Miracle-dz/UniFAR-FTUs huggingface dataset:
Collective Reputation, Professional Regulation and Franchising

Collective reputation and its associated free-rider problem have been invoked to justify state licensing of professions and to explain the incidence of franchising. We examine the conditions under which it is possible to create a Pareto-improving collective reputation among groups of heterogeneous producers. If the regulator or franchisor cannot credibly commit to high quality then a common reputation can be created only if the groups are not too different and if marginal cost is declining. High cost groups benefit most from forming a common regime.
Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea

Given the current absence of specific drugs or vaccines for Ebola virus disease (EVD), rapid, sensitive, and reliable diagnostic methods are required to stem the transmission chain of the disease. We have developed a rapid detection assay for Zaire ebolavirus based on reverse transcription-loop-mediated isothermal amplification (RT-LAMP) and coupled with a novel portable isothermal amplification and detection platform. The RT-LAMP assay is based on primer sets that target the untranscribed trailer region or nucleoprotein coding region of the viral RNA. The test could specifically detect viral RNAs of Central and West African Ebola virus strains within 15 minutes with no cross-reactivity to other hemorrhagic fever viruses and arboviruses, which cause febrile disease. The assay was evaluated using a total of 100 clinical specimens (serum, n = 44; oral swab, n = 56) collected from suspected EVD cases in Guinea. The specificity of this diagnostic test was 100% for both primer sets, while the sensitivity was 100% and 97.9% for the trailer and nucleoprotein primer sets, respectively, compared with a reference standard RT-PCR test. These observations suggest that our diagnostic assay is useful for identifying EVD cases, especially in the field or in settings with insufficient infrastructure.
Generalized Odds Ratios for Ordinal Data

We consider properties of the ordinal measure of association defined by the ratio of the proportions of concordant and discordant pairs. For 2 x 2 cross-classification tables, the measure simplifies to the odds ratio. The generalized measure can be used to summarize the difference between two stochastically ordered distributions of an ordinal categorical variable. The ratio of its values for two groups constitutes an odds ratio defined in terms of pairs of observations. Unlike the odds ratio measures proposed by Clayton (1974, Bionxetrika 61, 525-531) for similar purposes, this measure is not linked to specific model assumptions and hence it is more widely applicable as a descriptive measure.
An African success: the case of conservation agriculture in Zimbabwe

This paper highlights the limiting factors of agricultural production in Zimbabwe and presents conservation agriculture (CA) as a potential solution to address many of these challenges. CA, based on the three principles of minimum soil disturbance, crop residue retention and crop rotations, targets low soil fertility, moisture deficits and low management standards through the use of soil-fertility-enhancing technologies (precision fertilizer application, crop rotations, sequencing and interactions), improved moisture use efficiency and higher standards of agronomic management practices. The paper also explains the role of CA in natural resource conservation as increasing productivity will reduce the land under crop production and increase the area under natural vegetation. Trends in the development of CA in the past five years and its current status in the country are explained, with the roles of different stakeholders outlined. Evidence on the impact of CA on both food security and the environment is presented. In conclusion, the paper looks at the various factors that may affect the spread of CA to different agro-ecological zones in the country.
Greater accordance with the Dietary Approaches to Stop Hypertension dietary pattern is associated with lower diet-related greenhouse gas production but higher dietary costs in the United Kingdom12

