Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic detection of epileptic seizure onset and termination using intracranial EEG

This thesis addresses the problem of real-time epileptic seizure detection from intracranial EEG (IEEG). One difficulty in creating an approach that can be used for many patients is the heterogeneity of seizure IEEG patterns across different patients and even within a patient. In addition, simultaneously maximizing sensitivity and minimizing latency and false detection rates has been challenging as these are competing objectives. Automated machine learning systems provide a mechanism for dealing with these hurdles. Here we present and evaluate an algorithm for real-time seizure onset detection from IEEG using a machine-learning approach that permits a patient-specific solution. We extract temporal and spectral features across all intracranial EEG channels. A pattern recognition component is trained using these feature vectors and tested against unseen continuous data from the same patient. When tested on more than 875 hours of IEEG data from 10 patients, the algorithm detected 97% of 67 test seizures of several types with a median detection delay of 5 seconds and a median false alarm rate of 0.6 false alarms per 24-hour period. The sensitivity was 100% for 8 out of 10 patients. These results indicate that a sensitive, specific and relatively short-latency detection system based on machine learning can be employed for seizure detection tailored to individual patients. In addition, we describe and evaluate an algorithm for the detection of the cessation of seizure activity within IEEG. Seizure end detection algorithms can enable important clinical applications such as the delivery of therapy to ameliorate post-ictal symptoms, the detection of status epilepticus, and the estimation of seizure duration. Our machine-learning-based approach is patient-specific. The algorithm is designed to search for the termination of electrographic seizure activity once a seizure has been discovered by a seizure onset detector. When tested on 65 seizures, 88% of all seizure ends were detected within 15 seconds of the time determined by a clinical expert to represent the electrographic end of a seizure. We explore the effects of channel pre-selection on seizure onset detection. We evaluate and present the results from a seizure detector that has been restricted to use only a small subset of the channels available. These channels are manually
Development and Validation of 697 Novel Polymorphic Genomic and EST-SSR Markers in the American Cranberry (Vaccinium macrocarpon Ait.)

The American cranberry, Vaccinium macrocarpon Ait. , is an economically important North American fruit crop that is consumed because of its unique flavor and potential health benefits. However, a lack of abundant, genome-wide molecular markers has limited the adoption of modern molecular assisted selection approaches in cranberry breeding programs. To increase the number of available markers in the species, this study identified, tested, and validated microsatellite markers from existing nuclear and transcriptome sequencing data. In total, new primers were designed, synthesized, and tested for 979 SSR loci; 697 of the markers amplified allele patterns consistent with single locus segregation in a diploid organism and were considered polymorphic. Of the 697 polymorphic loci, 507 were selected for additional genetic diversity and segregation analyses in 29 cranberry genotypes. More than 95% of the 507 loci did not display segregation distortion at the p < 0.05 level, and contained moderate to high levels of polymorphism with a polymorphic information content >0.25. This comprehensive collection of developed and validated microsatellite loci represents a substantial addition to the molecular tools available for geneticists, genomicists, and breeders in cranberry and Vaccinium.
the Effect of Ability to Adjust Self, Work Achievement, and Work Satisfaction

