Miracle-dz/UniFAR-FTUs huggingface dataset:
Oral pyogenic granuloma: Various concepts of etiopathogenesis

Pyogenic granuloma or granuloma pyogenicum is a well-known oral lesion. The name pyogenic granuloma is a misnomer since the condition is not associated with pus and does not represent a granuloma histologically. Pyogenic granuloma of the oral cavity is known to involve the gingiva commonly. Extragingivally, it can occur on the lips, tongue, buccal mucosa, palate, and the like. A history of trauma is common in such sites. The etiology of the lesion is not known, though it was originally believed to be a botryomycotic infection. It is theorized that pyogenic granuloma possibly originates as a response of tissues to minor trauma and/or chronic irritation, thus opening a pathway for invasion of nonspecific microorganisms, although microorganisms are seldom demonstrated within the lesion. Pathogenesis of pyogenic granuloma is still debatable. Medline and PubMed databases were searched under the following key terms: Pathogenesis of oral pyogenic granuloma, pyogenic granuloma, and oral pyogenic granuloma. This search was limited to articles on human/animal studies which were published in English language. After reviewing the searched articles, the relevant articles were selected for the present review. Through this article, we have tried to summarize and present all the concepts of pathogenesis related to this most common and most mysterious oral lesion.
An antigen-independent contact mechanism as an early step in T cell- proliferative responses to dendritic cells

Dendritic cells bearing antigen efficiently aggregate and stimulate antigen-specific T cells. We describe an experimental model in which an initial, apparently antigen-independent binding step is followed by ligation of the TCR. The model is the polyclonal response to mAb to the CD3 portion of the TCR complex. Epidermal and thymic dendritic cells utilize low levels of Fc receptors to present the anti-CD3 mAb and induce mitogenesis. Within 3 h of coculture, most of the dendritic cells have formed clusters with the resting T lymphocytes, and these clusters are the site for subsequent DNA synthesis and cell growth. However, the binding of dendritic cells to T cells proceeds as efficiently in the absence of anti-CD3 as in its presence, and anti-FcR mAb does not block. CD3 and Fc receptors are essential for the subsequent mitogenesis response in dendritic-T cell clusters. Because an exogenous ligand for the TCR does not seem to be required for the extensive polyclonal clustering of resting lymphocytes to dendritic cells, we suggest that an antigen-independent mechanism mediates the initial interaction. This clustering seems essential for T cell growth since we do not detect, in two-chamber experiments, soluble lymphocyte- activating factors that originate from dendritic-T cell aggregates and that activate anti-CD3-coated T cells.
An empirical analysis of gender differences in sports attendance motives

In Australia, male sports attendees outnumber female sports attendees by 25%, yet little research has been conducted into the attendance motives of women. This study undertakes an analysis of 460 respondents using descriptive and multivariate statistics to distinguish the attendance motivations of women and compare them directly to those of male attendees. The findings suggest that female attendance can be influenced through management and promotional strategies.
Le commerce équitable face aux nouveaux défis commerciaux : évolution des dynamiques d'acteurs

Partant du constat d’une extension des marches de produits equitables, cette recherche analyse la recomposition de ce secteur et ses impacts sur les capacites d’action des acteurs du Sud. La recherche a privilegie des cas d’etudes de filieres et produits peu etudies, a savoir le cacao, les filieres d’artisanat et la filiere coton en esperant rendre compte de la diversite du commerce equitable sans pretendre le decrire de maniere exhaustive. A partir d’une approche sociologique, la recherche s’est attachee a : - Analyser la recomposition des marches. Constatant l’allongement des filieres avec l’intervention de nouveaux partenaires commerciaux ; l’emergence de filieres nouvelles, parfois concurrentes des filieres « classiques » des ONG et la complexification des filieres avec des operations de labellisation, de certification appuyees sur un debut de formulation de « normes », la recherche vise a caracteriser les changements lies a l’extension des marches en particulier en terme d’echelle (dimension des marches, des entreprises), de formes contractuelles (exigences nouvelles), et d’organisation des acteurs. - Analyser la reformulation du referentiel. Comme filiere de qualite specifique, le commerce equitable repose sur des definitions conventionnelles qui engagent des valeurs, lesquelles se traduisent dans des normes, des formes d’organisation, voire des croyances que doivent partager (a un certain degre) les acteurs qui participent a ces filieres. En bref les exigences d’equite du commerce equitable forment un socle a la fois normatif et cognitif qui est necessaire au bon fonctionnement de la filiere. Ce socle commun que nous appelons referentiel est-il menace ou mis en question par la recomposition du marche, l’irruption de nouveaux acteurs, la formalisation des relations a travers une labellisation et une certification ? - Evaluer les impacts au Sud. Apres avoir cherche a rendre compte des diversites des logiques et des dynamiques en œuvre au Sud, il s’agissait d’evaluer les consequences sur ces dynamiques des transformations observees au Nord. Une attention particuliere etait portee a l’empowerment des femmes.
Clinical and Sociocultural Factors Associated With Failure to Escalate Care of Deteriorating Patients

