Miracle-dz/UniFAR-FTUs huggingface dataset:
The Childhood Factor

This article explores the significance of childhood experience of woodlands and other green or natural places in relation to adult patterns of use and attitudes to such places. It draws on data collected in different parts of Britain. Questionnaires were used to explore the frequency of adults' visits to green places, the frequency with which they reported visiting such places as children, and their attitudes to different attributes of the places they visited. The data show a strong relationship between frequent childhood visits and being prepared to visit woodlands or green spaces alone as an adult. By contrast, not visiting as a child was associated with a very low likelihood of later adult visits. The data also suggest that the physical and the emotional benefits of access to green space are strongly reflected in childhood experience. The significance of these findings for today's children, as they become adults, is discussed.
Abusive supervision and workplace deviance: the mediating role of interactional justice and the moderating role of power distance

This study replicates previous studies by examining the effects of abusive supervision on employee deviant behaviours in the Chinese organisational context. It extends the existing research of abusive supervision by investigating the mediating role of the perception of interactional justice and the moderating role of individual-level power distance in the link between abusive supervision and workplace deviance. Regression analyses on data of 283 employee–supervisor dyads revealed that the perception of interactional justice mediates the link between abusive supervision and workplace deviance. We also found that abusive supervision has a stronger negative relationship with the perception of interactional justice for employees low in power distance than for employees high in power distance. These findings provide both replications of and extensions to western theories of abusive supervision and workplace deviance. Practical implications of this study include hints for reducing both financial and psychological costs of deviant behaviour.
Efficient parallelization of a regional ocean model for the western Mediterranean Sea

This paper focuses on the parallelization of an ocean model applying current multicore processor-based cluster architectures to an irregular computational mesh. The aim is to maximize the efficiency of the computational resources used. To make the best use of the resources offered by these architectures, this parallelization has been addressed at all the hardware levels of modern supercomputers: firstly, exploiting the internal parallelism of the CPU through vectorization; secondly, taking advantage of the multiple cores of each node using OpenMP; and finally, using the cluster nodes to distribute the computational mesh, using MPI for communication within the nodes. The speedup obtained with each parallelization technique as well as the combined overall speedup have been measured for the western Mediterranean Sea for different cluster configurations, achieving a speedup factor of 73.3 using 256 processors. The results also show the efficiency achieved in the different cluster nodes and the advantages obtained by combining OpenMP and MPI versus using only OpenMP or MPI. Finally, the scalability of the model has been analysed by examining computation and communication times as well as the communication and synchronization overhead due to parallelization.
Cooperative and Competitive Behavior

The cooperative-competitive behavior of children in Papua New Guinea was assessed by two experimental techniques that have previously been used within other countries to demonstrate ethnic differences. The results of Experiments 1 and 2, in which the Madsen cooperation board was used, indicate significantly more cooperation between children of an intact tribe than between children in a heterogeneous urban setting. In Experiment 3, the marble-pull apparatus was used to assess the cooperative interaction of children from ten sites which varied in tribal intactness, degree of western contact, and urbanization. The results demonstrate the significance of primary group identification as a determinant of cooperative behavior.
Private Girls and Public Worlds: Producing femininities in the primary school

This article draws upon data gathered from a research project entitled 'Children's Relationship Cultures in Years 5 and 6'. The project aims to explore the ways in which primary school age children understand emotional, caring and family relationships. This paper will focus upon the role of friendship in the cultures of girls, aged 9-10, in a primary school classroom. An ethnographic approach is adopted to illustrate the variety of interactions in which friendship is spoken, displayed and enacted within pupil cultures. Analysis of these exchanges suggests that notions of friendship and patterns of friendship are constitutive of sexual-gender identities. The paper argues that being friends/breaking friends is a technique utilised for the regulation and negotiation of femininities and the production of differentiated sex-gender hierarchies. The paper will focus upon the activities of the 'diary group'--a self-styled network of eight girls who met in the school playground to discuss issues that interested and excited them. Recurrent themes in diary group discussions are identified as: puberty/periods; erotic attachments; and imagined futures. The paper suggests that the diary group can be seen as a site for identity production and asks the question: what kind of identities are being produced when these girls meet and talk? Finally, the paper seeks to explore the ways in which members of the diary group create a 'private' space within the public domain of the school and, through talk, produce themselves as feminine subjects.
Thienorphine: Receptor Binding and Behavioral Effects in Rhesus Monkeys

