Miracle-dz/UniFAR-FTUs huggingface dataset:
Measles virus antibody responses in children randomly assigned to receive standard-titer edmonston-zagreb measles vaccine at 4.5 and 9 months of age, 9 months of age, or 9 and 18 months of age.

The World Health Organization recommends administration of measles vaccine (MV) at age 9 months in low-income countries. We tested the measles virus antibody response at 4.5, 9, 18, and 24 months of age for children randomly assigned to receive standard-titer Edmonston-Zagreb MV at 4.5 and 9 months, at 9 months, or at 9 and 18 months of age. At 4.5 months of age, 75% had nonprotective measles virus antibody levels. Following receipt of MV at 4.5 months of age, 77% (316/408) had protective antibody levels at 9 months of age; after a second dose at 9 months of age, 97% (326/337) had protective levels at 24 months of age. In addition, the response at both 9 and 24 months of age was inversely correlated with the antibody level at receipt of the first dose of MV, and the second dose of MV, received at 9 months of age, provided a significant boost in antibody level to children who had low antibody levels. In the group of 318 children who received MV at 9 months of age, with or without a second dose at 18 months of age, 99% (314) had protective levels at 24 months of age. The geometric mean titer at 24 months of age was significantly lower in the group that received MV at 4.5 and 9 months of age than in the group that received MV at 9 months of age (P = .0001). In conclusion, an early 2-dose MV schedule was associated with protective measles virus antibody levels at 24 months of age in nearly all children. Clinical Trials Registration. NCT00168558.
Towards inter-vehicle communication strategies for platooning support

Platooning, the idea of cars autonomously following their leaders to form a road train, has huge potentials to improve traffic flow efficiency and, most importantly, road traffic safety. Wireless communication is a fundamental building block - it is needed to manage and to maintain the platoons. To keep the system stable, strict constraints in terms of update frequency and reliability must be met. We developed communication strategies by explicitly taking into account the requirements of the controller, exploiting synchronized communication slots as well as transmit power adaptation. The proposed approaches are compared to two state of the art adaptive beaconing protocols that have been designed for generic message dissemination. Our simulation models have been parametrized and validated by means of real-world experiments. We clearly show how taking into account specific requirements can be extremely beneficial even in very crowded freeway scenarios.
The Inverted Multi-Index

A new data structure for efficient similarity search in very large datasets of high-dimensional vectors is introduced. This structure called the inverted multi-index generalizes the inverted index idea by replacing the standard quantization within inverted indices with product quantization. For very similar retrieval complexity and pre-processing time, inverted multi-indices achieve a much denser subdivision of the search space compared to inverted indices, while retaining their memory efficiency. Our experiments with large datasets of SIFT and GIST vectors demonstrate that because of the denser subdivision, inverted multi-indices are able to return much shorter candidate lists with higher recall. Augmented with a suitable reranking procedure, multi-indices were able to significantly improve the speed of approximate nearest neighbor search on the dataset of 1 billion SIFT vectors compared to the best previously published systems, while achieving better recall and incurring only few percent of memory overhead.
Consistent resting-state networks across healthy subjects

Functional MRI (fMRI) can be applied to study the functional connectivity of the human brain. It has been suggested that fluctuations in the blood oxygenation level-dependent (BOLD) signal during rest reflect the neuronal baseline activity of the brain, representing the state of the human brain in the absence of goal-directed neuronal action and external input, and that these slow fluctuations correspond to functionally relevant resting-state networks. Several studies on resting fMRI have been conducted, reporting an apparent similarity between the identified patterns. The spatial consistency of these resting patterns, however, has not yet been evaluated and quantified. In this study, we apply a data analysis approach called tensor probabilistic independent component analysis to resting-state fMRI data to find coherencies that are consistent across subjects and sessions. We characterize and quantify the consistency of these effects by using a bootstrapping approach, and we estimate the BOLD amplitude modulation as well as the voxel-wise cross-subject variation. The analysis found 10 patterns with potential functional relevance, consisting of regions known to be involved in motor function, visual processing, executive functioning, auditory processing, memory, and the so-called default-mode network, each with BOLD signal changes up to 3%. In general, areas with a high mean percentage BOLD signal are consistent and show the least variation around the mean. These findings show that the baseline activity of the brain is consistent across subjects exhibiting significant temporal dynamics, with percentage BOLD signal change comparable with the signal changes found in task-related experiments.
Synthesis and Conformational Study of a Novel Macrocyclic Chiral(Salen) ligand and its Uranyl and Mn Complexes

