Miracle-dz/UniFAR-FTUs huggingface dataset:
Adiabatic Quantum State Generation

The design of new quantum algorithms has proven to be an extremely difficult task. This paper considers a different approach to this task by studying the problem of quantum state generation. We motivate this problem by showing that the entire class of statistical zero knowledge, which contains natural candidates for efficient quantum algorithms such as graph isomorphism and lattice problems, can be reduced to the problem of quantum state generation. To study quantum state generation, we define a paradigm which we call adiabatic state generation (ASG) and which is based on adiabatic quantum computation. The ASG paradigm is not meant to replace the standard quantum circuit model or to improve on it in terms of computational complexity. Rather, our goal is to provide a natural theoretical framework, in which quantum state generation algorithms could be designed. The new paradigm seems interesting due to its intriguing links to a variety of different areas: the analysis of spectral gaps and ground-states of Hamiltonians in physics, rapidly mixing Markov chains, adiabatic computation, and approximate counting. To initiate the study of ASG, we prove several general lemmas that can serve as tools when using this paradigm. We demonstrate the application of the paradigm by using it to turn a variety of (classical) approximate counting algorithms into efficient quantum state generators of nontrivial quantum states, including, for example, the uniform superposition over all perfect matchings in a bipartite graph.
Worldwide diversity of hair curliness: a new method of assessment

Background For many years, cosmetic scientists have attempted to measure the physical features of human hair, such as its shape and colour, as these can be artificially modified using cosmetic products. With regard to hair shape, previous anthropologic studies have emphasized its variability within and between human ethnic groups. Many studies have broadly distinguished three ethnic human subgroups: African, Asian, and Caucasian. Such a broad classification cannot account for the great complexity of human biological diversity, resulting from multiple, past or recent mixed origins. The verbal description of hair shape ranges from the classic to the more sophisticated, with terms such as straight, wavy, curly, frizzy, kinky, woolly, helical, etc. Although these descriptions evoke a global appearance, they remain confusing as their definitions and limits are unclear. Assessments are therefore required to more accurately define such verbal attributes.
Single-Column Modeling

Cloud-climate interactions are one of the greatest uncertainties in contemporary general circulation models (GCMs) (Cess et al. 1989, 1990), and the present study has focused on one aspect of this. Specifically, combined satellite and near-surface shortwave (SW) flux measurements have been used to test the impact of clouds on the SW radiation budget of two GCMs. Concentration is initially on SW rather than longwave (LW) radiation because, as will be discussed shortly, in one of the GCMs used in this study an SW radiation inconsistency causes, at least in part, a LW inconsistency. Thus, there~is no logic in testing the LW cloud interactions until the SW problem has been rectified.
On the Equivalence of Holographic and Complex Embeddings for Link Prediction

We show the equivalence of two state-of-the-art models for link prediction/knowledge graph completion: Nickel et al’s holographic embeddings and Trouillon et al.’s complex embeddings. We first consider a spectral version of the holographic embeddings, exploiting the frequency domain in the Fourier transform for efficient computation. The analysis of the resulting model reveals that it can be viewed as an instance of the complex embeddings with a certain constraint imposed on the initial vectors upon training. Conversely, any set of complex embeddings can be converted to a set of equivalent holographic embeddings.
T-type calcium channel Cav3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants

