Miracle-dz/UniFAR-FTUs huggingface dataset:
Strategic human resource management practices : mediator of total quality management and competitiveness ( a study on small and medium enterprises in kendari southeast sulawesi )

The purpose of this study is to explore and test the influence of implementation of Total Quality Management (TQM) and Strategic Human Resource Management (SHRM) towards competitiveness. More specific purpose is to test the role of SHRM practices as a mediator of relationship between TQM practices and competitiveness. The design of this study used the survey method with data collection through questionnaire. Method of data analysis applied structural equation modeling. The results showed that TQM practices has significant influence toward SHRM practices and competitiveness. Furthermore, SHRM has positive and significant influence toward competitiveness. SHRM practices eventually proved to be a partial mediation link between the implementation of TQM practices and competitiveness. The practical implications of these studies provide knowledge and information for SMEs in an attempt to improve competitiveness through the application of the concept of TQM and SHRM. In addition it is expected to provide an understanding of new thinking in the effort to streamline the program empowerment of SME particularly in the furniture industry and other SMEs in Kendari Southeast Sulawesi Province. Originality of research can prove the test configuration model of integrated relationship between the implementation of TQM and SHRM practices to increased competitiveness. The role of mediation of SHRM practices proved significant influence on increasing competitiveness. Keywords––Competitiveness, SHRM, Total Quality Management.
On the Temporary Couples in the Flowing China

In 2013,Liu Li,the NPC representative,mentioned the problem of temporary couples under migrant tide.Subsequently,media began to pay close attention to it and did some reports and investigations,which reflects the living dilemma of migrant workers in contemporary China.Based on this phenomenon,this paper employs theoretical perspective of sociology to analyze temporary couples:first,this paper explores the definition and the legalization of expression on the phenomenon;second,this paper reviews it from a historical dimension and overseas comparative perspective;finally,this paper interprets the reasons for it appearance from a macro perspective of changes in social structure and primary living area.
Primary Hyperparathyroidism in an Adolescent Girl

he aim of this paper is to present the case of a 15.5 year old girl with primary hyperparathyroidism (PHPT) with symptoms of bone pain that appeard 23 years prior to admission; she had suffered bone fracture six months earlier and had high serum calcium, very high serum PTH and low serum phosphorous levels, all results being in agreement with PHPT. The diagnosis was confirmed by imaging studies with 99m TC-Sestamibi scan, showing an adenoma in parathyroid tissue. The adenoma was removed by surgical operation. After surgery the patient was treated by high doses of calcium and vitamin D to avoid postoperative hypocalcemia.
Subaru Deep Survey. III. Evolution of Rest-Frame Luminosity Functions Based on the Photometric Redshifts for a K′-Band-Selected Galaxy Sample

We have constructed a very deep K′-selected multicolor BVRIz′JK′ sample of 439 field galaxies. Based on this multicolor data, a photometric redshift for each sample galaxy was estimated. The overall redshift distribution N(z) for the K′ ≤ 21.0 sample is consistent with previous observations, and for the first time we derive N(z) down to K′ = 24.0. After taking account of the dust extinction and selection effects of the sample, the observed N(z) distribution is well described with the pure luminosity evolution (PLE) model, while the hierarchical galaxy formation model shows an apparent deficiency of galaxies especially at z ≳ 2. The photometric redshift and the best-fit spectral energy distribution model evaluations allow the derivation of the rest-frame K′, B, and UV (2000 Å) band luminosity functions and their evolutions. The rest K′-band luminosity function shows almost no evolution up to z = 3, while the rest B luminosity function shows mild luminosity evolution, and the rest UV luminosity function shows strong luminosity evolution. These findings seem to be qualitatively in favor of the PLE model. No evolution in the rest K′-band luminosity function can also be consistent with the hierarchical galaxy formation model if M/LK decreases with redshift, that is, if the number density of K′-band luminosity-selected galaxies does not significantly change with redshift while the number density of stellar mass–selected galaxies decreases with look-back time. This trend corresponds to the evolution of the rest UV (2000 Å)-K′ color, which gets bluer with increasing redshift. We also found that more massive galaxies are redder in this rest-frame color in every epoch. The rest UV luminosity function of our K′-selected galaxies shows a much shallower faint-end slope at z = 3 than that of previous estimations for rest UV–selected Lyman break galaxies. As a consequence, the contribution to the global star formation rate of our K′-selected galaxies is about 42% of that derived from the integration of the luminosity function of Lyman break galaxies at z = 3. This result suggests that a large fraction of the star formation rate density at z > 1.5 comes from the contribution from a faint (M2000 > -20) blue galaxy population at high redshift that has not yet obviously been identified.
A reference genome of the Chinese hamster based on a hybrid assembly strategy

