Miracle-dz/UniFAR-FTUs huggingface dataset:
Network Analysis of Bogotá's Ciclovía Recreativa, a Self-Organized Multisectorial Community Program to Promote Physical Activity in a Middle-Income Country

Purpose. Conduct a social network analysis of the health and non–health related organizations that participate in Bogotá's Ciclovía Recreativa (Ciclovía). Design. Cross-sectional study. Setting. Ciclovía is a multisectoral community-based mass program in which streets are temporarily closed to motorized transport, allowing exclusive access to individuals for leisure activities and physical activity. Subjects. Twenty-five organizations that participate in the Ciclovía. Measures. Seven variables were examined by using network analytic methods: relationship, link attributes (integration, contact, and importance), and node attributes (leadership, years in the program, and the sector of the organization). Analysis. The network analytic methods were based on a visual descriptive analysis and an exponential random graph model. Results. Analysis shows that the most central organizations in the network were outside of the Health sector and include Sports and Recreation, Government, and Security sectors. The organizations work in clusters formed by organizations of different sectors. Organization importance and structural predictors were positively related to integration, while the number of years working with Ciclovía was negatively associated with integration. Conclusion. Ciclovía is a network whose structure emerged as a self-organized complex system. Ciclovía of Bogotá is an example of a program with public health potential formed by organizations of multiple sectors with Sports and Recreation as the most central.
Toward a General Theory of Strategic Action Fields*

In recent years there has been an outpouring of work at the intersection of social movement studies and organizational theory. While we are generally in sympathy with this work, we think it implies a far more radical rethinking of structure and agency in modern society than has been realized to date. In this article, we offer a brief sketch of a general theory of strategic action fields (SAFs). We begin with a discussion of the main elements of the theory, describe the broader environment in which any SAF is embedded, consider the dynamics of stability and change in SAFs, and end with a respectful critique of other contemporary perspectives on social structure and agency.
Be in g Physical Psychological Spiritual Belonging Physical Social Community Becoming Leisure Growth Prac tical

Each year colleges, universities, corporations, and private organizations award scholarships recognizing students who demonstrate outstanding academic achievement, leadership ability, a commitment of service to others, exceptional talents, and involvement in extracurricular activities. Some scholarships provide important incentives for young people to pursue their careers and interests while others encourage student enrollment in particular majors or specific career fields.
Reduced-complexity image segmentation under parallel Markov Random Field formulation using graph partitioning

Markov Random Field (MRF) algorithms are powerful tools in image analysis to explore contextual information of data. However, the application of these methods to large data means that alternative approaches must be found to circumvent the NP-hard complexity of the MRF optimization. We introduce a MRF-based framework that overcomes this issue by using graph partitioning. The computational complexity is decreased as the optimization/parameter estimation is executed on small subgraphs. PMRF targets 3D microCT datasets, but we include evaluation on the Berkeley Segmentation Dataset (ranking 7th place) to fully compare our method with well-known segmentation algorithms. Segmentation results on the microCT datasets achieve precision higher than 95%.
Campylobacter enteritis.

Mulley, G, and Mitchell, J R A, Lancet, 1976, 1, 1397. 2 Mulley, G, and Mitchell, J R A, British Medical J7ournal, 1976, 2, 944. 3 Campbell, S, and Whitehead, M I, British Medical Journal, 1977, 1, 104. 4 Campbell, S, et al, in The Management of the Menopause and Post-Menopausal Years, ed S Campbell, p 149. Lancaster, Medical and Technical Publishing, 1976. Campbell, S, and Whitehead, M, in Clinics in Obstetrics and Gynaecology, Vol. 4, No 1, ed R Greenblatt and J Studd, p 31. Philadelphia and London, Saunders, 1977. Coope, J, in The Management of the Menopause and Post-Menopausal Years, ed S Campbell, p 159. Lancaster, Medical and Technical Publishing, 1976. Mulley, G, and Mitchell, J R A, British Medical Journal, 1977, 2, 766. 8 Coope, J, Thomson, J M, and Poller, L, British Medical _Journal, 1975, 4, 139.
Safety and efficacy of the percutaneous treatment of bile leaks in hepaticojejunostomy or split‐liver transplantation without dilatation of the biliary tree

