Miracle-dz/UniFAR-FTUs huggingface dataset:
Computer Use and the Wage Structure in Austria

In this paper we examine the relationship between computer premium and job position in Austria. We estimate cross-section wage equations and control for selectivity of computer use via a treatment effects model. We find that the size of the wage effect attributed to computer use varies significantly between job hierarchies. Persons in higher positions receive relatively lower rewards for computer use than workers at lower hierarchy levels. Overall we find that computerisation increased wage inequality in Austria. However, hierarchy-related differences in the relative computer premium in Austria might moderate the effects of computer use on the wage distribution.
Hormonal regulation of cytochrome P450 enzymes, cholesterol side-chain cleavage and 17 alpha-hydroxylase/C17-20 lyase in Leydig cells.

Testosterone biosynthesis in Leydig cells is dependent on two cytochrome P450 enzymes, cholesterol side-chain cleavage (P450scc) and 17 alpha-hydroxylase/C17-20 lyase (P450(17 alpha]. The expression of these two enzymes is differentially regulated by LH acting via its second messenger, cyclic adenosine 3',5'-monophosphate (cAMP), and by specific steroid hormones. P450scc is constitutively expressed in normal mouse Leydig cells and in MA-10 tumor Leydig cells. Chronic cAMP stimulation increases the steady state levels of P450scc mRNA and de novo P450scc protein synthesis. In contrast, cAMP is obligatory for de novo synthesis of P450(17 alpha) in normal mouse Leydig cells; P450(17 alpha) synthesis ceases in the absence of luteinizing hormone or cAMP. MA-10 tumor Leydig cells do not express P450(17 alpha) even after treatment with cAMP. The amount of P450(17 alpha) in Leydig cells is negatively regulated by testosterone acting by two distinct mechanisms. At low concentrations, testosterone acts via the androgen receptor to repress cAMP-induced synthesis of P450(17 alpha), whereas at high concentrations this steroid increases the rate of degradation of the enzyme by an oxygen-mediated mechanism. Both constitutive and cAMP-induced synthesis of P450scc protein and steady state levels of mRNA are modulated by glucocorticoids. In normal mouse Leydig cells, glucocorticoids repress P450scc synthesis and steady state levels of P450scc mRNA, whereas glucocorticoids stimulate P450scc synthesis and levels of P450scc mRNA in the tumor Leydig cells. (ABSTRACT TRUNCATED AT 250 WORDS)
Innovation through people

Creativity underpins innovation; innovation underpins enterprise. In the business world it is enterprises, not ideas or products on their own, that make money. Much attention is given to new product development and to processes of innovation. Indeed, there are increasingly popular techniques to support these processes. However, successful enterprises and effective corporate entrepreneurship need both ideas and people. While considerable attention is given to the product development side of innovation, it is a matter of debate whether the same degree of attention is always given to the people side, and the identification and development of people with entrepreneurial potential. When we consider entrepreneurs we have to look at how they think as well as at how they act – and thinking contains both conscious and unconscious elements. Techniques generally address conscious rather than unconscious thought processes. There are some aspects of our creative thinking processes that we can't readily explain. We need to get “inside the mind” of the innovator.
Improved employment and education outcomes in households of HIV-infected adults with high CD4 cell counts: evidence from a community health campaign in Uganda

Background:There is limited evidence on the association between socioeconomic outcomes and CD4 counts in populations that include HIV-infected adults who have high CD4 counts or have not been diagnosed. We examined this association among adults in a rural Ugandan parish. Methods:A community health campaign offering diagnostic and treatment services for HIV and other diseases was conducted with Ministry of Health support. Data on campaign participants’ education and employment were collected and a detailed household socioeconomic survey was conducted among a subset of participants. Regression analyses were used to assess relationships between CD4 count and employment and education outcomes. Results:A total of 2323 adults (74% of the community) participated in the campaign; 179 of 2282 (7.8%) tested HIV-positive and 46% were newly diagnosed. Among HIV-infected adults not on antiretroviral therapy (ART), those with CD4 at least 500 worked 6.9 more days/month (P < 0.01; 39% more) and 2.5 more h per day (P < 0.05, 44% more) than those with CD4 less than 200. These effects were not significantly different from the effects for those with CD4 350–499. Children aged 6–11 years in households of adults with CD4 at least 350 did not have significantly different school enrollment rates than children in households of adults with CD4 less than 350, but differences were larger among children aged 12–18 years. Conclusion:Outcomes of HIV-infected adults with CD4 at least 350 were better than those of adults with CD4 less than 200 and resembled those of HIV-uninfected adults. The results suggest that early ART initiation may generate economic benefits by preventing a decline in socioeconomic status, but further research is needed to determine the CD4 threshold at which these benefits would be largest.
An analysis of Hungarian agri-food export competitiveness.