The fine-tuning of neuronal excitability relies on a tight control of Ca2+ homeostasis. The low voltage-activated (LVA) T-type calcium channels (Cav3.1, Cav3.2 and Cav3.3 isoforms) play a critical role in regulating these processes. Despite their wide expression throughout the central nervous system, the implication of T-type Cav3.2 isoform in brain functions is still poorly characterized. Here, we investigate the effect of genetic ablation of this isoform in affective disorders, including anxiety, cognitive functions as well as sensitivity to drugs of abuse. Using a wide range of behavioral assays we show that genetic ablation of the cacna1h gene results in an anxiety-like phenotype, whereas novelty-induced locomotor activity is unaffected. Deletion of the T-type channel Cav3.2 also triggers impairment of hippocampus-dependent recognition memories. Acute and sensitized hyperlocomotion induced by d-amphetamine and cocaine are dramatically reduced in T-type Cav3.2 deficient mice. In addition, the administration of the T-type blocker TTA-A2 prevented the expression of locomotor sensitization observed in wildtype mice. In conclusion, our data reveal that physiological activity of this specific Ca2+ channel is required for affective and cognitive behaviors. Moreover, our work highlights the interest of T-type channel blockers as therapeutic strategies to reverse drug-associated alterations.
A state-space mixed membership blockmodel for dynamic network tomography

In a dynamic social or biological environment, the interactions between the actors can undergo large and systematic changes. In this paper we propose a model-based approach to analyze what we will refer to as the dynamic tomography of such time-evolving networks. Our approach offers an intuitive but powerful tool to infer the semantic underpinnings of each actor, such as its social roles or biological functions, underlying the observed network topologies. Our model builds on earlier work on a mixed membership stochastic blockmodel for static networks, and the state-space model for tracking object trajectory. It overcomes a major limitation of many current network inference techniques, which assume that each actor plays a unique and invariant role that accounts for all its interactions with other actors; instead, our method models the role of each actor as a time-evolving mixed membership vector that allows actors to behave differently over time and carry out different roles/functions when interacting with different peers, which is closer to reality. We present an efficient algorithm for approximate inference and learning using our model; and we applied our model to analyze a social network between monks (i.e., the Sampson's network), a dynamic email communication network between the Enron employees, and a rewiring gene interaction network of fruit fly collected during its full life cycle. In all cases, our model reveals interesting patterns of the dynamic roles of the actors.
Intranasal versus intravenous lorazepam for control of acute seizures in children: A randomized open‐label study

Purpose: Intravenous lorazepam is considered the drug of first choice for control of acute convulsive seizures. However, resource or personnel constraints necessitate the study of alternative routes and medications. This study compared the efficacy and adverse effects of intranasal versus intravenous lorazepam in children aged 6–14 years who presented with acute seizures.
Developmental changes in the variability of tongue and lip movements during speech from childhood to adulthood: An EMA study

This study investigated the developmental variability of lip and tongue movement in 48 children and adults. Motion of the tongue-tip, tongue-body and lower lip was recorded using electromagnetic articulography during productions of sentences containing /t/, /s/, /l/, /k/ and /p/. Four groups of speakers participated in the study: (1) aged 6–7 years; (2) 8–11 years; (3) 12–17 years; and (4) adults. The variation in distance, duration, speed, acceleration and deceleration of the articulators during single open–close speech movements was analysed, and the stability of multiple movement sequences was examined using the spatiotemporal index. The experimental findings revealed a gradual developmental progression from 6 years to adulthood. At adolescence, speakers continued to exhibit significantly more variable speech motor output compared to adult speakers. The observed developmental pattern suggests that attenuated, but important, changes in the speech motor system occurs from mid-childhood, through adolescence, to adulthood.
Childhood intussusception: the implications of delayed presentation.

BACKGROUND In some developing countries, many children with intussusception are reported to present late for definitive therapy. This study determines the effect of delayed presentation on clinical parameters, management, and outcome of childhood intussusception in southeast Nigeria. METHODS Comparative analysis of 87 consecutive children with intussusception managed from January 1998 to December 2007 at the University of Nigeria Teaching Hospital, Enugu, was done. RESULTS Overall, the mean time from onset to presentation was 3.0 days (range 4 hours to 7 days). Thirteen (14.9%) presented within 24 hours of symptoms (group 1) and 74 (85.1%) presented after 24 hours (group 2). Clinical presentations were similar in the children with the exception of bilious vomiting, rectal bleeding, and abdominal distension which were significantly commoner in group 2 children (P < 0.05). Type of intussusception found at operation did not differ in the groups, but cases in group 2 had higher incidence of bowel complications, and greater risk of failed operative reduction and bowel resection than group 1 patients (P < 0.05). Though the postoperative complications did not differ significantly between the two groups, mortality directly related to intussusception occurred only in patients who presented after 24 hours. CONCLUSION Significant number of children with intussusception in our setting presented late for definitive treatment. These cases have a higher risk of bowel complications and intestinal resection. Outcome in these patients might be enhanced through improved perioperative care in the short term, or by improving access to, and reducing delays in seeking health care, in the long run.
Analysis of Publication Status of Abstracts Presented at the Annual Meeting of the Korean Academy of Rehabilitation Medicine

