Miracle-dz/UniFAR-FTUs huggingface dataset:
Pilates Exercises Influence on the Serotonin Hormone, Some Physical Variables and the Depression Degree in Battered Women

2 Abstract: The purpose of the study is to identify the Pilates exercises program impact on the serotonin hormone and some physical variables which represented in the (legs and back muscles strength, muscular endurance and flexibility) and the depression degree for battered women. 10 Ladies of the resident in the host and guide institute of the battered women of Minia governorate were subjected to implement the Pilates exercises program for 12 weeks. The researchers used experimental method by pre and post measurement design to one group, using Beck Aaron measure to measure depression degree and statistical data indicated that there are statistically significant differences between pre and post measurements favoring post measurements in th e variables under consideration and for the telemetric and the presence of correlation inverse between the serotonin hormone and the depression degree, it was extracted that Pilates exercise have a positive impact on reduction of the depression degree, improvement in muscle strength, muscular endurance and flexibility.
Unsupervised monaural speech enhancement using robust NMF with low-rank and sparse constraints

Non-negative spectrogram decomposition and its variants have been extensively investigated for speech enhancement due to their efficiency in extracting perceptually meaningful components from mixtures. Usually, these approaches are implemented on the condition that training samples for one or more sources are available beforehand. However, in many real-world scenarios, it is always impossible for conducting any prior training. To solve this problem, we proposed an approach which directly extracts the representations of background noises from the noisy speech via imposing non-negative constraints on the low-rank and sparse decomposition of the noisy spectrogram. The noise representations are subsequently utilized when estimating the clean speech. In this technique, potential spectral structural regularity could be discovered for better reconstruction of clean speech. Evaluations on the Noisex-92 and TIMIT database showed that the proposed method achieves significant improvements over the state-of-the-art methods in unsupervised speech enhancement.
Deriving relations from the experimental analysis of behavior.

Reviewing a basic research study inJEAB and then trying to relate aspects of the methods and results to applied work appears to involve comparing a sample stimulus to a variety of comparison stimuli. In this instance, the sample stimulus (information in JEAB) for the dinician or applied investigator is less familiar and more novel than the comparison stimuli (dinical and applied problems). The task of the applied behavior analyst is to discern from among the comparison stimuli which best matches, is relevant, and shares equivalent relations with the sample. Whether the relational responding anticipated by this series, "Developments in Basic Research and Their Potential Application," will combine with direct contingencies (e.g., Hayes & Hayes, 1993, p. 507) has yet to be demonstrated. But, perhaps, by considering developments in basic research, methods for enhancing both correct matching and contingency contacting can be identified so as to advance the cause of relating basic and applied research. Three previous artides in this series share some common features. Each has described recentJEAB artides in a manner far less technical than the original version. A second common feature is that other artides in this series appear to have a theme. Themes ranged from "Convergence" (Hineline & Wacker, 1993), to "Collateral Effects" (Shull & Fuqua, 1993), to "The Applied Importance of Relational Responding" (Hayes & Hayes, 1993). In this regard we shall be no different. The theme for this artide will be "Language Is Behavior" (Catania,
Mutations in the diastrophic dysplasia sulfate transporter (DTDST) gene (SLC26A2): 22 novel mutations, mutation review, associated skeletal phenotypes, and diagnostic relevance

