Miracle-dz/UniFAR-FTUs huggingface dataset:
Laser-based segment classification using a mixture of bag-of-words

In this paper, we propose a segment-based object detection approach using laser range data. Our detection approach is built up of three stages: First, a hierarchical segmentation approach generates a hierarchy of coarse-to-fine segments to reduce the impact of over- and under-segmentation in later stages. Next, we employ a learned mixture model to classify all segments. The model combines multiple softmax regression classifiers learned on specific bag-of-word representations using different parameterizations of a descriptor. In the final stage, we filter irrelevant and duplicate detections using a greedy method in consideration of the segment hierarchy. We experimentally evaluate our approach on recently published real-world datasets to detect pedestrians, cars, and cyclists.
Least-squares and minimum chi-square estimation in a discrete Weibull model

ABSTRACT In this work, we investigate the properties of least-squares and minimum chi-square methods for the point estimation of the two parameters characterizing a discrete Weibull distribution. The first method, inflected into three variants, is based on the empirical cumulative distribution function and provides a closed analytical expression for each estimate. The second method is based on the minimization of the well-known chi-square statistic, which provides a numerical solution. A Monte Carlo simulation study empirically assesses the performance of the methods; two applications on real data show how the inferential techniques practically work.
Iterative-refinement for action timing discretization

Artificial Intelligence search algorithms search discrete systems. To apply such algorithms to continuous systems, such systems must first be discretized, i.e. approximated as discrete systems. Action-based discretization requires that both action parameters and action timing be discretized. We focus on the problem of action timing discretization.After describing an ε-admissible variant of Korf's recursive best-first search (ε-RBFS), we introduce iterative-refinement ε-admissible recursive best-first search (IR ε-RBFS) which offers significantly better performance for initial time delays between search states over several orders of magnitude. Lack of knowledge of a good time discretization is compensated for by knowledge of a suitable solution cost upper bound.
Cryptogenic organizing pneumonia: CT findings in 43 patients.

OBJECTIVE Description of the CT findings of cryptogenic organizing pneumonia has been limited to a small number of cases. This study was performed to characterize the CT findings of this disease in a larger number of cases and to compare the findings in immunocompetent and immunocompromised patients. MATERIALS AND METHODS The CT scans of 43 (32 immunocompetent and 11 immunocompromised) patients who had biopsy-proved cryptogenic organizing pneumonia were reviewed. The scans were obtained by using contiguous 8- or 10-mm collimation and selected thin (1.5 or 2.0 mm) section (n = 23), thin-section collimation at 10-mm intervals (n = 12), or 8- or 10-mm collimation only (n = 8). The scans were analyzed by three observers, and final decisions were reached by consensus. RESULTS The most common pattern seen was consolidation, which was present alone or as part of a mixed pattern in 34 cases (79%). The consolidation had a predominantly subpleural and/or peribronchovascular distribution in 27 cases (63%). Ground-glass attenuation and nodules were seen in 26 patients (60%) and 13 patients (30%), respectively, and were usually random in distribution. Consolidation was present in 91% (29/32) of immunocompetent and 45% (5/11) of immunocompromised patients (p < .01). Ground-glass attenuation was present in 56% (18/32) of immunocompetent and 73% (8/11) of immunocompromised patients (p > .25). Nodules were present in seven (22%) of 32 immunocompetent patients and six (55%) of 11 immunocompromised patients (p < .025). CONCLUSION We conclude that in immunocompetent patients the CT findings in cryptogenic organizing pneumonia most commonly consist of bilateral areas of consolidation involving mainly the subpleural and/or peribronchovascular regions. In the immunocompromised patient, the CT findings are variable.
Web-based Intervention to Promote Physical Activity by Sedentary Older Adults: Randomized Controlled Trial

