Miracle-dz/UniFAR-FTUs huggingface dataset:
Determining the Optimum Power Load in Jump Squat Using the Mean Propulsive Velocity

The jump squat is one of the exercises most frequently used to improve lower body power production, which influences sports performance. However, the traditional determination of the specific workload at which power production is maximized (i.e., optimum power load) is time-consuming and requires one-repetition maximum tests. Therefore, the aim of this study was to verify whether elite athletes from different sports would produce maximum mean propulsive power values at a narrow range of mean propulsive velocities, resulting in similar jump heights. One hundred and nine elite athletes from several individual/team sport disciplines underwent repetitions at maximal velocity with progressive loads, starting at 40% of their body mass with increments of 10% to determine the individual optimum power zone. Results indicated that regardless of sport discipline, the athletes’ optimum mean propulsive power was achieved at a mean propulsive velocity close to 1.0 m.s−1 (1.01 ± 0.07 m.s−1) and at a jump height close to 20 cm (20.47 ± 1.42 cm). Data were narrowly scattered around these values. Therefore, jump squat optimum power load can be determined simply by means of mean propulsive velocity or jump height determination in training/testing settings, allowing it to be implemented quickly in strength/power training.
Bacterial resistance to antimicrobial agents: selected problems in France, 1996 to 1998.

Dr. Aubry-Damon is a microbiologist specializing in antimicrobial resistance at the National Institute for Public Health Surveillance, Saint-Maurice, France. The institute has recently carried out an exploratory study of a national program for surveillance of antimicrobial resistance in France. Dr. Aubry-Damon also collaborates closely with the French National Reference Center for Antibiotics. (No photo available)
Detection of interferon-gamma-inducible chemokines in human milk.

AIM To assess the immunological role of human milk by analysing the concentrations of interferon-gamma-inducible protein of 10 kda (IP-10) and monokine induced by interferon-gamma (MIG) in human milk from mothers of preterm and term infants. METHODS IP-10 and MIG levels of colostrum, early milk, mature milk and sera were measured by enzyme-linked immunosorbent assay (ELISA). IP-10 and MIG mRNA expression levels in cellular components of human milk were determined by RT-PCR. IP-10 and MIG protein expression in mammary gland tissues was analysed by immunohistochemistry. RESULTS Significant amounts of IP-10 and MIG were detected in human milk. The concentrations of IP-10 and MIG in colostrum and early milk were significantly higher than those of sera from healthy controls or lactating mothers. These chemokine concentrations in colostrum and early milk were significantly higher than those of mature milk. Premature delivery or pregnancy complications of mothers had no significant correlation with these chemokine concentrations in breast milk. There were significant correlations between MIG and interferon-gamma (IFN-gamma) or IP-10 levels (p < 0.001) in human milk. Expression of IP-10 and MIG genes and proteins in the milk cells as well as in mammary gland epithelial tissues was detected by RT-PCR and immunohistochemistry. CONCLUSION IP-10 and MIG in human milk, probably derived from milk cells and mammary gland epithelial cells, may contribute to the migration and activation of intestinal T lymphocytes to enhance mucosal immunity during the early neonatal period.
Soft‐tissue sarcomas of adults; study of pathological prognostic variables and definition of a histopathological grading system

The pathological features of 155 adult patients with soft‐tissue sarcomas were studied retrospectively, in an attempt to set up a grading system for these tumors. As the first step, seven histological criteria (tumor differentiation, cellularity, importance of nuclear atypia, presence of malignant giant cells, mitosis count, pattern of tumor necrosis and presence of vascular emboli) were evaluated in a monofactorial analysis. Five of these (tumor differentiation, cellularity, mitosis count, tumor necrosis, and vascular emboli) were correlated with the advent of metastases and with survival. A multivariate analysis, using a Cox model, selected a minimal set of three factors (tumor differentiation, mitosis count, and tumor necrosis) the combination of which was necessary and sufficient to retain all the prognostic information. A grading system was elaborated, which turned out to be correlated with the advent of metastasis and with patients' survival. A second multivariate analysis introducing clinical prognostic features showed that the histological grade was the most important prognostic factor for soft‐tissue sarcomas. Thus, this grading system appears to be highly interesting because of its prognostic value and the facility of its elaboration. However, its reproducibility should be tested.
Partial Replication in the Vesta Software Repository

