Miracle-dz/UniFAR-FTUs huggingface dataset:
Human Factors Contributions to Knowledge Elicitation

Objective: The objective of this article is to lay out contributions of human factors to knowledge elicitation (KE) methodology. Background: The background is historical, dating to about 1985, and involves the convergence of expert systems with applied psychology and cognitive psychology. Method: The method is a literature review, focusing on past issues of Human Factors. Results: Human factors researchers have contributed significantly to KE methodology. However, KE methodology “belongs to” a number of communities of practice and has applications that transcend individual disciplines. Conclusion: Knowledge elicitation, thought of as a kind of cognitive task analysis, grows in importance with the increasing use of information technology to form complex sociotechnical work systems and the increasing importance of expertise to knowledge-based organizations. Application: I discuss some open issues for further research and methodological investigation.
Blind Compressive Sensing Framework for Collaborative Filtering

Existing works based on latent factor models have focused on representing the rating matrix as a product of user and item latent factor matrices, both being dense. Latent (factor) vectors define the degree to which a trait is possessed by an item or the affinity of user towards that trait. A dense user matrix is a reasonable assumption as each user will like/dislike a trait to certain extent. However, any item will possess only a few of the attributes and never all. Hence, the item matrix should ideally have a sparse structure rather than a dense one as formulated in earlier works. Therefore we propose to factor the ratings matrix into a dense user matrix and a sparse item matrix which leads us to the Blind Compressed Sensing (BCS) framework. We derive an efficient algorithm for solving the BCS problem based on Majorization Minimization (MM) technique. Our proposed approach is able to achieve significantly higher accuracy and shorter run times as compared to existing approaches.
Long-term effectiveness and prediction of treatment outcome in cognitive behavioral therapy and sertraline for late-life anxiety disorders

ABSTRACT Background: Although anxiety disorders are prevalent in older adults, randomized controlled trials of treatment effectiveness for late-life anxiety are scarce and have focused primarily on the effectiveness of psychotherapeutic interventions. However, recent findings suggest that in some cases, pharmacological treatment may be more beneficial for late-life anxiety disorders. As yet, there have been no systematic studies investigating prognostic factors for the outcome of cognitive behavioral therapy (CBT) and pharmacotherapy for late-life anxiety. The objective of the present study was to study long-term treatment outcomes and to explore differential predictors for both short-term and long-term treatment outcomes of sertraline and CBT for late-life anxiety disorders. Methods: Participants of a randomized controlled trial (RCT) comparing sertraline and CBT for the treatment of late-life anxiety were contacted one year after completing their treatment, so that predictors for both short-term and long-term treatment outcome could be established. Results: Sertraline showed a greater reduction of symptoms than CBT on anxiety (Hamilton Anxiety Rating Scale; HARS) and worry (Worry Domain Questionnaire) ratings at one-year follow-up. The strongest predictor for short-term CBT outcome was poor perceived health, explaining 40% of the variance in post-treatment residual gain scores on the HARS. The strongest predictor for long-term CBT outcome was neuroticism, explaining 20% of the variance in residual gain scores at one-year follow-up. Analyses revealed no significant predictors for treatment outcome in sertraline participants. Conclusions: Our study suggests that long-term use of sertraline might be more beneficial for late-life anxiety than a 15-week CBT program. Poor perceived health and neuroticism are predictive of less improvement after CBT in anxious older adults. Implications of these findings are discussed.
Current state of intensive hemodialysis: a comparative review of benefits and barriers.

