Miracle-dz/UniFAR-FTUs huggingface dataset:
Dynamics of coordination within elite rowing crews: evidence from force pattern analysis

For a rowing crew to be successful, the movements of the rowers need to be well coordinated. Because rowers show individual force patterns, they have to adapt their movements when rowing as a crew. In this exploratory study, these hypothesized changes in movement pattern were examined. The force graphs of six elite coxless fours crews were recorded over 11 training runs using strain gauges attached to the oars. A detailed force analysis showed that form differences, but not area differences, between force patterns decreased when force output increased as a result of two different processes. First, increasing force output reduced form differences instantaneously by reducing the individual variation in force patterns. Secondly, the kinaesthetic perception of form differences is easier than that of area differences. This better perception facilitates the adaptation of movement patterns, especially when force output is high.
Identification of Human Sperm Peptide Sequence Involved in Egg Binding for Immunocontraception1

Abstract Development of a vaccine based on sperm antigens represents a promising approach to contraception. The sperm-zona pellucida (ZP) interaction constitutes the most important event in the fertilization process, and the molecular sequences involved at this site may provide the most attractive candidates for immunocontraception. In the present study, using the phase peptide display technique, a novel dodecamer sequence, designated as YLP12, was identified that is involved in sperm-ZP recognition/binding. The synthetic 12-mer peptide based on this sequence and its monovalent Fab′ antibodies specifically and significantly (P < 0.05) inhibited human sperm-ZP binding. In Western blot and immunoprecipitation procedures, the YLP12 peptide recognized the ZP3 component of solubilized human ZP proteins. In the Western blot procedure involving 10 different human tissue extracts, the anti-YLP12 Fab′ antibodies recognized a protein band of ∼72 ± 2 kDa only in the testis lane. The peptide sequence was localized on the acrosomal region of the human sperm cell. These findings indicate that the novel testis-specific 12-mer YLP12 that is present in the acrosomal region and is involved in human sperm-ZP interaction may find applications in contraceptive vaccine development, as well as in diagnosis and treatment of male infertility mediated through sperm dysfunction.
DSM-5 Diagnostic Criteria for Autism Spectrum Disorder With Implications for School Psychologists

Changes to the diagnosis of autism spectrum disorder (ASD) within the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5; American Psychiatric Association, 2013) have important implications for school psychologists responsible for evaluating children with ASD, interpreting results to caregivers, and informing policy makers of needed revisions to eligibility criteria based on empirical understanding. The primary purpose of this review is to describe changes to the DSM-5 and the empirical evidence behind the modifications. A secondary goal is to describe implications for best practices in school evaluations for ASD. Given the concerns about the DSM-5 expressed by caregivers and individuals with ASD during the revision process, school psychologists who are aware of the rationale for and implications of the changes will be better positioned to assist local policy makers regarding diagnostic evaluations for ASD and address parental concerns regarding the evaluation process and service implications for their child.
THE EFFECT OF EXERCISE ON DIABETIC CONTROL AND HEMOGLOBIN A1 (HbA1) IN CHILDREN

Abstract. Dahl‐Jørgensen, K. , Meen, H. D. , Hanssen, Kr. F. and Aagem, O. (Department of Paediatrics and Department of Internal Medicine, Aker Hospital and the Norwegian College of Physical Education and Sports, Oslo, Norway). Acta Paediatr Scand, Suppl. 283: 53, 1980. —14 children with juvenile diabetes mellitus (mean age 11 years, mean diabetes duration 5 years) were enrolled in a one‐hour twice weekly supervised exercise program for 5 months. A group of 8 diabetic children of same age and diabetic duration served as control group. Maximum oxygen uptake was within normal range for all children. With this exercise program the maximum oxygen uptake of the training group did not change significantly compared with the control group. The physicians rating of degree of the metabolic control based on blood‐glucose measurements and urinary glucose excretion did not change in any of the groups. The insulin dosage per kilo body weight remained unchanged in both groups. In the training group the HbA, values decreased during the exercise period from 15.1±2.2 (mean HbA1%±1 S.D.) to 13.8±1.9 (2p<0.001). In the control group the HbA1 values did not change significantly (13.4± 1.9 to 12.9± 1.6; 2p=0.20). In a co‐study the effect of freezing and storage of hemolysates, resulting in increased levels of HbA1, was demonstrated.
Pipelining broadcasts on heterogeneous platforms

Summary form only given. We consider the communications involved by the execution of a complex application, deployed on a heterogeneous platform. Such applications extensively use macro-communication schemes, for example to broadcast data items. Rather than aiming at minimizing the execution time of a single broadcast, we focus on the steady-state operation. We assume that there is a large number of messages to be broadcast in pipeline fashion, or a large message that can be split into several packets, and we aim at maximizing the throughput, i.e. the (rational) number of messages which can be broadcast every time-step. We target heterogeneous platforms, modeled by a graph where resources have different communication speeds. Achieving the best throughput may well require that the target platform is used in totality: we show that neither spanning trees nor DAGs are as powerful as general graphs. We show how to compute the best throughput using linear programming, and how to exhibit a periodic schedule, first when restricting to a DAG, and then when using a general graph. The polynomial compactness of the description comes from the decomposition of the schedule into several broadcast trees that are used concurrently to reach the best throughput. It is important to point out that a concrete scheduling algorithm based upon the steady-state operation is asymptotically optimal, in the class of all possible schedules (not only periodic solutions).
How do health care providers perceive technologies for monitoring older adults?

