Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of drip irrigation regimes and fertigation levels on yield of maize (Zea mays L.).

Field experiments were conducted at Tamil Nadu Agricultural University, during Kharif 2008 and Kharif 2009 at Coimbatore to study the effect of drip irrigation regimes and fertigation levels on yield of maize. The experiment was laid out in split plot design with three replications. The treatments included two irrigation regimes in main plot and eight fertigation levels in sub plot. In main plot, two irrigation regimes viz., M1 Irrigation through drip at 75 per cent PE once in 3 days, M2 Irrigation through drip at 100 per cent PE once in 3 days were accommodated. The sub plot treatments consisted of eight fertigation levels viz., S1 Drip fertigation with 75 per cent RDF (P as basal), S2 Drip fertigation with 100 per cent RDF (P as basal), S3 Drip fertigation with 125 per cent RDF (P as basal), S4 Drip fertigation with 150 per cent RDF (P as basal), S5 Drip fertigation with 75 per cent RDF with P through WSF (17:44:0), S6 Drip fertigation with 100 per cent RDF with P through WSF (17:44:0), S7 Drip fertigation with 125 per cent RDF with P through WSF (17:44:0) and S8 Drip fertigation with 150 per cent RDF with P through WSF (17:44:0). Control plots with surface irrigation at 0.80 IW / CPE ratio for maize with soil application of 100 per cent RDF were maintained separately for comparison. Drip irrigation at 100 % PE once in 3 days resulted in significantly higher grain yield of maize followed by irrigation at 75 % PE. Drip fertigation at 150 per cent RDF (225: 112.5: 112.5) with P through water soluble fertilizer registered significantly higher grain yield. Considering the high cost of water soluble fertilizers, drip irrigation at 100 per cent PE with fertigation level of 125 per cent RDF with P as basal could be an alternative option to realize a reasonably good yields in maize.
Climate control on alluvial sediment storage in the northern foreland of the Tatra Mountains since the late Pleistocene

Abstract Numerical dating and geomorphic studies on alluvial sediment were undertaken in the uppermost reaches of the Dunajec River catchment in the northern foreland of the Tatra Mountains of Poland. Successions of alluvial deposits in river terraces and alluvial fans are common in this region. In particular, alluvial fans deposited a thick succession of sediment in the intramontane Orawa–Nowy Targ Depression, and terraces are preserved as two cut-and-fill and six strath terraces along the uplifting sections of river courses. We identify several alluviation phases within the alluvial successions that occurred since Marine Oxygen Isotope Stage 6. These sediments show that deposition largely occurred under temperate-climate conditions. This is in spite of a potential strong impact from headwater glaciers under cold-climate conditions. Glacially produced sediments were largely stored within frontal moraines and proglacial floodplains. These glaciogenic sediments were eroded and resedimented during glacier retreat. We therefore conclude that “warm” alluviation is the dominant process forming alluvial successions in this region.
VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease

CBL and CBL-B ubiquitin ligases play key roles in hematopoietic stem cell homeostasis and their aberrations are linked to leukemogenesis. Mutations of CBL, often genetically-inherited, are particularly common in Juvenile Myelomonocytic Leukemia (JMML), a disease that manifests early in children. JMML is fatal unless corrected by bone marrow transplant, which is effective in only half of the recipients, stressing the need for animal models that recapitulate the key clinical features of this disease. However, mouse models established so far only develop hematological malignancy in adult animals. Here, using VAV1-Cre-induced conditional CBL/CBL-B double knockout (DKO) in mice, we established an animal model that exhibits a neonatal myeloproliferative disease (MPD). VAV1-Cre induced DKO mice developed a strong hematological phenotype at postnatal day 10, including severe leukocytosis and hepatomegaly, bone marrow cell hypersensitivity to cytokines including GM-CSF, and rapidly-progressive disease and invariable lethality. Interestingly, leukemic stem cells were most highly enriched in neonatal liver rather than bone marrow, which, along with the spleen and thymus, were hypo-cellular. Nonetheless, transplantation assays showed that both DKO bone marrow and liver cells can initiate leukemic disease in the recipient mice with seeding of both spleen and bone marrow. Together, our results support the usefulness of the new hematopoietic-specific CBL/CBL-B double KO animal model to study JMML-related pathogenesis and to further understand the function of CBL family proteins in regulating fetal and neonatal hematopoiesis. To our knowledge, this is the first mouse model that exhibits neonatal MPD in infancy, by day 10 of postnatal life.
Where are the politics in responsible innovation? European governance, technology assessments, and beyond

