Miracle-dz/UniFAR-FTUs huggingface dataset:
Why Do Men Get More Attention? Exploring Factors Behind Success in An Online Design Community

Online platforms are an increasingly popular tool for people to produce, promote or sell their work. However recent studies indicate that social disparities and biases present in the real world might transfer to online platforms and could be exacerbated by seemingly harmless design choices on the site (for example: recommendation systems or publicly visible success measures). In this paper we analyze an exclusive online community of teams of design professionals called Dribbble and investigate apparent differences in outcomes by gender. Overall, we find that men produce more work, and are able to show it to a larger audience thus receiving more likes. Some of this effect can be explained by the fact that women have different skills and design different images. Most importantly however, women and men position themselves differently in the Dribbble community. Our investigation of users' position in the social network shows that women have more clustered and gender homophilous following relations, which leads them to have smaller and more closely knit social networks. Overall, our study demonstrates that looking behind the apparent patterns of gender inequalities in online markets with the help of social networks and product differentiation helps us to better understand gender differences in success and failure.
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

We have previously shown that dendritic cells isolated after overnight culture, which can express B7 and are potent stimulators of naive T cell proliferation, are relatively poor at inducing the proliferation of a panel of murine T helper 1 (Th1) clones. Maximal stimulation of Th1 clones was achieved using unseparated splenic antigen presenting cells (APC). An explanation for these findings is provided in the present study where we show that FcR+ L cells transfected with B7 stimulate minimal proliferation of Th1 clones in response to anti-CD3 antibodies, in contrast to induction of significant proliferation of naive T cells. However, addition of interleukin 12 (IL-12) to cultures of Th1 cells stimulated with anti-CD3 and FcR+ B7 transfectants resulted in a very pronounced increase in proliferation and interferon gamma (IFN-gamma) production. Exogenous IL-12 did not affect the B7- induced proliferation of naive T cells. This showed that whereas costimulatory signals delivered via B7-CD28 interaction are sufficient to induce significant proliferation of naive T cells activated through occupancy of the T cell receptor, Th1 T cell clones require cooperative costimulation by B7 and IL-12. This costimulation was shown to be specific by inhibition of proliferation and IFN-gamma production using chimeric soluble cytolytic T lymphocyte-associated antigen 4-human IgG1Fc (CTLA4-Ig) and anti-IL-12 antibodies. Furthermore, the significant antigen specific proliferation and IFN-gamma production by Th1 clones observed when splenocytes were used as APC was almost completely abrogated using CTLA4-Ig and anti-IL-12 antibodies. Thus two costimulatory signals, B7 and IL-12, account for the ability of splenic APC to induce maximal stimulation of Th1 clones. IL-10 downregulates the expression of IL-12 by IFN-gamma-stimulated macrophages and this may account largely for t the ability of IL-10 to inhibit APC function of splenic and macrophage APC for the induction of Th1 cell proliferation and IFN-gamma production. Indeed we show that IL-12 can overcome the inhibitory effect of IL-10 for the APC-dependent induction of proliferation and IFN-gamma production by Th1 clones. These results suggest that proliferation by terminally differentiated Th1 clones, in contrast to naive T cells, requires stimulation via membrane-bound B7 and a cytokine, IL-12. It is possible that these signals may result in the activation of unresponsive T cells during an inflammatory response. IL-10, by its role in regulating such innate inflammatory responses, may thus help to maintain these T cells in an unresponsive state.
Word maps and spectra of random graph lifts

