Miracle-dz/UniFAR-FTUs huggingface dataset:
Reduced spontaneous baroreflex response slope during lower body negative pressure after 28 days of head-down bed rest.

Effects of 28 days of continuous 6 degrees head-down tilt bed rest on spontaneous vagally mediated baroreflex response slope were evaluated from beat-by-beat relationships between R-R interval and systolic arterial blood pressure. Twelve healthy men (age 27-42 yr) were assigned to either countermeasure (CM) or no-countermeasure (no-CM) groups. CM consisted of strenuous short-term exercise once per day 6 days/wk from days 7 to 28 and lower body negative pressure (LBNP) for 15 min on days 16, 18, 20, and 22-28. Spontaneous baroreflex slope was evaluated by application of linear regression to sequences of at least three beats in which systolic blood pressure and R-R interval changed in the same direction. Measurements were made pre-, mid- (day 15), and post-bed rest at rest and during progressive LBNP tests (3 min at each of -20, -30, -40, and -50 mmHg). R-R interval decreased progressively and significantly (P < 0.0001) over duration of bed rest. Spontaneous baroreflex slope at rest in pre-bed rest was 18.5 +/- 2.1 ms/mm Hg for CM and 14.9 +/- 1.6 ms/mmHg for no-CM. There was a significant reduction in baroreflex slope as a function of bed rest, and it was further reduced during LBNP (P < 0.0001). Between CM and no-CM groups differences existed, but these were present pre-bed rest and appeared unaffected by countermeasures. (ABSTRACT TRUNCATED AT 250 WORDS)
Dynamically Downscaled Projections of Lake-Effect Snow in the Great Lakes Basin*,+

AbstractProjected changes in lake-effect snowfall by the mid- and late twenty-first century are explored for the Laurentian Great Lakes basin. Simulations from two state-of-the-art global climate models within phase 5 of the Coupled Model Intercomparison Project (CMIP5) are dynamically downscaled according to the representative concentration pathway 8.5 (RCP8.5). The downscaling is performed using the Abdus Salam International Centre for Theoretical Physics (ICTP) Regional Climate Model version 4 (RegCM4) with 25-km grid spacing, interactively coupled to a one-dimensional lake model. Both downscaled models produce atmospheric warming and increased cold-season precipitation. The Great Lakes’ ice cover is projected to dramatically decline and, by the end of the century, become confined to the northern shallow lakeshores during mid-to-late winter. Projected reductions in ice cover and greater dynamically induced wind fetch lead to enhanced lake evaporation and resulting total lake-effect precipitation, altho.
Structure and Composition of a Small Particle Prepared from a Simian Adenovirus

Mayor, Heather D. (Baylor University College of Medicine, Houston, Tex.), Richard M. Jamison, Liane E. Jordan, and Joseph L. Melnick. Structure and composition of a small particle prepared from a simian adenovirus. J. Bacteriol. 90:235–242. 1965. —When tissue-culture fluids infected with simian adenovirus SV15 are examined in an electron microscope, either as fresh harvests or after treatment with Genetron, typical mature adenovirus particles are found. These are 65 to 70 mμ in diameter, with an icosahedral capsid built from 252 capsomeres. Also present is a population of small polyhedral particles approximately 20 mμ in diameter. These small particles can be separated from the mature virions by ultrafiltration or density gradient centrifugation. The small particles have a density of 1.43 in cesium chloride. They contain protein and double-stranded deoxyribonucleic acid. They appear to possess cubic symmetry of the icosahedral type, with a coat composed of 12 subunits each at the vertex of an icosahedron.
Security Weakness of Flexible Group Key Exchange with On-Demand Computation of Subgroup Keys

In AFRICACRYPT 2010, Abdalla et al. first proposed a slight modification to the computations steps of the BD protocol, called mBD+P. Then they extended mBD+P protocol into mBD+S protocol. In this paper, we show that both of mBD+P and mBD+S protocols are vulnerable to malicious insiders attack. Further, we propose a simple countermeasure against this attack.
Substrate Effects on Pupation and Adult Emergence of Hermetia illucens (Diptera: Stratiomyidae)

