Miracle-dz/UniFAR-FTUs huggingface dataset:
Dietary fat interacts with the -514C>T polymorphism in the hepatic lipase gene promoter on plasma lipid profiles in a multiethnic Asian population: the 1998 Singapore National Health Survey.

We have previously reported an interaction between -514C>T polymorphism at the hepatic lipase (HL) gene and dietary fat on high-density lipoprotein-cholesterol (HDL-C) metabolism in a representative sample of white subjects participating in the Framingham Heart Study. Replication of these findings in other populations will provide proof for the relevance and consistency of this marker as a tool for risk assessment and more personalized cardiovascular disease prevention. Therefore, we examined this gene-nutrient interaction in a representative sample of Singaporeans (1324 Chinese, 471 Malays and 375 Asian Indians) whose dietary fat intake was recorded by a validated questionnaire. When no stratification by fat intake was considered, the T allele was associated with higher plasma HDL-C concentrations (P = 0.001), higher triglyceride (TG) concentrations (P = 0.001) and higher HDL-C/TG ratios (P = 0.041). We found a highly significant interaction (P = 0.001) between polymorphism and fat intake in determining TG concentration and the HDL-C/TG ratio (P = 0.001) in the overall sample even after adjustment for potential confounders. Thus, TT subjects showed higher TG concentrations only when fat intake supplied >30% of total energy. This interaction was also found when fat intake was considered as continuous (P = 0.035). Moreover, in the upper tertile of fat intake, TT subjects had 45% more TG than CC individuals (P < 0.01). For HDL-C concentration, the gene-diet interaction was significant (P = 0.015) only in subjects of Indian origin. In conclusion, our results indicate that there are differences in the association of -514C>T polymorphism with plasma lipids according to dietary intake and ethnic background. Specifically, the TT genotype is associated with a more atherogenic lipid profile when subjects consume diets with a fat content > 30%.
Training Restricted Boltzmann Machines on Word Observations

The restricted Boltzmann machine (RBM) is a flexible model for complex data. However, using RBMs for high-dimensional multinomial observations poses significant computational difficulties. In natural language processing applications, words are naturally modeled by K-ary discrete distributions, where K is determined by the vocabulary size and can easily be in the hundred thousands. The conventional approach to training RBMs on word observations is limited because it requires sampling the states of K-way softmax visible units during block Gibbs updates, an operation that takes time linear in K. In this work, we address this issue with a more general class of Markov chain Monte Carlo operators on the visible units, yielding updates with computational complexity independent of K. We demonstrate the success of our approach by training RBMs on hundreds of millions of word n-grams using larger vocabularies than previously feasible with RBMs and by using the learned features to improve performance on chunking and sentiment classification tasks, achieving state-of-the-art results on the latter.
Postpartum iron status in nonlactating participants and nonparticipants in the special supplemental nutrition program for women, infants, and children.

BACKGROUND Iron deficiency, a pervasive problem among low-income women of childbearing age, threatens maternal health and pregnancy outcomes. The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) was designed to alleviate health problems and provides supplemental nutritious foods, nutrition education, and health care referrals. OBJECTIVES The aim of this study was to examine the benefits associated with participation in WIC in terms of biochemical tests of postpartum iron status in nonlactating women. DESIGN WIC participants (n = 57) and eligible nonparticipants (n = 53), matched by race and age, were followed bimonthly over 6 mo postpartum. Finger stick blood samples (500 microL) were collected for measurement of plasma ferritin, transferrin receptor (TfR), and hemoglobin (Hb). RESULTS The mean (+/-SE) Hb concentration of participants exceeded that of nonparticipants from months 2 through 6. At 6 mo, the mean Hb concentration of participants was significantly higher than that of nonparticipants (8.01+/-0.12 and 7.63+/-0.12 mmol/L, respectively; P< 0.05) and the prevalence of anemia was significantly lower (17% and 51%, respectively; P<0.05). TfR and ferritin concentrations (consistently within the reference ranges) and dietary iron intakes did not differ significantly between participants and nonparticipants and were not correlated with Hb concentrations. CONCLUSIONS Our results suggest that WIC participants were significantly less likely to become anemic if uninterrupted postpartum participation lasted for 6 mo. The lack of correlation among iron status indicators suggests that the lower mean Hb concentration in nonparticipants at 6 mo may not have been related to improved iron status in participants but to other nutrient deficiencies or differences in access to health care and health and nutrition education.
Using code ownership to improve IR-based Traceability Link Recovery

