Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence of non-adherence to antihypertensive pharmacotherapy and associated factors.

OBJECTIVE The aim of the study was to determine the prevalence of non-adherence to antihypertensive drug treatment and its association with factors bio-socio-economic and welfare. METHOD It was a descriptive, cross-sectional study, performed with 422 hypertensive individuals. Data were collected through home interviews, conducted between December 2011 and March 2012. RESULTS The results showed that the respondents were mostly female, married, elderly, low income and little time of diagnosis. Were considered non adherent to medication 42.65% of participants. Non-Caucasian hypertensive patients, with fewer than eight years of schooling, who did not regularly attend doctor's appointments, took more than two anti-hypertensive medications and did not have private health insurance, showed higher likelihood of not complying with the drug treatment. CONCLUSION These findings suggest that hypertensive patients with unfavorable socioeconomic characteristics and difficulty of access to the service require different interventions in order to encourage them to adhere to medication treatment.
Electrochemical biosensor development for detection of L-Dopa levels in plasma during Parkinson illness

In this paper, the development of a new electrochemical biosensor for L-Dopa detection is described. The biosensor is built from home made screen printed electrodes with mushroom tyrosinase immobilized in a photo-crosslinkable polymeric gel on the working electrode. Concentrations of L-Dopa and other catechols are proved to be detected in the range of 5times10-7 M to 1times10-5 M. Although sensitivity needs to be improved for real application in plasma samples, the device appears promising as a way to evaluate L-Dopa levels during medication with this drug in Parkinson illness.
Technology use, adoption and behavior in older adults: Results from the iStoppFalls project

ABSTRACT Technology use is a common constituent of modern life. However, little is known about older adults’ use of technology. This article presents a subset of data collected via the technology deployed in the iStoppFalls randomized control trial. The primary focus lies on questions about digital device/Internet use, ownership, length, and frequency as well as social networking. Data was collected from participants aged 65 years or older. Seventy-eight participants completed a specifically developed technology survey as part of the baseline assessment. Results showed that the majority of subjects owned a computer with men being its main user. Participants used technological devices on a daily basis for more than 1 year. The main reason for using technology was e-mail communication, search engines, text processing, and online shopping. Only a few participants used social network applications, with Google+ and Facebook being the most popular ones. Future work should consider an in-depth qualitative approach to further increase understanding of technology use in older adults.
Effect of Individualistic and Collectivistic Values on Total Role Stress Among the Government Officers of Nepal

Stress is the psycho-biological construct. Stress creates from the personal behavior and their surrounding environment. Social relationship and organizational environment determines the level of stress among the employee. The study was going to explore the interrelationship between the individual value and collective value with role stress among the Nepal government officer. The study had adopted the simple random sampling to select the respondents. A total 284 government employees from technical and non-technical sectors were selected. Data was taken from the three strata: 1st class, 2nd class and 3rd class officers. The findings showed the significant relationship between the individual and collective values. Mean of individual value was higher than the collective value but the role stress was higher among the officer who took the collective value very much than individual value. Similarly, the non-technical officers felt higher level of stress than the technical officers.
Enhanced Photocatalytic Activity of Ag Doped ZnO Nanorods for Degradation of an Azo Dye

In this study, Ag‐ZnO nanophotocatalyst has been synthesized through microemulsion technique and the effect of silver modification on ZnO nanorods has been evaluated. The photocatalytic activity of nanocatalyst was examined by degradation of Acid Yellow 23 (AY23) as a model of mono azo dye under UV illumination. Ag‐ZnO catalyst was characterized by X‐ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X‐ray spectroscopy (EDXS) and diffuse reflectance spectroscopy (DRS) analysis. The degradation of AY23 was studied under different operational parameters. Results show that the photocatalytic reaction followed the pseudo‐first‐order kinetic. The highest photocatalytic degradation of 20 mg/L AY23 dye solution under UV irradiation (light intensity = 50 W/m2 , [Ag‐ZnO]0 = 400 mg/L with 2 wt% Ag doped ZnO, calcined at 450 °C) was about 93.3% during 30 minutes of reaction that shows an enhancement in comparison to pure ZnO which was 65.48%.
The effect of addition of linoleic acid on food intake regulation in linoleic acid tasters and linoleic acid non-tasters

