Miracle-dz/UniFAR-FTUs huggingface dataset:
Inhibitory Effect of Fulvic Acid Extracted from Canadian Sphagnum Peat on Chemical Mediator Release by RBL-2H3 and KU812 Cells

Fulvic acid (FA) was extracted and purified from Canadian Sphagnum peat (CP-FA) and characterized by using an element analysis meter, Fourier transform infrared (FT-IR) spectroscopy, electron spin resonance (ESR) spectroscopy, and 13C-nuclear magnetic resonance (13C-NMR) spectroscopy. To investigate the antiallergic effect of CP-FA, we incubated rat basophilic leukemia (RBL-2H3) cells with 0.001–10.0 μg/ml of CP-FA and determined the β-hexosaminidase release inhibition at different response stages. The intracellular calcium [Ca2+] i level was also determined by using Fluo 3-AM, a calcium-specific fluorescent probe, and the cytotoxicity of CP-FA was determined by the 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. The results revealed that RBL-2H3 cells incubated for 48 h with 0.001–10.0 μg/ml of CP-FA did not show any decreased viability. CP-FA inhibited the β-hexosaminidase release by IgE-sensitized, antigen-stimulated RBL-2H3 cells at the antigen-antibody binding stage and the antibody-receptor binding stage. CP-FA also inhibited histamine release from A23187 plus PMA- or compound 48/80-stimulated KU812 cells. Furthermore, there was a decrease in the intracellular [Ca2+] i level in IgE-sensitized cells incubated with CP-FA and stimulated with antigen. Our results show that CP-FA may be useful for the treatment or prevention of allergic diseases.
National Report on Social Equity in VET 2013

The ‘National report on social equity in VET 2013’ provides comprehensive information and analysis on the participation, achievement and transitions from the Australian vocational education and training (VET) system for learner groups which have been identified as at risk of disadvantage. Overall, the report portrays VET as providing a diverse range of training opportunities for individuals experiencing a wide range of life circumstances. The report includes separate chapters on: Indigenous Australians; people with a disability; people from culturally and linguistically diverse backgrounds; people living in remote areas; people from low socio-economic status (SES) backgrounds; issues relating to gender; and those for whom VET may be seen as offering a ‘second chance’. Each chapter includes national and state and territory breakdowns of 2011 quantitative data relating to participation, achievement and transitions, with an accompanying analysis. This is the first report of its kind for Australia. It has been developed by the Australian Council for Educational Research (ACER) and Monash University’s Centre for the Economics of Education and Training (CEET) for the National VET Equity Advisory Council (NVEAC) through a collaborative process with input from representatives of all state and territory governments, the Australian Government and the National Centre for Vocational Education Research (NCVER). Underpinning the report is the NVEAC VET Equity Outcomes Framework, developed by the Council as a comprehensive set of measures for monitoring VET participation and outcomes for learners from six identified equity groups. 2011 VET Equity Outcomes Framework measures are included in the executive summary of the report.
Private Saving and Terms of Trade Shocks: Evidence from Developing Countries

The relationship between temporary terms of trade shocks and household saving in developing countries is examined. It is first shown that, from a theoretical standpoint, this relationship is ambiguous: private saving may rise or fall in response to a transitory terms of trade shock, depending on the values of the intertemporal elasticity of substitution and the intratemporal elasticity of substitution between traded and nontraded goods. Empirical estimates of these two parameters are obtained using data from a sample of 13 developing countries, and then used to draw implications for the response of private saving to transitory terms of trade shocks.
Effectiveness of monetary policy and limited asset market participation: Neoclassical versus Keynesian effects

This paper investigates the effects of limited asset market participation on the effectiveness of monetary policy in a New Keynesian Dynamic Stochastic General Equilibrium model. Although an increase in consumers who cannot access financial markets reduces the effects of interest rate policies through consumption inter-temporal allocation (neoclassical or permanent income effect), we find an opposite result: monetary policy becomes more effective as the degree of financial market participation falls. The reason has a very Keynesian flavor.
Tap and Shoot Segmentation

