Miracle-dz/UniFAR-FTUs huggingface dataset:
Mapping Assets: High Impact Practices and the First Year Experience

This paper describes a course called The First Year Experience: Mapping our Communities designed around a theme of asset mapping, which allowed us to organically integrate a number of pedagogical goals with a number of high-impact practices. The mapping metaphor extended from physical mapping of the university campus as a space to the mapping of academic and social resources, including mapping of the students’ sense of self and goals, their new environment and all the assets available to help them succeed. The theme of asset mapping also encompassed different world views and the concepts of perspective and positionality to provide students with a critical perspective on their own understanding and its limits. Our research assesses the success of this course at meeting its many intertwined goals, based on both quantitative and qualitative data collected from students in two recent course offerings.
Anopheles species composition explains differences in Plasmodium transmission in La Guajira, northern Colombia

Malaria in La Guajira, the most northern state of Colombia, shows two different epidemiological patterns. Malaria is endemic in the municipality of Dibulla whereas in Riohacha it is characterised by sporadic outbreaks. This study aimed to establish whether differences in transmission patterns could be attributed to different vector species. The most abundant adult female species were Anopheles aquasalis, exclusive to Riohacha, and Anopheles darlingi, restricted to Dibulla. Anopheles mosquitoes were identified using morphology and the molecular markers internal transcribed spacer 2 and cytochrome c oxidase I. All specimens (n = 1,393) were tested by ELISA to determine natural infection rates with Plasmodium falciparum and Plasmodium vivax. An. darlingi was positive for P. vivax 210, with an infection rate of 0.355% and an entomological inoculation rate of 15.87 infective bites/person/year. Anopheles albimanus larvae were the most common species in Riohacha, found in temporary swamps; in contrast, in Dibulla An. darlingi were detected mainly in permanent streams. Distinctive species composition and larval habitats in each municipality may explain the differences in Plasmodium transmission and suggest different local strategies should be used for vector control.
2005-38 Generalized Steady-state Analysis of Multiphase Interleaved Boost Converter with Coupled

The generalised steady-state analysis of the multi-phase interleaved boost converter with coupled inductors operated in continuous inductor current mode is addressed. The analytical expressions for efficiency, inductor and input currents, and output voltage are derived from the transformed average state–space model. Generalised expressions for the input and inductor current ripples and the output voltage ripple are also derived for various inductor couplings and the characteristics are analysed according to the inductor couplings. The steady-state performance is verified experimentally.
Fatal immune haemolysis associated with nomifensine.

Delayed gastric emptying was shown in patients with symptomatic uraemia compared with asymptomatic controls. This abnormality may be confined to patients with uraemia not undergoing dialysis, and our observation ofnormal gastric emptying in three of four uraemic patients receiving dialysis confirms a previous report, which found no disturbance in gastric motility in 10 patients with renal failure undergoing haemodialysis. Possible explanations for the delay in gastric emptying include electrolyte disturbance, uraemic toxins, raised plasma concentrations of gastrointestinal hormones, and dysfunction of the autonomic nervous system. The influence of symptoms such as nausea on gastric function must also be considered as it is not clear whether delayed gastric emptying causes these symptoms or is a consequence of them. Our finding may aid the interpretation of pharmacokinetic data in patients with uraemia and it provides a rationale for using drugs that promote gastric emptying in uraemic patients with nausea and vomiting.4 5
Place-Based Curriculum and Instruction: Outdoor and Environmental Education Approaches. ERIC Digest.

Place-Based Curriculum and Instruction: Outdoor and Environmental Education Approaches. ERIC Digest. 2 OUTDOOR EDUCATION, ENVIRONMENTAL EDUCATION AND PLACE-BASED EDUCATION:. 2 WHAT ARE THE ESSENTIAL CHARACTERISTICS OF PLACE-BASED EDUCATION? 3 WHY IS PLACE-BASED EDUCATION IMPORTANT? 4 WHAT ARE SOME SOURCES OF PLACE-BASED CURRICULUM? 4 CONCLUSION AND RECOMMENDATIONS FOR FUTURE DIRECTIONS. 6 REFERENCES. 7
Non-BPS Dp-brane in the background of NS5-branes on transverse R3 × S1

