Miracle-dz/UniFAR-FTUs huggingface dataset:
Weekly work engagement and performance: A study among starting teachers

This study among 54 Dutch teachers tested a model of weekly work engagement. On the basis of theories about the motivational potential of job resources, we predicted that teachers' weekly job resources are positively related to their week-levels of work engagement, and that week-level work engagement is predictive of week-level performance. In addition, we hypothesized that momentary work engagement has a positive, lagged effect on next week's job resources. Teachers were asked to fill in a weekly questionnaire every Friday during 5 consecutive weeks. Results of multi-level analyses largely confirmed our hypotheses, by showing that week-levels of autonomy, exchange with the supervisor, and opportunities for development (but not social support) were positively related to weekly engagement, which, in turn, was positively related to weekly job performance. Moreover, momentary work engagement was positively related to job resources in the subsequent week. These findings show how intra-individual variability in employees' experiences at work can explain weekly job performance.
Biochemical and Molecular Characterization of a Flavonoid 3-O-glycosyltransferase Responsible for Anthocyanins and Flavonols Biosynthesis in Freesia hybrida

The glycosylation of flavonoids increases their solubility and stability in plants. Flowers accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar flavonoid glycosyltransferases (UFGTs). In our previous study, a cDNA clone (Fh3GT1) encoding UFGT was isolated from Freesia hybrida, which was preliminarily proved to be invovled in cyanidin 3-O-glucoside biosynthesis. Here, a variety of anthocyanin and flavonol glycosides were detected in flowers and other tissues of F. hybrida, implying the versatile roles of Fh3GT1 in flavonoids biosynthesis. To further unravel its multi-functional roles, integrative analysis between gene expression and metabolites was investigated. The results showed expression of Fh3GT1 was positively related to the accumulation of anthocyanins and flavonol glycosides, suggesting its potential roles in the biosynthesis of both flavonoid glycosides. Subsequently, biochemical analysis results revealed that a broad range of flavonoid substrates including flavonoid not naturally occurred in F. hybrida could be recognized by the recombinant Fh3GT1. Both UDP-glucose and UDP-galactose could be used as sugar donors by recombinant Fh3GT1, although UDP-galactose was transferred with relatively low activity. Furthermore, regiospecificity analysis demonstrated that Fh3GT1 was able to glycosylate delphinidin at the 3-, 4-′, and 7- positions in a sugar-dependent manner. And the introduction of Fh3GT1 into Arabidopsis UGT78D2 mutant successfully restored the anthocyanins and flavonols phenotypes caused by lost-of-function of the 3GT, indicating that Fh3GT1 functions as a flavonoid 3-O-glucosyltransferase in vivo. In summary, these results demonstrate that Fh3GT1 is a flavonoid 3-O-glycosyltransferase using UDP-glucose as the preferred sugar donor and may involve in flavonoid glycosylation in F. hybrida.
The indirect object construction in English: an informational approach

Cet article est base sur les constatations d'une etude de corpus sur l'anglais australien contemporain. L'A. explique que l'alternance dative (association entre les phrases a objet indirect et celles contenant les prepositions to et for) ne peut pas etre expliquer en faisant appelle seulement aux notions semantiques/pragmatiques telles que l'affectivite, l'objectivite-indirecte ou la distance iconique
Repression of synthesis of the vitamin B12 receptor in Escherichia coli

Growth of Escherichia coli K-12 strains in the presence of the vitamin cyanocobalamin (B12) resulted in an 80 to 90% reduction in B12 uptake activity of washed cells. Coincident with the decline in uptake activity was the depression of B12-binding activity in energy-poisoned cells, suggesting that growth in B12 resulted in the repression of synthesis of the B12 receptor protein in the outer membrane. Growth in the presence of B12 led to marked reduction in sensitivity to the E colicins, whose adsorption to cells requires the B12 receptor, and to a decrease in the amount of a band on electropherograms of outer membrane proteins. That polypeptide was also missing from mutants altered at btuB, the locus encoding the B12 receptor. Addition of B12 to growing cultures resulted in the exponential decline in specific activity of B12 uptake, as expected for dilution of functional receptors by further growth. Repression of receptor synthesis appears to be regulated by the level of intracellular, rather than extracellular, B12 and is separate from the regulation of the methionine biosynthetic pathway. Mutants altered in btuC, which are defective in accumulation and retention of B12, exhibit a much lower degree of repressibility.
Primary and secondary school teachers in France: changes in identities and professionalization

Teacher professionalization is a recent field of study in France that has developed in connection with the creation of the Instituts Universitaires de Formation des Maîtres (IUFMs) and other changes that have brought primary and secondary teachers into closer relation. In order to help the reader understand the traditional divisions between these two groups and recent trends towards unification, we first present historical differences in their development as separate corps, their training and their modes of unionization. We then proceed to analyse the political turning point of 1989, date of the creation of the IUFMs which introduced a similar curriculum for teachers of each degree on the basis of officially specified fundamental skills, as well as leading to the reconstitution of teachers' unions. Finally, we examine the effects of recent moves toward professionalization on the rationalization of teachers' knowledge and skills, the relationship between training and professional activity and teachers' socialization.
The future of benefit-cost analyses of the Clean Air Act.

