Miracle-dz/UniFAR-FTUs huggingface dataset:
A theory of social action: Why personal construct theory needs a superpattern corollary

Kelly's Commonality and Sociality corollaries deal with shared meanings. In this article, the authors revisit Kelly's early work on superpatterns to demonstrate the relationship between superpatterns and the concept of corporate construing (Balnaves & Caputi, 1993) as a way of extending the Commonality and Sociality corollaries. The authors argue that corporate construing is joint action. Constructs in such an action originate from corporate, not personal, agents. Corporate agency entails anticipation in joint action of the mode of representation of everyone else (sensus communis), justification of the joint action (reasons as good reasons), recognition that a personal action is corporate (the same) within a style of reasoning (a system of specialized techniques or corporate constructs). It is not the individual patterns of personal constructs, or an individual's interpretations of his or her own actions, that is relevant in an explanation of personal actions. It is an understanding of the genre, the over.
ErbB-2 and Met Reciprocally Regulate Cellular Signaling via Plexin-B1*

Sema4D-induced activation of plexin-B1 has been reported to evoke different and sometimes opposing cellular responses. The mechanisms underlying the versatility of plexin-B1-mediated effects are not clear. Plexin-B1 can associate with the receptor tyrosine kinases ErbB-2 and Met. Here we show that Sema4D-induced activation and inactivation of RhoA require ErbB-2 and Met, respectively. In breast carcinoma cells, Sema4D can have pro- and anti-migratory effects depending on the presence of ErbB-2 and Met, and the exchange of the two receptor tyrosine kinases is sufficient to convert the cellular response to Sema4D from pro- to anti-migratory and vice versa. This work identifies a novel mechanism by which plexin-mediated signaling can be regulated and explains how Sema4D can exert different biological activities through the differential association of its receptor with ErbB-2 and Met.
An Experimental Comparison of Pregel-like Graph Processing Systems

The introduction of Google's Pregel generated much interest in the field of large-scale graph data processing, inspiring the development of Pregel-like systems such as Apache Giraph, GPS, Mizan, and GraphLab, all of which have appeared in the past two years. To gain an understanding of how Pregel-like systems perform, we conduct a study to experimentally compare Giraph, GPS, Mizan, and GraphLab on equal ground by considering graph and algorithm agnostic optimizations and by using several metrics. The systems are compared with four different algorithms (PageRank, single source shortest path, weakly connected components, and distributed minimum spanning tree) on up to 128 Amazon EC2 machines. We find that the system optimizations present in Giraph and GraphLab allow them to perform well. Our evaluation also shows Giraph 1.0. 0's considerable improvement since Giraph 0.1 and identifies areas of improvement for all systems.
Muscle-Strengthening Activities and Participation Among Adults in the United States

Purpose: To describe those who reported meeting the 2008 Physical Activity Guidelines for Americans (2008 Guidelines) muscle-strengthening standard of 2 or more days per week, including all seven muscle groups, and to assess the type and location of muscle-strengthening activities performed. Method: Data from HealthStyles 2009, a cross-sectional, consumer mail-panel survey, was used for analyses (n = 4,271). The prevalence estimates with 95% confidence intervals of those meeting the 2008 Guidelines standards were calculated. Pairwise t-tests were performed to examine differences between estimates, tests for linear trends were performed among age, education, and body mass index (BMI) groups, and differences and trends were considered statistically significant at p < . 05. Results: Overall, 6.0% of participants reported meeting 2008 Guidelines, and there were no significant differences between sex and racial/ethnic groups. A significant linear increase was noted among education groups, with respondents who reported lower levels of educational attainment having lower levels of participation compared with respondents who reported higher levels of educational attainment. A significant linear decrease was noted among each BMI group, with those classified as underweight/normal reporting higher levels of participation, compared with those classified as obese. Free weights and calisthenics were the most common types of activities; the home was the most common location. Conclusions: Few adults reported meeting current muscle-strengthening standards. Future public health efforts to increase participation should use the most frequently reported type and location of muscle-strengthening activities outlined in this study to guide interventions and communication campaigns.
Genetic and morphological characterization of a Fusarium verticillioides conidiation mutant

