Miracle-dz/UniFAR-FTUs huggingface dataset:
Handbook of Parenting: Theory and Research for Practice

PART ONE: KEY CONCEPTS Parenting - An Introduction - Masud Hoghughi The Social Context of Parenting - David Utting and Gillian Pugh Parenting in Social and Economic Adversity - Christine Puckering Parenting across the Lifespan - Martin Herbert Parental Influences on Vulnerability and Resilience - Carole A Kaplan and Julie Owens Parenting in Culturally Divergent Settings - Lee M Pachter and Thyde Dumont-Mathieu Religious Influences on Parenting - Stephen Frosh Parenting in Restructured and Surrogate Families - Jan Pryor Sexual Orientation and Parenting - Charlotte J Patterson and Erin L Sutfin Grandparenting and Extended Support Networks - Peter K Smith and Linda M Drew PART TWO: FUNCTIONAL AREAS Parenting and Children's Physical Health - Elizabeth Soliday Parenting Chronically Ill Children - The Scope and Impact of Pediatric Parenting Stress - Randi Streisand and Kenneth P Tercyak Parenting Influences on Intellectual Development and Educational Achievement - Sally M Wade Parenting Exceptional Children - Susan McGaw Parenting Anitsocial Behavior - Dana K Smith, Peter G Sprengelmeyer and Kevin J Moore Parenting Antisocial Children and Adolescents - Beth A Kotchick et al Parenting and Mental Health - Colleen S Conley et al Parenting Children with Mental Health Problems - Fiona K Miller and Jennifer M Jenkins PART THREE: PARENT SUPPORT Assessing and Delivering Parent Support - Harriet Heath Community-Based Support for Parents - Judy Hutchings and Carolyn Webster-Stratton Towards a Multi-Level Model of Parenting Intervention - Matthew R Sanders and Alan Ralph E-Parenting - Nicholas Long
Building Mobile Spoken Dialogue Applications Using Regulus

Regulus is an Open Source platform that supports construction of rule-based medium-vocabulary spoken dialogue applications. It has already been used to build several substantial speech-enabled applications, including NASAs Clarissa procedure navigator and Geneva Universitys MedSLT medical speech translator. System like these would be far more useful if they were available on a hand-held device, rather than, as with the present version, on a laptop. In this paper we describe the Open Source framework we have developed, which makes it possible to run Regulus applications on generally available mobile devices, using a distributed client-server architecture that offers transparent and reliable integration with different types of ASR systems. We describe the architecture, an implemented calendar application prototype hosted on a mobile device, and an evaluation. The evaluation shows that performance on the mobile device is as good as performance on a normal desktop PC.
Ieee Transactions on Instrumentation and Measurement Behavioral Models of I/o Ports from Measured Transient Waveforms

This paper addresses the development of accurate and efficient behavioral models of digital IC ports from measured transient responses. The proposed approach is based on the estimation of parametric models from port voltage and current waveforms. The modeling process is described and applied to the modeling of output ports. Its feasibility is demonstrated by the identification of a real device from actual measurements, and by the comparison of the predicted device response with the measured one.
English phonology and morphology

We ilustrate the complexity and interest of English phonology and morphology through two case studies: the phonological and morphological behavior of sibilant suffixes, and the aspiration of voiceless obstruents. We focus on documenting individual variation in these areas and examining theoretical proposals that have been advanced to account for the attested range of variation that is found, highlighting cases where the data connect to larger issues in phonological and morphological theory. keywords: phonology, morphology, English, plural, possessive, aspiration, variation, African American English
Typical Subgraphs of 3- and 4-Connected Graphs

Abstract We prove that, for every positive integer k , there is an integer N such that every 3-connected graph with at least N vertices has a minor isomorphic to the k -spoke wheel or K 3, k ; and that every internally 4-connected graph with at least N vertices has a minor isomorphic to the 2 k -spoke double wheel, the k -rung circular ladder, the k -rung Mobius ladder, or K 4, k . We also prove an analogous result for infinite graphs.
MODERN ORTHODOXY IN POST-SECULAR TIMES

