Miracle-dz/UniFAR-FTUs huggingface dataset:
User Acceptance of Agile Information Systems: A Model and Empirical Test

In response to the rapid changes in users' requirements, a new generation of information systems (IS), namely, agile IS, has emerged. Agile IS, defined as information systems developed using agile methods, are characterized by frequent upgrades with a small number of new features released periodically. The existing research on agile IS has mainly focused on the developers' perspective with little research into end users' responses to these agile IS. Drawing upon the tripartite model of attitude, the status quo and the omission bias theories, and the availability heuristic, we propose a model that utilizes constructs from the unified theory of acceptance and use of technology, the IS continuance model, habit, and individual differences to examine the drivers of user acceptance of agile IS. Further, we investigate not only users' intentions to continue using the agile IS but also their intentions to use new features when they are released, which is a surrogate for the ultimate success of agile IS. Data from 477 users of an agile IS showed that users' level of comfort with constant changes, the facilitating conditions provided, and users' habit are predictors of both types of intentions, with users' level of comfort with constant changes being the strongest predictor. Users' intentions to continue using agile IS are also determined by users' satisfaction with and perceived usefulness of the past upgrades. Finally, users who are innovative are more likely to use future releases of new features. The present work fills a gap in the software engineering literature and contributes a technology acceptance model specific to agile IS, which are becoming a mainstay of companies' IT portfolio in a fast-changing business environment.
Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection

The replication and transcriptional activator (Rta), encoded by ORF50 of gammaherpesviruses, initiates the lytic cycle of gene expression; therefore understanding the impact of Rta on viral and cellular gene expression is key to elucidating the transcriptional events governing productive infection and reactivation from latency. To this end, the impact of altering Rta transcription on viral and cellular gene expression was studied in the context of a whole virus infection. Recombinant murine gammaherpesvirus (MHV)-68 engineered to overexpress Rta greatly accelerated expression of specific lytic cycle ORFs, but repressed transcription of the major latency gene, ORF73. Increased expression of Rta accelerated the dysregulation in transcription of specific cellular genes when compared with cells infected with wild-type and revertant viruses. A subset of cellular genes was dysregulated only in cells infected with Rta-overexpressing virus, and never in those infected with non-overexpressing viruses. These data highlight the critical role of Rta abundance in governing viral and cellular gene transcription, and demonstrate the importance of understanding how the relative expression of ORF50 during the virus life cycle impacts on these processes.
Thermal and albedo mapping of Mars during the Viking primary mission

Measurements of Martian emission and reflection reveal wide variations of surface properties and indicate the presence of a larger atmospheric contribution to the observed radiances than was anticipated. Temperatures observed during the Viking primary mission range from 130 to 290 K. Surface thermal inertias from 1.6 to 11×10−3 cal cm−2 s−1/2 K−1 are mapped, and they correlate with surficial geologic units. An equatorial map of bolometric albedo generally correlates with prior narrowband observations. These albedos range from 0.09 to 0.43; some regional brightenings are atmospheric in origin. The photometric behavior implies quasi-Lambertian surface reflectance plus a strongly forward-scattering atmosphere. Brightness temperatures at large emission angles are strongly influenced by atmospheric infrared opacity and by the presence of rocks on the surface. The correlation and grouping of albedo and thermal inertia indicate that there are two major components of Martian surface material, with bright regions having a fine particulate covering. Winter polar temperatures show spatial and temporal variations, suggesting variation of atmospheric composition; a strong atmospheric temperature inversion exists above the south polar cap during winter. Surface CO2 condensation may also occur locally near the equator before dawn. Rising temperatures before dawn in a region near Arsia Mons imply the presence of daily local water ice fogs.
Youngest reported radiocarbon age of a moa (Aves: Dinornithiformes) dated from a natural site in New Zealand

