Miracle-dz/UniFAR-FTUs huggingface dataset:
Consumer education: creating consumer awareness among adolescents in Botswana

Senior secondary schools’ students in Botswana were studied to determine their awareness of consumer rights and responsibilities and their perceptions of consumer behaviour and consumer education. Recommendations will inform the refinement of consumer education teaching in Botswana as well as other secondary education programmes. A questionnaire suitable for this study was used to collect data. Responses from 3107 students were received. Descriptive statistical analysis was used to determine frequencies and central tendencies. Chi-square tests were computed to examine relationships among variables by gender, class level, and school location. Two-thirds of the students correctly identified consumer rights and responsibilities. Female students were more likely to identify consumer rights and responsibilities than males. Students agreed that they were informed on consumer issues and females were more likely to be informed than males. Topics identified to be taught in consumer education included consumer rights and responsibilities, purchasing decisions, advertising and others. The delivery methods identified were classes in school, workshops, radio and television programmes, and consumer youth clubs. Consumer education programmes were found to have an impact on adolescents because most of them were aware of consumer rights and responsibilities and acted as informed consumers on most consumer issues.
Chemoprevention of Head and Neck Cancer with Celecoxib and Erlotinib: Results of a Phase Ib and Pharmacokinetic Study

Epidermal growth factor receptor (EGFR) and COX-2 inhibitors synergistically inhibit head and neck squamous cell carcinoma tumorigenesis in preclinical studies. We conducted a phase I and pharmacokinetic study with the erlotinib and celecoxib combination in patients with advanced premalignant lesions. Thirty-six subjects with oral leukoplakia, mild, moderate, or severe dysplasia, or carcinoma in situ were screened for study participation; 12 consented and received therapy for a median of 5.38 months. Erlotinib was escalated following a standard 3+3 design at 50, 75, and 100 mg orally daily and celecoxib was fixed at 400 mg twice daily for 6 months. Biopsy of lesions and cytobrush of normal mucosa were performed at baseline, 3, 6, and 12 months. Erlotinib pharmacokinetics were analyzed in 10 subjects. The maximum tolerated dose of erlotinib with celecoxib 400 mg BID was 50 mg per day with skin rash being the main observed toxicity. Overall histologic response rate was 63% (complete response, 43%; partial response, 14%; stable disease, 29%; and disease progression, 14%). With median follow-up of 36 months, mean time to progression to higher-grade dysplasia or carcinoma was 25.4 months. Downregulation of EGFR and p-ERK in follow-up biopsies correlated with response to treatment. Larger average erlotinib V/F (approximately 308 L) and CL/F (8.3 L/h) compared with previous studies may be related to relatively large average bodyweights. Average erlotinib t1/2 was 25.6 hours. Encouraging responses to the celecoxib and erlotinib combination correlated with EGFR pathway inhibition. Although erlotinib-related rash was the main limitation to dose escalation, the intervention was well tolerated. Cancer Prev Res; 7(3); 283–91. ©2013 AACR.
Continuous action segmentation and recognition using hybrid convolutional neural network-hidden Markov model model

Continuous action recognition in video is more complicated compared with traditional isolated action recognition. Besides the high variability of postures and appearances of each action, the complex temporal dynamics of continuous action makes this problem challenging. In this study, the authors propose a hierarchical framework combining convolutional neural network (CNN) and hidden Markov model (HMM), which recognises and segments continuous actions simultaneously. The authors utilise the CNN's powerful capacity of learning high level features directly from raw data, and use it to extract effective and robust action features. The HMM is used to model the statistical dependences over adjacent sub-actions and infer the action sequences. In order to combine the advantages of these two models, the hybrid architecture of CNN-HMM is built. The Gaussian mixture model is replaced by CNN to model the emission distribution of HMM. The CNN-HMM model is trained using embedded Viterbi algorithm, and the data used to train CNN are labelled by forced alignment. The authors test their method on two public action dataset Weizmann and KTH. Experimental results show that the authors’ method achieves improved recognition and segmentation accuracy compared with several other methods. The superior property of features learnt by CNN is also illustrated.
Enhanced biological activities of gamma-irradiated persimmon leaf extract

