Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of aortoiliac tortuosity on endovascular repair of abdominal aortic aneurysms: evaluation of 3D computer-based assessment.

OBJECTIVE The purpose of this study was to examine the effect of aortoiliac tortuosity, as assessed by observers and 3-dimensional (3D) computer-based methods, on the conduct and outcome of endovascular repair of abdominal aortic aneurysms. METHODS Infrarenal aortoiliac tortuosity was measured in 75 patients (mean follow-up, 14.8 +/- 10.4 months) who underwent endovascular repair of abdominal aortic aneurysms by using the following four methods: (1) grading by 2 experienced observers; (2) tortuosity index measured as the inverse radius of curvature (cm(-1)) at 1-mm intervals along the median luminal centerline (MLC) on 3D reconstructions of computed tomography (CT) angiograms and was calculated as the sum of values greater than 0.3 cm(-1); (3) MLC-straight line length ratio from renal to hypogastric arteries; (4) manual measurement of angles at points of angulation on anteroposterior and lateral projections of 3D CT reconstructions. In evaluating association between these measures, correlation between human observers was accepted as the gold standard. RESULTS For rating of overall aortoiliac tortuosity, interobserver correlation (r = 0.67) was comparable with correlation of observers with tortuosity index (r = 0.67 and 0.56), whereas correlations of each observer with MLC-straight line ratio (r = 0.50 and 0.56) and cumulative angulation (r = 0.44 and 0.44) were significant but weaker. For determining the relative tortuosity of right and left aortoiliac access, agreement between observers and tortuosity index (54% and 58%; P < .05; kappa, 0.33 and 0.38) was not as good as between observers (68%; P < .001; kappa, 0.53). This difference was primarily related to evaluation of the aorta, where interobserver correlation (r = 0.71) was better than that between each observer and tortuosity index (r = 0.47 and 0.55), whereas correlations in the iliac arteries were comparable (r = 0.64 and 0.67) (all coefficients P < .01). Increased tortuosity was associated with a more complex endovascular repair, as reflected by longer fluoroscopy time (P = .05), use of more contrast material (P = .03), use of extender modules (P = .04), and more frequent use of arterial reconstruction (P = .01), but was not associated with a higher overall complication rate. Increased tortuosity, when it occurred in the aortic neck, was associated with predischarge endoleak (P = .03) but not with late endoleak, intervention, or aneurysm-related adverse events. CONCLUSION Aortoiliac tortuosity is associated with increased complexity of endovascular aneurysm repair and with predischarge endoleak but does not appear to affect intermediate-term results. Computer-based 3D measurement of aortoiliac tortuosity is feasible and clinically meaningful. Its ultimate role in relation to human assessment must be further defined in future studies.
Histone H2B Monoubiquitination in the Chromatin of FLOWERING LOCUS C Regulates Flowering Time in Arabidopsis[W]

Ubiquitination is one of many known histone modifications that regulate gene expression. Here, we examine the Arabidopsis thaliana homologs of the yeast E2 and E3 enzymes responsible for H2B monoubiquitination (H2Bub1). Arabidopsis has two E3 homologs (HISTONE MONOUBIQUITINATION1 [HUB1] and HUB2) and three E2 homologs (UBIQUITIN CARRIER PROTEIN [UBC1] to UBC3). hub1 and hub2 mutants show the loss of H2Bub1 and early flowering. By contrast, single ubc1, ubc2, or ubc3 mutants show no flowering defect; only ubc1 ubc2 double mutants, and not double mutants with ubc3, show early flowering and H2Bub1 defects. This suggests that ubc1 and ubc2 are redundant, but ubc3 is not involved in flowering time regulation. Protein interaction analysis showed that HUB1 and HUB2 interact with each other and with UBC1 and UBC2, as well as self-associating. The expression of FLOWERING LOCUS C (FLC) and its homologs was repressed in hub1, hub2, and ubc1 ubc2 mutant plants. Association of H2Bub1 with the chromatin of FLC clade genes depended on UBC1,2 and HUB1,2, as did the dynamics of methylated histones H3K4me3 and H3K36me2. The monoubiquitination of H2B via UBC1,2 and HUB1,2 represents a novel form of histone modification that is involved in flowering time regulation.
Quality Estimation Of Machine Translation Outputs Through Stemming

