Miracle-dz/UniFAR-FTUs huggingface dataset:
Fasting Plasma Glucose, Self-Appraised Diet Quality and Depressive Symptoms: A US-Representative Cross-Sectional Study

Depression and type 2 diabetes (T2D) contribute significantly to global burden of disease and often co-occur. Underpinning type 2 diabetes is poor glycaemic control and glucose is also an obligatory substrate for brain metabolism, with potential implications for cognition, motivation and mood. This research aimed to examine the relationships between fasting plasma glucose and depressive symptoms in a large, population representative sample of US adults, controlling for other demographic and lifestyle behavioural risk factors. Using the 2013–2014 National Health and Nutrition Examination Survey (NHANES) data, this study first investigated the relationship between fasting plasma glucose and mental disorders at a population-level, accounting for demographic, health behavioural and weight-related factors known to co-occur with both type 2 diabetes and mental disorders. Depressive symptoms were derived from the 9-item Patient Health Questionnaire. Fasting plasma glucose was obtained through medical examination and demographic (age, household income, sex) and health characteristics (perceived diet quality, daily time sedentary) were self-reported. Body mass index was calculated from objectively measured height and weight. In the univariate model, higher fasting plasma glucose was associated with greater depressive symptoms among females (b = 0.24, 95% CI = 0.05, 0.43, p < 0.05), but not males. In the final fully adjusted model, the relationship between fasting plasma glucose and depressive symptoms was non-significant for both males and females. Of all independent variables, self-appraised diet quality was strongly and significantly associated with depressive symptoms and this remained significant when individuals with diabetes were excluded. Although diet quality was self-reported based on individuals’ perceptions, these findings are consistent with a role for poor diet in the relationship between fasting plasma glucose and depressive symptoms.
Brain Indices of Music Processing: Nonmusicians are Musical

Only little systematic research has examined event-related brain potentials (ERPs) elicited by the cognitive processing of music. The present study investigated how music processing is influenced by a preceding musical context, affected by the task relevance of unexpected chords, and influenced by the degree and the probability of violation. Four experiments were conducted in which nonmusicians listened to chord sequences, which infrequently contained a chord violating the sound expectancy of listeners. Integration of in-key chords into the musical context was reflected as a late negative-frontal deflection in the ERPs. This negative deflection declined towards the end of a chord sequence, reflecting normal buildup of musical context. Brain waves elicited by chords with unexpected notes revealed two ERP effects: an early right-hemispheric preponderant-anterior negativity, which was taken to reflect the violation of sound expectancy; and a late bilateral-frontal negativity. The late negativity was larger compared to in-key chords and taken to reflect the higher degree of integration needed for unexpected chords. The early right-anterior negativity (ERAN) was unaffected by the task relevance of unexpected chords. The amplitudes of both early and late negativities were found to be sensitive to the degree of musical expectancy induced by the preceding harmonic context, and to the probability for deviant acoustic events. The employed experimental design opens a new field for the investigation of music processing. Results strengthen the hypothesis of an implicit musical ability of the human brain.
Tokenizing, POS Tagging, Lemmatizing and Parsing UD 2.0 with UDPipe

Many natural language processing tasks, including the most advanced ones, routinely start by several basic processing steps – tokenization and segmentation, most likely also POS tagging and lemmatization, and commonly parsing as well. A multilingual pipeline performing these steps can be trained using the Universal Dependencies project, which contains annotations of the described tasks for 50 languages in the latest release UD 2.0. We present an update to UDPipe, a simple-to-use pipeline processing CoNLL-U version 2.0 files, which performs these tasks for multiple languages without requiring additional external data. We provide models for all 50 languages of UD 2.0, and furthermore, the pipeline can be trained easily using data in CoNLL-U format. UDPipe is a standalone application in C++, with bindings available for Python, Java, C# and Perl. In the CoNLL 2017 Shared Task: Multilingual Parsing from Raw Text to Universal Dependencies, UDPipe was the eight best system, while achieving low running times and moderately sized models.
Role of the L1 in FL classrooms: learner and teacher beliefs, attitudes, and practices