The high quality of employee resources will result in strong commitment in completing routine tasks according to their respective responsibilities and functions more efficiently, effectively and productively. The extent of the authority possessed by the Province in the field of human resource management has resulted in the relevant agencies not carrying out their duties effectively. So that in this study research was conducted for; (1) analyze the ability of employees to adjust to colleagues; (2) analyzing employee work performance; (3) analyzing the level of employee job satisfaction and partial and simultaneous influence. The analytical tool used is Multiple Regression with classical assumption tests. The population in this study were 116 employees of Dispermadesdukcapil, Central Java Province, with a sample of 54 employees. The results of this study that variable adaptability and work performance have a significant positive effect, it is known from the tsatistic value of each of 4.458 and 3.853 which shows a number greater than the ttable number. While the variable job satisfaction has a positive and insignificant effect, it is known from the value of the statistic f-table by 58.548. The suggestions in this study need to be done to improve employees' work, or performance with difficulty behind education. Sumber daya karyawan yang berkualitas tinggi akan menghasilkan komitmen yang kuat dalam menyelesaikan tugas rutin sesuai dengan tanggungjawab dan fungsinya masing-masing secara lebih efisien, efektif dan produktif. Luasnya kewenangan yang dimiliki oleh Provinsi di bidang manajemen sumber daya manusia telah mengakibatkan instansi terkait tidak melaksanakan tugasnya secara efektif. Sehingga dalam penelitian ini dilakukan penelitian untuk; (1) menganalisis kemampuan karyawan untuk menyesuaikan diri dengan rekan kerja; (2) menganalisis kinerja karyawan; (3) menganalisis tingkat kepuasan kerja karyawan dan pengaruh parsial dan simultan. Alat analisis yang digunakan adalah Regresi Berganda dengan tes asumsi klasik. Populasi dalam penelitian ini adalah 116 karyawan Dispermadesdukcapil, Provinsi Jawa Tengah, dengan sampel 54 karyawan. Hasil penelitian ini bahwa variable kemampuan beradaptasi dan kinerja memiliki pengaruh positif yang signifikan, hal ini diketahui dari nilai t satistic masing – masing sebesar 4,458 dan 3,853 yang menunjukkan angka lebih besar dari angkat tabel. Sementara variable kepuasan kerja memiliki efek positif dan tidak signifikan, hal ini diketahui dari nilai statistic f-tabel sebesar 58,548. Saran dalam penelitian ini perlu dilakukan untuk meningkatkan pekerjaan karyawan, atau kinerja dengan kesulitan di belakang pendidikan.
Quality performance in a global supply chain: finding out the weak link

Much has been written on the intensive interconnection between supply chain management (SCM) and quality management (QM) with a particular focus on the systems-based view as the common thread between these two operation management topics. Absent in this debate has been any examination of the dynamics of SCM and QM practices and the resultant implications for the end customer in terms of product/service quality at a global level. In consequence, the nature and extent of their interconnection or interlinking and the resultant implications for the product/service quality has remained tangential. Using a qualitative study of two very large branded athletic and casual sports apparel and footwear manufacturers based in Asia with world-wide suppliers and distribution centres, this study aims to broaden the debate by arguing that partnering with suppliers of high QM capabilities in chains of relationships does not necessarily result in downstream benefits to both the manufacturer and end customers. We argue that both SCM and QM practices must advance from traditional firm-driven, fire fighting and product-focused mindsets to a more collaborative mode of inter-firm relations in that a much greater level of co-operation among both upstream and downstream chains is regarded as a key to competitive advantage.
The impact of oxidation on spore and pollen chemistry

Sporomorphs (pollen and spores) have an outer wall composed of sporopollenin. Sporopollenin chemistry contains both a signature of ambient ultraviolet-B flux and taxonomic information, but it is currently unknown how sensitive this is to standard palynological processing techniques. Oxidation in particular is known to cause physical degradation to sporomorphs, and it is expected that this should have a concordant impact on sporopollenin chemistry. Here, we test this by experimentally oxidizing Lycopodium (clubmoss) spores using two common oxidation techniques: acetolysis and nitric acid. We also carry out acetolysis on eight angiosperm (flowering plant) taxa to test the generality of our results. Using Fourier Transform infrared (FTIR) spectroscopy, we find that acetolysis removes labile, non-fossilizable components of sporomorphs, but has a limited impact upon the chemistry of sporopollenin under normal processing durations. Nitric acid is more aggressive and does break down sporopollenin and reorganize its chemical structure, but when limited to short treatments (i.e. ≤10 min) at room temperature sporomorphs still contain most of the original chemical signal. These findings suggest that when used carefully oxidation does not adversely affect sporopollenin chemistry, and that palaeoclimatic and taxonomic signatures contained within the sporomorph wall are recoverable from standard palynological preparations. Supplementary material: R code for all analyses, the complete dataset and additional figures are available at http://www.geolsoc. org.uk/SUP18811
‘Who would have thought of that!’: A Hierarchical Topic Model for Extraction of Sarcasm-prevalent Topics and Sarcasm Detection

