Miracle-dz/UniFAR-FTUs huggingface dataset:
Rights protection for relational data

we introduce a solution for relational database content rights protection through watermarking. Rights protection for relational data is of ever-increasing interest, especially considering areas where sensitive, valuable content is to be outsourced. A good example is a data mining application, where data is sold in pieces to parties specialized in mining it. Different avenues are available, each with its own advantages and drawbacks. Enforcement by legal means is usually ineffective in preventing theft of copyrighted works, unless augmented by a digital counterpart, for example, watermarking. While being able to handle higher level semantic constraints, such as classification preservation, our solution also addresses important attacks, such as subset selection and random and linear data changes. We introduce wmdb. , a proof-of-concept implementation and its application to real-life data, namely, in watermarking the outsourced Wal-Mart sales data that we have available at our institute.
A CMOS Voltage Reference Based on Mutual Compensation of Vtn and Vtp

A novel temperature-stable nonbandgap voltage reference, which is compatible with standard CMOS technology, is presented in this brief. No diodes or parasitic bipolar transistors are used. Based on mutual temperature compensation of the threshold voltages of nMOS and pMOS transistors, a temperature-insensitive voltage reference with significant reduction in temperature dependence of mobility is achieved without using subthreshold characteristics. The problem of a fixed voltage reference value is also avoided by different parameter design. Experimental results of the proposed voltage reference implemented with a 0.35-μm CMOS process demonstrate that the output of the voltage reference is 847.5 mV, a temperature coefficient of 11.8 ppm/°C with a temperature range from 0 °C to 130 °C is obtained at 3-V power supply, a power-supply noise attenuation of 72 dB is achieved without any filtering capacitor, and the line regulation is better than 0.185 mV/V from 1.8-V to 4.5-V supply voltage dissipating a maximum supply current of 8 μA. The active area of the presented voltage reference is 90 μm ×120 μm.
Potencies of Cocaine Methiodide on Major Cocaine Targets in Mice

Cocaine methiodide (CM), a charged cocaine analog, cannot pass the blood brain barrier. It has been assumed the effects of systemic CM represent cocaine actions in peripheral tissues. However, the IC50 values of CM have not been clearly determined for the major cocaine targets: dopamine, norepinephrine, and serotonin transporters, and sodium channels. Using cells transfected with individual transporters from mice and synaptosomes from mouse striatum tissues, we observed that the inhibition IC50 values for monoamine uptake by CM were 31-fold to 184-fold higher compared to cocaine at each of the transporters. In dorsal root ganglion neurons, cocaine inhibited sodium channels with an apparent IC50 of 75 µM, while CM showed no observable effect at concentrations up to 3 mM. These results indicate that an equal dose of CM will not produce an equivalent peripheral effect of cocaine.
Episodic Short-Term Recognition Requires Encoding into Visual Working Memory: Evidence from Probe Recognition after Letter Report

Human vision is organized in discrete processing episodes (e.g., eye fixations or task-steps). Object information must be transmitted across episodes to enable episodic short-term recognition: recognizing whether a current object has been seen in a previous episode. We ask whether episodic short-term recognition presupposes that objects have been encoded into capacity-limited visual working memory (VWM), which retains visual information for report. Alternatively, it could rely on the activation of visual features or categories that occurs before encoding into VWM. We assessed the dependence of episodic short-term recognition on VWM by a new paradigm combining letter report and probe recognition. Participants viewed displays of 10 letters and reported as many as possible after a retention interval (whole report). Next, participants viewed a probe letter and indicated whether it had been one of the 10 letters (probe recognition). In Experiment 1, probe recognition was more accurate for letters that had been encoded into VWM (reported letters) compared with non-encoded letters (non-reported letters). Interestingly, those letters that participants reported in their whole report had been near to one another within the letter displays. This suggests that the encoding into VWM proceeded in a spatially clustered manner. In Experiment 2, participants reported only one of 10 letters (partial report) and probes either referred to this letter, to letters that had been near to it, or far from it. Probe recognition was more accurate for near than for far letters, although none of these letters had to be reported. These findings indicate that episodic short-term recognition is constrained to a small number of simultaneously presented objects that have been encoded into VWM.
The effect of flooding on mental health: Lessons learned for building resilience

