Miracle-dz/UniFAR-FTUs huggingface dataset:
Mathematical literacy examination items and student errors: An analysis of English Second Language students’ responses

Mathematical literacy is a real-world practical attribute yet students write a high-stakes examination in order to pass the subject Mathematical Literacy in the National Certificates (Vocational) (NC(V)). In these examinations, all sources of information are contextualised in language. It can be effortful for English second language students to decode text. The deliberate processing that is required saturates working memory and prevents these students from optimally engaging in problem solving. In this study, 15 items from an NC(V) Level 4 Mathematical Literacy examination are selected, as well as 15 student responses to each of these questions. From these responses, those which are incorrect are analysed to determine whether the error is due to insufficient mathematical literacy or a lack of English language proficiency. These results are used as an indication as to whether the examination is fair and valid for this group of students.
Effect of different cleaning regimens on the adhesion of resin to saliva-contaminated ceramics.

PURPOSE The aim of this study was to evaluate the influence of different cleaning regimens on the microshear bond strength (μSBS) of three different all-ceramic surfaces after saliva contamination. MATERIAL AND METHODS Cubic ceramic specimens (3 × 3 × 3 mm(3) ) were prepared from three types of ceramics: zirconium dioxide (Z), leucite-reinforced glass ceramic (E), lithium disilicate glass ceramic (EX; n = 12/subgroup). A total of 144 composite resin cylinders (diameter: 1 mm, height: 3 mm) were prepared. Three human-saliva-contaminated surfaces of ceramic specimens were cleaned with either water spray (WS), with 0.5% sodium hypochlorite solution (HC), or with a cleaning paste (CP). Control surface (C) was not contaminated or cleaned. Composite cylinders were bonded to each surface with a resin luting cement. All specimens were stored at 37°C in deionized water until fracture testing. μSBS tests were performed in a universal testing machine (0.5 mm/min), and the results (MPa ± SD) were statistically analyzed (two-way ANOVA, Bonferroni a = 0.05). Fractured surfaces were analyzed to identify the failure types using an optical microscope at 50× magnification. Two representative specimens from all groups were examined with scanning electron microscopy. RESULTS μSBS test results were significantly affected by the saliva cleaning regimens (p = 0.01) and the ceramic types (p = 0.03). The interaction terms between the ceramic type and saliva cleaning regimen were also significant (p < 0.05). There were no significant differences among the μSBS values (MPa ± SD) for the Z group (C = 17.5 ± 8.8; WS = 16.0 ± 4.9; HC = 17.6 ± 5.8; CP = 16.6 ± 7.5; p > 0.05). In the EX group, C resulted in significantly higher μSBS values (32.6 ± 7.4) than CP (17.4 ± 8.9), WS (15.6 ± 7.3), and HC (14.3 ± 4.5) (p < 0.05); however, C (20.4 ± 7.1) and HC (19.2 ± 7.5) showed higher μSBS values than CP (13.8 ± 4.8) and WS (10.9 ± 5.7) in the E group. Some cohesive failures within the luting resin were observed in the E and EX groups, whereas only adhesive failures were seen in zirconia groups for all surface treatments. CONCLUSIONS Different ceramic surface cleaning regimens after saliva contamination of the zirconium dioxide revealed μSBS similar to the control group, whereas all surface cleaning regimens tested significantly decreased the bond strength values in the lithium disilicate glass ceramic. The leucite-reinforced glass-ceramic group benefited from 0.5% sodium hypochlorite solution cleaning with increased bond strengths. CLINICAL SIGNIFICANCE Adhesive cementation of zirconia presents a clinically challenging protocol, and the cementation surface contamination of the zirconia restorations and the inadequate removal of the contaminants increase the risk of failure, as for all ceramic types. This study demonstrated that surface cleaning regimens should be applied according to different ceramic properties.
Cultural map of Finland 2007: analysing cultural differences using multiple correspondence analysis

