Miracle-dz/UniFAR-FTUs huggingface dataset:
Stepped collaborative care for primary care patients with persistent symptoms of depression: a randomized trial.

BACKGROUND Despite improvements in the accuracy of diagnosing depression and use of medications with fewer side effects, many patients treated with antidepressant medications by primary care physicians have persistent symptoms. METHODS A group of 228 patients recognized as depressed by their primary care physicians and given antidepressant medication who had either 4 or more persistent major depressive symptoms or a score of 1.5 or more on the Hopkins Symptom Checklist depression items at 6 to 8 weeks were randomized to a collaborative care intervention (n = 114) or usual care (n = 114) by the primary care physician. Patients in the intervention group received enhanced education and increased frequency of visits by a psychiatrist working with the primary care physician to improve pharmacologic treatment. Follow-up assessments were completed at 1, 3, and 6 months by a telephone survey team blinded to randomization status. RESULTS Those in the intervention group had significantly greater adherence to adequate dosage of medication for 90 days or more and were more likely to rate the quality of care they received for depression as good to excellent compared with usual care controls. Intervention patients showed a significantly greater decrease compared with usual care controls in severity of depressive symptoms over time and were more likely to have fully recovered at 3 and 6 months. CONCLUSIONS A multifaceted program targeted to patients whose depressive symptoms persisted 6 to 8 weeks after initiation of antidepressant medication by their primary care physician was found to significantly improve adherence to antidepressants, satisfaction with care, and depressive outcomes compared with usual care.
A Meta-Analysis Comparing Breast Conservation Therapy Alone to the Oncoplastic Technique

AbstractWhen immediate reconstruction is applied to breast conservation therapy (BCT), the benefits extend well beyond the minimization of poor cosmetic results. The purpose of this analysis was to compare literature outcomes between BCT alone and BCT with the oncoplastic approach. MethodsA meta-analysis was performed in PubMed using key words “oncoplastic,” “partial breast reconstruction,” and “breast conservation therapy. ” Case reports, series with less than 10 patients, and those with less than 1-year follow-up were excluded from the analysis. The 3 comparative groups included BCT with oncoplastic reduction techniques (Group A), BCT with oncoplastic flap techniques (Group B), and BCT alone (Group C). ResultsComparisons were made on 3165 patients in the BCT with oncoplastic group (Groups A and B, 41 papers) and 5494 patients in the BCT alone group (Group C, 20 papers). Demographics were similar, and tumor size was larger in the oncoplastic group (2.7 vs 1.2 cm). The weight of the lumpectomy specimen was 4 times larger in the oncoplastic group. The positive margin rate was significantly lower in the oncoplastic group (12% vs 21%, P < 0.0001). Reexcision was more common in the BCT alone group (14.6% vs 4%, P < 0.0001), however, completion mastectomy was more common in the oncoplastic group (6.5% vs 3.79%, P < 0.0001). The average follow-up was longer in the BCT alone group (64 vs 37 months). Local recurrence was 4% in the oncoplastic group and 7% in the BCT alone group. Satisfaction with the aesthetic outcome was significantly higher in the oncoplastic group (89.5% vs 82.9%, P < 0.001). ConclusionsThe oncoplastic approach to BCT allows a generous resection with subsequent reduction in positive margins. The true value on local recurrence remains to be determined. Patients are more satisfied with outcomes when the oncoplastic approach is used.
Participatory music-making and well-being within immigrant cultural practice: exploratory case studies in South East Queensland, Australia

ABSTRACT Music participation is a way of life for many cultures and is an activity that is often passed on generationally. It can become especially important as a leisure activity for maintenance of self- and national identity for people who have migrated to countries of contrasting cultures, such as Australia. This article describes exploratory, qualitative research into the ways in which participatory music-making within communities from immigrant backgrounds in Brisbane, Australia may influence aspects of participants’ wellbeing. The sample for this research included three broadly-defined cultural groups living in the region: people of Baltic origin; people from Latin American and Caribbean backgrounds; and ‘newly arrived’ immigrants and refugees. Interviews with individuals have been analysed to explore the ways in which this involvement might affect mental, social, and emotional wellbeing. Our qualitative analyses demonstrated that beyond these aspects, factors of subjective wellbeing, both hedonic and eudaimonic, were apparent. This article aims to provoke discussions on the divergent ways in which immigrant communities utilise music-making practices to foster different types of wellbeing and the importance of maintaining diversity through cultural practices.
Using Inquiry-Based Laboratory to improve students’ Higher Order Thinking Skills (HOTs)

