Miracle-dz/UniFAR-FTUs huggingface dataset:
Residence time, native range size, and genome size predict naturalization among angiosperms introduced to Australia

Abstract Although critical to progress in understanding (i) if, and (ii) at what rate, introduced plants will naturalize and potentially become invasive, establishing causal links between traits and invasion success is complicated by data gaps, phylogenetic nonindependence of species, the inability to control for differences between species in residence time and propagule pressure, and covariance among traits. Here, we focus on statistical relationships between genomic factors, life history traits, native range size, and naturalization status of angiosperms introduced to Australia. In a series of analyses, we alternately investigate the role of phylogeny, incorporate introduction history, and use graphical models to explore the network of conditional probabilities linking traits and introduction history to naturalization status. Applying this ensemble of methods to the largest publicly available data set on plant introductions and their fates, we found that, overall, residence time and native range size best predicted probability of naturalization. Yet, importantly, probability of naturalization consistently increased as genome size decreased, even when the effects of shared ancestry and residence time in Australia were accounted for, and that this pattern was stronger in species without a history of cultivation, but present across annual–biennials, and herbaceous and woody perennials. Thus, despite introduction biases and indirect effects of traits via introduction history, across analyses, reduced genome size was nevertheless consistently associated with a tendency to naturalize.
Electrophysiological Characteristics of Globus Pallidus Neurons

Extracellular recordings in primates have identified two types of neurons in the external segment of the globus pallidus (GPe): high frequency pausers (HFP) and low frequency bursters (LFB). The aim of the current study was to test whether the properties of HFP and LFB neurons recorded extracellularly in the primate GPe are linked to cellular mechanisms underlying the generation of action potential (AP) firing. Thus, we recorded from primate and rat globus pallidus neurons. Extracellular recordings in primates revealed that in addition to differences in firing patterns the APs of neurons in these two groups have different widths (APex). To quantitatively investigate this difference and to explore the heterogeneity of pallidal neurons we carried out cell-attached and whole-cell recordings from acute slices of the rat globus pallidus (GP, the rodent homolog of the primate GPe), examining both spontaneous and evoked activity. Several parameters related to the extracellular activity were extracted in order to subdivide the population of recorded GP neurons into groups. Statistical analysis showed that the GP neurons in the rodents may be differentiated along six cellular parameters into three subgroups. Combining two of these groups allowed a better separation of the population along nine parameters. Four of these parameters (Fmax, APamp, APhw, and AHPs amplitude) form a subset, suggesting that one group of neurons may generate APs at significantly higher frequencies than the other group. This may suggest that the differences between the HFP and LFB neurons in the primate are related to fundamental underlying differences in their cellular properties.
Reduction in methicillin-resistant Staphylococcus aureus colonisation: impact of a screening and decolonisation programme

Patients in care homes are often at ‘high risk’ of being methicillin-resistant Staphylococcus aureus (MRSA) colonised. Here we report the prevalence of MRSA, the effect of MRSA screening and decolonisation in Wolverhampton care-home residents. Eighty-two care homes (1665 residents) were screened for MRSA, three times at 6-monthly intervals (referred to as phases one, two and three). Screening and decolonisation of MRSA-colonised residents led to a reduction in the prevalence of MRSA from 8.7% in phase one, 6.3% in phase 2 and 4.7% in phase three. Overall, the study suggests that care-home facilities in Wolverhampton are a significant reservoir for MRSA; screening and decolonisation has reduced the risk to residents going for procedures and has indirectly impacted on MRSA rates in the acute Trust.
SVM and Neural Network based Diagnosis of Diabetic Retinopathy

Diabetic retinopathy (DR) is an eye disease caused by the complication of diabetes and we should detect it early for effective treatment. As diabetes progresses, the vision of a patient may start deteriorate and lead to diabetic retinopathy. As a result, two groups were identified, namely nonproliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR). In this paper, to diagnose diabetic retinopathy, two models like Probabilistic Neural network (PNN) and Support vector machine (SVM) are described and their performances are compared. Experimental results show that PNN has an accuracy of 89.60% and SVM has an accuracy of 97.608 %. This infers that the SVM model outperforms the other model.
Closing the Translation Gap: Toolkit-based Implementation of Universal Decolonization in Adult Intensive Care Units Reduces Central Line-associated Bloodstream Infections in 95 Community Hospitals.

