Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Status of Conventional Charmonium Spectroscopy

Based on data samples taken by the BESIII, Belle, KEDR and LHCb experiments, many measurements on conventional charmonium spectroscopy were finished in the past years. Some of recent results, such as precise measurements of J/ψ and ψ(2S ) masses, the J/ψ decay width, the J/ψ and ψ(2S ) electronic widths, two-photon width of χc0,2 meson, the χc1,2 resonance parameters with the decays χc0,2 → J/ψµ+µ−, the ηc resonance parameters and observations of X(3823) and X*(3860), were reported.
To Assess Causality Using WHO-UMC Criteria & Identify the Offending Drug / Drugs

DOI: 10.21276/sjams.2018. 6.5. 78 Abstract: This is a prospective as well as retrospective observational study jointly conducted in the Department of Pharmacology and ART centre of N.S. C.B. Medical College Jabalpur M.P. after the approval of Institutional Ethics Committee. 121 (46.5%) patients received TLE regimen, out of which 99 (45%) patients developed ADRs. Maximum 220 (51.7%) ADRs occurred in TLE regimen with the female preponderance of 64% followed by 157 (37%) ADRs due to ZLN. A significant association was found between females’ ADR and TLE regimen. 122 (55.5%) ADRs were probable and 98 (44.5%) ADRs were possible by WHO-UMC causality assessment scale.
Strain differences in basal and cocaine-evoked dopamine dynamics in mouse striatum.

In vivo microdialysis was used to characterize basal dopamine (DA) dynamics and cocaine-evoked DA levels in the striatum of 129/Sv-ter, C57BL/6J, DBA/2J, and Swiss-Webster mice. Basal dialysate levels of DA did not differ in the four strains tested. Similarly, the no net flux method of quantitative microdialysis revealed no difference in extracellular levels between strains. However, the in vivo extraction fraction of DA was significantly less in 129/Sv-ter (53%) mice compared with C57BL/6J (68%), DBA/2J (69%), and Swiss-Webster (67%) mice, indicating a lower rate of basal DA uptake in the 129/Sv-ter strain. Perfusion of K(+) (60 and 100 mM) through the microdialysis probe significantly increased dialysate DA levels and there was no difference between strains in the magnitude of this effect. The acute administration of cocaine (5-20 mg/kg i.p.) increased DA levels in the four strains tested. Cocaine-evoked DA levels (in nanomoles) were significantly greater in 129/Sv-ter compared with C57BL/6J, DBA/2J, or Swiss-Webster mice after administration of either 5, 10, or 20 mg/kg cocaine. However, the percentage increase in DA did not differ across strains. These data demonstrate that there are strain-related differences in basal DA dynamics in the striatum of the mouse. Basal DA uptake was reduced in striatum of 129/Sv-ter mice compared with C57BL/6J, DBA/2J, or Swiss-Webster mice. In addition, the response of DA levels to cocaine may be enhanced in 129/Sv-ter compared with C57BL/6J, DBA/2J, or Swiss-Webster mice.
Multi-instance Multi-label Learning for Relation Extraction

Distant supervision for relation extraction (RE) -- gathering training data by aligning a database of facts with text -- is an efficient approach to scale RE to thousands of different relations. However, this introduces a challenging learning scenario where the relation expressed by a pair of entities found in a sentence is unknown. For example, a sentence containing Balzac and France may express BornIn or Died, an unknown relation, or no relation at all. Because of this, traditional supervised learning, which assumes that each example is explicitly mapped to a label, is not appropriate. We propose a novel approach to multi-instance multi-label learning for RE, which jointly models all the instances of a pair of entities in text and all their labels using a graphical model with latent variables. Our model performs competitively on two difficult domains.
Relationship between relative interdialytic weight gain and serum leptin levels, nutrition, and inflammation in chronic hemodialysis patients.