This paper is devoted to the study of non-BPS Dp-branes in the presence of NS5-branes on the transverse R3 × S1. We will formulate the tachyon effective action in this background and then we will discuss its properties. Then we will study the solutions of the equations of motion that describe lower dimensional BPS and non-BPS D-branes.
Pengaruh Model Pembelajaran Project Based Learning Terhadap Kemampuan Pemahaman Konsep Mahasiswa Mata Kuliah Kapita Selekta Matematika Pendidikan Dasar FKIP UMSU

Kemampuan Pemahaman Konsep mahasiswa tidak hanya dipengaruhi oleh umpan balik hasil ujian tetapi banyak faktor yang lain, misalnya : metode dan model pembelajaran yang digunakan. Adapun tujuan penelitian ini; (1) Bagaimana pengaruh model pembelajaran Project Based Learning terhadap Kemampuan Pemahaman Konsep mahasiswa mata kuliah kapita selekta matematika pendidikan dasar? (2) Berapa besar pengaruh model pembelajaran Project Based Learning terhadap Kemampuan Pemahaman Konsep mahasiswa mata kulliah kapita selekta matematika pendidikan dasar? Penelitian ini merupakan penelitian eksperimen semu. Adapun teknik analisis data dilakukan dari tahapan uji deskripsi data, selanjutnya uji prasyarat yaitu uji normalitas dan kelinieritasan, kemudian uji korelasi parsial. Langkah-langkah dalam penelitian adalah sebagai berikut : (1) Mahasiswa melakukan perencanaan; (2) Mendesain; (3) Melakukan presentasi awal; (4) Melakukan penelitian (riset mini),(5) Membuat laporan penelitian, (6) Melakukan presentasi akhir/evaluasi. Hasil penelitian ini memperoleh perhitungan sebesar 0.797 itu berarti merupakan pengaruh model pembelajaran project based learning berpengaruh sebesar 0,797 terhadap kemampuan pemahaman konsep mahasiswa prodi pendidikan matemtika FKIP UMSU.
Influence of sex hormones on the periodontium.

OBJECTIVES Sex hormones have long been considered to play an influential role on periodontal tissues, bone turnover rate, wound healing and periodontal disease progression. The objectives of this review article are to (1) address the link between sex hormones and the periodontium, (2) analyse how these hormones influence the periodontium at different life times and (3) discuss the effects of hormone supplements/replacement on the periodontium. MATERIALS AND METHODS Two autonomous searches were performed in English language utilizing Medline, Premedline and Pubmed as the online databases. Publications up to 2002 were selected and further reviewed. In addition, a manual search was also performed including specific related journals and books. RESULTS It is certain that sexual hormones play a key role in periodontal disease progression and wound healing. More specifically, these effects seem to differentiate by gender as well as lifetime period. In addition, the influence of sex hormones can be minimized with good plaque control and with hormone replacement. CONCLUSION Despite profound research linking periodontal condition with sex hormones kinetics, more definitive molecular mechanisms and therapy still remain to be determined.
Neuron Report Pathological Tau Disrupts Ongoing Network Activity

Highlights d Pathological tau disrupts the activity of single cells and neocortical networks d Pathological tau alters neocortical neuronal oscillatory patterns d Pathological tau affects firing patterns of neocortical pyramidal cells In Brief Menkes-Caspi et al. show that the activity of cortical neurons is reduced in tau-transgenic mice, including in neurons without detectable pathological tau. The pathological effects on a group of neurons are amplified and propagated through the entire cortical network. SUMMARY Pathological tau leads to dementia and neurodegen-eration in tauopathies, including Alzheimer's disease. It has been shown to disrupt cellular and synaptic functions, yet its effects on the function of the intact neocortical network remain unknown. Using in vivo intracellular and extracellular recordings, we measured ongoing activity of neocortical pyrami-dal cells during various arousal states in the rTg4510 mouse model of tauopathy, prior to significant cell death, when only a fraction of the neurons show pathological tau. In transgenic mice, membrane potential oscillations are slower during slow-wave sleep and under anesthesia. Intracellular recordings revealed that these changes are due to longer Down states and state transitions of membrane potentials. Firing rates of transgenic neurons are reduced, and firing patterns within Up states are altered, with longer latencies and inter-spike intervals. By changing the activity patterns of a subpopu-lation of affected neurons, pathological tau reduces the activity of the neocortical network.
DISTANCE SCALE ZERO POINTS FROM GALACTIC RR LYRAE STAR PARALLAXES