Topic Models have been reported to be beneficial for aspect-based sentiment analysis. This paper reports the first topic model for sarcasm detection, to the best of our knowledge. Designed on the basis of the intuition that sarcastic tweets are likely to have a mixture of words of both sentiments as against tweets with literal sentiment (either positive or negative), our hierarchical topic model discovers sarcasm-prevalent topics and topic-level sentiment. Using a dataset of tweets labeled using hashtags, the model estimates topic-level, and sentiment-level distributions. Our evaluation shows that topics such as ‘work’, ‘gun laws’, ‘weather’ are sarcasm-prevalent topics. Our model is also able to discover the mixture of sentiment-bearing words that exist in a text of a given sentiment-related label. Finally, we apply our model to predict sarcasm in tweets. We outperform two prior work based on statistical classifiers with specific features, by around 25%.
Cardiac Auscultatory Skills of Academic Family Physicians: Strength of Association with an Academic Pediatric Cardiologist

Aim. Heart murmur is common in children, and it is one of the main reasons for referral among children in primary care. The aim of this study is to evaluate agreement and consistency of normal, innocent, and pathologic murmur decision between academic family physicians and academic pediatric cardiologist. Methods. Seven hundred fifteen primary school children were examined by family physicians and paediatric cardiologist. Auscultatory examination was performed. Intensity, frequency, duration, quality, location, and radiation of the murmur were described if present. Agreement of normal, innocent, and pathologic murmur classification decision between family physician and paediatric cardiologist was analyzed by using kappa statistic. Results. Normal, innocent and pathologic murmurs were reported for 419, 228, and 54 children in family physicians' reports, respectively. Paediatric cardiologist agreed on 383 (91.4%) children as normal, 191 (83.7%) children having innocent murmur, and 19 (35.2%) children having pathologic murmur among family physician's reports. There was good consistency between family physicians and paediatric cardiologist (κ value = 0.679, 95% CI 0.630–0.727, P < .001). They agreed on the majority of normal and innocent murmur decisions. However family physicians reported pathologic murmur more frequently. Conclusion. Cardiac auscultatory skills of academic family physicians may be concordant with paediatric cardiologist.
Noninvasive Ventilation with Heliox for Respiratory Distress Syndrome in Preterm Infant: A Systematic Review and Meta-Analysis

Objectives. To assess whether noninvasive ventilation with Heliox reduces the need for endotracheal ventilation and subsequent complications in preterm infants with respiratory distress syndrome (RDS). Methods. A search of major electronic databases, including MEDLINE and the Cochrane Central Register of Controlled Trials, for randomized or quasi-randomized controlled trials that compared noninvasive ventilation with Heliox versus noninvasive ventilation with standard gas for preterm infants with RDS was performed. The primary outcome was the incidence of intubation. The secondary outcomes were the level of PaCO2, the use of surfactant, and other complications. Results. Two randomized and one quasi-randomized controlled trials including 123 preterm infants were assessed. Heliox was found to significantly decrease the incidence of intubation (RR: 0.42; 95% CI: 0.23 to 0.78), the level of PaCO2 (MD: −9.61; 95% CI: −15.76 to −03.45), and the use of surfactant (RR: 0.25; 95% CI: 0.10 to 0.61) as compared with standard gas. No significant differences were found in other secondary outcomes. Conclusions. Noninvasive ventilation with Heliox decreases the incidence of intubation in preterm infants suffering from RDS. However, data on clinical outcomes are limited. Larger trials are needed to verify the beneficial effects.
Psychophysical exploration of stereoscopic pseudo-transparency