Background Physical activity (PA) for older adults has well-documented physical and cognitive benefits, but most seniors do not meet recommended guidelines for PA, and interventions are lacking. Objectives This study evaluated the efficacy of a 12-week Internet intervention to help sedentary older adults over 55 years of age adopt and maintain an exercise regimen. Methods A total of 368 sedentary men and women (M=60.3; SD 4.9) were recruited, screened, and assessed online. They were randomized into treatment and control groups and assessed at pretest, at 12 weeks, and at 6 months. After treatment group participants rated their fitness level, activity goals, and barriers to exercise, the Internet intervention program helped them select exercise activities in the areas of endurance, flexibility, strengthening, and balance enhancement. They returned to the program weekly for automated video and text support and education, with the option to change or increase their exercise plan. The program also included ongoing problem solving to overcome user-identified barriers to exercise. Results The multivariate model indicated significant treatment effects at posttest (P=.001; large effect size) and at 6 months (P=.001; medium effect size). At posttest, intervention participation showed significant improvement on 13 of 14 outcome measures compared to the control participants. At 6 months, treatment participants maintained large gains compared to the control participants on all 14 outcome measures. Conclusions These results suggest that an online PA program has the potential to positively impact the physical activity of sedentary older adult participants. More research is needed to replicate the study results, which were based on self-report measures. Research is also needed on intervention effects with older populations.
Natural transmission of foot-and-mouth disease virus between African buffalo (Syncerus caffer) and impala (Aepyceros melampus) in the Kruger National Park, South Africa

VP1 gene sequences of SAT-2 type foot-and-mouth disease (FMD) viruses recovered from impala and African buffalo in the Kruger National Park (KNP) were used to determine intra- and interspecies relationships of viruses circulating in these wildlife populations. On this basis five distinct lineages of SAT-2 virus were identified in routine sampling of oesophageo-pharyngeal epithelium from buffalo between 1988 and 1996. Different lineages were associated with discrete geographic sampling localities. Over the period 1985–95, four unrelated epizootics occurred in impala in defined localities within the KNP. Evidence for natural transmission of FMD between buffalo and impala is presented for the most recent 1995 outbreak, with data linking the 1985 and 1988/9 impala epizootics to viruses associated with specific buffalo herds.
Effects of Thrombin on Neurogenesis After Intracerebral Hemorrhage

Background and Purposes— Neurogenesis in intracerebral hemorrhage (ICH) has not been investigated. Thrombin formation causes acute brain injury after ICH, but thrombin also can stimulate cell proliferation. The present study examined whether neurogenesis takes place in ICH and the role of thrombin in ICH-related neurogenesis. Methods— This study was divided into four parts. (1) Rats received either an ICH or a needle insertion (sham). The rats were killed for doublecortin (DCX) Western blot analysis and immunohistochemistry. (2) Rats had an ICH or a sham operation, and then received intraperitoneal injections of 5-bromo-2′-deoxyuridine (BrdU) at day-7 and day-9 later. Brains were perfused to identify BrdU-positive cells. (3) Rats had an intracaudate injection of thrombin (1 U) and brains were sampled for Western blots. (4) Rats had an ICH with or without a thrombin inhibitor, hirudin. The brains were sampled for DCX quantitation. Results— DCX levels in the ipsilateral basal ganglia started to increase as early as 7 days after ICH, peaked at 14 days, and then gradually decreased at 1 month. Immunohistochemistry also demonstrated that DCX immunoreactivity was increased in the ipsilateral subventricular zone and basal ganglia at 2 weeks after ICH. Some DCX-positive cells were BrdU-positive. One unit thrombin, which does not cause marked brain injury, was injected into the caudate. Thrombin increased DCX levels in the ipsilateral basal ganglia and hirudin blocked ICH-induced upregulation of DCX. Conclusions— Our results demonstrated that neurogenesis occurs in the brain after ICH and that thrombin may play a role in ICH-induced neurogenesis.
Identifiability of Generalized Randles Circuit Models