We present a new segmentation method that leverages latent photographic information available at the moment of taking pictures. Photography on a portable device is often done by tapping to focus before shooting the picture. This tap-and-shoot interaction for photography not only specifies the region of interest but also yields useful focus/defocus cues for image segmentation. However, most of the previous interactive segmentation methods address the problem of image segmentation in a post-processing scenario without considering the action of taking pictures. We propose a learning-based approach to this new tap-and-shoot scenario of interactive segmentation. The experimental results on various datasets show that, by training a deep convolutional network to integrate the selection and focus/defocus cues, our method can achieve higher segmentation accuracy in comparison with existing interactive segmentation methods.
The Reliability of EMU Fiscal Indicators: Risks and Safeguards

The reliability of EMUi? ½s fiscal indicators has been questioned by recent episodes of large upward deficit revisions. This paper discusses the causes of such revisions in order to identify ways to improve monitoring. The computation of EMUi? ½s deficit indicator involves the assessment of accrued revenue and expenditure and the identification of transactions in financial assets. Both can open margins for opportunistic accounting. However, crosschecks between deficit and changes in gross nominal debt (the other fiscal indicator used in EMU) can reduce the scope for window dressing. Simple comparison of deficit and changes in debt can readily spotlight large inconsistencies in fiscal data. Nevertheless, consistency checks must go deeper than simple comparison, since different items in the reconciliation account between deficit and change in debt can offset each other. Econometric evidence suggests that such offset may indeed have been used to reduce the visibility of deficit-specific window dressing. Attention to the quality of statistics has increased in recent years, also in the context of the reform of the Stability and Growth Pact. In this context, the paper argues that detailed analysis of the reconciliation account between deficit and change in debt is crucial to the effectiveness of monitoring.
Markov-Switching Estimation of Spatial Maize Price Transmission Processes between Tanzania and Kenya

We discuss the Markov-switching vector au toregressive (MS-VAR) class of nonlinear time series models that can be used to analyze recurring discrete structural changes in time series. Hamilton's (1989) seminal Markov switching (MS) model of the U.S. business cy cle triggered considerable interest in the MS approach in economics. Most empirical appli cations to date have focused on the business cy cle and financial markets, but we see potential for MS-VAR models in agricultural economics, for example, in price transmission analysis. In the following, we first provide an overview of the MS-VAR framework. We then present an illustrative application to maize price trans mission between Tanzania and Kenya. The article closes with a discussion of strengths, weaknesses, and potential uses of the MS-VAR approach in price transmission analysis.
Does minimum wage affect hours worked of paid employment in Indonesia

Purpose - – The purpose of this paper is to examine the effect of a change in minimum wage on hours worked of paid employment in Indonesia. This study used the Indonesian Labor Force Survey (Sakernas) data from 1996 to 2003. Design/methodology/approach - – This study employs Bourguignon-Fournier-Gurgand two-step procedure of sample selection corrections based on a multinomial logit model for a potential selection bias from a non-random sample. This study extends the specification by examining the effects of minimum wage on hours worked of paid employment separately across individuals in different groups of gender (male-female workers) and residences (urban-rural areas). Findings - – This study generally found that an increase in the minimum wage increases hours worked of the existing paid employees. The effects of the minimum wage on hours worked are stronger for female workers than male workers particularly in urban areas due to that female workers, particularly in urban areas, are mostly employed in industries which contain more low-wage workers. Comparing residences, the minimum wage coefficient in rural areas is slightly higher because of the structural transformation in Indonesia marked by a shift in employment from the agriculture sector to the other sectors that require more working hours. Originality/value - – The empirical studies of the effect of minimum wage on hours worked in developing countries are very limited. This study contributes to the literature by employing the sample selection corrections based on a multinomial logit for a potential selection bias from a non-random sample This study also extends the hours worked specification by analyzing the effects of minimum wage on hours worked separately across individuals in different groups of workers, in terms of gender (male-female workers) and their residences (urban-rural areas).
The value of the psychological capital of immigrant entrepreneurs

