Miracle-dz/UniFAR-FTUs huggingface dataset:
Superconductivity in fullerides

Experimental studies of the superconductive properties of fullerides are briefly reviewed. Theoretical calculations of the electron-phonon coupling, in particular for the intramolecular phonons, are discussed extensively. The calculations are compared with coupling constants deduced from a number of different experimental techniques. It is discussed why A{sub 3}C{sub 60} are not Mott-Hubbard insulators, in spite of the large Coulomb interaction. Estimates of the Coulomb pseudopotential {mu}{sup {asterisk}}, describing the effect of the Coulomb repulsion on the superconductivity, as well as possible electronic mechanisms for the superconductivity, are reviewed. The calculation of various properties within the Migdal-Eliashberg theory and attempts to go beyond this theory are described. {copyright} {ital 1997} {ital The American Physical Society}
On Obstructing Obscenity Obfuscation

Obscenity (the use of rude words or offensive expressions) has spread from informal verbal conversations to digital media, becoming increasingly common on user-generated comments found in Web forums, newspaper user boards, social networks, blogs, and media-sharing sites. The basic obscenity-blocking mechanism is based on verbatim comparisons against a blacklist of banned vocabulary; however, creative users circumvent these filters by obfuscating obscenity with symbol substitutions or bogus segmentations that still visually preserve the original semantics, such as writing shit as $h¡;t or s.h. i.t or even worse mixing them as $. h…. ¡. t. The number of potential obfuscated variants is combinatorial, yielding the verbatim filter impractical. Here we describe a method intended to obstruct this anomaly inspired by sequence alignment algorithms used in genomics, coupled with a tailor-made edit penalty function. The method only requires to set up the vocabulary of plain obscenities; no further training is needed. Its complexity on screening a single obscenity is linear, both in runtime and memory, on the length of the user-generated text. We validated the method on three different experiments. The first one involves a new dataset that is also introduced in this article; it consists of a set of manually annotated real-life comments in Spanish, gathered from the news user boards of an online newspaper, containing this type of obfuscation. The second one is a publicly available dataset of comments in Portuguese from a sports Web site. In these experiments, at the obscenity level, we observed recall rates greater than 90%, whereas precision rates varied between 75% and 95%, depending on their sequence length (shorter lengths yielded a higher number of false alarms). On the other hand, at the comment level, we report recall of 86%, precision of 91%, and specificity of 98%. The last experiment revealed that the method is more effective in matching this type of obfuscation compared to the classical Levenshtein edit distance. We conclude discussing the prospects of the method to help enforcing moderation rules of obscenity expressions or as a preprocessing mechanism for sequence cleaning and/or feature extraction in more sophisticated text categorization techniques.
Heart failure in different occupational classes in Sweden.

AIMS The link between low socioeconomic status (SES) and coronary heart disease (CHD) is well established, but there is a paucity of data whether a similar relation exists for heart failure (HF). METHODS AND RESULTS A total of 6999 men 47-55 years old, without a prior stroke or myocardial infarction, from a population sample of 9998 men, were investigated during 1970-73. Over a 28-year follow-up, 1004 men (14.3%) were discharged from hospital or died with a diagnosis of HF. There was an inverse relationship between SES, measured as an occupational class, and future risk of HF. Compared with men in the highest occupational class, men with intermediate non-manual occupations had a multiple-adjusted hazard ratio (HR) of 1.28, 95% confidence interval (CI) 0.98-1.67, lower officials and foremen had an HR of 1.57 (1.22-2.03), semiskilled and skilled workers 1.48 (1.15-1.89), and unskilled workers 1.72 (1.34-2.20). Results were similar if only men with a principal diagnosis of HF (n=516) were considered, irrespective of whether a diagnosis of acute myocardial infarction or coronary revascularization had been recorded at any time. CONCLUSION Low SES is an independent risk factor for long-term risk of HF in men.
A study into the impact of the Reading Education Assistance Dogs scheme on reading engagement and motivation to read among Early Years Foundation-Stage children

