Miracle-dz/UniFAR-FTUs huggingface dataset:
“I've started to move into my own body”: Music therapy with women suffering from eating disorders

This article addresses individual music therapy with two young women suffering from eating disorders, i.e. anorexia and bulimia nervosa. The theoretical approach is psychodynamic inspired, focusing a relating experience through music to promote health. The clinical cases stem from a music therapy practice at a specialized unit for eating disorders. The first example describes Susan's music therapy process towards a renewed self-confidence, elucidated through creative writing, musical exploration and body movements. In the second case, Helen finds it hard to connect body and mind, i.e. relate inner feelings to words. Through music therapy, she explores her inner self by searching for “little Helen”, which eventually leads to a closer connection between inner and outer reality. In the discussion, we suggest relating experience through music to empower the clients' strength, support inner healing resources and contribute to a living bridge between body and mind, which subsequently support healing resources and nourish hope of a normal life, i.e. support life itself.
Bone Morphogenetic Proteins Stimulate Angiogenesis through Osteoblast-Derived Vascular Endothelial Growth Factor A.

During bone formation and fracture healing there is a cross-talk between endothelial cells and osteoblasts. We previously showed that vascular endothelial growth factor A (VEGF-A) might be an important factor in this cross-talk, as osteoblast-like cells produce this angiogenic factor in a differentiation-dependent manner. Moreover, exogenously added VEGF-A enhances osteoblast differentiation. In the present study we investigated, given the coupling between angiogenesis and bone formation, whether bone morphogenetic proteins (BMPs) stimulate osteoblastogenesis and angiogenesis through the production of VEGF-A. For this we used the murine preosteoblast-like cell line KS483, which forms mineralized nodules in vitro, and an angiogenesis assay comprising 17-d-old fetal mouse bone explants that have the ability to form tube-like structures in vitro. Treatment of KS483 cells with BMP-2, -4, and -6 enhanced nodule formation, osteocalcin mRNA expression, and subsequent mineralization after 18 d of culture. This wa.
Modeling Semantic Relatedness using Global Relation Vectors

Word embedding models such as GloVe rely on co-occurrence statistics from a large corpus to learn vector representations of word meaning. These vectors have proven to capture surprisingly fine-grained semantic and syntactic information. While we may similarly expect that co-occurrence statistics can be used to capture rich information about the relationships between different words, existing approaches for modeling such relationships have mostly relied on manipulating pre-trained word vectors. In this paper, we introduce a novel method which directly learns relation vectors from co-occurrence statistics. To this end, we first introduce a variant of GloVe, in which there is an explicit connection between word vectors and PMI weighted co-occurrence vectors. We then show how relation vectors can be naturally embedded into the resulting vector space.
Educational research within postcolonial Africa: a critique of HIV/AIDS research in Botswana

This paper uses the postcolonial lens to highlight that mainstream research in postcolonial societies still ignores, marginalizes and suppresses other knowledge systems and ways of knowing. The marginalization of local knowledge systems, it is argued, was established in the colonial times that relegated all things indigenous or from the colonized communities as unworthy, uncivilized, barbaric and superstitious. Systematic efforts to inscribe Western ways of cultural, economic, political and social systems were applied during the colonial times and maintained in the post‐independence era. The educational system did not escape the colonial construction of the colonized subjects and their relegation to otherness. Years after the struggle for independence the content of what is taught, methods of teaching and research remain Western in non‐Western contexts. This does not only alienate the ‘othered’ from their own knowledge systems, it can be a matter of life and death as demonstrated by the HIV/AIDS information and education campaign. Using excerpts from studies on HIV/AIDS, the paper highlights that interventions to prevent the spread of HIV/AIDS, legitimized by conventional/Western research knowledge and frameworks, have alienated the people from the struggle to prevent the spread of the virus. Findings from a number of research studies on HIV/AIDS in Botswana are analyzed within the framework of current prevention strategies, more specifically posters and cartoons used in the campaign against HIV/AIDS, to illustrate the marginalization of other knowledge systems and the intersection of the ‘otherness’ ideology with mainstream First World research methodologies.
Reconstruction of rat retinal progenitor cell lineages in vitro reveals a surprising degree of stochasticity in cell fate decisions

