Miracle-dz/UniFAR-FTUs huggingface dataset:
Reducing memory latency via non-blocking and prefetching caches

Non-blocking caches and prefetehing caches are two techniques for hiding memory latency by exploiting the overlap of processor computations with data accesses. A nonblocking cache allows execution to proceed concurrently with cache misses as long as dependency constraints are observed, thus exploiting post-miss operations, A prefetching cache generates prefetch requests to bring data in the cache before it is actually needed, thus allowing overlap with premiss computations. In this paper, we evaluate the effectiveness of these two hardware-based schemes. We propose a hybrid design based on the combination of these approaches. We also consider compiler-based optimization to enhance the effectiveness of non-blocking caches. Results from instruction level simulations on the SPEC benchmarks show that the hardware prefetching caches generally outperform nonblocking caches. Also, the relative effectiveness of nonblocklng caches is more adversely affected by an increase in memory latency than that of prefetching caches,, However, the performance of non-blocking caches can be improved substantially by compiler optimizations such as instruction scheduling and register renaming. The hybrid design cm be very effective in reducing the memory latency penalty for many applications.
Perinatal chikungunya in twins

We report a case of vertically transmitted chikungunya infection in heterozygous twin neonates presenting as seizures, encephalopathy, midfacial hyperpigmentation, anemia, and thrombocytopenia. This could be considered as a rare cause of neonatal seizure and identification would help in appropriate management.
Articles: Recognizing Contextual Polarity: An Exploration of Features for Phrase-Level Sentiment Analysis

Many approaches to automatic sentiment analysis begin with a large lexicon of words marked with their prior polarity (also called semantic orientation). However, the contextual polarity of the phrase in which a particular instance of a word appears may be quite different from the word's prior polarity. Positive words are used in phrases expressing negative sentiments, or vice versa. Also, quite often words that are positive or negative out of context are neutral in context, meaning they are not even being used to express a sentiment. The goal of this work is to automatically distinguish between prior and contextual polarity, with a focus on understanding which features are important for this task. Because an important aspect of the problem is identifying when polar terms are being used in neutral contexts, features for distinguishing between neutral and polar instances are evaluated, as well as features for distinguishing between positive and negative contextual polarity. The evaluation includes assessing the performance of features across multiple machine learning algorithms. For all learning algorithms except one, the combination of all features together gives the best performance. Another facet of the evaluation considers how the presence of neutral instances affects the performance of features for distinguishing between positive and negative polarity. These experiments show that the presence of neutral instances greatly degrades the performance of these features, and that perhaps the best way to improve performance across all polarity classes is to improve the system's ability to identify when an instance is neutral.
MODELLING THE BACKSCATTERING COEFFICIENT OF SALT-AFFECTED SOILS: APPLICATION TO WADI EL-NATRUN BOTTOM, EGYPT

One of the most crucial environmental problems affecting developing countries in arid and semi-arid regions is soil salinity. Its detection using radar imaging systems is one of promising domains of remote sensing research. Detection is based essentially on the relationship between the quantity of existing salts in the soil, the soil moisture content, and the dielectric properties of this mixture. Due to the components of the mixture and their corresponding dielectric properties, backscattering of these types of soils can be modelled and monitored. Parameters influencing the radar detection of saltaffected soils are grouped into two main groups: those related to the sensor and those related to the target. Some of these parameters cause information attenuation during monitoring of the saltaffected soils; however, others give us information that help to better understand the phenomena. Some of the latter parameters can be controlled and others are imposed. Most previous studies neglected the effect of the presence of salts combined with the other parameters on the backscattering coefficient. In this paper, we present the salinity effect on the calculation of the backscattering coefficient using several backscattering models. The results show that the high dielectric constant, due to the extensive presence of salts, has a significant effect on the backscattering value. To validate the modelling approach with actual data, four RADARSAT-1 satellite images in standard modes were selected for the area of Wadi El-Natrun, Egypt, where fieldwork was conducted simultaneously with some of the RADARSAT-1 image acquisitions.
How to Turn the Fate of Old Industrial Areas: A Comparison of Cluster-Based Renewal Processes in Styria and the Saarland

The aim of this paper is to explore the role of regional innovation systems and clusters in the economic recovery of old industrial regions. We draw a distinction between three types of cluster-based renewal: an innovation-oriented adjustment of mature clusters (incremental change); the emergence of new agglomerations in established industries (diversification); and the rise of knowledge-intensive and high-technology activities (radical change). In the empirical part of the paper we compare cluster-based recovery processes in the regions of Styria and the Saarland. It is shown that Styria rebuilt its regional innovation system more successfully, enabling the innovation-oriented adjustment of a mature cluster, the rise of a new cluster in an established industry, and the emergence of knowledge-intensive activities. In the Saarland, in contrast, the regional innovation system has been more specialised, which has resulted in weak performance with respect to incremental change and diversification and high performance regarding radical change.
IRON DEFICIENCY ANEMIA IN PREGNANT MOTHERS AS A CAUSE OF POOR MATERNAL HEALTH IN RURAL INDIA

