Miracle-dz/UniFAR-FTUs huggingface dataset:
Spontaneous Healing of a Patellar Tendon Anterior Cruciate Ligament Graft: A Case Report

Revision surgery has become increasingly common in instances of failed ACL reconstruction. At our institution, in the last 2 years, we have performed revision ACL surgery on 25 patients whose primary ACL reconstruction had failed. It has proven difficult (if not impossible) to achieve results of revision surgery similar to those of primary ACL reconstruction. Multiple studies have shown the poor potential for primary healing in cases of complete rupture of the ACL. However, we report a case of a patient whose primary ACL reconstruction failed due to traumatic rupture of the patellar tendon graft and who went on to demonstrate primary healing of the graft in the interim between the diagnostic arthroscopic procedure and the planned revision surgery.
Author's Personal Copy Dynamics of Atmospheres and Oceans Impact of Interactive Westerly Wind Bursts on Ccsm3 Author's Personal Copy

In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a b s t r a c t Westerly wind bursts or events (WWBs or WWEs) are commonly viewed as stochastic processes, independent of any oceanic forcing. Some recent work and observations have suggested that these events can be viewed as state-dependent noise in that they are modulated by the SST variability. This potentially affects the predictability of the El Niño Southern Oscillation (ENSO). In this study, we examine the impact of parameterized WWBs on ENSO variability in the Community Climate System Model version 3.0 and 4.0 (CCSM3 and CCSM4). The WWBs parameterization is derived based on 50 years of atmospheric reanalysis data and observed estimates of tropical Pacific SST. To study the impact of WWBs three experiments are performed. In the first experiment, the model is integrated for several hundred years with no prescribed WWBs events (i.e. the control). In the second case, state-independent WWBs events are introduced. In other words, the occurrence, location , duration, and scale of the WWBs are determined (within bounds) randomly. These wind events are always positive (eastward) without a westward counterpart and are totally independent of the anomalies in the state variables, and can be thought of as additive noise. For the third case, the WWBs are introduced but as multiplicative noise or state-dependent forcing, modulated by SST anomalies. The statistical moments for the Niño 3.4 index shows that the state-dependent case produced larger El Niño Southern Oscillation (ENSO) events and the bias toward stronger cold events is reduced as compared to the control and the state-independent runs. There is very little difference between the control and the state-independent WWB simulations suggesting that the deterministic component of the burst is responsible for reshaping the ENSO events. Lag-lead correlation of ocean variables with Niño 3.4 index suggests larger temporal coherence of the ENSO events. This, along with SSTA composites, also suggest a shift toward a more self sustained mechanism as the experiments progress from the control to the state dependent WWBs. Overall, the parameterized WWBs have the capability to modify the ENSO regime in the CGCM, demonstrating the importance of sub-seasonal variability on interannual time scales. The fast varying (stochastic) component of WWB is …
Effect of 24-hour corneal biomechanical changes on intraocular pressure measurement.

PURPOSE To study 24-hour changes of corneal biomechanical properties and their influences on measurement of intraocular pressure (IOP). METHODS Fifteen healthy young volunteers (age range, 20-25 years) were housed for 1 day in a sleep laboratory. Sitting and supine central corneal thickness (CCT) were measured every 2 hours with an ultrasonic pachymeter. Sitting IOP and corneal hysteresis, an indicator of viscoelasticity, were measured with a noncontact tonometer. RESULTS There were consistent 24-hour variations of CCT and IOP for the group. Nocturnal mean CCT and nocturnal mean IOP were significantly higher than the diurnal mean CCT and diurnal mean IOP, respectively. The peak CCT occurred at 1:30 to 5:30 AM and the trough CCT at 1:30 PM. The peak IOP occurred at 5:30 AM and the trough IOP at 9:30 PM. Cosine fits of each subject's 24-hour CCT and IOP data showed synchronized rhythms. The phase timing of 24-hour CCT rhythm was significantly earlier than the phase timing of 24-hour IOP rhythm. Twenty-four-hour variation of corneal hysteresis was inconsistent and cosine fits of 24-hour data of corneal hysteresis did not display a 24-hour rhythm. CONCLUSIONS In healthy young adults, CCT was thicker, and IOP was higher during the nocturnal period than during the diurnal period. Nocturnal peak CCT occurred a few hours earlier than did nocturnal peak IOP. The twenty-four-hour change in corneal viscoelasticity was not significant. There was no evidence that the 24-hour change in IOP was due to the change in corneal biomechanical properties.
The origin of sporadic gastrinomas within the gastrinoma triangle: a theory.

