Miracle-dz/UniFAR-FTUs huggingface dataset:
A class of time-frequency product optimized biorthogonal wavelet filter banks

The time-frequency product of any function in L2 (R) is bounded by the uncertainty principle. This paper presents a method to design linear phase biorthogonal filter banks with the time-frequency localization as the optimality criterion. The design philosophy is to optimize the time-frequency product of the iterated wavelet, after fixing the number of vanishing moments of the analysis and synthesis lowpass filters, by adjusting a single parameter.
HISTOPATHOLOGY OF SOME DISEASED FISHES

A study on the histopathology of some diseased fishes was carried out during the period from July 2005 to June 2006 in the Institute of Biological Sciences, University of Rajshahi, Rajshahi. Symptoms of diseases of different fish species showed variation among the species and its distribution. The parasites were first found to settled on the body surface and tip of the gills of fishes and attach themselves on the surface by their powerful sucking devices. From the histopathological observations it appeared that gills and body surface were the main infested areas and gill filaments were damaged by the parasites. The histochemical studies showed that the disease caused extensive damages to the blood elements by rupturing blood capillaries, causing necrosis, coagulation and haemorrhage. Key words: Histopathology; symptoms; diseased fish DOI: 10.3329/jles.v2i2. 7497 J. Life Earth Sci., Vol. 2(2) 47-50, 2007
Impact of Low Back Pain Clinical Trials Measured by the Altmetric Score: Cross-Sectional Study

Background There is interest from authors and publishers in sharing the results of their studies over the Internet in order to increase their readership. In this way, articles tend to be discussed and the impact of these articles tends to be increased. In order to measure this type of impact, a new score (named Altmetric) was created. Altmetric aims to understand the individual impact of each article through the attention attracted online. Objective The primary objective of this study was to analyze potential factors related with the publishing journal and the publishing trial that could be associated with Altmetric scores on a random sample of low back pain randomized controlled trials (RCTs). The secondary objective of this study was to describe the characteristics of these trials and their Altmetric scores. Methods We searched for all low back pain RCTs indexed on the Physiotherapy Evidence Database (PEDro; www.pedro.org.au) published between 2010 and 2015. A total of 200 articles were randomly selected, and we extracted data related to the publishing trial, the publishing journal, methodological quality of the trials (measured by the 0-10 item PEDro scale), and total and individual scores of Altmetric mentioned and Altmetric reader. The study was a cross-sectional study, and multivariate regression models and descriptive statistics were used. Results A total of four variables were associated with Altmetric mentioned score: impact factor (β-coefficient=3.4 points), number of years since publication (β-coefficient=–4.9 points), number of citations divided by years since publication (β-coefficient=5.2 points), and descriptive title (β-coefficient=–29.4 points). Only one independent variable was associated with Altmetric reader score: number of citations divided by years since publication (β-coefficient=10.1 points, 95% CI 7.74-12.46). We also found that the majority of articles were published in English, with a descriptive title, and published in open access journals endorsing the Consolidated Standards of Reporting Trials (CONSORT) statement. Conclusions Researchers should preferably select high impact factor journals for submission and use declarative or interrogative titles, as these factors are likely to increase the visibility of their studies in social media.
Predisposing factors for chemotherapy-induced nephrotoxicity in patients with advanced esophageal cancer who received combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil

Abstract Background and Objectives We retrospectively studied the predisposing factors for nephrotoxicity in the patients with advanced esophageal squamous-cell carcinoma who received combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF therapy). Methods Between January 2010 and March 2014, 41 patients with Stage IB to III esophageal squamous-cell carcinoma received the DCF therapy (docetaxel 70-75 mg/m2, day 1; cisplatin 70-75 mg/m2, day 1; 5-fluorouracil 750 mg/m2, days 1-5) in our hospital. Renal dysfunction was defined as a creatinine clearance (Ccr) of less than 60 mL/min. Predictors of nephrotoxicity were identified through logistic-regression analysis. Results Nephrotoxicity developed in 20 patients and did not develop in 21 patients. Nephrotoxicity developed during the first course of DCF therapy in 16 patients, the second course in 3 patients, and the third course in 1 patient. The dose of DCF therapy was decreased in 8 patients with nephrotoxicity and 7 patients without nephrotoxicity. Multivariate analysis showed that a low Ccr level immediately before DCF therapy was an independent risk factor for the development of nephrotoxicity (odds ratio, 0.932; 95% confidence interval, 0.876 to 0.992; P = 0.027). On receiver operating characteristic curve analysis, the optimal cutoff value of Ccr for the development of nephrotoxicity was 75.8 mL/min. The 2-year overall survival rate was 84.2% in patients with nephrotoxicity and 90.0% in patients without nephrotoxicity (P = 0.635). Conclusions Low Ccr levels immediately before DCF therapy are a risk factor for the development of nephrotoxicity. Patients should therefore be carefully monitored.
Ambiguity in the Dural Tail Sign on MRI

Background: Meningiomas give rise to the dural tail sign (DTS) on contrast-enhanced magnetic resonance imaging (CEMRI). The presence of DTS does not always qualify for a meningioma, as it is seen in only 60-72% of cases. This sign has been described in various other lesions like lymphomas, metastasis, hemangiopericytomas, schwannomas and very rarely glioblastoma multiforme (GBM). The characteristics of dural-based GBMs are discussed here, as only eleven such cases are reported in the literature till date. Here we discuss the unique features of this rare presentation. Case Description: A 17-year-old male presented to the emergency department (ED) with, complaints of headache, recurrent vomiting, vision loss in right eye and altered sensorium. On examination patient was drowsy with right hemiparesis, secondary optic atrophy in the right eye and papilledema in the left eye. MRI brain showed, heterogeneous predominantly solid cystic lesion with central hypo-intense core suggestive of necrosis with heterogeneous enhancement and a positive DTS. Patient underwent emergency left parasagittal parieto-occipital craniotomy and gross total tumor excision including the involved dura and the falx. On opening the dura, tumor was surfacing, invading the superior sagittal sinus and the falx, greyish, soft to firm in consistency with central necrosis and highly vascular suggesting a high-grade lesion. Postoperative computed tomography (CT) of the brain showed evidence of gross total tumor (GTR) excision. The postoperative course of the patient was uneventful. Histopathological analysis revealed GBM with PNET like components. The dura as well as the falx were involved by the tumor. Conclusion: GBMs can arise in typical locations along with DTS mimicking meningiomas. Excision of the involved dura and the falx becomes important in this scenario, so as to achieve GTR. Hence high index of suspicion preoperatively aided by Magnetic Resonance Imaging (MRS) can help distinguish GBMs from meningioma, thereby impacting upon the prognosis.
Mean-Reverting Portfolio With Budget Constraint

This paper considers the mean-reverting portfolio (MRP) design problem arising from statistical arbitrage (a.k.a. pairs trading) in the financial markets. It aims at designing a portfolio of underlying assets by optimizing the mean reversion strength of the portfolio, while taking into consideration the portfolio variance and an investment budget constraint. Several specific design problems are considered based on different mean reversion criteria. Efficient algorithms are proposed to solve the problems. Numerical results on both synthetic and market data show that the proposed MRP design methods can generate consistent profits and outperform the traditional design methods and the benchmark methods in the literature.
Dietary dopamine depletion blunts reward network sensitivity to face trustworthiness

