Miracle-dz/UniFAR-FTUs huggingface dataset:
Ultra-wideband silicon on-chip antennas with artificial dielectric layer

On-chip antennas are demanded to further lower the cost of wireless CMOS ICs. We placed an artificial dielectric layer (ADL) between an antenna and Si substrate to improve the antenna gain. A 3.1-10.6-GHz ultra-wideband inverted-F antenna with ADL as well as a low-noise amplifier were designed and fabricated using a 0.18-µm mixed signal/RF CMOS process with one poly and six metal layers. A fairly good agreement between measured and calculated gain characteristics was obtained. Using the ADL achieved a 2-dB gain enhancement. Increasing the surface dielectric constant for the ADL is expected to further enhance gain.
Changes in Physical Fitness, Bone Mineral Density and Body Composition During Inpatient Treatment of Underweight and Normal Weight Females with Longstanding Eating Disorders

The purpose of this study was to examine changes in aerobic fitness, muscular strength, bone mineral density (BMD) and body composition during inpatient treatment of underweight and normal weight patients with longstanding eating disorders (ED). Twenty-nine underweight (BMI < 18.5, n = 7) and normal weight (BMI ≥ 18.5, n = 22) inpatients (mean (SD) age: 31.0 (9.0) years, ED duration: 14.9 (8.8) years, duration of treatment: 16.6 (5.5) weeks) completed this prospective naturalistic study. The treatment consisted of nutritional counseling, and 2 × 60 min weekly moderate intensive physical activity in addition to psychotherapy and milieu therapy. Underweight patients aimed to increase body weight with 0.5 kg/week until the weight gain goal was reached. Aerobic fitness, muscular strength, BMD and body composition were measured at admission and discharge. Results showed an increase in mean muscular strength, total body mass, fat mass, and body fat percentage, but not aerobic capacity, among both underweight and normal weight patients. Lumbar spine BMD increased among the underweight patients, no changes were observed in BMD among the normal weight patients. Three out of seven underweight patients were still underweight at discharge, and only three out of nine patients with excessive body fat (i.e., >33%) managed to reduce body fat to normal values during treatment. These results calls for a more individualized treatment approach to achieve a more optimal body composition among both underweight and normal to overweight patients with longstanding ED.
Evidence for Acquisition in Nature of a Chromosomal 2,4-Dichlorophenoxyacetic Acid/(alpha)-Ketoglutarate Dioxygenase Gene by Different Burkholderia spp

We characterized the gene required to initiate the degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) by the soil bacterium Burkholderia sp. strain TFD6, which hybridized to the tfdA gene of the canonical 2,4-D catabolic plasmid pJP4 under low-stringency conditions. Cleavage of the ether bond of 2,4-D by cell extracts of TFD6 proceeded by an (alpha)-ketoglutarate-dependent reaction, characteristic of TfdA (F. Fukumori and R. P. Hausinger, J. Bacteriol. 175:2083-2086, 1993). The TFD6 tfdA gene was identified in a recombinant plasmid which complemented a tfdA transposon mutant of TFD6 created by chromosomal insertion of Tn5. The plasmid also expressed TfdA activity in Escherichia coli DH5(alpha), as evidenced by enzyme assays with cell extracts. Sequence analysis of the tfdA gene and flanking regions from strain TFD6 showed 99.5% similarity to a tfdA gene cloned from the chromosome of a different Burkholderia species (strain RASC) isolated from a widely separated geographical area. This chromosomal gene has 77.2% sequence identity to tfdA from plasmid pJP4 (Y. Suwa, W. E. Holben, and L. J. Forney, abstr. Q-403, in Abstracts of the 94th General Meeting of the American Society for Microbiology 1994.). The tfdA homologs cloned from strains TFD6 and RASC are the first chromosomally encoded 2,4-D catabolic genes to be reported. The occurrence of highly similar tfdA genes in different bacterial species suggests that this chromosomal gene can be horizontally transferred.
Caffe: Convolutional Architecture for Fast Feature Embedding

