Miracle-dz/UniFAR-FTUs huggingface dataset:
An examination of the transition from primary to secondary school for children with an autistic spectrum disorder (ASD) in one local authority

Many children can find it difficult to adjust to the social and curriculum differences they encounter when they begin secondary school. For some children — particularly children with a special educational need (SEN) — a difficult transition from primary to secondary school undermines educational, social and emotional outcomes. Children diagnosed with an autism spectrum disorder (ASD) are known to be especially vulnerable at the time of secondary transition. It is well recognised amongst practitioners that these children have a profile of needs, including difficulties in social communication, problems coping with the sensory environment, and anxiety difficulties, which can potentially make changing schools particularly difficult. Despite this knowledge, there is a paucity of academic research that has focused specifically on this group of children at the time of secondary transition. This study aimed, for the first time, to examine the factors that both support and hinder a successful transition from primary to secondary school for children with an ASD in one local authority. Adopting an eco-systemic perspective and utilising a mixed methodology, this study investigated which potential intrinsic characteristics of the child and wider systemic factors influenced the secondary transition process for 15 children with an ASD. Children were seen twice in the space of 3 months — once before the process of changing school and once the move to secondary school was made. This longitudinal design enabled the examination of any possible changes in the views and perspectives of children, parents, and teachers during the transition process, in addition to the impact of systemic factors on the process. It also allowed for investigation of the possible pre-transition predictors — the intrinsic needs of the child with ASD — of a successful transition. Specifically, it was expected that children with better verbal ability, fewer autistic symptoms, fewer sensory issues, and reduced anxiety levels would experience a smoother transition. Unexpectedly, this study found no significant associations between pre-transition intrinsic ASD child characteristics and overall transition success. Nevertheless, it identified several systemic factors, including the child's identity, tensions over school choice, delay in placement decisions, lack of primary preparation and in-reach, which were found to have a strong influence on the process of secondary transition for the children and their families. Intriguingly, the children who transitioned from mainstream to specialist provisions were identified as experiencing particular difficulties coping with their new secondary school. These findings have important implications for the role of educational psychologists in the transition process.
Antimalarial Evaluation of the Chemical Constituents of Hairy Root Culture of Bixa orellana L.

Over 216 million malaria cases are reported annually worldwide and about a third of these cases, primarily children under the age of five years old, will not survive the infection. Despite this significant world health impact, only a limited number of therapeutic agents are currently available. The lack of scaffold diversity poses a threat in the event that multi-drug–resistant strains emerge. Terrestrial natural products have provided a major source of chemical diversity for starting materials in many FDA approved drugs over the past century. Bixa orellana L. is a popular plant used in South America for the treatment of malaria. In search of new potential therapeutic agents, the chemical constituents of a selected hairy root culture line of Bixa orellana L. were characterized utilizing NMR and mass spectrometry methods, followed by its biological evaluation against malaria strains 3D7 and K1. The crude extract and its isolated compounds demonstrated EC50 values in the micromolar range. Herein, we report our findings on the chemical constituents of Bixa orellana L. from hairy roots responsible for the observed antimalarial activity.
Eccentric Loading versus Eccentric Loading plus Shock-Wave Treatment for Midportion Achilles Tendinopathy

Background Results of a previous randomized controlled trial have shown comparable effectiveness of a standardized eccentric loading training and of repetitive low-energy shock-wave treatment (SWT) in patients suffering from chronic midportion Achilles tendinopathy. No randomized controlled trials have tested whether a combined approach might lead to even better results. Purpose To compare the effectiveness of 2 management strategies—group 1: eccentric loading and group 2: eccentric loading plus repetitive low-energy shock-wave therapy. Study Design Randomized controlled trial; Level of evidence, 1. Methods Sixty-eight patients with a chronic recalcitrant (>6 months) noninsertional Achilles tendinopathy were enrolled in a randomized controlled study. All patients had received unsuccessful management for >3 months, including at least (1) peritendinous local injections, (2) nonsteroidal anti-inflammatory drugs, and (3) physiotherapy. A computerized random-number generator was used to draw up an allocation schedule. Analysis was on an intention-to-treat basis. Results At 4 months from baseline, the VISA-A score increased in both groups, from 50 to 73 points in group 1 (eccentric loading) and from 51 to 87 points in group 2 (eccentric loading plus shock-wave treatment). Pain rating decreased in both groups, from 7 to 4 points in group 1 and from 7 to 2 points in group 2. Nineteen of 34 patients in group 1 (56%) and 28 of 34 patients in group 2 (82%) reported a Likert scale of 1 or 2 points (“completely recovered” or “much improved”). For all outcome measures, groups 1 and 2 differed significantly in favor of the combined approach at the 4-month follow-up. At 1 year from baseline, there was no difference any longer, with 15 failed patients of group 1 opting for having the combined therapy as cross-over and with 6 failed patients of group 2 having undergone surgery. Conclusion At 4-month follow-up, eccentric loading alone was less effective when compared with a combination of eccentric loading and repetitive low-energy shock-wave treatment.
Desenho universal e avaliação psicológica na perspectiva dos direitos humanos