Monitoring and assistive technologies for the older adults, by sensing and recording activities and status, provide an objective record of a patient’s functioning within natural environments. Yet the data derived from these technologies do not directly address the clinical aims of health care providers. We conducted focus groups with health care providers who work with older adults to elicit their perspectives on monitoring technologies. Identified themes centered around the benefits and risks of technologies, patient needs, the clinical utility of information, and specific monitoring domains that might improve the health care of older adults. Providers highlighted the primary importance of involving families and caregivers, and of sustaining human interactions. They explored the difficulties with how to use information for clinical ends, and challenged the notion that more objective information would automatically improve their heath care. Designers, developers, and researchers might improve the utility and uptake of health-related technologies for older adults and their families by eliciting the viewpoints of clinical providers.
Joint defragmentation of optical spectrum and IT resources in elastic optical datacenter interconnections

With its agile spectrum management in the optical layer, the flexible-grid elastic optical network can become a promising physical infrastructure to efficiently support the highly dynamic traffic in future datacenter interconnections (DCIs). While the resulting elastic optical DCIs (EO-DCIs) need to serve requests that not only require bandwidth resources on fiber links but also require multidimensional IT resources in the DCs, multidimensional resource fragmentation can occur during dynamic network operations and deteriorate the network performance. To address this issue, this paper investigates the problem of joint defragmentation (DF) for the spectrum and IT resources in EO-DCIs. Specifically, we reoptimize the allocations of multidimensional resources jointly with complexity-controlled network reconfigurations. For the DFoperation, we first study the request selection process and propose a joint selection strategy that can perform the spectrum- and IT-oriented selections adaptively according to the network status. Then, we formulate a mixed integer linear programming model and design several heuristics to tackle the problem of network reconfiguration in the joint DF. The proposed algorithms are evaluated with extensive simulations. Simulation results demonstrate that the proposed joint DF algorithms can significantly reduce the blocking probability in EO-DCIs by consolidating the spectrum and IT resource usages effectively.
Human identification from body shape

We investigate the utility of static anthropometric distances as a biometric for human identification. The 3D landmark data from the CAESAR database is used to form a simple biometric consisting of distances between fixed rigidly connected body locations. This biometric is overt, and invariant to view and body posture. We use this to quantify the asymmetry of human bodies, and to characterize the interpersonal and intrapersonal distance distributions. The former is computed directly and the latter by adding zero-mean gaussian noise to the landmark points. This simulation framework is applicable to arbitrary shape based biometrics. We use gross body proportions information to model a computer vision recognition system.
Unsupervised iterative detection of land mines in highly cluttered environments

An unsupervised iterative scheme is proposed for land mine detection in heavily cluttered scenes. This scheme is based on iterating hybrid multispectral filters that consist of a decorrelating linear transform coupled with a nonlinear morphological detector. Detections extracted from the first pass are used to improve results in subsequent iterations. The procedure stops after a predetermined number of iterations. The proposed scheme addresses several weaknesses associated with previous adaptations of morphological approaches to land mine detection. Improvement in detection performance, robustness with respect to clutter inhomogeneities, a completely unsupervised operation, and computational efficiency are the main highlights of the method. Experimental results reveal excellent performance.
The fla gene cluster is involved in the biogenesis of flagella in Halobacterium salinarum

In this study, a flagella‐related protein gene cluster is described for Halobacterium salinarum. The fla gene cluster is located upstream of the flagellin genes flgB1–3 and oriented in the opposite direction. It consists of nine open reading frames (ORFs): htpIX, a member of the halobacterial transducer protein gene family, and the genes flaD–K. The genes flaD, E, G, H, I and J share high homologies with genes from other Archaea. Interestingly, flaK shows similarities to bacterial genes involved in the regulation of flagellar synthesis. The ORFs of flaH, flaI and flaK contain sequences coding for nucleotide binding sites. Furthermore, flaI contains a motif called the bacterial type II secretion protein E signature, indicating a functional relation to members of the bacterial pili type IV–type II secretion protein superfamily. Reverse transcription–polymerase chain reaction (RT–PCR) analysis revealed that the genes flaE to flaK are transcribed into one polycistronic message. In frame deletion mutants of flaI were generated by gene replacement. The deletion strain lacks motility and belongs to the fla– mutant class, indicating that it is deficient in flagellar biogenesis. The overall amount of flagellin protein in ΔflaI cells is reduced, although transcription of the flagellin genes is unaffected. Therefore, the flaI gene product is involved in the biosynthesis, transport or assembly of flagella in H. salinarum.
On the diurnal cycle and susceptibility to aerosol concentration in a stratocumulus‐topped mixed layer

