Miracle-dz/UniFAR-FTUs huggingface dataset:
Busyness and Citizenship

H O W DOES TH E EXPERIENCE OF BUSYNESS AFFECT DEMOCRATIC POLITICAL life? My hunch is that those reading this essay m ight very w ell offer the following answer: busyness means that w e relegate political activities to the bottom o f a long and som etim es tedious laundiy list o f “things to get done. ” In fact, many o f us no longer even bother to include the basic activities o f citizenship—becom ing inform ed about the issues, delib­ erating w ith our peers about matters o f com m on concern, attending a political m eeting, or even voting—on the list in the first place. Like this author, many readers probably feel som ewhat guilty about this as well, and thus tiy to com pensate in some way or another. Rather than volun­ teering for a presidential campaign, for example, I spend a few minutes writing out a check to the candidate or campaign o f my choice. Even better (because it’s less tim e consuming), I go online and provide my credit card number and make a donation that is transmitted in a matter o f nanoseconds. I make up for the fact that m y day is already crammed full w ith tim e-consum ing activities by privileging forms o f political activity that can be engaged in rapidly and even instantaneously. At worst, busyness generates political disinterest and apathy: many o f our fellow citizens openly describe the m ost fundam ental form o f dem o­ cratic participation, the vote, as a “w aste o f tim e. ” At best, it seem s to privilege an acceleration o f political activity: w e seek speedy and rapidly consummated types o f involvem ent that do not unduly add to the enormous tim e pressures w e already feel. Unfortunately, it remains unclear whether even such high-speed forms o f citizen involvem ent are
A Model of Antecedents of RFID Adoption Intention in the Supply Chain

The application of the Radio Frequency Identification (RFID) technology in the supply chain has experienced increased attention in academic research and practice. There is, however, a research gap on antecedents of RFID adoption intention which impedes an assessment of RFID diffusion in the future. This study elaborates a structural model based on the technology-organization-environment framework and incorporates an economic perspective and the concept of need-pull to investigate antecedents of RFID adoption intention by firms. The results from a quantitative survey in a European Fast Moving Consumer Goods (FMCG) market indicate that perceived internal and interorganizational benefits as well as expected future costs of RFID are significant drivers. The need-pull shows a partly mediated effect, whereas firm size and applied technologies show no impact on RFID adoption intention.
Polymorphism of Alcohol Metabolizing Gene ADH3 Predisposes to Development of Alcoholic Pancreatitis in North Indian Population

Background and aim: Genetic factors regulating alcohol metabolism could predispose in developing alcoholic pancreatitis (ACP). Studies revealed that alcohol could be metabolized by both ways, oxidative and non-oxidative. The main oxidative pathway includes alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), and cytochrome P450 enzyme. We investigated the association of polymorphisms in these enzymes with the alcoholic pancreatitis in the north Indian population. Method: Patients with alcoholic pancreatitis (ACP; n = 72), tropical calcific pancreatitis (TCP; n = 75), alcoholic controls (AC; n = 40), and healthy controls (HC; n = 100) were included in the study. Blood samples were collected from the subjects in EDTA coated vials. DNA was extracted and genotyping for ADH3, ALDH2, and CYP2E1 was done by PCR-RFLP (polymerase chain reaction—restriction fragment length polymorphism). The products were analyzed by gel electrophoresis. Result: The frequency distribution of ADH3*1/*1 genotype was significantly higher in ACP group (59.7%) compared with TCP (38.7%), HC (42%), and AC (37.5%) and was found to be associated with increased risk of alcoholic pancreatitis. There was no statistically significant difference between the frequency distribution of ADH3*1/*1, ADH3*1/*2, and ADH3*2/*2 genotypes between TCP and HC or healthy alcoholics. ALDH2 gene was monomorphic in our population, and the frequencies for CYP2E1 intron 6 Dra I polymorphism were comparable in all the four groups. Conclusion: This study shows that carriers of ADH3*1/*1 individuals consuming alcohol are at higher risk for alcoholic pancreatitis than those with other genotypes such as ADH3*1/*2 and ADH3*2/*2.
Association of a STAT 6 haplotype with elevated serum IgE levels in a population based cohort of white adults