The current interest in intensive hemodialysis (HD) was born out of the impasse in an effort to improve survival and quality of life (QOL) in patients with end-stage renal disease. In this review, we have summarized the emerging data of intensive HD on (i) survival, (ii) cardiovascular outcomes, (iii) phosphate balance and (iv) QOL. Although there is a consistent and compelling signal favoring intensive HD, it is important to balance the enthusiasm with the significant amount of perceived and actual barriers for our patients to overcome to receive or perform intensive HD. For an individual patient, the answer to the question 'What is the best form of intensive hemodialysis? ' should be a consideration between the benefits sought and the obstacles in attaining intensive HD. In the future, changes in dialysis technology, healthcare delivery and education strategy are needed to allow the majority of patients to receive optimal renal replacement therapy.
The Influence of the Internet on European Journalism

This study investigates how European journalists evaluate the changes that have occurred in their profession since the Internet has been integrated in newsrooms. How do journalists perceive the features and innovations associated with the Internet? What are the principal changes in the profession? Do practitioners believe that the quality of journalism has been raised or lowered? To answer to these research questions, we carried out a survey across 11 European countries–Cyprus, Estonia, Finland, Greece, Ireland, Italy, Lithuania, United Kingdom, Slovenia, Spain, Sweden–of 239 journalists, working for 40 of the most-read print/online news outlets in these countries. The survey shows that the opportunity to use the Internet to reinforce the social functions of journalism has not been fully recognised.
Genetic Variants of Neurotransmitter-Related Genes and miRNAs in Egyptian Autistic Patients

Autism is a neurodevelopmental disorder with indisputable evidence for a genetic component. This work studied the association of autism with genetic variations in neurotransmitter-related genes, including MAOA uVNTR, MAOB rs1799836, and DRD2 TaqI A in 53 autistic patients and 30 healthy individuals. The study also analyzed sequence variations of miR-431 and miR-21. MAOA uVNTR was genotyped by PCR, MAOB and DRD2 polymorphisms were analyzed by PCR-based RFLP, and miR-431 and miR-21 were sequenced. Low expressing allele of MAOA uVNTR was frequently higher in female patients compared to that in controls (OR = 2.25). MAOB G allele frequency was more significantly increased in autistic patients than in controls (P < 0.001 for both males and females). DRD2 A1+ genotype increased autism risk (OR = 5.1). Severity of autism tends to be slightly affected by MAOA/B genotype. Plasma MAOB activity was significantly reduced in G than in A allele carrying males. There was no significant difference in patients and maternal plasma MAOA/B activity compared to controls. Neither mutations nor SNPs in miR-431 and miR-21 were found among studied patients. This study threw light on some neurotransmitter-related genes suggesting their potential role in Autism pathogenesis that warrants further studies and much consideration.
Source Reliability and the Conjunction Fallacy

Information generally comes from less than fully reliable sources. Rationality, it seems, requires that one take source reliability into account when reasoning on the basis of such information. Recently, Bovens and Hartmann (2003) proposed an account of the conjunction fallacy based on this idea. They show that, when statements in conjunction fallacy scenarios are perceived as coming from such sources, probability theory prescribes that the "fallacy" be committed in certain situations. Here, the empirical validity of their model was assessed. The model predicts that statements added to standard conjunction problems will change the incidence of the fallacy. It also predicts that statements from reliable sources should yield an increase in fallacy rates (relative to unreliable sources). Neither the former (Experiment 1) nor the latter prediction (Experiment 3) was confirmed, although Experiment 2 showed that people can derive source reliability estimates from the likelihood of statements in a manner consistent with the tested model. In line with the experimental results, model fits and sensitivity analyses also provided very little evidence in favor of the model. This suggests that Bovens and Hartmann's present model fails to explain fully people's judgements in standard conjunction fallacy tasks.
Unified Skeletal Animation Reconstruction with Multiple Kinects

We present a new method for reconstructing a uniﬁed skeletal animation with multiple Kinects. Our method is able to reconstruct the uniﬁed skeletal animation from Kinect data over 360 degrees. We make use of all three streams: RGB, depth and skeleton, along with the joint tracking conﬁdence state from Microsoft Kinect SDK to ﬁnd the correctly oriented skeletons and merge them together to get a uniform animation. Our method is easy to implement and provides a simple solution of creating a 360 degree plausible uniﬁed skeletal animation that would not be possible to capture with a single Kinect due to occlusions, tracking failures, and ﬁeld of view constraints. Categories and Subject Descriptors (according to ACM CCS) : I.4. 8 [Image Processing and Computer Vision]: Scene Analysis—Motion, Sensor Fusion
E1A Sensitizes Cancer Cells to TRAIL-Induced Apoptosis through Enhancement of Caspase Activation