In vivo cell lineage-tracing studies in the vertebrate retina have revealed that the sizes and cellular compositions of retinal clones are highly variable. It has been challenging to ascertain whether this variability reflects distinct but reproducible lineages among many different retinal progenitor cells (RPCs) or is the product of stochastic fate decisions operating within a population of more equivalent RPCs. To begin to distinguish these possibilities, we developed a method for long-term videomicroscopy to follow the lineages of rat perinatal RPCs cultured at clonal density. In such cultures, cell-cell interactions between two different clones are eliminated and the extracellular environment is kept constant, allowing us to study the cell-intrinsic potential of a given RPC. Quantitative analysis of the reconstructed lineages showed that the mode of division of RPCs is strikingly consistent with a simple stochastic pattern of behavior in which the decision to multiply or differentiate is set by fixed probabilities. The variability seen in the composition and order of cell type genesis within clones is well described by assuming that each of the four different retinal cell types generated at this stage is chosen stochastically by differentiating neurons, with relative probabilities of each type set by their abundance in the mature retina. Although a few of the many possible combinations of cell types within clones occur at frequencies that are incompatible with a fully stochastic model, our results support the notion that stochasticity has a major role during retinal development and therefore possibly in other parts of the central nervous system.
Academic Achievement and Social Adjustment of Children Young for Their Grade Placement

The general practice among public schools of setting an arbitrary chronological age limit for admission to kindergarten and Grade I is probably necessary from a practical point of view, but it has created problems for teachers in providing for the varied needs of individuals in the kindergarten and in the later grades. The child whose birthday comes in the month following the cut-off point enters kindergarten when he is chronologically five yearsand eleven months old, while the youngest child in the group is a year or more younger. The range of mental ages is even wider. Some schools, in an attempt to meet the needs created by individual differences in development, allow children younger than the limits set to enter school on the basis of readiness, as shown on individual intelligence tests. Other schools, through the provision of an ungraded primary school, permit shifting from one group to another on the basis of performance. In the latter schools, most children would take the conventional four years to prepare for Grade IV, others might take five years, and still others might complete this period of training in three. Another plan for meeting the needs of the superior individuals in the group is to allow double promotion or skipping of grades at any level where it seems desirable. Some schools admit chil-
Dirichlet regularity and degenerate diffusion

Let Ω C ℝ N be an open and bounded set and let m: Ω→ (0, oo) be measurable and locally bounded. We study a natural realization of the operator mΔ in Co(Ω) := {u ∈ C(Ω): u |∂Ω = 0}. If Ω is Dirichlet regular, then the operator generates a positive contraction semigroup on C 0 (Ω) whenever 1/m ∈ L p loc (Ω) for some p > N/2. If m(x) does not go fast enough to 0 as x → ∂Ω, then Dirichlet regularity is necessary. However, if |m(x)| ≤ c · dist(x, ∂Ω) 2 , then we show that mΔ 0 generates a semigroup on C 0 (Ω) without any regularity assumptions on Ω. We show that the condition for degeneration of m near the boundary is optimal.
[Relationship among caries, gingivitis and fluorosis and socioeconomic status of school children].

OBJECTIVE To determine the relationship between the socioeconomic status and dental caries, gingivitis and fluorosis among Brazilian school children. METHODS One thousand students aged 12 from private and public schools were examined. The indexes used were DMFT or S (Decayed, Missing and Filled Teeth or Surfaces Index), BI (Bleeding Index), and TFI (Thylstrup and Feyerskov Index). The socioeconomic level was determined according family income and parents' educational level. RESULTS Parents' educational level data revealed a strong Pearson's correlation with income. No correlation was observed between dental caries prevalence, gingivitis and fluorosis and the studied social economic variables. The DMFT in private schools was 1.54+/-2.02, and in public schools was 2.48+/-2.51. BI was 14.7%+/-12.7% in private schools and 21.7%+/- 17.9% in public ones. The prevalence of fluorosis was 60.8% and 49.9%, respectively). These differences were statistically significant (p<0.05). Individuals with a larger number of decayed surfaces and the ones with a larger percent of bleeding surfaces were seen in public schools. CONCLUSIONS The socioeconomic level variables, income and parents' educational level, did not correlate with the events analyzed in the study. Other socioeconomic variables probably contributed to the observed differences between students from private and public schools.
Residential movement among the poor: the constraints on housing choice in Latin American cities.

