Miracle-dz/UniFAR-FTUs huggingface dataset:
Spectrum sharing and resource allocation for energy-efficient heterogeneous cognitive radio networks with femtocells

In heterogeneous wireless networks with femtocells, the issue of interference between femtocells and macrocells should be carefully considered. Using cognitive radio for interference management is a promising technique in heterogeneous wireless networks with femtocells. In this paper, we study the energy efficiency aspect of spectrum sharing and resource allocation in heterogeneous wireless networks with femtocells and cognitive radios. We use the price of interference to model the interference between femtocells and macrocells. We formulate the problem of interference management and power allocation as a Stackelberg game. In addition, an iteration algorithm based on price updating is proposed to obtain the Stackelberg equilibrium solution to the resource allocation problem for energy efficiency. Simulation results are presented to show that the proposed scheme can improve energy efficiency significantly in heterogeneous wireless networks with femtocells and cognitive radios.
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

Polymerase I and transcript release factor (PTRF)/Cavin is a cytoplasmic protein whose expression is obligatory for caveola formation. Using biochemistry and fluorescence resonance energy transfer–based approaches, we now show that a family of related proteins, PTRF/Cavin-1, serum deprivation response (SDR)/Cavin-2, SDR-related gene product that binds to C kinase (SRBC)/Cavin-3, and muscle-restricted coiled-coil protein (MURC)/Cavin-4, forms a multiprotein complex that associates with caveolae. This complex can constitutively assemble in the cytosol and associate with caveolin at plasma membrane caveolae. Cavin-1, but not other cavins, can induce caveola formation in a heterologous system and is required for the recruitment of the cavin complex to caveolae. The tissue-restricted expression of cavins suggests that caveolae may perform tissue-specific functions regulated by the composition of the cavin complex. Cavin-4 is expressed predominantly in muscle, and its distribution is perturbed in human muscle disease associated with Caveolin-3 dysfunction, identifying Cavin-4 as a novel muscle disease candidate caveolar protein.
Temporal-nasal asymmetry of rapid orienting to face-like stimuli

Recent work suggests that a subcortical visual route may mediate rapid orienting towards faces in the visual periphery. We now demonstrate that this orienting bias towards faces shows a temporal-nasal visual field asymmetry of responses, supporting the view that it is mediated by extrageniculate pathways. Upright schematic face-like pattern elicited faster behavioural responses than inverted one in the temporal but not in the nasal hemifield of each eye. This effect occurred for saccades but not for manual responses. The presence of a similar asymmetry of the orienting bias in newborns supports the role of extrageniculate pathways in face detection in both neonates and adults.
Mechanisms of abrupt climate change of the last glacial period

More than a decade ago, ice core records from Greenland revealed that the last glacial period was characterized by abrupt climate changes that recurred on millennial time scales. Since their discovery, there has been a large effort to determine whether these climate events were a global phenomenon or were just confined to the North Atlantic region and also to reveal the mechanisms that were responsible for them. In this paper, we review the available paleoclimate observations of abrupt change during the last glacial period in order to place constraints on possible mechanisms. Three different mechanisms are then reviewed: ocean thermohaline circulation, sea ice feedbacks, and tropical processes. Each mechanism is tested for its ability to explain the key features of the observations, particularly with regard to the abruptness, millennial recurrence, and geographical extent of the observed changes. It is found that each of these mechanisms has explanatory strengths and weaknesses, and key areas in which progress could be made in improving the understanding of their long‐term behavior, both from observational and modeling approaches, are suggested. Finally, it is proposed that a complete understanding of the mechanisms of abrupt change requires inclusion of processes at both low and high latitudes, as well as the potential for feedbacks between them. Some suggestions for experimental approaches to test for such feedbacks with coupled climate models are given.
Binary Constraint Preserving Graph Matching

Graph matching is a fundamental problem in computer vision and pattern recognition area. In general, it can be formulated as an Integer Quadratic Programming (IQP) problem. Since it is NP-hard, approximate relaxations are required. In this paper, a new graph matching method has been proposed. There are three main contributions of the proposed method: (1) we propose a new graph matching relaxation model, called Binary Constraint Preserving Graph Matching (BPGM), which aims to incorporate the discrete binary mapping constraints more in graph matching relaxation. Our BPGM is motivated by a new observation that the discrete binary constraints in IQP matching problem can be represented (or encoded) exactly by a l2-norm constraint. (2) An effective projection algorithm has been derived to solve BPGM model. (3) Using BPGM, we propose a path-following strategy to optimize IQP matching problem and thus obtain a desired discrete solution at convergence. Promising experimental results show the effectiveness of the proposed method.
Outcome of panic and depression in a seven‐year follow‐up: results of the Zurich study