Enteroblastic phialidic conidiation by the corn pathogen Fusarium verticillioides (teleomorph Gibberella moniliformis) produces abundant, mostly single-celled microconidia in distinctive long chains. Because conidia might be critical for establishing in planta associations, we characterized a spontaneous F. verticillioides conidiation mutant in which phialides were incapable of enteroblastic conidiogenesis. Instead of producing a conidium, the phialide apex developed a determinate, slightly undulating, germ tube-like outgrowth, in which nuclei rarely were seen. Electron microscopy showed that the apical outgrowth possessed a thick, rough, highly fibrillar outer wall layer that was continuous with the thinner and smoother outer wall layer of the phialide. Both the inner wall layer and plasma membrane also were continuous between the apical outgrowth and phialide. The apical neck region of mutant phialides lacked both a thickened inner wall layer and a wall-building zone, which were critical for conidium initial formation. No indication of septum formation or separation of the apical outgrowth from mutant phialides was observed. These aberrations suggested the apical outgrowth was not a functional conidium of altered morphology. The mutation did not prevent perithecium development and ascosporogenesis. Genetic analyses indicated that a single locus, designated FPH1 (frustrated phialide), was responsible for the mutation. The conidiogenesis mutants were recovered only during certain sexual crosses involving wild-type conidiating parents, and then only in some perithecia, suggesting that mutation of FPH1 might be meiotically induced, perhaps due to mispairing between homologous chromosomes and deletion of the gene from a chromosome.
Beating Bipolar: exploratory trial of a novel Internet-based psychoeducational treatment for bipolar disorder.

OBJECTIVES Psychoeducational approaches are promising interventions for the long-term management of bipolar disorder. In consultation with professionals, patients, and their families we have developed a novel web-based psychoeducational intervention for bipolar disorder called Beating Bipolar. We undertook a preliminary exploratory randomized trial to examine efficacy, feasibility and acceptability. METHODS This was an exploratory randomized controlled trial of Beating Bipolar (current controlled trials registration number: ISRCTN81375447). The control arm was treatment-as-usual and the a priori primary outcome measure was quality of life [measured by the brief World Health Organization Quality of Life (WHOQOL-BREF) scale]. Secondary outcomes included psychosocial functioning, insight, depressive and manic symptoms and relapse, and use of healthcare resources. Fifty participants were randomized to either the Beating Bipolar intervention plus treatment-as-usual or just treatment-as-usual. The intervention was delivered over a four-month period and outcomes were assessed six months later. RESULTS There was no significant difference between the intervention and control groups on the primary outcome measure (total WHOQOL-BREF score) but there was a modest improvement within the psychological subsection of the WHOQOL-BREF for the intervention group relative to the control group. There were no significant differences between the groups on any of the secondary outcome measures. CONCLUSIONS Beating Bipolar is potentially a safe and engaging intervention which can be delivered remotely to large numbers of patients with bipolar disorder at relatively low cost. It may have a modest effect on psychological quality of life. Further work is required to establish the impact of this intervention on insight, knowledge, treatment adherence, self-efficacy and self-management skills.
An Assessment of the Predictive Validity of Impact Factor Scores: Implications for Academic Employment Decisions in Social Work

Objective: Bibliometrics is a method of examining scholarly communications. Concerns regarding the use of bibliometrics in general, and the impact factor score (IFS) in particular, have been discussed across disciplines including social work. Although there are frequent mentions in the literature of the IFS as an indicator of the impact or quality of scholars' work, little empirical work has been published regarding the validity of such use. Method: A proportionate, stratified, random sample, of n=323 articles was selected from 17 Web of Science listed social work journals published during the 1992 to 1994 period. Results: The relationship between journals'IFSs and the actual impact of articles published in those journals (predictive validity) was r= . 41 (short term) and r = . 42 (long term). Conclusion: The practice of using the IFS as a proxy indicator of article impact merits significant concern as well as further empirical investigation.
Cloud bank: A multiple clouds model and its use in MR brain image segmentation

