Miracle-dz/UniFAR-FTUs huggingface dataset:
Perception and reality: a national evaluation of social norms marketing interventions to reduce college students' heavy alcohol use.

OBJECTIVE To evaluate a widely used intervention to reduce college student alcohol use, we studied student drinking patterns at colleges that employed social norms marketing programs and those that did not. METHOD We examined responses of students in the Harvard School of Public Health College Alcohol Study (CAS) 1997, 1999 and 2001 data sets at 37 colleges that employed social norms marketing programs and at 61 that did not. Information about the students' drinking behavior and their familiarity with social norms marketing messages at their schools was analyzed, as were college administrators' reports about the implementation of social norms marketing campaigns. Schools were grouped on the basis of student reports of exposure to programmatic materials. Trend analyses were conducted on seven standard measures of alcohol consumption, including annual and 30-day use, frequency, usual quantity and volume consumed, heavy episodic use, and drunkenness. RESULTS Almost half of the CAS colleges sampled adopted social norms programs. Those that did were more likely to have large enrollments, not to be religiously affiliated and to have high rates of alcohol use. No decreases were noted in any of the seven measures of alcohol use at schools with social norms programs, even when student exposure and length of program existence were considered. Increases in measures of monthly alcohol use and total volume consumed, however, were observed at schools employing social norms programs. CONCLUSIONS This study does not provide evidence to support the effectiveness of social norms marketing programs, as currently utilized, in reducing alcohol use among college students.
The Gender Gap in Student Attitudes Toward Sexist/Nonsexist Language: Implications for Sport Management Education

This paper discusses three studies on changing people's attitudes toward sexist/nonsexist language. In Study 1, sport management students (N= 164) were asked how to persuade others to use nonsexist language. Many suggested education. Study 2 participants (N = 201) were asked if they had ever discussed sexist language in instructional settings. Analysis of their attitudes revealed an interaction between gender and instruction. Study 3 (N = 248) tested the effects of 3 types of instruction on student attitudes about sexist/nonsexist language. After a 50-minute intervention, Study 3 participants were generally undecided about sexist/nonsexist language, and their attitudes did not differ across instructional strategies (p > .01). In all conditions, males were significantly less receptive to nonsexist language than females (p < .01). This “gender gap” was magnified by a combination of direct and indirect instruction. Until more is known, the authors propose (a) modeling and (b) instruction grounded in empathy .
Purified IgG from seropositive and seronegative patients with myasthenia gravis reversibly blocks currents through nicotinic acetylcholine receptor channels

The mechanism of block of nicotinic acetylcholine receptor (nAChR) channels by purified antibodies from patients with myasthenia gravis (MG) was investigated by using an ultrafast system for solution exchange at outside‐out patches. IgG of MG patients and controls was purified by using protein A–Sepharose columns. Probes from 9 seropositive MG patients and 3 seronegative MG patients were tested. As a preparation, cultured mouse myotubes expressing the embryonic‐type nAChR channels were used. Twenty‐millisecond pulses of 1.0 mM ACh were applied repetitively to outside‐out patches. Outside‐out patches were preexposed with IgG in concentrations between 0.1 and 200 mg/L during application of ACh pulses. The peak current amplitude was reduced to values between 6% and 71% of control for the 9 seropositive and 3 seronegative MG patients. The block was concentration dependent and fully reversible after washout of antibodies. Incubation with IgG from different control patients did not reduce the peak current amplitude. In addition, our findings with purified IgG from seronegative MG patients support the idea of the immunopathogenesis of this disorder and may allow the development of a diagnostic test for seronegative MG patients.
Thickness of Extraocular Muscle and Orbital Fat in MRI Predicts Response to Glucocorticoid Therapy in Graves' Ophthalmopathy

33 patients with active, moderate-severe Graves' ophthalmopathy (GO) received 4.5 g methylprednisolone for 12 weeks and were divided by efficacy into two groups (responsive and unresponsive). All patients and 10 controls underwent orbital MRI examination at baseline. No significant difference was seen in baseline clinical characteristics between the two GO groups. The values of exophthalmos were higher in both GO groups than in the control and were higher in the responsive group versus the unresponsive group. Compared to the unresponsive group, the responsive group had a thicker inferior rectus as well as thinner orbital fat. The inferior rectus/fat ratio was significantly higher in the responsive group versus the unresponsive group. Multivariate logistic regression analysis showed that the exophthalmos value and inferior rectus/fat ratio were significantly associated with the response to glucocorticoid (GC). ROC analysis revealed that the cut-off points of the inferior rectus/fat ratio combined with the exophthalmos value to indicate efficacy were 1.42 and 20.78. For moderate-severe GO patients with CAS > 3, the combined inferior rectus/fat ratio and exophthalmos value in MRI may be a valuable indicator to predict the response to GC therapy.
Bystander Intervention, Bullying, and Victimization: A Multilevel Analysis of New Zealand High Schools

