Miracle-dz/UniFAR-FTUs huggingface dataset:
Preoperative factors related to the ambulatory status at 1 year after total knee arthroplasty

Abstract Purpose: The purpose of this study is to investigate whether preoperative factors can predict the ambulatory status at 1 year after primary total knee arthroplasty (TKA). Methods: The subjects were 115 patients who had undergone TKA. Isometric lower limb muscle strength was measured and the Timed Up and Go (TUG) test and the 2011 knee society scoring were conducted preoperatively. Then, the patients were divided into two groups after surgery: a cane-assisted walking group (n = 42) and independent walking group (n = 73). Unpaired t-test, chi-square test, Mann–Whitney U-test, logistic regression analysis and the receiver-operating characteristic curve analysis were used in this study. Results: A multiple logistic regression analysis selected age, TUG test and functional activities as significant variables estimating the use of a cane after surgery. Receiver-operating characteristic curve analyses revealed that the cut-off score for TUG test was 10.8 s (sensitivity = 69%, specificity = 67%, area under curve = 0.81) and the cut-off score for functional activities was 39 points (sensitivity = 83%, specificity = 63%, area under curve = 0.83) in predicting the ambulatory status. Conclusions: Preoperative TUG test with a cut-off score of 10.8 s and functional activities with a cut-off score of 39 points are reliable assessment tools for predicting the use of walking aid following TKA. Implications for Rehabilitation An accurate prediction of the ambulatory status after total knee arthroplasty can aid patients in understanding their own goals of the activities of daily living. Preoperative timed up and go test of <10.8 s and a preoperative functional activities functional activities score in the 2011 knee society scoring >39 points are useful for predicting the ambulatory status after total knee arthroplasty.
Communication contention in task scheduling

Task scheduling is an essential aspect of parallel programming. Most heuristics for this NP-hard problem are based on a simple system model that assumes fully connected processors and concurrent interprocessor communication. Hence, contention for communication resources is not considered in task scheduling, yet it has a strong influence on the execution time of a parallel program. This paper investigates the incorporation of contention awareness into task scheduling. A new system model for task scheduling is proposed, allowing us to capture both end-point and network contention. To achieve this, the communication network is reflected by a topology graph for the representation of arbitrary static and dynamic networks. The contention awareness is accomplished by scheduling the communications, represented by the edges in the task graph, onto the links of the topology graph. Edge scheduling is theoretically analyzed, including aspects like heterogeneity, routing, and causality. The proposed contention-aware scheduling preserves the theoretical basis of task scheduling. It is shown how classic list scheduling is easily extended to this more accurate system model. Experimental results show the significantly improved accuracy and efficiency of the produced schedules.
The effect of exercise on the central‐chemoreceptor threshold in man.

1. The threshold of the central chemoreceptors was determined under resting and three exercise conditions in four volunteers. 2. The method used was the hyperoxic, Read rebreathing technique with prior hyperventilation. Plots of resting ventilation vs. carbon dioxide consisted of two straight‐line segments of different slopes above and below a breakpoint which was taken as the central‐chemoreceptor threshold at rest. 3. The threshold during exercise was determined from plots of exercise ventilation vs. carbon dioxide in a similar way, but the points for these plots were obtained in a different manner. They were obtained from a number of separate rebreathing experiments, so as to avoid the divergence between mouth and central‐chemoreceptor carbon dioxide levels during rebreathing in exercise. 4. Exercise was started abruptly during rebreathing experiments similar to those at rest, at a particular level of carbon dioxide, and exercise ventilation was measured at the third breath. Each rebreathing experiment therefore provides one point for the exercise ventilation vs. carbon dioxide plot. 5. The results showed that the central‐chemoreceptor threshold during exercise was not different from the resting threshold, and that the initial, fast component of exercise ventilation was independent of the chemical drive to breathe.
Effect of latanoprost on outflow facility in the mouse.

