Miracle-dz/UniFAR-FTUs huggingface dataset:
Facts Are More Important Than Novelty

Despite increased attention to methodological rigor in education research, the field has focused heavily on experimental design and not on the merit of replicating important results. The present study analyzed the complete publication history of the current top 100 education journals ranked by 5-year impact factor and found that only 0.13% of education articles were replications. Contrary to previous findings in medicine, but similar to psychology, the majority of education replications successfully replicated the original studies. However, replications were significantly less likely to be successful when there was no overlap in authorship between the original and replicating articles. The results emphasize the importance of third-party, direct replications in helping education research improve its ability to shape education policy and practice.
Living with persistent rheumatoid arthritis: a BARFOT study

AIM AND OBJECTIVE To describe and understand the meaning of living with persistent rheumatoid arthritis. BACKGROUND A considerable number of patients with rheumatoid arthritis live with an ongoing active and symptomatic illness despite access to potent antirheumatic treatment. There is, however, a lack of knowledge about the meaning of living with this severe long-term illness, defined as persistent rheumatoid arthritis. DESIGN A descriptive design based on a hermeneutic phenomenological method was used. METHODS Ten adults with persistent rheumatoid arthritis and at least five years disease duration were interviewed. The interviews were analysed according to van Manen's method. RESULTS Living with persistent rheumatoid arthritis revealed four overall themes: an existence dominated by painful symptoms and treatment, radical changes and limitations in one's life, a continual struggle to cope with one's life and to master the illness, and a dependency on those who are close by and the world around. The lifeworld was affected to a varying extent and in various ways by the illness but also by the dependence on its treatment and care that was not experienced as sufficiently meeting needs in terms of security, access to and coordination of care as well as team and rehabilitation services. CONCLUSIONS Persistent rheumatoid arthritis and its treatment entail a radical effect on the person's life and quality of life. Current ordinary rheumatology care does not seem to meet the individual needs of the person with persistent rheumatoid arthritis in an optimal way. RELEVANCE TO CLINICAL PRACTICE A greater knowledge about and understanding of the person who lives with persistent rheumatoid arthritis is important for facilitating the development of care and the relief of suffering. A holistic alternative to conventional clinical practice, such as person-centred care, could be tested as an innovative model of care. Our findings might serve as material for educational and counselling purposes for healthcare professionals.
Fixed-weight on-line learning

Conventional artificial neural networks perform functional mappings from their input space to their output space. The synaptic weights encode information about the mapping in a manner analogous to long-term memory in biological systems. This paper presents a method of designing neural networks where recurrent signal loops store this knowledge in a manner analogous to short-term memory. The synaptic weights of these networks encode a learning algorithm. This gives these networks the ability to dynamically learn any functional mapping from a (possibly very large) set, without changing any synaptic weights. These networks are adaptive dynamic systems. Learning is online continually taking place as part of the network's overall behavior instead of a separate, externally driven process. We present four higher order fixed-weight learning networks. Two of these networks have standard backpropagation embedded in their synaptic weights. The other two utilize a more efficient gradient-descent-based learning rule. This new learning scheme was discovered by examining variations in fixed-weight topology. We present empirical tests showing that all these networks were able to successfully learn functions from both discrete (Boolean) and continuous function sets. Largely, the networks were robust with respect to perturbations in the synaptic weights. The exception was the recurrent connections used to store information. These required a tight tolerance of 0.5%. We found that the cost of these networks scaled approximately in proportion to the total number of synapses. We consider evolving fixed weight networks tailored to a specific problem class by analyzing the meta-learning cost surface of the networks presented.
The Baryon asymmetry in the Standard Model with a low cut-off

We study the generation of the baryon asymmetry in a variant of the standard model, where the Higgs field is stabilized by a dimension-six interaction. Analyzing the one-loop potential, we find a strong first order electroweak phase transition for Higgs masses up to at least 170 GeV. Dimension-six operators induce also new sources of CP violation. We compute the baryon asymmetry in the WKB approximation. Novel source terms in the transport equations enhance the generated baryon asymmetry. For a wide range of parameters the model predicts a baryon asymmetry close to the observed value.
Adolescents' Goal Orientations in Society and the Educational Context: A Dutch‐Swedish comparative study