Biliary leaks complicating hepaticojejunostomy (HJA) or fistulas from cut surface are severe complications after liver transplantation (LT) and split‐liver transplantation (SLT). The aim of the study was to describe our experience about the safety and efficacy of radiological percutaneous treatment without dilatation of intrahepatic biliary ducts. From 1990 to 2006, 1595 LTs in 1463 patients were performed in our center. In 1199 LTs (75.2%), a duct‐to‐duct anastomosis was performed, and in 396 (24.8%), an HJA was performed. One hundred twenty‐nine anastomotic or cut‐surface bile leakages occurred in 115 patients. Sixty‐two biliary leaks occurred in 54 patients with HJA; in 48 cases, an anastomotic fistula was found. Cut‐surface fistulas occurred in 14 cases: 5 in right SLTs and 5 in left SLTs. Twenty‐two patients were treated with 23 percutaneous approaches for 17 HJA fistulas and 6 cut‐surface leaks without intrahepatic bile duct dilatation. Two percutaneous therapeutic approaches were used: percutaneous transhepatic biliary drainage (PTBD) for fistula alone and PTBD with percutaneous drainage of biliary collection in patients with both complications. PTBD was successful in 21 cases (91.3%); the median delay from catheter insertion and leak resolution was 10.3 days (range: 7–41). The median maintenance of drainage was 14.8 days. In 1 patient, fistula recurrence after PTBD needed a surgical approach; after that, an anastomotic fistula was still found, and a new PTBD was successfully performed. In another patient, PTBD was immediately followed by retransplantation for portal vein thrombosis. There were no complications related to the interventional procedure. In conclusion, biliary fistulas after HJA in LT or after SLT can be successfully treated by PTBD. The absence of enlarged intrahepatic biliary ducts should not be a contraindication for percutaneous treatment. Liver Transpl 14:611–615, 2008. © 2008 AASLD.
Sharing views and interactions with single-user applications

Although work is frequently collaborative, most computer-based activities revolve around software packages designed to be used by one person at a time. To get around this, people working together often talk and gesture around a computer screen, perhaps taking turns interacting with the running “single-user” application by passing the keyboard around. However, it is technically possible to share these unaltered applications—even though they were originally designed for a single user only—across physically different workstations through special view-sharing software. Each person sees the same image of the running application on their own screen, and has an opportunity to interact with it by taking turns. This paper discusses the various roles and responsibilities of the view-sharing software that must be considered during its design and evaluation: view management, floor control, conference registration by participants, and handling of meta-level communications. A brief survey of existing shared view systems is provided for background.
The Value of Believing in Free Will

Does moral behavior draw on a belief in free will? Two experiments examined whether inducing participants to believe that human behavior is predetermined would encourage cheating. In Experiment 1, participants read either text that encouraged a belief in determinism (i.e., that portrayed behavior as the consequence of environmental and genetic factors) or neutral text. Exposure to the deterministic message increased cheating on a task in which participants could passively allow a flawed computer program to reveal answers to mathematical problems that they had been instructed to solve themselves. Moreover, increased cheating behavior was mediated by decreased belief in free will. In Experiment 2, participants who read deterministic statements cheated by overpaying themselves for performance on a cognitive task; participants who read statements endorsing free will did not. These findings suggest that the debate over free will has societal, as well as scientific and theoretical, implications.
Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation

The development of more complex in vitro models for the assessment of novel drugs and chemicals is needed because of the limited biological relevance of animal models to humans as well as ethical considerations. Although some human-cell-based assays exist, they are usually 2D, consist of single cell type, and have limited cellular and functional representation of the native tissue. In this study, we have used biomimetic porous electrospun scaffolds to develop an immunocompetent 3D model of the human respiratory tract comprised of three key cell types present in upper airway epithelium. The three cell types, namely, epithelial cells (providing a physical barrier), fibroblasts (extracellular matrix production), and dendritic cells (immune sensing), were initially grown on individual scaffolds and then assembled into the 3D multicell tissue model. The epithelial layer was cultured at the air–liquid interface for up to four weeks, leading to formation of a functional barrier as evidenced by an increase in transepithelial electrical resistance (TEER) and tight junction formation. The response of epithelial cells to allergen exposure was monitored by quantifying changes in TEER readings and by assessment of cellular tight junctions using immunostaining. It was found that epithelial cells cocultured with fibroblasts formed a functional epithelial barrier at a quicker rate than single cultures of epithelial cells and that the recovery from allergen exposure was also more rapid. Also, our data show that dendritic cells within this model remain viable and responsive to external stimulation as evidenced by their migration within the 3D construct in response to allergen challenge. This model provides an easy to assemble and physiologically relevant 3D model of human airway epithelium that can be used for studies aiming at better understanding lung biology, the cross-talk between immune cells, and airborne allergens and pathogens as well as drug delivery.
Regulation of Lef-mediated Transcription and p53-dependent Pathway by Associating β-Catenin with CBP/p300*

CBP and its homologue p300 play significant roles in cell differentiation, cell cycle, and anti-oncogenesis. We demonstrated that β-catenin, recently known as a potent oncogene, and CBP/p300 are associated through its CH3 region, which is a primary target of adenoviral oncoprotein E1A and various nuclear proteins, such as p53, cyclin E, and AP-1, and both are colocalized in the nuclear bodies. CBP/p300 potentiated Lef-mediated transactivation of β-catenin, and E1A, a potent inhibitor of CBP/p300, repressed its transactivation. Furthermore, overexpression of stable β-catenin mutant competitively suppressed the p53-dependent pathway. These may be a key mechanism of β-catenin involved in oncogenic events underlying disruption of tumor suppressor function through CBP/p300.
The Impact of Leadership Orientation on Strategic Information System Planning Processes, with an Application to Libyan Organizations

The planning stage in the development of an information system (IS) is important for IS/business alignment. Accordingly, academics and practitioners in both developed and developing countries are concerned about the impact of leadership orientation on strategic IS planning (SISP). The focus of this research is to identify the nature of the relationship between leadership orientations and IS planning approaches in the context of Libyan organizations. To investigate this relationship, a postal survey was conducted to collect data from 117 executives responsible for IS planning. The questionnaire asked about leadership values and SISP approaches using multi-item, multi-scaled questions. The results show that “controlling” and “competing” leadership orientations have a positive direct effect on all SISP approaches. Coordinator leadership orientations exhibited the highest positive association with rational, adaptable, and intuitive SISP approaches. The results of this research will have important implications for Libyan organizations, especially as they attempt to rebuild the country's economy after the Libyan revolution. These implications are discussed in detail in the paper.
External Constraints on Monetary Policy and the Financial Accelerator

We develop a small open economy macroeconomic model where financial conditions influence aggregate behavior. We use this model to explore the connection between the exchange rate regime and financial distress. We show that fixed exchange rates exacerbate financial crises by tieing the hands of the monetary authorities. We then investigate the quantitative significance by first calibrating the model to Korean data and then showing that it does a reasonably good job of matching the Korean experience during its recent financial crisis. In particular, the model accounts well for the sharp increase in lending rates and the large drop in output, investment and productivity during the 1997-1998 episode. We then perform some counterfactual exercises to illustrate the quantitative significance of fixed versus floating rates both for macroeconomic performance and for welfare. Overall, these exercises imply that welfare losses following a financial crisis are significantly larger under fixed exchange rates relative to flexible exchange rates.
Implementing Propensity Score Matching with Network Data: The effect of GATT on bilateral trade