Immigrant entrepreneurs have always played a critical role in the economies of countries around the world. Although considerable attention has been devoted to the importance of economic and financial capital, we examine three overlooked forms of capital that may enhance the success of immigrant entrepreneurs: human, social, and psychological capital. Special attention is given to the positive psychological capital strengths of hope, self-efficacy/confidence, optimism, and resilience. We propose that successful immigrant entrepreneurs are those who not only possess, but also seek to further develop and leverage this newly recognised form of capital in themselves and their associates.
"That's what you do for people you love": A qualitative study of social support and recovery from a musculoskeletal injury

Background Social support has been identified as a significant factor in facilitating better health outcomes following injury. However, research has primarily focused on the role of social support from the perspective of the person experiencing an injury. Limited research has examined the experiences of the family members and friends of a person with injury. This study aims to explore the perceptions and experiences of social support and recovery following a transport-related musculoskeletal injury (MSI) in a population of injured persons and their family members and friends. Methods This study was conducted using a phenomenological qualitative research design. In-depth semi-structured interviews were conducted with ten persons with MSI, recruited via the Transport Accident Commission (TAC) in Victoria, Australia. Seven family members and friends were also interviewed. The data was analysed using constant comparative method and thematic analysis. Results Several themes were identified including: (1) key sources and types of support received, (2) relationship development and (3) challenges of providing and receiving support. Participants with MSI reported stories about how the social network provided emotional and tangible support. Family members and friends confirmed the supportive acts provided to the participants with MSI. Positive iterative changes in relationships were reported by the participants with MSI. Participants with MSI, their family members and friends described several difficulties including loss of independence, feeling like a burden, and the impact of caring on health and well-being. Conclusions The role of social support is complex given the multitude of people involved in the recovery process. The findings of this study suggest that persons with MSI may benefit from support groups and maintenance of existing support networks. Furthermore, family members and friends engaged in the recovery process may benefit from support in this role.
Online Marketing: A Boon or Bane for Business in Singapore?

This paper examines the impact of e-commerce through online marketing among the multi-national corporations in Singapore. A survey was carried out to examine the differences between online and traditional marketing strategies, to explore the possibility of online marketing replacing traditional marketing, and consequently, the future of online marketing in Singapore. The findings reveal that MNCs do adopt different marketing strategies, both online and offline, in aspects of product, price, place, promotion, people, physical evidence and promotion. Results indicate that online marketing is still in its infancy in Singapore. Although most MNCs are not selling online but some plan to do so within twelve months.
Exposure study on chemosensory effects of epsilon-caprolactam in the low concentration range.

OBJECTIVE Aim of the study was to examine possible chemosensory effects of epsilon-caprolactam in the low concentration range relevant to indoor environmental conditions. METHODS Twenty healthy subjects (10 male, 10 female) aged from 21 to 38 years were exposed for 6 h, respectively, to 0, 0.15, 0.5 and 5 mg/m3 epsilon-caprolactam vapours in a randomized and double-blind method. As a measure of trigeminal stimulation of the eye, blink frequency was video-recorded four times per day and evaluated by using a new semi-automatic, computer-assisted method compared to baseline recording and manual counting. Digital slit lamp photographs were taken at the same time to examine conjunctival hyperaemia. A standardized ophthalmologic grading scale was used to measure redness of the eyes objectively. Active anterior rhinomanometry compared nasal resistance before and after exposure. Subjective ratings of discomfort and mental orientation were assessed using the German version of the Swedish Performance Evaluation system (SPES). As a measure of personality traits, positive and negative affectivity was determined (PANAS). RESULTS Six hour exposures to epsilon-caprolactam revealed no significant dose-response relationship concerning blink frequency, nasal resistance and redness of the bulbar conjunctiva. Subjective ratings of discomfort (sum scores) significantly increased only at the highest concentration of 5 mg/m3. However, the increase in discomfort was only moderate, ranging between "not at all" and "somewhat". Significant increases of the subjective detection of malodour (subscore) already occurred at 0.15 mg/m3, showing no adaptation over time. Irritation of the eyes or upper airways was not reported. CONCLUSIONS Exposure to epsilon-caprolactam vapour did not elicit any acute health effects in a concentration range up to 0.5 mg/m3. Even at the highest concentration of 5 mg/m3, we could only find a slight increase in subjective symptoms, mainly due to an unincisive increase of perception of malodour.
Effect of Financial Development on Economic Growth: Does Inflation Matter? Time Series Evidence from the UEMOA Countries

