Miracle-dz/UniFAR-FTUs huggingface dataset:
The Authenticity Scale: Psychometric properties of a French translation and exploration of its relationships with personality and well-being.

In this article, we examined the psychometric properties of a French translation of the Authenticity Scale created by A. M. Wood, P. A. Linley, J. Maltby, M. Baliousis, and S. Joseph (2008, The authentic personality: A theoretical and empirical conceptualization and the development of the authenticity scale, Journal of Counseling Psychology, 55, 385–399). In the first study (N 188), we assessed the reliability of this translation as well as its construct validity and discriminant validity from the Big Five personality traits. In the second study (N 437), we conducted a confirmatory factor analysis to confirm the factorial structure found in Study 1 and the factorial structure obtained by Wood et al. (2008). The results show that the psychometric properties of the French Authenticity Scale are comparable to those of the original English version. The scale has both good scale score reliability ( .77 to .82) and temporal stability over an 8-week period (r .54 to .69). It is based on a three-factor solution explaining 60% of the variance. The scale shows discriminant validity from the Big Five personality traits and is related to both subjective and psychological well-being. This article provides a valid and reliable instrument in French that measures dispositional authenticity and will be useful to clinicians, counselors, and researchers.
Reishi or Ling Zhi (Ganoderma lucidum)

In Latin, lucidum means shiny or brilliant and aptly describes this mushroom’s fruiting body, which has a modeled, sculptured, varnished appearance. The Chinese and Koreans know it as Ling Zhi (mushroom of herb and immortality), whereas the Japanese call this mushroom reishi or mannentake (10,000 year mushroom). The virtues of G. lucidum extracts, handed down from generation to generation, include it as a ‘‘cancer cure’’ and a symbol of happy augury, good fortune, good health, longevity, and even immortality. Beginning with the Yuan Dynasty (1280–1368 A.D.), G. lucidum has been endlessly represented in art—in paintings, carvings of jade and deer’s antlers, furniture and carpet designs, balustrades, jewelry, women’s hair combs, perfume bottles—in short, wherever an artistic urge found an outlet. The earliest mention of Ling Zhi was in the era of the first emperor of China, Shinghuang of the Ch’in Dynasty (221–207 B.C.). Subsequently, depictions of this fungus proliferated through Chinese literature and art. The mushroom is known by many in North America and Europe as one of the ‘‘artist’s conk’’ fungi (the true artist conk is Ganoderma applanatum). A detailed description of the reishi mushroom and its taxonomy can be found in Refs. (Fig. 1).
Future Advances in COPD Therapy

There is a pressing need for more effective drug treatments for COPD. New bronchodilators include a long-acting anticholinergic tiotropium bromide and a dual β2-dopamine2-receptor agonist. But no treatments prevent the progression of COPD. Mediator antagonists in development include leukotriene B4 antagonists, chemokine receptor antagonists and more potent antioxidants. The inflammation of COPD is resistant to corticosteroids, so new anti-inflammatory drugs need to be developed. These include phosphodiesterase-4 inhibitors, nuclear factor-ĸB inhibitors and p38 MAP kinase inhibitors. Small molecule protease inhibitors, including neutrophil elastase inhibitors and selective matrix metalloproteinase inhibitors are also in development. Future drug targets may be identified by gene array and proteomics.
Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model

Bee venom has recently been suggested to possess beneficial effects in the treatment of Parkinson disease (PD). For instance, it has been observed that bilateral acupoint stimulation of lower hind limbs with bee venom was protective in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of PD. In particular, a specific component of bee venom, apamin, has previously been shown to have protective effects on dopaminergic neurons in vitro. However, no information regarding a potential protective action of apamin in animal models of PD is available to date. The specific goals of the present study were to (i) establish that the protective effect of bee venom for dopaminergic neurons is not restricted to acupoint stimulation, but can also be observed using a more conventional mode of administration and to (ii) demonstrate that apamin can mimic the protective effects of a bee venom treatment on dopaminergic neurons. Using the chronic mouse model of MPTP/probenecid, we show that bee venom provides sustained protection in an animal model that mimics the chronic degenerative process of PD. Apamin, however, reproduced these protective effects only partially, suggesting that other components of bee venom enhance the protective action of the peptide.
Postoperative Pain Management Using Intravenous Patient-Controlled Analgesia for Pediatric Patients