ABSTRACT— In this study, the association and outcome of panic and depression were investigated in an epidemioloeical cohort of young adults interviewed at age 21, 23, and 28. The prevalence rates of sporadic panic, panic disorder, major depression, and recurrent brief depression were very stable. There was a clear preponderance of females in all diagnoses. Panic and depression overlapped to a large extent cross‐sectionally at all 3 interviews, and this overlap increased in a longitudinal perspective. For the analysis of outcome, the subjects were divided into 4 groups according to their diagnosis at the first interview: pure panic, pure depression, mixed panic and depression, and controls. Irrespective of the first diagnosis, the 7‐year outcome showed a strong tendency to develop into pure depression or mixed panic and depression at follow‐up interviews. In a longitudinal perspective, cases that suffered from both panic and depression appeared more severely ill, as expressed in very high treatment rates and a high rate of lifetime suicide attempts.
High voltage single-ended DC-DC converter

A new energy transfer system is evaluated for application in a 130 watt, l800 volt dc to dc converter. The single-ended half-wave transformer-coupled converter provides high efficiency (82%) with a low component count in the power train, resulting in a 25% cost reduction relative to a push-pull pulse-width controlled converter.
Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention

Book file PDF easily for everyone and every device. You can download and read online Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention file PDF Book only if you are registered here. And also you can download or read online all Book PDF file that related with Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention book. Happy reading Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention Bookeveryone. Download file Free Book PDF Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention at Complete PDF Library. This Book have some digital formats such us :paperbook, ebook, kindle, epub, fb2 and another formats. Here is The Complete PDF Book Library. It's free to register here to get Book file PDF Adolescent Health: A Multidisciplinary Approach to Theory, Research, and Intervention.
The BarA-UvrY Two-Component System Regulates Virulence in Avian Pathogenic Escherichia coli O78:K80:H9

ABSTRACT The BarA-UvrY two-component system (TCS) in Escherichia coli is known to regulate a number of phenotypic traits. Both in vitro and in vivo assays, including the chicken embryo lethality assay, showed that this TCS regulates virulence in avian pathogenic E. coli (APEC) serotype O78:K80:H9. A number of virulence determinants, such as the abilities to adhere, invade, persist within tissues, survive within macrophages, and resist bactericidal effects of serum complement, were compromised in mutants lacking either the barA or uvrY gene. The reduced virulence was attributed to down regulation of type 1 and Pap fimbriae, reduced exopolysaccharide production, and increased susceptibility to oxidative stress. Our results indicate that BarA-UvrY regulates virulence properties in APEC and that the chicken embryo lethality assay can be used as a surrogate model to determine virulence determinants and their regulation in APEC strains.
Challenges in the management of chronic noncommunicable diseases by Indonesian community pharmacists

Objectives: We explored factors influencing Indonesian primary care pharmacists’ practice in chronic noncommunicable disease management and proposed a model illustrating relationships among factors. Methods: We conducted in-depth, semistructured interviews with pharmacists working in community health centers (Puskesmas, n=5) and community pharmacies (apotek, n=15) in East Java Province. We interviewed participating pharmacists using Bahasa Indonesia to explore facilitators and barriers to their practice in chronic disease management. We audiorecorded all interviews, transcribed ad verbatim, translated into English and analyzed the data using an approach informed by “grounded-theory”. Results: We extracted five emergent themes/factors: pharmacists’ attitudes, Puskesmas/apotek environment, pharmacy education, pharmacy professional associations, and the government. Respondents believed that primary care pharmacists have limited roles in chronic disease management. An unfavourable working environment and perceptions of pharmacists’ inadequate knowledge and skills were reported by many as barriers to pharmacy practice. Limited professional standards, guidelines, leadership and government regulations coupled with low expectations of pharmacists among patients and doctors also contributed to their lack of involvement in chronic disease management. We present the interplay of these factors in our model. Conclusion: Pharmacists’ attitudes, knowledge, skills and their working environment appeared to influence pharmacists’ contribution in chronic disease management. To develop pharmacists’ involvement in chronic disease management, support from pharmacy educators, pharmacy owners, professional associations, the government and other stakeholders is required. Our findings highlight a need for systematic coordination between pharmacists and stakeholders to improve primary care pharmacists’ practice in Indonesia to achieve continuity of care.
Glucose Uptake in Trichoderma harzianum: Role of gtt1

