Miracle-dz/UniFAR-FTUs huggingface dataset:
A Study of Sigma Phase Evolution in Long-Term Creep Tested Super 304H Samples

Due to their excellent high temperature oxidation resistance, utilities worldwide are adopting advanced austenitic stainless steels (A-ASS) for critical plant components, such as heat exchangers, as they aim to achieve higher operating conditions. However, challenges may be encountered in developing life assessment and life management strategies for such components. This is because conventional methods used for life assessment, such as measuring steam side oxide scale thickness in ferritic and conventional austenitic material to predict tube metal temperature, may not be successfully applied to A-ASS. In such instances, tracking the formation and evolution of microstructural features during service, may offer a possible method to predict the temperature of these steels. For such metallurgy based lifing strategy to be successful, it is essential to develop a good understanding of microstructure evolution in these steels. In this work one heat of Super 304H, that has been creep tested at 600°C, 650°C and 700°C, with applied stress ranging from 110 to 340 MPa, is characterized using a combination of advanced characterization tools and image analysis methods. The amount of sigma phase formed at the gauge and grip sections of the samples is quantified and the methodology used to quantify this phase is presented. From the results, a time-temperature-transformation diagram for sigma formation is developed.
Abolishing Fees at Health Centers in the Context of Community Case Management of Malaria: What Effects on Treatment-Seeking Practices for Febrile Children in Rural Burkina Faso?

Introduction Burkina Faso started nationwide community case management of malaria (CCMm) in 2010. In 2011, health center user fees for children under five were abolished in some districts. Objective To assess the effects of concurrent implementation of CCMm and user fees abolition on treatment-seeking practices for febrile children. Methods This is a natural experiment conducted in the districts of Kaya (CCMm plus user fees abolition) and Zorgho (CCMm only). Registry data from 2005 to 2014 on visits for malaria were collected from all eight rural health centers in the study area. Annual household surveys were administered during malaria transmission season in 2011 and 2012 in 1,035 randomly selected rural households. Interrupted time series models were fitted for registry data and Fine and Gray’s competing risks models for survey data. Results User fees abolition in Kaya significantly increased health center use by eligible children with malaria (incidence rate ratio for intercept change = 2.1, p <0.001). In 2011, in Kaya, likelihood of health center use for febrile children was three times higher and CHW use three times lower when caregivers knew services were free. Among the 421 children with fever in 2012, the delay before visiting a health center was significantly shorter in Kaya than in Zorgho (1.46 versus 1.79 days, p <0.05). Likelihood of visiting a health center on the first day of fever among households <2.5km or <5 km from a health center was two and three times higher in Kaya than in Zorgho, respectively (p <0.001). Conclusions User fees abolition reduced visit delay for febrile children living close to health centers. It also increased demand for and use of health center for children with malaria. Concurrently, demand for CHWs’ services diminished. User fees abolition and CCMm should be coordinated to maximize prompt access to treatment in rural areas.
How to Make an Image More Memorable?: A Deep Style Transfer Approach

Recent works have shown that it is possible to automatically predict intrinsic image properties like memorability. In this paper, we take a step forward addressing the question: "Can we make an image more memorable? ". Methods for automatically increasing image memorability would have an impact in many application fields like education, gaming or advertising. Our work is inspired by the popular editing-by-applying-filters paradigm adopted in photo editing applications, like Instagram and Prisma. In this context, the problem of increasing image memorability maps to that of retrieving ``memorabilizing'' filters or style ``seeds''. Still, users generally have to go through most of the available filters before finding the desired solution, thus turning the editing process into a resource and time consuming task. In this work, we show that it is possible to automatically retrieve the best style seeds for a given image, thus remarkably reducing the number of human attempts needed to find a good match. Our approach leverages from recent advances in the field of image synthesis and adopts a deep architecture for generating a memorable picture from a given input image and a style seed. Importantly, to automatically select the best style a novel learning-based solution, also relying on deep models, is proposed. Our experimental evaluation, conducted on publicly available benchmarks, demonstrates the effectiveness of the proposed approach for generating memorable images through automatic style seed selection.
Uniportal video assisted thoracoscopic lobectomy: primary experience from an Eastern center.