INTRODUCTION Excessive relative interdialytic weight gain (RIDWG, %) is an important risk factor for long-term adverse cardiovascular outcomes in chronic hemodialysis (HD) patients. On the other hand, it may also be an index of good appetite and nutritional status. We aimed to assess the relationship between RIDWG and appetite, nutrition, inflammation parameters of chronic HD patients. METHODS 100 chronic anuric HD patients were enrolled in this prospective study between January 2013 and January 2014. Patients with hospitalization, major surgery, obvious infectious/inflammatory disease, end-stage liver disease, malignancies, and malabsorption syndromes were excluded. Patients were divided into 3 groups according to their RIDWG levels; group 1 = RIDWG < 3%, group 2 = RIDWG: 3 - 5%, and group 3 = RIDWG > 5%. RESULTS Group 3 patients were younger (p = 0.011) and had a lower body mass index (BMI) (p = 0.014). Nutrition and inflammation parameters including malnutrition inflammation score (MIS), serum albumin, prealbumin, triceps skinfold thickness, hs-CRP, and TNF-α ere not significantly different between the groups. Leptin and leptin/BMI ratio were significantly lower in group 3 (p = 0.001). RIDWG was negatively correlated with age (p = 0.001, r = -0.371), BMI (p = 0.001, r = -0.372), leptin (p = 0.001, r = -0.369), leptin/BMI (p = 0.001, r = -0.369). After adjustment for BMI in linear regression analyis, leptin/BMI remained significantly correlated with RIDWG (p = 0.024). CONCLUSION This study revealed that RIDWG was associated with younger age, lower BMI and dry weight, and lower serum leptin levels. More detailed studies are needed to validate and dissect the mechanisms of these findings.
Feline Leukemia Virus-associated Myelopathy in Cats

Feline leukemia virus (FeLV) infection is associated with distinct neoplastic, hematologic, and immunosuppressive diseases. Here we report on a novel neurologic syndrome in 16 cats infected with FeLV for more than 2 years. Clinical signs consisted of abnormal vocalization, hyperesthesia, and paresis progressing to paralysis. The clinical course of affected cats involved gradually progressive neurologic dysfunction invariably resulting in euthanasia. Microscopically, white-matter degeneration with dilation of myelin sheaths and swollen axons was identified in the spinal cord and brain stem of affected animals. Neither neoplastic nor hematologic diseases commonly associated with FeLV infection were present. Fungal and protozoal infection in one animal was suggestive of impaired immune competence. Immunohistochemical staining of affected tissues revealed consistent expression of FeLV p27 antigens in neurons, endothelial cells, and glial cells. Furthermore, proviral DNA was amplified from multiple sections of spinal cord as well as intestine, spleen, and lymph nodes. These findings suggest that in a proportion of chronically FeLV-infected cats, a virus evolved with cytopathic potential for cells in the central nervous system.
Calcific tendinitis of the shoulder

Abstract Calcific tendinitis is a common disease that predominantly affects individuals aged between 40 and 60 years. Women seem to be more affected than men. Various factors have been suggested to play a role in this condition, such as abnormal activity of the thyroid gland, metabolic diseases (e.g. diabetes), and genetic predisposition. Various etiological hypotheses have been advanced: the degenerative and multiphasic theories are the two most accredited ones. Clinically, calcific tendinitis is characterized by severe, disabling pain which occurs spontaneously, usually in the morning. There can be concomitant stiffness, giving rise to a frozen shoulder-like clinical picture. Conventional radiography of the shoulder is the most appropriate imaging approach. Most cases resolve spontaneously. Many conservative treatments have been reported in the literature, showing varying levels of evidence of efficacy. Arthroscopic surgery is the orthopedic specialist’s last option. It is to be noted that post-surgical pain can persist for many weeks after the operation. Finally, it is important not to forget the variant characterized by osteolytic involvement of the greater tuberosity, which has been associated with a worse clinical outcome, both after conservative treatment and after surgery.
An Analytical Model for Information Centric Internet of Things Networks in Opportunistic Scenarios

