Miracle-dz/UniFAR-FTUs huggingface dataset:
Factor V Leiden related Budd-Chiari syndrome

BACKGROUND The role of factor V Leiden as a cause of Budd-Chiari syndrome has only recently been described. AIMS To assess the specific features of factor V Leiden related Budd-Chiari syndrome. PATIENTS Sixty three consecutive patients with hepatic vein or terminal inferior vena cava thrombosis. METHODS Standardised chart review. RESULTS Factor V Leiden was found in 20 patients (31% (95% CI 20–43)). In the subgroup of patients with, compared with the subgroup without, factor V Leiden, a combination of prothrombotic states was more common (70% (95% CI 50–90) v 14% (95% CI 3–24)); inferior vena cava thrombosis was more frequent (40% (95% CI 19–61)v 7% (95% CI 0–14)); and distribution of initial alanine aminotransferase values was bimodal (almost normal or extremely increased) versus unimodal (p=0.003). Factor V Leiden accounted for four of five cases of massive ischaemic necrosis (transaminases >50-fold the upper limit of normal values) (p=0.014), and also for all three cases developing during pregnancy. Patients with and without factor V Leiden did not differ with regard to mortality, portosytemic shunting, or listing for liver transplantation. Hepatocellular carcinoma developed in two patients; both had factor V Leiden and indolent obstruction of the inferior vena cava. CONCLUSIONS In patients with Budd-Chiari syndrome, factor V Leiden (a) is common; (b) precipitates thrombosis mostly when combined with another risk factor; (c) is associated with one of two contrasting clinical pictures: indolent thrombosis—particularly of the inferior vena cava—or massive ischaemic necrosis; and (d) is a major cofactor of Budd-Chiari syndrome developing during pregnancy.
Valoração da família e condutas desviantes: testagem de um modelo teórico

Valuation of the family and deviant conducts: testing of a theoretical model. This study aimed to evaluate the internal consistency and structural validity of the indicators of internal valuation of the family its influence on deviant behavior in young. For that, there was an exploratory analysis of the main components, confirmatory analysis and structural equation modeling. A sample of 488 young people to exploratory analysis and another one of 345 young people to confirmatory analysis made this study and structural model. All the young people were from the primary and middle level of private and public schools in Joao Pessoa – PB and Palmas – TO and age between 14 and 18 years and males and females. They answered a questioner assessing the importance that the young people gave the seven attributes for their good family relationship. In exploratory analysis, the model unifactorial had a satisfactory result; these, confirmed, from indicators of adjust quality, in confirmatory analysis, as a model structurally acceptable. As well, the prediction of deviant behavior from the valuation of the family was established.
How Suboptimal is Training rPPG Models with Videos and Targets from Different Body Sites?

Remote camera measurement of the blood volume pulse via photoplethysmography (rPPG) is a compelling technology for scalable, low-cost, and accessible assessment of cardiovascular information. Neural networks currently provide the state-of-the-art for this task and supervised training or fine-tuning is an important step in creating these models. However, most current models are trained on facial videos using contact PPG measurements from the fingertip as targets/ labels. One of the reasons for this is that few public datasets to date have incorporated contact PPG measurements from the face. Yet there is copious evidence that the PPG signals at different sites on the body have very different morphological features. Is training a facial video rPPG model using contact measurements from another site on the body suboptimal? Using a recently released unique dataset with synchronized contact PPG and video measurements from both the hand and face, we can provide precise and quantitative answers to this question. We obtain up to 40 % lower mean squared errors between the waveforms of the predicted and the ground truth PPG signals using state-of-the-art neural models when using PPG signals from the forehead compared to using PPG signals from the fingertip. We also show qualitatively that the neural models learn to predict the morphology of the ground truth PPG signal better when trained on the forehead PPG signals. However, while models trained from the forehead PPG produce a more faithful waveform, models trained from a finger PPG do still learn the dominant frequency (i.e., the heart rate) well.
Random-Walk Drift-Diffusion Charge-Collection Model For Reverse-Biased Junctions Embedded in Circuits

