Miracle-dz/UniFAR-FTUs huggingface dataset:
Detection of Francisella tularensis in clinical specimens by use of polymerase chain reaction.

Culture-proven acute brucellosis was diagnosed in both the paintercourse, sexual transmission is the most likely route of infection. Our observations, in accordance with previous published retient and his girlfriend. Although the young man had a history of travel to Syria and recalled the consumption of unpasteurized dairy ports concerning B. melitensis, support the theory that person-toproducts, his girlfriend had not been to the Middle East and denied person transmission is possible for B. abortus. any ingestion of imported cheese or milk. In Austria as well the rest of the European Community, cattle, goats, and sheep are free F. Thalhammer, G. Eberl, and U. Kopetzki-Kogler from infection with B. abortus. Dairy products are produced almost Department of Internal Medicine I, Division of Infectious Diseases, exclusively from pasteurized milk and are subjected to routine University of Vienna, and Department of Internal Medicine IV, quality and microbiological testing. Wilhelminen Spital der Gemeinde Wien, Vienna, Austria Brucellosis in humans occurs primarily as a result of occupational exposure; close contact with infected animals is the main References route of infection. Other important means of transmission are the 1. Goossens H, Marcelis L, Dekeyser P, Butzler JP. Brucella melitensis: peringestion of contaminated dairy products, inhalation of infectious son-to-person transmission? Lancet 1983;321:773. aerosols, blood transfusion, or exposure to Brucella in microbio2. StantıB c-Pavlinic M, Ćec V, Mehle J. Brucellosis in spouses and the possibillogical laboratories. Possible sexual transmission has been docuity of interhuman infection. Infection 1983;11:313–4. mented for B. melitensis [1–4]; B. melitensis was isolated from 3. Lindberg J, Larsson P. Transmission of Brucella melitensis. Lancet 1991; the sperm of one patient [5]. 337:848–9. To our knowledge, we describe the first case of possible sexual 4. Mantur BG, Mangalgi SS, Mulimani M. Brucella melitensis—a sexually transmission of B. abortus in humans. Although the young man transmissible agent? [letter] Lancet 1996;347:1763. contracted brucellosis via ingestion of contaminated food in the 5. Vandercam B, Zech F, de Cooman S, Bughin C, Gigi J, Wauters G. Isolation Middle East, his girlfriend had no risk factors predisposing her to of Brucella melitensis from human sperm [letter]. Eur J Clin Microbiol Infect Dis 1990;9:303. B. abortus infection. Given that the couple had unprotected sexual
American and South Korean Engineering Students’ Communication Motives and Their Student–Instructor Communication Satisfaction

The purpose of this study was twofold. The first purpose was to compare American and South Korean engineering students’ motives (i.e., relational, functional, excuse-making, participatory, and sycophantic) for communicating with their instructors and their student–instructor communication satisfaction. The second purpose was to examine the extent to which both American and South Korean engineering students’ motives for communicating with their instructors are related to their student–instructor communication satisfaction. Undergraduate students (N = 168) recruited from public universities in the United States and South Korea participated in this study. The results of a multivariate analysis of variance (MANOVA), an independent sample t-tests, a series of zero-order Pearson correlational analyses, and Fisher z-tests revealed significant cultural differences and that the relationship between students’ communication motives and their student–instructor communication satisfaction largely are consistent between the two cultures.
Beyond Independence: Probabilistic Models for Query Approximation on Binary Transaction Data

We investigate the problem of generating fast approximate answers to queries posed to large sparse binary data sets. We focus in particular on probabilistic model-based approaches to this problem and develop a number of techniques that are significantly more accurate than a baseline independence model. In particular, we introduce two techniques for building probabilistic models from frequent itemsets: the itemset maximum entropy model and the itemset inclusion-exclusion model. In the maximum entropy model, we treat itemsets as constraints on the distribution of the query variables and use the maximum entropy principle to build a joint probability model for the query attributes online. In the inclusion-exclusion model, itemsets and their frequencies are stored in a data structure, called an ADtree, that supports an efficient implementation of the inclusion-exclusion principle in order to answer the query. We empirically compare these two itemset-based models to direct querying of the original data, querying of samples of the original data, as well as other probabilistic models such as the independence model, the Chow-Liu tree model, and the Bernoulli mixture model. These models are able to handle high-dimensionality (hundreds or thousands of attributes), whereas most other work on this topic has focused on relatively low-dimensional OLAP problems. Experimental results on both simulated and real-world transaction data sets illustrate various fundamental trade offs between approximation error, model complexity, and the online time required to compute a query answer.
Prevalence of anorexia nervosa and bulimia in three student populations