Worldwide Iron deficiency anemia (IDA) affects approximately 25% population and in India it affects 80% of pregnant mothers. A prospective observational study was conducted to know relationship between IDA in pregnancy and its effects on maternal health during pregnancy, labour and postpartum. Pregnant mothers with singleton pregnancy with gestational age > 36 weeks were selected and were divided into two groups. Women with Hb >10 gm% classified in nonanemic group and those with Hb<10 were classified in anemic group. It was further confirmed by serum ferritin levels. Both groups were followed till delivery and effects of anemia on maternal health were studied. Number of vaginal deliveries, instrumental deliveries and cesarean section (LSCS) were similar in both groups but more anemic mothers required induction of labour. More anemic mothers had PPH 5(6.09%) as compared to 2(2.56%) in non anemic group. Only anemic mothers after PPH required blood transfusion 3(3.65%). 18 (21.95%) mothers in anemic group had other morbid symptoms whereas in nonanemic group 3(3.84%) had similar symptoms. The study emphasize that IDA is widely prevalent in pregnant mothers and is associated with life threatening conditions during pregnancy and childbirth. Prevention of IDA during pregnancy can prevent many serious maternal complications.
Nanoparticles of Copper Stimulate Angiogenesis at Systemic and Molecular Level

Copper is a key element affecting blood vessel growth and muscle development. However, the ions released from Cu salts are toxic. Given their specific physicochemical properties, nanoparticles of Cu (NanoCu) may have different bioactivity and affect the development of blood vessel and muscles in a different manner than Cu salts. The objective of the study was to evaluate the influence of NanoCu on embryo development and angiogenesis at the systemic and molecular level, in experiments using a chick embryo model. Fertilized chicken eggs were divided into a control group, and groups injected with a placebo, CuSO4 or NanoCu. Embryo development at the whole body level and molecular indices using an embryo chorioallantoic membrane model were measured during embryogenesis. The present study indicated for the first time that NanoCu have pro-angiogenic properties at the systemic level, to a greater degree than CuSO4 salt. The properties of NanoCu were confirmed at the molecular level, demonstrating significant effects on mRNA concentration and on mRNA gene expression of all pro-angiogenic and pro-proliferative genes measured herein.
Properties of MPC for Max-Plus-Linear Systems

Model predictive control (MPC) is a very popular controller design method in the process industry. One of the main advantages of MPC is that it can handle constraints on the inputs and outputs. Usually MPC uses linear discrete-time models. Recently, we have extended this framework to max-plus-linear discrete event systems. In this paper, we further explore this topic. More specifically, we focus on implementation and timing aspects, closed-loop behavior and tuning rules for model predictive control of max-plus-linear (MPL) systems.
A Survey of Tool Use in Modeling Education

We present the results of a survey of tool use in software modeling education conducted from December 2016 to March 2017. The survey was conducted among 150 professors who taught modeling in 30 countries from all regions of the world. Professors reported using 32 modeling tools. Top motivations for choosing tools are simplicity of learning and installing, as well as the tools being free and supporting the most important notations. Top complaints about tools included not interacting with other tools, not supporting sufficient modeling aspects, and being complex to use. Seven of the tools were used by more than one professor as their main tools, and we analyzed these in more depth. Among these 7, lack of feedback about models emerged as another key weakness. The tools varied very considerably regarding which of these strengths and weaknesses they exhibited. The key lessons from the paper are a) that tool developers have many opportunities to improve their products, and b) that educators might benefit from introducing students to multiple different tools.
Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors

Despite extensive investigation over the past decade, the mechanism of target cell lysis by cytolytic T lymphocytes (CTL) remains obscure (for recent reviews, see Perlmann & Cerottini 1979, Berke 1980). Since lysis is known to require close contact between CTL and target cells, one promising approach to this problem is the search for surface molecules on CTL which may play a role in antigen recognition and/or the expression of cytolytic activity. With the recent availability of monoclonal antibodies, it has become possible to identify such potentially interesting surface molecules by virtue of the ability of a corresponding monoclonal antibody to block CTL activity in the absence of complement. Using such an approach, two possible "functional" molecular complexes on CTL populations have been recently identified: Lyt-2/3 (Nakayama et al. 1979, Shinohara et al. 1979) and LFA-1 (Davignon et al. 1981). At least two limitations to the interpretation of these antibody blocking experiments can be invoked. Firstly, blocking was carried out on polyclonal CTL populations activated by lectins or alloantigens; thus it is not possible to
Two-Photon Imaging during Prolonged Middle Cerebral Artery Occlusion in Mice Reveals Recovery of Dendritic Structure after Reperfusion

