Miracle-dz/UniFAR-FTUs huggingface dataset:
Non-Profiled Deep Learning-Based Side-Channel Attacks

Deep Learning has recently been introduced as a new alternative to perform Side-Channel analysis [MPP16]. Until now, studies have been focused on applying Deep Learning techniques to perform Profiled Side-Channel attacks where an attacker has a full control of a profiling device and is able to collect a large amount of traces for different key values in order to characterize the device leakage prior to the attack. In this paper we introduce a new method to apply Deep Learning techniques in a Non-Profiled context, where an attacker can only collect a limited number of side-channel traces for a fixed unknown key value from a closed device. We show that by combining key guesses with observations of Deep Learning metrics, it is possible to recover information about the secret key. The main interest of this method is that it is possible to use the power of Deep Learning and Neural Networks in a Non-Profiled scenario. We show that it is possible to exploit the translation-invariance property of Convolutional Neural Networks [CDP17] against de-synchronized traces also during Non-Profiled side-channel attacks. In this case, we show that this method can outperform classic Non-Profiled attacks such as Correlation Power Analysis. We also highlight that it is possible to break masked implementations in black-box, without leakages combination pre-preprocessing and with no assumptions nor knowledge about the masking implementation. To carry the attack, we introduce metrics based on Sensitivity Analysis that can reveal both the secret key value as well as points of interest, such as leakages and masks locations in the traces. The results of our experiments demonstrate the interests of this new method and show that this attack can be performed in practice.
Biogenesis of zinc storage granules in Drosophila melanogaster

ABSTRACT Membrane transporters and sequestration mechanisms concentrate metal ions differentially into discrete subcellular microenvironments for use in protein cofactors, signalling, storage or excretion. Here we identify zinc storage granules as the insect's major zinc reservoir in principal Malpighian tubule epithelial cells of Drosophila melanogaster. The concerted action of Adaptor Protein-3, Rab32, HOPS and BLOC complexes as well as of the white-scarlet (ABCG2-like) and ZnT35C (ZnT2/ZnT3/ZnT8-like) transporters is required for zinc storage granule biogenesis. Due to lysosome-related organelle defects caused by mutations in the homologous human genes, patients with Hermansky–Pudlak syndrome may lack zinc granules in beta pancreatic cells, intestinal paneth cells and presynaptic vesicles of hippocampal mossy fibers. Summary: Drosophila genes required for the biogenesis of lysosome-related organelles (eye pigment granules) also function in the formation of zinc storage granules in the insect's excretory organ, the Malpighian tubules.
NuSTAR REVEALS EXTREME ABSORPTION IN z < 0.5 TYPE 2 QUASARS

The intrinsic column density (NH) distribution of quasars is poorly known. At the high obscuration end of the quasar population and for redshifts z < 1, the X-ray spectra can only be reliably characterized using broad-band measurements that extend to energies above 10 keV. Using the hard X-ray observatory NuSTAR, along with archival Chandra and XMM-Newton data, we study the broad-band X-ray spectra of nine optically selected (from the SDSS), candidate Compton-thick (NH > 1.5 × 1024 cm−2) type 2 quasars (CTQSO2s); five new NuSTAR observations are reported herein, and four have been previously published. The candidate CTQSO2s lie at z < 0.5, have observed [O iii] luminosities in the range 8.4 < log ( L [ O III ] / L ⊙ ) < 9.6 ? > , and show evidence for extreme, Compton-thick absorption when indirect absorption diagnostics are considered. Among the nine candidate CTQSO2s, five are detected by NuSTAR in the high-energy (8–24 keV) band: two are weakly detected at the ≈3σ confidence level and three are strongly detected with sufficient counts for spectral modeling (≳90 net source counts at 8–24 keV). For these NuSTAR-detected sources direct (i.e., X-ray spectral) constraints on the intrinsic active galactic nucleus properties are feasible, and we measure column densities ≈2.5–1600 times higher and intrinsic (unabsorbed) X-ray luminosities ≈10–70 times higher than pre-NuSTAR constraints from Chandra and XMM-Newton. Assuming the NuSTAR-detected type 2 quasars are representative of other Compton-thick candidates, we make a correction to the NH distribution for optically selected type 2 quasars as measured by Chandra and XMM-Newton for 39 objects. With this approach, we predict a Compton-thick fraction of f CT = 36 − 12 + 14 ? > %, although higher fractions (up to 76%) are possible if indirect absorption diagnostics are assumed to be reliable.
Study on Compressive Strength of Recycled Aggregate Concrete