Background: The Dietary Approaches to Stop Hypertension (DASH) diet is a proven way to prevent and control hypertension and other chronic disease. Because the DASH diet emphasizes plant-based foods, including vegetables and grains, adhering to this diet might also bring about environmental benefits, including lower associated production of greenhouse gases (GHGs). Objective: The objective was to examine the interrelation between dietary accordance with the DASH diet and associated GHGs. A secondary aim was to examine the retail cost of diets by level of DASH accordance. Design: In this cross-sectional study of adults aged 39–79 y from the European Prospective Investigation into Cancer and Nutrition–Norfolk, United Kingdom cohort (n = 24,293), dietary intakes estimated from food-frequency questionnaires were analyzed for their accordance with the 8 DASH food and nutrient-based targets. Associations between DASH accordance, GHGs, and dietary costs were evaluated in regression analyses. Dietary GHGs were estimated with United Kingdom-specific data on carbon dioxide equivalents associated with commodities and foods. Dietary costs were estimated by using national food prices from a United Kingdom–based supermarket comparison website. Results: Greater accordance with the DASH dietary targets was associated with lower GHGs. Diets in the highest quintile of accordance had a GHG impact of 5.60 compared with 6.71 kg carbon dioxide equivalents/d for least-accordant diets (P < 0.0001). Among the DASH food groups, GHGs were most strongly and positively associated with meat consumption and negatively with whole-grain consumption. In addition, higher accordance with the DASH diet was associated with higher dietary costs, with the mean cost of diets in the top quintile of DASH scores 18% higher than that of diets in the lowest quintile (P < 0.0001). Conclusions: Promoting wider uptake of the DASH diet in the United Kingdom may improve population health and reduce diet-related GHGs. However, to make the DASH diet more accessible, food affordability, particularly for lower income groups, will have to be addressed.
Arterial Stiffness Is Associated with Peripheral Sensory Neuropathy in Diabetes Patients in Ghana

Objective Peripheral sensory neuropathy (PSN) is among microvascular complications of diabetes that make patients prone to ulceration and amputation. Arterial stiffness is a predictor of cardiovascular diseases and microvascular complications associated with diabetes. We investigated the association between PSN and arterial stiffness, measured as aortic pulse wave velocity (PWVao) and cardio-ankle vascular index (CAVI). Method In a case-control design, arterial stiffness was measured in 240 diabetes patients and 110 nondiabetic control. Large-fibre nerve function was assessed by vibration perception threshold (VPT) using a neurothesiometer. PSN was defined as the VPT > 97.5th percentile from age- and gender-adjusted models in nondiabetic controls. Results The overall prevalence of PSN was 16.6% in the entire study participants. Compared to non-PSN participants, PSN patients had higher levels of PWVao (9.5 ± 1.7 versus 8.7 ± 1.2 m/s, p = 0.016) and CAVI (8.4 ± 1.3 versus 7.6 ± 1.1, p = 0.001). In multiple regression models, VPT was associated with PWVao (β = 0.14, p = 0.025) and CAVI (β = 0.12, p = 0.04). PSN patients had increased odds of CAVI (OR = 1.51 (1.02–2.4), p = 0.043), but not PWVao (OR = 1.25 (0.91–1.71), p = 0.173). Conclusion PWVao and CAVI were associated with VPT and PSN in diabetes patients in Ghana. Patients having PSN have increased odds of CAVI, independent of other conventional risk factors.
Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition

The canonical Wnt signaling pathway is critical for skeletal development and maintenance, but the precise roles of the individual Wnt co-receptors, Lrp5 and Lrp6, that enable Wnt signals to be transmitted in osteoblasts remain controversial. In these studies, we used Cre-loxP recombination, in which Cre-expression is driven by the human osteocalcin promoter, to determine the individual contributions of Lrp5 and Lrp6 in postnatal bone acquisition and osteoblast function. Mice selectively lacking either Lrp5 or Lrp6 in mature osteoblasts were born at the expected Mendelian frequency but demonstrated significant reductions in whole-body bone mineral density. Bone architecture measured by microCT revealed that Lrp6 mutant mice failed to accumulate normal amounts of trabecular bone. By contrast, Lrp5 mutants had normal trabecular bone volume at 8 weeks of age, but with age, these mice also exhibited trabecular bone loss. Both mutants also exhibited significant alterations in cortical bone structure. In vitro differentiation was impaired in both Lrp5 and Lrp6 null osteoblasts as indexed by alkaline phosphatase and Alizarin red staining, but the defect was more pronounced in Lrp6 mutant cells. Mice lacking both Wnt co-receptors developed severe osteopenia similar to that observed previously in mice lacking β-catenin in osteoblasts. Likewise, calvarial cells doubly deficient for Lrp5 and Lrp6 failed to form osteoblasts when cultured in osteogenic media, but instead attained a chondrocyte-like phenotype. These results indicate that expression of both Lrp5 and Lrp6 are required within mature osteoblasts for normal postnatal bone development.
March AB, March AB1: new March tests for unlinked dynamic memory faults

