Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of California’s Breast Density Notification Legislation on Breast Cancer Screening

Purpose: Half of US states mandate women be notified if they have dense breasts on their mammogram, yet guidelines and data on supplemental screening modalities are limited. Breast density (BD) refers to the extent that breast tissue appears radiographically dense on mammograms. High BD reduces the sensitivity of screening mammography and increases breast cancer risk. The aim of this study was to determine the potential impact of California’s 2013 BD notification legislation on breast cancer screening patterns. Methods: We conducted a cohort study of women aged 40 to 74 years who were members of a large Northern California integrated health plan (approximately 3.9 million members) in 2011-2015. We calculated pre- and post-legislation rates of screening mammography and magnetic resonance imaging (MRI). We also examined whether women with dense breasts (defined as BI-RADS density c or d) had higher MRI rates than women with nondense breasts (defined as BI-RADS density a or b). Results: After adjustment for race/ethnicity, age, body mass index, medical facility, neighborhood median income, and cancer history, there was a relative 6.6% decrease (relative risk [RR] 0.934, confidence interval [CI] 0.92-0.95) in the rate of screening mammography, largely driven by a decrease among women <50 years. While infrequent, there was a relative 16% increase (RR 1.16, CI 1.07-1.25) in the rate of screening MRI, with the greatest increase among the youngest women. In the postlegislation period, women with extremely dense breasts (BI-RADS d) had 2.77 times (CI 1.93-3.95) the odds of a MRI within 9 months of a screening mammogram compared with women with nondense breasts (BI-RADS b). Conclusions: In this setting, MRI rates increased in the postlegislation period. In addition, women with higher BD were more likely to have supplementary MRI. The decrease in mammography rates seen primarily among younger women may have been due to changes in national screening guidelines.
Verbal Abuse by the Teacher and Child Adjustment From Kindergarten Through Grade 6

OBJECTIVES. Many adults mention past incidences of verbal abuse by the teacher as the most overwhelming negative experience in their lives. The present study examined (1) the course and stability of verbal abuse by the teacher from kindergarten through grade 4 and (2) the link between verbal abuse by the teacher and children's behavioral, emotional, and academic adjustment. DESIGN. Participants were 399 children (177 girls) who were assessed yearly over a period of 7 years, starting in kindergarten. Verbal abuse by the teacher, as well as acceptance versus rejection by the peer group from kindergarten through grade 4, were assessed through peer nomination. Child adjustment from kindergarten through grade 4 (antisocial behavior, attention problems, anxiety) was evaluated by the teacher. Child adjustment in early adolescence (delinquent behavior, depressive feelings, academic performance) was assessed by teacher evaluations and self-reports. RESULTS. The vast majority of children (∼85%) have almost 0 risk of becoming a target of verbal abuse by the teacher over the course of elementary school. However, a small minority of children (15%) seems to be at relatively high risk of verbal abuse by the teacher in kindergarten, and this risk increases even further over the course of elementary school. Boys, as well as children with high levels of early antisocial behavior and attention problems in kindergarten, are at high risk of verbal abuse by the teacher during elementary school. In turn, verbal abuse by the teacher is significantly related to subsequent delinquent behavior and academic difficulties in early adolescence, although this effect depends on child characteristics. CONCLUSIONS. Verbal abuse by the teacher seems to be a highly stable phenomenon for at-risk children. Children who are relatively well adjusted are at low risk of becoming the target of verbal abuse by the teacher. If they do, however, these children are the most vulnerable to subsequent developmental difficulties.
Delusions and hallucinations are associated with worse outcome in Alzheimer disease.