Experimental work for the compressive strength of recycled aggregate concrete was designed and performed with 264 cubes. The results indicated that the recycled coarse aggregate (RCA) replacement ratio has a remarkable influence on the compressive strength of recycled aggregate concrete,the relationships between the compressive strength and the m w/m c ratio are also different for different RCA replacement ratios and the developments for the compressive strength of recycled aggregate concrete are not exactly the same as that of normal concrete.Nevertheless, the compressive strength of recycled aggregate concrete can achieve the target compressive strength by adjusting the m w/m c ratio. Finally, based on the test results, the m w/m c ratio for achieving a target strength of 30 MPa for concrete with different RCA replacement ratios is presented.
Safety evaluation of zinc methionine in laying hens: Effects on laying performance, clinical blood parameters, organ development, and histopathology

ABSTRACT The study was conducted to investigate whether high‐dose zinc methionine (Zn‐Met) affected the safety of laying hens, including laying performance, hematological parameters, serum chemical parameters, organ index, and histopathology. A total of 540 20‐week‐old Hy‐Line White laying hens was randomly allocated to 6 groups with 6 replicates of 15 birds each. Birds were fed diets supplemented with 0 (control), 70, 140, 350, 700, or 1,400 mg Zn/kg diet as Zn‐Met. The experiment lasted for 8 wk after a 2‐week acclimation period. Results showed that dietary supplementation with 70 or 140 mg Zn/kg diet as Zn‐Met significantly increased average daily egg mass (ADEM), laying rate (LR), and feed conversion ratio (FCR) (P < 0.05) and lowered broken and soft‐shelled egg ratio (BSER) (P < 0.05) in comparison with the control group; no significant differences were detected among hens fed with 0, 350, or 700 mg Zn/kg as Zn‐Met (P > 0.05); hens administered 1,400 mg Zn/kg showed a significant increase in BSER and remarkable decreases in ADEM, LR, and FCR (P < 0.001). There were no significant differences among hens receiving 0, 70, 140, 350, or 700 mg Zn/kg as Zn‐Met in serum chemical parameters (P > 0.05); supplementation with 1,400 mg Zn/kg as Zn‐Met remarkably elevated the concentrations of serum total bilirubin (TBILI), glucose (GLU), uric acid (UA), and creatinine (CRE) (P < 0.001), and enhanced activities of serum glutamic oxalacetic transaminase (GOP) and alkaline phosphatase (AKP) (P < 0.001) compared with the control group. No significant histopathological changes were found in hens administered 0, 70, 140, 350, or 700 mg Zn/kg as Zn‐Met, while significant histological lesions were observed in the heart, liver, lung, and kidney tissues of hens receiving 1,400 mg Zn/kg as Zn‐Met. No significant differences were detected in hematological parameters or organ index (P > 0.05). In conclusion, a nominal Zn concentration of 700 mg/kg as Zn‐Met is considered to be no‐observed‐adverse‐effect level following daily administration to hens for 56 days.
Disease Resistance in Plants

