Miracle-dz/UniFAR-FTUs huggingface dataset:
Objectivity and the Escape from Perspective

Scientific objectivity is neither monolithic nor immutable: our current usage is compounded of several meanings - metaphysical, methodological and moral - and each meaning has a distinct history, as well as a history of fusion within what now counts as a single concept of `objectivity'. The rise of aperspectival history in nineteenth-century science is one strand of this plaited history of objectivity, as embodied in scientific ideals and practices. It is conceptually and historically distinct from the ontological aspect of objectivity that pursues the ultimate structure of reality, and from the mechanical aspect of objectivity that forbids interpretation in reporting and picturing scientific results. Whereas ontological objectivity is about the fit between theory and the world, and mechanical objectivity is about suppressing the universal human propensity to judge and aestheticize, aperspectival objectivity is about eliminating individual (or occasionally group) idiosyncracies. It emerged first in the moral and aesthetic philosophy of the late eighteenth century and spread to the natural sciences only in the mid-nineteenth century, as a result of a reorganization of scientific life that multiplied professional contacts at every level, from the international commission to the well-staffed laboratory.
HABP2 is a Novel Regulator of Hyaluronan-Mediated Human Lung Cancer Progression

Background Lung cancer is a devastating disease with limited treatment options. Many lung cancers have changes in their microenvironment including upregulation of the extracellular matrix glycosaminoglycan, hyaluronan (HA), which we have previously demonstrated can regulate the activity of the extracellular serine protease, hyaluronan binding protein 2 (HABP2). This study examined the functional role of HABP2 on HA-mediated human lung cancer dynamics. Methods Immunohistochemical analysis was performed on lung cancer patient samples using anti-HABP2 antibody. Stable control, shRNA, and HABP2 overexpressing human lung adenocarcinoma cells were evaluated using immunoblot analysis, migration, extravasation, and urokinase plasminogen activator (uPA) activation assays with or without high-molecular weight HA or low-molecular weight HA (LMW-HA). In human lung cancer xenograft models, primary tumor growth rates and lung metastasis were analyzed using consecutive tumor volume measurements and nestin immunoreactivity in nude mouse lungs. Results We provide evidence that HABP2 is an important regulator of lung cancer progression. HABP2 expression was increased in several subtypes of patient non-small cell lung cancer samples. Further, HABP2 overexpression increased LMW-HA-induced uPA activation, migration, and extravasation in human lung adenocarcinoma cells. In vivo, overexpression of HABP2 in human lung adenocarcinoma cells increased primary tumor growth rates in nude mice by ~2-fold and lung metastasis by ~10-fold compared to vector control cells (n = 5/condition). Conclusion Our data suggest a possible direct effect of HABP2 on uPA activation and lung cancer progression. Our observations suggest that exploration of HABP2 in non-small cell lung carcinoma merits further study both as a diagnostic and therapeutic option.
Speed Dating: a Process of Forming Undergraduate Student Groups

First year undergraduate students working on semester-long group assessments may lack the skills and knowledge to make sound choices in selecting other group members. This paper is an instructor's guide to using speed-dating techniques in a classroom environment to create student groups. The paper also outlines suggestions for lecturers on how to support their students in the experience, based on theoretical constructs around the psychology of choice and work teams.
A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection

Major histocompatibility complex (MHC) class II (A beta) knockout mice were vaccinated with ts-4, an attenuated mutant strain of Toxoplasma gondii, which in normal animals induces strong T cell immunity mediated by interferon gamma (IFN-gamma). After challenge with the lethal parasite strain RH, the knockout mice displayed decreased resistance consistent with absence of CD4+ effectors. Nevertheless, these animals generated CD8+ lymphocyte effectors capable of mediating partial protection through IFN-gamma secretion. Moreover, in vivo neutralization experiments indicated that the development of resistance in knockout mice depends on CD4+ cells as well as interleukin 2 (IL-2). The identity of the IL-2-producing protective cell population was further characterized as CD4+, NK1.1+ by in vitro depletion studies and reverse transcriptase-PCR analysis of fluorescence-activated cell sorter (FACS)-purified CD4+ NK1.1+ T lymphocytes. These results demonstrate that in the absence of conventional MHC class II-restricted CD4+ T lymphocytes, CD8 priming persists and mediates partial protective immunity to T. gondii. Moreover, the data argue that CD4+, NK1.1+ cells, previously implicated in the initiation of T helper cell 2 (Th2) responses through their production of IL-4, can also play a role as alternative IL-2-secreting helper cells in Th1-mediated host resistance to infection.
Evidence for utilitarian motives in emotion regulation

