Miracle-dz/UniFAR-FTUs huggingface dataset:
Transformerless Single-Phase Multilevel-Based Photovoltaic Inverter

The elimination of the output transformer from grid- connected photovoltaic (PV) systems not only reduces the cost, size, and weight of the conversion stage but also increases the system overall efficiency. However, if the transformer is removed, the galvanic isolation between the PV generator and the grid is lost. This may cause safety hazards in the event of ground faults. In addition, the circulation of leakage currents (common-mode currents) through the stray capacitance between the PV array and the ground would be enabled. Furthermore, when no transformer is used, the inverter could inject direct current (dc) to the grid, causing the saturation of the transformers along the distribution network. While safety requirements in transformerless systems can be met by means of external elements, leakage currents and the injection of dc into the grid must be guaranteed topologically or by the inverter's control system. This paper proposes a new high-efficiency topology for transformerless systems, which does not generate common-mode currents and topologically guarantees that no dc is injected into the grid. The proposed topology has been verified in a 5-kW prototype with satisfactory results.
Improving numeracy through values affirmation enhances decision and STEM outcomes

Greater numeracy has been correlated with better health and financial outcomes in past studies, but causal effects in adults are unknown. In a 9-week longitudinal study, undergraduate students, all taking a psychology statistics course, were randomly assigned to a control condition or a values-affirmation manipulation intended to improve numeracy. By the final week in the course, the numeracy intervention (statistics-course enrollment combined with values affirmation) enhanced objective numeracy, subjective numeracy, and two decision-related outcomes (financial literacy and health-related behaviors). It also showed positive indirect-only effects on financial outcomes and a series of STEM-related outcomes (course grades, intentions to take more math-intensive courses, later math-intensive courses taken based on academic transcripts). All decision and STEM-related outcome effects were mediated by the changes in objective and/or subjective numeracy and demonstrated similar and robust enhancements. Improvements to abstract numeric reasoning can improve everyday outcomes.
Exact MIMO Zero-Forcing Detection Analysis for Transmit-Correlated Rician Fading

We analyze the performance of multiple input/multiple output (MIMO) communications systems employing spatial multiplexing and zero-forcing detection (ZF). The distribution of the ZF signal-to-noise ratio (SNR) is characterized when either the intended stream or interfering streams experience Rician fading, and when the fading may be correlated on the transmit side. Previously, exact ZF analysis based on a well-known SNR expression has been hindered by the noncentrality of the Wishart distribution involved. In addition, approximation with a central-Wishart distribution has not proved consistently accurate. In contrast, the following exact ZF study proceeds from a lesser-known SNR expression that separates the intended and interfering channel-gain vectors. By first conditioning on, and then averaging over the interference, the ZF SNR distribution for Rician-Rayleigh fading is shown to be an infinite linear combination of gamma distributions. On the other hand, for Rayleigh-Rician fading, the ZF SNR is shown to be gamma-distributed. Based on the SNR distribution, we derive new series expressions for the ZF average error probability, outage probability, and ergodic capacity. Numerical results confirm the accuracy of our new expressions, and reveal effects of interference and channel statistics on performance.
3.3 A 14nm 1GHz FPGA with 2.5D transceiver integration

A Field Programmable Gate Array (FPGA) family was designed to match a programmable fabric die built in 14nm process technology with 28Gb/s transceiver dice. The 2.5D packaging (Fig. 3.3.1) uses embedded interconnect bridges (EMIB) [1]. 20nm transceivers were reused enabling a transceiver roadmap independent of FPGA fabric. Fig. 3.3. 2 shows a 560mm2 fabric die and six transceiver dice. The programmable fabric contains 2.8M logic elements, DSP, memory components, and routing interconnect operating at up to 1GHz. Applications drove the need for improved flexibility and security of the FPGA configuration system. A triple-modular redundant microprocessor-based secure device manager (SDM) was designed and is programmed by embedded software.
Regulation of Tissue LC-PUFA Contents, Δ6 Fatty Acyl Desaturase (FADS2) Gene Expression and the Methylation of the Putative FADS2 Gene Promoter by Different Dietary Fatty Acid Profiles in Japanese Seabass (Lateolabrax japonicus)

