Miracle-dz/UniFAR-FTUs huggingface dataset:
Depression and the Metabolic Syndrome in Young Adults: Findings From the Third National Health and Nutrition Examination Survey

Objective: Previous reports have suggested that depression may lead to the development of cardiovascular disease through its association with the metabolic syndrome; however, little is known about the relationship between depression and the metabolic syndrome. The aim of this study was to establish an association between depression and the metabolic syndrome in a nationally representative sample. Methods: The Third National Health and Nutrition Examination Survey is a population-based health survey of noninstitutionalized US citizens completed between 1988 and 1994. Three thousand one hundred eighty-six men and 3003 women, age 17 to 39, free of coronary heart disease and diabetes, completed the depression module from the Diagnostic Interview Schedule and a medical examination that provided clinical data needed to establish the presence of the metabolic syndrome, as defined by the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Cholesterol in Adults. Results: Women with a history of a major depressive episode were twice as likely to have the metabolic syndrome compared with those with no history of depression. The relationship between depression and metabolic syndrome remained after controlling for age, race, education, smoking, physical inactivity, carbohydrate consumption, and alcohol use. Men with a history of depression were not significantly more likely to have the metabolic syndrome. Conclusions: The prevalence of the metabolic syndrome is elevated among women with a history of depression. It is important to better understand the role depression may play in the effort to reduce the prevalence of the metabolic syndrome and its health consequences.
Criminalising Cartels: Australia's Slow Conversion

Australia is set to become the latest in a growing number of countries to join the United States’ “coalition of the willing” with respect to the criminalisation of serious cartel conduct. However, there are emerging questions as to whether criminalisation has sufficient support amongst key stakeholders in countries outside of the United States so as to guarantee its effective implementation. This article argues that for any new criminal regime to be successful in deterring serious cartel conduct such support, from the regulator, government, business sector, general public, judiciary and academia, will be vital. It considers the extent to which cartel criminalisation enjoys the support of each of these groups currently in Australia and finds that with the exception of the regulator and the new government, it may be questionable, at best. The findings reported in the article provide insight into the impetus for, and process of, the criminalisation initiative in Australia and have important practical consequences for the effectiveness of the future regime. Of international concern, they also suggest the need for caution in assuming the successful exportation of the American model of anti–cartel law enforcement.
Thirty-day hospital readmission following discharge from postacute rehabilitation in fee-for-service Medicare patients.

IMPORTANCE The Centers for Medicare & Medicaid Services recently identified 30-day readmission after discharge from inpatient rehabilitation facilities as a national quality indicator. Research is needed to determine the rates and factors related to readmission in this patient population. OBJECTIVE To determine 30-day readmission rates and factors related to readmission for patients receiving postacute inpatient rehabilitation. DESIGN, SETTING, AND PATIENTS Retrospective cohort study of records for 736,536 Medicare fee-for-service beneficiaries (mean age, 78.0 [SD, 7.3] years) discharged from 1365 inpatient rehabilitation facilities to the community in 2006 through 2011. Sixty-three percent of patients were women, and 85.1% were non-Hispanic white. MAIN OUTCOMES AND MEASURES Thirty-day readmission rates for the 6 largest diagnostic impairment categories receiving inpatient rehabilitation. These included stroke, lower extremity fracture, lower extremity joint replacement, debility, neurologic disorders, and brain dysfunction. RESULTS Mean rehabilitation length of stay was 12.4 (SD, 5.3) days. The overall 30-day readmission rate was 11.8% (95% CI, 11.7%-11.8%). Rates ranged from 5.8% (95% CI, 5.8%-5.9%) for patients with lower extremity joint replacement to 18.8% (95% CI, 18.8%-18.9%). for patients with debility. Rates were highest in men (13.0% [ 95% CI, 12.8%-13.1%], vs 11.0% [95% CI, 11.0%-11.1%] in women), non-Hispanic blacks (13.8% [95% CI, 13.5%-14.1%], vs 11.5% [95% CI, 11.5%-11.6%] in whites, 12.5% [95% CI, 12.1%-12.8%] in Hispanics, and 11.9% [95% CI, 11.4%-12.4%] in other races/ethnicities), beneficiaries with dual eligibility (15.1% [95% CI, 14.9%-15.4%], vs 11.1% [95% CI, 11.0%-11.2%] for no dual eligibility), and in patients with tier 1 comorbidities (25.6% [95% CI, 24.9%-26.3%], vs 18.9% [95% CI, 18.5%-19.3%] for tier 2, 15.1% [95% CI, 14.9%-15.3%] for tier 3, and 9.9% [95% CI, 9.9%-10.0%] for no tier comorbidities). Higher motor and cognitive functional status were associated with lower hospital readmission rates across the 6 impairment categories. Adjusted readmission rates by state ranged from 9.2% to 13.6%. Approximately 50% of patients rehospitalized within the 30-day period were readmitted within 11 days of discharge. Medicare Severity Diagnosis-Related Group codes for heart failure, urinary tract infection, pneumonia, septicemia, nutritional and metabolic disorders, esophagitis, gastroenteritis, and digestive disorders were common reasons for readmission. CONCLUSIONS AND RELEVANCE Among postacute rehabilitation facilities providing services to Medicare fee-for-service beneficiaries, 30-day readmission rates ranged from 5.8% to 18.8% for selected impairment groups. Further research is needed to understand the causes of readmission.
Pediatric procedural sedation with ketamine: time to discharge after intramuscular versus intravenous administration.