Machine Translation is the challenging problem for Indian languages. Every day we can see some machine translators being developed, but getting a high quality automatic translation is still a very distant dream . The correct translated sentence for Hindi language is rarely found. In this paper, we are emphasizing on English-Hindi language pair, so in order to preserve the correct MT output we present a ranking system, which employs some machine learning techniques and morphological features. In ranking no human intervention is required. We have also validated our results by comparing it with human ranking.
High speed automated pulsed I/V measurement system

Thermal and trap effects in GaAs MESFET and HEMT devices can be accurately studied using Pulsed Gate and Drain measurement systems. Modelling methods based on static, pulsed I/V characteristics along with S parameters can be implemented into nonlinear simulators in order to obtain better agreement with the experiment. This work proposes a new compact instrumentation philosophy for Pulsed I/V measurements (PIVMS) that achieves 16bit resolution in 300ns pulse widths, avoiding the need for complex expensive external instrumentation and/or Hall effect current probes. The measurement system has been designed to meet requirements of high speed automated test systems, tacking about 20sec for extracting a complete set of bias points. Experimental verification shows the performance of this instrumentation setup.
Close association of HLA-B52 and HLA-B44 antigens in Israeli Arab adolescents with recurrent aphthous stomatitis.

OBJECTIVES To investigate the incidence and clinical features of recurrent aphthous stomatitis (RAS) among Israeli Arab adolescents and to determine the HLA typing profile in affected subjects. STUDY DESIGN Cross-sectional study. SETTING Junior high school in the largest Arab town in Israel. PARTICIPANTS Four hundred seventy-seven Israeli Arab junior high school students filled out a questionnaire. Students who reported more than 4 episodes of RAS during the previous year were interviewed by telephone. Those whose responses were confirmed were invited to the clinic. Of these, 22 were chosen at random for HLA typing. Findings were compared with those in 117 healthy Israeli Arabs who were candidate donors of bone marrow to patients at the Institute of Hematology-Oncology, Schneider Children's Medical Center of Israel, Petah Tiqva. RESULTS Recurrent aphthous stomatitis was confirmed in 80 subjects (16.7%). Of the 22 patients who underwent HLA typing, 7 (31.4%) had HLA-B52 antigens and 8 (36.4%) had HLA-B44 antigens; corresponding figures for the control group were 10 subjects (8.5%) (P = .007) and 9 subjects (7.7%) (P = .001), respectively. CONCLUSIONS There is a close association of HLA-B52 and HLA-B44 in Israeli Arab youths with RAS. Long-term follow-up is needed to determine the relationship between RAS and Behçet disease.
Intravenous lipid emulsion and dexmedetomidine for treatment of feline permethrin intoxication: a report from 4 cases

Four cases of feline permethrin intoxication are described. The cause of intoxication is the application of canine permethrin spot-on product (Advantix®, Bayer) by the owners. Principal clinical guidelines recommends the use of anticonvulsant drugs to treat seizures or neurological symptoms after initial stabilization and dermal decontamination. The use of lipid emulsion had an increasing interest in the last decade for treatment of toxicosis caused by lipophylic drugs as reported in human and in veterinary medical practices. All cats presented in this study, were treated with intravenous lipid emulsion (ILE) at variable dosages, and dexmedetomidine was also administered by intravenous way. No adverse reaction such as thrombophlebitis, overload circulation or others was noticed during and after administration of ILE. Dexmedetomidine was proved to be helpful in tranquillizing the cats. All cats were discharged in good condition faster than other cases treated without their use.
A structural and functional ground plan for neurons in the hindbrain of zebrafish

The vertebrate hindbrain contains various sensory-motor networks controlling movements of the eyes, jaw, head, and body. Here we show that stripes of neurons with shared neurotransmitter phenotype that extend throughout the hindbrain of young zebrafish reflect a broad underlying structural and functional patterning. The neurotransmitter stripes contain cell types with shared gross morphologies and transcription factor markers. Neurons within a stripe are stacked systematically by extent and location of axonal projections, input resistance, and age, and are recruited along the axis of the stripe during behavior. The implication of this pattern is that the many networks in hindbrain are constructed from a series of neuronal components organized into stripes that are ordered from top to bottom according to a neuron's age, structural and functional properties, and behavioral roles. This simple organization probably forms a foundation for the construction of the networks underlying the many behaviors produced by the hindbrain.
Neuropeptide Y in mammalian genital tract: localization and biological action.