A new computational model for charge transport based on parallelized random-walk drift-diffusion is proposed. This approach models the radiation-induced charge carriers as charge packets in a 3-D structure and the transport modeling are based on simple physical equations without any fitting parameter. This model has been dynamically coupled with a SPICE circuit simulator to take into account temporal variations of the electric fields in the charge collection process. Thus, the circuit electrical response modulates the charge collection efficiency. Three simulation cases have been explored and compared with TCAD simulations or radiation experiments in 65 nm technology to validate the accuracy of the proposed approach. These simulations demonstrate the capability of the proposed model to accurately estimate the soft error rate of complex structures, such as flip-flops over a large range of ionizing particle linear energy transfer. The proposed simulation methodology is also able to take into account charge-sharing phenomenon, and this point is highlighted by a specific investigation on the considered flip-flop.
Utilization of monoclonal antibodies for antigenic characterization of coronaviruses.

Hybrid cells secreting monoclonal antibodies against Bovine Enteric Coronavirus (BECV strain G110) were obtained by fusion between SP2/O myeloma cells and splenocytes of mice hyperimmunized with purified virus. Specificity of 8 from the 12 monoclonal antibodies was established to be anti-GP105 by immunochemical staining of viral polypeptides and by immunoprecipitation of radioactive-labelled viral proteins. The reactivity of three BECV isolates (strain G110, F15 and NCDCV) with the different monoclonal antibodies was studied by indirect immunofluorescence (IIF), ELISA, hemagglutination-inhibition and seroneutralization. G110 and F15 interacted in a similar manner with the monoclonal antibodies, but NCDCV failed to react with A9 monoclonal antibody. IIF test allowed us to detect another difference between U.K. BECV isolate and other BECV, in that the U.K. isolate did not react with F7 monoclonal antibody. No differences could be seen by IIF in the reactivity of Danish BECV isolate, Human Enteric Coronavirus (HECV), Bovine Respiratory Coronavirus (BRCV) and our BECV strains, with the 12 monoclonal antibodies. Human Respiratory Coronavirus (OC43), Porcine Hemagglutinating Encephalitis Virus (HEV) and BECV share common antigenic determinants which are outlined by the 6 non-neutralizing monoclonal antibodies. On the basis of the reactivity of coronaviruses with anti-BECV monoclonal antibodies, a distinction can be easily made between BECV and other coronaviruses, and differences were also detected within the BECV isolates. Interestingly HECV were found to be more closely related to BECV than to human OC43. These results show that monoclonal antibodies are of valuable help for biochemical and antigenic studies as well as for diagnostic procedures.
Sound 3-Query PCPPs Are Long

We initiate the study of the trade-off between the length of a probabilistically checkable proof of proximity (PCPP) and the maximal soundness that can be guaranteed by a 3-query verifier with oracle access to the proof. Our main observation is that a verifier limited to querying a short proof cannot obtain the same soundness as that obtained by a verifier querying a long proof. Moreover, we quantify the soundness deficiency as a function of the proof-length and show that any verifier obtaining “best possible” soundness must query an exponentially long proof. In terms of techniques, we focus on the special class of inspective verifiers that read at most 2 proof-bits per invocation. For such verifiers, we prove exponential length-soundness trade-offs that are later on used to imply our main results for the case of general (i.e., not necessarily inspective) verifiers. To prove the exponential trade-off for inspective verifiers, we show a connection between PCPP proof length and property-testing query complexity that may be of independent interest. The connection is that any linear property that can be verified with proofs of length ℓ by linear inspective verifiers must be testable with query complexity ≈ logℓ.
Web-based information content and its application to concept-based video retrieval

