Miracle-dz/UniFAR-FTUs huggingface dataset:
Measurement of Giant Spin Splitting of Reflected Gaussian Beams

We investigate theoretically and experimentally the beam shifts of a Gaussian beam reflected by an air-glass interface at Brewster incidence. For a linearly polarized incident beam, the reflected beam will undergo a spatial spin splitting within the plane of incidence. This spin splitting is up to 83 μm when the incident beam waist is 90 μm. Additionally, the reflected beam will be deflected along the direction perpendicular to the incident plane, i.e., undergo an angular shift. The maximum angular shift has been theoretically predicted and experimentally confirmed. Both the spatial spin splitting and angular shift can be controlled by the incident polarization state. These controllable giant beam shifts have potential applications in the design of spin-photonic devices and the optical sensing.
Bleeding Risk during Treatment of Acute Thrombotic Events with Subcutaneous LMWH Compared to Intravenous Unfractionated Heparin; A Systematic Review

Background Low Molecular Weight Heparins (LMWH) are at least as effective antithrombotic drugs as Unfractionated Heparin (UFH). However, it is still unclear whether the safety profiles of LMWH and UFH differ. We performed a systematic review to compare the bleeding risk of fixed dose subcutaneous LMWH and adjusted dose UFH for treatment of venous thromboembolism (VTE) or acute coronary syndromes (ACS). Major bleeding was the primary end point. Methods Electronic databases (MEDLINE, EMBASE, and the Cochrane Library) were searched up to May 2010 with no language restrictions. Randomized controlled trials in which subcutaneous LMWH were compared to intravenous UFH for the treatment of acute thrombotic events were selected. Two reviewers independently screened studies and extracted data on study design, study quality, incidence of major bleeding, patients’ characteristics, type, dose and number of daily administrations of LMWH, co-treatments, study end points and efficacy outcome. Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using the random effects model. Results Twenty-seven studies were included. A total of 14,002 patients received UFH and 14,635 patients LMWH. Overall, no difference in major bleeding was observed between LMWH patients and UFH (OR = 0.79, 95% CI 0.60–1.04). In patients with VTE LMWH appeared safer than UFH, (OR = 0.68, 95% CI 0.47–1.00). Conclusion The results of our systematic review suggest that the use of LMWH in the treatment of VTE might be associated with a reduction in major bleeding compared with UFH. The choice of which heparin to use to minimize bleeding risk must be based on the single patient, taking into account the bleeding profile of different heparins in different settings.
Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

Objective Rheumatoid arthritis (RA) is a chronic and progressive joint disease. It appears that anti-inflammatory feedback mechanisms that could restrain joint inflammation and restore homeostasis are insufficient to perform this control. In this study, we investigated the contribution of the MER tyrosine kinase-mediated anti-inflammatory response on arthritis and whether targeting MER could be a valid approach to treat RA. Methods KRN serum transfer arthritis (KRN STA) was induced in either Mertk-deficient mice or in mice that adenovirally overexpressed Pros1. Human synovial micromasses were treated with MER-specific antibodies or PROS1. Collagen-induced arthritis (CIA) mice were treated with MER-specific agonistic antibodies or by viral overexpression of Pros1. Results Mertk−/− mice showed exacerbated arthritis pathology, whereas Pros1 overexpression diminished joint pathology in KRN STA. Human synovial micromasses challenged with MER-specific antibodies enhanced the secretion of inflammatory cytokines, whereas stimulating MER with PROS1 reduced the secretion of these cytokines, confirming the protective role of MER. Next, we treated CIA mice with MER-specific agonistic antibodies, and this unexpectedly resulted in exacerbated arthritis pathology. This was associated with increased numbers of apoptotic cells in their knee joints and higher serum levels of interleukin (IL)-16C, a cytokine released by secondary necrotic neutrophils. Apoptotic cell numbers and IL-16C levels were enhanced during arthritis in Mertk−/− mice and reduced in Pros1-overexpressing mice. Conclusion MER plays a protective role during joint inflammation and activating MER by its ligand PROS1 ameliorates disease. Treatment of mice with MER receptor agonistic antibodies is deleterious due to its counterproductive effect of blocking efferocytosis in the arthritic joint.
Design of Polar Codes in 5G New Radio

Polar codes have attracted the attention of academia and industry alike in the past decade, such that the <inline-formula> <tex-math notation="LaTeX">$5^{\mathrm {th}}$ </tex-math></inline-formula> generation wireless systems (5G) standardization process of the <inline-formula> <tex-math notation="LaTeX">$3^{\mathrm {rd}}$ </tex-math></inline-formula> generation partnership project (3GPP) chose polar codes as a channel coding scheme. In this tutorial, we provide a description of the encoding process of polar codes adopted by the 5G standard. We illustrate the struggles of designing a family of polar codes able to satisfy the demands of 5G systems, with particular attention to rate flexibility and low decoding latency. The result of these efforts is an elaborate framework that applies novel coding techniques to provide a solid channel code for NR requirements.
From kitchen to classroom: Assessing the impact of cleaner burning biomass-fuelled cookstoves on primary school attendance in Karonga district, northern Malawi

