Miracle-dz/UniFAR-FTUs huggingface dataset:
Small intestinal diverticulum with bleeding

Rationale: Small intestinal diverticulum with bleeding is an important reason for obscure gastrointestinal bleeding (OGB) , in addition to tumor and vascular diseases. Small intestinal diverticulum with bleeding is difficult to detect by barium meal and angiographic methods and has been regarded as an important cause of obscure gastrointestinal tract bleeding in adolescents. Because of its complicated etiology and non-specific clinical manifestations, it is relatively difficult to detect small intestinal diverticulum with bleeding, especially in patients with a large amount of bleeding and hemodynamic instability. Patient concerns: This retrospective study collects clinical statistics of 19 patients admitted to our hospital from January 2010 to December 2016. Patients who had small intestinal diverticulum patients with bleeding were included in this study. Patients who were taking anticoagulants were excluded Diagnoses: Small intestinal diverticulum patients with bleeding. Interventions: This retrospective study describes the clinical features of patients with small intestinal diverticulum whose main symptom was gastrointestinal bleeding and analyze the literature on this topic, with particular reference to the clinical characteristics, pathological features, and choice of examination methods. Lessons: Small intestinal diverticulum with bleeding is a common cause of obscure gastrointestinal bleeding, but it is difficult to detect using normal examination methods. For patients with repeated gastrointestinal bleeding and no positive results found on gastroscopy and colonoscopy, endoscopy of the small intestine and CTE with contrast can be considered as a diagnostic modality.
Top-down Modulations in the Visual Form Pathway Revealed with Dynamic Causal Modeling

Perception entails interactions between activated brain visual areas and the records of previous sensations, allowing for processes like figure–ground segregation and object recognition. The aim of this study was to characterize top-down effects that originate in the visual cortex and that are involved in the generation and perception of form. We performed a functional magnetic resonance imaging experiment, where subjects viewed 3 groups of stimuli comprising oriented lines with different levels of recognizable high-order structure (none, collinearity, and meaning). Our results showed that recognizable stimuli cause larger activations in anterior visual and frontal areas. In contrast, when stimuli are random or unrecognizable, activations are greater in posterior visual areas, following a hierarchical organization where areas V1/V2 were less active with “collinearity” and the middle occipital cortex was less active with “meaning. ” An effective connectivity analysis using dynamic causal modeling showed that high-order visual form engages higher visual areas that generate top-down signals, from multiple levels of the visual hierarchy. These results are consistent with a model in which if a stimulus has recognizable attributes, such as collinearity and meaning, the areas specialized for processing these attributes send top-down messages to the lower levels to facilitate more efficient encoding of visual form.
Assessment of embedded fiber Bragg gratings for structural health monitoring of composites

This work provides a system-level investigation into the use of embedded fiber Bragg grating optical sensors as a viable sensing architecture for the structural health monitoring of composite structures. The practical aspects of the embedding process are documented for both carbon fiber–reinforced polymer and glass fiber–reinforced polymer structures manufactured by both oven vacuum bag and vacuum-assisted resin transfer method processes. Initially, embedded specimens were subject to long-term water submersion to verify performance in an underwater environment. A larger, more complex jointed specimen was also fabricated with a fully embedded sensor network of fiber Bragg gratings and subjected to incrementally induced bearing damage. Using commercially available interrogation hardware, a damage detection structural health monitoring algorithm was developed and deployed. The results permit statistically precise detection of low levels of connection damage in the composite specimen.
Subtle Distinctions: How Attentional Templates Influence EEG Parameters of Cognitive Control in a Spatial Cuing Paradigm