ABSTRACT This research explores the impact of the Reading Education Assistance Dogs (READ) scheme on reading engagement and motivation among Early Years Foundation-Stage children using a case study approach at a primary school in the English Midlands. There is a notable lack of UK-based research into the READ scheme, which offers a potential alternative method for promoting engagement among young readers. This study used qualitative techniques to determine if the READ scheme is reported to have an impact; and if so, what type of impact. The findings suggest that the READ scheme is successful in a number of areas, including promoting engagement, increased motivation, improved attainment, fostering children’s enjoyment and promoting a love of reading, alongside other additional benefits for specific target groups. It must be recognised that this case study is based on a small pool of opportunity-sampled participants, so the findings cannot be further generalised, but do provide a useful insight into an under-researched area, as a starting point for which more specific aspects and impacts could be investigated.
Decreased expression of the APOA1–APOC3–APOA4 gene cluster is associated with risk of Alzheimer’s disease

Background Apolipoprotein is genetically associated with the risk of Alzheimer’s disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. Therefore, this gene cluster may be related to the risk of AD. Patients and methods A total of 147 AD patients and 160 healthy controls were randomly recruited from June 2013 to August 2014. APOA1, APOC3, and APOA4 levels were measured using real-time quantitative reverse-transcriptase polymerase chain reaction and enzyme-linked immunosorbent assay. Results APOA1, APOC3 and APOA4 levels were significantly lower in AD patients than controls (P<0.01). APOA1, APOC3, and APOA4 levels were negatively related with the severities of AD determined by Clinical Dementia Rating scores (P<0.01). APOA1, APOC3, and APOA4 levels showed a negative relation with Montgomery–Åsberg Depression Rating Scale scores and a positive relation with RAND 36-item health-survey scores (P<0.01). There was a decreased trend for levels of APOA1, APOC3, and APOA4 in AD patients. Conclusion Low levels of APOA1, APOC3, and APOA4 are associated with risk of AD. APOA1, APOC3, and APOA4 should be developed as combined drugs for the therapy of AD.
The Action Mechanism of the Myc Inhibitor Termed Omomyc May Give Clues on How to Target Myc for Cancer Therapy

Recent evidence points to Myc – a multifaceted bHLHZip transcription factor deregulated in the majority of human cancers – as a priority target for therapy. How to target Myc is less clear, given its involvement in a variety of key functions in healthy cells. Here we report on the action mechanism of the Myc interfering molecule termed Omomyc, which demonstrated astounding therapeutic efficacy in transgenic mouse cancer models in vivo. Omomyc action is different from the one that can be obtained by gene knockout or RNA interference, approaches designed to block all functions of a gene product. This molecule – instead – appears to cause an edge-specific perturbation that destroys some protein interactions of the Myc node and keeps others intact, with the result of reshaping the Myc transcriptome. Omomyc selectively targets Myc protein interactions: it binds c- and N-Myc, Max and Miz-1, but does not bind Mad or select HLH proteins. Specifically, it prevents Myc binding to promoter E-boxes and transactivation of target genes while retaining Miz-1 dependent binding to promoters and transrepression. This is accompanied by broad epigenetic changes such as decreased acetylation and increased methylation at H3 lysine 9. In the presence of Omomyc, the Myc interactome is channeled to repression and its activity appears to switch from a pro-oncogenic to a tumor suppressive one. Given the extraordinary therapeutic impact of Omomyc in animal models, these data suggest that successfully targeting Myc for cancer therapy might require a similar twofold action, in order to prevent Myc/Max binding to E-boxes and, at the same time, keep repressing genes that would be repressed by Myc.
Civil Wars Kill and Maim People—Long After the Shooting Stops