We study here the spectra of random lifts of graphs. Let G be a finite connected graph, and let the infinite tree T be its universal cover space. If λ1 and ρ are the spectral radii of G and T respectively, then, as shown by Friedman (Graphs Duke Math J 118 (2003), 19–35), in almost every n‐lift H of G, all “new” eigenvalues of H are ≤ O(λ 11/2 ρ1/2). Here we improve this bound to O(λ 11/3 ρ2/3). It is conjectured in (Friedman, Graphs Duke Math J 118 (2003) 19–35) that the statement holds with the bound ρ + o(1) which, if true, is tight by (Greenberg, PhD thesis, 1995). For G a bouquet with d/2 loops, our arguments yield a simple proof that almost every d‐regular graph has second eigenvalue O(d2/3). For the bouquet, Friedman (2008). has famously proved the (nearly? ) optimal bound of $ 2\sqrt{d - 1} + o(1) $.
Exclusion of RNX as a major gene in congenital central hypoventilation syndrome (CCHS, Ondine's curse)

Congenital central hypoventilation syndrome (CCHS) is a rare condition for which segregation analyses have suggested genetic factors. The respiratory phenotype of Rnx knock‐out mice together with the Rnx expression at the brainstem level prompted us to consider the RNX gene as a candidate for CCHS in human. The screening of the RNX gene in a series of 25 patients with CCHS did not reveal any significant nucleotide variation. We therefore conclude that RNX is not a major gene for CCHS in human. © 2002 Wiley‐Liss, Inc.
Psychological aspects of hypertension. II. The differential influence of interview variables on blood pressure.

The blood pressure responses of normotensive and hypertensive subjects to a three-phase experimental interview situation were recorded. The greatest elevations occurred in both groups during a personal discussion phase, and the elevation was more pronounced among the hypertensive subjects. These results, although based upon a small sample, raise questions about the reliability of clinical blood pressure determinations conducted during or following a medical interview.
Human to robot demonstrations of routine home tasks: Exploring the role of the robot's feedback

In this paper, we explore some conceptual issues, relevant for the design of robotic systems aimed at interacting with humans in domestic environments. More specifically, we study the role of the robot's feedback (positive or negative acknowledgment of understanding) on a human teacher's demonstration of a routine home task (laying a table). Both the human and the system's perspectives are considered in the analysis and discussion of results from a human-robot user study, highlighting some important conceptual and practical issues. These include the lack of explicitness and consistency on people's demonstration strategies. Furthermore, we discuss the need to investigate design strategies to elicit people's knowledge about the task and also successfully advertize the robot's abilities in order to promote people's ability to provide appropriate demonstrations.
Continued fractions and RSA with small secret exponent

Extending the classical Legendre's result, we describe all solutions of the inequality |x - a/b| < c/b^2 in terms of convergents of continued fraction expansion of x. Namely, we show that a/b = (rp_{m+1} +- sp_m) / (rq_{m+1} +- sq_m) for some nonnegative integers m,r,s such that rs < 2c. As an application of this result, we describe a modification of Verheul and van Tilborg variant of Wiener's attack on RSA cryptosystem with small secret exponent.
The Strength and Weakness of Cotton Fibers

Previous work has shown that the structural reversals of cotton fibers are points of weakness at which the fibers prefer to break. The present paper is concerned with the distribution of these reversals in the individual fibers and with differences in reversal frequencies for various cotton varieties. It is shown that indivual fibers vary greatly in their tendency to break at reversals. Fiber reversals are much more frequent at the tip end of the fiber than at the base end. In general, cotton varieties which have high reversal frequencies are weaker cottons as determined by single-fiber and bundle strength tests. The implications of these findings to mechanical properties of the fibers and to their behavior in yarns are discussed.
Community Dynamics of Carrion Flies and their Parasitoids in Experimental Carcasses in Central Argentina