Semantic similarity between words or phrases is frequently used to find matching correlations between search queries and documents when straightforward matching of terms fails. This is particularly important for searching in visual databases, where pictures or video clips have been automatically tagged with a small set of semantic concepts based on analysis and classification of the visual content. Here, the textual description of documents is very limited, and semantic similarity based on WordNet's cognitive synonym structure, along with information content derived from term frequencies, can help to bridge the gap between an arbitrary textual query and a limited vocabulary of visual concepts. This approach, termed concept-based retrieval, has received significant attention over the last few years, and its success is highly dependent on the quality of the similarity measure used to map textual query terms to visual concepts. In this paper, we consider some issues of semantic similarity measures based on Information Content (IC), and propose a way to improve them. In particular, we note that most IC-based similarity measures are derived from a small and relatively outdated corpus (the Brown corpus), which does not adequately capture the usage pattern of many contemporary terms: for example, out of more than 150,000 WordNet terms, only about 36,000 are represented. This shortcoming reflects very negatively on the coverage of typical search query terms. We therefore suggest using alternative IC corpora that are larger and better aligned with the usage of modern vocabulary. We experimentally derive two such corpora using the WWW Google search engine, and show that they provide better coverage of vocabulary, while showing comparable frequencies for Brown corpus terms. Finally, we evaluate the two proposed IC corpora in the context of a concept-based video retrieval application using the TRECVID 2005, 2006, and 2007 datasets, and we show that they increase average precision results by up to 200%.
Incidence, risk factors, outcome and projected future burden of acute aortic dissection.

Acute aortic dissection has a high mortality rate, despite well-established treatment guidelines (1). Data on risk factors, incidence and outcome of aortic dissection are limited, largely due to a lack of contemporary population-based studies of this condition. Existing hospital-based studies, often from specialist centers or studies of retrospective registry data such as the International Registry of Acute Aortic Dissection (IRAD), may underestimate incidence and case fatality by incomplete inclusion of deaths prior to hospital admission, which might also bias assessment of risk factors and predictors of outcome. This research highlight outlines the findings of our recent population-based research of acute aortic dissection, which is the first-ever prospective epidemiological study of this condition (2). We studied event rates, incidence, risk factors, early case fatality, and long-term outcome of all acute aortic events occurring in a population of 92,728 in Oxfordshire, UK, during 2002-2012, as part of the Oxford Vascular Study (OXVASC). Using current incidence data and Office of National Statistics (ONS) population projections (3), we went on to predict UK incidence event rates for acute aortic dissection over the next 40 years.
FROM HUNKY HEROES TO DANGEROUS DINOSAURS

Using the UK Fire Brigades Union dispute of 2002–3 as a case study, this paper assesses current union–journalism relations and briefly outlines the FBU's campaign to access the news agenda. Using quantitative methodology, it analyses the dispute coverage in the UK national press. While there are some opportunities that unions can exploit, such as 24-hour news and live broadcasts, newspaper analysis indicates that national press coverage generally favoured government and other elite sources as primary definers. While the FBU was given at least equal space to put its case in nearly half of all articles, certain sections of the press seemed impervious to any amount of public relations activity: five out of the nine papers analysed—the Mail, Express, Telegraph, The Times and the Sun—reveal coverage heavily loaded against the union, with the Times and Sun giving negligible space to the union viewpoint and choosing to use overwhelmingly hostile sources, narratives and opinions. It concludes that, in line with the findings of previous studies by the Glasgow University Media Group, public relations and media strategies have limited impact, at least in the UK press.
An Algorithmic Proof of Suslin′s Stability Theorem for Polynomial Rings

Abstract Let k be a field. Then Gaussian elimination over k and the Euclidean division algorithm for the univariate polynomial ring k[x] allow us to write any matrix in SLn(k) or SLn(k[x]), n ≥ 2, as a product of elementary matrices. Suslin′s stability theorem states that the same is true for SLn(k[xl,., xm]) with n ≥ 3 and m ≥ 1. In this paper, we present an algorithmic proof of Suslin′s stability theorem, thus providing a method for finding an explicit factorization of a given polynomial matrix into elementary matrices. Grobner basis techniques may be used in the implementation of the algorithm.
An Emotionally Inexpressive (Type C) Coping Style Influences HIV Disease Progression at Six and Twelve Month Follow-ups

