Miracle-dz/UniFAR-FTUs huggingface dataset:
Neuroimaging of focal cortical dysplasia: neuropathological correlations.

Focal cortical dysplasia is a well-known cause of intractable epilepsy with early onset of seizures, and is potentially amenable to surgical therapy. It was first described by Taylor in 1971 as a peculiar malformative disorganisation of the neocortex characterised at histology by loss of cortical lamination and accompanied by giant, dysmorphic neurones and, most frequently, by "balloon cells" littered throughout the cortex and sub-cortical white matter. While in the past decades the term "cortical dysplasia" has referred to various malformations of cortical development, such as agyria, pachygyria, polymicrogyria, heterotopia and hemimegalencephaly, it is now widely accepted that the entity identified by Taylor should be considered separately, from both histological and neuroimaging standpoints. More recently, the recognition of various histological subtypes of focal cortical dysplasia characterised by different degrees of cortical disruption with or without cytological abnormalities has generated several classifications that are still unsatisfactory. With better magnetic resonance capability, subtle and very small focal cortical dysplasias may now be visualised and the differential magnetic resonance aspects of the histological subgroups can be established. We will discuss the problem of histopathological classification and magnetic resonance imaging differentiation of the various subtypes of focal cortical dysplasia in the light of personal data collected from a large series of epileptic patients who underwent surgery and had a histological diagnosis of focal cortical dysplasia.
When being disadvantaged grows into vengeance: The effects of asymmetry of interest and social rejection in social dilemmas

In public good dilemmas, group members often differ in the extent to which they benefit from provision of the public good (asymmetry of interest). In the current paper, we argue that people may readily accept such financial differences in interest when their social needs are met by being accepted by the others. When people are socially rejected, however, members having a low rather than a high interest in the public good may display negative emotional and retributive reactions. This reasoning was supported by the findings of a first experimental study in which we manipulated people's interest in the public good and social rejection. These effects were replicated in a second experimental study and it was further shown that this two-way interaction between social rejection and interest in the public good was moderated by people's social value orientation. The negative reactions to low interest (vs. high interest) in the public good when being socially rejected were especially prominent among group members with a proself orientation. Taken together, the current studies illustrate the importance of studying how financial and social needs interact to determine emotional and retributive actions in social dilemmas. Copyright © 2008 John Wiley & Sons, Ltd.
MaltParser: A language-independent system for data-driven dependency parsing

A process and an apparatus for melting solidified gel masses, in particular of photographic emulsions, which are introduced as solid pieces of any size or shape into a melting container having a perforated bottom and equipped with a tempering device, the gel mass when melted flowing through the openings in the bottom into a receiver underneath it, and being arranged and designed to prevent excessive exposure of the gel mass to heat. This is achieved by melting the layer of gel mass immediately above the bottom of the melting container with microwaves while the layers of gel mass situated above the aforesaid layer remain substantially uninfluenced by the radiation of microwaves.
Characterising the Inflation Targeting Regime in South Korea

This paper attempts at characterising South Korean monetary policy in the period of explicit inflation targeting started in 1999. We explain Korean interest rates in relation to an estimated macro-model, assuming that monetary policy is set optimally. This allows us to obtain the central bank's parameters in the policy objective function. During the IT regime, the data support that the Bank of Korea pursued optimal policy geared towards achieving price stability, with the degree of interest rate smoothing being estimated to be considerable. In addition, the central bank loss function is estimated to include negligible weights on output and exchange rate variability. JEL Classification: E52, E58, E61
Islamist moderation without democratization: the coming of age of the Moroccan Party of Justice and Development?