Political scientists have conducted only limited systematic research on the consequences of war for civilian populations. Here we argue that the civilian suffering caused by civil war extends well beyond the period of active warfare. We examine these longer-term effects in a cross-national (1999) analysis of World Health Organization new fine-grained data on death and disability broken down by age, gender, and type of disease or condition. We test hypotheses about the impact of civil wars and find substantial long-term effects, even after controlling for several other factors. We estimate that the additional burden of death and disability incurred in 1999, from the indirect and lingering effects of civil wars in the years 1991–97, was approximately equal to that incurred directly and immediately from all wars in 1999. This impact works its way through specific diseases and conditions and disproportionately affects women and children.We thank the Weatherhead Initiative on Military Conflict as a Public Health Problem, the Ford Foundation, and the World Health Organization, NIA (P01 17625-01), for financial support and Gary King, Thomas Gariepy, Melvin Hinich, Kosuke Imai, Roy Licklider, Jennifer Leaning, Greg Huber, Lisa Martin, Christopher Murray, Joshua Salomon, and Nicholas Sambanis for comments. Our data are available at http://www.yale. edu/unsy/civilwars/data.htm and at the Virtual Data Center web site, http://TheData.org, when it becomes operative.
Susceptibility Imaging in Glial Tumor Grading; Using 3 Tesla Magnetic Resonance (MR) System and 32 Channel Head Coil

Summary Background Susceptibility weighted imaging (SWI) is a velocity compensated, high-resolution three-dimensional (3D) spoiled gradient-echo sequence that uses magnitude and filtered-phase data. SWI seems to be a valuable tool for non-invasive evaluation of central nervous system gliomas. Relative cerebral blood volume (rCBV) ratio is one of the best noninvasive methods for glioma grading. Degree of intratumoral susceptibility signal (ITSS) on SWI correlates with rCBV ratio and histopathological grade. This study investigated the effectiveness of ITSS grading and rCBV ratio in preoperative assessment. Material/Methods Thirty-one patients (17 males and 14 females) with histopathogical diagnosis of glial tumor undergoing routine cranial MRI, SWI, and perfusion MRI examinations between October 2011 and July 2013 were retrospectively enrolled. All examinations were performed using 3T apparatus with 32-channel head coil. We used ITSS number for SWI grading. Correlations between SWI grade, rCBV ratio, and pathological grading were evaluated. ROC analysis was performed to determine the optimal rCBV ratio to distinguish between high-grade and low-grade glial tumors. Results There was a strong positive correlation between both pathological and SWI grading. We determined the optimal rCBV ratio to discriminate between high-grade and low-grade tumors to be 2.21 Conslusions In conclusion, perfusion MRI and SWI using 3T MR and 32-channel head coil may provide useful information for preoperative glial tumor grading. SWI can be used as an accessory to perfusion MR technique in preoperative tumor grading.
Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca2+-ATPase (PfSERCA or PfATP6) has been speculated to be the target of ARTs and thus a potential marker for ART resistance. Here we amplified and sequenced pfatp6 gene (∼3.6 Kb) in 213 samples collected after 2005 from the Greater Mekong Subregion, where ART drugs have been used extensively in the past. A total of 24 single nucleotide polymorphisms (SNPs), including 8 newly found in this study and 13 nonsynonymous, were identified. However, these mutations were either uncommon or also present in other geographical regions with limited ART use. None of the mutations were suggestive of directional selection by ARTs. We further analyzed pfatp6 from a worldwide collection of 862 P. falciparum isolates in 19 populations from Asia, Africa, South America and Oceania, which include samples from regions prior to and after deployments ART drugs. A total of 71 SNPs were identified, resulting in 106 nucleotide haplotypes. Similarly, many of the mutations were continent-specific and present at frequencies below 5%. The most predominant and perhaps the ancestral haplotype occurred in 441 samples and was present in 16 populations from Asia, Africa, and Oceania. The 3D7 haplotype found in 54 samples was the second most common haplotype and present in nine populations from all four continents. Assessment of the selection strength on pfatp6 in the 19 parasite populations found that pfatp6 in most of these populations was under purifying selection with an average dN/dS ratio of 0.333. Molecular evolution analyses did not detect significant departures from neutrality in pfatp6 for most populations, challenging the suitability of this gene as a marker for monitoring ART resistance.
Cross-Domain Statistical–Sequential Dependencies Are Difficult to Learn