Risk management and climate adaptation literature focuses mainly on reducing the impacts of, exposure to, and vulnerability to extreme events such as floods and droughts. Posttraumatic stress disorder is one of the most important impacts related to these events, but also a relatively under‐researched topic outside original psychopathological contexts. We conduct a survey to investigate the mental stress caused by floods. We focus on hydrological, individual, and collective drivers of posttraumatic stress. We assess stress with flood‐specific health scores and the GHQ‐12 General Health Questionnaire. Our findings show that the combination of water depth and flood velocity measured via a Hazard Class Index is an important stressor; and that mental health resilience can be significantly improved by providing the population with adequate information. More specifically, the paper shows that psychological distress can be reduced by (i) coordinating awareness of flood risks and flood protection and prevention behavior; (ii) developing the ability to protect oneself from physical, material and intangible damage; (iii) designing simple insurance procedures and protocols for fast recovery; and (iv) learning from previous experiences.
Health Literacy-Related Knowledge, Attitude, and Perceived Barriers: A Cross-sectional Study among Physicians, Pharmacists, and Nurses in Public Hospitals of Penang, Malaysia

Introduction Patients’ health literacy (HL) has emerged as a critical determinant of health outcomes and becoming one of the core competencies of health-care providers. Therefore, this study aimed to assess among Malaysian physicians, pharmacists, and nurses, their HL-related knowledge, attitude, and perceived barriers, and also to determine the associated factors. Methods A cross-sectional study design was used to enroll 600 eligible respondents using stratified sampling from 6 public hospitals in Penang, Malaysia. A validated self-administered questionnaire was used for data collection. Descriptive and inferential analysis was performed with statistical significance defined as p < 0.05. Results The response rate was 87.6% with 526 questionnaires completed. Of these, 34.2% had poor knowledge, and more than half had negative attitude (51.9%) toward HL with no significant differences among physicians, pharmacists, and nurses. The majority of the respondents perceived time constraints and lack of human resources as major HL barriers. Respondents who had heard the term or concept of HL had significantly higher level of knowledge (p < 0.001) and more positive attitude (p < 0.001). While longer service years (≥11 years) significantly contribute to the higher level of HL knowledge among health-care providers (p = 0.028). Conclusion The study findings supported the concern on inadequate knowledge and substantially negative attitude toward HL among study health-care providers with highest cited barriers were time constraint and human resources. Thus, efforts to improve their perspective about HL to be effective patient educators are highly advocated.
Efficacy of yoga for vasomotor symptoms: a randomized controlled trial

ObjectiveThis study aims to determine the efficacy of yoga in alleviating vasomotor symptoms (VMS) frequency and bother. MethodsThis study was a three-by-two factorial, randomized controlled trial. Eligible women were randomized to yoga (n = 107), exercise (n = 106), or usual activity (n = 142), and were simultaneously randomized to a double-blind comparison of &ohgr;-3 fatty acid (n = 177) or placebo (n = 178) capsules. Yoga intervention consisted of 12 weekly 90-minute yoga classes with daily home practice. Primary outcomes were VMS frequency and bother assessed by daily diaries at baseline, 6 weeks, and 12 weeks. Secondary outcomes included insomnia symptoms (Insomnia Severity Index) at baseline and 12 weeks. ResultsAmong 249 randomized women, 237 (95%) completed 12-week assessments. The mean baseline VMS frequency was 7.4 per day (95% CI, 6.6 to 8.1) in the yoga group and 8.0 per day (95% CI, 7.3 to 8.7) in the usual activity group. Intent-to-treat analyses included all participants with response data (n = 237). There was no difference between intervention groups in the change in VMS frequency from baseline to 6 and 12 weeks (mean difference [yoga − usual activity] from baseline at 6 wk, −0.3 [95% CI, −1.1 to 0.5]; mean difference [yoga − usual activity] from baseline at 12 wk, −0.3 [95% CI, −1.2 to 0.6]; P = 0.119 across both time points). Results were similar for VMS bother. At week 12, yoga was associated with an improvement in insomnia symptoms (mean difference [yoga − usual activity] in the change in Insomnia Severity Index, 1.3 [95% CI, −2.5 to −0.1]; P = 0.007). ConclusionsAmong healthy women, 12 weeks of yoga class plus home practice, compared with usual activity, do not improve VMS frequency or bother but reduce insomnia symptoms.
Variations in the Sun’s Meridional Flow over a Solar Cycle

Solar Meridional Flow The surface of the Sun is composed of plasma that exhibits observable flow patterns. The weakest flow pattern occurs along meridional lines from the equator toward the poles. Hathaway and Rightmire (p. 1350) measured the meridional flow using observations taken with the Michelson Doppler Imager onboard the Solar and Heliospheric Observatory between 1996 and 2009 and found that meridional flow varied with the solar cycle, such that flow was faster during the 2004–2009 minimum than during the 1996–1997 minimum. This finding provides further evidence that the last solar minimum was peculiar by comparison with previous cycles. Observed variations in the Sun’s poleward flow have consequences for models and predictions of the solar cycle. The Sun’s meridional flow is an axisymmetric flow that is generally directed from its equator toward its poles at the surface. The structure and strength of the meridional flow determine both the strength of the Sun’s polar magnetic field and the intensity of sunspot cycles. We determine the meridional flow speed of magnetic features on the Sun using data from the Solar and Heliospheric Observatory. The average flow is poleward at all latitudes up to 75°, which suggests that it extends to the poles. It was faster at sunspot cycle minimum than at maximum and substantially faster on the approach to the current minimum than it was at the last solar minimum. This result may help to explain why this solar activity minimum is so peculiar.
Technical Efficiency of Mexico’s Public Health System in the Delivery of Obstetric Care, during 2012–2018

