Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigating Youth Sports Coaches' Perceptions of Their Role in Adolescent Mental Health

Coaches play an important role in the lives of adolescents in sport and have the potential to greatly impact on athlete mental health. This study aimed to investigate coaches' perceptions of their role in supporting adolescent mental health. Twenty coaches participated in 5 focus groups. Results revealed that coaches perceive their role to be diverse and inclusive of the promotion of mental health. Some believed they have a role in facilitating professional help seeking but were not adequately trained in the area of mental health. We present recommendations regarding the tailoring of mental health literacy training for youth sport coaches.
A Study of Fuel Economy Improvement in a Plug-in Hybrid Electric Vehicle using Engine on/off and Battery Charging Power Control Based on Driver Characteristics

In this study, driving data for various types of drivers are collected using a VIDE (virtual integrated driving environment), and a driver model is developed. To represent the driver tendencies quantitatively, the DDA (degree of driver aggression) is proposed based on fuzzy logic. DDA has a 0-1 value; the closer the DDA is to one, the more aggressive the driver. Using the DDA, an engine on/off and battery charging power control algorithm are developed to improve the fuel economy of a power-split-type plug-in hybrid electric vehicle. The engine on/off control reduces the frequent engine on/off caused by aggressive driving, whereas the battery charging power control maintains the battery state of charge (SOC) by operating the engine according to the DDA. It is found that the proposed control algorithm improves fuel economy by 17.3% compared to the existing control for an aggressive driver.
An Empirical Evaluation of Regression Testing Based on Fix-Cache Recommendations

Background: The fix-cache approach to regression test selection was proposed to identify the most fault-prone files and corresponding test cases through analysis of fixed defect reports. Aim: The study aims at evaluating the efficiency of this approach, compared to the previous regression test selection strategy in a major corporation, developing embedded systems. Method: We launched a post-hoc case study applying the fix-cache selection method during six iterations of development of a multi-million LOC product. The test case execution was monitored through the test management and defect reporting systems of the company. Results: From the observations, we conclude that the fix-cache method is more efficient in four iterations. The difference is statistically significant at alpha = 0.05. Conclusions: The new method is significantly more efficient in our case study. The study will be replicated in an environment with better control of the test execution.
Temporal and spatial alterations in GPi neuronal encoding might contribute to slow down movement in Parkinsonian monkeys

Although widely investigated, the exact relationship between changes in basal ganglia neuronal activity and parkinsonian symptoms has not yet been deciphered. It has been proposed that bradykinesia (motor slowness) is related either to a modification of the activity of the globus pallidus internalis (GPi), the main output structure, or to a loss of spatial selectivity of the extrapyramidal motor system. Here we investigate the relationship between movement initiation and GPi activity in parkinsonian non‐human primates. We compare neuronal encoding of movement in the normal and pathological conditions. After dopamine depletion, we observe an increased number of neurons responding to movement, with a less specific somato‐sensory receptive field and a disruption of the selection mechanism. Moreover, the temporal order of the response of GPi neurons in parkinsonian animals is reversed. Indeed, whereas muscle activity and movement are delayed in parkinsonian animals, GPi neuronal responses to movement occur earlier and are prolonged, compared with normal conditions. Parkinsonian bradykinesia could thus result from an impairment of both temporal and spatial specificity of the GPi response to movement.
History, literature, and philosophy: A systematic review of positive functioning

ABSTRACT The humanities are instrumental to human development and happiness and are an integral part of our lives. However, a lack of empirical research limits our current understanding of the role the humanities play in the well-being of individuals, communities, and societies. Through a systematic search of the literature, we identify and review empirical studies that investigate whether engagement with history, literature, and philosophy influences individual’s well-being (i.e. psychological well-being, subjective well-being, and virtues). The results suggest that studies investigating such influences are limited and mainly conducted in pedagogical settings. At the same time, these studies provide initial evidence for the positive effects of engagement in the humanities on individual well-being. Through this review, we identify gaps in the literature and provide recommendations for future research.
Evolution of the quasi-periodic oscillation frequency in GRO J1655-40 - Implications for accretion disk dynamics

