Miracle-dz/UniFAR-FTUs huggingface dataset:
Longitudinal Road Profile Spectrum Approximation by Split Straight Lines

The presented study compares three alternative straight-line approximations of the longitudinal road-profile power spectral density (PSD). The one straight line and two and three split straight-line approximations were analyzed. The minimizing of the root-mean-squared error (RMSE) was used as criteria of goodness of fit for the approximation models. The statistics of the PSD approximation model parameters, i.e., unevenness index, waviness, break angular spatial frequency, and the standard error of the regression for 145 test sections from the long-term pavement performance program (SPS-6) were calculated. The approximations were compared with connected versus unconnected lines. The approximation with two connected lines seems to be a reasonable substitution of a raw spectrum. A mean improvement of approximately 35% compared to the one straight-line approximation was identified.
The nature of the ghost cavity in the NGC 741 group

We discuss the effects of energy injection into the intragroup medium of the group of galaxies associated with NGC 741. The X-ray emission reveals a large bubble, which in the absence of a currently bright central radio source may have been inflated by a previous cycle of nuclear activity. If the bubble is filled with a light, relativistic fluid, we calculate that in expanding, it has done more than sufficient work to counteract the energy lost from the intragroup medium via radiative cooling; the bubble can provide this energy as it expands and rises. Using upper limits on the flux density of the plasma filling the bubble at 330 MHz and 1.4 GHz, we derive constraints on its electron energy distribution and magnetic field strength. We show that the data require the high-energy cut-off of the electron spectrum to be very low compared to the cut-offs seen in more typical radio sources if the fluid filling the bubble is a conventional relativistic plasma. This suggests that the fluid filling the bubble may not have evolved by expansion or synchrotron losses consistent with a dead radio source, leaving a puzzle as to what the origin of the bubble may be.
Teams That Finish Early Accelerate Faster: A Pattern Language for High Performing Scrum Teams

Recent surveys show that 42% of Agile projects are successful. While this is three times better than traditional projects, 49% of Agile projects are late or over budget and 9% are total failures [1]. There is a better way to help Agile teams to implement Scrum. At the 2013 Scrum PLoP Conference held in Tisvildeleje, Denmark thought leaders in the Agile community reviewed a set of Scrum Patterns that together generate a high performing Scrum team. During this editorial process it became apparent that a combination of nine Patterns in conjunction with the Scrum framework could help teams achieve Hyper-Productivity, more than a 400% increase in velocity over a team's initial velocity.
Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study

Human hypertension arises from a combination of genetic factors and lifestyle influences. With cardiovascular disease set to become the number 1 cause of death worldwide, it is important to understand the etiologic mechanisms for hypertension, because these might provide new routes to improved treatment. The British Genetics of Hypertension Study has recently published a primary genome screen that identified 4 chromosomal regions of interest. We have now genotyped additional markers to confirm the most promising regions for follow-up studies. Thirty-four additional microsatellites were genotyped in our severely hypertensive affected sibling pair resource (now 1635 families with 2142 affected sibling pairs), leading to a substantial increase in information content in the regions of interest. We found increased support for linkage of chromosome 5q13 to human hypertension (multipoint logarithm of odds=2.50) with 3 adjacent markers yielding single point logarithm of odds scores of 3.22, 2.84, and 2.51. The placement of additional markers on 2q, 6q, and 9q diminished support for linkage in these regions. However, the addition of new data and families identified novel regions of interest on chromosomes 1q and 11q. The 3 positive markers in the chromosome 5 region were also genotyped in 712 distinct parent–offspring trios with the same severe phenotype to replicate linkage and association. Borderline support for replication was found (P=0.07). We found increased evidence for linkage and borderline-significant evidence for association for a hypertension susceptibility locus on chromosome 5q13 that is worthy of detailed fine mapping and assessment of candidate genes.
Synergistic Defensive Function of Raphides and Protease through the Needle Effect

