Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Carbohydrase Supplement on Lactation Performance of Primiparous Sows Fed Corn-Soybean Meal Based Lactation Diet

The experiment was conducted to test the hypothesis that supplementing diets of lactating first parity sows with a mixture of carbohydrases (CS) improves lactation performance and second parity reproductive performance. The CS used in this study contained 7 units/g of α-1,6-galactosidase, 22 units/g of β-1,4-mannanase, β-1,4-mannosidase and trace amounts of other enzymes. Twenty primiparous sows (Newsham Hybrid) were allotted to either the control group (no CS supplement) or the CS group (0.1% CS supplement) and fed the experimental diets during 21 d lactation period. Sows and nursing pigs were weighed at birth and weekly until weaning. Days of weaning-to-estrus were recorded. Sows had free access to feed and water. Feed intake of sows was measured daily. During the second parity gestation and lactation, all the sows were fed the same gestation and lactation diets and their reproductive performance was measured. During the second parity, there were 14 sows (7 sows per group) remained productive. For the first lactation, maternal body weight loss of the CS group was smaller (p<0.05) than that of the control group. There was no difference in litter weight gain between two groups. Voluntary feed intake of sows did not differ between the two groups. Days of weaning-to-estrus of the CS group were smaller (p<0.05) than those of the control group. In the second parity, there was no difference in the reproductive performance between the two groups. In conclusion, supplementing CS in the diet of lactating sows during the first parity decreased body weight loss and days of weaning-to-estrus of sows. However, these effects of the CS supplementation in the first parity were not successfully carried over to the second parity. (Asian-Aust. J. Anim. Sci. 2004. Vol 17, No. 4 : 533-537)
Cytomegalovirus glycoprotein B genotyping in ocular fluids and blood of AIDS patients with cytomegalovirus retinitis.

PURPOSE To determine the frequency of cytomegalovirus glycoprotein B (gB) genotypes in clinical samples of ocular fluids of patients with acquired immune deficiency syndrome (AIDS) who have cytomegalovirus retinitis and to compare these with the cytomegalovirus gB genotype in paired peripheral blood leukocytes. METHODS Glycoprotein B genotypes of cytomegalovirus genomic DNA were determined in 29 ocular and 9 paired blood samples of 27 patients, by polymerase chain reaction amplification followed by restriction fragment length polymorphism analysis. RESULTS In the 29 ocular samples, 30 gB genotypes were determined: Glycoprotein B1 was found in 8 samples (27%), gB2 in 9 samples (30%), gB3 in 6 samples (20%), and gB4 in 3 samples (10%). In one sample, a mixed genotype was observed. In addition to these previously characterized gB genotypes, a new gB variant was observed in the ocular fluid of four patients. Partial sequence analysis revealed that this new gB genotype is closely related to gB3, and it was therefore named gB3'. In the blood samples, only gB1, gB2, and gB3 genotypes were observed. In the nine paired samples of ocular fluid and blood, four showed a difference in gB genotype between these compartments. CONCLUSIONS The distribution of cytomegalovirus glycoprotein B genotypes gB1-gB4 in ocular fluids of patients with AIDS who have cytomegalovirus retinitis was determined in this study. The predominance of gB2, as described by others, was not confirmed. The glycoprotein B genotype in the eye can be different from the genotype found in the blood of the same patient. A new gB variant, gB3', was found in the ocular samples of 4 of 27 patients, but not in the blood samples tested.
Identification of Foot Pathologies Based on Plantar Pressure Asymmetry