The purpose of this article is to examine whether 13‐year‐old pupils in Sweden and the Netherlands have similar or different goal orientations for going to school and learning. For this purpose a cross‐national comparative study was conducted involving 717 Dutch and 7391 Swedish pupils. The findings suggest that while goal orientations—constituted by different types of subgoals—seem to be culturally independent, the contents of these orientations are not. The results also suggest that there are considerable differences between the Dutch and Swedish education systems and the way Dutch and Swedish pupils perceive similar aspects of the educational process.
Schauder estimates, Harnack inequality and Gaussian lower bound for Kolmogorov-type operators in non-divergence form

We prove some Schauder type estimates and an invariant Harnack inequality for a class of degenerate evolution operators of Kolmogorov type. We also prove a Gaussian lower bound for the fundamental solution of the operator and a uniqueness result for the Cauchy problem. The proof of the lower bound is obtained by solving a suitable optimal control problem and using the invariant Harnack inequality.
Effectiveness of family training and life skills on caring chronic mental disorders in an Iranian population

This research is semi-empirical study which is done to examining the effectiveness of family trainings and life skills on Caring Chronic Mental Disorders in Mashhad (Iran). 300 participants has been chosen in randomly from the families of chronic mental disorders who has been admitted in round the clock centers in Mashhad and who had been in waiting list and these participants has been divided to two groups of experiment and control randomly and we introduce family trainings and life skills to experiment group. There was no training to control group. These two groups were tested period to the beginning of trainings and post training with instruments such as California Social Adjustment Questionnaire; Families' Attitude and Awareness about Life Skills and Family Trainings; Rosenberg Self-Esteem; General Health Questionnaire;and Symptom Checklist-90-Revised. Results indicated that training had no effect on the attitude of families toward taking care of mental disorder, but family member،s attitude toward mental disorder has been changed. This training has been influential on changing family member،s attitude toward life skills, social adjustment, self esteem, mental health increase and reducing mental disorders. Keywords: family, life skills, chronic mental disorders.
Folding patterns of porin and bacteriorhodopsin.

Porin spans the outer membrane of Escherichia coli with most of the protein embedded within the membrane. It lacks pronounced hydrophobic domains and consists predominantly of beta‐pleated sheet. These observations require the accommodation of polar and ionizable residues in an environment that has a low dielectric constant. Owing to a currently limited understanding of the constraints governing membrane protein structure, a minimal approach to structure prediction is proposed that identifies segments causing polypeptides to reverse their direction (turn identification). The application of this procedure avoids hydrophobicity parameters and yields a model of porin which is in good agreement with all experimental data available. The presence of polar and ionizable residues within membrane boundaries implies a dense (saturating) network of hydrogen bond donor and acceptor groups. Application to a paradigm of hydrophobic membrane proteins, bacteriorhodopsin, reveals a pattern consistent with its alpha‐helical folding. The postulated structure includes significantly more polar residues in the membrane domain than have been assumed previously, suggesting that there are also hydrogen bonding networks in bacteriorhodopsin. Extensive networks permeating protein interior and surfaces would explain the extraordinary stability and the tight interactions between functional units in the formation of crystalline arrays of both proteins.
Date Rape

This study examined the impact of perceived token resistance and previous sexual contact on men's discrimination of when a female wants her partner to stop his sexual advances. Male college students were randomly assigned to one of four conditions. Before listening to an audiotape of a date rape, subjects were told that the couple had been on five dates. On the previous date, the man had manipulated the woman's breasts or genitals. Subjects were also told that the woman did not object to this contact, or that she initially objected to the contact but subsequently stopped resisting the contact. Relative to subjects in the no-resistance condition, subjects in the perceived token resistance conditions took significantly longer to determine that the man should refrain from attempting further sexual contact. The implications of the findings are discussed.
LaZnB5O10, the first lanthanum zinc borate

