Miracle-dz/UniFAR-FTUs huggingface dataset:
MindNavigator: Exploring the Stress and Self-Interventions for Mental Wellness

Mental wellness is a desirable health outcome for students. However, current personal informatics systems do not adequately support students in creating concrete mental health-related goals and turning them into actionable plans. In this paper, we introduce MindNavigator - a workshop in which groups of college students were invited to generate behavioral change goals to manage daily life stress and practice personalized interventions for two weeks. We describe the manner in which participants identified both stressors and pleasures to create actionable, engaging, and open-ended behavioral plans that aided in stress relief. We found that the social nature of the workshop helped participants understand themselves and execute self-intervention in new ways. Through this practice, we build on prior studies to propose an analytical framework of personal informatics for mental wellness.
Delayed Effect of Blood Flow–restricted Resistance Training on Rapid Force Capacity

Purpose The aim of the present study was to investigate the effect and time course of high-frequent low-load blood flow–restricted (BFR) resistance training on rapid force capacity (i.e., rate of torque development [RTD]). Materials and Methods Ten male subjects (22.8 ± 2.3 yr) performed four sets of knee extensor exercise (20% one-repetition maximum) to concentric failure during concurrent BFR of the thigh (100 mm Hg), and eight work-matched controls (21.9 ± 3.0 yr) trained without BFR (CON). Twenty-three training sessions were performed within 19 d. Maximal slow and fast knee joint velocity muscle strength and rapid force capacity (e.g., RTD) and evoked twitch contractile parameters were assessed before (Pre) and 5 and 12 d after (Post5 and Post12) training. Muscle biopsies were obtained Pre, after 8 d (Mid8), and 3 and 10 d after (Post3 and Post10) training to examine changes in myofiber area and expression of myocellular proteins known to be modified by cellular stress (CaMKII, annexin A6, SNO-CYS). Results RTD remained unchanged after BFR training at Post5, while increasing 15%–20% Post12 (P < 0.01). Evoked muscle twitch parameters showed a general decline Post5 (P < 0.01) while returning to baseline levels at Post12. All contractile parameters essentially remained unchanged in CON. Elevated CaMKII was observed with BFR training at Post3 (57%) and Post10 (71%) (P < 0.05), whereas SNO-CYS increased in CON at Mid8 (P < 0.05). Conclusion This study is the first to show that low-load resistance exercise performed with BFR leads to marked increases in rapid force capacity (RTD). However, a general delayed adaptive response was observed for voluntary contractile parameters (including RTD) in parallel with a decline and subsequent recovery in evoked contractile properties, suggesting the delayed gain in rapid force capacity mainly have a peripheral origin.
Proteomic analysis provides new insights into the adaptive response of a dinoflagellate Prorocentrum donghaiense to changing ambient nitrogen.

Nitrogen (N) is the major nutrient limiting phytoplankton growth and productivity over large ocean areas. Dinoflagellates are important primary producers and major causative agents of harmful algal blooms in the ocean. However, very little is known about their adaptive response to changing ambient N. Here, we compared the protein profiles of a marine dinoflagellate Prorocentrum donghaiense grown in inorganic N-replete, N-deplete and N-resupplied conditions using 2-D fluorescence differential gel electrophoresis. The results showed that cell density, chlorophyll a and particulate organic N contents presented low levels in N-deplete cells, while particulate organic carbon content and glutamine synthetase (GS) activity maintained high levels. Comparison of the protein profiles of N-replete, N-deplete and N-resupplied cells indicated that proteins involved in photosynthesis, carbon fixation, protein and lipid synthesis were down-regulated, while proteins participating in N reallocation and transport activity were up-regulated in N-deplete cells. High expressions of GS and 60 kDa chaperonin as well as high GS activity in N-deplete cells indicated their central role in N stress adaptation. Overall, in contrast with other photosynthetic eukaryotic algae, P. donghaiense possessed a specific ability to regulate intracellular carbon and N metabolism in response to extreme ambient N deficiency.
Estimation of Hurricane Maximum Wind Speed Using Temperature Anomaly Derived From Advanced Technology Microwave Sounder