This investigation demonstrates that emotion regulation can be driven by considerations of utility per se. We show that as participants prepared for a negotiation, those who were motivated to confront (vs. collaborate with) another person believed that anger would be more useful to them. However, only participants who were motivated to confront another and expected to receive a monetary reward for their performance (i.e., high utility), were motivated to increase their anger in preparation for the negotiation. Participants who were motivated to confront another but did not expect their performance to be rewarded (i.e., low utility), did not try to increase their anger, even though they expected anger to be useful in the negotiation. Such patterns demonstrate that people are motivated to experience even unpleasant emotions to maximise utility.
Fatigue Properties of Highly Oriented Polypropylene Tapes and All-Polypropylene Composites

This paper describes the fatigue behaviour of newly developed all-polypropylene (all-PP) tapes and composites, with reference to the composite processing conditions, testing temperature and making a comparison with commercial alternatives. All-PP tapes are highly oriented and their failure behaviour follows that of other highly oriented polymers. All-PP woven composites fail ultimately due to PP tape failure. However, this failure mode is accompanied by delamination of fabrics in the woven structure. Consolidation pressure plays a decisive role in controlling the interlaminar properties and hence the delamination resistance and furthermore the fatigue limit of the composite. Comparison of all-PP woven composites with commercial alternatives based on glass and natural fibres reveals the excellent relative performance of all-PP composites under fatigue loads. Fatigue properties of all-PP composites are however sensitive to the testing temperature, and elevated temperatures can lead to a rapid reduction of the fatigue resistance of these all-polymer systems.
The Morality of Play

Over the last several decades, video games have become one of America’s most popular pastimes. Sadly, little academic work has studied media coverage of video games during this transformation. Williams’ analysis of news magazines’ coverage from 1970 to 2000 offers the only research into this topic. However, the video game industry has significantly changed since 2000. To remedy this gap, I examine video game coverage in The New York Times over the last three decades. During this period, evaluative articles primarily treat video games as a major threat. However, a small subset of articles rejects this portrayal. During the 1980s and 1990s, this alternative account identifies video games’ functional benefits. This narrative changes in the 2000s to celebrating video games’ artistic merits. My work contributes to the social construction of technology literature in general by documenting how civil society’s cultural understanding of children and entertainment influence the specific narratives The New York Times attaches to video games.
Accuracy of urine dipstick to predict urinary tract infections in an emergency department.

BACKGROUND Urine dipstick is a useful and commonly used test in the Emergency Department because of its rapidity and low cost; however its diagnostic accuracy is debatable. Our objective was to compare the urine dipstick and urinalysis for Urinary Tract Infection in a developing country, where there are significant cost considerations. METHODS This was an observational study of adults' patients presenting to Section of Emergency section (SEM) of the Aga Khan University Hospital, from March to May 1998. The patient's urine sample was tested immediately, using the Multistix 10SG. The sample was sent within one hour to the hospital laboratory for analysis, while the urinary specimen was sent for culture, where appropriate. The dipstick results were compared with the results of automated urinalysis in the laboratory, leukocyte counts on microscopy and urine culture. Sensitivity, Specificity, and predictive values were also calculated. RESULTS We evaluated 984 samples of urine during the study period. The sensitivity of nitrite test was 81% and that of leukocyte esterase 77% for positive cultures. However, the sensitivity for combined nitrite and leukocyte esterase test was 94%. Nitrite test was more specific (87%) than leukocyte esterase test (54%) or both tests taken together (50%). The predictive value of nitrite and leukocyte esterase together for a negative urine culture was 95%. Leukocyte esterase test sensitivity increased as the number of white blood cells on microscopy increased. Similarly the predictive value of leukocytes on microscopy for a positive culture increased as the number of leukocytes increased. CONCLUSION Dipstick alone cannot accurately predict urinary tract infection in emergency department.
The Specificity of Autobiographical Memories in Early Adolescence

Although autobiographical memory specificity is an important developmental feature fostering adaptation throughout life, little is known about factors related to interindividual differences in autobiographical memory specificity. The current study investigated associations with early adolescents’ communication with mother about their experiences and their trust in her support. For this reason, 80 general population children (ages ranging from 10 to 13) were asked to retrieve specific memories of interactions with mother. Communication and trust in maternal support were measured using questionnaires. Results showed that specificity of autobiographical memories was directly linked with communication, but not with trust in maternal support. Moreover, evidence was found in favor of an indirect effect of trust on autobiographical memory specificity through communication. This study suggests that trust-related mother-child communication is important to understand interindividual differences in autobiographical memory specificity.
Beautiful stereotypes: the relationship between physical attractiveness and mixed race identity

