Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards general models of player affect

While the primary focus of affective computing has been on constructing efficient and reliable models of affect, the vast majority of such models are limited to a specific task and domain. This paper, instead, investigates how computational models of affect can be general across dissimilar tasks; in particular, in modeling the experience of playing very different video games. We use three dissimilar games whose players annotated their arousal levels on video recordings of their own playthroughs. We construct models mapping ranks of arousal to skin conductance and gameplay logs via preference learning and we use a form of cross-game validation to test the generality of the obtained models on unseen games. Our initial results comparing between absolute and relative measures of the arousal annotation values indicate that we can obtain more general models of player affect if we process the model output in an ordinal fashion.
Safety and Immunogenicity of the HPV-16/18 AS04-adjuvanted Vaccine in 4–6-year-old Girls: Results to Month 12 From a Randomized Trial

Background: The burden of cervical cancer caused by human papillomavirus (HPV) is high in Latin America. The suboptimal HPV vaccination coverage in adolescents could be improved by pediatric immunization. HPV vaccination has not yet been reported in girls <9 years of age. Methods: This ongoing phase III, controlled, randomized, single-blind, multicenter study conducted in Colombia, Mexico and Panama (NCT01627561) evaluated the safety and immunogenicity of AS04-HPV-16/18 vaccine in 4–6-year-old girls. Healthy girls (randomized 1:1) received either 2 doses of AS04-HPV-16/18 vaccine (HPV group, N=74) or 1 dose of each measles-mumps-rubella and diphtheria-tetanus-acellular-pertussis vaccines (control group, N=74) 6 months apart. We report the safety and serum anti–HPV-16 and anti–HPV-18 antibodies (measured by enzyme-linked immunosorbent assay) up to 6 months postvaccination, that is, month (M) 12. Results: Injection site pain was the most frequently reported solicited local symptom in HPV vaccinees. The incidence of other solicited and unsolicited symptoms after each vaccination was similar between the HPV and control group. Until M12, 1 girl in the HPV group and 2 in the control group reported serious adverse events; all serious adverse events were assessed as unrelated to study vaccines. No potential immune-mediated diseases were identified. All girls seroconverted for both antigens after 2 doses of AS04-HPV-16/18. In initially seronegative girls, anti–HPV-16 geometric mean concentrations were 20080.0 enzyme-linked immunosorbent assay units (EU)/mL at M7 and 3246.5 EU/mL at M12; anti–HPV-18 geometric mean concentrations were 10621.8 EU/mL at M7 and 1216.6 EU/mL at M12. Conclusions: Two-dose vaccination with AS04-HPV-16/18 was well tolerated and induced adequate antibody responses in 4–6-year-old girls.
The role of evidence-based therapy relationships on treatment outcome for adults with trauma: A systematic review

ABSTRACT Objective: The purpose of this paper was to systematically review and synthesize the empirical literature on the effects of evidence-based therapy relationship (EBR) variables in the psychological treatment for adults who experienced trauma-related distress. Method: Studies were identified using comprehensive searches of PsycINFO, Medline, Published International Literature on Traumatic Stress, and Cumulative Index to Nursing and Allied Health Literature databases. Included in the review were articles published between 1980 and 2015, in English that reported on the impact of EBRs on treatment outcome in clinical samples of adult trauma survivors. Results: Nineteen unique studies met inclusion criteria. The bulk of the studies were on therapeutic alliance and the vast majority found that alliance was predictive of or associated with a reduction in various symptomotology. Methodological concerns included the use of small sample sizes, little information on EBRs beyond alliance as well as variability in its measurement, and non-randomized assignment to treatment conditions or the lack of a comparison group. Conclusions: More research is needed on the roles of client feedback, managing countertransference, and other therapist characteristics on treatment outcome with trauma survivors. Understanding the role of EBRs in the treatment of trauma survivors may assist researchers, clinicians, and psychotherapy educators to improve therapist training as well as client engagement and retention in treatment.
Association between Maximal Aerobic Capacity and Psychosocial Factors in Adults With Moderate-to-Severe Asthma