In a randomised, single blind, placebo-controlled crossover design study, we investigated whether healthy, non-smoking, dietary unrestrained women (n 24), divided into linoleic acid tasters (LAT, n 14) and linoleic acid non-tasters (LANT, n 10), differed in food intake regulation when linoleic acid was added to ice creams. The determination of subjects as LAT or LANT was done using a 10μM-linoleic acid solution. The ice creams were characterised by the subjects and a taste perception test using the triangle test was conducted three times. Food intake and appetite were measured using the universal eating monitor. LAT and LANT did not differ in characterisation or in taste perception of the ice creams, even though LAT were able to increase their ability to discriminate between the ice cream with linoleic acid from the one containing oleic acid. No effect of LAT status or type of ice cream was found for hedonic value of the ice creams. Linoleic acid taster status did affect food intake regulation. For LAT, but not LANT, the amount eaten was a function of Δsatiety. Subjects ate by weight of food and not by energy content. In conclusion, differences in food intake regulation were seen between LAT and LANT, in that the amount eaten by LAT was a function of Δsatiety, but was not for LANT.
A novel method of comparing mating success and survival reveals similar sexual and viability selection for mobility traits in female tree crickets

The relationship between sexual and viability selection in females is necessarily different than that in males, as investment in sexual traits potentially comes at the expense of both fecundity and survival. Accordingly, females do not usually invest in sexually selected traits. However, direct benefits obtained from mating, such as nuptial gifts, may encourage competition among females and subsidize investment into sexually selected traits. We compared sexual and viability selection on female tree crickets Oecanthus nigricornis, a species where females mate frequently to obtain nuptial gifts and sexual selection on females is likely. If male choice determines female mating success in this species, we expect sexual selection for fecundity traits, as males of many species prefer more fecund females. Alternatively, intrasexual scramble or combat competition on females may select for larger jumping legs or wider heads (respectively). We estimated mating success in wild caught crickets using microsatellite analysis of stored sperm and estimated relative viability by comparing surviving female O. nigricornis to those captured by a common wasp predator. In support of the scramble competition hypothesis, we found sexual selection for females with larger hind legs and narrower heads. We also found stabilizing viability selection for intermediate head width and hind leg size. As predicted, traits under viability and sexual selection were very similar, and the direction of that selection was not opposing. However, because the shape of sexual and viability selection differs, these episodes of selection may favour slightly different trait sizes.
Caffeine Suppresses Apoptosis of Bladder Cancer RT4 Cells in Response to Ionizing Radiation by Inhibiting Ataxia Telangiectasia Mutated-Chk2-p53 Axis

Background: Caffeine suppresses ataxia telangiectasia and Rad3 related and ataxia telangiectasia mutated (ATM) activities; ATM is the major kinase for DNA damage detection. This study aimed to investigate the effects of caffeine on DNA damage responses in cells from the bladder cancer cell line RT4 those were exposed to ionizing radiation (IR). Methods: Immunofluorescent staining was performed to investigate changes in the proteins involved in DNA damage responses with or without caffeine. A mouse xenograft model was used to study the effects of caffeine on the DNA damage responses. Western blotting was used to investigate the effects of caffeine pretreatment on the ATM-Chk2-p53-Puma axis, while real-time polymerase chain reaction (RT-PCR) assessed changes in messenger RNA levels of p53 and downstream targets responding to IR. Finally, terminal deoxynucleotidyl transferase-dUTP nick end labeling assay. Western blotting and colony formation assay were used to measure the effects of caffeine on radiation-related apoptosis. All of the data were analyzed with a two-tailed Student's t-test. Results: Immunofluorescent staining showed that caffeine pretreatment profoundly suppressed the formation of &ggr;H2AXand p53-binding protein 1 foci in RT4 cells in response to irradiation. Cellular and animal experiments suggested that this suppression was mediated by suppression of the ATM-Chk2-p53-Puma DNA damage-signaling axis. RT-PCR indicated caffeine also attenuated transactivation of p53 and p53-inducible genes. The colony formation assay revealed that caffeine displayed radioprotective effects on RT4 cells in response to low-dose radiation compared to the radiosensitization effects on T24 cells. Conclusion: Caffeine may inhibit IR-related apoptosis of bladder cancer RT4 cells by suppressing activation of the ATM-Chk2-p53-Puma axis.
A Double‐Blind, Randomized, Placebo‐Controlled Trial of Macrolide in the Treatment of Chronic Rhinosinusitis

