Miracle-dz/UniFAR-FTUs huggingface dataset:
A Unified Model for Word Sense Representation and Disambiguation

Most word representation methods assume that each word owns a single semantic vector. This is usually problematic because lexical ambiguity is ubiquitous, which is also the problem to be resolved by word sense disambiguation. In this paper, we present a unified model for joint word sense representation and disambiguation, which will assign distinct representations for each word sense. 1 The basic idea is that both word sense representation (WSR) and word sense disambiguation (WSD) will benefit from each other: (1) highquality WSR will capture rich information about words and senses, which should be helpful for WSD, and (2) high-quality WSD will provide reliable disambiguated corpora for learning better sense representations. Experimental results show that, our model improves the performance of contextual word similarity compared to existing WSR methods, outperforms stateof-the-art supervised methods on domainspecific WSD, and achieves competitive performance on coarse-grained all-words WSD.
Families’ and Nurses’ Responses to the “One Question Question”: Reflections for Clinical Practice, Education, and Research in Family Nursing

The “One Question Question,” first coined by Dr. Lorraine M. Wright in 1989, is an interventive question designed to elicit family members’ most pressing needs or concerns within the context of a therapeutic conversation. In this article, two clinical projects analyzed the responses to this unique interventive question. The first project analyzed the responses of 192 family members experiencing illness who were asked the question in the context of a therapeutic conversation; families focused on their need to deal with the impact of the illness on the family. The second project examined responses of 297 nurses who were asked the question prior to a 1-week Family Systems Nursing training program; nurses wanted to know how to deal with conflictual relationships between families and health care professionals and how to offer families time-efficient interventions. The responses from both groups, which were markedly different, triggered reflections about teaching, research, and practice in family nursing.
Detection of Pristine Gas Two Billion Years After the Big Bang

Two cosmic clouds have been observed with a composition close to that of the universe before the first stars were formed. In the current cosmological model, only the three lightest elements were created in the first few minutes after the Big Bang; all other elements were produced later in stars. To date, however, heavy elements have been observed in all astrophysical environments. We report the detection of two gas clouds with no discernible elements heavier than hydrogen. These systems exhibit the lowest heavy-element abundance in the early universe, and thus are potential fuel for the most metal-poor halo stars. The detection of deuterium in one system at the level predicted by primordial nucleosynthesis provides a direct confirmation of the standard cosmological model. The composition of these clouds further implies that the transport of heavy elements from galaxies to their surroundings is highly inhomogeneous.
Initial Salt Screening Procedures for Manufacturing Ibuprofen

The aim of this paper is to design initial salt screening procedures for manufacturing ibuprofen. Salt forms of a pharmaceutical acid racemic (R,S)-(±)-ibuprofen and their “developable” synthetic routes were ferreted out simultaneously through the screening of seven bases of sodium hydroxide, potassium hydroxide, l-arginine, l-histidine, l-lysine, diethanolamine, and tris(hydroxymethyl)aminomethane (THAM), and the match with the use of nine organic solvents of methanol, dimethyl sulfoxide, ethanol, N, N-dimethylformamide, acetonitrile, isopropyl alcohol, 1,4-dioxane, acetone, and tetrahydrofuran mainly in the presence of water in 20 mL scintillation vials. Racemic (R,S)-(±)-sodium ibuprofen dihydrate, a well-known ibuprofen salt and the newly discovered racemic (R,S)-(±)-THAM ibuprofen, appeared as white-squared powders with a molecular weight of 327.42 g/mol, a melting point of 160.17°C, and the apparent solubility product, K′sp, of 6.0 × 10−4 M2 at 25°C were successfully synthesized by the initial salt screening methods. The new amine salt of ibuprofen was monoclinic and had a space group of P21/c and lattice parameters of a = 17.578(8)°, b = 10.428(4)°, c = 9.991(4) Å, α = 90.00°, β = 97.17(1)°, γ = 90.00°, and V = 1,817.05(244) Å3. The aspect ratio of the amine salt crystals of ibuprofen of ≈ 1.0 implied that the crystals had a better flowability than the sodium salt counterparts. This amine salt of ibuprofen was more stable in moist or dried atmospheres and was more hydrophobic than the sodium salt of ibuprofen. Moreover, the slow dissolution of this amine salt of ibuprofen might have made it less bitter and more suitable as a sustained release drug than the sodium salt of ibuprofen. The future work is to search for the different polymorphs of this amine salt of ibuprofen and to extend the initial salt screening working logics to the formation of co-crystals.
Low latency DASH based streaming over LTE