Estimation of hurricane intensity is typically relying on aircraft observations and remote sensing data. This letter develops a satellite algorithm to estimate the hurricane surface maximum wind speed. The Advanced Technology Microwave Sounder (ATMS) observations are used to retrieve the atmospheric temperatures. The temperature anomaly field at each pressure level within the hurricane is derived with respect to its environment. It is shown that for a tropical cyclone entering the hurricane stage, a warm core anomaly occurs in upper troposphere. From the GPS dropsonde data of three hurricane cases (Harvey, Irma, and Maria) in 2017, a linear relationship is derived between the maximum warm core value and maximum surface wind speed. Thus, ATMS-derived warm core anomaly is a very good indicator of storm intensity and can be used in the operational weather forecasts.
THE EVOLUTIONARY STRATEGY OF THE EQUIDAE AND THE ORIGINS OF RUMEN AND CECAL DIGESTION

There are two main groups of ungulates or hoofed mammals living today, perissodactyls and artiodactyls. They are distinguished by a basic difference in foot morphology, which indicates that the two groups arose independently from a basal "proto-ungulate" stock (the order Condylarthra) in the early Tertiary. This difference involves the axis of symmetry of the foot. In perissodactyls it passes through the third metapodial, while in artiodactyls it passes between the third and fourth metapodials. The perissodactyls surviving today are horses, rhinos and tapirs. The recent artiodactyls are a much larger and more diverse group, broadly covering all "cloven-hoofed" animals such as pigs, hippos, camels, deer, giraffes, antelope, cattle and sheep. The perissodactyls must have evolved by the late Paleocene, as by the early Eocene four out of five of the known superfamilies are already distinguishable (Romer, 1966). Artiodactyls are also seen in the early Eocene (Romer, 1966), but the two major groups of ruminant artiodactyls, the tylopods and the pecorans, do not appear in the fossil record until the late Eocene (Gazin, 1955) (see Fig. 1). The perissodactyls were the dominant medium to largesized herbivores during the Eocene, and in the early Oligocene a reduction in their diversity coincided with the beginning radiations of the ruminant groups of artiodactyls. These latter animals were the dominant medium-sized herbivores throughout the remainder of the Tertiary, at least in terms of species diversity. The perissodactyls originated in North America; the origin of the artiodactyls, whether in North America or in Eurasia, is still in question (Olson, 1971). As the rise of the artiodactyls at the Eocene-Oligocene boundary coincides with the decrease in the diversity of the perissodactyls, theories have been advanced to explain this coincidence in terms of perissodactyls being competitively inferior to artiodactyls. One obvious difference between the two groups is the difference in limb morphology. Although the axis of symmetry of the foot seems an unlikely candidate for conferring a selective advantage, artiodactyls do possess a unique double trochleared tarsal or ankle joint. This structure has been regarded as a key feature of the group and contributory to their evolutionary success, on the grounds that it has enabled artiodactyls to achieve rapid acceleration for predator escape (e.g., Schaeffer, 1947; Romer, 1968; Colbert, 1969). While there is little doubt that this particular adaptation was of value to the artiodactyls themselves, I do not think, however, that it had a great deal to do with the relative competitive efficiencies of these two ungulate groups. For a start, this tarsus appeared in a highly advanced condition in the first artiodactyls in the early Eocene (Schaeffer, 1947) long before their radiation and diversification, and is found in noncursorial as well as cursorial forms. In addition, modern ecological work demonstrates that predation is not necessarily detrimental
Renal oxidative stress and renal CD8+ T-cell infiltration in mercuric chloride-induced nephropathy in rats: role of angiotensin II