Research demonstrating responsiveness of the neural reward network to face trustworthiness has not assessed whether the effects are mediated by dopaminergic function. We filled this gap in the literature by investigating whether dietary dopamine depletion would blunt the sensitivity of neural activation to faces varying in trustworthiness across reward regions as well as the sensitivity of behavioral responses to those faces. As prolactin release is negatively regulated by dopamine, peripheral prolactin levels confirmed the efficacy of our manipulation. The dopamine depletion manipulation moderated neural activation to face trustworthiness in the amygdala, medial orbital frontal cortex, and ventral medial prefrontal cortex. Control participants (n=20) showed nonlinear and linear neural activation to face trustworthiness in the amygdala and ventral medial prefrontal cortex, and nonlinear activation in the medial orbital frontal cortex, while depleted participants (n=20) showed only a linear effect in the amygdala. Controls also showed stronger amygdala activation to high trustworthy faces than depleted participants. In contrast to effects on neural activation, dopamine depletion did not blunt the sensitivity of behavioral ratings. While this is the first study to demonstrate that dopamine depletion blunts the sensitivity of the neural reward system to social stimuli, namely faces varying in trustworthiness, future research should investigate behavioral measures that may be more responsive to dopaminergic effects than face ratings. Such research would shed further light on the possibility that individual differences in dopaminergic function that were simulated by our manipulation influence social interactions with people who vary in facial trustworthiness.
Mitigating exotic impacts: restoring deer mouse populations elevated by an exotic food subsidy.

The threat posed by exotic organisms to native systems has led to extensive research on exotic invaders, yet management of invasives has progressed relatively slowly. This is partly due to poor understanding of how exotic species management influences native organisms. To address this shortfall, we experimentally evaluated the efficacy of an invasives management tool for restoring native deer mouse (Peromyscus maniculatus) populations elevated by exotic species. The exotic insects, Urophora spp. , were introduced in North America for biological control of the Eurasian invader, spotted knapweed (Centaurea maculosa), but instead of controlling C. maculosa, Urophora have become an important food resource that doubles P. maniculatus populations, with substantial indirect effects on other organisms. We hypothesized that herbicide suppression of Urophora's host plant would reduce the Urophora food resource and restore P. maniculatus populations to natural levels. Prior to treatment, mouse populations did not differ between controls and treatments, but following treatment, P. maniculatus were half as abundant where treatment reduced Urophora. Peromyscus maniculatus is insensitive to direct herbicide effects, and herbicide-induced habitat changes could not explain the P. maniculatus response. Treatment-induced reductions of the Urophora food resource offered the most parsimonious explanation for the mouse response: Multistate mark-recapture models indicated that P. maniculatus survival declined where Urophora were removed, and survival rates were more correlated with variation in population size than movement rates. Other demographic and reproductive parameters (sex ratios, reproductive status, pregnancy rates, and juvenile recruitment) were unaffected by treatment. These results suggest the Urophora biocontrol elevated P. maniculatus survival, and the herbicide treatment restored mouse populations by removing the exotic food and reducing survival. This work illustrates the importance of mechanistic understandings of community and population ecology for improving invasive species management.
Celiac Disease 30 Years After Diagnosis: Struggling With Gluten-free Adherence or Gaining Gluten Tolerance?

Objectives: Studies investigating patients with coeliac disease (CD) on very long-term follow-up are limited. We aimed to evaluate the characteristics of patients with CD diagnosed more than 30 years ago. Methods: Clinical, histologic, genetic, and demographic data of patients with CD diagnosis made before 1985 were collected and their standardised mortality ratio calculated. According to the gluten-free diet (GFD) status, CD patients were divided into 3 groups and a specific questionnaire on GFD awareness and gluten-free products was administered to patients and caregivers. Results: A total of 337 CD patients were included in the study. The standardised mortality ratio was 0.37 (confidence interval 0.10 to 0.94) compared with a matched population. A total of 197 patients were grouped according to GFD compliance, with 35 CD patients reporting chronic voluntary gluten ingestion. No significant differences were found between groups regarding family history of CD, symptoms and histology at diagnosis, autoimmune disorders. Follow-up histology was performed in 63 patients. Twenty patients had normal histology on gluten-containing diet (GCD). Questionnaire scores were lower in patients on GCD. Caregivers scores were not correlated with patients’ gluten consumption. Conclusions: Although poor adherence to GFD is the major predictor of persistence of mucosal lesions at follow-up histology, a proportion of patients did not show a relapse of villous atrophy in spite chronic voluntary gluten ingestion, nor increase in mortality. Moreover, GFD knowledge and adherence could be partly lost during the transition between childhood and adulthood.
Targeted Imaging of Tumor-Associated Macrophages by Cyanine 7-Labeled Mannose in Xenograft Tumors