Dynamic Adaptive Streaming over HTTP (DASH) is becoming the de facto technique for video delivery, especially for VoD services. Although 3GPP has specified carriage of DASH over eMBMS for Live Streaming, eMBMS is not available everywhere (operators are starting service rollout) and it is only worthwhile for reasonably large number of users due to the static SFN resource allocation for those services. Thus, Live Streaming using DASH over unicast connections is still necessary, which may suffer from playback interruptions when the throughput varies since the low end-to-end latency for live streaming requires small buffers. In order to cope with network throughput variations in mobile networks, we propose the usage of scalable video coding, combining it with parallel TCP connections and prioritizing the most important data of the scalable video. We show that using LTE non-GBR bearers for prioritization playback interruptions can be avoided.
Patient-to-patient transmission of hepatitis C virus during colonoscopy.

Invasive diagnostic or therapeutic procedures may be a route for the transmission of the hepatitis C virus (HCV). 1–5 In a study of patients in a gastrointestinal-disease unit, endoscopic biopsies were found to be an independent risk factor for HCV infection.6 We report the transmission of HCV during colonoscopy from a person known to have HCV infection to two other patients. The patient-to-patient transmission was ascertained by sequencing the nucleotides in the various HCV isolates. Case Report A 55-year-old man (Patient 1) and his 54-year-old wife (Patient 2) were referred in October 1995. In June 1995, both had had hepatitis-like .
Adaptive Base Station Cooperation for Physical Layer Security in Two-Cell Wireless Networks

We study physical layer security in two-cell wireless networks in which a base station (Alice) intends to send a confidential message to a legitimate user (Bob) with the help of a cooperative base station (Charlie), in the presence of an eavesdropper (Eve). Adaptive base station cooperation is explored to secure communication between Alice and Bob, and ensure the desired quality of service (QoS) at Charlie's user. In particular, we consider two different scenarios where the channel state information of Eve is perfectly and statistically known, respectively. In either scenario, we provide a cooperative transmission scheme for secrecy rate maximization, subject to both security and QoS constraints. Unlike the conventional cooperative security with a fixed transmission scheme, we propose a mechanism for transmit strategy adaptation with security protection. Specifically, the cooperative transmission is replaced by a cooperative jamming scheme if either security or QoS constraint is not satisfied. Our design enables adaptive secure transmission, and thus is flexible and environment-adaptive. Moreover, numerical results confirm that our scheme is efficient in power resource utilization.
Impact of Juvenile Idiopathic Arthritis Associated Uveitis in Early Adulthood

Background Typically juvenile idiopathic arthritis (JIA)-associated uveitis (further referred as ‘JIA-uveitis’) has its onset in childhood, but some patients suffer its, sometimes visual threatening, complications or ongoing disease activity in adulthood. The objective of this study was to analyze uveitis activity, complications and visual prognosis in adulthood. Methods In this multicenter study, 67 adult patients (129 affected eyes) with JIA-uveitis were retrospectively studied for best corrected visual acuity, visual fields, uveitis activity, topical/systemic treatments, ocular complications, and ocular surgeries during their 18th, 22nd and 30th year of life. Because treatment strategies changed after the year 1990, outcomes were stratified for onset of uveitis before and after 1990. Results Sixty-two of all 67 included patients (93%) had bilateral uveitis. During their 18th life year, 4/52 patients (8%) had complete remission, 28/52 (54%) had uveitis activity and 37/51 patients (73%) were on systemic immunomodulatory treatment. Bilateral visual impairment or legal blindness occurred in 2/51 patients (4%); unilateral visual impairment or legal blindness occurred in 17/51 patients (33%) aged 18 years. The visual prognosis appeared to be slightly better for patients with uveitis onset after the year 1990 (for uveitis onset before 1990 (n = 7) four patients (58%) and for uveitis onset after 1990 (n = 44) 13 patients (30%) were either visual impaired or blind). At least one ocular surgery was performed in 10/24 patients (42%) between their 18th and 22nd year of life. Conclusions Bilateral visual outcome in early adulthood in patients with JIA-uveitis appears to be fairly good, although one third of the patients developed one visually impaired or blind eye. However, a fair amount of the patients suffered from ongoing uveitis activity and needed ongoing treatment as well as surgical interventions. Awareness of these findings is important for ophthalmologists and rheumatologists treating patients with JIA-uveitis, as well as for the patients themselves.
Effects of thyroxine and donepezil on hippocampal acetylcholine content, acetylcholinesterase activity, synaptotagmin-1 and SNAP-25 expression in hypothyroid adult rats

