Miracle-dz/UniFAR-FTUs huggingface dataset:
A comparison of piezoelectric transformer AC/DC converters with current doubler and voltage doubler rectifiers

The objective of this study was to develop recommendations for an optimal design of piezoelectric transformer (PT) AC/DC converters. The paper presents a comprehensive comparison of the two commonly used rectifier topologies in a PT based power converters: current doubler and voltage doubler rectifiers. The advantages and disadvantages of the two rectifiers were investigated and the range of their applications with respect to output current, voltage, power capability, load resistance etc.-was delineated. Generic parameters are proposed and used to derive normalized and closed form equations that can help choosing a PT for a given set of requirements. Simulation and experimental results were found to be in a good agreement with the derivation of the theoretical analysis.
Patient-Reported Outcomes following Split-Face Injection of 2 Volumizing Fillers in the Upper Cheeks

Background: Patient-reported outcomes are important measures when assessing the efficacy of aesthetic procedures. Objective: To compare outcomes between 2 volumizing hyaluronic acid fillers. Materials and Methods: Subjects with moderate-to-severe volume loss in the cheeks were randomized in a split-face design to malar enhancement with Cohesive Polydensified Matrix 26 mg/ml HA (CPM-26) and Vycross 20 mg/ml HA (VYC-20). The same injection technique and injection volume were applied for both sides of the face. Anesthetics, overcorrection, and touch-ups were not permitted. Blinded subjects assessed aesthetic improvements using the Global Aesthetic Improvement Scale and treatment satisfaction by confirming their willingness to repeat treatment or recommend it to friends. Follow-up was 18 months. Results: A total of 45 subjects received a single 2 mL injection of CPM-26 on one side and VYC-20 on the contralateral side of the face. The proportion of subjects reporting improvement on the Global Aesthetic Improvement Scale compared with baseline for CPM-26 and VYC-20 was 97.7% and 88.6%, respectively, at 3 months, 73.8% and 71.1% at 12 months, and 61.0% and 56.7% at 18 months. Treatment satisfaction was high, with the majority of subjects stating that they would repeat treatment and recommend it to friends, but at each time point, a higher proportion of subjects was more satisfied with the CPM-26-treated side of the face. Conclusions: In this first direct comparison of CPM-26 and VYC-20, the majority of subjects were satisfied with both treatments throughout the study. Patient-reported outcome measures identified a trend in favor of CPM-26.
Colorization by example

We present a new method for colorizing grayscale images by transferring color from a segmented example image. Rather than relying on a series of independent pixel-level decisions, we develop a new strategy that attempts to account for the higher-level context of each pixel. The colorizations generated by our approach exhibit a much higher degree of spatial consistency, compared to previous automatic color transfer methods [WAM02]. We also demonstrate that our method requires considerably less manual effort than previous user-assisted colorization methods [LLW04]. Given a grayscale image to colorize, we first determine for each pixel which example segment it should learn its color from. This is done automatically using a robust supervised classification scheme that analyzes the low-level feature space defined by small neighborhoods of pixels in the example image. Next, each pixel is assigned a color from the appropriate region using a neighborhood matching metric, combined with spatial filtering for improved spatial coherence. Each color assignment is associated with a confidence value, and pixels with a sufficiently high confidence level are provided as "micro-scribbles" to the optimization-based colorization algorithm of Levin et al. [LLW04], which produces the final complete colorization of the image.
Handoff strategies in settings with high consequences for failure: lessons for health care operations.

OBJECTIVE To describe strategies employed during handoffs in four settings with high consequences for failure. DESIGN ANALYSIS of observational data for evidence of use of 21 handoff strategies. SETTING NASA Johnson Space Center in Texas, nuclear power generation plants in Canada, a railroad dispatch center in the United States, and an ambulance dispatch center in Toronto. MAIN MEASURE Evidence of 21 handoff strategies from observations and interviews. RESULTS Nineteen of 21 strategies were used in at least one domain, on at least an 'as needed' basis. CONCLUSIONS An understanding of how handoffs are conducted in settings with high consequences for failure can jumpstart endeavors to modify handoffs to improve patient safety.
Basal Ganglia Mechanisms of Reward‐Oriented Eye Movement