Neuropeptide Y, NPY, is one of the most common neuropeptides in mammalian and seems to influence many physiological systems significantly, e.g. the cardiovascular system and the gastrointestinal system. In the present investigation the distribution, localization and physiological effects of NPY were studied in the mammalian genital tract, primarily the female. In the human female genital tract the highest concentrations of NPY-immunoreactivity, NPY-IR, measured by radioimmunoassay, were demonstrated in the uterine artery, the ovary, the Fallopian tube, and the vagina. Immunohistochemical investigations demonstrated the highest density of NPY immunoreactive nerve fibers in relation to blood vessels, although some NPY-IR nerves also were seen close to non-vascular smooth muscle. In the ovary, many NPY-IR nerves were observed in connection with follicles. The NPY-IR material throughout the genital tract was identical to synthetic, amidated human NPY as evaluated by gel filtration, high performance liquid chromatography, and isoelectric focusing. Pro-NPY and NPY-IR material was also demonstrated in human plasma and follicular fluid. NPY induced only a weak direct contractile effect on small cervical arteries from humans investigated in vitro by isometric tension measurements. NPY had no effect on smooth muscle specimens either from the salpinx or the uterus. The 133Xe washout method was evaluated on the rabbit ovary in order to measure changes in the ovary blood flow rate in vivo. A mono-exponential washout curve for 133Xe was found for the whole washout process, ensuring that the blood flow rate at any time could be calculated from the curve. Injection of NPY close to ovarian artery resulted in a dose dependent decrease in the ovarian blood flow rate with a maximum reduction to 40% of the control blood flow rate. In vitro investigation of the rabbit ovarian artery demonstrated only a weak direct contractile effect of NPY but a significant potentiation of the NA response was observed. In vessels precontracted with NA, it was demonstrated that NPY was a potent inhibitor of vasoactive intestinal peptide-induced relaxation. The postsynaptic contractile NPY effects in the rabbit ovarian artery were most likely mediated through a NPY Y1 receptor as demonstrated by the effect of the selective NPY Y1 receptor agonist [Leu31,Pro34]NPY and the Y2 receptor agonist, NPY11-36. The presynaptic inhibitory effect of NPY on the vas deferens motor response induced by electrical stimulation was possibly caused by stimulation of NPY Y2 receptors as evaluated by the effect of the above mentioned peptide analogs in this system. (ABSTRACT TRUNCATED AT 400 WORDS)
Cell-Based Therapies for Lumbar Discogenic Low Back Pain: Systematic Review and Single-Arm Meta-analysis

Study Design. A systematic review and single-arm meta-analysis of clinical trials. Objective. To assess the efficacy of mesenchymal stem cells or chondrocyte in patients with discogenic low back pain. Summary of Background Data. There is no previous review evaluated the efficacy of mesenchymal stem cell or chondrocyte therapy in adults with discogenic low back pain. Methods. A comprehensive literature search was conducted on PubMed, Ovid MEDLINE, Ovid EMBASE, EBSCO, and Web of Science from database inception through on September 10th, 2015. We included clinical trials that evaluated stem cells or chondrocyte-based therapy in patients with discogenic back pain. The primary outcomes of interest were pain score and Oswestry Disability Index (ODI). We performed random-effects model meta-analyses to assess net changes in the same outcome variables. Heterogeneity between studies was estimated by I 2 statistic. Results. The initial search identified 1393 articles, of which 6 studies were eligible for this review. The pooled mean difference in pain score from baseline to follow-up points was 44.2 points decreased (95% CI: −61.8 to −26.5, P < 0.001, I 2 = 99.4%). Meanwhile, the pooled mean difference in ODI from baseline to follow-up points was 32.2 points decreased (95% CI: −41.6 to −22.9, P < 0.001, I 2 = 99.5%). No related adverse effects were reported by the included studies. Conclusion. Cell-based therapy is for patients who have discogenic low back pain associated with improved pain relief and ODI. More stringently designed randomized double-blind clinical trials with appropriately determined sample sizes will be needed to confirm its clinical efficacy and safety. Level of Evidence: 4
Microstructure-Sensitive Models for Predicting Surface Residual Stress Redistribution in P/M Nickel-Base Superalloys

