Miracle-dz/UniFAR-FTUs huggingface dataset:
Distributed Space-Time Trellis Code for Asynchronous MIMO Relays over Frequency-Selective Channels

In most cooperative communications works, perfect synchronization among relay nodes is assumed. However, this assumption is not realistic due to the distributed nature of each relay node. In this paper, we consider the downlink in a MIMO cellular network utilizing two-hop transmission protocols with fixed infrastructure relay stations (RS) to enhance coverage and data rates. We propose a family of distributed space-time trellis code (DSTTC) for two RSs without the synchronization assumption. It is shown that the construction of the proposed DSTTCs is equivalent to using the generator matrices that have full row rank regardless of sub-matrices shifting problem, where a sub-matrix corresponds to the generator matrix of a RS under frequency-selective channels. Finally, various numerical examples are provided to verify the analytical studies.
Optimism Following a Tornado Disaster

Effects of exposure to a severe weather disaster on perceived future vulnerability were assessed in college students, local residents contacted through random-digit dialing, and community residents of affected versus unaffected neighborhoods. Students and community residents reported being less vulnerable than their peers at 1 month, 6 months, and 1 year after the disaster. In Studies 1 and 2, absolute risk estimates were more optimistic with time, whereas comparative vulnerability was stable. Residents of affected neighborhoods (Study 3), surprisingly, reported less comparative vulnerability and lower “gut-level” numerical likelihood estimates at 6 months, but later their estimates resembled the unaffected residents. Likelihood estimates (10%-12%), however, exceeded the 1% risk calculated by storm experts, and gut-level versus statistical-level estimates were more optimistic. Although people believed they had approximately a 1-in-10 chance of injury from future tornadoes (i.e., an overestimate), they thought their risk was lower than peers.
Normative data for regional sweat sodium concentration and whole-body sweating rate in athletes

Abstract The purpose of this study was to establish normative data for regional sweat sodium concentration ([Na+]) and whole-body sweating rate in athletes. Data from 506 athletes (367 adults, 139 youth; 404 male, 102 female) were compiled from observational athlete testing for a retrospective analysis. The participants were skill/team-sport (including American football, baseball, basketball, soccer and tennis) and endurance (including cycling, running and triathlon) athletes exercising in cool to hot environmental conditions (15–50°C) during training or competition in the laboratory or field. A standardised regional absorbent patch technique was used to determine sweat [Na+] on the dorsal mid-forearm. Whole-body sweat [Na+] was predicted using a published regression equation (y = 0.57x+11.05). Whole-body sweating rate was calculated from pre- to post-exercise change in body mass, corrected for fluid/food intake (ad libitum) and urine output. Data are expressed as mean ± SD (range). Forearm sweat [Na+] and predicted whole-body sweat [Na+] were 43.6 ± 18.2 (12.6–104.8) mmol · L–1 and 35.9 ± 10.4 (18.2–70.8) mmol · L–1, respectively. Absolute and relative whole-body sweating rates were 1.21 ± 0.68 (0.26–5.73) L · h–1 and 15.3 ± 6.8 (3.3–69.7) ml · kg–1 · h–1, respectively. This retrospective analysis provides normative data for athletes’ forearm and predicted whole-body sweat [Na+] as well as absolute and relative whole-body sweating rate across a range of sports and environmental conditions.
Epidemiology of Mycoplasma genitalium in British men and women aged 16–44 years: evidence from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)

Background: There are currently no large general population epidemiological studies of Mycoplasma genitalium (MG), which include prevalence, risk factors, symptoms and co-infection in men and women across a broad age range. Methods: In 2010-–12, we conducted the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3), a probability sample survey in Britain. Urine from 4507 sexually-experienced participants, aged 16–44 years, was tested for MG. Results: MG prevalence was 1.2% [95% confidence interval (CI): 0.7–1.8%] in men and 1.3% (0.9–1.9%) in women. There were no positive MG tests in men aged 16–19, and prevalence peaked at 2.1% (1.2–3.7%) in men aged 25–34 years. In women, prevalence was highest in 16–19 year olds, at 2.4% (1.2–4.8%), and decreased with age. Men of Black ethnicity were more likely to test positive for MG [adjusted odds ratio (AOR) 12.1; 95% CI: 3.7–39.4). For both men and women, MG was strongly associated with reporting sexual risk behaviours (increasing number of total and new partners, and unsafe sex, in the past year). Women with MG were more likely to report post-coital bleeding (AOR 5.8; 95%CI 1.4–23.3). However, the majority of men (94.4%), and over half of women (56.2%) with MG did not report any sexually transmitted infection (STI) symptoms. Men with MG were more likely to report previously diagnosed gonorrhoea, syphilis or non-specific urethritis, and women previous trichomoniasis. Conclusions: This study strengthens evidence that MG is an STI. MG was identified in over 1% of the population, including in men with high-risk behaviours in older age groups that are often not included in STI prevention measures.
Capitalization of R&D and the Informativeness of Stock Prices

