Miracle-dz/UniFAR-FTUs huggingface dataset:
Developmental Change in a Spatial Task of Attentional Capacity: An Essay Toward an Integration of Two Working Memory Models

The objective of this paper is to illustrate the complementarity of two lines of studies on Working Memory, the neo-Piagetian models of Pascual-Leone and Case on the one hand, and Baddeley's model, on the other. After a brief summary of each model, their similarities and differences are reviewed. An empirical longitudinal study is then presented as an illustration. Four cohorts of children, aged 5, 6, 8, and 10 years on the first assessment, were examined once a year over five years, with a short-term memory task (Mr Peanut), asking for the recall of the location of coloured spots in a clown figure. Two versions were used: a unicoloured task (Peanut-P) and a multicoloured task (Peanut-C), in which subjects had to recall both positions and colours. Three aspects of the results are emphasised. First, it was found that performances in Peanut-C increased with item complexity up to a certain level, beyond which they tended to remain stable; this stability was interpreted as reflecting the limits in processing resources which are postulated by neo-Piagetian models. Secondly, a drastic diminution in the performances was observed on the fourth year, corresponding to a change in the way of responding: The task was computerised, and subjects had to answer, using a computer mouse. It is argued that the monitoring of the mouse disrupts performances because it draws on the same limited resources as the memory task. Finally, results showed that the monitoring of the mouse interferes more with the recall of positions than with the recall of colours, as could be expected if monitoring a computer mouse represents a spatial interference task. Methodological drawbacks of the studies are also discussed, and suggestions for further research indicated.
Organizational commitment: The utility of an integrative definition.

The authors report a series of 9 studies (N = 2,734) in which they evaluated the construct definition, measurement, and validation of organizational commitment (OC). An integrated examination of a wide range of antecedents of the various dimensions of OC was conducted. Results support the existence of 3 major OC dimensions (affective, continuance, and normative), with 2 subdimensions (personal sacrifice and lack of alternatives) for the continuance dimension. Results suggest that the widely used Organizational Commitment Questionnaire assesses primarily the affective dimension. Results provide various levels of support for the set of proposed antecedents. Implications for construct definition, measurement, and future research are discussed
Furnished Imagination: The Impact of Preservice Teacher Training on Early Career Work in TESOL

This article presents the findings of an impact study of a short teacher training course in teaching English to speakers of other languages (TESOL). Impact is conceptualised as teacher learning, particularly perceived achievements in learning, evidenced in the ways teachers talk about their work in TESOL. The theoretical framework for the research draws on sociocultural theories of learning, particularly situated learning theory and identity formation within communities of practice. In making these links and relating them to a specific programme for teachers in TESOL, this article furthers understanding of how teachers learn in a preservice course in ways which translate to readiness for work. The analysis of interview data from 27 novice teachers in their first months at work reflects a positive and intense learning experience on the course, which establishes both confidence and a clear idea of what the TESOL task involves. The authors relate these findings in the data to the construct of furnished imagination: the combination of knowledge, procedural awareness and skills, dispositions, and identity which the teachers take from the course as the conceptual toolkit for work in TESOL. The imagination is furnished through the intense, iterated cycles of input, observation, performance, and feedback as well as through interactions with admired teacher educators.
PROTEIN FUNCTION PREDICTION WITH AMINO ACID SEQUENCE AND SECONDARY STRUCTURE ALIGNMENT SCORES

In this study, we use amino acid sequence and actual or predicted secondary structure for protein function prediction. We investigate both sequence-sequence and Hidden Markov Model (HMM) profile-profile similarity measures that use both sequence and secondary structure information. Our findings on a data set consisting of 5 Gene Ontology (GO) Molecular functions and 785 sequences show that actual secondary structure can help for protein function prediction when it is used with sequence-sequence alignment scores. We did not find a consistent improvement in function prediction when predicted or actual secondary structure is used with profile-profile alignment scores.
Associations between Dating Violence and High-Risk Sexual Behaviors among Male and Female Older Adolescents

