Miracle-dz/UniFAR-FTUs huggingface dataset:
A Comparative Analysis of MEXT English Reading Textbooks and Japan’s National Center Test

Despite the influence of changing demographics in Japan, the National Center Test for University Entrance Exams continues to assert an ever increasing role in the process of university admissions. In preparation for this examination, the majority of senior high school students learn from textbooks approved by the Japanese Ministry of Education, Culture, Sports, Science, and Technology (MEXT). This study compares Section Six of the 2003-2007 and 2008-2009 National Center Test English reading examination with three widely used MEXT senior high school reading textbooks. By triangulating analyses of vocabulary, reading ease/grade level indices, reading skills, and comprehension item formats, thereby expanding the methodologies of previous research in this area, the study poses the question:To what degree do the text and comprehension tasks of MEXT textbooks compare with those which students will be expected to comprehend in the National Center Test reading examination? Updating the results of earlier studies, the descriptive and inferential statistics reveal that while the vocabulary levels of the textbook now appear to correspond more closely with recent versions of the examination, further alignment of readability, grade levels, and comprehension tasks is necessary if MEXT textbooks are to support the development of reading proficiency now required.
Views from the trenches: beginning teachers’ perceptions about their professional development

This paper explores the perceptions of primary and secondary school teachers who are currently in their induction phase (i.e. their first three years after graduation). It reports the views of approximately 300 teachers about their professional development. The methodological approach adopted was a questionnaire survey followed by in‐depth interviews of around 18 teachers. The results clearly indicate the type of support that beginning teachers in particular need at the start of their teaching career. It provides feedback as to what the education authorities and schools need to focus on in order to support beginning teachers. The essential link between pre‐service and continuing professional development is explored and identified as key to quality improvements at the school level.
Anger and shame elicited by discrimination: Moderating role of coping on action endorsements and salivary cortisol

Discrimination often elicits anger, and yet group members typically do not take actions to confront their situation. It may be that other emotions that run contrary to action-taking also arise (e.g., shame), limiting the active expression of anger. Indeed, Study 1 (N = 36) revealed that, using a failure feedback paradigm, women expressed greater shame when their failure was due to discrimination, compared to a lack of personal merit. In contrast to anger, self-reported shame was not associated with action-taking. In Study 2, women (N = 91) were emotionally primed to feel either anger or shame (vs. a no mood prime control), and the moderating influence of coping styles on the link between emotions, actions, and salivary cortisol levels following discrimination were assessed. Among women primed to feel anger, problem-focused coping predicted reduced self-reported shame, lower cortisol reactivity, and greater individualistic confrontational action endorsements. In contrast, priming shame increased cortisol reactivity, but diminished the relation between particular coping styles and their capacity to facilitate action. Findings are discussed in terms of the interactive influence of emotions and coping on responses to discrimination. Copyright © 2008 John Wiley & Sons, Ltd.
Primary refractory and early‐relapsed Hodgkin's lymphoma: strategies for therapeutic targeting based on the tumour microenvironment

Classical Hodgkin's lymphoma (cHL), a distinct disease entity with characteristic clinical and pathological features, accounts for approximately 10% of all malignant lymphomas. cHL can be considered a prototype model for how the tumour microenvironment influences cancer pathogenesis. Cellular components of the cHL microenvironment express molecules involved in cancer cell growth and survival, such as CD30L or CD40L. Moreover, several signal transduction pathways that are critical for the proliferation and survival of neoplastic Hodgkin Reed–Sternberg (HRS) cells, including NF‐κB, JAK–STAT, PI3K–AkT and ERK, are deregulated in cHL. Although most patients can be cured with modern treatment strategies, approximately a quarter experience either primary or secondary chemorefractoriness or disease relapse, thus requiring novel treatments. Preclinical and clinical evidence has elucidated a complex crosstalk between malignant HRS cells and the reactive cells of the microenvironment, which suggests that novel therapeutic approaches capable of targeting HRS cells along with reactive cells might overcome chemorefractoriness. In the near future, these novel therapies will also be tested in chemosensitive patients, to reduce the long‐term toxicity of chemo‐radiotherapy. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Dimension and exercise variance in assessment center scores: a large-scale evaluation of multitrait-multimethod studies.

