Miracle-dz/UniFAR-FTUs huggingface dataset:
Study of the Paired Change Points in Bacterial Genes

It is known that nucleotide sequences are not totally homogeneous and this heterogeneity could not be due to random fluctuations only. Such heterogeneity poses a problem of making sequence segmentation into a set of homogeneous parts divided by the points called “change points”. In this work we investigated a special case of change points-paired change points (PCP). We used a well-known property of coding sequences-triplet periodicity (TP). The sequences that we are especially interested in consist of three successive parts: the first and the last parts have similar TP while the middle part has different TP type. We aimed to find the genes with PCP and provide explanation for this phenomenon. We developed a mathematical method for the PCP detection based on the new measure of similarity between TP matrices. We investigated 66,936 bacterial genes from 17 bacterial genomes and revealed 2,700 genes with PCP and 6,459 genes with single change point (SCP). We developed a mathematical approach to visualize the PCP cases. We suppose that PCP could be associated with double fusion or insertion events. The results of investigating the sequences with artificial insertions/fusions and distribution of TP inside the genome support the idea that the real number of genes formed by insertion/ fusion events could be 5-7 times greater than the number of genes revealed in the present work.
Luxury Suites and Team Selling in Professional Sport

Purpose – The purpose of this paper is to provide a framework for team selling to sports firms that can be used to more effectively select members for sales and CRM teams and improve the performance of teams in attracting and retaining premium seating customers.Design/methodology/approach – The paper provides a two‐stage framework based on the personal selling process and the activities that support CRM programs. Recommendations are guided by the sport marketing and team selling literature streams and by best practices in sport marketing.Findings – The paper recommends the formation of two teams (personal selling and CRM) during the customer relationship cycle and provides guidelines for team member selection based on the critical activities that occur during the personal selling and CRM processes. Key success factors are provided, including the establishment of a customer‐focused organization and effective communication practices among team members and between selling teams.Originality/value – Although t.
Instruction Sequence Size Complexity of Parity

Each Boolean function can be computed by a single-pass instruction sequence that contains only instructions to set and get the content of Boolean registers, forward jump instructions, and a termination instruction. Auxiliary Boolean registers are not necessary for this. In the current paper, we show that, in the case of the parity functions, shorter instruction sequences are possible with the use of an auxiliary Boolean register in the presence of instructions to complement the content of auxiliary Boolean registers. This result supports, in a setting where programs are instruction sequences acting on Boolean registers, a basic intuition behind the storage of auxiliary data, namely the intuition that this makes possible a reduction of the size of a program.
Inhibited Arousal in Women

Female sexual arousal disorder (FSAD) is a common condition in women that frequently copresents with hypoactive sexual desire disorder (HSDD). Although some of the principles and practice within clinical management of these 2 conditions is similar, it is essential that as accurate a diagnosis and assessment as possible is made to clarify the thinking and formulation of the problem(s) for the clinician, woman, or her partner. The clinician needs to have a wide range of tools and knowledge in order to integrate the physical, relational, and psychological interventions that are needed for the individual to understand the diagnosis and what options are available. Various assessments and treatment options are presented along with a case example.
Development and Assessment of Executive Function in Children

There is increasing evidence that the development of the frontal lobes is a prolonged multi stage process continuing into adolescence. Research has indicated that damage to the frontal lobes may be detected from infancy. Downward extensions of tests from adult neuropsychology are not always suitable for use with infants and young children. There is a need to use tests in the routine neuropsychological assessment of children that have originated in cognitive developmental research. Executive and frontal functions are implicated in learning disabilities and several psychiatric disorders and therefore should be tested more frequently in clinical assessment.
Diagnostic interviewing for family studies: Comparing telephone and face-to-face methods for the diagnosis of lifetime psychiatric disorders

Family studies require assessment of large numbers of family members, many of whom are geographically dispersed, live in different time zones, are not available during working hours, live in neighborhoods which are unsafe, or do not wish to have attention drawn to them by the presence of an interviewer in their home. For these reasons, telephone interviews are a potentially valuable and economical method. We present a comparison of results from telephone and face-to-face interviews conducted with 435 relatives of 193 probands from a family study. No significant differences were found between telephone versus face-to-face interviewed relatives in rates of RDC or of DSM-III-R diagnoses. Nor were differences found in the length of interviews; number of family history reports completed; or number of relatives requiring consensus diagnoses due to diagnostic disagreement. We conclude that telephone and face-to-face interviews yielded comparable diagnostic information in this family study and that telephone interviewing is an acceptable and valuable alternative method for the diagnosis of lifetime psychiatric disorder in relatives.
Affine Term Structure Models and the Forward Premium Anomaly