Abstract Mercuric chloride (HgCl2) induces kidney damage, in part, through oxidative stress. A role for angiotensin II (Ang II) in pro-inflammatory events in a model of acute HgCl2-induced nephropathy was reported. Ang II is a potent oxidative stress inducer; however, its role in oxidative/anti-oxidative events in HgCl2-induced nephropathy remains unknown. The aim of this study was to determine the role of Ang II in the oxidative stress and renal infiltration of CD8+ T-cells after an acute HgCl2 intoxication. Three groups of Sprague Dawley rats were treated with a single subcutaneous dose of 2.5 mg/kg HgCl2: for 3 days prior to and for 4 days after that injection, rats in one group received Losartan (30 mg/kg), in another group Enalapril (30 mg/kg) or normal saline in the last group. Two other groups of drug-treated rats received saline in place of HgCl2. A final group of rats received saline in place of HgCl2 and the test drugs. All treatments were via gastric gavage. At 96 h after the vehicle/HgCl2 injection, blood and kidney samples were harvested. Renal sections were homogenized for measures of malondialdehyde (MDA), reduced glutathione (GSH) and catalase activity. Frozen sections were studied for the presence of superoxide anion () and CD8+ T-cells. HgCl2-treated rats had increased interstitial and tubular expression of , high levels of MDA, normal catalase activity and GSH content, increased levels of interstitial CD8+ T-cells and an increased percentage of necrotic tubules. Anti-Ang II treatments diminished the HgCl2-induced increases in interstitial , CD8+ T-cells and tubular damage and increased catalase and GSH expression above that due to HgCl2 alone; the HgCl2-induced high MDA levels were unaffected by the drugs. These data provide new information regarding the potential role of Ang II in the oxidative stress and renal CD8+ T-cell infiltration that occur during HgCl2 nephropathy.
In Vitro Calcite Crystal Morphology Is Modulated by Otoconial Proteins Otolin-1 and Otoconin-90

Otoconia are formed embryonically and are instrumental in detecting linear acceleration and gravity. Degeneration and fragmentation of otoconia in elderly patients leads to imbalance resulting in higher frequency of falls that are positively correlated with the incidence of bone fractures and death. In this work we investigate the roles otoconial proteins Otolin-1 and Otoconin 90 (OC90) perform in the formation of otoconia. We demonstrate by rotary shadowing and atomic force microscopy (AFM) experiments that Otolin-1 forms homomeric protein complexes and self-assembled networks supporting the hypothesis that Otolin-1 serves as a scaffold protein of otoconia. Our calcium carbonate crystal growth data demonstrate that Otolin-1 and OC90 modulate in vitro calcite crystal morphology but neither protein is sufficient to produce the shape of otoconia. Coadministration of these proteins produces synergistic effects on crystal morphology that contribute to morphology resembling otoconia.
Towards Algorithmic Experience: Initial Efforts for Social Media Contexts

Algorithms influence most of our daily activities, decisions, and they guide our behaviors. It has been argued that algorithms even have a direct impact on democratic societies. Human - Computer Interaction research needs to develop analytical tools for describing the interaction with, and experience of algorithms. Based on user participatory workshops focused on scrutinizing Facebook's newsfeed, an algorithm-influenced social media, we propose the concept of Algorithmic Experience (AX) as an analytic framing for making the interaction with and experience of algorithms explicit. Connecting it to design, we articulate five functional categories of AX that are particularly important to cater for in social media: profiling transparency and management, algorithmic awareness and control, and selective algorithmic memory.
Empowerment in HCI - A Survey and Framework

Empowering people through technology is of increasing concern in the HCI community. However, there are different interpretations of empowerment, which diverge substantially. The same term thus describes an entire spectrum of research endeavours and goals. This conceptual unclarity hinders the development of a meaningful discourse and exchange. To better understand what empowerment means in our community, we reviewed 54 CHI full papers using the terms empower and empowerment. Based on our analysis and informed by prior writings on power and empowerment, we construct a framework that serves as a lens to analyze notions of empowerment in current HCI research. Finally, we discuss the implications of these notions of empowerment on approaches to technology design and offer recommendations for future work. With this analysis, we hope to add structure and terminological clarity to this growing and important facet of HCI research.
Experimental Study for the Determination of the Material Diameter of the Riprap Bed Protection