Abstract: Expectation of reward facilitates motor behaviors that enable the animal to approach a location in space where the reward is expected. It is now known that the same expectation of reward profoundly modifies sensory, motor, and cognitive information processing in the brain. However, it is still unclear which brain regions are responsible for causing the reward‐approaching behavior. One candidate is the dorsal striatum where cortical and dopaminergic inputs converge. We tested this hypothesis by injecting dopamine antagonists into the caudate nucleus (CD) while the monkey was performing a saccade task with a position‐dependent asymmetric reward schedule. We previously had shown that: (1) serial GABAergic connections from the CD to the superior colliculus (SC) via the substantia nigra pars reticulata (SNr) exert powerful control over the initiation of saccadic eye movement and (2) these GABAergic neurons encode target position and are strongly influenced by expected reward, while dopaminergic neurons in the substantia nigra pars compacta (SNc) encode only reward‐related information. Before injections of dopamine antagonists the latencies of saccades to a given target were shorter when the saccades were followed by a large reward than when they were followed by a small reward. After injections of dopamine D1 receptor antagonist the reward‐dependent latency bias became smaller. This was due to an increase in saccade latency on large‐reward trials. After injections of D2 antagonist the latency bias became larger, largely due to an increase in saccade latency on small‐reward trials. These results indicate that: (1) dopamine‐dependent information processing in the CD is necessary for the reward‐dependent modulation of saccadic eye movement and (2) D1 and D2 receptors play differential roles depending on the positive and negative reward outcomes.
DNA Barcoding of Parasitic Nematodes: Is it Kosher?

Abstract: Nematode parasites were encountered in kosher-certified fish meat and roe, and the question was raised as to whether or not these food products were kosher as concerns food preparation standards—a matter that pertains to the identity and, by extension, the life cycle of the parasites. To ascertain the identities of parasitic nematodes, given the distorted or damaged nature of the specimens, molecular techniques were applied in the form of DNA barcoding. To our knowledge, this is the first application of this technique to an obviously cultural concern as opposed to one of health or economic significance. Results, based both on cytochrome c oxidase subunits I and II, suggested that the parasite species found in the fish products are anisakine species that do not inhabit the intestinal lumen of the fish hosts examined. Thus, there was no evidence of failure to adhere to food preparation practices consistent with the proscriptions of Orthodox Judaism. Notwithstanding the success of DNA barcoding in determining at least the higher taxonomic identities of the parasites, some shortcomings of the DNA barcoding pipeline as it pertains to nematode parasites were encountered; specifically, the paucity of data available for the DNA barcoding locus, even for very common nematode taxa.
YNU-HPCC at IJCNLP-2017 Task 1: Chinese Grammatical Error Diagnosis Using a Bi-directional LSTM-CRF Model

Building a system to detect Chinese grammatical errors is a challenge for natural-language processing researchers. As Chinese learners are increasing, developing such a system can help them study Chinese more easily. This paper introduces a bi-directional long short-term memory (BiLSTM) - conditional random field (CRF) model to produce the sequences that indicate an error type for every position of a sentence, since we regard Chinese grammatical error diagnosis (CGED) as a sequence-labeling problem.
Influence of lactation stages and rain periods on subclinical mastitis in meat producing ewes

Mastitis negatively influences the survival and weight gain of ovines for meat production. The purpose of this study was to investigate, in sheep for meat production, the occurrence of subclinical mastitis in ewes at the end of lactation and beginning of the consecutive lactation and to assess the composition and cellular characteristics of milk as a function of different rainfall indices. Mammary halves (821) of Santa Ines (479) and Morada Nova (342) ewes were examined. Milk samples were collected in two different moments of lactation: at weaning and postpartum of the consecutive lactation. Sample collection periods were called "dry" or "rainy" according to the rainfall index in the month immediately before the month of collection. The occurrence of subclinical mastitis at weaning in the Santa Ines and Morada Nova ewes were 16.4 and 12.6% in the dry period, and 17.7 and 23.5% in the rainy period, respectively. In the consecutive lactation period, the occurrences were 26.7 and 27.7% in the dry period and 41.8 and 39.1% in the rainy period, for the Santa Ines and Morada Nova ewes, respectively. Postpartum stage was critical for the occurrence of subclinical mastitis, as compared to that at the end of the previous lactation. Occurrence of the disease negatively influenced the SCC in the milk at the beginning of lactation and changed its composition, mainly in the rainiest periods, probably due to a difficulty in maintaining hygiene in the environment where the animals remained.
Mortality After Acute Myocardial Infarction in Hospitals That Disproportionately Treat Black Patients