In-hospital medical emergencies occur frequently. Understanding how clinicians respond to deteriorating patients outside the intensive care unit (ICU) could improve “rescue” interventions and rapid response programs. This was a qualitative study with interviews with 40 clinicians caring for patients who had a “Code Blue” activation or an unplanned ICU admission at teaching hospitals over 7 months. Four study physicians independently analyzed interview transcripts; refined themes were linked to the transcript using text analysis software. Nine themes were found to be associated with clinicians’ management of deteriorating patients. Multiple human biases influence daily care for deteriorating hospitalized patients. A novel finding is that “moral distress” affects escalation behavior for patients with poor prognosis. Most themes indicate that ward culture influences clinicians to wait until the last minute to escalate care despite being worried about the patients’ condition.
Evaluation of the Immunoglobulin G Avidity Test for Diagnosis of Toxoplasmic Lymphadenopathy

ABSTRACT Toxoplasmic lymphadenopathy (TL) is the most common clinical manifestation of acute acquired toxoplasma infection in normal individuals. The diagnosis is established by serologic methods and lymph node biopsy. Recently, tests for avidity of toxoplasma immunoglobulin G (IgG) antibodies have been introduced to help discriminate between recently acquired and distant infection with the parasite. We studied an avidity test to define the usefulness of this method and to determine the evolution of the IgG avidity in TL. Seventy-three consecutive patients diagnosed as having TL were studied. IgG avidity test titers were noted to be time dependent from the clinical onset of lymphadenopathy. Low IgG avidity test results were observed in patients who had developed lymphadenopathy from <1 month to 17 months prior to the sampling of sera, emphasizing that low IgG avidity test results are not reliable for diagnosis of recently acquired infection. In contrast, high IgG avidity test results were observed only in patients who had developed lymphadenopathy at least 4 months earlier. Thus, a high IgG avidity test result in an individual who has recent onset of lymphadenopathy (e.g., within 2 to 3 months of sera sampling) suggests a cause other than toxoplasmosis. In such cases, further workup is warranted in order to determine the cause of the lymphadenopathy.
Link Inference in Dynamic Heterogeneous Information Network: A Knapsack-Based Approach

Link inference, i.e., inferring links between vertices in a heterogeneous information network with heterogeneous vertices and edges, has been extensively studied in recent years. So far, many machine learning-based methods have been proposed for link inference, which can be classified into two categories, namely, supervised and unsupervised. Supervised methods perform well but highly rely on feature selection and training data. Although unsupervised methods are inferior to supervised ones, they work in a relatively simple way without considering the class distribution of the training data. In this paper, we investigate the link inference problem in heterogeneous information networks by proposing a knapsack-constrained inference method. Specifically, we integrate dynamic information into the heterogeneous information network and further formalize the link inference problem as a knapsack-like problem. We then solve it by the virtue of a 0–1 knapsack analogous optimization approach and investigate the time complexity of the proposed approach. Finally, experimental results show that the proposed unsupervised method can obtain high performance comparable to supervised method for some cases.
Cross‐cultural differences in conflict management: An inductive study of Chinese and American managers