This article studies a novel factor relevant for the moderation of an Islamist party: the degree of dependency on a social movement organization. This question is examined in a case study analysing the evolution of the relationship between the Moroccan Islamist party, Party of Justice and Development (PJD), and its founding social movement organization. Over time, the PJD has been gaining autonomy, becoming more moderate and simultaneously gaining strength. Contemporaneously, liberalization in Morocco has been partially reversed, partly as a result of the rising Islamist strength. These findings suggest that it is the strength of the Islamist opposition, rather than its ideological rigidity, that makes MENA rulers reluctant to liberalize. We study the implications of these findings for European Union policy towards Islamist parties in the MENA region.
Biocontrol of Bactrocera oleae (Diptera: Tephritidae) with Metarhizium brunneum and its Extracts

ABSTRACT The susceptibility of preimaginal and adult olive fruit fly, Bactrocera oleae (Gmelin) (Diptera: Tephritidae), to a strain of the mitosporic ascomycete Metarhizium brunneum (Petch) (Hypocreales: Clavicipitaceae) and the insecticidal activity of its crude extract to olive fruit fly adults were investigated. Strain EAMb 09/01-Su caused 60% mortality to B. oleae adults, with average survival time (AST) of 8.8 d. In soil treatments against pupariating third-instar larvae, preimaginal B. oleae mortality reached 82.3%, whereas preimaginal mortality targeting puparia was 33.3%. The crude extract of EAMb 09/01-Su strain caused 80.0% adult mortality when administered per os, with AST of 27.7 h. The crude extract was demonstrated to be quite thermostable and photoresistant. These results indicate that M. brunneum EAMb 09/01-Su strain and its crude extract show potential to be used in an integrated pest management olive fruit fly management strategy targeting both adults and preimaginals.
Use of parecoxib by continuous subcutaneous infusion for cancer pain in a hospice population

Objectives To characterise the use of the parenteral non-steroidal anti-inflammatory drug parecoxib when given by continuous subcutaneous infusion (CSCI) in a hospice population. Clinical experience suggests parecoxib CSCI may be of benefit in this population, but empirical evidence in relation to its safety and efficacy is lacking. Methods Retrospective chart review of patients with a cancer diagnosis receiving parecoxib CSCI from 2008 to 2013 at the Marie Curie Hospice, Belfast. Data were collected on treatment regime, tolerability and, in patients receiving at least 7 days treatment, baseline opioid dose and changes in pain scores or opioid rescue medication requirements. Results Parecoxib CSCI was initiated in 80 patients with a mean administration of 17.9 days (median 11, range 1–94). When used for a period of 7 days, there was a statistically significant reduction in pain scores (p=0.002) and in the number of rescue opioid doses required (p=0.001), but no statistically significant opioid-sparing effect (p=0.222). It was generally well tolerated, although gastrointestinal, renal adverse effects and local site irritation were reported. Conclusions Parecoxib may have a valuable place in the management of cancer pain, especially towards the end of life when oral administration is no longer possible and CSCI administration is relied on. Further studies into the efficacy and tolerability of parecoxib CSCI are merited.
A comparison of the efficacy and acceptability of group versus individual cognitive behaviour therapy in the treatment of panic disorder and agoraphobia in primary care

Panic disorder and agoraphobia is a prevalent clinical condition which places heavy demands on treatment resources in primary care. The efficient delivery of evidence-based psychological treatment for this disorder is therefore important. Previous research has investigated both individual and group treatment formats for cognitive behaviour therapy (CBT) for panic disorder and agoraphobia. These two modalities of treatment delivery are, however, rarely compared within the same study format. Also little is known of patients' preferences regarding treatment delivery formats. The present study investigated the relative efficacy of a group treatment CBT and an individual treatment CBT in comparison with a waiting list control group in the treatment of panic disorder with or without agoraphobia in primary care. Ninety-seven patients suffering from DSM-IV panic disorder with or without agoraphobia were randomly allocated to receive either group CBT, individual CBT, or waiting list control. All patients were seen by the same therapist and all received an identical treatment manual. Treatment response was measured by blind assessor, therapist and patient-rated measures of anxiety, depression, and agoraphobic avoidance, and was analysed in terms of both traditional statistical significance and clinical significance of outcome. At treatment end-point, in terms of traditional statistical significance, both the group and individual CBT were significantly superior to waiting list control but did not differ significantly from each other. When clinical significance of outcome at treatment end-point was considered, individual CBT showed a significant advantage over both group CBT and waiting list control. At 3-month follow-up, however, the individual CBT treatment group showed significant superiority to the group CBT treatment on clinical significance of outcome on one outcome measure only. This was principally due to a reduction in the proportion of patients achieving criteria of clinically significant change in the individual CBT treatment group over the 3-month follow-up period. When given a free choice of group or individual CBT at the end of the waiting list period, the overwhelming majority (95%) of the waiting list patients chose individual CBT. The implications of these findings for future research and for wider clinical practice are discussed. Copyright © 2004 John Wiley & Sons, Ltd.
The role of personality traits in online consumer complaint behavior and service recovery expectation