Caffe provides multimedia scientists and practitioners with a clean and modifiable framework for state-of-the-art deep learning algorithms and a collection of reference models. The framework is a BSD-licensed C++ library with Python and MATLAB bindings for training and deploying general-purpose convolutional neural networks and other deep models efficiently on commodity architectures. Caffe fits industry and internet-scale media needs by CUDA GPU computation, processing over 40 million images a day on a single K40 or Titan GPU (approx 2 ms per image). By separating model representation from actual implementation, Caffe allows experimentation and seamless switching among platforms for ease of development and deployment from prototyping machines to cloud environments. Caffe is maintained and developed by the Berkeley Vision and Learning Center (BVLC) with the help of an active community of contributors on GitHub. It powers ongoing research projects, large-scale industrial applications, and startup prototypes in vision, speech, and multimedia.
Reduction in Heart Rate Variability with Traffic and Air Pollution in Patients with Coronary Artery Disease

Introduction Ambient particulate pollution and traffic have been linked to myocardial infarction and cardiac death risk. Possible mechanisms include autonomic cardiac dysfunction. Methods In a repeated-measures study of 46 patients 43–75 years of age, we investigated associations of central-site ambient particulate pollution, including black carbon (BC) (a marker for regional and local traffic), and report of traffic exposure with changes in half-hourly averaged heart rate variability (HRV), a marker of autonomic function measured by 24-hr Holter electrocardiogram monitoring. Each patient was observed up to four times within 1 year after a percutaneous intervention for myocardial infarction, acute coronary syndrome without infarction, or stable coronary artery disease (4,955 half-hour observations). For each half-hour period, diary data defined whether the patient was home or not home, or in traffic. Results A decrease in high frequency (HF; an HRV marker of vagal tone) of −16.4% [95% confidence interval (CI), −20.7 to −11.8%] was associated with an interquartile range of 0.3-μg/m3 increase in prior 5-day averaged ambient BC. Decreases in HF were independently associated both with the previous 2-hr averaged BC (−10.4%; 95% CI, −15.4 to −5.2%) and with being in traffic in the previous 2 hr (−38.5%; 95% CI, −57.4 to −11.1%). We also observed independent responses for particulate air matter with aerodynamic diameter ≤ 2.5 μm and for gases (ozone or nitrogen dioxide). Conclusion After hospitalization for coronary artery disease, both particulate pollution and being in traffic, a marker of stress and pollution, were associated with decreased HRV.
Texture Analysis with MTEX – Free and Open Source Software Toolbox

The MATLAB™ toolbox MTEX provides a unique way to represent, analyse and interpret crystallographic preferred orientation, i.e. texture, based on integral (“pole figure”) or individual orientation (“EBSD”) measurements. In particular, MTEX comprises functions to import, analyse and visualize diffraction pole figure data as well as EBSD data, to estimate an orientation density function from either kind of data, to compute texture characteristics, to model orientation density functions in terms of model functions or Fourier coefficients, to simulate pole figure or EBSD data, to create publication ready plots, to write scripts for multiple use, and others. Thus MTEX is a versatile free and open-source software toolbox for texture analysis and modeling.
A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

Sirtuins are protein deacetylases regulating metabolism, stress responses, and aging processes, and they were suggested to mediate the lifespan extending effect of a low calorie diet. Sirtuin activation by the polyphenol resveratrol can mimic such lifespan extending effects and alleviate metabolic diseases. The mechanism of Sirtuin stimulation is unknown, hindering the development of improved activators. Here we show that resveratrol inhibits human Sirt3 and stimulates Sirt5, in addition to Sirt1, against fluorophore-labeled peptide substrates but also against peptides and proteins lacking the non-physiological fluorophore modification. We further present crystal structures of Sirt3 and Sirt5 in complex with fluorogenic substrate peptide and modulator. The compound acts as a top cover, closing the Sirtuin’s polypeptide binding pocket and influencing details of peptide binding by directly interacting with this substrate. Our results provide a mechanism for the direct activation of Sirtuins by small molecules and suggest that activators have to be tailored to a specific Sirtuin/substrate pair.
An appraisal of golimumab in the treatment of severe, active nonradiographic axial spondyloarthritis