Post-secularism in Israel is expressed, among other ways, by the growing public acceptance of identities that are neither religious nor secular. This paper is predicated on research of individuals located on the boundaries of Orthodox Religious Zionism. It explores their attitudes on a range of issues and argues that they reflect their post-secularist identities. In-depth qualitative interviews were conducted with young men and women who chose to abandon the strictures of a Religious Zionist lifestyle as well as those who still remain within its bounds. Various late-modern and post-secular modes of thought and expression were identified in interviewees’ narratives. These included pluralism, relativism, egalitarianism, the personalization of relationships with God, and a disregard for theological arguments based upon scientific findings. It is argued that these attitudes are related to two late-modern social processes: (1) the rise of individual expressivism and (2) the belief in the liberal human-rights ethic. These tendencies cut across the social divide between interviewees who left Religious Zionism and those who chose to remain within the fold, traversing the previously dominant religious–secular social divide and thus serving as yet another indication for the blossoming of new post-secular spaces in Israeli Jewish society.
Transmembrane Protein 147 (TMEM147) Is a Novel Component of the Nicalin-NOMO Protein Complex*

Nicastrin and its relative Nicalin (Nicastrin-like protein) are both members of larger protein complexes, namely γ-secretase and the Nicalin-NOMO (Nodal modulator) complex. The γ-secretase complex, which contains Presenilin, APH-1, and PEN-2 in addition to Nicastrin, catalyzes the proteolytic cleavage of the transmembrane domain of various proteins including the β-amyloid precursor protein and Notch. Nicalin and its binding partner NOMO form a complex that was shown to modulate Nodal signaling in developing zebrafish embryos. Because its experimentally determined native size (200–220 kDa) could not be satisfyingly explained by the molecular masses of Nicalin (60 kDa) and NOMO (130 kDa), we searched in affinity-purified complex preparations for additional components in the low molecular mass range. A ∼22-kDa protein was isolated and identified by mass spectrometry as transmembrane protein 147 (TMEM147), a novel, highly conserved membrane protein with a putative topology similar to APH-1. Like Nicalin and NOMO, it localizes to the endoplasmic reticulum and is expressed during early zebrafish development. Overexpression and knockdown experiments in cultured cells demonstrate a close relationship between the three proteins and suggest that they are components of the same complex. We present evidence that, similar to γ-secretase, its assembly is hierarchical starting with the formation of a Nicalin-NOMO intermediate. Nicalin appears to represent the limiting factor regulating the assembly rate by stabilizing the other two components. We conclude that TMEM147 is a novel core component of the Nicalin-NOMO complex, further emphasizing its similarity with γ-secretase.
Educational Leadership: Personal Growth for Professional Development

Self-Management and Personal Development Self-Understanding, Personality and Psychometric Instruments Emotional Intelligence 360-Degree Feedback Accelerated Learning, the Brain, Competencies and Interviews Neurolinguistic Programming and Professional Development Improving Communication Skills Developing Creativity, Intuition and Innovation in Schools Managing Stress and Managing Time Career Development and Development as a Professional Training, Coaching and Mentoring Interpersonal Skills, Decision-Making and Team Learning Leadership Development Performance Management Ethics, Values, Vision, Mission and Gender Culture, Change and Organizational Health Strategy Quality Models The Learning Organization and Knowledge Management Business Process Re-Engineering Achieving Radical Change Work and Life Achieving a Balance and Planning for the Future
The frequency in Japanese of genetic variants of 22 proteins III. Phosphoglucomutase‐1, phosphoglucomutase‐2, 6‐phosphogluconate dehydrogenase, adenylate kinase, and adenosine deaminase

Five enzyme systems, PGM1, PGM2, ADA, 6‐PGD and AK, were examined by electrophoresis in over 4000 samples from Hiroshima and Nagasaki for the frequencies of common and rare variants. In the PGM1, system, the PGM21 allele and PGM71; allele were found in polymorphic proportions. I n addition, five kinds of slow variants and three types of fast variants of PGM1 were detected. The PGM3 NGS 11 allele was found in five individuals from Nagasaki, but was not observed in samples from Hiroshima. There were no variants of PGM2. Three kinds of fast variants of 6‐PGD were detected. NO variation in AK was observed. There were no rare variants of ADA. The 6‐PGDc allele had a frequency of 0.084 in Hiroshima, and 0.093 in Nagasaki, and the ADA2 allele frequencies of 0.025 in Hiroshima and 0.032 in Nagasaki.
Biodiversity of metazoan parasites in Acestrorhynchus lacustris ( Lütken , 1875 ) ( Characiformes : Acestrorhynchidae ) from the Batalha River , São Paulo State , Brazil