VOL. 3, No. 6, of the Proceedings of the Indian Academy of Sciences is devoted entirely to the papers submitted for the symposium at Coimbatore in October 1935 on “Disease Resistance in Plants”. Interest in the contributions lies in methods of stimulating disease resistance. These are adopted as a result of investigations along the lines of inheritance of resistance, structural modification associated with resistance and physiological conditions associated with the plants' response to the disease. Thus in the case of sugar-cane, frequently attacked by mosaic, N. L. Dutt, Syed Abbas Hussainy and M. K. Krishnaswami; C. S. Krishnaswami, and others, have found it possible to breed resistant plants and that those with Saccharum spontaneum parentage are more resistant than others.
Epidemiology and treatment of distal radius fractures in Reykjavik, Iceland, in 2004

Background and purpose Recent literature suggests that the incidence and treatment modalities of distal radius fractures have been changing over the past 2 decades in the developed world. We examined the epidemiology of adult distal radius fractures in Iceland in 2004 and compared it with an Icelandic study from 1985 and other studies. Methods A retrospective study of the epidemiology, classification, and treatment of distal radius fractures in Reykjavik residents aged 16 and older in 2004 was conducted by analysis of medical records and re-evaluation of all radiographic examinations. Results The 228 fractures included in our material yielded an overall annual incidence of 17/104 in men and 37/104 in women. Age-specific incidence rose steadily with age in both sexes. One third of the fractures were intraarticular, and working-age men accounted for a large proportion of them. 95% of fractures were treated nonoperatively. Interpretation The annual incidence of distal radius fractures was similar in 1985 and 2004. However, age-specific incidence in younger postmenopausal women decreased sharply. This trend has also been observed in recent Scandinavian studies. Most fractures were treated nonoperatively in Iceland in 2004.
Emotion regulation and emotional distress: The mediating role of hope on reappraisal and anxiety/depression in newly diagnosed cancer patients

A proportion of newly diagnosed cancer patients may experience anxiety and depression. Emotion suppression has been associated with poorer psychoemotional outcomes, whereas reappraisal may be an adaptive emotion regulation strategy. Few studies have examined potential mechanisms linking reappraisal to psychoemotional outcomes in cancer patients. This study aims to replicate findings on reappraisal and suppression and further examines if hope mediates the association between reappraisal and anxiety/depression in patients newly diagnosed with cancer.
A qualitative study exploring women’s journeys to becoming smokers in the social context of urban India

ABSTRACT In India, the prevalence of smoking among women is increasing, and the reasons behind this are unclear. We aimed to study the factors leading to initiation and maintenance of the smoking habit in women in Pune, India. Twenty-seven urban women smokers, ranging from 21 to 60 years of age (31.96 ± 10.70 years), were interviewed between September 2015 and February 2016. The in-depth interviews consisted of questions on pre-decided categories, including initiation, motivation to continue smoking, and risk perception. Thematic analysis revealed that peer pressure, curiosity, fascination, experimentation, and belonging to a group were factors that led to initiation, while lack of alternatives for stress relief, work environments, and lack of leisure time activities provided circumstances to continue smoking. Participants recognized a sense of liberation and independence from smoking cigarettes and perceived health risks as minor and distant. These findings can be used to develop or modify interventions to prevent and control smoking among urban Indian women.
Cost-effectiveness of Store-and-Forward Teledermatology: A Systematic Review.

IMPORTANCE Teledermatology is a topical clinical approach being tested in Australia and elsewhere. With most dermatologists residing in metropolitan areas, teledermatology provides an apparent low-cost and convenient means of access for individuals living outside these areas. It is important that any proposed new addition to a health care system is assessed on the grounds of economic cost and effectiveness. OBJECTIVE To summarize and evaluate the current economic evidence comparing store-and-forward teledermatology (S&FTD) with conventional face-to-face care. EVIDENCE REVIEW Search terms with appropriate amendments were used to identify S&FTD articles that included economic analysis. Six databases were searched, and title, abstract and full-text reviews were conducted by 2 researchers. References of all unique returned articles were searched by hand. The Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist was used to evaluate quality of the included articles. FINDINGS Eleven articles were selected for inclusion, including 1 cost analysis, 4 cost-minimization analyses, 4 cost-effectiveness analyses, and 2 cost-utility analyses. CHEERS scores ranged from 7 to 21 out of a possible 24 points, with a median score of 17. CONCLUSIONS AND RELEVANCE Current evidence is sparse but suggests that S&FTD can be cost-effective. It appears to be cost-effective when used as a triage mechanism to reduce face-to-face appointment requirements. The cost-effectiveness of S&FTD increases when patients are required to travel farther distances to access dermatology services. Further economic research is required for the emerging S&FTD, which uses dermoscopes in combination with smartphone applications, as well as regarding the possibility and consequences of patients self-capturing and transmitting images.
The Utility of EEG in Attention Deficit Hyperactivity Disorder: A Replication Study