OBJECTIVES Ketamine is an attractive agent for pediatric procedural sedation. There are limited data on time to discharge comparing intramuscular (IM) vs. intravenous (IV) ketamine. The authors set out to determine whether IM or IV ketamine leads to quicker discharge from the emergency department (ED) and how side effect profiles compare. METHODS All patients who had received ketamine IM or IV at a tertiary children's hospital ED during the 3-year study period (2004-2007) were identified. Prospective sedation registry data, retrospective medical records, and administrative data were reviewed for drug dosages, use of additional agents, time of drug administration to discharge, total ED time (triage to discharge), and adverse events. A subgroup analysis for patients requiring five or fewer sutures (short suture group) was performed. RESULTS A total of 229 patients were enrolled (60% male) with median age of 2.8 years (IQR =1.8-4.3 years) and median weight of 15.7 kg (range = 8.7-74 kg). Ketamine was most frequently employed for laceration repair (80%) and foreign body removal (9%). Overall, 48% received ketamine IM and 52% received it IV. In the short-suture subgroup, 52% received ketamine IM, while 48% received it IV. Multivariate linear regression analysis determined time from drug administration to patient discharge as 21 minutes shorter for IV compared with IM administration, adjusted for age and number of additional doses (R(2) = -0.35; 95% CI = -0.5 to -0.19; p < 0.001). Total time in the ED (triage to discharge) comparing IV versus IM administration, adjusting for age and gender and number of additional doses, was not significantly different (p = 0.16). In the short-suture subgroup, time to discharge from administration was also shorter in the IV ketamine group (R(2) = -0.454; 95%CI = -0.66 to -0.25; p < 0.001) but similar for total time in ED (p = 0.16). Overall, adverse events occurred in 35% (95% CI = 27% to 45%) of the IM group and 20% (95% CI = 13% to 28%) of the IV group (p = 0.01). Only one patient required brief bag-mask ventilation. CONCLUSIONS In this institution, time from drug injection to discharge was shorter in the IV compared to IM ketamine group, both overall and for the short-suture group. However, time from triage to discharge was similar.
Transportation Oil Demand Consumer Preferences and Asymmetric Price Responses: Some UK Evidence