One of the most puzzling features of currency prices is the forward premium anomaly: the tendency for high interest rate currencies to appreciate. We characterize the anomaly in the context of affine models of the term structure of interest rates. In affine models, the anomaly requires either that state variables have asymmetric effects on state prices in different currencies or that nominal interest rates take on negative values with positive probability. We find the quantitative properties of either alternative to have important shortcomings. PERHAPS THE MOST PUZZLING FEATURE of currency prices is the tendency for high interest rate currencies to appreciate when one might guess, instead, that investors would demand higher interest rates on currencies expected to fall in value. This departure from uncovered interest parity, which we term the forward premium anomaly, has been documented in dozens—and possibly hundreds—of studies, and has spawned a second generation of papers attempting to account for it. One of the most inf luential of these is Fama ~1984! , who attributes the behavior of forward and spot exchange rates to a time-varying risk premium. Fama shows that the implied risk premium on a currency must ~1! be negatively correlated with its expected rate of depreciation and ~2! have greater variance. We refer to this feature of the data as an anomaly because asset pricing theory to date has been notably unsuccessful in producing a risk premium with the requisite properties. Attempts include applications of the capital asset pricing model to currency prices ~Frankel and Engel ~1984! , Mark ~1988! , statistical models relating risk premiums to changing second moments ~Hansen and Hodrick ~1983! , Domowitz and Hakkio ~1985! , Cumby ~1988! , and consumption-based asset pricing theories, including departures from time
Track and Connect: Enhancing student retention and success at the University of Sydney. A Practice Report

In 2012, staff in Student Support Services at The University of Sydney piloted an early intervention program to increase first year student engagement and retention. Founded in best-practice, evidence-based research, the Track and Connect program was developed in response to a study into first year undergraduate student attrition by the University’s Planning and Information Office, in consultation with Counselling and Psychological Services. Track and Connect provides tailored advice and support to students identified as at risk of withdrawal from a key first-year subject by demographic markers and on-time data. Trained senior peers contact these students and provide information, encouragement and service referrals at key decision points throughout the semester. This report outlines the program’s development, implementation and early outcomes, and identifies areas for refinement and expansion.
The dangers of essentialism: South Asian communities in Britain and the ‘world religions’ approach to the study of religions

Astract This article is the result of extensive fieldwork undertaken among various South Asian religious communities that originated primarily from East and West Punjab and are now established in a number of British cities, but are concentrated in the West Midlands and London. While the field studies were carried out as part of a wider exploration of Muslim, Sikh and Hindu communities in the British South Asian Diaspora, it was not long before the author realised that the diversity of belief and practice within each community and the degree of eclectic blurring of the usual categorisation of religions called into question the labelling of discrete traditions used in the ‘world religions’ paradigm. The article argues not only that is there a risk of academic distortion creating constructions of religions that do not conform to the etic reality, but also that the reliance of educators at all levels on an essentialised view of South Asian religious ideas and practices presents itself as a danger in terms of the implicit reinforcement of established power structures.
The p66shc Gene Expression in Peripheral Blood Monocytes Is Increased in Patients With Coronary Artery Disease

The p66shc protein has been shown to control cellular responses to oxidative stress, being involved in atherosclerosis in animal models. However, the relationship between the p66shc gene expression levels and coronary artery disease (CAD) in humans remains unknown. In this study, we examined whether the p66shc gene expression in peripheral blood monocytes (PBMs) was increased in patients with CAD, compared with age‐ and sex‐matched subjects without CAD.
Children's expressive language in early toddlerhood: links to prior maternal mind-mindedness

This study examines the prospective links between early maternal mind-mindedness, including references to different types of mental states, and child subsequent expressive vocabulary. Eighty-four mother–infant dyads took part in two assessments. At one year of age, maternal mind-mindedness was assessed during mother–child free play in the home, and at two years, mothers completed the MacArthur Communicative Development Inventory to evaluate children's expressive vocabulary. Maternal mind-mindedness was related to children's expressive language, above and beyond family socio-economic status. Specifically, only maternal comments on child cognitions were related to children's expressive language. The findings suggest that maternal mind-mindedness is relevant to understanding children's language development while highlighting the importance of considering the exact nature of mind-related comments.
Interpretation of standards with Bloom’s revised taxonomy: a comparison of teachers and assessment experts

