Miracle-dz/UniFAR-FTUs huggingface dataset:
Dental ontogeny and replacement in Pliosauridae

Dental morphology and patterns of tooth replacement in representatives of the clade Pliosauridae (Reptilia, Sauropterygia) are evaluated in detail. The jaws of one basal (Thalassiodracon hawkinsii) and two derived species (Pliosaurus carpenteri, Pliosaurus kevani) were visualized by μCT scans, and the ontogenetic patterns, or ‘movement paths’, of replacement teeth could be mapped. Other specimens (Peloneustes philarchus and Pliosaurus westbuyensis) with well-preserved jaws containing functional and replacement teeth in situ were also examined directly, and waves of tooth replacement could be inferred from the degree of in situ tooth development and the fusion between functional and replacement alveoli. The analysis revealed symmetrical tooth eruption over the medial axis throughout the length of the jaw in the basal pliosaurid Thalassiodracon. By contrast, symmetrical tooth eruption patterns occur only along the anterior sections of the jaws of derived pliosaurids. In Pliosaurus, replacement schedules differ in the anterior and posterior portions of the jaws and appear to correlate with differences in tooth morphology and symmetrical replacement. The anterior teeth exhibit longer replacement cycle periods and symmetrical replacement, while shorter cycle periods and asymmetry are seen posteriorly. A longer period suggests slower replacement and is characteristic of large, specialized caniniform teeth in the longer snouted Late Jurassic taxa. Smaller posterior teeth have a shorter period and therefore a faster replacement cycle. The transition from long to short replacement period over the length of the jaw is thought to account for the loss of symmetry. This differentiation could relate to differential tooth function and a type of heterodonty. We therefore propose a new model of pliosaurid tooth replacement patterns and present it in a phylogenetic context.
A Cross-Layer Scheme for Solving Hidden Device Problem in IEEE 802.15.4 Wireless Sensor Networks

The IEEE 802.15. 4 standard is designed to achieve low-power transmissions in low-rate and short-distance wireless personal area networks (WPANs). For the sake of reducing the control overheads, the modified CSMA/CA protocol used by 802.15. 4 does not have the hidden device protection mechanism, such as RTS/CTS mechanism. Previous studies indicated that the probability of any two devices in an infrastructure network unheard of each other is around 41%. Therefore, the hidden device problem (HDP) results in inefficient data transmission and serious power consumption issues in WPAN. In this paper, we propose a cross-layer detection and allocation (CL-DNA) scheme to solve the HDP in IEEE 802.15. 4 without the cost of extra control overhead in data transmissions. The proposed scheme detects relationships of hidden devices based on the overlapped signals and then allocates the hidden devices into distinct subperiods for transmissions. Simulation results validated by mathematical analysis show that the proposed scheme significantly improves the goodput with the reduction in power consumption.
An investigation of the linkage between relationship status (single vs. partnered), identity dimensions and self-construals in a sample of Polish young adults

The aim of this exploratory cross-sectional study was to examine the associations among relationship status, identity processes, and self-construals among Polish young adults. The theoretical framework of the study consisted of Erikson’s psychosocial theory of human development (Erikson, 1963; 1968; 1980), the dual-cycle model of identity formation (Luyckx, Goossens, & Soenens, 2006), and the concept of independent and interdependent selfconstruals. A total of 291 university students (155 females and 136 males) aged 20–25 completed the Dimensions of Identity Development Scale (DIDS; Luyckx, Schwartz et al., 2008) (Polish adaptation – Brzezińska & Piotrowski, 2010a) and Self-Construal Scale (SCS; Singelis, 1994) (Polish adaptation – Pilarska, 2014). Results showed that single individuals scored higher on exploration in breadth, exploration in depth, and ruminative exploration, and lower on commitment making and identification with commitment than did partnered individuals. Further, single and partnered individuals did not differ in the area of independent and interdependent self-construals. Discriminant function analysis revealed that especially ruminative exploration and exploration in breadth were important variables for discriminating single from partnered status.
Correlation between MRI and Operative Findings in Bell's Palsy and Ramsay Hunt Syndrome