ABSTBACT Black soldier flies, Hermetia illucens (L.) (Diptera: Stratiomyidae), are of particular interest for their applications in waste management. Feeding on decaying organic waste, black soldier flies successfully reduce manure in confined animal feeding operations of poultry, swine, and cattle. To optimize waste conversion in confined animal feeding operations and landfill facilities, it is imperative to optimize black soldier fly development. Unfortunately, black soldier flies only convert waste during their larval feeding stages and therefore it is of interest to optimize the nonfeeding stages of development, specifically, the postfeeding and pupal stages. The time spent in these stages is thought to be determined by the pupation substrate encountered by the postfeeding larvae. The objective of this study was to determine the effect different pupation substrates have on postfeeding development time, pupation time, and adult emergence success. Five pupation substrates were compared: wood shavings, potting soil, topsoil, sand, and nothing. Postfeeding larvae took longer to reach pupation in the absence of a pupation substrate, although reaching pupation in the shortest time in potting soil and wood shavings. The time spent in the pupal stage was shortest in the absence of a pupation substrate. However, fewer adults emerged when a pupation substrate was not provided.
A multi-view extension of the ICP algorithm

Although the Iterative Closest Point (ICP) algorithm has been an extremely popular method for 3D points or surface registration, it can only be applied to two point sets at a time. By only registering two scans at a time, ICP fails to exploit the redundant information available in multiple scans that have overlapping regions. In this paper, we present a multi-view extension of the ICP algorithm by a method that simultaneously averages the redundant information available in the scans with overlapping regions. Variants of this method that carry out such simultaneous registration in a causal manner and that utilise the transitive property of point correspondences are also presented. The improved accuracy of this motion averaged approach in comparison with ICP and some multi-view methods is established through multiple tests. We also present results of our method applied to some well-known real datasets.
Pan-African Granite Intrusion in Response to Tectonic Volume Changes in a Ductile Shear Zone from Northern Saudi Arabia

The Ajjaj shear zone of the Njad fault system of northwestern Saudi Arabia was a conduit for Pan-African (500-700 m.y.) calc-alkalic and peralkalic magmas. Ductility contrasts between the wall rocks and the deformed rocks of the shear zone were responsible for differences in size, intrusion mechanism, and degree of deformation of the granites. A quantitative strain analysis across the Ajjaj shear zone reveals a finite oblique strike-slip displacement of $$60 \pm 20 km$$ with a vertical displacement component of $$5 \pm 1.5 km$$. Granite diapirs were intruded within the region of volume gain; between 83-90% of the volume of the Ash Sha'b diapir was produced by expansion of the granite. Changes in late Pan-African granite magmatism, especially abrupt variations in alkalic granite distribution, can be indirectly linked with the vertical displacement components of the crustal blocks flanking the Ajjaj shear belt.
Embodying nation in food consumption : changing boundaries of "Taiwanese cuisine" (1895-2008)

This dissertation examines the transformations of “Taiwanese cuisine” under three different political regimes. In the Japanese colonial era, “Taiwanese cuisine” emerged as food for the elite and as the “food of the colony. ” However, the arrival of the Nationalist government and migrants from mainland China transplanted a condensed Chinese culinary map to Taiwan, while Taiwanese cuisine became a regional cuisine which was placed at a much lower level in the culinary hierarchy. After the establishment of the Democratic Progressive Party government in 2000, Taiwanese cuisine was imbued with symbolic meanings and began to be viewed as a “distinctive national cuisine. ” The exploration of Taiwanese cuisine shows that “national cuisine” is a relational and performative concept, as well as a commercial product. Nationhood, in the context of food, can render itself perceivable only to those who perceive the symbolic meanings of cuisine or those who embed meanings in particular dishes. It thus suggests that there are three stages leading to the embodiment of nationhood in food consumption and which together form a circle. First, specific cuisines are symbolized and performed as “national. ” Second, the symbolized cuisines are commodified. Finally, only when consumers perceive and practice these cuisines as national, nationhood can be embodied in these particular cuisines.
Small Mammal Inventories in the East and West Usambara Mountains, Tanzania. 4. Rodentia