In education, standards have to be interpreted, for planning of teaching, for development of assessments and for alignment analysis. In most cases, it is important that there is an agreement between individuals and organizations about how to interpret standards. However, there is a lack of studies of how consistent different group of judges are when interpreting standards. In this study, the usefulness of Bloom’s revised taxonomy for interpreting standards in mathematics is evaluated, using different criteria. The results indicate that the taxonomy is an acceptable tool. The results also indicate that there are differences between the panel composed of teachers and the panel composed of assessment experts. The assessment experts were more consistent in their interpretation of standards. Limitations of the study and requirements for alignment analysis are discussed.
An ecological Theory of Motion Sickness and Postural Instability

In this article we present a new theory of motion sickness. In the sensory conflict theory, changes in stimulation of perceptual systems are believed to be responsible for motion sickness. We discuss the fact that these changes in stimulation are not independent of the animal-environment interaction, but are determined by corresponding changes in the constraints operating on the control of action. Thus, provocative situations may be characterized by novel demands on the control of action as well as by novel patterns of stimulation. Our hypothesis is that animals become sick in situations in which they do not possess (or have not yet learned) strategies that are effective for the maintenance of postural stability. We identify a broad range of situations over which the occurrence of motion sickness is related to factors that should influence postural stability. This allows us to establish a logical link between motion sickness and postural stability. Our analysis implies that an understanding of stability s.
Regional integration and economic development: An empirical approach

This paper contributes to the empirical literature by providing a quantitative measurement of the influence of regional trade integration on productivity. For this purpose we address the link between trade and productivity thanks to knowledge spillovers in a multi-country model. The interdependence that connects countries in an international web promotes exchanges of goods, services, people, capital and hence ideas, knowledge, innovation, and technology. Economic integration encourages thus both new ideas and their diffusion. We observe that a countryâ€™s productivity depends on its own R&D efforts as well as the R&D efforts of its trading partners. These R&D spillovers can then spread across countries and sectors. Thanks to the transfer of technology allowed by bilateral trade and investment, regional trade integration has a positive impact on long-term growth.
Swinging All the Way: The Education of Doctor Lucas and Foes

��� The canons of orthodoxy selected a peculiar vision of social evolution: the focus of economics on the analysis of the emergence and dominance of markets, described as the institutions constructed by the rule of individual maximization. In that framework, the originally established definition of equilibrium—the intrinsic drive to the changeless state of stasis—was certainly a paradoxical requisite for success. Yet, the concept of equilibrium became a cornerstone of modern economic theory, namely for very practical and concrete reasons: it provided the justification and the rationale for exhaustive quantification and computation, identified as legitimate knowledge responding to the positivist criterion of enlightening science. In that sense, orthodoxy imposed a contradictory scientific program, since change and disequilibrium, and not conservation and equilibrium, are the very nature of social relations. Nothing revealed the contradiction better than the inquiry into fluctuations of economic life. Leon Walras intuitively argued for such a static concept of equilibrium, with his powerful metaphor of the lake: the market permanently tends to stasis, which is permanently disturbed just as the level of the lake is disturbed by the wind, “the level of the water always looking
Investigating text normalization and pronunciation variants for German broadcast transcription

In this paper we describe our ongoing work concerning lexical modeling in the LIMSI broadcast transcription system for German. Lexical decomposition is investigated with a twofold goal: lexical coverage optimization and improved letter-t o-sound conversion. A set of about 450 decompounding rules, developed using statistics from a 300M word corpus, reduces the OOV rate from 4.5% to 4.0% on a 30k development text set. Adding partial inflection stripping, the OOV rate drops to 2.9%. For let terto-sound conversion, decompounding reduces cross-lexeme ambiguities and thus contributes to more consistent pronunci ation dictionaries. Another point of interest concerns reduced p ronunciation modeling. Word error rates, measured on 1.3 hours of ARTE TV broadcast, vary between 18 and 24% depending on the show and the system configuration. Our experiments indicate that using reduced pronunciations slightly decreases word erro r rates.
CONTRADICTORY COUPLINGS: PROFESSIONAL IDEOLOGY IN THE ORGANIZATIONAL LOCALES OF NURSE TRAINING