Filament occlusion of the middle cerebral artery (MCA) is a well accepted animal model of focal ischemia. Advantages of the model are relatively long occlusion times and a large penumbra region that simulates aspects of human stroke. Here, we use two-photon and confocal microscopy in combination with regional measurement of blood flow using laser speckle to assess the spatial relationship between the borders of the MCA ischemic territory and loss of dendrite structure, as well as the effect of reperfusion on dendritic damage in adult YFP (yellow fluorescent protein) and GFP (green fluorescent protein) C57BL/6 transgenic mice with fluorescent (predominantly layer 5) neurons. By examining the spatial extent of dendritic damage, we determined that 60 min of MCA occlusion produced a core with severe structural damage that did not recover after reperfusion (begins ∼3.8 mm lateral to midline), a reversibly damaged area up to 0.6 mm medial to the core that recovered after reperfusion (penumbra), and a relatively structurally intact area (∼1 mm wide; medial penumbra) with hypoperfusion. Loss of structure was preceded by a single ischemic depolarization 122.1 ± 10.2 s after occlusion onset. Reperfusion of animals after 60 min of ischemia was not associated with exacerbation of damage (reperfusion injury) and resulted in a significant restoration of blebbed dendritic structure, but only within ∼0.6 mm lateral of the dendritic damage structural border. In summary, we find that recovery of dendritic structure can occur after reperfusion after even 60 min of ischemia, but is likely restricted to a relatively small penumbra region with partial blood flow or oxygenation.
The Changing World of the Teacher

G. L. Bach, the former dean of the graduate School of Industrial Administration of Carnegie Tech and now a professor there, recently quoted Edward Tallas as saying that in each century since 1650, man has roughly doubled his knowledge of the world and of mankind. Bach went on to say that we will learn as much more about the world in the rest of this century as in all previous history, that this kind of progress indicates that the changes during the next 25 years will be nearly as great, perhaps even greater, than those of the first half of our century.1
Jacques Lacan, Barred Psychologist

This paper reviews a series of contradictions between the discipline of psychology and the work of Jacques Lacan. Psychology here is the academic and professional domain of theory and practice developed in Western, specifically Anglo-US American, culture to describe and explain behavioural and mental processes. Lacan is characterized with reference to the elaboration of his theoretical and clinical work, with the focus primarily on his own writings. The main argument is that there is a fundamental incompatibility between Lacan's work and psychological views of the individual subject, and therefore attempts to assimilate the two traditions are misconceived. This means that psychologists looking to Lacan for answers must question underlying assumptions about theory and methodology in their discipline if they are to take his work seriously. The incompatibility between Lacan and psychology also has important consequences for clinical psychologists who may wish to adopt ideas from the Lacanian tradition, for it highlights the dangers that psychology holds for psychoanalysis if psychological theories and methodologies are taken on good coin. The motif of Lacan as `barred psychologist' is designed to emphasize these arguments as well as the distinctive account of the human subject that his work entails.
Random and Systematic Error Effects of Insomnia on Survey Behavior

Insomnia is a prevalent experience among employees and survey respondents. Drawing from research on sleep and self-regulation, we examine both random (survey errors) and systematic (social desirability) effects of research participant insomnia on survey responses. With respect to random effects, we find that insomnia leads to increased survey errors, and that this effect is mediated by a lack of self-control and a lack of effort. However, insomnia also has a positive systematic effect, leading to lower levels of social desirability. This effect is also mediated by self-control depletion and a lack of effort. In supplemental analyses, we find that psychometric side effects of random and systematic error introduced by individuals high in insomnia negatively affect internal consistency estimates and measurement invariance on various organizational measures. Results were replicated across two studies, with alternative operationalizations of survey errors and social desirability and some alternative explanations examined. These findings suggest sleep may be a key methodological issue for conducting survey research. Recommendations from the sleep and self-regulation literature regarding potential strategies for counteracting the effect of insomnia on survey responses are discussed.
The Arrow of Time and the Cycle of Time: Concepts of Change, Cognition, and Embodiment