Objectives: The antiinflammatory effect of macrolide antibiotics has been well‐established, as has their role in the treatment of certain disorders of chronic airway inflammation. Several studies have suggested that long‐term, low‐dose macrolides may be efficacious in the treatment of chronic rhinosinusitis; however, these studies have lacked a control group. To date, this effect has not been tested in a randomized, placebo‐controlled study.
Rapidly labeled, polyribosome-associated RNA having the properties of histone messenger.

Histone synthesis and DNA replication (S phase) begin simultaneously in the HeLa cell life cycle. While these macromolecules are made, the cytoplasm contains a class of small polyribosomes which are absent in postmitotic (G,) cells and which disappear following exposure to cytosine arabinoside, an effective inhibitor of both DNA and histone synthesis. These polyribosomes incorporate a relative excess of lysine over tryptophan into their nascent polypeptides, supporting the hypothesis that they are the cytoplasmic site of histone synthesis. ' The present report describes: (a) the isolation of both histone-like polypeptides and 7-9S RNA species from these polyribosomes, and (b) the relationship between this 7-9S RNA and histone synthesis with specific reference to the possibility that it is messenger RNA.2 Materials and Methods. -IMost of the techniques used in the present work have been described in previous publications. These include maintenance of HeLa S3 cells in suspension culture,3 preparation of cytoplasmic polyribosomes with the detergent Nonidet P40 (NP40),4 analysis of polyribosomes in sucrose gradients,5 and extraction of histones and their separation into different electrophoretic groups on acrylamide gels. ' Cell synchronization: Although cells were usually synchronized by selective detachment of mitotic cells from monolayers,3 such populations become asynchronous late in the DNA-synthetic (S) and premitotic (G2) phases of the cell life cycle. For studies at those times, cells were synchronized by treatment in suspension with 2 mM thymidine6 for 16 hours, resuspension in fresh medium for 8 hours, followed by a second exposure to the drug for 16 hours. After a second resuspension in fresh medium, 90 per cent of the cells divided within 9 to 12 hours. Identification of polyribosome-associated polypeptides: To label nascent polypeptides with nearly equivalent amounts of radioactivity from each amino acid, 108 S-phase cells, resuspended in 10 ml of tryptophan, lysine, and serum-free growth medium,3 were incubated for one minute with 50,c C'4-lysine and 500 ,uc H3tryptophan. Cytoplasmic extracts were prepared with NP40,4 centrifuged through sucrose gradients, and analyzed for optical density at 260 mu and for acid-precipitable radioactivity.3 Appropriate fractions from the gradients were pooled, and polyribosomes were pelleted at 104,000 X g for one hour. Nascent polypeptides were released by treatment with 100 Mg/ml of ribonuclease at 37°C . 7 The samples were dissolved in 1% sodium dodecyl sulfate (SDS), 0.5 M urea, 0.1% 2-mercaptoethanol (ME); dialyzed against 0.1% SDS, 0.1% ME in 0.01 11 phosphate at pH 7.4; and electrophoresed On 7.5% acrylamide gels. ' G,and S-phase cells pretreated for one hour with 40 ug/ml cytosine arabinoside were similarly processed. Analysis of rapidly labeled, polyribosom.e-associated RNA: Synchronized cells at
Spontaneous prelabor unscarred uterine rupture in primigravida : a case report and review of literature