Universal design and psychological assessment in a human rights perspective Universal design involves the process of designing materials, tools, objects, buildings and environments in a way that are accessible to most people, independent of being disabled or not. We understand that the use of the concepts of universal design in the development and adaptation of methods for psychological assessment can represent the search for human rights, since it allows both the use of these techniques for psychologists with disabilities and the psychological assessment of people with disabilities. Legal and technical documents related to the development and adaptation of psychological tests and Universal Design were reviewed. This paper proposes some ways of using Universal Design concepts in the research and professional use of psychological assessment. The use of Universal Design concepts in the field of psychological assessment is aligned with the historic commitment of Psychology with democratic principles and the search for social inclusion of people with disabilities.
Identifying biomarkers as diagnostic tools in kidney transplantation

There is a critical need for biomarkers for early diagnosis, treatment response, and surrogate end point and outcome prediction in organ transplantation, leading to a tailored and individualized treatment. Genomic and proteomic platforms have provided multiple promising new biomarkers during the last few years. However, there is still no routine application of any of these markers in clinical transplantation. This article will discuss the existing gap between biomarker discovery and clinical application in the kidney transplant setting. Approaches to implementing biomarker monitoring into clinical practice will also be discussed.
Brentuximab vedotin in patients with Hodgkin lymphoma and a failed allogeneic stem cell transplantation: results from a named patient program at four Italian centers.

BACKGROUND Brentuximab vedotin (BV) has demonstrated an extraordinary efficacy in heavily pretreated classical Hodgkin lymphoma (cHL) patients, targeting CD30-positive cells; however, limited data have been reported on the efficacy of BV in cHL patients failing allogeneic stem cell transplantation (allo-SCT). The aim of this study was to retrospectively evaluate the efficacy and safety of BV in a multicenter setting of cHL relapsing or progressing after allo-SCT. METHODS Sixteen BV-naïve patients with recurrent cHL after allo-SCT were included in a compassionate use program and treated with intravenous BV at the dose of 1.8 mg/kg of body weight every 3 weeks for a maximum of 16 cycles. RESULTS The objective response rate was 69%. Five patients (31%) had complete remission, and 6 (37%) had partial remission. Stable disease was observed in 4 patients (25%), and progressive disease was observed in 1 (6%). After median follow-up of 26 months (range: 5-30 months), median progression-free survival (PFS), overall survival (OS), and duration of response were 7, 25, and 5 months, respectively. The 2-year PFS and OS were 20% and 61%, respectively. Grade 3-4 hematological adverse events included anemia (15%), thrombocytopenia (12%), and neutropenia (18%). Grade 3 peripheral sensory neuropathy occurred in 2 patients (12%). CONCLUSION BV therapy is an effective and safe approach for achieving transient disease control in cHL patients with failed allo-SCT. To improve disease control, future studies should explore the combination of BV with targeted agents.
Comparing Images Using the Hausdorff Distance

The Hausdorff distance measures the extent to which each point of a model set lies near some point of an image set and vice versa. Thus, this distance can be used to determine the degree of resemblance between two objects that are superimposed on one another. Efficient algorithms for computing the Hausdorff distance between all possible relative positions of a binary image and a model are presented. The focus is primarily on the case in which the model is only allowed to translate with respect to the image. The techniques are extended to rigid motion. The Hausdorff distance computation differs from many other shape comparison methods in that no correspondence between the model and the image is derived. The method is quite tolerant of small position errors such as those that occur with edge detectors and other feature extraction methods. It is shown that the method extends naturally to the problem of comparing a portion of a model against an image. >
Possibilistic Temporal Reasoning based on Fuzzy Temporal Constraints

In this paper we propose a propositional temporal language based on fuzzy temporal constraints which turns out to be expressive enough for domains -like many coming from medicine- where knowledge is of propositional nature and an explicit handling of time, imprecision and uncertainty are required. The language is provided with a natural possibilistic semantics to account for the uncertainty issued by the fuzziness of temporal constraints. We also present an inference system based on specific rules dealing with the temporal constraints and a general fuzzy modus ponens rule whereby behaviour is shown to be sound. The analysis of the different choices as fuzzy operators leads us to identify the well-known Lukasiewicz implication as very appropriate to define the notion of possibilistic entailment, an essential element of our inference system.
A new approach based on "soft statistics" to the nonlinear blind-deconvolution of unknown data channels