This study examined the effects of specific psychosocial factors on the progression of HIV infection in 200 HIV-1 seropositive but asymptomatic men and women. At baseline, participants' disease status was determined, and they were administered self-report assessments of coping style, social support and loneliness. Participants were classified at 6 and 12 month follow-ups as progressed or unchanged, compared to their baseline status. In logistic regression analyses, higher baseline Type C coping scores (indicating emotional inexpressiveness and decreased recognition of needs and feelings) significantly predicted progression at 6 months ( p <0.01) and 12 months ( p <0.02), but only among participants classified at baseline as CDC-A2 (between 200-499 CD4 cells/mm 3 ). In participants originally classified as CDC-A1 (CD4 cell counts > 500/mm 3 ), no psychosocial variable showed any significant relationship. Results emphasize the need to consider the disease context, as well as the interaction between biological and psychological factors in contributing to disease progression.
Revisiting Hash Table Design for Phase Change Memory

Phase Change Memory (PCM) is emerging as an attractive alternative to Dynamic Random Access Memory (DRAM) in building data-intensive computing systems. PCM offers read/write performance asymmetry that makes it necessary to revisit the design of in-memory applications. In this paper, we focus on in-memory hash tables, a family of data structures with wide applicability. We evaluate several popular hash-table designs to understand their performance under PCM. We find that for write-heavy workloads the designs that achieve best performance for PCMdiffer from the ones that are best for DRAM, and that designs achieving a high load factor also cause a high number of memory writes. Finally, we propose PFHT, a PCM-Friendly Hash Table which presents a cuckoo hashing variant that is tailored to PCM characteristics, and offers a better trade-off between performance, the amount of writes generated, and the expected load factor than any of the existing DRAMbased implementations.
Peak Capture Power Reduction for Compact Test Sets Using Opt-Justification-Fill

Excessive test power consumption is one of the obstacles which the chip industry currently faces. Peak capture power reduction typically leads to high pattern counts which increase test costs. This paper proposes a new methodology to reduce peak capture power during at-speed scan testing. In this method, a novel X-filling technique Opt-Justification-fill which uses optimization techniques to compute promising Xbits for low-power filling is proposed. This method is tightly integrated into a dynamic compaction flow to create silent test cubes with high compaction ability. By this, X-filling for fault detection and reducing switching activity is balanced. The proposed methodology can be applied during initial compact test set generation as well as a post-ATPG stage for a previously generated test set to reduce switching activity. Experiments show a significant reduction of peak capture power. At the same time, the pattern count increases only moderately which leads to reduced test costs.
Experiences of Depression: Theoretical, Clinical, and Research Perspectives

Recognizing these fundamentally different depressive experiences has spurred a remarkably wide range of research, the development of assessment tools, and impressive strides in understanding the nature, etiology, and treatment of this far-reaching disorder. With clarity he traces the extensive systematic investigation of these two types of depression and the role of disturbances in mental representations. A closing chapter considers the implications of these theoretical formulations and research findings for understanding the nature of therapeutic process with depressed patients.
Mouse embryo development following IVF in media containing either L-glutamine or glycyl-L-glutamine.

BACKGROUND The development of the mouse zygote following fertilization in vitro in a KSOM-type medium containing either L-glutamine or glycyl-L-glutamine has been examined, and compared with the development of mouse zygotes produced by natural fertilization. METHODS Mouse IVF, embryo culture and embryo transfer. RESULTS Fertilization rates, development to the blastocyst stage, implantation rate, gross fetal development and fetal body weight are not different in a KSOM-type medium containing either L-glutamine or glycyl-L-glutamine. No evidence of abnormal fetal development, such as exencephaly, was observed. The replacement of L-glutamine with glycyl-L-glutamine favoured the development of relatively more inner cell mass cells than trophectoderm cells, and reduced the numbers of pyknotic and fragmented nuclei in the blastocysts that developed in vitro. CONCLUSIONS There is no evidence that the presence of glutamine in the medium used for IVF influences significantly the subsequent development of the zygote. Replacing glutamine with glycyl-L-glutamine may be advantageous.
The Transformational Leader: The Key to Global Competitiveness

