Miracle-dz/UniFAR-FTUs huggingface dataset:
On uncertainty measures used for decision tree induction

This paper provides a further look at uncertainty or information criteria used in the context of decision tree induction, and more generally of learning conditional class probability models. We show the high degree of similarity among two main families of criteria based respectively on the logarithmic SHANNON entropy function and the quadratic GINI index. We start by introducing a general family of entropy functions and then discuss the latter particular cases, and end up with a short review of the Kolmogorov-Smirnov distance, another related measure. 1 Generalized Information Functions The concept of generalized information functions of type β was first introduced by Daroczy [1] and its use for pattern recognition problems was discussed by Devijver [2]. The entropy of type β (β positive and different from 1) of a discrete probability distribution (p1, . . . , pm) is defined by H(p1, . . . , pm) △ = m
Simulation of surface potential decay of corona char ged polyimide

Surface potential decay (SPD) of corona charged polyimide (PI) films has been studied using different initial potentials Vo. It has been noticed that the rate of decay increases with initial charging levels. Surface potential profile over the surface of the PI films and return potential generated after charge neutralization have been also experimentally recorded. In order to analyse and explain the decay behavior, the recorded SPD in PI film has been computer simulated using a numerical model based on charge transport by hopping of injected carriers between localized trapping centers. Three parameters (transit time tT, trapping time τT and mean capture time before release τF) controlling the decay kinetic have been estimated by fitting procedure. The effects of the electric field strength on the transport parameters have been also discussed.
The Energy Landscape for Ubihydroquinone Oxidation at the Qo Site of the bc 1 Complex inRhodobacter sphaeroides *

Activation energies for partial reactions involved in oxidation of quinol by the bc 1complex were independent of pH in the range 5.5–8.9. Formation of enzyme-substrate complex required two substrates, ubihydroquinone binding from the lipid phase and the extrinsic domain of the iron-sulfur protein. The activation energy for ubihydroquinone oxidation was independent of the concentration of either substrate, showing that the activated step was in a reaction after formation of the enzyme-substrate complex. At all pH values, the partial reaction with the limiting rate and the highest activation energy was oxidation of bound ubihydroquinone. The pH dependence of the rate of ubihydroquinone oxidation reflected the pK on the oxidized iron-sulfur protein and requirement for the deprotonated form in formation of the enzyme-substrate complex. We discuss different mechanisms to explain the properties of the bifurcated reaction, and we preclude models in which the high activation barrier is in the second electron transfer or is caused by deprotonation of QH2. Separation to products after the first electron transfer and movement of semiquinone formed in the Qo site would allow rapid electron transfer to heme b L. This would also insulate the semiquinone from oxidation by the iron-sulfur protein, explaining the efficiency of bifurcation.
Design and Deployment of Sensor Network for Real-Time High-Fidelity Volcano Monitoring

This paper presents the design and deployment experience of an air-dropped wireless sensor network for volcano hazard monitoring. The deployment of five self-contained stations into the rugged crater of Mount St. Helens only took one hour with a helicopter. The stations communicate with each other through an amplified 802.15. 4 radio and establish a self-forming and self-healing multihop wireless network. The transmit distance between stations was up to 8 km with favorable topography. Each sensor station collects and delivers real-time continuous seismic, infrasonic, lightning, GPS raw data to a gateway. The main contribution of this paper is the design of a robust sensor network optimized for rapid deployment during periods of volcanic unrest and provide real-time long-term volcano monitoring. The system supports UTC-time-synchronized data acquisition with 1 ms accuracy, and is remotely configurable. It has been tested in the lab environment, the outdoor campus, and the volcano crater. Despite the heavy rain, snow, and ice as well as gusts exceeding 160 km per hour, the sensor network has achieved a remarkable packet delivery ratio above 99 percent with an overall system uptime of about 93.8 percent over the 1.5 months evaluation period after deployment. Our initial deployment experiences with the system demonstrated to discipline scientists that a low-cost sensor network system can support real-time monitoring in extremely harsh environments.
Molecular Cloning and Sequencing of thearoA Gene from Actinobacillus pleuropneumoniaeand Its Use in a PCR Assay for Rapid Identification