Mannose receptor is considered as a hallmark of M2-oriented tumor-associated macrophages (TAMs), but its utility in TAMs was rarely reported. Therefore, deoxymannose (DM), a high-affinity ligand of mannose receptor, was labeled with near-infrared dye cyanine 7 (Cy7), and its feasibility of targeted imaging on TAMs was evaluated in vitro and in vivo. The Cy7-DM was synthesized, and its binding affinity with induced TAMs in vitro, whole-body imaging in xenograft tumor mouse model in vivo, and the cellular localization in dissected tissues were evaluated. We demonstrated a high uptake of Cy7-DM by induced M2 macrophages and TAMs in tumor tissues. In vivo near-infrared live imaging visualized abundant TAMs in tumor lesions instead of inflammatory sites by Cy7-DM imaging, and the quantity of Cy7-DM signals in tumors was significantly higher than that shown in inflammatory sites from 1 to 8 hours of imaging. Our results suggest that mannose could rapidly and specifically target TAMs and is a promising candidate for targeted diagnosis of tumor with rich TAMs.
[Correlation of tomographic findings with pulmonary function parameters in nonsmoking patients with idiopathic pulmonary fibrosis].

OBJECTIVE To correlate tomographic findings with pulmonary function parameters in patients with idiopathic pulmonary fibrosis (IPF). METHODS A cross-sectional study was carried out, in which 30 nonsmoking patients with IPF were evaluated. Using a semiquantitative scoring system, the following high-resolution computerized tomography (HRCT) findings were quantified: total interstitial disease (TID), reticular abnormality/honeycombing, and ground-glass opacity (GGO). The functional variables were measured by spirometry, forced oscillation technique (FOT), helium dilution method, as well as the single-breath method of measuring diffusion capacity of the lung for carbon monoxide (DLCO). RESULTS Of the 30 patients studied, 18 were female, and 12 were male, with a mean age of 70.9 years. We found that TID and reticular abnormality and honeycombing correlated significantly (negative correlations) with the measurements of forced vital capacity (FVC), total lung capacity (TLC), DLCO, and dynamic respiratory compliance were found, as well as that GGO correlated significantly (and positively) with residual volume/TLC. The ratio of forced expiratory flow between 25 and 75% of FVC to FVC (FEF(25-75%)/FVC) correlated positively with TID, reticular abnormality/honeycombing, and GGO. CONCLUSION In IPF patients, the measurements of volume, diffusion, and dynamic compliance are the physiological variables which best reflect the extent of the interstitial disease on HRCT scans.
Exploring the effect of chronotype on hippocampal volume and shape: A combined approach

ABSTRACT Current evidence suggests that acute depression is associated with reduced total hippocampal volume and regional atrophy. Here, using structural magnetic resonance imaging, we assayed linear effects of chronotype on total hippocampal volume and morphology. Later chronotype was associated with localised atrophy in the subiculum region of the right hippocampus in the absence of changes in total volume. The hippocampus forms a key node in a network of brain regions implicated in emotional regulation and alterations in the structure of this region may underpin, in part, the increased vulnerability for depression in late chronotype individuals.
Bringing Cartoons to Life: Towards Improved Cartoon Face Detection and Recognition Systems

Given the recent deep learning advancements in face detection and recognition techniques for human faces, this paper answers the question "how well would they work for cartoons'? " - a domain that remains largely unexplored until recently, mainly due to the unavailability of large scale datasets and the failure of traditional methods on these. Our work studies and extends multiple frameworks for the aforementioned tasks. For face detection, we incorporate the Multi-task Cascaded Convolutional Network (MTCNN) architecture and contrast it with conventional methods. For face recognition, our two-fold contributions include: (i) an inductive transfer learning approach combining the feature learning capability of the Inception v3 network and the feature recognizing capability of Support Vector Machines (SVMs), (ii) a proposed Hybrid Convolutional Neural Network (HCNN) framework trained over a fusion of pixel values and 15 manually located facial keypoints. All the methods are evaluated on the Cartoon Faces in the Wild (IIIT-CFW) database. We demonstrate that the HCNN model offers stability superior to that of Inception+SVM over larger input variations, and explore the plausible architectural principles. We show that the Inception+SVM model establishes a state-of-the-art F1 score on the task of gender recognition of cartoon faces. Further, we introduce a small database hosting location coordinates of 15 points on the cartoon faces belonging to 50 public figures of the IIIT-CFW database.
A review of aflatoxin: occurrence, prevention, and gaps in both food and feed safety