Pain control is an important consideration after any surgical procedures. Especially in children, more attention and care are needed during the period of postoperative pain control, which must be both sufficiently safe and effective. In this respect, intravenous patient-controlled analgesia provides improved titration of analgesic drugs, thereby maintaining optimal analgesic status with few side effects. Thirty pediatric patients were randomly divided into two groups: the intravenous patient-controlled analgesia group (with nalbuphine HCl and ketorolac tromethamine) and the conventional pethidine HCl intramuscular group. The degree of analgesia was assessed every 4 hours until the second postoperative day. The intravenous patient-controlled analgesia group had significantly lower pain scores and took less time until they were able to walk to the bathroom, but as many side effects as the control group. We concluded that intravenous patient-controlled analgesia is safe and effective for pediatric patients who have moderate to severe pain after operations such as rib cartilage graft, iliac bone graft, and large flap surgeries.
Smartphones and Cognition: A Review of Research Exploring the Links between Mobile Technology Habits and Cognitive Functioning

While smartphones and related mobile technologies are recognized as flexible and powerful tools that, when used prudently, can augment human cognition, there is also a growing perception that habitual involvement with these devices may have a negative and lasting impact on users’ ability to think, remember, pay attention, and regulate emotion. The present review considers an intensifying, though still limited, area of research exploring the potential cognitive impacts of smartphone-related habits, and seeks to determine in which domains of functioning there is accruing evidence of a significant relationship between smartphone technology and cognitive performance, and in which domains the scientific literature is not yet mature enough to endorse any firm conclusions. We focus our review primarily on three facets of cognition that are clearly implicated in public discourse regarding the impacts of mobile technology – attention, memory, and delay of gratification – and then consider evidence regarding the broader relationships between smartphone habits and everyday cognitive functioning. Along the way, we highlight compelling findings, discuss limitations with respect to empirical methodology and interpretation, and offer suggestions for how the field might progress toward a more coherent and robust area of scientific inquiry.
Randomized, Placebo-Controlled Trial of Green Tea Catechins for Prostate Cancer Prevention

Preclinical, epidemiologic, and prior clinical trial data suggest that green tea catechins (GTC) may reduce prostate cancer risk. We conducted a placebo-controlled, randomized clinical trial of Polyphenon E (PolyE), a proprietary mixture of GTCs, containing 400 mg (−)-epigallocatechin-3-gallate (EGCG) per day, in 97 men with high-grade prostatic intraepithelial neoplasia (HGPIN) and/or atypical small acinar proliferation (ASAP). The primary study endpoint was a comparison of the cumulative one-year prostate cancer rates on the two study arms. No differences in the number of prostate cancer cases were observed: 5 of 49 (PolyE) versus 9 of 48 (placebo), P = 0.25. A secondary endpoint comparing the cumulative rate of prostate cancer plus ASAP among men with HGPIN without ASAP at baseline, revealed a decrease in this composite endpoint: 3 of 26 (PolyE) versus 10 of 25 (placebo), P < 0.024. This finding was driven by a decrease in ASAP diagnoses on the Poly E (0/26) compared with the placebo arm (5/25). A decrease in serum prostate-specific antigen (PSA) was observed on the PolyE arm [−0.87 ng/mL; 95% confidence intervals (CI), −1.66 to −0.09]. Adverse events related to the study agent did not significantly differ between the two study groups. Daily intake of a standardized, decaffeinated catechin mixture containing 400 mg EGCG per day for 1 year accumulated in plasma and was well tolerated but did not reduce the likelihood of prostate cancer in men with baseline HGPIN or ASAP. Cancer Prev Res; 8(10); 879–87. ©2015 AACR.
Motivations To Produce User Generated Content: Differences Between Webloggers And Videobloggers