BACKGROUND Uniportal video-assisted thoracoscopic surgery (VATS) lobectomy is an emerging technique for the surgical resection of non-small cell lung cancer (NSCLC). Besides its wide debates on safety and efficacy throughout the world, there were few report on uniportal VATS from the Eastern countries. In this article, we summarized our primary experience on uniportal VATS lobectomy in an Eastern center. METHODS From October 2013 till February 2014, 54 consecutive uniportal VATS lobectomy were performed in the Department of Thoracic Surgery, Zhongshan Hospital of Fudan University. Patients' clinical features and operative details were recorded. Post-operatively, the morbidity and mortality were recorded to analyze the safety and efficacy of uniportal VATS lobectomy for NSCLCs. RESULTS Among the 54 planned uniportal VATS lobectomy, there was one conversion to mini-thoracotomy due to lymph node sticking. Extra ports were required in two patients. The uniportal VATS lobectomy was achieved in 51 out of 54 patients (94.4%). The average operation duration was 122.2±37.5 min (90-160 min). The average volume of estimated blood loss during the operation was 88.8±47.1 mL (50-200 mL). The mean chest tube duration and hospital stay were 3.2±1.9 days and 4.6±2.0 days, respectively. There was no postoperative mortality in this study. Two patients suffered from prolonged air leakage (5 and 7 days), and one atrial fibrillation was observed in this cohort. CONCLUSIONS Based on our primary experience, uniportal VATS lobectomy is a safe and effective procedure for the surgical resection of NSCLCs. The surgical refinements and instrumental improvements would facilitate the technique. Further studies based on larger population are required to determine its benefits towards patients with NSCLCs.
On graph crossing number and edge planarization

Given an <i>n</i>-vertex graph <i>G</i>, a <i>drawing</i> of <i>G</i> in the plane is a mapping of its vertices into points of the plane, and its edges into continuous curves, connecting the images of their endpoints. A <i>crossing</i> in such a drawing is a point where two such curves intersect. In the Minimum Crossing Number problem, the goal is to find a drawing of <i>G</i> with minimum number of crossings. The value of the optimal solution, denoted by OPT, is called the graph's <i>crossing number</i>. This is a very basic problem in topological graph theory, that has received a significant amount of attention, but is still poorly understood algorithmically. The best currently known efficient algorithm produces drawings with <i>O</i>(log<sup>2</sup> <i>n</i>)·(<i>n</i> + OPT) crossings on bounded-degree graphs, while only a constant factor hardness of approximation is known. A closely related problem is Minimum Planarization, in which the goal is to remove a minimum-cardinality subset of edges from <i>G</i>, such that the remaining graph is planar. Our main technical result establishes the following connection between the two problems: if we are given a solution of cost <i>k</i> to the Minimum Planarization problem on graph <i>G</i>, then we can efficiently find a drawing of <i>G</i> with at most poly(<i>d</i>) · <i>k</i> · (<i>k</i> + OPT) crossings, where <i>d</i> is the maximum degree in <i>G. </i> This result implies an <i>O</i>(<i>n</i> · poly(<i>d</i>) · log<sup>3/2</sup> <i>n</i>)-approximation for Minimum Crossing Number, as well as improved algorithms for special cases of the problem, such as, for example, <i>k</i>-apex and bounded-genus graphs.
Characterization of a Flexible UWB Sensor for Indoor Localization

This paper presents research to develop an ultrawideband ranging sensor for personnel indoor localization based on the measurement of the pulse round-trip time. An approach combining flexibility, a high measurement update rate, and asynchronous operation with digital processing capability has been employed in the design of the sensor. The principle of operation, the architecture of the realized sensor, and the experimental setup are described. Finally, the results of a ranging calibration and validation test are presented and discussed. In the validation procedure, a root-mean-square error of 29 cm and a maximum absolute error of 81 cm with an operational range of approximately 10 m were observed.
LINEARIZATIONS OF SINGULAR MATRIX POLYNOMIALS AND THE RECOVERY OF MINIMAL INDICES

