Miracle-dz/UniFAR-FTUs huggingface dataset:
Bridging the Gap: Evidence from ERPs on the Processing of Unbounded Dependencies

Since the early days of generative grammar, the study of unbounded dependencies such as wh-questions and relative clauses has occupied a central place in both syntactic theory and language processing research. The problem that such constructions pose is as follows. In a normal wh-question, a wh-phrase is typically displaced to the left periphery of a clause (What did you say to John? ); this displaced constituent is often referred to as a filler. The vacant position (indicated in the previous example by a blank line) where it would ordinarily occur in an echo question (You said what to John? ) is correspondingly referred to as a gap. Filler and gap are mutually dependent on each other since they share syntactic and semantic information essential for successful sentence interpretation. However, since sentence processing is a sequential operation, a filler cannot be assigned to its gap until some time after it has occurred. In other words, the filler must be held in working memory until such time as filler-gap assignment can take place. The intent of the research reported here was to examine the processing of unbounded dependencies in English as revealed in event-related brain potentials (ERPs). To this end, subjects were shown both grammatical and ungrammatical yes/no-questions (Did you say something to John? ) and wh-questions. A number of comparisons made at various points in these questions showed that both the storage of a filler in working memory and its subsequent retrieval for filler-gap assignment were associated with an enhanced negativity between 300 and 500 msec poststimulus over left anterior sites. This effect of left anterior negativity (LAN) was independent of and orthogonal to the grammaticality of the eliciting condition. We show how this interpretation coincides with recent studies that demonstrate a correlation between left anterior negativity, working memory capacity, and successful language processing.
Psychological correlates and psychiatric morbidity in patients with Dhat syndrome

Aim: The aim of this study was to examine psychological factors in the form of somatosensory amplification, alexithymia and hypochondriasis in patients with Dhat syndrome. Secondary aims of the study were: (1) To evaluate the influence of psychiatric comorbidity on the psychological correlates; (2) to compare the prevalence of psychological correlates in those with Dhat syndrome and in those with depression and somatoform disorders. Materials and Methods: A total of 106 subjects diagnosed with Dhat syndrome as per International Classification of Diseases-10 (ICD-10) criteria were assessed on Toronto Alexithymia Scale (TAS-20), Somatosensory Amplification Scale (SSAS) and Whitely Index (WI). Psychiatric comorbidity was diagnosed as per ICD-10. Data on 50 patients with depression and 119 patients with somatoform disorder was used for comparison. Results: The age at onset of Dhat syndrome was 22.54 (standard deviation [SD] - 7.5) years, and duration of illness was 5.04 (SD - 4.2) years. Depressive disorders were diagnosed in 13.2%, anxiety disorders in 15.1%, erectile dysfunction in 14.2% and premature ejaculation in 17% of cases. The mean SSAS total score was 23.12 (SD - 7.99), mean total TAS-20 score was 63.3 (SD - 13.3) and mean WI score was 8.23 (SD - 2.7). About two third of the patients had alexithymia (n = 67; 63.2%) and hypochondriasis (n = 69; 65.1%). Comparison of the psychological correlates between those with Dhat syndrome alone (n = 59) and those with comorbid psychiatric disorder (n = 47) revealed no significant differences. Patients with only Dhat syndrome had significantly higher scores for somatosensory amplification when compared with those with somatoform disorders, but no difference was seen between those with depression and Dhat syndrome alone. Compared to patients with Dhat syndrome alone, those with depression had higher prevalence of alexithymia and hypochondriasis. Conclusion: There are differences in the prevalence of somatosensory amplification, hypochondriasis and alexithymia between those with Dhat syndrome alone and those with depression and somatoform disorders.
Effective Equations for Sound and Void Wave Propagation in Bubbly Fluids

Effective equations that describe both sound wave and void wave propagation for bubbly flows at high Reynolds numbers are derived in this paper. First ideal bubble flows are considered, and a new method for solving Laplace's equation for the velocity potential is presented. This approach is based on a generalization of the method of images and also yields a precise definition of the ambient field experienced by a bubble. With the velocity potential known, the Lagrangian is then computed, and equations of motion for a finite number of bubbles using the Euler-Lagrange equations are derived. The continuum limit is then used to obtain our effective equations. Our expressions for the sound wave and void wave speeds agree well with previous investigations. The effects of gravity and viscosity on void waves are considered. Viscous effects are incorporated using a dissipation function. The steady rise speed and void wave speed for a column of rising bubbles are computed and found to agree well with experiments.
A new numerical technique for solving the local fractional diffusion equation: Two-dimensional extended differential transform approach

In this article, we first propose a new numerical technique based upon a certain twodimensional extended differential transform via local fractional derivatives and derive its associated basic theorems and properties. One example of testing the local fractional diffusion equation is then considered. The numerical result presented here illustrates the efficiency and accuracy of the proposed computational technique in order to solve the partial differential equations involving local fractional derivatives. © 2015 Elsevier Inc. All rights reserved.
Health related quality of life among the Thai people with unilateral lower limb amputation.

