Miracle-dz/UniFAR-FTUs huggingface dataset:
On the future of project management innovation: A call for discussion towards project management 2030

Rethinking Project Management (PM)∗ has been a recurring theme for some time [1]–[9]. In context of the current era of Digital Transformation, which is also referred to as the time of VUCA (Volatile, Uncertain, Complex and Ambiguous) it seems fair to assess if the current PM curricula match the needs of the market, both public and private. Professional bodies like IPMA† and PMI‡ similarly re-assess such which then leads to new editions of their standards to emerge. The current paper provides a short overview of the current developments of the profession. As well, it identifies related recent, current and ongoing research addressing similar questions regarding the success chances and rates of projects in light of the use and application of various PM methods. It aims to propose a new approach to learn using “Research through Project Management” (RtPM). Understanding the impact PM can have on the manner in which products, services, processes and systems are being developed, and the manner in which PM is performed. The authors propose the profession of PM will need to develop itself different from the way it has been conducted to-date and refer to it as “Towards Project Management 2030”, having the profession develop itself in a much more continuous manner. The paper ends with suggesting how to organize such ongoing research on, learning of and adoption by PM in practice embracing lifelong learning.
Effects of in ovo injection of different doses of coccidiosis vaccine and turn‐out times on broiler performance1,2,3

ABSTRACT Inovocox EM1 vaccine (EM1) is hatchery‐applied via in ovo injection for the control of coccidiosis in broiler chickens. Effects of 3 in ovo injection treatments (INT) and 2 turn‐out times (TOT) on the hatching chick quality variables and 35 d posthatch performance of Ross × Ross 708 broilers were investigated. In a single‐stage incubator, 1,440 hatching eggs were randomly distributed among 3 INT groups on each of 8 tray levels. At 19 d of incubation (doi), embryonated eggs were subjected to one of the following INT by in ovo injection: noninjected control; 1 × dose of EM1; 10 × dose of EM1. On 21 doi, hatchability of injected eggs (HI), hatching body weight (HBW), and hatching chick quality variables were determined. Additionally, for the grow‐out phase, birds belonging to each INT were randomly subjected to a 7 or 10 d TOT. Twenty chicks were initially placed in each of 48 floor pens (6 INT × TOT combination groups × 8 replications) for growth performance evaluation from 0 to 35 d posthatch. The main effect of INT on hatching chick quality variables, as well as the main and interactive effects of INT and TOT on various grow‐out performance variables were determined. Although there was no significant INT effect on HI or HBW, significant INT effects on chick total BW, yolk‐free BW, and yolk sac weight were observed. There were significant INT effects on BWG and FCR in the 21‐ to 28‐d posthatch interval, as well as on BWG and FCR in the 0‐ to 35‐d posthatch interval. There was no main effect of TOT or interactive effect of INT and TOT on BW and other performance variables from 0 to 35 d posthatch. There was a significant main effect of INT on relative intestine weight at 28 d posthatch. In conclusion, the injection of EM1 vaccine at a 10 × dose may affect hatching chick quality variables and growth performance up to 35 d posthatch.
A comparison of multiple imputation and fully augmented weighted estimators for Cox regression with missing covariates

Several approaches exist for handling missing covariates in the Cox proportional hazards model. The multiple imputation (MI) is relatively easy to implement with various software available and results in consistent estimates if the imputation model is correct. On the other hand, the fully augmented weighted estimators (FAWEs) recover a substantial proportion of the efficiency and have the doubly robust property. In this paper, we compare the FAWEs and the MI through a comprehensive simulation study. For the MI, we consider the multiple imputation by chained equation and focus on two imputation methods: Bayesian linear regression imputation and predictive mean matching. Simulation results show that the imputation methods can be rather sensitive to model misspecification and may have large bias when the censoring time depends on the missing covariates. In contrast, the FAWEs allow the censoring time to depend on the missing covariates and are remarkably robust as long as getting either the conditional expectations or the selection probability correct due to the doubly robust property. The comparison suggests that the FAWEs show the potential for being a competitive and attractive tool for tackling the analysis of survival data with missing covariates. Copyright © 2010 John Wiley & Sons, Ltd.
Erythrocyte oxidative stress is associated with cell deformability in patients with retinal vein occlusion

Essentials Retinal vein occlusion (RVO), characterized by blood hyperviscosity, has an unclear pathogenesis. We aimed to find out if hemorheological profile is altered by oxidative stress in RVO patients. Red blood cell (RBC) oxidative stress is associated to whole blood viscosity and RBC deformability. Reactive oxygen species alter RBC membrane rigidity, playing a key role in RVO pathogenesis.
Study of personality traits, individual coping resources, and their association in HIV-seropositive males