We report an experiment related to perceiving (virtual) objects in the vicinity of (real) surfaces when using stereoscopic augmented reality displays. In particular, our goal was to explore the effect of various visual surface features on both perception of object location and perception of surface transparency. Surface features were manipulated using random dot patterns on a simulated real object surface, by manipulating dot size, dot density, and whether or not objects placed behind the surface were partially occluded by the surface.
Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon

Specification of the forebrain, midbrain and hindbrain primordia occurs during gastrulation in response to signals that pattern the gastrula embryo. Following establishment of the primordia, each brain part is thought to develop largely independently from the others under the influence of local organizing centers like the midbrain-hindbrain boundary (MHB, or isthmic) organizer. Mechanisms that maintain the integrity of brain subdivisions at later stages are not yet known. To examine such mechanisms in the anterior neural tube, we have studied the establishment and maintenance of the diencephalic-mesencephalic boundary (DMB). We show that maintenance of the DMB requires both the presence of a specified midbrain and a functional MHB organizer. Expression of pax6.1, a key regulator of forebrain development, is posteriorly suppressed by the Engrailed proteins, Eng2 and Eng3. Mis-expression of eng3 in the forebrain primordium causes downregulation of pax6.1, and forebrain cells correspondingly change their fate and acquire midbrain identity. Conversely, in embryos lacking both eng2 and eng3, the DMB shifts caudally into the midbrain territory. However, a patch of midbrain tissue remains between the forebrain and the hindbrain primordia in such embryos. This suggests that an additional factor maintains midbrain cell fate. We find that Fgf8 is a candidate for this signal, as it is both necessary and sufficient to repress pax6.1 and hence to shift the DMB anteriorly independently of the expression status of eng2/eng3. By examining small cell clones that are unable to receive an Fgf signal, we show that cells in the presumptive midbrain neural plate require an Fgf signal to keep them from following a forebrain fate. Combined loss of both Eng2/Eng3 and Fgf8 leads to complete loss of midbrain identity, resulting in fusion of the forebrain and the hindbrain primordia. Thus, Eng2/Eng3 and Fgf8 are necessary to maintain midbrain identity in the neural plate and thereby position the DMB. This provides an example of a mechanism needed to maintain the subdivision of the anterior neural plate into forebrain and midbrain.
A space-time variational formulation for the boundary integral equation in a 2D elastic crack problem

— This paper investigates the transient elastic wave scattering by a crack in R by means of Boundary Integral Equation Method. The analysis of the Laplace-Fourier transform (in time) of the integral operator allows to obtain existence, uniqueness and continuity dependence of the solution with respect to the data, in a Sobolev functional framework. A regularisation of the hypersingular BIE is applied in order to remove the hypersingularity and to write the associated time-space variational formulation on a tractable form. A Galerkin-type approximation is then performed to solve this variational formulation and we finally present some numerical results. Resume. — Nous nous interessons a la resolution par une methode d'equations integrales d'un probleme de diffraction d'ondes elastiques transitoires par une fissure. L'analyse de la transformee de F ourier-Laplace (en temps) de Voperateur integral permet d'obtenir des resultats d'existence, d'unicite et de continuite de la solution par rapport aux donnees dans des espaces fonctionnels de type Sobolev. Le noyau de V equation integrale etant hypersingulier, on ne dispose pas directement d'une expression calculable de la forme bilineaire associee. Cette difficulte est surmontee en appliquant une methode de regularisation qui fournit finalement la formulation variationnelle espace-temps du probleme. Cette formulation est enfin approchee a l'aide d'un schema de Galerkin et nous presentons quelques resultats numeriques.
Australian university student finances 2006 : final report of a national survey of students in public universities