Abstract The aim of this study was to compare the anti-oxidative and anti-inflammatory activities of gamma-irradiated persimmon leaf extract (GPLE) with those of non-irradiated persimmon leaf extract (PLE). Ethanolic extract of persimmon leaf was exposed to gamma irradiation at a dose of 10 kGy. After gamma irradiation, the color of the extract changed from dark brown to light brown. The anti-oxidative and anti-inflammatory activities of GPLE and PLE were assessed from: total polyphenol and total flavonoid contents; 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assay, and levels of pro-inflammatory mediators such as nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6). The total polyphenol contents of GPLE and PLE were determined to be 224.44 ± 1.54 and 197.33 ± 5.81 mg gallic acid equivalents (GAE)/g, respectively, and the total flavonoid contents of GPLE and PLE were 206.27 ± 1.15 and 167.60 ± 2.00 mg quercetin equivalents (QUE)/g, respectively. The anti-oxidant activities of GPLE and PLE as measured by DPPH assays were 338.33 ± 30.19 μg/ml (IC50) and 388.68 ± 8.45 μg/ml (IC50), respectively, and those measured by ABTS assays were 510.49 ± 15.12 μg/ml (IC50) and 731.30 ± 10.63 μg/ml (IC50), respectively. IC50 is the inhibitor concentration that reduces the response by 50%. GPLE strongly inhibited the production of NO, PGE2 and IL-6 compared with PLE in lipopolysaccharide-stimulated RAW264.7 macrophages. Furthermore, GPLE significantly inhibited the production of TNF-α and IL-6 cytokines compared with PLE in phorbol 12-myristate 13-acetate (PMA) plus A23187-stimulated HMC-1 human mast cells. These results indicate that gamma irradiation of PLE can enhance its anti-oxidative and anti-inflammatory activities through elevation of the phenolic contents. Therefore, gamma-irradiated PLE has potential for use in the food and cosmetic industries.
Asymmetric industry structures : multiple technologies, firm dynamics and profitability

The origins of asymmetric firm sizes are analyzed in the first part of this thesis, modelling technology choice in a one shot quantity game with homogeneous goods. For certain sizes of the market more than one technology is chosen in equilibrium. Generally, the larger the market, the higher the fixed cost of the technology that is chosen in equilibrium. The trade off between market size and concentration is non-monotonic, even if for any size of the market only the most fragmented market structure is considered. In the second part consequences of asymmetric firm sizes are investigated. In Chapter 3 firm dynamics in the chemical sector are examined, distinguishing between the dynamics of scale and scope. The production capacity of firms in homogeneous bulk chemical markets converges in size on a market by market basis, resulting in a fragmented industry structure on a disaggregated level. However, the number of products chemical corporations produce within a category of (synthetic organic) chemicals diverges, leading to a more concentrated industry structure on higher levels of aggregation. These counteracting forces can potentially explain the persistence of concentration that has been observed in fast growing chemical markets. In Chapter 4 it is shown that if the observed asymmetry between firms is consistent with a (subgame-perfect) equilibrium of some single or multi-stage game, bounds exist that restrict the degree of asymmetry between the firms' profitability. Their shape is determined by industry factors. In particular, a higher sensitivity of a firm's profitability on its competitor's action rotates the bounds on the profitability-size trade off anti-clockwise. This is tested for homogeneous goods industries using a panel from the FTC Line of Business Data. Allowing for firm specific fixed effects, some strong empirical support is found.
Why Does Poor Performance Get so Much Attention in Public Policy?

