Miracle-dz/UniFAR-FTUs huggingface dataset:
DIFFERENTIAL STRUCTURES ON QUANTUM PRINCIPAL BUNDLES

A fully constructive approach to dierential calculus on quantum principal bundles is presented. The calculus on the bundle is built in an in- trinsic way, starting from given graded (dierential) *-algebras representing horizontal forms on the bundle and dierential forms on the quantum base space, together with a family of antiderivations acting on horizontal forms, playing the role of covariant derivatives of certain special connections. These connections are used as global counterparts of local trivializations. In this conceptual framework, a natural dierential calculus on the structure quan- tum group is described. Higher-order calculi on the structure quantum group coming from both universal envelopes and braided exterior algebras are con- sidered. The structure of a classical smooth manifold is completely expressible in terms of the associated *-algebra of complex-valued smooth functions. Accordingly, it is possible to translate, at least in principle, all concepts and constructions of classical geometry into the language of algebra. This is the starting point of noncommutative dierential geometry (2), where the classical concept of space is essentially enlarged by considering the appropriate non-commutative *-algebras. The elements of these algebras are then interpreted as 'smooth functions' over qualitatively new 'quantum' underlying spaces. In the noncommutative context we meet an interesting new phenomena con- sisting in the existence of various conceptually non-equivalent ways of generalizing basic components of the classical formalism. Though, some fundamental (2) geomet- rical invariants (standard K-groups, cyclic homology and corresponding quantum de Rham cohomology) are uniquely and intrinsically associated to the quantum space algebra. The mentioned non-uniqueness reflects the fact that noncommutative geometry is a much deeper theory, compared with its classical counterpart. This becomes explicitly visible in the foundations of quantum dierential calculus. For example, it is possible to start from the analogs of the vector elds and a natural formulation is to take derivations (3) of the quantum space algebra as counterparts of the vector elds. Then the algebra representing dierential forms can be extracted from the corresponding Chevalley complex. Such a construction is particularly suitable (4, 5) for quantum spaces described by matrix algebras, or for bundles of such spaces over classical smooth manifolds. It is automatically covariant with respect to all classical-type symmetries of the quantum space (described by automorphisms of the quantum space algebra).
Quality of life of patients with familial Mediterranean fever.

OBJECTIVE The aim of the present study was to assess the quality of life (QOL) of patients with Familial Mediterranean Fever (FMF) and to explore its possible contributing factors. METHODS One hundred and two FMF patients were evaluated using a QOL Scale, and were compared to 124 healthy controls. The QOL scale includes 16 items, each measured on a 7-point scale (7 indicating maximal satisfaction). RESULTS The total QOL score of FMF patients was significantly lower than that of the controls: 81.6 +/- 19.2 vs 88.0 +/- 12.8 (p < 0.01). Male and female patients reported similar QOL scores. QOL was inversely correlated with the number of FMF attacks in the last year (r = -0.302, p = 0.002), and with the number of FMF hospitalizations (r = -0.238, p = 0.017). Patients with widespread pain, sleep disturbances and headaches had significantly lower QOL scores than patients without them. CONCLUSIONS The QOL of FMF patients was found to be impaired compared to healthy controls. Further studies are needed to determine the exact factors affecting the quality of life of FMF patients.
Tone of Voice and Mind

Tone of Voice and Mind is a synthesis of findings from neurophysiology (how neurons produce subjective feeling), neuropsychology (how the human cerebral hemispheres undertake complementary information-processing), intonation studies (how the emotions are encoded in the tone of voice), and music perception (how human beings hear and feel harmony). The focus is on the psychological characteristics that distinguish us from other primate species. At a neuronal level, we are just another mammalian species, but the functional specialization of the human cerebral hemispheres has resulted in three outstanding, uniquely-human talents: language, tool-usage and music. To understand how the human brain coordinates those behaviors is to understand who we are. (Series B)
Auditory Discrimination and Classroom Noise.