Using event-related potentials (ERPs) of the electroencephalogram, we investigated how cognitive control is altered by the scope of an attentional template currently activated in visual working memory. Participants performed a spatial cuing task where an irrelevant color singleton cue was presented prior to a target array. Blockwise, the target was either a red circle or a gray square and had to be searched within homogenous (gray circles) or heterogeneous non-targets (differently colored circles or various shapes). Thereby we aimed to trigger the adoption of different attentional templates: a broader singleton or a narrower, more specific feature template. ERP markers of attentional selection and inhibitory control showed that the amount of cognitive control was overall enhanced when participants searched on the basis of a feature-specific template: the analysis revealed reduced selection (N2pc, frontal P2) and pronounced inhibition (negative shift of frontal N2) of the irrelevant color cue when participants searched for a feature target. On behavioral level attentional capture was most pronounced in the color condition with no differentiation between the task-induced scopes of the attentional template.
Individual Identification and Genetic Variation of Lions (Panthera leo) from Two Protected Areas in Nigeria

This survey was conducted in two protected areas in Nigeria to genetically identify individual lions and to determine the genetic variation within and between the populations. We used faecal sample DNA, a non-invasive alternative to the risky and laborious task of taking samples directly from the animals, often preceded by catching and immobilization. Data collection in Yankari Game Reserve (YGR) spanned through a period of five years (2008 –2012), whereas data in Kainji Lake National Park (KLNP) was gathered for a period of three years (2009, 2010 and 2012). We identified a minimum of eight individuals (2 males, 3 females, 3 unknown) from YGR and a minimum of ten individuals (7 males, 3 females) from KLNP. The two populations were found to be genetically distinct as shown by the relatively high fixation index (FST = 0.17) with each population exhibiting signs of inbreeding (YGR FIS = 0.49, KLNP FIS = 0.38). The genetic differentiation between the Yankari and Kainji lions is assumed to result from large spatial geographic distance and physical barriers reducing gene flow between these two remaining wild lion populations in Nigeria. To mitigate the probable inbreeding depression in the lion populations within Nigeria it might be important to transfer lions between parks or reserves or to reintroduce lions from the zoos back to the wild.
Paracervical Block for Pain Control in First-Trimester Surgical Abortion: A Randomized Controlled Trial

OBJECTIVE: Despite lack of efficacy data, the majority of first-trimester surgical abortions are performed with a paracervical block. Women may be unnecessarily exposed to a painful injection and potentially noxious medication. Our objective was to estimate the effect of a paracervical block and the effect of gestational age on patient pain perception. METHODS: This was a randomized, single-blind trial of patients undergoing abortion receiving paracervical block or sham stratified by gestational age (early: less than 8 weeks of gestation, n=60; late: 8–10 6/7 weeks of gestation, n=60). Premedicated with ibuprofen and lorazepam, all participants received 2 mL 1% buffered lidocaine injected at the tenaculum site followed by a slow, deep injection of 18 mL at four sites (block) or no injection (sham) with a 3-minute wait. The primary outcome was dilation pain (100-mm visual analog scale). Secondary outcomes included pain at additional time points, satisfaction, need for more analgesics, and adverse events. RESULTS: Full enrollment occurred (n=120). We used intent-to-treat analysis. Demographics did not differ between groups. Paracervical block administration was painful (mean 55 mm compared with sham 30 mm, P<.001) but decreased dilation pain (42 mm compared with 79 mm, P<.001) and aspiration pain (63mm compared with 89 mm, P<.001). These results were consistent for both gestational age strata; however, paracervical block benefit was greater at an earlier gestation. Satisfaction scores with pain control and the procedure were significantly higher in the block group. CONCLUSION: Although paracervical block is painful, it reduces first-trimester abortion pain regardless of gestational age, but the benefit on dilation pain was greater at earlier gestations. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials. gov, NCT01094366. LEVEL OF EVIDENCE: I
Balanced Fluid Versus Saline-Based Fluid in Post-operative Severe Traumatic Brain Injury Patients: Acid-Base and Electrolytes Assessment.