Purpose – The purpose of this paper is to compare conflict management behaviors of American and Chinese managers. Its main aim is to uncover cultural differences in the way Chinese and American managers approach conflict – thereby developing a more thorough understanding of conflict management across cultures.Design/methodology/approach – Inductive analysis is used to uncover conflict management constructs that are unique to each culture. Structured interviews and multidimensional scaling techniques are used.Findings – Results show that the conflict management behaviors suggested by American and Chinese managers are different. For Chinese managers alone, embarrassing the colleague and teaching a moral lesson is an important element. For American managers alone, hostility and vengefulness are important elements. Results suggest that both cultures acknowledge avoidant approaches, but the underlying intentions for Americans alone are associated with a lack of confidence.Research limitations/implications – Re.
Quantification of soil erosion rates related to ancient Maya deforestation

We used seismic and sediment core data to quantify soil erosion rates for the past ~6000 yr in the closed catchment of Lake Salpeten, in the tropical lowlands of northern Guatemala. The region was affected by ancient Maya land use from before ca. 1000 B.C. to A.D. 900. This period of human impact coincided with deposition in the lake of a detrital unit (Maya Clay) as much as 7 m thick that contrasts sharply with the relatively organic-rich gyttja deposited both before and after Maya occupation of the watershed. The greatest soil loss, with mean sustained values of ~1000 t/km2yr–1, occurred in the Middle and Late Preclassic Periods (700 B.C. to A.D. 250), associated with relatively low Maya population densities. Soil erosion slowed during the period of maximum population density in the Late Classic Period (A.D. 550–830), indicating a decoupling between human population density and soil erosion rate. The most rapid soil loss occurred early during initial land clearance, suggesting that even low numbers of people can have profound impacts on lowland tropical karst landscapes.
Girls Talk: Authorship and Authenticity in the Reception of Lena Dunham's Girls

By examining the discourse around Lena Dunham's HBO comedy Girls (2012–present), this article argues that the programme served as a space to think through female authorship, televisual representations and cultural tensions surrounding young womanhood. Central to this discourse was the narrative asserting Girls' and Dunham's ‘authenticity’, originality and universality, which sought to legitimate her gendered authorship and interest in the comedy of female intimacy within HBO's masculine prestige channel identity. Charting three cycles of discourse surrounding the programme's debut, this article explores the paratextual framing by promotional concerns, television critics and women's websites. It highlights how journalists and critics furthered HBO's paratextual framing of Dunham, which was later countered by the networked spaces of niche online media, which used the programme as a space to productively work through industrial and cultural tensions; particularly those surrounding female comic authorship, autobiography and intersectionality.
BEBERAPA FAKTOR YANG MEMPENGARUHI SISA HASIL USAHA (SHU) KPRI BINA RAHARJA CERME-GRESIK

Koperasi bertujuan mensejahterakan anggota khususnya dan masyarakat pada umumnya. Untuk mencapai hal tersebut koperasi harus melakukan perluasan investasi demi memperoleh keuntungan atau laba, dalam perkoperasian disebut sebagai sisa hasil usaha. Atas dasar pemikiran tersebut penelitian ini bertujuan untuk mengetahui dan menguji secara empiris dan membuktikan adanya pengaruh hubungan antara jumlah anggota, jumlah simpanan, jumlah pinjaman dan modal kerja terhadap perolehan sisa hasil usaha (SHU) KPRI Bina Raharja. Penelitian ini menggunakan data sekunder yaitu data time series pada tahun 2003-2012. Analisis yang digunakan dalam penelitian ini adalah regresi linear berganda dan variabel yang digunakan adalah Jumlah Anggota (X), Jumlah Simpanan (X2), Jumlah Pinjaman (X3), Modal Kerja (X4) dan Sisa Hasil Usaha (Y) sebagai variabel terikatnya. Hasil dari penelitian ini menunjukkan bahwa Jumlah Anggota (X),Jumlah Simpanan (X2), Jumlah Pinjaman (X3), Modal Kerja (X) mempunyai pengaruh terhadap Sisa Hasil Usaha (Y) di KPRI Bina Raharja dapat terbukti kebenarannya. Dan variabel Jumlah Simpanan (X) merupakan variabel yang mempunyai pengaruh paling dominan terhadap perolehan sisa hasil usaha di KPRI Bina Raharja dengan nilai R22 sebesar 98 % dan sisanya 2% dijelaskan oleh variabel lain yang tidak dibahas dalam masalah penelitian ini. Kata kunci : Sisa Hasil Usaha, Jumlah Anggota, Jumlah Simpanan, Jumlah Pinjaman, Modal Kerja
Towards an enumerative geometry of the moduli space of twisted curves and rth roots