Recent studies have demonstrated participants’ ability to learn cross-modal associations during statistical learning tasks. However, these studies are all similar in that the cross-modal associations to be learned occur simultaneously, rather than sequentially. In addition, the majority of these studies focused on learning across sensory modalities but not across perceptual categories. To test both cross-modal and cross-categorical learning of sequential dependencies, we used an artificial grammar learning task consisting of a serial stream of auditory and/or visual stimuli containing both within- and cross-domain dependencies. Experiment 1 examined within-modal and cross-modal learning across two sensory modalities (audition and vision). Experiment 2 investigated within-categorical and cross-categorical learning across two perceptual categories within the same sensory modality (e.g., shape and color; tones and non-words). Our results indicated that individuals demonstrated learning of the within-modal and within-categorical but not the cross-modal or cross-categorical dependencies. These results stand in contrast to the previous demonstrations of cross-modal statistical learning, and highlight the presence of modality constraints that limit the effectiveness of learning in a multimodal environment.
Theories and possible processes of action in animal assisted interventions

ABSTRACT Different positive effects of interactions with animals, such as reduction of stress reactions, depressive mood, anxiety, aggression, and pain, and promotion of trust, calmness, motivation, and concentration have been documented by research on human–animal interaction (HAI), including animal assisted interventions (AAIs). Potential biological, psychological, and social processes may underpin these effects. Theories of why this may occur include biophilia, anthropomorphism, a focus on the experiential system instead of the verbal-symbolic system, motivation, activation of the oxytocin system, attachment and caregiving including provision of social support for stress buffering, and distraction processes. Understanding how animals may positively affect educational and therapeutic settings, in particular for individuals with psychical and psychosocial challenges, and finding what special indications for AAI exist, and which preconditions of learning in the client or the setting could potentially be enhanced, might provide not only a better rationale for AAIs but also promote their efficacy.
Neonatal mortality, risk factors and causes: a prospective population-based cohort study in urban Pakistan.

OBJECTIVE To evaluate the prevalence, sex distribution and causes of neonatal mortality, as well as its risk factors, in an urban Pakistani population with access to obstetric and neonatal care. METHODS Study area women were enrolled at 20-26 weeks' gestation in a prospective population-based cohort study that was conducted from 2003 to 2005. Physical examinations, antenatal laboratory tests and anthropometric measures were performed, and gestational age was determined by ultrasound to confirm eligibility. Demographic and health data were also collected on pretested study forms by trained female research staff. The women and neonates were seen again within 48 hours postpartum and at day 28 after the birth. All neonatal deaths were reviewed using the Pattinson et al. system to assign obstetric and final causes of death; the circumstances of the death were determined by asking the mother or family and by reviewing hospital records. Frequencies and rates were calculated, and 95% confidence intervals were determined for mortality rates. Relative risks were calculated to evaluate the associations between potential risk factors and neonatal death. Logistic regression models were used to compute adjusted odds ratios. FINDINGS Birth outcomes were ascertained for 1280 (94%) of the 1369 women enrolled. The 28-day neonatal mortality rate was 47.3 per 1000 live births. Preterm birth, Caesarean section and intrapartum complications were associated with neonatal death. Some 45% of the deaths occurred within 48 hours and 73% within the first week. The primary obstetric causes of death were preterm labour (34%) and intrapartum asphyxia (21%). Final causes were classified as immaturity-related (26%), birth asphyxia or hypoxia (26%) and infection (23%). Neither delivery in a health facility nor by health professionals was associated with fewer neonatal deaths. The Caesarean section rate was 19%. Almost all (88%) neonates who died received treatment and 75% died in the hospital. CONCLUSION In an urban population with good access to professional care, we found a high neonatal mortality rate, often due to preventable conditions. These results suggest that, to decrease neonatal mortality, improved health service quality is crucial.
New insights into the stellar content and physical conditions of star-forming galaxies at z = 2-3 from spectral modelling