This study addresses 3 questions regarding assessment center construct validity: (a) Are assessment center ratings best thought of as reflecting dimension constructs (dimension model), exercises (exercise model), or a combination? (b) To what extent do dimensions or exercises account for variance? (c) Which design characteristics increase dimension variance? To this end, a large set of multitrait-multimethod studies (N = 34) were analyzed, showing that assessment center ratings were best represented (i.e., in terms of fit and admissible solutions) by a model with correlated dimensions and exercises specified as correlated uniquenesses. In this model, dimension variance equals exercise variance. Significantly more dimension variance was found when fewer dimensions were used and when assessors were psychologists. Use of behavioral checklists, a lower dimension-exercise ratio, and similar exercises also increased dimension variance.
Modeling solder joint fatigue in combined environmental reliability tests with concurrent vibration and thermal cycling

In this paper we discuss the lifetime prediction for Pb-free soldered flip chip components under combined temperature cycling (TC) and vibration loading in terms of the failure mechanisms related to solder joint fatigue. We show the results of several experiments including failure analysis and comparison of lifetime models. For this purpose finite element analyses (FEA) of the thermal cycling and vibration load are carried out and the relevant damage parameters are extracted from these simulations. The results are used in the lifetime models to correlate experimental and predictive results. Shortcomings of the existing life prediction approaches are discussed and ways to improve lifetime prediction are suggested.
Our "increasingly mobile society"? The curious persistence of a false belief.

PURPOSE We call attention to the widespread belief that the United States is an "increasingly mobile society," despite the fact that overall mobility has generally declined since about 1950, and interstate mobility has generally not increased during the same period. We review and extend past research documenting these mobility trends. DESIGN AND METHODS We describe population-level mobility for people of all ages as well as for several adult age groups, using published data from the U.S. Current Population Survey. We use simple regression methods to estimate the size and significance of mobility trends. RESULTS Overall mobility rates have declined for individuals of all ages and among all age groups. The largest average annual declines occur for 20- to 29-year-olds, although the rate of decline for those aged 65 and older is also large. Interstate mobility has declined slightly or remained constant, except among adults between 45 and 64 years old. IMPLICATIONS Although there may be good reasons to worry about the future of family care provided to elderly individuals, increased geographic mobility does not appear to be one of them. We speculate on reasons why the false belief persists.
Antihypertensive Medications in End‐Stage Renal Disease

Hypertension is almost universal in end‐stage renal disease (ESRD) and contributes to the substantial cardiovascular (CV) morbidity and mortality observed in these patients. The management of blood pressure (BP) in ESRD is complicated by a number of factors, including missed dialysis treatments, intradialytic changes in BP, medication removal with dialysis, and poor correlation of BPs obtained in the dialysis unit with those at home and with CV outcomes. Control of extracellular volume with ultrafiltration and dietary sodium restriction represents the principal strategy to manage hypertension in ESRD, and antihypertensive medications are subsequently added if this strategy is inadequate. While reduction in BP with medication improves CV outcomes, few head‐to‐head clinical trials have been performed to firmly establish the superiority of one antihypertensive medication class over another. Therefore, individualization of therapy is necessary, and patient comorbidities must be considered. Angiotensin‐converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and beta‐blockers are reasonable first‐line agents for most patients. ACE inhibitors and ARBs exert cardioprotective effects that are independent of BP reduction. Medications that are removed with dialysis may be preferred in patients who are prone to develop intradialytic hypotension. Intradialytic hypertension can be managed with challenging the patient's dry weight and using nondialyzable medications. Within a class of antihypertensive medications, there may be large variability in drug removal with dialysis, which must be considered upon medication selection. Studies demonstrate that even thrice‐weekly dosing of medication after dialysis has robust BP‐lowering effects, which may be a useful regimen in nonadherent patients.
UK samples autism spectrum disorder : Evidence from Finnish and DSM-5 Investigating the cross-cultural validity of