Foot pathologies can negatively influence foot function, consequently impairing gait during daily activity, and severely impacting an individual’s quality of life. These pathologies are often painful and correspond with high or abnormal plantar pressure, which can result in asymmetry in the pressure distribution between the two feet. There is currently no general consensus on the presence of asymmetry in able-bodied gait, and plantar pressure analysis during gait is in dire need of a standardized method to quantify asymmetry. This paper investigates the use of plantar pressure asymmetry for pathological gait diagnosis. The results of this study involving plantar pressure analysis in fifty one participants (31 healthy and 20 with foot pathologies) support the presence of plantar pressure asymmetry in normal gait. A higher level of asymmetry was detected at the majority of the regions in the feet of the pathological population, including statistically significant differences in the plantar pressure asymmetry in two regions of the foot, metatarsophalangeal joint 3 (MPJ3) and the lateral heel. Quantification of plantar pressure asymmetry may prove to be useful for the identification and diagnosis of various foot pathologies.
Conditionally Immortalized Clonal Cell Lines from the Mouse Olfactory Placode Differentiate into Olfactory Receptor Neurons

To test extracellular signals that direct the development of the olfactory system, we have generated clonal temperature-sensitive cell lines that represent distinct cellular lineages derived from the E10 mouse olfactory placode. Two of these lines, OP6 and OP27, express (at the permissive temperature), a transcriptional profile representing intermediate-late developmental stages in the olfactory receptor neuron (ORN) lineage. At the nonpermissive temperature, both OP6 and OP27 cells can be induced by all-trans retinoic acid to differentiate into a population of mature bipolar ORN-like cells. In response to retinoic acid, differentiated OP6 and OP27 down-regulate neuron-specific transcription factors required for early stages of neuronal differentiation, and shift active components of the neurotrophin signaling cascade (Trk receptors) into a kinase inactive state. When morphologically mature, OP6 and OP27 express the mature ORN chemosensory signaling components, olfactory G-protein (G(olf)), Type III adenylate cyclase (ACIII), OCNC1, and the olfactory marker protein (OMP). OP27 expresses one odorant receptor, OR 27-3. OP6 expresses two very closely related receptors, OR 6-13 and OR 6-8. Voltage-gated sodium and potassium channels resembling those recorded from primary cultures of ORNs can also be recorded from a subset of differentiated OP6 cells.
Nurses' lived experience of spirituality in relation to helping patients cope with loss in situations of chronic and terminal illness

This qualitative study explores spiritual issues in relation to coping with loss in situations of chronic and terminal illness. An Heideggerian hermeneutic phenomenological approach was chosen as the most appropriate methodology for exploring nurses’ lived experience of utilising spirituality as a means of helping patients cope with loss. My prior knowledge both brought me to the subject of study and influenced my interpretation of data. To ensure transparency of method this prior knowledge is outlined in my fore-structure of understanding. A purposive sample of 12 registered nurses, 5 from hospice, 4 from community practice and 3 from a nursing home setting participated in semi-structured interviews. A stepped process of analysis of interview texts produced overarching themes which are illustrated with excerpts that collectively produce a ‘thick enough description’ intended to facilitate understanding of my interpretation of data by those who chose to read this study. Findings were illuminated by drawing on existing theoretical knowledge and concepts. My research diary and notes at interview constituted a research journal that recorded how my knowledge and understanding developed through my reflection on, and reflexive response to interview data. In this way my research journal was used to illuminate the research process. There are an increasing number of studies that consider spirituality in healthcare and how patients’ spiritual needs can be recognised and fulfilled. However, this study provides a different perspective, in particular, examples of how nurses’ development as persons may render them not only a spiritual resource in themselves, but also, contribute to how they become proficient in spiritual care in situations of loss. There were four overriding ways in which the development of this aptitude was evident. Firstly, belief provided them with a means of coming to an understanding of why things happen and so helped them accommodate repeated exposure to patients’ grief. Secondly, being a spiritual carer involved establishing a relationship with patients through ‘connected’ communication. Thirdly, becoming proficient in spiritual care was reflected by an increasing maturity in engaging with patients’ real life and death issues, which was sustained by taking ‘time out’ to reconnect with the self. Finally, belonging to a team whose culture reflected a spirit of reciprocal support was crucial when patient care was emotionally demanding.
Structural Brain Changes in Aging: Courses, Causes and Cognitive Consequences