This paper explores the patterns of cultural consumption in Finland using data collected in 2007 from a randomly selected sample of 3,000 persons. This is an explanatory study employing Multiple Correspondence Analysis as a method to map the cultural consumption patterns in Finland. The paper refers to a number of previous studies addressing the same issue in Denmark and particularly the UK in an attempt to place the results within a comparison framework. The main argument of this paper is not simply that within socio-economic groups there is a preference for similar culture, but that cultural preferences follow a structure over different domains that can be detected without reference to socio-economic factors. As a result of the analysis, two dimensions of the MCA solution are found, which represent differentiations between high engagement in culture versus disengagement and contemporary versus traditional forms of culture. These dimensions are very similar to the dimensions found in the UK, even if the placement of individual cultural activities varies somewhat. The applicability of the Bourdieusian approach to cultural differences between classes, as well as recent critical developments of the theory of distinction, will be discussed in light of the results.
Rationally Repurposing Ruxolitinib (Jakafi®) as a Solid Tumor Therapeutic

We determined whether the approved myelofibrosis drug ruxolitinib (Jakafi®), an inhibitor of Janus kinases 1/2 (JAK1 and JAK2), could be repurposed as an anti-cancer agent for solid tumors. Ruxolitinib synergistically interacted with dual ERBB1/2/4 inhibitors to kill breast as well as lung, ovarian and brain cancer cells. Knock down of JAK1/2 or of ERBB1/2/3/4 recapitulated on-target drug effects. The combination of (ruxolitinib + ERBB1/2/4 inhibitor) rapidly inactivated AKT, mTORC1, mTORC2, STAT3, and STAT5, and activated eIF2α. In parallel, the drug combination reduced expression of MCL-1, BCL-XL, HSP90, HSP70, and GRP78, and increased expression of Beclin1. Activated forms of STAT3, AKT, or mTOR prevented the drug-induced decline in BCL-XL, MCL-1, HSP90, and HSP70 levels. Over-expression of chaperones maintained AKT/mTOR activity in the presence of drugs and protected tumor cells from the drug combination. Expression of dominant negative eIF2α S51A prevented the increase in Beclin1 expression and protected tumor cells from the drug combination. Loss of mTOR activity was associated with increased ATG13 S318 phosphorylation and with autophagosome formation. Autophagosomes initially co-localized with mitochondria and subsequently with lysosomes. Knock down of Beclin1 suppressed: drug-induced mitophagy; the activation of the toxic BH3 domain proteins BAX and BAK; and tumor cell killing. Knock down of apoptosis-inducing factor (AIF) protected tumor cells from the drug combination, whereas blockade of caspase 9 signaling did not. The drug combination released AIF into the cytosol and increased nuclear AIF: eIF3A co-localization. A 4-day transient exposure of orthotopic tumors to (ruxolitinib + afatinib) profoundly reduced mammary tumor growth over the following 35 days. Re-grown tumors exhibited high levels of BAD S112 phosphorylation and activation of ERK1/2 and NFκB. Our data demonstrate that mitophagy is an essential component of (ruxolitinib + ERBB inhibitor) lethality and that this drug combination should be explored in a phase I trial in solid tumor patients.
The importance of long-range dependence of VBR video traffic in ATM traffic engineering: myths and realities