Responsible innovation (RI) is founded on the idea that present modes of innovating with science and technology fail because they insufficiently take into account societal needs and values. Hence, proponents of RI solicit society's opinions in an attempt to render science and technology developments, institutions, and policies more socially responsive. This article asks how the RI concept is taken up and elaborated, based on accounts developed on the European Union policy level and on a Flemish, technology assessment level. It finds that, notwithstanding important differences between these two deliberative frameworks, neither one leaves much room for politics, understood as the constitution and contestation of power. Rather, these frameworks largely ignore questions about the politics in and of deliberation, the authoritative allocation of values, and the institutional uptake of deliberative engagements. The article's aim is to provide constructive criticism of the RI paradigm by rendering these political.
Classifying Dementia Using Local Binary Patterns from Different Regions in Magnetic Resonance Images

Dementia is an evolving challenge in society, and no disease-modifying treatment exists. Diagnosis can be demanding and MR imaging may aid as a noninvasive method to increase prediction accuracy. We explored the use of 2D local binary pattern (LBP) extracted from FLAIR and T1 MR images of the brain combined with a Random Forest classifier in an attempt to discern patients with Alzheimer's disease (AD), Lewy body dementia (LBD), and normal controls (NC). Analysis was conducted in areas with white matter lesions (WML) and all of white matter (WM). Results from 10-fold nested cross validation are reported as mean accuracy, precision, and recall with standard deviation in brackets. The best result we achieved was in the two-class problem NC versus AD + LBD with total accuracy of 0.98 (0.04). In the three-class problem AD versus LBD versus NC and the two-class problem AD versus LBD, we achieved 0.87 (0.08) and 0.74 (0.16), respectively. The performance using 3DT1 images was notably better than when using FLAIR images. The results from the WM region gave similar results as in the WML region. Our study demonstrates that LBP texture analysis in brain MR images can be successfully used for computer based dementia diagnosis.
Lignin Composition and Structure Differs between Xylem, Phloem and Phellem in Quercus suber L.

The composition and structure of lignin in different tissues—phellem (cork), phloem and xylem (wood)—of Quercus suber was studied. Whole cell walls and their respective isolated milled lignins were analyzed by pyrolysis coupled with gas chromatography/mass spectrometry (Py-GC/MS), two-dimensional nuclear magnetic resonance spectroscopy (2D-NMR) and derivatization followed by reductive cleavage (DFRC). Different tissues presented varied p-hydroxyphenyl:guaiacyl:syringyl (H:G:S) lignin compositions. Whereas lignin from cork has a G-rich lignin (H:G:S molar ratio 2:85:13), lignin from phloem presents more S-units (H:G:S molar ratio of 1:58:41) and lignin from xylem is slightly enriched in S-lignin (H:G:S molar ratio 1:45:55). These differences were reflected in the relative abundances of the different interunit linkages. Alkyl-aryl ethers (β–O–4′) were predominant, increasing from 68% in cork, to 71% in phloem and 77% in xylem, as consequence of the enrichment in S-lignin units. Cork lignin was enriched in condensed structures such as phenylcoumarans (β-5′, 20%), dibenzodioxocins (5–5′, 5%), as corresponds to a lignin enriched in G-units. In comparison, lignin from phloem and xylem presented lower levels of condensed linkages. The lignin from cork was highly acetylated at the γ-OH of the side-chain (48% lignin acetylation), predominantly over G-units; while the lignins from phloem and xylem were barely acetylated and this occurred mainly over S-units. These results are a first time overview of the lignin structure in xylem, phloem (generated by cambium), and in cork (generated by phellogen), in agreement with literature that reports that lignin biosynthesis is flexible and cell specific.
Accurate modeling of optical multiplexer/demultiplexer concatenation in transparent multiwavelength optical networks