This review examines the first two studies conducted pursuant to a Congressional mandate that the U.S. Environmental Protection Agency analyze the effects of the Clean Air Act on the "public health, economy, and the environment of the United States. " While these studies indicate that overall, the nation received good value for the resources it invested in improving air quality over the past three decades, we don't know if even higher value could have been obtained by changing or eliminating certain potentially inefficient elements. The review focuses on the critical policy and technical choices made in the analyses, including the selection of the appropriate baseline and the level of disaggregation for the studies. It is proposed that a potential third analysis focus on potential new policies not yet mandated by law or regulation. It is also proposed that the next study fill in key information gaps, expand the benefit categories, and incorporate new research on topics such as mortality and morbidity benefits, cost uncertainties, and others.
Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations

One important goal of asthma treatment is to reduce exacerbations. The current authors investigated if the use of sputum cell counts to guide treatment would achieve this goal. A total of 117 adults with asthma were entered into a multicentre, randomised, parallel group-effectiveness study for two treatment strategies over a 2-yr period. In one strategy (the clinical strategy: CS) treatment was based on symptoms and spirometry. In the other (the sputum strategy: SS) sputum cell counts were used to guide corticosteroid therapy to keep eosinophils ≤2%; symptoms and spirometry were used to identify clinical control, exacerbations and other treatments. Patients were blind to sputum cell counts in both strategies and physicians were blind in the CS, thus removing bias. First, the minimum treatment to maintain control was identified in 107 patients (Phase 1) and then this treatment was continued (Phase 2) for the remaining of the 2 yrs. The primary outcomes were the relative risk reduction for the occurrence of the first exacerbation in Phase 2 and the length of time without exacerbation. The current authors also examined the type and severity of exacerbations and the cumulative dose of inhaled steroid needed. The duration and number of exacerbations in Phase 1 were similar in both groups. In Phase 2 there were a 126 exacerbations of which 79 occurred in the CS (62.7%) and 47 (37.3%) in the SS groups. The majority of the 126 exacerbations (101; 80.1%) were mild. The majority of the 102 exacerbations, where sputum examination was performed before any treatment (n = 70), were noneosinophilic. In the SS patients, the time to the first exacerbation was longer (by 213 days) especially in those considered to need treatment with a long acting β2-agonist (by 490 days), the relative risk ratio was lower (by 49%), and the number of exacerbations needing prednisone was reduced (5 versus 15). This benefit was seen mainly in patients needing treatment with inhaled steroid in a daily dose equivalent to fluticasone >250 μg, and was due to fewer eosinophilic exacerbations. The cumulative dose of corticosteroid during the trial was similar in both groups. Monitoring sputum cell counts was found to benefit patients with moderate-to-severe asthma by reducing the number of eosinophilic exacerbations and by reducing the severity of both eosinophilic and noneosinophilic exacerbations without increasing the total corticosteroid dose. It had no influence on the frequency of noneosinophilic exacerbations, which were the most common exacerbations.
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1.

Leptomycin B (LMB) is a Streptomyces metabolite that inhibits nuclear export of the human immunodeficiency virus type 1 regulatory protein Rev at low nanomolar concentrations. Recently, LMB was shown to inhibit the function of CRM1, a receptor for the nuclear export signal (NES). Here we show evidence that LMB binds directly to CRM1 and that CRM1 is essential for NES-dependent nuclear export of proteins in both yeast and mammalian cells. Binding experiments with a biotinylated derivative of LMB and a HeLa cell extract led to identifying CRM1 as a major protein that bound to the LMB derivative. Microinjection of a purified anti-human CRM1 antibody into the mammalian nucleus specifically inhibited nuclear export of NES-containing proteins, as did LMB. Consistent with this, CRM1 was found to interact with NES, when assayed with immobilized NES and HeLa cell extracts. This association was disrupted by adding LMB or purified anti-human CRM1 antibody. The inhibition of CRM1 by LMB was also observed in fission yeast. The fission yeast crm1 mutant was defective in the nuclear export of NES-fused proteins, but not in the import of nuclear localization signal (NLS)-fused proteins. Interestingly, a protein containing both NES and NLS, which is expected to shuttle between nucleus and cytoplasm, was highly accumulated in the nucleus of the crm1 mutant cells or of cells treated with LMB. These results strongly suggest that CRM1 is the target of LMB and is an essential factor for nuclear export of proteins in eukaryotes.
Citizenship and Same Sex Relationships