Golimumab (Simponi®) is a fully human tumor necrosis factor α inhibitor (TNFi) antibody administered subcutaneously. In the European Union, golimumab is indicated for the treatment of adults with severe, active axial spondyloarthritis (axSpA), which includes both ankylosing spondylitis (AS) and nonradiographic axSpA (nr-axSpA). In the US, it is indicated for the treatment of adults with active AS only. This article reviews the efficacy and tolerability of golimumab in nr-axSpA patients compared to other TNFi agents (adalimumab, infliximab, etanercept, and certolizumab pegol). In one ongoing, well-designed controlled study (GO-AHEAD), data at 16 weeks showed that treatment with golimumab (50 mg every 4 weeks) was effective in improving the clinical signs and symptoms of disease in nr-axSpA patients. In addition, 16 weeks of treatment with golimumab reduced inflammation in the sacroiliac joints and spine in patients with nr-axSpA. Moreover, objective evidence of active inflammation at baseline, such as a positive magnetic resonance imaging scan and/or an elevated CRP level, was a good predictor of treatment response to golimumab. Golimumab was generally well tolerated in this study, with a tolerability profile consistent with that seen in previous clinical trials for other indications. Although additional long-term data are needed, current evidence indicates that golimumab is an effective option for the treatment of nr-axSpA. However, in the absence of comparative head-to-head trials, there is no recommended hierarchy for the first prescription of a TNFi agent for the treatment of either nr-axSpA or AS.
Unbiased maximum SINR prefiltering for reduced-state equalization

We consider prefiltering for a single-carrier transmission over frequency-selective channels, where reduced-state trellis-based equalization is employed at the receiver. While previously proposed prefiltering schemes are based on the optimum filters of decision-feedback equalization (DFE), the prefiltering scheme introduced in this paper is designed according to a signal-to-interference-plus-noise ratio (SINR), whose definition takes into account explicitly the subsequent trellis-based equalizer and its complexity. In addition to the prefilter, a finite-length target impulse response for trellis-based equalization and a feedback filter for state-dependent decision feedback in equalization, respectively, is determined. However, it is shown that a direct maximization of the SINR with respect to all filters results in a biased solution, and the relation of this solution to an optimum unbiased solution with improved error rate performance, which is also derived, is investigated.
Combining Logical Abduction and Statistical Induction: Discovering Written Primitives with Human Knowledge

In many real tasks there are human knowledge expressed in logic formulae as well as data samples described by raw features (e.g., pixels, strings). It is popular to apply SRL or PILPtechniques to exploit human knowledge through learning of symbolic data, or statistical learning techniques to learn from the raw data samples; however, it is often desired to directly exploit these logic formulae on raw data processing, like human beings utilizing knowledge to guide perception. In this paper, we propose an approach, LASIN, which combines Logical Abduction and Statistical Induction. The LASIN approach generates candidate hypotheses based on the abduction of first-order formulae, and then, the hypotheses are exploited as constraints for statistical induction. We apply theLASIN approach to the learning of representation of written primitives, where a primitive is a basic component in human writing. Our results show that the discovered primitives are reasonable for human perception, and these primitives, if used in learning tasks such as classification and domain adaptation, lead to better performances than simply applying feature learning based on raw data only.
Usage-based pricing law to charge IP network services with performance guarantees

In the present day Internet, the provision of different levels of performance guarantees, appropriate for the type of supported applications and the willingness of users to pay, is a pressing need. Since flat-rate fees are probably inadequate to charge differentiated services, the need to provide usage-based tariff models to charge IP guaranteed services, and therefore to develop business interactions, is expected. We define the network service commodity, traded in a future Internet scenario, as the transfer of information units between two points of the network, and we present an approach to measure it as a function of so called virtual delay. In our approach, the virtual delay summarizes the parameters characterizing the performance guarantees of the transfer service. Under these assumptions, we propose a pricing law to charge improved IP services depending on the duration of the connection and on the traffic volume exchanged during the communication. The tariff is a function of the actually used and/or reserved network resources, so as to satisfy the requirements of users and network management, respectively.
Inputs from identified jaw‐muscle spindle afferents to trigeminothalamic neurons in the rat: A double‐labeling study using retrograde HRP and intracellular biotinamide