This paper presents an accurate theoretical model for the study of concatenation of optical multiplexers/demultiplexers (MUXs/DMUXs) in transparent multiwavelength optical networks. The model is based on a semianalytical technique for the evaluation of the error probability of the network topology. The error-probability evaluation takes into account arbitrary pulse shapes, arbitrary optical MUX/DMUX, and electronic low-pass filter transfer functions, and non-Gaussian photocurrent statistics at the output of the direct-detection receiver. To illustrate the model, the cascadability of arrayed waveguide grating (AWG) routers in a transparent network element chain is studied. The performance of the actual network is compared to the performance of a reference network with ideal optical MUXs/DMUXs. The optical power penalty at an error probability of 10/sup -9/ is calculated as a function of the number of cascaded AWG routers, the bandwidth of AWG routers, and the laser carrier frequency offset from the channel's nominal frequency.
Finite group with c-normal or s-quasinormally embedded subgroups

If P is a p-group for some prime p we shall write M (P ) to denote the set of all maximal subgroups of P and Md(P ) = {P1, . , Pd} to denote any set of maximal subgroups of P such that ∩d i=1 Pi = Φ(P ) and d is as small as possible. In this paper, the structure of a finite group G under some assumptions on the c-normal or s-quasinormally embedded subgroups in Md(P ), for each prime p, and Sylow p-subgroups P of G is researched. Some known results are generalized. Key–Words: c-normal subgroup; s-quasinormally embedded subgroup; supersolvable groups; Sylow p-subgroup; Finite groups.
NAIRAS aircraft radiation model development, dose climatology, and initial validation

The Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS) is a real‐time, global, physics‐based model used to assess radiation exposure to commercial aircrews and passengers. The model is a free‐running physics‐based model in the sense that there are no adjustment factors applied to nudge the model into agreement with measurements. The model predicts dosimetric quantities in the atmosphere from both galactic cosmic rays (GCR) and solar energetic particles, including the response of the geomagnetic field to interplanetary dynamical processes and its subsequent influence on atmospheric dose. The focus of this paper is on atmospheric GCR exposure during geomagnetically quiet conditions, with three main objectives. First, provide detailed descriptions of the NAIRAS GCR transport and dosimetry methodologies. Second, present a climatology of effective dose and ambient dose equivalent rates at typical commercial airline altitudes representative of solar cycle maximum and solar cycle minimum conditions and spanning the full range of geomagnetic cutoff rigidities. Third, conduct an initial validation of the NAIRAS model by comparing predictions of ambient dose equivalent rates with tabulated reference measurement data and recent aircraft radiation measurements taken in 2008 during the minimum between solar cycle 23 and solar cycle 24. By applying the criterion of the International Commission on Radiation Units and Measurements (ICRU) on acceptable levels of aircraft radiation dose uncertainty for ambient dose equivalent greater than or equal to an annual dose of 1 mSv, the NAIRAS model is within 25% of the measured data, which fall within the ICRU acceptable uncertainty limit of 30%. The NAIRAS model predictions of ambient dose equivalent rate are generally within 50% of the measured data for any single‐point comparison. The largest differences occur at low latitudes and high cutoffs, where the radiation dose level is low. Nevertheless, analysis suggests that these single‐point differences will be within 30% when a new deterministic pion‐initiated electromagnetic cascade code is integrated into NAIRAS, an effort which is currently underway.
Cardiovascular Consequences of Obesity and Type 2 Diabetes Angiotensin-( 1 – 7 ) treatment mitigates right ventricular fibrosis as a distinctive feature of diabetic cardiomyopathy