PURPOSE To assess the early effect of latanoprost on outflow facility and aqueous humor dynamics in the mouse. METHODS Aqueous humor dynamics in NIH Swiss White mice were assessed with an injection and aspiration system, using fine glass microneedles. A single 200-ng (4 microL) dose of latanoprost was applied to one eye 2 hours before measurement. The fellow eye served as a control. Intraocular pressure (IOP) was measured by using an established microneedle procedure. Outflow facility (C) was determined by constant-pressure perfusion measurements obtained at two different IOPs. Aqueous humor flow (Fa) was determined by a dilution method using rhodamine-dextran. Conventional and uveoscleral outflow (Fc and Fu) were calculated by the Goldmann equation. RESULTS Average IOP, Fa, and C of control eyes were 15.7 +/- 1.0 mm Hg, 0.144 +/- 0.04 microL/min (mean +/- SD, n = 8), and 0.0053 +/- 0.0014 microL/min per mm Hg (n = 21), respectively. Average IOP, Fa, and C of treated eyes were 14.0 +/- 0.8 mm Hg, 0.138 +/- 0.04 microL/min (n = 8 for each), and 0.0074 +/- 0.0016 microL/min per mm Hg (n = 21), respectively. The differences between treated and control eyes were significant for IOP and total outflow facility only. CONCLUSIONS These data indicate that the early hypotensive effect of latanoprost in the mouse eye is associated with a significant increase in total outflow facility. Alterations in the aqueous dynamics induced by latanoprost can be measured reproducibly in the mouse and may provide a useful model for further determining the mechanism by which latanoprost reduces IOP and alters outflow facility.
Weighing physical activity: the impact of a family-based group lifestyle intervention for pediatric obesity on participants' physical activity.

OBJECTIVES To examine differences in self-reported physical activity (PA) between participants enrolled in the treatment versus active control condition of a pediatric obesity intervention, and to test associations between parent and child PA. METHODS Participants (N = 93) included children aged 7-17 years and their parent. Analyses tested whether participants in the treatment condition reported greater PA at postintervention and 12-month follow-up compared with the control condition. Further, researchers examined change in PA across time and whether change in parent PA was associated with change in child PA. RESULTS Children in the treatment condition reported greater PA at 12-month follow-up. Parents in the treatment group reported a significant increase in PA between baseline and postintervention. Change in parent PA was associated with changes in child PA across multiple periods. CONCLUSIONS Family-based obesity interventions may promote long-term change in self-reported PA among youths, and change in parent PA may be a contributing factor.
Sexual Satisfaction in Spanish Heterosexual Couples: Testing the Interpersonal Exchange Model of Sexual Satisfaction

The study of sexual satisfaction in Spain is scarce and has proceeded atheoretically. This study aimed at examining sexual satisfaction in 197 Spanish heterosexual couples based on the Interpersonal Exchange Model of Sexual Satisfaction. Men and women reported equal satisfaction. Men's sexual satisfaction was predicted by their own relationship satisfaction, balance of sexual rewards and costs, and comparison level of sexual rewards and costs. Women's sexual satisfaction was predicted by their own relationship satisfaction, balance of sexual rewards and costs, comparison level of sexual rewards and costs, equality of sexual costs, and their partner's balance of sexual rewards and costs. These results provide with a better understanding of the mechanisms that explain sexual satisfaction in Spanish couples. Implications for research and therapy are discussed.
Prevalent Hallucinations during Medical Internships: Phantom Vibration and Ringing Syndromes

Background Phantom vibration syndrome is a type of hallucination reported among mobile phone users in the general population. Another similar perception, phantom ringing syndrome, has not been previously described in the medical literature. Methods A prospective longitudinal study of 74 medical interns (46 males, 28 females; mean age, 24.8±1.2 years) was conducted using repeated investigations of the prevalence and associated factors of phantom vibration and ringing. The accompanying symptoms of anxiety and depression were evaluated with the Beck Anxiety and Depression Inventories before the internship began, and again at the third, sixth, and twelfth internship months, and two weeks after the internship ended. Results The baseline prevalence of phantom vibration was 78.1%, which increased to 95.9% and 93.2% in the third and sixth internship months. The prevalence returned to 80.8% at the twelfth month and decreased to 50.0% 2 weeks after the internship ended. The baseline prevalence of phantom ringing was 27.4%, which increased to 84.9%, 87.7%, and 86.3% in the third, sixth, and twelfth internship months, respectively. This returned to 54.2% two weeks after the internship ended. The anxiety and depression scores also increased during the internship, and returned to baseline two weeks after the internship. There was no significant correlation between phantom vibration/ringing and symptoms of anxiety or depression. The incidence of both phantom vibration and ringing syndromes significantly increased during the internship, and subsequent recovery. Conclusion This study suggests that phantom vibration and ringing might be entities that are independent of anxiety or depression during evaluation of stress-associated experiences during medical internships.
CyberKnife Radiosurgery for Benign Intradural Extramedullary Spinal Tumors