Background Normal saline (NS) is a common fluid of choice in neurosurgery and neuro-intensive care unit (ICU), but it does not contain other electrolytes and has the potential to cause hyperchloremic metabolic acidosis with prolonged infusion. These problems may be reduced with the availability of balanced fluid (BF), which becomes a more physiological isotonic solution with the presence of complete electrolyte content. This study aimed to compare the changes in electrolytes and acid-base between NS and BF (Sterofundin® ISO) therapy for post-operative severe traumatic brain injury (TBI) patients in neuro-ICU. Methods Sixty-six severe TBI patients who required emergency craniotomy or craniectomy and were planned for post-operative ventilation were randomised into NS (n = 33) and BF therapy groups (n = 33). The calculation of maintenance fluid given was based on the Holliday-Segar method. The electrolytes and acid-base parameters were assessed at an 8 h interval for 24 h. The data were analysed using repeated measures ANOVA. Results The NS group showed a significant lower base excess (-3.20 versus -1.35, P = 0.049), lower bicarbonate level (22.03 versus 23.48 mmol/L, P = 0.031), and more hyperchloremia (115.12 versus 111.74 mmol/L, P < 0.001) and hypokalemia (3.36 versus 3.70 mmol/L, P < 0.001) than the BF group at 24 h of therapy. The BF group showed a significantly higher level of calcium (1.97 versus 1.79 mmol/L, P = 0.003) and magnesium (0.94 versus 0.80 mmol/L, P < 0.001) than the NS group at 24 h of fluid therapy. No significant differences were found in pH, pCO2, lactate, and sodium level. Conclusion BF therapy showed better effects in maintaining higher electrolyte parameters and reducing the trend toward hyperchloremic metabolic acidosis than the NS therapy during prolonged fluid therapy for postoperative TBI patients.
Thermal Aware Test Scheduling for NTV Circuit

Although the near threshold voltage (NTV) design has achieved energy efficiency, certain challenges remain regarding its application. In this paper, we describe the analysis of thermally induced reliability concern in test process. In an NTV environment, the thermal dependency of a circuit delay is changed, and a difference in thermal constraints from that in a nominal voltage design exists. In addition, we propose a new test scheduling method for NTV circuits that alleviates the thermal constraints in system-on-chip test processes. Our simulation results show that the test time could be reduced while minimizing the reliability loss.
Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa

Objective: To estimate time from HIV infection to linkage-to-care and its determinants. Linkage-to-care is usually assessed using the date of HIV diagnosis as the starting point for exposure time. However, timing of diagnosis is likely endogenous to linkage, leading to bias in linkage estimation. Design: We used longitudinal HIV serosurvey data from a large population-based HIV incidence cohort in KwaZulu-Natal (2004–2013) to estimate time of HIV infection. We linked these data to patient records from a public-sector HIV treatment and care program to determine time from infection to linkage (defined using the date of the first CD4+ cell count). Methods: We used Cox proportional hazards models to estimate time from infection to linkage and the effects of the following covariates on this time: sex, age, education, food security, socioeconomic status, area of residence, distance to clinics, knowledge of HIV status, and whether other household members have initiated antiretroviral therapy. Results: We estimated that it would take an average of 4.9 years for 50% of HIV seroconverters to be linked to care (95% confidence intervals: 4.2–5.7). Among all cohort members who were linked to care, the median CD4+ cell count at linkage was 350 cells/&mgr;l (95% confidence interval: 330–380). Men and participants aged less than 30 years were found to have the slowest rates of linkage-to-care. Time to linkage became shorter over calendar time. Conclusion: Average time from HIV infection to linkage-to-care is long and needs to be reduced to ensure that HIV treatment-as-prevention policies are effective. Targeted interventions for men and young individuals have the largest potential to improve linkage rates.
Like bees around the hive: a comparative study of a mobile augmented reality map