Mixed‐layer theory is used to study the diurnal cycle of the stratocumulus‐topped boundary layer and its susceptibility to perturbations in atmospheric aerosol concentration. Our results show that the diurnal evolution of cloud thickness is sensitive to the entrainment effisciency. For high entrainment efficiencies, the cloud base tends to descend at a faster rate than the cloud top; this difference in descent rates leads to cloud thickening during the daytime, which is inconsistent with observations. For low entrainment efficiencies, variations in cloud‐top height dominate in the cloud‐thickness evolution, while cloud‐base height remains almost constant; this behaviour is in better agreement with available data. We explain these effects through a consideration of the equilibrium state of cloud boundaries and their adjustment time‐scales. Liquid‐water path and cloud albedo are both sensitive to the entrainment efficiency; still, the susceptibility of cloud albedo to droplet number density dominates the entrainment effects. This result has significant implications for climate‐sensitivity studies: it suggests that estimates of aerosol indirect effects from stratocumulus clouds will not be particularly sensitive to the way entrainment is represented in large‐scale models. Copyright © 2005 Royal Meteorological Society
Character-level Convolutional Networks for Text Classification

This article offers an empirical exploration on the use of character-level convolutional networks (ConvNets) for text classification. We constructed several large-scale datasets to show that character-level convolutional networks could achieve state-of-the-art or competitive results. Comparisons are offered against traditional models such as bag of words, n-grams and their TFIDF variants, and deep learning models such as word-based ConvNets and recurrent neural networks.
THE GENOTYPE EFFECT ON THE RATIO OF WET GLUTEN CONTENT TO TOTAL WHEAT GRAIN PROTEIN

Gluten proteins are primarily responsible for the end-use wheat quality and quite a number of methods for gluten quality evaluation was suggested and applied. The aim of the work presented here was to examine the genotype effect on the ratio of wet gluten to total protein content (WG/P), as measure of wet gluten production per protein unit. Ten winter wheat cultivars of Agricultural Institute Osijek were included in this study. Signifi cant (P 90), known as improvers, had WG/P ratio between 2.3 and 2.4. Signifi cant (P<0.05) negative correlation (r=-0.622) was determined between GI and WG/P ratio.
Up-regulated miR155 Reverses the Epithelial-mesenchymal Transition Induced by EGF and Increases Chemo-sensitivity to Cisplatin in Human Caski Cervical Cancer Cells

The epithelial-mesenchymal transition (EMT) induced by EGF promotes cervical cancer progression; however, the mechanisms underlying the EGF-induced EMT remain unclear. In this study, we reported that miR155 overexpression suppressed EGF-induced EMT, decreased migration/invasion capacities, inhibited cell proliferation and increased the chemo-sensitivity to DDP in human Caski cervical cancer cells. Further, the overexpression of miR155 increased TP53 expression but reduced SMAD2, and CCND1 expression levels. These data suggest that miR155 negatively regulates EGF-induced EMT. We conclude that miR155 does not act as an oncogene but as a tumour suppressor in Caski cells.
Identification of DNA-Damage DNA-Binding Protein 1 as a Conditional Essential Factor for Cytomegalovirus Replication in Interferon-γ-Stimulated Cells

The mouse cytomegaloviral (MCMV) protein pM27 represents an indispensable factor for viral fitness in vivo selectively, antagonizing signal transducer and activator of transcription 2 (STAT2)-mediated interferon signal transduction. We wished to explore by which molecular mechanism pM27 accomplishes this effect. We demonstrate that pM27 is essential and sufficient to curtail the protein half-life of STAT2 molecules. Pharmacologic inhibition of the proteasome restored STAT2 amounts, leading to poly-ubiquitin-conjugated STAT2 forms. PM27 was found in complexes with an essential host ubiquitin ligase complex adaptor protein, DNA-damage DNA-binding protein (DDB) 1. Truncation mutants of pM27 showed a strict correlation between DDB1 interaction and their ability to degrade STAT2. SiRNA-mediated knock-down of DDB1 restored STAT2 in the presence of pM27 and strongly impaired viral replication in interferon conditioned cells, thus phenocopying the growth attenuation of M27-deficient virus. In a constructive process, pM27 recruits DDB1 to exploit ubiquitin ligase complexes catalyzing the obstruction of the STAT2-dependent antiviral state of cells to permit viral replication.
Combining Instance and Feature Neighbors for Efficient Multi-label Classification