This study sought to evaluate associations between adolescent dating violence victimization (DV) and high-risk sexual behaviors. Males (n = 71) and females (n = 189) reporting DV were compared to 671 males and 720 females (overall mean age 20.4 years) reporting no DV on high-risk sexual behaviors (casual sexual partner, multiple sexual partners no contraceptive use unprotected intercourse). DV was reported by 9.6% males and 20.8% females. All males reporting both physical and sexual DV acknowledged high-risk sexual behavior. Furthermore, most female peers (75.2%) reporting physical and sexual DV acknowledged high-risk sexual behavior. Health programs and care professionals should target violence prevention and contraception education, and promote early intervention to reduce high-risk sexual behaviors, particularly among those reporting dating violence.
Acute Effects of Cocaine on Movement-Related Firing of Dorsolateral Striatal Neurons Depend on Predrug Firing Rate and Dose

To investigate striatal mechanisms underlying the acute effects of stimulants on motor behavior, firing rates (FRs) of striatal neurons related specifically to vertical head movement were studied exclusively during vertical head movements. Precocaine FRs were recorded after intraperitoneal saline injection (time 1; T1), and rats performed conditioned vertical head movements (>10,000) similar to those induced by stimulants. After cocaine injection (0, 5, 10, or 20 mg/kg; T2), animals continued in the task. The proportion of long head movements was increased by low doses but decreased by the high dose, which induced stereotypic head movements. Comparing each neuron's FR during movements that were matched between T1 and T2 (e.g., regarding direction, distance), cocaine's effects depended on predrug FR and dose. Plots regressing T2FR on T1FR showed dose-dependent, “clockwise” rotations of regression lines in plots of all the neurons' average FRs and of individual neurons' FRs during different movements. All three doses elevated normally low FRs; the high dose also suppressed many higher FRs. Enhancement of a neuron's FR associated with weak and suppression of FR associated with strong corticostriatal inputs contradict several current theories of dopamine (DA) function. Induction of stereotypy by a single, high-dose injection suggests that this cocaine level exceeded that in other studies using cocaine self-administration, in which stereotypy develops only after several sessions. Suppressive effects observed only at the high dose and in numerous electrophysiological studies of DA agonist effects may be unrepresentative of uniform elevations in lateral striatal firing related to movement observed at lower cocaine levels.
Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor

The phytoestrogen resveratrol has been reported to possess cancer chemo-preventive activity on the basis of its effects on tumor cell lines and xenograft or carcinogen-inducible in vivo models. Here we investigated the effects of resveratrol on spontaneous mammary carcinogenesis using Δ16HER2 mice as HER2+/ERα+ breast cancer model. Instead of inhibiting tumor growth, resveratrol treatment (0.0001% in drinking water; daily intake of 4μg/mouse) shortened tumor latency and enhanced tumor multiplicity in Δ16HER2 mice. This in vivo tumor-promoting effect of resveratrol was associated with up-regulation of Δ16HER2 and down-regulation of ERα protein levels and was recapitulated in vitro by murine (CAM6) and human (BT474) tumor cell lines. Our results demonstrate that resveratrol, acting as a proteasome inhibitor, leads to Δ16HER2 accumulation which favors the formation of Δ16HER2/HER3 heterodimers. The consequential activation of downstream mTORC1/p70S6K/4EBP1 pathway triggers cancer growth and proliferation. This study provides evidence that resveratrol mechanism of action (and hence its effects) depends on the intrinsic molecular properties of the cancer model under investigation, exerting a tumor-promoting effect in luminal B breast cancer subtype models.
Immunoblot detection of oligoclonal anti‐myelin basic protein IgG antibodies in cerebrospinal fluid in multiple sclerosis