OBJECTIVE To study the health related quality of life (HRQOL) among Thai unilateral lower limb amputees and determine the factors associated with a good HRQOL. MATERIAL AND METHOD A postal survey with the WHOQOL-BREF-Thai questionnaire (26 items) to 1300 people with LLA who received a lower limb prostheses from Siriraj Hospital, Prapokklao Hospital, and Ratchaburi Hospital between 2001 and 2005 was conducted. Descriptive statistics were used to report the level of HRQOL. Chi-Square, independent Sample t-test and multivariate analysis by stepwise logistic regression were used to determine the factors associated with a good QOL. RESULTS Three hundred and nine questionnaires were completed from the 321 returned questionnaires (response rate 24.7%). Among these, 278 people were with unilateral LLA. They were 221 males and 57 females with mean age 46.9 +/- 13.9 years old. The number of people with LLA who had poor, fair and good QOL were 14 (5%), 241 (86.7%), and 23 (8.3%), respectively. Demographically, the people with LLA who had long duration of amputation (p = 0.001), higher education (p = 0.005), and had been employed after amputation (p < 0.001) had significantly better HRQOL. The amputees who had good wearing comfort (p = 0.04) after wearing the prostheses, had no phantom pain (p = 0.02), used no gait aids (p = 0.01), and had no body image anxiety (p = 0.01) had significantly better HRQOL. The factors associated with the good HRQOL were higher education (OR 3.2), having been employed after amputation (OR 2.1), and having good prosthetic wearing comfort (OR 1.3). CONCLUSION Thai people with unilateral LLA reported primarily fair HRQOL. Having higher education, having been employed after amputation, and having good prosthetic wearing comfort were associated with the good HRQL.
Defense Responses in Two Ecotypes of Lotus japonicus against Non-Pathogenic Pseudomonas syringae

Lotus japonicus is a model legume broadly used to study many important processes as nitrogen fixing nodule formation and adaptation to salt stress. However, no studies on the defense responses occurring in this species against invading microorganisms have been carried out at the present. Understanding how this model plant protects itself against pathogens will certainly help to develop more tolerant cultivars in economically important Lotus species as well as in other legumes. In order to uncover the most important defense mechanisms activated upon bacterial attack, we explored in this work the main responses occurring in the phenotypically contrasting ecotypes MG-20 and Gifu B-129 of L. japonicus after inoculation with Pseudomonas syringae DC3000 pv. tomato. Our analysis demonstrated that this bacterial strain is unable to cause disease in these accessions, even though the defense mechanisms triggered in these ecotypes might differ. Thus, disease tolerance in MG-20 was characterized by bacterial multiplication, chlorosis and desiccation at the infiltrated tissues. In turn, Gifu B-129 plants did not show any symptom at all and were completely successful in restricting bacterial growth. We performed a microarray based analysis of these responses and determined the regulation of several genes that could play important roles in plant defense. Interestingly, we were also able to identify a set of defense genes with a relative high expression in Gifu B-129 plants under non-stress conditions, what could explain its higher tolerance. The participation of these genes in plant defense is discussed. Our results position the L. japonicus-P. syringae interaction as a interesting model to study defense mechanisms in legume species.
A View on Imaging in Drug Research and Development for Respiratory Diseases

With the incidence of respiratory diseases increasing throughout the world, new therapies are needed. This review provides a short overview of different imaging techniques of interest for drug discovery and development within the pulmonary disease area. The focus is on studies performed in both animals and humans, which are of importance for understanding pathophysiological aspects and evaluating new drugs. Rather than emphasizing particular lung diseases, the noninvasive diagnosis and quantification of a number of characteristics related to several pathological conditions of the lung are addressed: inflammation, mucus secretion and clearance, emphysema, ventilation, perfusion, fibrosis, airway remodeling, and pulmonary arterial hypertension. Techniques are discussed based on their present use or potential future utilization in the context of drug studies.
How do Developers Test Android Applications?