Accurate and complete genome sequences are essential in biotechnology to facilitate genome‐based cell engineering efforts. The current genome assemblies for Cricetulus griseus, the Chinese hamster, are fragmented and replete with gap sequences and misassemblies, consistent with most short‐read‐based assemblies. Here, we completely resequenced C. griseus using single molecule real time sequencing and merged this with Illumina‐based assemblies. This generated a more contiguous and complete genome assembly than either technology alone, reducing the number of scaffolds by >28‐fold, with 90% of the sequence in the 122 longest scaffolds. Most genes are now found in single scaffolds, including up‐ and downstream regulatory elements, enabling improved study of noncoding regions. With >95% of the gap sequence filled, important Chinese hamster ovary cell mutations have been detected in draft assembly gaps. This new assembly will be an invaluable resource for continued basic and pharmaceutical research.
Children's attitudes and behavioral intentions toward a peer presented as obese: does a medical explanation for the obesity make a difference?

OBJECTIVE To examine the effect of information on children's attitudes and behavioral intentions toward a peer presented as obese. METHODS Children (N = 184) were randomly assigned to observe a video of a boy or girl in one of three conditions: average-weight, obese, obese with medical information explaining the obesity. They rated stereotypical attitudes on the Adjective Checklist and behavioral intentions on the Shared Activities Questionnaire (SAQ-B). RESULTS Ratings were generally more favorable for the average-weight than for the obese condition. However, provision of medical information had a positive effect on attitudes toward the obese peer only for younger children and a negative effect on willingness of older children to share academic activities with the peer. Boys and girls showed more positive behavioral intentions toward the same-sex target child regardless of obesity condition. CONCLUSIONS Information explaining obesity has a minimal positive effect on children's attitudes and behavioral intentions toward a peer presented as obese.
Calculation of Motor Capacitances for Prediction of the Voltage Across the Bearings in Machines of Inverter-Based Drive Systems

The occurrence of high-frequency discharge bearing currents (also called "electric discharge machining (EDM) currents") that can occur in machines of inverter-based drive systems depends strongly on the value of the capacitive voltage divider "bearing voltage ratio" (BVR) of the machine. This paper presents a straightforward approach to calculate the involved motor capacitances in order to predict the voltage across the bearing and, thereby, the likeliness of such EDM currents that are caused by this voltage to occur. The approach is based on the design parameters of the machine and does not involve additional measurements. It combines ease of application and satisfying accurateness, and allows prediction of the risk of endangerment of an inverter-based drive system due to discharge bearing currents
High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain

Significance Clinical studies have demonstrated that resting-state functional connectivity (RSFC) is altered in many brain disorders. However, current RSFC imaging techniques cannot be easily applied to mice, the most widely used model species for human brain disease studies. Utilizing optical excitation and acoustic detection, we have developed a functional connectivity photoacoustic tomography (fcPAT) system, which allows noninvasive imaging of RSFC in the mouse brain, with a large field of view and high spatial resolution. In this article, we describe the unique strengths of fcPAT, as demonstrated by our experimental results. Considering the tremendous amount of brain research in mouse models, this work will elicit broad interest in many related fields. The increasing use of mouse models for human brain disease studies presents an emerging need for a new functional imaging modality. Using optical excitation and acoustic detection, we developed a functional connectivity photoacoustic tomography system, which allows noninvasive imaging of resting-state functional connectivity in the mouse brain, with a large field of view and a high spatial resolution. Bilateral correlations were observed in eight functional regions, including the olfactory bulb, limbic, parietal, somatosensory, retrosplenial, visual, motor, and temporal regions, as well as in several subregions. The borders and locations of these regions agreed well with the Paxinos mouse brain atlas. By subjecting the mouse to alternating hyperoxic and hypoxic conditions, strong and weak functional connectivities were observed, respectively. In addition to connectivity images, vascular images were simultaneously acquired. These studies show that functional connectivity photoacoustic tomography is a promising, noninvasive technique for functional imaging of the mouse brain.
Cluster-like Headache Secondary to Cerebral Venous Thrombosis

Cluster headache (CH) is considered a primary headache syndrome. However, symptomatic cases that resemble CH have also been reported. A patient with cerebral venous thrombosis presented with ipsilateral frontal pain accompanied by ophthalmoparesis, nasal congestion, and lacrimation. The patient's headache showed a dramatic response to oxygen. He experienced no further cluster-like headaches after treatment with an anticoagulant. This case suggests the possible role of venous stasis of the cavernous sinus in cluster-like headache.
Demographics and Personality Factors of Participants in the MSF 100 Motorcyclist Naturalistic Study

This paper describes a 100-rider naturalistic motorcycle study in terms of participant demographics, riding preferences, and behaviors collected through five questionnaires (NEO-FFI-3, Dula Dangerous Driving Index, Frequency of Risky Behavior, Barkley Adult ADHD Rating Scale–IV, and the Motorcycle Safety Foundation Rider Survey). The analysis of the questionnaire data is divided into three bike Types (Touring, Cruiser, Sport). The results indicate that self-reported mileage traveled was highest among Touring bike riders, followed by Sport riders, then Cruiser riders. Differences in Personality factors between Motorcycle Types was generally not found, with the exception of lower levels of Neuroticism in riders of the Touring bikes compared to riders of Cruisers and Sport. The survey based measures indicate that the participant sample does include some measurable heterogeneity in neuroticism scores purely based on questionnaires.
A Population Pharmacokinetic Model for a Solid Oral Tablet Formulation of Posaconazole

ABSTRACT A delayed-release solid tablet formulation that releases posaconazole in the small intestine was developed to maximize systemic absorption. This study aimed to characterize the pharmacokinetics of the posaconazole solid tablet formulation in adult subjects and to investigate the potential impact of demographic and clinical factors on posaconazole exposure through a population pharmacokinetic approach. Nonlinear mixed-effects modeling was performed using data from several studies conducted in healthy volunteers and patients. The influence of demographic and clinical factors on pharmacokinetic parameters was evaluated using a stepwise forward inclusion/backward exclusion procedure. The final pharmacokinetic model was used to simulate posaconazole exposure in patients at high risk for invasive fungal diseases treated with the proposed posaconazole dose of 300 mg twice daily on day 1, followed by 300 mg daily for 27 days. A one-compartment pharmacokinetic model with sequential zero-order and first-order absorption and a first-order disposition from the central compartment adequately described the pharmacokinetic profile of the posaconazole solid tablet formulation. Significant covariates included disease state (acute myeloid leukemia/myelodysplasia versus allogeneic hematopoietic stem cell transplantation), body weight, and formulation on bioavailability; food status on first-order absorption rate; and dosing regimen (a single dose versus multiple doses) on clearance. Except for body weight, the impact of these covariates on posaconazole exposure was considered clinically irrelevant. This population pharmacokinetic analysis confirmed that the proposed dose of the posaconazole solid tablet formulation provides adequate target therapeutic exposure (>0.5 mg/liter) to a broad range of patients at high risk for invasive fungal disease.
Ectopic trkA expression mediates a NGF survival response in NGF- independent sensory neurons but not in parasympathetic neurons