This explorational study seeks to elucidate the question of what motivates weblogger and videoblogger to produce user generated content. Particular focus was laid on the question whether motivational differences can be discerned between webloggers and video producers and why people do not produce content. The findings show that it is the intrinsic motivations that are responsible for today’s user generated content. Video producers and webloggers differ in their motivations. Video production is more associated with fun and time passing than is weblogging. Weblogging is regarded as being more useful in the dissemination of information. The main reasons for not producing content are opportunity costs and privacy issues.
INFLUENCE OF GLOBAL CLIMATE CHANGE ON CHEMICAL FATE AND BIOACCUMULATION: THE ROLE OF MULTIMEDIA MODELS

Multimedia environmental fate models are valuable tools for investigating potential changes associated with global climate change, particularly because thermodynamic forcing on partitioning behavior as well as diffusive and nondiffusive exchange processes are implicitly considered. Similarly, food‐web bioaccumulation models are capable of integrating the net effect of changes associated with factors such as temperature, growth rates, feeding preferences, and partitioning behavior on bioaccumulation potential. For the climate change scenarios considered in the present study, such tools indicate that alterations to exposure concentrations are typically within a factor of 2 of the baseline output. Based on an appreciation for the uncertainty in model parameters and baseline output, the authors recommend caution when interpreting or speculating on the relative importance of global climate change with respect to how changes caused by it will influence chemical fate and bioavailability. Environ. Toxicol. Chem. 2013;32:20–31. © 2012 SETAC
Negotiating leave in the workplace: Leave practices and masculinity constructions among Danish fathers

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Automatic Synthesis of Large Telescopic Units Based on Near-Minimum Timed Supersetting

In high-performance systems, variable-latency units are often employed to improve the average throughput when the worst-case delay exceeds the cycle time. Traditionally, units of this type have been hand-designed. In this paper, we propose a technique for the automatic synthesis of variable-latency units that is applicable to large data-path modules. We define and study an optimization problem, timed supersetting, whose solution is at the kernel of the procedure for automatic generation of variable-latency units. We contribute a new algorithm for solving timed supersetting in the most difficult case, that is, when the timing behavior of the circuit is expressed through an accurate delay model. The proposed solution overcomes the computational limitations of previous approaches and its robustness is experimentally demonstrated by obtaining high-throughput, variable-latency implementations for all the largest circuits in the Iscas '85 and Iscas '89 benchmark suites, as well as for some realistic, high-performance arithmetic units.
Is Alzheimer disease related to age-related macular degeneration?

BACKGROUND/AIM To compare the cognitive functions and define the frequency of Alzheimer disease (AD) between participants with and without age-related macular degeneration (AMD). MATERIALS AND METHODS Fifty-nine patients with late-stage AMD (74.3 ± 7.3 years) and 49 age-, sex-, and education-matched control subjects were compared for the presence of AD according to the guidelines of the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA). Detailed neuropsychological tests were performed for all subjects. RESULTS Neuropsychiatric tests scores were lower in the AMD group than the control group. The frequency of AD was higher in patients with AMD (40.7% in AMD and 20.4% in control group, P = 0.03), and particularly higher in late dry (nonvascular) AMD (d-AMD) patients (71.4% in d-AMD and 31.1% in late wet (vascular) AMD, P = 0.007). d-AMD patients performed worse than controls on all tests. There was also an association between age, sex, and low education and neuropsychiatric tests scores (P < 0.01). However, there was no association between visual acuity and neuropsychiatric tests scores. CONCLUSION The increased frequency of AD in patients with AMD is significant. This study demonstrated the importance of cognitive assessment in patients with AMD, particularly in the d-AMD type.
Cancers of upper gingivobuccal sulcus, hard palate and maxilla: A tertiary care centre study in North India