The Vesta repository is a special-purpose replicated file system, developed as part of the Vesta software configuration management system. One of the major goals of Vesta is to make all software builds reproducible. To this end, the repository provides an append-only name space; new names can be inserted, but once a name exists, its meaning cannot change. More concretely, all files and some designated directories are immutable, while the remaining directories are appendable, allowing new names to be defined but not allowing existing names to be redefined. The data stored in a repository can be replicated, to support distributed software development. The append-only nature of the repository greatly simplifies the problem of maintaining consistency among replicas. Conceptually, all files and directories stored in all Vesta repositories are named in one single, global name space. Each repository stores some subtree of the complete name space. Replication is present when the subtrees stored by two different repositories overlap; that is, some of the same names and data occur in both. We call this concept partial replication, because each repository can choose to replicate all, part, or none of the data stored in any other repository. In this paper we outline the main features of the repository, give a definition for the consistency of partial replicas, describe how our replication tools maintain consistency, and briefly relate our experience in using the system for distributed software development between groups on opposite coasts of the United States.
Predicting girls' conduct disorder in adolescence from childhood trajectories of disruptive behaviors.

OBJECTIVE To examine girls' developmental trajectories of disruptive behaviors during the elementary school years and to predict conduct disorder symptoms and diagnosis in adolescence with trajectories of these behaviors. METHOD The sample was 820 girls from the province of Quebec followed over 10 years (1986-1996). A semiparametric mixture model was used to describe girls' developmental trajectories of teacher-rated disruptive behaviors between the ages of 6 and 12 years. The trajectories were used to predict conduct disorder symptoms and diagnosis when the girls were on average 15.7 years. RESULTS Four groups of girls following trajectories with distinct levels of disruptive behaviors were identified: a low, medium, medium-high, and high trajectory. Prediction with the trajectories indicated that girls on the medium, medium-high, and high trajectories reported a significantly higher number of conduct disorder symptoms in adolescence. However, only the girls on the medium-high and high trajectories were at significantly higher risk to meet DSM-III-R criteria for conduct disorder, compared with girls in the low group (odds ratio: 4.46). More than two thirds of the girls with conduct disorder were in the medium or higher-level trajectories. CONCLUSION The results suggest that there is an early-onset type of conduct disorder in girls.
Effect of Sowing Dateson Morphological Characteristics, Root Yield and Chemical Composition of the Root ofWithania Somnifera Grown in the Semi-Arid Regions of Andhra Pradesh, India

The present study was undertaken to study the effect of sowing date on morphology, yield and chemical composition of root of Withania somniferagrown in the semi arid regions of Andhra Pradesh, India. The experiment was carried out in the research farm of Central Institute ofand Aromatic Plants (CSIR-CIMAP) , Research Centre, Hyderabad, India during 2009-2011. The experimental material included two morphologically differen t ashwagandha cultivars i.e. Poshita [variety developed by CIMAP] and Nagore [local variety g
Levels Of Polychlorinated Biphenyls Residues In Warri River, Nigeria