Objective To analyze publication rate, time to publication and the characteristics of the abstracts presented at the annual Korean Academy of Rehabilitation Medicine (KARM) meetings. Methods A total of 1,027 abstracts presented at the 2008 and 2009 annual KARM meetings were enrolled in the database and searched for their subsequent citation in PubMed, KoreaMed, and Google Scholar. Results The data analysis revealed that 317 (30.87%) abstracts, were published as full-length journal articles and publication rates by subject were not significantly different. The mean time to publication was 17.17±10.48 months, and the journals written in English (20.39±10.20) required a longer duration than those written in Korean (11.94±8.44) with statistical significance (p<0.001). There was no statistical difference (p=0.284) in the duration between domestic (17.61±10.37) and foreign (16.48±10.51) of the 220 domestic journal articles, 190 (86.76%) were published in the Annals of Rehabilitation Medicine and the 97 articles published in foreign journals were scattered over 60 different journals. Conclusion The publication rate of abstracts presented at the 2008 and 2009 annual KARM meetings was 30.87% and the mean time to publication was 17.17±10.48 months.
Tailored supplemental screening for breast cancer: what now and what next?

OBJECTIVE This article reviews breast cancer risk assessment and the rationale for current screening guidelines, including when to consider using supplemental screening with MRI or sonography in addition to mammography, and discusses other emerging technologies. Radiologists can help identify women who may benefit from supplemental screening and can help to recommend when and which techniques to perform for this additional screening. CONCLUSION Mammography remains the mainstay of breast cancer screening. Mammography should be performed as digital imaging when possible in women with dense breasts. In women at high risk, particularly if they also have dense breasts, annual MRI is recommended, although further validation of outcomes is needed. In intermediate-risk women with dense breasts, especially those with other risk factors, and in high-risk women with dense breasts who are unable to tolerate MRI, supplemental sonography screening is an option at facilities with availability of qualified personnel. Developing technologies are not appropriate for screening at this time, although further study is encouraged.
Safety, efficacy, and patient acceptability of rifaximin for hepatic encephalopathy

Hepatic encephalopathy is a complex disease entity ranging from mild cognitive dysfunction to deep coma. Traditionally, treatment has focused on a reduction of ammonia through a reduced production, absorption, or clearance. Rifaximin is a nonabsorbable antibiotic, which reduces the production of ammonia by gut bacteria and, to some extent, other toxic derivatives from the gut. Clinical trials show that these effects improve episodes of hepatic encephalopathy. A large randomized trial found that rifaximin prevents recurrent episodes of hepatic encephalopathy. Most patients were treated concurrently with lactulose. Trials have varied greatly in design, outcomes, and duration of treatment regimes. Although a number of retrospective studies have indicated that long-term treatment with rifaximin is safe and possibly beneficial, high quality trials are needed to further clarify efficacy and safety of long-term treatment with rifaximin and evaluate effects of combination therapy with lactulose and branched-chain amino acids for patients with liver cirrhosis and hepatic encephalopathy.
Evidence for the eta_b(1S) Meson in Radiative Upsilon(2S) Decay