An important issue in the finance and growth literature is whether the strength of the relationship between finance and growth may depend on inflation rate. This paper uses time-series data to examine this evidence for seven African countries. The technique of principal component analysis is used to construct an overall index for financial development. This summary measure is used to estimate nonlinear growth equations. The empirical findings did not provide significant evidence of nonlinearity in the finance-growth relationship. Financial development has no significant effect on economic growth regardless of the level of inflation.
Radiocarbon Variations from Tasmanian Conifers: Results from Three Early Holocene Logs

Dendrochronological studies are being carried out on two conifer species in the Stanley River area of western Tasmania. The chronology for Huon pine (Lagarostrobos franklinii), with living trees up to 1400 yr old, extends back to 571 bc. Living celery-top pine (Phyllocladus aspleniifolius) trees are up to 500 yr old. Apart from living or recently felled trees, sections have been taken from 350 subfossil logs preserved in floodplain sediments. They range in age from >38 ka to modern, with good coverage for the periods 9–3.5 ka and from 2.5 ka to the present. We report here on 14C measurements of decadal samples from three early Holocene logs, between 10 and 9 ka bp, providing short (ca. 300-yr) records of atmospheric 14C variations when plotted against ring numbers. The southern hemisphere data from Tasmania can be compared and wiggle-matched with published 14C calibration curves from German oak and pine. One set of measurements covers the period, ca. 9280–8990 cal bp, overlapping the link between the Hohenheim “Main 9” and middle Holocene master oak chronologies. The other sets of measurements from Tasmania coincide; they span the period, ca. 9840–9480 cal bp, overlapping the end of the German Preboreal pine and the beginning of the oak chronologies. Our measurements confirm that this part of the calibration curve is a gently sloping 14C-age plateau (ca. 8900–8700 bp, between 10,000 and 9500 cal bp), and suggest interhemispheric 14C differences close to zero.
A Focus on Macitentan in the Treatment of Pulmonary Arterial Hypertension

The approval of macitentan has increased the number of pharmacological treatments of pulmonary arterial hypertension (PAH). Here, we review the effect on PAH of macitentan compared to other endothelin receptor antagonists. Drugs targeting the endothelin (ET) pathway include the selective ETA receptor antagonist ambrisentan, the ETA /ETB receptor antagonists, bosentan and macitentan, which were recently approved for PAH treatment. Macitentan exhibits higher antagonistic potency than bosentan and ambrisentan in pulmonary smooth muscle cells. Compared to ambrisentan and bosentan, macitentan has a longer duration of action, reflected by the longer half-life, as well as pharmacodynamics attributed to its active metabolite, ACT-132577. The efficacy of macitentan on PAH was investigated in the phase III SERAPHIN trial (NCT00660179). Macitentan significantly reduced morbidity and mortality. It improved the 6-min. walk distance (6MWD) among PAH patients. In the AMB-320/321-E (NCT00578786) study, ambrisentan improved exercise capacity. In the EARLY study (NCT00091715), bosentan showed improvements in 6MWD which were not statistically significant. Bosentan had an effect on PAH in patients with Eisenmenger syndrome (ES) in the BREATHE-5 study (NCT00367770), while macitentan did not improve 6MWD in these patients, but there are differences regarding study size and functional class, and that 30% of the patients treated with macitentan were already in treatment with a phosphodiesterase type 5 inhibitor. Macitentan revealed a lower risk of developing peripheral oedema and hepatotoxicity in the SERAPHIN study. In summary, macitentan has an efficiency comparable to bosentan and ambrisentan in the treatment of PAH. Patients treated with macitentan exhibited less adverse effects compared to bosentan and ambrisentan. In patients with PAH associated with ES, the trials with bosentan and macitentan do not seem comparable, and it needs to be clarified whether these drugs are effective when administered as part of a combination treatment in this condition.
Pulmonary function in thalassaemia major and its correlation with body iron stores