Purpose To investigate the correlation between gadolinium enhanced magnetic resonance image (MRI) results and surgical findings of facial nerves in Bell's palsy and Ramsay Hunt syndrome. Materials and Methods From 1995 to 2004, MRI was performed on 13 patients with Bell's palsy or Ramsay Hunt syndrome, who were offered with surgical decompression of the facial nerve through the middle cranial fossa approach. Gadolinium enhanced MRI was performed on all patients and the enhancement of the facial nerve was evaluated by radiology specialists. Operative findings including the degree of the facial nerve segment swelling were examined. Furthermore, the time interval from the onset of palsy to surgery was evaluated. Results Swelling of facial nerve segments was found in patients with enhanced facial nerves from MRI. The swelling of the facial nerve in the labyrinthine segment in particular was identified in all patients with enhanced labyrinthine segments in MRI. The intraoperative swelling of geniculate ganglion of facial nerve was found in 78% of patients with enhanced facial segment in MRI (p = 0.01). The intraoperative swelling of tympanic segment was observed from fourth to ninth weeks after the onset of palsy. Conclusion MRI enhancement of facial nerves in Bell's palsy and Ramsay Hunt syndrome is associated with the extent of intratemporal lesions of facial nerves, especially in the labyrinthine segment.
Amyloid beta 1 – 42 and the phoshorylated tau threonine 231 in brains of aged cynomolgus monkeys ( Macaca fascicularis )

1 Department of Experimental Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark 2 Department of Anatomy, Physiology and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor, Indonesia 3 Department of Neuroscience and Pharmacology, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark 4 Center for Functionally Integrative Neuroscience, University of Aarhus, Aarhus, Denmark 5 Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA 6 Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada 7 Primate Research Center, Bogor Agricultural University, Bogor, Indonesia 8 Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, TX, USA 9 Department of Pathology, Faculty of Veterinary Medicine, University of Gajah Mada, Yogyakarta, Indonesia 10 Division of Pathology, Department of Clinic, Reproduction and Pathology, Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor, Indonesia
A dairy product fermented by lactobacilli cancels the adverse effects of hypochlorhydria induced by a proton pump inhibitor on bone metabolism in growing rats

The purpose of the present study is to investigate the effects of hypochlorhydria induced by proton pump inhibitor (PPI) administration and intake of a dairy product fermented by lactobacilli (DFL) on bone metabolism in growing rats. Male rats, aged 3 weeks, were divided into two groups: a control group fed a casein-based diet and a group fed a DFL-based diet. Each group was fed its respective experimental diets for 9 d. At day 5 of the feeding period, each group was divided into two subgroups: one that received a saline injection and one that received a PPI injection. Rats were subcutaneously administered saline or PPI for 5 d. Faecal Ca excretion was determined from day 6 to day 9. At the end of the experiment, plasma and femurs were collected. Administration of PPI significantly decreased bone mineral density (shown by X-ray computerised tomography) and bone strength (shown by a three-point bending test) in the control group. Plasma osteocalcin, type I collagen C-telopeptides, 1,25-dihydroxyvitamin D and parathyroid hormone concentrations were elevated by PPI administration in the control group. Faecal Ca excretion and urinary P excretion in the control group were remarkably increased by PPI administration. On the other hand, these adverse effects of PPI were not observed in the DFL group. These results suggest that hypochlorhydria-induced bone loss may result from high bone turnover induced by secondary hyperparathyroidism due to Ca malabsorption and that DFL intake cancels these adverse effects probably via improving Ca malabsorption in growing rats.
Search in Imperfect Information Games Using Online Monte Carlo Counterfactual Regret Minimization