Lanthanum zinc pentaborate, LaZnB5O10, was synthesized by flux-supported solid-state reaction. It is a member of the LnMB5O10 (Ln = rare earth ion and M = divalent metal ion) structure type. The crystal shows a three-dimensional structure constructed from two-dimensional {[B5O10]5−}n layers with the lanthanum (coordination number nine) and zinc (coordination number six) ions filling in the interlayers.
Hypoglycemia perception: Cross-cultural differences in Punjabi and Hindi speaking postmenopausal women

Introduction: The cross cultural differences in perception of menopausal symptoms are well known and these differences in perception of hypoglycemic symptoms in Russian-speaking and Caucasian postmenopausal women have been reported. Aims and objectives: This study assessed cross – linguistic and cross – cultural differences in symptomatology of self reported hypoglycemia, between Punjabi and Hindi speaking diabetic post menopausal women. Material and Methods: Thirty Punjabi speaking and 20 Hindi speaking diabetic postmenopausal women aged over 50 years, were recruited for this study. Each subject was asked, what happens to you when you have low sugar? in the language of her choice, and spontaneous answers were recorded verbatim. Statistical analysis: The data so obtained was analyzed by paper and pen method to obtain an understanding of the frequency of self reporting of various symptoms and then analyzed using Statistical Package for Social Science ver.19. 0. Results: Symptoms of hollowness, cold sweats and headache correlated significantly (P < 0.0001, P = 0.0001 and P = 0.03 respectively). One difference was noted in women from rural vs. urban background: Inability to concentrate was more frequent in urban women (4/23) vs rural women (0/27) (P < 0.0001). Discussion: To our knowledge, this is the first exploratory work highlighting the differences in self reported hypoglycemia symptomatology, based on linguistic background. In India and other countries with multi ethnic, multi linguistic societies, linguistic competence in hypoglycemia history taking is important. Limitations: Incidence of hypoglycemia in the subjects enrolled was not assessed. Many of the subjects in the Punjabi speaking cohort were bilingual. Some symptoms of hypoglycemia may have been missed or over-reported by participants. Conclusion: Diabetes care professionals should be aware that persons with diabetes from varying linguistic backgrounds may report symptoms of hypoglycemia differently.
MicroRNA regulation of T‐cell differentiation and function

MicroRNAs (miRNAs) are emerging as key controllers of T‐cell differentiation and function. Their expression is dynamically regulated by extracellular signals such as costimulation and cytokine signals. miRNAs set thresholds for gene expression and optimize protein concentrations of genetic networks. Absence of individual miRNAs can lead to severe immune dysfunction. In this study, we review emerging principles and provide examples of important functions exerted by miRNAs. Although our understanding of miRNA function in T‐cell differentiation is still rudimentary, the available evidence leaves no doubt that these small post‐transcriptional regulators are indispensable for proper functioning of the immune system.
HTTP adaptive streaming and access router management: The users' and network's perspectives

The share of video streaming in the Internet traffic is expected to reach 80% by 2019. To deliver these video services in possibly strained settings and to meet with the users requirement of anywhere and multi-screen experience, HTTP Adaptive Streaming (HAS) is gaining momentum. However, TCP-transport of HAS flows is known to entail a number of issues both on Quality of Experience (QoE) and network metrics. Thanks to testbed experiments, we examine the video streaming performance in a home access scenario by exposing the interplay between the video rate adaptation logic (Buffer-Based-BBA, or Rate-Based-RBA) and the buffer sizes and policies (Droptail, Active Queue Managements - AQMs). A main finding is that AQMs move the bulk of TCP losses from the initial burst and ACK-trailing phases, problematic to HAS flows, to the more favorable ACK-clocking phase. We thereby show that implementing AQM CoDel at the access router is a simpler means, working for any family of client's adaptation, to improve QoE and network metrics than striving to smooth out the HAS bursts by pacing at the client or middleboxes, as previous approaches do.
Successful enterprise resource planning implementation: taxonomy of critical factors