This study compared pulmonary function tests (PFTs) with cardiac, pancreatic and liver iron in 76 thalassemia major (TM) patients. Restrictive lung disease was observed in 16%, hyperinflation in 32% and abnormal diffusing capacity in 3%. While no patients met Global Initiative for Chronic Lung Disease criteria for airways obstruction, there were indicators of small airways disease and air trapping. PFTs did not correlate with somatic iron burden, blood counts or haemolysis. Restrictive lung disease was associated with inflammation. We conclude that TM patients have pulmonary abnormalities consistent with small airways obstruction. Restrictive disease and impaired diffusion are less common.
The Nerves of State: Taxation and the Financing of the English State, 1558-1714

National taxation and national finances in England, 1558-1714 spending and borrowing the customs Demesne revenues - prerogative income and concealed taxes parliamentary taxes the politics of taxation - the economic effects of taxation the politics of taxation - legality, legitimacy and liberty tax collection and the taxpayer taxing the people - the limits of the possible in England, 1558-1714 documents.
Financial Statements and Positive Accounting Theory. The Early Contribution of Aldo Amaduzzi

This paper examines some of the accounting ideas that were developed in the late 1940s by an Italian professor, Aldo Amaduzzi, with regards to positive accounting studies and the content of financial statements. The paper briefly reviews the aim, methodological assumptions and key findings of the so-called 'positive accounting theory' based on the works of the Rochester school of accounting. A content analysis of the early work of Amaduzzi, in relation to his view that the contents of financial statements can be seen as the equilibrium outcome of a conflict of interests between corporate stakeholders, shows that many of the methodological issues on accounting theory stressed by the 'Rochester school of accounting' were raised by Amaduzzi (1947, 1949). The paper concludes that although some key differences between the two approaches do exist, Amaduzzi may be considered as a forerunner of positive accounting theory.
A Comparative Analysis of the Public Spending Efficiency of the New EU Member States: A DEA Approach

This paper provides an analysis of the performance and efficiency of the public sector in the European Union (EU). Using composite indicators and data envelopment analysis, we focus on the new EU member countries, which were involved over the past decade in the accession and integration process. Results of the analysis indicate that, unlike "old" EU members, which invested more in sectors such as education or health, countries in Central and Eastern Europe, the "new" EU member states, have directed public resources mainly toward the performance of the government sectors. However, greater efficiency has been achieved precisely in those areas where they have invested less.
Determinants of Dividend with Industry-Wise Effect – Evidence from KSE 100 Index

This research have identified the industry-wise effect of dividend policy among non-financial listed companies of KSE 100 Index. For this purpose data from 2006 to 2011 for 53 companies of different industries i.e. Fuel and Energy Sector, Chemicals Sector, Cement Sector, Engineering Sector, Textiles Sector and Transport and Communication Sector have been taken. Multiple Regression Analysis has been used to identify the prominent determinant of Dividend and Industry effect was captured through incorporating six dummy variables for said industries. Results highlighted that apart from profitability most powerful determinant of dividend there are other factors of life cycle, tangibility of assets are prominent whereas capital structure, size of firm and cash flows per share is not significant determinant of dividend. Apart from these variable, Industry-wise effect shows that all the above significant determinants remains significant within industry except textile sector.