Abstract During three field seasons between 1991 and 1993, we carried out rodent inventories of the East and West Usambara Mountains, Tanzania. The general trapping protocol used involved both pitfall lines and trap lines (Sherman, Victor, and Museum Special traps), with a limited number of animals trapped within and outside of forest habitats by local people. A total of 885 individual rodents, representing 15 species, were collected during this study. For the East and West Usambara Mountains, 13 (12 native) and 12 (all native) rodent species were recorded, respectively. Most rodents were captured by trap lines (96.6%); a few individuals were captured in the pitfall devices or brought to us by local people. The major exception is that all individuals of Dendromus (n = 11) obtained during the survey were in pitfall buckets. A total of 18,563 sample-nights were accrued over the three years, including 11,339 sample-nights (3314 pitfall-nights and 8025 trap-nights) in the East Usambara and 7224 sample-nights (1924 pitfall-nights and 5300 trap-nights) in the West Usambara Mountains. Based on species accumulation curves, no previously unrecorded species was trapped after 11,064 sample-nights in the East Usambara and after 5213 sample-nights in the West Usambara. However, a previously untrapped rodent (Graphiurus kelleni) was captured in the East Usambara on the third-to-last of 59 sampling days, suggesting that other non-canopy–restricted rodent species may have been missed during this survey. In a series of species accounts, information regarding the natural history of the different taxa handled during these surveys, including distribution, ecology, and condition of sexual organs, a list of referable specimens, and the trap devices that collected them, are presented. Trap and bucket lines combine to effectively sample most small- to medium-sized rodents. However, larger scansorial and canopy-restricted (squirrel) and fossorial (mole rat) species were not captured with our trapping methods, and these tabulations should not be considered a complete list of the small mammals of the Usambaras.
Average consensus with packet drop communication

The average consensus consists in determining the average of a number of quantities by means of a distributed algorithm. This is a simple instance of the problems which need to be faced when developing algorithms for the estimation of quantities from measures produced by sensor networks. Simple solutions based on linear estimators has already been proposed in the literature and their performance has been analyzed in detail. In this contribution the performance decay caused by data exchange through failing links is evaluated. In the model of the link proposed here at every time instant there is a certain probability that the data transmitted is lost by the link
Performance Evaluation of Dynamic Networks using an Evolving Graph Combinatorial Model

The highly dynamic behavior of wireless networks make them very difficult to evaluate, e.g. as far as the performance of routing algorithms is concerned. However, some of these networks, such as intermittent wireless sensors networks, periodic or cyclic networks, and low Earth orbit (LEO) satellites systems have more predictable dynamics, as the temporal variations in the network topology are somehow deterministic. Recently, a graph theoretic model-the evolving graphs-was proposed to help capture the dynamic behavior of these networks, in view of the construction of least cost routing and other algorithms. The algorithms and insights obtained through this model are theoretically very efficient and intriguing. However, there is no study on the uses of these theoretical results into practical situations. Therefore, the objective of this work is to analyze the applicability of the evolving graph theory in the construction of efficient routing protocols in realistic scenarios. In this paper, we used the NS2 network simulator to first implement an evolving graph based routing protocol, and then to evaluate such protocol compared to three major ad-hoc protocols (DSDV, DSR, AODV). Interestingly, our experiments showed that evolving graphs have all the potentials to be an effective and powerful tool in the development of algorithms for dynamic networks, with predictable dynamics at least. In order to make this model widely applicable, however, some practical issues still have to be addressed and incorporated into the model, like stochastically predictable behavior. We also discuss such issues in this paper, as a result of our experience
Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.