Hao PP, Yang JM, Zhang MX, Zhang K, Chen YG, Zhang C, Zhang Y. Angiotensin-(1–7) treatment mitigates right ventricular fibrosis as a distinctive feature of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 308: H1007–H1019, 2015. First published February 27, 2015; doi:10.1152/ajpheart.00563. 2014. —In diabetic patients, left ventricular (LV) remodeling is highly prevalent; however, little is known about the impact of diabetes on right ventricular (RV) structure and function. We recently found that overexpression of angiotensin (ANG)-converting enzyme 2 (ACE2), which metabolizes ANG-II to ANG-(1–7) and ANG-I to ANG-(1–9), may improve LV remodeling in diabetic cardiomyopathy (DCM). Here, we aimed to assess whether LV remodeling and dysfunction are paralleled by RV alterations and the effects of ANG-(1–7) on RV remodeling in DCM. After 12 wk of diabetes induced by a single intraperitoneal injection of streptozotocin, rats were treated with saline, ANG-(1–7), perindopril, ANG-(1–7) plus perindopril, ANG-(1–7) plus Mas receptor antagonist A779, or ANG-(1–7) plus ANG-II type 2 receptor antagonist PD123319 for 4 wk. RV remodeling in diabetic rats was indicated by fibrosis of the RV free wall in the absence of hypertrophy and apoptosis. Treatment with ANG-(1–7) prevented diabetes-induced RV fibrosis and dysfunction. ANG-(1–7) (800 ng·kg ·min ) was superior to perindopril in improving RV fibrosis. The major mechanisms involved a complex interaction of ANG-II type 2 and Mas receptors for subsequent downregulation of ACE expression and activity and ANG-II type 1 receptor expression, as well as upregulation of ACE2 expression and activity and the expression of ANG-II type 2 receptor and sarco(endo)plasmic reticulum Ca -ATPase. Thus RV fibrosis and dysfunction plays a central role in DCM, and ANG-(1–7) mitigates diabetes-induced RV alterations.
From Autonomy to Accountability: the role of clinical practice guidelines in professional power

Evidence-based medicine (EBM) aims to address the persistent problem of clinical practice variation with the help of various tools, including standardized practice guidelines. Based on a systematic evaluation of the available scientific evidence, these guidelines offer recommendations for clinicians about details of patient care and clinical decision making. Because clinical practice guidelines specify how health care should be performed, they could be considered a threat to clinical and professional autonomy. Inspired by the theory of countervailing powers, this article explores how clinical practice guidelines have shifted the focus of professional power from autonomy to accountability. Professional organizations develop clinical practice guidelines as a service to their members but do not require strict adherence to the guidelines. Indeed, implementation studies show at best a modest change in clinical behavior. Such non-adherence might render a profession vulnerable, however, when third parties seize upon guidelines and offer financial incentives to keep clinicians accountable for delivering optimal patient care. [End Page 490]
Rank − 1 / 2: A Simple Way to Improve the OLS Estimation of Tail Exponents

Despite the availability of more sophisticated methods, a popular way to estimate a Pareto exponent is still to run an OLS regression: log(Rank) = a − b log(Size), and take b as an estimate of the Pareto exponent. The reason for this popularity is arguably the simplicity and robustness of this method. Unfortunately, this procedure is strongly biased in small samples. We provide a simple practical remedy for this bias, and propose that, if one wants to use an OLS regression, one should use the Rank −1 / 2, and run log(Rank − 1 / 2) = a − b log(Size). The shift of 1 / 2 is optimal, and reduces the bias to a leading order. The standard error on the Pareto exponent ζ is not the OLS standard error, but is asymptotically (2 / n)1 / 2ζ. Numerical results demonstrate the advantage of the proposed approach over the standard OLS estimation procedures and indicate that it performs well under dependent heavy-tailed processes exhibiting deviations from power laws. The estimation procedures considered are illustrated using an empirical application to Zipf’s law for the United States city size distribution.
Channel and Multiuser Diversities in Wireless Systems: Delay-Energy Tradeoff