BACKGROUND Delusions and hallucinations are common in Alzheimer disease (AD) and there are conflicting reports regarding their ability to predict cognitive decline, functional decline, and institutionalization. According to all previous literature, they are not associated with mortality. OBJECTIVE To examine whether the presence of delusions or hallucinations has predictive value for important outcomes in AD. DESIGN, SETTING, AND PARTICIPANTS A total of 456 patients with AD at early stages (mean Folstein Mini-Mental State Examination [MMSE] score of 21 of 30 at entry) were recruited and followed up semiannually for up to 14 years (mean, 4.5 years) in 5 university-based AD centers in the United States and Europe. Using the Columbia University Scale for Psychopathology in AD (administered every 6 months, for a total of 3266 visit-assessments, average of 7.2 per patient), the presence of delusions and hallucinations was extracted and examined as time-dependent predictors in Cox models. The models controlled for cohort effect, recruitment center, informant status, sex, age, education, a comorbidity index, baseline cognitive and baseline functional performance, behavioral symptoms, and use of neuroleptics and cholinesterase inhibitors. MAIN OUTCOME MEASURES Cognitive (Columbia MMSE score of < or =20/57 [approximate Folstein MMSE score of < or =10/30]), functional (Blessed Dementia Rating Scale [parts I and II] score of > or =10), institutionalization equivalent index, and death. RESULTS During the full course of follow-up, 38% of patients reached the cognitive, 41% the functional, 54% the institutionalization, and 49% the mortality end point. Delusions were noted for 34% of patients at baseline and 70% at any evaluation. Their presence was associated with increased risk for cognitive (risk ratio [RR], 1.50; 95% confidence interval [CI], 1.07-2.08) and functional decline (RR, 1.41; 95% CI, 1.02-1.94). Hallucinations were present in 7% of patients at initial visit and in 33% at any visit. Their presence was associated with increased risk for cognitive decline (RR, 1.62; 95% CI, 1.06-2.47), functional decline (RR, 2.25; 95% CI, 1.54-2.27), institutionalization (RR, 1.60; 95% CI, 1.13-2.28), and death (RR, 1.49; 95% CI, 1.03-2.14). CONCLUSIONS Delusions and hallucinations are very common in AD and predict cognitive and functional decline. Presence of hallucinations is also associated with institutionalization and mortality.
Frictional anisotropy in nonmetallic crystals

A study is made of the effect of the crystallographic direction of sliding on the friction of the (001) surfaces of diamond, magnesium oxide and lithium fluoride crystals. The friction shows marked anisotropy and with all the crystals it is greatest in the <100> directions and least in the <110> directions. The degree and magnitude of the anisotropy is dependent upon the shape of the slider and the ease with which it penetrates the crystal surface. Sharp sliders increase the degree of brittle failure and this leads to deeper penetration and to the removal of more material during sliding. With these crystals the depth of penetration is greater in the <100> directions then in the <110> and it is this which is primarily responsible for the frictional anisotropy. An explanation of frictional anisotropy is proposed which is based on the difference in the magnitude and distribution of resolved shear stresses during sliding in various crystallographic directions. This analysis is used to predict the effect of crystallographic orientation on the frictional behaviour when a (110) surface of magnesium oxide replaces the cube (001) surface used in the other experiments. Mechanisms of deformation and fracture associated with the friction are described. Brittle behaviour predominates in diamond crystals and only cleavage cracks are observed. Appreciable plastic flow occurs in both magnesium oxide and lithium fluoride crystals. With these crystals the initial plastic deformation leads to dislocation interactions which result in cracking and fracture along the {110} planes. These interact with cleavage cracks on {100} planes which are produced by tensile stress and cause surface fragmentation and wear of the crystal. Plastic flow is the only mode of deformation observed on (001) lithium fluoride surfaces when a very smooth blunt slider is used. This causes ‘pile-up’ of material along <110> directions (as previously observed in copper crystals) but it does not produce any appreciable anisotropy in the friction.
Evidence that a C1q/C1qR system regulates monocyte-derived dendritic cell differentiation at the interface of innate and acquired immunity