There has been a growing concern about the potential impact of long-term correlations (second-order statistic) in variable-bit-rate (VBR) video traffic on ATM buffer dimensioning. Previous studies have shown that video traffic exhibits long-range dependence (LRD) (Hurst parameter large than 0.5). We investigate the practical implications of LRD in the context of realistic ATM traffic engineering by studying ATM multiplexers of VBR video sources over a range of desirable cell loss rates and buffer sizes (maximum delays). Using results based on large deviations theory, we introduce the notion of Critical Time Scale (CTS). For a given buffer size, link capacity, and the marginal distribution of frame size, the CTS of a VBR video source is defined as the number of frame correlations that contribute to the cell loss rate. In other words, second-order behavior at the time scale beyond the CTS does not significantly affect the network performance. We show that whether the video source model is Markov or has LRD, its CTS is finite, attains a small value for small buffer, and is a non-decreasing function of buffer size. Numerical results show that (i) even in the presence of LRD, long-term correlations do not have significant impact on the cell loss rate; and (ii) short-term correlations have dominant effect on cell loss rate, and therefore, well-designed Markov traffic models are effective for predicting Quality of Service (QOS) of LRD VBR video traffic. Therefore, we conclude that it is unnecessary to capture the long-term correlations of a real-time VBR video source under realistic ATM buffer dimensioning scenarios as far as the cell loss rates and maximum buffer delays are concerned.
The effect of repeated sublethal ischemia on NO/cGMP signal transduction system in gray matter of the rabbit spinal cord.

BACKGROUND The activation of the soluble guanylate cyclase and the production of cyclic 3',5'-guanosine monophosphate (cGMP) have been reported as the primary cellular response to nitric oxide (NO) in the nervous system. Previous results indicated, that three-fold sublethal ischemia repeated at 1-h intervals induces damage in gray matter of the spinal cord. However, little is known about the changes of NO/cGMP signal transduction system in gray matter of the spinal cord under conditions of repeated sublethal ischemia. MAIN PURPOSE The aim of this study was to compare the catalytic NOS activity and cGMP concentration in the gray matter regions of lumbosacral spinal cord segments (dorsal horn, zona intermedia, ventral horn) after three (8-, 8-, 9-min) sublethal occlusions repeated at 1-h intervals. METHODS Twenty male rabbits, weighing 2.5-3.5 kg were used in the experiments. They were divided into two experimental groups: (1) control animals (n = 10); (2) animals subjected to three brief (8-, 8-, 9-min) occlusions, each time repeated by reperfusion lasting for 1 h (n = 10). Ischemia of lumbosacral segments was induced by ligation of the abdominal aorta just below the left renal artery (DeGirolami and Zivin, 1982). The catalytic NOS activity was determined by conversion of [3H]-L-arginine to [3H]-L-citrulline according to the method of Bredt and Snyder (1990) slightly modified by Strosznajder and Chalimoniuk (1996). cGMP concentration was assessed by radioimmunoassay method (RIA). RESULTS Repeated sublethal ischemia evoked a slight increase in catalytic NOS activity over control values in all gray matter regions. On the other hand, cGMP concentration in gray matter regions has a decreasing character, in a descending order: dorsal horn > zona intermedia > ventral horn. A significant impairment of NO-cGMP signal transduction was detected in the intermediate zone and ventral horns. CONCLUSIONS Our results indicate that threefold (8-, 8-, 9-min) sublethal ischemia repeated in 1 h intervals of reperfusion causes the impairment of NO/cGMP signal transduction system in gray matter of lumbosacral spinal cord segments and the extent of impairment is region-specific. This finding correlates with the neurological hindlimbs impairment in experimental animals. (Tab. 1, Fig. 2, Ref. 39.)
Empowering Your Sober Self: The LifeRing Approach to Addiction Recovery

Addicted persons are torn between the urge to consume addictive substances and the drive to break with the substances and get free of them. The LifeRing approach anchors itself in the addicted person's drive to get free of the substances and works to empower that urge and to enthrone it permanently in the addicted person's character. Positive peer support focusing on small decisions made in everyday life is the primary psychodynamic engine for recovery in the LifeRing context. Working through nine principal domains, each participant constructs a personal recovery program founded on complete abstinence from all drugs of addiction.
Large-scale Learning of Sign Language by Watching TV (Using Co-occurrences)

