Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhancing Decision Support in Multi User Service Selection

In service-oriented systems, the execution of processes can be supported by composing a variety of different services. In this context, an important research question concerns the selection of the optimal services while taking multiple users and their individual goals into account. Existing multi user service selection approaches focus on restrictions like fixed capacity restrictions of services. However, due to inter-user relations there may also be user requests that refer to other users, like for example that some users may prefer to conduct certain services together. Such Inter-User-Requests (IUR) – have not been addressed in research yet. To address this issue, we propose a novel multi user service selection approach taking into account IUR. We evaluate our approach with respect to correctness and performance. In addition, we examine the practical applicability by means of a real-world example and show that considering IUR in multi user service selection can considerably enhance decision support.
Cooperation between TNF Receptor-Associated Factors 1 and 2 in CD40 Signaling1

TNFR-associated factor 1 (TRAF1) is unique among the TRAF family, lacking most zinc-binding features, and showing marked up-regulation following activation signals. However, the biological roles that TRAF1 plays in immune cell signaling have been elusive, with many reports assigning contradictory roles to TRAF1. The overlapping binding site for TRAFs 1, 2, and 3 on many TNFR superfamily molecules, together with the early lethality of mice deficient in TRAFs 2 and 3, has complicated the quest for a clear understanding of the functions of TRAF1. Using a new method for gene targeting by homologous recombination in somatic cells, we produced and studied signaling by CD40 and its viral oncogenic mimic, latent membrane protein 1 (LMP1) in mouse B cell lines lacking TRAF1, TRAF2, or both TRAFs. Results indicate that TRAFs 1 and 2 cooperate in CD40-mediated activation of the B cell lines, with a dual deficiency leading to a markedly greater loss of function than that of either TRAF alone. In the absence of TRAF1, an increased amount of TRAF2 was recruited to lipid rafts, and subsequently, more robust degradation of TRAF2 and TRAF3 was induced in response to CD40 signaling. In contrast, LMP1 did not require either TRAFs 1 or 2 to induce activation. Taken together, our findings indicate that TRAF1 and TRAF2 cooperate in CD40 but not LMP1 signaling and suggest that cellular levels of TRAF1 may play an important role in modulating the degradation of TRAF2 and TRAF3 in response to signals from the TNFR superfamily.
A mediation analysis of the ATHENA intervention for female athletes: prevention of athletic-enhancing substance use and unhealthy weight loss behaviors.

OBJECTIVE To explain, through mediation analyses, the mechanisms by which ATHENA (Athletes Targeting Healthy Exercise and Nutrition Alternatives), a primary prevention and health promotion intervention designed to deter unhealthy body shaping behaviors among female high school athletes, produced immediate changes in intentions for unhealthy weight loss and steroid/creatine use, and to examine the link to long-term follow-up intentions and behaviors. METHODS In a randomized trial of 1668 athletes, intervention participants completed coach-led peer-facilitated sessions during their sport season. Participants provided pre-test, immediate post-test, and 9-month follow-up assessments. RESULTS ATHENA decreased intentions for steroid/creatine use and intentions for unhealthy weight loss behaviors at post-test. These effects were most strongly mediated by social norms and self-efficacy for healthy eating. Low post-test intentions were maintained 9 months later and predicted subsequent behavior. CONCLUSIONS ATHENA successfully modified mediators that in turn related to athletic-enhancing substance use and unhealthy weight loss practices. Mediation analyses aid in the understanding of health promotion interventions and inform program development.
Algae Grown on Dairy and Municipal Wastewater for Simultaneous Nutrient Removal and Lipid Production for Biofuel Feedstock

Algae grown on wastewater media are a potential source of low-cost lipids for production of liquid biofuels. This study investigated lipid productivity and nutrient removal by green algae grown during treatment of dairy farm and municipal wastewaters supplemented with CO2 . Dairy wastewater was treated outdoors in bench-scale batch cultures. The lipid content of the volatile solids peaked at Day 6, during exponential growth, and declined thereafter. Peak lipid content ranged from 14–29%, depending on wastewater concentration. Maximum lipid productivity also peaked at Day 6 of batch growth, with a volumetric productivity of 17 mg/day/L of reactor and an areal productivity of 2.8 g/ m2 /day , which would be equivalent to 11,000 L/ha/year (1,200 gal/acre/year) if sustained year round. After 12 days, ammonium and orthophosphate removals were 96 and >99% , respectively. Municipal wastewater was treated in semicontinuous indoor cultures with 2–4 day hydraulic residence times (HRTs). Maximum lipid productivity f.
Technology Acceptance by Health Professionals in Canada: An Analysis with a Modified UTAUT Model