We present new absolute trigonometric parallaxes and proper motions for seven Population II variable stars—five RR Lyr variables: RZ Cep, XZ Cyg, SU Dra, RR Lyr, and UV Oct; and two type 2 Cepheids: VY Pyx and κ Pav. We obtained these results with astrometric data from Fine Guidance Sensors, white-light interferometers on Hubble Space Telescope. We find absolute parallaxes in milliseconds of arc: RZ Cep, 2.12 ± 0.16 mas; XZ Cyg, 1.67 ± 0.17 mas; SU Dra, 1.42 ± 0.16 mas; RR Lyr, 3.77 ± 0.13 mas; UV Oct, 1.71 ± 0.10 mas; VY Pyx, 6.44 ± 0.23 mas; and κ Pav, 5.57 ± 0.28 mas; an average σπ/π = 5.4%. With these parallaxes, we compute absolute magnitudes in V and K bandpasses corrected for interstellar extinction and Lutz–Kelker–Hanson bias. Using these RR Lyrae variable star absolute magnitudes, we then derive zero points for MV–[Fe/H] and MK–[Fe/H]–log P relations. The technique of reduced parallaxes corroborates these results. We employ our new results to determine distances and ages of several Galactic globular clusters and the distance of the Large Magellanic Cloud. The latter is close to that previously derived from Classical Cepheids uncorrected for any metallicity effect, indicating that any such effect is small. We also discuss the somewhat puzzling results obtained for our two type 2 Cepheids.
Divergent Hydraulic Safety Strategies in Three Co-occurring Anacardiaceae Tree Species in a Chinese Savanna

Vulnerability segmentation, the condition under which plant leaves are more vulnerable to drought-induced cavitation than stems, may act as a “safety valve” to protect stems from hydraulic failure. Evergreen, winter-deciduous, and drought-deciduous tree species co-occur in tropical savannas, but there have been no direct studies on the role of vulnerability segmentation and stomatal regulation in maintaining hydraulic safety in trees with these three leaf phenologies. To this end, we selected three Anacardiaceae tree species co-occurring in a Chinese savanna, evergreen Pistacia weinmanniifolia, drought-deciduous Terminthia paniculata, and winter-deciduous Lannea coromandelica, to study inter-species differentiation in leaf and stem hydraulic safety. We found that the two deciduous species had significantly higher sapwood-specific hydraulic conductivity and leaf-specific hydraulic conductance than the evergreen species. Moreover, two deciduous species were more vulnerable to stem cavitation than the evergreen species, although both drought-deciduous species and evergreen species had drought-resistance leaves. The evergreen species maintained a wide hydraulic safety margin (HSM) in stems and leaves; which was achieved by embolism resistance of both stems and leaves and isohydric stomatal control. Both deciduous species had limited HSMs in stems and leaves, being isohydric in the winter-deciduous species and anisohydric in drought-deciduous species. The difference in water potential at 50% loss of hydraulic conductivity between the leaves and the terminal stems (P50leaf−stem) was positive in P. weinmanniifolia and L. coromandelica, whereas, T. paniculata exhibited a lack of vulnerability segmentation. In addition, differences in hydraulic architecture were found to be closely related to other structural traits, i.e., leaf mass per area, wood density, and sapwood anatomy. Overall, the winter-deciduous species exhibits a drought-avoidance strategy that maintains the hydraulic safety of the more carbon-costly stems by sacrificing cheaper and more vulnerable leaves, while the evergreen species exhibits a hydraulic strategy of drought tolerance with strong stomatal regulation. In contrast, the drought-deciduous species lacks vulnerability segmentation and sheds leaves at the expense of top shoots during peak drought. This study demonstrates that even sympatric tree species that differ in leaf phenology can exhibit divergent adaptive hydraulic safety strategies.
ACCD: an algorithm for comprehension-driven clustering

The software clustering literature contains many different approaches that attempt to automatically decompose software systems. These approaches commonly utilize criteria or measures based on principles such as high cohesion and low coupling, information hiding etc. We present an algorithm that subscribes to a philosophy targeted towards program comprehension and based on subsystem patterns. We discuss the algorithm's implementation and describe experiments that demonstrate its usefulness.
Overconfidence and Delegated Portfolio Management

