Miracle-dz/UniFAR-FTUs huggingface dataset:
DISC: Deep Image Saliency Computing via Progressive Representation Learning

Salient object detection increasingly receives attention as an important component or step in several pattern recognition and image processing tasks. Although a variety of powerful saliency models have been intensively proposed, they usually involve heavy feature (or model) engineering based on priors (or assumptions) about the properties of objects and backgrounds. Inspired by the effectiveness of recently developed feature learning, we provide a novel deep image saliency computing (DISC) framework for fine-grained image saliency computing. In particular, we model the image saliency from both the coarse-and fine-level observations, and utilize the deep convolutional neural network (CNN) to learn the saliency representation in a progressive manner. In particular, our saliency model is built upon two stacked CNNs. The first CNN generates a coarse-level saliency map by taking the overall image as the input, roughly identifying saliency regions in the global context. Furthermore, we integrate superpixel-based local context information in the first CNN to refine the coarse-level saliency map. Guided by the coarse saliency map, the second CNN focuses on the local context to produce fine-grained and accurate saliency map while preserving object details. For a testing image, the two CNNs collaboratively conduct the saliency computing in one shot. Our DISC framework is capable of uniformly highlighting the objects of interest from complex background while preserving well object details. Extensive experiments on several standard benchmarks suggest that DISC outperforms other state-of-the-art methods and it also generalizes well across data sets without additional training. The executable version of DISC is available online: <;uri xlink:type="simple">http://vision.sysu. edu.cn/projects/DISC<;/uri>.
CD 4 1 and CD 8 1 T Cells Make Discrete Contributions to Demyelination and Neurologic Disease in a Viral Model of Multiple Sclerosis

Following intracerebral infection with Theiler’s murine encephalomyelitis virus (TMEV), susceptible strains of mice (SJL and PLJ) develop virus persistence and demyelination similar to that found in human multiple sclerosis. Resistant strains of mice (C57BL/6) clear virus and do not develop demyelination. To resolve the controversy about the role of CD4 and CD8 T cells in the development of demyelination and neurologic deficits in diseases of the central nervous system, we analyzed TMEV infection in CD4and CD8-deficient B6, PLJ, and SJL mice. Genetic deletion of either CD4 or CD8 from resistant B6 mice resulted in viral persistence and demyelination during the chronic stage of disease. Viral persistence and demyelination were detected in all strains of susceptible background. Although genetic deletion of CD8 had no effect on the extent of demyelination in susceptible strains, deletion of CD4 dramatically increased the degree of demyelination observed. Whereas strains with deletions of CD4 showed severe neurologic deficits, mice with deletions of CD8 showed minimal or no deficits despite demyelination. In all strains, deletion of CD4 but not CD8 resulted in a decreased delayed-type hypersensitivity response to viral antigen. We conclude that each T-cell subset makes a discrete and nonredundant contribution to protection from viral persistence and demyelination in resistant strains. In contrast, in susceptible strains, CD8 T cells do not provide protection against chronic demyelinating disease. Furthermore, in persistent TMEV infection of the central nervous system, neurologic deficits appear to result either from the absence of a protective class II-restricted immune response or from the presence of a pathogenic class I-restricted response.
Overt and Covert Recognition of Faces in Children and Adults

There has been considerable recent interest in covert face-recognition effects In Experiment 1, we adapted a paradigm, previously shown to produce covert recognition effects, to test 5-year-old children Classmates' photographs served as the familiar faces Children showed effects of familiarity on face matching similar to the effects normal adults and prosopagnosics had previously shown for famous faces In Experiment 2, we investigated whether brief familiarization with the photographs used in Experiment I would suffice to produce the effects, in children and adults It did not, even though the exposure did lead to above-chance overt recognition Taken together with previous studies, the data suggest that covert recognition may be doubly dissociable from overt recognition Finding a double dissociation would place constraints on models of face recognition
The real relationship in psychotherapy: Relationships to adult attachments, working alliance, transference, and therapy outcome.