ronment for considerable portions of the day. Average classroom noise levels have not been adequately de termined relative to occupied and empty room conditions, nor have standards been determined for construction relative to the acoustic environment of classrooms (Knudsen and Harris, 1950; Kingsbury and Taylor, 1967; Hammon, 1970). In one study Kingsbury and Strumpf (1969) advocate a 66 dB noise level as the upper limit to maintain ade quate speech intelligibility (auditory discrimination). Sanders (1965) demonstrated classroom noise levels in relation to grade level and the hearing-impaired. In this study kin dergarten and primary grade classes produced the highest noise levels. Auditory discrimination as a performance skill has been studied most intensely by reading specialists and speech and hearing specialists (Harrington and Durrell, 1955; Dykstra, 1966; Wepman, 1960; Winitz, 1969). Test scores are pertinent to these specialists since reading-defective children show a 20-50 percent incidence range of poor auditory discrimination perfor mance (Durrell, 1956). Similarly, 50-80 percent of speech defective children score poorly on auditory
I Just Can't Do It! The Effects of Social Withdrawal on Prosocial Behavior

I Just Can’t Do It! ” The Effects of Social Withdrawal on Prosocial Behavior Ashley M. Fraser School of Family Life, BYU Master of Science While there has been research published on social withdrawal during childhood, little work has been done on the effects of social withdrawal during emerging adulthood. Since emerging adulthood is a time of transition and initiation to new environments and social contexts, it would be expected to be a time of great anxiety for individuals predisposed to social withdrawal (shyness). Shyer emerging adults are at risk for internalizing behaviors, lowered selfconcept, and delayed entry into romantic relationships, therefore, they may also be more challenged when it comes to enacting prosocial behaviors. In addition, the inability to selfregulate emotions may mediate this relationship. This study utilized a sample of 774 college students (538 women, 236 men; 79% Caucasian; M = 20 years old) to test these hypotheses. Results showed that emerging adults who were more socially withdrawn were less likely to exhibit prosocial behaviors toward strangers, friends, and family members. In addition, results showed that the inability to self-regulate emotions, or cope, mediated this relationship in all cases. Implications include the salience of emotional self-regulation as a prerequisite to prosocial behavior directed toward multiple others and the possibly detrimental influence of shyness on relationship and community involvement during emerging adulthood.
Quantitation of X‐Y homologous genes in patients with schizophrenia by multiplex polymerase chain reaction

Objectives The genetic basis of schizophrenia is obscure. In an XX male patient with schizophrenia we previously showed that one X;Y translocation breakpoint was in pseudoautosomal region 1 (PAR1) with the effect that the proximal segment of PAR1 from the PAR1 boundary to acetylserotonin N‐methyl transferase (ASMT) distally was triplicated in this patient. This study determined whether dosage imbalances of X‐Y homologous regions in general are associated with schizophrenia. Methods A multiplex semi‐quantitative polymerase chain reaction assay was developed to quantify MIC2 gene as a representative of PAR1 and compare it with the SYBL1 gene which maps in pseudoautosomal region 2 (PAR2) and protocadherin XY (PCDHXY), located at Xq21.3. Each of these three loci was co‐amplified with the autosomal gene MSX2 using Cy5‐labelled primers and the products separated by electrophoresis in polyacrylamide gels. Results were expressed as ratios of peak area of the target gene to MSX2 which served as an internal dosage control. Results Using genomes with sex chromosome aneuploidies, the method was found sensitive enough to detect a two‐fold difference in gene copy number. We confirmed the MIC2 triplication in the XX male patient but found no significant difference in gene dosage of MIC2, PCDHXY and SYBL1 in a panel of 17 patients with schizophrenia compared to controls. Conclusions No evidence was obtained for gene dosage imbalances in MIC2, PCDHXY and SYBL1 in patients with schizophrenia. Psychiatr Genet 13:115–119 © 2003 Lippincott Williams & Wilkins.
Rheumatoid arthritis in workers exposed to silica in the pottery industry