Abstract: This article explores why information on poor performance often gets most of the attention in public policy. In order to illustrate the discussion this paper analyses the case of educational policy for secondary schools in Norway, and in particular the policy of participating in the OECD Programme for International Student Assessment (PISA) which measures educational outcomes for 15‐year old pupils regarding reading, mathematics and science. Governments, researchers, interest groups and the media await the regular release of the PISA results every third year with great interest, and participate in the strategy of ‘naming and blaming’ based on the relative national performances. The practice of identifying poor performance and the subsequent public discourses has become an institution. Despite the negativity‐bias the strategic use of information associated with these processes may have positive impacts on decision making, policy innovation and democratic accountability.
Voluntary fair value disclosures beyond SFAS 157’s three-level estimates

Some firms voluntarily make disclosures about the controls and processes in place to ensure the reliability of fair value estimates. Consistent with these disclosures being driven by investors’ concerns about the reliability of their SFAS 157 estimates, we find that firms with more opaque estimates are more likely to provide such disclosures. We then examine whether these disclosures improve investors’ perception about the reliability of fair value estimates. We find that they are associated with higher market pricing and lower information risk for Level 3 estimates. Further analyses of the disclosures reveal that the following types of information are particularly important to investors: discussion of the external and independent pricing of fair value estimates and their proper classification according to the SFAS 157 hierarchy. Overall, our results suggest that the voluntary reliability disclosures that firms provide beyond SFAS 157’s three-level estimates help reduce investors’ uncertainty toward the more opaque fair value estimates.
GMACE Weighting Factors

Statistical indicators to quantify information in national GEBV are required for optimal weighting of these GEBV as input observations for GMACE. The weighting factors are also used when approximating reliabilities of GMACE output, the international GEBV. The present study considered a change in approach from providing a recipe to national centers for deriving the weighting factors, to instead having Interbull apply the recipe internally and in a guaranteed consistent way for all countries. The main impacts of this change in approach were on selected estimates of genomic variance and GMACE reliabilities, most notably for specific estimates that had previously been questioned as erroneous. Most estimates of variance and reliability were essentially unaffected by the change in approach, because most weighting factors were only slightly different than before. An advantage of the new approach was that weighting factors and GMACE model specifics became perfectly aligned, and thus GMACE reliabilities were aligned without exception to the national values. All GMACE reliabilities were equal or higher than national values. All increases in reliability with GMACE were as expected, only for bulls that had input GEBV from more than one country, and with smaller increases if the multiple GEBV were from countries that share data for national genomic predictions.
Orphan Volunteer Tourism in Thailand: Volunteer Tourists’ Motivations And On-Site Experiences

This study examines motivations and on-site experiences of volunteer tourists who participate in volunteer tourism at the Home and Life Orphanage in Phang Nga province, Thailand. An interpretive paradigm using qualitative data collection methods (semi-structured interviews, a focus group, participant observation, and diaries) was adopted. The informants included 24 volunteer tourists. The findings of the study suggest that the volunteer tourists’ motivations and on-site experiences are multidimensional. Five main themes of motivations have been identified: (a) to help the children who were affected by the 2004 Boxing Day tsunami, (b) to gain personal development and growth, (c) to gain new experiences, (d) to learn about/be immersed in local culture, and (e) to meet and make friends. In terms of the volunteer tourists’ on-site experiences, four experiential dimensions were found: (a) personal development and growth, (b) social, (c) cultural, and (d) feeling.
Four Simple Tests of Campaign Contributions and Trade Policy Preferences

This paper uses campaign contribution data to examine trade policy preferences among political action committees. With perfect factor mobility, as the Heckscher-Ohlin (HO) model assumes, interest group trade positions should depend on their factor of production but not on their industry. We show, consistent with the 2 × 2 HO model, that capital groups consistently back representatives supporting trade liberalization while labor groups favor protectionists. Unlike previous work, we also measure the variation in trade policy preferences within capital and labor groups. We find evidence that the industry net export position significantly affects labor unions' trade policy preferences. Industry characteristics have no impact on capital group lobbying. The former result suggests that empirical analyses of labor PAC contributions that exclude industry characteristics may be misspecified. Copyright Blackwell Publishing Ltd 2004.
Study of sperm concentration, seminal plasma composition and their physiological correlation in the Persian sturgeon, Acipenser persicus.