The purpose of this study was to understand how the real relationship (RR) relates to important process and outcome variables from both the clients' and therapists' perspectives. Using a sample of 31 therapist/client dyads at a university counseling center, the authors examined the RR at the 3rd session of therapy and at termination. The results revealed that client adult attachment avoidance was negatively correlated with client RR, while client adult attachment anxiety was uncorrelated. Therapists' ratings of negative transference were negatively correlated with therapist-rated RR and were uncorrelated with client-rated RR. Hierarchical linear modeling analyses were conducted to predict postintervention outcome from client and therapist perceptions of the RR. Therapists' ratings of the RR accounted for a significant amount of variance in client posttreatment symptoms while controlling pretreatment symptoms. Client-rated RR total scores and client and therapist 3rd-session alliance scores were not significant predictors of postsymptom ratings. Implications of the usefulness of measuring the RR in psychotherapy are discussed, as are recommendations for future study.
Trust schools and the politics of persuasion and the mobilisation of interest

This paper sets out the theoretical and methodological approach of a study of the politics of persuasion and the mobilisation of interest in relation to the Trust schools initiative in England. Drawing on the discourse theoretical approach of Laclau and Mouffe the paper argues that the politics of consensus associated with New Labour reconfigures the field of politics, closing down legitimate democratic space. Building on this approach and that of policy sociology the paper outlines how the researchers seeks to address the following questions – if the space for legitimate democratic debate is so severely constrained then how does a social democratic government deal with the kind of opposition that Labour faced in relation to Trust schools? How do governments persuade dissident citizens to support unpopular policies? How are citizens mobilised to support such policies? This also raises questions about how, in such a restricted political space, do those questioning or resisting such policies, engage in the politics of persuasion and the mobilisation of interests? The reconfiguration of the field of politics and what this means for the constitution of legitimate democratic debate is the object of study of the research.
Predictors of Categorical At‐Risk High School Dropouts

The authors attempted to identify key contributing factors to school dropout among 3 categories of at-risk students: those with low grade point averages, those who had been suspended, and those from low socioeconomic backgrounds. Logistic regression analysis of the data, which were derived from the National Longitudinal Survey of Youth-1997 (U.S. Bureau of Labor Statistics, 2002) indicated that student dropout rates were affected differently by students' membership in the 3 at-risk categories.
Psychosocial culture and pathways to psychological injury within policing

This study explored the evolution of work‐related psychological injury in policing, focusing on the role of police psychosocial culture. In addition to primary interview data from 19 former officers, 4 focus groups and 17 spontaneous written submissions were sources of triangulation. Whether sustained as a result of traumatic stress experience or via the more common erosive stress pathway, the psychosocial context surrounding operational policing played a critical role in psychological injury development and progression. The mitigation of psychological injury within policing requires that meaningful efforts be directed at challenging the cultural imperative towards emotional control and improving organization‐wide psychosocial care.
What do teachers need? Practitioners' perspectives on early childhood professional development

Abstract Because of the link between teacher training and higher‐quality classroom practice, early childhood researchers and professional organizations have placed an increasing emphasis on all early childhood teachers—including those in early care and education (ECE) settings—obtaining a minimum of a Bachelor's degree as part of their professional development. Given the differing licensure requirements for ECE teachers, the variety of settings early childhood teachers work in, and the creativity needed to respond to the changing roles teachers play in those settings, however, this paper offers an additional perspective that is sometimes left out of the discussion regarding what teachers need: that of the early childhood practitioner. Using conversations with both a certified, public school teacher and a non‐certified teacher in a private ECE setting in New Jersey, this article reports on these teachers’ professional development experiences, as well as the implications of their experiences for future considerations of what teachers need in order to enhance their growth as educators.
Outcome After Surgical Treatment for Lumbar Spinal Stenosis: The Lumbar Extension Test Is Not a Predictive Factor