Thienorphine is an oripavine with long-lasting antinociceptive effects in mice that are thought to be mediated by μ-opioid receptors. This study examined the receptor binding of thienorphine in cell membrane homogenates and its behavioral effects in rhesus monkeys (Macaca mulatta). Affinity and potency were determined using radioligand displacement and stimulation of guanosine 5′-O-(3-[35S]thio)triphosphate binding in C6 (μ, δ) and Chinese hamster ovary (κ) cell membranes. Thienorphine displayed high affinity for κ-, μ-, and δ-opioid receptors with Ki values of 0.14, 0.22, and 0.69 nM, respectively. Thienorphine partially stimulated κ-opioid (75%) and μ-opioid (19%) receptors and not δ-opioid receptors. Thienorphine dose-dependently increased tail-withdrawal latency for 50°C water and not 55°C water with effects lasting for more than 7 days. The κ-opioid receptor antagonist nor-binaltorphimine (nor-BNI) (3.2 mg/kg) and a large dose (1.0 mg/kg) of naltrexone prevented thienorphine-induced antinociception. Thienorphine enhanced the antinociceptive effects of morphine and U50,488 [trans-3, 4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamide] with 50°C water; with 55°C water, thienorphine enhanced the effects of morphine and attenuated the effects of U50,488. In other monkeys, thienorphine decreased responding in both components of a multiple schedule of food presentation and stimulus shock termination for up to 8 days; naltrexone and nor-BNI partially prevented these rate-decreasing effects. In morphine-treated monkeys discriminating naltrexone, thienorphine, and U50,488 neither substituted for nor modified the naltrexone discriminative stimulus. Thienorphine and U50,488 produced the same directly observable signs. These results show that thienorphine has long-lasting effects that seem to be mediated by low-efficacy agonism at κ-opioid receptors, both in vitro and in vivo.
cAMP and EPAC Are Key Players in the Regulation of the Signal Transduction Pathway Involved in the α-Hemolysin Autophagic Response

Staphylococcus aureus is a microorganism that causes serious diseases in the human being. This microorganism is able to escape the phagolysosomal pathway, increasing intracellular bacterial survival and killing the eukaryotic host cell to spread the infection. One of the key features of S. aureus infection is the production of a series of virulence factors, including secreted enzymes and toxins. We have shown that the pore-forming toxin α-hemolysin (Hla) is the S. aureus–secreted factor responsible for the activation of the autophagic pathway and that this response occurs through a PI3K/Beclin1-independent form. In the present report we demonstrate that cAMP has a key role in the regulation of this autophagic response. Our results indicate that cAMP is able to inhibit the autophagy induced by Hla and that PKA, the classical cAMP effector, does not participate in this regulation. We present evidence that EPAC and Rap2b, through calpain activation, are the proteins involved in the regulation of Hla-induced autophagy. Similar results were obtained in cells infected with different S. aureus strains. Interestingly, in this report we show, for the first time to our knowledge, that both EPAC and Rap2b are recruited to the S. aureus–containing phagosome. We believe that our findings have important implications in understanding innate immune processes involved in intracellular pathogen invasion of the host cell.
Identification and Assessment of Children with Dyslexia in Allahabad City

The survey method was adopted for the present study. The investigation was conducted in different schools of Allahabad district including five English medium schools and five Hindi medium schools with respect to the identification and assessment of children with reading related problems (dyslexia). The sample comprised of the teachers teaching English language to identify the children having reading related problems (dyslexia) from 2 nd to 8 th
The Effects of the Primary Movement Programme on the Academic Performance of Children Attending Ordinary Primary School.

The present study investigated the prevalence of a primary reflex (the Asymmetrical Tonic Neck Reflex) in children attending ordinary primary school and how this related to attainments in a number of academic areas. The effectiveness of a specific movement intervention programme in reducing primary reflex persistence and improving academic attainment was also evaluated. A comparative study of the progress of 683 children over a two-year period from Years 3 and 5, who completed an intervention programme known as Primary Movement, was carried out using the relative attainments of children at the same schools and standardised scores as baseline and follow-up measures. A second, quasi-experimental study followed the progress of four parallel groups in each of two large schools with the experimental side completing the movement intervention programme while the other side acted as the control. It was found that ATNR persistence was significantly associated with level of attainments in reading, spelling and mathematics and that boys were more at risk than girls for ATNR persistence. In both studies, it was found that the movement intervention programme had a very significant impact on reducing the levels of ATNR persistence in children and that this was associated with very significant improvements in reading and mathematics, in particular. This research provides further evidence of a link between the attainment of core educational skills and the interference that may result from an underlying developmental deficit. The effectiveness of the intervention programme in reducing ATNR persistence and in increasing academic attainments suggests that this programme could be used to complement other strategies that have been shown to have a positive effect on children's learning.
Factors in Organisational Environmental Management System Implementation – Developed vs. Developing Country Contexts

