Miracle-dz/UniFAR-FTUs huggingface dataset:
Multimodal emotion perception after anterior temporal lobectomy (ATL)

In the context of emotion information processing, several studies have demonstrated the involvement of the amygdala in emotion perception, for unimodal and multimodal stimuli. However, it seems that not only the amygdala, but several regions around it, may also play a major role in multimodal emotional integration. In order to investigate the contribution of these regions to multimodal emotion perception, five patients who had undergone unilateral anterior temporal lobe resection were exposed to both unimodal (vocal or visual) and audiovisual emotional and neutral stimuli. In a classic paradigm, participants were asked to rate the emotional intensity of angry, fearful, joyful, and neutral stimuli on visual analog scales. Compared with matched controls, patients exhibited impaired categorization of joyful expressions, whether the stimuli were auditory, visual, or audiovisual. Patients confused joyful faces with neutral faces, and joyful prosody with surprise. In the case of fear, unlike matched controls, patients provided lower intensity ratings for visual stimuli than for vocal and audiovisual ones. Fearful faces were frequently confused with surprised ones. When we controlled for lesion size, we no longer observed any overall difference between patients and controls in their ratings of emotional intensity on the target scales. Lesion size had the greatest effect on intensity perceptions and accuracy in the visual modality, irrespective of the type of emotion. These new findings suggest that a damaged amygdala, or a disrupted bundle between the amygdala and the ventral part of the occipital lobe, has a greater impact on emotion perception in the visual modality than it does in either the vocal or audiovisual one. We can surmise that patients are able to use the auditory information contained in multimodal stimuli to compensate for difficulty processing visually conveyed emotion.
Finding the Right t-PA Dose for Asians with Acute Ischemic Stroke.

The efficacy of intravenous thrombolysis with tissue plasminogen activator (t-PA) for improving outcomes in patients with acute ischemic stroke has driven the infrastructure development for acute stroke care delivery in the United States, Europe, and Australia for the past 20 years. The early implementation was slow and cautious; 60% of U.S. neurologists cited safety concerns regarding the risk of symptomatic intracerebral hemorrhage, but only 9% cited cost as a barrier.1 That may change, because the average cost of a standard dose of alteplase increased by 111%, from $3,050 to $6,430, during the past decade.2 In Asia, where 50% of the .
Fading renal hyperfiltration in children following liver transplantation

Abstract: In a prospective longitudinal study, we investigated the renal function (RF) of 23 children before and after orthotopic liver transplantation (OLT). The aim was to assess both the outcome of pretransplant hyperfiltration and the clinical nephrotoxic effects of cyclosporin A (CsA); children with decreased RF prior to OLT were therefore excluded. The RF study of the 13 remaining patients included glomerular filtration rate (GFR) and effective renal plasma flow (RPF) measured by inulin (Cin: mL/min/1.73 m2) and para‐amino hippurate (Cpah: mL/min/1.73 m2) clearances, respectively. Hyperfiltration prior to OLT was observed in six children, i.e. Cin > 170 [range 172–230] and Cpah > 800 [808–1133]. A significant decrease in RF was noted as soon as 6 months after OLT: Cin (mean±SD) = 107 ± 23 vs. 158 ± 46 (p<0.003); Cpah = 583 ± 119 vs. 791 ± 243 (p<0.004). This was due to loss of hyperfiltration in the six children, as there was no significant difference in RF before and 6 months after OLT in the other seven children. With a 36‐month follow‐up, there was no correlation between CsA trough blood level and RF. In conclusion, following OLT, RF underwent early changes owing to loss of prior hyperfiltration in children without impaired RF before OLT. In addition, no evidence of CsA nephrotoxicity was found and RF remained stable during follow‐up.
Improving position estimation on RFID tag floor localization using RFID reader transmission power control

Localization of indoor mobile robot is one of main issues on service robot area. Various sensor systems like odometry, INS, ultra sonic, laser lange finder (LRF), RF range systems such as UWB and chirp spread-spectrum (CSS), and vision have been applied to solve localization problem. RFID system can be a solution due to the low cost and scalability. A RFID system used to localize mobile robot in distributed tags on the floor is called RFID Tag floor localization system. RFID tag floor localization system generally uses fixed tag recognition range or probability model. In this paper, RFID reader transmission power control is introduced to change the tag recognition range to get more information about distances of tags. Using RFID power control, the performance of a position estimation was improved in simulation. The experimental results also showed improvement.
Structural and electronic properties of ni-doped zno in zinc-blende phase: a DFT investigations