iv ACKNOWLEDGEMENTS . vi LIST OF ILLUSTRATIONS. xi LIST OF TABLES . xx LIST OF SYMBOLS . xxi CHAPTER I: INTRODUCTION . 1 Problem Description . 2 Objective . 3 Significance of Research . 3 Overview . 4 CHAPTER II: BACKGROUND AND LITERATURE REVIEW. 6 IN100 Material . 6 Influence of Microstructure on Mechanical Properties . 8 Residual Stress and Mechanical Surface Treatments . 10 Shot Peening and Microstructure . 15 CHAPTER III: MICROSTRUCTURAL CHARACTERIZATION . 17 Grain Size Measurement . 17 Precipitate Size and Distribution . 22 CHAPTER IV: MATERIAL BEHAVIOR EXPERIMENTS AND MODEL DEVELOPMENT . 26 Experimental Overview . 27
Reporting Structural Equation Modeling and Confirmatory Factor Analysis Results: A Review

ABSTRACT The authors provide a basic set of guidelines and recommendations for information that should be included in any manuscript that has confirmatory factor analysis or structural equation modeling as the primary statistical analysis technique. The authors provide an introduction to both techniques, along with sample analyses, recommendations for reporting, evaluation of articles in The Journal of Educational Research using these techniques, and concluding remarks.
NEW X-RAY OBSERVATIONS OF THE OLD NOVA CP PUPPIS AND OF THE MORE RECENT NOVA V351 PUPPIS

We present X-ray observations of the field containing Nova Puppis 1942 (CP Pup) and Nova Puppis 1991 (V351 Pup), done with ASCA in 1998, and with XMM-Newton in 2005. The X-ray and UV luminosity of CP Pup seem to have remained approximately constant since the last X-ray observations of the 1980s, while the optical luminosity has decreased. The X-ray properties of this nova are explained by a high-mass white dwarf (WD) accreting at low rate, in agreement with the nova theory given the large amplitude and other characteristics of the 1942 outburst. Assuming a distance of 1600 pc, the X-ray luminosity of CP Pup is Lx = 2.2 × 1033 erg s−1 in the 0.15–10 keV range covered with EPIC, compatible with a magnetic system. The RGS grating spectrum shows a few prominent emission lines, and it is fitted with a cooling flow with mass accretion rate <1.6 × 10−10 M☉ yr−1. We also detected the O vii complex at 21.6–21.8 Å that does not arise in the cooling flow. Most likely this feature originates in a wind or in the nova shell. The RGS and EPIC spectra are fitted only with thermal models with a very high shock temperature, T > 60 keV, indicating a WD with M > 1.1 M☉. The X-ray flux is modulated with the spectroscopic period of 1.47 hr detected in the optical. Since CP Pup is not an eclipsing system, this is better understood if magnetic accretion occurs: we discuss this possibility and its implications in detail. V351 Pup was detected with XMM-Newton, but not with ASCA. It is a faint, nonsupersoft X-ray source with luminosity Lx ≃ 3 × 1031 erg s−1, a factor of 50 less than measured with ROSAT in 1993.
Impact of printed wiring board coatings on the reliability of lead-free chip-scale package interconnections

When lead-free solder alloys mix with lead-free component and board metallizations during reflow soldering, the solder interconnections become multicomponent alloy systems whose microstructures cannot be predicted on the basis of the SnPb metallurgy. To better understand the influences of these microstructures on the reliability of lead-free electronics assemblies, SnAgCu-bumped components were reflow-soldered with near-eutectic SnAgCu solder pastes on Ni(P)|Au- and organic solderability preservative (OSP)-coated printed wiring boards and tested under cyclic thermal shock loading conditions. The reliability performance under thermomechanical loading was found to be controlled by the kinetics of recrystallization. Because ductile fracturing of the as-soldered tin-rich colonies would require a great amount of plastic work, the formation of continuous network of grain boundaries by recrystallization is needed for cracks to nucleate and propagate intergranularly through the solder interconnections. Detailed microstructural observations revealed that cracks nucleate and grow along the grain boundaries especially between the recrystallized part and the non-recrystallized part of the interconnections. The thermal cycling test data were analyzed statistically by combining the Weibull statistics and the analysis of variance. The interconnections on Ni(P)|Au were found out to be more reliable than those on Cu|OSP. This is due to the extensive dissolution of Cu conductor, in the case of the Cu|OSP assemblies, into molten solder that makes the microstructure to differ noticeably from that of the Ni(P)|Au interconnections. Because of large primary Cu6Sn5 particles, the Cu-enriched interconnections enhance the onset of recrystallization, and cracking of the interconnections is therefore faster. The solder paste composition had no statistically significant effect on the reliability performance.
Integrated link adaptation and power control to improve error and throughput performance in broadband wireless packet networks