Abstract The extinction date of the giant flightless New Zealand ratite bird, the crested moa (Pachyornis australis), is of considerable interest because the youngest verified remains are dated to the Pleistocene–Holocene transition c. 10,000 yr BP, which was characterised by severe climatic and habitat change, and are considerably earlier than the late Holocene extinctions of the other eight moa species. Analysis of a partial crested moa skeleton (NMNZ S23569) from Castle Keep Entrance, Bulmer Cave System, Mount Owen, South Island, generated a radiocarbon date of 564±26 yr BP (544–508 cal yr BP; 95.4% AD 1396–1442). As a result the Bulmer Cave specimen represents the youngest moa yet found from a natural site in New Zealand. Combined with additional crested moa remains dated to the late Holocene from Cheops Cave (Mount Arthur) and Magnesite Quarry (Cobb Valley), this indicates that crested moa did not go extinct during the Pleistocene–Holocene transition but survived until after Polynesian colonisation in c. AD 1280. The new radiocarbon dates reported here have important implications for the timing of moa extinction and the late survival of moa in alpine areas of New Zealand.
Parallel eigenvalue reordering in real Schur forms

A parallel algorithm for reordering the eigenvalues in the real Schur form of a matrix is presented and discussed. Our novel approach adopts computational windows and delays multiple outside‐window updates until each window has been completely reordered locally. By using multiple concurrent windows the parallel algorithm has a high level of concurrency, and most work is level 3 BLAS operations. The presented algorithm is also extended to the generalized real Schur form. Experimental results for ScaLAPACK‐style Fortran 77 implementations on a Linux cluster confirm the efficiency and scalability of our algorithms in terms of more than 16 times of parallel speedup using 64 processors for large‐scale problems. Even on a single processor our implementation is demonstrated to perform significantly better compared with the state‐of‐the‐art serial implementation. Copyright © 2009 John Wiley & Sons, Ltd.
Geochronology of high‐pressure mafic granulite dykes in SW Sweden: tracking the P–T–t path of metamorphism using Hf isotopes in zircon and baddeleyite

Although the U–Pb zircon chronometer has been widely used for dating metamorphism in moderate‐ to high‐grade rocks, it is generally difficult to link the U–Pb age of zircon to specific metamorphic reactions. In this study, the initial Hf isotopic composition of secondary zircon is compared with the evolution of Hf isotopic composition of the bulk sample, back‐projected from the measured value through time. This approach may enhance the interpretation of radiometric ages performed on metamorphic mineral assemblages. Here, U–Pb, Sm–Nd and Lu–Hf geochronology and thermobarometry have been integrated and applied to two metamorphosed diabase dykes in the Sveconorwegian orogen, SW Sweden. The dykes are located ∼5 km east of the NNE‐trending Göta Älv deformation zone in the Idefjorden terrane, and trend parallel to this zone. The Lunden dyke is recrystallized into a coronitic, granulite facies assemblage. U–Pb isotopic analyses of baddeleyite in this dyke indicate an emplacement age of c. 1300 Ma. Thermobarometric techniques applied to garnet and omphacitic clinopyroxene coronas indicate high‐pressure metamorphism at ∼15 kbar and ∼740 °C. The growth of polycrystalline zircon at the expense of baddeleyite occurred at 1046 ± 6 Ma. The identical Hf isotopic composition of polycrystalline zircon and baddeleyite shows that the baddeleyite‐to‐zircon transition took place before Hf equilibration among the other metamorphic minerals and, hence the c. 1046 Ma age of polycrystalline zircon sets an upper age limit of metamorphism of this sample. The Haregården dyke is recrystallized into a granoblastic transitional upper amphibolite to granulite facies assemblage. The estimated P–T conditions are ∼10 kbar and ∼700 °C. Analyses of small (∼30 μm), clear and round zircon in this sample yield a Concordia U–Pb age of 1026 ± 4 Ma, which is indistinguishable from the Lu‐Hf and Sm‐Nd mineral isochron ages of 1027 ± 9 and 1022 ± 34 Ma, respectively. This type of secondary zircon plots at the lower end of the Lu‐Hf isochron and indicates simultaneous growth with garnet at c. 1026 Ma, a time when Hf isotopic equilibrium among minerals must have been reached.
Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease

Treatment of Buruli ulcer, or Mycobacterium ulcerans disease, has shifted from surgical excision and skin grafting to antibiotic therapy usually with 8 weeks of daily rifampin (RIF) and streptomycin (STR). Although the results have been highly favorable, administration of STR requires intramuscular injection and carries the risk of side effects, such as hearing loss. Therefore, an all-oral, potentially less toxic, treatment regimen has been sought and encouraged by the World Health Organization. A combination of RIF plus clarithromycin (CLR) has been successful in patients first administered RIF+STR for 2 or 4 weeks. Based on evidence of efficacy of clofazimine (CFZ) in humans and mice with tuberculosis, we hypothesized that the combination of RIF+CFZ would be effective against M. ulcerans in the mouse footpad model of M. ulcerans disease because CFZ has similar MIC against M. tuberculosis and M. ulcerans. For comparison, mice were also treated with the gold standard of RIF+STR, the proposed RIF+CLR alternative regimen, or CFZ alone. Treatment was initiated after development of footpad swelling, when the bacterial burden was 4.64±0.14log10 CFU. At week 2 of treatment, the CFU counts had increased in untreated mice, remained essentially unchanged in mice treated with CFZ alone, decreased modestly with either RIF+CLR or RIF+CFZ, and decreased substantially with RIF+STR. At week 4, on the basis of footpad CFU counts, the combination regimens were ranked as follows: RIF+STR>RIF+CLR>RIF+CFZ. At weeks 6 and 8, none of the mice treated with these regimens had detectable CFU. Footpad swelling declined comparably with all of the combination regimens, as did the levels of detectable mycolactone A/B. In mice treated for only 6 weeks and followed up for 24 weeks, there were no relapses in RIF+STR treated mice, one (5%) relapse in RIF+CFZ-treated mice, but >50% in RIF+CLR treated mice. On the basis of these results, RIF+CFZ has potential as a continuation phase regimen for treatment of M. ulcerans disease.
Effect of exercise training on Ca2+ release units of left ventricular myocytes of spontaneously hypertensive rats

In cardiomyocytes, calcium (Ca2+) release units comprise clusters of intracellular Ca2+ release channels located on the sarcoplasmic reticulum, and hypertension is well established as a cause of defects in calcium release unit function. Our objective was to determine whether endurance exercise training could attenuate the deleterious effects of hypertension on calcium release unit components and Ca2+ sparks in left ventricular myocytes of spontaneously hypertensive rats. Male Wistar and spontaneously hypertensive rats (4 months of age) were divided into 4 groups: normotensive (NC) and hypertensive control (HC), and normotensive (NT) and hypertensive trained (HT) animals (7 rats per group). NC and HC rats were submitted to a low-intensity treadmill running protocol (5 days/week, 1 h/day, 0% grade, and 50-60% of maximal running speed) for 8 weeks. Gene expression of the ryanodine receptor type 2 (RyR2) and FK506 binding protein (FKBP12.6) increased (270%) and decreased (88%), respectively, in HC compared to NC rats. Endurance exercise training reversed these changes by reducing RyR2 (230%) and normalizing FKBP12.6 gene expression (112%). Hypertension also increased the frequency of Ca2+ sparks (HC=7.61±0.26 vs NC=4.79±0.19 per 100 µm/s) and decreased its amplitude (HC=0.260±0.08 vs NC=0.324±0.10 ΔF/F0), full width at half-maximum amplitude (HC=1.05±0.08 vs NC=1.26±0.01 µm), total duration (HC=11.51±0.12 vs NC=14.97±0.24 ms), time to peak (HC=4.84±0.06 vs NC=6.31±0.14 ms), and time constant of decay (HC=8.68±0.12 vs NC=10.21±0.22 ms). These changes were partially reversed in HT rats (frequency of Ca2+ sparks=6.26±0.19 µm/s, amplitude=0.282±0.10 ΔF/F0, full width at half-maximum amplitude=1.14±0.01 µm, total duration=13.34±0.17 ms, time to peak=5.43±0.08 ms, and time constant of decay=9.43±0.15 ms). Endurance exercise training attenuated the deleterious effects of hypertension on calcium release units of left ventricular myocytes.
Large increase in dissolved inorganic carbon flux from the Mississippi River to Gulf of Mexico due to climatic and anthropogenic changes over the 21st century