The present study was conducted to evaluate the influences of different dietary fatty acid profiles on the tissue content and biosynthesis of LC-PUFA in a euryhaline species Japanese seabass reared in seawater. Six diets were prepared, each with a characteristic fatty acid: Diet PA: Palmitic acid (C16:0); Diet SA: Stearic acid (C18:0); Diet OA: Oleic acid (C18:1n-9); Diet LNA: α-linolenic acid (C18:3n-3); Diet N-3 LC-PUFA: n-3 LC-PUFA (DHA+EPA); Diet FO: the fish oil control. A 10-week feeding trial was conducted using juvenile fish (29.53±0.86 g). The results showed that Japanese seabass had limited capacity to synthesize LC-PUFA and fish fed PA, SA, OA and LNA showed significantly lower tissue n-3 LC-PUFA contents compared to fish fed N-3 LC-PUFA and FO. The putative gene promoter and full-length cDNA of FADS2 was cloned and characterized. The protein sequence was confirmed to be homologous to FADS2s of marine teleosts and possessed all the characteristic features of microsomal fatty acid desaturases. The FADS2 transcript levels in liver of fish fed N-3 LC-PUFA and FO were significantly lower than those in fish fed other diets except LNA while Diet PA significantly up-regulated the FADS2 gene expression compared to Diet LNA, N-3 LC-PUFA and FO. Inversely, fish fed N-3 LC-PUFA and FO showed significantly higher promoter methylation rates of FADS2 gene compared to fish fed the LC-PUFA deficient diets. These results suggested that Japanese seabass had low LC-PUFA synthesis capacity and LC-PUFA deficient diets caused significantly reduced tissue n-3 LC-PUFA contents. The liver gene expression of FADS2 was up-regulated in groups enriched in C16:0, C18:0 and C18:1n-9 respectively but not in the group enriched in C18:3n-3 compared to groups with high n-3 LC-PUFA contents. The FADS2 gene expression regulated by dietary fatty acids was significantly negatively correlated with the methylation rate of putative FADS2 gene promoter.
Continuous positive airway pressure improves vascular function in obstructive sleep apnoea/hypopnoea syndrome: a randomised controlled trial

Background: The obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is associated with hypertension and increased cardiovascular risk, particularly when accompanied by marked nocturnal hypoxaemia. The mechanisms of these associations are unclear. We hypothesised that OSAHS combined with severe nocturnal hypoxaemia causes impaired vascular function that can be reversed by continuous positive airways pressure (CPAP) therapy. Methods: We compared vascular function in two groups of patients with OSAHS: 27 with more than 20 4% desaturations/h (desaturator group) and 19 with no 4% and less than five 3% desaturations/h (non-desaturator group). In a randomised, double blind, placebo controlled, crossover trial, the effect of 6 weeks of CPAP therapy on vascular function was determined in the desaturator group. In all studies, vascular function was assessed invasively by forearm venous occlusion plethysmography during intra-arterial infusion of endothelium dependent (acetylcholine 5–20 μg/min and substance P 2–8 pmol/min) and independent (sodium nitroprusside 2–8 μg/min) vasodilators. Results: Compared with the non-desaturator group, patients with OSAHS and desaturations had reduced vasodilatation to all agonists (p = 0.007 for all). The apnoea/hypopnoea index and desaturation frequency were inversely related to peak vasodilatation with acetylcholine (r = −0.44, p = 0.002 and r = −0.43, p = 0.003) and sodium nitroprusside (r = −0.42, p = 0.009 and r = −0.37, p = 0.02). In comparison with placebo, CPAP therapy improved forearm blood flow to all vasodilators (p = 0.01). Conclusions: Patients with OSAHS and frequent nocturnal desaturations have impaired endothelial dependent and endothelial independent vasodilatation that is proportional to hypoxaemia and is improved by CPAP therapy. Impaired vascular function establishes an underlying mechanism for the adverse cardiovascular consequences of OSAHS.
Mechanisms of Autoimmunity