Higher order thinking skills (HOTs) is 21st century learning trend. This study to determine the effect of inquiry-based laboratory on the Students’ HOTs in learning harmonic vibration. The method used descriptive quantitative true-experiment. Sampling technique using randomized control group pre-test and post-test design. The sample was 69 students, consisting of two experimental groups (n = 46 students) and one control group (n = 23 students). The experimental group is taught by inquiry-based laboratory activities, while the control group is taught by not inquiry-based laboratory activities. The result of this research shows that the experimental groups got gain score are 0.57 and 0.54, while the control group got gain score is 0.13 and both groups proved to have statistically significant different improvement. It means experimental groups have ability to Analyse, evaluation and create.
Countable models of stable theories

The notion of a normal theory is lntroduced, and it is proved that for such a theory T, J(t8, T) I or ? 8. We also include a short proof of Lachlan's theorem that for superstable T, J(8), T) = I or ? 8(. (The property of normality is stronger than stability but incomparable to superstability.) 1. Preliminaries. We consider here theories T which are countable and complete (and of course finitary, first order). A long standing question is whether for stable, not M%-categorical T, T must always have infinitely many countable models (up to isomorphism). This was answered positively by Lachlan [1] for T superstable, and other proofs in this case have been given by Lascar [3] and Shelah [7]. Here we consider theories which satisfy, in effect, a stronger combinatorial property than "not having the order property", and answer the question positively for such theories, strengthening results in Pillay [6]. I wish to thank the referee for his suggestions, especially concerning the proof of Lemma 4 and an error in our earlier formulation of Lemma 6. DEFINITION 1. (i) The L-formula a(x-, yj) is T-normal (or just normal) if for any a, b in a model M of T the definable subsets a(x-, a-) and a(x-, b) are either disjoint or equal. (ii) T is normal if every L-formula is equivalent modulo T to a Boolean combination of normal formulae (i.e. formulae that are normal no matter how we separate the variables). (Our use of the word normal is motivated by the normal formulas of Lachlan [2], but our notion is of course much cruder.) It is easy to see that a normal theory is stable, either by counting types (if a(x, V ) is normal then there can be at most X a-types over any model of power A) or by observing that a normal formula does not have the order property and thus neither does any Boolean combination of such formulae. Clearly, any theory of equivalence relations E, which has eliminnation of quantifiers is normal, and thus there are normal theories which are o-stable, strictly superstable and strictly stable. Any theory of R-modules is normal, as a consequence of Baur's "p.p elimination of quantifiers" for modules, and the fact that in an R-module M, if p(x, y-) is a p.p (positive primitive) formula, then for any a E M q4(x-, ia) defines (if consistent) a coset of the subgroup Received by the editors November 30, 1982. Part of the contents of this paper was presented at the 797th meeting of the A. M. S. at the University of Maryland. October 1982. 1980 Mathernatics Subject Classificatiotn. Primary 03C45; Secondary 03C15. Key wvords aid phrases. Normal theory, superstable. ISupported by a grant from the NSERC of Canada. (1983 American Mathematical Society 0002-9939/83 $1.00 + $. 25 per page
Multicentre randomised control trial comparing real time teledermatology with conventional outpatient dermatological care: societal cost-benefit analysis

Abstract Objectives: Comparison of real time teledermatology with outpatient dermatology in terms of clinical outcomes, cost-benefits, and patient reattendance Design: Randomised controlled trial with a minimum follow up of three months. Setting: Four health centres (two urban, two rural) and two regional hospitals Subjects: 204 general practice patients requiring referral to dermatology services; 102 were randomised to teledermatology consultation and 102 to traditional outpatient consultation. Main outcome measures: Reported clinical outcome of initial consultation, primary care and outpatient reattendance data, and cost-benefit analysis of both methods of delivering care. Results: No major differences were found in the reported clinical outcomes of teledermatology and conventional dermatology. Of patients randomised to teledermatology, 55 (54%) were managed within primary care and 47 (46%) required at least one hospital appointment. Of patients randomised to the conventional hospital outpatient consultation, 46 (45%) required at least one further hospital appointment, 15 (15%) required general practice review, and 40 (39%) no follow up visits. Clinical records showed that 42 (41%) patients seen by teledermatology attended subsequent hospital appointments compared with 41 (40%) patients seen conventionally. The net societal cost of the initial consultation was £132.10 per patient for teledermatology and £48.73 for conventional consultation. Sensitivity analysis revealed that if each health centre had allocated one morning session a week to teledermatology and the average round trip to hospital had been 78 km instead of 26 km, the costs of the two methods of care would have been equal. Conclusions: Real time teledermatology was clinically feasible but not cost effective compared with conventional dermatological outpatient care. However, if the equipment were purchased at current prices and the travelling distances greater, teledermatology would be a cost effective alternative to conventional care
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Data Don't Drive: Building a Practitioner-Driven Culture of Inquiry to Assess Community College Performance. Lumina Foundation for Education Research Report.