Background: Several studies have shown linkage of chromosome 12q 13–24 with atopy related phenotypes. Among candidate genes in this region is STAT6 (signal transducer and activator of transcription), which is essential for Th2 cell differentiation, recruitment, and effector function. Methods: We evaluated six polymorphisms of STAT6 for evidence of associations with serum IgE levels and atopic diseases in a population based cross sectional cohort of 1407 German adults. Genotyping was performed using the matrix assisted laser desorption ionisation–time of flight mass spectrometry method. Haplotypes were estimated using the SAS/Genetics module, and population-derived IgE percentiles (50% IgE>53 kU/l, 66% IgE>99 kU/l and 90% IgE>307 kU/l) were modelled as outcome variables in haplotype trend regression analysis. Results: All polymorphisms were genotyped successfully. Haplotype reconstruction revealed 8/64 possible haplotypes, reaching estimated frequencies of 1% or more. One polymorphism in intron 2 (rs324011) showed a significant association with total serum IgE (p = 0.015). A STAT6 risk haplotype for elevated IgE showing odds ratios of 1.7 (p = 0.015) for IgE cut-off 100 kU/l, and 1.54 (p = 0.032), 1.6 (p = 0.025), and 2.54 (p = 0.007) for IgE percentiles 50%, 66%, and 90%, respectively was detected. The increased risk of this haplotype was confirmed by linear haplotype trend regression on log transformed IgE values (p = 0.007). Analysis further revealed a risk haplotype for specific sensitisation and a risk haplotype for asthma. Conclusion: The data indicate that genetic variants within STAT6 contribute significantly to IgE regulation and manifestation of atopic diseases.
Processing in the encrypted domain using a composite signal representation: Pros and cons

The current solutions for secure processing in the encrypted domain are usually based on homomorphic cryptosystems operating on very large algebraic structures. Recently, a composite signal representation has been proposed that allows to speed up linear operations on encrypted signals via parallel processing and to reduce the size of the encrypted signals. Though many of the most common signal processing operations can be applied to composite signals, some operations require to process the signal samples independently from each other, thus requiring an unpacking of the composite signals. In this paper, we will address the above issues, showing both merits and limits of the composite signal representation when applied in practical scenarios. A secure protocol for converting an encrypted composite representation into the encryptions of the single signal samples will be introduced. A case study clearly highlights pros and cons of using the composite signal representation in the proposed scenarios.
Support Vector Machine Technique for the Short Term Prediction of Travel Time

A vast majority of urban transportation systems in North America are equipped with traffic surveillance systems that provide real time traffic information to traffic management centers. The information from these are processed and provided back to the travelers in real time. However, the travelers are interested to know not only the current traffic information, but also the future traffic conditions predicted based on the real time data. These predicted values inform the drivers on what they can expect when they make the trip. Travel time is one of the most popular variables which the users are interested to know. Travelers make decisions to bypass congested segments of the network, to change departure time or destination etc., based on this information. Hence it is important that the predicted values be as accurate as possible. A number of different forecasting methods have been proposed for travel time forecasting including historic method, real-time method, time series analysis, and artificial neural networks (ANN). This paper examines the use of a machine learning technique, namely support vector machines (SVM), for the short-term prediction of travel time. While other machine learning techniques, such as ANN, have been extensively studied, the reported applications of SVM in the field of transportation engineering are very few. A comparison of the performance of SVM with ANN, real time, and historic approach is carried out. Data from the TransGuide Traffic Management center in San Antonio, Texas, USA is used for the analysis. From the results it was found that SVM is a viable alternative for short-term prediction problems when the amount of data is less or noisy in nature.
Gender Differences in Negotiation: Considering the Usual Driving Forces?