Spontaneous uterine rupture (SUR), a public health problem in developing countries, is a rare but hazardous obstetric complication with significant maternal and fetal morbidity and mortality. Cases of rupture are more likely to occur in a scarred uterus, usually after a previous caesarean delivery. Spontaneous unscarred uterus rupture (SUUR) in primigravid women is usually unexpected and extremely rare. Risk factors for SUUR include high parity, placental abnormalities, and uterine anomaly. Hereby, we presented a case of spontaneous unscarred uterus rupture during her pregnancy of 36 weeks +2 days in a primigravid woman without apparent causes. We then performed literature review covering similar cases to further remind physicians of the possibility of SUUR.
The Role of Domain and Gender-Specific Provisions of Social Relations in Adherence to a Prescribed Exercise Regimen

The present study investigated the role of domain-specific combinations of social support provisions in adherence to a prescribed exercise regimen. Research participants were middle-aged, sedentary, males and females (N = 85). Separate discriminant function analyses for males and females revealed that among females, the social provisions of guidance and reassurance of worth significantly discriminated adherers and nonadherers. The two provisions of social integration and guidance significantly discriminated adherers and nonadherers among males. Results are discussed with reference to the importance of social provisions in exercise settings, male and female differences, and the implications of social support interventions for enhancing exercise compliance.
A deep convolutional neural network for bleeding detection in Wireless Capsule Endoscopy images

Wireless Capsule Endoscopy (WCE) is a standard non-invasive modality for small bowel examination. Recently, the development of computer-aided diagnosis (CAD) systems for gastrointestinal (GI) bleeding detection in WCE image videos has become an active research area with the goal of relieving the workload of physicians. Existing methods based primarily on handcrafted features usually give insufficient accuracy for bleeding detection, due to their limited capability of feature representation. In this paper, we present a new automatic bleeding detection strategy based on a deep convolutional neural network and evaluate our method on an expanded dataset of 10,000 WCE images. Experimental results with an increase of around 2 percentage points in the Fi score demonstrate that our method outperforms the state-of-the-art approaches in WCE bleeding detection. The achieved Fi score is of up to 0.9955.
Mechanisms of Tumor and Viral Immune Escape from Natural Killer Cell-Mediated Surveillance

Human natural killer (NK) cells recognize and efficiently eliminate MHC class I low or negative malignant targets and virally infected host cells, without requirement for prior sensitization. However, viruses and various tumor cells display elaborate adaptations to evade and overcome immunosurveillance. The current review focuses on escape mechanisms of viruses and malignantly transformed ‘stressed’ cells to evade from NK cell cytotoxicity. A general overview of recent clinical studies using allogeneic donor NK cells is given, summarizing first data about a possible benefit for patients suffering from high-risk leukemia and solid tumors. Finally, the review discusses the future perspectives and hypotheses aiming to improve therapeutic NK cell strategies against tumor immune escape mechanisms.
Influencing Factors of Self-esteem and job stress on Teacher Efficacy for Childcare Teacher

Abstract The purpose of this study is to explore degree of childcare teacher’s teacher efficacy and the factors influencing of self-esteem and job stress on teacher efficacy of those surveyed. A total of 280 childcare teacher in G do were surveyed. All of this data is analyzed by using t-test, ANOVA, Pearson's correlation coefficients, multiple regression analysis with SPSS WIN/18.0. Teacher Efficacy according to general characteristics of those surveyed revealed significant difference in age, work experience, position, class age, and child parenting experience. Regression analysis showed 11.7% of variance in childcare teacher’s teacher efficacy can by experience of dating with self-esteem and job stress. The fallow-up survey about various factors influencing childcare teacher’s teacher efficacy is needed and teacher efficacy increasing mediation way are required. Key Words : Childcare Teacher, Job Stress, Self-esteem, Teacher Efficacy 1. 서 론 1.1 연구의 필요성기혼여성들의 경제활동 참여가 지속적으로 증가하면서 자녀 양육에 대한 가정의 기능이 약화되고 상당한 부분을 유아교육기관에 의존하고 있어 영유아 보육을 위한 양질의 서비스가 강조되고 있다. 그러나 우리나라 보육서비스에 대한 만족도는 서비스를 이용하는 부모들의 기대에 못 미치고 있는 것으로 나타났고, 만족도 내용 측면에서 인적요소의 중요성이 강조되고 있었다[1]. 최근의 영유아들은 유아기관에서 지내는 시간이 과거에 비해 늘어나고 대부분이 보육교사와 함께 생활하기
Special Relativity in Reduced Power Algebras