Multi-label classification problems occur naturally in different domains. For example, within text categorization the goal is to predict a set of topics for a document, and within image scene classification the goal is to assign labels to different objects in an image. In this work we propose a combination of two variations of k nearest neighborhoods (kNN) where the first neighborhood is computed instance (or row) based and the second neighborhood is feature (or column) based. Instance based kNN is inspired by user-based collaborative filtering, while feature kNN is inspired by item-based collaborative filtering. Finally we apply a linear combination of instance and feature neighbors scores and apply a single threshold to predict the set of labels. Experiments on various multi-label datasets show that our algorithm outperforms other state-of-the-art methods such as ML-kNN, IBLR and Binary Relevance with SVM, on different evaluation metrics. Finally our algorithm uses an inverted index during neighborhood search and scales to extreme datasets that have millions of instances, features and labels.
Occupation and pancreatic cancer in Spain: a case-control study based on job titles. PANKRAS II Study Group.

BACKGROUND Occupational exposures may increase the risk of exocrine pancreatic cancer. This study aimed to identify occupations that in Spain may be associated with such risk. METHODS Incident cases of pancreatic cancer and hospital controls were prospectively identified and interviewed during their hospital stay. Occupational history was obtained by direct interview with the patient and was available for 164 (89%) of 185 pancreatic cancer cases and for 238 (90%) of 264 controls. Occupations were coded according to the Spanish version of the International Standard Classification of Occupations 1988. RESULTS A significant increased odds ratio (OR) was observed in men for 'physical, chemistry and engineering science technicians'. Elevated risks were also found for 'metal moulders, sheet-metal workers, structural metal workers, welders and related workers', 'painters and varnishers' and 'machinery mechanics and fitters'. 'Agricultural workers' did not present an increased risk for pancreas cancer in men. In women, however, high OR were observed for 'agricultural workers' and for 'textile and garment workers'. Most associations remained unchanged after considering long duration of the exposure and the period 5-15 years before diagnosis. CONCLUSIONS Few occupations were at increased risk for pancreatic cancer, and the associations observed are in accordance with previous studies. The increases in risk observed for women in agricultural and textile jobs, and for men in the manufacture of dyes and pigments may deserve further attention.
Event-related Brain Potentials Elicited by Morphological, Homographic, Orthographic, and Semantic Priming

The morphological structure of words, in terms of their stem morphemes and affixes, could influence word access and representation in lexical memory. Three experiments were carried out to explore the attributes of event-related potentials evoked by different types of priming. Morphological priming, with pairs of words related by their stem (hijo/hija [son/ daughter]), produced a sustained attenuation (and even a tendency to positivity) of the N400 shown by unrelated words across the three experiments. Homographic priming (Experiment 1), using pairs of words with a superficially similar stem, but without morphological or semantic relation (foco/foca [floodlight/seal]), produced an initial attenuation similar to the morphological pairs, but which rapidly tended to form a delayed N400, due to the impossibility of integration. However, orthographic priming (rasa/rana [flat/frog]) in Experiment 2 does not produce attenuation of the N400 but an effect similar to that of unrelated pairs. Experiment 3 shows that synonyms advance more slowly than morphological pairs to meaning coherence, but finally produce a more positive peak around 600 msec.
Dependence of secondary crater characteristics on downrange distance: High‐resolution morphometry and simulations

On average, secondary impact craters are expected to deepen and become more symmetric as impact velocity (vi) increases with downrange distance (L). We have used high‐resolution topography (1–2 m/pixel) to characterize the morphometry of secondary craters as a function of L for several well‐preserved primary craters on Mars. The secondaries in this study (N = 2644) span a range of diameters (25 m ≤D≤400 m) and estimated impact velocities (0.4 km/s ≤vi≤2 km/s). The range of diameter‐normalized rim‐to‐floor depth (d/D) broadens and reaches a ceiling of d/D≈0.22 at L≈280 km (vi= 1–1.2 km/s), whereas average rim height shows little dependence on vi for the largest craters (h/D≈0.02, D > 60 m). Populations of secondaries that express the following morphometric asymmetries are confined to regions of differing radial extent: planform elongations (L< 110–160 km), taller downrange rims (L < 280 km), and cavities that are deeper uprange (L< 450–500 km). Populations of secondaries with lopsided ejecta were found to extend to at least L ∼ 700 km. Impact hydrocode simulations with iSALE‐2D for strong, intact projectile and target materials predict a ceiling for d/D versus L whose trend is consistent with our measurements. This study illuminates the morphometric transition from subsonic to hypervelocity cratering and describes the initial state of secondary crater populations. This has applications to understanding the chronology of planetary surfaces and the long‐term evolution of small crater populations.