ABSTRACT Using a differential display technique, the gene gtt1, which codes for a high-affinity glucose transporter, has been cloned from the mycoparasite fungus Trichoderma harzianum CECT 2413. The deduced protein sequence of the gtt1 gene shows the 12 transmembrane domains typical of sugar transporters, together with certain residues involved in glucose uptake, such as a conserved arginine between domains IV and V and an aromatic residue (Phe) in the sequence of domain X. The gtt1 gene is transcriptionally regulated, being repressed at high levels of glucose. When carbon sources other than glucose are utilized, gtt1 repression is partially alleviated. Full derepression of gtt1 is obtained when the fungus is grown in the presence of low carbon source concentrations. This regulation pattern correlates with the role of this gene in glucose uptake during carbon starvation. Gene expression is also controlled by pH, so that the gtt1 gene is repressed at pH 6 but not at pH 3, a fact which represents a novel aspect of the influence of pH on the gene expression of transporters. pH also affects glucose transport, since a strongly acidic pH provokes a 40% decrease in glucose transport velocity. Biochemical characterization of the transport shows a very low Km value for glucose (12 μM). A transformant strain that overexpresses the gtt1 gene shows a threefold increase in glucose but not galactose or xylose uptake, a finding which confirms the role of the gtt1 gene in glucose transport. The cloning of the first filamentous ascomycete glucose transporter is the first step in elucidating the mechanisms of glucose uptake and carbon repression in aerobic fungi.
Analysis of the moderating effect of industry on online behaviour

Purpose – The main objective of the current work is to analyse the importance of the moderating effect of industry type on technological firms' behaviour and on the acceptance of online business management applications.Design/methodology/approach – The conceptual model, based on a technology acceptance model (TAM), has been tested across structural equation modelling techniques. Thus, a multi‐sample analysis has been developed to study the significance of the effect on industry. Data were collected using e‐mail and post‐mail survey.Findings – The findings show that there are several factors influencing the acceptance process, such as ease of use and usefulness, but their effect depends on the industry in which the organisation operates. Likewise, greater experience in technology – which is the case for some sectors – facilitates the acceptance of IT.Research limitations/implications – Managers should be aware that the synergies gained through their economic activity must be applied to adopt more new onlin.
OpenCL-based design methodology for application-specific processors

OpenCL is a programming language standard which enables the programmer to express the application by structuring its computation as kernels. The OpenCL compiler is given the explicit freedom to parallelize the execution of kernel instances at all the levels of parallelism. In comparison to the traditional C programming language which is sequential in nature, OpenCL enables higher utilization of parallelism naturally available in hardware constructs while still having a feasible learning curve for engineers familiar with the C language. This paper describes methodology and compiler techniques involved in applying OpenCL as an input language for a design flow of application-specific processors. At the core of the methodology is a whole program optimizing compiler that links together the host and kernel codes of the input OpenCL program and parallelizes the result on a customized statically scheduled processor. The OpenCL vendor extension mechanism is used to provide clean access to custom operations. The methodology is studied with a design case to verify the scalability of the implementation at the instruction level and to exemplify the use of custom operations. The case shows that the use of OpenCL allows producing scalable application-specific processor designs and makes it possible to gradually reach the performance of hand-tailored RTL designs by exploiting the OpenCL extension mechanism to access custom hardware operations of varying complexity.
Determinants of nondisclosure of HIV status among women attending the prevention of mother to child transmission programme, Makonde district, Zimbabwe, 2009

Introduction The 2007 United Nations General Assembly Report on HIV/AIDS in Zimbabwe reported nondisclosure of HIV status as a challenge in the PMTCT programme. Preliminary investigations on nondisclosure among 21 women tested for HIV at Chinhoyi Hospital showed that only six had disclosed their HIV status. We investigated the determinants of nondisclosure of HIV status. Methods A cross sectional analytic study was conducted at six health facilities in Makonde district. The Theory of Planned Behaviour was adapted to guide socio-cultural variables assessed. Antenatal and postnatal women tested for HIV in the PMTCT program who consented to participate were interviewed. Results We enrolled 334 women. Thirty four percent (114) did not disclose their HIV status. Among HIV positive respondents, 43% (25) did not disclose their status. Women who believed disclosure caused physical abuse (OR=1.81, 95% CI: 1.17-2.90), caused divorce (OR=2.01, 95% CI: 1.25-3.22) and was unimportant (OR= 2.26, 95% CI: 1.33-3.87) were two times less likely to disclose their status. Respondents who received group HIV pre-test counselling were 2.4 times more likely not to disclose. Receiving ANC HIV education at least twice and referral for psychosocial support were significantly protective [OR 0.54 (95% CI 0.24-0.63) and 0.16 (95% CI: 0.06-0.41) respectively. Independent determinants of nondisclosure among HIV positive women were perception that disclosure would cause divorce (AOR=7.82, p=0.03), living with an extended family (AOR=10.3, p=0.01) and needing spousal approval of HIV testing (AOR= 0.11, p<0.001). Conclusion Lack of psychosocial support and counselling for women and belief that disclosure causes divorce, abuse or is unimportant contributes to nondisclosure. Identifying women with social challenges and strengthening their referral for psychosocial support can improve disclosure of HIV status and reduce mother to child transmission of HIV.
Traumatic Brain Injuries during Development: Implications for Alcohol Abuse