Sum of individual PCBs congeners in surface water and sediment samples from Warri River system, a coastal river of Niger Delta, Nigeria were measured between March and June 2003. Specific individual PCBs analysis was by HPGC series 6890. Mean concentrations of ΣPCBs in surface water samples ranged from 0.35 μg l -l (Tori Creek) to 1.30 μg l -l (Crawford Creek). Sediment samples had higher levels ranging from 2.00 ng g -l (Tori Creek) to 7.00 ng g -l (Crawford Creek). Null hypothesis of normality was rejected at p>0.05 indicating significant difference between the matrices. Concentrations of PCB were compared with ecotoxicological benchmarks and regulatory guidelines to determine potential concern for effects on aquatic life and human health. Measured mean concentrations in surface water and sediments samples from Crawford creek station indicated concern for environmental and public health because of their exceedence of the US EPA PCB limit for drinking water (0.0005μgl -l ) and water quality criteria for chronic exposure (79pgl -l ) through drinking water and fish ingestion. KEY WORDS: PCBs, Water, Sediment, Hazard, Warri River. Global Journal of Environmental Sciences Vol.4(1) 2005: 65-71
Missed problems and missed opportunities for addicted doctors

Every few days another addicted doctor comes to light in Britain. A report from an alliance of health professional bodies, led by the British Medical Association and published last month,1 highlights the risk posed by such doctors to the general public and calls for better preventive education and awareness. It fails, however, to prioritise the need for improved treatment for addicted doctors.2 This need arises from the special problems facing addicted doctors compared with other addicts and their special treatment needs, which ordinary addiction services do not serve well. Doctors are at special risk of developing addiction problems,3 4 5 owing to the strain of medical practice, erosion of the taboo against injecting and opiates, and, particularly, access to supplies.6 Once addicted, they pose a particular risk to the general public, forcing consideration of whether they need urgent removal from their work. Ordinarily, many patients with drug or alcohol problems receive outpatient treatment while continuing to work, but the same level of disability may be incompatible with medical practice. In addition, since most doctors who become addicted to drugs …
Shock compression of diamond crystal

Two shock wave experiments employing inclined mirrors have been carried out to determine the Hugoniot elastic limit (HEL), final shock state at 191 and 217 GPa, and the post-shock state of diamond crystal, which is shock-compressed along the intermediate direction between the and crystallographic axes. The HEL wave has a velocity of 19.9 ± 0.3 mm/µsec and an amplitude of 63 ± 28 GPa. An alternate interpretation of the inclined wedge mirror streak record suggests a ramp precursor wave and then another HEL value. The maximum post-shock density achieved upon release from the ∼200 GPa shock state is ∼3.95 Mg/m³, which compares to the initial density 3.52 Mg/m³. This result suggests an elastic unloading effect or shock-induced transition to a denser (possibly metallic) phase.
A mathematical model quantifying GnRH-induced LH secretion from gonadotropes.

A mathematical model is developed to investigate the rate of release of luteinizing hormone (LH) from pituitary gonadotropes in response to short pulses of gonadotropin-releasing hormone (GnRH). The model includes binding of the hormone to its receptor, dimerization, interaction with a G protein, production of inositol 1,4, 5-trisphosphate, release of Ca(2+) from the endoplasmic reticulum, entrance of Ca(2+) into the cytosol via voltage-gated membrane channels, pumping of Ca(2+) out of the cytosol via membrane and endoplasmic reticulum pumps, and release of LH. Cytosolic Ca(2+) dynamics are simplified (i.e., oscillations are not included in the model), and it is assumed that there is only one pool of releasable LH. Despite these and other simplifications, the model explains the qualitative features of LH release in response to GnRH pulses of various durations and different concentrations in the presence and absence of external Ca(2+).
A review of surgical strategies for penile prosthesis implantation in patients with Peyronie’s disease