A growing number of studies have revealed that neurocognitive impairment, induced by adult-onset hypothyroidism, may not be fully restored by traditional hormone substitution therapies, including thyroxine (T4). The present study has investigated the effect of T4 and donepezil (DON; an acetylcholinesterase (AChE) inhibitor) treatment on the hypothyroidism-induced alterations of acetylcholine (ACh) content and AChE activity. Furthermore, we examined synaptotagmin-1 (syt-1) and SNAP-25 expression in the hippocampus of adult rats. Adding 0.05% propylthiouracil to their drinking water for five weeks induced hypothyroidism in the rat models. From the fourth week, the rats were treated with T4, DON or a combination of both. Concentration of ACh and the activity of AChE was determined colorimetrically. The results demonstrated that hypothyroidism induced a significant decrease of Ach content and AChE activity (by 17 and 34%, respectively), which were restored to control values by T4 administration. DON treatment also restored Ach to the normal level. Protein levels of syt-1 and SNAP-25 were determined by immunohistochemistry. The results demonstrated that syt-1 was expressed at significantly lower levels in hypothyroid rats, while SNAP-25 levels were notably higher compared with the controls. Two-week treatment with T4 alone failed to normalize the expression levels of these two proteins, while co-administration of T4 and DON was able to induce this effect. These data suggested that the thyroid hormone, T4, may have a direct effect on the metabolism of hippocampal ACh in adult rats, and that the DON treatment may facilitate the recovery of synaptic protein impairments induced by hypothyroidism.
Quantitative and qualitative assessment of bone perfusion and arterial contributions in a patellar fracture model using gadolinium-enhanced magnetic resonance imaging: a cadaveric study.

BACKGROUND The purpose of the present study was to evaluate the anatomy and contribution of the patellar vascular supply and to quantify the effect of a transverse fracture on patellar perfusion. METHODS In twenty matched pairs of fresh-frozen cadaveric knees, the superficial femoral artery, anterior tibialis artery, and posterior tibialis artery were cannulated. One side of each matched pair was randomly selected to undergo one of two osteotomies: (1) midpatellar osteotomy or (2) distal-pole osteotomy. For volumetric analysis, comparisons were performed between contrast-enhanced magnetic resonance images and precontrast magnetic resonance images as well as between osteotomized patellar bone fragments and the corresponding intact areas on the control side. We then injected a urethane polymer compound and dissected all specimens to examine extraosseous vascularity. RESULTS Magnetic resonance imaging demonstrated that the largest arterial contribution to the patella entered at the inferior pole in 100% of the specimens; in 80% of these specimens, the artery entered inferomedially. It also revealed an overall decrease in contrast enhancement in both transverse osteotomy groups, with an average reduction in enhancement in the proximal fragment of 36%. CONCLUSIONS If possible, surgical interventions about the knee should be carefully planned to preserve the peripatellar ring (the source of the entire patellar blood supply), especially the inferior patellar network. Distal-pole patellectomy should be avoided to retain vascularized bone at the reduced fracture site.
Tracking from the Tropics Reveals Behaviour of Juvenile Songbirds on Their First Spring Migration