Information Retrieval (IR) techniques have gained wide-spread acceptance as a method for automating traceability recovery. These techniques recover links between software artifacts based on their textual similarity, i.e., the higher the similarity, the higher the likelihood that there is a link between the two artifacts. A common problem with all IR-based techniques is filtering out noise from the list of candidate links, in order to improve the recovery accuracy. Indeed, software artifacts may be related in many ways and the textual information captures only one aspect of their relationships. In this paper we propose to leverage code ownership information to capture relationships between source code artifacts for improving the recovery of traceability links between documentation and source code. Specifically, we extract the author of each source code component and for each author we identify the “context” she worked on. Thus, for a given query from the external documentation we compute the similarity between it and the context of the authors. When retrieving classes that relate to a specific query using a standard IR-based approach we reward all the classes developed by the authors having their context most similar to the query, by boosting their similarity to the query. The proposed approach, named TYRION (TraceabilitY link Recovery using Information retrieval and code OwNership), has been instantiated for the recovery of traceability links between use cases and Java classes of two software systems. The results indicate that code ownership information can be used to improve the accuracy of an IR-based traceability link recovery technique.
Exploring Staff Clinical Knowledge and Practice with LGBT Residents in Long-Term Care: A Grounded Theory of Cultural Competency and Training Needs

ABSTRACT Objectives: Existing literature shows that LGBT residents are likely to face suboptimal care in LTC facilities due to prejudice and discriminatory policies. The aim of this project was to assess the LGBT cultural competency of staff working in LTC facilities, identify their current training needs, and develop a framework for understanding LGBT cultural competency among LTC staff and providers. Methods: This grounded theory study comprised data from focus groups of interdisciplinary staff from three LTC facilities. Results: Results suggested that LTC staff struggle with how to be sensitive to LGBT residents’ needs. Tension appeared to exist between wanting to provide an equal standard of care to all LTC residents and fearing they would show “favoritism” or “special treatment,” which might be viewed as unprofessional. Participants indicated training could help to address the ambivalence they experience about providing sensitive care to subpopulations of residents who face stigma and oppression. Conclusions: LTC staff stand to benefit from cultural competency training focused on LGBT residents. Training should be not only informational in nature, but also facilitate greater self-awareness and self-efficacy with respect to providing care to LGBT people.
Biomass smoke from southern Africa can significantly enhance the brightness of stratocumulus over the southeastern Atlantic Ocean