Information systems (IS) offer healthcare practitioners a variety of benefits. As such, the acceptance of such technologies by healthcare professionals is an important topic of interest to both practitioners and researchers. IS acceptance has been widely researched in the extant literature, however, studies focusing on perspectives of healthcare professionals are sparsely represented. To add the growing work in this area, we used the unified theory of acceptance and use of technology (UTAUT) with a minor modification to examine the factors influencing IS acceptance among five healthcare professionals in Canada. A research model was developed and tested with data collected in a survey. Analyses of 227 healthcare professionals' data confirmed that their intentions to use IS and usage behaviors were significantly influenced by effort expectancy, social influence, compatibility, and organizational facilitating conditions. Performance expectancy did not yield meaningful interpretations. The study's implications for practice and research are discussed.
Engineering self-organising emergent systems with simulation-based scientific analysis

The goal of engineering self-organising emergent systems is to acquire a macroscopic system behaviour solely from autonomous local activity and interaction. Due to the non-deterministic nature of such systems, it is hard to guarantee that the required macroscopic behaviour is achieved and maintained. Before even considering a self-organising emergent system in an industrial context, e.g. for Automated Guided Vehicle (AGV) transportation systems, such guarantees are needed. An empirical analysis approach is proposed that combines realistic agentbased simulations with existing scientific numerical algorithms for analysing the macroscopic behaviour. The numerical algorithm itself obtains the analysis results on the fly by steering and accelerating the simulation process according to the algorithm’s goal. The approach is feasible, compared to formal proofs, and leads to more reliable and valuable results, compared to mere observation of simulation results. Also, the approach allows to systematically analyse the macroscopic behaviour to acquire macroscopic guarantees and feedback that can be used by an engineering process to iteratively shape a self-organising emergent solution.
Gender Differences in Mathematics and Integrated Science Achievement Among Junior Secondary School Students

Purpose – This study examined gender differences in Mathematics and Integrated Science achievement among the Junior Secondary School students with particular interest on the interaction effect of gender and school type on students’ achievement. Method – The study adopted an ex-post facto research design and generated data from an inventory from the statistics unit, Ministry of Education, Ado Ekiti, Nigeria Public Junior Secondary Schools (JSS). The inventory requested among other things, data on the Junior Secondary School Certifi cate Examinations (JSSCE) in Mathematics and Integrated Science over a two year period. Findings – The study revealed that, signifi cant difference was detected in students’ Science achievement; no signifi cant difference between male and female students in private and public schools; a strong interaction effect were detected between gender of the students, the type of school attended and achievement of students in Mathematics and Integrated Science; the average achievement gap of male and female students irrespective of the school type is statistically signifi cant in both Mathematics and Integrated Science, also, the strength of relationship between the gender of the students and the type of school attended is slightly stronger in Integrated Science than Mathematics. Value – The possible implications for the study is discussed and addressed to the government and other stakeholders in education.
Active Citizenship and Young People: Opportunities, Experiences and Challenges in and beyond School Citizenship Education Longitudinal Study: Fourth Annual Report. Research Report RR732.

The Citizenship Education Longitudinal Study, conducted by the National Foundation for Educational Research (NFER) on behalf of the Department for Education and Skills (DfES), aims to identify measure and evaluate the extent to which effective practice in citizenship education develops in schools. The study began in 2001 and will conclude in 2009. The report sets out the findings from the second longitudinal survey and visits to ten case-study schools.
The role of plant type and salinity in the selection for the denitrifying community structure in the rhizosphere of wetland vegetation.

Coastal wetlands, as transient links from terrestrial to marine environments, are important for nitrogen removal by denitrification. Denitrification strongly depends on both the presence of emergent plants and the denitrifier communities selected by different plant species. In this study, the effects of vegetation and habitat heterogeneity on the community of denitrifying bacteria were investigated in nine coastal wetlands in two preserved areas of Spain. Sampling locations were selected to cover a range of salinity (0.81 to 31.3 mS/cm) and nitrate concentrations (0.1 to 303 μM NO3-), allowing the evaluation of environmental variables that select for denitrifier communities in the rhizosphere of Phragmites sp. , Ruppia sp. , and Paspalum sp. Potential nitrate reduction rates were found to be dependent on the sampling time and plant species and related to the denitrifier community structure, which was assessed by terminal restriction fragment length polymorphism analysis of the functional genes nirS, nirK and nosZ. The results showed that denitrifier community structure was also governed by plant species and salinity, with significant influences of other variables, such as sampling time and location. Ruppia sp. and Phragmites sp. selected for certain communities, whereas this was not the case for Paspalum sp. The plant species effect was strongest on nirK-type denitrifiers, whereas water carbon content was a significant factor defining the structure of the nosZ-harboring community. The differences recognized using the three functional gene markers indicated that different drivers act on denitrifying populations capable of complete denitrification, compared to the overall denitrifier community. This finding may have implications for emissions of the greenhouse gas nitrous oxide.
The Science of Individuality and Tailored M-Health Communication