A standard way of dealing with a regular matrix polynomial P (λ) is to convert it into an equivalent matrix pencil - a process known as linearization. Two vector spaces of pencils L1(P ) and L2(P ) that generalize the first and second companion forms have recently been introduced by Mackey, Mackey, Mehl and Mehrmann. Almost all of these pencils are linearizations for P (λ )w hen P is regular. The goal of this work is to show that most of the pencils in L1(P )a ndL2(P )a re stil l linearizations when P (λ) is a singular square matrix polynomial, and that these linearizations can be used to obtain the complete eigenstructure of P (λ), comprised not only of the finite and infinite eigenvalues, but also for singular polynomials of the left and right minimal indices and minimal bases. We show explicitly how to recover the minimal indices and bases of the polynomial P (λ )f rom the minimalindices and bases of l in L1(P )a ndL2(P ). As a consequence of the recovery formulae for minimal indices, we prove that the vector space DL(P )= L1(P ) ∩ L2(P )w il l never contain any linearization for a square singular polynomial P (λ). Finally, the results are extended to other linearizations of singular polynomials defined in terms of more general polynomial bases.
Smoothed Particle Hydrodynamics Coupled with Radiation Transfer

We have been constructed a brand-new radiation hydrodynamics solver based upon Smoothed Particle Hydrodynamics (SPH), which works on parallel computer system. The code is designed to investigate the formation and evolution of the first generation objects at $z \gtrsim 10$, where the radiative feedback from various sources play important roles. The code can compute the fraction of chemical species e, H$^+$, H, H$^-$, H$_2$, and H$_2^+$ by fully implicit time integration. It also can deal with multiple sources of ionizing radiation, as well as the radiation at Lyman-Werner band. We compare the results for a few test calculations with the results of one dimensional simulations, in which we find good agreements with each other. We also evaluate the speedup by parallelization, that is found to be almost ideal, as far as the number of sources is comparable to the number of processors.
Quantitative study of KI‐67 antibody staining in 46 T‐cell malignant lymphomas using image analysis

Image analysis with a SAMBA 2005 (ALCATEL‐TITN, Co) was used to quantify the Ki‐67 stained area percentage in 46 T‐cell malignant lymphomas (T‐ML), classified according to the updated Kiel classification. This parameter demonstrated correlation with the number of Ki‐67‐positive cellular profiles (r = 0.88, P < 0.001) and was more reproducible than cell counting.
Bycatch of Marine Mammals in U.S. and Global Fisheries

Abstract: Fisheries bycatch poses a significant threat to many populations of marine mammals, but there are few published estimates of the magnitude of these catches. We estimated marine mammal bycatch in U.S. fisheries from 1990 to 1999 with data taken from the stock assessment reports required by the U.S. Marine Mammal Protection Act. The mean annual bycatch of marine mammals during this period was 6215 ± 448 (SE). Bycatch of cetaceans and pinnipeds occurred in similar numbers. Most cetacean (84%) and pinniped (98%) bycatch occurred in gill‐net fisheries. Marine mammal bycatch declined significantly over the decade, primarily because of a reduction in the bycatch of cetaceans. Total marine mammal bycatch was significantly lower after the implementation of take reduction measures in the latter half of the decade. We derived a crude first estimate of marine mammal bycatch in the world's fisheries by expanding U.S. bycatch with data on fleet composition from the Food and Agriculture Organization. The global bycatch of marine mammals is in the hundreds of thousands. Bycatch is likely to have significant demographic effects on many populations of marine mammals. Better data are urgently needed to fully understand the impact of these interactions.
Evaluation of reported fatality data associated with workers using respiratory protection in the United States (1990–2012)