CCSSP was sponsored by Lumina Foundation for Education as part of the Foundation's ongoing efforts to enhance the success of students in the nation's community colleges. The report also is informed by members of CCSSP's National Advisory Council, by a Think Tank convened by the New England Resource Center for Higher Education (NERCHE) and by research associates who are practitioners in community colleges. The author acknowledges helpful information and insights provided in response to earlier drafts of this paper The views expressed are those of the author and do not necessarily represent those of Lumina Foundation, its officers or other contributors to the project. DEDICATION: This report is dedicated to Dan Walleri, a member of CCSSP's National Advisory Council until his passing in the summer of 2005. His thoughtful contributions, sound advice and steady vision are greatly missed by all who had the pleasure to work with him.
Regional price deflators for VHLSS 2008-2010 and GSO capacity building for spatial cost of living index

Since 1992, Vietnam has conducted six household living standards surveys (VLSS and VHLSS), which have been extensively used in poverty analysis and monitoring. The first of these surveys, in 1992-93 collected detailed price information in the sampled enumeration areas (EAs) as part of the community questionnaire. These community market prices were an important source of information, either solely or in conjunction with household-unit values (expenditures divided by quantities, which are available for foods in the VHLSS), on regional differences in prices and the cost of living. Estimates of these regional differences are needed especially for deflating nominal expenditures prior to those expenditures being compared with a national poverty line (or equivalently, for converting a national poverty line into regional prices to compare with nominal expenditures). The implementation of the Consumer Price Index (CPI) data collection has also undergone substantial changes over the last decade in Vietnam. The number of goods and services in the market basket has increased substantially, to 496 currently, of which 82 are designed to have their prices surveyed every 10 days. But for almost all of the items in the current market basket, the detailed specification, category and brand, whose price is collected either every 10 days or every month, is selected to suit the peculiarities of consumer demand in each province rather than selected to be consistent across all price collection localities in Vietnam. This situation has not always prevailed; the market basket used from 2000-2005 had ca. 30 items that were nationally consistent (that is, all of the provincial statistical offices were instructed to collect prices for the same detailed specification) with the balance of items being peculiar to each province. But since the beginning of 2006 the choice of detailed specification for all of the items in the market basket has been devolved to the provinces. Note that this lack of comparability across space in the definition of the surveyed goods and services is not necessarily problematic for a temporal index like the CPI, which just requires consistency of the specification over time.
Fuzzy model predictive control

A fuzzy model predictive control (FMPC) approach is introduced to design a control system for a highly nonlinear process. In this approach, a process system is described by a fuzzy convolution model that consists of a number of quasi-linear fuzzy implications. In controller design, prediction errors and control energy are minimized through a two-layered iterative optimization process. At the lower layer, optimal local control policies are identified to minimize prediction errors in each subsystem. A near optimum is then identified through coordinating the subsystems to reach an overall minimum prediction error at the upper layer. The two-layered computing scheme avoids extensive online nonlinear optimization and permits the design of a controller based on linear control theory. The efficacy of the FMPC approach is demonstrated through three examples.
Buying time for better decision-making: the impact of home based rehabilitation on frail older people

Often, life-changing decisions regarding the long-term care needs of frail older patients are taken at vulnerable times when they are ill or hospitalized. Consequently, patients may be placed inappropriately in institutional care where it is difficult to regain the skills or confidence needed to return home. This paper presents findings from an evaluation of a service that extends the period of decision making about patients needs by providing a rehabilitative package of care in the patient's own home. Participants comprised two groups; older people who received the rehabilitation service (n=56) and a comparator group of similar older people who received a care managed service (n=56). All participants completed a series of measures at three time-points. These measures included an assessment of functioning, a measure of quality of life and, a measure of service utilization. On discharge, rehabilitation clients experienced significant improvements relative to care- managed clients on all functional measures (FIM, P=.014; CDI, P=.001; EASY, P=.001); quality of life (P=.003); and, service utilization and cost (P=.001). In addition, carers of rehabilitation service users reported significantly less stress than carers of care-managed patients (P=.007). These results show that the rehabilitation service succeeded in improving functioning and helped to create a longer time-period during which older people, their carers and professionals could make appropriate decisions about their future care needs.
MODELING THE CO-OCCURRENCE PRINCIPLES OF THE CONSONANT INVENTORIES: A COMPLEX NETWORK APPROACH

