Miracle-dz/UniFAR-FTUs huggingface dataset:
Stokes shift spectroscopic analysis of multifluorophores for human cancer detection in breast and prostate tissues

Abstract. Stokes shift spectroscopy (S3) offers a novel and simpler way to rapidly recognize spectral fingerprints of multiple fluorophores in complex media such as in tissue. This spectroscopic technique can be used as an effective approach to detect cancer in tissue. The alterations of the measured S3 spectra between cancerous and normal tissues were observed in human breast and prostate samples. In order to obtain the optimal Stokes shift interval, Δλi, for the purpose of breast/prostate cancer detection using S3, the S3 spectra of a mixed aqueous solution of tryptophan, nicotinamide adenine dinucleotide, and flavin were measured with different Δλi values. The experimental results analyzed using nonnegative least square method show that there is a reduced contribution from collagen and an increased contribution from tryptophan to the S3 signal of the cancerous tissue as compared with those of the normal tissue. This study indicates that the changes of relative contents of tryptophan and collagen in tissue shown by the S3 spectra may present potential native biomarkers for breast and prostate cancer detection. S3 has the potential to be a new armamentarium.
Effect of limestone particle size on egg production and eggshell quality of hens during late production

A study was conducted to determine the influence of different particle size limestone in layer diets on egg production and eggshell quality during the later stages of egg production (>54 weeks of age). Calcitic limestone (360 g Ca/kg), consisting of small ( 2+ to laying hens for egg production and eggshell quality at end-of-lay, provided that the dietary Ca content satisfies the requirements of the laying hen.
Rheology of Foaming Polymers and Its Influence on Microcellular Processing

The rheological properties of polymer melts and polymer/blowing agent (BA) solutions are determined experimentally and the influences of material rheological properties and crystallization on low-density foaming behaviour of polylactic acid (PLA) are investigated. Understanding the rheological properties of foaming polymers allows the optimization of polymer chemical structure and the development of technologies that produce desired cell morphologies. Although the technology for producing CO2-blown polystyrene (PS) foams is well established, the rheological properties of a PS/CO2 solution, especially its extensional property, are not well understood. In this study, these properties are determined with an in-house developed, online technique, and the measured data are compared with those from commercial rheometers. The online measurement system consists of a tandem foam extrusion system and a die for measuring pressure drops. Shear viscosity is determined from the pressure drop over a straight rectangular channel, while planar extensional viscosity from the pressure drop over a thin hyperbolic channel, taking into account the pressure drop due to shearing. Measured viscosities of the polystyrene without CO2 compare well with those from commercial rheometers. With the presence of dissolved CO2, both the shear and extensional viscosities of the polystyrene are significantly reduced. The influence of CO2 on the two viscosities is found to be similar to an increase of temperature.Polylactic acid is the first mass-produced biodegradable polymer, and has potential to replace petroleum-based polymers in foaming applications. In this study, the influences of material rheological properties and crystallization on the low-density, microcellular extrusion foaming behaviour of polylactic acids (PLAs) are investigated. Comparisons are made between linear and branched PLAs and between amorphous and crystalline PLAs. The branched PLAs are found to produce foams with higher expansion ratios and reduced open-cell content compared to the linear PLA. The foaming behaviour of the linear PLA, then, is significantly improved by adding a small amount of long-chain-branched PLA. The improved cell structure with branched PLAs is attributed to their relatively high melt strength and strain to break. For the first time, it is shown that crystallization, induced by cooling and macroscopic flow during processing, increases melt strength, which aids the production of low-density foams.
Father Involvement in Parent Training: When Does It Matter?

We examined the impact of father involvement on treatment. Participants were 107 families enrolled in parent-child interaction therapy (PCIT), including 56 involved-father (IF) families, 16 uninvolved-father (UF) families, and 35 absent-father (AF) families. All groups showed improvements during treatment to within the average range on the Eyberg Child Behavior Inventory (ECBI), although mothers from AF families reported better treatment outcome than mothers from IF families. Improvements occurred on the Beck Depression Inventory (BDI) and the Parenting Stress Index (PSI) as well, but there were no group differences. At a 4-month follow-up, mothers in IF families maintained treatment gains on the ECBI. In contrast, mothers in AF families reported significant decline at follow-up, although their scores remained within the normal range. Results suggest that father participation in treatment may not affect immediate treatment outcome but may help to maintain the beneficial effects of PCIT.
Polynomial Networks and Factorization Machines: New Insights and Efficient Training Algorithms

Polynomial networks and factorization machines are two recently-proposed models that can efficiently use feature interactions in classification and regression tasks. In this paper, we revisit both models from a unified perspective. Based on this new view, we study the properties of both models and propose new efficient training algorithms. Key to our approach is to cast parameter learning as a low-rank symmetric tensor estimation problem, which we solve by multi-convex optimization. We demonstrate our approach on regression and recommender system tasks.
On sequences of positive integers