The structure of the brain is constantly changing from birth throughout the lifetime, meaning that normal aging, free from dementia, is associated with structural brain changes. This paper reviews recent evidence from magnetic resonance imaging (MRI) studies about age-related changes in the brain. The main conclusions are that (1) the brain shrinks in volume and the ventricular system expands in healthy aging. However, the pattern of changes is highly heterogeneous, with the largest changes seen in the frontal and temporal cortex, and in the putamen, thalamus, and accumbens. With modern approaches to analysis of MRI data, changes in cortical thickness and subcortical volume can be tracked over periods as short as one year, with annual reductions of between 0.5% and 1.0% in most brain areas. (2) The volumetric brain reductions in healthy aging are likely only to a minor extent related to neuronal loss. Rather, shrinkage of neurons, reductions of synaptic spines, and lower numbers of synapses probably account for the reductions in grey matter. In addition, the length of myelinated axons is greatly reduced, up to almost 50%. (3) Reductions in specific cognitive abilities--for instance processing speed, executive functions, and episodic memory--are seen in healthy aging. Such reductions are to a substantial degree mediated by neuroanatomical changes, meaning that between 25% and 100% of the differences between young and old participants in selected cognitive functions can be explained by group differences in structural brain characteristics.
Do Peers Make the Place? Conceptual Synthesis and Meta-Analysis of Coworker Effects on Perceptions, Attitudes, OCBs, and Performance

The authors propose that broad aspects of lateral relationships, conceptualized as coworker support and coworker antagonism, are linked to important individual employee outcomes (role perceptions, work attitudes, withdrawal, and effectiveness) in a framework that synthesizes several theoretical predictions. From meta-analytic tests based on 161 independent samples and 77,954 employees, the authors find support for most of the proposed linkages. Alternative explanations are ruled out, as results hold when controlling for leader influences and mediation processes. The authors also observe differential strengths of coworker influence based on its valence, content, and severity, and on the social intensity of the task environment. The authors conclude with a call for more comprehensive, complex theory and investigation of coworker influences as part of the social environment at work.
Tipranavir (TPV) Genotypic Inhibitory Quotient Predicts Virological Response at 48 Weeks to TPV-Based Salvage Regimens

ABSTRACT The virological response (VR) to a tipranavir-ritonavir (TPV-RTV)-based regimen had been shown to be associated with a number of mutations in the protease gene, the use of enfuvirtide (T20), and the TPV phenotypic inhibitory quotient (IQ). The role of the TPV genotypic IQ (gIQ) has not yet been fully investigated. The aim of our study was to evaluate the relationship between the TPV gIQ and the VR at 48 weeks to TPV-based salvage regimens. Patients placed on regimens containing two nucleoside reverse transcriptase inhibitors plus TPV-RTV 500/200 mg twice a day with or without T20 were prospectively studied. Regular follow-up was performed over the study period. VR, considered a viral load (VL) decrease of ≥1 log unit and/or the achievement of <50 copies/ml with no VL rebound of >0.5 log unit compared to the maximal VL decrease at week 48, was assessed. Thirty-eight patients who had received multiple drugs were included. At week 48 the VL decrease was −1.48 (interquartile range [IQR], −2.88 to −0.48), 15 patients (39.5%) had VLs of <50 copies/ml, and the CD4+ cell count increase was 37 cells/mm3 (IQR, −30 to +175). Twenty subjects (52.6%) achieved VRs. The TPV gIQ and optimized background score (OBS) were independently associated with higher VL decreases. The TPV gIQ and OBS were also independent predictors of a VR at week 48. TPV gIQ and OBS cutoff values of 14,500 and 2, respectively, were associated with a higher rate of VR. The TPV gIQ was shown to be able to predict the VR at 48 weeks to TPV-containing salvage regimens better than the TPV trough concentration or TPV-associated mutations alone. A possible TPV gIQ cutoff value of 14,500 for reaching a VR at week 48 was suggested. Further studies are needed in order to evaluate the calculation of TPV gIQ as a new tool for the optimization of TPV-based salvage therapy.
Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women