Mutations in the DTDST gene can result in a family of skeletal dysplasia conditions which comprise two lethal disorders, achondrogenesis type 1B (ACG1B) and atelosteogenesis type 2 (AO2); and two non‐lethal disorders, diastrophic dysplasia (DTD) and recessive multiple epiphyseal dysplasia (rMED). The gene product is a sulfate‐chloride exchanger of the cell membrane. Inactivation of the sulfate exchanger leads to intracellular sulfate depletion and to the synthesis of undersulfated proteoglycans in susceptible cells such as chondrocytes and fibroblasts. Genotype–phenotype correlations are recognizable, with mutations predicting a truncated protein or a non‐conservative amino acid substitution in a transmembrane domain giving the severe phenotypes, and non‐transmembrane amino acid substitutions and splice site mutations giving the milder phenotypes. The clinical phenotype is modulated strictly by the degree of residual activity. Over 30 mutations have been observed, including 22 novel mutations reported here. The most frequent mutation, 862C>T (R279W), is a mild mutation giving the rMED phenotype when homozygous and mostly DTD when compounded; occurrence at a CpG dinucleotide and its panethnic distribution suggest independent recurrence. Mutation IVS1+2T>C is the second most common mutation, but is very frequent in Finland. It produces low levels of correctly spliced mRNA, and results in DTD when homozygous. Two other mutations, 1045‐1047delGTT (V340del) and 558C>T (R178X), are associated with severe phenotypes and have been observed in multiple patients. Most other mutations are rare. Heterozygotes are clinically unaffected. When clinical samples are screened for radiologic and histologic features compatible with the ACG1B/AO2/DTD/rMED spectrum prior to analysis, the mutation detection rate is high (over 90% of alleles), and appropriate genetic counseling can be given. The sulfate uptake or sulfate incorporation assays in cultured fibroblasts have largely been replaced by mutation analysis, but may still be useful in cases where mutation analysis is not informative. Although supplementation of patients’ cultured cells with thiols may bypass the transporter defect and enhance sulfation of proteoglycans, therapeutic approaches are not yet available. Mouse models for this and other disorders of sulfate metabolism are being developed to help in developing therapeutic treatments. Hum Mutat 17:159–171, 2001. © 2001 Wiley‐Liss, Inc.
Challenge Test Results in Patients With Suspected Penicillin Allergy, but No Specific IgE

Purpose Patients with a history of allergic reaction to penicillin, but with no detectable specific IgE, are common and pose a dilemma. Challenge tests are considered to be the diagnostic gold standard. The aim of this study was to identify subgroups of patients with very low risk for reactions who could be safely tested using a more rapid and simple procedure. Methods A total of 580 consecutively referred adult patients with a history of non-serious cutaneous allergic reactions to penicillin, but with no IgE, were challenged with therapeutic doses of penicillin V (phenoxymethylpenicillin), penicillin G (benzylpenicillin), or both. Results Only 14 of 580 patients had a positive challenge test. In 11 of the 14, a reaction to challenge occurred within 2 hours, and none were anaphylactic. The year of the original reaction was known for 555 patients; a positive challenge was seen in only 0.4% of those with an original reaction >15 years before challenge, but in 4.6% of those with a more recent original reaction (P=0.001). Onset of a reaction within the first day of the original exposure was a predictive factor for a positive challenge (P=0.001) in patients challenged within 15 years of the original reaction. Conclusions Among suspected penicillin-allergic patients with non-severe skin reactions and no detectable specific IgE, the subgroup of patients who originally reacted more than 15 years previously had very low risk for reacting to a challenge. The risk was higher in patients with a more recent original reaction, especially if the symptoms had occurred within the first day of exposure.
An Advanced Press Review System Combining Deep News Analysis and Machine Learning Algorithms

In our media-driven world the perception of companies and institutions in the media is of major importance. The creation of press reviews analyzing the media response to company-related events is a complex and time-consuming task. In this demo we present a system that combines advanced text mining and machine learning approaches in an extensible press review system. The system collects documents from heterogeneous sources and enriches the documents applying different mining, filtering, classification, and aggregation algorithms. We present a system tailored to the needs of the press department of a major German University. We explain how the different components have been trained and evaluated. The system enables us demonstrating the live analyzes of news and social media streams as well as the strengths of advanced text mining algorithms for creating a comprehensive media analysis.
Italian Political Parties on the Web