Background. The symptoms of asthma impair health-related quality of life (HRQoL), increase anxiety and depression and may keep subjects from engaging in physical exercise. Physical inactivity has been related to poor asthma outcomes; however, the association between physical fitness and psychosocial disorders remains poorly understood. Objective. To verify the association between aerobic capacity, HRQoL, and psychological distress in adults with moderate or severe persistent asthma who were clinically stable. Methods. Eighty-eight participants (68 females) with either moderate or severe persistent asthma (age range, 20–60 years) who were under medical treatment for at least 6 months and considered clinically stable were studied. Participants were evaluated on two non-consecutive days. On the first day, the HRQoL, depression and anxiety levels and pulmonary function were assessed. On the second day, subjects underwent cardiopulmonary exercise testing. Results. Using the agglomerative cluster approach, two clusters were identified: 21 participants (24%) were grouped in Cluster 1, and 67 (76%) were grouped in Cluster 2. Asthmatic subjects from Cluster 1 exhibited increased aerobic capacity, better HRQoL and lower depression levels than did subjects in Cluster 2 (p < .05). No difference was observed between the clusters with respect to gender, age, body mass index (BMI) or pulmonary function (p > .05). The discriminant function model exhibits good accuracy (R2 = 0.79) and predicted 93% of the case allocations. Conclusion. Our results suggest an association between reduced exercise capacity, low HRQoL and increases in depressive symptoms in clinically stable asthmatic subjects. These results suggest the need to assess physical fitness and psychosocial distress during asthma treatment and the importance of a multidisciplinary approach.
Barriers to Swift, Even Flow in the Internal Supply Chain of Perioperative Surgical Services Department: A Case Study

This research analyzes the internal service supply chain of a perioperative surgical services department of a nonacademic community hospital using the theory of swift and even flow as a theoretical lens. Performance data were gathered using an in-depth case study and it was determined that the swift and even flow constructs did affect flow speed and variance, but did not account for all the effects observed. To understand the need for departments to coordinate their efforts with each other and how this affected flow, further analysis was conducted using insights from Pagell's (2004) theory of internal integration and Gittell's (2002) research about coordinating mechanisms. The findings suggest the need to incorporate a variable measuring supply chain coordination into the theory of swift and even flow.
Police Managers’ Self-Control and Support for Organizational Justice

Recent policing research has identified a positive relationship between line-level officers’ perceptions of organizational justice and their adherence to agency goals and job satisfaction. However, we have little understanding of the factors that are related to police managers’ support for organizational justice when interacting with employees. We collected survey data from a sample of U.S. command-level officers (N = 211) who attended a training program in a southern state to address this gap in the literature. The anonymous survey was administered in-person to participating command-level police officers prior to their training program. Our multivariate regression analysis revealed that police managers who reported higher levels of self-control were more supportive of organizational justice (b = .26, p < .01). Additionally, police managers who reported higher quality relationships with their colleagues expressed greater support for organizational justice (b = .02, p = .02). Respondents’ self-legitimacy was not significantly associated with their support for organizational justice. This study contributes to the organizational justice literature by presenting the first analysis that links police commanders’ self-control to support for organizational justice within their management practices. The findings help pinpoint the types of individuals who may be best equipped to be fair police managers.
Beyond pathways: genetic dissection of tocopherol content in maize kernels by combining linkage and association analyses

Summary Although tocopherols play an important role in plants and animals, the genetic architecture of tocopherol content in maize kernels has remained largely unknown. In this study, linkage and association analyses were conducted to examine the genetic architecture of tocopherol content in maize kernels. Forty‐one unique quantitative trait loci (QTLs) were identified by linkage mapping in six populations of recombinant inbred lines (RILs). In addition, 32 significant loci were detected via genome‐wide association study (GWAS), 18 of which colocalized with the QTLs identified by linkage mapping. Fine mapping of a major QTL validated the accuracy of GWAS and QTL mapping results and suggested a role for nontocopherol pathway genes in the modulation of natural tocopherol variation. We provided genome‐wide evidence that genes involved in fatty acid metabolism, chlorophyll metabolism and chloroplast function may affect natural variation in tocopherols. These findings were confirmed through mutant analysis of a particular gene from the fatty acid pathway. In addition, the favourable alleles for many of the significant SNPs/QTLs represented rare alleles in natural populations. Together, our results revealed many novel genes that are potentially involved in the variation of tocopherol content in maize kernels. Pyramiding of the favourable alleles of the newly elucidated genes and the well‐known tocopherol pathway genes would greatly improve tocopherol content in maize.
The mental well-being of Central American transmigrant men in Mexico

ABSTRACT To understand the mental health status of Central American migrant men travelling through Mexico to the U.S., we analysed the association between migration-related circumstances/stressors and psychological disorders. In-person interviews and a psychiatric assessment were conducted in 2010 and 2014 with 360 primarily Honduran transmigrant young adult males. The interviews were conducted at three Casas del Migrante (or migrant safe houses) in the migration-corridor cities of Monterrey, and Guadalupe, Nuevo Leon; and Saltillo, Coahuila. The results indicated high levels of migration-related stressors including abuse and a high prevalence of major depressive episodes (MDEs), alcohol dependency, and alcohol abuse. Nested logistic regression models were used to separately predict MDEs, alcohol dependency, and alcohol abuse, assessing their association with migration experiences and socio-demographic characteristics. Logistic regression models showed that characteristics surrounding migration (experiencing abuse, migration duration, and attempts) are predictive of depression. Alcohol dependency and abuse were both associated with marital status and having family/friends in the intended U.S. destination, while the number of migration attempts also predicted alcohol dependency. The results provide needed information on the association between transit migration through Mexico to the U.S. among unauthorised Central American men and major depressive disorder and alcohol abuse and dependency.
Crystalline Character and Microhardness of Gamma‐Irradiated and Thermally Treated UHMWPE