We have performed a search for the eta_b(1S) meson in the radiative decay of the Upsilon(2S) resonance using a sample of 91.6 million Upsilon(2S) events recorded with the BABAR detector at the PEP-II B factory at the SLAC National Accelerator Laboratory. We observe a peak in the photon energy spectrum at E_gamma = 609.3 {+4.6} {-4.5} (stat) +/- 1.9 (syst) MeV, corresponding to an eta_b(1S) mass of 9394.2 {+4.8} {-4.9} (stat) +/- 2.0 (syst) MeV/c^2. The branching fraction for the decay Upsilon(2S) -->gamma eta_b(1S) is determined to be [3.9 +/-1.1 (stat) {+1.1} {-0.9} (syst)] x 10^(-4). We find the ratio of branching fractions B[Upsilon(2S) -->gamma eta_b(1S)]/B[Upsilon(3S) -->gamma eta_b(1S)] = 0.82 +/- 0.24 (stat) {+0.20}{-0.19} (syst).
Correlation Between Increased Urinary Sodium Excretion and Decreased Left Ventricular Diastolic Function in Patients with Type 2 Diabetes Mellitus

Increased salt intake may induce hypertension, lead to cardiac hypertrophy, and exacerbate heart failure. When elderly patients develop heart failure, diastolic dysfunction is often observed, although the ejection fraction has decreased. Diabetes mellitus (DM) is an established risk factor for heart failure. However, little is known about the relationship between cardiac function and urinary sodium excretion (U‐Na) in patients with DM.
Analytical analysis of access-schemes of the CSMA type

This paper introduces an analytical approach for the analysis of medium access protocols of the CSMA type, which are used in many control networks. In contrast to known approaches the proposed technique considers systems with different customer classes and class specific arrival rates. Analysis is based on a decomposition approach, which determines class specific measures from the repeated analysis of isolated queues, which are coupled by a joint computation of service rates depending on the utilization of all queues. The results presented in this paper can be used as building blocks in product form algorithms for the analytical analysis of large systems consisting of several network segments connected via routers or bridges.
Violet light causes photodegradation of wood beyond the zone affected by ultraviolet radiation

Abstract The limited penetration of wood by light explains why the weathering of wood exposed outdoors is a surface phenomenon. Wood is rapidly degraded by short-wavelength UV radiation, but the penetration of light into wood is positively correlated with its wavelength. Hence, sub-surface degradation is likely to be caused by longer-wavelength light that still has sufficient energy to degrade wood. In this paper we test this hypothesis and determine the wavelengths of visible light that extend photodegradation into wood beyond the zone affected by UV radiation. Sugi (Cryptomeria japonica) earlywood was exposed to UV and visible light with narrow band gaps (20 nm) and the penetration of light into the wood was measured using a photodetector. Photodegradation was depth-profiled using FT-IR microscopy. There was a positive correlation between the penetration of light into sugi earlywood and the wavelength of the incident radiation within the range 246–496 nm. The depth of photodegradation also increased with wavelength up to and including the violet region (403 nm) of the visible spectrum. Blue light (434–496 nm) penetrated wood to a greater extent than violet light and was capable of bleaching the wood, but it did not significantly modify lignin, and hence it was not responsible for sub-surface photodegradation of wood. We conclude that violet light is the component of the visible spectrum that extends photodegradation into wood beyond the zone affected by UV radiation. Accordingly, surface treatments designed to protect wood used outdoors should shield wood from the effects of violet light.
Iterative target detection approach for Through-the-wall Radar Imaging

We consider the problem of target detection in Through-the-wall Radar Imaging when no a priori knowledge about the image statistics is available. An iterative approach which adapts itself to the unknown image statistics and thus allows for automatic target detection is presented. Two variants, based on 2D median filtering and morphological operations, are described in details. The proposed detection schemes are tested using experimental data, considering the problem of 3D reconstruction of a scene hidden behind a concrete wall.
Sensitivity of Grapevine Phenology to Water Availability, Temperature and CO2 Concentration