BACKGROUND Challenges exist in implementing evidence-based strategies, reaching high compliance, and achieving desired outcomes. The rapid adoption of a publicly available toolkit featuring routine universal decolonization of intensive care unit (ICU) patients may affect catheter-related bloodstream infections. METHODS Implementation of universal decolonization-treatment of all ICU patients with chlorhexidine bathing and nasal mupirocin-used a prerelease version of a publicly available toolkit. Implementation in 136 adult ICUs in 95 acute care hospitals across the United States was supported by planning and deployment tactics coordinated by a central infection prevention team using toolkit resources, along with coaching calls and engagement of key stakeholders. Operational and process measures derived from a common electronic health record system provided real-time feedback about performance. Healthcare-associated central line-associated bloodstream infections (CLABSIs), using National Healthcare Safety Network surveillance definitions and comparing the preimplementation period of January 2011 through December 2012 to the postimplementation period of July 2013 through February 2014, were assessed via a Poisson generalized linear mixed model regression for CLABSI events. RESULTS Implementation of universal decolonization was completed within 6 months. The estimated rate of CLABSI decreased by 23.5% (95% confidence interval, 9.8%-35.1%; P = .001). There was no evidence of a trend over time in either the pre- or postimplementation period. Adjusting for seasonality and number of beds did not materially affect these results. CONCLUSIONS Dissemination of universal decolonization of ICU patients was accomplished quickly in a large community health system and was associated with declines in CLABSI consistent with published clinical trial findings.
The Role of Collective Action in Enhancing Communities’ Adaptive Capacity to Environmental Risk: An Exploration of Two Case Studies from Asia

Background In this paper we examine the role of collective action in assisting rural communities to cope with and adapt to environmental risks in Nepalgunj, Nepal and Krabi Province, Thailand. Drawing upon two case studies, we explore the role of collective action in building adaptive capacity, paying particular attention to the role of social networks. Methods Data for this paper was gathered using a range of different methods across the two different studies. In Nepal semi-structured interviews were conducted with a range of stakeholders in addition to participant observation and secondary data collection. In Thailand the researchers utilised a vulnerability assessment, participatory multi-stakeholder assessment, a detailed case study and an online dialogue. Findings We make three key observations: firstly, collective action plays a significant role in enhancing adaptive capacity and hence should be more strongly considered in the development of climate change adaptation strategies; secondly, social networks are a particularly important component of collective action for the building of adaptive capacity; and thirdly, the mandate, capacity, and structure of local government agencies can influence the effectiveness of collective action, both positively and negatively. Conclusions We argue that there is an urgent need for further consideration of the different forms of collective action within community-based disaster risk management and climate change adaptation.
A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload*

Considering that the development of hepatic lesions related to iron overload diseases might be a result of abnormally expressed hepatic genes, we searched for new genes up-regulated under the condition of iron excess. By suppressive subtractive hybridization performed between livers from carbonyl iron-overloaded and control mice, we isolated a 225-base pair cDNA. By Northern blot analysis, the corresponding mRNA was confirmed to be overexpressed in livers of experimentally (carbonyl iron and iron-dextran-treated mice) and spontaneously (β2-microglobulin knockout mice) iron-overloaded mice. In addition, β2-microglobulin knockout mice fed with a low iron content diet exhibited a decrease of hepatic mRNA expression. The murine full-length cDNA was isolated and was found to encode an 83-amino acid protein presenting a strong homology in its C-terminal region to the human antimicrobial peptide hepcidin. In addition, we cloned the corresponding rat and human orthologue cDNAs. Both mouse and human genes named HEPC are constituted of 3 exons and 2 introns and are located on chromosome 7 and 19, respectively, in close proximity toUSF2 gene. In mouse and human, HEPC mRNA was predominantly expressed in the liver. During both in vivo and in vitro studies, HEPC mRNA expression was enhanced in mouse hepatocytes under the effect of lipopolysaccharide. Finally, to analyze the intracellular localization of the predicted protein, we used the green fluorescent protein chimera expression vectors. The murine green fluorescent protein-prohepcidin protein was exclusively localized in the nucleus. When the putative nuclear localization signal was deleted, the resulting protein was addressed to the cytoplasm. Taken together, our data strongly suggest that the product of the new liver-specific gene HEPCmight play a specific role during iron overload and exhibit additional functions distinct from its antimicrobial activity.
A precise and fast temperature mapping using water proton chemical shift