OBJECTIVE To investigate the relation between rheumatoid arthritis and occupational exposure to silica in pottery and related industries. METHODS Medical records of 8325 men and women born 1916–45 and employed in pottery, refractory material (aluminosilicate or silica), and sandstone industries were examined to identify cases of rheumatoid arthritis. Medical and employment histories were extracted for cases and matched referents. Indices of duration, cumulative exposure, and mean silica concentration were compiled. Conditional logistic regression was used to investigate the relation between rheumatoid arthritis and indices of exposure, having allowed for potential confounders of smoking, employment in the coal mining industry, and number of pregnancies. RESULTS 58 Cases of rheumatoid arthritis (43 men, 15 women) were identified. Cases had significantly shorter duration of exposure than referents. There was no significant difference between cases and referents in mean silica concentration. Men who had worked in the coal mining industry were particularly at risk (odds ratio 5.36, 95% confidence interval 1.92 to 15.03). CONCLUSION There was no evidence of increased risk of developing rheumatoid arthritis after occupational exposure to silica at mean exposures within the current United Kingdom exposure limits.
Three new species of Saccharomyces sensu lato van der Walt from Yaku Island in Japan: Saccharomyces naganishii sp. nov., Saccharomyces humaticus sp. nov. and Saccharomyces yakushimaensis sp. nov.

Three new yeast species were isolated from soil and partially decayed leaves in Yaku Island and Iriomote Island in the Nansei Islands of Japan. Based on DNA hybridization and physiological characters, these represent novel taxa. These are designated Saccharomyces naganishii sp. nov. (type strain IFO 10181T = CBS 8797T), Saccharomyces humaticus sp. nov. (type strain IFO 10673T = CBS 8893T) and Saccharomyces yakushimaensis sp. nov. (type strain IFO 1889T = CBS 8894T). The phylogenetic relationships of the three new species with members of other ascomycetous genera (e.g. Kluyveromyces, Saccharomyces, Torulaspora and Zygosaccharomyces) were estimated by 18S rDNA gene sequence analysis.
Cerebrospinal fluid exchange after intrathecal methotrexate overdose. A report of two cases

Two patients aged 11 and four years, were accidentally given a 10‐fold overdose of intrathecal methotrexate while being treated for malignant disease. Neither patient developed any signs of neurotoxicity and exchange of lumbar cerebro‐spinal fluid was started 3 and 5 h later, respectively. In one of the patients, who received 120 mg of methotrexate intrathecally, 31% of the given dose was recovered during 2 h of cerebrospinal fluid exchange that was started 3 h after the accidental overdosage. No sequelae were observed in any of the patients. Cerebrospinal fluid exchange is safe and can be recommended in all cases of intrathecal methotrexate overdosage. Ventriculo‐cisternal perfusion is not necessary in cases of a 10‐fold overdose if the patient has no signs of acute neurotoxicity.
An Open-Source Natural Language Generator for OWL Ontologies and its Use in Protege and Second Life

We demonstrate an open-source natural language generation engine that produces descriptions of entities and classes in English and Greek from OWL ontologies that have been annotated with linguistic and user modeling information expressed in RDF. We also demonstrate an accompanying plug-in for the Protege ontology editor, which can be used to create the ontology's annotations and generate previews of the resulting texts by invoking the generation engine. The engine has been embedded in robots acting as museum tour guides in the physical world and in Second Life; here we demonstrate the latter application.
STEALTHMEM: System-Level Protection Against Cache-Based Side Channel Attacks in the Cloud

Cloud services are rapidly gaining adoption due to the promises of cost efficiency, availability, and on-demand scaling. To achieve these promises, cloud providers share physical resources to support multi-tenancy of cloud platforms. However, the possibility of sharing the same hardware with potential attackers makes users reluctant to offload sensitive data into the cloud. Worse yet, researchers have demonstrated side channel attacks via shared memory caches to break full encryption keys of AES, DES, and RSA. We present STEALTHMEM, a system-level protection mechanism against cache-based side channel attacks in the cloud. STEALTHMEM manages a set of locked cache lines per core, which are never evicted from the cache, and efficiently multiplexes them so that each VM can load its own sensitive data into the locked cache lines. Thus, any VM can hide memory access patterns on confidential data from other VMs. Unlike existing state-of-the-art mitigation methods, STEALTHMEM works with existing commodity hardware and does not require profound changes to application software. We also present a novel idea and prototype for isolating cache lines while fully utilizing memory by exploiting architectural properties of set-associative caches. STEALTHMEM imposes 5.9% of performance overhead on the SPEC 2006 CPU benchmark, and between 2% and 5% overhead on secured AES, DES and Blowfish, requiring only between 3 and 34 lines of code changes from the original implementations.
Expression of peroxiredoxin and thioredoxin in human lung cancer and paired normal lung.