– The purpose of this paper is to investigate the current literature base of critical success factors (CSFs) of enterprise resource planning (ERP) implementations, provide a systematic compilation of CSFs, and present a new comprehensive taxonomy of CSFs for ERP system implementation. , – This paper compiles literature that highlighted possible references to CSFs for ERP implementation projects. Given that the purpose of this paper is to achieve a depth of understanding of the various CSFs already identified by other researchers, “content analysis” is used. Four stages of content analysis are adopted to collect and analyse the literature, i.e. data collection, open coding, axial coding, and selective coding. , – By analyzing all CFSs mentioned in literature during the last ten years (1999‐2008), taxonomy of ERP CSFs implementation was formulated. In total 17 CSFs were identified, which is then categorized into five main categories. , – Literature is collected from selected databases and journals from 1999 to 2008. , – This paper is significant because taxonomy helps us organize the knowledge. Taxonomy can help the researchers to make their search easier by assigning CSFs to a category and defining relationships between those categories. , – The output of this paper will help future researchers to increase identification of related studies in the literature review phase of their work.
Peginterferon alfa-2a/ribavirin for 48 or 72 weeks in hepatitis C genotypes 1 and 4 patients with slow virologic response.

BACKGROUND & AIMS This randomized multicenter trial evaluated individualization of treatment duration with peginterferon alfa-2a 180 microg/wk plus ribavirin 1000/1200 mg/day in patients with chronic hepatitis C genotype 1/4 based on the rapidity of virologic response (VR). METHODS Patients with a rapid VR (RVR; undetectable hepatitis C virus [HCV]-RNA level (<50 IU/mL at week 4) were treated for 24 weeks, those with an early VR (EVR; no RVR but undetectable HCV-RNA level or >or=2-log(10) decrease at week 12) were randomized to 48 (group A) or 72 weeks of treatment (group B; peginterferon alfa-2a was reduced to 135 microg/wk after week 48). Patients without an EVR continued treatment until week 72 if they had undetectable HCV-RNA levels at week 24. The primary end point was relapse; sustained VR (SVR; undetectable HCV-RNA level after 24 weeks of follow-up evaluation) was a secondary end point. RESULTS Of 551 genotype 1/4 patients starting treatment, 289 were randomized to group A (N = 139) or group B (N = 150). The relapse rate was 33.6% in group A (95% confidence interval [CI], 24.8%-43.4%) and 18.5% in group B (95% CI, 11.9%-27.6%; P = .0115 vs group A) and the SVR rate was 51.1% (95% CI, 42.5%-59.6%) and 58.6% (95% CI, 50.3%-66.6%; P > .1), respectively. The overall SVR rate was 50.4% (278 of 551; 95% CI, 46.2%-54.7%), including 115 of 150 patients with an RVR treated for 24 weeks and 4 of 78 patients without an EVR. CONCLUSIONS Extending therapy with peginterferon alfa-2a/ribavirin to 72 weeks decreases the probability of relapse in patients with an EVR. If they can be maintained on extended-duration therapy, SVR rates also may improve.
The Impact of Financial Incentives on Physician Behavior in Managed Care Plans: A Review of the Evidence

This review examines the relationship between the financial incentives confronting physicians in managed care plans and the utilization of services. The primary conclusion of this review is that the financial incentives confronting physicians are a key element in explaining the lower utilization rates of enrollees in managed care plans. However, this conclusion is not definitive because it is based on studies that are subject to numerous sources of potential bias. To isolate the impact of financial incentives facing physicians on the performance of health plans, it is necessary to adjustor patient, physician, health plan, and market characteristics related to utilization, and most studies include little information about these characteristics.
Oral symptoms significantly higher among long-term khat (Catha edulis) users in Ethiopia