Let a 1 , a 2 ,. , a m be any finite set of distinct natural numbers, and let b 1 , b 2 ,. be the sequence formed by all those numbers which are divisible by any of a 1 , a 2 . , a m . This sequence has a density in the obvious sense and we denote this density by A(a 1 a 2 ,.a m ).
STABILIZATION OF SOUTH TEXAS SOILS WITH FLY ASH

The expansive soils of south Texas have traditionally been stabilized with lime or Portland cement. As an alternative, a class F fly ash was tried to stabilize expansive soils obtained from within or the vicinity of Kleberg County in south Texas. Three groups of soils samples were made. The first group was stabilized with 20% by dry weight of Class F fly ash, the second group with 6% lime, and the third group with 10 % Portland cement. The purpose of lime and cement stabilized samples was to have a basis of comparison for the effectiveness of fly ash stabilization. Methods used to evaluate the effectiveness of stabilization included grain size, plasticity index, unconfined compressive strength, and scanning electron microscopy. Laboratory test results showed that fly ash, lime, and cement stabilization were all effective in ameliorating the texture and plasticity of the soils by reducing the amount of clay sized particles and the plasticity index. Portland cement was more effective followed by lime and fly ash stabilization in changing the texture and plasticity of the soils
The serum concentration of magnesium as a potential state marker in patients with diagnosis of bipolar disorder.

AIM Few scientific reports indicate changes in the concentration of magnesium in the blood of patients with bipolar disorder (BD). So far very little studies concerning these issues have been conducted. Therefore, the aim of this study was to evaluate the serum magnesium level in patients with bipolar disorder (in different phases of the disease) in comparison to healthy volunteers. METHODS The study included 129 patients (58 subjects in depressive episode, 23 in manic episode and 48 patients in remission) with the diagnosis of bipolar disorder type I or II. The control group consisted of 50 healthy people. Magnesium concentration was measured using flame atomic absorption spectrometry (FAAS). RESULTS Patients with a current depressive or manic/hypomanic episode had statistically significantly elevated serum magnesium levels compared to healthy volunteers. Moreover, a positive correlation between the duration of the manic/hypomanic episode and the relapse frequency in the last year was observed. The concentration of magnesium in patients in remission was unchanged in relation to the control group. CONCLUSIONS Presented findings suggest a role of serum magnesium level as a potential state marker, reflecting the pathophysiological changes associated with acute episodes of bipolar disorder.
Filling the blanks in temporal intervals: the type of filling influences perceived duration and discrimination performance

In this work we investigate how judgments of perceived duration are influenced by the properties of the signals that define the intervals. Participants compared two auditory intervals that could be any combination of the following four types: intervals filled with continuous tones (filled intervals), intervals filled with regularly-timed short tones (isochronous intervals), intervals filled with irregularly-timed short tones (anisochronous intervals), and intervals demarcated by two short tones (empty intervals). Results indicate that the type of intervals to be compared affects discrimination performance and induces distortions in perceived duration. In particular, we find that duration judgments are most precise when comparing two isochronous and two continuous intervals, while the comparison of two anisochronous intervals leads to the worst performance. Moreover, we determined that the magnitude of the distortions in perceived duration (an effect akin to the filled duration illusion) is higher for tone sequences (no matter whether isochronous or anisochronous) than for continuous tones. Further analysis of how duration distortions depend on the type of filling suggests that distortions are not only due to the perceived duration of the two individual intervals, but they may also be due to the comparison of two different filling types.
Behavioral Study of Users When Interacting with Active Honeytokens

Active honeytokens are fake digital data objects planted among real data objects and used in an attempt to detect data misuse by insiders. In this article, we are interested in understanding how users (e.g., employees) behave when interacting with honeytokens, specifically addressing the following questions: Can users distinguish genuine data objects from honeytokens? And, how does the user's behavior and tendency to misuse data change when he or she is aware of the use of honeytokens? First, we present an automated and generic method for generating the honeytokens that are used in the subsequent behavioral studies. The results of the first study indicate that it is possible to automatically generate honeytokens that are difficult for users to distinguish from real tokens. The results of the second study unexpectedly show that users did not behave differently when informed in advance that honeytokens were planted in the database and that these honeytokens would be monitored to detect illegitimate behavior. These results can inform security system designers about the type of environmental variables that affect people's data misuse behavior and how to generate honeytokens that evade detection.
Face sketch recognition by Local Radon Binary Pattern: LRBP