Context. Low and intermediate frequency quasi-periodic oscillations (QPOs) are thought to be due to oscillations of Comptonizing regions or hot blobs embedded in Keplerian disks. Any movement of these perturbations is expected systematically to change the QPO frequency. Aims. Our goal is to find systems where such a systematic drifts have been observed. We also try to find the real cause of such drifts and whether they shed some light on the accretion disk dynamics. Methods. Using archival data of the recent outburst of GRO J1655-40, we report the presence of such systematic drifts not only during the rising phase from the 25th of February 2005 to the 12th March 2005, when the QPO frequency monotonically increased from 82 mHz to 17.78 Hz but also in the decline phase from the 15th September 2005 to the 5th of October 2005, when the QPO frequency decreased from 13.14 Hz to 34 mHz. Results. We fitted the frequency drifts with the propagatory oscillating shock solution. In the shock-oscillation solution, the frequency is inversely proportional to the infall time scale from the shock location. We obtained the shock location and strength through such a fit. Conclusions. The astonishing smoothness of the variation of the QPO frequency over a period of weeks directly supports the view that it may due to the drift of an oscillating shock rather than the movements of a blob inside a differentially rotating disk.
Living single: A phenomenological study of a group of South African single women

Worldwide, societies continue to privilege the ideology of couplehood to the detriment of other relationship states, like singlehood, that are steadily increasing in number. Furthermore, according to developmental psychology theory, the formation of a committed romantic relationship is viewed as an important psychosocial developmental task in adulthood. It is therefore not surprising that women’s experience of being single has generally been neglected by psychological theory and research. Situated in a feminist-phenomenological perspective, this study explored the experiences of tertiary-educated, child-free, never-married, White, South African women between the ages of 30 and 40. Giorgi’s descriptive-phenomenological method was used to analyse the individual interview data. In this article, we discuss four of the prominent themes that best reflect the collective views and multi-faceted experiences of the participants: singlehood brings both freedom and loneliness; career as both fulfilment and singlehood coping mechanism; committed partners as sources of both restriction and connection; and hoping for a committed relationship. We highlight how the notion of a committed sexual relationship as the ultimate relationship that provides effortless connectedness and companionship underpins all of these themes. We argue that alternative discourses and mechanisms of connection that accommodate people who live as single adults, should be fostered.
Influence of Environmental Variables on Benthic Macroinvertebrate Communities in a Shallow Eutrophic Lowland Lake (Ge Lake, China)

Shallow lowland lakes are critical components of the water cycle, providing an essential service function. However, the impacts of microcystin from phytoplankton communities on benthic macroinvertebrate community diversity and structure have seldom been investigated. During 2008-2012, the impacts of water environmental variables on the diversity of macrobenthic communities, including water temperature, pH, dissolved oxygen, transparency, conductivity, the permanganate index, Chlorophyll a , total phosphorus, total nitrogen, and microcystin-LR (L for leucine and R for arginine), were measured in a typical shallow lowland lake, Ge Lake. The results of the present study demonstrated that there were 31 benthic macroinvertebrate taxa in Ge Lake, including 7 oligochaetes, 7 mollusca, 14 chironomids, and 3 other taxa. Among the macrobenthic taxa in the benthic community, opportunistic taxa such as Limnodrilus hoffmeisteri are present and can occur at greater densities in disturbed habitats. However, a significant reduction/disappearance of sensitive and clean taxa was observed among the benthic macroinvertebrates. Water temperature, dissolved oxygen, conductivity, ammonia nitrogen, transparency and total phosphorus were the main environmental variables influencing macrobenthic community structure, while water temperature, conductivity, ammonia nitrogen, Chlorophyll a , the permanganate index, total phosphorus and total nitrogen were the main factors that influenced macrobenthic community diversity indices (the numbers of taxa, Shannon’s diversity index, Margalef’s richness index, and Pielou’s evenness index). Our results underscore the severity of the effects of human activity on Ge Lake and strongly suggest that restoring the benthic invertebrate community to previous conditions would require the control and reduction of environmental pollutants and nutrients in Ge Lake.
Sustained Elevation of Systemic Oxidative Stress and Inflammation in Exacerbation and Remission of Asthma