Sporadic gastrinomas are found predominantly within the gastrinoma triangle (85%), frequently within lymph nodes in the triangle (40%) and often multiple (40%). In addition, they are homologous with pancreatic polypeptidomas and express pancreatic polypeptide. We hypothesized that, if gastrinomas were of ventral pancreatic bud origin, several (7) predictions could be made. The data from the investigation of these predictions have supported the theory. We postulate that sporadic gastrinomas in the triangle arise from stem cells from the ventral pancreatic bud that become dispersed and incorporated into lymph tissue and the duodenal wall during the ventral bud's embryonic dorsal rotation within the area of the triangle.
Computerized Stroop Test to Assess Selective Attention in Children with Attention Deficit Hyperactivity Disorder

Research shows abnormal function of the pre-frontal cortex in Attention Deficit Hyperactivity Disorder (ADHD). This cortex is involved in the control of executive functions related to planning and execution of goal-oriented strategies, working memory, inhibitions, cognitive flexibility, and selective attention. Selective attention involves focus on the target stimulus, ignoring competing distractions. The Stroop Test (Stroop, 1935) is usually used to evaluate selective attention. This study investigated whether children with ADHD could exhibit modified performance in the Stroop Test. Using a computerized version of this test (Capovilla, Montiel, Macedo, & Charin, 2005), the study compared the reaction times (RTs) of 62 Brazilian children, between 8 and 12 years of age, 31 of whom were diagnosed with ADHD and sent to psychiatric clinics, and 31 without ADHD studying in regular schools. All children with ADHD satisfied the criteria of the DSM-IV-TR and were evaluated with the Conners Abbreviated Questionnaire (Goyette, Conners, & Ulrich, 1978), completed by parents and teachers. The results revealed that children with ADHD exhibit greater interference in RT than children without ADHD. This corroborated the hypothesis that children with ADHD exhibit a deficit in selective attention, consisting in augmented RTs, as measured by the Computerized Stroop Test. La investigación ha mostrado la función anormal del córtex prefrontal en el trastorno de déficit de atención con hiperactividad (TDAH). Este córtex está implicado en el control de las funciones ejecutivas relacionadas con la planificación y ejecución de estrategias orientadas a objetivos, la memoria de trabajo, las inhibiciones, la flexibilidad cognitiva y la atención selectiva. La atención selectiva implica centrarse en el estímulo diana, ignorando las distracciones que compiten para la atención. Normalmente se emplea la prueba Stroop (Stroop, 1935) para evaluar la atención selectiva. En este estudio se investigó si le ejecución en la prueba Stroop de niños con TDAH podría sufrir modificaciones. Empleando una versión informatizada de esta prueba (Capovilla, Montiel, Macedo y Charin, 2005), el estudio comparó los tiempos de reacción (TR) de 62 niños brasileños, con edades entre los 8 y los 12 años, de los cuales 31 fueron diagnosticados de TDAH y estaban en clínicas psiquiátricas, y 31 sin TDAH que estudiaban en colegios normales. Todos los niños con TDAH cumplían los criterios del DSM-IV-TR y fueron evaluados con el Cuestionario Abreviado de Conners (Goyette, Conners y Ulrich, 1978), cumplimentado por padres y profesores. Los resultados revelaron que los niños con TDAH mostraron más interferencia en TR que los niños sin TDAH. Esto corroboró la hipótesis de que los niños con TDAH exhiben un déficit en la atención selectiva, que consiste en TR aumentados, tal y como se miden con la Prueba Stroop Informatizada.
Alignment of non-overlapping sequences