The Randles circuit (including a parallel resistor and capacitor in series with another resistor) and its generalized topology have widely been employed in electrochemical energy storage systems, such as batteries, fuel cells, and supercapacitors, also in biomedical engineering, for example, to model the electrode–tissue interface in electroencephalography and baroreceptor dynamics. This paper studies identifiability of generalized Randles circuit models, that is, whether the model parameters can be estimated uniquely from the input–output data. It is shown that generalized Randles circuit models are structurally locally identifiable. The condition that makes the model structure globally identifiable is then discussed. Finally, the estimation accuracy with respect to noise-free, noisy, zero-mean, and nonzero-mean data is evaluated through extensive simulations. The existing tradeoff between the estimation of Warburg term and other parameters by using zero- and nonzero-mean data is fully discussed.
Comparison and combination of several MeSH indexing approaches

MeSH indexing of MEDLINE is becoming a more difficult task for the group of highly qualified indexing staff at the US National Library of Medicine, due to the large yearly growth of MEDLINE and the increasing size of MeSH. Since 2002, this task has been assisted by the Medical Text Indexer or MTI program. We extend previous machine learning analysis by adding a more diverse set of MeSH headings targeting examples where MTI has been shown to perform poorly. Machine learning algorithms exceed MTI's performance on MeSH headings that are used very frequently and headings for which the indexing frequency is very low. We find that when we combine the MTI suggestions and the prediction of the learning algorithms, the performance improves compared to any single method for most of the evaluated MeSH headings.
A Relational Extension of the Notion of Motifs: Application to the Common 3D Protein Substructures Searching Problem

The geometrical configurations of atoms in protein structures can be viewed as approximate relations among them. Then, finding similar common substructures within a set of protein structures belongs to a new class of problems that generalizes that of finding repeated motifs. The novelty lies in the addition of constraints on the motifs in terms of relations that must hold between pairs of positions of the motifs. We will hence denote them as relational motifs. For this class of problems, we present an algorithm that is a suitable extension of the KMR paradigm and, in particular, of the KMRC as it uses a degenerate alphabet. Our algorithm contains several improvements that become especially useful when-as it is required for relational motifs-the inference is made by partially overlapping shorter motifs, rather than concatenating them. The efficiency, correctness and completeness of the algorithm is ensured by several non-trivial properties that are proven in this paper. The algorithm has been applied in the important field of protein common 3D substructure searching. The methods implemented have been tested on several examples of protein families such as serine proteases, globins and cytochromes P450 additionally. The detected motifs have been compared to those found by multiple structural alignments methods.
Healing through Histidine: Bioinspired Pathways to Self-Healing Polymers via Imidazole–Metal Coordination

Biology offers a valuable inspiration toward the development of self-healing engineering composites and polymers. In particular, chemical level design principles extracted from proteinaceous biopolymers, especially the mussel byssus, provide inspiration for design of autonomous and intrinsic healing in synthetic polymers. The mussel byssus is an acellular tissue comprised of extremely tough protein-based fibers, produced by mussels to secure attachment on rocky surfaces. Threads exhibit self-healing response following an apparent plastic yield event, recovering initial material properties in a time-dependent fashion. Recent biochemical analysis of the structure–function relationships defining this response reveal a key role of sacrificial cross-links based on metal coordination bonds between Zn2+ ions and histidine amino acid residues. Inspired by this example, many research groups have developed self-healing polymeric materials based on histidine (imidazole)–metal chemistry. In this review, we provide a detailed overview of the current understanding of the self-healing mechanism in byssal threads, and an overview of the current state of the art in histidine- and imidazole-based synthetic polymers.
Inhibition of Ribonucleotide Reductase Reduces Neointimal Formation following Balloon Injury