PURPOSE Patients with relapsed or refractory acute myeloid leukemia have a poor prognosis. We tested the safety and efficacy of a diphtheria fusion protein [diphtheria toxin (DT)388 granulocyte-macrophage colony-stimulating factor (GMCSF)] directed against the GMCSF receptor that is strongly expressed by leukemic blasts. EXPERIMENTAL DESIGN DT388GMCSF fusion protein containing the catalytic and translocation domains of DT388 fused to human GMCSF was administered in an interpatient dose escalation trial by 15 min i.v. infusion daily for up to 5 days. RESULTS The maximal tolerated dose was 4 microg/kg/day. The dose-limiting toxicity was liver injury and occurred at the 4.5-5-microg/kg/day dose level. Among nine treated patients at these doses, one patient developed liver failure, and one patient had transient hepatic encephalopathy. There was a positive correlation between peak serum DT388GMCSF levels and serum aspartate aminotransferase (P = 0.0002). DT388GMCSF did not damage hepatic cell lines in vitro; however, DT388GMCSF binds macrophages and induces cytokine release in vitro. Among the treated patients, we observed an early elevation in serum levels of interleukin (IL)-18 and a later rise in IL-8 but no significant changes in IL-1beta, IL-6, IFNgamma, macrophage inflammatory protein-1alpha, tumor necrosis factor alpha or IL-12. The IL-18 elevations occurred before elevations of liver enzymes and correlated with peak aspartate aminotransferase levels (P = 0.005). Of the 31 patients who were resistant to chemotherapy, 1 had a complete remission and 2 had partial remissions; all 3 of these patients were treated at or above the maximal tolerated dose, all 3 responding patients had baseline marrow blast percentage of <30%, whereas only 6 of the nonresponding 28 patients had less than 30% marrow blasts. Five of these six patients were treated with subtherapeutic doses. Eight (42%) of 19 patient courses at <4 microg/kg/day and 8 (40%) of 20 patient courses at 4-5 microg/kg/day showed marrow blast reductions at day 12. Patients with higher pretreatment anti-DT388GMCSF levels had significantly lower peak DT388GMCSF levels (P = 0.0001). CONCLUSIONS DT388GMCSF can produce complete and partial remissions in patients with chemotherapy-resistant acute myeloid leukemia, but methods to prevent liver injury are needed before more widespread application of this novel agent.
Ordovician to Silurian magmatism on the Utsira High, North Sea: implications for correlations between the onshore and offshore Caledonides

Abstract The age and tectonic significance of two basement granitoids cored on the Utsira High, Viking Graben, North Sea, are constrained by zircon LA-ICPMS data. Syenite in well 25/10-2R is dated to 482±2 Ma, with ϵHf(482) values from −4.4 to −5.8, and granite in well 16/1-12 yields an age of 436±3 Ma with ϵHf(436) values from +3.7 to −0.5. The evolved Hf-signature of the syenite demonstrates 482 Ma reworking of Palaeoproterozoic–Archaean crust, interpreted to reflect Taconian–Grampian orogenesis. New and recently published data from the offshore Caledonides allow a first-order correlation of the Utsira High basement with the surrounding on- and offshore Caledonides. The Utsira High occupies a similar position with respect to Dalradian rocks as the Scottish Midland Valley terrane. Geophysical data indicate a volcanic arc beneath the East Shetland Basin, forming a northwards continuation of the Utsira High basement. We propose that the offshore volcanic arc segments represent the northeastern continuation of the Scottish Grampian orogen across the Mesozoic North Sea rift. A north-striking terrane boundary fault is proposed to separate the volcanic arc from the East Shetland Platform and merge northwards with the offshore extension of the Great Glen Fault–Møre Trøndelag Fault Complex. Supplementary material: U–Pb and Lu–Hf isotopic data are available at http://www.geolsoc. org.uk/SUP18705.
A note on the textural variation of beach sediments in the vicinity of Gangavali river mouth near Ankola, West Coast of India

Sediment samples collected from beaches in the vicinity of Gangavali river mouth over a period of 18 months between September 1985 and February 1987 revealed that the sediments are coarse to fine grained (0.27-2.67 theta), moderate to well sorted (0.03-0.97 theta), coarse (-ve) to fine (+ve) skewed and mesokurtic. The observed variations in textural parameters are both spatial and time dependent and gives signatures of changes in oceanographic conditions.
Time-averaged current analysis of a thunderstorm using ground-based measurements

The amount of upward current provided to the ionosphere by a thunderstorm that appeared over the Kennedy Space Center (KSC) on July 11, 1978, is reexamined using an analytic equation that describes a bipolar thunderstorm's current contribution to the global circuit in terms of its generator current, lightning currents, the altitudes of its charge centers, and the conductivity profile of the atmosphere. Ground-based measurements, which were obtained from a network of electric field mills positioned at various distances from the thunderstorm, were used to characterize the electrical activity inside the thundercloud. The location of the lightning discharges, the type of lightning, and the amount of charge neutralized during this thunderstorm were computed through a least squares inversion of the measured changes in the electric fields following each lightning discharge. These measurements provided the information necessary to implement the analytic equation, and consequently, a time-averaged estimate of this thunderstorm's current contribution to the global circuit was calculated. From these results the amount of conduction current supplied to the ionosphere by this small thunderstorm was computed to be less than 25% of the time-averaged generator current that flowed between the two vertically displaced charge centers.
Isolated Rat Liver Needs Calcium to Make Bile