In this paper, we prove that the problem of maximizing data throughput by adaptive modulation and power control while meeting packet error requirements is NP-complete. A heuristic algorithm for integrated link adaptation and power control is, thus, proposed to achieve specified error rates and to improve overall throughput for real-time applications in broadband wireless packet networks. The algorithm divides terminals into groups according to their signal path gains and periodically adapts transmissions based on the required error rates, actual error statistics, and average transmission power of each terminal group. Transmission power is adjusted by an enhanced Kalman-filter method to ensure successful reception. Extensive simulation results reveal that the algorithm consistently delivers the specified error performance and attempts to maximize network throughput for a wide range of parameter settings.
Gevrey Order of Formal Power Series Solutions of Inhomogeneous Partial Differential Equations with Constant Coefficients

In an earlier paper, the first author showed that certain normalized formal solutions of homogeneous linear partial differential equations with constant coefficients are multisummable, with a multisummability type that can be determined from a Newton polygon associated with the PDE. In this article, some of the results obtained there are extended in several directions: First of all, arbitrary formal solutions of inhomogeous PDE are considered, and it is shown that, in some sense, they can be computed completely explicitly. Secondly, the Gevrey order of these formal solutions is determined. Finally, formal power series are discussed that, in general, do not satisfy a PDE with constant coefficients, but instead may be considered as solutions of singularly perturbed ODE, or integro-differential equations of a certain form. Introduction In [3, 6], the first author introduced and studied normalized formal solutions of a Cauchy problem for general homogeneous linear partial differential equations in two variables having constant coefficients. Multisummability of these formal power series was then investigated in [4]. In detail, it has been shown that, under the assumption that the initial condition used is holomorphic near the origin, one can determine a multisummability type corresponding naturally to the PDE under consideration. The normalized formal solution then is multisummable in a given multidirection, provided that the initial condition can be continued into finitely many (small) sectors, and in every such sector is at most of a certain exponential growth that, in general, depends upon the sector. The multisummability type, the location of the sectors, and the corresponding ∗Institut fur Angewandte Analysis, Universitat Ulm, D–89069 Ulm, Germany †Department of Mathematics, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526 Japan
Short-term safety and efficacy of intravitreal triamcinolone acetonide for uveitic macular edema in children.

OBJECTIVES To evaluate the short-term safety and efficacy of intravitreal (IV) triamcinolone acetonide (TA) for treating pediatric cystoid macular edema (CME) secondary to noninfectious uveitis. METHODS A retrospective noncomparative interventional case series. The medical records of 15 consecutive children (16 eyes) with uveitic CME treated with IVTA (2 or 4 mg) were reviewed. Data collected included details of uveitis, CME, visual acuity, intraocular pressure, and cataract development. The median follow-up time was 16 months (range, 9-36 months). RESULTS Resolution of CME was achieved in all of the treated eyes. The median time taken for CME to resolve was 3 weeks (range, 1-24 weeks). The mean improvement of visual acuity after IVTA was 0.6 logarithm of the minimum angle of resolution. Following initial response to IVTA, CME relapsed in 5 eyes (31%) after a median time of 7 months (range, 3-13 months). The most common adverse effect was increased intraocular pressure, with an increase of more than 15 mm Hg in 5 eyes (31%). Steroid-induced cataract was observed in 6 of 11 phakic eyes (55%). CONCLUSIONS We found that IVTA is efficacious in the treatment of uveitic CME in children and results in CME resolution and visual acuity improvement. As in adults, treatment in children may be associated with elevated intraocular pressure and cataract.