Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimized LTE Cell Planning With Varying Spatial and Temporal User Densities

Base station (BS) deployment in cellular networks is one of the fundamental problems in network design. This paper proposes a novel method for the cell planning problem for fourth-generation (4G) cellular networks using metaheuristic algorithms. In this approach, we aim to satisfy both cell coverage and capacity constraints simultaneously by formulating an optimization problem that captures practical planning aspects. The starting point of the planning process is defined through a dimensioning exercise that captures both coverage and capacity constraints. Afterward, we implement a metaheuristic algorithm based on swarm intelligence (e.g., particle swarm optimization or the recently proposed gray-wolf optimizer) to find suboptimal BS locations that satisfy both problem constraints in the area of interest, which can be divided into several subareas with different spatial user densities. Subsequently, an iterative approach is executed to eliminate eventual redundant BSs. We also perform Monte Carlo simulations to study the performance of the proposed scheme and compute the average number of users in outage. Next, the problems of green planning with regard to temporal traffic variation and planning with location constraints due to tight limits on electromagnetic radiations are addressed, using the proposed method. Finally, in our simulation results, we apply our proposed approach for different scenarios with different subareas and user distributions and show that the desired network quality-of-service (QoS) targets are always reached, even for large-scale problems.
Imprint and Fatigue Properties of Chemical Solution Derived Pb_1–-xLa_x(Zr_yTi_1–y)_1–x/4O_3 Thin Films

We have investigated the effect of oxygen vacancies on imprint and fatigue behavior of the PLZT thin films. It is found that the compensation of oxygen vacancies with various dopant concentrations and electrode structures is an important process parameter in determining the tendency to imprint and fatigue. In the case of PLZT thin films, the voltage shifts related to imprint are attributed to the trapping of electrons at ionic defect sites such as oxygen vacancies near the film/electrode interface, the magnitude of polarization, and concentration of defect-dipole complexes involving oxygen vacancies such as V′_Pb–V^••o. The strong dependence of fatigue rate on electrode material for PLZT thin films is due to the effect of the ferroelectric/electrode interaction on the pinning and/or unpinning rate involving the accumulation of oxygen vacancies near the film/electrode interface during fatigue cycling. By using RuO_2 as the top and/or bottom electrode instead of Pt, improved fatigue properties are obtained compared to Pt/PLZT/Pt capacitors. This is because a reduced accumulation of oxygen vacancies near the interface by the oxide electrode such as RuO_2 may reduce the electronic charge trapping and, consequently, lead to less domain wall pinning.
The role of pattern vision in the development ofcortico‐cortical connections

The development of cortico‐cortical connections was studied in kittens deprived of vision by binocular eyelid suture during the formation of axonal arbors and synaptogenesis, i.e. between the second postnatal week and the end of the third postnatal month. Axons originating in area 17 and terminating either in ipsilateral or contralateral visual areas were visualized with biocytin. In ipsilateral areas 17 and 18, distinct clusters of branches begin to form, distally from the injection, during the second half of the first postnatal month, independently of pattern vision. More proximal clusters differentiate during the second postnatal month, and this seems to involve elimination of exuberant axonal branches. In kittens deprived of vision for 3 or more months, beginning before natural eye opening, the distal clusters regress and the proximal ones fail to differentiate. In extrastriate areas, distinct clusters of branches have segregated by the end of the second postnatal month, independently of visual experience; however, in kittens deprived of vision for 2 or more months, one of the clusters was selectively eliminated. In contralateral areas 17 and 18, we found stunted terminal arbors in kittens continuously deprived of vision. This was already noticeable at the end of the first postnatal month. Apparently, in the absence of pattern vision, most axons undergo only limited growth and do not form their characteristic terminal columns. Many of these axons are subsequently eliminated. In contrast, 8 days of vision beginning at natural eye opening and followed by visual deprivation caused a nearly normal development of intrahemispheric and interhemispheric connections. In conclusion, pattern vision appears to validate connections at early stages of their development; this validation is necessary for their further growth and differentiation that can then continue autonomously.
Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

The amyloid precursor protein (APP) is a transmembrane protein expressed in several cell types. In the nervous system, APP is expressed by glial and neuronal cells, and several lines of evidence suggest that it plays a role in normal and pathological phenomena. To address the question of the actual function of APP in normal developing neurons, we undertook a study aimed at blocking APP expression using antisense oligonucleotides. Oligonucleotide internalization was achieved by linking them to a vector peptide that translocates through biological membranes. This original technique, which is very efficient and gives direct access to the cell cytosol and nucleus, allowed us to work with extracellular oligonucleotide concentrations between 40 and 200 nM. Internalization of antisense oligonucleotides overlapping the origin of translation resulted in a marked but transient decrease in APP neosynthesis that was not observed with the vector peptide alone, or with sense oligonucleotides. Although transient, the decrease in APP neosynthesis was sufficient to provoke a distinct decrease in axon and dendrite outgrowth by embryonic cortical neurons developing in vitro. The latter decrease was not accompanied by changes in the spreading of the cell bodies. A single exposure to coupled antisense oligonucleotides at the onset of the culture was sufficient to produce significant morphological effects 6, 18, and 24 h later, but by 42 h, there were no remaining significant morphologic changes. This report thus demonstrates that amyloid precursor protein plays an important function in the morphological differentiation of cortical neurons in primary culture.
Knowledge discovery and integration based on a novel neural network ensemble model