It is recognized that anthropogenic factors have had a major impact on carbon fluxes from land to the ocean during the past two centuries. However, little is known about how future changes in climate, atmospheric CO2, and land use may affect riverine carbon fluxes over the 21st century. Using a coupled hydrological‐biogeochemical model, the Dynamic Land Ecosystem Model, this study examines potential changes in dissolved inorganic carbon (DIC) export from the Mississippi River basin to the Gulf of Mexico during 2010–2099 attributable to climate‐related conditions (temperature and precipitation), atmospheric CO2, and land use change. Rates of annual DIC export are projected to increase by 65% under the high emission scenario (A2) and 35% under the low emission scenario (B1) between the 2000s and the 2090s. Climate‐related changes along with rising atmospheric CO2 together would account for over 90% of the total increase in DIC export throughout the 21st century. The predicted increase in DIC export from the Mississippi River basin would alter chemistry of the coastal ocean unless appropriate climate mitigation actions are taken in the near future.
Bio-methane generation from organic waste : a review

Anaerobic digestion of organic waste can address both energy recovery and pollution control. A variety of agricultural, industrial and domestic wastes can be anaerobically digested as they contain easily biodegradable material. Biogas contains 50 -70% methane and 30-50% carbon dioxide as well as small a amounts of other gases with calorific value of about 21-24 MJ/m 3 . This paper reviews the history of biogas, biogas production stages and operating parameters. The anaerobic digestion configuration and potential substrates for biogas production are also considered.
Application of Åström's method to supply chain inventory problems: A reverse logistics scenario

Abstract: A simple dynamic model of a hybrid manufacturing / remanufacturing system is investigated. In particular we study an infinite horizon, continuous time, APIOBPCS (Automatic Pipeline Inventory and Order Based Production Control System) model. We specifically highlight the effect of remanufacturing lead-time and the return rate on the inventory variance and bullwhip produced by the ordering policy. Our results clearly show that a larger return rate leads to less bullwhip and less inventory variance, thus returns can be used to absorb demand fluctuations to some extent. Longer remanufacturing lead-times have less impact at reducing inventory variance and bullwhip than shorter lead-times. We conclude, within our specified system, that inventory variance and bullwhip is always less in supply chain with returns than without returns.
Near-Inertial Wave Propagation in the Western Arctic

Abstract From October 1997 through October 1998, the Surface Heat Budget of the Arctic (SHEBA) ice camp drifted across the western Arctic Ocean, from the central Canada Basin over the Northwind Ridge and across the Chukchi Cap. During much of this period, the velocity and shear fields in the upper ocean were monitored by Doppler sonar. Near-inertial internal waves are found to be the dominant contributors to the superinertial motion field. Typical rms velocities are 1–2 cm s−1. In this work, the velocity and shear variances associated with upward- and downward-propagating wave groups are quantified. Patterns are detected in these variances that correlate with underlying seafloor depth. These are explored with the objective of assessing the role that these extremely low-energy near-inertial waves play in the larger-scale evolution of the Canada Basin. The specific focus is the energy flux delivered to the slopes and shelves of the basin, available for driving mixing at the ocean boundaries. The energy and .
A mineral magnetic study of Holocene sedimentation in Lough Catherine, Northern Ireland