Significance Each year biomass burning (BB) aerosols emitted in southern Africa during the fire season (July–October) transport westward over the southeast Atlantic Ocean and interact with underlying stratocumulus decks. Previous studies showed that BB aerosols greatly perturb the top of atmosphere radiation balance by scattering and absorbing solar radiation and by altering cloud properties via changing the lower tropospheric stability (direct and semidirect effects). Using a state-of-the-art model in combination with satellite observations, we found that BB aerosols that are entrained into the clouds function as cloud condensation nuclei, and increase the brightness of stratocumulus clouds (indirect effect). In these models, this indirect effect dominates the direct and semidirect effects of BB aerosols over this region. Marine stratocumulus clouds cover nearly one-quarter of the ocean surface and thus play an extremely important role in determining the global radiative balance. The semipermanent marine stratocumulus deck over the southeastern Atlantic Ocean is of particular interest, because of its interactions with seasonal biomass burning aerosols that are emitted in southern Africa. Understanding the impacts of biomass burning aerosols on stratocumulus clouds and the implications for regional and global radiative balance is still very limited. Previous studies have focused on assessing the magnitude of the warming caused by solar scattering and absorption by biomass burning aerosols over stratocumulus (the direct radiative effect) or cloud adjustments to the direct radiative effect (the semidirect effect). Here, using a nested modeling approach in conjunction with observations from multiple satellites, we demonstrate that cloud condensation nuclei activated from biomass burning aerosols entrained into the stratocumulus (the microphysical effect) can play a dominant role in determining the total radiative forcing at the top of the atmosphere, compared with their direct and semidirect radiative effects. Biomass burning aerosols over the region and period with heavy loadings can cause a substantial cooling (daily mean −8.05 W m−2), primarily as a result of clouds brightening by reducing the cloud droplet size (the Twomey effect) and secondarily through modulating the diurnal cycle of cloud liquid water path and coverage (the cloud lifetime effect). Our results highlight the importance of realistically representing the interactions of stratocumulus with biomass burning aerosols in global climate models in this region.
Multiple Identification Foci and Their Countervailing Effects on Salespeople's Negative Headquarters Stereotypes

Using a large-scale, multilevel data set, this study introduces to the sales management literature the concept of sales representatives' headquarters stereotypes as a negative outcome of social identification. The results suggest that work team identification fosters headquarters stereotyping more strongly when organizational identification is low than when it is high. Salespeople's physical distance from their corporate headquarters increases work team identification and decreases organizational identification. Competitive intensity, as an external threat to salespeople's social identity, strengthens stereotyping and social identification. In addition to important theoretical implications, this research also provides crucial insights for managers. Headquarters stereotypes are critically important because they can have harmful consequences for sales performance and customer satisfaction. Key managerial implications are that managers should foster organizational identification and that using different compensation systems does not remedy the negative effects of stereotypes.
Team Entitativity and Teacher Teams in Schools: Towards a Typology.

In this article we summarise research that discusses „teacher teams‟. The central questions guiding this study are „How is the term „teacher team‟ used and defined in previous research? ‟ and „What types of teacher teams has previous research identified or explored? ‟. We attempted to answer these questions by searching literature on teacher teams and comparing what these articles present as being teacher teams. We attempted to further grasp the concept of teacher teams by creating a typology for defining different types of teacher teams. Overall, the literature pertaining to teacher teams appeared to be characterised by a considerable amount of haziness and teacher „teams‟ mostly do not seem to be proper „teams‟ when keeping the criteria of a team as defined by Cohen and Bailey (1997) in mind. The proposed typology, characterising the groups of teachers by their task, whether they are organised disciplinary or interdisciplinary, whether they are situated within or cross grades, their temporal duration and degree of team entitativity or „teamness‟, appears to be a useful framework to further clarify different sorts of teacher „teams‟.
Endoscopic versus percutaneous management for symptomatic pancreatic fluid collections: a systematic review and meta-analysis

Abstract Background Symptomatic pancreatic fluid collections (PFCs) are managed by surgical, percutaneous, or endoscopic drainage. Due to morbidity associated with surgical drainage, percutaneous and/or endoscopic options have increasingly been used as initial management. Aims We conducted a systematic review and meta-analysis comparing the efficacy and safety of endoscopic versus percutaneous drainage for management of PFCs. Methods We searched several databases from inception through 31 August 2017 to identify comparative studies using endoscopic or percutaneous drainage for PFCs. Our primary outcome was clinical success. Secondary outcomes were technical success, adverse events (AE), rates of recurrence, requirement for subsequent procedures, and length of stay in hospital. Pooled risk ratios (RR) and mean difference (MD) were calculated for categorical and continuous outcomes, respectively. Results Seven studies with 490 patients were included in the final analysis. Pooled RR for clinical success was 0.40 (0.26, 0.61), I 2 = 42 % in favor of endoscopic management. On sensitivity analysis, after excluding one study on patients with walled-off necrosis (WON), the clinical success was 0.43 (0.28, 0.66) with no heterogeneity. Pooled RR for technical success was 1.50 (0.52, 4.37) with no heterogeneity. Pooled RR for AE and rate of recurrence were 0.77 (0.46, 1.28) and 0.60 (0.29, 1.24), respectively. Pooled MD for length of stay in hospital and rate of re-intervention were – 8.97 (– 12.88, – 5.07) and – 0.66 (– 0.93, – 0.38), respectively, in favor of endoscopic drainage. Conclusions Endoscopic drainage should be the preferred therapeutic modality for PFCs compared to percutaneous drainage as it is associated with significantly better clinical success, a lower re-intervention rate, and a shorter hospital length of stay. This study was presented as an abstract at Digestive Disease Week 2017 in Chicago, USA.
Convection-driven spherical shell dynamos at varying Prandtl numbers