This work is copyright-free to universities and other relevant bodies provided that attribution of authorship is made to Universities Australia. Apart from such use, all rights in copyright are reserved. Australian University Student Finances 2006 ii Tables Table 2.1 Number of non-Indigenous undergraduate and postgraduate respondents, Australian University Student Finances 2006 iii Table 6.8 Part-time students who would prefer to study full-time if finances permitted,
Disabled 'R' all: bridging the gap between health and situational induced impairments and disabilities

More and more people interact with mobile devices whilst walking. This new interaction paradigm imposes a novel set of challenges and restrictions to mobile users, denominated Situationally-Induced Impairments and Disabilities. The tremor originated of such contexts results in inaccurate movements and erroneous actions. These difficulties are particularly visible in recent touch interfaces that lack the tactile cues and physical stability provided by their keypad-based counterparts. Nevertheless, these difficulties are not new to the accessibility community, particularly for those studying motor impaired users. In fact, both user populations (situationally and physically impaired) seem to share similar interaction problems. This work aims to thoroughly understand to what extend technology can be transferred between those domains. Unlike the embryonic stage of mobile research, the accessibility community has the accumulated knowledge of more than two decades of research. Building a relationship between these domains will contribute towards a more inclusive and universal design approach, which will benefit and bring closer two distinct research communities.
Iterated Belief Revision: A Computational Approach

The capability of revising its beliefs upon new information in a rational and ecien t way is crucial for an intelligent agent. The classic AGM theory studies mathematically idealized models of belief revision in two aspects: the properties (i.e., the AGM postulates) a rational re- vision operator should satisfy; and how to construct concrete revision operators. In scenarios where new information arrives in sequence, ratio- nal revision operators should also respect postulates for iterated revision (e.g., the DP postulates). When applications are concerned, the idealiza- tion of the AGM theory has to be lifted, in particular, beliefs of an agent should be represented by a nite belief base. In this paper, we present a computational base revision operator, which satises the AGM pos- tulates and postulates for iterated revision. We will show that our base revision operator is almost optimal in terms of computational complex- ity. Furthermore, the base revision operator's degrees of syntax relevance and minimal change are also formally analyzed.
Correlation between spectral measures of systolic blood pressure variability and heart rate variability during paced breathing, standing and exercise

To provide insight on the somewhat controversial issue of the physiological correlates of spectral indexes of systolic pressure variability (SPV) we assessed the relations between them and those of heart rate variability (HRV) in 20 subjects during two sympathetic maneuvers, standing (S) and exercise (E). We also evaluated the percentage of statistical differences among 50-s epochs (PSDE) of the spectral measures dynamics obtained in 5-min steady-state conditions. From time-frequency spectra, high-frequency power of RR intervals (HF<sub>RR</sub>), low-to-high-frequency ratio (LF<sub>RR</sub>/HF<sub>RR</sub>), low-frequency of systolic pressure (LF<sub>SP</sub>), high-frequency of systolic pressure (HF<sub>SP</sub>), high-frequency of respiration (HF<sub>Re</sub>) and HF<sub>SP</sub>-HF<sub>Re</sub> time-frequency coherence were computed. LF<sub>SP</sub>-lnHF<sub>RR</sub>, LF<sub>SP</sub>-RR and LF<sub>SP</sub>-LF<sub>RR</sub>/HF<sub>RR</sub> correlations were -0.73±0.09, -0.77±0.06, and 0.66±0.13 respectively. During E, HF<sub>RR</sub> decreased, HF<sub>SP</sub> increased (p<;0.001) and HF<sub>Re</sub>-HF<sub>SP</sub> coherence was 0.93±0.05. Global PSDE of the measures was 41±18%. HRV spectral measures show strong correlation with LF<sub>SP</sub> power, novel evidence that supports its suitability as sympathetic index. The differential effect of E on HF<sub>RR</sub> and HF<sub>SP</sub> and high HF<sub>SP</sub>-HF<sub>Re</sub> coherence document the mechanical respiratory origin of HF<sub>SP</sub>. Spectral measures of supposedly steady-state maneuvers present high PSDE.