We present improvements to a recently proposed model-based segmentation strategy, called Clouds. We demonstrate the usefulness of the new model Cloud Bank in the automatic MR-image segmentation of the brain (without medulla and spinal cord), the cerebellum, and each brain hemisphere. These structures are connected in several parts, imposing serious challenges for segmentation. The results indicate that the new model is a fast and accurate tool to eliminate user's intervention or, at least, reduce it to simple corrections, in the context of brain image segmentation.
Dissecting the relationship between language skills and learning to read: Semantic and phonological contributions to new vocabulary learning in children with poor reading comprehension

This study investigated individual differences in vocabulary acquisition in 8 – 9-year-old children with impaired reading comprehension. Despite fluent and accurate reading, age-appropriate phonological skills and normal nonverbal ability, poor comprehenders are poor at understanding what they have read, and they show a variety of oral language weaknesses in the non-phonological domain. In this experiment, children were taught to associate new phonological forms to pictures of novel objects (phonological learning) and taught semantic information about the objects (semantic learning). Poor comprehenders needed as many trials as control children to learn phonological forms, suggesting they are well-equipped with the skills needed to learn labels for new objects. However, their knowledge of the meaning of the new words was relatively weak and not well-consolidated over time. These findings suggest that the source of poor comprehenders' difficulties with lexical learning may be localized to the semantic rather than phonological component of vocabulary learning. Implications for understanding the nature of the relationship between reading comprehension and vocabulary skills are discussed.
“My Favorite Things”: A Cross-Cultural Inquiry into Object Attachment, Possessiveness, and Social Linkage

We explore the meaning and histories of favorite objects in two cultures using surveys and photographs. Favorite object attachment is differentiated from the possessiveness component of materialism and from attachment to other people. Meanings of favorite objects derive more from personal memories in the U.S. and from social status in Niger than from object characteristics. Since favorite objects serve as storehouses of personal meanings, gender, age, and culture reflect differences in object selected as well as reasons for selection. In the U.S., photographs show greater proximity to objects that are symbols of others or experiences than to objects enjoyed for their own attributes.
Calcitonin Gene-Related Peptide Induces IL-8 Synthesis in Human Corneal Epithelial Cells1

Calcitonin gene-related peptide (CGRP), a neuropeptide with proinflammatory activities, is released from termini of corneal sensory neurons in response to pain stimuli. Because neutrophil infiltration of the clear corneal surface is a hallmark of corneal inflammation in the human eye, we determined whether CGRP can bind to human corneal epithelial cells (HCEC) and induce expression of the neutrophil chemotactic protein IL-8. It was found that HCEC specifically bound CGRP in a saturable manner with a Kd of 2.0 × 10−9 M. Exposure of HCEC to CGRP induced a significant increase in intracellular cAMP levels and enhanced IL-8 synthesis nearly 4-fold. The capacity of CGRP to stimulate cAMP and IL-8 synthesis was abrogated in the presence of the CGRP receptor antagonist CGRP8–37. CGRP stimulation had no effect on the half-life of IL-8 mRNA while increasing IL-8 pre-mRNA synthesis >2-fold. In contrast to IL-8, CGRP did not induce monocyte chemotactic protein-1 or RANTES synthesis, nor did the neuropeptide enhance detectable increases in steady state levels of mRNA specific for these two β-chemokines. The results suggest that HCEC possess CGRP receptors capable of initiating a signal transduction cascade that differentially activates expression of the IL-8 gene but not the genes for monocyte chemotactic protein-1 or RANTES. The capacity of CGRP to stimulate IL-8 synthesis in HCEC suggests that sensory neurons are involved in induction of acute inflammation at the eye surface.
Stabilization of Fly Ash from Municipal Incinerators