BACKGROUND Peroxiredoxins (Prxs) have been implicated in regulating many cellular processes including cell proliferation, differentiation and apoptosis. However, the pathophysiological significance of Prx proteins, especially in lung disease, has not been defined. Therefore, the authors investigated the distribution and expression of various Prx isoforms in lung cancer and compared this with normal lung from human and mouse. METHODS Patients diagnosed with lung cancer who underwent surgery at Ajou Medical Center were enrolled. Expression of Prxs, thioredoxin and thioredoxin reductase was analysed by proteomic techniques. Immunohistochemistry was performed to localize Prx proteins. RESULTS Immunohistochemical staining showed that the isoforms of Prx I, II, III and V were predominantly expressed in bronchial and alveolar epithelium as well as in alveolar macrophages of the normal mouse lung. The isoforms I, III and thioredoxin were overexpressed in lung cancer tissues compared with normal lungs. There was also an increased amount of oxidized form of Prx I and a putative truncated form of Prx III in lung cancer samples when analysed on two-dimensional electrophoresis. In addition, a 40-kDa intermediate MW protein band and high MW bands of over 20 kDa, recognized by anti-Prx (a-Prx) I antibody, were present in tissue extracts of lung cancer patients on one-dimensional electrophoresis. CONCLUSION The upregulation of Prx I, Prx III and thioredoxin in lung cancer tissue may represent an attempt by tumour cells to adjust to the microenvironment in a manner that is advantageous to survival and proliferation.
Liver Metastases From Colorectal Cancer Treated With Conventional and Antiangiogenetic Chemotherapy: Evaluation With Liver Computed Tomography Perfusion and Magnetic Resonance Diffusion-Weighted Imaging

Objective The objectives of the study were to determine whether perfusion computed tomography (CT-p) and magnetic resonance diffusion-weighted imaging (MR-DWI) can allow evaluation of the effects of chemotherapy combined with antiangiogenetic treatment on liver metastases in patients with advanced colorectal cancer and to determine if changes in CT-p and MR-DWI correlate with the response to therapy as assessed by conventional Response Evaluation Criteria in Solid Tumors (RECIST). Methods Eighteen patients with liver metastases from colorectal cancer underwent CT-p and MR-DWI before and 6 months after chemotherapy and antiangiogenetic treatment. Lesions were classified according to RECIST criteria (complete response [CR], partial response [PR], stable disease [SD], and progressive disease) and calculations of CT-p parameters including blood flow (BF), blood volume (BV), capillary permeability (CP), and MR-DWI apparent diffusion coefficient (ADC) values were performed; RECIST, CT-p, and MR-DWI measurements at baseline and follow-up were tested for statistically significant differences using the paired-samples t test. Baseline and follow-up perfusion parameters of the lesions were also compared on the basis of therapy response assessed by RECIST criteria using independent-samples t test. P < 0.05 was considered indicative of a statistically significant difference for all statistical test. Results Six patients (6/18; 33.3%) were classified as PR (Fig. 1), and the remaining 12 (12/18; 66.7%) were classified as SD. On a per-lesion basis, 2 (2/32; 6.3%) cannot be identified at follow-up, 6 (6/32; 18.8%) showed a decrease in size of more than 30%, and 24 (24/32; 75%) were substantially stable in size. No cases of progressive disease were demonstrated at follow-up. No statistically significant differences were demonstrated between PR, CR, and SD lesions for BF (P = 0.19), BV (P = 0.14), and ADC (P = 0.68) measurements, whereas CP was significantly higher in CR and PR lesions (P = 0.038). Considering differences between baseline and follow-up values, no statistically significant differences were noted between PR and CR lesions versus SD lesions for CT-p values (BF: P = 0.77; BV: P = 0.15; CP: P = 0.64). A statistically significant difference between PR and CR lesions and SD lesions was noted for ADC values (P = 0.047). Conclusion Both CT-p and MR-DWI can detect therapy-induced modifications in lesion vascularization before significant changes in size are evident.
Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain‐derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5