Background: HIV infection is an unfortunate consequence of a defined set of behaviors. Individuals with continued high-risk behavior either due to personality factors or due to maladaptive coping skills have higher viral loads and morbidity. Research has shown significant interactions between less effective coping styles and personality factors. Aim: This study aimed to evaluate personality traits, coping skills, and their association in male HIV-seropositive cases. Materials and Methods: This was a cross-sectional study, conducted on 86 patients. Informed consent and sociodemographic details, by a structured questionnaire, were obtained. Scales pertaining to personality factors and coping were applied. Statistical analysis was done by SPSS 16. Results: Neuroticism, extraversion, and conscientiousness traits were in the average range. Scores on openness and agreeableness were below average. The results pertaining to coping showed an overall mean score of 50.78, with the highest on physical domain and then on the philosophical domain, the lowest was in social domain. The research sample perceived their coping resources as average. Neuroticism was negatively related to all the coping styles. Extraversion showed relation with physical, emotional, social, and philosophical scales. Openness was related to philosophical and emotional scales. Agreeableness correlated with all domains of coping except the social. Conscientiousness correlated significantly with all the domains of coping. Conclusion: The various personality traits associated with male HIV-seropositive patients were identified and various coping resources used by these were also delineated. Further, the association among them was identified which can help in primary prevention and mental health professionals to have a targeted approach for counseling.
Highly Efficient Linear Regression Outsourcing to a Cloud

With cloud computing and mobile computing becoming more and more popular, there are a lot potential applications for computation outsourcing to the cloud. This paper investigates the linear regression outsourcing problem, which is a quite common engineering task and employed in various applications, as a case study to find out the possible problems that need to be solved. We propose two protocols which can enable secure and efficient outsourcing of linear regression problems to the cloud. The protocols can protect the client's data privacy well and at the same time have good efficiency. We show all subtleties and the techniques in designing such protocols. The main idea to protect the privacy is employing some transformations to the original linear regression problem to get a new problem which is sent to the cloud; and then transforming the answer returned back from the cloud to get the true solution to the original problem. Experimental results validate the practical usability of our protocols.
Home-based step training using videogame technology in people with Parkinson’s disease: a single-blinded randomised controlled trial

Objectives: To determine whether 12-week home-based exergame step training can improve stepping performance, gait and complementary physical and neuropsychological measures associated with falls in Parkinson’s disease. Design: A single-blinded randomised controlled trial. Setting: Community (experimental intervention), university laboratory (outcome measures). Subjects: Sixty community-dwelling people with Parkinson’s disease. Interventions: Home-based step training using videogame technology. Main measures: The primary outcomes were the choice stepping reaction time test and Functional Gait Assessment. Secondary outcomes included physical and neuropsychological measures associated with falls in Parkinson’s disease, number of falls over six months and self-reported mobility and balance. Results: Post intervention, there were no differences between the intervention (n = 28) and control (n = 25) groups in the primary or secondary outcomes except for the Timed Up and Go test, where there was a significant difference in favour of the control group (P = 0.02). Intervention participants reported mobility improvement, whereas control participants reported mobility deterioration—between-group difference on an 11-point scale = 0.9 (95% confidence interval: −1.8 to −0.1, P = 0.03). Interaction effects between intervention and disease severity on physical function measures were observed (P = 0.01 to P = 0.08) with seemingly positive effects for the low-severity group and potentially negative effects for the high-severity group. Conclusion: Overall, home-based exergame step training was not effective in improving the outcomes assessed. However, the improved physical function in the lower disease severity intervention participants as well as the self-reported improved mobility in the intervention group suggest home-based exergame step training may have benefits for some people with Parkinson’s disease.
Towards an Ontology of Goal-Oriented Requirements

Goal-Oriented Requirements Engineering (GORE) has grown into an important area of research in the past decades. Still, some of its corners remain dark, since diﬀerent GORE languages do not provide a well-founded conceptualization of the domain and are not consensual. This may lead to ambiguous or weak understanding of GORE concepts. In this paper, we introduce the Goal-Oriented Requirements Ontology (GORO), a domain ontology founded on the Uniﬁed Foundational Ontology (UFO) that intends to represent the nature and relations of concepts surrounding the GORE domain. We use GORO to explore and clarify the semantics used, sometimes implicitly, by well-known GORE languages.
On-Chip Ring Oscillator Based Scheme for TSV Delay Measurement

Due to the complexity of fabrication and bonding processes, TSVs are susceptible to delay defects and have become a serious concern in 3D ICs. To assure the quality and yield of 3D ICs, it is imperative to conduct effective delay testing for TSVs. In this paper, we present a novel on-chip ring oscillator based TSV delay measurement scheme for TSV delay defect detection. In the proposed scheme, three TSVs and the associated logic gates are implemented to construct a basic TSV propagation delay measurement unit. By configuring the control signals, three different oscillators can be created in the unit. By firstly measuring the oscillation periods of the three oscillators, the propagation delay of the target TSV can then be calculated with high resolution. Experimental results are presented to verify the effectiveness of the proposed scheme.
Dynamic QoS-Aware Resource Assignment in Cloud-Based Content-Delivery Networks