"The paper examines the validity of current theories of intra-city migration, subjecting those theories to the test of explaining new data collected in a total of 13 low-income settlements in three Latin American cities: Bogota, Mexico City, and Valencia, Venezuela. The study focuses attention upon the principal reception points for migrants; the location of previous place of residence for contemporary barrio dwellers; [and] the tenure and dwelling characteristics of previous places of residence. The authors conclude that residential patterns in Latin American cities are less the outcome of migrant choice, as some theories argue, and more the product of constraints imposed upon the land and housing markets. "
Learning Styles Inequity for Small to Micro Firms (SMFs): Social Exclusion through Work-Based E-Learning Practice in Europe

Purpose – The elearn2work study of learning styles in the context of small to micro firms' (SMFs) and their perceived satisfaction has identified some important finding specific to e‐learning content design, delivery and international standards development.Design/methodology/approach – The method of research adopts a deductive rather than an inductive approach via descriptive profiling and multivariate statistical analysis.Findings – From the elearn2work study we have identified tentative findings that indicate e‐learning inequity for many SMF learners including employees and managers. From our research there is a clear gap between the profile of SMF learners, in the context of their learning style, and the typical content that is currently being designed for e‐learning provision. The sector is driven by analytic type educators/trainers who are frequently not a reflection of SMF learners.Originality/value – It could be argued that many SMF workers are currently being socially excluded from e‐learning prov.
Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence.

The present association study tested whether genetic variation of the GABAB receptor (GABABR1) gene confers vulnerability to alcohol dependence. The genotypes of three DNA sequence variants in exons 1a1, 7 and 11 of the GABABR1 gene were assessed in 234 German controls and 350 German alcohol-dependent subjects, including three more homogeneous subgroups of alcoholics, marked by (1) history of parental alcoholism (n = 121); (2) history of alcohol withdrawal seizure or delirium (n = 108); and (3) comorbidity of dissocial personality disorder (n = 60). The allele frequencies of none of the investigated GABABR1 variants differed significantly between the controls and the groups of alcoholics when a correction for multiple testing was taken into account (P > 0.004). However, trends (P < 0.10) towards an excess of the Ser489 allele of the exon 7 polymorphism were found in the subgroups of alcoholics, and of the common allele of the exon 11 polymorphism in the entire sample of alcoholics (P = 0.032), alcoholics with parental alcoholism (P = 0.084) and the dissocial alcoholics (P = 0.037). Our findings suggest that the investigated GABABR1 variants do not contribute a substantial effect (RR > 3) to the genetic variance of alcohol dependence. Nevertheless, the hints towards potential allelic associations of the exon 7 and 11 polymorphisms with dissocial alcoholism emphasize further studies to test more defined phenotype-genotype relationships.
A comparative study of web pages classification methods applied to health consumer web pages

These days, the Internet is developing at an exponential rate and can cover just about any data required. Nonetheless, the immense measure of web pages makes it more difficult to effectively discover the target data by a user. Therefore, an efficient method, for classifying this huge amount of data is essential if the web pages are to be exploited to its full potential. In the domain of automatic web page classifier many approaches have been tried to solve this problem using different Machine learning-based algorithms including Support Vector Machine (SVM), Naïve Bayes, Decision Tree, K-Nearest Neighbor (K-NN) and Neural Networks. However, there is a lack of comparison between these algorithms to find a better framework for the classification and analysis of health related web pages. In this research study, we compare two commonly used supervised Machine Learning algorithms; Support Vector Machines (SVM) and Naïve Bayes to classify web pages which provide drugs related information of patients for example side effects, patient action and follow-up information for patients. We use Unified Medical Language System (UMLS) to annotate the health related concepts in Web pages and train SVM and Naïve Bayes classifiers in General Architecture for Text Engineering to classify health related and non-health related Web pages. The evaluation was performed using K-fold cross validation using four runs on a data set of fifty Web pages. Results found that SVM performed better to classify health and non-health related pages in terms of precision, recall and F-measure.
Production of Aerated Foamed Concrete with Industrial Waste from the Gems and Jewels Sector of Rio Grande do Sul-Brazil

The use of solid waste for the development of new building materials has been an alternative to reduce environmental impacts through the preservation of natural resources. In this context, this paper evaluates the possibility of using agate gemstone waste, called rolled powder, which basically consists of silica (SiO2), in the manufacture of aerated foamed concrete blocks completely replacing the natural sand. Preformed foam was used as the air entrained by mechanical stirring with a mixture of natural foaming agents derived from coconut. To produce test specimens, the water/cement ratio and foam concentrations were varied, with three and four levels, respectively. The specimens were left for 28 days at room temperature to be cured, and then underwent analysis to determine their compressive strength, density, and the distribution of air-voids. The experiments demonstrated that the best water/cement ratio was 1.28 for 18% (of total solid mass) addition of foam, which generated a sample with a density of 430 kg/m3, and a compressive strength of 1.07 MPa. The result for compressive strength is 11% smaller than the requirements of the Brazilian standard (NBR 13438) for autoclaved aerated concrete blocks, but the results are promising.
Fibroblast growth factor 2 is an essential cardioprotective factor in a closed‐chest model of cardiac ischemia‐reperfusion injury