Projections from physiologically identified jaw‐muscle spindle afferents onto trigeminothalamic neurons were studied in the rat. Trigeminothalamic neurons were identified by means of retrograde transport of horseradish peroxidase from the ventroposteromedial nucleus of the thalamus. Labeled neurons were found contralaterally in the supratrigeminal region (Vsup), the trigeminal principal sensory nucleus, the ventrolateral part of the trigeminal subnucleus oralis, the spinal trigeminal subnuclei interpolaris and caudalis, the reticular formation, and an area ventral to the trigeminal motor nucleus (Vmo) and medial to the trigeminal principal sensory nucleus (AVM). Jaw‐muscle spindle afferents were physiologically identified by their increased firing during stretehing of the jaw muscles and intracellularly injected with biotinamide. Axon collaterals and boutons from jaw‐muscle spindle afferents were found in Vmo; Vsup; the dorsomedial part of the trigeminal principal sensory nucleus (Vpdm); the dorsomedial part of the spinal trigeminal subnuclei oralis, interpolaris (Vidm) and caudalis; the parvicellular reticular formation (PCRt); and the mesencephalic trigeminal nucleus. Trigeminothalamic neurons in Vsup, Vpdm, Vidm, PCRt, and AVM were associated with axon collaterals and boutons from intracellularly stained jaw‐muscle spindle afferents. Trigeminothalamic neurons in Vsup, Vpdm, Vidm, and PCRt were closely apposed by one to 14 intracellularly labeled boutons from jaw‐muscle spindle afferents, suggesting a powerful input to some trigeminothalamic neurons. These data demonstrate that muscle length and velocity feedback from jaw‐muscle spindle afferents is projected to the contralateral thalamus via multiple regions of the trigeminal system and implicates these pathways in the projection of trigeminal proprioceptive information to the cerebral cortex. © 1995 Wiley‐Liss, Inc.
Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa-associated lymphoid tissue lymphoma.

BACKGROUND Low-grade B-cell lymphomas arising in mucosa-associated lymphoid tissue (MALT) are most frequently localized in the gastrointestinal tract. More than 90% of gastric MALT lymphomas are diagnosed in patients with chronic, Helicobacter pylori-associated gastritis. High remission rates for these lymphomas have been observed after the cure of H. pylori infection. Data are lacking, however, with regard to the duration of the remissions. To address this question of remission duration, we have followed 50 patients in whom H. pylori infections were eradicated, and we determined whether the patients in complete remission displayed evidence of residual monoclonal B cells during follow-up. METHODS Patients were treated with amoxycillin and omeprazole for 2 weeks in an attempt to cure H. pylori infections. Follow-up included endoscopic investigations with biopsy sampling. Monoclonal B cells in biopsy specimens were detected by means of a polymerase chain reaction (PCR)-based assay. RESULTS H. pylori infections were cured in all 50 patients. The median follow-up for the 50 patients is currently 24 months (729 days; range, 135-1411 days). Forty patients achieved complete remission of their lymphomas, but five have subsequently relapsed. The median time of continuous complete remission for the 40 patients was 15.4 months (468 days; range, 0-1198 days). Among six patients whose Iymphomas did not respond to H. pylori eradication, four revealed high-grade lymphomas upon surgery. PCR indicated the presence of monoclonal B cells during follow-up in 22 of 31 assessable patients in complete remission. CONCLUSIONS Complete remissions of low-grade gastric MALT Iymphomas after the cure of H. pylori infection appear to be stable, although most patients display evidence of monoclonal B cells during follow-up. Whether these patients are truly cured of their Iymphomas remains to be determined.
How training and testing histories affect generalization: a test of simple neural networks