Motivated by the evaluation of the causal effect of the General Agreement on Tariffs and Trade on bilateral international trade flows, we investigate the role of network structure in propensity score matching under the assumption of strong ignorability. We study the sensitivity of causal inference with respect to the presence of characteristics of the network in the set of confounders conditional on which strong ignorability is assumed to hold. We find that estimates of the average causal effect are highly sensitive to the presence of node-level network statistics in the set of confounders. Therefore, we argue that estimates may suffer from omitted variable bias when the relational dimension of units is ignored, at least in our application.
Dicyanovinyl and Cyano-Ester Benzoindolenine Squaraine Dyes: The Effect of the Central Functionalization on Dye-Sensitized Solar Cell Performance

In order to achieve a greater light absorption in the near-infrared (NIR) region with a panchromatic spectral response and to suppress the photo-isomerisation phenomenon, we herein report the design, synthesis, spectroscopic and electrochemical characterization of novel centrally functionalized symmetric benzoindolenine squaraine dyes. These molecules have shown different photoelectrical conversion properties, depending on the dicyanovinyl and cyano-ester group substitution on the squaric core unit and on the extension of the π-conjugation.
Gene finding with a hidden Markov model of genome structure and evolution

MOTIVATION A growing number of genomes are sequenced. The differences in evolutionary pattern between functional regions can thus be observed genome-wide in a whole set of organisms. The diverse evolutionary pattern of different functional regions can be exploited in the process of genomic annotation. The modelling of evolution by the existing comparative gene finders leaves room for improvement. RESULTS A probabilistic model of both genome structure and evolution is designed. This type of model is called an Evolutionary Hidden Markov Model (EHMM), being composed of an HMM and a set of region-specific evolutionary models based on a phylogenetic tree. All parameters can be estimated by maximum likelihood, including the phylogenetic tree. It can handle any number of aligned genomes, using their phylogenetic tree to model the evolutionary correlations. The time complexity of all algorithms used for handling the model are linear in alignment length and genome number. The model is applied to the problem of gene finding. The benefit of modelling sequence evolution is demonstrated both in a range of simulations and on a set of orthologous human/mouse gene pairs. AVAILABILITY Free availability over the Internet on www server: http://www.birc. dk/Software/evogene.
Mutagenesis and Modeling To Predict Structural and Functional Characteristics of the Staphylococcus aureus MepA Multidrug Efflux Pump

ABSTRACT MepA is a multidrug and toxin extrusion (MATE) family protein and the only MATE protein encoded within the Staphylococcus aureus genome. Structural data for MATE proteins are limited to a single high-resolution example, NorM of Vibrio cholerae. Substitution mutations were created in MepA using gradient plates containing both a substrate and reserpine as an efflux pump inhibitor. Site-directed mutagenesis of plasmid-based mepA was used to reproduce these mutations, as well as unique or low-frequency mutations identified in mepA-overexpressing clinical strains, and to mutagenize conserved acidic residues. The effect of these changes on protein function was quantitated in a norA-disrupted host strain by susceptibility testing with and without inhibitors and by determining the proficiency of ethidium efflux. Up-function substitutions clustered in the carboxy half of MepA, near the cytoplasmic face of the protein. Repeated application of the same gradient plate conditions frequently reproduced identical substitution mutations, suggesting that individual residues are required for interaction with specific substrates. Acidic residues critical to protein function were identified in helices 4 and 5. In silico modeling revealed an outward-facing molecule, with helices 1, 2, 4, 7, 8, and 10 having contact with a central cavity that may represent a substrate translocation pathway. Functionally important residues within this cavity included S81, A161, M291, and A302. These data provide a critical starting point for understanding how MATE multidrug efflux proteins function and will be useful in refining crystallographic data when they are available.
Optimal Gaussian Weight Predictor and Sorting Using Genetic Algorithm for Reversible Watermarking Based on PEE and HS