The recent Diagnostic and Statistical Manual of Mental Disorders–Fifth Edition (DSM-5) reformulation of autism spectrum disorder has received empirical support from North American and UK samples. Autism spectrum disorder is an increasingly global diagnosis, and research is needed to discover how well it generalises beyond North America and the United Kingdom. We tested the applicability of the DSM-5 model to a sample of Finnish young people with autism spectrum disorder (n = 130) or the broader autism phenotype (n = 110). Confirmatory factor analysis tested the DSM-5 model in Finland and compared the fit of this model between Finnish and UK participants (autism spectrum disorder, n = 488; broader autism phenotype, n = 220). In both countries, autistic symptoms were measured using the Developmental, Diagnostic and Dimensional Interview. Replicating findings from English-speaking samples, the DSM-5 model fitted well in Finnish autism spectrum disorder participants, outperforming a Diagnostic and Statistical Manual of Mental Disorders–Fourth Edition (DSM-IV) model. The DSM-5 model fitted equally well in Finnish and UK autism spectrum disorder samples. Among broader autism phenotype participants, this model fitted well in the United Kingdom but poorly in Finland, suggesting that cross-cultural variability may be greatest for milder autistic characteristics. We encourage researchers with data from other cultures to emulate our methodological approach, to map any cultural variability in the manifestation of autism spectrum disorder and the broader autism phenotype. This would be especially valuable given the ongoing revision of the International Classification of Diseases–11th Edition, the most global of the diagnostic manuals.
The Relationship between Visual-Motor Integration and Articulation Disorders in Preschool Children

The goal of this study was to assess the prevalence of articulation disorders and its relationship with visual-motor integration (VMI) in preschool children. An additional goal was to check for the effect of the child's gender on both articulation disorders and visual-motor integration. The sample consisted of 286 preschool children ages 3 to 6 years and attending preschool institutions in Canton Sarajevo, Bosnia and Herzegovina. We measured visual-motor integration skills by using the Beery VMI- Test of Visual Motor Integration (6th ed.) Short Form and language skills by using the Bosnian test for the assessment of articulation disorders. The prevalence of articulation disorders in the sample was 34.3%. There was a significant difference in VMI between children with and without articulation disorders. The effect of gender was significant for both articulation disorder and VMI, with boys having a higher risk to have articulation disorder and VMI deficit. There is a high prevalence of articulation disorders and VMI deficits in preschool children. Given this high prevalence of visual-motor and speech disorders, preschool institutions should provide early speech and fine-motor screening of the children and subsequent speech and occupational therapy.
A more active treatment has profound effects on the health status of rheumatoid arthritis (RA) patients: results from a population-based RA register in Malmö, Sweden, 1997–2005

Objective: Population-based studies on the trends and effects of modern antirheumatic treatment are scarce. The aim of this study was to examine trends in treatment, health-related quality of life (HRQL), and disease outcome in a population-based register of patients with rheumatoid arthritis (RA) in Malmö, Sweden. Methods: A continuously updated population-based RA register was established in the city of Malmö, southern Sweden, in 1997. Self-completed postal questionnaires issued in 1997, 2002, and 2005 were used to collect information on demographics, medication, and health status. Cross-sectional comparisons were made between data from 1997, 2002, and 2005. Results: Between 1997 and 2005, the proportion of patients treated with any disease-modifying anti-rheumatic drug (DMARD) including biologics increased substantially (from 52% to 87%), as well as the proportion treated with methotrexate (from 23% to 52%) and biologics (almost exclusively tumour necrosis factor inhibitors) (from 0% to 20%). Twelve per cent of RA patients received biologics 5 years from disease onset in 2005. In parallel with changes in treatment, mean Health Assessment Questionnaire (HAQ) scores (1.19 vs. 0.89) and all Short Form 36 (SF-36) subscales improved from 1997 to 2005 (non-overlapping confidence intervals). Conclusion: Between 1997 and 2005, there was a substantial increase in the use of DMARDs, which was accompanied by improved mean HAQ and SF-36 scores in cross-sectional comparisons. These results support the concept that more intensive treatment with DMARDs and biologics can have profound effects on the overall health status in RA patients at the population level.
An $X$ -Band Half-Watt CMOS Power Amplifier Using Interweaved Parallel Combining Transformer