Abstract This paper presents both a new approach to studying the consequences of accounting choice and a unique sample to examine the effects of accounting choice in the R&D context. We investigate the effect of firms' decision to capitalize R&D expenditures on the amount of information about future earnings reflected in current stock returns, as captured by the association between current-year returns and future earnings (FERC). We use a sample of UK firms, which includes both R&D capitalizers and expensers. An important feature of our tests is our use of a two-equation system to control for the endogeneity of the accounting choice (i.e. self-selection). Proponents of capitalization claim that it enables management to better communicate information about the success of projects and their probable future benefits. Consistent with this, we find that capitalization is associated with higher FERC than expensing.
Conservative and Surgical Treatment of Clubfoot

One hundred twenty-four patients (174 feet) were treated for clubfoot deformity, with an average follow-up of 7 years. All patients were initially treated by manipulation and serial casting. Early soft tissue surgeries were performed for resistant cases (73 feet). In 33 feet with residual hindfoot deformity only, posterior release was performed with 85% good results. In the remainder, where there was forefoot as well as hindfoot deformity, full posteromedial release was necessary, giving good results in 90% of cases. All clubfeet should initially be treated conservatively. However, resistant cases should have early surgery, with the extent of surgery performed being determined by the type of residual deformity present.
Genome-Wide Expression and Location Analyses of the Candida albicans Tac1p Regulon

ABSTRACT A major mechanism of azole resistance in Candida albicans is overexpression of the genes encoding the ATP binding cassette transporters Cdr1p and Cdr2p due to gain-of-function mutations in Tac1p, a transcription factor of the zinc cluster family. To identify the Tac1p regulon, we analyzed four matched sets of clinical isolates representing the development of CDR1- and CDR2-mediated azole resistance by using gene expression profiling. We identified 31 genes that were consistently up-regulated with CDR1 and CDR2, including TAC1 itself, and 12 consistently down-regulated genes. When a resistant strain deleted for TAC1 was examined similarly, expression of almost all of these genes returned to levels similar to those in the matched azole-susceptible isolate. Using genome-wide location (ChIP-chip) analysis (a procedure combining chromatin immunoprecipitation with hybridization to DNA intergenic microarrays), we found 37 genes whose promoters were bound by Tac1p in vivo, including CDR1 and CDR2. Sequence analysis identified nine new genes whose promoters contain the previously reported Tac1p drug-responsive element (CGGN4CGG), including TAC1. In total, there were eight genes whose expression was modulated in the four azole-resistant clinical isolates in a TAC1-dependent manner and whose promoters were bound by Tac1p, qualifying them as direct Tac1p targets: CDR1, CDR2, GPX1 (putative glutathione peroxidase), LCB4 (putative sphingosine kinase), RTA3 (putative phospholipid flippase), and orf19.1887 (putative lipase), as well as IFU5 and orf19.4898 of unknown function. Our results show that Tac1p binds under nonactivating conditions to the promoters of its targets, including to its own promoter. They also suggest roles for Tac1p in regulating lipid metabolism (mobilization and trafficking) and oxidative stress response in C. albicans.
Image Prediction for Limited-angle Tomography via Deep Learning with Convolutional Neural Network

Limited angle problem is a challenging issue in x-ray computed tomography (CT) field. Iterative reconstruction methods that utilize the additional prior can suppress artifacts and improve image quality, but unfortunately require increased computation time. An interesting way is to restrain the artifacts in the images reconstructed from the practical filtered back projection (FBP) method. Frikel and Quinto have proved that the streak artifacts in FBP results could be characterized. It indicates that the artifacts created by FBP method have specific and similar characteristics in a stationary limited-angle scanning configuration. Based on this understanding, this work aims at developing a method to extract and suppress specific artifacts of FBP reconstructions for limited-angle tomography. A data-driven learning-based method is proposed based on a deep convolutional neural network. An end-to-end mapping between the FBP and artifact-free images is learned and the implicit features involving artifacts will be extracted and suppressed via nonlinear mapping. The qualitative and quantitative evaluations of experimental results indicate that the proposed method show a stable and prospective performance on artifacts reduction and detail recovery for limited angle tomography. The presented strategy provides a simple and efficient approach for improving image quality of the reconstruction results from limited projection data.
Clinical Significance of Trochlear Calcifications in the Orbit