In the present work investigations of structural and electronic properties of nickel doped ZnO in zinc-blende phase have been done in the framework of density functional theory. In doping process 25% cations (Zn atoms) have been replaced by Ni atoms. Wu-Cohen parameterized Generalized Gradient Approximation (GGA-WC) is used for exchange and correlation energy functional treatment. Our calculations for structural properties reveal a reduction in lattice constant with Ni doping. Whereas the spin polarized electronic structures show metallic behavior of ZnO in the presence of Ni impurity atoms for both up and down spin configuration. Moreover we present calculated density of states to understand the effect of Ni doping on ZnO.
Liver injury from nonsteroidal anti‐inflammatory drugs in the United States

Nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly used and have been associated with hepatotoxicity. Studies of liver injury from NSAIDs have been retrospective and prospective data are lacking. The aim was to report the features and outcomes of the subjects with severe drug‐induced liver injury from NSAIDS.
Mining generalized query patterns from web logs

User logs of a popular search engine keep track of user activities including user queries, user click-through from the returned list, and user browsing behaviors. Knowledge about user queries discovered from user logs can improve the performance of the search engine. We propose a data-mining approach that produces generalized query patterns or templates from the raw user logs of a popular commercial knowledge-based search engine that is currently in use. Our simulation shows that such templates can improve search engine's speed and precision, and can cover queries not asked previously. The templates are also comprehensible so web editors can easily discover topics in which most users are interested.
The genetic structure of Australasian green turtles (Chelonia mydas): exploring the geographical scale of genetic exchange

Ecological and genetic studies of marine turtles generally support the hypothesis of natal homing, but leave open the question of the geographical scale of genetic exchange and the capacity of turtles to shift breeding sites. Here we combine analyses of mitochondrial DNA (mtDNA) variation and recapture data to assess the geographical scale of individual breeding populations and the distribution of such populations through Australasia. We conducted multiscale assessments of mtDNA variation among 714 samples from 27 green turtle rookeries and of adult female dispersal among nesting sites in eastern Australia. Many of these rookeries are on shelves that were flooded by rising sea levels less than 10 000 years (c. 450 generations) ago. Analyses of sequence variation among the mtDNA control region revealed 25 haplotypes, and their frequency distributions indicated 17 genetically distinct breeding stocks (Management Units) consisting either of individual rookeries or groups of rookeries in general that are separated by more than 500 km. The population structure inferred from mtDNA was consistent with the scale of movements observed in long‐term mark–recapture studies of east Australian rookeries. Phylogenetic analysis of the haplotypes revealed five clades with significant partitioning of sequence diversity (Φ = 68.4) between Pacific Ocean and Southeast Asian/Indian Ocean rookeries. Isolation by distance was indicated for rookeries separated by up to 2000 km but explained only 12% of the genetic structure. The emerging general picture is one of dynamic population structure influenced by the capacity of females to relocate among proximal breeding sites, although this may be conditional on large population sizes as existed historically across this region.
Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial.

PURPOSE The optimal timing of surgery after preoperative radiotherapy in rectal cancer is unknown. The aim of this trial was to evaluate the role of the interval between preoperative radiotherapy and surgery. PATIENTS AND METHODS Patients with rectal carcinoma accessible to rectal digital examination, staged T2 to T3, NX, M0, were randomized before radiotherapy (39 Gy in 13 fractions) into two groups: in the short interval (SI) group, surgery had to be performed within 2 weeks after completion of radiation therapy, compared with 6 to 8 weeks in the long interval (LI) group. Between 1991 and 1995, 201 patients were enrolled onto the study. RESULTS A long interval between preoperative radiotherapy and surgery was associated with a significantly better clinical tumor response (53. 1% in the SI group v 71.7% in the LI group, P =.007) and pathologic downstaging (10.3% in the SI group v 26% in the LI group, P =.005). At a median follow-up of 33 months, there were no differences in morbidity, local relapse, and short-term survival between the two groups. Sphincter-preserving surgery was performed in 76% of cases in the LI group versus 68% in the SI group (P = 0.27). CONCLUSION A long interval between preoperative irradiation and surgery provides increased tumor downstaging with no detrimental effect on toxicity and early clinical results. When sphincter preservation is questionable, a long interval may increase the chance of a successful sphincter-saving surgery.
Reliable measures of synt a ctic and lexical complexity : The case of Iris Murdoch