A suite of 6 m long Mackereth cores collected from Lough Catherine, Northern Ireland, form the basis of a study of sediment accumulation rates throughout the Holocene. A data set produced by measuring the magnetic susceptibility, artificially induced remanent magnetisations and density of the sediment was used to correlate the cores by means of a sequence slotting algorithm. The resulting sediment accumulation pattern was dated by reference to previous14C and palynological studies. The interpretation of the magnetic logs was complicated by the authigenic formation of the magnetic mineral greigite (Fe3S4) and by magnetite dissolution discovered during a period of low sediment accumulation between the end of the Lateglacial period (10,10014C years B.P.) and the elm decline (5,200 B.P.). More traditional methods of core analysis based on sediment density and also new palynological studies were used to correlate sections of the cores where the magnetic results were least amenable to core matching on account of low downcore variability and low accumulation rate. The accumulation rate, a direct indication of catchment denudation, has accelerated fivefold during the Holocene. The sediment accumulation rate has increased most dramatically since the elm decline at 5,200 B.P., reflecting the increasing degree of human disturbance.
PLANNED GENTRIFICATION AND NEIGHBORHOOD DYNAMICS IN HARRISBURG, PENNSYLVANIA

In response to calls by Lees (2000) and others to address "new wrinkles" in the "geography of gentrification," several recent studies have focused on the influence of urban policy on gentrification. Here we present a case study in Harrisburg, PA that investigates neighborhood dynamics and the influence of planned gentrification efforts in two neighborhoods, South Allison Hill and Capitol Heights, using a stable neighborhood, Midtown, as a baseline. This comparison is especially salient to research in the geography of gentrification because each neighborhood represents two different strategies of planned gentrification. In the case of Capitol Heights, the City of Harrisburg and its private partners have performed broad scale block-level teardowns and rebuilds. In contrast, urban renewal projects in South Allison Hill have focused on parcel scale rehabilitation projects, usually in partnership with individual homeowners or businesses, with the intention of creating small footholds of urban renewal throughout the neighborhood. Our comparison focuses on the progress of gentrification in these two neighborhoods as measured by parcel-level variables, including vacancy of parcels within neighborhoods, frequency of parcels that are changing, and spatial estimates of land and building values. Our findings related to the progress of gentrification in these neighborhoods were then validated in the field. In Capitol Heights, urban revitalization is predictably dramatic while the success of planned gentrification efforts in South Allison Hill is less certain. However, these results are the first in a longitudinal study of neighborhood dynamics in Harrisburg, PA and thus provide an important foundation for future studies.
Dynamic Page Placement to Improve Locality in CC-NUMA Multiprocessors for TPC-C

The use of CC-NUMA multiprocessors complicates the placement of physical memory pages. Memory closest to a processor provides the best access time, but optimal memory page placement is a difficult problem with process movement, multiple processes requiring access to the same physical memory page, and application behavior changing over execution time. We use dynamic page placement to move memory pages where needed for the database benchmark TPC-C executing on a four node CC-NUMA multiprocessor. Dynamic page placement achieves local memory accesses up to 73% of the time instead of the static page placement results of 34% locality achieved with first touch and 25% with round robin. This can result in a 17% improvement in performance.
CHANGES IN FATTY ACID COMPOSITION OF HUMAN BRAIN MYELIN LIPIDS DURING MATURATION 1

Abstract— The variation with age of the fatty acid composition of the major lipids in human brain myelin was compared with that of cerebral white matter from the same region. The myelin was isolated from the semiovale centre of the cerebrum of 27 subjects neonatal to old aged. The phospholipid, cholesterol and galactolipid concentrations were determined in all the samples, as were the proportions of the major phospholipid classes. The proportions of cholesterol and especially of the galactolipids increased in myelin during the first 6 months, and in cerebral white matter up to 2 years. During this period the individual phospholipids also varied substantially. Serine phosphoglycerides and especially sphingomyelins increased, and choline phosphoglycerides decreased.
Combined Field Integral Equation-Based Theory of Characteristic Mode

Conventional electric field integral equation-based theory is susceptible to the spurious internal resonance problem when the characteristic modes (CMs) of closed perfectly conducting objects are computed iteratively. In this paper, we present a combined field integral equation-based theory to remove the difficulty of internal resonances in CMs analysis. The electric and magnetic field integral operators are shown to share a common set of nontrivial characteristic pairs (values and modes), leading to a generalized eigenvalue problem which is immune to the internal resonance corruption. Numerical results are presented to validate the proposed formulation. This work may offer efficient solutions to CM analysis which involves electrically large closed surfaces.