Percutaneous transluminal coronary angioplasty (PTCA) has greatly benefited patients with occluded coronary arteries, but its benefits have been undermined by a high incidence of restenosis. The introduction of coronary stents has significantly improved the short and long term outcome but restenosis still occurs in approximately 15 to 30% of patients within 6 months. Research efforts are now being directed toward combination stenting and drug delivery. Among the therapeutic targets being pursued are agents that can impede smooth muscle cell migration and proliferation, as these processes are critical components of restenosis injury. We propose that inhibiting the conversion of ribonucleotides to deoxyribonucleotides will impede cell proliferation and, as such, limit the degree of restenosis. Therefore, we tested whether the potent ribonucleotide reductase inhibitors Didox (3,4-dihydroxybenzohydraxamic acid) and Imidate (ethyl-3,4,5-hydroxybenzimidate) can limit the neointimal proliferation associated with restenosis using a rat carotid model of balloon dilatation injury. Results demonstrated that both Didox and Imidate significantly reduced intimal thickening, resulting in a 71 and 62% decrease in the intima/media ratio, respectively. Similar efficacy was seen with the commercially available ribonucleotide reductase inhibitor hydroxyurea, demonstrating the importance of this enzyme in vascular remodeling. Results from cell proliferation studies suggest that the mechanism of protection is inhibition of smooth muscle cell (SMC) proliferation. In addition, Didox and Imidate (100 μM) are potent inhibitors of SMC migration, which may also contribute to their vascular protective effects. These results suggest that inhibition of ribonucleotide reductase may provide a potent strategy to prevent post-PTCA restenosis.
Preliminary Assessment of Health Risks of Potentially Toxic Elements in Settled Dust over Beijing Urban Area

To examine levels, health risks, sources, and spatial distributions of potentially toxic elements in settled dust over Beijing urban area, 62 samples were collected mostly from residential building outdoor surfaces, and their <63 μm fractions were measured for 12 potentially toxic elements. The results show that V, Cr, Mn, Co, Ni, and Ba in dust are from predominantly natural sources, whereas Cu, Zn, As, Cd, Sb, and Pb mostly originate from anthropogenic sources. Exposure to these elements in dust has significant non-cancer risks to children but insignificant to adults. Cancer risks of Cr, Co, Ni, As, and Cd via inhalation and dermal contact are below the threshold of 10−6–10−4 but As via dust ingestion shows a tolerable risk. The non-cancer risks to children are contributed mainly (75%) by As, Pb, and Sb, and dominantly (92%) via dust ingestion, with relatively higher risks mainly occurring in the eastern and northeastern Beijing urban areas. Although Cd, Zn, and Cu in dust are heavily affected by anthropogenic sources, their health risks are insignificant. Source appointments suggest that coal burning emissions, the dominant source of As, are likely the largest contributors to the health risk, and traffic-related and industrial emissions are also important because they contribute most of the Pb and Sb in dust.
Overview of the INLI PAN at FIRE-2017 Track on Indian Native Language Identification

This overview paper describes the first shared task on Indian Native Language Identification (INLI) that was organized at FIRE 2017. Given a corpus with comments in English from various Facebook newspapers pages, the objective of the task is to identify the native language among the following six Indian languages: Bengali, Hindi, Kannada, Malayalam, Tamil, and Telugu. Altogether, 26 approaches of 13 different teams are evaluated. In this paper, we give an overview of the approaches and discuss the results that they have obtained.
Accuracy of a 10 Hz GPS Unit in Measuring Shuttle Velocity Performed at Different Speeds and Distances (5 – 20 M)

Abstract The aim of this study was to validate the accuracy of a 10 Hz GPS device (STATSports, Ireland) by comparing the instantaneous values of velocity determined with this device with those determined by kinematic (video) analysis (25 Hz). Ten male soccer players were required to perform shuttle runs (with 180° change of direction) at three velocities (slow: 2.2 m·s-1; moderate: 3.2 m·s-1; high: maximal) over four distances: 5, 10, 15 and 20 m. The experiments were video-recorded; the “point by point” values of speed recorded by the GPS device were manually downloaded and analysed in the same way as the “frame by frame” values of horizontal speed as obtained by video analysis. The obtained results indicated that shuttle distance was smaller in GPS than video analysis (p < 0.01). Shuttle velocity (shuttle distance/shuttle time) was thus smaller in GPS than in video analysis (p < 0.001); the percentage difference (bias, %) in shuttle velocity between methods was found to decrease with the distance covered (5 m: 9 ± 6%; 20 m: 3 ± 3%). The instantaneous values of speed were averaged; from these data and from data of shuttle time, the distance covered was recalculated; the error (criterion distance-recalculated distance) was negligible for video data (0.04 ± 0.28 m) whereas GPS data underestimated criterion distance (0.31 ± 0.55 m). In conclusion, the inaccuracy of this GPS unit in determining shuttle speed can be attributed to inaccuracy in determining the shuttle distance.
Variations in lipid profile during fasting in Ramazan in healthy male adults.