Online search in games has always been a core interest of artificial intelligence. Advances made in search for perfect information games (such as Chess, Checkers, Go, and Backgammon) have led to AI capable of defeating the world's top human experts. Search in imperfect information games (such as Poker, Bridge, and Skat) is significantly more challenging due to the complexities introduced by hidden information. In this paper, we present Online Outcome Sampling (OOS), the first imperfect information search algorithm that is guaranteed to converge to an equilibrium strategy in two-player zero-sum games. We show that OOS avoids common problems encountered by existing search algorithms and we experimentally evaluate its convergence rate and practical performance against benchmark strategies in Liar's Dice and a variant of Goofspiel. We show that unlike with Information Set Monte Carlo Tree Search (ISMCTS) the exploitability of the strategies produced by OOS decreases as the amount of search time increases. In practice, OOS performs as well as ISMCTS in head-to-head play while producing strategies with lower exploitability given the same search time.
An Ounce of Preventative Research Design Is Worth a Ton of Statistical Analysis Cure

This response addresses the data analysis issues raised by Wierenga and van Bruggen (1998) concerning Massetti (1998). Their analysis suggestions were performed and resulted in no significant differences between the treatment conditions. However, these analyses are misleading because of normality and variance problems present in Massetti’s dataset. Specifically, not controlling for individual performance differences in ideational fluency ability during experimentation created the need for the complex, but appropriate, analysis approach used in Massetti. This response further suggests that ideational fluency be included as an independent factor in future research on individual creativity support systems.
Evaluating the Financial Impact of Branding Using Trademarks: A Framework and Empirical Evidence

Firms spend considerable efforts to build brand awareness and associations among consumers. Yet there is a limited understanding of the financial returns of such investments. In this article, the authors present a framework that uses trademarks as measures of firms' branding efforts. They classify trademarks into two categories—brand-identification trademarks and brand-association trademarks—and propose that they are indicators of firm efforts to build brand awareness and associations among consumers, respectively. The authors then evaluate the chain of effects linking such assets with metrics of firms' financial value. A longitudinal analysis of data collected from secondary sources reveals that the stock (i.e., total number) of brand-association trademarks available to firms in time period t increases their cash flow, Tobin's q, return on assets, and stock returns and reduces their cash-flow variability in period t + 1. Furthermore, the authors observe that the stock of brand-identification trademarks owned by firms in period t − 1 influences the effects of brand-association trademarks on cash flow, Tobin's q, and stock returns. Together, these findings provide useful insights into the financial value of branding.
Rear Seat Restraint System Optimization for Older Children in Frontal Crashes

Objective: Analyses of crash injury data have shown that injury risk increases when children transition from belt-positioning boosters to the vehicle seat belt alone. The objective of this study is to investigate how to improve the restraint environment for these children. Methods: A parametric analysis was conducted to investigate the effects of body size, seat belt anchorage locations, and rear seat design parameters on the injury risks in frontal crashes of children aged 6 to 12 years old using a newly developed parametric child anthropomorphic test dummy (ATD) model. Restraint design optimizations were also conducted to obtain ranges of optimal restraint system configurations that provide best protections for 6-, 9-, and 12-year-old children. Results: Simulation results showed that child body size was the dominant factor affecting outcome measures. In general, lower and more rearward D-rings (upper belt anchorages), higher and more forward lap belt anchorages, and shorter, stiffer, and thinner seat cushions were associated with improved restraint performance. In these simulations, children with smaller body sizes require more-forward D-rings, inboard anchors, and outboard anchor locations to avoid submarining. However, these anchorage locations increase head excursions relative to more-rearward anchorages. Conclusions: The balance of reducing head and knee excursions and preventing submarining indicates that an optimization approach is necessary to improve protection for 6- to 12-year-old child occupants. The findings of this study provided design guidelines for future rear seat restraint system. Supplemental materials are available for this article. Go to the publisher's online edition of Traffic Injury Prevention to view the supplemental file.
On the Functional Forms and Stability of Money Demand: The U.S., Japan and Australia