Growing evidence shows that C1q modulates the growth and function of cells committed to the monocyte-derived dendritic cell (DC) lineage. Because C1q regulates both innate and acquired immune responses, we postulated that C1q modulates the transition from monocytes to DCs, i.e. the interface between innate and acquired immunity. Human peripheral blood monocytes cultured with soluble C1q and DC growth factors (granulocyte-macrophage colony-stimulating factor + Interleukin-4) failed to down-regulate monocyte-associated (CD14, CD16) and up-regulate DCassociated (CD83, CD86) markers. Impaired DC differentiation was not due to apoptosis; further analysis revealed the development of CD14hiCD11chiCD16 +/— cells that have previously been associated with both innate and acquired immunity. Monocyte—DC precursors expressed gC1qR, the receptor for globular heads of C1q, from the outset, while cC1qR, the receptor for the collagen tails of C1q, was expressed at low levels. Notably, the binding pattern of monoclonal antibodies specific to the globular heads of C1q indicated that C1q is bound to monocytes via globular heads, presumably through gC1qR. Moreover, gC1qR levels decreased, while cC1qR levels were dramatically amplified as monocytes differentiated into immature DC. Thus, specific C1q/C1q receptor (R) interactions may control the transition from the monocyte state (innate immunity) toward the professional antigen-presenting cell state (adaptive immunity).
On the thickness of soap films: an alternative to Frankel's law

The formation of soap films by vertical withdrawal from a bath is typically described by Frankel's law, which assumes rigid film ‘walls’ and shear-like dynamics. Since most soap films have interfaces that are not rigid, and as the flow in the withdrawal of thin free films is typically extensional, we reconsider the theory of soap film formation. By assuming extensional flow dominated by surface viscous stresses we find that the film thickness scales as the two-thirds power of the withdrawal speed U. This speed dependence is also predicted by Frankel's law; the difference lies in the origin of the viscous resistance which sets the pre-factor. When bulk viscous stresses are important the speed dependence can vary between U2/3 and U2.
Sclerosing encapsulating peritonitis: a case report

Sclerosing encapsulating peritonitis, a rare cause of bowel obstruction, was described as a complication associated with peritoneal dialysis which is much feared because of its severity. The authors report a case where radiological findings in association with clinical symptoms have allowed for a noninvasive diagnosis of sclerosing encapsulating peritonitis, emphasizing the high sensitivity and specificity of computed tomography to demonstrate the characteristic findings of such a condition.
Treatment of localized gingival recession using the free rotated papilla autograft combined with coronally advanced flap by conventional (macrosurgery) and surgery under magnification (microsurgical) technique: A comparative clinical study

Background: The aim of the present study was to evaluate and compare the conventional (macro-surgical) and microsurgical approach in performing the free rotated papilla autograft combined with coronally advanced flap surgery in treatment of localized gingival recession. Materials and Methods: A total of 20 sites from 10 systemically healthy patients were selected for the study. The selected sites were randomly divided into experimental site A and experimental site B by using the spilt mouth design. Conventional (macro-surgical) approach for site A and micro-surgery for site B was applied in performing the free rotated papilla autograft combined with coronally advanced flap. Recession depth (RD), recession width (RW) clinical attachment level (CAL.) and width of keratinized tissue (WKT.) were recorded at baseline, 3 months and 6 months post-operatively. Results: Both (macro- and microsurgery) groups showed significant clinical improvement in all the parameters (RD, RW, CAL and WKT). However, on comparing both the groups, these parameters did not reach statistical significance. Conclusion: Both the surgical procedures were equally effective in treatment of localized gingival recession by the free rotated papilla autograft technique combined with coronally advanced flap. However, surgery under magnification (microsurgery) may be clinically better than conventional surgery in terms of less post-operative pain and discomfort experienced by patients at the microsurgical site.
Browsing and keyword-based profiles: a cautionary tale

In the research presented, adaptive user profiles are used to rate Web pages with respect to possible user interest. The user profiles consist of weighted keywords and the adaptation is based on the Hebbian Learning Model with direct user feedback. A user study was conducted to determine if the system would "learn" over a series of five sessions when there was no explicit task other than to browse. The results are analogous to reading the news, i.e., it is not possible to predict what pages a user will read if there is no explicit task. We suggest that a shift away from content to document style (genre) and other user characteristics may be more effective.
Numerical Description of Dilute Particle-Laden FLows by a Quadrature-Based Moment Method