The problem of resource provisioning and content placement in cloud-based content delivery networks is studied, and a two-stage resource provisioning and cloud assignment is proposed based on dynamic large and small-scale fluctuations of user demand rates as well as considering a constrained minimum lease time for resources. In the first stage, we perform resource provisioning while costs of resources, quality of service (QoS) violation, and cloud-based root server redirection are included in the optimization, and constraints of QoS and limited resource of cloud sites are taken into account. In the second stage, cloud site assignment is conducted where for fixed allocated resources, QoS violation and cloud-based root server redirection costs are minimized or reduced using three different proposed schemes. We further show that reassignment of cloud sites during rising demand rates within a lease time period improves revenue, while reassignment is not very effective for falling demand rates.
Rabacfosadine for relapsed canine B‐cell lymphoma: Efficacy and adverse event profiles of 2 different doses

Rabacfosadine (RAB), a novel double prodrug of the acyclic nucleotide phosphonate PMEG, preferentially targets neoplastic lymphocytes with reduced off target toxicity. Historical studies have suggested that every 21-day dosing is effective with acceptable toxicity. The purpose of this study was to evaluate RAB's safety and efficacy at 2 different doses every 21 days in dogs with relapsed B-cell lymphoma. Dogs that had failed 1 doxorubicin-based chemotherapy protocol were eligible for inclusion in this prospective trial. Once enrolled, dogs were randomized to receive RAB at either 0.82 mg/kg or 1.0 mg/kg as a 30-minute IV infusion every 21 days for up to 5 treatments. Response assessment and adverse event (AE) evaluation were performed every 21 days via VCOG criteria. Fifty dogs were enrolled, with 16 treated at 0.82 mg/kg and 34 treated at 1.0 mg/kg. The overall response rate was 74%, with 45% of dogs experiencing a complete response (CR). The median progression free intervals (PFIs) were 108 days, 172 days and 203 days for all dogs, all responders, and all CRs, respectively. Response rates and PFIs were similar in both treatment groups. The incidence of AEs, dose delays, dose reductions and withdrawals were not statistically different between the 2 groups. The AEs observed were similar to those previously reported and included hematologic, gastrointestinal, dermatologic and pulmonary AEs. One dog had grade 5 pulmonary fibrosis; otherwise, AEs resolved with supportive treatment. Rabacfosadine is a generally well tolerated, effective chemotherapy option for dogs with relapsed B-cell lymphoma.
New construction of identity-based proxy re-encryption

A proxy re-encryption (PRE) scheme involves three parties: Alice, Bob, and a proxy. PRE allows the proxy to translate a ciphertext encrypted under Alice's public key into one that can be decrypted by Bob's secret key. We present a general method to construct an identity-based proxy re-encryption scheme from an existing identity-based encryption scheme. The transformed scheme satisfies the properties of PRE, such as unidirectionality, non-interactivity and multi-use. Moreover, the proposed scheme has master key security, allows the encryptor to decide whether the ciphertext can be re-encrypted.
Sociodemographic, psychiatric and somatic risk factors for suicide: a Swedish national cohort study

Background More effective prevention of suicide requires a comprehensive understanding of sociodemographic, psychiatric and somatic risk factors. Previous studies have been limited by incomplete ascertainment of these factors. We conducted the first study of this issue using sociodemographic and out-patient and in-patient health data for a national population. Method We used data from a national cohort study of 7140589 Swedish adults followed for 8 years for suicide mortality (2001–2008). Sociodemographic factors were identified from national census data, and psychiatric and somatic disorders were identified from all out-patient and in-patient diagnoses nationwide. Results There were 8721 (0.12%) deaths from suicide during 2001–2008. All psychiatric disorders were strong risk factors for suicide among both women and men. Depression was the strongest risk factor, with a greater than 15-fold risk among women or men and even higher risks (up to 32-fold) within the first 3 months of diagnosis. Chronic obstructive pulmonary disease (COPD), cancer, spine disorders, asthma and stroke were significant risk factors among both women and men (1.4–2.1-fold risks) whereas diabetes and ischemic heart disease were modest risk factors only among men (1.2–1.4-fold risks). Sociodemographic risk factors included male sex, unmarried status or non-employment; and low education or income among men. Conclusions All psychiatric disorders, COPD, cancer, spine disorders, asthma, stroke, diabetes, ischemic heart disease and specific sociodemographic factors were independent risk factors for suicide during 8 years of follow-up. Effective prevention of suicide requires a multifaceted approach in both psychiatric and primary care settings, targeting mental disorders (especially depression), specific somatic disorders and indicators of social support.
Time Spent on Social Network Sites and Psychological Well-Being: A Meta-Analysis