The idea that mixed race individuals are physically attractive is a commonly accepted stereotype. Past research in which whites (Australians and British) and Asians (Japanese) were asked to rate the attractiveness of a racially heterogeneous group of faces has shown that mixed race phenotype was judged the most attractive. In this study, I examine whether there is empirical evidence for this Biracial Beauty Stereotype in the United States. Using the data from the National Longitudinal Survey of Adolescent Health, I examine self and interview ratings of respondents' physical attractiveness and, in an extension of the previous literature, conduct multinomial logistic regressions to ascertain whether level of attractiveness is associated with different racial identification choices for mixed race individuals. My results indicate that there is in fact a belief in mixed race individuals' superior beauty in America; but, with regard to identity, beauty is not associated with identity for all mixed race groups.
Rota virus genotypes and the clinical severity of Diarrhoea among children under 5 years of age

Background: Diarrhoeal disease still remains one of the common causes of morbidity and mortality in children under 5 years of age. It is caused notably by the different serotypes of rotavirus. Objectives: To ascertain the prevalence and risk factors for rotavirus diarrhoea in children under 5 years of age seen at Federal Medical Centre, Asaba, and to determine the different serotypes and their relationship with diarrhoea severity. Subjects and Methods: A hospital-based cross-sectional study in which all children under 5 years of age, with diarrhoea had their stool samples tested for rotavirus antigen with enzyme immunoassay. Significant values of variables were determined using t-tests and Chi-square tests as appropriate. Results: One hundred and thirty-two children were studied: 52.3% were males and 46.7% were females. Children 1-11 months of age constitute 49.2%, whereas those 12-59 months were 50.8%. Only 49 (37.1%) children were ELISA positive for rotavirus and of this number, 31 (63.3%) were within 1-11 months of age, P = 0.013. The three most common rotavirus genotypes were G3P[6] in 24.5%, G1P[6] in 12.2% and G12P[8] in 10.2% of the samples, respectively. Duration of vomiting was more prolonged with G3P[6] infection, P = 0.029, whereas dehydration and the overall severity of the diarrhoea were more with G12P[8] infection, P = 0.026 and 0.010, respectively. Conclusion: The emerging G12 rotavirus genotype was isolated in Asaba.
Provably Secure Networks: Methodology and Toolset for Configuration Management

Network administration is an inherently complex task, in particular with regard to security. Using the Isabelle interactive proof assistant, we develop two automated, formally verified tools which help uncovering and preventing bugs in network-level access control configurations. Our first tool guides the process of designing networks from scratch. Our second tool facilitates the analysis of existing iptables configurations. Combined, the two form a powerful toolset.
The impact of dictation practice on Turkish as a foreign language learners writing skills

The purpose of this study is to learn about the impact of dictation practice on B1 level Turkish as a foreign language learners’ writing skills. In this study, a pretest-posttest quasi-experimental design with control group was used. The study was carried out with 24 B1 level students enrolled in Gaziantep University Turkish and Foreign Languages Research and Application Center (TOMER). Both experimental and control groups consisted of 12 students. The data were analyzed by using both content analysis and descriptive statistics (frequency distribution). The results of the study revealed that students in experimental group made statistically significant gains in terms of word count (25%), vowel spelling mistakes (32%) and consonant spelling mistakes (44.5%). The results of the current study indicated that dictation practices have positive impacts on the ratios of students’ perceived word counts and their phonemic perceptions. In the light of these results, some practical recommendations and suggestions to improve TFL learners’ listening and writing skills were presented. Key words: Dictation, Teaching Turkish as a Foreign Language, writing skill.
Online Instrument Delivery and Participant Recruitment Services: Emerging Opportunities for Behavioral Accounting Research

ABSTRACT: Behavioral accounting researchers have historically been constrained in their ability to reach externally valid research participants. The purpose of this paper is to familiarize researchers with two relatively new and innovative ways to overcome this issue. First, this paper discusses two online instrument delivery services provided by SurveyMonkey and Qualtrics that can be used to distribute experimental materials to geographically distributed participants quickly and inexpensively. Second, it reviews a number of participant recruitment services that behavioral accounting researchers can use to identify and recruit externally valid research participants. Specifically, this paper discusses commercial participant recruitment services provided by SurveyMonkey Audience, Qualtrics, Amazon's Mechanical Turk, and other commercial firms, as well as several non-commercial participant recruitment services associated with industry and professional organizations. Each service is evaluated against three cr.
Design of two lightweight, high-bandwidth torque-controlled ankle exoskeletons