A confidential questionnaire, covering the DSM-III criteria for anorexia nervosa and bulimia, was administered to three samples of students, totalling 1060 individuals, at two colleges and a secondary school. Although none of the male respondents met DSM-III criteria for either disorder, 1.0% to 4.2% of women met DSM-III criteria for a history of anorexia nervosa (with or without a history of bulimia), and an additional 6.5% to 18.6% met DSM-III criteria for a history of bulimia alone. Even when allowance is made for the number of nonrespondents, possible falsepositive questionnaire responses, and the limitations of the DSM-III criteria themselves, the prevalence rates appear substantial. Taking into account the mean ages of various samples, our results agree closely with two previous studies that each examined a single sample of students. These results augment the growing evidence that the eating disorders represent a serious public health problem.
Consumption Emotions, Experience Quality and Satisfaction

Abstract Previous research has demonstrated that attribute based evaluations are significant determinants of satisfaction: direct and indirect effects through cognitive evaluation induced emotions. This study argues that in a multiple-encounter service environment like tourism the experience elicited emotions are antecedent to the final cognitive evaluation of the entire consumption episode. Both affective and cognitive responses exercise an almost independent impact on overall satisfaction conceptualized according to Oliver's (1997) multi-domain approach. Considerable differences in the structure of cognitive effects on satisfaction are demonstrated for complaining and non-complaining consumers.
RECONSTITUTION OF ANTIPHAGE ANTIBODIES FROM L AND H POLYPEPTIDE CHAINS AND THE FORMATION OF INTERSPECIES MOLECULAR HYBRIDS

Reconstitution of phage-neutralizing activity was observed after admixture of separated L and H polypeptide chains of purified antibodies obtained from single sheep or guinea pigs and directed against f1 and f2 phages. Hybrid mixtures of complementary chains of antiphage antibodies and γ-globulins of the same animal showed less activity than the homologous mixtures of chains from antibodies of the same specificity. 7S interspecies molecular hybrids could be formed between L or H chains of sheep γ-globulins and the complementary chains of guinea pig γ-globulins. In contrast to the results obtained within a single animal species, mixtures of L or H chains of antiphage antibodies from one species with the complementary chains of antibodies to the same phage from the other species showed slight or negligible potentiation of neutralizing activity.
Understanding the H2/H i ratio in galaxies

We revisit the mass ratio R between molecular hydrogen (H2) and atomic hydrogen (HI) in different galaxies from a phenomenological and theoretical viewpoint. First, the local H2 mass function (MF) is estimated from the local CO luminosity function (LF) of the FCRAO Extragalactic CO-Survey, adopting a variable CO-to-H2 conversion fitted to nearby observations. This implies an average H2-density Omega(H2)=(6.9±2.7)x10^(-5)/h and Omega(H2)/Omega(HI)=0.26±0.11 the local Universe. Secondly, we investigate the correlations between R and global galaxy properties in a sample of 245 local galaxies. Based on these correlations we introduce four phenomenological models for R, which we apply to estimate H2 masses for each HI galaxy in the HIPASS catalogue. The resulting H2-MFs (one for each model for R) are compared to the reference H2-MF derived from the CO LF, thus allowing us to determine the Bayesian evidence of each model and to identify a clear best model, in which, for spiral galaxies, R negatively correlates with both galaxy Hubble type and total gas mass. Thirdly, we derive a theoretical model for R for regular galaxies based on an expression for their axially symmetric pressure profile dictating the degree of molecularization. This model is quantitatively similar to the best phenomenological one at redshift z=0, and hence represents a consistent generalization while providing a physical explanation for the dependence of R on global galaxy properties. Applying the best phenomenological model for R to the HIPASS sample, we derive the first integral cold gas MF(HI+H2+helium) of the local universe.
Entrance Correlates of University Satisfaction