Among the different types of algorithms proposed to test static random access memories (SRAMs), March tests have proven to be faster, simpler and regularly structured. New memory production technologies introduce new classes of faults usually referred to as dynamic memory faults. A few March tests for dynamic fault, with different fault coverage, have been published. In this paper, we propose new March tests targeting unlinked dynamic faults with lower complexity than published ones. Comparison results show that the proposed March tests provide the same fault coverage of the known ones, but they reduce the test complexity, and therefore the test time
When, Where and How Osteoporosis-Associated Fractures Occur: An Analysis from the Global Longitudinal Study of Osteoporosis in Women (GLOW)

Objective To examine when, where and how fractures occur in postmenopausal women. Methods We analyzed data from the Global Longitudinal Study of Osteoporosis in Women (GLOW), including women aged ≥55 years from the United States of America, Canada, Australia and seven European countries. Women completed questionnaires including fracture data at baseline and years 1, 2 and 3. Results Among 60,393 postmenopausal women, 4122 incident fractures were reported (86% non-hip, non-vertebral [NHNV], 8% presumably clinical vertebral and 6% hip). Hip fractures were more likely to occur in spring, with little seasonal variation for NHNV or spine fractures. Hip fractures occurred equally inside or outside the home, whereas 65% of NHNV fractures occurred outside and 61% of vertebral fractures occurred inside the home. Falls preceded 68–86% of NHNV and 68–83% of hip fractures among women aged ≤64 to ≥85 years, increasing with age. About 45% of vertebral fractures were associated with falls in all age groups except those ≥85 years, when only 24% occurred after falling. Conclusion In this multi-national cohort, fractures occurred throughout the year, with only hip fracture having a seasonal variation, with a higher proportion in spring. Hip fractures occurred equally within and outside the home, spine fractures more often in the home, and NHNV fractures outside the home. Falls were a proximate cause of most hip and NHNV fractures. Postmenopausal women at risk for fracture need counseling about reducing potentially modifiable fracture risk factors, particularly falls both inside and outside the home and during all seasons of the year.
The Local Discontinuous Galerkin Method for Time-Dependent Convection-Diffusion Systems

In this paper, we study the local discontinuous Galerkin (LDG) methods for nonlinear, time-dependent convection-diffusion systems. These methods are an extension of the Runge--Kutta discontinuous Galerkin (RKDG) methods for purely hyperbolic systems to convection-diffusion systems and share with those methods their high parallelizability, high-order formal accuracy, and easy handling of complicated geometries for convection-dominated problems. It is proven that for scalar equations, the LDG methods are L2-stable in the nonlinear case. Moreover, in the linear case, it is shown that if polynomials of degree k are used, the methods are kth order accurate for general triangulations; although this order of convergence is suboptimal, it is sharp for the LDG methods. Preliminary numerical examples displaying the performance of the method are shown.
Large scale, highly efficient and self-powered UV photodetectors enabled by all-solid-state n-TiO2 nanowell/p-NiO mesoporous nanosheet heterojunctions