We have used extensive libraries of model and empirical galaxy spectra [assembled, respectively, from the population synthesis code of Bruzual and Charlot and the fourth data release of the Sloan Digital Sky Survey (SDSS)] to interpret some puzzling features seen in the spectra of high-redshift star-forming galaxies. We show that a stellar He ii λ1640 emission line, produced in the expanding atmospheres of Of and Wolf–Rayet stars, should be detectable with an equivalent width of 0.5–1.5 A in the integrated spectra of star-forming galaxies, provided the metallicity is greater than about half solar. Our models reproduce the strength of the He ii λ1640 line measured in the spectra of Lyman-break galaxies for established values of their metallicities. With better empirical calibrations in local galaxies, this spectral feature has the potential of becoming a useful diagnostic of massive star winds at high, as well as low redshifts. We also uncover a relationship in SDSS galaxies between their location in the [O iii]/Hβ versus [N ii]/Hα diagnostic diagram (the BPT diagram) and their excess specific star formation rate relative to galaxies of similar mass. We infer that an elevated ionization parameter U is at the root of this effect, and propose that this is also the cause of the offset of high-redshift star-forming galaxies in the BPT diagram compared to local ones. We further speculate that higher electron densities and escape fractions of hydrogen ionizing photons may be the factors responsible for the systematically higher values of U in the H ii regions of high-redshift galaxies. The impact of such differences on abundance determinations from strong nebular lines are considered and found to be relatively minor.
Event recognition based on bag of local space-time interest points' features

This paper proposes a novel method based on bag of local space-time interest points' features to recognize and retrieval complex events in real movies. In this method, an individual video sequence is represented as a bag of local space-time features then we integrate such bag-of-feature with SVM for recognition events. Local space-time features are introduced to capture the local events in video and can be adapted to size and velocity of the pattern of the event. To evaluate effectiveness of this method, this paper uses the public Hollywood dataset, in this dataset the shot sequences has collected from 32 different Hollywood movies and it includes 8 event classes. The presented result justify the proposed method explicitly improve the average accuracy and average precision compared to other relative approaches.
Ju n 20 04 Modeling electro-mechanical properties of layered electrets : Application of the finite-element method

We present calculations on the deformation of twoand three-layer electret systems. The electrical field is coupled with the stress-strain equations by means of the Maxwell stress tensor. In the simulations, two-phase systems are considered, and intrinsic relative dielectric permittivity and Young’s modulus of the phases are altered. The numerically calculated electro-mechanical activity is compared to an analytical expression. Simulations are performed on twoand three-layer systems. Various parameters in the model are systematically varied and their influence on the resulting piezoelectricity is estimated. In three-layer systems with bipolar charge, the piezoelectric coefficients exhibit a strong dependence on the elastic moduli of the phases. However, with mono-polar charge, there is no significant piezoelectric effect. A two-dimensional simulation illustrated that higher piezoelectricity coefficients can be obtained for non-uniform surface charges and low Poisson’s ratio of phases. Irregular structures considered exhibit low piezoelectric activity compared to two-layer structures.
Transformed Representations for Convolutional Neural Networks in Diabetic Retinopathy Screening

Convolutional neural networks (CNNs) are flexible, biologically-inspired variants of multi-layer perceptrons that have proven themselves to be exceptionally suited to discriminative vision tasks. However, relatively little is known on whether they can be made both more efficient and more accurate, by introducing suitable transformations that exploit general knowledge of the target classes. We demonstrate this functionality through pre-segmentation of input images with a fast and robust but loose segmentation step, to obtain a set of candidate objects. These objects then undergo a spatial transformation into a reduced space, retaining but a compact high-level representation of their appearance. Additional attributes may be abstracted as raw features that are incorporated after the convolutional phase of the network. Finally, we compare its performance against existing approaches on the challenging problem of detecting lesions in retinal images.