Background— African Americans are more likely to be seen by physicians with less clinical training or to be treated at hospitals with longer average times to acute reperfusion therapies. Less is known about differences in health outcomes. This report compares risk-adjusted mortality after acute myocardial infarction (AMI) between US hospitals with high and low fractions of elderly black AMI patients. Methods and Results— A prospective cohort study was performed for fee-for-service Medicare patients hospitalized for AMI during 1997 to 2001 (n=1 136 736). Hospitals (n=4289) were classified into approximate deciles depending on the extent to which the hospital served the black population. Decile 1 (12.5% of AMI patients) included hospitals without any black AMI admissions during 1997 to 2001. Decile 10 (10% of AMI patients) included hospitals with the highest fraction of black AMI patients (33.6%). The main outcome measures were 90-day and 30-day mortality after AMI. Patients admitted to hospitals disproportionately serving blacks experienced no greater level of morbidities or severity of the infarction, yet hospitals in decile 10 experienced a risk-adjusted 90-day mortality rate of 23.7% (95% CI 23.2% to 24.2%) compared with 20.1% (95% CI 19.7% to 20.4%) in decile 1 hospitals. Differences in outcomes between hospitals were not explained by income, hospital ownership status, hospital volume, census region, urban status, or hospital surgical treatment intensity. Conclusions— Risk-adjusted mortality after AMI is significantly higher in US hospitals that disproportionately serve blacks. A reduction in overall mortality at these hospitals could dramatically reduce black-white disparities in healthcare outcomes.
Risk Factors for Preeclampsia in Women from Colombia: A Case-Control Study

Background Preeclampsia (PE) is a multi-causal disease characterized by the development of hypertension and proteinuria in the second half of pregnancy. Multiple risk factors have been associated with the development of PE. Moreover, it is known that these risk factors vary between populations from developed and developing countries. The aim of this study is to identify which risk factors are associated with the development of preeclampsia (PE) among Colombian women. Methods A multi-centre case-control study was conducted between September 2006 and July 2009 in six Colombian cities. Cases included women with PE (n = 201); controls were aged-matched pregnant women (n = 201) without cardiovascular or endocrine diseases for a case-control ratio of 1∶1. A complete medical chart, physical examination and biochemical analysis were completed before delivery. Multivariable logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (CI) of potential risk factors associated with PE. Results The presence of factors present in the metabolic syndrome cluster such as body mass index >31 Kg/m2 (OR = 2.18; 1.14–4.14 95% CI), high-density lipoprotein <1.24 mmol/L (OR = 2.42; 1.53–3.84 95% CI), triglycerides >3.24 mmol/L (OR = 1.60; 1.04–2.48 95% CI) and glycemia >4.9 mmol/L (OR = 2.66; 1.47–4.81 95%CI) as well as being primigravidae (OR = 1.71; 1.07–2.73 95% CI) were associated with the development of PE, after adjusting for other variables. Conclusion Factors present in the cluster of metabolic syndrome and primigravidity were associated with a greater risk of PE among Colombian women. Understanding the role of this cluster of risk factors in the development of PE is of crucial importance to prevent PE and remains to be determined.
The Neural Correlates of Consciousness