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) has been shown to induce apoptosis of cancer cells. Sensitization of cancer cells to TRAIL, particularly TRAIL-resistant cancer cells, could improve the effectiveness of TRAIL as an anticancer agent. The adenovirus type 5 E1A that associates with anticancer activities including sensitization to apoptosis induced by tumor necrosis factor is currently being tested in clinical trials. In this study, we investigated the sensitivity to TRAIL in the E1A transfectants ip1-E1A2 and 231-E1A cells and the parental TRAIL-resistant human ovarian cancer SKOV3.ip1 and TRAIL-sensitive human breast cancer MDA-MB-231 cells. The results indicated that the percentage of TRAIL-induced apoptotic cells was significantly higher in the E1A transfectants of both cell lines than it was in the parental cell lines. To further investigate the cellular mechanism of this effect, we found that E1A enhances TRAIL-induced activation of caspase-8, caspase-9, and caspase-3. Inhibition of caspase-3 activity by a specific inhibitor, Z-DEVD-fmk, abolished TRAIL-induced apoptosis. In addition, E1A enhanced TRAIL expression in ip1-E1A2 cells, but not in 231-E1A cells, and the anti-TRAIL neutralizing antibody N2B2 blocked the E1A-mediated bystander effect in vitro. Taken together, these results suggest that E1A sensitizes both TRAIL-sensitive and TRAIL-resistant cancer cells to TRAIL-induced apoptosis, which occurs through the enhancement of caspase activation; activation of caspase-3 is required for TRAIL-induced apoptosis; and E1A-induced TRAIL expression is involved in the E1A-mediated bystander effect. Combination of E1A and TRAIL could be an effective treatment for cancer.
Yoga as an adjunctive treatment for posttraumatic stress disorder: a randomized controlled trial.

BACKGROUND More than a third of the approximately 10 million women with histories of interpersonal violence in the United States develop posttraumatic stress disorder (PTSD). Currently available treatments for this population have a high rate of incomplete response, in part because problems in affect and impulse regulation are major obstacles to resolving PTSD. This study explored the efficacy of yoga to increase affect tolerance and to decrease PTSD symptomatology. METHOD Sixty-four women with chronic, treatment-resistant PTSD were randomly assigned to either trauma-informed yoga or supportive women's health education, each as a weekly 1-hour class for 10 weeks. Assessments were conducted at pretreatment, midtreatment, and posttreatment and included measures of DSM-IV PTSD, affect regulation, and depression. The study ran from 2008 through 2011. RESULTS The primary outcome measure was the Clinician-Administered PTSD Scale (CAPS). At the end of the study, 16 of 31 participants (52%) in the yoga group no longer met criteria for PTSD compared to 6 of 29 (21%) in the control group (n = 60, χ²₁ = 6.17, P = .013). Both groups exhibited significant decreases on the CAPS, with the decrease falling in the large effect size range for the yoga group (d = 1.07) and the medium to large effect size decrease for the control group (d = 0.66). Both the yoga (b = -9.21, t = -2.34, P = .02, d = -0.37) and control (b = -22.12, t = -3.39, P = .001, d = -0.54) groups exhibited significant decreases from pretreatment to the midtreatment assessment. However, a significant group × quadratic trend interaction (d = -0.34) showed that the pattern of change in Davidson Trauma Scale significantly differed across groups. The yoga group exhibited a significant medium effect size linear (d = -0.52) trend. In contrast, the control group exhibited only a significant medium effect size quadratic trend (d = 0.46) but did not exhibit a significant linear trend (d = -0.29). Thus, both groups exhibited significant decreases in PTSD symptoms during the first half of treatment, but these improvements were maintained in the yoga group, while the control group relapsed after its initial improvement. DISCUSSION Yoga significantly reduced PTSD symptomatology, with effect sizes comparable to well-researched psychotherapeutic and psychopharmacologic approaches. Yoga may improve the functioning of traumatized individuals by helping them to tolerate physical and sensory experiences associated with fear and helplessness and to increase emotional awareness and affect tolerance. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT00839813.
Energy-Efficient Remote Temperature Monitoring System for Patients Based on GSM Modem and Microcontroller