This study examines the association between schools and student bullying behaviors and victimization among a nationally representative sample (N = 9,107) of New Zealand high school students. In particular, the study sought to explore the role of characteristics of schools and school culture with respect to bystander behavior, while controlling for individual student factors related to victimization and bullying behaviors. Results indicated that a total of 6% of students report being bullied weekly or more often and 5% of students reported bullying other students at least weekly. Results of multilevel analyses suggested that schools characterized by students taking action to stop bullying were associated with less victimization and less reported bullying among students. In contrast, in schools where students reported teachers take action to stop bullying, there was no decline in victimization or bullying. Overall, these findings support whole-school approaches that aid students to take action to stop bullying.
Threading a needle: Kazakhstan between civic and ethno-nationalist state-building

This paper examines the state-building project in Kazakhstan since independence in 1991. It argues that both civic and ethno-nationalistic tendencies in state-building can be identified but that it is not any particular trajectory of nationalism in Kazakhstan that is of significance so much as the tensions between two very different trajectories. We argue that, at least to date, the government has succeeded in managing these tensions quite effectively both at the policy level and in its relations with different ethnic groups and neighbouring states. Whether Kazakhstan can continue to manage these tensions in the post-Nazarbayev era is one of the most significant questions facing the country.
Attractiveness of First Names and Academic Achievement

Abstract This archival study was conducted to examine the association of the stereotypical attractiveness of a person's first name with his or her academic performance. Records of 68 students who had completed the 2nd year of a psychology degree at a British metropolitan university were obtained, and their first names were rated for attractiveness. The actual examination and assessed course-work grades for individuals with unattractive names were compared with those of persons whose names were evaluated as average or attractive. Results indicated that individuals with unattractive names performed significantly better than individuals with more attractive names (p = .05), regardless of mode of assessment. The results are interpreted as evidence of the potentially positive impact of evaluatively negative name stereotypes on academic achievement in a natural situation, and as evidence that these stereotypes are internalized.
A Quality Assurance Program for Human Immunodeficiency Virus Seropositivity Screening of Dried-Blood Spot Specimens

Epidemiologic projects have been implemented for using dried-blood spot (DBS) specimens routinely collected on filter paper from neonates as a seroepidemiologic resource to monitor seroprevalence of human immunodeficiency virus (HIV) among childbearing women. To ensure the quality of the data base produced from the national and other epidemiologic surveys, a quality assurance program was developed to interact with all the neonatal screening laboratories. The focus of the Centers for Disease Control's quality assurance program for HIV seropositivity testing of neonatal blood specimens is to maintain a national program to produce, certify, and provide external quality control materials as DBSs on filter paper, to monitor the filter paper matrix, to operate an external performance surveillance program, and to provide other special and consultative services. The dried-blood control and surveillance materials are certified by rigorous testing for accuracy, stability, and homogeneity. Preliminary results from the first performance evaluation of screening laboratories indicated excellent performance. [Infect Control Hosp Epidemiol 1989; 10(1):8-13. ]
Population Inequality: The Case of Repeat Crime Victimization

This paper employs data from the 2000 British Crime Survey for England and Wales to discuss ways of illustrating the degree of inequality in the distribution of crime victimization. In particular, Lorenz curves are presented for major crime categories, i.e. property, personal and vehicle crime, and their components are presented. They are fitted both nationally (Le. to victimized and non-victimized people) and amongst victims. Crime Lorenz curves over victims illustrate repeat victimization. Additional repeat victimization statistics, such as concentration, the percentage of repeat crimes and the percentage of repeat victims, are also shown. Threats and assaults are the most recurring crimes, whereas theft of vehicles shows low rates of repetition within a year.
A hypergraph-based learning algorithm for classifying gene expression and arrayCGH data with prior knowledge