The neural correlates of consciousness refer to the relationships between mental states and neural states. This chapter discusses the problem of the association between consciousness and neural activity. Functional imaging plays a major role in identification of the neural correlates of consciousness. This chapter also discusses some of these studies and the implications of their results. Studies of normal sleep and of patients in abnormal states of arousal suggest that activity in cortico-thalamic circuitry is necessary for any kind of conscious experience. A number of areas in sensory cortex have been identified where activity is necessary for the conscious experience of particular objects and features. However, this activity is not sufficient for conscious experience of these objects and features. Additional activity is also required in frontal and parietal regions. While there is evidence about activity that is necessary for conscious experience, nothing is known about activity that is sufficient for conscious experience. Further studies of awareness of the motor system and awareness of other people are needed for the progress in this area. © 2004 Elsevier Inc. All rights reserved.
Synthetic tumor‐specific breakpoint peptide vaccine in patients with chronic myeloid leukemia and minimal residual disease

Imatinib is the current standard frontline therapy for chronic myelogenous leukemia (CML). In the majority of patients, imatinib induces a complete cytogenetic response (CCyR); however, complete molecular responses are infrequent. The Bcr‐Abl fusion creates a unique sequence of amino acids that could constitute a target for immunomodulation.
Effect of resin infiltration on white spot lesions after debonding orthodontic brackets.

PURPOSE To evaluate the effect of application of a resin infiltration material on masking the white spot lesions (WSLs) after bracket removal. METHODS 18 patients participated in this study and were divided into two groups of nine patients each; by a visual score based on the extent of demineralization, according to the classification of the WSLs. Group 1: Visible WSLs without surface disruption and Group 2: WSLs showed a roughened surface but not requiring restoration. Three successive photographs were taken for every patient; immediately after bracket removal, 1 week after oral hygiene measures and after Icon material application. The JPEG images were imported into image analysis software (Image J version 1.33u for Windows XP, US National Institutes of Health) which presented the images into histograms of gray scale from (0 to 255). Initial and final images were compared for percentage of WSLs masking area. RESULTS For both groups, a statistically significant difference at P<0.05 was obtained as follows; for WSLs in Group 1, the means at gray scale for the initial and the final photographs were 126.091 +/- 13.452 and 221.268 +/- 9.350 respectively and they revealed significance by Wilcoxon's signed rank test = 0.038, P<0.05. For WSLs in Group 2, the means at gray scale for the initial and the final photographs were 95.585 +/- 20.973 and 155.612 +/- 31.203 respectively and they revealed significance by Wilcoxon's signed rank test = 0.029, P<0.05.
[Effects of the cutaneous and blood contents of glucose on wound healing in diabetic rats with superficial partial thickness scalding].

OBJECTIVE To study the effect of the cutaneous and blood contents of glucose on wound healing in diabetic rats with superficial partial thickness scalding. METHODS 96 Sprague-Dawley rats were randomized into control group and STZ-induced diabetic group, inflicted with superficial partial thickness scalding of 10% TBSA on the back. The glucose content in the blood and wound tissue were evaluated before injury and at day 1, day 3, day 5, day 7, day 10 and day 14 after injury. Wound healing process in the rats was dynamically observed by naked eyes and histologically examined. The cell cycles of keratinocytes from wound site were determined before injury and at day 3, day 7 and day 10 after injury. RESULTS The concentrations of blood glucose in diabetic wound was significant increased than normal group (27.28 mmol/L +/- 0.80 mmol/L vs. 4.65 mmol/L +/- 0.14 mmol/L, P < 0.01). The content of local glucose in wound tissue were significantly correlated with that in the blood (r = 0.881, P < 0.05). When compared with the control group, wound healing of the diabetic rats were delayed with the characteristics of impaired epithelialization and decreased. percentages of S stage and G(2)/M stages of keratinocytes. CONCLUSION Local glucose content in diabetic wound was varied with blood glucose concentration. The increased glucose concentration in diabetic wound was attributed to the impaired wound healing in diabetes. High glucose concentration could inhibit the epithelialization and decrease the keratinocyte proliferation.
Is Basic Personality Related to Violent and Non-Violent Video Game Play and Preferences?