Oxidative stress has been implicated in the pathogenesis of asthma. We aimed at investigating the biomarkers of oxidative stress, inflammation, and tissue damage in patients with asthma in acute exacerbation and remission. We recruited 18 asthmatics admitted to hospital with acute exacerbation and 18 healthy nonsmoking controls matched for age. We evaluated plasma levels of 8-isoprostane, C-reactive protein (CRP) and total matrix metalloproteinase- (MMP-) 9 by ELISA, and MMP-9 activity by zymographic analysis. Plasma levels of 8-isoprostane and CRP were significantly elevated in acute exacerbation and decreased in remission but remained significantly higher compared to healthy controls. The activities of pro-MMP-9 were also significantly higher in acute exacerbation and decreased in remission but remained significantly higher compared to healthy controls in parallel to plasma levels of total MMP-9. These data suggest that overproduction of MMP-9 along with highly elevated levels of oxidative stress and inflammation is implicated in asthma exacerbation and that measurements of these biomarkers can be a valid index in its management.
C-reactive protein mediates the effect of apolipoprotein E on cytomegalovirus infection.

BACKGROUND Although the apolipoprotein (APOE)-epsilon4 allele has been shown to determine the outcome of several infections, its relationship with cytomegalovirus (CMV) has not been explored. We examine whether APOE determines CMV and herpes simplex virus type 1 (HSV-1) antibody levels and assess whether C-reactive protein (CRP) mediates any observed relationships. METHODS We conducted a cross-sectional analysis of a randomly selected subset (n = 1561/1789) of participants aged 60-101 in the Sacramento Area Latino Study on Aging. Blood samples were tested for APOE genotype, CRP, and immunoglobulin G antibodies to CMV and HSV-1. Multivariate logistic regression was used to examine the association between epsilon4 and CMV and HSV antibody levels. We also assessed whether CRP mediates the effects of any observed associations between epsilon4 and viral antibody levels. RESULTS CMV antibody and CRP levels varied significantly by APOE genotype. The association between CRP and CMV antibody was strengthened in the presence of epsilon4. In contrast, this effect was not observed in HSV-1. We found that APOE-epsilon4 carriers had significantly lower levels of CRP yet significantly higher levels of CMV antibodies, suggesting a mediating pathway. CONCLUSIONS APOE-epsilon4 carriers may experience immunological aberrations that lead to lower levels of CRP and correspondingly higher CMV antibody levels.
Assessment of implicit personality self-concept using the implicit association test (IAT): concurrent assessment of anxiousness and angriness.

This study explored the psychometric properties of the Implicit Association Test (IAT) when it is employed for the assessment of two personality traits within one sample. The sequence of an anxiousness and an angriness IAT was counterbalanced across 100 participants and the IATs' predictive validity for anxious versus angry behaviour after emotion inductions was examined and compared to direct self-report measures. The anxiousness IAT added incremental validity over direct measures for the prediction of anxious behaviour. The angriness IAT was affected by an order effect. When the angriness IAT was completed after the anxiousness IAT both tests correlated with r=. 46 whereas they were not significantly correlated when the angriness IAT was completed first. Direct anxiousness and angriness measures were uncorrelated. Implications for the assessment of multiple implicit personality self-concept dimensions are discussed.
Investigating the Empirical Relation and Importance of Perceived Usefulness, Perceived Ease of Use and Intention to Use Online Information Resources for Evidence Based Medicine