Raphides, needle-shaped calcium oxalate crystals in tissues of many plants, have been thought to play defensive roles against herbivores without detailed bioassays for their defensive roles and modes of function using purified raphides. In order to examine the defensive roles and modes of function of raphides in a clear experimental system, we performed bioassays giving the larvae of the Eri silkmoth, Samia ricini (Saturniidae), leaves of their host plant, the castor oil plant, Ricinus communis (Euphorbiaceae), painted with the raphides purified from kiwifruits, Actinidia deliciosa (Actinidiaceae), in presence or absence of cysteine protease, which often coincide with raphides in plant tissues. Raphides alone or cysteine protease alone showed only weak defensive activities around experimental concentrations. However, when raphides and cysteine protease coexisted, they synergistically showed very strong growth-reducing activities, and the mortality of caterpillars was very high. In contrast, amorphous calcium oxalate did not show synergism with cysteine protease on defensive activities, indicating that the needle-shape of raphides is essential for the synergism. The present study provides the first clear experimental evidence for the synergism between raphides and other defensive factors. Further, the study suggests that “the needle effect”, which intensify the bioactivities of other bioactive factors by making holes to the barriers (cell membrane, cuticle, epithelium, the nuclear membrane, etc.) and facilitate the bioactive factors to go through them and reach the targets, is important in the defensive activities of raphides, and possibly in the allergy caused by raphides, and in the carcinogenic activities of other needle-shaped components including asbestos and plant derived silica needles.
Electronic properties of Cs-intercalated single-walled carbon nanotubes derived from nuclear magnetic resonance

We report on the electronic properties of Cs-intercalated single-walled carbon nanotubes (SWNTs). A detailed analysis of the 13C and 133Cs nuclear magnetic resonance (NMR) spectra reveals an increased metallization of the pristine SWNTs under Cs intercalation. The ‘metallization’ of CsxC materials where x=0–0.144 is evidenced from the increased local electronic density of states (DOS) n(EF) at the Fermi level of the SWNTs as determined from spin–lattice relaxation measurements. In particular, there are two distinct electronic phases called α and β and the transition between these occurs around x=0.05. The electronic DOS at the Fermi level increases monotonically at low intercalation levels x<0.05 (α-phase), whereas it reaches a plateau in the range 0.05⩽x⩽0.143 at high intercalation levels (β-phase). The new β-phase is accompanied by a hybridization of Cs(6s) orbitals with C(sp2) orbitals of the SWNTs. In both phases, two types of metallic nanotubes are found with a low and a high local n(EF), corresponding to different local electronic band structures of the SWNTs.
Fate of the H-NS–Repressed bgl Operon in Evolution of Escherichia coli

In the enterobacterial species Escherichia coli and Salmonella enterica, expression of horizontally acquired genes with a higher than average AT content is repressed by the nucleoid-associated protein H-NS. A classical example of an H-NS–repressed locus is the bgl (aryl-β,D-glucoside) operon of E. coli. This locus is “cryptic,” as no laboratory growth conditions are known to relieve repression of bgl by H-NS in E. coli K12. However, repression can be relieved by spontaneous mutations. Here, we investigated the phylogeny of the bgl operon. Typing of bgl in a representative collection of E. coli demonstrated that it evolved clonally and that it is present in strains of the phylogenetic groups A, B1, and B2, while it is presumably replaced by a cluster of ORFans in the phylogenetic group D. Interestingly, the bgl operon is mutated in 20% of the strains of phylogenetic groups A and B1, suggesting erosion of bgl in these groups. However, bgl is functional in almost all B2 isolates and, in approximately 50% of them, it is weakly expressed at laboratory growth conditions. Homologs of bgl genes exist in Klebsiella, Enterobacter, and Erwinia species and also in low GC-content Gram-positive bacteria, while absent in E. albertii and Salmonella sp. This suggests horizontal transfer of bgl genes to an ancestral Enterobacterium. Conservation and weak expression of bgl in isolates of phylogenetic group B2 may indicate a functional role of bgl in extraintestinal pathogenic E. coli.
Longitudinal Relations Among Self-Concept, Intrinsic Value, and Attainment Value Across Secondary School Years in Three Academic Domains