Relationships between Vickers microhardness, x‐ray and differential scanning calorimetry (DSC) crystallinity, x‐ray long period, and melting points were determined for ultrahigh molecular‐weight polyethylene (UHMWPE) of various histories (as‐produced, irradiated, annealed, and remelted). It was shown that the microhardness responds very sensitively to both the irradiation conditions (total radiation dose, radiation dose rate) and the thermal treatment (annealing below the melting temperature, remelting). As microhardness reflects the yield point parameters, the results show that not only the total dose, but also the irradiation dose rate has a considerable influence on mechanical properties of UHMWPE. It was demonstrated that neither x‐ray nor DSC results are so sensitive to treatment as the microhardness results. The most important differences in properties were found between remelted samples and those thermally untreated or annealed.
From Bulk to Monolayer MoS2: Evolution of Raman Scattering

Molybdenum disulfide (MoS2) is systematically studied using Raman spectroscopy with ultraviolet and visible laser lines. It is shown that only the Raman frequencies of $ E_{2{\rm g}}^1 $ and $ A_{{\rm 1g}}^{} $ peaks vary monotonously with the layer number of ultrathin MoS2 flakes, while intensities or widths of the peaks vary arbitrarily. The coupling between electronic transitions and phonons are found to become weaker when the layer number of MoS2 decreases, attributed to the increased electronic transition energies or elongated intralayer atomic bonds in ultrathin MoS2. The asymmetric Raman peak at 454 cm−1, which has been regarded as the overtone of longitudinal optical M phonons in bulk MoS2, is actually a combinational band involving a longitudinal acoustic mode (LA(M)) and an optical mode ($ A_{{\rm 2u}}^{} $). Our findings suggest a clear evolution of the coupling between electronic transition and phonon when MoS2 is scaled down from three‐ to two‐dimensional geometry.
A 39.5-dB SNR, 300-Hz Frame-Rate, 56 × 70-Channel Read-Out IC for Electromagnetic Resonance Touch Panels

In this paper, a pen detection analog system for an electromagnetic resonance (EMR) touch panel is presented. An adaptive charge pump is proposed in the transmitter to drive a high current to the EMR panel and achieve a high signal-to-noise ratio (SNR) in the receiver. To compensate for the mismatches between the channels due to fabrication variations of the EMR panels and process variations of the analog front-ends (AFEs), a transmitter driver with an adaptive controller is proposed, and an AFE calibration is implemented in the transmitter and the receiver, respectively. Also, a 9-bit, 2-MS/s time-interleaved flash successive-approximation-register (SAR) analog-to-digital converter (ADC) with 3-bit flash and 6-bit SAR ADCs is proposed to increase the frame rate with small area and power consumption. External noises, such as display and charger noises, can be rejected by the differential processing, analog low-pass filter, and digital filters in the digital signal processor (DSP). This read-out integrated circuit is implemented in a 0.18-μm Bipolar-CMOS-DMOS (BCD), and the die area is ${\text{40 mm}}^{\text{2}}$ including DSP and ADCs. The power consumptions are 110 and 45 mW in the transmitter and receiver modes, respectively. The SNR is about 39.5 dB and the frame rate is about 300 Hz in the 56 × 70 touch panel.
Enhancing cytochrome P450‐mediated non‐natural cyclopropanation by mutation of a conserved second‐shell residue

Engineered cytochrome P450s are emerging as powerful synthetic tools due to their ability catalyze non‐native metallocarbenoid and ‐nitrenoid insertion reactions. P450‐mediated cyclopropanation has garnered particular interest due to the high selectivity demonstrated by engineered scaffolds and their application towards the synthesis of therapeutic agents. We previously reported that mutation of a conserved, first‐shell heme‐ligating Cys to Ser led to significant improvements in cyclopropanation activity in a model enzyme, P450BM3h. Here, we demonstrate that mutation of a ubiquitously conserved second‐shell Phe (F393) to His or Ala, provides complementary increases in the P450 heme reduction potential and conversion to cyclopropanation products when compared to first‐shell Cys to Ser mutations. Furthermore, we show that these mutations confer improved non‐natural catalysis in 4 diverse P450 scaffolds.
Impact of Selenium Addition to Animal Feeds on Human Selenium Status in Serbia