The immune system is capable of recognizing any molecule that enters the body through a parenteral route. For that purpose, the lymphocyte population generates a large, diverse repertoire of receptors. Inevitably, many of these receptors recognize endogenous host antigens as well as exogenous molecules. Thus, self-reactive B cells and T cells are present in normal individuals and are potentially capable of producing an autoimmune response. The host consequently depends on certain mechanisms to avoid the harmful effects of autoimmunity. These mechanisms include negative selection in the thymus and bone marrow to delete the higher-affinity T and B cells and peripheral regulatory mechanisms, such as anergy, ignorance, and suppression. Despite such protective mechanisms, autoimmune diseases, collectively, are common in industrialized societies, even though individually most autoimmune diseases are rare. The diseases present differently depending on the site of pathology but share many fundamental mechanisms.
The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology

Mobile element insertions (MEIs) represent ∼25% of all structural variants in human genomes. Moreover, when they disrupt genes, MEIs can influence human traits and diseases. Therefore, MEIs should be fully discovered along with other forms of genetic variation in whole genome sequencing (WGS) projects involving population genetics, human diseases, and clinical genomics. Here, we describe the Mobile Element Locator Tool (MELT), which was developed as part of the 1000 Genomes Project to perform MEI discovery on a population scale. Using both Illumina WGS data and simulations, we demonstrate that MELT outperforms existing MEI discovery tools in terms of speed, scalability, specificity, and sensitivity, while also detecting a broader spectrum of MEI-associated features. Several run modes were developed to perform MEI discovery on local and cloud systems. In addition to using MELT to discover MEIs in modern humans as part of the 1000 Genomes Project, we also used it to discover MEIs in chimpanzees and ancient (Neanderthal and Denisovan) hominids. We detected diverse patterns of MEI stratification across these populations that likely were caused by (1) diverse rates of MEI production from source elements, (2) diverse patterns of MEI inheritance, and (3) the introgression of ancient MEIs into modern human genomes. Overall, our study provides the most comprehensive map of MEIs to date spanning chimpanzees, ancient hominids, and modern humans and reveals new aspects of MEI biology in these lineages. We also demonstrate that MELT is a robust platform for MEI discovery and analysis in a variety of experimental settings.
An Open-Label, Split-Face Trial Evaluating Efficacy and Safty of Photopneumatic Therapy for the Treatment of Acne

Background Acne vulgaris is the most common skin disease worldwide, with many available treatment modalities, including oral and topical medications and laser therapy. Recently, a novel device (Isolaz, Pleasanton, CA, USA) that combines vacuum pressure and a broadband light source (400 nm to 1,200 nm) was developed for the treatment of acne. Objective To determine the clinical efficacy and safety of photopneumatic therapy for the treatment of acne vulgaris of the face. Methods Twenty adults with mild to moderate facial acne vulgaris received 4 successive treatments on one side of the face with a combined photopneumatic device (intense pulsed light: fluence=5.8 J/cm2; negative pressure=iMP mode) at 2 week intervals. Acne lesions on the opposite side of the face were not treated. Lesion counts were performed at baseline, prior to each treatment session, and at 3 months after the final treatment session. Results Significant lesion improvements and reduced numbers of acne lesions were observed on the treated side of the faces. Most patients experienced global clinical improvement. No severe side effects occurred during the study, with only a few patients experiencing transient erythema, purpura and/or exacerbation of pre-existing acne. Conclusion Photopneumatic therapy is a safe and effective treatment for mild to moderate acne vulgaris.
The Genetic Code via Gödel Encoding

The genetic code structure into distinct multiplet-classes as well as the numeric degeneracies of the latter are revealed by a two-step process. First, an empirical inventory of the degeneracies (of the shuffled multiplets) in two speci- fic equal moieties of the experimental genetic code table is made and transcribed in the form of a sequence of integers. Second, a Godel Encoding procedure is applied to the latter sequence delivering, as an output, a Godel Number the digits of which, from the decimal representation, could remarkably describe the amino acids and the stops and allow us also to compute the exact degeneracies, class by class. The standard and the vertebrate mitochondrial genetic codes are conside- red and their multiplet structure is fully established.
Three Dimensional Morphology of β-Al5FeSi Intermetallics in AlSi Alloys