This study expanded on research on temporal relations among motivation constructs as stated by expectancy-value theory, which has so far neglected the differentiation of value facets, the examination of long time spans with multiple measurement waves, and domain-specific patterns of findings. We examined the longitudinal relations among academic self-concept, intrinsic value, and attainment value in the three domains of math, German, and English across 5 annual measurement waves covering Grades 5 to 9 with German secondary school students (N = 2,116). The analyses based on cross-lagged panel models. In math and English, former academic self-concept was positively related to later intrinsic value and attainment value. In German, former intrinsic value and attainment value were positively related to later academic self-concept. The cross-lagged relations among value constructs varied according to the domain, hinting at the domain specificity of findings. The relations among academic self-concept, intrinsic value, and attainment value in the 3 domains did not change in size across students’ secondary school years. In addition, the pattern of all relations remained stable when controlling for students’ domain-specific achievement measured by school grades in the respective domains.
How to Promote Trust: Theory and Evidence from China

Economists have long recognized the importance of trust, but how can trust be enhanced in a marketplace? We set up a rational expectation model that allows the marketplace to target buyer trusting (via a buyer protection program) and seller trustworthiness (via penalty on cheaters) separately. We show that these two policies have opposite eects on the equilibrium level of trust: buyer protection increases buyer willingness to trade and therefore invites strategic sellers to enter and cheat; in contrast, a penalty on cheating sellers raises the cost of cheating and leads to more honest behavior. Using transaction-level data from Eachnet.com (an eBay equivalent in China), which introduced dierent buyer protection policies and a warning system in its early time, we nd evidence highly consistent with the theory. More generous buyer protection led to more seller cheating. In particular, sellers that entered the market after the introduction of buyer protection were more likely to cheat and became more trustworthy when the platform adopted the warning system. Reputable sellers were less likely to cheat, but this eect was weakened after the introduction of buyer protection and the warning system. These ndings suggest that a trust-promoting policy aimed at buyer trusting may not be eective if it is not accompanied by additional incentives to improve trustworthiness.
On the Measurement and Impact of Fiscal Decentralization

The typical post-Bretton Woods era development approach that emphasized central government-led development efforts has changed dramatically, and local governments have clearly emerged as players in development policy. The thinking about what is important to achieve in development objectives is changing as fiscal decentralization reforms are being pursued by many countries around the world. In this context, a number of studies have attempted to quantify the impact of decentralization by relating some measure of it to economic outcomes of fiscal stability, economic growth, and public sector size. But decentralization is surprisingly difficult to measure. Nearly all cases examining the relationship between decentralization and macroeconomic performance have relied on the Government Finance Statistics (GFS) of the International Monetary Fund. However, despite its merits, GFS falls short in providing a full picture of fiscal decentralization. For some countries, however, there is data that more accurately captures fiscal responsibilities among different types of governments.
Hospitalization and cost after switching from atypical to typical antipsychotics in schizophrenia patients in Thailand