Abstract The enumerative geometry of rth roots of line bundles is crucial in the theory of r-spin curves and occurs in the calculation of Gromov–Witten invariants of orbifolds. It requires the definition of the suitable compact moduli stack and the generalization of the standard techniques from the theory of moduli of stable curves. In a previous paper, we constructed a compact moduli stack by describing the notion of stability in the context of twisted curves. In this paper, by working with stable twisted curves, we extend Mumford’s formula for the Chern character of the Hodge bundle to the direct image of the universal rth root in K-theory.
Factorization for Hardy spaces and characterization for BMO spaces via commutators in the Bessel setting

Fix $\lambda>0$. Consider the Hardy space $H^1(\mathbb{R}_+,dm_\lambda)$ in the sense of Coifman and Weiss, where $\mathbb{R_+}:=(0,\infty)$ and $dm_\lambda:=x^{2\lambda}dx$ with $dx$ the Lebesgue measure. Also consider the Bessel operators $\Delta_\lambda:=-\frac{d^2}{dx^2}-\frac{2\lambda}{x} \frac d{dx}$, and $S_\lambda:=-\frac{d^2}{dx^2}+\frac{\lambda^2-\lambda}{x^2}$ on $\mathbb{R_+}$. The Hardy spaces $H^1_{\Delta_\lambda}$ and $H^1_{S_\lambda}$ associated with $\Delta_\lambda$ and $S_\lambda$ are defined via the Riesz transforms $R_{\Delta_\lambda}:=\partial_x (\Delta_\lambda)^{-1/2}$ and $R_{S_\lambda}:= x^\lambda\partial_x x^{-\lambda} (S_\lambda)^{-1/2}$, respectively. It is known that $H^1_{\Delta_\lambda}$ and $H^1(\mathbb{R}_+,dm_\lambda)$ coincide but they are different from $H^1_{S_\lambda}$. In this article, we prove the following: (a) a weak factorization of $H^1(\mathbb{R}_+,dm_\lambda)$ by using a bilinear form of the Riesz transform $R_{\Delta_\lambda}$, which implies the characterization of the BMO space associated to $\Delta_\lambda$ via the commutators related to $R_{\Delta_\lambda}$; (b) the BMO space associated to $S_\lambda$ can not be characterized by commutators related to $R_{S_\lambda}$, which implies that $H^1_{S_\lambda}$ does not have a weak factorization via a bilinear form of the Riesz transform $R_{S_\lambda}$.
Impact of reserve market integration on the value of the North Sea offshore grid alternatives

Expected large scale integration of offshore wind power in the North Sea in future scenarios, 2020-2030, contribute to challenges on transmission planning and system operation in the Northern European electricity network. Moreover, the intermittency of the renewable resources makes the operational planning, forecasting, balancing, and control of the system more challenging. In this paper, a comparison is carried out between two reserve procurement market models. This is done by simulating non- and fully-integrated Northern European market using a 2030 scenario in combination with the effect of two different strategies for the development of the North Sea offshore grid: Radial grid and Meshed grid. The day-ahead market is modeled as a common market on an aggregate level for the whole European continent. Reserve procurement is done simultaneously with the clearing of the day-ahead market. For the analysis of day-ahead dispatch, a DC optimal power flow is used. The results show that about EUR 262 million and EUR 326 million per year could be saved as a result of the integration of the Northern European reserve market for the meshed and radial offshore grid topologies respectively.
Autophagic dysfunction in mucolipidosis type IV patients