To draw some conclusions about the implications of parties' engagement with the new information and communications technologies (ICTs) for the quality of democracy, this article explores the way in which Italian parties are exploiting the World Wide Web for campaigning and related functions. Italy has been chosen because it is a liberal democracy and yet has party-system and other characteristics in terms of which it differs from other democracies that have been used to explore the political implications of use of the new ICTs. Adding an Italian case study to the existing work consequently allows us to move closer to an understanding of the conditions under which the new ICTs will have an impact. Defining the quality of democracy in terms of the degree to which parties and individual citizens are afforded equality of influence in political decision making, this research points in the direction of a muted impact because of a tendency of the parties to use the new medium to carry out existing campaign tasks more efficiently and effectively rather than seek to use it in innovative ways. However, this same tendency may improve the quality of democracy in another sense, namely, by reinvigorating and strengthening the party organizations that are central to the representative process in the first place.
They will not even give me a cup of water: Stress and coping among women living with HIV in Southern India

Limited research has examined the mental health of women living with HIV and AIDS in low and middle income countries such as India. This exploratory study examined distress and coping among twenty HIV positive women in rural southern India. Focus groups were conducted in Tamil, and coded for thematic content. Women were asked about hardships, support from the community, and preferred forms of coping. Several themes emerged including: social and familial rejection; difficulty meeting basic needs; concerns for the future of children; and interest in helping others in similar circumstances. Participants highlighted the importance of medication adherence and social support in maintaining physical and mental wellbeing. Future research should investigate these themes in a larger sample of HIV positive women in the region using mixed methods. Intervention strategies should also be explored to reduce HIV stigma, and increase community acceptance and social support for individuals struggling with HIV-related social exclusion. Key words: HIV and AIDS, India, mental health, women, stigma, coping.
COLI ISOLATED FROM THE STOOLS OF CHILDREN AGED 0-10 YEARS WITH DIARRHEA IN MID-ANATOLIA REGION

The stool samples from 245 patients with diarrhea were tested for heat labile toxin (LT) and heat stable toxins (ST) by passive latex agglutination and enzyme immunoassay methods respectively. Twelve (4.9%) enterotoxigenic E. Coli ETEC strains were isolated. Five strains (2%) expressed ST, and 7 (2.8%) expressed LT.
Psychological appraisal in temporomandibular disorders: A cross-sectional study

Aims and Objectives: The objective of this study was to investigate the prevalence of stress and depression within temporomandibular disorder (TMD) patient subgroups with chronic facial pain (cfp) and healthy controls and to assess possible relationships among the different subgroups. It also evaluated the correlation among pain, stress, and depression scores. Materials and Methods: A total number of 120 patients, 60 cases and 60 controls aged 20-40 years were included in the study. The study group after clinical examination was assigned into subgroups depending on the Research Diagnostic Criteria for TMD (RDC/TMD). Age- and sex-matched patients with no complaints of TMD formed the control group. Both the groups were administered the Beck′s inventory of depression (BDI) and stress symptom rating scale (SSRS) questionnaires. Pain intensity was measured by the visual analogue scale. All the scores were statistically analyzed. Results: Depression and stress scores were seen more in the myofascial pain group. Depression was prevalent in 53.3% and stress in 60% of the study group. Positive correlation was seen among pain scores, depression, and stress scores (P < .001). Conclusion: The findings are consistent with previous research indicating a link among depression, stress, and TMD. Screening for such symptoms should be an integral part of the evaluation for effective cognitive behavioural therapy.
PRIVACY PROTECTION STRATEGIES ON FACEBOOK