BACKGROUND AND PURPOSE: Trochlear calcification is frequently seen on CT scans that include the orbits, but prior studies linking this finding to diabetes mellitus were based on selected populations by using relatively thick sections. We assessed the relationship between trochlear calcification and diabetes mellitus and other chronic medical conditions in an unrestricted population by using thin-section CT. MATERIALS AND METHODS: Noncontrast head CT studies performed consecutively on 1000 patients between January and February 2011 were retrospectively reviewed for the presence of trochlear calcifications. Axial 1.25-mm-thick images acquired by 64-detector row CT were reviewed. Medical records were reviewed for chronic medical conditions, including diabetes mellitus, chronic kidney disease, alcoholism, autoimmune conditions, endocrine disorders, serum calcium and alkaline phosphatase levels, and HIV status. Motion-limited studies and patients with limited clinical data were excluded. Statistical analyses were performed by using the Fisher exact test. RESULTS: Thirty-two patients were excluded from analysis. Of the remaining 968 patients, 128 had trochlear calcification (13%). No significant association was observed between diabetes mellitus and trochlear calcifications in patients of any age (P = .40). There was no significant correlation between trochlear calcifications and chronic kidney disease, alcoholism, endocrine disorders, or HIV infection. Statistically significant associations among trochlear calcification, autoimmune conditions, and elevated alkaline phosphatase levels were observed (P < .0001 and P < .0001, respectively). CONCLUSIONS: On the basis of a large unrestricted population with thin-section CT imaging of the orbit, no significant association was observed between trochlear calcifications and diabetes mellitus. A statistically significant association was observed between trochlear calcification and autoimmune disease and elevated alkaline phosphatase levels.
Healthy weight control and dissonance-based eating disorder prevention programs: results from a controlled trial.

OBJECTIVE Because universal psychoeducational eating disorder prevention programs have had little success, we developed and evaluated two interventions for high-risk populations: a healthy weight control intervention and a dissonance-based intervention. METHOD Adolescent girls (N = 148) with body image concerns were randomized to one of these interventions or to a waitlist control group. Participants completed baseline, termination, and 1, 3, and 6-month follow-up surveys. RESULTS Participants in both interventions reported decreased thin-ideal internalization, negative affect, and bulimic symptoms at termination and follow-up relative to controls. However, no effects were observed for body dissatisfaction or dieting and effects diminished over time. DISCUSSION Results provide evidence that both interventions effectively reduce bulimic pathology and risk factors for eating disturbances.
Possible Evidence for Variation in Magnitude for Marsquakes From Fallen Boulder Populations, Grjota Valles, Mars

Following observations of mobilized boulder trail populations from Cerberus Fossae, Mars, that have been interpreted as possible evidence of large‐magnitude marsquakes rupturing for distances of ~207 km along exposed active faults, additional boulder trail populations were measured along shorter faults within the region of Grjota Valles (50‐ to 150‐km length) to test the hypotheses that (1) these faults are also candidate locations for marsquakes and (2) that marsquake magnitude might be smaller, limited by fault dimensions available for rupture. For a region containing two en echelon graben, boulder trail data define two anomalies with maxima in (a) boulder trails per kilometer and (b) maximum width of boulder trails, one that is ~116 km in length along strike and the other ~70 km in length along strike. Values for the maxima are 45 trails per kilometer and 5‐m mean trail width for the 70‐km‐long anomaly and 115 trails per kilometer with 5.3‐m mean trail width for the 116‐km‐long anomaly, above background values measured elsewhere along these faults of zero trails per kilometer with zero boulder trail widths. If combined with published data from Cerberus Fossae with an ~207‐km‐long anomaly in boulder trails per km (125 trails per kilometer maxima) and maximum mean boulder trail width (8.5‐m maximum trail width), the three data sets suggest correlations between the (a) along‐strike length of boulder trail anomalies, (b) boulder trails per kilometer, and (c) maximum boulder trail width. If interpreted as due to single marsquakes, and if the dimensions of these anomalies are a proxy for rupture length, when combined, one interpretation of this is that boulders have been mobilized by marsquakes and that the marsquake magnitude is proportional to the along‐strike length of the anomalies. In other words, the data suggest that marsquake magnitude, if that is the cause of the anomalies, is limited by fault length as expected for terrestrial seismically active faults. Such findings suggest that the Martian surface may have been shaken, in the very recent past, by large‐magnitude marsquakes. We discuss this in terms of the seismicity of Mars.
Nonlinear Kalman Filtering With Divergence Minimization