Obesity is associated with complications during pregnancy and increased health risks in the newborn. The objective of the present study was to establish possible relationships between gut microbiota, body weight, weight gain and biochemical parameters in pregnant women. Fifty pregnant women were classified according to their BMI in normal-weight (n 34) and overweight (n 16) groups. Gut microbiota composition was analysed by quantitative real-time PCR in faeces and biochemical parameters in plasma at 24 weeks of pregnancy. Reduced numbers of Bifidobacterium and Bacteroides and increased numbers of Staphylococcus, Enterobacteriaceae and Escherichia coli were detected in overweight compared with normal-weight pregnant women. E. coli numbers were higher in women with excessive weight gain than in women with normal weight gain during pregnancy, while Bifidobacterium and Akkermansia muciniphila showed an opposite trend. In the whole population, increased total bacteria and Staphylococcus numbers were related to increased plasma cholesterol levels. Increased Bacteroides numbers were related to increased HDL-cholesterol and folic acid levels, and reduced TAG levels. Increased Bifidobacterium numbers were related to increased folic acid levels. Increased Enterobacteriaceae and E. coli numbers were related to increased ferritin and reduced transferrin, while Bifidobacterium levels showed the opposite trend. Therefore, gut microbiota composition is related to body weight, weight gain and metabolic biomarkers during pregnancy, which might be of relevance to the management of the health of women and infants.
A clock tree topology extraction algorithm for improving the tolerance of clock distribution networks to delay uncertainty

The design of clock distribution networks in synchronous systems presents enormous challenges. Control of the clock signal delay in the presence of various noise sources, process parameter variations, and environmental effects represents one of the fundamental problems in the design of high speed synchronous circuits. An algorithm that improves the tolerance of a clock distribution network to process and environmental variations is presented in this paper. The algorithm generates a clock tree topology that minimizes the uncertainty of the clock signal delay in the most critical data paths. Details of the algorithm and preliminary results on benchmark circuits are presented.
Spike timing reliability in the prefrontal cortex depends on the frequency content of its synaptic i

A periscopic rear view optical system for vehicles in which an image of a rearward objective is reflected downwardly from a rooftop mirror through a prismatic device constructed as a transparently faced housing filled with a liquid suitable for the optical path to be within the critical angle at the desired reflective faces for reflection of the image to the driver of the vehicle. A modification of the device includes adjustable prism faces to accommodate different driver heights, with the spatial dimension variations produced by the adjustment effecting a vertical movement of the device.
Compound Word Recombination for German LVCSR

Compound words are a difﬁculty for German speech recognition systems since they cause high out-of-vocabulary and word error rates. State of the art approaches augment the language model by the fragments of compounds in order to increase lexical coverage, lower the perplexity and out-of-vocabulary rate. The fragments are tagged in order to concatenate subsequent equally tagged fragments in the recognition result, but this does not guarantee the recombination of proper words. Such recombination techniques neglect the large vocabulary of the language model training data for recombination although most compounds are covered by it. In this paper, we investigate the use of this vocabulary for the recombination of compound words from the recognition result. The approach is tested on two large vocabulary tasks on top of full-word and fragment based language models and achieves good improvements of 3– 7% relative over the baseline compound-sensitive word error rate.
Dual Rooted-Diffusions for Clustering and Classification on Manifolds

We introduce a new similarity measure between data points suited for clustering and classification on smooth manifolds. The proposed measure is constructed from a dual rooted graph diffusion over the feature vector space, obtained by growing dual rooted minimum spanning trees (MST) between data points. This diffusion model for pairwise affinities naturally accommodates the case where the feature distribution is supported on a lower dimensional manifold. When this affinity measure is combined with labeled data, a semi-supervised classifier can be defined that handles both labeled and unlabeled data in a seamless manner. We will illustrate our method for both simulated ground truth and real partially labeled data sets
Chemically Induced Mutants of Brassica oleracea var. botrytis Maintained Stable Resistance to Drought and Salt Stress after Regeneration and Micropropagation