The goal of this work is to automatically learn a large number of signs from sign language-interpreted TV broadcasts. We achieve this by exploiting supervisory information available in the subtitles of the broadcasts. However, this information is both weak and noisy and this leads to a challenging correspondence problem when trying to identify the temporal window of the sign. We make the following contributions: (i) we show that, somewhat counter-intuitively, mouth patterns are highly informative for isolating words in a language for the Deaf, and their co-occurrence with signing can be used to significantly reduce the correspondence search space; and (ii) we develop a multiple instance learning method using an efficient discriminative search, which determines a candidate list for the sign with both high recall and precision. We demonstrate the method on videos from BBC TV broadcasts, and achieve higher accuracy and recall than previous methods, despite using much simpler features.
Respect in the neighbourhood: neighbourliness and narratives of decline

The article argues that local social networks are crucial to addressing the perceived shortfall in ‘respect’ and civility. Meanings of ‘respect’ are explored and older people's narratives of the decline of neighbourliness are used to explore the sense that for many people ‘community’ has been lost. It is argued that policy and practice have a role to play in the reinvigoration of local social networks.
Testing the Stability of Self-Control

Gottfredson and Hirschi suggest that individuals’ levels of self-control remain stable over the life course; however, the empirical status of this proposition remains equivocal. Most tests of the stability hypothesis have employed aggregate assessment methods (e.g., mean-level and correlational analyses) that overlook unique developmental patterns, although some have identified unique developmental patterns in self-control. The current study assesses the stability of self-control across 4 years using both traditional analytic methods and methods that account for the existence of unique developmental patterns (i.e., semiparametric group-based trajectory modeling) and exploring risk factors that differentiate these patterns. The results suggest six unique developmental patterns of self-control: two with high stable trajectories and four that evinced lower, less stable trajectories of self-control. The findings indicate that lower, less stable patterns of development are associated with more delinquent peer association, higher rates of parental criminality, fewer school bonds, and weaker maternal attachment.
Teachers and tests: assessing pupils' reading achievement in primary schools

The purpose of the present study was to examine validity aspects of teachers’ judgements of pupils’ reading skills. Data come from Sweden's participation in the Progress in International Reading Literacy Study (PIRLS) 2001, for Grades 3 and 4. For pupils at the same achievement levels, as measured by PIRLS 2001 test, teachers’ judgements of pupils’ achievement levels varied from one teacher to another. Moreover, there were significant differences between teachers’ judgements in Grades 3 and 4. Teachers in Grade 3 who had taught their pupils for almost 3 years showed higher correspondence between their judgements and pupil achievement within classrooms than 4th-grade teachers who, typically, had only taught their pupils for approximately 1 semester at the time of the data collection. The results indicate that teachers’ judgements and tests can be useful within classrooms, but that teachers may need external assessments to calibrate judgements over classrooms.
Explicit B-spline regularization in diffeomorphic image registration

Diffeomorphic mappings are central to image registration due largely to their topological properties and success in providing biologically plausible solutions to deformation and morphological estimation problems. Popular diffeomorphic image registration algorithms include those characterized by time-varying and constant velocity fields, and symmetrical considerations. Prior information in the form of regularization is used to enforce transform plausibility taking the form of physics-based constraints or through some approximation thereof, e.g., Gaussian smoothing of the vector fields [a la Thirion's Demons (Thirion, 1998)]. In the context of the original Demons' framework, the so-called directly manipulated free-form deformation (DMFFD) (Tustison et al., 2009) can be viewed as a smoothing alternative in which explicit regularization is achieved through fast B-spline approximation. This characterization can be used to provide B-spline “flavored” diffeomorphic image registration solutions with several advantages. Implementation is open source and available through the Insight Toolkit and our Advanced Normalization Tools (ANTs) repository. A thorough comparative evaluation with the well-known SyN algorithm (Avants et al., 2008), implemented within the same framework, and its B-spline analog is performed using open labeled brain data and open source evaluation tools.
Public Opinion Versus Public Judgment About Crime: Correcting the 'Comedy of Errors'