A novel chiral macrocyclic ligand incorporating a chiral salen moiety into a framework containing two biphenyl units was synthesized. Structural properties and conformational aspects of the free ligand and an UO2 complex were studied by using NMR spectroscopy in solution and MM calculations. The Mn(III) complex was tested as catalyst in enantioselective oxidation of prochiral unfunctionalized olefins to the corresponding optically active epoxides under very mild conditions.
Oblivious Cooperation of Wireless Colocated Transmitters

We address a scenario where a source sends information to a remote destination and where a relay terminal is occasionally present in close proximity to the source, but without the source's knowledge. We assume independent block fading channels from the source and the occasional relay to the destination, while the channel between the source and the relay is assumed additive Gaussian, due to their mutual proximity. The focus is on cooperative schemes which make efficient use of the relay when it is present, and maintain single user optimality when it is absent. One such scheme is shown to be block Markov decode-and-forward involving correlated transmissions of the source and the relay. The optimal correlation for this scheme is found by optimizing the outage performance of a 2X1 multiple-input single-output (MISO) link under certain constraints. Finally, quantization schemes involving various levels of side information are discussed.
Faddeev study of heavy-baryon spectroscopy

We investigate the structure of heavy baryons containing a charm or a bottom quark. We employ a constituent quark model successful in the description of the baryon–baryon interaction which is consistent with the light-baryon spectra. We solve exactly the three-quark problem by means of the Faddeev method in momentum space. Heavy-baryon spectrum shows a manifest compromise between perturbative and nonperturbative contributions. The flavour dependence of the one-gluon exchange is analysed. We assign quantum numbers to some already observed resonances, and we predict the first radial and orbital excitations of all states with J = 1/2 or 3/2. We combine our results with heavy-quark symmetry and lowest order SU(3) symmetry breaking to predict the masses and quantum numbers of six still non-measured ground-state beauty baryons.
Self-Duality and Maximally Helicity Violating QCD Amplitudes

I review some recent work that describes the close analogy between self-dual Yang–Mills amplitudes and QCD amplitudes with external gluons of positive helicity. This analogy is carried at tree level for amplitudes with two external quarks and up to one-loop for amplitudes involving only external gluons.
Antineoplastic Agents: the Importance of Sequence of Administration'

Flavopiridol, the first potent cyclin-dependent kinase inhibitor to un dergo clinical trials as an antineoplastic agent in the United States, has attracted considerable attention because of its unique cellular targets and its ability to kill noncycling tumor cells in vitro.To better understand how flavopiridol might be used clinically, the present study used colony. forming assays to examine the cytotoxicity resulting from combining flavopiridol with eight other antineoplastic agents in four different ad ministration schedules in A549 human non-small cell lung carcinoma cells in vitro. Cytotoxic synergy, as assessed by the median effect method, resulted when flavopiridol was combined with seven of the eight tested antineoplastic agents but was highly dependent upon administration schedule. Cisplatin was the only agent that resulted in sequence-indepen dent synergywhencombinedwith flavopiridol.For paclitaxel,cytarabine, topotecan, doxorubicin, and etoposide, synergy was more pronounced when the agents were administered before flavopiridol rather than con comitant with or following flavopiridol. Examination suggested that this sequence dependence reflected arrest of cells in G1 and G2 phases of the cell cycle during and for 24 h following flavopiridol treatment. Interest htgly, 48â€ " 72 h after flavopiridol removal, the fraction of surviving cells in S phase increased 2â€ " 3-fold relative to untreated controls. Consistent with these results, administration of flavopiridol for 24 h followed 3 days later by exposure to an S phase-active agent (cytarabine or 5-fluorouradil) resulted in a highly synergistic interaction. These results highlight the importance of administration schedule when combining flavopindol with other agents and provide a starting point for examining the effect of flavopiridol in drug combinationsin vivo.
Traversal time for weakly synchronized CAN bus

Scheduling frames with offsets has been shown in the literature to be very beneficial for reducing response times in realtime networks because it allows the workload to be better spread over time and thus to reduce peaks of load. Maintaining a global synchronization amongst the stations induces substantial overhead and complexity in networks not providing a global time service such as CAN. Indeed, on CAN, no global clock is implemented in practice and each station possesses its own local clock. Without a global clock, the de-synchronization between the streams of frames created by offsets remains local to each station. The first contribution of this work is to show that important gains with respect to the communication latencies, around 40% in our experiments, can be achieved if we implement bounded clock desynchronization, also refered to as bounded phases, between the stations. The second contribution of this work is to provide a set of network-calculus based timing analyses to handle systems with bounded phases and compare their performances.
Compressive Sampling of EEG Signals with Finite Rate of Innovation