Mutations in Mucolipin 1 (MCOLN1) have been linked to mucolipidosis type IV (MLIV), a lysosomal storage disease characterized by several neurological and ophthalmological abnormalities. It has been proposed that MCOLN1 might regulate transport of membrane components in the late endosomal–lysosomal pathway; however, the mechanisms by which defects of MCOLN1 function result in mental and psychomotor retardation remain largely unknown. In this study, we show constitutive activation of autophagy in fibroblasts obtained from MLIV patients. Accumulation of autophagosomes in MLIV cells was due to the increased de novo autophagosome formation and to delayed fusion of autophagosomes with late endosomes/lysosomes. Impairment of the autophagic pathway led to increased levels and aggregation of p62, suggesting that abnormal accumulation of ubiquitin proteins may contribute to the neurodegeneration observed in MLIV patients. In addition, we found that delivery of platelet-derived growth factor receptor to lysosomes is delayed in MCOLN1-deficient cells, suggesting that MCOLN1 is necessary for efficient fusion of both autophagosomes and late endosomes with lysosomes. Our data are in agreement with recent evidence showing that autophagic defects may be a common characteristic of many neurodegenerative disorders.
Gender issues in French geography

In recent years French geographers have undertaken research that either includes gender issues or focuses on questions of the geography of women. This is attested to by the publication of monographic issues of some journals as well as a colloquium held in 2004. The interest in gender and /or women is not new, but for a long time it remained barely visible and did not generate discussion within the discipline. This situation calls for an inquiry into the increased visibility of current research. How have developments been influenced by factors such as scientific, sociological, national and international contexts, and by the changing demographic make up of French geographers (by sex, generation, and status) ? The paper notes that attention to gender studies in French geography has largely been evident in relation to development, urban studies, migration and mobility, though gender geographers can also make important contributions to current debates on public policies, time geography, the impact of globalisation and urban violence.
Privacy and Behavioral Advertising: Towards Meeting Users' Preferences

Online advertisers track Internet users’ activities to deliver targeted ads. To study how dierent factors aect users’ attitudes towards this practice, we conducted a betweensubjects online study (n=1,882). We elicited participants’ comfort with sharing commonly collected types of information in scenarios with varying online advertisers’ data practices. Quantitative analysis showed that participants’ willingness to share information with online advertisers is not only based on the sensitivity of the information, but also on the scope of collection and use, relevance for advertising, and perceived benets of disclosing specic data types. Qualitative analysis showed nuanced and individualized preferences, which suggest that personalized privacy agents have the potential to better assist users to control how advertising networks collect and use their information.
Intranasal Antifungal Therapy in Patients with Chronic Illness Associated with Mold and Mycotoxins: An Observational Analysis

Exposure to mycotoxin producing mold and mycotoxins can be associated with numerous adverse health consequences. We previously reported that patients with chronic illness frequently had a history of prior exposure to water damaged buildings (WDB) and mold. Additionally, the vast majority of these patients had mycotoxins present in the urine. We have postulated that the mycotoxin producing molds were likely harbored internally in the sinuses of these patients. In the present analysis, patients with chronic illness and a positive urine mycotoxin assay were treated with intranasal antifungal therapy, either amphotericin B (AMB) or itraconazole (ITR). AMB was associated with local (nasal) irritation adverse effects (AE) in 34% of the cases, which resulted in discontinuation. In patients that remained on therapy without AE, we found that 94% improved clinically. Additionally, we found that the urine mycotoxin levels decreased substantially in patients that improved on therapy. Similar findings were seen with ITR, however the number of patients treated was much smaller.
The interactive parameters estimation of multiple space robot manipulators

During the operation process of multiple space robot manipulators, the estimation problem of manipulators inherent parameters and target inertial parameters should be solved first. In this paper, we propose an interactive identification algorithm for this problem. This method considers convergence and consensus of estimated results in the meantime. A further application of this method in structure shock model parameters of flexible link manipulators and inertial parameters of the object grasping by multiple robots is presented. In addition, we make a further discussion and analysis about the convergence of this method in the situation of dropping back and containing invalid data. The simulation results show t hat compared with respective estimated results, the estimated results converge faster with smaller errors, which is effective to avoid the influence of non-white noise and discontinuous invalid measured data. We conclude this paper in the end.