Following extensive empirical evidence about market anomalies and overconfidence, the analysis of financial markets with agents overconfident about the precision of their private information has received a lot of attention.However, all these models consider agents trading for their own account.In this article, we analyse a standard delegated portfolio management problem between a financial institution and a money manager who may be of two types: rational or overconfident.We consider several situations.In each case, we derive the optimal contract and results on the performance of financial institution hiring overconfident managers relative to institutions hiring rational agents, and results on the price impact of overconfidence.
A Note on Quantum Geometric Langlands Duality, Gauge Theory, and Quantization of the Moduli Space of Flat Connections

Montonen-Olive duality implies that the categories of A-branes on the moduli spaces of Higgs bundles on a Riemann surface C for a pair of Langlands-dual groups are equivalent. We reformulate this as a statement about categories of B-branes on the quantized moduli spaces of flat connections for these groups. We show that it implies the statement of the Quantum Geometric Langlands duality with a purely imaginary ``quantum parameter'' which is proportional to the inverse of the Planck constant of the gauge theory. The ramified version of the story is also considered.
New Economic Geography and Reunified Germany at Twenty: A Fruitful Match?

Abstract We qualitatively match new economic geography (NEG) to stylized facts on German economic integration after 1989. We find that NEG may explain German integration reasonably well. Germany may currently be close to the peak of the bell curve, which describes the long-run relationship between integration and agglomeration in Germany. As a consequence, further economic integration between the two parts of Germany may eventually foster redispersion of economic activity toward East Germany. We also identify limitations of NEG for explaining German integration, most notably the analytical complexity of multi-region models and its neglect of knowledge spillovers and labour pooling. RÉSUMÉ Nous établissons une correspondance qualitative entre la nouvelle géographie économique (NEG) et des faits stylisés sur l'intégration économique allemande après 1989. Nous découvrons que la NEG permet d'expliquer raisonnablement bien l'intégration allemande. En fait, l'Allemagne est sans doute proche du sommet de la courbe en cloche, décrivant les rapports de longue durée entre l'intégration et l'agglomération en Allemagne. Donc, la poursuite de l'intégration économique entre les deux parties de l'Allemagne pourra favoriser une re-dispersion de l'activité économique envers l'Allemagne de l'Est. Néantmoins, nous identifions des limitations de la MEG pour expliquer l'intégration allemande, notamment la complexité analytique des modèles multirégionaux et la négligeance des retombées des connaissances (knowledge spillovers) et le groupement de la main-d'œuvre. Extracto Emparejamos cualitativamente la Nueva Geografía Económica (NEG) con hechos estilizados de la integración económica alemana después de 1989. Descubrimos que la NEG puede explicar la integración alemana razonablemente bien. Actualmente, Alemania podría estar cerca de la cumbre de la curva de campana que describe la asociación a largo plazo entre integración y aglomeración en Alemania. En consecuencia, una mayor integración económica entre las dos partes de Alemania podría fomentar últimamente la re-dispersión de actividad económica hacia la Alemania del Este. Además identificamos limitaciones de la NEG para explicar la integración alemana, consistiendo principalmente en la complejidad analítica de los modelos multirregionales y en su preterición de los desbordamientos de conocimiento (knowledge spillovers) y de la concentración de mano de obra cualificada (labour pooling). 摘要:我们将新经济地理(NEG)和1989年德国经济统一后的典型事实进行定性比较。 我们发现NEG可以很好地解释德国统一。 德国现在非常接近钟形曲线的峰值, 意味着德国经济会长期呈现融合和聚集并存。 因此, 东西德之间进一步的经济融合将最终促进经济活动流向东德。 我们还找出了用NEG解释德国统一的局限性，尤其是多区域模型分析的复杂性以及对人才流失和劳动力储备的忽略。
1H-NMR-Based Metabolomic Study for Identifying Serum Profiles Associated with the Response to Etanercept in Patients with Rheumatoid Arthritis