We consider the nonlinear Kalman filtering problem using Kullback–Leibler (KL) and <inline-formula> <tex-math notation="LaTeX">$\alpha$</tex-math></inline-formula>-divergence measures as optimization criteria. Unlike linear Kalman filters, nonlinear Kalman filters do not have closed form Gaussian posteriors because of a lack of conjugacy due to the nonlinearity in the likelihood. In this paper, we propose novel algorithms to approximate this posterior by optimizing the forward and reverse forms of the KL divergence, as well as the <inline-formula> <tex-math notation="LaTeX">$\alpha$</tex-math></inline-formula>-divergence that contains these two as limiting cases. Unlike previous approaches, our algorithms do not make approximations to the divergences being optimized, but use Monte Carlo techniques to derive unbiased algorithms for direct optimization. We assess performance on radar and sensor tracking, and options pricing, showing general improvement over the extended, unscented, and ensemble Kalman filters, as well as competitive performance with particle filtering.
A novel mutation in the ATP1A2 gene causes alternating hemiplegia of childhood

Alternating hemiplegia of childhood (AHC, MIM 104290) is a rare syndrome, characterised by early onset of episodic hemi- or quadriplegia lasting minutes to days. This disorder, first reported by Verret and Steel in 1971,1 has historically been thought to represent a migraine equivalent1 or an unusual form of epilepsy or a movement disorder,2 as it typically presents with complex and variable clinical features. In most patients, the earliest manifestations clearly related to AHC are tonic–dystonic attacks and paroxysmal nystagmus associated with autonomic changes and paroxysmal dyspnoea and usually appear between 3 and 6 months of age. The hemiplegic episodes develop before 18 months of age lasting anywhere from minutes to days at a time and involving either side of the body or shifting from one side to the other during the same episode with a period of bilateral weakness when the second side becomes involved.3 Some attacks are characterised by a bilateral involvement, which is apparent from the beginning, and do not follow an hemiplegic episode,3 which determines extreme hypotonia of the whole body with inability to move and a level of consciousness markedly depressed. A characteristic feature of AHC is the disappearance of all abnormalities when the child falls asleep.3 With increasing age, hemiplegic episodes follow a general pattern of initially increasing frequency and duration, followed by a plateau, and finally by a decrease in the number and duration of attacks. Analogously, the paroxysmal manifestations associated with hemiplegia tend to decrease in frequency and intensity with time and usually disappear after 5–7 years. Development before the onset of hemiplegic episodes may be normal or delayed. Epileptic seizures are reported in a variable percentage of sporadic patients.3–5 An association with migraine has also been noticed since the earliest description.1 Indeed, for …
Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast

Background An excess of caffeine is cytotoxic to all eukaryotic cell types. We aim to study how cells become tolerant to a toxic dose of this drug, and the relationship between caffeine and oxidative stress pathways. Methodology/Principal Findings We searched for Schizosaccharomyces pombe mutants with inhibited growth on caffeine-containing plates. We screened a collection of 2,700 haploid mutant cells, of which 98 were sensitive to caffeine. The genes mutated in these sensitive clones were involved in a number of cellular roles including the H2O2-induced Pap1 and Sty1 stress pathways, the integrity and calcineurin pathways, cell morphology and chromatin remodeling. We have investigated the role of the oxidative stress pathways in sensing and promoting survival to caffeine. The Pap1 and the Sty1 pathways are both required for normal tolerance to caffeine, but only the Sty1 pathway is activated by the drug. Cells lacking Pap1 are sensitive to caffeine due to the decreased expression of the efflux pump Hba2. Indeed, ? hba2 cells are sensitive to caffeine, and constitutive activation of the Pap1 pathway enhances resistance to caffeine in an Hba2-dependent manner. Conclusions/Significance With our caffeine-sensitive, genome-wide screen of an S. pombe deletion collection, we have demonstrated the importance of some oxidative stress pathway components on wild-type tolerance to the drug.
Development of Fetal Yawn Compared with Non-Yawn Mouth Openings from 24–36 Weeks Gestation

Background Although some research suggests that fetuses yawn, others disagree arguing that is it simple mouth opening. Furthermore there is no developmental account of fetal yawning compared with simple mouth opening. The aim of the present study was to establish in a repeated measures design the development of fetal yawning compared with simple mouth opening. Methodology/Findings Video recordings were made of the fetal face and upper torso visualized by means of 4D full frontal or facial profile ultrasound recordings. Fifteen healthy fetuses were scanned four times at 24, 28, 32 and 36 weeks gestation. Yawning was distinguished from non-yawning in terms of the length of time it took to reach the apex of the mouth stretch, with yawns being defined as more than 50% of the total time observed. To assess changes in frequency, a Poisson mixed effects model was fitted to the count of number of yawn and simple mouth opening events with age and gender as fixed effects, and person as a random effect. For both yawns and simple mouth openings a smooth varying age effect was significant. The number of yawns observed declined with age from 28 weeks gestation, whereas simple mouth openings were less frequent and the decline was observed from 24 weeks. Gender was not significant either for yawn and simple mouth openings. Conclusions/Significance Yawning can be reliably distinguished from other forms of mouth opening with the potential of using yawning as an index of fetal healthy development.