Self-powered UV photodetectors (PDs) functioning without any power supply are urgently needed in modern optoelectronic devices from the viewpoint of being energy saving, portable and miniature. In this work, we report a novel heterojunction structure on a large scale based on n-type TiO2 nanowells and p-type NiO mesoporous nanosheets in an economic route. The novel synthesis strategy using thin-layers of TiO2 nanowells instead of conventional anodic nanotube geometry enables faster charge carrier transport through a shorter diffusion pathway along the lateral direction; and the flower-like morphology of NiO nanosheets guarantees the interfacial active reaction sites to UV light exposure, which takes great advantages of the p–n junction area to enhance the generation of electron–hole pairs. The hybrid PD performed in a self-powered mode is carefully explored which shows an enhanced photoresponse including good responsivity, excellent wavelength selectivity and high stability. This work presented here opens up new avenues for developing high-performance energy-efficient devices economically with a large area.
Enjoying the Quiet Life? Corporate Governance and Managerial Preferences

Much of our understanding of corporations builds on the idea that managers, when they are not closely monitored, will pursue goals that are not in shareholders’ interests. But what goals would managers pursue? This paper uses variation in corporate governance generated by state adoption of antitakeover laws to empirically map out managerial preferences. We use plant‐level data and exploit a unique feature of corporate law that allows us to deal with possible biases associated with the timing of the laws. We find that when managers are insulated from takeovers, worker wages (especially those of white‐collar workers) rise. The destruction of old plants falls, but the creation of new plants also falls. Finally, overall productivity and profitability decline in response to these laws. Our results suggest that active empire building may not be the norm and that managers may instead prefer to enjoy the quiet life.
Childhood adversity and psychosis: generalised or specific effects?

Background. This study examines relationships between childhood adversity and the presence of characteristic symptoms of schizophrenia. It was hypothesised that total adversity exposures would be significantly higher in individuals exhibiting these symptoms relative to patients without. Recent proposals that differential associations exist between specific psychotic symptoms and specific adversities was also tested, namely: sexual abuse and hallucinations, physical abuse and delusions, and fostering/adoption and delusions. Method. Data were collected through auditing 251 randomly selected medical records, drawn from adult patients in New Zealand community mental health centres. Information was extracted on presence and subtype of psychotic symptoms and exposure to ten types of childhood adversity, including five types of abuse and neglect. Results. Adversity exposure was significantly higher in patients experiencing hallucinations in general, voice hearing, command hallucinations, visions, delusions in general, paranoid delusions and negative symptoms than in patients without these symptoms. There was no difference in adversity exposure in patients with and without tactile/olfactory hallucinations, grandiose delusions or thought disorder. Indication of a dose–response relationship was detected, in that total number of adversities significantly predicted total number of psychotic symptoms. Although fostering/adoption was associated with paranoid delusions, the hypothesised specificity between sexual abuse and hallucinations, and physical abuse and delusions, was not found. The two adversities showing the largest number of associations with psychotic symptoms were poverty and being fostered/adopted. Conclusions. The current data are consistent with a model of global and cumulative adversity, in which multiple exposures may intensify psychosis risk beyond the impact of single events. Implications for clinical intervention are discussed.
In-Band Full Duplex Broadband Power Line Communications

In this paper, we introduce in-band full duplexing (IBFD) for broadband power line communication (BB-PLC) systems. Inspired by the use of IBFD in digital subscriber lines, Ethernet, cable communication, and recently in wireless communication, we investigate the constraints and requirements for a successful IBFD implementation in BB-PLC. We propose a two-stage IBFD structure consisting of an initial analog isolation using an active hybrid circuit, and a simplified mixed-domain digital echo cancellation procedure to suppress the self-interference. Furthermore, we enhance the digital cancellation filter to better adapt to linear periodically time-varying channel conditions, commonly encountered in PLC scenarios. We evaluate our solution under diverse power line channel and noise conditions to examine the overall data rate gains that can be achieved. Last, we extend IBFD to multiple-input multiple-output BB-PLC systems that enable faster and/or more robust data transmission.
The role of alkalinity generation in controlling the fluxes of CO 2 during exposure and inundation on tidal flats