The availability of environmental monitoring data collected by Internet of Things networks can be essential for many critical processes, such as relief operations in disaster areas. The underlying communications infrastructure can be however severely compromised in these scenarios and therefore opportunistic approaches might be needed. Approaches based on information centric networks (ICN), where moving devices forward collected data, have been proposed for opportunistic scenarios but to date, the dynamics of the delivery process in ICNs remain poorly understood. In this paper, we build a family of Markovian models for the delivery process of ICNs in opportunistic scenarios, that allow us to derive the end-to-end delay distribution and the storage ratio in terms of the encounter rate of the moving devices. Furthermore, we investigate how prefetching mechanisms affect the delivery process compared to conventional ICNs. The proposed models are fully validated in a computer simulation environment and demonstrate that the utility of delivery with prefetching reaches its peak in a short time and then decreases at a high rate. Our Markovian models can provide both the insight and quantitative estimations that are needed to design practical ICNs in opportunistic scenarios.
Design and implementation of a low cost, pump-based, depth control of a small robotic fish

Recently, there has been growing interest in biomimetic underwater vehicles. To exploit the full workspace of this kind of vehicles, depth control is needed and plays a critical role. Although depth control for large vehicles such as submarines has been addressed, this issue for low-cost, small-scale underwater vehicles has not received attention. In this paper, the depth control of a small robotic fish is studied, and implemented with the use of a small dc pump. The depth system dynamics are developed and limitations rising from the low-cost, small-scale actuators and sensors are described. A controller with limited feedback is designed, implemented and validated both by simulations and experiments. It is expected that this controller will add an important dimension to depth control of low-cost, energy-efficient small underwater vehicles.
Semiflows generated by Lipschitz perturbations of non-densely defined operators

A variety of problems in differential equations ((abstract) functional differential equations, age-dependent population models (with and without delay), evolution equations with boundary conditions e.g.) can be written as semilinear Cauchy problems with a Lipschitz perturbation of a closed linear operator which is not non-densely defined but satisfies the estimates of the Hille&Yosida theorem. A natural generalized notion of solution is provided by the integral solutions in the sense of Da Prato&Sinestrari. Ideas from ‘integrated semigroup’ theory yield a variation of constants formula which allows to transform the integral solutions of the evolution equation to solutions of an abstract semilinear Volterra integral equation. The latter can be used to find integral solutions to the Cauchy problem; moreover one finds sufficient and necessary conditions for the (forward) invariance of closed convex sets under the solution flow. The solution flow can be shown to form a dynamical system. Conditions for the regularity of the flow in time and initial state are derived. The steady states of the flow are characterized and sufficient conditions for local stability and instability are found. Finally the problems mentioned at the beginning are fitted into the general framework.
Diagnostic Value of Procalcitonin in ANCA-Associated Vasculitis (AAV) to Differentiate Between Disease Activity, Infection and Drug Hypersensitivity

Objective: Procalcitonin (PCT) is considered to be a specific marker for severe bacterial infections and sepsis. Elevated PCT levels have been reported in active autoimmune diseases without infection. The aim of this study was to assess the diagnostic value of PCT serum levels in ANCA-associated vasculitis (AAV) patients with respect to infection, disease activity and drug fever using a high sensitive PCT detection method. Methods: In 53 AAV patients with elevated C-reactive protein (CRP) PCT was determined by the Thermo Scientific BRAHMS PCT sensitive KRYPTOR assay. Patients underwent standardized diagnostic procedures for evaluation of disease activity and infection. Results: 53 patients with AAV and elevated CRP (7.7±6.9 mg/dl, PCT 0.34±1.02 ng/ml) were assessed, 10 had infection with elevated CRP levels of 11.2±10.2 mg/dl and PCT levels of 1.06±2.07 ng/dl. 43 patients had no evidence of infection, 36 of them were presented with AAV with normal or only slightly positive PCT levels in active disease (n=36) (PCT 0.06±0.06 ng/ml). 7 patients had increased PCT levels due to azathioprine hypersensitivity (0.76±1.01 ng/ml). For discrimination between infection and vasculitis activity PCT was more useful than CRP with the best cut-off at 0.1 ng/ml (sensitivity 60%, specificity 92%). Conclusion: In contrast to previous studies using semiquantitative PCT assays, the KRYPTOR performs better with respect to discrimination of infection from active AAV. In all patients assessed with active AAV (and without infection) PCT levels remained below the PCT reference limit (0.5 ng/ml) for infections. Drug hypersensitivity seems to be an important differential diagnosis in the setting of elevated CRP and PCT in patients who receive azathioprine.
Monitoring equity in health and healthcare: a conceptual framework.