An <inline-formula> <tex-math notation="LaTeX">$X$ </tex-math></inline-formula>-band half-watt fully integrated power amplifier (PA) using standard 0.18-<inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> 1P6M CMOS technology is presented in this letter. Utilizing an interweaved three-primary parallel combining transformer, the CMOS PA delivers 27.1 dBm of measured saturation output power (<inline-formula> <tex-math notation="LaTeX">$P_{\mathbf {sat}}$ </tex-math></inline-formula>) with 22.7% of power-added efficiency at 9 GHz from a 3.3-V power supply. The measured output 1-dB gain compression point (<italic>OP</italic><sub>1 dB</sub>) is 24.2 dBm and the gain performance is 11.2 dB at 9 GHz. The chip size is <inline-formula> <tex-math notation="LaTeX">$1.045 \times 0.84$ </tex-math></inline-formula> mm<inline-formula> <tex-math notation="LaTeX">$^{{\mathbf {2}}}$ </tex-math></inline-formula>. To the best of our knowledge, the PA is the first half-watt CMOS PA with excellent power density at the <inline-formula> <tex-math notation="LaTeX">$X$ </tex-math></inline-formula>-band.
Developing a New Approach to the Assessment of Project Work

ABSTRACT Despite the inevitable constraints inherent in effecting a major change of policy and practice, a new approach to the assessment of undergraduate honours research projects in two science‐based teaching units was achieved through an evolutionary active research‐based process. The implications of a transition from a subjective assessment of honours projects to a more objective, criterion‐referenced strategy were investigated through implementation and feedback. A pilot study was undertaken in which project assessors were asked to use a criterion‐referenced scheme in parallel with the existing scheme. Statistical analyses of data obtained using both the ‘old’ and ‘new’ schemes confirmed the reliability of the new criterion‐referenced assessment strategy. In addition, the new scheme offered a number of important advantages over the old system: (1) increased objectivity through reference to a number of clearly defined explicit criteria, (2) opportunity for the provision of valuable feedback to the stu.
Growth of massive black holes by super-Eddington accretion

Narrow-Line Seyfert 1 galaxies (NLS1s) and Narrow-Line quasars (NLQs) seem to amount to ∼ 10–30% of active galactic nuclei (AGNs) in the local universe. Together with their average accretion rate, we argue that a black hole (BH) growth by factor of 8–800 happens in these super-Eddington accretion phase of AGNs. Moreover, there is a possible, systematic underestimation of accretion rates (in the Eddington unit) due to an overestimation of BH mass by massive accretion discs for super-Eddington objects. If it is true, the factor of BH growth above may be larger by order(s) of magnitude. In contrast, the growth factor expected in sub-Eddington phase is only ∼ 2. Therefore, the cosmic BH growth by accretion is likely dominated by super-Eddington phase, rather than sub-Eddington phase which is the majority among AGNs. This analysis is based on the fraction and the average accretion rate of NLS1s and NLQs obtained for $z \lesssim 0.5$. If those numbers are larger at higher redshift (where BHs were probably less grown), super-Eddington accretion would be even more important in the context of cosmic BH growth history.
Heart rate recovery and survival in patients undergoing stereotactic body radiotherapy for treatment of early-stage lung cancer.