In the UK in recent years, a dramatic growth in media concern with same sex relationships has led to the suggestion that the resulting visibility is indicative of the extent to which the intimate lives of non-heterosexuals are becoming more acceptable. In this article we question this using data drawn from the Families of Choice Project, a qualitative research project based on interviews with over a hundred non-heterosexual women and men, which highlight the ways in which they are prevented from participating as full citizens in civic, political, economic, and legal society. Using Plummer's (1995) notion of intimate citizenship, we discuss first how respondents talk about the ways in which their intimate relationships are not recognised or validated legally, economically, politically or socially. We then analyse the respondents, ideas about what policy options could be considered to include their ‘families of choice’. Finally, we argue that the family model on which most legislation and policy is based is too narrow, exclusive and inflexible to include families of choice.
Positive and Negative Self–Perceptions: Is There a Cyclical Relationship between Teachers’ and Students’ Perceptions of Effort, Strategy Use, and Academic Performance?

This study was part of a larger research program designed to investigate how effort interacts with strategy use to mediate the academic performance of successful students with learning disabilities (LD) and how teachers’ and students’ perceptions influence these relationships. The sample consisted of 46 students with LD and 46 matched students without LD and their seven teachers from Grades 6–8. A self–report survey was used to obtain an index of students’ perceptions of their effort, strategy use, academic struggles, and academic competence. Our findings indicated that students with LD with positive academic self–perceptions were more likely to work hard and to use strategies in their schoolwork than were students with LD who had negative academic self–perceptions. Teachers viewed students with LD who had positive academic self–perceptions as working equally hard and attaining similar levels of academic competence as their peers without LD. In marked contrast, students with LD who had negative academic self–perceptions were judged by their teachers as making limited effort in school and achieving at a below–average level in comparison with their peers. Findings suggested a cyclical relationship between students’ self–perceptions and their teachers’ judgments and supported the notion of a reciprocal strategy–effort interaction.
Penetration of Fosfomycin into Inflammatory Lesions in Patients with Cellulitis or Diabetic Foot Syndrome

ABSTRACT We investigated the distribution of the broad-spectrum antibiotic fosfomycin in infected soft tissue of patients with uncomplicated cellulitis of the lower extremities or diabetic foot infection using in vivo microdialysis. Our findings suggest that fosfomycin exhibits good and similar penetration into the fluid in the interstitial space in inflamed and noninflamed soft tissue in patients.
Ethnicity, Disruptiveness, and Emotional Disorder among Prison Inmates

In this exploration of mental health and disciplinary problems in prisons, we compare social history, criminal history and psychiatric diagnoses across ethnic groups and across mental health service-delivery categories on a release cohort of over 10,000 inmates, with particular attention to differences between low-rate and high-rate infractors. The data indicate that age-related variables are the most helpful in explaining variations in infraction rates across ethnic groups. However, diagnostic profiles also differ with ethnicity, and this suggests that some variations in disruptiveness can be related to differences in prevalence of pathology. In particular, the disproportionate incidence of paranoid-schizophrenia diagnoses among disturbed black inmates suggests that among some of the inmates subcultural and psychological predispositions may converge to produce prison-adjustment problems.
A colorectal cancer patient focus group develops an information package.

INTRODUCTION In order to deliver high quality care and empower cancer patients in decision-making, good quality information and communication are essential. We describe the development of an information booklet. PATIENTS AND METHODS A total of 22 colorectal cancer patients (12 male; median age, 72 years, range, 40-86 years) met on 3 occasions. Patients were asked to define their information needs and score them (1-4) according to importance. The information document was written. The second meeting involved feedback on the booklet. The modified booklet was reviewed/approved by the group before submission for local ethics committee approval prior to its distribution to other patients. RESULTS All participants felt the project a good idea. Essential information included the surgeon's individual morbidity, mortality, survival, recurrence data and details of adjuvant therapies (score = 4). Also important were type of surgery, complications and postoperative recovery (score = 3). Simple anatomical drawings were also considered important. CONCLUSIONS The booklet is now used to personalise information for all our patients and serves, in part, as a record of the key issues discussed during the consultation. The booklet has been evaluated in a randomised trial.
Bigger Is Not Always Better

We use data from the Midlife Development in the United States study to examine how sexual satisfaction, frequency, and number of partners are associated with men’s body weight. We consider five body weight categories (underweight, normal, overweight, obese I, and obese II/III), and control for potential explanatory factors including demographic characteristics, socioeconomic status, health, perceived stigmatization, and adolescent weight. Obese II/III men report significantly less sexual satisfaction and less frequent sexual activity, and a greater likelihood of having no sex partner compared to normal weight men. Physical and mental health conditions partially account for obese II/III men’s less satisfying and less frequent sex. However, the deleterious effects of obesity are suppressed by youthful weight. Obese II/III men are more likely to have been overweight adolescents, an attribute associated with more frequent and satisfying sex in adulthood. We discuss implications for the study of masculinities, and the ways that bodies and their symbolic meanings can shape men’s sexual lives.
Skeletal Muscle Insulin Resistance in Endocrine Disease