A new temperature measurement procedure using phase mapping was developed that makes use of the temperature dependence of the water proton chemical shift. Highly accurate and fast measurements were obtained during phantom and in vivo experiments. In the pure water phantom experiments, an accuracy of more than ± 0.5°C was obtained within a few seconds/slice using a field echo pulse sequence (TR/TE = 115/13 ms, matrix = 128 × 128, number of slices = 5). The temperature dependence of the water proton chemical shift was found to be almost the same for different materials with a chemical composition similar to living tissues (water, glucide, protein). Using this method, the temperature change inside a cat's brain was obtained with an accuracy of more than ± 1°C and an in‐plane resolution of 0.6 x 0.6 mm. The temperature measurement error was affected by several factors in the living system (B0 shifts caused by position shifts of the sample, blood flow, etc.), the position shift effect being the most serious.
Design and evaluation of a high-performance dynamically extensible router

This paper describes the design, implementation and performance of an open, high performance, dynamically extensible router under development at Washington University in St. Louis. This router supports the dynamic installation of software and hardware plug-ins in the data path of application data flows. It provides an experimental platform for research on programmable networks, protocols, router software and hardware design, network management, quality of service and advanced applications. It is designed to be flexible without sacrificing performance. It supports gigabit links and uses a scalable architecture suitable for supporting hundreds or even thousands of links. The system's flexibility makes it an ideal platform for experimental research on dynamically extensible networks that implement higher level functions in direct support of individual application sessions.
Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial.

OBJECTIVE Dietary fiber has recently received recognition for reducing the risk of developing diabetes and heart disease. The implication is that it may have therapeutic benefit in prediabetic metabolic conditions. To test this hypothesis, we investigated the effect of supplementing a high-carbohydrate diet with fiber from Konjac-mannan (KJM) on metabolic control in subjects with the insulin resistance syndrome. RESEARCH DESIGN AND METHODS We screened 278 free-living subjects between the ages of 45 and 65 years from the Canadian-Maltese Diabetes Study. A total of 11 (age 55+/-4 years, BMI 28+/-1.5 kg/m2) were recruited who satisfied the inclusion criteria: impaired glucose tolerance, reduced HDL cholesterol, elevated serum triglycerides, and moderate hypertension. After an 8-week baseline, they were randomly assigned to take either KJM fiber-enriched test biscuits (0.5 g of glucomannan per 100 kcal of dietary intake or 8-13 g/day) or wheat bran fiber (WB) control biscuits for two 3-week treatment periods separated by a 2-week washout. The diets were isoenergetic, metabolically controlled, and conformed to National Cholesterol Education Program Step 2 guidelines. Serum lipids, glycemic control, and blood pressure were the outcome measures. RESULTS Decreases in serum cholesterol (total, 12.4+/-3.1%, P<0.004; LDL, 22+/-3.9%, P<0.002; total/HDL ratio, 15.2+/-3.4%, P<0.003; and LDL/HDL ratio, 22.2+/-4.1%, P< 0.002), apolipoprotein (apo) B (15.1+/-4.3%, P<0.0004), apo B/A-1 ratio (13.1+/-3.4%, P< 0.0003), and serum fructosamine (5.2+/-1.4%, P<0.002) were observed during KJM treatment compared with WB-control. Fasting blood glucose, insulin, triglycerides, HDL cholesterol, and body weight remained unchanged. CONCLUSIONS A diet rich in high-viscosity KJM improves glycemic control and lipid profile, suggesting a therapeutic potential in the treatment of the insulin resistance syndrome.
Multiple Source Adaptation and the Rényi Divergence

This paper presents a novel theoretical study of the general problem of multiple source adaptation using the notion of Renyi divergence. Our results build on our previous work [12], but significantly broaden the scope of that work in several directions. We extend previous multiple source loss guarantees based on distribution weighted combinations to arbitrary target distributions P, not necessarily mixtures of the source distributions, analyze both known and unknown target distribution cases, and prove a lower bound. We further extend our bounds to deal with the case where the learner receives an approximate distribution for each source instead of the exact one, and show that similar loss guarantees can be achieved depending on the divergence between the approximate and true distributions. We also analyze the case where the labeling functions of the source domains are somewhat different. Finally, we report the results of experiments with both an artificial data set and a sentiment analysis task, showing the performance benefits of the distribution weighted combinations and the quality of our bounds based on the Renyi divergence.
A Neural Basis for Percept Stabilization in Binocular Rivalry