Enabling fully automated testing of mobile applications has recently become an important topic of study for both researchers and practitioners. A plethora of tools and approaches have been proposed to aid mobile developers both by augmenting manual testing practices and by automating various parts of the testing process. However, current approaches for automated testing fall short in convincing developers about their benefits, leading to a majority of mobile testing being performed manually. With the goal of helping researchers and practitioners - who design approaches supporting mobile testing - to understand developer's needs, we analyzed survey responses from 102 open source contributors to Android projects about their practices when performing testing. The survey focused on questions regarding practices and preferences of developers/testers in-the-wild for (i) designing and generating test cases, (ii) automated testing practices, and (iii) perceptions of quality metrics such as code coverage for determining test quality. Analyzing the information gleaned from this survey, we compile a body of knowledge to help guide researchers and professionals toward tailoring new automated testing approaches to the need of a diverse set of open source developers.
Consequences of content diversity for online public spaces for local communities

While there is significant potential for social technologies to strengthen local communities, creating viable online spaces for them remains difficult. Maintaining a reliable content stream is challenging for local communities with their bounded emphases and limited population of potential contributors. Some systems focus on specific information types (e.g. restaurant, events). Others allow many different information types. This paper reports our findings about the consequences of content diversity from a study of neighborhood-oriented Facebook groups. The findings raise questions about the viability of designs for local online communities that focus narrowly on single topics, goals, and audiences.
ACCF/AHA/SCAI Practice Guideline 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: Executive Summary A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventi

ad hoc angioplasty, angioplasty, balloon angioplasty, clinical trial, coronary stenting, delayed angioplasty, meta-analysis, percutaneous transluminal coronary angioplasty, randomized controlled trial, percutaneous coronary intervention (PCI) and angina reduction, antiplatelet therapy, bare-metal stents (BMS), cardiac rehabilitation, chronic stable angina, complication, coronary bifurcation lesion, coronary calcified lesion, coronary chronic total occlusion, coronary ostial lesions, coronary stent (BMS and drug-eluting stents [DES]; and BMS versus diabetes, distal embolization, distal protection, elderly, ethics, late stent thrombosis, medical therapy, microembolization, mortality, multiple lesions, multivessel, myocardial infarction, non–ST-elevation myocardial infarction (NSTEMI), no-reflow, optical coherence tomography, proton pump inhibitor, return to work, same-day (SIHD), and pulmonary disease; COR, class recommendation; EF, ejection fraction; LAD, left anterior descending; LIMA, left internal mammary artery; LOE, level evidence; LV, left ventricular; N/A, applicable; PCI, percutaneous coronary intervention; SIHD, stable ischemic heart disease; STEMI, ST-elevation myocardial infarction; STS, Society of Thoracic Surgeons; SYNTAX, Synergy Percutaneous Coronary Intervention With Taxus and Cardiac Surgery; TIMI, Thrombolysis In Myocardial Infarction; angina/non–ST-elevation myocardial infarction; UPLM, and VT, This table represents all healthcare relationships of committee members with industry and other entities that were reported by authors, including those not deemed to be relevant to this document, at the time this document was under development. The table does not necessarily reflect relationships with industry at the time of publication. A person is deemed to have a significant interest in a business if the interest represents ownership of ≥ 5% of the voting stock or share of the business entity, or ownership of ≥ $10,000 of the fair market value of the business entity; or if funds received by the person from the business entity exceed 5% of the person’s gross income for the previous year. Relationships that exist with no financial benefit are also included for the purpose of transparency. Relationships in this table are modest unless otherwise noted. Please refer to http://www.cardiosource. org/Science-And-Quality/Practice-Guidelines-and-Quality-Standards/Relationships-With-Industry-Policy.aspx for definitions of disclosure categories or additional information about the ACCF/AHA Disclosure Policy for Writing Committees. significant
Randomized phase III trial of retinoic acid and arsenic trioxide versus retinoic acid and chemotherapy in patients with acute promyelocytic leukemia: health-related quality-of-life outcomes.

PURPOSE A randomized clinical trial compared efficacy and toxicity of standard all-trans-retinoic acid (ATRA) plus chemotherapy versus ATRA plus arsenic trioxide in patients with newly diagnosed, low- or intermediate-risk acute promyelocytic leukemia (APL). Here, we report health-related quality-of-life (HRQOL) results. PATIENTS AND METHODS HRQOL was a secondary end point of this trial. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 was used to assess HRQOL at end of induction and after consolidation therapy. All analyses were based on 156 patients who received at least one dose of treatment, with groups defined according to randomly assigned treatment. Primary analysis was performed, estimating mean HRQOL score over time and differences between treatment arms using a linear mixed model. RESULTS Overall, 162 patients age 18 to 70 years were enrolled. Of these, 150 and 142 patients were evaluable for HRQOL after induction therapy and third consolidation course, respectively. Overall compliance with HRQOL forms was 80.1%. The largest difference, favoring patients treated with ATRA plus arsenic trioxide, was found for fatigue severity (mean score difference, -9.3; 95% CI, -17.8 to -0.7; P = .034) at end of induction therapy. This difference was also clinically relevant. HRQOL differences between treatment arms at end of consolidation showed that for several scales, differences between treatment arms were marginal. CONCLUSION Overall, current HRQOL findings further support the use of ATRA plus arsenic trioxide as preferred first-line treatment in patients with low- or intermediate-risk APL.
Randomized CP tensor decomposition