Neurotrophins are a family of structurally and functionally related proteins that regulate neuronal survival during development. In the peripheral nervous system (PNS), both in vitro and in vivo studies have shown that neurotrophins are potent factors for the survival of various sensory neurons and sympathetic neurons. However, it is not clear whether all PNS neurons are neurotrophin‐dependent. In the central nervous system (CNS), studies using injury models show that neurotrophins promote the survival of CNS neurons. But mice lacking individual neurotrophins or a combination of BDNF and NT4 did not show significant CNS neuronal loss. Here we derived mice lacking three neurotrophins, brain‐derived growth factor (BDNF), neurotrophin‐3 (NT3), and neurotrophin‐4 (NT4) to study the effect of triple neurotrophin deficiency on peripheral and central neurons. These triple‐deficient mice did not nurse and died within 12 hours after birth. Neuronal cell counts showed that triple mutant pups lacked most of their peripheral sensory neurons and had a statistically significant reduction of motor neurons in several motor nuclei. Our results suggest that neurotrophins are essential for the survival of most peripheral sensory neurons and affect the survival of a small portion of motor neurons during embryogenesis. Dev Dyn;218:94–101. © 2000 Wiley‐Liss, Inc.
Post-it note art: evaluating public creativity at a user generated art installation

As computing increasingly deals with our lived experiences in complex social ecologies such as urban and public environments, designers are challenged with new methods and ways of appropriating computation and experience around public creativity. Public creativity deals with interactions in public interactive installations that are not task-based queries of information but social constructions of user generated and collaborative content. In this paper, we present an analytic framework to evaluate such interactions in public installations. We then present a study where we designed, installed and evaluated a user generated art installation through the lens of this framework.
Do Gender-Specific and High-Resolution Three Dimensional Body Charts Facilitate the Communication of Pain for Women? A Quantitative and Qualitative Study

Background Chronic pain is more prevalent among women; however, the majority of standardized pain drawings are often collected using male-like androgynous body representations. Objective The purpose of this study was to assess whether gender-specific and high-resolution three-dimensional (3D) body charts facilitate the communication of pain for women. Methods Using mixed-methods and a cross-over design, female patients with chronic pain were asked to provide detailed drawings of their current pain on masculine and feminine two-dimensional (2D) body schemas (N=41, Part I) or on female 2D and 3D high-resolution body schemas (N=41, Part II) on a computer tablet. The consistency of the drawings between body charts were assessed by intraclass correlation coefficient (ICC) and Bland-Altman plots. Semistructured interviews and a preference questionnaire were then used to obtain qualitative and quantitative responses of the drawing experience. Results The consistency between body charts were high (Part I: ICC=0.980, Part II: ICC=0.994). The preference ratio for the masculine to feminine body schemas were 6:35 and 18:23 for the 2D to 3D female body charts. Patients reported that the 3D body chart enabled a more accurate expression of their pain due to the detailed contours of the musculature and bone structure, however, patients also reported the 3D body chart was too human and believed that skin-like appearance limited ‘deep pain’ expressions. Conclusions Providing gender-specific body charts may facilitate the communication of pain and the level of detail (2D vs 3D body charts) should be used according to patients’ needs.
Leaning Against the Wind

During financial disruptions, market makers provide liquidity by absorbing external selling pressure. They buy when the pressure is large, accumulate inventories, and sell when the pressure alleviates. This paper studies optimal dynamic liquidity provision in a theoretical market setting with large and temporary selling pressure and order-execution delays. I show that competitive market makers offer the socially optimal amount of liquidity, provided they have access to sufficient capital. If raising capital is costly, this suggests a policy role for lenient central bank lending during financial disruptions. Copyright 2007, Wiley-Blackwell.