Students within an institution differ in their degree of expressed satisfaction with their college experiences. Some students, both before and after graduation, say they are well-satisfied with their University, while other students in the same institution express dissatisfaction. Student satisfaction is only one of several possible criteria as to how well a University functions, but it is a criterion to which the University must continuously respond. What determines how well satisfied students are with their college? How much can such satisfaction be influenced by the college, and what can the college do to alter student satisfaction? To what extent is the satisfaction a student will experience with his college predetermined even before he matriculates and to what extent is such satisfaction influenced by the progress and success of the student in the University?
miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome

In humans, the most common genomic disorder is a hemizygous deletion of a 1.5–3 Mb region of chromosome 22q11.2. The resultant 22q11.2 deletion syndrome (22q11.2DS) can affect multiple organ systems, and most notably includes cardiac, craniofacial, and neurodevelopmental defects. Individuals with 22q11.2DS have a 20–25-fold risk of developing schizophrenia compared to individuals from the general population, making 22q11.2DS the strongest known molecular genetic risk factor for schizophrenia. Although the deleted region includes DGCR8, a gene coding for a miRNA processing protein, the exact mechanism by which this deletion increases risk is unknown. Importantly, several lines of evidence suggest that miRNAs may modulate risk for schizophrenia in other, non-22q11.2DS populations. Here we present a theory which mechanistically explains the link between 22q11.2DS, miRNAs, and schizophrenia risk. We outline the testable predictions generated by this theory and present preliminary data in support of our model. Further experimental validation of this model could provide important insights into the etiology of both 22q11.2DS and more common forms of schizophrenia.
Role of β-Defensin-1 Polymorphisms in Mother-to-Child Transmission of HIV-1

Background and Objectives:Mother-to-child transmission (MTCT) of HIV-1, the main source of pediatric AIDS, is multifactorial. Defensins provide microbial barriers and function as effectors of innate immunity. This study investigated the relationship between genetic variants of β-defensin-1 gene and MTCT of HIV-1. Patients and Methods:Three hundred children, 118 HIV-1 infected and 182 HIV-1 uninfected, born to HIV-1-infected mothers who had not undergone antiretroviral therapy during pregnancy, and 84 HIV-1-infected mothers were analyzed. The single nucleotide polymorphisms -44C/G (rs1800972) and -52G/A (rs1799946) were genotyped by TaqMan allelic discrimination assay and sequencing. Statistical analyses were performed using SNPStats and Bonferroni correction for multiple tests. Results:In children, the -52GG genotype and the -44G/-52G haplotype had a protective role against HIV-1 infection [odds ratio (OR) = 0.52, 95% confidence interval (CI) 0.31 to 0.86, P = 0.03 and OR = 0.50, 95% CI 0.31 to 0.83, P = 0.014, respectively]. In mothers, the -52GG genotype and the -44G/-52G haplotype were associated with low levels of HIV-1 plasma viremia (<1000 copies/mL) and a lower risk of maternal HIV-1 transmission (OR = 0.14, 95% CI 0.03 to 0.67, P = 0.009 and OR = 0.23, 95% CI 0.08 to 0.66, P = 0.012, respectively). Conclusions:These results demonstrate a significant relationship between genetic variants of β-defensin-1 gene, viral load, and MTCT of HIV-1, thus supporting a critical role of innate immunity in pediatric HIV-1 infection.
Cognitive behavioral therapy for adolescent depression: implications for Asian immigrants in the United States of America

Many interventions are available for treating adolescent depression. This paper attempts to present a summary of cognitive behavioral therapies/techniques that might be useful for treating depression in Asian immigrant adolescents. Articles were selected by conducting a literature search on Psyc-Info. Prevalence, symptoms and measures of adolescent depression are discussed. Summary of popular therapies like PASCET, CWD-A, Beck's CBT are provided. A rationale for the use of these with Asian immigrants is hypothesized. There is no empirical evidence for the efficacy of CBT with this population. A need to validate the use of CBT with this population is asserted.
Functional Evidence of Multidrug Resistance Transporters (MDR) in Rodent Olfactory Epithelium