In this paper, we present a new nonlinear receiver for the blind deconvolution of intersymbol interference (ISI) impaired data. The proposed receiver achieves fast identification of an unknown transmission channel using only one channel estimator and requiring the computation of only the second-order conditional statistics of the baud-rate sampled received signal and the knowledge of the transmitted constellation. The main novelty of the proposed approach is that the receiver accomplishes fast channel-identification by using soft-statistics. In particular, the receiver consists of a symbol-by-symbol maximum a posteriori (SbS-MAP) detector that feeds a nonlinear Kalman-like channel estimator with the soft statistics constituted by the a posteriori probabilities (APPs) of the state sequence of the ISI channel. Several numerical results confirm that the proposed blind detector achieves the identification of nonminimum phase channels with deep spectral notches within 300 symbols, even at low signal-to-noise ratios (SNRs). Furthermore, an attractive feature of the proposed blind channel estimator is that it directly estimates the discrete-time impulse response of the unknown channel so that, in principle, any equalization technique for known channels may be performed after channel identification has been achieved.
Non-Heterosexist Organizational Climate and Affirmative Counselor Behaviors: Validation of Instruments.

PUB DATE 2003-08-00 NOTE 24p. ; Paper presented at the Annual Conference of the American Psychological Association (111th, Toronto, ON, Canada, August 7-10, 2003). PUB TYPE Information Analyses (070) Reports Research (143) Speeches/Meeting Papers (150) EDRS PRICE EDRS Price MF01/PC01 Plus Postage. DESCRIPTORS Client Characteristics (Human Services); *Counselor Attitudes; *Counselor Characteristics; *Counselor Client Relationship; *Homophobia; Homosexuality; Lesbianism; *Psychometrics; Test Reliability; Test Validity
OBSERVATIONS OF THE ACTIVE GALACTIC NUCLEUS IN THE SOMBRERO GALAXY ( NGC 4594 )

We present Spitzer 3.6–160 m images, Spitzer mid-infrared spectra, and JCMT SCUBA 850 m images of the Sombrero Galaxy (NGC 4594), an Sa galaxy with a 10 M low-luminosity active galactic nucleus (AGN). The brightest infrared sources in the galaxy are the nucleus and the dust ring. The spectral energy distribution of the AGN demonstrates that, while the environment around the AGN is a prominent source of mid-infrared emission, it is a relatively weak source of far-infrared emission, as had been inferred for AGNs in previous research. The weak nuclear 160 m emission and the negligible polycyclic aromatic hydrocarbon emission from the nucleus also implies that the nucleus is a site of onlyweak star formation activity and the nucleus contains relatively little cool interstellar gas needed to fuel such activity. We propose that this galaxy may be representative of a subset of low-ionization nuclear emission region galaxies that are in a quiescent AGNphase because of the lack of gas needed to fuel circumnuclear star formation and Seyfert-like AGN activity. Surprisingly, the AGN is the predominant source of 850 m emission. We examine the possible emission mechanisms that could give rise to the 850 m emission and find that neither thermal dust emission, CO line emission, bremsstrahlung emission, nor the synchrotron emission observed at radio wavelengths can adequately explain the measured 850 m flux density by themselves. The remaining possibilities for the source of the 850 m emission include a combination of known emission mechanisms, synchrotron emission that is self-absorbed at wavelengths longer than 850 m, or unidentified spectral lines in the 850 m band. Subject headings: galaxies: active — galaxies: individual (NGC 4594) — galaxies: ISM — galaxies: nuclei — infrared: galaxies Online material: color figures
Geographic aspects of tie strength and value of information in social networking

Relations between the dimension of social tie strength and the dimension of value of communicated information have been investigated in the past by researchers such as Mark Granovetter. Also the connection between spatial distance and the existence of ties in social networks with small world characteristics has been discussed by Liben-Nowell and others. In this contribution we aim at investigating the relation between the dimensions spatial distance and non-binary, continuous value of information. Furthermore, we discuss the connection between non-binary, continuous measures for value of information and the dimension of non-binary social, continuous measures of tie strength. We also especially investigate the interrelation between all three dimensions in Social Networking and especially the research question of whether a spatial dependency of the inverse relation between social tie strength and value of information exists which may be named 'Geo-Granovetter effect'. As a basis for our empirical investigations we used a large Twitter dataset, because this Social Medium allows us to simultaneously access spatial, social and informational dimensions of interaction and thus to simultaneously model these three dimensions for Social Networking. We found that the social tie strength decreases as expected with increasing spatial distance among participants in our data-set. We also observed that in general the information value decreases when the tie strength increases and that the value of information is independent from the distance. According to our findings, Social Media such as Twitter don't exhibit a Geo-Granovetter effect.
Formation of Neoproterozoic metamorphic core complexes during oblique convergence ( Eastern Desert , Egypt )