Household air pollution from burning solid fuels is responsible for an estimated 2.9 million premature deaths worldwide each year and 4.5% of global disability-adjusted life years, while cooking and fuel collection pose a considerable time burden, particularly for women and children. Cleaner burning biomass-fuelled cookstoves have the potential to lower exposure to household air pollution as well as reduce fuelwood demand by increasing the combustion efficiency of cooking fires, which may in turn yield ancillary benefits in other domains. The present paper capitalises on opportunities offered by the Cooking and Pneumonia Study (CAPS), the largest randomised trial of biomass-fuelled cookstoves on health outcomes conducted to date, the design of which allows for the evaluation of additional outcomes at scale. This mixed methods study assesses the impact of cookstoves on primary school absenteeism in Karonga district, northern Malawi, in particular by conferring health and time and resource gains on young people aged 5–18. The analysis combines quantitative data from 6168 primary school students with in-depth interviews and focus group discussions carried out among 48 students in the same catchment area in 2016. Negative binomial regression models find no evidence that the cookstoves affected primary school absenteeism overall [IRR 0.92 (0.71–1.18), p = 0.51]. Qualitative analysis suggests that the cookstoves did not sufficiently improve household health to influence school attendance, while the time and resource burdens associated with cooking activities—although reduced in intervention households—were considered to be compatible with school attendance in both trial arms. More research is needed to assess whether the cookstoves influenced educational outcomes not captured by the attendance measure available, such as timely arrival to school or hours spent on homework.
Recognition Within the Decision-Making Process: A Case Study of Expert Volleyball Players

This article reports on decision-making under time pressure conditions. It aims at testing the Recognition-Primed Decision model with regard to volleyball. Seven male expert players participated in this study. A match was videotaped; each player was interviewed in a self-confrontation interview. Inductive and deductive analysis revealed three main results. The first showed that their decision-making was based on a recognition process of the situation typicality. The second emphasized that this process had four by-products: (a) expectations, (b) relevant cues, (c) plausible goals, and (d) typical action. The players did not equally report these by-products. The third main result showed that the decisions were largely prearranged. They consisted of an association between a typical situation and a typical action, the typical action was then adapted to the current situation. The results are discussed in relation to the Recognition-Primed Decision model and to research that has considered decision-making.
Mid-infrared frequency comb generation via cascaded quadratic nonlinearities in quasi-phase-matched waveguides.

We experimentally demonstrate a simple configuration for mid-infrared (MIR) frequency comb generation in quasi-phase-matched lithium niobate waveguides using the cascaded-χ(2) nonlinearity. With nanojoule-scale pulses from an Er:fiber laser, we observe octave-spanning supercontinuum in the near-infrared with dispersive wave generation in the 2.5-3 μm region and intrapulse difference frequency generation in the 4-5 μm region. By engineering the quasi-phase-matched grating profiles, tunable, narrowband MIR and broadband MIR spectra are both observed in this geometry. Finally, we perform numerical modeling using a nonlinear envelope equation, which shows good quantitative agreement with the experiment-and can be used to inform waveguide designs to tailor the MIR frequency combs. Our results identify a path to a simple single-branch approach to mid-infrared frequency comb generation in a compact platform using commercial Er:fiber technology.
Hobbes to Rousseau: Inequality, Institutions, and Development

We analyze the endogenous evolution of economic and political institutions and the interdependencies with the process of economic development. Favorable economic institutions ensure the appropriability of rents in form of a state of law. We study the conditions under which a state of law can be implemented under oligarchy, and when democratization is necessary. Inequality in endowments and incomes prolongs the absence of good institutions and delays democratization. Conversely, institutions shape the income distribution. Simulations illustrate how inequality affects the development process and may lead to overtaking and divergence. The implications are in line with historical and empirical evidence.
Objective and subjective parameters of oral health in South Indian children: A cross-sectional study