The main purpose of this study is to provide an overview of the export growth trends in the Hungarian agri-food sector over the last decade and to identify the obstacles hindering the sector’s development. We used constant market share analysis to break down into components the changes in export growth. Almost without exception, the increasing market size accounted for most of the export growth to 14 countries. The commodity (market composition) and competitiveness effects produced varied results and were not so positive. This shows that the Hungarian export structure was less adaptive to changes in demand in the target export markets. There were positive examples however, such as Italy and Slovakia, where the competitiveness effect explained 82 and 64 per cent respectively of the Hungarian export growth. In Romania almost one third of the total Hungarian agri-food export growth was explained by the improved competitiveness. The negative examples are numerous; the most important is the trade relations with Poland where the competitiveness effect almost halved the measured export growth potential. By analysing the price and quality competitiveness of the cereal and oilseed commodities with unit value calculations we could show that the market position of these relatively lower-priced products could be improved.
Audit risk and audit programmes: archival evidence from four Dutch audit firms

The audit risk model has become an extremely important element in audit practice. The basic intuition behind the model is that changes in risk should affect the work of the auditor. However, little systematic empirical evidence has been published on the assessment of audit risk and its effect on audit work. This study, using documentation from actual audits and follow-up interviews, provides such evidence. Assessments of audit risk and audit programme details have been obtained from eight clients of four Dutch audit firms. Audit risk assessments are obtained for two risk categories: (1) audit risk factors, such as the degree of client management turnover or the quality of the client's internal audit department; and (2) audit risk model variables (inherent or control risk), related to the account or assertion being audited. The results indicate that there is substantial variation in audit risk factors between clients and among the audit risk factors per client. To a lesser extent these findings hold for the risk model variables. The study also indicates that to some degree there is risk variation over time. Variability of risk factor assess-ments over time is higher than variability of risk model variable assessments over time. Audit programmes differ substantially between clients and, to a lesser extent, over time. Interestingly, the only two engagements with a change in the audit programme were the clients with most risk factor changes. The study also identifies factors other than risk, such as a change in the audit team, that influence audit programme planning. The observation in Dutch audit practice of variation in both risk assessments and audit programmes highlights the opportunity to design risk-adjusted audits, which are both efficient and effective. In addition, this observation encourages the carrying out of further research to fine-tune our models concerning which factors are most important within the audit risk model and to the audit planning process.
Understanding service quality in the new public sector

Highlights the increasing emphasis on customers and service quality in the new public sector. Emphasises the bias towards hard, easily quantifiable data and a focus on external customers in the measurement of service quality. Explores relationships through which grants for social housing are bid for and allocated and the programme managed. Reviews measures of quality in relation to understanding such service relationships. Offers the Service Template Process within a process consultancy framework as an alternative. Findings emphasise the importance of partnership between the Housing Corporation, Local Authorities and Registered Social Landlords (Housing Associations) in ensuring quality in the funding of social housing and the need for longer time scales for joint planning activity. The suitability of the process to help highlight issues critical to a service relationship is also discussed.
Pay Differences among the Highly Paid: The Male-Female Earnings Gap in Lawyers' Salaries

This article uses very detailed information on graduates of the University of Michigan Law School to examine male-female pay differences in that population. Men and women in this population have virtually identical human capital on graduation from law school, allowing us to examine carefully the different impact of children and work history on men's and women's careers and earnings. Taking time from work in order to care for children reduces wages significantly, but a rich set of controls, including childcare, work history, school performance, and job setting measures, still leave one-fourth to one-third of the earnings gap unexplained.
THE LIMITS OF KNOWLEDGE MANAGEMENT FOR UK PUBLIC SERVICES MODERNIZATION: THE CASE OF PATIENT SAFETY AND SERVICE QUALITY

This article assesses the contribution of management of knowledge across organizational and professional boundaries towards improved public services. We empirically investigate the potential for knowledge sharing within the context of the NHS modernization agenda, taking as our focus the current ‘patient safety’ policy agenda. Specifically, we evaluate the introduction of a knowledge management system, namely the National Reporting and Learning System (NRSL) and its impact in the area of operating theatres within a university teaching hospital. We suggest that government policy in this area needs to reflect more upon limits to the management of knowledge and issues of the nature of knowledge, professional cultures and institutional power and politics.
The energy transition in rural China