Study Design. A prospective clinical study. Objectives. To investigate the predictive value of the lumbar extension test for outcome after surgical treatment of lumbar spinal stenosis (LSS). Summary of Background Data. Studies have indicated that aggravation of the symptoms from LSS by extension of the lumbar spine has predictive value for the outcome after decompression. The aim of this study was to investigate this theory in a larger group of patients. Methods. One hundred forty-six consecutive patients surgically treated for LSS were included in the study. The clinical condition was recorded before surgery and at 3, 6, 12, and 24 months after surgery using 3 different scoring systems: Swiss Spinal Stenosis Questionnaire, Neurogenic Claudication Outcome Score, and Oswestry Disability Index. The group of patients with preoperative aggravation of the symptoms by the lumbar extension test, (positive extension test), was compared with the group of patients without aggravation by the test, (negative extension test). Results. Before surgery, patients with a positive extension test scored significantly worse on all disability scoring systems than patients with a negative test. However, the extension test itself had no prognostic value for the overall outcome after lumbar decompression. Using regression models with the 2-year Oswestry Disability Index as dependent variable, only before surgery self-reported health and age were found to have prognostic significance. Conclusion. The lumbar extension test has no predictive value for the outcome after surgical treatment of LSS.
The road to excellence: deliberate practice and the development of expertise

The relative contribution of domain‐specific and non‐domain‐specific activities to the development of soccer expertise was examined using a retrospective cross‐sectional design. Elite and sub‐elite players aged between 9 and 18 years of age completed a participation history questionnaire under supervision. Weekly and accumulated hours spent in soccer team practice most consistently discriminated between skill levels across age cohorts. Elite players spent more time in decision‐making activities during team practice, possessed higher levels of motivation and had greater parental support. Maturational indices, time spent in playful activities, sporting diversity and time at which specialization occurred did not differentiate between groups. Engaging in activities deliberately designed to improve performance rather than mere experience within the domain or experience of related activities is likely to lead to elite status.
Intraneural Injection with Low-Current Stimulation During Popliteal Sciatic Nerve Block

BACKGROUND: Prevention of an intraneural injection of a local anesthetic during peripheral nerve blockade is considered important to avoid neurologic injury. However, the needle-nerve relationship during low-current electrical nerve localization is not well understood. METHODS: We postulated that intraneural needletip location is common during low-current stimulation popliteal sciatic nerve blockade. Twenty-four consecutive ASA class I-III patients scheduled for foot or ankle surgery under popliteal sciatic nerve block using a combined ultrasound and nerve stimulator-guided technique were prospectively studied. The end point for needle advancement was predetermined to be either an elicited motor response between 0.2 and 0.5 mA (100 &mgr;s/2 Hz) or an apparent intraneural location of the needletip as seen on ultrasound, whichever came first. The injection occurred at either end points provided the injection pressure was <20 psi. The injection was considered intraneural when injectate resulted in both the swelling and compartmentalization of the nerve within the epineurium. RESULTS: Elicited motor response could be obtained only upon entry of the needle into the intraneural space in 20 patients (83.3%). In the remaining four patients (16.7%), a motor response with a stimulating current of 1.5 mA could not be obtained even after the needle entry into the intraneural space. An injection in the intraneural space occurred in all patients who had motor-evoked response at current 0.2–0.4 mA. All 24 blocks resulted in adequate anesthesia for foot surgery. No patient developed postoperative neurologic dysfunction. CONCLUSION: The absence of motor response to nerve stimulation during popliteal sciatic nerve block does not exclude intraneural needle placement and may lead to additional unnecessary attempts at nerve localization. Additionally, low-current stimulation was associated with a high frequency of intraneural needle placement.
Quantitative Effects of 2,4-Dichlorophenoxyacetic Acid on Growth of Suspension-cultured Acer pseudoplatanus Cells: II. Influence of 2,4-D Metabolism and Intracellular pH on the Control of Cell Division by Intracellular 2,4-D Concentration.