The aim of this paper is to (i) establish the role of asymmetric price decompositions in UK road transportation fuel demand, (ii) make explicit the impact of the underlying energy demand trend and (iii) disaggregate the estimation for gasoline and diesel demand as separate commodities. Dynamic UK transport oil demand functions are estimated using the Seemingly Unrelated Structural Time Series Model with decomposed prices to allow for asymmetric price responses. The importance of starting with a flexible modelling approach that incorporates both an underlying demand trend and asymmetric price response function is highlighted. Furthermore, these features can lead to different insights and policy implications than might arise from a model without them. As an example, a zero elasticity for a price-cut is found (for both gasoline and diesel) implying that price reductions do not induce demand for road transportation fuel in the UK. The paper illustrates the importance of joint modelling of gasoline and diesel demand incorporating both asymmetric price responses and stochastic underlying energy demand trends.
Entrepreneurship education and context

Recently the importance of context and, in particular, the regional context and its function in shaping entrepreneurial capital, that is, the knowledge and skills as well as resources needed to start and grow ventures has been highlighted (Kotey 2006; Drakopoulou Dodd and Hynes 2012). Given this increasing interest, our intention in this special issue is to highlight the role context has to play in entrepreneurship education, which is a key input to the development of appropriate knowledge and skills. For many commentators the power of entrepreneurship and its importance in maintaining a growing and thriving economy remains unquestionable (Mitra 2008; Dutta, Li, and Merenda 2011; Liñán, Rodrı́guez-Cohard, and Rueda-Cantuche 2011; Raposo and do Paço 2011). Indeed, the implicit or explicit link between entrepreneurship and economic growth is evident in a variety of contexts and at different levels – international, national, regional and local (Minnitti 2008). For instance, at the European level, Bosma, Schutjens, and Stam (2009, 59) note that the goal of the EU 2000 Lisbon Agenda, for the EU, to become the world’s most innovative area by 2010 was based on the entrepreneurial power of its regions, while in cities entrepreneurial initiatives have been introduced to address economic issues (Tretten and Welter 2007). The interest in the connection between entrepreneurship and economic development has not been confined only to the domain of entrepreneurship but is also evident in related fields such as economics and geography (Drakopoulou Dodd and Hynes 2012). In the economic growth literature, for example, there is increasing focus on the relationship between entrepreneurship, sustainable regional development and competitive advantage: after all, ‘regional competitiveness and effective entrepreneurship are two sides of the same coin’ (Nijkamp 2009, 1). Entrepreneurial ventures help to maintain the economic vitality of a nation in a variety of ways including opportunity recognition, generation of new business ideas, economic activities, value creation and employment generation (Dutta, Li, and Merenda 2011, 163). However, it is not just economic ills for which entrepreneurship has been recommended as a panacea. Along with establishing a dynamic smalland medium-sized enterprise (SME) sector it is now considered to be a vital factor in
Changes in Gut Microbial Ecology and Immunological Responses of Mice Fed the Insoluble Fraction of Brassica rapa L. that was Fermented or Not

We aimed to investigate the effects of feeding fermented Brassica rapa L. on ecological and immunological changes in the mouse gut using in vitro cultivation tests and in vivo experiments in normal mice. In the preliminary in vitro study, two B. rapa L. products from different fermentation periods (one d [SF] or six months [LF]) were evaluated along with non-fermented vegetables (NF). Among the components of each product, the insoluble fraction resulted in the most prominent change such as a relative increase in butyrate production during a cultivation inoculated with mouse cecum contents. Based on this result, the boiled water-insoluble fractions of B. rapa L. (SF, LF, and NF samples) were selected as test materials for the subsequent in vivo experiment. Male C57BL/6J mice were divided into four groups and fed either a control diet (CON) or control diet plus one of the insoluble fractions for two weeks. The NF and LF groups had higher relative populations of Faecalibacterium prausnitzii than the CON group. Therefore, colonic butyrate concentrations were higher in the NF and LF groups than in the CON group. The oral administration of B. rapa L. extract induced immune regulatory effects, even when mice were fed NF and SF, but not LF, as assessed by an increase in regulatory T cell numbers. Our results indicate that feeding a purified insoluble fraction from B. rapa L. affects enteric short-chain fatty acid production and immunological responses in the mouse gut in a similar manner, regardless of the fermentation status.
Corporate Volunteering: Benefits and Challenges for Nonprofits