Migration properties and occurrence of antibodies against myelin basic protein (MBP) in paired CSF and serum specimens from patients with multiple sclerosis (MS) were demonstrated after agarose isoelectric focusing, immunoblot transfer, and immunoperoxidase staining. Oligoclonal IgG antibody bands directed against MBP were found in the CSF of 9 of 28 patients with MS (32%), but not in the CSF of any of 34 patients with other neurologic diseases. No serum showed anti-MBP antibody bands. The CSF anti-MBP antibodies migrated to the anodal region of the IgG area in a different fashion from oligoclonal IgG and anti-measles IgG antibodies, which were detected in parallel. The anti-MBP bands were transient in three of seven patients whom we studied consecutively. Enzyme-linked immunosorbent assay (ELISA) of serum and CSF for detection of IgG reactivity against MBP showed absorbance values above 2 standard deviations of controls in 44% of the MS patients and in 21% of those with other neurologic diseases. Results of this assay correlated partly with those of the immunoblot assay. ELISA positive and immunoblot negative results might be due to a broad polyclonal anti-MBP antibody response.
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide.

BACKGROUND Hydrogen sulfide (H(2)S) is considered as the third gasotransmitter after nitric oxide and carbon monoxide. This gas molecule participates in the regulation of renal function. Diabetic nephropathy (DN) is one of the major chronic complications of diabetes. The present study aimed to explore the changes in H(2)S metabolism in the early stage of DN and the effects of H(2)S on cultured rat renal glomerular mesangial cells (MCs). METHODS Cultured rat MCs and streptozotocin (STZ)-induced diabetic rats were used in this study. Expression levels of cystathionine γ-lyase (CSE), transforming growth factor-β1 (TGF-β1) and collagen IV in rat renal cortex and in cultured MCs were determined by quantitative real-time PCR and western blot. Reactive oxygen species (ROS) released from rat MCs was assessed by fluorescent probe assays. MCs proliferation was analyzed by 5'-bromo-2'-deoxyuridine incorporation assay. RESULTS H(2)S levels in the plasma and renal cortex and the levels of CSE messenger RNA (mRNA) and protein in renal cortex were significantly reduced, while the levels of TGF-β1 and collagen IV increased 3 weeks after STZ injection. Administration of NaHS, a H(2)S donor, reversed the increases in TGF-β1 and collagen IV in diabetic rats. By contrast, NaHS did not alter the TGF-β1 and collagen IV levels in non-diabetic rats. But NaHS lowered the CSE mRNA level in renal cortex. Exposure to high glucose promoted ROS generation and cell proliferation, up-regulated the expression of TGF-β1 and collagen IV but decreased the CSE expression in cultured MCs. Treatment of cultured MCs with NaHS reversed the effect of high glucose. NaHS did not change ROS generation, cell proliferation, TGF-β1 and collagen IV expression in the cells cultured with normal glucose. Reduction of endogenous H(2)S generation by DL-propargylglycine, a CSE inhibitor, produced similar cellular effects as high glucose, including increases in cell proliferation, TGF-β1 and collagen IV expressions and ROS generation. CONCLUSION Suppressed CSE-catalyzed endogenous H(2)S production in the kidney by hyperglycemia may play an important role in the pathogenesis of DN.
The influence of visual short-term memory on size perception

We show that perceived size of visual stimuli can be altered by matches between the contents of visual short-term memory and stimuli in the scene. Observers were presented with a colour cue (to hold in working memory or to merely identify) and subsequently had to indicate which of the two different-coloured objects presented simultaneously on the screen appeared bigger (or smaller). One of the two objects for size judgements had the same colour as the cue (matching stimulus) and the other did not (mismatching stimulus). Perceived object size was decreased by the reappearance of the recently seen cue, as there were more size judgement errors on trials where the matching stimulus was physically bigger (relative to the mismatching stimulus) than on trials where the matching stimulus was physically smaller. The effect occurred regardless of whether the visual cue was actively maintained in working memory or was merely identified. The effect was unlikely generated by the allocation of attention, because shifting attention to a visual stimulus actually increased its perceived size. The findings suggest that visual short-term memory, whether explicit or implicit, can decrease the perceived size of subsequent visual stimuli.
Structural resonance and mode of flutter of hummingbird tail feathers