(abidged) Context: Stellar convection zones are characterized by vigorous high-Reynolds number turbulence at low Prandtl numbers. Aims: We study the dynamo and differential rotation regimes at varying levels of viscous, thermal, and magnetic diffusion. Methods: We perform three-dimensional simulations of stratified fully compressible magnetohydrodynamic convection in rotating spherical wedges at various thermal and magnetic Prandtl numbers (from 0.25 to 2 and 5, respectively). Results: We find that the rotation profiles for high thermal diffusivity show a monotonically increasing angular velocity from the bottom of the convection zone to the top and from the poles toward the equator. For sufficiently rapid rotation, a region of negative radial shear develops at mid-latitudes as the thermal diffusivity is decreased. This coincides with a change in the dynamo mode from poleward propagating activity belts to equatorward propagating ones. Furthermore, the cyclic solutions disappear at the highest magnetic Reynolds numbers. The total magnetic energy increases with the magnetic Reynolds number in the range studied here ($5-151$), but the energies of the mean magnetic fields level off at high magnetic Reynolds numbers. The differential rotation is strongly affected by the magnetic fields and almost vanishes at the highest magnetic Reynolds numbers. In some of our most turbulent cases we find that two regimes are possible where either differential rotation is strong and mean magnetic fields relatively weak or vice versa. Conclusions: Our simulations indicate a strong non-linear feedback of magnetic fields on differential rotation, leading to qualitative changes in the behaviors of large-scale dynamos at high magnetic Reynolds numbers. Furthermore, we do not find indications of the simulations approaching an asymptotic regime where the results would be independent of diffusion coefficients.
A Likelihood-Based Comparison of Macro Asset Pricing Models

We estimate asset pricing models with multiple risks: long-run growth, long-run volatility, habit, and a residual. The Bayesian estimation accounts for the entire likelihood of consumption, dividends, and the price-dividend ratio. We find that the residual represents at least 80% of the variance of the price-dividend ratio. Moreover, the residual tracks most recognizable features of stock market history such as the 1990's boom and bust. Long run risks and habit contribute primarily in crises. The dominance of the residual comes from the low correlation between asset prices and consumption growth moments. We discuss theories which are consistent with our results.
No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads.