This article explores the utility of neural network ensembles in knowledge discovery and integration. A novel neural network ensemble model KBNNE (Knowledge-Based Neural Network Ensembles) integrating KDD (Knowledge Discovery in Database) techniques and neural network modeling algorithms by ¿parallel operations¿ is proposed. Through balancing the relative importance of knowledge learned by induction and deduction, KBNNE can avoid the knowledge loss and enhance the "transparency" of neural network models. The effectiveness of the proposed model is demonstrated through computer simulations on simple artificial problems and an actual modeling problem.
Career Progression and Formal Versus On-the-Job Training

We develop a dynamic discrete choice model of training choice, employment and wage growth, allowing for job mobility, in a world where wages depend on firm-worker matches, as well as experience and tenure and jobs take time to locate. We estimate this model on a large administrative panel data set which traces labour market transitions, mobility across firms and wages from the end of statutory schooling. We use the model to evaluate the life-cycle return to apprenticeship training and find that on average the costs outweigh the benefits; however for those who choose to train the returns are positive. We then use our model to consider the long-term lifecycle effects of two reforms: One is the introduction of an Earned Income Tax Credit in Germany, and the other is a reform to Unemployment Insurance. In both reforms we find very significant impacts of the policy on training choices and on the value of realised matches, demonstrating the importance of considering such longer term implications.
Maximum entropy model for punctuation annotation from speech

In this paper we develop a maximum-entropy based method for annotating spontaneous conversationalspeech with punc-tuation. The goal of this task is to make automatic transcriptions more readable by humans, and to render them into a form that is useful for subsequent natural language processing and discourse analysis. Our basic approach is to view the insertion of punctuation as a form of tagging, in which words are tagged with appropriate punctuation, and to apply a maximum entropy tagger that uses both lexical and prosodic features. We present experimental results on Switchboard data with both reference transcriptions and transcriptions produced by a speech recognition system
TcoF-DB v2: update of the database of human and mouse transcription co-factors and transcription factor interactions

Transcription factors (TFs) play a pivotal role in transcriptional regulation, making them crucial for cell survival and important biological functions. For the regulation of transcription, interactions of different regulatory proteins known as transcription co-factors (TcoFs) and TFs are essential in forming necessary protein complexes. Although TcoFs themselves do not bind DNA directly, their influence on transcriptional regulation and initiation, although indirect, has been shown to be significant, with the functionality of TFs strongly influenced by the presence of TcoFs. In the TcoF-DB v2 database, we collect information on TcoFs. In this article, we describe updates and improvements implemented in TcoF-DB v2. TcoF-DB v2 provides several new features that enables exploration of the roles of TcoFs. The content of the database has significantly expanded, and is enriched with information from Gene Ontology, biological pathways, diseases and molecular signatures. TcoF-DB v2 now includes many more TFs; has substantially increased the number of human TcoFs to 958, and now includes information on mouse (418 new TcoFs). TcoF-DB v2 enables the exploration of information on TcoFs and allows investigations into their influence on transcriptional regulation in humans and mice. TcoF-DB v2 can be accessed at http://tcofdb.org/.
Segmentation of glides with tonal alignment as reference

This paper reports an attempt to determine the segmentation of glides using existing knowledge about tonal alignment as reference. It is found that the likely onset of a glide is much earlier than what is acoustically the most obvious, i.e., the point where the formants reach their extremes. It is further found that there is indication that the point of formant extremes may in fact be the point of glide release.
Speaker localization using excitation source information in speech

This paper presents the results of simulation and real room studies for localization of a moving speaker using information about the excitation source of speech production. The first step in localization is the estimation of time-delay from speech collected by a pair of microphones. Methods for time-delay estimation generally use spectral features that correspond mostly to the shape of vocal tract during speech production. Spectral features are affected by degradations due to noise and reverberation. This paper proposes a method for localizing a speaker using features that arise from the excitation source during speech production. Experiments were conducted by simulating different noise and reverberation conditions to compare the performance of the time-delay estimation and source localization using the proposed method with the results obtained using the spectrum-based generalized cross correlation (GCC) methods. The results show that the proposed method shows lower number of discrepancies in the estimated time-delays. The bias, variance and the root mean square error (RMSE) of the proposed method is consistently equal or less than the GCC methods. The location of a moving speaker estimated using the time-delays obtained by the proposed method are closer to the actual values, than those obtained by the GCC method.
A Prospective Study of Positive Early-Life Psychosocial Factors and Favorable Cardiovascular Risk in Adulthood