ABSTRACT The gene (aroA) of Actinobacillus pleuropneumoniae, serotype 2, encoding 5-enolpyruvylshikimate-3-phosphate synthase was cloned by complementation of the aroA mutation in Escherichia coli K-12 strain AB2829, and the nucleotide sequence was determined. A pair of primers from the 5′ and 3′ termini were selected to be the basis for development of a specific PCR assay. A DNA fragment of 1,025 bp was amplified from lysed A. pleuropneumoniaeserotypes 1 to 12 of biovar 1 or from isolated DNA. No PCR products were detected when chromosomal DNAs from other genera were used as target DNAs; however, a 1,025-bp DNA fragment was amplified whenActinobacillus equuli chromosomal DNA was used as a target, which could be easily differentiated by its NAD independence. The PCR assay developed was very sensitive, with lower detection limits of 12 CFU with A. pleuropneumoniae cells and 0.8 pg with extracted DNA. Specificity and sensitivity make this PCR assay a useful method for the rapid identification and diagnosis of A. pleuropneumoniae infections.
Biodistribution, Kinetics, and Efficacy of Highly Phosphorylated and Non-phosphorylated β-Glucuronidase in the Murine Model of Mucopolysaccharidosis VII*

Enzyme replacement therapy (ERT) has been shown to be effective at reducing the accumulation of undegraded substrates in lysosomal storage diseases. Most ERT studies have been performed with recombinant proteins that are mixtures of phosphorylated and non-phosphorylated enzyme. Because different cell types use different receptors to take up phosphorylated or non-phosphorylated enzyme, it is difficult to determine which form of enzyme contributed to the clinical response. Here we compare the uptake, distribution, and efficacy of highly phosphorylated and non-phosphorylated β-glucuronidase (GUSB) in the MPS VII mouse. Highly phosphorylated murine GUSB was efficiently taken up by a wide range of tissues. In contrast, non-phosphorylated murine GUSB was taken up primarily by tissues of the reticuloendothelial (RE) system. Although the tissue distribution was different, the half-lives of both enzymes in any particular tissue were similar. Both preparations of enzyme were capable of preventing the accumulation of lysosomal storage in cell types they targeted. An important difference in clinical efficacy emerged in that phosphorylated GUSB was more efficient than non-phosphorylated enzyme at preventing the hearing loss associated with this disease. These data suggest that both forms of enzyme contribute to the clinical responses of ERT in MPS VII mice but that enzyme preparations containing phosphorylated GUSB are more broadly effective than non-phosphorylated enzyme.
Racial differences in access to hierarchical authority : An analysis of change over time, 1972-1994

Using national data from the General Social Surveys, I examined race differences in the magnitude of the black-white gap among men in the odds of gaining access to positions of hierarchical authority at work and possible changes in this gap over the period 1972–1994. A test of William Julius Wilson's (1978) thesis of “the declining significance of race’and human capital/structural explanations for racial differences in access to hierarchical authority show that (1) blacks are less likely to be in the highest levels of job authority net of human capital, occupational location, family status, and region of residence, but there are fewer racial differences in access to lower positions of authority, and (2) blacks receive a lower authority return to their levels of education compared to whites. However, separate analyses based on subsamples of men living and working in large and small cities suggest that the racial gap in access to high authority and in the amount of authority returns to education is present more so among men living in large cities than small cities; but the racial gap in men's access to positions of high authority in small cities increased over the twenty-two-year period covered by the data. I discuss the implications of these findings for the persistent role of race in determining the life chances of black and white men.
Genetic influences on post-natal depressive symptoms: findings from an Australian twin sample