We find strong evidence for the stability of money demand of a semi-log form for the U.S., a log-log form for Japan and a semi-log form for Australia. This implies that there could be no finite satiation on the money demand curve as the nominal interest rate approaches zero and continue to stay near zero for a long period of time. The results support Friedman’s (1969) zero nominal interest rate rule. We also estimate the welfare cost of inflation using the functions derived by Lucas (2000) from Bailey’s (1956) definition of the welfare cost.
Age-specific differences in influenza virus type and subtype distribution in the 2012/2013 season in 12 European countries

SUMMARY The epidemiology of seasonal influenza is influenced by age. During the influenza season, the European Influenza Surveillance Network (EISN) reports weekly virological and syndromic surveillance data [mostly influenza-like illness (ILI)] based on national networks of sentinel primary-care providers. Aggregated numbers by age group are available for ILI, but not linked to the virological data. At the end of the influenza season 2012/2013, all EISN laboratories were invited to submit a subset of their virological data for this season, including information on age. The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups. Thus, in cases aged 5–14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses. This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading. Surveillance at the European level would benefit from the reporting of age-specific influenza data.
Subcellular Localization of Frizzled Receptors, Mediated by Their Cytoplasmic Tails, Regulates Signaling Pathway Specificity

The Frizzled (Fz; called here Fz1) and Fz2 receptors have distinct signaling specificities activating either the canonical Wnt/β-catenin pathway or Fz/planar cell polarity (PCP) signaling in Drosophila. The regulation of signaling specificity remains largely obscure. We show that Fz1 and Fz2 have different subcellular localizations in imaginal disc epithelia, with Fz1 localizing preferentially to apical junctional complexes, and Fz2 being evenly distributed basolaterally. The subcellular localization difference directly contributes to the signaling specificity outcome. Whereas apical localization favors Fz/PCP signaling, it interferes with canonical Wnt/β-catenin signaling. Receptor localization is mediated by sequences in the cytoplasmic tail of Fz2 that appear to block apical accumulation. Based on these data, we propose that subcellular Fz localization, through the association with other membrane proteins, is a critical aspect in regulating the signaling specificity within the Wnt/Fz signaling pathways.
Determination of Acceptor Concentration, Depletion Width, Donor Level Movement and Sensitivity Factor of ZnO on Diamond Heterojunction under UV Illumination

The concentration of acceptor carriers, depletion width, magnitude of donor level movement as well as the sensitivity factor are determined from the UV response of a heterojunction consisting of ZnO on type IIb diamond. From the comparison of the I-V measurements in dark condition and under UV illumination we show that the acceptor concentration (∼1017 cm−3) can be estimated from p-n junction properties. The depletion width of the heterojunction is calculated and is shown to extend farther into the ZnO region in dark condition. Under UV illumination, the depletion width shrinks but penetrates both materials equally. The ultraviolet illumination causes the donor level to move closer to the conduction band by about 50 meV suggesting that band bending is reduced to allow more electrons to flow from the intrinsically n-type ZnO. The sensitivity factor of the device calculated from the change of threshold voltages, the ratio of dark and photocurrents and identity factor is consistent with experimental data.
Dissociation of response conflict, attentional selection, and expectancy with functional magnetic resonance imaging.

Two different attentional networks have been associated with visuospatial attention and conflict resolution. In most situations either one of the two networks is active or both are increased in activity together. By using functional magnetic resonance imaging and a flanker task, we show conditions in which one network (anterior attention system) is increased in activity whereas the other (visuospatial attention system) is reduced, showing that attentional conflict and selection are separate aspects of attention. Further, we distinguish between neural systems involved in different forms of conflict. Specifically, we dissociate patterns of activity in the basal ganglia and insula cortex during simple violations in expectancies (i.e., sudden changes in the frequency of an event) from patterns of activity in the anterior attention system specifically correlated with response conflict as evidenced by longer response latencies and more errors. These data provide a systems-level approach in understanding integrated attentional networks.
Karyopherins in nuclear pore biogenesis