Based on an analysis of a nationally representative rural household survey and various sources of aggregate statistics, we explore patterns of residential energy use in rural China within the conceptual framework of the energy transition. We find that residential energy consumption varies tremendously across geographic regions due to disparities of access to different energy sources, prices, climate, income and urbanisation level. Household demographic characteristics, in particular household size, have an important impact on residential energy use. Aggregate time series data show that the transition from biomass to modern commercial sources is still at an early stage, and cross-sectional data suggest that incomes may have to rise substantially in order for absolute biomass use to fall. We also find that energy use patterns as a function of net income, rather than total expenditure, are more consistent with the energy transition model in rural China.
Ultrastructural Localization of Caspase-14 in Human Epidermis

Caspase-14 has been implicated in the formation of stratum corneum because of its specific expression and activation in terminally differentiating keratinocytes. However, its precise physiological role and its protein substrate are elusive. We studied the ultrastructural localization of caspase-14 in human epidermis to compare its distribution pattern with that of well-characterized differentiation markers. Immunogold cytochemistry confirmed that caspase-14 is nearly absent in basal and spinous layers. In the granular, layer nuclei and keratohyalin granules were labeled with increasing intensity towards the transitional layer. Particularly strong caspase-14 labeling was associated with areas known to be occupied by involucrin and loricrin, whereas F-granules, occupied by profilaggrin/filaggrin, were much less labeled. A high density of gold particles was also present at the forming cornified cell envelope, including desmosomes. In corneocytes, intense labeling was both cytoplasmic and associated with nuclear remnants and corneodesmosomes. These observations will allow focusing efforts of biochemical substrate screening on a subset of proteins localizing to distinct compartments of terminally differentiated keratinocytes.
Prediction, explanation and big(ger) data: a middle way to measuring and modelling the perceived success of a volunteer tourism sustainability campaign based on ‘nudging’

The overall aim of this paper was to explore the dichotomy between explanation and prediction and to suggest that there is a middle way. Explanation has often been the domain of academics while prediction has often been the domain of businesses. The former have frequently used smaller sample sizes, the latter larger sample sizes and now increasingly data that have high volume, high velocity, and high variety, i.e. big data. These differences may place the parties at opposite ends of a spectrum which suggests that there is a middle way. This middle way uses ‘automatic linear modelling’ that can cope with big data and presents the results as visualisations. An example is outlined based on a sustainability campaign involving leaders in the context of volunteer tourism. The campaign used an informational ‘nudge’ approach. The results of the study are discussed in relation to both the application of the technique and the success of the campaign. It is pointed out that the technique is exploratory but can aid both prediction and theory building in the area of volunteer tourism and that academics must not be afraid to embrace new methods that may be less conventional but bring the universities and industry closer together.
The impact of recreational MDMA ‘ecstasy’ use on global form processing

The ability to integrate local orientation information into a global form percept was investigated in long-term ecstasy users. Evidence suggests that ecstasy disrupts the serotonin system, with the visual areas of the brain being particularly susceptible. Previous research has found altered orientation processing in the primary visual area (V1) of users, thought to be due to disrupted serotonin-mediated lateral inhibition. The current study aimed to investigate whether orientation deficits extend to higher visual areas involved in global form processing. Forty-five participants completed a psychophysical (Glass pattern) study allowing an investigation into the mechanisms underlying global form processing and sensitivity to changes in the offset of the stimuli (jitter). A subgroup of polydrug-ecstasy users (n=6) with high ecstasy use had significantly higher thresholds for the detection of Glass patterns than controls (n=21, p=0.039) after Bonferroni correction. There was also a significant interaction between jitter level and drug-group, with polydrug-ecstasy users showing reduced sensitivity to alterations in jitter level (p=0.003). These results extend previous research, suggesting disrupted global form processing and reduced sensitivity to orientation jitter with ecstasy use. Further research is needed to investigate this finding in a larger sample of heavy ecstasy users and to differentiate the effects of other drugs.
Comparing Audio and Video Data for Rating Communication