: Negotiation is a specific form of interaction based on communication in which the parties enter into deliberately, each with clear but different interests or goals and a mutual dependency towards a decision due to be taken at the end of the confrontation. Consequently, negotiation is a complex activity involving many different disciplines from the strategic aspects and the decision making process to the evaluation of alternatives or outcomes and the exchange of information. While gender differences can be considered as one of the most researched topic within negotiation studies, empirical works and theory present many conflicting evidences and results about the role of gender in the process or the outcome. Furthermore, little interest has been shown over gender differences in the definition of what is negotiation, its essence or fundamental elements. Or, as differences exist in practices, it might be essential to study if the starting point of these discrepancies does not come from different considerations about what is negotiation and what will encourage the participants in their strategic decisions. Some recent and promising experiments made with diverse groups show that male and female participants in a common and shared situation barely consider the same way the concepts of power, trust or stakes which are largely considered as the usual driving forces of any negotiation. Furthermore, results from Human Resource self-assessment tests display and confirm considerable differences between individuals regarding essential behavioral dimensions like capacity to improvise and to achieve, aptitude to conciliate or to compete and orientation towards power and group domination which are also part of negotiation skills. Our intention in this paper is to confront these dimensions with negotiation’s usual driving forces in order to build up new paths for further research.
Midterm Results of Surgical Hip Dislocation for the Treatment of Femoroacetabular Impingement

Background: Surgical treatment of femoroacetabular impingement (FAI) includes both open and arthroscopic procedures. Encouraging results have been reported for the majority of patients after surgical hip dislocation; however, most of these reports were short term and included only small cohorts. Purpose: To determine the results of surgical hip dislocation in a large cohort of FAI patients at a midterm follow-up. Study Design: Case series; Level of evidence, 4. Methods: A retrospective study including 185 consecutive patients (mean age, 30 years; 40% female) with 233 hips treated was conducted. We determined clinical outcomes in terms of range of motion and analyzed radiographs for several criteria including the alpha angle preoperatively and at 1 year postoperatively. At latest follow-up, on average 61 months postoperatively, patient satisfaction, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Hip Outcome Score, SF-12, and University of California, Los Angeles (UCLA) activity scale scores were determined. All revisions and conversions to total hip arthroplasty (THA) were recorded. Results: Both hip flexion and internal rotation improved from preoperatively to postoperatively. Alpha angles decreased from 65.1° ± 14.2° to 42.4° ± 4.9°. At 5 years, 82% of the patients were satisfied or very satisfied with the results of surgery, and 81% would undergo the same surgery again. There were 83% who rated their overall hip function as normal or nearly normal. Mean scores for the WOMAC pain, stiffness, and function subscales were 10.3 ± 15.8, 15.9 ± 17.4, and 9.6 ± 13.0 points; for Hip Outcome Score activities of daily living and sport subscales were 89.0 ± 13.1 and 75.6 ± 23.0 points; and for the SF-12 Physical Component Scale and Mental Component Scale were 47.4 ± 6.3 and 52.3 ± 7.4 points, respectively. The mean UCLA activity level was 7.7 ± 1.9. Conversion to THA was performed in 7 hips (3%). Seven hips (3%) underwent other major revisions, and 11 (4.7%) underwent minor revisions. Female patients had a significantly increased risk for conversion to THA (odds ratio, 13.3; 95% confidence interval [CI], 1.3-92.6) and major revision (odds ratio, 19.2; 95% CI, 2.4-152.9). The mean body mass index was significantly lower in those patients who underwent conversion to THA. The need for microfracture because of residual full-thickness cartilage defects after rim trimming was a significant (P = .04) predictor of subjective dissatisfaction. Conclusion: This study demonstrates that surgical hip dislocation is a successful procedure for the treatment of FAI. A majority of patients were satisfied with the results of surgery at a midterm follow-up. Older and slim female patients were at an increased risk for a less successful outcome in terms of conversion to THA and revision surgery.
Effects of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Type 1 Receptor Antagonist in Deoxycorticosterone Acetate–Salt Hypertensive Mice Lacking Ren-2 Gene