We have investigated the role of trkA, the tyrosine kinase NGF receptor, in mediating the survival response of embryonic neurons to NGF. Embryonic trigeminal mesencephalic (TMN) neurons, which normally survive in the presence of brain-derived neurotrophic factor (BDNF) but not NGF, become NGF-responsive when microinjected with an expression vector containing trkA cDNA. In contrast, microinjection of ciliary neurotrophic factor (CNTF)-dependent embryonic ciliary neurons with the same construct does not result in the acquisition of NGF responsiveness by these neurons despite de novo expression of trkA mRNA and protein. The failure of trkA to result in an NGF-promoted survival response in ciliary neurons is not due to absence of the low-affinity NGF receptor, p75, in these neurons. Quantitative RT/PCR and immunocytochemistry showed that TMN and ciliary neurons both express p75 mRNA and protein. These findings not only provide the first direct experimental demonstration of trkA mediating a physiological response in an appropriate cell type, namely NGF-promoted survival of embryonic neurons, but indicate that not all neurons are able to respond to a trkA-mediated signal transduction event.
Career satisfaction for managerial and technical anchored IS personnel in later career stages

Information system (IS) personnel have exhibit high incidence of technical and managerial anchors. It has been proposed that IS personnel with technical anchors have difficultly moving into a more advanced career stage that requires a greater emphasis on managerial skills (e.g., leadership) and activities. Using the data from a survey of IS professionals, we find that career satisfaction is positively and significantly correlated with career stage. Moreover, managerially anchored IS professionals are found to be more satisfied in the mentor stage than those who are technically anchored. However, no clear relationship between career anchors and career satisfaction was found in the sponsor stage. It appears that the combined effects of career anchor and stage is a more complex relation than previously thought in the literature. The results indicate that career programs discussed in the literature may need to be adjusted to accommodate advancement for those with a technical career anchor.
Food Price Bubbles and Government Intervention: Is China Different?

The last decade has witnessed different price trajectories in the international and Chinese agricultural commodity markets. This paper compares and contrasts these dynamic patterns between markets from the perspective of price bubbles. A newly developed right-tailed unit root testing procedure is applied to detect price bubbles in the Chicago Board of Trade (CBOT) and Chinese agricultural futures market during the period 2005–14. Results show that Chinese markets experienced less prominent speculative bubbles than the international markets for its high self-sufficiency commodities (wheat and corn), but not for low self-sufficiency commodities (soybean). The difference in price behavior is attributed to differences in market intelligence, and to Chinese agricultural policies related to trade as well as domestic government policies. Besides, it discusses challenges to the sustainability of the stable price trajectory in Chinese markets. Au cours de la derniere decennie, les prix des produits agricoles sur les marches chinois et international ont suivi des trajectoires variees. Dans le present article, nous comparons les divers marches sur le plan des bulles de prix des produits agricoles. Nous avons utilise un nouveau test de racine unitaire qui exploite la queue de droite de la distribution de la statistique pour deceler les bulles de prix des produits agricoles sur le Chicago Board of Trade (CBOT) et sur les marches a terme chinois au cours de la periode 2005–14. Les resultats de notre etude montrent que les marches chinois ont connu des bulles speculatives moins prononcees que les marches internationaux dans le cas des produits agricoles pour lesquels l'autosuffisance de la Chine est tres elevee (le ble et le mais), par rapport aux produits pour lesquels l'autosuffisance est faible (le soja). La difference sur le plan du comportement des prix est attribuable aux differences sur le plan de l'information commerciale ainsi qu'aux politiques agricoles chinoises en matiere de commerce et a la politique interieure du pays. Nous avons egalement examine les defis par rapport a la durabilite d'une trajectoire de prix stables sur les marches chinois.
Sparse Linear Dynamical System with Its Application in Multivariate Clinical Time Series