The privacy paradox describes people's willingness to disclose personal information on social network sites despite expressing high levels of concern. In this study, we employ the distinction between institutional and social privacy to examine this phenomenon. We investigate what strategies undergraduate students have developed, and their motivations for using specific strategies. We employed a mixed-methods approach that included 77 surveys and 21 in-depth interviews. The results suggest that, in addition to using the default privacy settings, students have developed a number of strategies to address their privacy needs. These strategies are used primarily to guard against social privacy threats and consist of excluding contact information, using the limited profile option, untagging and removing photographs, and limiting Friendship requests from strangers. Privacy strategies are geared toward managing the Facebook profile, which we argue functions as a front stage. This active profile management allows users to negotiate the need for connecting on Facebook with the desire for increased privacy. Thus, users disclose information, because they have made a conscious effort to protect themselves against potential violations. We conclude that there is a tilt toward social privacy concerns. Little concern was raised about institutional privacy and no strategies were in place to protect against threats from the use of personal data by institutions. This is relevant for policy discussions, because it suggests that the collection, aggregation, and utilization of personal data for targeted advertisement have become an accepted social norm.
Adherence to Antipsychotic Medication in Bipolar Disorder and Schizophrenic Patients

Abstract Antipsychotics are the drugs prescribed to treat psychotic disorders; however, patients often fail to adhere to their treatment, and this has a severe negative effect on prognosis in these kinds of illnesses. Among the wide range of risk factors for treatment nonadherence, this systematic review covers those that are most important from the point of view of clinicians and patients and proposes guidelines for addressing them. Analyzing 38 studies conducted in a total of 51,796 patients, including patients with schizophrenia spectrum disorders and bipolar disorder, we found that younger age, substance abuse, poor insight, cognitive impairments, low level of education, minority ethnicity, poor therapeutic alliance, experience of barriers to care, high intensity of delusional symptoms and suspiciousness, and low socioeconomic status are the main risk factors for medication nonadherence in both types of disorder. In the future, prospective studies should be conducted on the use of personalized patient-tailored treatments, taking into account risk factors that may affect each individual, to assess the ability of such approaches to improve adherence and hence prognosis in these patients.
Phase I study of temozolomide in children and adolescents with recurrent solid tumors: a report from the Children's Cancer Group.

PURPOSE The Children's Cancer Group conducted a phase I trial of temozolomide stratified by prior craniospinal irradiation (CSI). PATIENTS AND METHODS Children and adolescents with recurrent or progressive cancer were enrolled. Temozolomide was administered orally daily for 5 days, with subsequent courses administered every 21 to 28 days after full hematologic recovery. Dose levels tested included 100, 150, 180, 215, 245, and 260 mg/m2 daily. RESULTS Twenty-seven patients on the non-CSI stratum were assessable for hematologic toxicity. During the first three dose levels (100, 150, and 180 mg/m2 daily), only grades 1 and 2 hematologic toxicity occurred. One patient at 215 mg/m2 daily had grade 3 hematologic toxicity. Three of eight patients (38%) treated at 245 to 260 mg/m2 daily had dose-limiting toxicity (DLT), which included both neutropenia and thrombocytopenia. Twenty-two patients on the CSI stratum were assessable for hematologic toxicity. Hematologic DLT occurred in one of six patients (17%) at 100 mg/m2 daily and in two of four patients (50%) at 215 mg/m2 daily. No nonhematologic DLT occurred; nausea and vomiting occurred in more than half of the patients. After two courses of temozolomide, 10 patients had stable disease (SD), and three patients had a partial response (PR), one of whom subsequently had a complete response (CR) that persists through 24 months of follow-up. CONCLUSION The maximum-tolerated dose (MTD) of temozolomide for children and adolescents without prior CSI is 215 mg/m2 daily and for those with prior CSI is 180 mg/m2 daily for 5 days, with subsequent courses that begin on day 28. Temozolomide is well tolerated and should undergo phase II testing in children and adolescents.
Classifying Personalization Constraints in Digital Business Environments through Case Study Research