In this target article, I explore the thesis that both the natural and human sciences are undergoing—however gradually and reluctantly—a deep and broad paradigm shift. This shift is away from foundational, objectivist, atomist, nondirectional mechanistic category systems and toward interpretational, holistic, relational-dialectical, directional organic category systems. The contextual influence of each of these category systems on understandings of change (development), cognition, and personality is examined both historically and from a contemporary perspective across a wide band of scientific disciplines. The Arrow of Time is a deep metaphor entailing a relational field of both nonclosed cycles (spirals) and direction. The Arrow of Time metaphor emerges from the organic narrative. Within the context of this metaphor, and the broader organic metaphor that forms the wider conceptual context, development is understood as entailing both direction and variation. Within the organic metaphor, cognition and pers.
Waiting time to pregnancy and pregnancy outcome among Danish workers in the textile, clothing, and footwear industries

Delay in conception and pregnancy outcome among Danish workers in the textile, clothing and footwear industries. Schaumburg, I. and Boldsen, J. L. (Institute of Community Health, University of Odense, J. B. Winsløws Vej 17, DK 5000 Odense C, Denmark). The relationship between time from planned to achieved pregnancy and pregnancy outcome has been studied in a group of 18,658 workers in the textile, clothing and footwear industries. Information on pregnancy outcome and delay in conception in the period 1979–84 was collected by self administered questionnaires in 1985. The response rate was 70.3%. During the study period there had been 5,171 live births and 70S spontaneous abortions. Information on delay in conception was collected in broad categories. The data were analysed by means of a newly developed statistical parametric model in order to collect all possible information from the highly grouped data. Median waiting time before a pregnancy which ended in spontaneous abortion was 1.68 times longer than median waiting time before a pregnancy leading to a live birth. There seems to be a correlation between the length of the waiting time and abortion.
Variable Neighborhood Search for Extremal Graphs. 10. Comparison of Irregularity Indices for Chemical Trees

Chemical graphs, as other ones, are regular if all their vertices have the same degree. Otherwise, they are irregular, and it is of interest to measure their irregularity both for descriptive purposes and for QSAR/QSPR studies. Three indices have been proposed in the literature for that purpose: those of Collatz-Sinogowitz, of Albertson, and of Bell's variance of degrees. We study their properties for the case of chemical trees. Structural conjectures are generated with the system AutoGraphiX, and most of them proved later by mathematical means. Analytical expressions for extremal values are obtained, and extremal graphs are characterized for the two last indices.
Loblolly Pine Growth Patterns on Reclaimed Mineland: Allometry, Biomass, and Volume

Surface lignite coal mines in east Texas are commonly reforested using loblolly pine (Pinus taeda L.) following mining and reclamation activities. Due to the nature of such an extreme disturbance, altered growth patterns, growth rates, and productivity could be expected. We destructively sampled above- and belowground tissue to develop prediction equations specific to these sites. These prediction equations differed statistically from those found in the literature regarding unmined land. At the stand level, biomass and volume productivity appeared similar with young stands on reclaimed mineland performing slightly poorer than similarly managed unmined sites. Allometric partitioning of above- and belowground biomass differed statistically from the unmined allometric model previously studied. The allometric pattern on reclaimed mineland indicated greater partitioning of biomass belowground for young stands of low quadratic mean diameter relative to unmined stands. Older stands on reclaimed mineland exhibited no allometric partitioning differences from unmined stands, indicating the normal allometric pattern is resumed for stands greater than 10 years of age.
Prognostic value of cellular proliferation and histologic grade in follicular lymphoma.

The clinical usefulness of histologic grading in follicular lymphoma (FL) is controversial and is further compromised by the subjective nature and poor reproducibility of most systems in current use. Therefore, we decided to objectively evaluate the importance of cellular proliferation in FL, along with the current grading systems. We studied 106 patients with FL who were uniformly staged and aggressively treated. A proliferative index (PI) was determined quantitatively using an automated image analyzer and a new Ki-67 antibody that stains archival paraffin tissues. The cases were also subclassified according to the Berard, Rappaport, Luke-Collins, and Jaffe methods, and survival analysis was performed. Patients with a low PI (< 40%) had a significantly longer overall survival (OS) than those with a high PI (> or = 40%), but the PI did not predict failure-free survival (FFS). The mean PI correlated well with the subgroups in each of the various classifications. All four of the classification methods were predictive of OS, but only the Berard method appeared to predict FFS and suggest that a proportion of patients with FL may be curable. In multivariate analysis, histologic classification was the only independent predictor of OS (Berard method: relative risk, 3.1) and the International Prognostic Index was the only independent predictor of FFS (relative risk, 2.3). We conclude that the Berard method for grading of FL is clinically useful and, along with the International Prognostic Index, should be included in future clinical studies of FL. The measurement of cellular proliferation does not appear to add additional useful information in FL.