In the frame of corporate social responsibility, corporate volunteering is almost exclusively studied from the point of view of companies, while the perspectives of nonprofit organizations are neglected. Hence, this article focuses on the perspective of managers of nonprofit organizations on volunteer partnership projects with for-profit companies. In the center of this article lie nonprofit managers' strategy and motivation for participating in corporate volunteering, conception of corporate volunteer activities, and the often-cited win-win-win aspect. Key findings suggest that a majority of the questioned nonprofits lack strategic behavior and management tools for undertaking volunteer partnership projects with companies. Nevertheless, corporate volunteering is widely perceived as an opportunity and a promising method of raising donations for nonprofit organizations. This article suggests that the key to successful future cooperation between nonprofits and profit-oriented organizations lies in the processes of internal evaluation and subsequent strategy development.
Assessing and Teaching Team Leadership Capabilities: Field Testing a Behavioral Roles Approach with Business Undergraduate Students

Using the two-factor (task and social) model of team leadership, a course-based educational program designed to assess and improve student skills was empirically evaluated with 247 undergraduates at an urban regional campus of a Midwestern state university. Major findings revealed: (1) a statistically significant increase in mean overall team leadership scores of 20%, (2) statistically significant improvements in eight of ten specific task leadership roles and three of six social leadership roles, and (3) no substantive or practically significant differences in student improvement as a function of sex, age, race/ethnicity, or major.
Minds and hearts : exploring the teacher's role as a leader of pupils in a class.

This study is concerned with the particular role of the teacher as a leader of pupils in a class, a legislated requirement for teachers in South Africa since 1996. Literature and research have focussed attention regarding leadership in education on the principal, school governing body and school management team, and more recently distributed leadership in schools. This study, in contrast, seeks to concentrate on the leadership of teachers as they teach classes of pupils. A review of the current leadership literature applicable, in my view, to the practice of leadership in schools, provided the opportunity for the development of a theoretical framing for the study around the categories of leaders knowing, doing, being and relating. Teachers from eight Section 21 (state-aided, previously advantaged and currently well-resourced) schools in the greater Ethekweni region of KwaZulu-Natal, South Africa were selected for the study. They were observed in their teaching and interviewed to interrogate their understanding and performance as leaders, and to establish how and why leadership occurred or did not occur. Sampling for the four teachers who were observed in their teaching was purposive to establish levels of understanding, and enactment of leadership amongst advantaged teachers teaching in well resourced schools. These teachers were recommended for selection for this study by their principals, as teachers who had previously – in the opinion of the principals, evidenced leadership in their teaching. Forty three other teachers were interviewed in focus groups and film stimulus focus groups to view, consider and comment on teacher leadership behaviours in selected feature films – providing a vehicle for identifying how leadership occurs in teachers’ classes and what it is that teachers understand about leadership. Insights into the reason for teachers exercising leadership in a class were gained from consideration of the character and the competence of teachers, the circumstances under which leadership occurs and the nature of ‘called’ leaders with a sense of identity. The occurrences that caused the teachers to lead without any apparent training for leadership are examined in the light of the fact that these were selected teachers from well resourced schools who had all enjoyed growing and educational advantage. Their learning about leadership had been a largely unconscious occurrence in their lives. They did not know that they knew about leadership in teaching. The study firstly provides explanation of the phenomenon of leadership occurrence and understanding by teachers, who deny training in leadership and are not even aware of policy dictating that role for teachers insight and secondly, a new understanding of the relevant nature of the leadership practised by the teachers observed, and finally presents argument on the symbiotic nature of teaching and leading. This develops the thesis of the study; when teachers teach, they lead – to teach is to lead. It is recognised that the majority of teachers in South Africa will…
BIR2 affects complex formation of BAK1 with ligand binding receptors in plant defense