The Themes, The Protagonists, The Transformational Drama. RECOGNIZING THE NEED FOR REVITALIZATION. The Gathering Storm. Overcoming the Resistance to Change. CREATING A NEW VISION. Diagnosing the Problem. Creating a Motivating Vision. Mobilizing Commitment: Getting People Signed on to the Mission. INSTITUTIONALIZING CHANGE. Creative Destruction: Reweaving the Social Fabric. The Leader as Social Architect I: Making Bureaucracy Behave. The Leader as Social Architect II: Motivating People. EPILOGUE. History Repeats Itself. Notes. References. Index.
Icterus Neonatorum: Its Incidence and Cause

In spite of the frequency of icterus neonatorum and the work done to elucidate the problems connected with it, there still remains much divergence of opinion regarding its incidence and pathogenesis. Estimates of the incidence vary from 40 to 80 per cent. of the nYewborn. Since the detection of jaundice is influenced by many factors, such as the vascularity of the skin and the nature of the light in which the observation is made, and since there are several definitions of jaundice, such varying estimates are not surprising. Icterus neonatorum has been ascribed to excessive haemolysis of the blood, to immaturity of the liver, to increased viscosity of the bile, and to the breakdown of the mother's blood in the placenta. The hypothesis that the jaundice was hepatic in origin has been replaced by one that it is caused by excessive haemolysis. Since bilirubin is a product of the breakdown of haemoglobin, all jaundice may be said to be the result of haemolysis, but the evidence of excessive haemolysis as a cause of icterus neonatorum is inconclusive. During the past year, in the course of biochemical and haematological investigations of haemolysis, there occurred an opportunity to study newborn babies, and an investigation of icterus neonatorum was undertaken, (1) to determine the incidence, (2) to try to detect any difference in the rate of haemolysis in jaundiced and non-jaundiced infants, and (3) to seek evidence of impairment or immaturity of liver function.
How can systematic reviews incorporate qualitative research? A critical perspective

Systematic review has developed as a specific methodology for searching for, appraising and synthesizing findings of primary studies, and has rapidly become a cornerstone of the evidence-based practice and policy movement. Qualitative research has traditionally been excluded from systematic reviews, and much effort is now being invested in resolving the daunting methodological and epistemological challenges associated with trying to move towards more inclusive forms of review. We describe our experiences, as a very diverse multidisciplinary group, in attempting to incorporate qualitative research in a systematic review of support for breastfeeding. We show how every stage of the review process, from asking the review question through to searching for and sampling the evidence, appraising the evidence and producing a synthesis, provoked profound questions about whether a review that includes qualitative research can remain consistent with the frame offered by current systematic review methodology. We conclude that more debate and dialogue between the different communities that wish to develop review methodology is needed, and that attempts to impose dominant views about the appropriate means of conducting reviews of qualitative research should be resisted so that innovation can be fostered.
High-Performance SOI-MEMS Gyroscope with Decoupled Oscillation Modes

This paper presents a new, high-performance SOI-MEMS gyroscope with decoupled oscillation modes. The gyroscope structure allows to achieve matched-resonance-frequencies, large drive-mode oscillation amplitude, high sense-mode quality factor, and low mechanical crosstalk, demonstrating a measured noise-equivalent rate of 90 (deg/hr)/Hz1/2even at atmospheric pressure. The angular rate sensitivity of the gyroscope is 100 µ V/(deg/sec) at atmospheric pressure. This value improves to 2.4mV/(deg/sec) at vacuum, for which the measured noise-equivalent rate of the gyroscope reaches to 35 (deg/hr)/Hz1/2. The R2-nonlinearity of the gyroscope is measured to be better than 0.02%. The gyroscope has a low quadrature signal of 70deg/sec and a short-term bias stability of 1.5deg/sec.
Calcium and Other Ions in Blood and Skeleton of Nicaraguan Fresh-Water Shark

The bull shark, Carcharhinus leucas, employing archaic but effective means of regulating the physical-chemical composition of its body fluids, thrives in tropical fresh-water rivers and lakes. The ionic strength of the serum and the concentrations of total solutes, calcium, urea, and other ions are below the levels found in marine elasmobranchs but higher than the levels in teleosts. The patterns of the calcium deposits of the vertebrae are identical in marine and fresh-water subspecies.