Objectives Up to 25% of patients with stage I non-small cell lung cancer (NSCLC) are considered high-risk for surgery, due to severe medical comorbidity and/or poor pulmonary reserve. Many of these patients are treated with stereotactic body radiotherapy (SBRT). Prognosis in this subgroup of patients is difficult to determine. We investigated the association of impaired heart rate recovery (HRR) with survival in patients who received SBRT for treatment of early-stage lung cancer. Methods We collected data from consecutive patients who, between October 2009 and December 2012, received SBRT for treatment of lung cancer at the Cleveland Clinic, and had 6-minute walk test (6MWT) followed by HRR evaluation performed within six months of initiation of treatment. Impaired HRR was defined as a ≤ 12 beat decrease within the first minute following the 6MWT. Survival analyses were performed using Kaplan-Meier estimates and Cox proportional hazard ratios. Results Forty nine patients who received SBRT for treatment of early-stage lung cancer had HRR data available. Thirty two (65%) patients had impaired HRR following the 6MWT. In univariable and multivariable Cox regression analyses, impaired HRR was associated with poorer survival (HR: 11.0, 95% CI: 1.42 - 84.4, p = 0.004, and HR: 15.8, 95% CI: 1.96 - 128.0, p = 0.010, respectively). The 2-year overall survival rates were 52.6% for those with impaired HRR, and 94.1% for those with normal HRR. Conclusion Impaired HRR was associated with poorer survival in patients who received SBRT for treatment of early-stage lung cancer. HRR following the 6MWT can be one of the factors considered in patient selection for treatment with SBRT, along with other medical comorbidities.
Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals.

BACKGROUND Large outbreaks of diarrhea caused by a newly recognized strain of Clostridium difficile occurred in four hospitals located in different parts of the United States between 1989 and 1992. Since frequent use of clindamycin was associated with the outbreak in one of the hospitals, we examined the resistance genes of the epidemic-strain isolates and studied the role of clindamycin use in these outbreaks. METHODS Case-control studies were performed at three of the four hospitals to assess the relation of the use of clindamycin to C. difficile-associated diarrhea. All isolates of the epidemic strain and representative isolates of other strains identified during each outbreak were tested for susceptibility to clindamycin. Chromosomal DNA from these representative isolates was also analyzed by dot blot hybridization and amplification with the polymerase chain reaction (PCR) with the use of probes and primers from a previously described determinant of erythromycin resistance - the erythromycin ribosomal methylase B (ermB) gene - found in C. perfringens and C. difficile. RESULTS In a stratified analysis of the case-control studies with pooling of the results according to the Mantel-Haenszel method, we found that the use of clindamycin was significantly increased among patients with diarrhea due to the epidemic strain of C. difficile, as compared with patients whose diarrhea was due to nonepidemic strains (pooled odds ratio, 4.35; 95 percent confidence interval, 2.02 to 9.38; P<0.001). Exposure to other types of antibiotics or hospitalization in a surgical ward was not significantly associated with the risk of C. difficile-associated diarrhea due to the epidemic strain. All epidemic-strain isolates were highly resistant to clindamycin (minimal inhibitory concentration, >256 microg per milliliter). DNA hybridization and PCR analysis showed that all these isolates had an ermB gene, which encodes a 23S ribosomal RNA methylase that mediates resistance to macrolide, lincosamide, and streptogramin antibiotics. Only 15 percent of the nonepidemic strains were resistant to clindamycin. CONCLUSIONS A strain of C. difficile that is highly resistant to clindamycin was responsible for large outbreaks of diarrhea in four hospitals in different states. The use of clindamycin is a specific risk factor for diarrhea due to this strain. Resistance to clindamycin further increases the risk of C. difficile-associated diarrhea, an established complication of antimicrobial use.