To date, the literature on service failure and recovery has tended to be focused on bricks-and-mortar stores. In this study the relationships among service failures, consumer complaint behaviors, and service recovery expectations in an online setting were investigated. Data were collected from 252 respondents in a questionnaire survey. Results of multiple regression analysis show that personality traits in terms of Type A and locus of control may moderate the relationships among e-service failures, consumer complaint behaviors, and service recovery expectations. When e-service failures occur, Type A and internally oriented consumers engage in aggressive complaint behaviors and expect high service recovery efforts. Conversely, Type B and externally oriented consumers tend to tolerate e-service failures and refrain from complaining. Finally, theoretical and managerial implications are discussed.
The Travels of Critiques of Neoliberalism: Urban Experiences from the “Borderlands”

This article contributes to the ongoing scrutiny of the travels of critiques of neoliberalism in urban studies. Using the case of a state-led urban regeneration program implemented in Portugal since 2000, the Polis Program, the article weighs in on meta-analytical discussions about the hegemonic status of neoliberalism as a theoretical concept and as an analytical framework and on discussions about the travels of dominant critiques of neoliberalism beyond the sites of epistemological production. The article argues that the current analytical overinvestment in neoliberalism may obscure important drivers of contemporary urbanization and that recourse to a diversity of concepts may be a more profitable line of inquiry. The article suggests that current efforts at epistemological renewal within urban studies benefit from taking up cities in the “borderlands” of urban theory as relevant cases in their own right. The article offers further considerations on the purchase of neoliberalism in contemporary urban literature. [Key words: neoliberalism, critiques, urban theory, urban planning and policy, Portugal, Polis Program]
Inducing Synchronous Grammars with Slice Sampling

This paper describes an efficient sampler for synchronous grammar induction under a non-parametric Bayesian prior. Inspired by ideas from slice sampling, our sampler is able to draw samples from the posterior distributions of models for which the standard dynamic programing based sampler proves intractable on non-trivial corpora. We compare our sampler to a previously proposed Gibbs sampler and demonstrate strong improvements in terms of both training log-likelihood and performance on an end-to-end translation evaluation.
The Effect of Dynamic Geometry Software on Student Mathematics Teachers' Spatial Visualization Skills.

Geometry is the study of shape and space. Without spatial ability, students cannot fully appreciate the natural world. Spatial ability is also very important for work in various fields such as computer graphics, engineering, architecture, and cartography. A number of studies have demonstrated that technology has an important potential to develop spatial skills. In the present study, the effect of dynamic geometry software (DGS) Cabri 3D on student mathematics teachers’ spatial skills was examined. The study used a one-group pretest–intervention– posttest experimental design. In this context, 40 student mathematics teachers took “Purdue Spatial Visualization” (PSV) test as pretest at the beginning of the study, and then some implementations were carried out with these students by using Cabri 3D software for 8 weeks. The PSV test was retaken by students at the end of the study. That if there was a meaningful difference between the pretest and posttest results was examined by using paired sample t test. The findings demonstrated that these computer supported activities contributed to development student mathematics teachers’ spatial skills.
Atherogenic role of elevated CE transfer from HDL to VLDL(1) and dense LDL in type 2 diabetes : impact of the degree of triglyceridemia.