Municipal solid waste incinerator by-products include fly ash and air pollution control residues. In order to transform these wastes into reusable species, soluble alkali chlorides must be separated and toxic trace elements must be stabilized. In this paper, alkali chlorides can be extracted efficiently in an aqueous extraction step combining a calcium phosphate gel precipitation. In such a process, sodium and potassium chlorides are obtained free from calcium salts, and the trace metal ions are immobilized in the calcium phosphate matrix. Fly ash spiked with copper ions and treated by this process shows improved stability of metal ions. Leaching tests with water or EDTA reveal a significant drop in metal ion dissolution.
The Dark Side of Competition for Status

Unethical behavior within organizations is not rare. We investigate experimentally the role of status-seeking behavior in sabotage and cheating activities aiming at improving one’s performance ranking in a flat-wage environment. We find that average effort is higher when individuals are informed about their relative performance. However, ranking feedback also favors disreputable behavior. Some individuals do not hesitate to incur a cost to improve their rank by sabotaging others’ work or by increasing artificially their own performance. Introducing sabotage opportunities has a strong detrimental effect on performance. Therefore, ranking incentives should be used with care. Inducing group identity discourages sabotage among peers but increases in-group rivalry. (This abstract was borrowed from another version of this item.)
Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B.

PURPOSE To examine the individual and joint effect of various pretreatment clinical characteristics on the survival of patients with mesothelioma treated by the Cancer and Leukemia Group B (CALGB). PATIENTS AND METHODS Between June 1984 and September 1994, 337 patients with malignant mesothelioma and no prior chemotherapy were accrued to seven phase II studies conducted by the CALGB which screened the efficacy of 10 treatment regimens or dose levels. The eligibility criteria for all studies were virtually identical. Patient characteristics include the following: age older than 60 years (63%); male (83%); performance status (PS) of 0 or 1 (81%); chest pain (60%); definite asbestos exposure (62%); >5% weight loss (41%); and pleural involvement (94%). Median survival time (MST) for the 10 treatment regimens ranged from 3.9 to 9.8 months (overall=7.2; 95% confidence interval [CI], 6.5 to 8.3), with 1-year survival between 14% and 50% (overall=27%; 95% CI, 23 to 33%). RESULTS Cox survival models and exponential regression trees were used to examine the prognostic importance of pretreatment patient characteristics. Univariate analyses show that patients with poor Eastern Cooperative Oncology Group PS, chest pain, dyspnea, platelet count (PLT) >400,000/microL, weight loss, serum lactate dehydrogenase (LDH) level >500 IU/L, pleural involvement, low hemoglobin (HGB) level, high WBC count, and increasing age over 75 years have a worse prognosis. With decreasing risk ratio, multivariate Cox analyses showed that pleural involvement, LDH >500 IU/L, poor PS, chest pain, PLT >400,000/microL, nonepithelial histology, and increasing age older than 75 years jointly predict poor survival. PS was the most important prognostic split in the regression tree. Terminal nodes were amalgamated to form six distinct prognostic subgroups with MST (2-year survival) of 13.9 (38%) in 36 patients, 9.5 (21%) in 36 patients, 9.2 (10%) in 146 patients, 6.5 (3%) in 33 patients, 4.4 (0%) in 73 patients, and 1.4 (0%) in 13 patients (p<0.0001). CONCLUSIONS The subgroup with the best survival (MST=13.9 months) included patients with PS=0 and age younger than 49 years, and patients with PS=0, age of 49 years or older, and HGB > or =14.6. The worst survival (MST= 1.4 months) occurred for patients with PS= 1/2 and WBC > or =15.6/microL.
Beyond mood and modality: epistemic modality markers as hedges in research articles. A cross-disciplinary study