Abstract Insects are the predominant group regarding both species richness and abundance that develop on carrion. Among them, the most important decomposers using carrion as a source of food for their development are the immature stages of the dipteran families Calliphoridae, Muscidae, and Sarcophagidae. The large numbers of their larvae in carcasses are attacked by a rich community of parasitoids, including species of Braconidae, Ichneumonidae, and Pteromalidae (Hymenoptera: Parasitica). The objective of this study was describing the temporal composition and dynamics of a parasitoid community in relation to their dipterans hosts in carrion in terms of number of species and specific composition, irrespective of the particular interactions between species in both trophic levels. Additionally, seasonality of the climate in the region was investigated as a factor structuring the studied communities. The experiments were undertaken in the south of Cordoba, Argentina during 2004 in a rural area. Two traps per season were placed separately approximately 300 m from each other in the study site. Each trap contained a domestic pig (Sus scrofa) of approximately 8 kg as bait. Samples were taken daily during the first four weeks and then every two or three days over the following weeks until the end of the experiment. The dipteran community was represented by 15 species in 6 families of the Calyptratae Diptera whereas parasitoids belonged to six families of the parasitic Apocrita Hymenoptera. Climatic seasonality was an important factor in determining the number of occurring species in the carcasses and community composition. The highest number of species was observed in the spring for both communities.
[The level of the sciatic nerve division and its relations to the piriform muscle].

BACKGROUND The sciatic nerve, as the terminal branch of the sacral plexus, leaves the pelvis through the greater sciatic foramen beneath the piriform muscle. Afterwards, it separates into the tibial and the common peroneal nerve, most frequently at the level of the upper angle of the popliteal fossa. Higher level of the sciatic nerve division is a relatively frequent phenomenom and it may be the cause of an incomplete block of the sciatic nerve during the popliteal block anesthesia. There is a possibility of different anatomic relations between the sciatic nerve or its terminal branches and the piriform muscle (piriformis syndrome). The aim of this research was to investigate the level of the sciatic nerve division and its relations to the piriform muscle. It was performed on 100 human fetuses (200 lower extremities) which were in various gestational periods and of various sex, using microdissection method. Characteristic cases were photographed. RESULTS Sciatic nerve separated into the tibial and common peroneal nerve in popliteal fossa in 72.5% of the cases (bilaterally in the 66% of the cases). In the remainder of the cases the sciatic nerve division was high (27.5% of the cases) in the posteror femoral or in the gluteal region. Sciatic nerve left the pelvis through the infrapiriform foramen in 192 lower extremities (96% of the cases), while in 8 lower extremities (4% of the cases) the variable relations between sciatic nerve and piriform muscle were detected. The common peroneal nerve penetrated the piriform muscle and left the pelvis in 5 lower extremities (2.5% of the cases) and the tibial nerve in those cases left the pelvis through the infrapiriform foramen. In 3 lower extremities (1.5% of the cases) common peroneal nerve left the pelvis through suprapiriform, and the tibial nerve through the infrapiriform foramen. The high terminal division of sciatic nerve (detected in 1/3 of the cases), must be kept in mind during the performing of popliteal block anesthesia. CONCLUSION Although very rare, anatomical abnormalities of common peroneal nerve in regard to piriform muscle are still possible.
Eotaxin Represents the Principal Eosinophil Chemoattractant in a Novel Murine Asthma Model Induced by House Dust Containing Cockroach Allergens1

Asthma represents a serious health problem particularly for inner city children, and recent studies have identified that cockroach allergens trigger many of these asthmatic attacks. This study tested the concept that asthma-like pulmonary inflammation may be induced by house dust containing cockroach allergens. An aqueous extract was prepared from a house dust sample containing endotoxin and high levels of cockroach allergens. BALB/c mice were immunized with the house dust extract (HDE) and received two additional pulmonary challenges. Bronchoalveolar lavage (BAL) eosinophil counts and eotaxin levels were significantly increased in immunized mice exposed to the HDE, whereas neutrophils were the predominant BAL inflammatory cell in the unimmunized mice. Kinetics studies in immunized mice demonstrated a peak pulmonary inflammatory response 48 h after the last challenge. The allergic response in this model was further confirmed by histological and physiological studies demonstrating a significant influx of eosinophils and lymphocytes in the peribronchial area, and severe airway hyperreactivity through whole-body plethysmography. The specificity of the response was established by immunizing with HDE and challenging with purified cockroach allergen, which induced pulmonary eosinophilia and airway hyperreactivity. Ab inhibition of eotaxin significantly inhibited the number of BAL eosinophils. These data describe a novel murine model of asthma-like pulmonary inflammation induced by house dust containing endotoxin and cockroach allergens and further demonstrate that eotaxin represents the principal chemoattractant for the recruitment of the pulmonary eosinophils.
Separable Whorl-Specific Expression and Negative Regulation by Enhancer Elements within the AGAMOUS Second Intron