MOTIVATION Incorporating biological prior knowledge into predictive models is a challenging data integration problem in analyzing high-dimensional genomic data. We introduce a hypergraph-based semi-supervised learning algorithm called HyperPrior to classify gene expression and array-based comparative genomic hybridization (arrayCGH) data using biological knowledge as constraints on graph-based learning. HyperPrior is a robust two-step iterative method that alternatively finds the optimal labeling of the samples and the optimal weighting of the features, guided by constraints encoding prior knowledge. The prior knowledge for analyzing gene expression data is that cancer-related genes tend to interact with each other in a protein-protein interaction network. Similarly, the prior knowledge for analyzing arrayCGH data is that probes that are spatially nearby in their layout along the chromosomes tend to be involved in the same amplification or deletion event. Based on the prior knowledge, HyperPrior imposes a consistent weighting of the correlated genomic features in graph-based learning. RESULTS We applied HyperPrior to test two arrayCGH datasets and two gene expression datasets for both cancer classification and biomarker identification. On all the datasets, HyperPrior achieved competitive classification performance, compared with SVMs and the other baselines utilizing the same prior knowledge. HyperPrior also identified several discriminative regions on chromosomes and discriminative subnetworks in the PPI, both of which contain cancer-related genomic elements. Our results suggest that HyperPrior is promising in utilizing biological prior knowledge to achieve better classification performance and more biologically interpretable findings in gene expression and arrayCGH data. AVAILABILITY http://compbio.cs.umn.edu/HyperPrior CONTACT kuang@cs.umn.edu SUPPLEMENTARY INFORMATION Supplementary data are available at bioinformatics online.
Experiential Learning in Social Science Theory: An investigation of the relationship between student enjoyment and learning

This paper provides an analysis of student experiences of an approach to teaching theory that integrates the teaching of theory and data analysis. The argument that supports this approach is that theory is most effectively taught by using empirical data in order to generate and test propositions and hypotheses, thereby emphasising the dialectic relationship between theory and data through experiential learning. Bachelor of Commerce students in two second-year substantive organisational theory subjects were introduced to this method of learning at a large, multi-campus Australian university. In this paper, we present a model that posits a relationship between students' perceptions of their learning, the enjoyment of the experience and expected future outcomes. The results of our evaluation reveal that a majority of students: ’ enjoyed this way of learning; ’ believed that the exercise assisted their learning of substantive theory, computing applications and the nature of survey data; and ’ felt that what they have learned could be applied elsewhere. We argue that this approach presents the potential to improve the way theory is taught by integrating theory, theory testing and theory development; moving away from teaching theory and analysis in discrete subjects; and, introducing iterative experiences in substantive subjects.
Is Form-Focused Vocabulary Instruction Worthwhile?

Hearing stories can result in considerable incidental vocabulary development, for both first and second language acquisition (e.g. Elley 1992; Robbins and Ehri 1994; Senechal, LeFevre, Hudson and Lawson 1996). It has also been claimed, however, that direct instruction is more effective than incidental vocabulary acquisition and that combining both approaches will be more effective than incidental acquisition alone (Coady 1997). In this study, we compare vocabulary growth in English as a foreign language through hearing a story with a combination of a story and supplementary activities designed to focus students specifically on learning the new words in the story. Subjects were first-year Japanese female students at a junior college in Osaka. One class was the ‘story-only’ group and the other was the ‘story-plus study’ group. The story-only group spent only 15 minutes hearing a story. The story-plus study group spent nearly the entire class period (85 minutes) hearing the story and doing supplementary activities. Calculations of words learned per minute revealed that the story-only group learned words more efficiently. The results suggest that additional focus on form in the form of traditional vocabulary exercises is not as efficient as hearing words in the context of stories.
A fresh look at polymicrobial bloodstream infection in cancer patients

Objectives To assess the current incidence, clinical features, risk factors, aetiology, antimicrobial resistance and outcomes of polymicrobial bloodstream infection (PBSI) in patients with cancer. Methods All prospectively collected episodes of PBSI in hospitalised patients were compared with episodes of monomicrobial bloodstream infection (MBSI) between 2006 and 2015. Results We identified 194 (10.2%) episodes of PBSI and 1702 MBSI (89.8%). The presence of cholangitis, biliary stenting, neutropenia, corticosteroids, neutropenic enterocolitis and other abdominal infections were identified as risk factors for PBSI. Overall, Gram-negative organisms were the most frequent aetiology, but Enterococcus spp. were especially frequent causes of Gram-positive PBSI (30.8%). Multidrug-resistant (MDR) organisms were more commonly found in PBSI than in MBSI (20.6% vs 12.9%; p = 0.003). Compared to patients with MBSI, those with PBSI presented with higher early (15% vs 1.4%; p = 0.04) and overall (32% vs 20.9%; p<0.001) case-fatality rates. Risk factors for overall case-fatality were a high-risk MASCC (Multinational Association of Supportive Care in Cancer) index score, corticosteroid use, persistent bacteraemia and septic shock. Conclusions PBSI is a frequent complication in patients with cancer and is responsible for high mortality rates. Physicians should identify patients at risk for PBSI and provide empiric antibiotic therapy that covers the most frequent pathogens involved in these infections, including MDR strains.
Cascade training and teachers' professional development