Country specificities and national cultures influence Environmental Management Systems (EMS) implementation and pro-environmental behaviour in organisations. Previous studies have focused on organisations in developed or emerging economies, creating a need to establish the extent to which findings are applicable to developing counterparts. This paper presents EMS implementation from a developing country perspective, reporting on EMS implementation factors (drivers, benefits, barriers) affecting Nigerian organisations’ pro-environmental behaviour, by analysing questionnaire responses from 136 Nigerian organisational respondents. Most commonly cited drivers were ‘environmental concern’ and ‘desire for improved organisational efficiency’. Key barriers were ‘cost of implementation/budget barriers’ and ‘regulatory agency bureaucracy’. Key benefits were ‘reduced environmental accidents and improved site safety’, ‘enhanced corporate image’ and ‘more efficient resource use’. To situate findings within a global construct, results were compared with previous studies in more developed economies. EMS implementation factors differed from those in more developed economies. Plausible explanations for differences are discussed.
Quantitative proteomic analysis of host responses triggered by Mycobacterium tuberculosis infection in human macrophage cells

Macrophages are primary host of Mycobacterium tuberculosis (M.tb) and the central effector of in vivo innate immune responses against bacteria. Though the interaction between macrophages and mycobacteria has been widely investigated, the molecular mechanisms of M.tb pathogenesis in macrophages are still not clear. In this work, we investigated the altered protein expression profiles of macrophages after virulent H37Rv strain and avirulent H37Ra strain infection by tandem mass tag-based quantitative proteomics. Among 6762 identified proteins of macrophages, the expression levels of 235 proteins were significantly altered, which is supposed to be related to the infection of different strains. By bioinformatics analysis at systems level, we found that these proteins are mainly involved in the biological process of apoptosis, blood coagulation, oxidative phosphorylation, and others. The enormous variation in protein profiles between macrophages infected with H37Ra and H37Rv suggests the existence of four different immunity mechanisms that decide the fates of macrophages and M.tb. These data may provide a better understanding of M.tb pathogenesis within the host, which contributes to the prevention and clinical treatment of tuberculosis.
The Origins of Political Attitudes and Behaviours: An Analysis Using Twins

Abstract. This article provides a behaviour genetic heritability analysis of several political issues, including social and economic conservatism, general interest in politics, attitudes toward the major Canadian federal parties, federal party identification and national vote choice. Substantial genetic effects were found for four of six political attitude scales, with heritability values ranging from 41 per cent to 73 per cent. Genetic effects are also reported for several individual items (including feelings toward the major federal parties, party identification and vote choice), with heritabilities from 33 per cent to 62 per cent. The implications of these results for conventional political analyses are explored. Also presented is a theoretical interpretation of political heritability that is derived from an evolutionary perspective which suggests that political personalities or temperaments have evolved that are analogous to the heritable personality structures proposed by psychologists. Résumé. Cet article propose une analyse sur l'héritabilité de la génétique du comportement concernant plusieurs questions politiques, y compris le conservatisme social et économique, l'intérêt général pour la politique, les attitudes envers les principaux partis fédéraux canadiens, l'identification à un parti et le choix de vote au niveau national. Des effets génétiques notables ont été recensés pour quatre des échelles politiques d'attitude sur six, les taux d'héritabilité s'étendant de 41 pour cent à 73 pour cent. Des effets génétiques ont également été recensés pour plusieurs autres éléments étudiés (y compris les sentiments envers les principaux partis fédéraux, l'identification à un parti et le choix de vote), les taux d'héritabilité allant cette fois-ci de 33 pour cent à 62 pour cent. Cette étude explore l'incidence de ces résultats sur des analyses politiques conventionnelles. Il s'agit aussi d'une interprétation théorique de l'héritabilité politique dérivant d'une perspective évolutionnaire, qui suggère que les personnalités ou les tempéraments politiques ont évolué et que ces derniers sont analogues aux structures de personnalité transmissibles proposées par les psychologues.
Receiver Operating Characteristic Curve Analysis of Wechsler Memory Scale-Revised Scores in Epilepsy Surgery Candidates.

Wechsler Memory Scale-Revised (WMS-R) scores were analyzed in 82 epilepsy surgery candidates. These scores were used in combination with receiver operating characteristic (ROC) curves to classify patients with left temporal lobe (LTL; n = 47) and right temporal lobe (RTL; n = 35) seizure onset. Areas under the ROC curves indicated that separation of the LTL and RTL groups with most WMS-R subtest scores was minimal and close to chance level. Analyses of cutting scores revealed modest levels of classification with verbal memory measures such as the Logical Memory II subtest and with a score measuring the difference between Verbal and Visual Memory indexes. The results indicate that WMS-R scores used in isolation or in combination provide relatively poor discrimination of LTL and ML patients.
Special Education in Eastern Europe