In this paper, we propose a new face descriptor to directly match face photos and sketches of different modalities, called Local Radon Binary Pattern (LRBP). LRBP is inspired by the fact that the shape of a face photo and its corresponding sketch is similar, even when the sketch is exaggerated by an artist. Therefore, the shape of face can be exploited to compute features which are robust against modality differences between face photo and sketch. In LRBP framework, the characteristics of face shape are captured by transforming face image into Radon space. Then, micro-information of face shape in new space is encoded by Local Binary Pattern (LBP). Finally, LRBP is computed by concatenating histograms of local LBPs. In order to capture both local and global characteristics of face shape, LRBP is extracted in a spatial pyramid fashion. Experiments on CUFS and CUFSF datasets indicate the efficiency of LRBP for face sketch recognition.
A compression algorithm for DNA sequences and its applications in genome comparison

We present a lossless compression algorithm, <italic>Gen-Compress</italic>, for DNA sequences, based on searching for approximate repeats. Our algorithm achieves the best compression ratios for benchmark DNA sequences, comparing to other DNA compression programs [3, 7]. Significantly better compression results show that the approximate repeats are one of the main hidden regularities in DNA sequences. We then describe a theory of measuring the relatedness between two DNA sequences. We propose to use <italic>d</italic>(<italic>x</italic>, <italic>y</italic>) = 1 — <italic>K</italic>(<italic>x</italic>) - <italic>K</italic>(<italic>x</italic>|<italic>y</italic>)/<italic>K</italic>(<italic>xy</italic> to measure the distance of any two sequences, where <italic>K</italic> stands for Kolmogorov complexity [5]. Here, <italic>K</italic>(<italic>x</italic>) - <italic>K</italic>(<italic>x</italic>|<italic>y</italic>) is the mutual information shared by <italic>x</italic> and <italic>y</italic>. But mutual information is not a distance, there is no triangle inequality. The distance <italic>d</italic>(<italic>x</italic>, <italic>y</italic>) is symmetric. It also satisfies the triangle inequality, and furthermore, it is universal [4]. It has not escaped our notice that the distance measure we have postulated can be immediately used to construct evolutionary trees from DNA sequences, especially those that cannot be aligned, such as complete genomes. With more and more genomes sequenced, constructing trees from genomes becomes possible [1, 2, 6, 8]. Kolmogorov complexity is not computable. We use <italic>GenCompress</italic> to approximate it. We present strong experimental support for this theory, and demonstrate its applicability by correctly constructing a 16S (18S) rRNA tree, and a whole genome tree for several species of bacteria. Larger scale experiments are underway at the University of Waterloo, with very promising results.
Critical [Formula: see text] of skeletal muscle in vivo.

The main purpose of this study was to determine the interstitial oxygen tension at which aerobic metabolism becomes limited (critical [Formula: see text]) in vivo in resting skeletal muscle. Using an intravital microscope system, we determined the interstitial oxygen tension at 20-μm-diameter tissue sites in rat spinotrapezius muscle from the phosphorescence lifetime decay of a metalloporphyrin probe during a 1-min stoppage of muscle blood flow. In paired experiments NADH fluorescence was measured at the same sites during flow stoppage. NADH fluorescence rose significantly above control when interstitial[Formula: see text] fell to 2.9 ± 0.5 mmHg ( n = 13) and was not significantly different (2.4 ± 0.5 mmHg) when the two variables were first averaged for all sites and then compared. Similar values were obtained using the abrupt change in rate of[Formula: see text] decline as the criterion for critical [Formula: see text]. With a similar protocol, we determined that NADH rose significantly at a tissue site centered 30 μm from a collecting venule when intravascular[Formula: see text] fell to 7.2 ± 1.5 mmHg. The values for critical interstitial and critical intravascular[Formula: see text] are well below those reported during free blood flow in this and in other muscle preparations, suggesting that oxygen delivery is regulated at levels well above the minimum required for oxidative metabolism. The extracellular critical[Formula: see text] found in this study is slightly greater than previously found in vitro, possibly due to differing local conditions rather than a difference in metabolic set point for the mitochondria.
Vestibular processing in human paramedian precuneus as shown by electrical cortical stimulation

The authors describe a 16-year-old patient with recurrent episodes of epileptic linear self-motion perception and occasional body tilts. Intracranial seizure monitoring located the seizure onset, caused by a circumscribed ependymoma, in the right paramedian precuneus. Electrical cortical stimulation of this area could reproduce the same vestibular sensations, which ceased after lesionectomy. The findings implicate the paramedian area of the precuneus in the processing of static and dynamic vestibular, probably otolithic, information.
Effects of Applied Training Loads on the Aerobic Capacity of Young Soccer Players During a Soccer Season