Background Several clinical practice guidelines suggest using atypical over typical antipsychotics in patients diagnosed with schizophrenia. Nevertheless, cost-containment policy urged restricting usage of atypical antipsychotics and switching from atypical to typical antipsychotics. Objective This study aimed to evaluate clinical and economic impacts of switching from atypical to typical antipsychotics in schizophrenia patients in Thailand. Methods From October 2010 through September 2013, a retrospective cohort study was performed utilizing electronic database of two tertiary hospitals. Schizophrenia patients aged 18 years or older and being treated with atypical antipsychotics were included. Patients were classified as atypical antipsychotic switching group if they switched to typical antipsychotics after 180 days of continual atypical antipsychotics therapy. Outcomes were schizophrenia-related hospitalization and total health care cost. Logistic and Poisson regression were used to evaluate the risk of hospitalization, and generalized linear model with gamma distribution was used to determine the health care cost. All analyses were adjusted by employing propensity score and multivariable analyses. All cost estimates were adjusted according to 2013 consumer price index and converted to US$ at an exchange rate of 32.85 Thai bahts/US$. Results A total of 2,354 patients were included. Of them, 166 (7.1%) patients switched to typical antipsychotics. The adjusted odds ratio for schizophrenia-related hospitalization in atypical antipsychotic switching group was 1.87 (95% confidence interval [CI] 1.23–2.83). The adjusted incidence rate ratio was 2.44 (95% CI 1.57–3.79) for schizophrenia-related hospitalizations. The average total health care cost was lower in patients with antipsychotic switching (−$64; 95% CI −$459 to $332). Conclusion Switching from atypical to typical antipsychotics is associated with an increased risk of schizophrenia-related hospitalization. Nonetheless, association with average total health care cost was not observed. These findings can be of use as a part of evidence in executing prospective cost-containment policy.
La question du réel : de la science à la catastrophe

Cet article tire profit des enseignements de la psychanalyse pour explorer la place que les « scientifiques » peuvent, et ne peuvent pas, tenir face aux demandes qui leur sont adresses. Il explore le transfert qui s'opere envers la Science au travers des figures du monstre et de la Catastrophe. Parce qu'elles confrontent l'individu et le collectif a la question du reel, de sa mise en discours et en recit, les situations de catastrophes permettent de souligner le caractere potentiellement traumatogene du projet scientifique, constat qui invite a distinguer la pratique de la recherche et la situation d'expertise.
Motivational Interactions: Effects on Behaviour

The "Motivation Crowding Effect" suggests that an external intervention via monetary incentives or punishments may undermine (or under different identifiable conditions strengthen) intrinsic motivation. "Crowding-out" and "crowding-in" are empirically relevant phenomena, which can, in specific cases, even dominate the traditional relative price effect. "Crowding effects" may also spread beyond the area and persons initially subject to "crowding-out" and "crowding-in". The paper discusses the conditions under which such a "Motivation Transfer Effect" may obtain.
Introducing PebbleCounts: a grain-sizing tool for photo surveys of dynamic gravel-bed rivers

Abstract. Grain-size distributions are a key geomorphic metric of gravel-bed rivers. Traditional measurement methods include manual counting or photo sieving, but these are achievable only at the 1–10 m2 scale. With the advent of drones and increasingly high-resolution cameras, we can now generate orthoimagery over hectares at millimeter to centimeter resolution. These scales, along with the complexity of high-mountain rivers, necessitate different approaches for photo sieving. As opposed to other image segmentation methods that use a watershed approach, our open-source algorithm, PebbleCounts, relies on k-means clustering in the spatial and spectral domain and rapid manual selection of well-delineated grains. This improves grain-size estimates for complex riverbed imagery, without post-processing. We also develop a fully automated method, PebbleCountsAuto, that relies on edge detection and filtering suspect grains, without the k-means clustering or manual selection steps. The algorithms are tested in controlled indoor conditions on three arrays of pebbles and then applied to 12 × 1 m2 orthomosaic clips of high-energy mountain rivers collected with a camera-on-mast setup (akin to a low-flying drone). A 20-pixel b-axis length lower truncation is necessary for attaining accurate grain-size distributions. For the k-means PebbleCounts approach, average percentile bias and precision are 0.03 and 0.09 ψ, respectively, for ∼1.16 mm pixel−1 images, and 0.07 and 0.05 ψ for one 0.32 mm pixel−1 image. The automatic approach has higher bias and precision of 0.13 and 0.15 ψ, respectively, for ∼1.16 mm pixel−1 images, but similar values of −0.06 and 0.05 ψ for one 0.32 mm pixel−1 image. For the automatic approach, only at best 70 % of the grains are correct identifications, and typically around 50 %. PebbleCounts operates most effectively at the 1 m2 patch scale, where it can be applied in ∼5–10 min on many patches to acquire accurate grain-size data over 10–100 m2 areas. These data can be used to validate PebbleCountsAuto, which may be applied at the scale of entire survey sites (102–104 m2). We synthesize results and recommend best practices for image collection, orthomosaic generation, and grain-size measurement using both algorithms.
Volatility Information Trading in the Option Market