Ramazan fasting, one of the pillars of Islam, extends from dawn until sunset. In high northern latitudes, depending on month oftheyear, period of fasting can be longer. During this period individuals abstain from eating, drinking, oral medication, intravenous fluids and nutrients. The calorie gap during fasting is usually bridged by taking extra milk, sweets, fried snacks and dates. The physiological and biochemical effects of fasting are mild and reversible. This paper describes the effect of Ramazan fasting on serum lipids profile in healthy adult males.
Heterogeneity in the expression and subcellular localization of POLYOL/MONOSACCHARIDE TRANSPORTER genes in Lotus japonicus

Polyols can serve as a means for the translocation of carbon skeletons and energy between source and sink organs as well as being osmoprotective solutes and antioxidants which may be involved in the resistance of some plants to biotic and abiotic stresses. Polyol/Monosaccharide transporter (PLT) proteins previously identified in plants are involved in the loading of polyols into the phloem and are reported to be located in the plasma membrane. The functions of PLT proteins in leguminous plants are not yet clear. In this study, a total of 14 putative PLT genes (LjPLT1-14) were identified in the genome of Lotus japonicus and divided into 4 clades based on phylogenetic analysis. Different patterns of expression of LjPLT genes in various tissues were validated by qRT-PCR analysis. Four genes (LjPLT3, 4, 11, and 14) from clade II were expressed at much higher levels in nodule than in other tissues. Moreover, three of these genes (LjPLT3, 4, and 14) showed significantly increased expression in roots after inoculation with Mesorhizobium loti. Three genes (LjPLT1, 3, and 9) responded when salinity and/or osmotic stresses were applied to L. japonicus. Transient expression of GFP-LjPLT fusion constructs in Arabidopsis and Nicotiana benthamiana protoplasts indicated that the LjPLT1, LjPLT6 and LjPLT7 proteins are localized to the plasma membrane, but LjPLT2 (clade IV), LjPLT3, 4, 5 (clade II) and LjPLT8 (clade III) proteins possibly reside in the Golgi apparatus. The results suggest that members of the LjPLT gene family may be involved in different biological processes, several of which may potentially play roles in nodulation in this nitrogen-fixing legume.
Timing Decisions in Organizations: Communication and Authority in a Dynamic Environment

We consider a problem where an uninformed principal makes a timing decision interacting with an informed but biased agent. Because time is irreversible, the direction of the bias crucially affects the agent's ability to credibly communicate information. When the agent favors late decision making, full information revelation often occurs. In this case, centralized decision making, where the principal retains authority and communicates with the agent, implements the optimal decision-making rule. When the agent favors early decision making, communication is partial, and the optimal decision-making rule is not implemented. Delegation adds value when the bias is for early decision making, but not for late decision making.
Tropical sea surface temperature, vertical wind shear, and hurricane development

The anomalously strong hurricane activity in the Atlantic sector during the recent years led to a controversy about the impact of global warming on hurricane activity in the Atlantic sector. Here we show that the temperature difference between the tropical North Atlantic and the tropical Indian and Pacific Oceans (Indo‐Pacific) is a key parameter in controlling the vertical wind shear over the Atlantic, an important quantity for hurricane activity. The stronger warming of the tropical North Atlantic relative to that of the Indo‐Pacific during the most recent years drove reduced vertical wind shear over the Atlantic and is thus responsible for the strong hurricane activity observed. In 2006, however, the temperature difference between the tropical North Atlantic and the tropical Indian and Pacific Oceans is much reduced, which explains the relatively weak hurricane season.