When the same visual input has conflicting interpretations, conscious perception can alternate spontaneously between each competing percept. Surprisingly, such bistable perception can be stabilized by intermittent stimulus removal, suggesting the existence of perceptual memory across interruptions in stimulation. The neural basis of such a process remains unknown. Here, we studied binocular rivalry, one type of bistable perception, in two linked experiments in human participants. First, we showed, in a behavioral experiment using binocular rivalry between face and grating stimuli, that the stabilizing effect of stimulus removal was specific to perceptual alternations evoked by rivalry, and did not occur following physical alternations in the absence of rivalry. We then used functional magnetic resonance imaging to measure brain activity in a variable delay period of stimulus removal. Activity in the fusiform face area during the delay period following removal of rivalrous stimuli was greater following face than grating perception, whereas such a difference was absent during removal of non-rivalrous stimuli. Moreover, activity in areas of fronto-parietal regions during the delay period correlated with the degree to which individual participants tended to experience percept stabilization. Our findings suggest that percept-related activity in specialized extrastriate visual areas help to stabilize perception during perceptual conflict, and that high-level mechanisms may determine the influence of such signals on conscious perception.
Unsupervised Semantic Role Induction with Global Role Ordering

We propose a probabilistic generative model for unsupervised semantic role induction, which integrates local role assignment decisions and a global role ordering decision in a unified model. The role sequence is divided into intervals based on the notion of primary roles, and each interval generates a sequence of secondary roles and syntactic constituents using local features. The global role ordering consists of the sequence of primary roles only, thus making it a partial ordering.
Behavior of metals in soils

Metals added to soil will normally be retained at the soil surface. Movement of metals into other environmental compartments, i.e. groundwater, surface water, or the atmosphere, should be minimal as long as the retention capacity of the soil is not exceeded. The extent of movement of a metal in the soil system is intimately related to the solution and surface chemistry of the soil and to the specific properties of the metal and associated waste matrix. The retention mechanisms for metals added to soil include absorption of the metal by the soil solid surfaces and precipitation. In addition to soil properties, consideration must be given to the type of metal and its concentration and to the presence of competing ions, complexing ligands, and the pH and redox potential of the soil-waste matrix. Because of the wide range of soil characteristics and various forms by which metals can be added to soil, evaluating the extent of metal retention by a soil is site/soil/waste specific. Laboratory methods for evaluating the behavior of metals in soils are available in the literature. Thermodynamic equilibrium computer models are also available to assist with the evaluation. The advantages and disadvantages of some of the available proceduresmore » and models have been presented in the document. « less
On the Design of Relay Selection Strategies in Regenerative Cooperative Networks with Outdated CSI

Opportunistic relay selection is considered as an efficient approach to implement cooperative communication in multi-relay cooperative networks owing to its low implementation complexity. However, due to channel fluctuations, the channel state information (CSI) employed in relay selection process may differ from the exact CSI in data forwarding, in other words, the CSI is outdated. Addressing this issue, this paper focuses on the design of relay selection strategies in decode-and-forward (DF) cooperative networks with outdated CSIs being available in relay judgement, as well as their performance analysis. We resort to two main cases, 1) only outdated CSIs are available in relay selection process; 2) both outdated CSIs and statistical channel information are available in selection procedure, and propose three different relay selection schemes. The expressions of outage probability are derived, and asymptotic analysis in high SNR region is also carried out. Simulation results are finally provided, which not only validate our theoretical analysis, but also shed light on the way of designing relay selection strategies in various scenarios.
Symptoms of anxiety and depression in Estonian medical students with sleep problems

High emotional stress in medical students has been observed in many studies. Our aim in this article was to assess the prevalence of symptoms of anxiety and depression among Estonian medical students and to find relationships between sleep complaints and emotional symptoms. The study group consisted of 413 medical students, ages 19–33 years, at the University of Tartu. Each was asked to complete two questionnaires: the Emotional State Questionnaire (EST‐Q), containing 28 questions, and the Questionnaire on Sleep and Daytime Habits, with 25 questions. The anxiety and depression subscales from the EST‐Q were applied. From the study group, 21.9% students had symptoms of anxiety, and 30.6% had symptoms of depression. The frequency of anxiety and depressive symptoms was higher in females. In regression and multiple regression analysis, we determined which sleep problems were related to emotional symptoms. The associations were different for men and women. In women, anxiety remained significantly related to waking up because of nightmares and feeling tired in the morning; depressive symptoms were related to difficulties in getting to sleep at night, waking up because of nightmares and nocturnal eating habits, daytime sleepiness, and sleepiness during school lessons. In men, significant relations were clear only for depression: difficulties in falling asleep at night before an exam and subjective sleep quality. The study demonstrated that a high percentage of medical students had emotional symptoms. We found that some sleep problems indicated underlying symptoms of anxiety and depression. Depression and Anxiety 23:250–256, 2006. © 2006 Wiley‐Liss, Inc.