We analyzed the 4-kb intragenic control region of the AGAMOUS (AG) gene to gain insight into the mechanisms controlling its expression during early flower development. We identified three major expression patterns conferred by 19 AG::reporter gene constructs: the normal AG pattern, a stamen-specific pattern, and a predominantly carpel pattern. To determine whether these three expression patterns were under negative control by APETALA2 (AP2) or LEUNIG (LUG), we analyzed β-glucuronidase staining patterns in Arabidopsis plants homozygous for strong ap2 and lug mutations. Our results indicated that the stamen-specific pattern was independent of AP2 but dependent on LUG; conversely, the carpel-specific pattern was independent of LUG but dependent on AP2. These results lead to a model of control of AG expression such that expression in each of the two inner whorls is under independent positive and negative control.
NOS2 Is Critical to the Development of Emphysema in Sftpd Deficient Mice but Does Not Affect Surfactant Homeostasis

Rationale Surfactant protein D (SP-D) has important immuno-modulatory properties. The absence of SP-D results in an inducible NO synthase (iNOS, coded by NOS2 gene) related chronic inflammation, development of emphysema-like pathophysiology and alterations of surfactant homeostasis. Objective In order to test the hypothesis that SP-D deficiency related abnormalities in pulmonary structure and function are a consequence of iNOS induced inflammation, we generated SP-D and iNOS double knockout mice (DiNOS). Methods Structural data obtained by design-based stereology to quantify the emphysema-like phenotype and disturbances of the intracellular surfactant were correlated to invasive pulmonary function tests and inflammatory markers including activation markers of alveolar macrophages and compared to SP-D (Sftpd−/−) and iNOS single knockout mice (NOS2−/−) as well as wild type (WT) littermates. Measurements and Results DiNOS mice had reduced inflammatory cells in BAL and BAL-derived alveolar macrophages showed an increased expression of markers of an alternative activation as well as reduced inflammation. As evidenced by increased alveolar numbers and surface area, emphysematous changes were attenuated in DiNOS while disturbances of the surfactant system remained virtually unchanged. Sftpd−/− demonstrated alterations of intrinsic mechanical properties of lung parenchyma as shown by reduced stiffness and resistance at its static limits, which could be corrected by additional ablation of NOS2 gene in DiNOS. Conclusion iNOS related inflammation in the absence of SP-D is involved in the emphysematous remodeling leading to a loss of alveoli and associated alterations of elastic properties of lung parenchyma while disturbances of surfactant homeostasis are mediated by different mechanisms.
Tribological behaviour of borided H13 steel with different boriding agents

Solid boriding thermochemical treatment was carried out on AISI H13 steel. Two boriding agents were used: Ekabor 1-V2 commercial powder and a mixture of 73·26 wt-% borax, 24·06 wt-%SiC, 1·22 wt-%NH4Cl and 1·46 wt-%NaCl. Pin on disc wear tests were carried out to investigate tribological behaviour. After the wear tests, samples were cut in cross-section to evaluate the thickness and morphology of the boride layer by scanning electron microscopy (SEM) and Vickers microhardness. Wear mechanisms were evaluated by SEM. A large improvement in wear resistance was observed for borided samples compared with samples that had been quenched and tempered. The thickness of the borided layer was higher for samples borided with Ekabor powder than those borided with the mixture. In comparison with quenched and tempered samples, borided samples had a higher incidence of cracks, which favours spalling and reduction of grooves formed by abrasive wear.
Prenatal Lead Levels, Plasma Amyloid β Levels, and Gene Expression in Young Adulthood