This meta-analysis examines the relationship between time spent on social networking sites and psychological well-being factors, namely self-esteem, life satisfaction, loneliness, and depression. Sixty-one studies consisting of 67 independent samples involving 19,652 participants were identified. The mean correlation between time spent on social networking sites and psychological well-being was low at r = -0.07. The correlations between time spent on social networking sites and positive indicators (self-esteem and life satisfaction) were close to 0, whereas those between time spent on social networking sites and negative indicators (depression and loneliness) were weak. The effects of publication outlet, site on which users spent time, scale of time spent, and participant age and gender were not significant. As most included studies used student samples, future research should be conducted to examine this relationship for adults.
How Emerging Organizations Take Form: The Role of Imprinting and Values in Organizational Bricolage

We examine how emerging organizations acquire shape by drawing on multiple organizational forms, a process we call organizational bricolage. Studying Indymedia London, a grassroots media collective, we propose a grounded theory of organizational bricolage that identifies how various types of organizational forms are selected and how they are instantiated into the organization. Whereas extant research has emphasized imprinting as a primary mechanism shaping newly founded organizations, we point to the additional role of organizational values. Emerging organizations augment their imprinted forms by using ancillary forms aligned with their organizational values and reinforce their core features by differentiating themselves from antagonistic forms that conflict with their values. We contribute to the literature on organizational formation by developing a process model that details how imprinted forms are subsequently modified. Moreover, we extend theories of bricolage by specifying the limits to the relative arbitrariness of bricolage as an activity, and we contribute to the study of organizational values by suggesting that they act as a focusing device shaping organizational structure.
The Long-Term Course of Outcomes for Lumbar Intervertebral Disc Herniation following Integrated Complementary and Alternative Medicine Inpatient Treatment: A Prospective Observational Study

A prospective observational study was conducted in 524 lumbar intervertebral disc herniation (LDH) inpatients to report the long-term effects of complementary and alternative medicine (CAM) treatment. Participants received integrative CAM treatment during hospitalization, from June 2012 to May 2013, and long-term outcomes were assessed from July to August 2016. Numerical rating scales (NRSs) of back and leg pain, the Oswestry disability index (ODI), satisfaction, surgery, recurrence, and current care status were investigated. Baseline characteristics were analyzed to determine factors that predicted long-term satisfaction. A total of 367 patients were available for follow-up. The long-term change in NRS of back and leg pain and ODI was 3.53 (95% CI, 3.22, 3.83), 2.72 (2.34, 3.11), and 32.89 (30.21, 35.57), respectively, showing that improvements were well sustained. Regarding satisfaction, 86.11% responded that they were “slightly improved” or better. Range of lumbar flexion ≤ 60° and both legs' pain at admission were significant predictors of “much improved” or better satisfaction in the long term. Overall, LDH patients who received CAM treatment maintained favorable states in the long term. However, as an uncontrolled observational study, further studies with placebo and/or active controls are warranted. Trial Registration. This trial is registered with ClinicalTrials.gov NCT02257723 (date of registration: October 2, 2014).
Keep on Track: A Volunteer‐Run Community‐Based Intervention to Lower Blood Pressure in Older Adults

Uncontrolled hypertension in older adults is a common yet preventable threat to healthy aging. Improvements in blood pressure (BP) control and related health outcomes require innovative approaches that reach beyond the clinical environment. Keep on Track (KOT), a volunteer‐run, community‐based BP‐monitoring program that aims to lower BP of community‐dwelling older adults through senior center programming, is described and evaluated. KOT is based on a New York City (NYC) Department for the Aging program that has been in existence for more than 20 years and is evaluated in six senior centers in low‐ to middle‐income neighborhoods in NYC. Program design includes monitoring sessions every other week to measure and record participant BP. BP education is provided using low‐literacy materials, and medication adherence is encouraged. Over 6 months of observation, 244 participants enrolled (mean age 73). Of the 181 (74%) with hypertension at baseline, 92% were previously aware of their condition, 78% were treated, and 31% were controlled. BP control among the treated was 42%. Forty‐three percent of enrollees (n=105) were multiple‐visit participants who experienced on average a 3.9‐mmHg reduction in systolic BP (SBP) between the first and last program visit (95% confidence interval (CI)=−7.6 to −0.1, P=. 04). Participants with an initial SBP greater than 160 mmHg (n=20) experienced on average a 20.9‐mmHg reduction in SBP (95% CI=−32.4 to −9.4, P<.001). Areas for program improvement include greater attention to peer counseling and timely communication with participants' healthcare providers. Volunteer‐run, community‐based BP monitoring in senior centers may provide an effective, replicable model for reducing BP in older adults.