Investigation was made to confirm the stability of drought and salt stress tolerance in cauliflower (Brassica oleracea var.botrytis) mutants after regeneration and micropropagation. The N-nitroso-N-ethyleurea (NEU) and N-nitroso-N-methylurea (NMU) induced mutants of cauliflower were created and screened for drought and salt stress tolerance. The highly tolerant mutants were selected, regenerated by tissue culture techniques, screened again for drought and salt tolerance under in-vitro and in-vivo conditions, correlated the response of in-vitro and in-vivo plants within a clone. Free proline levels in clones were correlated with stress tolerance. Results confirmed the persistence of mutations in clones with enhanced resistance levels to stresses over control plants. The regenerated in-vitro and in-vivo plants within a clone showed a positive significant correlation for drought (R2 = 0.663) and salt (R2 = 0.647) resistance that confirms the stability of mutation in clones after generations. Proline showed a positive and significant correlation with drought (R2 = 0.524) and salt (R2 = 0.786) tolerance. Conclusively, drought and salt resistance can be successfully enhanced in cauliflower by chemical mutagenesis. Further molecular analysis is recommended to study these mutants.
Bis(2,9-dimethyl-1,10-phenanthroline)copper(I) pentacyanidonitrosoferrate(II)

The asymmetric unit of the title complex [Cu(C14H12N2)2]2[Fe(CN)5(NO)], consists of a [Cu(dmp)2]+ cation (dmp is 2,9-dimethyl-1,10-phenanthroline) and half an [Fe(CN)5(NO)]2− anion. The anion is disordered across an inversion center with the FeII ion slightly offset (ca 0.205Å) from the inversion center in the direction of the disordered trans-coordinating CN/NO ligands. The anion has a distorted octahedral coordination geometry. The CuI ion is coordinated by two phenanthroline ligands in a distorted tetrahedral geometry. The dihedral angle between the phenanthroline ligands is 77.16 (4) Å. In the crystal, the cations are connected to the anions by weak C—H⋯N hydrogen bonds. In addition, weak π–π stacking interactions are observed, with centroid–centroid distances in the range 3.512 (3)–3.859 (3) Å.
Developing the Models of Service Quality Gaps: A Critical Discussion

High service quality is imperative and important for competitiveness of service industry. In order to provide much quality service, a deeper research on service quality models is necessary. There are plenty of service quality models which enable managers and practitioners to identify quality problems and improve the efficiency and profitability of overall performance. One of the most influential models in the service quality literature is the model of service quality gaps. In this paper, the model of service quality gaps has been critically reviewed and developed in order to make it more comprehensive. The developed model has been verified based using a survey on 16 experts. Compared to the traditional models, the proposed model involves five additional components and eight additional gaps.
Enhance Your Team-Based Qualitative Research

PURPOSE Qualitative research projects often involve the collaborative efforts of a research team. Challenges inherent in teamwork include changes in membership and differences in analytical style, philosophy, training, experience, and skill. This article discusses teamwork issues and tools and techniques used to improve team-based qualitative research. METHODS We drew on our experiences in working on numerous projects of varying, size, duration, and purpose. Through trials of different tools and techniques, expert consultation, and review of the literature, we learned to improve how we build teams, manage information, and disseminate results. RESULTS Attention given to team members and team processes is as important as choosing appropriate analytical tools and techniques. Attentive team leadership, commitment to early and regular team meetings, and discussion of roles, responsibilities, and expectations all help build more effective teams and establish clear norms. As data are collected and analyzed, it is important to anticipate potential problems from differing skills and styles, and how information and files are managed. Discuss analytical preferences and biases and set clear guidelines and practices for how data will be analyzed and handled. As emerging ideas and findings disperse across team members, common tools (such as summary forms and data grids), coding conventions, intermediate goals or products, and regular documentation help capture essential ideas and insights. CONCLUSIONS In a team setting, little should be left to chance. This article identifies ways to improve team-based qualitative research with more a considered and systematic approach. Qualitative researchers will benefit from further examination and discussion of effective, field-tested, team-based strategies.