Background: Animal studies suggest that early-life lead exposure influences gene expression and production of proteins associated with Alzheimer’s disease (AD). Objectives: We attempted to assess the relationship between early-life lead exposure and potential biomarkers for AD among young men and women. We also attempted to assess whether early-life lead exposure was associated with changes in expression of AD-related genes. Methods: We used sandwich enzyme-linked immunosorbent assays (ELISA) to measure plasma concentrations of amyloid β proteins Aβ40 and Aβ42 among 55 adults who had participated as newborns and young children in a prospective cohort study of the effects of lead exposure on development. We used RNA microarray techniques to analyze gene expression. Results: Mean plasma Aβ42 concentrations were lower among 13 participants with high umbilical cord blood lead concentrations (≥ 10 μg/dL) than in 42 participants with lower cord blood lead concentrations (p = 0.08). Among 10 participants with high prenatal lead exposure, we found evidence of an inverse relationship between umbilical cord lead concentration and expression of ADAM metallopeptidase domain 9 (ADAM9), reticulon 4 (RTN4), and low-density lipoprotein receptor-related protein associated protein 1 (LRPAP1) genes, whose products are believed to affect Aβ production and deposition. Gene network analysis suggested enrichment in gene sets involved in nerve growth and general cell development. Conclusions: Data from our exploratory study suggest that prenatal lead exposure may influence Aβ-related biological pathways that have been implicated in AD onset. Gene network analysis identified further candidates to study the mechanisms of developmental lead neurotoxicity.
Congenital Cardiovascular Anomalies Induced by Pteroylglutamic Acid Deficiency during Gestation in the Rat

Congenital cardiovascular anomalies were observed in the offspring when rats were placed on a dietary regimen deficient in pteroylglutamic (“folic”) acid during gestation. These cardiovascular malformations occurred only when the mothers were given this diet for specific periods, as short as two or three days, in early pregnancy, at a time when the heart and aortic arches were in the initial stages of development.
Long-Term Memory Is Facilitated by cAMP Response Element-Binding Protein Overexpression in the Amygdala

At least two temporally and mechanistically distinct forms of memory are conserved across many species: short-term memory that persists minutes to hours after training and long-term memory (LTM) that persists days or longer. In general, repeated training trials presented with intervening rest intervals (spaced training) is more effective than massed training (the same number of training trials presented with no or short intervening rest intervals) in producing LTM. LTM requires de novo protein synthesis, and cAMP response element-binding protein (CREB) may be one of the transcription factors regulating the synthesis of new proteins necessary for the formation of LTM. Here we show that rats given massed fear conditioning training show no or weak LTM, as measured by fear-potentiated startle, compared with rats given the same amount of training but presented in a spaced manner. Increasing CREB levels specifically in the basolateral amygdala via viral vector-mediated gene transfer significantly increases LTM after massed fear training. The enhancing effect of CREB overexpression on LTM formation is shown to be specific in terms of biochemistry, anatomy, time course, and the training procedure used. These results suggest that CREB activity in the amygdala serves as a molecular switch for the formation of LTM in fear conditioning.
Size Effects in Electroformed Nanomaterials

This paper reviews size effects in nanocrystalline metals and alloys made by electroforming, a particular form of electrodeposition. The main size effects in these fully dense, three-dimensional nanomaterials come from grain size reduction to less than 5 nm and down towards the limit of the amorphous structure. Details will be given on the synthesis of such materials and their microstructural characteristics including reduced crystal size and intercrystalline defect density. Properties which show either weak or strong grain size dependence will be discussed and compared with the structure-sensitivity of various properties in conventional polycrystalline materials.