The introduction of the inflatable penile prosthesis (IPP) has revolutionized the treatment of patients with both Peyronie’s disease (PD) and erectile dysfunction (ED). A thorough literature review was performed in order to review the surgical strategies used to treat PD, using the PubMed online database with the keywords “penile prosthesis”, “surgical management” and “Peyronie’s disease”. Patient satisfaction rates of 72–100% and partner satisfaction rates of 89% have been reported in the literature, although strong preoperative education may be needed to prepare patients for risks such as penile shortening, seen in up to 54% of patients. Three-piece IPPs are most commonly used, and when comparing the two most popular models (AMS 700 CX vs. Coloplast Titan), no significant differences were seen in functional outcomes or patient satisfaction. Simple insertion of an IPP has been shown to resolve curvature in 33–90% of patients, but surgeons may often need to also utilize ancillary straightening procedures for residual curvatures. Manual modeling can correct residual curvature with an 86–100% success rate, but with a 4% risk of urethral injury. When the post-modeling residual curvature exceeds 30 degrees, a plaque-releasing incision or plication is recommended to further reduce curvature. Grafting is recommended if the resulting incisional defect is larger than two centimeters. Alternative straightening techniques such as plication prior to IPP insertion, endoscopic plaque resection, the “scratch technique” and bone saw plaque incision have also been described.
Clinical review: Present and future prospects of male fertility preservation for children and adolescents.

CONTEXT Rapid progress in fertility preservation strategies has led to the investigation of ways in which fertile gametes could be generated from cryopreserved immature testicular tissue. Childhood cancer patients remain the major group that can benefit from these techniques. Other potential candidates include patients undergoing gonadectomy and patients with Klinefelter's syndrome and cryptorchid testes. This review aims to present an overview of the current state of knowledge in experimental germ cell transplantation, testicular tissue transplantation, and germ cell culture as fertility preservation methods for males. METHODOLOGY We included English articles published in PubMed as well as personal files with the focus on studies including human or nonhuman material. MAIN FINDINGS Germ cell and testicular tissue transplantation demonstrate clinical options to mature germ cells from immature primate testicular tissue. The most promising approach involves autologous grafting of immature testicular tissue, whereas germ cell maturation in vitro provides the best strategies to overcome problems of cancer contamination in cryopreserved testicular tissue. Three-dimensional and organ culture systems offer the possibility to differentiate immature male germ cells up to the stage of elongated spermatids. Further characterization of early germ cell development in humans is needed to modify these systems for clinical use.
An online algorithm for segmenting time series

In recent years, there has been an explosion of interest in mining time-series databases. As with most computer science problems, representation of the data is the key to efficient and effective solutions. One of the most commonly used representations is piecewise linear approximation. This representation has been used by various researchers to support clustering, classification, indexing and association rule mining of time-series data. A variety of algorithms have been proposed to obtain this representation, with several algorithms having been independently rediscovered several times. In this paper, we undertake the first extensive review and empirical comparison of all proposed techniques. We show that all these algorithms have fatal flaws from a data-mining perspective. We introduce a novel algorithm that we empirically show to be superior to all others in the literature.
Multiple-Century Response of a Coupled Ocean-Atmosphere Model to an Increase of Atmospheric Carbon Dioxide

Abstract To speculate on the future change of climate over several centuries, three 500-year integrations of a coupled ocean-atmosphere model were performed. In addition to the standard integration in which the atmospheric concentration of carbon dioxide remains unchanged, two integrations are conducted. In one integration, the C02 concentration increases by 1% yr−1 (compounded) until it reaches four times the initial value at the 140th year and remains unchanged thereafter. In another integration, the C02 concentration also increases at the rate of 1% yr−1 until it reaches twice the initial value at the 70th year and remains unchanged thereafter. One of the most notable features of the C02-quadrupling integration is the gradual disappearance of thermohaline circulations in most of the model oceans during the first 250-year period, leaving behind wind-driven cells. For example, thermohaline circulation nearly vanishes in the North Atlantic during the fist 200 years of the integration. In the Weddell and R.
Role of angiotensin II receptor blockers in atherosclerotic plaque stability