BACKGROUND It is unclear whether energy-containing drinks, especially those sweetened with high-fructose corn syrup (HFCS), promote positive energy balance and thereby play a role in the development of obesity. OBJECTIVE The objective was to examine the satiating effects of HFCS and sucrose in comparison with milk and a diet drink. DESIGN The effects of four 800-mL drinks [corrected] containing no energy or 1.5 MJ from sucrose, HFCS, or milk on satiety were assessed, first in 15 men and 15 women with a mean (+/-SD) body mass index (BMI; in kg/m(2)) of 22.1 +/- 1.9 according to visual analogue scales (VAS) and blood variables and second in 20 men and 20 women (BMI: 22.4 +/- 2.1) according to ingestion of a standardized ad libitum meal (granola cereal + yogurt, 10.1 kJ/g). RESULTS Fifty minutes after consumption of the 1.5-MJ preload drinks containing sucrose, HFCS, or milk, 170%-mm VAS changes in satiety were observed. Glucagon-like peptide 1 (GLP-1) (P < 0.001) and ghrelin (P < 0.05) concentrations changed accordingly. Compensatory energy intake did not differ significantly between the 3 preloads and ranged from 30% to 45%. Energy intake compensations were related to satiety (r = 0.35, P < 0.05). No differences were observed between the effects of the sucrose- and HFCS-containing drinks on changes in VAS and on insulin, glucose, GLP-1, and ghrelin concentrations. Changes in appetite VAS ratings were a function of changes in GLP-1, ghrelin, insulin, and glucose concentrations. CONCLUSION Energy balance consequences of HFCS-sweetened soft drinks are not different from those of other isoenergetic drinks, eg, a sucrose-drink or milk.
In Vitro Antioxidant and Free Radical Scavenging Activity and Chemometric Approach to Reveal Their Variability in Green Macroalgae from South Andaman Coast of India

Total phenol, flavonoid, carotenoid and antioxidant activity of four green macroalgae (Halimeda tuna, Halimeda macroloba, Enteromorpha sp. and Acetabularia acetabulum) collected from South Andaman coast were analysed in this study. The results revealed that methanol extract of Enteromorpha sp. showed maximum phenolic, flavonoid and carotenoid content of 5.72±0.13 mg GAE/g, 21.15±1.05 mg RE/g and 47.78±0.46 μg/g respectively. All the analysed macroalgae species exhibited antioxidant activities in dose dependent manner among which Enteromorpha sp. demonstrated greater antioxidant potential. A. acetabulum exhibited greater ABTS (2, 2-azinobiz-3-ethylbenthiazoline-6-sulfonic acid) radical scavenging ability (92%) as evident by its low IC50 (6.30 mg/ml) in comparison to other species. Based on factor analysis, up to two principal components were chosen to explain variability in 10 independent phytochemicals. The antioxidant potential reveals their potential for future applications in medicine, dietary supplements as well as the natural source of immunostimulants.
Adolescent girls and pelvic inflammatory disease: experience and practices of emergency department pediatricians.

OBJECTIVE To describe the experience and practices of emergency department pediatricians in the United States related to the diagnosis and management of pelvic inflammatory disease (PID) in adolescent girls and to compare this experience with Centers for Disease Control and Prevention recommended management guidelines. DESIGN National telephone survey. SUBJECTS One hundred four pediatricians randomly selected from the 659 members of the Section on Emergency Medicine of the American Academy of Pediatrics. Response rate was 56%. MEASURES A 42-item structured interview questionnaire assessed physician demographics, practice characteristics, PID diagnosis and management, and attitudes about sexually transmitted diseases in adolescents. RESULTS Fifty-one (94%) of 54 emergency department pediatricians had diagnosed PID in adolescents at least once within the past 2 years, and 35 (69%) had diagnosed PID, on average, once per month or more. Less than half the pediatricians (23/51 [45%]) routinely recommended hospital admission for adolescents with PID as suggested by the Centers for Disease Control and Prevention, and among those treating adolescents with PID as outpatients,just over half (20/37 [54%]) arranged close follow-up within 72 hours of initiating antibiotic treatment. Although most emergency department pediatricians routinely suggested condom use (47/54 [87%]) and human immunodeficiency virus testing (34/54 [63%]) after diagnosing a sexually transmitted disease, a minority routinely provided contraceptive counseling (23/54 [43%]) or written partner notification (17/54 [31%]). Approximately two thirds of pediatricians surveyed indicated that they thought that the care of an adolescent with a sexually transmitted disease should be different from that of an adult (35/54 [65%]) and that this age group was more prone to medical complications (38/54 [70%]). CONCLUSIONS The results of this survey suggest that emergency department pediatricians frequently diagnose PID in adolescent girls and understand the high risk of medical complications in this age group, but their management is often less aggressive than that recommended by Centers for Disease Control and Prevention guidelines and sexually transmitted disease experts.