Traumatic brain injuries are strongly related to alcohol intoxication as by some estimates half or more of all brain injuries involve at least one intoxicated individual. Additionally, there is mounting evidence that traumatic brain injuries can themselves serve as independent risk factors for the development of alcohol use disorders, particularly when injury occurs during juvenile or adolescent development. Here, we will review the epidemiological and experimental evidence for this phenomenon and discuss potential psychosocial mediators including attenuation of negative affect and impaired decision making as well as neurochemical mediators including disruption in the glutamatergic, GABAergic, and dopaminergic signaling pathways and increases in inflammation.
Reference Gene Selection for Real-Time Quantitative PCR Analysis of the Mouse Uterus in the Peri-Implantation Period

The study of uterine gene expression patterns is valuable for understanding the biological and molecular mechanisms that occur during embryo implantation. Real-time quantitative RT-PCR (qRT-PCR) is an extremely sensitive technique that allows for the precise quantification of mRNA abundance; however, selecting stable reference genes suitable for the normalization of qRT-PCR data is required to avoid the misinterpretation of experimental results and erroneous analyses. This study employs several mouse models, including an early pregnancy, a pseudopregnancy, a delayed implantation and activation, an artificial decidualization and a hormonal treatment model; ten candidate reference genes (PPIA, RPLP0, HPRT1, GAPDH, ACTB, TBP, B2M, 18S, UBC and TUBA) that are found in uterine tissues were assessed for their suitability as internal controls for relative qRT-PCR quantification. GeNormPLUS, NormFinder, and BestKeeper were used to evaluate these candidate reference genes, and all of these methods identified RPLP0 and GAPDH as the most stable candidates and B2M and 18S as the least stable candidates. However, when the different models were analyzed separately, the reference genes exhibited some variation in their expression levels.
Latent Topic Models for Hypertext

Latent topic models have been successfully applied as an unsupervised topic discovery technique in large document collections. With the proliferation of hypertext document collection such as the Internet, there has also been great interest in extending these approaches to hypertext [6, 9]. These approaches typically model links in an analogous fashion to how they model words - the document-link co-occurrence matrix is modeled in the same way that the document-word co-occurrence matrix is modeled in standard topic models. In this paper we present a probabilistic generative model for hypertext document collections that explicitly models the generation of links. Specifically, links from a word w to a document d depend directly on how frequent the topic of w is in d, in addition to the in-degree of d. We show how to perform EM learning on this model efficiently. By not modeling links as analogous to words, we end up using far fewer free parameters and obtain better link prediction results.
Moral Relativism: A Short Introduction

On September 11 2001, thousands of people died in the attacks on the United States. How could this act of terror be justified? A young man kills his sister to protect his family's honour. How could this be "right"? These are just two of the questions tackled by Neil Levy in this guide to the philosophy of moral relativism - the idea that concepts of "rightness" and "wrongness" vary from culture to culture and that there is no such thing as an absolute moral code. Opening with a comprehensive definition to this controversial theory, the book examines all the arguments for and against moral relativism, from its implications for ethics to the role of human biology and the difficulty of separating cultural values from innate behaviour. The author draws on case studies from sources as diverse as the Aztecs and the Australian aboriginals to illustrate debates such as: can we ever have a shared morality? ; can concepts of "rightness" and "wrongness" ever be absolute? ; does moral relativism pose a threat to human rights? Concluding with a proposal for a more modest form of relativism, and outlining all the key reading in this area, this introduction should prove enlightening for students and general readers alike.
Factors associated with clinic non‐attendance in adults with Type 1 diabetes mellitus

In order to examine the causes of non‐attendance in a diabetic clinic, a 1‐year retrospective casenote review of 259 diabetic patients with no evidence of major complications was undertaken. Frequency of clinic attendance, clinic non‐attendance, and glycaemic control (HbA1c) were recorded. In a sub‐sample of 82 patients, more detailed demographic data was obtained via questionnaire. During the previous year 39 % of patients had failed to attend the clinic on at least one occasion and 10 % were recurrent non‐attenders. Non‐attenders had a significantly higher mean HbA1c compared with those who did attend (8.1 ± 2.2 vs 7.6 ± 1.6 %; p = 0.03). They were also significantly younger (mean age 27 ± 7 vs 29 ± 9 yrs; p = 0.02) and had a significantly shorter duration of diabetes (12 ± 8 vs 15 ± 10 yrs; p = 0.02). Attendance did not differ according to gender or age of onset of diabetes. Sub‐sample analysis showed that smokers, those with children at home, and single parents were all more likely to default from their appointments. Non‐attendance is a significant problem at our diabetic clinic, however, by addressing the reasons why patients fail to attend clinic we hope to develop strategies to encourage regular attendance. This may be translated into improved glycaemic control and ultimately reduce the risk of late diabetic complications. © 1998 John Wiley & Sons, Ltd.