Plasma cholesteryl ester transfer protein (CETP) facilitates intravascular lipoprotein remodeling by promoting the heteroexchange of neutral lipids. To determine whether the degree of triglyceridemia may influence the CETP-mediated redistribution of HDL CE between atherogenic plasma lipoprotein particles in type 2 diabetes, we evaluated CE mass transfer from HDL to apoB-containing lipoprotein acceptors in the plasma of type 2 diabetes subjects (n=38). In parallel, we investigated the potential relationship between CE transfer and the appearance of an atherogenic dense LDL profile. The diabetic population was divided into 3 subgroups according to fasting plasma triglyceride (TG) levels: group 1 (G1), TG<100 mg/dL; group 2 (G2), 100200 mg/dL. Type 2 diabetes patients displayed an asymmetrical LDL profile in which the dense LDL subfractions predominated. Plasma levels of dense LDL subfractions were strongly positively correlated with those of plasma triglyceride (TG) (r=0.471; P:=0.0003). The rate of CE mass transfer from HDL to apoB-containing lipoproteins was significantly enhanced in G3 compared with G2 or G1 (46.2+/-8.1, 33.6+/-5.3, and 28.2+/-2.7 microg CE transferred. h(-1). mL(-1) in G3, G2, and G1, respectively; P:<0.0001 G3 versus G1, P:=0.0001 G2 versus G1, and P:=0.02 G2 versus G3). The relative capacities of VLDL and LDL to act as acceptors of CE from HDL were distinct between type 2 diabetes subgroups. LDL particles represented the preferential CE acceptor in G1 and accounted for 74% of total CE transferred from HDL. By contrast, in G2 and G3, TG-rich lipoprotein subfractions accounted for 47% and 72% of total CE transferred from HDL, respectively. Moreover, the relative proportion of CE transferred from HDL to VLDL(1) in type 2 diabetes patients increased progressively with increase in plasma TG levels. The VLDL(1) subfraction accounted for 34%, 43%, and 52% of total CE transferred from HDL to TG-rich lipoproteins in patients from G1, G2, and G3, respectively. Finally, dense LDL acquired an average of 45% of total CE transferred from HDL to LDL in type 2 diabetes patients. In conclusion, CETP contributes significantly to the formation of small dense LDL particles in type 2 diabetes by a preferential CE transfer from HDL to small dense LDL, as well as through an indirect mechanism involving an enhanced CE transfer from HDL to VLDL(1), the specific precursors of small dense LDL particles in plasma.
The role of leader-member exchange in high turnover work environments

Purpose – To assess the role of leader‐member exchange (LMX) in affecting voluntary turnover in a high turnover work context.Design/methodology/approach – Following consideration of traditional predictors of employee turnover, how LMX is related to voluntary turnover is examined among 207 over‐the‐road truck drivers using a telephone survey.Findings – Leader member exchange is found to be nonlinearly related to turnover such that turnover is lowest when LMX is moderate (i.e. both “bad” and “good” LMX are associated with higher levels of turnover). Research limitations/implications – Findings indicate that LMX and other antecedents should be examined for nonlinear relationships to turnover. This research may help to bridge the gap between turnover research and that associated with supervision and leadership.Practical implications – These study results suggest that unrealistic expectations should not be formed regarding the power of any single factor (e.g. LMX) to reduce turnover.Originality/value – This pap.
RSC-dependent constructive and destructive interference between opposing arrays of phased nucleosomes in yeast