In recent decades, mean global temperatures have increased in parallel with a sharp rise in atmospheric carbon dioxide (CO2) levels, with apparent implications for precipitation patterns. The aim of the present work is to assess the sensitivity of different phenological stages of grapevine to temperature and to study the influence of other factors related to climate change (water availability and CO2 concentration) on this relationship. Grapevine phenological records from 9 plantings between 42.75°N and 46.03°N consisting of dates for budburst, flowering and fruit maturity were used. In addition, we used phenological data collected from two years of experiments with grapevine fruit-bearing cuttings with two grapevine varieties under two levels of water availability, two temperature regimes and two levels of CO2. Dormancy breaking and flowering were strongly dependent on spring temperature, while neither variation in temperature during the chilling period nor precipitation significantly affected budburst date. The time needed to reach fruit maturity diminished with increasing temperature and decreasing precipitation. Experiments under semi-controlled conditions revealed great sensitivity of berry development to both temperature and CO2. Water availability had significant interactions with both temperature and CO2; however, in general, water deficit delayed maturity when combined with other factors. Sensitivities to temperature and CO2 varied widely, but higher sensitivities appeared in the coolest year, particularly for the late ripening variety, ‘White Tempranillo’. The knowledge gained in whole plant physiology and multi stress approaches is crucial to predict the effects of climate change and to design mitigation and adaptation strategies allowing viticulture to cope with climate change.
Ontogeny of air-motion sensing in cricket

SUMMARY Juvenile crickets suffer high rates of mortality by natural predators that they can detect using extremely sensitive air-sensing filiform hairs located on their cerci. Although a huge amount of knowledge has accumulated on the physiology, the neurobiology and the biomechanics of this sensory system in adults, the morphological and functional aspects of air sensing have not been as well studied in earlier life history stages. Using scanning electronic microscopy, we performed a survey of all cercal filiform hairs in seven instars of the wood cricket (Nemobius sylvestris). Statistical analyses allowed us to quantify profound changes in the number, the length and the distribution of cercal hairs during development. Of particular importance, we found a fivefold increase in hair number and the development of a bimodal length-frequency distribution of cercal hairs from the second instar onwards. Based on theoretical estimations of filiform hair population coding, we found that the cercal system is functional for a wide range of frequencies of biologically relevant oscillatory flows, even from the first instar. As the cricket develops, the overall sensitivity of the cercal system increases as a result of the appearance of new hairs, but the value of the best tuned frequency remains fixed between 150 and 180 Hz after the second instar. These frequencies nicely match those emitted by natural flying predators, suggesting that the development of the cercal array of hairs may have evolved in response to such signals.
The Dynamic Range for Gain Control of NMDA Receptor-Mediated Synaptic Transmission at a Single Synapse

Although the level at which NMDA receptors (NMDARs) are activated can profoundly influence the direction and extent of long-term changes in synaptic strength, the probabilistic nature of quantal release at individual synapses makes it difficult to determine the dynamic operating range of NMDAR-mediated synaptic transmission. By continually driving glutamate release from a single high-fidelity auditory synapse with bursts of high-frequency stimuli, I show here that NMDAR-mediated EPSCs exhibited incremental summation in their amplitude and did not reach a plateau until six or seven consecutive stimuli into the train. An increase in the initial quantal output, by broadening presynaptic spikes with the potassium channel blocker tetraethylammonium (TEA, 0.2 mm), slightly increased the plateau amplitude at 200/300 Hz but shifted its peak temporally toward the earlier stimuli. These results suggest that the plateau amplitude in TEA reflects the activation of the entire population of synaptic NMDARs and hence the maximal gain of NMDAR-mediated synaptic transmission. This maximum was estimated to be 3.2-fold of the basal synaptic strength, giving a 31% occupancy of synaptic NMDARs by glutamate. Thus, synaptic NMDARs possess a broad dynamic range within which the activity-dependent control of synaptic strength and plasticity can potentially be tuned by the amount of Ca(2+) influx associated with different levels of NMDAR occupancy within the same synapse.