Background. Conflicting evidence exists on causes of vulnerability to post-natal depression. We investigated genetic and environmental influences on variation in post-natal depressive symptoms (PNDS) following first live birth, and sources of covariation with the personality trait Neuroticism and lifetime major depression occurring post-natally (DEP-PN) and at other times (DEP-XPN) to test for shared genetic influences. Method. Retrospective interview and questionnaire data from 838 parous female twin pairs (539 monozygotic, 299 dizygotic) from the Australian National Health and Medical Research Council volunteer adult twin register were used for multivariate genetic model-fitting. Data on PNDS were evaluated for consistency with diagnostic interview assessment. Results. Genetic factors explained 38% of variance in PNDS (95% confidence interval 26–49%) and 25% of the variance in interview-assessed DEP-PN. The genetic correlation between PNDS and lifetime major depression (DEP-PN and DEP-XPN) was low (rg = 0·17, 95% confidence interval = 0·09–0·28), suggesting that the questionnaire was measuring a construct other than post-natally occurring major depression, possibly post-natal dysphoria. Associations between PNDS and obstetric factors were very modest. Conclusions. Findings suggest modest genetic influences on major depression occurring post-natally. Independent and stronger genetic influences identified for post-natal symptomatology or dysphoria (PNDS) justify further investigation.
Dual role of lignin in plant litter decomposition in terrestrial ecosystems

Plant litter decomposition is a critical step in the formation of soil organic matter, the mineralization of organic nutrients, and the carbon balance in terrestrial ecosystems. Biotic decomposition in mesic ecosystems is generally negatively correlated with the concentration of lignin, a group of complex aromatic polymers present in plant cell walls that is recalcitrant to enzymatic degradation and serves as a structural barrier impeding microbial access to labile carbon compounds. Although photochemical mineralization of carbon has recently been shown to be important in semiarid ecosystems, litter chemistry controls on photodegradative losses are not understood. We evaluated the importance of litter chemistry on photodegradation of grass litter and cellulose substrates with varying levels of lignin [cellulose-lignin (CL) substrates] under field conditions. Using wavelength-specific light attenuation filters, we found that light-driven mass loss was promoted by both UV and visible radiation. The spectral dependence of photodegradation correlated with the absorption spectrum of lignin but not of cellulose. Field incubations demonstrated that increasing lignin concentration reduced biotic decomposition, as expected, but linearly increased photodegradation. In addition, lignin content in CL substrates consistently decreased in photodegradative incubations. We conclude that lignin has a dual role affecting litter decomposition, depending on the dominant driver (biotic or abiotic) controlling carbon turnover. Under photodegradative conditions, lignin is preferentially degraded because it acts as an effective light-absorbing compound over a wide range of wavelengths. This mechanistic understanding of the role of lignin in plant litter decomposition will allow for more accurate predictions of carbon dynamics in terrestrial ecosystems.
A field guide to boxology: preliminary classification of architectural styles for software systems

Software architects use a number of commonly-recognized "styles" to guide their design of system structures. Each of these is appropriate for some classes of problems, but none is suitable for all problems. How, then, does a software designer choose an architecture suitable for the problem at hand? Two kinds of information are required: (1) careful discrimination among the candidate architectures and (2) design guidance on how to make appropriate choices. In this paper, we support careful discrimination with a preliminary classification of styles. We use a 2D classification strategy with control and data issues as the dominant organizing axes. We position the major styles within this space and use finer-grained discriminations to elaborate variations on the styles. This provides a framework for organizing design guidance, which we partially flesh out with rules of thumb.
KINETICS OF THE INITIAL ROUNDS OF CELL DIVISION OF TOXOPLASMA GONDII