Introduction: Oral cancer is the sixth most common malignancy in the world, and the third most common in southeast Asia. Cancers of the upper gingivo-buccal complex are uncommon and reported infrequently. In this article, we have assessed the clinicopathological features of such cancers and their optimal management. Materials and Methods: We studied 64 patients with cancer of the upper gingivobuccal sulcus (GBS), hard palate, and maxilla seen between February 2009 and 2013 over a span of 4 years. Results: Of the 64 patients studied, 45 were male. The mean age at presentation was 50.59 years (24-80 years). Of the 64, 48 patients (75%) had a history of substance abuse in the form of tobacco chewing, smoking or alcohol. On presentation, 48 of the 64 patients (75%) had T4 disease, eight had T3, six had T2 lesion, one had T1 lesion, and 1 patient had a neck recurrence with distant metastatic disease (Tx). Out of the 64 patients, 31 had clinically palpable neck disease and two patients had distant metastatic disease. Of the 64 patients, 58 had squamous cell carcinoma, two had adenoid cystic carcinoma of the hard palate and one patient each had melanoma, sarcoma, neuroendocrine tumor, and mucoepidermoid carcinoma. Following imaging, 18 patients (28.13%) underwent upfront surgery and six following neoadjuvant chemotherapy. 14 of the 24 patients operated had simultaneous neck dissection. 2 patients with distant metastasis and 1 with cavernous sinus thrombosis received palliative chemotherapy. Out of the 64 patients, the other 24 who were inoperable were referred to radiotherapy. Conclusion: Upper GBS, hard palate and maxilla cancers are uncommon and are diagnosed at an advanced stage due to delay in presentation and ignorance of our population. Surgery offers the best form of treatment. NACT may be tried to downstage the disease in selected patients with borderline operable disease. However, generous margins should be taken post chemotherapy with concomitant neck dissection. Adjuvant radiotherapy is recommended in selected patients after surgery.
Serum cholesterol, haemorrhagic stroke, ischaemic stroke, and myocardial infarction: Korean national health system prospective cohort study

Abstract Objective To investigate risk factors, such as heavy alcohol consumption, that might explain any increased risk of haemorrhagic stroke associated with low blood cholesterol. Design Prospective cohort study. Setting Korea. Participants 787 442 civil servants (661 700 men, 125 742 women) aged 30-64. Main outcome measures Cardiovascular risk factors were assessed at biennial health check. Data on morbidity and mortality were ascertained from 1990 to 2001 using hospital admissions and mortality surveillance systems. Results 6328 cases of ischaemic stroke (6021 men, 307 women), 3947 cases of haemorrhagic stroke (3748 men, 199 women), 3170 cases of undefined stroke (2902 men, 268 women), and 4417 cases of myocardial infarction (4305 men, 112 women) occurred. Ischaemic stroke and myocardial infarction were strongly and positively associated with blood cholesterol (hazard ratio per 1 mmol/l cholesterol 1.20 (95% confidence 1.16 to 1.24) and 1.48 (1.43 to 1.53), respectively). Haemorrhagic stroke showed an inverse association in fully adjusted models (0.91, 0.87 to 0.95). This inverse association was confined to participants with hypertension. When stratified by concentration of γ glutamyl transferase (GGT), an indicator of alcohol consumption, the association was not seen in participants with low concentrations of GGT, and it was independent of hypertension in those with high concentrations of GGT (> 80 U/l). Conclusion High alcohol consumption may underlie the association between low blood cholesterol and increased risk of haemorrhagic stroke.
The national healthcare system claims databases in France, SNIIRAM and EGB: Powerful tools for pharmacoepidemiology

The French health care system is based on universal coverage by one of several health care insurance plans. The SNIIRAM database merges anonymous information of reimbursed claims from all these plans, linked to the national hospital‐discharge summaries database system (PMSI) and the national death registry. It now covers 98.8% of the French population, over 66 million persons, from birth (or immigration) to death (or emigration), making it possibly the world's largest continuous homogeneous claims database. The database includes demographic data; health care encounters such as physician or paramedical visits, medicines, medical devices, and lab tests (without results); chronic medical conditions (ICD10 codes); hospitalisations with ICD10 codes for primary, linked and associated diagnoses, date and duration, procedures, diagnostic‐related groups, and cost coding; date but currently not cause of death. The power of the database is correlatively great, and its representativeness is near perfect, since it essentially includes the whole country's population. The main difficulty in using the database, beyond its sheer size and complexity, is the administrative process necessary to access it. Recent legislative advances are making this easier.
Impaired planning in Parkinson's disease is reflected by reduced brain activation and connectivity