We previously reported that inhibition of angiotensin-converting enzyme (ACE) prevented the hypertension and left ventricular hypertrophy induced by deoxycorticosterone acetate–salt (DOCA-salt) in 129/SvEvTac mice, which have 2 renin genes (Ren-1 and Ren-2). In the present study, we induced hypertension by uninephrectomy and DOCA-salt in mice having only the Ren-1 gene (C57BL/6J) and investigated the effect of an ACE inhibitor (ramipril, 4 mg · kg−1 · d−1) and an angiotensin type 1 (AT1) receptor antagonist (L-158809, 4 mg · kg−1 · d−1) on the development of hypertension, cardiac hypertrophy, and renal injury. After 4 weeks of treatment, systolic blood pressure in DOCA-salt mice was significantly increased (128±2 mm Hg) compared with controls (109±2 mm Hg) (P <0.001), while plasma renin concentration was decreased by 97% (P <0.001). DOCA-salt also induced left ventricular and renal hypertrophy and renal damage as manifested by proteinuria. Collagen content in the left ventricle and kidney was significantly higher in DOCA-salt mice (P <0.001). Urinary albumin (P <0.05) and proliferating cell nucleic antigen–positive cells in the tubules and interstitium of the renal cortex (P <0.001) were significantly increased in the DOCA-salt group. Neither the ACE inhibitor nor the AT1 antagonist had any antihypertensive effect; however, they partially prevented cardiac hypertrophy and completely inhibited left ventricular collagen deposition. In the kidney, both the ACE inhibitor and AT1 antagonist partially reduced the increase in collagen but had no effect on hypertrophy. They also significantly prevented the effect of DOCA-salt on urinary albumin and proliferating cell nucleic antigen expression in the kidney. Despite the lack of an antihypertensive effect, both ACE inhibitor and AT1 antagonist prevented cardiac remodeling and renal damage. Our results indicate that ACE inhibitors and AT1 antagonists exert beneficial effects on the heart and kidney in DOCA-salt hypertensive mice independently of their effects on blood pressure.
Transcoronary Concentration Gradients of Circulating MicroRNAs

Background— Circulating levels of microRNA (miR) have been proposed as biomarkers for cardiovascular disease. To identify the heart as a potential source for miRs released into the circulation, we measured concentration gradients across the coronary circulation for muscle-enriched (miR-133a, miR-499, miR-208a), vascular (miR-126, miR-92a), leukocyte-related (miR-155), and platelet-enriched (miR-223) miRs. Methods and Results— Circulating miRs were measured by TaqMan polymerase chain reaction in EDTA-plasma simultaneously obtained from the aorta and the coronary venous sinus in patients without coronary artery disease (n=7), with stable coronary artery disease (n=31), and with troponin-positive acute coronary syndromes (n=19). Circulating levels of the muscle-enriched miR-499 (>20-fold; P<0.01), miR-133a (11-fold; P<0.01), and miR-208a (5-fold; P<0.01) were significantly elevated in the aorta of troponin-positive acute coronary syndrome patients compared with patients with coronary artery disease. Importantly, there was a significant increase in circulating levels of miR-499 and miR-133a across the coronary circulation in troponin-positive acute coronary syndrome patients, suggestive of a release into the coronary circulation during myocardial injury. Indeed, miR-499 concentration gradients were significantly correlated with the extent of myocardial damage as measured by high-sensitivity troponin T (r=0.70, P<0.01). In contrast, circulating levels of miR-126 (P=0.16) decreased during transcoronary passage in patients with evidence of myocardial injury, suggesting consumption during transcoronary passage. Conclusions— Muscle-enriched miR-499 and miR-133a are released from the heart into the coronary circulation on myocardial injury, whereas the vascular miR-126 is consumed during transcoronary passage. The differential regulation of circulating miRs during the transcoronary passage might provide important insights to exploit their role as cardiac biomarkers. Clinical Trial Registration— URL: http://www.germanctr. de. Unique identifier: DRKS00000207; in German Clinical Trials Registry.
An evaluation of several measures of attention and inhibition in ten year old children