Iron is the most common and detrimental impurity in casting alloys and has been associated with many defects. The main consequence of the presence or adding of iron to AlSi alloys is the formation Fe-rich intermetallics with especially deleterious β-Al5FeSi. β-Al5FeSi phases are most often called needles on 2D micro sections, whilst platelets in 3D geometry. The x-ray tomography results have demonstrated Ferich phases with shapes different from simple forms such as needles or platelets and presented bent and branched phases. β grown as complicated structure of bent and branched intermetallics can decrease feeding ability, strengthen pores nucleation and eutectic colonies nucleation leading to lower permeability of mushy zone and porosity in the castings.
Process of Nanocrystallization and Partial Amorphization by Cold Rolling in TiNi

TiNi alloy is vulnerable to solid-state crystalline-amorphous transformation by many means, such as particle irradiation, shot peening, compression and cold rolling. In the present study a process of structural refinement and partial amorphization by cold rolling was studied on Ti-50.2 at%Ni. Crystal structures and microstructures were characterized by X-ray diffractometry, optical microscopy and electron microscopy. Differential scanning calorimetry revealed that the introduction of high density of dislocations and resultant structural refinement by cold rolling suppressed martensitic transformation. In the transversal section of cold rolled samples, microscopic and macroscopic shear band formation was observed after 40-50% rolling. Transmission electron microscopy observations revealed that amorphous bands exist in the sample with rolling reduction over 40%. The amorphous bands form about 35-45 degrees with respect to the rolling direction. This suggests that a part of the shear bands becomes amorphous.
Generation of Transduction-Competent Retroviral Vectors by Infection with a Single Hybrid Vaccinia Virus

ABSTRACT Recombinant vaccinia viruses that express defective retroviral vectors upon a single infection event in normal host cells were constructed. The gag-pol and envelope genes and a retroviral vector unit were inserted as vaccinia virus promoter-controlled transcription units at three separate loci. The triple recombinant virus was used to infect such diverse cell types as monkey and rabbit kidney, human lung, and primary chicken cells, resulting in the production of transduction-competent defective retroviral vectors. Infection of Chinese hamster ovary cells, which are nonpermissive for vaccinia virus replication, also resulted in production of retroviral vectors and secondary permanent transduction of the host cells. Since vaccinia virus supports the expression of cytotoxic proteins, the vesicular stomatitis virus G glycoprotein could be chosen as the envelope allowing a broad host range of transduction. Functionality of particles was monitored by expression of the green fluorescent protein in transduced 3T3 cell clones. This is the first description of a single chimeric virus encoding and releasing functional retroviral vectors, providing proof of principle of the new concept. No replication-competent retrovirus was detectable by sensitive reverse transcriptase assays. Since vaccinia virus has a broad host range, is extremely robust, and can be obtained at high titers and safe nonreplicating vaccinia virus strains are available, the hybrid system may open new perspectives for gene delivery.
Internet addiction among Chinese adolescents: prevalence and psychological features.

BACKGROUND To investigate the prevalence of Internet addiction among Chinese adolescents and to explore the psychological features associated with Internet addiction. METHODS A total of 2620 high school students from four high schools in Changsha City were surveyed using Diagnostic Questionnaire for Internet Addiction (YDQ), Eysenck Personality Questionnaire (the edition for children, EPQ), Time Management Disposition Scale (TMDS) and Strengths and Difficulties Questionnaire (SDQ). The mean age of whole sample was 15.19 years (ranging from 12 years to 18 years). According to the modified YDQ criteria by Beard, 64 students who were diagnosed as Internet addiction (the mean age: 14.59 years) and 64 who were diagnosed as being normal in Internet usage (the mean age: 14.81 years) were included in a case-control study. RESULTS The rate of Internet use among the surveyed adolescents was 88%, among which the incidence rate of Internet addiction was 2.4%. The Internet addiction group had significantly higher scores on the EPQ subscales of neuroticism, psychoticism, and lie than the control group (P < 0.05). The Internet addiction group scored lower than the control group on the TMDS subscales of sense of control over time, sense of value of time, and sense of time efficacy (P < 0.05). Compared with the control group, the Internet addiction group had also significantly higher scores on the SDQ subscales of emotional symptoms, conduct problems, hyperactivity, total difficulties and lower scores on the subscale of prosocial behaviours (P < 0.05). CONCLUSIONS The present study suggests that Internet addiction is not rare among Chinese adolescents. In addition, adolescents with Internet addiction possess different psychological features when compared with those who use the Internet less frequently.
Feedbacks for non-autonomous regular linear systems