In their concern with ‘improved’ curricula and ‘more effective’ teaching-learning methods, education ministries often use the ‘cascade’ model to attempt to effect large-scale change at the classroom level. Experience of cascades in in-service development has tended to show, however, that the cascade is more often reduced to a trickle by the time it reaches the class-room teacher, on whom the success of curricular change depends. This paper examines the experience of a nationwide in-service teacher development project in Sri Lanka which aims to remedy the potential deficiencies of cascade models of teacher development It shows how project training and development strategies which are context sensitive, collaborative, and reflexive seek to involve teachers in managing their own professional growth, while at the same time taking account of frameworks agreed at the national level. In this way a cascade model of training may promote genuine development rather than surface adherence to official mandates.
Acquisition of article semantics by child and adult L2-English learners*

This paper examines article use in the L2-English of adult and child speakers of Russian, an article-less language. In earlier work on articles in adult L2-English, Ionin, Ko and Wexler (2004) proposed that speakers of article-less L1s fluctuate between dividing English articles on the basis of definiteness vs. specificity, as a result of direct access to semantic universals. The present paper examines whether similar fluctuation is present for child L2-English learners. Results of an elicitation study with L1-Russian child and adult learners of English show that both groups of learners exhibit sensitivity to definiteness as well as specificity. At the same time, it is found that the behavior of child L2-learners is more consistent with natural language data than that of adult L2-learners. It is proposed that both children and adults have domain-specific knowledge of semantic universals, but that adults, unlike children, also use explicit strategies. This proposal is considered in light of the literature on explicit vs. implicit knowledge.
Levetiracetam as Adjunctive Antiepileptic Therapy for Patients with Tuberous Sclerosis Complex: A Retrospective Open-Label Trial

Seizures are a common neurologic symptom of tuberous sclerosis complex. The use of levetiracetam as adjunctive antiepileptic therapy was assessed in 20 patients with tuberous sclerosis complex aged 2 to 19 years. In this retrospective evaluation, 40% of patients treated with levetiracetam achieved a seizure reduction of more than 50%. Levetiracetam was generally well tolerated, and adverse events were relatively uncommon in patients who responded to treatment. The most commonly reported adverse events were behavioral problems. Unstable gait, insomnia, poor appetite, and increased seizure frequency were also reported. Based on these results, the use of levetiracetam as adjunctive antiepileptic therapy can reduce seizure frequency in patients with tuberous sclerosis complex. (J Child Neurol 2006;21:53—57).
Isolation and technology: the human disconnect

Management control over production has often meant control over one means of production: people. There is evidence of the use of social isolation to control human behavior throughout recorded history. Traces the development of social isolation through the multiple lenses of management, economics, psychology, sociology, engineering technology, social psychology, and communication science and presents a taxonomy of perspectives for discussion. The taxonomy is further elucidated through the assignment and distribution of 13 organizational factors for both the objective state and subjective feelings of social isolation as linked to advances in telecommuting and other off‐site “open collar” work.
Changes in health indicators related to health promotion and microcredit programs in the Dominican Republic.

OBJECTIVE To assess the impact of health promotion programs and microcredit programs on three communities in the Dominican Republic. One community had only the health promotion program, one community had only the microcredit program, and one community had both a health promotion program and a microcredit program. This pilot project examined the hypothesis that the largest changes in 11 health indicators that were studied would be in the community with both a health promotion program and a microcredit program, that there would be intermediate changes in the community with only a health promotion program, and that the smallest changes would be in the community with only a microcredit program. METHODS The health promotion programs used community volunteers to address two major concerns: (1) the prevalent causes of mortality among children under 5 years of age and (2) women's health (specifically breast and cervical cancer screening). The microcredit program made small loans to individuals to start or expand small businesses. Outcome measures were based on comparisons for 11 health indicators from baseline community surveys (27 households surveyed in each of the three communities, done in December 2000 and January 2001) and from follow-up surveys (also 27 households surveyed in each of the three communities, in June and July 2002, after the health promotion program had been operating for about 13 months). Households were randomly chosen during both the baseline and follow-up surveys, without regard to their involvement in the microcredit or health promotion programs. RESULTS The health indicators improved in all three communities. However, the degree of change was different among the communities (P < 0.001). The community with parallel microcredit and health promotion programs had the largest changes for 10 of the 11 health indicators. CONCLUSIONS Multisector development is known to be important on a macroeconomic scale. The results of this pilot project support the view that multisector development is also important on a microeconomic level, given that the parallel microcredit and health promotion programs resulted in greater change in the measured health indicators than either program alone. As far as we authors know, this is the first published study to quantify changes in health indicators related to parallel health promotion and microcredit programs as compared to control communities with only a health promotion program or a microcredit program.