Background P-glycoprotein (Pgp) and multidrug resistance-associated protein (MRP1) are membrane transporter proteins which function as efflux pumps at cell membranes and are considered to exert a protective function against the entry of xenobiotics. While evidence for Pgp and MRP transporter activity is reported for olfactory tissue, their possible interaction and participation in the olfactory response has not been investigated. Principal Findings Functional activity of putative MDR transporters was assessed by means of the fluorometric calcein acetoxymethyl ester (calcein-AM) accumulation assay on acute rat and mouse olfactory tissue slices. Calcein-AM uptake was measured as fluorescence intensity changes in the presence of Pgp or MRP specific inhibitors. Epifluorescence microscopy measured time course analysis in the olfactory epithelium revealed significant inhibitor-dependent calcein uptake in the presence of each of the selected inhibitors. Furthermore, intracellular calcein accumulation in olfactory receptor neurons was also significantly increased in the presence of either one of the Pgp or MRP inhibitors. The presence of Pgp or MRP1 encoding genes in the olfactory mucosa of rat and mouse was confirmed by RT-PCR with appropriate pairs of species-specific primers. Both transporters were expressed in both newborn and adult olfactory mucosa of both species. To assess a possible involvement of MDR transporters in the olfactory response, we examined the electrophysiological response to odorants in the presence of the selected MDR inhibitors by recording electroolfactograms (EOG). In both animal species, MRPs inhibitors induced a marked reduction of the EOG magnitude, while Pgp inhibitors had only a minor or no measurable effect. Conclusions The findings suggest that both Pgp and MRP transporters are functional in the olfactory mucosa and in olfactory receptor neurons. Pgp and MRPs may be cellular constituents of olfactory receptor neurons and represent potential mechanisms for modulation of the olfactory response.
Hepatic artery injection of Yttrium-90-lipiodol: biodistribution in rats with hepatoma.

UNLABELLED In this study, we analyzed the biodistribution of 90Y-lipiodol in rats with liver tumors (hepatoma) following hepatic arterial injection. METHODS Sixteen male Sprague-Dawley rats with liver tumors were killed at 1, 24, 48 and 72 hr (four rats at each time) after injection of approximately 0.1 mCi 90Y-lipiodol through the hepatic artery, respectively. Samples of tumor, liver, spleen, skeletal muscle, lung, kidney, bone, whole blood and testis were obtained and counted to calculate the tissue concentrations (%ID/g). RESULTS We found that the radioactivity in the liver tumor was high at 1 and 24 hr and then declined slowly. The biological half-time was 84.1 hr. The radioactivity in normal liver tissue was also high at 1 hr but was significantly lower than that in the tumor. The biological half-time was 38.5 hr. The ratio of tissue concentration between liver tumor and normal liver tissue (T/N ratio) was 3.03 at 1 hr and rose to 6.45 at 72 hr. The radioactivity in the lung was almost as high as in normal liver tissue at 1 hr and declined rapidly with a biological half-time of 25.6 hr. The activity levels of the kidney were moderate at 1 hr and remained at almost the same level throughout the study. A moderate concentration of radioactivity in bone was noted within the first 24 hr. The concentration, however, rose over the ensuing time. The concentration of radioactivity in skeletal muscle, spleen, testis and whole blood was quite low. CONCLUSION Following hepatic arterial injection of 90Y-lipiodol, tracer uptake in liver tumor was high and tumor retention was lengthy. Consequently, large radiation doses could be delivered to the tumor. We suggest that 90Y-lipiodol is a potential agent in the treatment of liver malignancy.
SubtiList: the reference database for the Bacillus subtilis genome