ABSTRACT OSHA revised the 1971 respiratory protection standard in 1998 to add guidance for selecting and maintaining respirators. Fatality reports from 1990 to 2012 were used to characterize historical trends in fatalities associated with respirators. Industry- and time-specific trends were evaluated to determine the effect of the revision to the standard on respirator-related fatalities; 174 respirator-related deaths were reported. The majority of fatalities were associated with using an airline respirator (n = 34) or the absence of using a respirator in required spaces (n = 38). Overall, 79% of fatalities were associated with asphyxia. Fatalities were associated with improper employee use or lack of employer compliance. Reductions in fatality rates over time appeared to be associated with the revisions to the respirator standard, although other variables may influence rates (eg, controls). Recommendations for employers and employees regarding maintaining safe use of respirators are provided.
Hepatic Hemangioma in Celiac Patients: Data from a Large Consecutive Series

Background and Aims. Hepatic hemangioma (HH) has a widely ranging prevalence. The etiology is unclear; however, associations with autoimmune disorders have been described. We aimed at evaluating the prevalence of HH in celiac disease. Methods. Ninety-seven consecutive patients with celiac disease (18 M, 79 F, median age 41, and range 17–84 years) underwent liver ultrasound between January 2011 and 2012. The findings were compared with those of 1352 nonceliac patients (581 M, 771 F, median age 50, and range 16–94 years), without liver disease or previously detected HH, who underwent US in the same period. Results. Ultrasonographic findings consistent with HH were observed in 14 celiac patients (14.4%), a prevalence significantly higher than in controls (69 cases, 5.1%) (P = 0.0006). Subgroup analysis showed that, among women, the prevalence of HH was 16.4% in the celiac disease group (13/79) compared with 5.9% in controls (46/771) (P = 0.002). In celiac setting, HH had a median diameter of 1.3 cm and presented as a single lesion in 12 cases (86%). Conclusions. Our findings are consistent with a significantly higher prevalence of HH in celiac patients. Although mechanisms underlying this association remain unclear, autoimmune and metabolic processes, as well as alterations of gut-liver axis equilibrium, could play a role.
The Case of Botulinum Toxin in Milk: Experimental Data

ABSTRACT Botulinum neurotoxin (BoNT) is the most toxic substance known to man and the causative agent of botulism. Due to its high toxicity and the availability of the producing organism Clostridium botulinum, BoNT is regarded as a potential biological warfare agent. Because of the mild pasteurization process, as well as rapid product distribution and consumption, the milk supply chain has long been considered a potential target of a bioterrorist attack. Since, to our knowledge, no empirical data on the inactivation of BoNT in milk during pasteurization are available at this time, we investigated the activities of BoNT type A (BoNT/A) and BoNT/B, as well as their respective complexes, during a laboratory-scale pasteurization process. When we monitored milk alkaline phosphatase activity, which is an industry-accepted parameter of successfully completed pasteurization, our method proved comparable to the industrial process. After heating raw milk spiked with a set amount of BoNT/A or BoNT/B or one of their respective complexes, the structural integrity of the toxin was determined by enzyme-linked immunosorbent assay (ELISA) and its functional activity by mouse bioassay. We demonstrated that standard pasteurization at 72°C for 15 s inactivates at least 99.99% of BoNT/A and BoNT/B and at least 99.5% of their respective complexes. Our results suggest that if BoNTs or their complexes were deliberately released into the milk supply chain, standard pasteurization conditions would reduce their activity much more dramatically than originally anticipated and thus lower the threat level of the widely discussed “BoNT in milk” scenario.
Deep Learning for Classification of Colorectal Polyps on Whole-slide Images