We collected 32 specimens of peixe-cachorro, Acestrorhyncus lacustris (Lütken, 1875), in a stretch of the Batalha River where there is the formation of a water catchment pond used to supply the local human population, on the boundary between the cities of Bauru and Piratininga, SP, from May to September 2013 aiming to conduct a qualitative and quantitative study of its metazoan parasites. A total of 14 parasites species were collected and identified: Diaphorocleidus sp. , Austrodiplostomum compactum, Bellumcorpus major, Rhipidocotyle santanaensis, R. gibsoni, Capillariidae gen. sp. , Contracaecum sp. , Goezia brasiliensis, Guyanema raphiodoni, Travassosnema travassosi, Philometroides caudata, Spiroxys contortus, Heliconema sp. and Procamallanus (Spirocamallanus) inopinatus. The parasite community was characterized by high diversity (HB = 1.42 ± 0.43) highlighting the nematodes, which represented the majority of the collected parasites. Travassosnema travassosi was the dominant species (frequency dominance = 53.1% and relative dominance = 0.3 ± 0.1). The parasites showed the aggregate distribution pattern, and only A. compactum showed a random distribution pattern. It is the first record of the species A. compactum, B. major, Capillariidae gen. sp. , G. brasiliensis, G. raphiodoni, S. contortus and Heliconema sp. for this host.
Structure, energetics, and dynamics of lipid–protein interactions: A molecular dynamics study of the gramicidin A channel in a DMPC bilayer

The microscopic details of lipid–protein interactions are examined using molecular dynamics simulations of the gramicidin A channel embedded in a fully hydrated dimyristoyl phosphatidylcholine (DMPC) bilayer. A novel construction protocol was used to assemble the initial configurations of the membrane protein complex for the simulations. Three hundreds systems were constructed with different initial lipid placement and conformations. Seven systems were simulated with molecular dynamics. One system was simulated for a total of 600 psec, four were simulated for 300 psec, and two for 100 psec. Analysis of the resulting trajectories shows that the bulk solvent–membrane interface region is much broader than traditionally pictured in simplified continuum theories: its width is almost 15 Å. In addition, lipid–protein interactions are far more varied, both structurally and energetically, than is usually assumed: the total interaction energy between the gramicidin A and the individual lipids varies from 0 to −50 kcal/mol. The deuterium quadrupolar splittings of the lipid acyl chains calculated from the trajectories are in good agreement with experimental data. The lipid chains in direct contact with the GA are ordered but the effect is not uniform due to the irregular surface of the protein. Energy decompositions shows that the most energetically favorable interactions between lipid and protein involve nearly equal contributions from van der Waals and electrostatic interactions. The tryptophans, located near the bulk–membrane interface, appear to be particularly important in mediating both hydrogen bonding interactions with the lipid glycerol backbone and water and also in forming favorable van der Waals contacts with the hydrocarbon chains. In contrast, the interactions of the leucine residues with the lipids, also located near the interface, are dominated by van der Waals interactions with the hydrocarbon lipid chains.
Adult learning in modern societies : an international comparison from a life-course perspective

Aava, K. 163 Abadie, A. 57 D’Addio, A.C. 351 Adult Education Survey (AES, 2007) 29, 39, 48, 270 see also surveys adult learning see Australia; Czech Republic; Denmark; Finland; Germany; Great Britain; Hungary; Italy; modern societies; Russia; Spain; Sweden and US context adult learning, labor market outcomes and social inequalities in modern societies (and) 3–26 macro-level changes and increased need for adult learning 5–7 demographic aging and increasing labor shortages 6–7 economic change under globalization 5–6 role of national institutional settings see national institutional settings social inequality see subject entry adult learning, state support for 15–16, 143, 186, 266 Ahonen, K. 205 Akhmedov, A. 156 Albert, C. 11, 35, 36, 42, 169 Alburg, D.A. 85, 86 Allmendinger, J. 142, 144, 243, 372 Almeida, R.K. 37, 42 Altonji, G. 86, 87 Altorjai, S. 266 Amatori, F. 331 Andersen, R. 101 Andersen, T. 323 Andersen, T.M. 224, 225, 226 Angrist, J. 57 Antikainen, A. 15 Armed Forces Qualification Test (AFQT) 89, 91 Arrazola, M. 312 Arts, W. 33 Arulampalam, W. 36, 66, 123 Ashenfelter, O. 169 Aterido, R. 37, 42 Australia, adult learning in: predictors and outcomes (and) 98–118 see also surveys analytic strategy 106 contextual variables for 105 control variables for 104 data for 103 demographic variables for 105 discussion and conclusion 114 key variables for 103–4 research aims for 102 results 107–14 work-related variables for 105 Australia(n) 353, 354, 359, 360, 361, 363, 364, 365 Higher Education Contribution Scheme (HECS) 99 labor market in 99–100 lifelong learning in 100–101 participation in adult education 101–2 welfare state 99 Australia and New Zealand: Standard Classification of Occupations 105 Austria 29, 33, 265, 284, 354 Autor, D.H. 190, 201 Axelsson, R. 190
Microalbuminuria in Type-2 Diabetes Mellitus; the tip of iceberg of diabetic complications