This paper investigates informed trading on stock volatility in the option market. We construct non-market maker net demand for volatility from the trading volume of individual equity options and find that this demand is informative about the future realized volatility of underlying stocks. We also find that the impact of volatility demand on option prices is positive. More importantly, the price impact increases by 40% as informational asymmetry about stock volatility intensifies in the days leading up to earnings announcements and diminishes to its normal level soon after the volatility uncertainty is resolved. THE LAST SEVERAL DECADES have witnessed astonishing growth in the market for derivatives. The market’s current size of $200 trillion is more than 100 times greater than 30 years ago (Stulz (2004)). Accompanying this impressive growth in size has been an equally impressive growth in variety: The derivatives market now covers a broad spectrum of risk, including equity risk, interest rate risk, weather risk, and, most recently, credit risk and inflation risk. This phenomenal growth in size and breadth underscores the role of derivatives in financial markets and their economic value. While financial theory has traditionally emphasized the spanning properties of derivatives and their consequent ability to improve risk-sharing (Arrow (1964) and Ross (1976)), the role of derivatives as a vehicle for the trading of informed investors has emerged as another important economic function of these securities (Black (1975) and Grossman (1977)). We contribute to the body of knowledge on the economic value of derivatives by investigating the role of options as a mechanism for trading on information about future equity volatility. Our focus on informed volatility trading is motivated to a large extent by the fact that equity options are uniquely suited to investors with information about future volatility. Unlike traders with
Risk factors for early recurrent Clostridium difficile-associated diarrhea.

Recurrence is a common sequela of Clostridium difficile-associated diarrhea (CDD) and may increase morbidity, costs, and treatment-related antimicrobial resistance. Because recurrent CDD (RCDD) frequently occurs very soon after an initial episode, our goal was to determine the risk factors for early RCDD (occurring < or = 45 days after the initial episode). We conducted a case-control study, comparing 13 patients with early RCDD (case patients) with 46 patients who had only one CDD episode (control patients) at Centre Hospitalier Angrignon (Québec) during January 1993 through November 1994. Risk factors for early RCDD included a history of chronic renal insufficiency, a white blood cell count of > or = 15 x 10(3)/mm3, and community-acquired diarrhea with the first CDD episode. For seven of eight case patients, C. difficile strains from the first and second CDD episodes were identical, suggesting that relapse is more common than reinfection. These results suggest that treatments should be directed at preventing relapses in patients at high risk for early RCDD.
Treatment of Clinical Mastitis Caused by Specific Pathogens Streptococcus agalactiae : Strep

Introduction Mastitis continues to be the most frequent and costly disease of dairy cattle. Financial losses due to mastitis occur for both subclinical and clinical stages of the disease. Losses caused by subclinical mastitis are well documented. Each doubling of SCC above 50,000 cells/ml results in a loss of 0.4 kg and 0.6 kg of milk per day in first lactation and older cows, respectively (Hortet and Seegers, 1998). Losses caused by clinical mastitis include discarded milk, transient reductions in milk yield and premature culling (Fetrow, 2000). Perceived financial losses for clinical mastitis vary widely. In 2002-2003, farmers participating in milk quality programs in Wisconsin (n = 117) estimated that each clinical case of mastitis cost approximately $97.00 USD, but estimates ranged from zero to $260 per case. Discarded milk accounted for more than half of the cost ($54.00 USD).