This paper introduces a reversible watermarking algorithm that exploits an adaptable predictor and sorting parameter customized for each image and each payload. Our proposed method relies on a wellknown prediction-error expansion (PEE) technique. Using small PE values and a harmonious PE sorting parameter greatly decreases image distortion. In order to exploit adaptable tools, Gaussian weight predictor and expanded variance mean (EVM) are used as parameters in this work. A genetic algorithm is also introduced to optimize all parameters and produce the best results possible. Our results show an improvement in image quality when compared with previous conventional works. key words: prediction-error expansion (PEE), histogram shifting (HS), reversible watermarking, Gaussian weight predictor, expanded variance mean (EVM)
Toxoplasmosis in prey species and consequences for prevalence in feral cats: not all prey species are equal

SUMMARY Toxoplasma gondii is largely transmitted to definitive felid hosts through predation. Not all prey species represent identical risks of infection for cats because of differences in prey susceptibility, exposure and/or lifespan. Previously published studies have shown that prevalence in rodent and lagomorph species is positively correlated with body mass. We tested the hypothesis that different prey species have different infection risks by comparing infection dynamics of feral cats at 4 sites in the sub-Antarctic Kerguelen archipelago which differed in prey availability. Cats were trapped from 1994 to 2004 and anti-T. gondii IgG antibodies were detected using the modified agglutination test (⩾1:40). Overall seroprevalence was 51·09%. Antibody prevalence differed between sites, depending on diet and also on sex, after taking into account the effect of age. Males were more often infected than females and the difference between the sexes tended to be more pronounced in the site where more prey species were available. A difference in predation efficiency between male and female cats may explain this result. Overall, our results suggest that the composition of prey items in cat diet influences the risk of T. gondii infection. Prey compositon should therefore be considered important in any understanding of infection dynamics of T. gondii.
Beyond tag relevance: integrating visual attention model and multi-instance learning for tag saliency ranking

Tag ranking has emerged as an important research topic recently due to its potential application on web image search. Conventional tag ranking approaches mainly rank the tags according to their relevance levels with respect to a given image. Nonetheless, such algorithms heavily rely on the large-scale image dataset and the proper similarity measurement to retrieve semantic relevant images with multi-labels. In contrast to the existing tag relevance ranking algorithms, in this paper, we propose a novel tag saliency ranking scheme, which aims to automatically rank the tags associated with a given image according to their saliency to the image content. To this end, this paper presents an integrated framework for tag saliency ranking which combines both visual attention model and multi-instance learning algorithm to investigate the saliency ranking order information of tags with respect to the given image. Specifically, tags annotated on the image-level are propagated to the region-level via an efficient multi-instance learning algorithm firstly; then, visual attention model is employed to measure the importance of regions in the given image. And finally, tags are ranked according to the saliency values of the corresponding regions. Experiments conducted on the COREL and MSRC image datasets demonstrate the effectiveness and efficiency of the proposed framework.
Social Tag Prediction Base on Supervised Ranking Model

Recently, social tag recommendation has gained more attention in web research, and many approaches were proposed, which can be classified into two types: rule-based and classification-based approaches. However, too much expert experience and manual work are needed in rule-based approaches, and its generalization is limited. Additionally, there are some essential barriers in classification-based approaches, since tag recommendation is transformed into a multiclasses classification problem, such as tag collection is not fixed. Different from them, ranking model is more suitable, in which supervised learning can be used. In additions, the whole tag recommendation task can be divided into 4 subtasks according to the existence of users and resources. In different subtasks, different features are constructed, in order that existed information can be used sufficiently. The experimental results show that the proposed supervised ranking model performs well on the training and test dataset of RSDC 2008 recovered by ourselves.