In this paper a cross-disciplinary study of the use of epistemic markers as hedging rhetorical strategies in research articles in English is carried out. Based on computer readable data, and combining quantitative and qualitative methods, the article argues that the use of modal expressions can be better explained as reflecting the strategies of hedging used by writers for dealing with the social conditions involved in the event of publishing an article, which is addressed to different discourse communities. Three different disciplines (Marketing, Biology and Mechanical Engineering) belonging to the soft knowledge vs. hard knowledge discipline continuum are investigated here. Our analysis of hedging in these three different disciplines has revealed, not only that there are differences in the occurrence of hedges in the RAs selected, but also that these differences depend on the nature of the data used for the research in each discipline. Each discipline tries to fulfil social needs in different areas. The sociological features of each discipline may be shaping the discourse in their RAs differently. This is reflected in the varied presence of hedging devices in Marketing, Biology and Mechanical Engineering research articles.
EARLY AGE PROPERTIES OF PORTLAND CEMENT PASTES INVESTIGATED WITH ULTRASONIC SHEAR WAVES AND NUMERICAL SIMULATION

In this paper, the correlation of reflection loss measured by an ultrasonic shear wave reflection method and the microstructure in cement-based material is investigated. Three cement pastes (Portland cement type I) with different water-cement ratios (0.35, 0.50 and 0.60) cured at 25 °C were examined. The ultrasonic shear wave reflection factor (WRF) was measured by the wave reflection technique. Reflection loss was calculated based on WRF measurement. Initial and final setting time were obtained by Vicat Needle tests. Thermogravimetric tests were conducted to observe the hydration process of cement pastes. To obtain the evolution of the microstructure in cement pastes, a numerical cement hydration model, HYMOSTRUC3D, was applied. Correlations between the microstructural evolution (e.g. growing of solid phases, percolation threshold of solid phases, and capillary porosity) calculated by HYMOSTRUC3D model and the reflection loss have been established. From this study, it was found that the WRF behavior is closely related to the microstructural evolution, such as, the total solid phase volume, the connectivity of solid phase and the pore structure. The study shows that, the wave reflection technique, as a non-destructive testing method, can be used to monitor the microstructural evolution of cementitious materials at early ages.
A theoretical and experimental examination of systematic ligand-induced disorder in Au dendrimer-encapsulated nanoparticles

In this paper we present a new methodology for the analysis of 1–2 nm nanoparticles using extended X-ray absorption fine structure (EXAFS) spectroscopy. Different numbers of thiols were introduced onto the surfaces of dendrimer-encapsulated Au nanoparticles, consisting of an average of 147 atoms, to systematically tune the nanoparticle disorder. An analogous system was investigated using density functional theory molecular dynamics (DFT-MD) simulations to produce theoretical EXAFS signals that could be directly compared to the experimental results. Validation of the theoretical results by comparing to experiment allows us to infer previously unknown details of structure and dynamics of the nanoparticles. Additionally, the structural information that is learned from theoretical studies can be compared with traditional EXAFS fitting results to identify and rationalize any errors in the experimental fit. This study demonstrates that DFT-MD simulations accurately depict complex experimental systems in which we have control over nanoparticle disorder, and shows the advantages of using a combined experimental/theoretical approach over standard EXAFS fitting methodologies for determining the structural parameters of metallic nanoparticles.
Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening.

AIM To determine whether single nucleotide polymorphisms (SNPs) can be used to identify people who should be screened for colorectal cancer. METHODS We simulated one million people with and without colorectal cancer based on published SNP allele frequencies and strengths of colorectal cancer association. We estimated 5-year risks of colorectal cancer by number of risk alleles. RESULTS We identified 45 SNPs with an average 1.14-fold increase colorectal cancer risk per allele (range: 1.05-1.53). The colorectal cancer risk for people in the highest quintile of risk alleles was 1.81-times that for the average person. CONCLUSION We have quantified the extent to which known susceptibility SNPs can stratify the population into clinically useful colorectal cancer risk categories.