The mechanisms that govern the assembly of nuclear pore complexes (NPCs) remain largely unknown. Here, we have established a role for karyopherins in this process. We show that the yeast karyopherin Kap121p functions in the targeting and assembly of the nucleoporin Nup53p into NPCs by recognizing a nuclear localization signal (NLS) in Nup53p. This karyopherin-mediated function can also be performed by the Kap95p–Kap60p complex if the Kap121p-binding domain of Nup53p is replaced by a classical NLS, suggesting a more general role for karyopherins in NPC assembly. At the NPC, neighboring nucleoporins bind to two regions in Nup53p. One nucleoporin, Nup170p, associates with a region of Nup53p that overlaps with the Kap121p binding site and we show that they compete for binding to Nup53p. We propose that once targeted to the NPC, dissociation of the Kap121p–Nup53p complex is driven by the interaction of Nup53p with Nup170p. At the NPC, Nup53p exists in two separate complexes, one of which is capable of interacting with Kap121p and another that is bound to Nup170p. We propose that fluctuations between these two states drive the binding and release of Kap121p from Nup53p, thus facilitating Kap121p's movement through the NPC.
Understanding the link between parental and adolescent depressive symptoms in families at-risk for type 2 diabetes

ii CHAPTER 1: INTRODUCTION.1 CHAPTER 2: CONNECTING DIABETES AND DEPRESSION.3 CHAPTER 3: METHODS.22 CHAPTER 4: RESULTS.29 CHAPTER 5: DISCUSSION.38 REFERENCES.47
The identification of dynamics of hydraulic servo system for remote cutting

For securing foundation technique of multi-axis hydraulic robot arm control, this paper deals with remote control of single hydraulic servo system. Identification of dynamics of single rod hydraulic servo system has done for control of position control of hydraulic cylinder. The unknown parameters of the linear element could be estimated by comparing the Bode plots of system's impulse response with them of model's response. However it is difficult to apply impulse response to real system. The dynamics is identified by applying signal compression method. After estimating unknown parameters, the response of the identified model from simulation is compared with the response from the real system. The estimated parameter of this paper will be used in control of multi-channel hydraulic servo system with sliding mode control with sliding perturbation observer(SMCSPO).
A unified framework for race analysis of asynchronous networks

A unified framework is developed for the study of asynchronous circuits of both gate and MOS type. A basic network model consisting of a directed graph and a set of vertex excitation functions is introduced. A race analysis model, using three values (0, 1, and x), is developed for studying state transitions in the network. It is shown that the results obtained using this model are equivalent to those using ternary simulation. It is also proved that the set of state variables can be reduced to a minimum size set of feedback variables, and the analysis still yields both the correct state transitions and output hazard information. Finally, it is shown how the general results above are applicable to both gate and MOS circuits.
DOUBLE PROFITS WITH A CONTROLLED TRAFFIC ZERO-TILL IRRIGATION FARMING SYSTEM ?

Many guidelines and recommendations for sugarcane farming are aimed at achieving a large number of ratoon crops. One of the reasons for this is that the replanting costs can be considerable when a field is conventionally tilled and replanted. Thus, delaying reestablishment makes financial sense provided the cost savings are greater than any yield and revenue penalties. An alternative is to introduce a controlled traffic and zero-till farming system (CTF), thereby lowering re-establishment costs and potentially allowing for fewer ratoon crops and more frequent green manure or break crops. A rigorous yield, sucrose content, costing and cash-flow analysis, based on published research findings and detailed costing of representative machinery, showed that a CTF system with only three ratoon crops was far more profitable than a conventional farming system involving eight ratoon crops and more intensive tillage operations. A doubling in profitability was shown when the yield benefits reported with break crops and the yield decline rates reported under conventional farming systems were included in the analysis. Substantial gains in water use productivity were also shown, up to nearly 80% improvement over a conventional farming system. Adoption of a CTF system with only three ratoon crops is therefore highly recommended and should be taken very seriously by decision-makers in the sugarcane industry.