The routine use of stimulants in pediatrics has increased dramatically over the past 3 decades and the long-term consequences have yet to be fully studied. Since 1978 there have been 7 articles identifying electroencephalogram (EEG) abnormalities, particularly epileptiform discharges in children with attention deficit hyperactivity disorder (ADHD). Many have studied the prevalence of these discharges in this population with varying results. An article published in 2011 suggests that EEG technology should be considered prior to prescribing stimulants to children diagnosed with ADHD due to a high prevalence of epileptiform discharges. The 2011 study found a higher prevalence (26%) of epileptiform discharges when using 23-hour and sleep-deprived EEGs in comparison with other methods of activation (hyperventilation or photostimulation) and conventional EEG. We sought to replicate the 2011 results using conventional EEG with the added qEEG technologies of automatic spike detection and low-resolution electromagnetic tomography analysis (LORETA) brain mapping. Our results showed 32% prevalence of epileptiform discharges, which suggests that an EEG should be considered prior to prescribing stimulant medications.
Gender/Sex Differences in the Relationship between Psychosocial Work Exposures and Work and Life Stress

Objectives Stress is an important factor affecting the health of working population. While work exposures are determinants of levels of work and life stress, we do not know whether similar or different exposures are related to stress levels for men and women. This study aimed to formally examine male/female differences in the relationships between psychosocial work exposures and work and life stress in a representative sample of Canadian labour market participants. Methods We used data from 2012 cycle of the Canadian Community Health Survey (CCHS), a representative population-based survey conducted by Statistics Canada. The sample was restricted to employed labour force participants working 15+ hours per week (N = 8328, 48% female). To examine the relationship between work exposures and work and life stress, we conducted path analyses. Psychosocial work exposures included social support, job insecurity, job control, and job strain. Differences between estimates for men and women were explored using multigroup analyses, constraining paths between male and female models to be equivalent and examining the impact on change in model fit. Results Male/female differences were observed in the relationships between supervisor support and work stress levels as well as between job control, job insecurity, job strain, and life stress levels. Higher levels of supervisor support at work were associated with lower work stress among women, but not among men. Low job control had a direct protective effect on life stress for men but not for women, while high job strain had a direct adverse effect on life stress among women but not among men. Higher job insecurity was more strongly associated with higher life stress among men compared with women. The relationship between work stress and life stress was similar among men and women. Discussion The findings of this study suggest that the relationships between psychosocial exposures and work and life stress differ for men and women. Our study also raised important questions about which work exposures are considered when assessing work stress, with level of job control not related to work stress but associated with levels of life stress among men. Conclusion Our study highlights the role of psychosocial work environment for both work and life stress and suggests differences in the importance of specific psychosocial work dimensions for feelings of stress among men and women, and for work stress versus life stress. Future study designs should ensure that measures are included to better disentangle the relative contribution of social and biological factors in explaining these differences among men and women.
Evaluating the Association Between Acute and Chronic Pain After Surgery: Impact of Pain Measurement Methods