The role of first language (L1) has been controversial in foreign language (FL) learning and teaching. This study examines the relationship between L1 use and gender and level of education of EFL teachers as well as gender and EFL proficiency level of learners in an Afghan university setting. It also investigates the relationship between FL use and learner anxiety by learner gender and EFL proficiency level. The study hypothesized that female FL teachers use the L1 more than male teachers in FL classrooms. Second, low FL proficiency learners consider L1 use as necessary in FL classrooms. Third, low FL proficiency students experience more anxiety with the exclusive use of FL than higher level learners. Fourth, female learners experience more anxiety than male students with the exclusive use of FL by learners and teachers. Twenty EFL teachers participated in the study by completing a 19-item questionnaire and sixty EFL learners by completing a 27-item questionnaire about their views towards L1/FL use and learner anxiety. The data, analyzed through SPSS software, included calculating frequencies and percentages, computing correlations, and conducting independent-samples t-tests to compare the mean difference between the variables. The first hypothesis was not supported as male teachers reported using the L1 more than female teachers. The study also revealed that male teachers with BA and MA degrees used the L1 more than female teachers with BA degrees. In contrast, female teachers with MA degrees used the L1 more than male teachers with BA and MA degrees and also more than female teachers with BA degrees. The results supported hypothesis two. More elementary learners considered the use of L1 as necessary than intermediate and advanced students. The findings also supported hypotheses three and four. Elementary learners as well as female students experienced more anxiety with the exclusive use of FL than intermediate and advanced level students and male learners. The principal conclusion indicated a significant positive correlation between the exclusive use of FL and learner anxiety. iv Table of
Acute kidney injury in pediatric patients: experience of a single center during an 11-year period.

UNLABELLED The aim of our study was to determine the causes of acute kidney injury (AKI) in children, to compare outcomes between two periods--1998-2003 and 2004-2008--and to evaluate the influence of new methods of renal replacement therapy on mortality. MATERIAL AND METHODS A retrospective analysis of medical record data of all children treated for AKI at the Clinic of Children Diseases, Hospital of Kaunas University of Medicine, during the period of 1998-2008 was made. Both periods were compared regarding various variables. RESULTS Of the 179 children with AKI, 75 (41.9%) were treated during 1998-2003 and 104 (58.1%) during 2004-2008. Primary glomerular disease and sepsis were the leading causes of AKI in both the periods. AKI without involvement of other organs was diagnosed for 106 (59.2%) children: for 42 (56.0%) children in the first period and 64 (61.5%) in the second. A total of 124 (69.3%) children were treated in a pediatric intensive care unit. Multiple organ dysfunction syndrome with AKI was diagnosed for 33 (44%) patients in the first period and for 40 (38.5%) in the second. A significant decrease in mortality among patients with multiple organ dysfunction syndrome during the second period was observed (78.8% vs. 37.5%). CONCLUSIONS More than half of patients had secondary acute kidney injury of nonrenal origin. More than two-thirds (69.3%) of patients with AKI were treated in the pediatric intensive care unit. Multiple organ dysfunction syndrome was diagnosed for 40.8% of children with AKI. Renal replacement therapy was indicated for one-third of patients with AKI. A 2.5-fold decrease in mortality was observed in the second period as compared to the first one.
Resembling breast milk: influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota

Infant microbiota is influenced by numerous factors, such as delivery mode, environment, prematurity and diet (breast milk or formula). In addition to its nutritional value, breast milk contains bioactive substances that drive microbial colonisation and support immune system development, which are usually not present in infant formulas. Among these substances, polyamines have been described to be essential for intestinal and immune functions in newborns. However, their effect on the establishment of microbiota remains unclear. Therefore, the aim of the present study was to ascertain whether an infant formula supplemented with polyamines has an impact on microbial colonisation by modifying it to resemble that in breast-fed neonatal BALB/c mice. In a 4 d intervention, a total of sixty pups (14 d old) were randomly assigned to the following groups: (1) breast-fed group; (2) non-enriched infant formula-fed group; (3) three different groups fed an infant formula enriched with increasing concentrations of polyamines (mixture of putrescine, spermidine and spermine), following the proportions found in human milk. Microbial composition in the contents of the oral cavity, stomach and small and large intestines was analysed by quantitative PCR targeted at fourteen bacterial genera and species. Significantly different (P< 0·05) microbial colonisation patterns were observed in the entire gastrointestinal tract of the breast-fed and formula-fed mice. In addition, our findings demonstrate that supplementation of polyamines regulates the amounts of total bacteria, Akkermansia muciniphila, Lactobacillus, Bifidobacterium, Bacteroides–Prevotella and Clostridium groups to levels found in the breast-fed group. Such an effect requires further investigation in human infants, as supplementation of an infant formula with polyamines might contribute to healthy gastrointestinal tract development.
General Capacity for Deterministic Dissemination in Wireless Ad Hoc Networks

In this paper, we study capacity scaling laws of the deterministic dissemination (DD) in random wireless networks under the generalized physical model (GphyM). This is truly not a new topic. Our motivation to readdress this issue is two-fold: Firstly, we aim to propose a more general result to unify the network capacity for general homogeneous random models by investigating the impacts of different parameters of the system on the network capacity. Secondly, we target to close the open gaps between the upper and the lower bounds on the network capacity in the literature. The generality of this work lies in three aspects: (1) We study the homogeneous random network of a general node density $\lambda \in [1,n]$, rather than either random dense network (RDN, $\lambda=n$) or random extended network (REN, $\lambda=1$) as in the literature. (2) We address the general deterministic dissemination sessions, \ie, the general multicast sessions, which unify the capacities for unicast and broadcast sessions by setting the number of destinations for each session as a general value $n_d\in[1,n]$. (3) We allow the number of sessions to change in the range $n_s\in(1,n]$, instead of assuming that $n_s=\Theta(n)$ as in the literature. We derive the general upper bounds on the capacity for the arbitrary case of $(\lambda, n_d, n_s)$ by introducing the Poisson Boolean model of continuum percolation, and prove that they are tight according to the existing general lower bounds constructed in the literature.
Future of High-Density Lipoprotein Infusion Therapies: Potential for Clinical Management of Vascular Disease

The field of high-density lipoprotein (HDL) therapeutics is broadly aimed at combating the significant residual cardiovascular risk remaining after effective low-density lipoprotein (LDL) cholesterol reduction.1 After the recent failure of 3 orally active HDL-raising agents in prospective intervention trials, including 2 in the cholesteryl ester transfer protein (CETP) inhibitor class2,3 and niacin,4,5 the goals of HDL therapy are currently undergoing reassessment. Key opinion leaders are advocating a shift in the target of HDL therapy from elevation in circulating HDL cholesterol levels to enhancement of the functional properties of HDL, especially HDL-mediated reverse cholesterol transport and cellular cholesterol efflux.6,7 These events have focused the spotlight on HDL infusion therapies that transiently increase HDL particle number and enhance efflux capacity for cellular cholesterol; other defective features of HDL functionality may potentially be normalized.8 However, evaluation of HDL infusion therapies has been limited to date to small surrogate end-point trials; indeed, large phase 3 outcome trials to test the efficacy of these agents in reducing definitive morbidity and mortality end points are eagerly awaited. If proven effective, HDL infusion agents would have potential application across a wide range of vascular diseases but would be particularly amenable to delivery in the context of acute coronary syndromes. Coronary artery disease morbidity and mortality relate largely to either physical disruption or endothelial erosion of the fibrous cap of atherosclerotic plaques in the coronary arteries, triggering luminal or intraplaque thrombus formation.9 An acute or unstable coronary syndrome (sudden death, nonfatal myocardial infarction, or unstable angina) results, the nature of which depends in large part on the degree of vessel occlusion. Plaques at greatest risk for rupture are characterized by a marked abundance of both extracellular and intracellular lipid (cholesterol); immunoinflammatory cells, including monocyte-macrophages and T …
Mycoplasma bovis pneumonia in cattle