Video recording has become increasingly popular in nursing research, adding rich nonverbal, contextual, and behavioral information. However, benefits of video over audio data have not been well established. We compared communication ratings of audio versus video data using the Emotional Tone Rating Scale. Twenty raters watched video clips of nursing care and rated staff communication on 12 descriptors that reflect dimensions of person-centered and controlling communication. Another group rated audio-only versions of the same clips. Interrater consistency was high within each group with Interclass Correlation Coefficient (ICC) (2,1) for audio . 91, and video = . 94. Interrater consistency for both groups combined was also high with ICC (2,1) for audio and video = . 95. Communication ratings using audio and video data were highly correlated. The value of video being superior to audio-recorded data should be evaluated in designing studies evaluating nursing care.
An Analysis of Corporate Donations: United Kingdom Evidence

Drawing a framework from stakeholder theory, this study uses 1994 data drawn from 100 United Kingdom listed companies to test empirically whether the level of discretionary donations made by companies to charitable, social and political causes is related to four company‐specific factors, namely leverage, company size, profitability and ownership structure. Consistent with our hypotheses, the results indicate that the decision to contribute funds to charities and other bodies is positively related to company size and profitability and negatively related to leverage. However, the study provides no support for the view that there is a link between discretionary donations and a company's ownership structure.
Overview of the role of B2-adrenergic receptor variants in human hypertension

Essential hypertension isa complex traitto whichmultifactorial origin arising from an interaction between genetic and environmental factorscontribute interactively. Consequently, the identification of genes related to hypertension is complicated by the heterogeneity of its causes and the possibility that various genes with moderate impacts, probably acting in a same manner, affect blood pressure and the occurrence of hypertension. Multiple studies have suggested that variation within the β2-adrenergic receptor (ADRB2) is implicated in blood pressure regulation and the development of hypertension. The evidence for ADRB2 gene association with hypertension is not conclusive. There are conflicting reports on the association of these polymorphisms with hypertension. Several reports have suggested the association of the ADRB2 variants with the prevalence of hypertension and systolic blood pressure (BP)whilst others refuted the association. The role of these findings is reviewed here, and their potential clinical influences in human hypertension.
Can Wrongful Discharge Law Enhance Employment?

The extent of government in private contractual relationships is a vexing public policy issue. This article explores, both theoretically and empirically, the degree to which such intervention may enhance employment. Economists traditionally have held that interventions such as wrongful discharge protections simply undo the original intent of the parties to an employment contract. We find that both good faith as well as implied contract exceptions to employment-at-will may enhance employment, particularly in occupations characterised by high levels of investment and skill. This suggests that under the appropriate conditions, labour law may enhance the operation of a competitive market. Copyright 2007 The Author(s). Journal compilation Royal Economic Society 2007.
A Model-driven Privacy Compliance Decision Support for Medical Data Sharing in Europe

Summary Objectives: Clinical practitioners and medical researchers often have to share health data with other colleagues across Europe. Privacy compliance in this context is very important but challenging. Automated privacy guidelines are a practical way of increasing users’ awareness of privacy obligations and help eliminating unintentional breaches of privacy. In this paper we present an ontology-plus-rules based approach to privacy decision support for the sharing of patient data across European platforms. Methods: We use ontologies to model the required domain and context information about data sharing and privacy requirements. In addition, we use a set of Semantic Web Rule Language rules to reason about legal privacy requirements that are applicable to a specific context of data disclosure. We make the complete set invocable through the use of a semantic web application acting as an interactive privacy guideline system can then invoke the full model in order to provide decision support. Results: When asked, the system will generate privacy reports applicable to a specific case of data disclosure described by the user. Also reports showing guidelines per Member State may be obtained. Conclusion: The advantage of this approach lies in the expressiveness and extensibility of the modelling and inference languages adopted and the ability they confer to reason with complex requirements interpreted from high level regulations. However, the system cannot at this stage fully simulate the role of an ethics committee or review board.
Performance Decline and Turnaround in Public Organizations: A Theoretical and Empirical Analysis

Public sector performance is currently a significant issue for management practice and policy, and especially the turnaround of those organizations delivering less than acceptable results. Theories of organizational failure and turnaround derive largely from the business sector and require adaptation to the public service. The performance of public organizations is more complex to measure, is related to institutional norms, and the idea of ‘failure’ is problematic. Empirical findings from a real-time, longitudinal study of poorly performing English local authorities are used to develop an initial theory of performance failure and turnaround suited to public organizations. The paper argues that the typical performance of public organizations over time is cyclical. Where cognition and leadership capability are absent, organizations fail to self-initiate turnaround. In this situation authoritative external intervention is necessary. The strategies applied are principally concerned with building a leadership capability that engages senior politicians and managers in order to overcome inertia and collective action problems. The theory is presented in the form of seven propositions that provide a basis for further research across the public sector.