Speech sounds of the languages all over the world show remarkable patterns of co-occurrence. In this work, we attempt to automatically capture the patterns of co-occurrence of the consonants across languages and at the same time figure out the nature of the force leading to the emergence of such patterns. For this purpose we define a weighted network where the consonants are the nodes and an edge between two nodes (read consonants) signify their co-occurrence likelihood over the consonant inventories. Through this network we identify communities of consonants that essentially reflect their patterns of co-occurrence across languages. We test the goodness of the communities and observe that the constituent consonants frequently occur in such groups in real languages also. Interestingly, the consonants forming these communities reflect strong correlations in terms of their features, which indicate that the principle of feature economy acts as a driving force towards community formation. In order to measure the strength of this force we propose a theoretical information definition of feature economy and show that indeed the feature economy exhibited by the consonant communities are substantially better than that of those where the consonant inventories had evolved just by chance.
A morphometric study of the middle and lower cervical vertebral endplates and their components

Abstract Cervical disc arthroplasty is a common method of treating cervical degenerative disease. However, the footprints of most prosthesis dimensions are obtained from data of Caucasian individuals. Besides, there is a large discrepancy between footprints of currently available cervical disc prostheses and anatomic dimensions of cervical endplates. We aimed to detail the three-dimensional (3D) anatomic morphology of the subaxial cervical vertebral endplate, utilizing high-precision, high-resolution scanning equipment, and provide a theoretical basis for designing appropriate disc prostheses for Chinese patients. A total of 138 cervical vertebral endplates were studied. Each endplate was digitized using a non-contact optical 3D range scanning system and then reconstructed to quantify diameters and surface area for the whole endplate and its components (central endplate and epiphyseal rim). The whole endplate and mid-plane concavity depth were measured. There is marked morphologic asymmetry, in that the cranial endplate is more concave than the corresponding caudal endplate, with endplate concavity depths of 2.04 and 0.69 mm, respectively. For the caudal endplates, the endplate concavity apex locations were always located in the posterior portion (81.42%), while in cranial endplates relatively even. The central endplate was approximately 60% of the area of the whole endplate and the anterior section of the ring was the widest. From C3/4 down to C6/7 discs, the vertebral endplate gradually became more elliptical. Chinese cervical endplate anatomic sizes are generally smaller than that of Caucasians. Although Korean and Chinese individuals both belong to the Asian population subgroup, the majority of anatomic dimensions differ. Singaporean cervical endplate morphology is very similar to that of Chinese patients. We performed a comprehensive and accurate quantitative description of the cervical endplate, which provide references to shape and profile an artificial cervical disc without sacrificing valuable bone stock. To design a device with footprint as large as possible to distribute the axial load, we suggest that additional attention should be paid to the marginal rim. It is essential to specifically design appropriate disc prosthesis for Chinese patients. To fit the morphologic and biomechanical variations, we also propose that the disc prostheses for different vertebral segments should be separately designed.
Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow

GAS6 and its receptors (Tryo 3, Axl, Mer or “TAM”) are known to play a role in regulating tumor progression in a number of settings. Previously we have demonstrated that GAS6 signaling regulates invasion, proliferation, chemotherapy-induced apoptosis of prostate cancer (PCa) cells. We have also demonstrated that GAS6 secreted from osteoblasts in the bone marrow environment plays a critical role in establishing prostate tumor cell dormancy. Here we investigated the role that endogenous GAS6 and Mer receptor signaling plays in establishing prostate cancer stem cells in the bone marrow microenvironment. We first observed that high levels of endogenous GAS6 are expressed by disseminated tumor cells (DTCs) in the bone marrow, whereas relatively low levels of endogenous GAS6 are expressed in PCa tumors grown in a s.c. setting. Interestingly, elevated levels of endogenous GAS6 were identified in putative cancer stem cells (CSCs, CD133+/CD44+) compared to non-CSCs (CD133–/CD44–) isolated from PCa/osteoblast cocultures in vitro and in DTCs isolated from the bone marrow 24 hours after intracardiac injection. Moreover, we found that endogenous GAS6 expression is associated with Mer receptor expression in growth arrested (G1) PCa cells, which correlates with the increase of the CSC populations. Importantly, we found that overexpression of GAS6 activates phosphorylation of Mer receptor signaling and subsequent induction of the CSC phenotype in vitro and in vivo. Together these data suggest that endogenous GAS6 and Mer receptor signaling contribute to the establishment of PCa CSCs in the bone marrow microenvironment, which may have important implications for targeting metastatic disease.