the ability of lentiviruses to evolve in order to escape from neutralizing antibodies. The primary target for neutralizing antibodies is the highly variable viral envelope glycoprotein (Env), a glycoprotein that is essential for viral entry and comprises both variable and conserved regions. As a result of the complex trimeric nature of Env, there is steric hindrance of conserved epitopes required for receptor binding so that these are not accessible to antibodies. Instead, the humoral response is targeted towards decoy immunodominant epitopes on variable domains such as the third hypervariable loop (V3) of Env. For feline immunodeficiency virus (FIV), as well as the related human immunodeficiency virus-1 (HIV-1), little is known about the factors that lead to the development of broadly neutralizing antibodies. In cats infected with FIV and patients infected with HIV-1, only rarely are plasma samples found that contain antibodies capable of neutralizing isolates from other clades. In this review we examine the neutralizing response to FIV, comparing and contrasting with the response to HIV. We ask whether broadly neutralizing antibodies are induced by FIV infection and discuss the comparative value of studies of neutralizing antibodies in FIV infection for the development of more effective vaccine strategies against lentiviral infections in general, including HIV-1.
Metarouting Timothy

There is a shortage of routing protocols that meet the needs of network engineers. This has led to BGP being pressed into service as an IGP, despite its lack of convergence guarantees. The development, standardization, and deployment of routing protocols, or even minor changes to existing protocols, are very difficult tasks. We present an approach called Metarouting that defines routing protocols using a high-level and declarative language. Once an interpreter for a metarouting language is implemented on a router, a network operator would have the freedom to implement and use any routing protocol definable in the language. We enforce a clean separation of protocol mechanisms (link-state, path-vector, adjacency maintenance, and so on) from routing policy (how routes are described and compared). The Routing Algebra framework of Sobrinho [25] is used as the theoretical basis for routing policy languages. We define the Routing Algebra Meta-Language (RAML) that allows for the construction of a large family of routing algebras and has the key property that correctness conditions — guarantees of convergence with respect to the chosen mechanisms — can be derived automatically for each expression defining a new routing algebra.
Serum Proteomics in Dementia : Discovery and Validation of Biomarkers

textabstractDementia is a syndrome due to disease of the brain, usually of a chronic or progressive nature, in which there is disturbance of multiple higher cortical functions, including memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgement. Consciousness is not clouded. The impairments of cognitive function are commonly accompanied, and occasionally preceded, by deterioration in emotional control, social behaviour, or motivation. This syndrome occurs in Alzheimer’s disease, in cerebrovascular disease, and in other conditions primarily or secondarily affecting the brain (World Health Organization’s International Classification of Diseases (ICD-10, version 2007)). It is estimated that there are currently 35.6 million people with dementia around the world and that this number will nearly double every 20 years, to 65.7 million in 2030 and 115.4 million in 2050. Dementia mainly affects the elderly; after 65 years of age the prevalence doubles with every five-year increase in age. The most common types of dementia are Alzheimer’s disease (AD; 50-70%), vascular dementia (VaD; 20-30%), frontotemporal dementia (5- 10%) and dementia with Lewy bodies (<5%)1. The borders between the different types are not at all strict, most of the times a mix of various types is observed. This is particularly true for AD and VaD, and AD and dementia with Lewy bodies. In a large autopsy study of 1050 elderly demented individuals, 86% had AD related pathology. From this percentage only 43% had pure AD, 23% had mixed AD and VaD and 11% had AD with Lewy bodies.
A Constant Spectral Index for Sagittarius A* during Infrared/X-Ray Intensity Variations

We report the first time series of broadband infrared color measurements of Sgr A*, the variable emission source associated with the supermassive black hole at the Galactic center. Using the laser and natural guide star adaptive optics systems on the Keck II Telescope, we imaged Sgr A* in multiple near-infrared broadband filters with a typical cycle time of ~3 minutes during four observing runs (2005-2006), two of which were simultaneous with Chandra X-ray measurements. In spite of the large range of dereddened flux densities for Sgr A* (2-30 mJy), all of our near-infrared measurements are consistent with a constant spectral index of α = -0.6 ± 0.2 (Fν ∝ να). Furthermore, this value is consistent with the spectral indices observed at X-ray wavelengths during nearly all outbursts, which is consistent with the synchrotron self-Compton model for the production of the X-ray emission. During the coordinated observations, one infrared outburst occurs ≤36 minutes after a possibly associated X-ray outburst, while several similar infrared outbursts show no elevated X-ray emission. A variable X-ray to IR ratio and constant infrared spectral index challenges the notion that the infrared and X-ray emission are connected to the same electrons. We, therefore, posit that the population of electrons responsible for both the IR and X-ray emission are generated by an acceleration mechanism that leaves the bulk of the electron energy distribution responsible for the infrared emission unchanged, but has a variable high-energy cutoff. Occasionally a tail of electrons ≳1 GeV is generated, and it is this high-energy tail that gives rise to the X-ray outbursts. One possible explanation for this type of variation is from the turbulence induced by a magnetorotational instability, in which the outer scale length of the turbulence varies and changes the high-energy cutoff.
Diversity in Romantic Relations of Adolescents with Varying Health Status

In a longitudinal study on adolescents varying in health status, the similarities and differences between adolescents’ close friendships and romantic relationships were analyzed. From a total of 91 diabetic and 107 healthy adolescents, a subsample of 95 adolescents who consistently had experiences with both relationships over 4 years was drawn. Information was obtained from semistructured interviews and the Network of Relationship Inventory. The results demonstrated important time-dependent links between intimacy in both relationship types in healthy adolescents. Despite considerable gains in intimacy toward close friends and romantic partners across time, diabetic adolescents did not focus as much on intimacy in their romantic relations as their healthy peers did but looked for romantic partners who could offer them security, support, and assistance in a stable relationship. Results emphasize that although intimacy with close friends is a normative precursor of later romantic relationships, there is still not a single path for romantic development.