Linear Dynamical System (LDS) is an elegant mathematical framework for modeling and learning multivariate time series. However, in general, it is difficult to set the dimension of its hidden state space. A small number of hidden states may not be able to model the complexities of a time series, while a large number of hidden states can lead to overfitting. In this paper, we study methods that impose an $\ell_1$ regularization on the transition matrix of an LDS model to alleviate the problem of choosing the optimal number of hidden states. We incorporate a generalized gradient descent method into the Maximum a Posteriori (MAP) framework and use Expectation Maximization (EM) to iteratively achieve sparsity on the transition matrix of an LDS model. We show that our Sparse Linear Dynamical System (SLDS) improves the predictive performance when compared to ordinary LDS on a multivariate clinical time series dataset.
The ACS Survey of Galactic Globular Clusters. I. Overview and Clusters without Previous Hubble Space Telescope Photometry

We present the first results of a large Advanced Camera for Surveys (ACS) survey of Galactic globular clusters. This Hubble Space Telescope (HST) Treasury project is designed to obtain photometry with S/N (signal-to-noise ratio) ≳10 for main-sequence stars with masses ≳0.2 M⊙ in a sample of globulars using the ACS Wide Field Channel. Here we focus on clusters without previous HST imaging data. These include NGC 5466, NGC 6779, NGC 5053, NGC 6144, Palomar 2, E3, Lyngå 7, Palomar 1, and NGC 6366. Our color-magnitude diagrams (CMDs) extend reliably from the horizontal branch to as much as 7 mag fainter than the main-sequence turnoff and represent the deepest CMDs published to date for these clusters. Using fiducial sequences for three standard clusters (M92, NGC 6752, and 47 Tuc) with well-known metallicities and distances, we perform main-sequence fitting on the target clusters in order to obtain estimates of their distances and reddenings. These comparisons, along with fitting the cluster main sequences to theoretical isochrones, yield ages for the target clusters. We find that the majority of the clusters have ages that are consistent with the standard clusters at their metallicities. The exceptions are E3, which appears ∼2 Gyr younger than 47 Tuc, and Pal 1, which could be as much as 8 Gyr younger than 47 Tuc.
Eccentricity Evolution in Simulated Galaxy Clusters

Strong cluster eccentricity evolution for z ≤ 0.13 has appeared in a variety of observational data sets. We examine the evolution of eccentricity in simulated galaxy clusters using a variety of simulation methodologies, amplitude normalizations, and background cosmologies. We do not find such evolution for z < 0.1 in any of our simulation ensembles. We suggest a systematic error in the form of a redshift-dependent selection effect in cluster catalogs or missing physics in cluster simulations important enough to modify the cluster morphology.
Attenuation of Vascular Smooth Muscle Cell Proliferation by 1-Cyclohexyl-3-dodecyl Urea Is Independent of Soluble Epoxide Hydrolase Inhibition

Epoxyeicosatrienoic acid(s) (EET) have variable hemodynamic, anti-inflammatory, and growth regulatory effects, and inhibitors of their regulatory enzyme, soluble epoxide hydrolase (sEH), can mimic these effects. For this reason, sEH inhibitors are being studied as potential pharmaceuticals for the treatment of hypertension, atherosclerosis, and inflammatory diseases. We now show that a highly selective urea-based sEH inhibitor 1-cyclohexyl-3-dodecyl urea (CDU) attenuates human aortic vascular smooth muscle (HVSM) cell proliferation independently of any effect on sEH. CDU also inhibits endothelial cells when stimulated with basic fibroblast growth factor or serum. In addition, we demonstrate that EET, as well as several newer generation sEH inhibitors and a urea-based weak sEH inhibitor, do not affect proliferation in HVSM cells. Structure-activity relationships demonstrate that the addition of an acid group to the dodecyl carbon chain, changing the cyclohexyl group to an adamantyl group, and shortening the carbon chain to two carbons all abolish the antiproliferative effect. Our finding that a highly selective urea-based inhibitor of sEH can alter biology independently of its putative target enzyme suggests that there may be other useful properties of this class of compounds unrelated to their influence on epoxyeicosanoids. In addition, our results show that caution should be used when attempting to infer conclusions of EET biology based solely on the effects these inhibitors in tissue culture models, especially when used at micromolar concentrations.