Based on the uses and gratifications perspective, personality was expected to relate to violent video game play frequency and game preferences. Participants completed measures of personality and frequency of violent video game play, and identified their most frequently played video games. Results indicate that individuals higher in openness but lower in agreeableness played violent video games more frequently. In addition, more open and extroverted but less agreeable and neurotic individuals generally preferred to play video games that are more violent. Results suggest personality may be more predictive of violent video game use than traditional media use, though the predictive personality dimensions may be consistent across media types.
Scalable and progressive audio codec

A source coding technique for variable, bandwidth-constrained channels such as the Internet must do two things: offer high quality at low data rates, and adapt gracefully to changes in available bandwidth. Here we propose an audio coding algorithm that is superior on both counts. It is inherently scalable, meaning that channel conditions can be matched without the need for additional computation. Moreover, it is compact: in subjective tests our algorithm, coded at 32 kb/s/channel, outperformed MPEG-1 Layer 3 (MP3) coded at 56 kb/s/channel (both at 44.1 kHz). We achieve this simultaneous increase in compression and scalability through use of a two-dimensional transform that concentrates relevant information into a small number of coefficients.
Control of nonlinear switched systems based on validated simulation

We present an algorithm of control synthesis for nonlinear switched systems, based on an existing procedure of state-space bisection and made available for nonlinear systems with the help of validated simulation. The use of validated simulation also permits to take bounded perturbations and varying parameters into account. The whole approach is entirely guaranteed and the induced controllers are correct-by-design.
Ku70 and non-homologous end joining protect testicular cells from DNA damage

Summary Spermatogenesis is a complex process that generates haploid germ cells or spores and implements meiosis, a succession of two special cell divisions that are required for homologous chromosome segregation. During prophase to the first meiotic division, homologous recombination (HR) repairs Spo11-dependent DNA double-strand breaks (DSBs) in the presence of telomere movements to allow for chromosome pairing and segregation at the meiosis I division. In contrast to HR, non-homologous end joining (NHEJ), the major DSB repair mechanism during the G1 cell cycle phase, is downregulated during early meiotic prophase. At somatic mammalian telomeres, the NHEJ factor Ku70/80 inhibits HR, as does the Rap1 component of the shelterin complex. Here, we investigated the role of Ku70 and Rap1 in meiotic telomere redistribution and genome protection in spermatogenesis by studying single and double knockout mice. Ku70−/− mice display reduced testis size and compromised spermatogenesis, whereas meiotic telomere dynamics and chromosomal bouquet formation occurred normally in Ku70−/− and Ku70−/−Rap1&Dgr;/&Dgr; knockout spermatocytes. Elevated mid-preleptotene frequencies were associated with significantly increased DNA damage in Ku-deficient B spermatogonia, and in differentiated Sertoli cells. Significantly elevated levels of &ggr;H2AX foci in Ku70−/− diplotene spermatocytes suggest compromised progression of DNA repair at a subset of DSBs. This might explain the elevated meiotic metaphase apoptosis that is present in Ku70-deficient stage XII testis tubules, indicating spindle assembly checkpoint activation. In summary, our data indicate that Ku70 is important for repairing DSBs in somatic cells and in late spermatocytes of the testis, thereby assuring the fidelity of spermatogenesis.
A Behavior-Based Strategy for Single and Multi-Robot Autonomous Exploration

In this paper, we consider the problem of autonomous exploration of unknown environments with single and multiple robots. This is a challenging task, with several potential applications. We propose a simple yet effective approach that combines a behavior-based navigation with an efficient data structure to store previously visited regions. This allows robots to safely navigate, disperse and efficiently explore the environment. A series of experiments performed using a realistic robotic simulator and a real testbed scenario demonstrate that our technique effectively distributes the robots over the environment and allows them to quickly accomplish their mission in large open spaces, narrow cluttered environments, dead-end corridors, as well as rooms with minimum exits.
AN ELECTROPHORETIC EXAMINATION OF A URINARY MUCOPROTEIN WHICH REACTS WITH VARIOUS VIRUSES

A mucoprotein isolated from human urine and possessing the capacity to react with a number of viruses is electrophoretically homogeneous at pH 6.8 and 8.6. After treatment with influenza virus and elimination of its biological activity, the substance remains homogeneous and its electrophoretic mobility is decreased by approximately 20 per cent.