Juvenile songbirds on spring migration travel from tropical wintering sites to temperate breeding destinations thousands of kilometres away with no prior experience to guide them. We provide a first glimpse at the migration timing, routes, and stopover behaviour of juvenile wood thrushes (Hylocichla mustelina) on their inaugural spring migration by using miniaturized archival geolocators to track them from Central America to the U.S. and Canada. We found significant differences between the timing of juvenile migration and that of more experienced adults: juveniles not only departed later from tropical wintering sites relative to adults, they also became progressively later as they moved northward. The increasing delay was driven by more frequent short stops by juveniles along their migration route, particularly in the U.S. as they got closer to breeding sites. Surprisingly, juveniles were just as likely as adults to cross the Gulf of Mexico, an open-water crossing of 800–1000 km, and migration route at the Gulf was not significantly different for juveniles relative to adults. To determine if the later departure of juveniles was related to poor body condition in winter relative to adults, we examined percent lean body mass, fat scores, and pectoral muscle scores of juvenile versus adult birds at a wintering site in Belize. We found no age-related differences in body condition. Later migration timing of juveniles relative to adults could be an adaptive strategy (as opposed to condition-dependent) to avoid the high costs of fast migration and competition for breeding territories with experienced and larger adults. We did find significant differences in wing size between adults and juveniles, which could contribute to lower flight efficiency of juveniles and thus slower overall migration speed. We provide the first step toward understanding the “black box” of juvenile songbird migration by documenting their migration timing and en route performance.
Dimethyl (2Z)-2-[4-((1Z)-1-{2-[(2Z,5Z)-5-(2-methoxy-2-oxoethylidene)-4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene]hydrazin-1-ylidene}ethyl)anilino]but-2-enedioate

The molecule of the title compound, C26H24N4O7S, adopts a trans conformation about the central N—N bond, presumably to minimize steric between the substituents on these two atoms. An intramolecular N—H⋯O hydrogen bond occurs. The phenyl ring is disordered over two sets of sites, with an occupancy ratio of 0.624 (8):0.376 (8). The azolidine ring is essentially planar [maximum deviation = 0.008 (5) Å] and makes a dihedral angle of 4.3 (2)° with the benzene ring and dihedral angles of 74.1 (3) and 69.1 (5)°, respectively, with the mean planes of the major and minor components of the disordered phenyl ring. The packing in the crystal is aided by the formation of several weak C—H⋯O and C—H⋯N interactions.
Elephantiasis of non-filarial origin (podoconiosis) in the highlands of north–western Cameroon

Abstract Lymphoedema, a condition of localized fluid retention, results from a compromised lymphatic system. Although one common cause in the tropics is infection with filarial worms, non-filarial lymphoedema, also known as podoconiosis, has been reported among barefoot farmers in volcanic highland zones of Africa, Central and South America and north–western India. There are conflicting reports on the causes of lymphoedema in the highland regions of Cameroon, where the condition is of great public-health importance. To characterise the focus of lymphoedema in the highlands of the North West province of Cameroon and investigate its real causes, a cross-sectional study was carried out on the adults (aged ≥15 years) living in the communities that fall within the Ndop and Tubah health districts. The subjects, who had to have lived in the study area for at least 10 years, were interviewed, examined clinically, and, when possible, checked for microfilaraemia. The cases of lymphoedema confirmed by ultrasonography and a random sample of the other subjects were also tested for filarial antigenaemia. The interviews, which explored knowledge, attitudes and perceptions (KAP) relating to lymphoedema, revealed that the condition was well known, with each study community having a local name for it. Of the 834 individuals examined clinically, 66 (8.1%) had lymphoedema of the lower limb, with all the clinical stages of this condition represented. None of the 792 individuals examined parasitologically, however, had microfilariae of W. bancrofti (or any other filarial parasite) in their peripheral blood, and only one (0.25%) of the 399 individuals tested for the circulating antigens of W. bancrofti gave a positive result. In addition, none of the 504 mosquitoes caught landing on human bait in the study area and dissected was found to harbour any stage of W. bancrofti. These findings indicate that the elephantiasis seen in the North West province of Cameroon is of non-filarial origin.
Related donor hematopoietic stem cell transplantation for Fanconi anemia without radiation: A single center experience in Turkey