SubtiList is the reference database dedicated to the genome of Bacillus subtilis 168, the paradigm of Gram-positive endospore-forming bacteria. Developed in the framework of the B.subtilis genome project, SubtiList provides a curated dataset of DNA and protein sequences, combined with the relevant annotations and functional assignments. Information about gene functions and products is continuously updated by linking relevant bibliographic references. Recently, sequence corrections arising from both systematic verifications and submissions by individual scientists were included in the reference genome sequence. SubtiList is based on a generic relational data schema and a World Wide Web interface developed for the handling of bacterial genomes, called GenoList. The World Wide Web interface was designed to allow users to easily browse through genome data and retrieve information according to common biological queries. SubtiList also provides more elaborate tools, such as pattern searching, which are tightly connected to the overall browsing system. SubtiList is accessible at http://genolist.pasteur. fr/SubtiList/. Similar bacterial databases are accessible at http://genolist.pasteur. fr/.
“The Real Work is What They Do Together”*: Peer Support and Birth Parent Change

This article examines a peer support intervention with birth parents in the child welfare system. Literature on the emotional change process for child welfare-involved parents, peer-support intervention-outcome studies in child welfare, and findings on peer support in related fields is reviewed. The Mendocino County Family Services Center (MCFSC) model is described, and findings from an exploratory study are presented and discussed. This model engages parents in a sequence of services based on developmental stages. The study used focus groups, interviews, and observation to understand the key components of the MCFSC peer support intervention, and the experience of birth-parent participants with respect to their personal change process. Further research into this model and other interventions that promote birth-parent change in child welfare is warranted.
Cognitive and social simulation of criminal behaviour: the intermittent explosive disorder case

Criminal behaviour often involves a combination of physical, mental, social and environmental (multi-)agent aspects, such as neurological deviations, hormones, arousal, (non)empathy, targets and social control. This paper contributes a dynamical agent-based approach for analysis and simulation of criminal behaviour, covering the above aspects, illustrated for the case of an Intermittent Explosive Disorder. It involves dynamically generated desires and beliefs in opportunities within the social environment, both based on literature on criminal behaviour.
Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up A. Okines, M. Verheij, W. Allum, D. Cunningham & A. Cervantes On behalf of the ESMO Guidelines Working Group* GI Clinical Trials Unit, Royal Marsden Hospital, Sutton, UK; Department of Radiation Oncology and Division of Cellular Biochemistry, The Netherlands Cancer Institute—Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; Department of Surgery, Royal Marsden Hospital, London; Department of Medicine, Royal Marsden Hospital, Sutton, UK; Department of Hematology and Medical Oncology, INCLIVA, University of Valencia, Valencia, Spain
Hetero-plane beam synthesis using 60 GHz band 3-D phased array antenna module

A 60GHz band 3-dimensional (3-D) phased array antenna module has been fabricated and hetero-plane beam synthesis is demonstrated. Two separated 2×2 end-fire dipole array antennas in different (z-y and z-x) planes are configured in a multi-stacked substrate module. For x-direction, z-y plane array antenna is used and for y-direction, z-x plane array antenna is used. In order to achieve higher antenna gain at intermediate region between x and y directions, hetero-plane beam synthesis is employed using two array antennas in different (z-y and z-x) planes. Measured radiation patterns are in agreement with simulated radiation patterns and wider 10 dBi beam coverage area of 150° in azimuth and 60° in elevation is obtained. The results show the effectiveness of proposed hetero-plane beam synthesis.
Parents as Informants of Their Child's Vocal and Early Language Development.

Continuity in vocalization and language development was examined in the longitudinal study of 94 children. Parents observed their infant's vocal development with the help of a checklist during the first year of life and reported their lexical development by using the MacArthur Communicative Development Inventories (the CDIs) at the ages of 14 and 18 months. The Reynell Developmental Language Scales (the RDLS) were administered to the children in a laboratory setting at 18 months. The vocalization checklist revealed milestones of sound production which parents reported reliably and which were significantly related to the child's later language development. The continuity in vocal and language development was supported by a subgroup analysis, which showed that the early vocalizers had comprehended and produced significantly more words and suffixes than had the late vocalizers during the second year. The results also provided support to the concurrent and predictive validity of the CDIs. Significant correlat.