Objective: To determine the prevalence of microalbuminuria and its association with hypertension and other diabetic complications among Type-2 diabetic patients attending at Aga Khan University Hospital Karachi. Methods: 1280 Type-2 diabetes patients who visited the outpatient department of Aga Khan University Hospital from September 2014 to August 2016 were included in the study. Microalbuminuria was diagnosed if spot urinary microalbumin excretion was confirmed to be more than 20mg/l. Hypertension was diagnosed if BP >140/90 or already on antihypertensive medications. Other demographic, clinical and laboratory data were also recorded. Results: Microalbuminuria was diagnosed in 404(31.56%) patients and among these albuminuric patients 335(82.9%) had hypertension. They were also dyslipidemic, having raised triglyceride levels, lower HDL levels, with more prevalence of background diabetic retinopathy and peripheral neuropathy. They also showed higher HbA1C levels and longer duration of diabetes. Conclusion: The prevalence of the microalbuminuria in our patients with Type-2 diabetes is 31.56% and is not only an early sign of diabetic nephropathy but also a host of other diabetic complications and should be dealt early with strict control of their hyperglycemia and hypertension to help prevent the future complications.
Prevalence and harm perceptions of various tobacco products among college students.

INTRODUCTION Although use of non-cigarette alternative tobacco products (ATPs) is increasingly prevalent in the United States, little is known about the varying patterns of tobacco use among college students. This study examined prevalence of ATP use and differences across 4 groups of students (nontobacco, cigarette-only, polytobacco, and ATP-only users) on perceptions of danger and beliefs about government safety evaluation of tobacco products. METHODS An online survey was administered to 5,028 students attending 7 public universities within a larger university system (M age = 20.5 years, 59.6% female, 54.6% Hispanic/Latino). Multivariate analyses were conducted to investigate differences between the 4 groups on perceived danger of tobacco products and beliefs regarding government safety evaluation of these products. RESULTS Prevalence of ATP use among the sample ranged from 0.4% for dissolvable tobacco to 10.8% for hookah. Group membership was significantly associated with perceived danger of each tobacco product, whereby cigarette-only and ATP-only users reported significantly higher levels of perceived danger for most ATPs than did polytobacco users. Furthermore, cigarette-only, polytobacco, and ATP-only users were significantly more likely than nonusers to believe that the government evaluates some tobacco products for safety. CONCLUSIONS ATP use among young adult college students is prevalent. Furthermore, students who use ATPs in conjunction with cigarettes (i.e., polytobacco users) appear to be at highest risk for the continuation and subsequent dependence on nicotine, given their danger perceptions and beliefs of government evaluation. Future research examining trajectories of use, particularly among polytobacco users, is needed.
Cost-Effectiveness of Health Coaching: An Integrative Review