Parkinson's disease (PD) often entails impairments of executive functions, such as planning. Although widely held that these impairments arise from dopaminergic denervation of the striatum, not all executive functions are affected early on, and the underlying neural dynamics are not fully understood. In a combined longitudinal and cross‐sectional study, we investigated how planning deficits progress over time in the early stages of PD compared to matched healthy controls. We used functional magnetic resonance imaging (fMRI) to identify accompanying neural dynamics.
Energy efficiency analysis of small cell networks

Small cell networks have recently been proposed as an important evolution path for the next-generation cellular networks. While such approach has the potential of meeting the growing network throughput requirement, the energy efficiency of small cell networks is of great concern as the base station (BS) density will be significantly increased. The objective of this paper is to analyze the energy efficiency in small cell networks. To do so, we adopt a random spatial network model, where BSs and users are modeled as two independent spatial Poisson point processes (PPPs). We shall derive analytical results for the network energy efficiency, which show that the BS power consumption model plays a critical role. In particular, it will be shown that increasing the BS density can actually improve the energy efficiency if the BS power consumption that is not related to signal transmission is less than a certain threshold. By comparing the cases between single-antenna and multi-antenna BSs, we find that single-antenna BSs provide a higher energy efficiency if the circuit power is larger than a threshold. Simulation results will demonstrate that our conclusions which are based on the random network model also hold in a regular grid-based model.
Subgroup Analysis via Recursive Partitioning

Subgroup analysis is an integral part of comparative analysis where assessing the treatment effect on a response is of central interest. Its goal is to determine the heterogeneity of the treatment effect across subpopulations. In this paper, we adapt the idea of recursive partitioning and introduce an interaction tree (IT) procedure to conduct subgroup analysis. The IT procedure automatically facilitates a number of objectively defined subgroups, in some of which the treatment effect is found prominent while in others the treatment has a negligible or even negative effect. The standard CART (Breiman et al., 1984) methodology is inherited to construct the tree structure. Also, in order to extract factors that contribute to the heterogeneity of the treatment effect, variable importance measure is made available via random forests of the interaction trees. Both simulated experiments and analysis of census wage data are presented for illustration.
Electrocardiogram Provides a Continuous Heart Rate Faster Than Oximetry During Neonatal Resuscitation

OBJECTIVE: To compare the time required to obtain a continuous audible heart rate signal from an electrocardiogram (ECG) monitor and pulse oximeter (PO) in infants requiring resuscitation. METHODS: Infants who had both ECG and PO placed during resuscitation were analyzed using video and analog recordings. The median times from arrival until the ECG electrodes and PO sensor were placed, and the time to achieve audible tones from the devices, were compared. RESULTS: Forty-six infants had ECG and PO data. Thirty infants were very low birth weight (23–30 weeks). There was a difference in the median total time to place either device (26 vs 38 seconds; P = .04), and a difference (P < .001) in the time to achieve an audible heart rate signal after ECG lead (2 seconds) versus PO probe (24 seconds) placement. In infants weighing >1500 g (n = 16), the median time (interquartile range) to place the ECG was 20 seconds (14–43) whereas the time to place the PO was 36 seconds (28–56) (P = .74). The median times (interquartile range) to acquire a signal from the ECG and PO were 4 seconds (1–6) and 32 seconds (15–40, P = .001), respectively. During the first minutes of resuscitation, 93% of infants had an ECG heart rate compared with only 56% for PO. CONCLUSIONS: Early application of ECG electrodes during infant resuscitation can provide the resuscitation team with a continuous audible heart rate, and its use may improve the timeliness of appropriate critical interventions.