Summary When normal rat livers were perfused with heparinized normal rat whole blood by the Brauer et al. technique, between 10 and 15 μl of bile were excreted per minute. This amount was drastically reduced by the addition of sodium citrate to the blood. When calcium chloride was subsequently added, bile flow returned to normal if the interval between the additions of citrate and calcium was not over an hour. Magnesium chloride had no such corrective effect. Two tests of liver function, generation of factor VII and conversion of [14C]alanine to TCA-precipitable 14C, were unaffected by the addition of citrate to plasma-free perfusions.
Natural Remanent Magnetization and Viscous Magnetization of Apollo 11 Lunar Materials

The natural remanent magnetization (NRM) of three Apollo 11 lunar materials, i. e. a crystalline rock and two kinds of microbreccia, is examined in detail with special attention to the possible effect of viscous magnetization acquirable in the terrestrial magnetic field.The intensity of stable NRM (In), the critical AC-demagnetization field (H*) which represents the upper limit for keeping approximate invariance of NRM direction, and the effective demagnetization field (H0) which reduces the intesity of NRM to (1/e) of the initial value are determined as follows; (a) In=8.9×10-6emu/gm, H*=30Oe, H0=25Oe for a crystalline rock (NASA No. 10024.22): (b) In=1.50×10-5emu/gm, H*=40Oe, H0=35Oe for a weakly impacted microbreccia (No. 10021.32): (c) In=1.50×10-4emu/gm H*>500Oe, H0≅1400Oe for a strongly impacted microbreccia (No. 10085·16). The intense and extremely stable NRM of the strongly impacted lunar microbreccia may suggest that a strong impact of lunar materials can cause an acquisition of a particularly stable remanent magnetization even in a very weak magnetic field.A certain portion of metallic irons in the lunar materials are very fine particles of several hundreds of Angstrom in mean diameter. These particles behave almost superpara-magnetically. Saturated viscous remanent magnetization acquired in the geomagnetic field being denoted by ΔIv, the ratio of 44 to the stable remanence In is determined to be 0.015, 8.4 and 0.23 respectively in cases of (a), (b) and (c). The larger value of the ratio ΔIv/In indicates that the larger portion of fine particles of metallic irons. The relaxation time of the viscous magnetization at 20°C ranges from 2×10 to 7×104sec. , which implies that the grain size of the find iron particles is 170-180A in diameter.
Abnormal treating pressures in MHF treatments

Abnormal treating pressures are observed during massive hydraulic fracturing (MHF) treatments in the Mesa Verde formation of the Piceance Basin, Colorado. Data from three widely separated wells and in several zones per well all show a pressure increase during MHF treatments which the authors call ''pressure growth''. This pressure growth is at least semi-permanent. The elevated instantaneous shut-in pressures do not return to initial values over periods of several days. The magnitude of this pressure growth is highly variable. When its value is less than about 2300 psi the MHF treatments are usually completed and results are obtained which are within normal expectations. When its value exceeds 2300 psi, sandout occurs and the fracture length estimated from production data is much less than that calculated using crack propagation models. Temperature logs indicate little or only modest vertical extension of the fractures above the perforations. These data, along with sandouts, point to a large increase in width of the fractures in response to pressure growth. One possible cause of pressure growth is fracture branching. A multiplicity of branches could produce a plastic-like effect. Laboratory measurements have ruled out plasticity as the cause. The stress-strain behavior of the rock is similar tomore » that of rocks where no pressure growth occurs. Pressure growth seems to be dependent on both pumping rate and fluid viscosity. Thus, there is some hope for its mitigation through treatment design. Also, pressure growth appears to correlate negatively with pay zone quality. This suggests that the phenomenon can be exploited as a fluid diversion technique. « less