RSC and SWI/SNF are related ATP-dependent chromatin remodeling machines that move nucleosomes, regulating access to DNA. We addressed their roles in nucleosome phasing relative to transcription start sites in yeast. SWI/SNF has no effect on phasing at the global level. In contrast, RSC depletion results in global nucleosome repositioning: Both upstream and downstream nucleosomal arrays shift toward the nucleosome-depleted region (NDR), with no change in spacing, resulting in a narrower and partly filled NDR. The global picture of RSC-depleted chromatin represents the average of a range of chromatin structures, with most genes showing a shift of the +1 or the −1 nucleosome into the NDR. Using RSC ChIP data reported by others, we show that RSC occupancy is highest on the coding regions of heavily transcribed genes, though not at their NDRs. We propose that RSC has a role in restoring chromatin structure after transcription. Analysis of gene pairs in different orientations demonstrates that phasing patterns reflect competition between phasing signals emanating from neighboring NDRs. These signals may be in phase, resulting in constructive interference and a regular array, or out of phase, resulting in destructive interference and fuzzy positioning. We propose a modified barrier model, in which a stable complex located at the NDR acts as a bidirectional phasing barrier. In RSC-depleted cells, this barrier has a smaller footprint, resulting in narrower NDRs. Thus, RSC plays a critical role in organizing yeast chromatin.
Barriers to the Innovation Process: Four Case Studies of Differentiated Staffing

Researchers at the Center for the Advanced Study of Educational Administration spent the 1970-71 school year conducting on-site observa tional studies of four schools in their first year of implementing Differenti ated Staffing. This article describes the characteristic course of events in the schools during that year and summarizes the chronic problems of change revealed by the observations. In addition to their association with CASEA, W. W. Charters, Jr., is Professor of Educational Administration and Roland J. Pellegrin is Professor of Sociology at the University of Oregon.
Distractor Filtering in Media Multitaskers

A growing amount of modern media is consumed simultaneously, a phenomenon known as ‘media multitasking’. Individuals who regularly engage in this activity, heavy media multitaskers (HMMs), are more affected by irrelevant information that can intrude into a primary task than are light media multitaskers (LMMs—Ophir et al, 2009 Proceedings of the National Academy of Sciences of the USA 106 15583). However, the locus of this deficit is unknown, as previous research is consistent with both memory and attentional explanations. Here, we isolated attentional processes by employing a singleton distractor task with low working-memory demands. In this task, LMMs used top – down information to improve their performance, yet HMMs did not. This difference in performance in an established attentional capture task argues for the presence of attentional differences in HMMs and is consistent with the idea that HMMs maintain a wider attentional scope than LMMs, even when instructed otherwise.
Economic narratives and international migration under liberalization: lost in translation

Abstract Whereas orthodox economists supported the liberalization of goods and capital markets in the current global era, they typically assumed away the need to liberalize labour markets at an international level. The unexpected rise and then persistence of international immigration indicated the shortcomings of the orthodox account in theory and practice. Various recurring and contradictory or unsupported narratives were developed to ‘explain away’ the necessity or desirability of a policy of free migration, and this in spite of an ideology that otherwise promoted liberalization and choice in matters affecting goods and factor markets. There was, finally, a normative contradiction at the core of the orthodox account.
Preference structures and behavioral consistency in negotiations 1

In this paper, we report results of the analysis of about 4,700 multi-attribute utility functions elicited during experiments with the Internet-based Negotiation Support System Inspire. The empirical results indicate that common assumptions of decision analysis, like monotonicity of single-attribute utilities or decreasing marginal utilities, are violated in a significant number of cases. Nevertheless, many structural properties of utility functions are clearly reflected in the outcomes of negotiations. On the other hand, behavior during the negotiation process contradicts the preferences implied in the utility functions in about 25% of all cases. Paper presented at the MCDM world conference, Whistler Mountain, Canada, August 6-11, 2004. I would like to thank Vivi Nastase for extracting the Inspire negotiation records. This research is part of the eNegotiation project supported by the Social Sciences and Human Ressources Council, Canada. http://interneg.org/