Recently, [10,11], the Heisenberg Uncertainty relation and the No-Cloning property in Quantum Mechanics and Quantum Computation, respectively, have been extended to versions of Quantum Mechanics and Quantum Computation which are re-formulated using scalars in {\it reduced power algebras}, [2-9], instead of the usual real or complex scalars. Here, the Lorentz coordinate transformations, fundamental in Special Relativity, are extended to versions of Special Relativity that are similarly re-formulated in terms of scalars in reduced power algebras, instead of the usual real or complex scalars. The interest in such re-formulations of basic theories of Physics are due to a number of important reasons, [2-11]. Suffice to mention two of them : the difficult problem of so called "infinities in Physics" falls easily aside due to the presence of infinitesimal and infinitely large scalars in such reduced power algebras, and the issue of fundamental constants in physics, like Planck's $h$, or the velocity of light $c$, comes under a new focus which offers rather surprising alternatives.
Satisfaction in Whitewater Rafting: The Effects of Risk, Emotion Management and Personality

FOY, STEVEN R. W. , M.S., August 2012, Recreation Studies Satisfaction in Whitewater Rafting: The Effects of Risk, Emotion Management and Personality Director of Thesis: C. Bruce Martin. Successful adventure recreation often includes the emotional arousal offered by the thrill and risk of the activity. In the context of commercial adventure recreation, guest satisfaction is associated with many benefits for both guest and service provider. This study examines the effect of the characteristics and abilities of the whitewater raft guide on guest satisfaction levels. The study consisted of surveying the guides and guests associated with a single outfitter on the Ocoee River, a popular river for rafting in the southeastern United Sates. Regression analyses measured the effects of various guide attributes (i.e., risk propensity, personality, guide proficiency, and ability to provide for emotional arousal) on guest satisfaction. Guest satisfaction was most strongly related to those aspects of the trip and guide abilities that provided for the most thrilling and exciting experience. Guide-specific attributes, such as risk propensity and personality, proved to have minimal influence on guest satisfaction. This study is exploratory in nature, responds to a breadth of qualitative research, and highlights the need for more substantial research addressing the guide-guest interaction. Approved: _____________________________________________________________ C. Bruce Martin Assistant Professor of Recreation and Sport Pedagogy
Adolescent Bystander Behavior in the School and Online Environments and the Implications for Interventions Targeting Cyberbullying

ABSTRACT The aim of this study was to add to the emerging knowledge about the role of bystanders in cyberbullying. To differentiate online versus offline bystander behaviors, 292 Australian children (mean age = 15.2; female = 54.4%) reviewed hypothetical scenarios experimentally manipulated by bystander sex, relationship to target and perpetrator, and severity of bullying incident. In both environments, bystander helping behaviors were more likely when the target was a close friend, perceived harm to the target was high, and when bystanders were female. Bystanders also reported being less likely to approach teachers or publicly defend targets in online versus offline environments. This suggests programs designed to encourage positive bystander behaviors online can be similar to face-to-face approaches, but they need to recognize some aspects unique to the online environment.
Longer Exposure to Obesity, Slimmer Chance of College? Body Weight Trajectories, Non-Cognitive Skills, and College Completion

The NLSY97 data were used to explore the patterns of developmental trajectories of body weight in adolescence and how they affected the likelihood of college completion in young adulthood among 2,275 youths aged 13 and 14 in Wave 1. A strong weight trajectory gradient was found for rates of college completion. The study further explored the role of non-cognitive traits in the association between weight trajectories and college attainment. Non-cognitive traits were found to partially mediate the impact of certain weight trajectories on the likelihood of college completion. Some moderating effects of conscientiousness were also found. The findings from the gender and weight trajectory interaction terms showed that a stronger negative impact of weight trajectory on college completion is only observed for women in the late-teen-onset overweight group. This study highlights the importance of using a longitudinal weight measure and the role of non-cognitive traits in adolescent obesity research.