We summarize the existing literature data concerning the involvement of skeletal muscle (SM) in whole body glucose homeostasis and the contribution of SM insulin resistance (IR) to the metabolic derangements observed in several endocrine disorders, including polycystic ovary syndrome (PCOS), adrenal disorders and thyroid function abnormalities. IR in PCOS is associated with a unique postbinding defect in insulin receptor signaling in general and in SM in particular, due to a complex interaction between genetic and environmental factors. Adrenal hormone excess is also associated with disrupted insulin action in peripheral tissues, such as SM. Furthermore, both hyper- and hypothyroidism are thought to be insulin resistant states, due to insulin receptor and postreceptor defects. Further studies are definitely needed in order to unravel the underlying pathogenetic mechanisms. In summary, the principal mechanisms involved in muscle IR in the endocrine diseases reviewed herein include abnormal phosphorylation of insulin signaling proteins, altered muscle fiber composition, reduced transcapillary insulin delivery, decreased glycogen synthesis, and impaired mitochondrial oxidative metabolism.
Examining the Key Factors Affecting e-Service Quality of Small Online Apparel Businesses in Malaysia

e-Service quality (eSQ) is increasingly recognized as an important aspect, as well as the key to determining the competitive advantage and factor in the long-term retention of firms operating online. This study, therefore, is aimed at identifying the key determinants of eSQ among the small online apparel businesses in Malaysia. This study used a cross-sectional design, and data were collected from 765 customers who purchased apparel online at the point-of-purchase. Findings of this study indicate that “product information quality,” “website design,” “security and privacy,” and “expected consumer service” are the key determinants of eSQ among small online apparel businesses in Malaysia. The implication for the owner-managers of the apparel businesses in Malaysia is that they must be aware of the significance of the key eSQ indicators while designing their businesses, to attract and retain customers.
The Predictive Performance and Stability of Six Species Distribution Models

Background Predicting species’ potential geographical range by species distribution models (SDMs) is central to understand their ecological requirements. However, the effects of using different modeling techniques need further investigation. In order to improve the prediction effect, we need to assess the predictive performance and stability of different SDMs. Methodology We collected the distribution data of five common tree species (Pinus massoniana, Betula platyphylla, Quercus wutaishanica, Quercus mongolica and Quercus variabilis) and simulated their potential distribution area using 13 environmental variables and six widely used SDMs: BIOCLIM, DOMAIN, MAHAL, RF, MAXENT, and SVM. Each model run was repeated 100 times (trials). We compared the predictive performance by testing the consistency between observations and simulated distributions and assessed the stability by the standard deviation, coefficient of variation, and the 99% confidence interval of Kappa and AUC values. Results The mean values of AUC and Kappa from MAHAL, RF, MAXENT, and SVM trials were similar and significantly higher than those from BIOCLIM and DOMAIN trials (p<0.05), while the associated standard deviations and coefficients of variation were larger for BIOCLIM and DOMAIN trials (p<0.05), and the 99% confidence intervals for AUC and Kappa values were narrower for MAHAL, RF, MAXENT, and SVM. Compared to BIOCLIM and DOMAIN, other SDMs (MAHAL, RF, MAXENT, and SVM) had higher prediction accuracy, smaller confidence intervals, and were more stable and less affected by the random variable (randomly selected pseudo-absence points). Conclusions According to the prediction performance and stability of SDMs, we can divide these six SDMs into two categories: a high performance and stability group including MAHAL, RF, MAXENT, and SVM, and a low performance and stability group consisting of BIOCLIM, and DOMAIN. We highlight that choosing appropriate SDMs to address a specific problem is an important part of the modeling process.
Relations of conceptions of gender-role transgressions and gender constancy to gender-typed toy preferences.

This study examined the relations among preschoolers' gender-typed toy choice, their judgments regarding cross-gender behavior, and gender constancy. Gender-typed toy choice of 87 preschool children was assessed with a measure in which children could base their choices not only on gender but also on attractiveness. Children's judgments regarding cross-gender behavior were measured, and their level of cognitive constancy was assessed. Results indicated that children's level of reasoning, but not their gender constancy level, was related to gender-typed toy preferences. Children with more flexible norms, who could distinguish between moral and social norms, exhibited less gender-typed toy choices than children with rigid norms. Results are discussed in terms of the relation between cognitive aspects of gender typing and gender-typed toy preference.