Abstract Mycoplasma bovis is an important and emerging cause of respiratory disease and arthritis in feedlot cattle and young dairy and veal calves, and has a variety of other disease manifestations in cattle. M. bovis is certainly capable of causing acute respiratory disease in cattle, yet the attributable fraction has been difficult to estimate. In contrast, M. bovis is more accepted as a cause of chronic bronchopneumonia with caseous and perhaps coagulative necrosis, characterized by persistent infection that seems poorly responsive to many antibiotics. An understanding of the disease has been recently advanced by comparisons of natural and experimentally induced disease, development of molecular diagnostic tools, and understanding some aspects of virulence, yet uncertainties regarding protective immunity, the importance of genotypic diversity, mechanisms of virulence, and the role of co-pathogens have restricted our understanding of pathogenesis and our ability to effectively control the disease. This review critically considers the relationship between M. bovis infection and the various manifestations of the bovine respiratory disease complex, and addresses the pathogenesis, clinical and pathologic sequelae, laboratory diagnosis and control of disease resulting from M. bovis infection in the bovine respiratory tract.
Climate and the Collapse of Maya Civilization

In the anoxic Cariaco Basin of the southern Caribbean, the bulk titanium content of undisturbed sediment reflects variations in riverine input and the hydrological cycle over northern tropical South America. A seasonally resolved record of titanium shows that the collapse of Maya civilization in the Terminal Classic Period occurred during an extended regional dry period, punctuated by more intense multiyear droughts centered at approximately 810, 860, and 910 A.D. These new data suggest that a century-scale decline in rainfall put a general strain on resources in the region, which was then exacerbated by abrupt drought events, contributing to the social stresses that led to the Maya demise.
Diagnostic utility of mammaglobin and GCDFP‐15 in the identification of metastatic breast carcinoma in fluid specimens

Morphologic differentiation of breast carcinoma from nonmammary malignancies in fluid specimens can be a diagnostic challenge. Immunocytochemistry is often employed in the differential diagnosis. In this study, we evaluated the expression of mammoglobin (MGB1) in body‐cavity fluid specimens and compared its efficacy as a marker for metastatic breast carcinomas with that of gross cystic disease fluid protein‐15 (GCDFP‐15). Cell blocks from 40 fluid specimens were immunostained with monoclonal antibodies against MGB1 and GCDFP‐15. They included 15 breast carcinomas and 25 nonmammary carcinomas (10 lungs, 10 ovaries, 3 gastrointestinal tracts, 1 kidney, and 1 urinary bladder). Positivity was defined as the presence of cytoplasmic staining in 10% or more carcinoma cells. Thirteen (87%) and seven (47%) breast carcinomas showed positive staining with MGB1 and GCDFP‐15, respectively. Three (12%) nonmammary carcinomas (2 ovarian and 1 colonic) showed positive MGB1 staining; one (3%) nonmammary carcinoma demonstrated positive GCDFP‐15 staining. The differences of MGB1 and GCDFP‐15 staining between breast and nonmammary carcinomas were statistically significant (P < 0.05). Both MGB1 and GCDFP‐15 are specific markers for metastatic breast carcinomas in cell block fluid specimens (88 vs. 96%). However, MGB1 is more sensitive than GCDFP‐15 as a marker for metastatic breast carcinoma (87 vs. 46%). Diagn. Cytopathol. 2009. © 2009 Wiley‐Liss, Inc.
Verbal ability, social stress, and anxiety in children with Autistic Disorder

The aims of this study were to evaluate the physiological stress and anxiety responses in children with autism following completion of a standardized, social-evaluative stressor (Trier Social Stress Test-Child version), document the relationship between verbal ability, stress, and anxiety, and determine the association between stress and anxiety in children with autism and typical development. Results demonstrated the Trier Social Stress Test-Child version to be a benign stressor for children with autism. Lower verbal ability in children with autism did not predict salivary cortisol or anxiety responses. There was a lack of association between stress andanxiety for both groups, highlighting the importance of considering these terms as separate constructs. Clinical implications and the limited utility of the Trier Social Stress Test–Child version in evaluating psychosocial stress in autism are discussed.
AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer

Background Dermatologic toxicities, especially akne-like skin rash, are the most common side-effects associated with anti-epidermal growth factor receptor (EGFR) therapy. Preemptive treatment with oral tetracyclines is recommended as a standard. Topical prophylactic options have thus far not been compared to tetracyclines. In the current study, we sought to establish an alternative topical treatment. Patients and methods In this multicentre, randomized, open-label phase II study patients with (K)Ras-wildtype colorectal cancer receiving panitumumab were randomized (1:1) to receive either doxycycline 100 mg b.i. d. (standard arm) or erythromycin ointment 2% followed by doxycycline in case of insufficient activity. The primary endpoint was the percentage of patients developing no skin toxicity ≥ grade 2 at any time during the first 8 weeks of panitumumab treatment. Skin toxicity was assessed using the NCI CTCAE v 4.0. Secondary endpoints comprised the assessment of skin toxicity using a more thorough grading system (WoMo score), evaluation of skin-related (DLQI) and global quality of life (EORTC QLQ C30). Results In total, 88 patients were included in this trial. 69% of the patients in the erythromycin arm suffered from skin toxicity of grade ≥ 2 versus 63% in the standard arm (P = n.s.). However, as per WoMo score significantly more patients in the erythromycin arm developed moderate or severe skin toxicity at earlier time points. Skin related and overall quality of life was comparable between both arms. Conclusions Based on this data erythromycin cannot be regarded as an alternative to doxycycline as prevention of EGFR-related skin toxicity.
Distinguishing quantum operations having few Kraus operators

Entanglement is sometimes helpful in distinguishing between quantum operations, as differences between quantum operations can become magnified when their inputs are entangled with auxiliary systems. Bounds on the dimension of the auxiliary system needed to optimally distinguish quantum operations are known in several situations. For instance, the dimension of the auxiliary space never needs to exceed the dimension of the input space [23, 14] of the operations for optimal distinguishability, while no auxiliary system whatsoever is needed to optimally distinguish unitary operations [2, 6]. Another bound, which follows from work of R. Timoney [24], is that optimal distinguishability is always possible when the dimension of the auxiliary system is twice the number of operators needed to express the difference between the quantum operations in Kraus form. This paper provides an alternate proof of this fact that is based on concepts and tools that are familiar to quantum information theorists.
Multiswarms, exclusion, and anti-convergence in dynamic environments

Many real-world problems are dynamic, requiring an optimization algorithm which is able to continuously track a changing optimum over time. In this paper, we explore new variants of particle swarm optimization (PSO) specifically designed to work well in dynamic environments. The main idea is to split the population of particles into a set of interacting swarms. These swarms interact locally by an exclusion parameter and globally through a new anti-convergence operator. In addition, each swarm maintains diversity either by using charged or quantum particles. This paper derives guidelines for setting the involved parameters and evaluates the multiswarm algorithms on a variety of instances of the multimodal dynamic moving peaks benchmark. Results are also compared with other PSO and evolutionary algorithm approaches from the literature, showing that the new multiswarm optimizer significantly outperforms previous approaches
SVR-parameters selection for image watermarking

An image digital watermarking technique using support vector regression (SVR) is proposed and researched in this paper. Firstly, the method of embedding and extracting watermarking from digital image is given. Then, the influence of SVR-learning parameters on the watermarking performance is analyzed, and the ideal value range of SVR-learning parameters for different images is given respectively. Finally, the results are validated with other images. Experimental results show that this technique can obtain good watermarking performance as well as good learning performance when RBF kernel is adopted with its width a from 8 to 10, balanceable parameter C from 0.8 to 1, insensitive parameter s from 0.008 to 0.01 respectively