Analyses of electroencephalographic signals and subsequent diagnoses can only be done effectively on long term recordings that preserve the signals' morphologies. Currently, electroencephalographic signals are obtained at Nyquist rate or higher, thus introducing redundancies. Existing compression methods remove these redundancies, thereby achieving compression. We propose an alternative compression scheme based on a sampling theory developed for signals with a finite rate of innovation (FRI) which compresses electroencephalographic signals during acquisition. We model the signals as FRI signals and then sample them at their rate of innovation. The signals are thus effectively represented by a small set of Fourier coefficients corresponding to the signals' rate of innovation. Using the FRI theory, original signals can be reconstructed using this set of coefficients. Seventy-two hours of electroencephalographic recording are tested and results based on metrices used in compression literature and morphological similarities of electroencephalographic signals are presented. The proposed method achieves results comparable to that of wavelet compression methods, achieving low reconstruction errors while preserving the morphologiies of the signals. More importantly, it introduces a new framework to acquire electroencephalographic signals at their rate of innovation, thus entailing a less costly low-rate sampling device that does not waste precious computational resources.
What’s Wrong With the ‘War on Obesity?’ A Narrative Review of the Weight-Centered Health Paradigm and Development of the 3C Framework to Build Critical Competency for a Paradigm Shift

Discourse about health that focuses predominantly on body weight is referred to as the weight-centered health paradigm (WCHP). In recent years, there has been a significant increase in critical analysis of the WCHP. This has resulted in arguments for a paradigm shift away from focusing on weight and focusing instead on health and well-being. The aim of this study was to identify, critique, and synthesize the values, claims, and assumptions of the WCHP and to develop a framework to be used as a heuristic for building competency to critique the WCHP. Qualitative content analysis of the literature was used to identify themes, relationships between themes, and structure of the framework. The resulting WCHP 3C Framework encompasses the context, critiques, and consequences of the WCHP. The context includes the promulgators and tenets of the WCHP. Critiques of the WCHP raise ideological, empirical, and technical concerns. Consequences of the WCHP include an enhanced adipophobicogenic environment, reduced health and well-being, and reduced quality of life. If used as a heuristic to enhance critical competence, the WCHP 3C Framework may help contribute to a paradigm shift in weight science.
Phase space geometry and slow dynamics

We describe a non-Arrhenius mechanism for the slowing down of dynamics that is inherent to the high dimensionality of the phase space. We show that such a mechanism is at work both in a family of mean-field spin-glass models without any domain structure and in the case of ferromagnetic domain growth. The marginality of spin-glass dynamics, as well as the existence of a `quasi-equilibrium regime' can be understood within this scenario. We discuss the question of ergodicity in an out-of equilibrium situation.
The effect of background information on object identification

The Role of Background on Object Identification (September 1987) Susan J. Boyce B.S., Ursinus College M.S., University of Massachusetts Directed by: Professor Alexander Pollatsek This thesis examines the role that scene backgrounds play in object identification. Previous research has indicated that objects located in a coherent scene are easier to identify. This research employed the brief presentation method used In previous research on scene perception. Experiment 1 Indicates that objects are more difficult to identify when they are located in an "episodically" inconsistent background. Experiment 2 demonstrates that the degree to which non-cued (cohort) objects are consistent with the target object has no effect on this object identification task. Experiment 3 shows that consistent episodic background information facilitates object identification and Inconsistent episodic background information does not interfere. The results of these studies indicate that models of scene perception will have to be mod i f i ed .
Undressing the Words: Prevalence of Profanity, Misogyny, Violence, and Gender Role References in Popular Music from 2006-2016

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Color priming in pop-out search depends on the relative color of the target

In visual search for pop-out targets, search times are shorter when the target and non-target colors from the previous trial are repeated than when they change. This priming effect was originally attributed to a feature weighting mechanism that biases attention toward the target features, and away from the non-target features. However, more recent studies have shown that visual selection is strongly context-dependent: according to a relational account of feature priming, the target color is always encoded relative to the non-target color (e.g., as redder or greener). The present study provides a critical test of this hypothesis, by varying the colors of the search items such that either the relative color or the absolute color of the target always remained constant (or both). The results clearly show that color priming depends on the relative color of a target with respect to the non-targets but not on its absolute color value. Moreover, the observed priming effects did not change over the course of the experiment, suggesting that the visual system encodes colors in a relative manner from the start of the experiment. Taken together, these results strongly support a relational account of feature priming in visual search, and are inconsistent with the dominant feature-based views.
Financial Deepening and Economic Development of Nigeria: An Empirical Investigation