Background— The American Heart Association’s national goals for cardiovascular health promotion emphasize that cardiovascular risk originates early in life, but little is known about childhood factors that may increase the likelihood of having a favorable cardiovascular risk (FCR) in adulthood. We examined the prospective association between positive childhood factors and the likelihood of midlife FCR. We also considered pathways through which childhood factors may influence FCR. Methods and Results— We studied 415 adults (mean age=42.2 years) of the Collaborative Perinatal Project, a national cohort initiated in 1959 to 1966. We examined 3 positive childhood factors assessed at age 7 years: attention regulation (ability to stay focused), cognitive ability, and positive home environment. Of these adults, 10.6% had FCR in midlife. Adjusting for demographics and childhood cardiovascular health, a 1-unit increase in childhood attention regulation, cognitive ability, and positive home environment was associated with 2.4 (95% confidence interval, 1.1–4.7), 1.8 (95% confidence interval, 1.1–2.9), and 1.3 (95% confidence interval, 1.1–1.6) higher respective odds of having midlife FCR. The association with childhood attention regulation was maintained when accounting for adulthood factors; education and diet in part explained the associations with childhood cognitive ability and home environment. The effect of each attribute was additive as those with high levels of each childhood factor had 4.3 higher odds (95% confidence interval, 1.01–18.2) of midlife FCR in comparison with those low in all factors. Conclusions— Positive childhood psychosocial factors may promote healthy adult cardiovascular functioning. Primordial prevention efforts aimed at preventing the development of cardiovascular risk should consider building on childhood psychosocial resources.
Direction finding with fewer receivers via time-varying preprocessing

We present a new technique for localizing multiple narrowband sources by a passive sensor array based on dimensionality-reducing time-varying preprocessing of the sensor outputs. The technique allows a significant reduction in the number of receivers required for the implementation with only two receivers sufficing in the extreme case. The estimation method we use is based on approximating the corresponding maximum likelihood estimator by a computationally simpler generalized least squares (GLS) estimator that is proved to be both consistent and asymptotically efficient. Simulation results confirming the theoretical results are included.
Optimization of n- and p-type TFETs Integrated on the Same  ${\rm InAs}/{\rm Al}_{x}{\rm Ga}_{1-x}{\rm Sb}$ Technology Platform

Design of a suitable technology platform is carried out in this paper for co-integration of simultaneously optimized n- and p-type tunnel field-effect transistors (TFETs). InAs/AlxGa1-xSb heterostructures are considered, and a 3-D full-quantum simulation approach is adopted to investigate the combined effect of Al mole fraction x and transverse quantization on band lineups at the heterojunction. Design optimization leads to a TFET pair with similar dimensions and feasible aspect ratios realized on the same InAs/Al0.05Ga0. 95Sb platform. These devices exhibit average subthreshold slopes below 60 mV/dec and relatively high ON-currents of 270 (n-TFET) and 120 μA/μm (p-TFET) at a low-supply voltage VDD=0.4 V. Combined ON- and OFF-state performance of the proposed technology platform is expected to be compatible with low operating power applications, while potential candidates for low standby power scenarios are obtained by reducing TFET cross sections from 10 to 7 nm.
Awakening Properties of Isoflurane, Sevoflurane, and Desflurane in Pediatric Patients After Craniotomy for Supratentorial Tumours

Background: The aim of this prospective, comparative, randomized study was to compare the inhalational anesthetics isoflurane, sevoflurane, and desflurane in pediatric patients undergoing craniotomy for excision of supratentorial tumors. We assessed early postoperative recovery outcome, intraoperative hemodynamics, and degree of brain swelling, as well as postoperative vomiting and shivering. Methods: Sixty patients scheduled for supratentorial brain tumor excision, were randomly allocated into 1 of 3 groups (20 patients each); isoflurane, sevoflurane, and desflurane group. After IV induction of anesthesia, maintenance was achieved using the inhalational anesthetic according to the allocated group. Tracheal extubation time was the primary endpoint. The secondary endpoints included: emergence time and the interval time needed to reach Aldrete score ≥9, intraoperative degree of brain swelling, intraoperative heart rate and mean arterial blood pressure, as well as postoperative vomiting and shivering. Results: The mean emergence time, extubation time, and the interval required to reach Aldrete score 9 were significantly shorter in the desflurane and sevoflurane groups than the isoflurane group. No statistically significant changes in the 3 groups regarding intraoperative brain swelling, hemodynamics, and postoperative shivering or vomiting were noted. Conclusions: Desflurane and sevoflurane can be used to facilitate early emergence from anesthesia in neurosurgical pediatric patients. Emergence times are shorter with desflurane or sevoflurane than with isoflurane. The patients who received desflurane or sevoflurane have similar intraoperative and postoperative incidence of adverse effects compared with those who received isoflurane. Thus, desflurane and sevoflurane can be considered as suitable for emergence in pediatric neurosurgical anesthesia.
Glycosylation Pattern of Mature Dimeric Leukocyte and Recombinant Monomeric Myeloperoxidase