We show that a simple network model of associative learning can reproduce three findings that arise from particular training and testing procedures in generalization experiments: the effect of (i) ‘errorless learning’, (ii) extinction testing on peak shift, and (iii) the central tendency effect. These findings provide a true test of the network model which was developed to account for other phenomena, and highlight the potential of neural networks to study the phenomena that depend on sequences of experiences with many stimuli. Our results suggest that at least some such phenomena, e.g. stimulus range effects, may derive from basic mechanisms of associative memory rather than from more complex memory processes.
Evaluation of a Chromogenic Agar for Detection of Group B Streptococcus in Pregnant Women

ABSTRACT We compared ChromID Strepto B agar (STRB; bioMérieux, Inc.), a selective and differential medium for group B streptococcus, with culture using neomycin-nalidixic acid agar (NNA) and LIM broth. STRB alone was more sensitive (87.7%) than NNA alone (79.0%), while each had a sensitivity of 100% when used in conjunction with LIM broth.
Projective Geometries Over Finite Fields

1. Finite fields 2. Projective spaces and algebraic varieties 3. Subspaces 4. Partitions 5. Canonical forms for varieties and polarities 6. The line 7. First properties of the plane 8. Ovals 9. Arithmetic of arcs of degree two 10. Arcs in ovals 11. Cubic curves 12. Arcs of higher degree 13. Blocking sets 14. Small planes Appendix Notation References
Real-time multiplexing of mixed-criticality data streams for Automotive Multi-Core Test Systems

Historically, automotive test systems were designed for a single core architecture. This, however, limited the utilization of shared resources. In this paper we present a redesign of an automotive test system that is based on a multi-core architecture and capable of managing mixed-criticality data. As part of the redesign, we implemented a Connectivity Manager (CM) that is in charge of multiplexing several data streams from multiple cores across a shared network. Due to the increased complexity of our system, a more flexible scheduling approach is required. Our solution to this problem is a novel dynamic priority communication scheduling approach that adapts to bandwidth changes on the shared communication network. Through simulations with realistic workloads, we prove the proper functioning of our algorithm with the result that higher critical data streams are favoured over less critical data streams in case of an overloaded system caused by a bottleneck on the CAN bus.
25-Hydroxyvitamin D in Obese Youth Across theSpectrumofGlucoseTolerance FromNormal to Prediabetes to Type 2 Diabetes

RESEARCH DESIGN AND METHODSdPlasma 25(OH)D concentrations were examined in banked specimens in 9to 20-year-old obese youth (n = 175; male 42.3%, black 46.3%) (NGT, n = 105; impaired glucose tolerance [IGT], n = 43; type 2 diabetes, n = 27) who had in vivo insulin sensitivity and secretion measured by hyperinsulinemic-euglycemic and hyperglycemic clamp techniques and had an assessment of total body composition and abdominal adiposity.
Functionally and anatomically segregated visual pathways in the lobula complex of a calliphorid fly

In dipteran insects, the lobula plate neuropil provides a major efferent supply to the premotor descending neurons that control stabilized flight. The lobula plate itself is supplied by two major parallel retinotopic pathways from the medulla: small‐field, magnocellular afferents that are implicated in achromatic motion processing and Y cells that connect the medulla with both the lobula plate and the lobula. A third pathway from the medulla involves transmedullary (Tm) neurons, which provide inputs to palisades of small‐field neurons in the lobula. Although, in their passage to the brain, many output neurons from the lobula plate are separated physically from their counterparts in the lobula, there is an additional class of lobula complex output neurons. This group is composed of retinotopic lobula plate‐lobula (LPL) and lobula‐lobula plate (LLP) cells, each of which has dendrites in both the lobula and the lobula plate. The present account describes the anatomy and physiology of exemplars of LPL and LLP neurons, a wide‐field tangential neuron that is intrinsic to the lobula complex, and representatives of the Tm‐ and Y‐cell pathways. We demonstrate novel features of the lobula plate, which previously has been known as a motion‐collating neuropil, and now also can be recognized as supporting direction‐ or nondirection‐specific responses to local motion, encoding of contrast frequency, and processing of local structural features of the visual panorama. J. Comp. Neurol. 396:84–104, 1998. © 1998 Wiley‐Liss, Inc.