This empirical study examined financial deepening and economic development in Nigeria between 1986 and 2007. The central focus is that a high level of financial deepening is a necessary condition for accelerating growth in an economy. This is because of the central role of the financial system in mobilizing savings and allocating same for the development process. The study made use of secondary data, sourced for a period of 22 years. We specified nine explanatory variables for the study based on theoretical underpinnings. We sought to establish a relationship between these variables and financial deepening index. The two stages least squares analytical framework was used in the analysis. A trend analysis was also done in the study. At the end of the study, we found that financial deepening index is low in Nigeria over the years. We also found that the nine explanatory variables, as a whole were useful and had a statistical relationship with financial deepening. But four of the variables; lending rates, financial savings ratio, cheques/GDP ratio and the deposit money banks/GDP ratio had a significant relationship with financial deepening. We concluded that: the financial system has not sustained an effective financial intermediation, especially credit allocation and a high level of monetization of the economy. Thus the regulatory framework should be restructured to ensure good risk management, corporate governance and stemming systemic crisis in the system.
Heat Shock Protein 60 in Eggs Specifically Induces Tregs and Reduces Liver Immunopathology in Mice with Schistosomiasis Japonica

Background Parasitic helminths need to suppress the host immune system to establish chronic infections. Paradoxically, immunosuppression induced by the worm also benefits the host by limiting excessive inflammation and tissue damage, which remains the major cause leading to serious morbidity and mortality. Regulatory T cells (Tregs) are key immune regulators of this mutualism. The successive rise in Tregs during schistosome infection plays a critical role in immunoregulation. We and others previously showed that Schistosoma japonicum (S. japonicum) egg antigens (SEA) induce Tregs both in vitro and in vivo. In addition, we identified that SjHSP60 derived from SEA significantly induces Tregs in vivo and in vitro. However, the contribution of SjHSP60 in SEA to Treg induction and the related mechanisms of the Treg induction have not yet been identified. Methodology/Principal Findings In this study, we showed that S. japonicum stress protein HSP60 (SjHSP60) was constitutively and extensively expressed in eggs of S. japonicum. SjHSP60 specially induced Tregs in vivo and in vitro without inducing other CD4+ T sub-populations including Th1, Th2 and Th17 cells. Furthermore, we showed that the SjHSP60-depleted SEA almost lost the ability in vitro and displayed a significant impaired ability to induce Tregs in vivo. Finally, our study illustrated that the mechanisms of SjHSP60-mediated induction of Tregs are through both conversion of CD4+CD25- T cells into CD4+CD25+Foxp3+ Tregs and expansion of preexisting CD4+CD25+Foxp3+ Tregs in a TLR4-dependent manner. Conclusions/Significance Collectively, our findings identify SjHSP60 as a major parasitic contributor of Treg induction in S. japonicum egg antigens, which not only contributes to the better understanding of the mechanism of immunoregulation during helminth infection, but also suggests its potential as a therapeutic target for control of immunopathology, allergic and autoimmune diseases.
Safety and immunogenicity of live attenuated influenza reassortant H5 vaccine (phase I–II clinical trials)

Objective Our studies aimed to evaluate in clinical trials the safety and immunogenicity of an H5 live influenza vaccine candidate obtained using classical reassortment techniques from a low pathogenicity avian influenza (LPAI) A/Duck/Potsdam/1402‐6/86(H5N2) virus and the cold‐adapted (ca) donor strain A/Leningrad/134/17/57(H2N2).
Multisensory Part-based Representations of Objects in Human Lateral Occipital Cortex

Abstract The format of high-level object representations in temporal-occipital cortex is a fundamental and as yet unresolved issue. Here we use fMRI to show that human lateral occipital cortex (LOC) encodes novel 3-D objects in a multisensory and part-based format. We show that visual and haptic exploration of objects leads to similar patterns of neural activity in human LOC and that the shared variance between visually and haptically induced patterns of BOLD contrast in LOC reflects the part structure of the objects. We also show that linear classifiers trained on neural data from LOC on a subset of the objects successfully predict a novel object based on its component part structure. These data demonstrate a multisensory code for object representations in LOC that specifies the part structure of objects.
Design and Analysis of Relay-aided Broadcast using Binary Network Codes

We consider a base-station broadcasting a set of order-insensitive packets to a user population over packet-erasure channels. To improve efficiency we propose relay-aided transmission using instantaneously-decodable binary network coding. The proposed coding schemes have the benefits of minimal decoding delay and low complexity. We further analyze the performance of the resulting broadcast schemes, and show that significant improvements in transmission efficiency are obtained as compared to previously proposed ARQ and network-coding-based schemes.