The involvement of myeloperoxidase (MPO) in various inflammatory conditions has been the scope of many recent studies. Besides its well studied catalytic activity, the role of its overall structure and glycosylation pattern in biological function is barely known. Here, the N-glycan composition of native dimeric human MPO purified from neutrophils and of monomeric MPO recombinantly expressed in Chinese hamster ovary cells has been investigated. Analyses showed the presence of five N-glycans at positions 323, 355, 391, 483, 729 in both proteins. Site by site analysis demonstrated a well conserved micro- and macro-heterogeneity and more complex-type N-glycans for the recombinant form. Comparison of biological functionality of glycosylated and deglycosylated recombinant MPO suggests that glycosylation is required for optimal enzymatic activity. Data are discussed with regard to biosynthesis and the three-dimensional structure of MPO.
Weakly one-based geometric theories

Abstract We study the class of weakly locally modular geometric theories introduced in [4], a common generalization of the classes of linear SU-rank 1 and linear o-minimal theories. We find new conditions equivalent to weak local modularity: “weak one-basedness”, absence of type definable “almost quasidesigns”, and “generic linearity”. Among other things, we show that weak one-basedness is closed under reducts. We also show that the lovely pair expansion of a non-trivial weakly one-based ω-categorical geometric theory interprets an infinite vector space over a finite field.
TOTAL RESPIRATORY INERTANCE AND ITS GAS AND TISSUE COMPONENTS IN NORMAL AND OBESE MEN.

Total respiratory inertance may be defined as that component of the total impedance to breathing that relates to acceleration of respiratory gas and of all tissue elements (lungs, rib cage, diaphragm, and abdominal contents) that move during respiration. It is expressed in units of pressure required to overcome this inertial component of the total impedance and produce air flow acceleration of 1 L per second per second. Thus its units are centimeters H2O per liter per second2. Intuitively, one would suspect that the inertance of the chest and the abdomen should be increased in severely obese subjects. In investigations of total respiratory mechanics in excessively obese persons, we made measurements of total respiratory inertance. In addition, we attempted to separate the total respiratory inertance into its gas and tissue (including lung tissue, chest wall, and abdominal) components in three normal and three excessively obese subjects. These data form the substance of this report. Inertance data on the normal human respiratory system were first published by DuBois, Brody, Lewis, and Burgess (1) in 1956. These authors, assuming that the respiratory system behaves mechanically as a simple or "lumped" physical system, determined the total compliance and the natural frequency of the respiratory system. They then calculated the total inertance of the respiratory system by using the simple physical relationship by which the natural frequency of a system may be predicted if its elastic and inertial characteristics are known: fn = 1/274 1/jI *C, where fn
On the Computational Complexity and Effectiveness of N-Hub Shortest-Path Routing

In this paper, we study the computational complexity and effectiveness of a concept we term ldquoN-hub shortest-path routingrdquo in IP networks. N-hub shortest-path routing allows the ingress node of a routing domain to determine up to N intermediate nodes (ldquohubsrdquo) through which a packet will pass before reaching its final destination. This facilitates better utilization of the network resources, while allowing the network routers to continue to employ the simple and well-known shortest-path routing paradigm. Although this concept has been proposed in the past, this paper is the first to investigate it in depth. We apply N-hub shortest-path routing to the problem of minimizing the maximum load in the network. We show that the resulting routing problem is NP-complete and hard to approximate. However, we propose efficient algorithms for solving it both in the online and the offline contexts. Our results show that N-hub shortest-path routing can increase network utilization significantly even for N = 1. Hence, this routing paradigm should be considered as a powerful mechanism for future datagram routing in the Internet.
A survey on energy trading in smart grid

As the distributed energy generation and storage technologies are becoming economically viable, energy trading is gradually becoming a profit making option for end-users. This trend is further supported by the regulators and the policy makers as it aids the efficiency of power grid operations, reduces power generation cost and the Green House Gas (GHG) emissions. To that end, in this paper we provide an overview of distributed energy trading concepts in smart grid. First, we identify the motivation and the desired outcomes of energy trading framework. Then we present the enabling technologies that are required to generate, store, and communicate with the trading agencies. Finally, we survey on the existing literature and present an array of mathematical frameworks employed.