The era of the science of individuality promises to fully recognize the uniqueness of the individual who needs to be seen and treated with utter respect for his or her individuality. It will not be long until digitizing a person unlocks the cause for what is wrong, creating valuable knowledge that can save a life or markedly improve the quality of life. On the other hand, emerging m-health technologies provide fundamentally different ways of looking at tailored communication technology. As a result, tailored communications research is poised at a crossroads. It needs to both build on and break away from existing frameworks into new territory, realizing the necessary commitment to theory-driven research at basic, methodological, clinical, and applied levels. The chapter envisions tailored m-health communication in the context of the science of individuality, emphasizing the variability, stability, and centrality of the individual.
Uses and limits of empirical data in measuring and modeling human lead exposure.

This paper examines the uses and limits of empirical data in evaluating measurement and modeling approaches to human lead exposure. Empirical data from experiment or observation or both have been used in studies of lead exposure. For example, experimental studies have elucidated and quantified physiologic or biokinetic parameters of lead exposure under controlled conditions. Observation, i.e., epidemiology, has been widely applied to study population exposures to lead. There is growing interest in the use of lead exposure prediction models and their evaluation before use in risk assessment. Empirical studies of lead exposure must be fully understood, especially their limits, before they are applied as "standards" or reference information for evaluation of exposure models, especially the U.S. Environmental Protection Agency's lead biokinetic model that is a focus of this article. Empirical and modeled datasets for lead exposure may not agree due to a) problems with the observational data or b) problems with the model; caution should be exercised before either a model or observational data are rejected. There are at least three sources of discordance in cases where there is lack of agreement: a) empirical data are accurate but the model is flawed; b) the model is valid but reference empirical data are inaccurate; or c) neither empirical data nor model is accurate, and each is inaccurate in different ways. This paper evaluates some of the critical empirical input to biokinetic models, especially lead bioavailability. ImagesFigure 3
Physical activity in patients with venous leg ulcer – between engagement and avoidance. A patient perspective

Objective: To identify and describe the qualitative variations in how physical activity is perceived and understood by individuals with current or previous venous leg ulcer. Design: A qualitative study using semi-structured interviews. Method: Twenty-two individuals aged 60–85 years were interviewed. The interviews were recorded, transcribed verbatim and analysed by three researchers using a phenomenographic research approach. A set of categories of descriptions and their internal relationships were constructed based on the essential features of the variation in patients’ perceptions of physical activity. Results: Four categories of descriptions were identified: (i) ‘self-management’, (ii) ‘instructions and support’, (iii) ‘fear of injury’ and (iv) ‘a wish to stay normal’. The categories could be interpreted by a two-dimensional construct: (1) perception of venous leg ulcer as a chronic or acute condition and (2) engagement or avoidance behaviour toward physical activity. Chronicity and behaviour combined together formed a 2 × 2 square housing the four qualitatively different categories. Irrespective of category, the participants reported that information given by caregivers regarding leg ulcer and physical activity was insufficient or contradictory. Written information or exercise programmes were not obtained regularly and not at all in primary care. Conclusion: A dichotomous view emerged from participants’ experiences of physical activity based on (1) perception of venous leg ulcer as a chronic or acute condition and (2) engagement or avoidance behaviour toward physical activity.
A Prospective Test of the Hopelessness Theory of Depression in Children

Providing a developmental extension of the cognitive theories of depression, researchers and theorists (e.g., Cole & Turner, 1993; Rose & Abramson, 1992) have suggested that during early to middle childhood, attributional styles may mediate rather than moderate the association between negative life events and the development of depression. Within the context of the hopelessness theory of depression (e.g., Abramson, Metalsky, & Alloy, 1989), we tested this hypothesis in a 6-month longitudinal study of 4th- and 5th-grade children. Using path analysis, we found support for the mediating role of attributional styles among both 4th and 5th graders. Supporting recent refinements in the hopelessness theory, the best fitting mediation model was one in which depressive symptoms exhibited reciprocal relations with the other variables. Specifically, attributional styles partially mediated the link between verbal victimization and residual change in depressive symptoms. In addition, initial depressive symptoms predicted negative changes in children's attributional styles and increases in verbal victimization across the follow-up. Contrary to our hypothesis, we also found support for the moderating role of attributional styles, although this was significant only among 5th graders.
Temporal Contrast Adaptation in Salamander Bipolar Cells