The numerical simulation of gas-particle flows is divided into two families of methods. In Euler-Lagrange methods individual particle trajectories are computed, whereas in Euler-Euler methods particles are characterized by statistical descriptors. Lagrangian methods are very precise but their computational cost increases with instationarity and particle volume fraction. In Eulerian methods (also called moment methods) the particlephase computational cost is comparable to that of the fluid phase but requires strong simplifications. Existing Eulerian models consider unimodal or close-to-equilibrium particle velocity distributions and then fail when the actual distribution is far from equilibrium. Quadrature-based Eulerian methods introduce a new reconstruction of the velocity distribution, written as a sum of delta functions in phase space constrained to give the right values for selected low-order moments. Two of these quadrature-based Eulerian methods, differing by their reconstruction algorithm, are the focus of this work. Computational results for two academic cases (crossing jets, Taylor-Green flow) are compared to those of a Lagrangian method (considered as the reference solution) and of an existing second-order moment method. With the quadrature-based Eulerian methods, significant qualitative improvement is noticed compared to the second-order moment method in the two test cases.
Patient complaints and malpractice risk.

CONTEXT A small number of physicians experience a disproportionate share of malpractice claims and expenses. If malpractice risk is related in large measure to factors such as patient dissatisfaction with interpersonal behaviors, care and treatment, and access, it might be possible to monitor physicians' risk of being sued. OBJECTIVE To examine the association between physicians' patient complaint records and their risk management experiences. DESIGN, SETTING, AND PARTICIPANTS Retrospective longitudinal cohort study of 645 general and specialist physicians in a large US medical group between January 1992 and March 1998, accounting for 2546 physician-years of care. MAIN OUTCOME MEASURES Computerized records of all unsolicited patient complaints were recorded by the medical center's patient affairs office, coded to characterize the nature of the problem and alleged offender, and compared with each physician's risk management records for the same period. RESULTS Both patient complaints and risk management events were higher for surgeons than nonsurgeons. Specifically, 137 (32%) of the 426 nonsurgeons had at least 1 risk management file compared with nearly two thirds (137 [63%] of 219) of all surgeons (chi2(1)= 54.7, P<. 001). Both complaint and risk management data were positively correlated with physicians' volume of clinical activity. Logistic regression revealed that risk management file openings, file openings with expenditures, and lawsuits were significantly related to total numbers of patient complaints, even when data were adjusted for clinical activity. Predictive concordance of specialty group, complaint count, clinical activity, and sex for risk management file openings was 84%; file openings with expenditures, 83%; lawsuits, 81%; and multiple lawsuits, 87%. CONCLUSIONS Unsolicited patient complaints captured and recorded by a medical group are positively associated with physicians' risk management experiences.
Multichannel speech dereverberation based on convolutive nonnegative tensor factorization for ASR applications

Room reverberation is a primary cause of failure in distant speech recognition (DSR) systems. In this study, we present a multichannel spectrum enhancement method for reverberant speech recognition, which is an extension of a single-channel dereverberation algorithm based on convolutive nonnegative matrix factorization (NMF). The generalization to a multichannel scenario is shown to be a special case of convolutive nonnegative tensor factorization (NTF). The presented algorithm integrates information from across different channels in the magnitude short time Fourier transform (STFT) domain. By doing so, it eliminates any limitations on the array geometry or a need for information concerning the source location, making the algorithm particularly suitable for distributed microphone arrays. Experiments are performed on speech data using actual room impulse responses from AIR database. Relative WER improvements using a clean-trained ASR system vary from +7.1% to +30.1% based on the number of channels and the source to microphone distances (1 to 3 meters).
Does Exposure to a Radiofrequency Electromagnetic Field Modify Thermal Preference in Juvenile Rats?