This study explores the empirical relationship and importance of perceived usefulness, perceived ease of use and intention to use online information resources for Evidence-based Medicine (EBM). Although a significant literature is available that investigates the effect of various factors on intention to use digital information sources to practice EBM in developed countries. However, literature is a lacking in exploring the intention to practice EBM by physicians in developing countries like Pakistan. This is the motivation behind this study. This research is a cross sectional quantitative survey study (N=352). Based on related literature a questionnaire was developed. Selected participant sample of the survey is those physicians, who were in clinical practice and were having the knowledge of EBM. Structural equation modelling technique (SEM) with the Analysis of Moment Structures software (AMOS) is used for data analysis. The findings showed the significance and causal linkage between perceived usefulness, perceived ease of use and intention to use online information resources for EBM. Perceived usefulness is found as a strong predictor in acceptance and behavioral intention as compared to the perceived ease of use.
Antioxidant Activity of Inulin and Its Role in the Prevention of Human Colonic Muscle Cell Impairment Induced by Lipopolysaccharide Mucosal Exposure

Background Fructans, such as inulin, are dietary fibers which stimulate gastro-intestinal (GI) function acting as prebiotics. Lipopolysaccharide (LPS) impairs GI motility, through production of reactive oxygen species. The antioxidant activity of various fructans was tested and the protective effect of inulin on colonic smooth muscle cell (SMC) impairment, induced by exposure of human mucosa to LPS, was assessed in an ex vivo experimental model. Methods The antioxidant capacity of fructans was measured in an in vitro system that simulates cooking and digestion processes. Human colonic mucosa and submucosa, obtained from disease-free margins of resected segments for cancer, were sealed between two chambers, with the mucosal side facing upwards with Krebs solution with or without purified LPS from a pathogenic strain of Escherichia coli (O111:B4) and inulin (Frutafit IQ), and the submucosal side facing downwards into Krebs solution. The solutions on the submucosal side were collected following mucosal exposure to Krebs in the absence (N-undernatant) or presence of LPS (LPS-undernatant) or LPS+inulin (LPS+INU-undernatant). Undernatants were tested for their antioxidant activity and the effects on SMCs contractility. Inulin protective effects on mucosa and submucosa layers were assessed measuring the protein oxidation level in the experimental conditions analyzed. Results Antioxidant activity of inulin, which was significantly higher compared to simple sugars, remained unaltered despite cooking and digestion processes. Inulin protected the mucosal and submucosal layers against protein oxidation. Following exposure to LPS-undernatant, a significant decrease in maximal acetylcholine (Ach)-induced contraction was observed when compared to the contraction induced in cells incubated with the N-undernatant (4±1% vs 25±5% respectively, P<0.005) and this effect was completely prevented by pre-incubation of LPS with Inulin (35±5%). Conclusions Inulin protects the human colon mucosa from LPS-induced damage and this effect appears to be related to the protective effect of inulin against LPS-induced oxidative stress.
Detecting Deoxyhemoglobin in Spinal Cord Vasculature of the Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis Using Susceptibility MRI and Hyperoxygenation

Susceptibility-weighted imaging (SWI) detects hypointensities due to iron deposition and deoxyhemoglobin. Previously it was shown that SWI detects hypointensities in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS), most of which are due to intravascular deoxyhemoglobin, with a small proportion being due to iron deposition in the central nervous system parenchyma and demyelination. However, animals had to be sacrificed to differentiate these two types of lesions which is impractical for time course studies or for human application. Here, we proposed altering the inspired oxygen concentration during imaging to identify deoxyhemoglobin-based hypointensities in vivo. SWI was performed on lumbar spinal cords of naive control and EAE mice using 30% O2 then 100% O2. Some mice were imaged using 30% O2, 100% O2 and after perfusion. Most SWI-visible hypointensities seen with 30% O2 changed in appearance upon administration of 100% O2, and were not visible after perfusion. That hypointensities changed with hyperoxygenation indicates that they were caused by deoxyhemoglobin. We show that increasing the inspired oxygen concentration identifies deoxyhemoglobin-based hypointensities in vivo. This could be applied in future studies to investigate the contribution of vascular-based hypointensities with SWI in EAE and MS over time.
Digital Transcriptome Analysis of Putative Sex-Determination Genes in Papaya (Carica papaya)