We present findings from field trials of MapLens, a mobile augmented reality (AR) map using a magic lens over a paper map. Twenty-six participants used MapLens to play a location-based game in a city centre. Comparisons to a group of 11 users with a standard 2D mobile map uncover phenomena that arise uniquely when interacting with AR features in the wild. The main finding is that AR features facilitate place-making by creating a constant need for referencing to the physical, and in that it allows for ease of bodily configurations for the group, encourages establishment of common ground, and thereby invites discussion, negotiation and public problem-solving. The main potential of AR maps lies in their use as a collaborative tool.
Overview of the Distribution, Habitat Association and Impact of Exotic Ants on Native Ant Communities in New Caledonia

Ants are among the most ubiquitous and harmful invaders worldwide, but there are few regional studies of their relationships with habitat and native ant communities. New Caledonia has a unique and diverse ant fauna that is threatened by exotic ants, but broad-scale patterns of exotic and native ant community composition in relation to habitat remain poorly documented. We conducted a systematic baiting survey of 56 sites representing the main New Caledonian habitat types: rainforest on ultramafic soils (15 sites), rainforest on volcano-sedimentary soils (13), maquis shrubland (15), Melaleuca-dominated savannas (11) and Acacia spirorbis thickets (2). We collected a total of 49 species, 13 of which were exotic. Only five sites were free of exotic species, and these were all rainforest. The five most abundant exotic species differed in their habitat association, with Pheidole megacephala associated with rainforests, Brachymyrmex cf. obscurior with savanna, and Wasmannia auropunctata and Nylanderia vaga present in most habitats. Anoplolepis gracilipes occurred primarily in maquis-shrubland, which contrasts with its rainforest affinity elsewhere. Multivariate analysis of overall ant species composition showed strong differentiation of sites according to the distribution of exotic species, and these patterns were maintained at the genus and functional group levels. Native ant composition differed at invaded versus uninvaded rainforest sites, in the absence of differences in habitat variables. Generalised Myrmicinae and Forest Opportunists were particularly affected by invasion. There was a strong negative relationship between the abundance of W. auropunctata and native ant abundance and richness. This emphasizes that, in addition to dominating many ant communities numerically, some exotic species, and in particular W. auropunctata, have a marked impact on native ant communities.
Modeling Decisions in Games Using Reinforcement Learning

Reinforcement-learning (RL) algorithms have been used to model human decisions in different decision-making tasks. Recently, certain deep RL algorithms have been proposed; however, there is little research that compares deep RL algorithms with traditional RL algorithms in accounting for human decisions. The primary objective of this paper is to compare deep and traditional RL algorithms in a virtual environment concerning their performance, learning speed, ability to account for human decisions, and ability to extract features from the decision environment. We implemented traditional RL algorithms like imitation learning, Q-Learning, and a deep RL algorithm, DeepQ Learning, to train an agent for playing a platform jumper game. For model comparison, we collected human data from 15 human players on the platform jumper game. As part of our evaluation, we also increased the speed of the moving platform in the jumper game to test how humans and model agents responded to the changing game conditions. Results showed that DeepQ approach took more training episodes than the traditional RL algorithms to learn the gameplay. However, the DeepQ algorithm could extract features directly from images of gameplay; whereas, other algorithms had to be fed the extracted features. Furthermore, conventional algorithms performed more human-like in a slow version of the game; however, the DeepQ algorithm performed more humanlike in the fast version of the game.
Activation of TGF‐β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease

The etiology and mechanisms for inflammatory bowel disease (IBD) are incompletely known. Determination of new, clinically important mechanisms for intestinal inflammation is imperative for developing effective therapies to treat IBD. We sought to define a widespread mechanism for colon mucosal inflammation via the activation of TGF‐β activated Kinase 1 (TAK1), a central regulator of cellular inflammatory actions. Activation of TAK1 and the downstream inflammatory signaling mediators was determined in pediatric patients with ulcerative colitis (UC) or Crohn's disease (CD) as well as in DSS‐induced and spontaneous IBD in mice. The role of TAK1 in facilitating intestinal inflammation in murine models of IBD was investigated by using (5Z)‐7‐Oxozeaenol, a highly selective pharmacological inhibitor of TAK1. We found hyper‐activation of TAK1 in patients with UC or CD and in murine models of IBD. Pharmacological inhibition of TAK1 prevented loss in body weight, disease activity, microscopic histopathology, infiltration of inflammatory cells in the colon mucosa, and elevated proinflammatory cytokine production in two murine models of IBD. We demonstrated that at the early phase of the disease activation of TAK1 is restricted in the epithelial cells. However, at a more advanced stage of the disease, TAK1 activation predominantly occurs in nonepithelial cells, especially in macrophages. These findings elucidate the activation of TAK1 as crucial in promoting intestinal inflammation. Thus, the TAK1 activation pathway may represent a suitable target to design new therapies for treating IBD in humans.
Effect of single annealing on microstructure and mechanical properties of BTi-6431S titanium alloy

The effects of single annealing on the microstructure and mechanical properties of BTi-6431S titanium alloy were studied by OM,EPMA and tensile test.The results show that,with increasing annealing temperature,the primary α phase becomes coarse,then changes into equiaxed shape,and its volume fraction decreases gradually,while the volume fractions of β phase and secondary α phase increase.With elevating the annealing temperature,the room temperature strength increases at first and then decreases,while the high temperature strength increases gradually,but the room-temperature and high-temperature ductility decreases.After annealing at 980 ℃,BTi-6431S alloy acquires good strength at high-temperature and plasticity at room-temperature.The ultimate tensile strength at 650 ℃ can reach more than 600 MPa,and the room-temperature elongation is more than 8%.
Genetic Analysis of Invasive Aedes albopictus Populations in Los Angeles County, California and Its Potential Public Health Impact

The Asian tiger mosquito, Aedes albopictus, is an anthropophilic aggressive daytime-biting nuisance and an efficient vector of certain arboviruses and filarial nematodes. Over the last 30 years, this species has spread rapidly through human travel and commerce from its native tropical forests of Asia to every continent except Antarctica. In 2011, a population of Asian tiger mosquito (Aedes albopictus) was discovered in Los Angeles (LA) County, California. To determine the probable origin of this invasive species, the genetic structure of the population was compared against 11 populations from the United States and abroad, as well as preserved specimens from a 2001 introduction into California using the mitochondrial cytochrome c oxidase 1 (CO1) gene. A total of 66 haplotypes were detected among samples and were divided into three main groups. Aedes albopictus collected in 2001 and 2011 from LA County were genetically related and similar to those from Asia but distinct from those collected in the eastern and southeastern United States. In view of the high genetic similarities between the 2001 and 2011 LA samples, it is possible that the 2011 population represents in part the descendants of the 2001 introduction. There remains an imperative need for improved surveillance and control strategies for this species.
The Impact of the Transportation Network Companies on the Taxi Industry: Evidence from Beijing’s GPS Taxi Trajectory Data

To gain insight into how transportation network companies, such as Uber and Didi, impact the taxi industry, we conduct a multi-period analysis of taxi drivers’ behaviors, based on GPS trajectory data collected from three time periods in Beijing, i.e., November 2012, November 2014, and November 2015. We extract both passenger-delivery and passenger-searching trip information from GPS trajectories and compare the spatial, temporal, densification, and poolability properties of taxi trips in different time periods. Our results reveal that the taxi industry was adversely influenced by the competition between transportation network companies; as compared with that of 2012, the average passenger-delivery trip number per day per taxi dropped by 18.08% and the average daily profit per taxi dropped by 19.29% in the year 2015, respectively. We also compare passenger-searching strategies, passenger-delivery strategies, and service area preferences between taxi drivers with top and bottom efficiency in different time periods. We find that compared with drivers with lower efficiency, drivers with high efficiency tend to search locally, have a higher delivery speed, and serve more often within the inner part of Beijing.