Nursing is a contemporary occupation which has developed an explicit ‘professional project’. In the UK this has centred around an occupational ideology which stresses managerialism and credentialism. This occupational ideology comes into contradiction with older conceptions of professionalism which are couched in vocational terms. The vocational meaning is shown to be situated and reproduced in organizational locales which serve to undercut the managerialist and credentialist meanings. The focus of these cross-cutting meanings is the interpretation of a ‘good nurse’. Using a ‘negotiated order’ perspective, focusing on ‘contradictions’, case study material suggests that there are important gaps between formal representations of the professionalism project and the actual, situated practice of ‘nursing’. For trainee nurses these gaps are particularly apparent. In day-to-day organizational life they have to negotiate contradictory conceptions encountered in the diverse locales of ward work and nurse training. In addition, the different meanings may be encountered even in the same locales.
The Human DnaJ Homologue dj2 Facilitates Mitochondrial Protein Import and Luciferase Refolding

DnaJ homologues function in cooperation with hsp70 family members in various cellular processes including intracellular protein trafficking and folding. Three human DnaJ homologues present in the cytosol have been identified: dj1 (hsp40/hdj-1), dj2 (HSDJ/hdj-2), and neuronal tissue-specific hsj1. dj1 is thought to be engaged in folding of nascent polypeptides, whereas functions of the other DnaJ homologues remain to be elucidated. To investigate roles of dj2 and dj1, we developed a system of chaperone depletion from and readdition to rabbit reticulocyte lysates. Using this system, we found that heat shock cognate 70 protein (hsc70) and dj2, but not dj1, are involved in mitochondrial import of preornithine transcarbamylase. Bacterial DnaJ could replace mammalian dj2 in mitochondrial protein import. We also tested the effects of these DnaJ homologues on folding of guanidine-denatured firefly luciferase. Unexpectedly, dj2, but not dj1, together with hsc70 refolded the protein efficiently. We propose that dj2 is the functional partner DnaJ homologue of hsc70 in the mammalian cytosol. Bacterial DnaJ protein could replace mammalian dj2 in the refolding of luciferase. Thus, the cytosolic chaperone system for mitochondrial protein import and for protein folding is highly conserved, involving DnaK and DnaJ in bacteria, Ssa1–4p and Ydj1p in yeast, and hsc70 and dj2 in mammals.
The Safe Schools/Healthy Students (SS/HS) initiative: Lessons learned from implementing comprehensive youth development programs

The goal of this joint initiative of the U.S. Departments of Education (DOE), Health and Human Services (HHS), and Justice (DOJ) is to provide students, schools, and communities with enhanced comprehensive educational, mental health, social service, law enforcement, and juvenile justice system services that promote healthy childhood development and prevent violence and alcohol and drug abuse. (Office of Juvenile Justice and Delinquency Prevention, 1999)
Implant Bed Preparation with an Erbium, Chromium Doped Yttrium Scandium Gallium Garnet (Er,Cr: YSGG) Laser Using Stereolithographic Surgical Guide.

BACKGROUND Implant bed preparation with laser is taken into consideration owing to the increased interest in use of lasers in hard tissue surgery. The purpose of this study is to determine the deviations in the position and inclination between the planned and prepared implant beds with Erbium, Chromium doped Yttrium Scandium Gallium Garnet (Er,Cr:YSGG) laser using stereolithographic (SLA) surgical guides. METHODS After 3-dimensional (3D) imaging of six sheep lower jaws, computed tomography (CT) images were transformed into 3D models. Locations of implant beds were determined on these models. Two implant beds in each half jaw were prepared with an Er,Cr:YSGG laser system and a conventional drilling method using a total of 12 SLA surgical guides. A new CT was taken to analyze the deviation values between planned and prepared implant beds. Finally, a software program was used to superimpose the images on 3D models, then the laser and conventional drilling groups were compared. RESULTS Differences of mean angular deviations between the planned and prepared implant beds were 5.17±4.91° in the laser group and 2.02±1.94° in the conventional drilling group.The mean coronal deviation values were found to be 0.48±0.25 mm and 0.23±0.14 mm in the laser group and conventional drilling group, respectively. While the mean deviation at the apex between the planned and prepared implant beds were 0.70±0.26 mm and 0.26±0.08 ,the mean vertical deviations were 0.06±0.15 mm and 0.02±0.05 mm for the laser group and the conventional drilling group, respectively. CONCLUSION It is possible to prepare an implant bed properly with the aid of Er,Cr:YSGGlaser by using SLA surgical guide.