— This study presents a real-time remote monitoring system (RTRMS) for the temperature of patients admitted to hospitals. A GSM modem was interfaced with microcontroller PIC16F877A to alerts physicians in real time via short message service (SMS) in emergency cases when the temperature of a patient rises. A sleep/wake energy-efficient algorithm has been implemented inside the microcontroller to reduce the power consumption of GSM and microcontroller. The microcontroller and GSM modem can be in a sleep mode when the temperature of a patient is steady. Consequently, power consumption can be improved and battery lifespan can be prolonged for RTRMS. In addition, the measurement accuracy was confirmed relative to the benchmark (digital thermometer) based on the mean absolute error (MAE). Results show that the proposed RTRMS is achieved 99% power savings relative to traditional RTRMS (i.e., without sleep/wake algorithm). The obtained MAE of 0.205 suggested a close agreement between the benchmark and the proposed RTRMS. The proposed system is a real-time monitoring, applicable, cost-effective, and efficient means for transmitting information because it utilizes the advantages of the infrastructure of GSM network and features a ready mobile device connected with physicians. In addition, the RTRMS can be used in numerous applications and for others parameters rather than temperature with simple modifications (e.g., heart rate, respiratory rate, and electrocardiography for monitoring health care, rehabilitation for monitoring gait speed and cadence, and muscle activity and patient fall detection for safety monitoring).
High Density Lipoprotein Uptake by Scavenger Receptor SR-BII*

Scavenger receptor class B, type I (SR-BI) mediates selective uptake of high density lipoprotein (HDL) lipids. It is unclear whether this process occurs at the cell membrane or via endocytosis. Our group previously identified an alternative mRNA splicing variant of SR-BI, named SR-BII, with an entirely different, yet highly conserved cytoplasmic C terminus. In this study we aimed to compare HDL uptake by both isoforms. Whereas SR-BI was mainly (∼70%) localized on the surface of transfected Chinese hamster ovary cells, as determined by biotinylation, HDL binding at 4 °C, and studies of enhanced green fluorescent protein-tagged SR-BI/II fusion proteins, the majority of SR-BII (∼80-90%) was expressed intracellularly. The cellular distribution of SR-BI was not affected by deletion of the C terminus, which suggests that the distinct C terminus of SR-BII is responsible for its intracellular expression. Pulse-chase experiments showed that SR-BII rapidly internalized HDL protein, whereas in the case of SR-BI most HDL protein remained surface bound. Like its ligand, SR-BII was more rapidly endocytosed compared with SR-BI. Despite more rapid HDL uptake by SR-BII than SR-BI, selective cholesteryl ether uptake was significantly lower. Relative to their levels of expression at the cell surface, however, both isoforms mediated selective uptake with similar efficiency. HDL protein that was internalized by SR-BII largely co-localized with transferrin in the endosomal recycling compartment. Within the endosomal recycling compartment of SR-BII cells, there was extensive co-localization of internalized HDL lipid and protein. These results do not support a model that selective lipid uptake by SR-BI requires receptor/ligand recycling within the cell. We conclude that SR-BII may influence cellular cholesterol trafficking and homeostasis in a manner that is distinct from SR-BI.
Motor development in school‐aged children with 22q11 deletion (velocardiofacial/DiGeorge syndrome)