Research conducted during the 1980s demonstrated Se deficiency in humans. Increased inclusion of selenium in animal feeds started from the year 2000 onwards. The aim of this study was to estimate the effects of selenium inclusion in animal feeds on human selenium status and dietary habits of the Serbian population related to food of animal origin. Plasma selenium concentration in healthy adult volunteers, including residents of one of the regions with the lowest (Eastern Serbia, n = 60) and of one of the regions with the highest Se serum levels reported in the past (Belgrade, n = 82), was determined by hydride generation atomic absorption spectrometry. Multivariate analysis was employed to determine the correlation between Se plasma levels and dietary intake data derived from food frequency questionnaires and laboratory tests. The mean plasma Se level of the participants was 84.3 ± 15.9 μg/L (range: 47.3–132.1 μg/L), while 46% of participants had plasma Se levels lower than 80 μg/L. Frequency of meat, egg, and fish consumption was significantly correlated with plasma selenium level (r = 0.437, p = 0.000). Selenium addition to animal feed in the quantity of 0.14 mg/kg contributed to the improvement of human plasma selenium levels by approximately 30 μg/L.
A pilot-scale nonwoven roll goods manufacturing process reduces microbial burden to pharmacopeia acceptance levels for non-sterile hygiene applications

A total of seven source fiber types were selected for use in the manufacturing of nonwoven roll goods: polyester; polypropylene; rayon; greige cotton from two sources; mechanically cleaned greige cotton; and scoured and bleached cotton. The microbial burden of each source fiber was measured as a preliminary assessment of microbial contamination using heterotrophic spread plate counts. Greige cotton fibers exhibited the highest levels of total microbial contamination, which were reduced by both storage time and trash removal in the form of mechanical cleaning. Changes in microbial burden levels were measured at each step in the nonwoven manufacturing process. The hydroentanglement process resulted in the greatest overall reduction in microbial burden with no detectable levels of aerobic microbial contamination present on any of the final hydroentangled roll goods regardless of the source fiber. No detectable levels of aerobic microbial regrowth were observed on any fabrics despite storage time or ambient storage conditions. Analysis of suspended solids present in hydroentanglement effluents collected during fabric production revealed significantly less suspended solids from synthetic fibers compared to all cotton fiber types. The study provided insight and potential guidelines that could be incorporated into a nonwoven processing line to ensure specific sterility requirements are met for various converters in end-uses such as hygiene and medical applications.
Resource Allocation for D2D Communications Underlaying a NOMA-Based Cellular Network

This letter investigates the power control and channel assignment problem in device-to-device (D2D) communications underlaying a non-orthogonal multiple access (NOMA) cellular network. With the successive interference cancellation decoding order constraints, our target is to maximize the sum rate of D2D pairs while guaranteeing the minimum rate requirements of NOMA-based cellular users. Specifically, the optimal conditions for power control of cellular users on each subchannel are derived first. Then, based on these results, we propose a dual-based iterative algorithm to solve the resource allocation problem. Simulation results validate the superiority of proposed resource allocation algorithm over the existing orthogonal multiple access scheme.
The social class gradient in health in Spain and the health status of the Spanish Roma

ABSTRACT Objective. To determine the social class gradient in health in general Spain population and the health status of the Spanish Roma. Design. The National Health Survey of Spanish Roma 2006 (sample size = 993 people; average age: 33.6 years; 53.1% women) and the National Health Surveys for Spain 2003 (sample size: 21,650 people; average age: 45.5 years; 51.2% women) and 2006 (sample size: 29,478 people; average age: 46 years; 50.7% women) are compared. Several indicators were chosen: self-perceived health, activity limitation, chronic diseases, hearing and sight problems, caries, and obesity. Analysis was based on age-standardised rates and logistic regression models. Results. According to most indicators, Roma's health is worse than that of social class IV–V (manual workers). Some indicators show a remarkable difference between Roma and social class IV–V: experiencing three or more health problems, sight problems, and caries, in both sexes, and hearing problems and obesity, in women. Conclusion. Roma people are placed on an extreme position on the social gradient in health, a situation of extreme health inequality.
An Aggregate Signature Based Trust Routing for Data Gathering in Sensor Networks

An Aggregate Signature based Trust Routing (ASTR) scheme is proposed to guarantee safe data collection in WSNs. In ASTR scheme, firstly, the aggregate signature approach is used to aggregate data and keep data integrity. What is more important, a light aggregate signature based detour routing scheme is proposed to send abstract information which includes the data sending time and ID of data, nodes’ ID to the sink over different paths which can verify whether the data reaches the sink safely. In addition, the trust of a path is evaluated according to the success rate of the path. The trust of paths susceptible to frequent attack will be lowered and the path with high trust will be selected for data routing to avoid data gathering through low trust path and thereby increase the success rate of data gathering. Our comprehensive performance analysis has shown that, the ASTR scheme is able to effectively ensure an increase in success rate of data transmission by 23.23%, reduce the data amount loaded by the node by 53.59%, reduce the redundant data by 41.70%.