Objective A considerable proportion of patients with rheumatoid arthritis (RA) do not have a satisfactory response to biological therapies. We investigated the use of metabolomics approach to identify biomarkers able to anticipate the response to biologics in RA patients. Methods Due to gender differences in metabolomic profiling, the analysis was restricted to female patients starting etanercept as the first biological treatment and having a minimum of six months’ follow-up. Each patient was evaluated by the same rheumatologist before and after six months of treatment. At this time, the clinical response (good, moderate, none) was determined according to the EUropean League Against Rheumatism (EULAR) criteria, based on both erythrocyte sedimentation rate (EULAR-ESR) and C-reactive protein (EULAR-CRP). Sera collected prior and after six months of etanercept were analyzed by 1H-nuclear magnetic resonance (NMR) spectroscopy in combination with multivariate data analysis. Results Twenty-seven patients were enrolled: 18 had a good/moderate response and 9 were non responders according to both EULAR-ESR and EULAR-CRP after six months of etanercept. Metabolomic analysis at baseline was able to discriminate good, moderate, and non-responders with a very good predictivity (Q2 = 0.68) and an excellent sensitivity, specificity, and accuracy (100%). In good responders, we found an increase in isoleucine, leucine, valine, alanine, glutamine, tyrosine, and glucose levels and a decrease in 3-hydroxybutyrate levels after six months of treatment with etanercept with respect to baseline. Conclusion Our study confirms the potential of metabolomic analysis to predict the response to biological agents. Changes in metabolic profiles during treatment may help elucidate their mechanism of action.
The Impact of Astrocytic Gap Junctional Coupling on Potassium Buffering in the Hippocampus

Astrocytic gap junctions have been suggested to contribute to spatial buffering of potassium in the brain. Direct evidence has been difficult to gather because of the lack of astrocyte-specific gap junction blockers. We obtained mice with coupling-deficient astrocytes by crossing conditional connexin43-deficient mice with connexin30−/− mice. Similar to wild-type astrocytes, genetically uncoupled hippocampal astrocytes displayed negative resting membrane potentials, time- and voltage-independent whole-cell currents, and typical astrocyte morphologies. Astrocyte densities were also unchanged. Using potassium-selective microelectrodes, we assessed changes in potassium buffering in hippocampal slices of mice with coupling-deficient astrocytes. We demonstrate that astrocytic gap junctions accelerate potassium clearance, limit potassium accumulation during synchronized neuronal firing, and aid in radial potassium relocation in the stratum lacunosum moleculare. Furthermore, slices of mice with coupling-deficient astrocytes displayed a reduced threshold for the generation of epileptiform events. However, it was evident that radial relocation of potassium in the stratum radiatum was not dependent on gap junctional coupling. We suggest that the perpendicular array of individual astrocytes in the stratum radiatum makes these cells ideally suited for spatial buffering of potassium released by pyramidal cells, independent of gap junctions. In general, a surprisingly large capacity for K+ clearance was conserved in mice with coupling-deficient astrocytes, indicating that gap junction-dependent processes only partially account for K+ buffering in the hippocampus.
A new non-naked species of Ptychostomella (Gastrotricha) from Brazil

Abstract A new species of marine Gastrotricha from Brazil is described and discussed. Ptychostomella lamelliphora sp. n. is one of the several new taxa that were found during an extensive survey of the gastrotrich fauna carried out in 2002 and 2003 along the coastline of the State of São Paulo. The new species is unique in that it possesses cuticular ornamentations in the form of plate-like structures (scales) along the lateral borders of the body and two massive clusters of densely packed adhesive tubes on the ventral surface, near the ano-genital opening. Both these features appear to be adaptations to challenge the high energy waters that characterize the species’ microhabitat: the coarse sublittoral sand in the channel between the mainland and the largest island in the State, Ihlabela. Additionally, a key to the described Ptychostomella species of the world is provided.
Towards Integrated Verification of Timed Transition Models

This paper describes an attempt to combine theorem proving and model-checking to formally verify real-time systems in a discrete time setting. The Timed Automata Modeling Environment (TAME) has been modified to provide a formal model for Time Transition Models (TTMs) in the PVS proof checker. Strong and weak state-event observation equivalences are formalized in PVS for state-event labeled transition systems (SELTS), the underlying semantic model of TTMs. The state-event equivalences form the basis of truth value preserving abstractions for a real-time temporal logic. When appropriate restrictions are placed upon the TTMs, their PVS models can be easily translated into input for the SAL model-checker. A simple real-time control system is specified and verified using these theories. While these preliminary results indicate that the combination of PVS and SAL could provide a useful environment to perform equivalence verification, model-checking and compositional model reduction of real-time systems, the current implementation in the general purpose SAL model-checker lags well behind state of the art real-time model-checkers.