Due to numerous definitions for attention and inhibition, it is very difficult to operationalize and measure these constructs (Barkley, 1996). The primary purpose of this study was to determine whether there is evidence for independence between attention and inhibition constructs using measures from the TEA-ch, Gordon CPT, Stroop Task, WISCDigit Span and Go-No-Go Tasks and tasks of inhibition. Each of 140 students were evaluated on all measures and scores were correlated. In addition, Teacher Ratings and scores from the OLSAT were also correlated with attention and inhibition scores. Gender differences between all scores were also examined. Overall, measures did not correlate as expected. Results showed that there were significant but weak correlations among the sustained and selective attention variables. Similarly, when all inhibition variables were correlated only four significant but weak correlations were found. The lack of convergent validity and low correlations among these measures suggest that attention and inhibition constructs may be multi-dimensional. Intercorrelations between attention and inhibition variables were also weak. Relationships between OLSAT scores, Teachers Ratings and attention and inhibition variables showed that as scores that reflect reasoning skills and Teacher Ratings increased, the ability to attend and inhibit also increased. Gender differences in attention and inhibition scores were also examined and showed that girls were better at paying attention to stimuli and inhibiting impulsive responses than boys.
Tourette Syndrome

A retrospective analysis of a 35-year single-center experience with pediatric tics and Tourette syndrome was conducted. 482 charts from 1972 to 2007 were reviewed. Follow-up surveys were mailed to last known address and 83 patients responded (17%). Response rate was affected by long interval from last visit; contact information was often incorrect as it was the address of the patient as a child. Males constituted 84%. Mean tic onset was 6.6 years. At first visit, 83% had multiple motor tics and >50% had comorbidities. 44% required only 1 visit and 90% less than 12 visits. Follow-up showed positive clinical and social outcomes in 73/83 survey responses. Of those indicating a poor outcome, mean educational level was lower and attention deficit/hyperactivity disorder and learning disabilities were significantly higher. Access to knowledgeable caregivers was a problem for adult patients. A shortage of specialists may in part be addressed by interested general pediatricians.
Molecular Identification of Giardia intestinalis in Patients with Dyspepsia

Background/Aims:Giardia intestinalis triggers symptoms of functional dyspepsia. The aim of this study was to distinguish genotypes of G. intestinalis isolated from dyspeptic patients to evaluate their correlation with dyspeptic symptoms. Methods: In total, 120 dyspeptic subjects were investigated by upper endoscopy, including gastric and duodenal biopsies for histopathological examination, and parasitological examination of their stools and duodenal aspirates was performed. The patients were classified into five groups: group I (G. intestinalis) included 19 patients, group II (Helicobacter pylori) included 36 patients, group III (coeliac disease) included 3 patients, group IV (mixed G. intestinalis and H. pylori infection) included 4 patients, and group V (unexplained aetiology) included 58 patients. Genotyping of G. intestinalis was performed for groups I and IV using PCR-RFLP. The urease test was performed for H. pylori. Serum anti-gliadin, anti-endomysial and anti-transglutaminase antibody estimation was performed for the diagnosis of coeliac disease. Results: Genotype A of G. intestinalis was detected in the stool samples of 68.42% (13/19) and the duodenal aspirates of 42.1% (8/19) of dyspeptic patients harbouring the parasite. Genotype B was detected in 31.58% (6/19) of cases in stool samples and in 3 cases in duodenal aspirates. Conclusions:H. pylori, G. intestinalis and coeliac disease are common causes of dyspepsia. G. intestinalis genotype A demonstrated a greater association with dyspeptic symptoms.