BAK1 is a multifunctional leucine-rich repeat receptor kinase (LRR-RLK) that exerts its function by interacting with multiple ligand binding receptors and thereby influences diverse processes varying from brassinosteroid perception via PAMP and DAMP perception to cell death control. We recently identified a new BAK1 interacting protein, BIR2, that is also a LRR-RLK. In contrast to BAK1, BIR2 negatively regulates BAK1-dependent PAMP responses. While brassinosteroid responses are not affected by BIR2, cell death is negatively regulated as described for BAK1. BIR2 is released from BAK1 after ligand perception, increasing the pool of free BAK1 that is available to form complexes with activated ligand binding receptors. Individual ligands can only partially release BAK1 from BIR2. After exposition to a cocktail of ligands, almost the complete amount of BAK1 can be released indicating that BAK1 exists, together with BIR2, in subpools that can be individually addressed by specific ligands. These data support the idea that BAK1 exists in preformed complexes with its ligand binding receptor partners. Overexpression of BIR2 results in reduced complex formation of BAK1 with FLS2, showing that BIR2 negatively regulates BAK1 complex formation with ligand binding receptors.
Remembering or knowing: electrophysiological evidence for an episodic memory deficit in schizophrenia

Background. In schizophrenia, impaired conscious retrieval of past events and facts may represent a selective cognitive deficit of declarative memory against a background of a generalized neuropsychological impairment. We aimed to disentangle the neural subprocesses leading to this deficit applying the ‘Remember/Know procedure’. Method. Event-related potentials (ERPs) were recorded as 14 schizophrenic patients and 14 controls recognized an equal mixture of previously presented old and new words. For recognized old words, participants were required to judge whether recognition was associated with recollection (‘Remember’) or familiarity (‘Know’), either reflecting episodic or semantic memory. Results. Patients showed a lack of ‘Remember responses’, which led to more opportunities to make ‘Know responses’. ERPs for ‘Remember’ compared to ‘New responses’ differed consistently in controls over left temporo-parietal and right frontal electrode sites. Although schizophrenic patients showed the same topography for this Remember old/new effect, it was apparent over temporo-parietal sites for only 800 ms and over right frontal sites for 1100 ms post-stimulus. For controls, the Know old/new effect was elicited over temporo-parietal sites between 500 and 800 ms. For patients, it showed a widespread maximum over frontal sites between 500 and 1100 ms. Conclusions. The shorter time course of the left temporo-parietal Remember old/new effect suggests that the patients' episodic memory impairment was possibly mediated by a dysfunction of the mediotemporal regions. The more widespread frontal Know old/new effect in the patients suggests that the prefrontly mediated processes associated with retrieval of semantic memory may be enhanced compensatorily.
Functional Outcome of Patients Following Open Reduction Internal Fixation for Bilateral Calcaneus Fractures

Treatment of displaced intra-articular calcaneus fractures has historically been controversial, but recent developments have led to resurgence in open reduction internal fixation (ORIF) for displaced calcaneus fractures. Recent functional outcome studies comparing operative to nonoperative treatment of unilateral calcaneus fractures has shown a trend towards improved function with ORIF. No studies have investigated the functional outcome of patients who have required operative treatment of bilateral displaced calcaneus fractures. The purpose of this study was to review our operative experience with bilateral displaced intra-articular calcaneal fractures. A retrospective review of medical charts indicated 13 patients had undergone ORIF for bilateral calcaneus fractures. Nine patients could be contacted and brought to the clinic for functional evaluation and radiographic CT studies. Functional outcome was assessed by the Musculoskeletal Functional Assessment Score (MFA) and the American Orthopaedic Foot and Ankle Hindfoot Score (AOFAS). The average follow-up was 56 months. Over half of the patients required additional surgeries. The average MFA and AOFAS scores were 31.1 and 71.8, respectively. Functional outcome decreased for patients with multiple traumatic fractures and surgical procedures of the calcaneus. Our results show a diminished functional outcome for patients sustaining bilateral calcaneus fractures treated with ORIF when compared to patients managed surgically for unilateral calcaneus fractures, but better functional outcomes than patients who do not undergo ORIF for unilateral calcaneus fractures. This diminished function limits work capacity and ability to perform daily activities that require standing.