Several clinical trials have shown that agents blocking the renin-angiotensin system reduce the incidence of acute ischaemic events. This effect was independent from blood pressure reduction and was presumably related to plaque stabilisation. With the aim of investigating potential mechanisms underlying this effect, carotid plaques were analysed in a recent study from patients randomised to treatment with the angiotensin receptor blocker irbesartan, or the diuretic chlorthalidone for 4 months before carotid endarterectomy. It was found that irbesartan decreased inflammatory infiltration, increased collagen content and downregulated prostaglandin E2-dependent metalloproteases as a consequence of suppression of inducible COX-2/prostaglandin E synthase. This article reviews the results of this study and the most recent evidence that supports the possibility that angiotensin II receptor blockers represent a novel therapy for plaque stabilisation.
Propensity Score Adjustment for UnmeasuredConfounding in Observational Studies

Adjusting for several unmeasured confounders is a challenging problem in the analysis of observational data. Information about unmeasured confounders is sometimes available from external validation data, such as surveys or secondary samples drawn from the same source population. In principal, the validation permits us to recover information about the missing data, but the difficulty is in eliciting a valid model for nuisance distribution of the unmeasured confounders. Motivated by a British study of the effects of trihalomethane exposure on full-term low birthweight, we describe a flexible Bayesian procedure for adjusting for a vector of unmeasured confounders using external validation data. We summarize the unmeasured confounders with a scalar summary score using the propensity score methodology of Rosenbaum and Rubin. The score has the property that it breaks the dependence between the exposure and unmeasured confounders within levels of measured confounders. To adjust for unmeasured confounding in a Bayesian analysis, we need only update and adjust for the summary score during Markov chain Monte Carlo simulation. We demonstrate that trihalomethane exposure is associated with increased risk of full-term low birthweight, and this association persists even after adjusting for eight unmeasured confounders. Empirical results from simulation illustrate that our proposed method eliminates bias from several unmeasured confounders, even in small samples.
A taxonomic review of the centipede genus Scolopendra Linnaeus, 1758 (Scolopendromorpha, Scolopendridae) in mainland Southeast Asia, with description of a new species from Laos

Abstract The centipede genus Scolopendra in mainland Southeast Asia is reviewed taxonomically based on morphological characters, informed by a molecular phylogenetic analysis using sequences from three mitochondrial and nuclear genes (COI, 16S rRNA and 28S rRNA). Eight nominal species of Scolopendra, namely Scolopendra morsitans Linnaeus, 1758, Scolopendra subspinipes Leach, 1816, Scolopendra dehaani Brandt, 1840, Scolopendra multidens Newport, 1844, Scolopendra calcarata Porat, 1876, Scolopendra japonica Koch, 1878, Scolopendra pinguis Pocock, 1891, and Scolopendra dawydoffi Kronmüller, 2012, are redescribed together with some revision of type materials. Geographical variation in each species has been compiled with reference to samples that span their distribution ranges in Southeast Asia and some parts of neighbouring areas such as East Asia, the Indian Ocean, and Africa. Comparative study of traditional taxonomic characters from external morphology provides further information to distinguish some closely related species. Scolopendra cataracta Siriwut, Edgecombe & Panha, sp. n. , is described from the southern part of Laos, with additional records in Thailand and Vietnam. The phylogenetic framework for Southeast Asian Scolopendra recognizes Scolopendra calcarata + Scolopendra pinguis, Scolopendra morsitans, and a Scolopendra subspinipes group that unites the other six species as the main clades. Within the Scolopendra subspinipes group, two monophyletic groups can be distinguished by having either slender or short, thick ultimate leg prefemora and different numbers of apical spines on the coxopleuron. Scolopendra arborea Lewis, 1982, is placed in subjective synonymy with Scolopendra dehaani. A survey of external morphology of the genital segments confirms its potential for improving species identification in Scolopendra. Some observations on biology and behaviour are recorded based on field surveys in this area.
Edops, a Primitive Rhachitomous Amphibian from the Texas Red Beds

A description is given of the skull and such postcranial material as is known of Edops craigi, a large labyrinthodont amphibian from the Wichita Permo-Carboniferous beds of Texas. The structure of the Edops skull shows this form to be a very primitive member of the Rhachitomi, approaching the embolomerous stage in many structural features.