Purpose/Objectives: The purpose of this review was to evaluate published literature to distinguish how health coaching influences the cost of chronic disease management in insured adults with chronic conditions. Primary Practice Setting: An integrated literature review was conducted. MEDLINE, Business Source Complete, and OneSearch were searched for the years 2001–2016 utilizing the following key words: health coaching, health coaching AND insurance companies, health coaching AND cost, health coaching AND health insurance, and health coaching AND insurance cost. A total of 67 articles met inclusion criteria and were assessed for applicability. Of those, 27 articles were found to be relevant to the research question. The practice settings of these articles are mostly primary care and wellness programs. Findings/Conclusions: Throughout the literature, health coaching has been found effective in chronic disease management such as hypertension, diabetes, and hyperlipidemia. Studies evaluating the cost-effectiveness of health coaching are limited. The current literature does not clearly demonstrate that health coaching lowers expenditures and patient copayments in the short term but projects future savings. Implications for Case Management Practice: Health coaching has the potential to improve chronic disease management and lower health care expenditures. Further long-term research is needed to evaluate the cost-effectiveness of health coaching. It has been projected that the cost-effectiveness of health coaching will be long-term or over 12 months after initiating the health coaching program.
Second-generation method for analysis of chromatin binding using formaldehyde crosslinking kinetics

Formaldehyde crosslinking underpins many of the most commonly used experimental approaches in the chromatin field, especially in capturing site-specific protein-DNA interactions. Extending such assays to assess the stability and binding kinetics of protein-DNA interactions is more challenging, requiring absolute measurements with a relatively high degree of physical precision. We previously described an experimental framework called CLK, which uses time-dependent formaldehyde crosslinking data to extract chromatin binding kinetic parameters. Many aspects of formaldehyde behavior in cells are unknown or undocumented, however, and could potentially impact analyses of CLK data. Here we report biochemical results that better define the properties of formaldehyde crosslinking in budding yeast cells. These results have the potential to inform interpretations of ‘standard’ chromatin assays including chromatin immunoprecipitation, and the chemical complexity we uncovered resulted in the development of an improved method for measuring binding kinetics using the CLK approach. Optimum conditions included an increased formaldehyde concentration and more robust glycine quench conditions. Notably, we find that formaldehyde crosslinking rates can vary dramatically for different protein-DNA interactions in vivo. Some interactions were crosslinked much faster than the time scale for macromolecular interaction, making them suitable for kinetic analysis. For other interactions, we find the crosslinking reaction occurred on the same time scale or slower than binding dynamics; for these it was in some cases possible to compute the in vivo equilibrium-binding constant but not on- and off-rates for binding. Selected TATA-binding protein-promoter interactions displayed dynamic behavior on the minute to several minutes time scale.
La práctica educativa intercultural en Secundaria

Este articulo describe los resultados de la investigacion llevada a cabo por la Universidad de Leon, desde el Departamento de Didactica General, Especificas y Teoria de la Educacion, de la Facultad de Educacion, cofinanciado por el Ministerio de Trabajo e Inmigracion y la Junta de Castilla y Leon, junto con el Ayuntamiento de Leon, dentro del proyecto “Construyendo Ciudadania”, cuyo objetivo ha sido conocer la opinion y actitud que tienen los equipos directivos de los Institutos de Educacion Secundaria (IES) de la ciudad de Leon sobre las practicas y estrategias de educacion intercultural que se estan desarrollando en sus centros educativos y los resultados que las mismas estan teniendo de cara a una mejor convivencia e integracion de todo el alumnado. En la investigacion han participado todos los equipos directivos de los IES de Leon, asi como los coordinadores y coordinadoras de convivencia de dichos institutos. Se realizo mediante una exhaustiva y rigurosa entrevista grupal en profundidad semiestructurada, con cada uno de los equipos de cada IES, que consta de 35 cuestiones abiertas, estructuradas en 6 categorias, relacionadas con la situacion existente en cada centro respecto a la multiculturalidad, la filosofia y practicas de educacion intercultural que desarrollan, los recursos con los que cuentan, el abordaje curricular y organizativo de la educacion intercultural y la formacion que ha recibido el profesorado. Asi, encontramos que aunque se ha incorporado el concepto de educacion intercultural en el discurso educativo, el enfoque y las actuaciones concretas desarrolladas en los IES se centra mas en el modelo de compensacion educativa.
Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma

The use of either mitotane or chemotherapy in the treatment of advanced adrenocortical carcinoma (ACC) has led to scanty and controversial results. The recent finding that mitotane is able to reverse in vitro multidrug resistance has provided a rational basis for combining this agent with cytotoxic drugs. The association of mitotane with etoposide, doxorubicin, and cisplatin (EDP) in the treatment of patients with advanced, inoperable ACC was tested in an Italian multicenter Phase II trial.