The objective of this study was to evaluate the technical efficiency of Mexico’s public health system in the delivery of obstetric care from 2012 to 2018. A multi-stage quantitative study of the public health institutions responsible for 95% of the system’s obstetric services was conducted using data envelopment analysis. The efficiency of state-level productive units (decision-making units, or DMUs) was calculated and juxtaposed with the DMUs’ maximum (0.82) and minimum (0.22) scores. Using the outcomes of the initial stage, the average technical efficiency of each institution at the national level was estimated and compared. The results were also utilized to estimate and compare the average efficiency of each state-level health system based on economic characteristics (state GDP per capita). Outputs included prenatal visits and deliveries, while inputs comprised gynecologists, exam rooms, and delivery rooms. Institutional efficiency ranged from 0.16 to 0.82, with an average of 0.417. The Ministry of Health (0.82) and the Mexican Social Security Institute (0.747) exhibited the highest efficiency scores, while the remaining institutions (Institute for Social Security and Services for State Workers [ISSSTE]; Mexican Petroleum [PEMEX]; the Secretary of National Defense [SEDENA]; and the Navy [SEMAR]) scored below the health system average. Of the 153 DMUs, 20% surpassed the maximum (0.82) and 40.6% fell below the minimum (0.22). These findings indicate that 80% of DMUs have unused operational capacity that could be utilized to enhance technical efficiency. No relationship was found between efficiency and the GDP of Mexico’s 32 politico-administrative divisions. The efficiency gap between institutions (0.66) shows that while some DMUs are saturated (exhibiting high efficiency scores), the majority have unused operational capacity. Leveraging this untapped capacity could address the needs of vulnerable populations facing restricted access due to health system fragmentation.
SAT-Based Bounded Model Checking for Weighted Deontic Interpreted Systems (Extended Abstract)

We present WECTL∗KD, a weighted branching time temporal logic to specify knowledge, and correct functioning behaviour in multi-agent systems (MAS). We interpret the formulae of the logic over models generated by weighted deontic interpreted systems (WDIS). Furthermore, we investigate a SAT-based bounded model checking (BMC) technique for WDIS and for WECTL∗KD.
Main processes of bone formation and regeneration through molecules and cells as biostimulators in buccomaxillofacial surgery: a systematic review

Introduction: At a cellular and molecular level, tissue engineering offers numerous advantages that meet the needs of the injured tissue or organ for the bone regeneration process in buccomaxillofacial surgeries. To achieve this, it is necessary to understand the chemical, physical, and biological processes of both the biological material and the target biological niche. Objective: It was to carry out a concise systematic review of the main processes of bone formation and regeneration using molecules and cells as biostimulators in buccomaxillofacial surgeries. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from December 2023 to February 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 182 articles were found, 60 articles were evaluated in full and 36 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 12 studies with a high risk of bias and 20 studies that did not meet GRADE and AMSTAR-2. Most studies did not show homogeneity in their results, with X2=54.7%>50%. The bone regeneration process occurs through the activation of osteoblasts and vascular control guided by PDGFs and TGF-β. These growth factors also promote matrix formation and osteoblast differentiation. Some biodegradable natural polymers (chitosan®) associated with inorganic materials such as tricalcium phosphate were tested as spongy carriers for PDGF-BB. Chitosan® has been attributed to hemostatic properties, inducing bone formation and regulating the release of bioactive agents. The use of platelet-rich plasma and mesenchymal stem cells (exosomes and microRNAs) has been indicated and used in other areas of oral and buccomaxillofacial surgery, accelerating a process of bone regeneration that normally already occurs and this process continues its path until the formation of bone mature.
Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus

Genome-wide association studies (GWAS) are identifying genetic predisposition to various diseases. The 17q24.3 locus harbors the single nucleotide polymorphism (SNP) rs1859962 that is statistically associated with prostate cancer (PCa). It defines a 130-kb linkage disequilibrium (LD) block that lies in an ∼2-Mb gene desert area. The functional biology driving the risk associated with this LD block is unknown. Here, we integrate genome-wide chromatin landscape data sets, namely, epigenomes and chromatin openness from diverse cell types. This identifies a PCa-specific enhancer within the rs1859962 risk LD block that establishes a 1-Mb chromatin loop with the SOX9 gene. The rs8072254 and rs1859961 SNPs mapping to this enhancer impose allele-specific gene expression. The variant allele of rs8072254 facilitates androgen receptor (AR) binding driving increased enhancer activity. The variant allele of rs1859961 decreases FOXA1 binding while increasing AP-1 binding. The latter is key to imposing allele-specific gene expression. The rs8072254 variant in strong LD with the rs1859962 risk SNP can account for the risk associated with this locus, while rs1859961 is a rare variant less likely to contribute to the risk associated with this LD block. Together, our results demonstrate that multiple genetic variants mapping to a unique enhancer looping to the SOX9 oncogene can account for the risk associated with the PCa 17q24.3 locus. Allele-specific recruitment of the transcription factors androgen receptor (AR) and activating protein-1 (AP-1) account for the increased enhancer activity ascribed to this PCa-risk LD block. This further supports the notion that an integrative genomics approach can identify the functional biology disrupted by genetic risk variants.
Isolated OB Associations in Stripped H I Gas Clouds

HST ACS HRC images in UV (F250W), V (F555W), and I (F814W) resolve three isolated OB associations that lie up to 30 kpc from the stellar disk of the S0 galaxy NGC 1533. Previous narrowband Hα imaging and optical spectroscopy showed these objects as unresolved intergalactic H II regions having Hα luminosities consistent with single early-type O stars. These young stars lie in stripped H I gas with column densities ranging from 1.5 to 2.5 × 1020 cm−2 and velocity dispersions near 30 km s−1. Using the HST broadband colors and magnitudes along with previously determined Hα luminosities, we place limits on the masses and ages of each association, considering the importance of stochastic effects for faint (MV > − 8) stellar populations. The upper limits to their stellar masses range from 600 to 7000 M☉, and ages range from 2 to 6 Myr. This analysis includes an updated calculation of the conversion factor between the ionizing luminosity and the total number of main-sequence O stars contained within an H II region. The photometric properties and sizes of the isolated associations and other objects in the HRC fields are consistent with those of Galactic stellar associations, open clusters, and/or single O and B stars. We interpret the age-size sequence of associations and clustered field objects as an indication that these isolated associations are most likely rapidly dispersing. Furthermore, we consider the possibility that these isolated associations represent the first generation of stars in the H I ring surrounding NGC 1533. This work suggests star formation in the unique environment of a galaxy’s outermost gaseous regions proceeds similarly to that within the Galactic disk and that star formation in tidal debris may be responsible for building up a younger halo component.
Intermediate divergence levels maximize the strength of structure–sequence correlations in enzymes and viral proteins

Structural properties such as solvent accessibility and contact number predict site‐specific sequence variability in many proteins. However, the strength and significance of these structure–sequence relationships vary widely among different proteins, with absolute correlation strengths ranging from 0 to 0.8. In particular, two recent works have made contradictory observations. Yeh et al. (Mol. Biol. Evol. 31:135–139, 2014) found that both relative solvent accessibility (RSA) and weighted contact number (WCN) are good predictors of sitewise evolutionary rate in enzymes, with WCN clearly out‐performing RSA. Shahmoradi et al. (J. Mol. Evol. 79:130–142, 2014) considered these same predictors (as well as others) in viral proteins and found much weaker correlations and no clear advantage of WCN over RSA. Because these two studies had substantial methodological differences, however, a direct comparison of their results is not possible. Here, we reanalyze the datasets of the two studies with one uniform analysis pipeline, and we find that many apparent discrepancies between the two analyses can be attributed to the extent of sequence divergence in individual alignments. Specifically, the alignments of the enzyme dataset are much more diverged than those of the virus dataset, and proteins with higher divergence exhibit, on average, stronger structure–sequence correlations. However, the highest structure–sequence correlations are observed at intermediate divergence levels, where both highly conserved and highly variable sites are present in the same alignment.
LocaTag - An NFC-Based System Enhancing Instant Messaging Tools with Real-Time User Location

In recent years instant messaging tools have been successfully introduced to support communication and collaboration processes in work environments. Research suggests that the use of instant messaging tools lead to an increased feeling of connectedness, social presence and awareness within a collaborative group. Consequently, the goal of our research is to improve communication and collaboration within a group through automated and real-time dissemination of presence information, using instant messaging software. The paper describes LocaTag, a system that enhances instant messaging tools with real-time location information through the use of NFC enabled mobile devices. The LocaTag application is implemented as a prototype system that provides the Skype instant messaging application with automated status messages, reflecting the current location of a user. This location information is derived from a NFC-tag based check-in/-out routine incorporating the mobile phone of the user. The tie-in of NFC based location information and existing, broadly used instant messaging applications is an approach towards the real-timed is semination of presence information in collaborative groups. Its technical feasibility, limitations and future research approaches are discussed in this manuscript.