OBJECTIVE:Microsurgical resection of benign intradural extramedullary spinal tumors is generally safe and successful, but patients with neurofibromatosis, recurrent tumors, multiple lesions, or medical problems that place them at higher surgical risk may benefit from alternatives to surgery. In this prospective study, we analyzed our preliminary experience with image-guided radiosurgical ablation of selected benign spinal neoplasms. METHODS:Since 1999, CyberKnife (Accuray, Inc., Sunnyvale, CA) radiosurgery was used to manage 51 patients (median age, 46 yr; range, 12–86 yr) with 55 benign spinal tumors (30 schwannomas, nine neurofibromas, 16 meningiomas) at Stanford University Medical Center. Total treatment doses ranged from 1600 to 3000 cGy delivered in consecutive daily sessions (1–5) to tumor volumes that varied from 0.136 to 24.6 cm3. RESULTS:Less than 1 year postradiosurgery, three of the 51 patients in this series (one meningioma, one schwannoma, and one neurofibroma) required surgical resection of their tumor because of persistent or worsening symptoms; only one of these lesions was larger radiographically. However, 28 of the 51 patients now have greater than 24 months clinical and radiographic follow-up. After a mean follow-up of 36 months, all of these later lesions were either stable (61%) or smaller (39%). Two patients died from unrelated causes. Radiation-induced myelopathy appeared 8 months postradiosurgery in one patient. CONCLUSION:Although more patients studied over an even longer follow-up period are needed to determine the long-term efficacy of spinal radiosurgery for benign extra-axial neoplasms, short-term clinical benefits were observed in this prospective analysis. The present study demonstrates that CyberKnife radiosurgical ablation of such tumors is technically feasible and associated with low morbidity.
Efficiency Optimization for Burst-Mode Multilevel Radio Frequency Transmitters

The utilization of a burst-mode power amplifier (PA) together with pulse-width modulation (PWM) is a promising concept for achieving high efficiency in radio frequency (RF) transmitters. Nevertheless, such a transmitter architecture requires bandpass filtering to suppress side-band spectral components to retrieve the wanted signal, which reduces the transmit power and the transmitter efficiency. High efficiency can only be expected with the maximum transmit power and signals with low peak-to-average-power ratios (PAPRs). To boost efficiency for signals with high PAPRs and signals at variable transmit power levels, the burst-mode multilevel transmitter architecture has been widely discussed as a potential solution. This paper presents an efficiency optimization procedure of burst-mode multilevel transmitters for signals with high PAPRs and signals at variable transmit power levels. The impact of the threshold value on the transmitter efficiency is studied, where the optimum threshold value and the maximum transmitter efficiency can be obtained according to input magnitude statistics. In addition, the relation between the threshold value and the efficiency expression of burst-mode multilevel transmitters and those of Doherty PAs is investigated. It is shown that the obtained optimum threshold value, although originally designed for burst-mode transmitters, can also be applied to Doherty and multistage Doherty PAs to achieve maximum transmitter efficiency. Simulations are used to validate the efficiency improvement of the optimized burst-mode multilevel transmitters compared to two-level and non-optimized multilevel transmitters.
Ostα−/− mice are not protected from western diet‐induced weight gain