SUMMARY Feathers can produce sound by fluttering in airflow. This flutter is hypothesized to be aeroelastic, arising from the coupling of aerodynamic forces to one or more of the feather's intrinsic structural resonance frequencies. We investigated how mode of flutter varied among a sample of hummingbird tail feathers tested in a wind tunnel. Feather vibration was measured directly at ~100 points across the surface of the feather with a scanning laser Doppler vibrometer (SLDV), as a function of airspeed, Uair. Most feathers exhibited multiple discrete modes of flutter, which we classified into types including tip, trailing vane and torsional modes. Vibratory behavior within a given mode was usually stable, but changes in independent variables such as airspeed or orientation sometimes caused feathers to abruptly ‘jump’ from one mode to another. We measured structural resonance frequencies and mode shapes directly by measuring the free response of 64 feathers stimulated with a shaker and recorded with the SLDV. As predicted by the aeroelastic flutter hypothesis, the mode shape (spatial distribution) of flutter corresponded to a bending or torsional structural resonance frequency of the feather. However, the match between structural resonance mode and flutter mode was better for tip or torsional mode shapes, and poorer for trailing vane modes. Often, the 3rd bending structural harmonic matched the expressed mode of flutter, rather than the fundamental. We conclude that flutter occurs when airflow excites one or more structural resonance frequencies of a feather, most akin to a vibrating violin string.
Tradition meets pluralism: the receding Confucian values in the Taiwanese citizenship curriculum

Confucianism, long regarded as the key philosophy on personal character-building and interpersonal relations in Chinese society, used to be pivotal to citizenship education in Taiwan, but that has changed in the last 20 years. In the wake of democratization in the late 1980s, growing liberalism and pluralism in Taiwanese society prompted the authorities to widen the scope of the school curriculum to include a diversity of cultures and thus the influence of this ancient Chinese philosophy began to fade away. The new citizenship curriculum, introduced in 2010, is no longer structured around Confucian moral guidance, but has instead embraced pluralism. Confucianism, from the perspective of those Taiwanese citizenship curriculum designers who were interviewed, hinders the formation of civil society due to its overly strong emphasis on familial kinship and “sovereign-subject” paternalism. Engulfed by Confucian moral principles, the critical and reflective competence of the individual often fails to develop. The new citizenship programme therefore attempts to counter the emphasis on fostering “obedient citizens” under monolithic Confucian doctrines and envisions a resilient civil society open to pluralistic voices.
Research-led innovation in teaching and learning programming

We describe an attempt to bridge the gap between educational research and practical innovation by making a package of changes to an introductory programming module based on the insights of existing theoretical work. Theoretical principles are described, used to evaluate previous practices and then employed to guide systematic changes. Preliminary evaluation indicates substantial improvements in student performance and enjoyment while indicating areas in need of further work.
FEM and BEM Stress Analysis of Mandibular Bone Surrounding a Dental Implant

In the present work the structural behaviour of a mandible with a dental implant, considering a unilateral occlusion, is numerically analysed by means of the Finite Element Method (FEM) and the Boundary Element Method (BEM). The mandible, whose CAD model was obtained by computer tomography scans, is considered as completely edentulous and only modelled in the zone surrounding the implant. The material behaviour of bone is assumed as isotropic linear elastic or, alternatively, as orthotropic linear elastic. With reference to the degree of osteo-integration between the implant and the mandibular bone, a partial osteo-integration is considered; consequently a nonlinear contact analysis is performed, with allowance for friction at the interface between implant and bone. A model of a commercial dental implant is digitised by means of optical 3D scanning process and fully reconstructed in all its geometrical features. Special attention is drawn to the mathematical reconstruction of the CAD model in order to facilitate the meshing process in the BEM environment and reduce the geometrical imperfections generated during the CAD to CAE translation process. The results of FEM and BEM analyses in terms of stress distribution on the mandible are compared in order to benchmark the two methodologies against accuracy and pre-processing efforts.
Generalization of monod kinetics for analysis of growth data with substrate inhibition