This paper shows how two image sequences that have no spatial overlap between their fields of view can be aligned both in time and in space. Such alignment is possible when the two cameras are attached closely together and are moved jointly in space. The common motion induces "similar" changes over time within the two sequences. This correlated temporal behavior is used to recover the spatial and temporal transformations between the two sequences. The requirement of "coherent appearance" in standard image alignment techniques is therefore replaced by "coherent temporal behavior", which is often easier to satisfy. This approach to alignment can be used not only for aligning nan-overlapping sequences, but also for handling other cases that are inherently difficult for standard image alignment techniques. We demonstrate applications of this approach to three real-world problems: (i) alignment of non-overlapping sequences for generating wide-screen movies, (ii) alignment of images (sequences) obtained at significantly different zooms, for surveillance applications, and (iii) multi-sensor image alignment for multi-sensor fusion.
Photographic Measurements in 301 Cases of Liposuction and Abdominoplasty Reveal Fat Reduction without Redistribution

Background: There are no published studies of liposuction or abdominoplasty in a large number of patients using measurements of body dimensions. In the absence of rigorous data, some investigators have proposed that fat returns after liposuction. Methods: A prospective study was undertaken among predominantly nonobese consecutive patients undergoing 301 liposuction and abdominoplasty procedures meeting the study criteria (inclusion rate, 70.7 percent). Lower body dimensions were measured using standardized photographs taken before and at least 3 months after surgery. Upper body measurements were compared between women who underwent simultaneous cosmetic breast surgery (n = 67) and a group of women who had breast surgery alone (n = 78) to investigate the possibility of fat redistribution. Results: The average weight change was a loss of 2.2 lbs after lower body liposuction (p < 0.01) and 4.6 lbs when combined with abdominoplasty (p < 0.001). Liposuction significantly reduced abdominal, thigh, knee, and arm width (p < 0.001). Midabdominal and hip width were more effectively reduced by lipoabdominoplasty than liposuction alone (p < 0.001). There was no difference in upper body measurements when comparing patients who had simultaneous liposuction and/or abdominoplasty with patients who had cosmetic breast surgery alone. Measurements in patients with at least 1 year of follow-up (n = 46) showed no evidence of fat reaccumulation. Conclusions: Both liposuction and abdominoplasty are valid techniques for long-term fat reduction and improvement of body proportions. There is no evidence of fat regrowth. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
Systems for Detecting Advanced Persistent Threats: A Development Roadmap Using Intelligent Data Analysis

Cyber-attacks against companies and governments are increasing in complexity, persistence and numbers. Common intrusion detection methods lack the ability to detect such - what are commonly termed - advanced persistent threats. A new approach is needed that takes the stepwise characteristics of this type of threats into account and links analysis methods to attack features. This paper takes up this challenge. First, an analysis framework is proposed to relate complex attack attributes to detection and business aspects. Second, the framework is used to define a development roadmap for designing advanced intrusion detection systems, such systems can analyze network traffic and client data at multiple network locations using both signature and anomaly detection methods derived from the intelligent data analysis field. Third, a test case is provided showing the potential power of the proposed development roadmap.
Valproic acid attenuates the multiple-organ dysfunction in a rat model of septic shock.