The CANDECOMP/PARAFAC (CP) tensor decomposition is a popular dimensionality-reduction method for multiway data. Dimensionality reduction is often sought after since many high-dimensional tensors have low intrinsic rank relative to the dimension of the ambient measurement space. However, the emergence of ‘big data’ poses significant computational challenges for computing this fundamental tensor decomposition. By leveraging modern randomized algorithms, we demonstrate that coherent structures can be learned from a smaller representation of the tensor in a fraction of the time. Thus, this simple but powerful algorithm enables one to compute the approximate CP decomposition even for massive tensors. The approximation error can thereby be controlled via oversampling and the computation of power iterations. In addition to theoretical results, several empirical results demonstrate the performance of the proposed algorithm.
A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver disease and tumor burden. To minimize the impact to the patient while treating the tumor, techniques have been developed to target HCC. Anatomical targeting by surgical resection or locoregional therapies is generally reserved for patients with preserved liver function and minimal to moderate tumor burden. Patients with decompensated cirrhosis and small tumors are optimal candidates for liver transplantation, which offers the best chance of long-term survival. Yet, only 20%–30% of patients have disease amenable to anatomical targeting. For the majority of patients with advanced HCC, chemotherapy is used to target the tumor biology. Despite these treatment options, the five-year survival of patients in the United States with HCC is only 16%. In this review we provide a comprehensive overview of current approaches to target HCC. We also discuss emerging diagnostic and prognostic biomarkers, novel therapeutic targets identified by recent genomic profiling studies, and potential applications of immunotherapy in the treatment of HCC.
Total ozone time series analysis: a neural network model approach

This work is focused on the application of neu- ral network based models to the analysis of total ozone (TO) time series. Processes that affect total ozone are ex- tremely non linear, especially at the considered European mid-latitudes. Artificial neural networks (ANNs) are intrin- sically non-linear systems, hence they are expected to cope with TO series better than classical statistics do. Moreover, neural networks do not assume the stationarity of the data se- ries so they are also able to follow time-changing situations among the implicated variables. These two features turn NNs into a promising tool to catch the interactions between atmo- spheric variables, and therefore to extract as much informa- tion as possible from the available data in order to make, for example, time series reconstructions or future predictions. Models based on NNs have also proved to be very suitable for the treatment of missing values within the data series. In this paper we present several models based on neural net- works to fill the missing periods of data within a total ozone time series, and models able to reconstruct the data series. The results released by the ANNs have been compared with those obtained by using classical statistics methods, and bet- ter accuracy has been achieved with the non linear ANNs techniques. Different network structures and training strate- gies have been tested depending on the specific task to be accomplished.
Reported pain after day surgery: a critical literature review.

BACKGROUND Despite technological advancements in anaesthesia and analgesia, reported pain levels after day surgery remains high. Whilst it is unrealistic to expect no pain, the level that constitutes 'acceptable' pain remains unclear because of inconsistencies in reporting. These inconsistencies have resulted from different interpretations of what pain is and the use of different measurement tools. AIM The aim of this paper is to report a study investigating any disparity in reported levels of pain following day surgery, within different specialties and in relation to specific operative procedures. METHOD Nursing and health care papers published since 1983 were sought using the keywords: postoperative pain, postoperative complications, pain after day surgery, day surgery, ambulatory surgery, nursing, operation types, operative procedures, surgical procedures, descriptors of pain, pain intensity, verbal descriptor scale, numerical rating scale, visual analogue scale, validity, reliability, design, sample size, data collection methods and their various combinations. Databases searched were Medline, CINAHL, Nursing Collection, Embase, Healthstar, BMJ and several on-line Internet journals, specifically Ambulatory Surgery. The search was restricted to publications in the English language. Findings. Twenty-four papers were identified. Inconsistencies in the reported intensity of pain are highlighted, in relation to different operative procedures and specialties. Data in the papers are based on different descriptors, measurement tools and data collection methods. In many cases, sample size, and validity and reliability can also be questioned. CONCLUSIONS There is a disparity in reported levels of pain after day surgery. It is important that a unified day surgery pain measurement strategy is established, so that patients can be informed about the intensity of pain that they are likely to experience following specific procedures.