The inhibitory effect of butanol on yeast growth has been studied for the strain Candida utilis ATCC 8205 growing aerobically on butanol under batch conditions. A mathematical expression was then proposed to fit the kinetic pattern of butanol inhibition on the specific growth rate: \documentclass{article}\pagestyle{empty}\begin{document}$$ \mu = \frac{{\mu _m S}}{{K_s + S}}\left[{1 - \frac{S}{{S_m }}} \right]^n $$\end{document}
On the Dynamics and Acoustics of Cloud Cavitation on an Oscillating Hydrofoil

Observations have been made of the growth and collapse of surface and cloud cavitation on a finite aspect ratio hydrofoil oscillating in pitch. The cavitation was recorded using both still and high-speed motion picture photography, and the variations with cavitation number and reduced frequency of oscillation were investigated. The noise generated by the cavity collapse was also measured and analyzed. The acoustic signals associated with individual cavity collapse events have been synchronized with the motion pictures, providing insights into the correspondence between the flow structures involved in the cavity collapse process and the sound generated by them.
The Relationship Among Malingering, Psychopathy, and the MMPI-2 Validity Scales in Maximum Security Forensic Psychiatric Inpatients

ABSTRACT The records of 392 men hospitalized in a maximum security forensic psychiatric hospital were reviewed. Demographic information was collected as well as data from the men's performance on the Psychopathy Checklist-Revised (PCL-R) and Minnesota Multiphasic Personality Inventory-2 (MMPI-2). Prevalence rates for malingering were low across the sample. However, results of chi-square analysis revealed that those who scored high on the PCL-R received a diagnosis of malingering significantly more frequently than those who scored low on the PCL-R. Clinical applications and theoretical implications of the results are discussed.
Mindfulness‐based stress reduction: A literature review and clinician's guide

PurposeTo provide nurse practitioners (NPs) with clinical research about Mindfulness-Based Stress Reduction (MBSR) and demonstrate its usefulness for reducing stress in a variety of populations. Data SourcesA literature review was conducted using the following databases: EBSCO, Cinahl, Pschyline, and Medline. English language articles published between 2000 and 2006 in peer-reviewed journals were reviewed. Search terms “mindfulness,”“meditation,” and “stress” were used. Additional information was obtained through select, reputable Internet sites. ConclusionsMBSR is an effective treatment for reducing stress and anxiety that accompanies daily life and chronic illness. MBSR is also therapeutic for healthcare providers, enhancing their interactions with patients. No negative side effects from MBSR have been documented. Implications for practiceMBSR is a safe, effective, integrative approach for reducing stress. Patients and healthcare providers experiencing stress or stress-related symptoms benefit from MBSR programs. NPs can safely and effectively use this intervention in a variety of patient populations.
Publication productivity among American criminologists: An analysis of gender, regional, and work differences

This study examines the research productivity of a random sample of members of the American Society of Criminology. A total of 178 respondents provided information on their publication productivity over the last five years. The results show that considerable variance exists within groups and among groups. Male Ph.D.s published more pages of books and journal articles than female Ph.D.s over the last five years, but the differences were not significant. Approximately 4 percent of male Ph.D.s failed to publish any journal articles, whereas almost 6 percent of female Ph.D.s had not published in journals. Nearly 40 percent of the Ph.D.s had failed to publish any material in books. Few significant differences were found among geographical regions, type of degree, and type of work.