This paper builds a case for more defensible assessments of informed public opinion on crime control and penal policy. Mass-mediated portrayals of what the public want and ubiquitous self-selected opinion polls serve as common surrogates for informed public opinion. These highly suspect assessments have gained a level of credence in policy debates that is difficult to justify. Innovations like the Deliberative Poll show promise in facilitating what has been called 'public judgment'-a more reliable and refined state of informed public opinion. Less ambitious remedial proposals, including the public education programmes advocated by some experts and recently embraced by the Home Office, are insufficiently bold to make a significant and lasting impact on public knowledge and attitudes.
Support for Innovation in Historically Black Colleges and Universities

This study explores perceived support for innovation and suggested associated variables among faculty in the context of historically Black colleges and universities (HBCUs). Results showed that faculty perspectives on organizational support for innovation were affected by dispositional resistance toward change, empowerment, organizational trust, interpersonal conflict, and several demographic variables. Organizational trust and experience in terms of participation in innovative processes had major effects on support for innovation. The strategic significance of study findings are discussed.
Design of a force sensing hand for the R1 humanoid robot

This paper outlines the design of the hand of the R1 humanoid robot. The hand uses a completely plastic structure with embedded electronics. It has 2 actuated degrees of freedom (DOF) with 4 phalanges, coupling two phalanges to each degree of actuation. A novel series elastic module was developed within the hand. It is used in force sensing and protects the hand from impact loads. The series elastic module is designed, characterized and evaluated across the working range of the hand. The hand also has position sensors at all joints and tactile sensors for tactile feedback on its phalanges. The hand is completely self-contained with all control boards and motors housed within the structure. It is then tested and evaluated against user needs.
Parental Involvement in Education: The Influence of School and Neighborhood

Abstract Drawing on the life course paradigm, this study views school-based forms of parental involvement in education as elements of the linked lives of family members that are embedded in larger social contexts. Estimating multi-level models on a sample of 6,141 adolescents from the National Longitudinal Study of Adolescent Health, I find that parental participation in school activities and interaction with school personnel is largely a function of the characteristics and behaviors of parents and adolescents, but that, to a lesser extent, these phenomena are influenced by characteristics of the schools that adolescents attend (e.g., school size) and the neighborhoods in which families live (e.g., urbanicity, poverty level). Ethnicity moderates the influence of both school and neighborhood on parents' educational involvement, with minority parents' involvement more contingent on social context, especially school context.
Energy performance profiling of a GPU-based CPM implementation

In recent years, there has been a growing interest in the development of in vitro models to predict cellular behavior within living organisms. Mathematical models, based on differential equations and associated numerical algorithms, have been employed for this purpose. In this study, we present initial forays into the design of parallel strategies aimed at accelerating an algorithm for behavior prediction, specifically based on the Cellular Potts Model. To do this, we engage the computational power of Graphic Processing Units within the CUDA environment to optimize critical low-level kernels.This work intends to provide a comprehensive analysis of the energy performance of the proposed implementation. Tests and experiments affirm significant performance gains in terms of both processing time and substantial energy savings.
Churg-Strauss syndrome with poor-prognosis factors: A prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients.

OBJECTIVE To compare long and short durations of adjunctive cyclophosphamide for the treatment of severe Churg-Strauss syndrome (CSS). METHODS In this prospective multicenter therapeutic trial, 48 patients with CSS with at least 1 poor-prognosis factor at baseline were treated with glucocorticoids and either 12 or 6 intravenous cyclophosphamide pulses. RESULTS At 8 years, complete remission rates and severe side effects of therapy were comparable for both groups. The overall difference in relapses was not significant between the 12-pulse and the 6-pulse regimens (P = 0.07), but when considering only the number of mild relapses this difference became statistically significant (P < 0.02). Although the total number of inclusions was not reached, the study was stopped prematurely in response to the superiority of the 12-pulse regimen. CONCLUSION We concluded that 12 cyclophosphamide pulses were better able to control severe CSS than a 6-pulse regimen. The optimal duration of therapy remains to be determined.