The objectives of the present study were to determine ionic and organic composition of seminal plasma, sperm concentration and their relationships in the Persian sturgeon (Acipenser persicus). In this regard, ionic content (Na(+) , K(+) , Cl(-) , Ca(2+) and Mg(2+) ) and organic content (total protein, glucose, cholesterol and triglyceride) along with sperm concentration were measured in 17 specimens of the Persian sturgeon. The seminal plasma contained 59.53 ± 2.56 mm/l sodium, 9.1 ± 1.42 mm chloride, 4.72 ± 0.3 mm potassium, 1.45 ± 0.075 mm calcium and 0.7 ± 0.072 mm magnesium. The following organic contents were found: total protein 0.11 ± 0.02 g/dl, glucose 22.18 ± 4.16 mg/dl, cholesterol 6.67 ± 1.04 mg/dl and triglyceride 15.2 ± 0.65 mg/dl. The mean sperm concentration was estimated to be 1.6 ± 0.12 (×10(9) sperm/ml). A significant relationship was found between sperm concentration and K(+) of seminal plasma (r = 0.533, p < 0.05). Significant correlations were observed between ionic contents: Na(+) vs Cl(-) (r = -0.854, p < 0.01) and Mg(2+) vs K(+) (-0.583, p < 0.05). Also, level of triglyceride was negatively correlated with Mg(2+) (r = -0.503, p < 0.05). Presented data could be considered as a complementary study for developing special extenders and protectant solutions for improving artificial fertilization in this valuable species.
Size-dependent neural integration between genetically different colonies of a marine bryozoan

Although the formation of genetic chimeras is rare in the animal kingdom, it has long been known that colonial marine invertebrates fuse under natural conditions, forming genetic chimeras. I report here an example of selective, partial fusion. When small colonies of the encrusting marine bryozoan Membranipora membranacea grow into contact, they usually become behaviorally coordinated: if one colony is disturbed, both colonies will simultaneously retract their feeding structures (lophophores). As a first step towards understanding the fitness consequences of this type of apparent fusion, I examine its mechanistic basis. Using assays of zooid behavior, electrophysiological recordings and 14C-labeled metabolites, I demonstrate that physiological integration between M. membranacea colonies is both partial and temporary. Specifically, this study demonstrates (1) that behavioral coordination is the result of neural integration between colonies, (2) that coordinated colony pairs do not exchange metabolites, and (3) that neural integration is a temporary phenomenon that is terminated as colonies grow larger. Additionally, I show that only those zooids at the middle of the intercolony border mediate neural integration. Partial physiological integration between M. membranacea colonies could be a highly specific interaction that increases the potential benefits of fusion (i.e. neural integration) while minimizing the potential costs (i.e. resource parasitism).
Short-term effects of radiofrequency shrinkage treatment for anterior cruciate ligament relaxation on proprioception

Objective Radiofrequency (RF) shrinkage is used in anterior cruciate ligament (ACL) reconstruction. The present study investigated the therapeutic effects of RF on ACL relaxation and the probable influencing factors. Methods Patients with ACL relaxation were included. Participants were randomly divided into two groups: a treatment group, in which patients were treated with RF shrinkage (RF group); a control group, in which patients received conventional surgical treatment. Thermal shrinkage was performed on ACL using an ArthroCare® CAPSure® wand. Lysholm scores, proprioceptive testing and Tegner activity scores were evaluated before and after treatment (at 6 and 12 months). Results A total of 38 patients were included. The mean ± SD Lysholm score of those in the RF group at 12 months’ post-treatment was significantly higher than in controls. The angle of deviation of the knee joint in RF group was significantly larger than in the control group at 6 months’ post-treatment. Conclusions RF shrinkage treatment for ACL laxity could improve knee scores, and may affect proprioception and recovery of activity after surgery.
A prospective evaluation of radiocolloid and immunohistochemical staining in colon carcinoma lymphatic mapping