BACKGROUND Valproic acid (VPA) improves early survival and organ function in a highly lethal poly-trauma and hemorrhagic shock model or other severe insults. We assessed whether VPA could improve organ function in a rat model of septic shock and illustrated the possible mechanisms. METHODS Forty Sprague-Dawley rats were randomly assigned to four groups (n = 10): control group, VPA group, LPS group, and LPS + VPA group. Lipopolysaccharide (LPS) (10 mg/kg) was injected intravenously to replicate the experimental model of septic shock. Rats were treated with VPA (300 mg/kg, i.v.) or saline. Six hours after LPS injection, blood was sampled for gas analysis, measurement of serum alanine aminotransferase, aspartate aminotransferase, urine nitrogen, creatinine and tumor necrosis factor-alpha. Lung, liver and kidney were collected for histopathological assessment. In addition, myeloperoxidase activity and tumor necrosis factor-a in pulmonary tissue were measured. Acetylation of histone H3 in lung was also evaluated by Western blotting. RESULTS LPS resulted in a significant decrease in PaO2, which was increased by VPA administration followed LPS injection. In addition, LPS also induced an increase in the serum levels of alanine aminotransferase, aspartate aminotransferase, urine nitrogen, creatinine, and tumor necrosis factor-alpha. However, these increases were attenuated in the LPS + VPA group. The lungs, liver and kidneys from the LPS group were significantly damaged compared with the control group. However, the damage was attenuated in the LPS + VPA group. Myeloperoxidase activity and tumor necrosis factor-alpha levels in pulmonary tissue increased significantly in the LPS group compared with the control group. These increases were significantly inhibited in the LPS + VPA group. Acetylation of histone H3 in lung tissue in the LPS group was inhibited compared with the control. However, the level of acetylation of histone H3 in the LPS + VPA group was markedly elevated in contrast to the LPS group. CONCLUSIONS Treatment with VPA can attenuate multiple organ damage caused by LPS induced septic shock. Our data also suggest that the beneficial effects are in part due to the decrease in inflammatory cytokines and restoration of normal acetylation homeostasis.
SIFTpack: A Compact Representation for Efficient SIFT Matching

Computing distances between large sets of SIFT descriptors is a basic step in numerous algorithms in computer vision. When the number of descriptors is large, as is often the case, computing these distances can be extremely time consuming. In this paper we propose the SIFT pack: a compact way of storing SIFT descriptors, which enables significantly faster calculations between sets of SIFTs than the current solutions. SIFT pack can be used to represent SIFTs densely extracted from a single image or sparsely from multiple different images. We show that the SIFT pack representation saves both storage space and run time, for both finding nearest neighbors and for computing all distances between all descriptors. The usefulness of SIFT pack is also demonstrated as an alternative implementation for K-means dictionaries of visual words.
The effects of vasoactive agents, platelet agonists and anticoagulation on thrombelastography

Background: Platelet activation is a critical step in primary hemostasis and clot formation. We tested a hypothesis that platelet stimulating effects of vasoactive agents or platelet agonists could be shown using thrombelastography (TEG®) as faster onset or increased clot strength. We further examined if TEG® could be modified to evaluate activated platelets as a reversal of anticoagulation in the presence of partial thrombin inhibition.
Malignant melanoma metastasising to a basal cell carcinoma

Melanocytes may colonize a range of skin tumours and, in particular, basal cell carcinomas and seborrhoeic keratoses. Recently, melanocytes have been shown to infiltrate an eccrine porocarcinoma both at the primary site and also within lymph node metastatic deposits. Colonization of tumours by malignant melanocytes however, has not been previously reported. In this report we describe a case of malignant melanoma metastasising to a basal cell carcinoma. Melanoma commonly metastasises to skin in over 75% of fatal cases but, as far as we are aware, this is the first report of metastatic melanoma presenting as spread to a second primary cutaneous tumour.
Small Feedback Vertex Sets in Planar Digraphs

Let $G$ be a directed planar graph on $n$ vertices, with no directed cycle of length less than $g\ge 4$. We prove that $G$ contains a set $X$ of vertices such that $G-X$ has no directed cycle, and $|X|\le \tfrac{5n-5}9$ if $g=4$, $|X|\le \tfrac{2n-5}4$ if $g=5$, and $|X|\le \tfrac{2n-6}{g}$ if $g\ge 6$. This improves recent results of Golowich and Rolnick.
Electrophysiological Correlates of Category Induction in Children and Adults

Category induction involves abstraction of features common to two or more stimuli. Event-related potentials (ERPs) during induction and non-induction tasks were recorded for 12 children and 12 adults. We found that (1) ERP waves, except P2 amplitude, decreased significantly with age, (2) Compared to non-induction tasks, induction tasks elicited larger fronto-central N2 components in both age groups, (3) The amplitude of the late positive component was significantly greater in the induction condition than in the non-induction condition, and (4) The difference wave suggested that category induction was mainly located in the left hemisphere in children but was not lateralized in adults.
High Energy, High Average Power, Picosecond Laser Systems To Drive Few-cycle Opcpa