Some studies have shown that people living near a mobile phone base station may report sleep disturbances and discomfort. Using a rat model, we have previously shown that chronic exposure to a low-intensity radiofrequency electromagnetic field (RF-EMF) was associated with paradoxical sleep (PS) fragmentation and greater vasomotor tone in the tail. Here, we sought to establish whether sleep disturbances might result from the disturbance of thermoregulatory processes by a RF-EMF. We recorded thermal preference and sleep stage distribution in 18 young male Wistar rats. Nine animals were exposed to a low-intensity RF-EMF (900 MHz, 1 V.m−1) for five weeks and nine served as non-exposed controls. Thermal preference was assessed in an experimental chamber comprising three interconnected compartments, in which the air temperatures (Ta) were set to 24°C, 28°C and 31°C. Sleep and tail skin temperature were also recorded. Our results indicated that relative to control group, exposure to RF-EMF at 31°C was associated with a significantly lower tail skin temperature (−1.6°C) which confirmed previous data. During the light period, the exposed group preferred to sleep at Ta = 31°C and the controls preferred Ta = 28°C. The mean sleep duration in exposed group was significantly greater (by 15.5%) than in control group (due in turn to a significantly greater amount of slow wave sleep (SWS, +14.6%). Similarly, frequency of SWS was greater in exposed group (by 4.9 episodes.h−1). The PS did not differ significantly between the two groups. During the dark period, there were no significant intergroup differences. We conclude that RF-EMF exposure induced a shift in thermal preference towards higher temperatures. The shift in preferred temperature might result from a cold thermal sensation. The change in sleep stage distribution may involve signals from thermoreceptors in the skin. Modulation of SWS may be a protective adaptation in response to RF-EMF exposure.
Radiofrequency Catheter Ablation of Ventricular Premature Complexes

Frequent ventricular premature complexes (VPC) can result in left ventricular dysfunction. Several case reports have found this association and reversal with radiofrequency ablation [1-4]. Other peculiar problems reported to be due to VPCs and relieved by radiofrequency ablation include intermittent claudication [5], chronic cough with cough syncope [6,7] and dysphagia [8], mostly by the same group of authors. An interesting case in which radiofrequency catheter ablation of VPCs resulted in improvement of left ventricular function in a non-responder to cardiac resynchronization therapy has also been reported [9].
Osteoporosis after Stroke: A Review of the Causes and Potential Treatments

Osteoporosis is a known consequence of stroke, associated with an increased incidence of fractures, mainly of the hip, leading to further disability. The pattern of bone loss seen in stroke patients is different from that usually encountered with postmenopausal osteoporosis, since it is limited to the paretic side and more evident in the upper extremities. Several factors appear to have an influence on bone mass in stroke patients, such as the degree of paresis, gait disability and the duration of immobilization. The pathogenesis of osteoporosis after stroke remains unclear. Paresis, reduced mobility and reduced bone load seem to play a major role. Other factors such as nutritional and iatrogenic ones may also play an important part. In this paper, the clinical evidence, pathophysiology and possible treatments of poststroke osteoporosis will be reviewed.
Evidence Basis for Ultrasound-Guided Block Characteristics: Onset, Quality, and Duration

Background and Objectives: This systematic review summarizes existing evidence for superior onset, quality, and duration of block for ultrasound (US) guidance versus other techniques for nerve localization. Methods: MEDLINE was systematically searched from 1966 to September 2009 for randomized controlled trials (RCTs) comparing US guidance to another technique for peripheral nerve blocks. Results: Sixteen RCTs were identified for upper-extremity peripheral nerve blocks and 8 for lower extremity. Jadad scores for quality of RCT ranged from 1 to 5, with a median of 2. For upper-extremity blocks, 9 (60%) of 15 RCTs reported faster onset of block, 4 (25%) of 16 reported better quality of block, and 1 (17%) of 6 reported longer duration of block with US. Only 1 RCT reported that US was inferior in any outcome. For lower-extremity blocks, 5 (71%) of 7 RCTs reported faster onset, 5 (63%) of 8 reported better quality, and none of 3 RCTs reported longer duration of blocks. No RCTs reported that US was inferior in any outcome. Conclusions: There is level 1b evidence to make a grade A recommendation that US guidance provides a modest improvement in block onset and quality of peripheral nerve blocks. Ultrasound is rarely inferior to other techniques.