Bed protection in apron downstream was installed to use riprap or gabion mattress. In the case of bed protection using riprap, the decision on the riprap diameter is very important because riprap diameter means the capacity to withstand the flow. Initial formulas for the decision on the riprap diameter applied velocity and weight as main factors. Since the main factors gradually expanded to depth, bed slope, and turbulence intensity, decision formulas for the riprap diameter were detailed. Because turbulence intensity was considered to be a main factor of the formula, the decision formulas for the riprap diameter could be expanded to apply to bed protection around hydraulic structures. Escarameia and May conducted a study on the riprap diameter of a strong turbulence area around the downstream of hydraulic structures. For the formula of Escarameia and May, the basis of the formula was the Izbash type, and the main factor was turbulence intensity. This study was an experimental study for deciding the riprap diameter installed around apron downstream and was based on the study results of Escarameia and May. The experiment measured the velocity upon change of discharge and riprap diameter to the installed weir model and analyzed the correlation of threshold velocity by diameter. The experimental formula in this study expanded the turbulence intensity limits of the Escarameia and May formula and increased application to turbulence intensity in weir downstream.
Modulation of Ka-Band Doppler Radar Signals Backscattered From the Sea Surface

This paper presents dual copolarized (VV and HH) Ka-band radar measurements of joint modulation of normalized radar cross section (NRCS) and Doppler velocity (DV) performed from a sea research platform. NRCS and DV modulations are well correlated. NRCS modulations exhibit a spiky structure. HH modulations are stronger than VV ones leading to modulations of the polarization ratio. This suggests that an important portion of NRCS modulations is produced by nonpolarized radar returns from modulated wave breaking facets. DV modulations reveal that at incidence angles <50°, NRCS spikes are attributable to rather slow moving facets, which may be interpreted as short wave breaking disturbances embedded in the water at crests of modulating waves. Using the DV as a proxy for wave gauge, a modulation transfer function (MTF) is estimated for both polarizations. The hydrodynamics component of the total MTF, hydro-MTF, combines NRCS modulations supported by Bragg waves and wave breaking. The contribution of each type of facets to the hydro-MTF is weighted by its partial contribution to the NRCS, and thus, hydro-MTF becomes dependent on radar polarization. Using hydro-MTF for HH and VV, Bragg wave and wave breaking modulations are separated. Wave breaking modulations are significant, with MTF amplitude varying from 5 to about 30 depending on wind speed. Ka-band Bragg waves are strongly modulated at low winds, but their modulation almost vanishes at moderate winds. Finally, we propose an empirical MTF parameterization based on polynomial fitting as a function of observation geometry and wind.
Minimax Rényi Redundancy

The redundancy for universal lossless compression of discrete memoryless sources in Campbell’s setting is characterized as a minimax Rényi divergence, which is shown to be equal to the maximal <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula>-mutual information via a generalized redundancy-capacity theorem. Special attention is placed on the analysis of the asymptotics of minimax Rényi divergence, which is determined up to a term vanishing in blocklength.
Fundamental processes of protein folding: Measuring the energetic balance between helix formation and hydrophobic interactions

Theories of protein folding often consider contributions from three fundamental elements: loops, hydrophobic interactions, and secondary structures. The pathway of protein folding, the rate of folding, and the final folded structure should be predictable if the energetic contributions to folding of these fundamental factors were properly understood. αtα is a helix‐turn‐helix peptide that was developed by de novo design to provide a model system for the study of these important elements of protein folding. Hydrogen exchange experiments were performed on selectively 15N‐labeled αtα and used to calculate the stability of hydrogen bonds within the peptide. The resulting pattern of hydrogen bond stability was analyzed using a version of Lifson‐Roig model that was extended to include a statistical parameter for tertiary interactions. This parameter, x, represents the additional statistical weight conferred upon a helical state by a tertiary contact. The hydrogen exchange data is most closely fit by the XHC model with an x parameter of 9.25. Thus the statistical weight of a hydrophobic tertiary contact is ∼5.8× the statistical weight for helix formation by alanine. The value for the x parameter derived from this study should provide a basis for the understanding of the relationship between hydrophobic cluster formation and secondary structure formation during the early stages of protein folding.
The Relationship Between Regulatory Emotional Self-Efficacy and Core Self-Evaluation of College Students: The Mediation Effects of Suicidal Attitude