Abstract. Dissolved inorganic carbon (DIC), gaseous CO2 and alkalinity fluxes from intertidal sediments were investigated during periods of exposure and inundation, using laboratory core incubations, previously published field data and reactive transport model simulations. In the incubations and previous field data, it was found that during periods of alkalinity production (attributed to the accumulation of reduced sulfur species within the sediment), the flux of DIC out of the sediment was greater during inundation than the gaseous CO2 flux during exposure by a factor of up to 1.8. This finding was supported by computational simulations which indicated that large amounts of sulfate reduction and reduced sulfur burial (FeS) induce an alkalinity flux from the sediment during high tide conditions. Model simulations also found that the amount of reactive Fe in the sediment was a major driver of net alkalinity production. Our finding that CO2 fluxes can be significantly lower than total metabolism during exposure has implications for how total metabolism is quantified on tidal flats.
The Insurance Is the Lemon: Failing to Index Contracts

We model the widespread failure of contracts to share risk using available indices. A borrower and lender can share risk by conditioning repayments on an index. The lender has private information about the ability of this index to measure the true state the borrower would like to hedge. The lender is risk averse, and thus requires a premium to insure the borrower. The borrower, however, might be paying something for nothing, if the index is a poor measure of the true state. We provide sufficient conditions for this effect to cause the borrower to choose a non-indexed contract instead.
Fasting Whole Blood Fatty Acid Profile and Risk of Type 2 Diabetes in Adults: A Nested Case Control Study

Objective to determine the association of fasting whole blood fatty acid concentrations with incidence of type 2 diabetes in adults. Methods A nested case-control study of 187 subjects from a cohort of men and women aged 55–85 years from the Hunter Region, New South Wales, Australia. Fasting whole blood fatty acids were measured using gas chromatography and incidence of type 2 diabetes was ascertained by self-reported questionnaire at the study follow-up. Results After adjustment for potential confounding variables, positive associations with type 2 diabetes were seen for dihomo-gamma-linolenic acid (DGLA) (OR = 1.04, 95% CI:1.01–1.07, P = 0.01); arachidonic acid (ARA) (OR = 1.01, 95% CI:1.00–1.01, P = 0.002); alpha-linolenic acid (ALA) (OR = 1.10, 95% CI: 1.03–1.18, P = 0.01); eicosapentaenoic acid (EPA) (OR = 1.05, 95% CI:1.02–1.08, P = 0.001); and docosahexaenoic acid (DHA) (OR = 1.03, 95% CI:1.02–1.05, P<0.0001). Lignoceric acid is significantly associated with lower type 2 diabetes risk (OR = 0.95, 95% CI: 0.92–0.99, P = 0.01). Conclusion These data suggest that higher fasting whole blood concentrations of omega-6 polyunsaturated fatty acids (n-6PUFA) (ARA and DGLA) as well as omega-3 polyunsaturated fatty acid (n-3PUFA) (ALA, EPA, and DHA) are associated with an increased risk of diabetes, whereas increased fasting whole blood concentrations of lignoceric acid is inversely associated with diabetes risk.
Lithium-ion Battery Remaining Useful Life Prediction with Long Short-term Memory Recurrent Neural Network

Lithium-ion batteries play critical roles in many electronic devices. It is necessary to develop a reliable and accurate remaining useful life (RUL) prediction approach to provide timely maintenance or replacement of battery systems. A novel RUL prediction approach based on Long Short-term Memory (LSTM) Recurrent Neural Network (RNN) is proposed in this paper. LSTM is able to capture long-term dependencies and model sequential data among the capacity degradation of lithium-ion batteries. The advantages of our proposed method include: 1) obtaining high prediction accuracy without accurate physics-based model or expertise and 2) decreasing the cumulation errors by multi-step ahead prediction each time, while traditional RUL method predicts one-step ahead once and then uses the current estimated value to predict next one, which causes cumulation errors increased. The Center for Advanced Life Cycle Engineering (CALCE) battery datasets are used to demonstrate the effectiveness of the proposed method. The results show that, compared with echo state networks (ESN), the proposed method has higher accuracy, more stable and reliable performance for lithium-ion batteries RUL prediction.