Aflatoxins are one of many natural occurring mycotoxins that are found in soils, foods, humans, and animals. Derived from the Aspergillus flavus fungus, the toxigenic strains of aflatoxins are among the most harmful mycotoxins. Aflatoxins are found in the soil as well as in grains, nuts, dairy products, tea, spices and cocoa, as well as animal and fish feeds [1]. Aflatoxins are especially problematic in hot, dry climates (+/30 to 40 degrees latitude) and their prevalence is exacerbated by drought, pests, delayed harvest, insufficient drying and poor post-harvest handling. Exposure to foods contaminated with high levels of aflatoxins can cause immediate death to humans and animals. Chronic high levels lead to a gradual deterioration of health through liver damage and immune suppression. Linkages with child stunting are suspected but not proven. Malaria and HIV/AIDS may also be affected by aflatoxin levels, though to date the evidence is inconclusive.
Association between risk behaviors and adiposity indicators in adolescents from Southern Brazil

The aim of this study was to analyze the association between risk behaviors and adiposity indicators in adolescents and to discuss some methodological aspects related to this relationship. We evaluated 1,321 adolescents (55.2% female) aged 10–16 years. Relative body fat (%fat) by measurement of triceps and subscapular skinfold thickness and waist circumference (WC) were used as total and central adiposity indicators, respectively. Physical inactivity, time spent in front of the TV, the consumption of soda and/or chocolate, alcohol, and tobacco smoking were analyzed as risk behaviors. Information about the socioeconomic status (categorized into three levels) and nutritional status of the mother (overweight or normal weight) were used as adjustment factors in the analyses of prevalence ratio (PR) of the outcomes and their associated 95% confidence intervals (95% CI). The chi-square test and Poisson regression were used for statistical analyses. Low associations were found between risk behaviors and adiposity indicators. Tobacco smoking was the most positively correlated behavior with adiposity in girls (%fat: PR = 1.61; 95% CI = 1.04–2.47; WC: PR = 1.90; 95% CI = 1.17–3.08) and in adolescents whose mothers were normal weight (%fat: PR = 2.31; 95% CI = 1.33–4.03; WC: PR: 2.31; CI: 1.19–4.46). Additionally, as an important methodological issue, we highlighted the assessment of risk behaviors in adolescents as crucial to producing more robust evidence on the subject. Of the investigated behaviors, we concluded that tobacco smoking is the behavior most associated with adiposity indicators.
Urbanisation and the incidence of eating disorders

urbanisation and a numberofmental disorders iswell established. Schizophrenia, psychosis and depression areknownto occurmore frequently in urban areas.In our primarycare-based studyof eatingdisorders, the incidence of bulimia nervosa showed a dose^response relationwith degree of urbanisation and was five timeshigher in cities than inrural areas.Remarkably, anorexia nervosa showedno associationwithurbanisation. We conclude thaturban life is a potential environmentalrisk factor for bulimia nervosa butnot for anorexia nervosa. These findingsprovide a promisingavenue for further research into the aetiologyof eatingdisorders.
A Survey on OpenFlow Technologies

SUMMARY The paper presents a survey on OpenFlow related technologies that have been proposed as a means for researchers, network service creators, and others to easily design, test, and deploy their innovative ideas in experimental or production networks to accelerate research activities on network technologies. Rather than having programmability within each network node, separated OpenFlow controllers provide network control through pluggable software modules; thus, it is easy to develop new network control functions in executable form and test them in production networks. The emergence of OpenFlow has started various research activities. The paper surveys these activities and their results.