Fibroblast growth factor 2 (FGF2) is cardioprotective in in vivo models of myocardial infarction; however, whether FGF2 has a protective role in in vivo ischemia‐reperfusion (IR) injury, a model that more closely mimics acute myocardial infarction in humans, is not known. To assess the cardioprotective efficacy of endogenous FGF2, mice lacking a functional Fgf2 gene (Fgf2−/−) and wild‐type controls were subjected to closed‐chest regional cardiac IR injury (90 min ischemia, 7 days reperfusion). Fgf2−/− mice had significantly increased myocardial infarct size and significantly worsened cardiac function compared to wild‐type controls at both 1 and 7 days post‐IR injury. Pathophysiological analysis showed that at 1 day after IR injury Fgf2−/− mice have worsened cardiac strain patterns and increased myocardial cell death. Furthermore, at 7 days post‐IR injury, Fgf2−/− mice showed a significantly reduced cardiac hypertrophic response, decreased cardiac vessel density, and increased vessel diameter in the peri‐infarct area compared to wild‐type controls. These data reveal both acute cardioprotective and a longer term proangiogenic potential of endogenous FGF2 in a clinically relevant, in vivo, closed‐chest regional cardiac IR injury model that mimics acute myocardial infarction.
Multi-Party Privacy-Preserving Set Intersection with Quasi-Linear Complexity

Secure computation of the set intersection functionality allows n parties to find the intersection between their datasets without revealing anything else about them. An efficient protocol for such a task could have multiple potential applications in commerce, health care, and security. However, all currently known secure set intersection protocols for n > 2 parties have computational costs that are quadratic in the (maximum) number of entries in the dataset contributed by each party, making secure computation of the set intersection only practical for small datasets. In this paper, we describe the first multi-party protocol for securely computing the set intersection functionality with both the communication and the computation costs that are quasi-linear in the size of the datasets. For a fixed security parameter, our protocols require O(n2k) bits of communication and O(n2k) group multiplications per player in the malicious adversary setting, where k is the size of each dataset. Our protocol follows the basic idea of the protocol proposed by Kissner and Song, but we gain efficiency by using different representations of the polynomials associated with users’ datasets and careful employment of algorithms that interpolate or evaluate polynomials on multiple points more efficiently. Moreover, the proposed protocol is robust. This means that the protocol outputs the desired result even if some corrupted players leave during the execution of the protocol. key words: multi-party set intersection, privacy-preserving set operation
Regulation of N-Formyl Peptide-Mediated Degranulation by Receptor Phosphorylation1

One of the major functions of the N-formyl peptide receptor (FPR) is to mediate leukocyte degranulation. Phosphorylation of the C-terminal domain of the FPR is required for receptor internalization and desensitization. Although arrestins mediate phosphorylation-dependent desensitization, internalization, and initiation of novel signaling cascades for a number of G protein-coupled receptors, their roles in FPR regulation and signaling remain unclear. CXCR1-mediated degranulation of RBL-2H3 cells is promoted by arrestin binding. To determine whether receptor phosphorylation or arrestin binding is required to promote FPR-mediated degranulation, we used RBL-2H3 cells stably transfected with either the wild-type FPR or a mutant form, ΔST, which is incapable of undergoing ligand-stimulated phosphorylation. We observed that stimulation of wild-type FPR resulted in very low levels of degranulation compared with that mediated by cross-linking of the FcεRI receptor. Stimulation of the ΔST mutant, however, resulted in levels of degranulation comparable to those of the FcεRI receptor, demonstrating that neither receptor phosphorylation nor arrestin binding was necessary to initiate FPR-mediated degranulation. Degranulation initiated by the ΔST mutant was proportional to the level of active cell surface receptor, suggesting that either receptor internalization or desensitization may be responsible for terminating degranulation of the wild-type FPR. To distinguish between these possibilities, we used a partially phosphorylation-deficient mutant of the FPR that can undergo internalization, but not desensitization. Degranulation by this mutant FPR was indistinguishable from that of the ΔST mutant, indicating that FPR phosphorylation or binding of arrestin but not internalization terminates the degranulation response.
Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells

With the endothelium present, the maximum response of rat isolated aorta to clonidine was much lower than that to noradrenaline. Removal of endothelium enhanced the response to both adrenoceptor agonists and the clonidine‐induced maximum contraction became almost equal to that produced by noradrenaline, although it was much more sensitive to inhibition by flunarizine and nifedipine. These results indicate that clonidine and noradrenaline activate receptors present in the endothelial cells and that these receptors are highly sensitive to clonidine.