The utilization of 2,4-dichlorophenoxyacetic acid (2,4-D) molecules by Acer pseudoplatanus cells is governed mainly by a glucosylation process. Evidence that 2,4-D glucoside molecules are biologically inactive is presented. 2,3,5-Triiodobenzoic acid (TIBA), by inhibiting 2,4-D glucosylation, has a sparing effect on 2,4-D molecules; thus TIBA treatments increase growth yield (expressed as the ratio of the maximum number of cells produced to the initial concentration of 2,4-D in the culture medium). Significant amounts of intact 2,4-D molecules remain outside and inside the cells when cell division stops at the onset of the stationary phase. This result and the previous demonstration that, at the onset of the stationary phase, 2,4-D is the specific limiting factor of cell division (Leguay JJ, J Guern 1975 Plant Physiol 56: 356-359) suggest that a threshold concentration of auxin is needed for cell division to proceed.The distribution of 2,4-D molecules between the cells and the culture medium is dependent on the population density at the stationary phase. The extracellular 2,4-D concentration at that time is a linear function of the population density whereas intracellular amounts of 2,4-D and 2,4-D metabolites are constant. By using a modified 2-(14)C,-5,5-dimethyloxazolidine-2,4-dione technique, it has been shown that the intracellular pH is markedly lowered as the population density at the plateau is increased. This intracellular pH modification is likely to be responsible for a large modification of the ratio between intracellular and extracellular auxin concentrations.The intracellular auxin concentration reaches a constant value (about 3 x 10(-7)m), independent of population density when cell division stops at the onset of the stationary phase suggesting that it represents the threshold value of the control for cell division.
Hepatitis C virus (HCV) subtype prevalence in Chiang Mai, Thailand, and identification of novel subtypes of HCV major type 6

Subtype analysis of hepatitis C viruses (HCVs) obtained from patients with chronic liver disease in Chiang Mai, Thailand, was performed. Of 46 HCV isolates, 13 (28%) were shown to belong to HCV subtype 3a (HCV-3a), 10 (22%) to belong to HCV-1a, 7 (15%) to belong to HCV-1b, 1 (2%) to belong to HCV-3b, and 1 (2%) to belong to a variant group, as determined from partial nucleotide sequences of the NS5B region of the viral genome. Analysis of 5' untranslated region sequences identified five other isolates (11%) of HCV type 1 and two other isolates (4%) of type 3. Detailed phylogenetic positions for the variant described above and those previously obtained from blood donors and drug addicts in Chiang Mai were determined by a six-parameter neighbor-joining method on the basis of core, E1, and NS5B region sequences. The results revealed that those sequence variants represent novel subtypes of HCV type 6. The HCV type 6 isolates appear to be antigenically different from isolates of HCV types 1 and 2, as determined by a serotyping method that utilizes recombinant peptides corresponding to a portion of the NS4 protein. The significance of subtype analysis around this area is discussed.
The care of corporal punishment: Conceptions of early childhood discipline strategies among parents and grandparents in a poor and urban area in Tanzania

This study investigates conceptions of early childhood discipline strategies discussed in focus groups with parents and grandparents in a poor urban area in Tanzania. A grounded theory analysis suggested a model that included four discipline strategies related to corporal punishment: to beat with care, to treat like an egg, as if beating a snake and the non-care of non-beating. In order to develop strategies to prevent corporal punishment in the home in accordance with the UN recommendation and article 19 in the Convention on the Rights of the Child, the power of caregiving needs further investigation.
Trichomonas vaginalis Infection in a Tertiary Care Vaginitis Center