This paper aims at articulating a conceptual framework for monitoring equity in health and healthcare. The focus is on four main questions: What is health equity? What is monitoring? What are the essential components of a system for monitoring health equity? and Why monitor health equity? Monitoring equity in health and healthcare requires comparing indicators of health and its social determinants among social groups with different levels of underlying social advantage, i.e. groups who occupy different positions in a social hierarchy. A framework is presented for formulating the key questions, defining the social groups to be compared, and selecting the health indicators and measures of disparity that are fundamental to monitoring health equity. Although monitoring health equity is a scientific endeavour, its fundamental objective is guided by values; technical challenges should be addressed as part of a broader strategy to confront the political obstacles to greater equity.
Biocompatibility of subcutaneously implanted marine macromolecules cross-linked bio-composite scaffold for cartilage tissue engineering applications

Abstract There is an intense interest in developing innovative biomaterials which support the invasion and proliferation of living cells for potential applications in tissue engineering and regenerative medicine. Present study demonstrated the in vivo biocompatibility and toxicity of a macromolecules cross-linked biocomposite scaffold composed of hydroxyapatite, alginate, chitosan and fucoidan abbreviated as HACF. The in vivo biocompatibility and toxicity of HACF scaffold were tested by comparing them with those of a biocompatible surgical metal implant (SMI) in a subcutaneous rat model. Following the implantation, animals were sacrificed and the scaffolds were resected at 1st, 4th, and 8th weeks; the surrounding tissue along with the implant was removed to evaluate its biocompatibility. The effects of implanted biomaterial scaffolds on vital organ systems such as liver, kidney, etc., have been studied by hematology and serum biochemistry. The activities of pro-inflammatory marker enzymes such as COX, 5-LOX, 15-LOX, and NOS were normal in rats implanted with HACF scaffold. Hematological parameters, antioxidant and lipid peroxidation status were also found to be normal in implanted rats same as that of control and SMI. The modulatory effect of implanted scaffold over inflammatory and stress signaling cascades were confirmed by the normalized mRNA expressions of NF-κB, TNF-α and IL-6. The histopathological analysis of liver, kidney and tissue support our results. Taken together, these results demonstrated that HACF biocomposite scaffold signifies its suitability for further research as a scaffold material for cartilage tissue engineering applications.
Spitzer Mid-Infrared Spectroscopy of Infrared Luminous Galaxies at z ~ 2. III. Far-IR to Radio Properties and Optical Spectral Diagnostics

We present the FIR, millimeter, and radio photometry and optical and NIR spectroscopy of a sample of 48 z ∼ 1–3 Spitzer-selected ULIRGs with IRS MIR spectra. Our goals are to compute their bolometric emission and to determine both the presence and relative strength of their AGN and starburst components. We find that strong-PAH sources tend to have higher MIPS 160 μm and MAMBO 1.2 mm fluxes than weak-PAH sources. The depth of the 9.7 μm silicate feature does not affect MAMBO detectability. We fit the far-IR SEDs of our sample and find an average ⟨LIR⟩ ∼ 7 × 1012 L☉ for our z > 1.5 sources. Our spectral decomposition suggests that strong-PAH sources typically have ~20%-30% AGN fractions of LIR. The weak-PAH sources by contrast tend to have ≳70% AGN fractions, with a few sources having comparable contributions of AGN and starbursts. The optical line diagnostics support the presence of AGNs in the bulk of the weak-PAH sources. With one exception, our sources are narrow-line sources, show no obvious correspondence between the available optical extinction and the silicate feature depth, and, in two cases, show some evidence for outflows. Radio AGNs are present in both strong- and weak-PAH sources. This is supported by our sample’s FIR-to-radio ratios (q) being consistently below the average value of 2.34 for local star-forming galaxies. We use survival analysis to include the lower limits given by the radio-undetected sources, arriving at ⟨q⟩ = 2.07 ± 0.01 for our z > 1.5 sample. In total, radio and, where available, optical line diagnostics support the presence of AGNs in 57% of the z > 1.5 sources, independent of IR-based diagnostics. For higher z sources, the AGN luminosities alone are estimated to be >1012 L☉, which, supported by the available [O III] luminosities, implies that the bulk of our sources host obscured quasars.
Validation of Satellite Precipitation Estimates over the Congo Basin