RH strain Toxoplasma gondii tachyzoites that had naturally lysed their host cells were allowed to infect new host cells for a limited amount of time; subsequent parasite cell divisions were observed closely. On the basis of 4 independent trials, the estimated time to first cell division was 9.8 hr postinfection (PI) and was quite variable (95% confidence interval [CI]: 3.1–16.5 hr PI). The estimated time to second cell division was 14.9 hr PI and was less variable (95% CI: 12.1–17.7 hr PI). Few parasites divided before 6 hr PI in these 4 trials. When tachyzoites were derived by forced lysis (scraping an infected host cell culture and passing it through 27-gauge needles), the first parasite cell division occurred much more rapidly than had been observed in any of the trials with parasites derived by natural lysis. When parasites derived by forced lysis were held away from host cells for 3 hr PI, the first cell division was delayed in a manner similar to that seen in parasites derived by natural lysis. No differences were observed in the timing of the second cell division of parasites derived by forced lysis whether or not they had been held away from cells. These studies demonstrate that the conditions to which tachyzoites are exposed during transit from one host cell to another can affect the kinetics of parasite cell division in the new host cell.
Portals and Task Innovation: A Theoretical Framework Founded on Business Intelligence Thinking

The main aim of this study is to develop a theoretical framework for the success of Web portals in promoting task innovation. This is deemed significant as yet little research has tackled this important domain from the business intelligence perspective. The D&M IS Success Model was used as a foundational theory and then was refined to match the context of the current research. Importantly, in this study, system quality and information quality constructs were defined on the basis of portals' characteristics since a mapping was conducted between the most significant functions and features of Web portals and quality constructs. The developed framework is deemed useful for theory and practice. From theoretical perspective, the dimensions that affect the perceived quality of Web portals are identified, and the measures that affect each quality dimension are also defined. On the practical level, contributions gained by this study can be observed in terms of the benefits decision makers, strategists, operational employees and IT developers can gain. Assessing portals success in improving task innovation is important to help managers (i.e. decision makers) in making appropriate decisions concerning the adoption of portals' technology, by weighing its benefits against the costs needed to establish and run such a technology. Moreover, assessing Web portals' success gives some insight to IT developers and designers concerning what aspects should be taken when designing and establishing high quality portals, and what functions and features should be contained that would affect the perceived quality of portals and therefore users' intention to use portals. Keywords: Web Portal, IS Success Model, Delone and Mclean Model, Task Innovation, Business Intelligence, Information Systems.
Indications and Complications of Tube Thoracostomy with Improvised Underwater Seal Bottles

Background: Tube thoracostomy is a lifesaving and frequently performed procedure in hospitals where the expertise and necessary tools are available. Where the ideal drainage receptacle is unavailable, the underwater seal device can be improvised with bottled water plastic can especially in emergency situations. Aims and Objectives: To determine the frequencies of the various indications and complications of tube thoracostomy with improvised underwater seal. Materials and Methods: A cross-sectional study with a structured proforma was used for assessment over a 3-year period (May 2010-April 2013). The proforma was filled at the time of the procedure by the performing surgeon and patients were followed up with serial chest X-rays until certified cured. A 1.5 L bottled water container was used as the underwater seal receptacle. The data was analysed with SPSS 15 software program. Results: A total of 167 patients were managed. There were 106 (63.5%) males and 61 (36.5%) females. The mean age was 34.85 ± 16.72 with a range of 1-80 years. The most frequent indication was for malignant/paramalignant effusion, 46 (27.5%). Others were trauma, 44 (26.3%), Parapneumonic effusion, 20 (12%), postthoracotomy 14 (8.4%), empyema thoracis 12 (7.2%), heart disease and tuberculous effusion 11 (6.6%) each, pneumothorax 8 (4.8%) and misdiagnosis 1 (0.6%). A hundred and one (60.5%) of the procedures were performed by registrars, 41 (24.6%) by consultants, house officers 15 (9%) and senior registrars 10 (6%). The overall complication rate was 16.8% with the more frequent complications been empyema (5.6%) and pneumothorax (3.6%). The average duration of tube placement was 13.02 ± 12.362 days and range of 1-110 days. Conclusion : Tube thoracostomy can be a relatively safe procedure with acceptable complication rates even with improvised underwater seal drainage bottles.
Muscle Glycogen Synthesis and Disposition of Infused Glucose in Humans With Reduced Rates of Insulin-Mediated Carbohydrate Storage