Organic solute transporterα‐OSTβ is a bile acid transporter important for bile acid recycling in the enterohepatic circulation. In comparison to wild‐type mice, Ostα−/− mice have a lower bile acid pool and increased fecal lipids and they are relatively resistant to age‐related weight gain and insulin resistance. These studies tested whether Ostα−/− mice are also protected from weight gain, lipid changes, and insulin resistance which are normally observed with a western‐style diet high in both fat and cholesterol (WD). Wild‐type and Ostα−/− mice were fed a WD, a control defined low‐fat diet (LF) or standard laboratory chow (CH). Surprisingly, although the Ostα−/− mice remained lighter on LF and CH diets, they weighed the same as wild‐type mice after 12 weeks on the WD even though bile acid pool levels remained low and fecal lipid excretion remained elevated. Mice of both genotypes excreted relatively less lipid when switched from CH to LF or WD. WD caused slightly greater changes in expression of genes involved in lipid transport in the small intestines of Ostα−/− mice than wild‐type, but the largest differences were between CH and defined diets. After WD feeding, Ostα−/− mice had lower serum cholesterol and hepatic lipids, but Ostα−/− and wild‐type mice had equivalent levels of muscle lipids and similar responses in glucose and insulin tolerance tests. Taken together, the results show that Ostα−/− mice are able to adapt to a western‐style diet despite low bile acid levels.
Intensity-Modulated Radiation Therapy with Stereotactic Body Radiation Therapy Boost for Unfavorable Prostate Cancer: The Georgetown University Experience

Purpose/objective(s) Stereotactic body radiation therapy (SBRT) is emerging as a minimally invasive alternative to brachytherapy to deliver highly conformal, dose-escalated radiation therapy (RT) to the prostate. SBRT alone may not adequately cover the tumor extensions outside the prostate commonly seen in unfavorable prostate cancer. External beam radiation therapy (EBRT) with high dose rate brachytherapy boost is a proven effective therapy for unfavorable prostate cancer. This study reports on early prostate-specific antigen and prostate cancer-specific quality of life (QOL) outcomes in a cohort of unfavorable patients treated with intensity-modulated radiation therapy (IMRT) and SBRT boost. Materials/methods Prostate cancer patients treated with SBRT (19.5 Gy in three fractions) followed by fiducial-guided IMRT (45–50.4 Gy) from March 2008 to September 2012 were included in this retrospective review of prospectively collected data. Biochemical failure was assessed using the Phoenix definition. Patients completed the expanded prostate cancer index composite (EPIC)-26 at baseline, 1 month after the completion of RT, every 3 months for the first year, then every 6 months for a minimum of 2 years. Results One hundred eight patients (4 low-, 45 intermediate-, and 59 high-risk) with median age of 74 years completed treatment, with median follow-up of 4.4 years. Sixty-four percent of the patients received androgen deprivation therapy prior to the initiation of RT. The 3-year actuarial biochemical control rates were 100 and 89.8% for intermediate- and high-risk patients, respectively. At the initiation of RT, 9 and 5% of men felt their urinary and bowel function was a moderate to big problem, respectively. Mean EPIC urinary and bowel function and bother scores exhibited transient declines, with subsequent return to near baseline. At 2 years posttreatment, 13.7 and 5% of men felt their urinary and bowel function was a moderate to big problem, respectively. Conclusion At 3-year follow-up, biochemical control was favorable. Acute urinary and bowel symptoms were comparable to conventionally fractionated IMRT and brachytherapy. Patients recovered to near their baseline urinary and bowel function by 2 years posttreatment. A combination of IMRT with SBRT boost is well tolerated with minimal impact on prostate cancer-specific QOL.
KEJADIAN BERAT BADAN LAHIR RENDAH DI DESA TINELO KABUPATEN GORONTALO DAN FAKTOR YANG MEMENGARUHINYA