Papaya (Carica papaya) is a trioecious plant species that has male, female and hermaphrodite flowers on different plants. The primitive sex chromosomes genetically determine the sex of the papaya. Although draft sequences of the papaya genome are already available, the genes for sex determination have not been identified, likely due to the complicated structure of its sex-chromosome sequences. To identify the candidate genes for sex determination, we conducted a transcriptome analysis of flower samples from male, female and hermaphrodite plants using high-throughput SuperSAGE for digital gene expression analysis. Among the short sequence tags obtained from the transcripts, 312 unique tags were specifically mapped to the primitive sex chromosome (X or Yh) sequences. An annotation analysis revealed that retroelements are the most abundant sequences observed in the genes corresponding to these tags. The majority of tags on the sex chromosomes were located on the X chromosome, and only 30 tags were commonly mapped to both the X and Yh chromosome, implying a loss of many genes on the Yh chromosome. Nevertheless, candidate Yh chromosome-specific female determination genes, including a MADS-box gene, were identified. Information on these sex chromosome-specific expressed genes will help elucidating sex determination in the papaya.
Lorentz Harmonics, Squeeze Harmonics and Their Physical Applications

Among the symmetries in physics, the rotation symmetry is most familiar to us. It is known that the spherical harmonics serve useful purposes when the world is rotated. Squeeze transformations are also becoming more prominent in physics, particularly in optical sciences and in high-energy physics. As can be seen from Dirac’s light-cone coordinate system, Lorentz boosts are squeeze transformations. Thus the squeeze transformation is one of the fundamental transformations in Einstein’s Lorentz-covariant world. It is possible to define a complete set of orthonormal functions defined for one Lorentz frame. It is shown that the same set can be used for other Lorentz frames. Transformation properties are discussed. Physical applications are discussed in both optics and high-energy physics. It is shown that the Lorentz harmonics provide the mathematical basis for squeezed states of light. It is shown also that the same set of harmonics can be used for understanding Lorentz-boosted hadrons in high-energy physics. It is thus possible to transmit physics from one branch of physics to the other branch using the mathematical basis common to them.
Memory for the future : implications of implicit cognitions in depression

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The UCLA Longitudinal Study of Neurocognitive Outcomes Following Mild Pediatric Traumatic Brain Injury

Abstract Comprehensive reviews of neurocognitive outcomes following mild, uncomplicated traumatic brain injury (TBI) in children have shown minimal effects on neurocognition, especially in methodologically rigorous studies. In this study, we report longitudinal (1, 6, and 12 months post injury) results in four domains of neurocognitive functioning in a large sample of children with mild TBI (n = 124, ages 8–17 at injury) relative to two demographically matched control groups (other injury: n = 94 and non-injury: n = 106). After accounting for age and parental education, significant main effects of group were observed on 7 of the 10 neurocognitive tests. However, these differences were not unique to the TBI sample but were found between both the TBI and other injury groups relative to the non-injured group, suggesting a general injury effect. Effects were primarily within the domains measuring memory, psychomotor processing speed, and language. This is the largest longitudinal study to date of neurocognitive outcomes at discrete time points in pediatric mild TBI. When controlling for pre-injury factors, there is no evidence of long-term neurocognitive impairment in this group relative to another injury control group. The importance of longitudinal analyses and use of appropriate control groups are discussed in the context of evaluating the effects of mild TBI on cognition. (JINS, 2011, 17, 886–895)