We consider a communication system with multi-access fading channel. Each user in the system requires certain rate guarantee. Our main contribution is to devise a scheduling scheme called "Opportunistic Super-position Coding"that satisfies the users' rate requirements. Using mean-field analysis, i.e., when the number of users go to infinity, we analytically show that the energy required to guarantee the required user rate can be made as small as required at the cost of a higher delay ("delay- energy tradeoff"). We explicitly compute the delay under the proposed scheduling policy and discuss how delay differentiation can be achieved. We extend the results to multi-band multi-access channel. Finally, all the results can be generalized in a straightforward fashion to broadcast channel because of the uplink-downlink duality.
Identifying depressed patients with and without suicidal ideation by finger photo-plethysmography

Major Depressive Disorder (MDD) is a serious mental disorder that if untreated not only affects physical health but also has a high risk of suicide. While the neurophysiological phenomena that contribute to the formation of Suicidal Ideation (SI) are still ill-defined, clear links between MDD and cardiovascular disease have been reported. The aim of this study is to extract suitable features from arterial pulse signals with a view to predicting SI within MDD and control groups. Sixteen unmedicated MDD patients with a history of SI (MDDSI+), sixteen without SI (MDDSI-) and twenty-nine healthy subjects (CONT) were recruited at a psychiatric clinic in the UAE. Depression severity and SI were assessed using the Hamilton Depression Rating Scale and Beck Depression Inventory. Pulse Wave Amplitude (PWA) was calculated as the difference between the peak (Systole) and the valley (Diastole) of the arterial pulse within each cardiac cycle. Then, 2D Tone-Entropy (TE) features were extracted from the Systole, Diastole and PWA time series. The TE features extracted from Diastole were the best markers for predicting MDDSI+. The overall classification accuracies of Classification and Regression Tree (CART) model by using TE features of Systole, Diastole and PWA were 88.52%, 90.2% and 88.52% respectively. When all TE features were combined, accuracy increased up to 93.44% in identifying MDDSI+/MDDSI-/Control groups.
Variable-Rate Application for Phosphorus and Potassium: Impacts on Yield and Nutrient Management

Soil fertility management can be improved by use of precision agriculture technologies. Global positioning systems (GPS), yield monitors, various forms of remote sensing, geographical information system (GIS) software, and variable-rate technology (VRT) are available for use by producers. Dense soil sampling, crop scouting, and other practices complete the new technological package. Soil testing is a diagnostic tool especially adapted for site-specific management. At the same time, GPS and GIS can greatly improve soil testing when these technologies are used to better describe nutrient levels across a field. The spatial variation of plant nutrients over a field makes soil sampling the most important and common source of error in soil testing. Therefore, Georeferenced soil sampling, soil test mapping, and fertilizer application with VRT can improve the efficacy of fertilization compared with the conventional practice of collecting a composite soil sample from large areas and applying a single fertilizer rate over a field.
Clinicopathological and prognostic significance of Ki-67 immunohistochemical expression in gastric cancer: a systematic review and meta-analysis

The prognostic significance of Ki-67 in patients with gastric cancer (GC) remains controversial. The aim of our meta-analysis is to evaluate its association with clinicopathological characteristics and prognostic value in patients with GC. PubMed, EMBASE, and Web of Science were systematically searched up to May 2017. Twenty-two studies including 3,825 patients with GC were analyzed. The meta-analysis indicated that the incidence difference of Ki-67 expression in GC patients was significant when comparing the older group to younger group (odds ratio [OR] =1.44, 95% confidence interval [CI] 1.19, 1.75), lymph node positive group to negative group (OR =1.49, 95% CI 1.20, 1.84), the large size tumor group to the small size tumor group (OR =1.27, 95% CI 1.24, 1.68) and the TNM stage III+IV group to TNM stage I+II group (OR =2.28, 95% CI 1.66, 3.12). However, no statistical differences existed in gender. The detection of Ki-67 significantly correlated with the overall survival of patients (hazard ratio =1.51, 95% CI 1.31, 1.72). Our study suggested that Ki-67 overexpression was associated with poor prognosis in GC patients. Ki-67 positive rates may be associated with age, lymph node metastasis, tumor size, and TNM staging system in GC patients.