The invention of chirped-pulse amplification (CPA) in 1985 led to a tremendous increase in obtainable laser pulse peak intensities. Since then, several table-top, Ti:sapphire-based CPA systems exceeding the 100 TW-level with more than 10 W average power have been developed and several systems are now commercially available. Over the last decade, the complementary technology of optical parametric chirped-pulse amplification (OPCPA) has improved in its performance to a competitive level. OPCPA allows direct amplification of an almost-octave spanning bandwidth supporting few-cycle pulse durations at center wavelengths ranging from the visible to the mid-IR. The current record in peak power from a table-top OPCPA is 16 TW and the current record average power is 22 W. High energy, few-cycle pulses with stabilized carrierenvelope phase (CEP) are desired for applications such as high-harmonic generation (HHG) enabling attoscience and the generation keV-photon bursts. This dissertation conceptually, numerically and experimentally describes essential aspects of few-cycle OPCPA, and the associated pump beam generation. The main part of the conducted research was directed towards the few-cycle OPCPA facility developed in the Laser Plasma Laboratory at CREOL (University of Central Florida, USA) termed HERACLES. This facility was designed to generate few-cycle pulses in the visible with mJ-level pulse energy, W-level average power and more than 100 GW peak power. Major parts of the implementation of the HERACLES facility are presented. The pump generation beam of the HERACLES system has been improved in terms of pulse energy, average power and stability over the last years. It is based on diode-pumped, solid-state amplifiers with picosecond duration and experimental investigations are presented in detail. A
Exploring the design space of future CMPs

We study the space of chip multiprocessor (CMP) organizations. We compare the area and performance trade-offs for CMP implementations to determine how many processing cores future server CMPs should have, whether the cores should have in-order or out-of-order issues, and how big the per-processor on-chip caches should be. We find that, contrary to some conventional wisdom, out-of-order processing cores will maximize job throughput on future CMPs. As technology shrinks, limited off-chip bandwidth will begin to curtail the number of cores that can be effective on a single die. Current projections show that the transistor/signal pin ratio will increase by a factor of 45 between 180 and 35 nanometer technologies. That disparity will force increases in per-processor cache capacities as technology shrinks, from 128KB at 100nm, to 256KB at 70nm, and to 1MB at 50 and 35nm, reducing the number of cores that would otherwise be possible.
Serum Lipid Profile Constituents as Markers of Cardiovascular Morbidity in Patients on Chronic Hemodialysis

We designed the present case-control study in order to examine the validity of apolipoprotein (apo) A-I, B, apoB/apoA-I ratio and Lp(a) as alternative markers of cardiovascular morbidity in end-stage renal disease (ESRD) patients undergoing chronic hemodialysis (HD). Twenty-five HD patients (18 males, mean age 63, range 52–69 years) comprised the group with prevalent cardiovascular disease (CVD) and 50 HD patients (35 males, mean age 62, range 40–77 years) with non evident cardiovascular disease history constituted the second study group. Patients with CVD had significantly higher concentrations of serum apoB, apoB/apoA-I ratio and Lp(a), and lower levels of apoA-I compared to patients without incident CVD. All three parameters studied were correlated with cardiovascular morbidity, i.e. apoA-I negatively and apoB and apoB/apoA-I ratio positively (r = −0.6, P < 0.05; r = 0.659, P < 0.01; and r = 0.614, P < 0.01, respectively). Furthermore, logCRP exhibited as well a significant positive correlation with cardiovascular morbidity (r = 0.704, P < 0.001), not this being the case for Lp(a) which was not found to exhibit such a correlation (r = 0.05, P = NS). Among them, apoB and apoB/apoA-I ratio exhibited the characteristics most coherent to CVD. The age- and sex-adjusted OR for the presence of CVD was 2.3 and 2.0, respectively, which remained independent of any confounding effect of inflammation. In conclusion, serum apoB levels and apoB/apoA-I ratio exhibit characteristics of credible independent markers of in HD patients.