This work investigates how the light responses of salamander bipolar cells adapt to changes in temporal contrast: changes in the depth of the temporal fluctuations in light intensity about the mean. Contrast affected the sensitivity of bipolar cells but not of photoreceptors or horizontal cells, suggesting that adaptation occurred in signal transfer from photoreceptors to bipolars. This suggestion was confirmed by recording from photoreceptor–bipolar pairs and observing a direct dependence of the gain of signal transfer on the contrast of the light input. After an increase in contrast, the onset of adaptation in the bipolar cell had a time constant of 1–2 sec, similar to a fast component of contrast adaptation in the light responses of retinal ganglion cells (Kim and Rieke, 2001). Contrast adaptation was mediated by processes in the dendrites of both on andoff bipolars. The functional properties of adaptation differed for the two bipolar types, however, with contrast having a much more pronounced effect on the kinetics of the responses ofoff cells than on cells.
Generating Robot Gaze on the Basis of Participation Roles and Dominance Estimation in Multiparty Interaction

Gaze is an important nonverbal feedback signal in multiparty face-to-face conversations. It is well known that gaze behaviors differ depending on participation role: speaker, addressee, or side participant. In this study, we focus on dominance as another factor that affects gaze. First, we conducted an empirical study and analyzed its results that showed how gaze behaviors are affected by both dominance and participation roles. Then, using speech and gaze information that was statistically significant for distinguishing the more dominant and less dominant person in an empirical study, we established a regression-based model for estimating conversational dominance. On the basis of the model, we implemented a dominance estimation mechanism that processes online speech and head direction data. Then we applied our findings to human-robot interaction. To design robot gaze behaviors, we analyzed gaze transitions with respect to participation roles and dominance and implemented gaze-transition models as robot gaze behavior generation rules. Finally, we evaluated a humanoid robot that has dominance estimation functionality and determines its gaze based on the gaze models, and we found that dominant participants had a better impression of less dominant robot gaze behaviors. This suggests that a robot using our gaze models was preferred to a robot that was simply looking at the speaker. We have demonstrated the importance of considering dominance in human-robot multiparty interaction.
The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene

Mutation in the clarin-1 gene (Clrn1) results in loss of hearing and vision in humans (Usher syndrome III), but the role of clarin-1 in the sensory hair cells is unknown. Clarin-1 is predicted to be a four transmembrane domain protein similar to members of the tetraspanin family. Mice carrying null mutation in the clarin-1 gene (Clrn1−/−) show loss of hair cell function and a possible defect in ribbon synapse. We investigated the role of clarin-1 using various in vitro and in vivo approaches. We show by immunohistochemistry and patch-clamp recordings of Ca2+ currents and membrane capacitance from inner hair cells that clarin-1 is not essential for formation or function of ribbon synapse. However, reduced cochlear microphonic potentials, FM1-43 [N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl) pyridinium dibromide] loading, and transduction currents pointed to diminished cochlear hair bundle function in Clrn1−/− mice. Electron microscopy of cochlear hair cells revealed loss of some tall stereocilia and gaps in the v-shaped bundle, although tip links and staircase arrangement of stereocilia were not primarily affected by Clrn1−/− mutation. Human clarin-1 protein expressed in transfected mouse cochlear hair cells localized to the bundle; however, the pathogenic variant p.N48K failed to localize to the bundle. The mouse model generated to study the in vivo consequence of p.N48K in clarin-1 (Clrn1N48K) supports our in vitro and Clrn1−/− mouse data and the conclusion that CLRN1 is an essential hair bundle protein. Furthermore, the ear phenotype in the Clrn1N48K mouse suggests that it is a valuable model for ear disease in CLRN1N48K, the most prevalent Usher syndrome III mutation in North America.
Working memory resources in children: stability and relation to subsequent academic skills

Abstract This study aimed to investigate the extent to which WM measured in kindergarten predicts WM measured in second grade (stability of individual WM progress) and the extent to which WM measured at kindergarten predicts academic performance at second grade (N = 94). The results showed that WM skills significantly increase during the time span from Finnish kindergarten to second grade. Verbal (VWM) and visuospatial WM (VSWM) resources seem to develop quite independently, whereas individual progress showed some stability. WM resources measured just before the start of formal school predicted later academic performance and VWM acted as more powerful predictor than VSWM resources. The results have two important educational implications: first, an individual or group-based intervention designed to enhance children’s WM skills would be most important even before the start of school, and second, poor WM skills should be addressed when planning the learning environment beginning in kindergarten.