Abstract Jastrzębski, Z, Rompa, P, Szutowicz, M, and Radzimiński, L. Effects of applied training loads on the aerobic capacity of young soccer players during a soccer season. J Strength Cond Res 27(4): 916–923, 2013—The aim of this study was to examine the effects of applied training loads on the aerobic capacity, speed, power, and speed endurance of young soccer players during 1 soccer season. The participants in the study were 19 young male soccer players (age: 16.61 ± 0.31 years; weight: 64.28 ± 6.42 kg; height: 176.58 ± 5.98 cm). The players completed 150 training sessions and 54 games over the course of 1 soccer season. The training intensity was divided into 4 categories: (a) aerobic performance (61% of the total training duration), (b) mixed aerobic-anaerobic performance (34%), (c) anaerobic lactate performance (3%), and (d) anaerobic nonlactate performance (2%). No significant changes in the V[Combining Dot Above]O2max were observed throughout the season. The players' power level and speed endurance increased significantly with the coincident decrements in their 5-m sprint time. The applied training loads, including 1 high-intensity training session of small-sided games performed during a competitive season, did not significantly change the aerobic capacity of the young soccer players. However, the participants did maintain their V[Combining Dot Above]O2max at the elite level. The first squad players (FSPs) reached the highest level of aerobic fitness in the middle of the season, whereas substitute players (SPs) at the end of the season. Moreover, the V[Combining Dot Above]O2max in FSP was significantly higher (p < 0.003) than in SP in the middle of the season.
Sound: a non-invasive measure of cough intensity

Introduction Cough intensity is an important determinant of cough severity reported by patients. Cough sound analysis has been widely validated for the measurement of cough frequency but few studies have validated its use in the assessment of cough strength. We investigated the relationship between cough sound and physiological measures of cough strength. Methods 32 patients with chronic cough and controls underwent contemporaneous measurements of voluntary cough sound, flow and oesophageal pressure. Sound power, peak energy, rise-time, duration, peak-frequency, bandwidth and centroid-frequency were assessed and compared with physiological measures. The relationship between sound and subjective cough strength Visual Analogue Score (VAS), the repeatability of cough sounds and the effect of microphone position were also assessed. Results Sound power and energy correlated strongly with cough flow (median Spearman’s r=0.87–0.88) and oesophageal pressure (median Spearman’s r=0.89). Sound power and energy correlated strongly with cough strength VAS (median Spearman’s r=0.84–0.86) and were highly repeatable (intraclass correlation coefficient=0.93–0.94) but both were affected by change in microphone position. Conclusions Cough sound power and energy correlate strongly with physiological measures and subjective perception of cough strength. Power and energy are highly repeatable measures but the microphone position should be standardised. Our findings support the use of cough sound as an index of cough strength.
Leading Edge of a Hydraulic Fracture Crossing a Stress Boundary

The presence of stress and material interfaces in hydrocarbon reservoirs may significantlycomplicate prediction of hydraulic fracture propagation, as the spatial resolution of numericalcodes is usually insufficient to capture the details of the fracture-interface interactionat the early stages of the crossing. Thus, an explicit analytical and experimental investigationof the leading edge of the fracture normally crossing a stress interface (where thestress component normal to the fracture plane is discontinuous) is undertaken under conditionswhen solid toughness, fluid leak-off, and fluid lag are negligible. The analytical planestrain solution corresponds to that of a semi-infinite hydraulic fracture, which propagationvelocity varies with the penetration depth past the interface. When appropriately scaled,the solution depends on a single dimensionless penetration depth parameter or time. Comparisonwith the experimental results for initially penny-shape hydraulic fractures crossinga stress interface in PMMA shows remarkable agreement in a wide range of penetrationvalues.
The Impact of Movements and Animal Density on Continental Scale Cattle Disease Outbreaks in the United States

Globalization has increased the potential for the introduction and spread of novel pathogens over large spatial scales necessitating continental-scale disease models to guide emergency preparedness. Livestock disease spread models, such as those for the 2001 foot-and-mouth disease (FMD) epidemic in the United Kingdom, represent some of the best case studies of large-scale disease spread. However, generalization of these models to explore disease outcomes in other systems, such as the United States’s cattle industry, has been hampered by differences in system size and complexity and the absence of suitable livestock movement data. Here, a unique database of US cattle shipments allows estimation of synthetic movement networks that inform a near-continental scale disease model of a potential FMD-like (i.e., rapidly spreading) epidemic in US cattle. The largest epidemics may affect over one-third of the US and 120,000 cattle premises, but cattle movement restrictions from infected counties, as opposed to national movement moratoriums, are found to effectively contain outbreaks. Slow detection or weak compliance may necessitate more severe state-level bans for similar control. Such results highlight the role of large-scale disease models in emergency preparedness, particularly for systems lacking comprehensive movement and outbreak data, and the need to rapidly implement multi-scale contingency plans during a potential US outbreak.