This paper evaluates nine satellite rainfall products and the Global Precipitation Centre Climatology (GPCC) gauge dataset over the Congo basin. For the evaluation the reference dataset is a newly created, gridded gauge dataset based on a gauge network that is more complete than that of GPCC in recent years. It is termed NIC131-gridded. Gridding was achieved via a climatic reconstruction method based on principal components, so that reliable estimates of rainfall are available even in the data-sparse central basin. The satellite products were evaluated for two locations, the Congo basin and areas on its eastern and western periphery (termed the “east plus west” sector). The station density was notably higher in the latter region. Two time periods were also considered: 1983–94, when station density was relatively high, and 1998–2010, when station density was much lower than during the earlier period. Several products show excellent agreement with the NIC131-gridded reference dataset. These include CHIRPS2, PERSIANN-CDR, GPCP 2.3, TRMM 3B43, and, to a lesser extent, GPCC V7. RMSE for the period 1983–94 in the east plus west sector is on the order of 20 mm month−1 for GPCC V7 and 20–30 mm month−1 for the other products. The compares with 40–60 mm month−1 for the most poorly performing products, African Rainfall Climatology version 2 (ARCv2) and CMAP. Over the Congo basin, RMSE for those two products is about the same as in the east plus west sector but is on the order of 30–40 mm month−1 for the better-performing products. In all cases, the performance of the 10 products evaluated is notably poorer in recent years (1998–2010), when the station network is sparse, than during the period 1983–94, when the dense station network provides reliable estimates of rainfall. For the more recent period RMSE is on the order of 30–40 mm month−1 for the best-performing products in the east plus west sector but only slightly higher over the Congo basin. All products do reasonably well in reproducing the seasonal cycle and the latitudinal gradients of rainfall. Estimates of interannual variability show more scatter among the various products and are less reliable. Overall, the most important results of the study are to demonstrate the strong impact that actual gauge data have on the various products and the need to have access to such gauge data, in order to produce reliable rainfall estimates from satellites.
Learning whole upper body control with dynamic redundancy resolution in coupled associative radial basis function networks

We present a dynamical system approach to learning forward and inverse kinematics of a humanoid upper body in associative radial basis function networks. Coupling of arm kinematics via the torso joints is modeled by dynamically coupling two networks learning the direct inverse kinematics of both torso-arm chains separately. Dividing the upper body kinematics in two problems significantly reduces the number of samples required for learning. Redundancies of the inverse kinematics are represented by multi-stable dynamics of the associative networks and are resolved dynamically depending on the current system state. The model is exploited for task space tracking in a feedback control framework.
SpecialTime: Automatically Detecting Dialogue Acts from Speech to Support Parent-Child Interaction Therapy

Parent-child interaction therapy (PCIT) helps parents improve the quality of interaction with children who have behavior problems. The therapy trains parents to use effective dialogue acts when interacting with their children. Besides weekly coaching by therapists, the therapy relies on deliberate practice of skills by parents in their homes. We developed SpecialTime, a system that provides parents engaged in PCIT with automatic, real-time feedback on their dialogue act use. To do this, we first created a dataset of 6,022 parent dialogue acts, annotated by experts with dialogue act labels that therapists use to code parent speech. We then developed an algorithm that classifies the dialogue acts into 8 classes with an overall accuracy of 78%. To test the system in an actual clinical setting, we conducted a one month pilot study with four parents currently in therapy. The results suggest that automatic feedback on spoken dialogue acts is possible in PCIT, and that parents find the automatic feedback useful.