Although the utility of lymphatic mapping (LM) and sentinel lymph node (SLN) biopsy in patients with melanoma and breast carcinoma has been well documented, this same is not true for patients with colon carcinoma. The authors previously reported a high false‐negative rate for SLN biopsy in patients with colon carcinoma using isosulfan blue dye alone. The objective of the current study was to determine whether radiocolloid would increase the sensitivity of LM/SLN biopsy in patients with colon carcinoma.
Small Firm Finance, Credit Rationing, and the Impact of SBA‐Guaranteed Lending on Local Economic Growth

Increasingly, policymakers look to the small business sector as a potential engine of economic growth. Policies to promote small businesses include tax relief, direct subsidies, and indirect subsidies through government lending programs. Encouraging lending to small business is the primary policy objective of the Small Business Administration (SBA) loan‐guarantee program. Using a panel data set of SBA‐guaranteed loans, we assess whether or not SBA‐guaranteed lending has an observable impact on local economic performance. We find a positive and significant (although economically small) relationship between the relative levels of SBA‐guaranteed lending in a local market and the future per capita income growth in that market.
Species-specificity of nurse plants for the establishment, survivorship, and growth of a columnar cactus.

UNLABELLED PREMISE OF THE STUDY Seedling establishment and early survivorship are crucial steps for the regeneration of plant populations because both have long-lasting effects on plant population dynamics. For species recruiting through facilitation, species-specific facilitative effects might affect early fitness, an overlooked aspect in studies of facilitation considering groups of nurse species. • METHODS We experimentally evaluated the roles of 10 nurse species and open space on the early performance of the columnar cactus Neobuxbaumia mezcalaensis. We measured establishment, survivorship, and growth of individuals over 3 years. Moreover, to study an extended period of the ontogeny of the interaction between this cactus and its nurse plants, we also monitored survivorship and growth rates of individuals between 3 to 12 cm tall during a 3-year period. • KEY RESULTS Neobuxbaumia mezcalaensis performance varied significantly among nurse species, and only six yielded positive effects on early fitness. Densely canopied plants were the best nurses for this cactus. However, even among densely canopied species, some produced negative effects on the early fitness of N. mezcalaensis, indicating that similar nurse plants may elicit either facilitative or interference effects on beneficiary species. • CONCLUSIONS Our results emphasize the importance of species-specific facilitative interactions in the crucial early stages in the life cycle of N. mezcalaensis and how different nurse species modify the effect of seed-rain and contribute significantly to the population dynamics of the species.
Attitudes to a Non-viable Community-owned Heritage Tourist Attraction

This paper reports on a study of community attitudes to a publicly owned heritage tourism attraction in a regional Australian centre. The attraction, an authentic reproduction of a 19th-century riverboat, was built as an Australian bicentennial project in 1988, with the aim of her becoming the region's primary tourism attraction. However, over the years it has proved to be a non-viable attraction, requiring an ongoing council subsidy of up to $A200,000 per year to keep it operational. The council is under strong pressure to divest itself of the vessel, which will mean its closure and likely removal from the community. The study found strong support for council retention and continued subsidisation of its operations. However, the study also raises questions about the efficacy of community involvement in the decision-making process. In this instance, emotional attachment to the attraction, rather than a rational assessment of its future, drives community attitudes.
Periodic paralysis complicating thyrotoxicosis in Chinese.

In Europe and the United States of America periodic paralysis would appear to be a rare complication of thyrotoxicosis. In contrast, in Japan this complication has been reported to occur in some 2% of all thyrotoxic patients, consequently 90% of the case reports in the literature have comefrom Japan (Engel, 1961). Before the investigation which is the subject of this communication was made it was apparent to us that periodic paralysis also commonly complicated thyrotoxicosis in the Chinese, yet, strangely, this had not been reported in the literature. Indeed, up to the present there has been but one report of its occurrence in a Chinese in Taiwan (Chen, Hung, and Lin, 1965).