Context: Histopathological characterization of colorectal polyps is critical for determining the risk of colorectal cancer and future rates of surveillance for patients. However, this characterization is a challenging task and suffers from significant inter- and intra-observer variability. Aims: We built an automatic image analysis method that can accurately classify different types of colorectal polyps on whole-slide images to help pathologists with this characterization and diagnosis. Setting and Design: Our method is based on deep-learning techniques, which rely on numerous levels of abstraction for data representation and have shown state-of-the-art results for various image analysis tasks. Subjects and Methods: Our method covers five common types of polyps (i.e., hyperplastic, sessile serrated, traditional serrated, tubular, and tubulovillous/villous) that are included in the US Multisociety Task Force guidelines for colorectal cancer risk assessment and surveillance. We developed multiple deep-learning approaches by leveraging a dataset of 2074 crop images, which were annotated by multiple domain expert pathologists as reference standards. Statistical Analysis: We evaluated our method on an independent test set of 239 whole-slide images and measured standard machine-learning evaluation metrics of accuracy, precision, recall, and F1 score and their 95% confidence intervals. Results: Our evaluation shows that our method with residual network architecture achieves the best performance for classification of colorectal polyps on whole-slide images (overall accuracy: 93.0%, 95% confidence interval: 89.0%–95.9%). Conclusions: Our method can reduce the cognitive burden on pathologists and improve their efficacy in histopathological characterization of colorectal polyps and in subsequent risk assessment and follow-up recommendations.
Structural and Phylogenetic Analyses of the GP42 Transglutaminase from Phytophthora sojae Reveal an Evolutionary Relationship between Oomycetes and Marine Vibrio Bacteria*

Background: The Phytophthora sojae GP42 transglutaminase induces defense responses in parsley and potato. Results: GP42 folds into a novel structure that has arisen through convergent evolution. Conclusion: GP42 has unique structural and enzymatic properties distinct from mammalian or bacterial transglutaminases. Significance: This offers a basis to engineer durable broad spectrum resistance in plants with the design and use of GP42 inhibitors. Transglutaminases (TGases) are ubiquitous enzymes that catalyze selective cross-linking between protein-bound glutamine and lysine residues; the resulting isopeptide bond confers high resistance to proteolysis. Phytophthora sojae, a pathogen of soybean, secretes a Ca2+-dependent TGase (GP42) that is activating defense responses in both host and non-host plants. A GP42 fragment of 13 amino acids, termed Pep-13, was shown to be absolutely indispensable for both TGase and elicitor activity. GP42 does not share significant primary sequence similarity with known TGases from mammals or bacteria. This suggests that GP42 has evolved novel structural and catalytic features to support enzymatic activity. We have solved the crystal structure of the catalytically inactive point mutant GP42 (C290S) at 2.95 Å resolution and identified residues involved in catalysis by mutational analysis. The protein comprises three domains that assemble into an elongated structure. Although GP42 has no structural homolog, its core region displays significant similarity to the catalytic core of the Mac-1 cysteine protease from Group A Streptococcus, a member of the papain-like superfamily of cysteine proteases. Proteins that are taxonomically related to GP42 are only present in plant pathogenic oomycetes belonging to the order of the Peronosporales (e.g. Phytophthora, Hyaloperonospora, and Pythium spp.) and in marine Vibrio bacteria. This suggests that a lateral gene transfer event may have occurred between bacteria and oomycetes. Our results offer a basis to design and use highly specific inhibitors of the GP42-like TGase family that may impair the growth of important oomycete and bacterial pathogens.
Lower Jaw Grip Strength in Healthy and Sick Population Measured by Special Force Transducer

Introduction: One of the basic chronic diseases of the MFH domain that is treated on an outpatient basis is temporomandibular dysfunction (TMD). It represents a number of pathological conditions that lead to the dysfunction of the normal function of the stomatognatic system. Observing the etiologic factors of this condition, temporomandibular TM trauma, poor habits such as infantile type of swallowing, tongue depression, and tectogenic disturbance of the myofunctional squamous system are reported in order to reconstruct the defects of neighboring regions. Material and Methods: The study included 60 patients divided into 3 groups: Group I without predetermined temporomandibular dysfunction, Group II with TMD, and Group III where one of the muscles of the masticatory group was used during the reconstruction procedure. Results: Statistically obtained results show that in group III there is a large difference in postoperative measurement after 6 weeks. Discussion: In the mentioned patients divided into three groups, the measurement of the pressure strength expressed in N follows certain states with it measured values, which coincides with comparative studies. Conclusion: From the obtained results we conclude that the parameter used, the strength of the lower jaw bite is a significant indicator of the chewing system functioning.