Abst rac t -Ma jo r portions of the Pan-African Orogen in the Eastern Desert of Egypt were formed by island-arc accretion in the Neoproterozoic. These areas are characterized by their lack of major crustal thickening. Metamorphic core complexes occur parallel to the strike of the Eastern Desert Orogen. These domes exhibit polyphase metamorphism and deformation in contrast to the structurally overlying nappes which include ophiolitic mdlanges and island-arc volcanic rocks. These nappes show northwest directed, orogen-parallel thrusting in the internal parts and west to southwest directed imbrication in the external parts of the orogen. Structures related to exhumation of the metamorphic core complexes partition into different displacement paths localized within a crustal-scale wrench corridor of the Najd fault system. Northwest trending orogen-parallel, sinistral strike-slip faults define the western and eastern margins of the domes. North and south dipping low-angle normal faults developed along the northern and southern margins of the domes and form extensional bridges between them. 4°Ar/SSAr ages obtained from syntectonic muscovites within the shear zones gave Neoproterozoic ages of 595. 9_+0.5 and 588. 2_+0.3 Ma. The synchronous activity of strike-slip and normal faults suggests a regional east-west shortening which was accomodated by deep-level basal decollement beneath the metamorphic core complexes and a coeval northwest-southeast, orogen-paral lel extension. This extension was accompanied by intramontane molasse sedimentation and emplacement of calc-alkaline plutons. Since the rapid exhumation of gneisses in the core complexes cannot be explained by thickening of the crust, the authors favour a model which calls for enhanced heat f low along the Najd fault system which would have enabled the formation of syn-extensional plutonism and triggered the exhumation of the metamorphic core complexes. Lateral buoyancy forces were concentrated within the Najd wrench corridor and enabled orogen-parallel extension. Copyright © 1997 Elsevier Science Ltd. All rights reserved
Modes of Interorganizational Imitation: The Effects of Outcome Salience and Uncertainty

We thank Jim Baron, Alison Davis-Blake, Werner DeBondt, Mike Hannan, Matthew Kraatz, Dan Levinthal, Craig Olson, Jeff Pfeffer, Thekla Rura, Andreas Schwab, Sidney Winter, and seminar participants at the Wharton School, Carnegie Mellon, and Stanford University for helpful comments on earlier drafts of this paper. Drawing on neoinstitutional and learning theories, we distinguish three distinct modes of selective interorganizational imitation: frequency imitation (copying very common practices), trait imitation (copying practices of other organizations with certain features), and outcome imitation (imitation based on a practice's apparent impact on others). We investigate whether these imitation modes occur independently and are affected by outcome salience and contextual uncertainty in the context of an important decision: which investment banker to use as adviser on an acquisition. Results of testing hypotheses on 539 acquisitions that occurred in 1988-1993 show that all three imitation modes occur independently, but only highly salient outcomes sustain outcome imitation. Uncertainty enhances frequency imitation, but only some trait and outcome imitation. The results highlight the possible joint operation of social and technical indicators in imitation, illuminate factors that moderatewvicarious learning processes, and show asymmetries between learning from success and failure. '
Antibiotic resistance and plasmid profiling of Vibrio parahaemolyticus isolated from cockles in Padang, Indonesia

Vibrio parahaemolyticus is one of the most widely recognized pathogenic Vibrio species due to numerous outbreaks and its’ wide occurrence in marine environment. In this study, 32 isolates of V.parahaemolyticus isolated from cockles were tested for sensitivity to 16 antibiotics and the presence of plasmids. All the isolates were multi-resistance, defined as resistant to atleast three different antibiotics with multiple antibiotic resistance indexes ranging from 0.31 to 0.69, indicating the isolates originate from high risk sources of contamination where antibiotics are often used. In the plasmid profiling test, only 15 isolates(47%) harbored plasmid DNA, which ranged in size from 2.7 to 56.2 kb, separating the isolates into 14 plasmid profiles. Hence, food contaminated with antibiotic resistant V. parahaemolyticus could be a major threat to public health due to the distinct possibility that they can be a significant reservoir of genes encoding antibiotic resistance determinants that can be transferred intra or interspecies. As in many developing countries, raw food hygiene and antimicrobial resistance epidemiology is still in the infancy stage in the locality of the study and thus our data provide a current baseline profile of antimicrobial resistance and plasmid of V. parahaemolyticus from cockles in Padang, Indonesia.
An adaptive iterative learning control algorithm with experiments on an industrial robot

An adaptive iterative learning control (ILC) algorithm based on an estimation procedure using a Kalman filter and an optimization of a quadratic criterion is presented. It is shown that by taking the measurement disturbance into consideration the resulting ILC filters become iteration-varying. Results from experiments on an industrial robot show that the algorithm is successful also in an application.