Abstract: Eight children with FA underwent allogeneic HSCT without using irradiation for the conditioning regimen. Patients received two different conditioning regimens: first two patients received BU 1.5 mg/kg/day for four days and CY 10 mg/kg/day for four days and the other regimen was: Flu 30 mg/m2/day for five days, CY 10 mg/kg/day for two days, and ATG‐Fresenius 9–10 mg/kg/day for four days. GVHD prophylaxis consisted of CsA + MTX for the first two patients and only CsA for the others. All patients received HLA‐identical stem cells from related donors. Primary engraftment was demonstrated in all patients. No patient developed acute GVHD and one patient had chronic GVHD. Only one patient who received BU based regimen died because of VOD. Overall, seven patients (87.5%) are alive with stable full donor chimerism at a median follow‐up time of 2.5 yr (range: 1.7–8.9 yr). None of the patients developed secondary malignancy. Based on our data, we conclude that Flu‐based, non‐irradiation conditioning regimen was safe with low organ toxicity and stable engraftment in FA patients undergoing HSCT from matched related donors.
An Additive Combinatorics Approach Relating Rank to Communication Complexity

For a {0, 1}-valued matrix M let CC(M) denote the deterministic communication complexity of the boolean function associated with M. It is well-known since the work of Mehlhorn and Schmidt [STOC 1982] that CC(M) is bounded from above by rank(M) and from below by log rank(M) where rank(M) denotes the rank of M over the field of real numbers. Determining where in this range lies the true worst-case value of CC(M) is a fundamental open problem in communication complexity. The state of the art is log1.631 rank(M) ≤ CC(M) ≤ 0.415 rank(M), the lower bound is by Kushilevitz [unpublished, 1995] and the upper bound is due to Kotlov [Journal of Graph Theory, 1996]. Lovasz and Saks [FOCS 1988] conjecture that CC(M) is closer to the lower bound, i.e., CC(M)≤ logcrank(M)) for some absolute constant c - this is the famous "log-rank conjecture'' - but so far there has been no evidence to support it, even giving a slightly non-trivial (o(rank(M))) upper bound on the communication complexity. Our main result is that, assuming the Polynomial Freiman-Ruzsa (PFR) conjecture in additive combinatorics, there exists a universal constant c such that CC(M) ≤ c ·rank(M)/log rank(M). Although our bound is stated using the rank of M over the reals, our proof goes by studying the problem over the finite field of size 2, and there we bring to bear a number of new tools from additive combinatorics which we hope will facilitate further progress on this perplexing question. In more detail, our proof is based on the study of the "approximate duality conjecture'' which was suggested by Ben-Sasson and Zewi [STOC 2011] and studied there in connection to the PFR conjecture. First we improve the bounds on approximate duality assuming the PFR conjecture. Then we use the approximate duality conjecture (with improved bounds) to get our upper bound on the communication complexity of low-rank martices.
On the bias of BFS (Breadth First Search)

Breadth First Search (BFS) and other graph traversal techniques are widely used for measuring large unknown graphs, such as online social networks. It has been empirically observed that incomplete BFS is biased toward high degree nodes. In contrast to more studied sampling techniques, such as random walks, the bias of BFS has not been characterized to date. In this paper, we quantify the degree bias of BFS sampling. In particular, we calculate the node degree distribution expected to be observed by BFS as a function of the fraction of covered nodes, in a random graph RG(pk) with a given (and arbitrary) degree distribution pk. Furthermore, we also show that, for RG(pk), all commonly used graph traversal techniques (BFS, DFS, Forest Fire, and Snowball Sampling) lead to the same bias, and we show how to correct for this bias. To give a broader perspective, we compare this class of exploration techniques to random walks that are well-studied and easier to analyze. Next, we study by simulation the effect of graph properties not captured directly by our model. We find that the bias gets amplified in graphs with strong positive assortativity. Finally, we demonstrate the above results by sampling the Facebook social network, and we provide some practical guidelines for graph sampling in practice.