To aid professionals in the early assessment of possible risks related to personalization activities in marketing as well as to give academics a starting point to discover not only the opportunities but also the risks of personalization, a ‘Classification Scheme of Personalization Constraints’ is established after the analysis of 24 case studies. The classification scheme includes three dimensions: origin (internal, external), subject (technological, organizational) and time (data collection, matchmaking, delivery) and describes the different obstacles with which companies are confronted when implementing personalization activities. Additionally four ‘Standard Types of Personalization Environments’ are developed. They describe a set of business environments which inherit different internal and external risks related to personalization activities in marketing. The standard types are termed Flow, Performance, Dependence and Risk.
A realist synthesis of controlled studies to determine the effectiveness of interventions to prevent genital cutting of girls

Abstract Background: Female genital mutilation/cutting (FGM/C) is a traditional practice which involves the partial or total removal or other injury to the female genital organs for non-medical reasons. Although current trends indicate that the practice is becoming less prevalent, as many as 30 million girls may still be at risk of FGM/C. Given the associated risks and violation of the human rights of girls and women, the practice is discouraged through preventative interventions. Aims: To systematically review the effectiveness of anti-FGM/C interventions, applying a realist perspective. Methods: The realist synthesis approach addressed context-mechanisms-outcomes (CMO) underlying intervention in an attempt to explain interventions’ success or lack thereof. The process involved exposed the usefulness of strategies in different contexts. Results: Eight effectiveness studies and 27 context studies were included. All of the effectiveness studies employed a controlled, before-and-after study design. They formed five broad categories of intervention: training, formal classroom education, media communication, outreach and advocacy, and informal adult education. The CMO configurations showed that the proposed engine behind changing behaviours regarding FGM/C appeared largely to be dissemination of information. Some interventions’ acceptability and success rested on the incorporation of FGM/C abandonment efforts within a larger set of related issues. However, greater success of the interventions could have materialised with systematic pre-planning involving thorough community analyses and securing religious leaders’ commitment to halting FGM/C. Conclusion: The results of this analysis point to conditions that facilitate the success of FGM/C abandonment programmes in different contexts and can be used in future prevention efforts to reduce the risk of girls being subjected to FGM/C.
THE ROLE OF THE LYMPHATIC SYSTEM IN THE REJECTION OF HOMOGRAFTS: A STUDY OF LYMPH FROM RENAL TRANSPLANTS

The rejection of renal homografts has been studied in sheep by transplanting kidneys into the neck and preserving the renal lymphatic drainage intact. Chronic fistulae were established in the transplanted renal lymphatics and lymph collected throughout the life of the graft. The changes that occurred in homografts during the process of rejection were reflected in changes in the lymph. Large numbers of basophilic, blast, lymphoid cells appeared in the lymph, and lymph production in the grafted kidney increased 20–50 fold. Over a period of about 10 days, up to 60 g wet weight of lymphoid cells and up to 10 liters of lymph were collected from the graft. Within 24 hr of grafting, the host cells present in the renal lymph had become sensitized to the graft and transformed into blast cells when cultivated in Millipore chambers in vitro. When the cells leaving the graft during the first 18–48 hr were injected into distant nonstimulated lymph nodes of the host sheep, they evoked significant cellular and antibody responses in the nodes. Within the graft, the main pathological changes were found in the vascular endothelium and many of the peritubular capillaries become plugged with emboli comprised of blast cells. There was extensive infiltration of the renal parenchyma with lymphoid cells and evidence of their transformation and proliferation within the renal blood capillaries. When all the lymph and cells leaving the homograft were diverted from the body, there was a greatly decreased reaction in the regional prescapular lymph node, and no reaction in lymph nodes distant from the graft. In these circumstances, the survival of the graft was not prolonged, and it was rejected without involvement of the lymph nodes of the host. Humoral antibody was produced in the lymph node regional to the homograft within 48–60 hr of grafting. Antibody was not detected in the blood or in the renal lymph until near to the time the graft was rejected. It was thought that this was due to the binding of antibody by the kidney graft tissue. We conclude that all the events which lead to the recognition and rejection of renal homografts can occur centrally within the graft itself.