Lower-limb exoskeletons capable of comfortably applying high torques at high bandwidth can be used to probe the human neuromuscular system and assist gait. We designed and built two tethered ankle exoskeletons with strong lightweight frames, comfortable three-point contact with the leg, and series elastic elements for improved torque control. Both devices have low mass (<; 0.88 kg), are modular, structurally compliant in selected directions, and instrumented to measure joint angle and torque. The exoskeletons are actuated by an off-board motor, and torque is controlled using a combination of proportional feedback and damping injection with iterative learning during walking tests. We tested closed-loop torque control by commanding 50 N·m and 20 N·m linear chirps in desired torque while the exoskeletons were worn by human users, and measured bandwidths greater than 16 Hz and 21 Hz, respectively. During walking trials, we demonstrated 120 N·m peak torque and 2.0 N·m RMS torque tracking error. These performance measures compare favorably with existing devices and with human ankle musculature, and show that these exoskeletons can be used to rapidly explore a wide range of control techniques and robotic assistance paradigms as elements of versatile, high-performance testbeds. Our results also provide insights into desirable properties of lower-limb exoskeleton hardware, which we expect to inform future designs.
Patterns of work injuries: cases admitted to emergency room treatment compared to cases reported to the Danish Working Environment Authority during 2003–2010

Objective To compare work injuries treated in an emergency department (ED) and injuries reported to the Danish Working Environment Authority (DWEA). Methods Work injuries of the ED, Odense University Hospital, and injuries from the geographical catchment area reported to the DWEA between 2003 and 2010 were included. The injuries included in both datasets were identified by merging the ED file and the DWEA file using the civil registry number and injury date information as key. Results Approximately 50 000 work injuries occurred in the catchment area of the ED. The intersection between the two injury registration systems was 16%. A major discordance concerned the type of injuries, as some injuries were seen frequently in the ED but not reported to the DWEA to any significant extent, for example ‘eye injuries’ and ‘superficial lacerations or wounds’. On the other hand, some injuries are rarely seen in the ED, but often reported to the DWEA, for example ‘low back pain’. Additionally, younger workers visit the ED more often than older workers, and injuries in the high risk sectors have the lowest reporting proportion. Conclusions Neither the ED nor DWEA injury files alone give a complete picture of work injuries. But merged, they represent a significant number of injuries, taking into account differences in data sources, for example concerning uneven distribution of age, sex, type of injury and type of industry. Obviously, not all serious work related ED injuries resulting in lost work time are reported to the DWEA.
Cardiovascular Involvement in Autoimmune Diseases

Autoimmune diseases (AD) represent a broad spectrum of chronic conditions that may afflict specific target organs or multiple systems with a significant burden on quality of life. These conditions have common mechanisms including genetic and epigenetics factors, gender disparity, environmental triggers, pathophysiological abnormalities, and certain subphenotypes. Atherosclerosis (AT) was once considered to be a degenerative disease that was an inevitable consequence of aging. However, research in the last three decades has shown that AT is not degenerative or inevitable. It is an autoimmune-inflammatory disease associated with infectious and inflammatory factors characterized by lipoprotein metabolism alteration that leads to immune system activation with the consequent proliferation of smooth muscle cells, narrowing arteries, and atheroma formation. Both humoral and cellular immune mechanisms have been proposed to participate in the onset and progression of AT. Several risk factors, known as classic risk factors, have been described. Interestingly, the excessive cardiovascular events observed in patients with ADs are not fully explained by these factors. Several novel risk factors contribute to the development of premature vascular damage. In this review, we discuss our current understanding of how traditional and nontraditional risk factors contribute to pathogenesis of CVD in AD.
Learning process and learning outcomes of video podcasts including the instructor and PPT slides: a Chinese case

Video podcasts have become one of the fastest developing trends in learning and teaching. The study explored the effect of the presenting mode of educational video podcasts on the learning process and learning outcomes. Prior to viewing a video podcast, the 94 Chinese undergraduates participating in the study completed a demographic questionnaire and prior knowledge test. The learning process was investigated by eye-tracking and the learning outcome by a learning test. The results revealed that the participants using the video podcast with both the instructor and PPT slides gained the best learning outcomes. It was noted that they allocated much more visual attention to the instructor than to the PPT slides. It was additionally found that the 22 min was the time at which the participants reached the peak of mental fatigue. The results of our study imply that the use of educational technology is culture bound.
Is sleep-related attentional bias due to sleepiness or sleeplessness?

Sleep-related attentional bias is a well-documented finding in patients with primary insomnia. To address the question of whether attentional preference for sleep-related stimuli is due to sleepiness (as measured by the Stanford Sleepiness Scale; SSS) or sleeplessness (as measured by the Pittsburgh Sleep Quality Index; PSQI) we investigated 105 non-clinical participants with two attentional bias tasks, an emotional Stroop task and a newly introduced mixed-modality task. The emotional Stroop task revealed significant positive linear relationships between sleep-related attentional bias and both poor sleep quality and sleepiness. Additionally, we found a significant negative interaction effect between these two variables on the cognitive bias. This means that attentional bias scores are reduced when poor sleep quality is associated with high sleepiness and high sleep quality is associated with low sleepiness. We did not find any significant result in the mixed-modality task. The results suggest that sleep-related attentional bias can be elicited by both sleepiness and sleeplessness.