Background Trichomonas vaginalis infection (TVI) is one of the most common sexually transmitted diseases in the United States. We sought to determine the features of TVI in a referral-based vaginitis center, focusing on diagnosis and treatment of difficult cases. Methods We conducted a retrospective review of all patients with TVI, based on International Classification of Diseases, Ninth Revision codes, seen at the Drexel Vaginitis Center between January 2008 and November 2013. Information collected on each subject included demographics, symptoms, examination findings, diagnostic tests, and treatment regimens. Results Of approximately 4000 new patient visits during our study period, 80 subjects were identified with TVI. Twenty subjects presented with known TVI, with most having clinically resistant infections. Diagnosis was confirmed by saline microscopy in 45%, OSOM rapid test in 40%, and clinical history in the remaining 15%. Treatment regimens varied: 20% received single 2-g dosing of either metronidazole or tinidazole, 50% received high-dose regimens, 20% received therapy with vaginal paromomycin, and 10% underwent desensitization for nitroimidazole allergy. Sixty subjects had newly diagnosed TVI, with 35% diagnosed by saline microscopy, 41.7% by OSOM rapid test, and 23.3% by APTIMA. Treatment regimens for these subjects included single 2-g dosing in 88.3%, high-dose regimen in 8.3%, and other formulations in the remaining 3.4%. In total, 80% of our subjects returned for follow-up; all of whom were cured. Conclusions T. vaginalis infection is a rare condition in a tertiary care vaginitis center and often requires nonstandard treatments. Among those who returned for follow-up, the cure rate was 100%.
A cytological study of the postnatal development of the rabbit oviduct epithelium.

become secretory exhibit the preliminary cytological changes: an increase in the size of the Colgi complex and an increase in the amount of rough endoplasmic reticulum. Initial stages of ciliary development are also seen in some of those cells destined to bear a ciliated border. By 12-20 days after birth, the size of the Colgi complex and the amount of rough endoplasmic reticulum has markedly increased in the secretory cells. In the isthmus, secretory granules can be observed in the Colgi region and also in the apex of the cell. Mature ciliated cells are present at this time. Twenty-four to sixty days after birth, secretory cells containing secretory granules are present in both the ampuila and isthmus of the oviduct. The secretory granules of the ampulla are generally more electron-dense than those of the isthmus. By 90 days after birth, the epithelial cells lining the oviduct appear very similar to those of the adult; the secretory cells are packed with secretory granules, and release of these granules into the tubal lumen is observed.
Dynamically regularized harmony learning of Gaussian mixtures

In this paper, a dynamically regularized harmony learning (DRHL) algorithm is proposed for Gaussian mixture learning with a favourite feature of both adaptive model selection and consistent parameter estimation. Specifically, under the framework of Bayesian Ying-Yang (BYY) harmony learning, we utilize the average Shannon entropy of the posterior probability per sample as a regularization term being controlled by a scale factor to the harmony function on Gaussian mixtures increasing from 0 to 1 dynamically. It is demonstrated by the experiments on both synthetic and real-world datasets that the DRHL algorithm can not only select the correct number of actual Gaussians in the dataset, but also obtain the maximum likelihood (ML) estimators of the parameters in the actual mixture. Moreover, the DRHL algorithm is scalable and can be implemented on a big dataset.
Are serum inflammatory markers age dependent in acute appendicitis?

BACKGROUND Preoperative measurement of body inflammatory agents reduces unnecessary appendectomies by up to 30 percent. A decline in the formation of blood leukocytes and C-reactive protein with aging may hinder the correct diagnosis of appendicitis. STUDY DESIGN White cell count and C-reactive protein were determined before appendectomy in 600 patients aged 0 to 5 years, 6 to 19 years, 20 to 39 years, 40 to 59 years, 60 to 79 years, and older than 80 years. Their records were analyzed. The sensitivity, specificity, diagnostic accuracy, and receiver-operating characteristic curves for C-reactive protein and white cell count to predict appendicitis were calculated separately for each age group. RESULTS The rates of negative explorations and perforations were highest at both extremes of age. In uncomplicated appendicitis, the diagnostic potential of white cell count was better than C-reactive protein in all age groups except infants. The C-reactive protein was elevated similarly throughout human life, but only in those with perforated appendicitis. The receiver-operating characteristic curves confirmed that the performance of white cell count was better than C-reactive protein in the correct diagnosis in every age group except infants and octogenarians. CONCLUSIONS The leukocyte response declines in 0- to 5-year-old children with appendicitis, but the C-reactive protein response is well preserved in all other age groups.