IVAN Z. HOLOWINSKY, Ed.D Rutgers University The generally accepted view in the Soviet Union and Eastern Europe of mental retardation (MR) and learning disorders links severe intellectual and learning disorders with cerebral pathology. The Soviet view of MR suggests that it is related to a diffuse maldevelopment or defect of the cortical hemispheres which leads to pathological inertia of the central nervous system. This condition (MR) is known in Soviet literature as oligophrenia. Pevzner (1973) suggested that there are five forms of oligophrenia. The first is characterized by diffuse maldevelopment of the cortical hemispheres without serious neurological complications. The second involves a cortical
Functional Analysis of saxophone, the Drosophila Gene Encoding the BMP Type I Receptor Ortholog of Human ALK1/ACVRL1 and ACVR1/ALK2

In metazoans, bone morphogenetic proteins (BMPs) direct a myriad of developmental and adult homeostatic events through their heterotetrameric type I and type II receptor complexes. We examined 3 existing and 12 newly generated mutations in the Drosophila type I receptor gene, saxophone (sax), the ortholog of the human Activin Receptor-Like Kinase1 and -2 (ALK1/ACVRL1 and ALK2/ACVR1) genes. Our genetic analyses identified two distinct classes of sax alleles. The first class consists of homozygous viable gain-of-function (GOF) alleles that exhibit (1) synthetic lethality in combination with mutations in BMP pathway components, and (2) significant maternal effect lethality that can be rescued by an increased dosage of the BMP encoding gene, dpp+. In contrast, the second class consists of alleles that are recessive lethal and do not exhibit lethality in combination with mutations in other BMP pathway components. The alleles in this second class are clearly loss-of-function (LOF) with both complete and partial loss-of-function mutations represented. We find that one allele in the second class of recessive lethals exhibits dominant-negative behavior, albeit distinct from the GOF activity of the first class of viable alleles. On the basis of the fact that the first class of viable alleles can be reverted to lethality and on our ability to independently generate recessive lethal sax mutations, our analysis demonstrates that sax is an essential gene. Consistent with this conclusion, we find that a normal sax transcript is produced by saxP, a viable allele previously reported to be null, and that this allele can be reverted to lethality. Interestingly, we determine that two mutations in the first class of sax alleles show the same amino acid substitutions as mutations in the human receptors ALK1/ACVRl-1 and ACVR1/ALK2, responsible for cases of hereditary hemorrhagic telangiectasia type 2 (HHT2) and fibrodysplasia ossificans progressiva (FOP), respectively. Finally, the data presented here identify different functional requirements for the Sax receptor, support the proposal that Sax participates in a heteromeric receptor complex, and provide a mechanistic framework for future investigations into disease states that arise from defects in BMP/TGF-β signaling.
EMPIRICAL TESTS OF INTEREST-RELATIVE INVARIANTISM

Abstract According to Interest-Relative Invariantism, whether an agent knows that p, or possesses other sorts of epistemic properties or relations, is in part determined by the practical costs of being wrong about p. Recent studies in experimental philosophy have tested the claims of IRI. After critically discussing prior studies, we present the results of our own experiments that provide strong support for IRI. We discuss our results in light of complementary findings by other theorists, and address the challenge posed by a leading intellectualist alternative to our view.
Girls in Crisis: Newspaper Coverage of Adolescent Girls

Within the past several years, a growing body of scholars have exposed the media-generated crisis discourse surrounding youth — a discourse resulting in the construction/ definition of youth as a problem. Informed, in part, by this scholarship and grounded in frame theory, this study analyzes how U.S. newspapers covered the lives of adolescent girls during a particularly noteworthy period — the mid- to late 1990s, a time when a number of high-profile studies of girls' lives were published. During this time, the press, through the choice of topics covered, sources quoted, and overall organizing themes employed, perpetuated a discourse that constructed girls as a social problem in need of a solution. The authors argue that this construction of girls as weak and vulnerable denied them any form of agency and presented to the reader a dire situation in which adult intervention was needed to save these girls in crisis.
Environmental attitudes of young people in Turkey: effects of school type and gender

The purpose of this study is to investigate the effect of school type (private and public) and gender on sixth, seventh, eighth and tenth grade students’ attitudes toward the environment. A total of 1497 students (n = 765 girls; n = 715 boys; and n = 17 gender not provided) attending public (n = 603) and private schools (n = 892) located in Ankara participated in the study. A 45‐item Likert‐type questionnaire consisting of four dimensions, namely, awareness of environmental problems, national environmental problems, solutions to the problems and awareness of individual responsibility, was used to measure students’ environmental attitudes. A two‐way multivariate analysis of variance (MANOVA) was conducted to determine the effect of school type and gender on four dimensions of the environmental attitude questionnaire. Results showed that school type and gender had a significant effect on the collective dependent variables. Univariate ANOVAs indicated that mean scores on each dimension of the questionnaire were significantly different for students in public and private schools. Moreover, there was statistically significant mean difference between boys and girls with respect to scores on each dimension of the questionnaire. It is concluded as a result of the study that, although there are differences between categories of individuals, there is a widespread support for conservation of the environment among young people living in Ankara/Turkey.