ABSTRACT The aim of this study was to assess the association of maternal age, education level and family income with low birth weight (LBW). The study was an observational study with cross sectional design. The number of subject were 60 children under five years old obtained by accidental sampling. The results showed that 18.3% of mothers gave birth at high risk age (≤19 years old and ≥35 years old), 43.3% mothers had education level of senior high school, 96.7% mothers were housewives, 54.2% father’s occupation was self-employed, 71.7% of family income per month was under minimum regional wage. 16.7% of infants with LBW. The bivariate analysis showed that the incidence of low birth weight was not associated with maternal age (p=0.371), there was no correlation between the incidence of low birth weight with family income per month (p=0.709) and there was correlation between low birth weight with mother education level (p=0.017). It can be concluded that maternal age and family income per month was not associated with LBW, while education level was associated with LBW. Keywords: education, income, low birth weight, maternal age ABSTRAK Penelitian ini bertujuan menilai hubungan usia ibu melahirkan, pendidikan dan pendapatan dengan kejadian berat badan lahir rendah (BBLR). Jenis penelitian adalah observasional dengan rancangan studi potong lintas. Jumlah subjek dalam penelitian ini adalah 60 balita diperoleh dengan cara accidental sampling. Hasil penelitian menunjukkan bahwa 18,3% ibu melahirkan pada usia berisiko (≤19 tahun dan ≥35 tahun), 43,3% tingkat pendidikan ibu balita adalah Sekolah Menengah Pertama, 96,7% merupakan ibu rumah tangga, 54,2% pekerjaan ayah sebagai wiraswasta, 71,7% pendapatan keluarga per bulan dibawah upah minimum regional. Jumlah balita BBLR 16,7%. Analisis bivariat menunjukkan kejadian BBLR tidak berhubungan dengan umur ibu melahirkan (p=0,371), tidak terdapat hubungan antara kejadian BBLR dengan pendapatan per bulan (p=0,709), terdapat hubungan antara BBLR dengan tingkat pendidikan ibu (p=0,017). Kesimpulan tidak ditemukan hubungan usia ibu hamil dan pendapatan keluarga per bulan dengan BBLR, sementara tingkat pendidikan berhubungan dengan kejadian BBLR. Kata kunci: BBLR, pendapatan, pendidikan, umur ibu
Real time motion generation and control for biped robot -2nd report: Running gait pattern generation-

Bipedal running can easily result in a fall due to poor availability of the ground reaction force at the boundary of the flight and support phases. We propose methods to decompose and synthesize a running gait pattern into vertical, horizontal and rotational components so that time-dependent ground friction limits are satisfied. We also extend previously proposed boundary condition, the divergent component of motion, for switching walking gait patterns into running which involves vertical acceleration of the center of gravity. Using these techniques, running at 10 km/h is achieved on a real robot whose dimension are same as ASIMO.
Perception of Professional Female College Students Towards Smile arc Types and Outlook about their Appearance

Aims and Objectives: The aim of this study is to assess the perception of female students about the type of smile arc as well as their outlook about different parameters of esthetics. Materials and Methods: A study was conducted among female students of King Khalid University, Abha, Saudi Arabia. One section of the questionnaire contained pictures having three types of smile arc wherein the respondents had to select any response ranging from 1 to 4 (1 for beautiful, 2 for good, 3 for average, and 4 for poor); besides it included 12 questions regarding the viewpoints of respondents about their smile and dental esthetics. The collected data were analyzed using the statistical package for social services version 16.0 (SPSS Inc., Chicago, IL, USA, 2001). Results: The dental students accounted for least mean score of 1.807 ± 0.8174 for consonant smile arc while it was 2.692 ± 0.8053 and 2.235 ± 0.9074 for information technology (IT) and medical students, respectively. When the individuals were asked whether they had a pleasant smile or not; only 53.8% of the dental students, 76.9% of the IT students, and 66.7% of the medical students responded positively. Conclusion: It was concluded that most of the female dental students were able to identify the consonant smile arc as being more beautiful than the flat and reverse smile arcs whereas lesser medical and IT students could perceive the smile arcs in the same manner. It was also observed that almost all the study participants were quite conscious about their smile attractiveness and dental esthetics.
Neuroscience and Biobehavioral Reviews How Does Visual Language Affect Crossmodal Plasticity and Cochlear Implant Success?

Cochlear implants (CI) are the most successful intervention for ameliorating hearing loss in severely or profoundly deaf children. Despite this, educational performance in children with CI continues to lag behind their hearing peers. From animal models and human neuroimaging studies it has been proposed the integrative functions of auditory cortex are compromised by crossmodal plasticity. This has been argued to result partly from the use of a visual language. Here we argue that 'cochlear implant sensitive periods' comprise both auditory and language sensitive periods, and thus cannot be fully described with animal models. Despite prevailing assumptions, there is no evidence to link the use of a visual language to poorer CI outcome. Crossmodal reorganisation of auditory cortex occurs regardless of compensatory strategies, such as sign language, used by the deaf person. In contrast, language deprivation during early sensitive periods has been repeatedly linked to poor language outcomes. Language sensitive periods have largely been ignored when considering variation in CI outcome, leading to ill-founded recommendations concerning visual language in CI habilitation.