OBJECTIVES: Associations between khat (Catha edulis) chewing and different adverse oral-dental health conditions have been reported, yet evidence is still lacking. This study was designed to investigate the association between long-term regular khat chewing and self-reported oral symptoms. METHODS: A cross-sectional study was conducted on a sample of 1,255 university students in southern Ethiopia. Data on khat chewing status, a range of oral symptoms and other pertinent variables were collected using self-administered questionnaires. The association between long-term regular khat chewing and oral symptom count was investigated using negative binomial regression. RESULTS: The mean oral symptom count among long-term regular khat chewers was 1.75 (standard deviation [SD], 2.18; standard error [SE], 0.31), whereas that among those who were not long-term regular khat chewers was 1.18 (SD, 1.68; SE, 0.10). After adjustment for other variables, long-term regular khat chewers had approximately 50% more oral symptoms than those who were not long-term chewers did (adjusted count ratio, 1.53; 95% confidence interval, 1.12 to 2.10). CONCLUSIONS: Long-term khat chewing negatively affects the oral health of young university students.
Efficacy of vitamin D3 supplementation in preventing fractures in elderly women: A meta-analysis

Abstract Background: The efficacy of vitamin D3 in preventing fractures and falls has been explored in a number of clinical trials. However, recent evidence revealed new questions about the adequate doses of vitamin D3 supplementation and its efficacy in fracture prevention independent of calcium supplements for various types of fractures. Objective: To conduct a meta-analysis to estimate the effectiveness of 800 IU daily vitamin D3 supplementation for increasing bone mineral density (BMD) and preventing fractures in postmenopausal women. Methods: Medline and EMBASE were searched for controlled trials comparing the effectiveness of cholecalciferol (vitamin D3) against placebo with or without background calcium supplementation in the treatment of postmenopausal women. Results: Eight controlled trials evaluating the effect of vitamin D3 supplementation with or without calcium were assessed. Of 12 658 women included in a Bayesian meta-analysis, 6089 received vitamin D3 (with or without calcium) and 6569 received placebo (with or without calcium). Compared to placebo, vitamin D3 with calcium supplementation showed beneficial effects on the incidence of non-vertebral (odds ratio [OR] 0.77, 95% credibility limit [CL] 0.6–0.93) and hip (OR 0.70, 95% CL 0.53–0.90) fractures, while the effects on non-vertebral-non-hip fractures (OR 0.84, 95% CL 0.67–1.04) % point increase) were associated with more uncertainty. Vitamin D3 supplementation showed a 70% probability of being a better treatment than placebo for the prevention of non-vertebral fractures, hip fractures, and non-vertebral, non-hip fractures. Compared to calcium supplementation, vitamin D3 plus calcium reduced non-vertebral fractures (OR 0.68, 95% CL 0.43–1.01) and non-vertebral, non-hip fractures (OR 0.64, 95% CL 0.38–0.99), but did not reduce hip fractures (OR 1.03, 95% CL 0.39–2.25). Key limitations to this analysis include a small number of studies and heterogeneity in the study populations. Conclusions: This meta-analysis supports the use of vitamin D3 of 800 IU daily to reduce the incidence of osteoporotic non-vertebral, hip, and non-vertebral-non-hip fractures in elderly women. Vitamin D3 with calcium appears to achieve benefits above those attained with calcium supplementation alone for non-vertebral and non-vertebral-non-hip fractures.
Fused timing analytical model for repeater insertion and optimization

In this paper, an analytical model for interconnections considering the transmission line model, short channel effects and ramp waveforms, is proposed. Closed form expressions for number of stages and transistor width are derived. It is shown that the proposed unified model provides smaller delays with smaller transistors. AMS 0.35/spl mu/m and Berkeley 0.13/spl mu/m technology parameters were used for the analysis and comparison. The model is used to design H trees and coupled rings arrays. For 0.13/spl mu/m technology and more than three stages, the maximum error obtained is 5% when compared with HSpice.