Aim/Objectives/Background: There is a need to predict chronic (Z3mo) postsurgical pain (CPSP). Acute (<7 d) pain is a predictor, that is, more severe pain is associated with higher CPSP risk. However, reported associations vary widely. Methods: Using a systematic search, we examined associations between 2 acute pain measures (pain at rest [PAR] and movement-evoked pain [MEP]) and CPSP outcomes (considering severity vs. any “nonzero” pain only) in 22 studies. Results: Seven studies reported the relationship between CPSP and both PAR and MEP. Of these, 2/7 reported no association, 3/7 reported significant associations for both PAR and MEP, 1/7 reported an association for PAR only, and 1/7 reported an association for MEP only. Six of another 7 studies reporting only the association for MEP found a significant relationship. Three of the 5 studies that did not specify whether acute pain outcomes were PAR or MEP reported a significant relationship. Another 3 studies reporting a relationship with CPSP did not specify whether this was for PAR, MEP, or both. All investigations incorporating severity of CPSP in their analyses (n=7) demonstrated a significant relationship, whereas only 10 of the 15 studies that dichotomized CPSP outcome as “no pain” versus “any”/“nonzero pain” were positive. Conclusions: Overall, evidence for an association between acute and chronic pain is moderate at best. However, closer attention to pain measurement methods will clarify the relationships between acute pain and CPSP. We propose that future CPSP predictor studies assess both PAR and MEP acutely and also incorporate CPSP severity in their analyses.
Generalization versus Specialization in Pollination Systems: Visitors, Thieves, and Pollinators of Hypoestes aristata (Acanthaceae)

Many recent studies have suggested that the majority of animal-pollinated plants have a higher diversity of pollinators than that expected according to their pollination syndrome. This broad generalization, often based on pollination web data, has been challenged by the fact that some floral visitors recorded in pollination webs are ineffective pollinators. To contribute to this debate, and to obtain a contrast between visitors and pollinators, we studied insect and bird visitors to virgin flowers of Hypoestes aristata in the Bamenda Highlands, Cameroon. We observed the flowers and their visitors for 2-h periods and measured the seed production as a metric of reproductive success. We determined the effects of individual visitors using 2 statistical models, single-visit data that were gathered for more frequent visitor species, and frequency data. This approach enabled us to determine the positive as well as neutral or negative impact of visitors on H. aristata’s reproductive success. We found that (i) this plant is not generalized but rather specialized; although we recorded 15 morphotaxa of visitors, only 3 large bee species seemed to be important pollinators; (ii) the carpenter bee Xylocopa cf. inconstans was both the most frequent and the most effective pollinator; (iii) the honey bee Apis mellifera acted as a nectar thief with apparent negative effects on the plant reproduction; and (iv) the close relationship between H. aristata and carpenter bees was in agreement with the large-bee pollination syndrome of this plant. Our results highlight the need for studies detecting the roles of individual visitors. We showed that such an approach is necessary to evaluate the pollination syndrome hypothesis and create relevant evolutionary and ecological hypotheses.
Pericyte-Derived Dickkopf2 Regenerates Damaged Penile Neurovasculature Through an Angiopoietin-1-Tie2 Pathway

Penile erection requires well-coordinated interactions between vascular and nervous systems. Penile neurovascular dysfunction is a major cause of erectile dysfunction (ED) in patients with diabetes, which causes poor response to oral phosphodiesterase-5 inhibitors. Dickkopf2 (DKK2), a Wnt antagonist, is known to promote angiogenesis. Here, using DKK2-Tg mice or DKK2 protein administration, we demonstrate that the overexpression of DKK2 in diabetic mice enhances penile angiogenesis and neural regeneration and restores erectile function. Transcriptome analysis revealed that angiopoietin-1 and angiopoietin-2 are target genes for DKK2. Using an endothelial cell-pericyte coculture system and ex vivo neurite sprouting assay, we found that DKK2-mediated juxtacrine signaling in pericyte-endothelial cell interactions promotes angiogenesis and neural regeneration through an angiopoietin-1-Tie2 pathway, rescuing erectile function in diabetic mice. The dual angiogenic and neurotrophic effects of DKK2, especially as a therapeutic protein, will open new avenues to treating diabetic ED.