Six men with a low rate of insulin-stimulated, non-oxidative carbohydrate disposal (storage) and six with a high storage rate were recruited for study of the fate of insulin-stimulated glucose uptake. [3-3H]glucose was infused before and during a 4-h hyperinsulinemic euglycemic clamp procedure in a dosage regimen designed to maintain a constant specific activity. From the disposition of label, the rate of insulin-mediated glucose incorporation into glycogen in the low-storage subjects was one-fourth that of the high-storage subjects (P < .02). The insulin-mediated increase in muscle glycogen synthase activity in the low-storage subjects was one-fourth that of the high-storage subjects (P < .05), suggesting the possibility of a causal relationship. In the high-storage but not the low-storage subjects, the rate of glycolysis inferred from the appearance of metabolized tritium in body water exceeded the carbohydrate oxidation rate (P < .002). This suggests that in these subjects there is a significant fraction of glycolysis that is not oxidized and that this component of carbohydrate metabolism therefore contributes to storage.
Early mortality after neonatal surgery: analysis of risk factors in an optimized health care system for the surgical newborn.

OBJECTIVE Anesthetic and operative interventions in neonates remain hazardous procedures, given the vulnerability of the patients in this pediatric population. The aim was to determine the preoperative and intraoperative factors associated with 30-day post-operative mortality and describe mortality outcomes following neonatal surgery under general anesthesia in our center. METHODS Infants less than 28 days of age who underwent general anesthesia for surgery during an 11-year period (2000 - 2010) in our tertiary care pediatric center were retrospectively identified using the pediatric intensive care unit database. Multiple logistic regression was used to identify independent preoperative and intraoperative factors associated with 30-day post-operative mortality. RESULTS Of the 437 infants in the study (median gestational age at birth 37 weeks, median birth weight 2,760 grams), 28 (6.4%) patients died before hospital discharge. Of these, 22 patients died within the first post-operative month. Logistic regression analysis showed increased odds of 30-day post-operative mortality among patients who presented American Society of Anesthesiologists physical status (ASA) score 3 or above (odds ratio 19.268; 95%CI 2.523 - 147.132) and surgery for necrotizing enterocolitis/gastrointestinal perforation (OR 5.291; 95%CI 1.962 - 14.266), compared to those who did not. CONCLUSION The overall in-hospital mortality of 6.4% is within the prevalence reported for developed countries. Establishing ASA score 3 or above and necrotizing enterocolitis/gastrointestinal perforation as independent risk factors for early mortality in neonatal surgery may help clinicians to more adequately manage this high risk population.
A prototype for convective margin shifts

Regional precipitation anomalies under El Niño or global warming scenarios manifest considerable spatial variability, especially in the vicinity of tropical deep convective zones. Using a simplified set of equations, we develop an analytic prototype of convective margins for tropical land regions subject to inflow from adjacent ocean regions. The approach yields an expression for the location of the convective margin from which it is straightforward to deduce how climate perturbations impact the margin. We compare the results of the prototype to full model simulations of the equatorial South American precipitation response to El Niño forcing and find general agreement. Analysis of the observations supports the convective inflow margin prototype's applicability to appropriately simple basic state configurations.
Survey of smoking knowledge, attitudes and practice in school children in Honduras.

OBJECTIVE The aim of this study was to survey Honduran pre-adolescent knowledge, perceptions and experience regarding smoking. METHODS A 12-item survey was administered in the classroom to fifth and sixth grade students. The main outcome measures were a description of demographic factors, personal smoking experience, knowledge of health risks, attitudes about tobacco use and perceived sources of information. RESULTS A total of 225 students were surveyed. The majority were aware that smoking is bad for health, and most reported never having smoked. Most viewed smoking as ugly. Friends and family were selected as the major source of information. CONCLUSIONS School children in this area of Honduras are aware of the health risks of smoking and view smoking as unattractive.