The aim of this study was to compare the motor development of primary school children (age 5–14y) with a 22q11 deletion (del22q11) group and a control group. The effects of a congenital heart defect (CHD) and IQ on motor development were additionally studied within the del22q11 group. Motor development of 37 children with a del22q11 (20 males, 17 females; mean age 9y 4mo, range 5y 9mo–13y 3mo) and 34 controls (23 males, 11 females; mean age 9y 1mo, range 4y 8mo–13y 6mo) was assessed with the Bruininks–Oseretsky Test of Motor Proficiency. The del22q11 group showed a significant deficit in motor functioning compared with the control group (p < 0.01). Within the del22q11 group there was a significant effect of IQ on motor performance, but no effect of CHD was found. To conclude, primary school children with a del22q11 syndrome showed a significant deficit in motor performance compared with a control group. A significant effect of IQ on motor performance in del22q11 was found.
Effects of Two Different Weight Training Programs on Swimming Performance and Muscle Enzyme Activities and Fiber Type

Abstract Belfry, GR, Noble, EG, and Taylor, AW. Effects of two different weight training programs on swimming performance and muscle enzyme activities and fiber type. J Strength Cond Res 30(2): 305–310, 2016—The effects of 2 different weight training programs incorporating bench press (BP) and pullover (PO) exercises on swimming performance, power, enzyme activity, and fiber type distribution were studied on 16 men (age = 23 ± 4 years). A 30-second group (n = 6) performed up to 20 repetitions of BP and PO in 30 seconds. The 2-minute group (n = 6) performed a maximum of 80 repetitions of BP and PO in 2 minutes. As participants reached the prescribed 20 or 80 repetitions, the weight was increased 4.5 kg. A third group (n = 4) served as nontraining controls. Exercise groups trained 3 times per week for 6 weeks. Maximal effort swims of 50 and 200 yd were performed before and after training. Training resulted in increases in work on both exercises in both groups pre- to post-training (BP 30 seconds, 722 ± 236–895 ± 250 kg; PO 30 seconds, 586 ± 252–1,090 ± 677 kg; and BP 2 minutes, 1,530 ± 414–1,940 ± 296; PO 2 minutes, 1,212 ± 406–2,348 ± 194, p ⩽ 0.05). Swim performances of the 30-second group improved for both the 50-yd (32.0 ± 6.9 seconds, 30.0 ± 5.9 seconds, p ⩽ 0.05) and 200-yd swims 200.0 ± 54 seconds, 182 ± 45.1 seconds (p ⩽ 0.05), whereas 2-minute training improved only the 200-yd swim (198.3 ± 32.3 seconds, 186.2 ± 32.2 seconds). No changes in swim performance were observed for the control group. Triceps muscle succinate dehydrogenase activities increased (pre 3.48 ± 1.1 &mgr;mol·g−1 wet weight per minute, post 6.25 ± 1.5 &mgr;moles·g−1 wet weight per minute, p ⩽ 0.05) in only the 30-second training group, whereas phosphofructokinase activities and fiber type distribution did not change in either training group. This study has demonstrated that a 30-second 20-repetition weight training program, specific to the swimming musculature without concurrent swim training, improves swimming performances at both 50- and 200-yd distances.
A Novel Arabic Text Steganography Method Using Letter Points and Extensions

This paper presents a new steganography approach suitable for Arabic texts. It can be classified under steganography feature coding methods. The approach hides secret information bits within the letters benefiting from their inherited points. To note the specific letters holding secret bits, the scheme considers the two features, the existence of the points in the letters and the redundant Arabic extension character. We use the pointed letters with extension to hold the secret bit ‘one’ and the un-pointed letters with extension to hold ‘zero’. This steganography technique is found attractive to other languages having similar texts to Arabic such as Persian and Urdu. Keywords — Arabic text, Cryptography, Feature coding, Information security, Text steganography, Text watermarking.
Identity threat and stigma in cancer patients

Cancer stigma has undergone an important transformation in recent decades. In general, this disease no longer fits squarely into Goffman’s classic taxonomy of stigmatized conditions. This review will demonstrate that, with important adaptations, an identity-threat model of stigma can be used to organize cancer stigma research post-Goffman. This adapted model postulates that one’s personal attributions, responses to situational threat, and disease/treatment characteristics can be used to predict identity threat and well-being of individuals with cancer. Implications for further research and clinical practice are discussed.