This study analyzed the mediation effect of a suicidal attitude from regulatory emotional self-efficacy to core self-evaluation. A measurement study was conducted among 438 college students using the Regulatory Emotional Self-Efficacy Scale, the Core Self-Evaluation Scale, and the Suicide Attitude Questionnaire. Results from the plug-in process in SPSS and the bootstrap method showed that the attitude toward suicidal behavior and the attitude toward family members of an individual who has committed suicide played a double-mediation role, from perceived self-efficacy in managing happiness to core self-evaluation. The results also showed that the attitude toward a person who committed suicide or attempted suicide played a mediation effect from perceived self-efficacy in managing curiousness to core self-evaluation. This research has great significance for improving the understanding of college students’ sense of happiness and prevention for self-evaluation.
HPV16 and HPV18 genotyping triage in young women with borderline cytology or mild dyskaryosis: effect of age on genotype‐specific risk of high‐grade CIN

Human papillomavirus (HPV) triage of borderline cytology or mild dyskaryosis is limited by the higher prevalence of HPV in women with these findings relative to those with high‐grade cervical intraepithelial neoplasia (≥CIN2). This is particularly relevant in young women in whom HPV prevalence is discernible. In a previous analysis of HPV triage and colposcopy outcomes in Northern Ireland, we revealed a substantial amount of prevalent high‐grade disease in women below 30 years of age. We explored the role of genotyping for HPV16/HPV18 in this population by assessing the risk of high‐grade lesions associated with these genotypes and the effect of age on type‐specific risk.
Development of controlled release formulations of azadirachtin-A employing poly(ethylene glycol) based amphiphilic copolymers

Controlled release (CR) formulations of azadirachtin-A, a bioactive constituent derived from the seed of Azadirachta indica A. Juss (Meliaceae), have been prepared using commercially available polyvinyl chloride, polyethylene glycol (PEG) and laboratory synthesized poly ethylene glycol–based amphiphilic copolymers. Copolymers of polyethylene glycol and various dimethyl esters, which self assemble into nano micellar aggregates in aqueous media, have been synthesized. The kinetics of azadirachtin-A, release in water from the different formulations was studied. Release from the commercial polyethylene glycol (PEG) formulation was faster than the other CR formulations. The rate of release of encapsulated azadirachtin-A from nano micellar aggregates is reduced by increasing the molecular weight of PEG. The diffusion exponent (n value) of azadirachtin-A, in water ranged from 0.47 to 1.18 in the tested formulations. The release was diffusion controlled with a half release time (t1/2) of 3.05 to 42.80 days in water from different matrices. The results suggest that depending upon the polymer matrix used, the application rate of azadirachtin-A can be optimized to achieve insect control at the desired level and period.
Hospice at home

On Friday 31 December 1993 my husband abandoned his car in heavy traffic and jogged the last three miles to his surgical outpatients session. He collided with a lamp post, fracturing two ribs and sustaining a moderately severe head injury, and was found by a hospital porter, wandering confused near the canal beside the hospital. It was the end of months of lurking anxiety about his health—extreme fatigue had been attributed either to his excessive workload or to our new addition to the family. Three short lived episodes of unilateral visual loss in the summer had not recurred, and although his ophthalmologist was concerned about the finding of optic vein hypertension, magnetic resonance imaging of the brain in September was entirely normal. More alarming were the strange attacks I had witnessed: a metallic taste in the mouth, sweating, terror, and collapse without loss of consciousness. Yet all measurements were normal: pulse the usual 45, blood pressure 130/80, BM sticks normal, reflexes brisk and equal. A general physician consulted in December could find no cause and diagnosed overwork, excessive exercise, and poor eating habits. Temporary elation propelled me into Christmas preparations as I gratefully chose presents for my precious husband. But deep suspicion remained and lifestyle changes were not easy to make, so the call from the accident and emergency consultant telling me of Adrian's accident came as no great surprise. I was almost relieved. While I finished my surgery, Adrian's condition deteriorated and computed tomography was performed. Meeting …