We introduce non-autonomous well-posed and (absolutely) regular linear systems as quadrupels consisting of an evolution family and output, input and input-output maps subject to natural hypotheses. In the spirit of G. Weiss' work these maps are represented in terms of admissible observation and control operators (the latter in an approximative sense) in the time domain. In this setting the closed-loop system exists for a canonical class of ‘admissible’ feedbacks, and it inherits the absolute regularity and other properties of the given system. In particular, one can iterate feedbacks.
Telangiectatic osteosarcoma: a review of literature

Telangiectatic osteosarcoma is a rare variant of osteosarcoma and hence its occurrence, presentation, and prognosis are poorly understood. With advancements in technology and available treatment options, the scenario of its diagnosis, management, and outcome has changed. Chemotherapy with surgery was challenged previously, but has now been proved to be beneficial. We reviewed the available literature and compared results to define the characteristics of the disease, its presentation, radiographic and pathologic features, optimal treatment, and prognosis.
Transcervical Submandibular Sialoadenectomy

The submandibular glands are subject to several pathologies that require excision. The most common problem that affects these salivary glands is sialadenitis combined with sialolithiasis. This problem occurs in the submandibular gland 10 times more frequently than it does in the parotid gland. Other illnesses frequently involving the submandibular glands are represented by sialadenosis and benign, malign, and intermediate neoplasms. Diagnosis of any disturbance in the submandibular gland involves both a clinical and instrumental (echography, traditional radiography [ortopantomography] and eventually computed tomography (CT) or magnetic resonance imaging) assessment. Surgery is the usual method of treatment of both chronic sialadenitis and neoplasms in the submandibular gland. A submandibular gland surgical approach can be cervical, intraoral, or endoscopic. The authors present their clinical experience with a total of 40 patients with illnesses involving the submandibular gland treated with submandibular gland excision by a transcervical approach. Their experience suggests that this approach entails a relatively simple procedure, involves low risks for the nerve structure around the gland, permits wide resection margins for neoplasms, and incurs little aesthetic damage.
Effects of blood and virus‐infected blood on protein expression in the midgut of the dengue vector Aedes albopictus

Abstract Although the mosquito midgut is the primary site of bloodmeal storage and the first line of defence against pathogenic infection, little is known about its proteic composition at a time when an increasing number of proteins are reported to impair viral infection. Aedes albopictus Skuse (Diptera: Culicidae) is an important vector of the dengue virus. We compared 2‐dimensional protein profiles of the adult midgut in this species, taking into account bloodmeal status. The comparison of profiles from sugar‐fed and blood‐fed females showed that a considerable number of proteins were present in both midguts. In addition, one set of proteins was present only after sugar intake and another set only after blood intake. The comparison of profiles of blood‐fed midguts and dengue virus‐2 infected blood‐fed midguts revealed that at least six proteins were present only in the infected midguts. These results are discussed in the context of the identification of midgut proteins involved in the dengue virus infection process.
Climatic Fluctuations and the Diffusion of Agriculture

Abstract This research examines the climatic origins of the diffusion of Neolithic agriculture across countries and archaeological sites. The theory suggests that a foraging society's history of climatic shocks shaped the timing of its adoption of farming. Specifically, as long as climatic disturbances did not lead to a collapse of the underlying resource base, the rate at which hunter-gatherers were climatically propelled to experiment with their habitats determined the accumulation of tacit knowledge complementary to farming. Consistent with the proposed hypothesis, the empirical investigation demonstrates that, conditional on biogeographic endowments, climatic volatility has a hump-shaped effect on the timing of the adoption of agriculture.