Background: Oral health of schoolchildren is a strong predictor of their overall well-being. This study was planned to assess and compare the objective and subjective parameters of oral health of South Indian school children. Methodology: Three hundred and sixty school children participated in this cross-sectional study. Their oral hygiene status, dental caries status, and treatment needs were assessed. Two questionnaires were filled by these children, to assess their oral health-related quality of life (OHRQoL) and their knowledge on oral health. Their academic scores were collected from the schools. Statistical analysis was done using Kruskal–Wallis ANOVA test and Spearman correlation test appropriately. Results: Children with no caries had better OHRQoL (P = 0.02). There was a negative correlation between dental caries status and OHRQoL score (P = 0.003) and dental caries treatment needs and OHRQoL score (P = 0.01). There was a positive correlation between knowledge on oral health and OHRQoL score (P = 0.02). Conclusion: Children with no caries had a better OHRQoL when compared to children with caries. Children with caries had more treatment needs, poor oral hygiene, low quality of life, and performed lesser in academics. However, they had adequate knowledge on oral health. Hence, both objective and subjective parameters of oral health should be given importance while treating children.
Cannabis use and knowledge among medical students at the University of the Free State, Bloemfontein, South Africa

Objective: The study aimed to investigate the prevalence of cannabis use among undergraduate medical students of the University of the Free State (UFS), and the extent of their knowledge about the substance. Method: This cross-sectional study included five year groups of undergraduate medical students. A self-administered, anonymous questionnaire was used. Results: Of the 643 medical students, 541 (84.1%) completed the questionnaire. In total, 161 (30.9%) students reported that they had ever used cannabis. The percentage of males who had ever used cannabis was twice that of females (relative risk 2.04; 95% CI 1.56; 2.67). Of the cannabis users, less than 12% used it monthly or more often. A fifth (19.5%) of all students stated that they did not know the side effects of cannabis use. Nearly half (45.4%) indicated that they could not name any medicinal (medical) uses. The median knowledge score of students who used cannabis tended to be higher than that of students who did not use cannabis; this was statistically significant only in the third-year group. Conclusions: Medical students generally have a low level of knowledge about cannabis. The reported lifetime prevalence and pattern of cannabis use are similar to those reported in other South African studies published over the past 35 years.
Multiple-copy two-state discrimination with individual measurements

We address the problem of nonorthogonal two-state discrimination when multiple copies of the unknown state are available. We give the optimal strategy when only fixed individual measurements are allowed and show that its error probability saturates the collective slowerd bound asymptotically. We also give the optimal strategy when adaptivity of individual von Neumann measurements is allowed swhich requires classical communicationd and show that the corresponding error probability is exactly equal to the collective one for any number of copies. We show that this strategy can be regarded as Bayesian updating.
Oasis: Onboard autonomous science investigation system for opportunistic rover science

The Onboard Autonomous Science Investigation System has been developed to enable a rover to identify and react to serendipitous science opportunities. Using the FIDO rover in the Mars Yard at JPL, we have successfully demonstrated a fully autonomous opportunistic science system. The closed loop system tests included the rover acquiring image data, finding rocks in the image, analyzing rock properties and identifying rocks that merit further investigation. When the system on the rover alerts the rover to take additional measurements of interesting rocks, the planning and scheduling component determines if there are enough resources to meet this additional science data request. The rover is then instructed to either turn toward the rock, or to actually move closer to the rock to take an additional, close‐up image. Prototype dust devil and cloud detection algorithms were delivered to an infusion task which refined the algorithms specifically for Mars Exploration Rovers (MER). These algorithms have been integrated into the MER flight software and were recently uploaded to the rovers on Mars. © 2007 Wiley Periodicals, Inc.
Exploiting innocuous activity for correlating users across sites

We study how potential attackers can identify accounts on different social network sites that all belong to the same user, exploiting only innocuous activity that inherently comes with posted content. We examine three specific features on Yelp, Flickr, and Twitter: the geo-location attached to a user's posts, the timestamp of posts, and the user's writing style as captured by language models. We show that among these three features the location of posts is the most powerful feature to identify accounts that belong to the same user in different sites. When we combine all three features, the accuracy of identifying Twitter accounts that belong to a set of Flickr users is comparable to that of existing attacks that exploit usernames. Our attack can identify 37% more accounts than using usernames when we instead correlate Yelp and Twitter. Our results have significant privacy implications as they present a novel class of attacks that exploit users' tendency to assume that, if they maintain different personas with different names, the accounts cannot be linked together; whereas we show that the posts themselves can provide enough information to correlate the accounts.
Flow and distribution of reinforced particulates in A356/SiC_p vertical upwards suction casting

An A356/10%SiCp(100 μm) upward suction casting was conducted with stirring casting technique.The SiCp contents of different sections in the casting were quantitatively measured with micro digital image analysis system.Based on the Eulerian-Lagrangian method,a model for the particle reinforced-composite casting mold filling was presented.It was applied to the composite liquid flow and SiC particulate distribution in the experimental casting.The simulation results were compared and validated with the experimental ones.The results show that the SiC particulates are prone to be aggregated near the mold wall at the casting filling beginning part;they move towards the centre as the filling distance increases,resulting in slightly higher content of SiC particulate within the centre part in the casting front;the SiC particulate contents decrease along the upward mold filling direction.
Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma

Gliomas are the most common and aggressive type of primary adult brain tumors. Although TREM2 mutation is reported to be related to Nasu-Hakola disease and Alzheimer's disease, little is known about the association between TREM2 and gliomas. Here, we reported that TREM2 was significantly overexpressed in glioma tissues compared with non-tumorous brain tissues. Furthermore, TREM2 expression was closely related to pathological grade and overall survival of patients with gliomas. Down-regulation of TREM2 in two glioma cell lines, U87 and U373, resulted in a significant reduction in cell proliferation, migration and invasion and a dramatic increase in S phase arrest and apoptosis. In vivo tumorigenesis experiment also revealed that depletion of TREM2 expression inhibited U87 cell proliferation. Moreover, based on gene set enrichment analysis (GSEA) with The Cancer Genome Atlas (TCGA) dataset, we found that TREM2 was positive related to Kyoto Encyclopedia of Genes and Genomes (KEGG) apoptosis, Cromer metastasis and KEGG chemokine pathways, which was further validated by western blot in TREM2 knockdown glioma cells and indicated a possible mechanism underlying its effects on glioma. In summary, our study suggests that TREM2 may work as an oncogene and a new effective therapeutic target for glioma treatment.
Concerns about Quadrupole ICP-MS Lead Isotopic Data and Interpretations in the Environment and Health Fields

There has been a massive increase in recent years of the use of lead (Pb) isotopes in attempts to better understand sources and pathways of Pb in the environment and in man or experimental animals. Unfortunately, there have been many cases where the quality of the isotopic data, especially that obtained by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS), are questionable, resulting in questionable identification of potential sources, which, in turn, impacts study interpretation and conclusions. We present several cases where the isotopic data have compromised interpretation because of the use of only the major isotopes 208Pb/206Pb and 207Pb/206Pb, or their graphing in other combinations. We also present some examples comparing high precision data from thermal ionization (TIMS) or multi-collector plasma mass spectrometry (MC-ICP-MS) to illustrate the deficiency in the Q-ICP-MS data. In addition, we present cases where Pb isotopic ratios measured on Q-ICP-MS are virtually impossible for terrestrial samples. We also evaluate the Pb isotopic data for rat studies, which had concluded that Pb isotopic fractionation occurs between different organs and suggest that this notion of biological fractionation of Pb as an explanation for isotopic differences is not valid. Overall, the brief review of these case studies shows that Q-ICP-MS as commonly practiced is not a suitable technique for precise and accurate Pb isotopic analysis in the environment and health fields.
Analysis of Heavy Oil Recovery by Thermal EOR in a Meander Belt: From Geological to Reservoir Modeling

The objectives of this work is to assess the impact of reservoir heterogeneities on heavy oil recovery of a reservoir analogue of meander belt through the Steam Assisted Gravity Drainage (SAGD) process by using numerical models. These models are obtained with different scales of upscaling of the geological model. Meander belts consist of point bar deposits, characterized by a 3D complex internal architecture, with different scales of heterogeneities, which distribution is associated with the depositional processes. Based on a 3D outcrop description of a meander belt analogue to the Canadian heavy-oil fields, the approach includes three steps: 1) the construction of a reference static reservoir model based on a very fine description of the outcrops in terms of architecture and geological heterogeneities, 2) upscaling of the grid at different scales using different upscaling factors in order to evaluate their impact on the heterogeneity distribution in the reservoir, 3) reservoir SAGD simulations using horizontal well doublet (steam injector and producer) across the meander belt, so as to assess the impact of upscaling of heterogeneities on heavy oil production. The impact of heterogeneities on simulation results are evaluated for several upscaling stages. Results show that heterogeneity distribution has an impact on fluid flow at different stages of production. On the fine gridded model, small scale heterogeneities impact the steam chamber development and fluid flow in the wellbore vicinity at the beginning of the steam injection, whereas large scale heterogeneities strongly influence oil recovery during the whole recovery process and lower the efficiency of the reservoir drainage. On coarser grids, the effect of small-scale heterogeneities can be diminished, depending on the upscaling stage. The geomechanical effect is not taken into account in this work, the objective being to assess the impact of heterogeneities on oil recovery. The performance of SAGD is clearly linked to the steam chamber development, which depends on the degree of heterogeneities present in the reservoir. The simulation workflow and the sensitivity study on the upscaling method contribute to a better restoration of the heterogeneity distribution in the reservoir. The negative effect of these heterogeneities during the oil recovery must thus be quantified in order to monitor the thermal production at crucial periods of the production process.