Quantitative measures of the syntactic and lexical complexity of natural language text – such as type-token ratio (TTR), Yule’s K (1944) or Yngve depth (Yngve, 1960) – play a central role in stylometric analysis. They have been used to investigate stylometric differences between writers and settle questions of disputed authorship (Stamatatos, 2009), to explore the characteristics of translated texts (Volansky, Ordan, & Wintner, 2015), to identify determinants of style in scientific writing (Bergsma, Post, & Yarowsky, 2012), to study diachronic changes in grammar (Bentz, Kiela, Hill, & Buttery, 2014), to assess the readability and difficulty level of a text (Graesser, McNamara, Louwerse, & Cai, 2004; Collins-Thompson, 2014), and as a feature in the multivariate analysis of linguistic variation (Biber, 1988; Diwersy, Evert, & Neumann, 2014). In particular, several recent studies (Garrard, Maloney, Hodges, & Patterson, 2005; Pakhomov, Chacon, Wicklund, & Gundel, 2011; Le, Lancashire, Hirst, & Jokel, 2011) attempt to detect early symptoms of dementia in the last novels written by the British author Iris Murdoch, who was diagnosed with Alzheimer’s disease in 1997. These studies focus primarily on quantitative complexity measures, based on the assumption that beginning dementia reduces either the lexical or the syntactic complexity of a patient’s writing. Results were inconclusive: while the first two studies obsereved a promising decline of complexity in Murdoch’s last novel Jackson’s Dilemma published in 1995,1 Le et al. (2011) analyzed a larger sample of Murdoch’s writings and found that most of the quantitative measures did not to show any clear effects. In particular, they rejected the hypothesis of a decline in syntactic complexity. Like most work in stylometry, all three studies fail to take the sampling distributions of complexity measures into account. As a result, they are prone to over-interpreting observed differences that may well be explained by random variation. Only Le et al. (2011) apply significance tests, but they test for a linear trend in complexity across the span of Murdoch’s writing career, which would not be consistent with the typical development of Alzheimer’s disease. In this paper, we propose a novel methodology for the computation of reliable confidence intervals and significance tests for measures of linguistic complexity, inspired by ideas from bootstrapping and cross-validation. As an illustration, we apply the new method to the case of Iris Murdoch, showing that most of the differences observed in previous work are not signficant and can indeed be accounted for by sampling variation.
Effect of thermal cycling on micro-tensile bond strength of composite restorations bonded with multimode adhesive

Objective: The purpose of this in vitro study was to evaluate the effect of thermal cycling on the micro-tensile bond strength (Mtbs) of multimode adhesive agents. Materials and methods: Eight freshly extracted caries-free human third molars were used. The flat dentin surfaces were prepared and polished with 600-grit SiC abrasive paper for standard smear layer formation. The teeth were restored using Single Bond Universal Adhesive [(total etch (G1, G2)/self etch (G3, G4)] + Filtek Z550 and All-Bond Universal Adhesive [(total etch (G5, G6)/self etch (G7, G8)] + Aelite all-purpose. The specimens in groups G1, G3, G5, and G7 were subjected to thermal cycling (1000 cycles at 5–55 °C, for a 30 s dwell time), while the specimens in other groups were not exposed to an aging procedure. The Mtbs test was determined in all procedures. Data were submitted to three-way ANOVA and post hoc tests. The significance level was set at = 0.05. Results: Group five was highly affected by the thermal cycling following the total etch procedure, while group one was not significantly affected. Group seven was highly affected by thermal cycling, while group three was not significantly affected after the self etch procedure. Group eight exhibited a higher mean Mtbs value after the thermal cycling procedure. Conclusion: The bond strength of multimode (universal) adhesives was found to be material dependent. The total etch procedure showed a higher Mtbs value than the self etch procedure.
Children's fear and behavior in private pediatric dentistry practices.

PURPOSE This study assessed the proportion of children with dental fear, the proportion of children with negative behavior and the relationship of children's dental fear and children's negative behavior in private pediatric dentistry practices in western Washington state. METHODS A total of 421 children seen in 21 private pediatric dentistry practices in western Washington State participated. The average age of the children was 6.8+/-2.8 years (range=0.8-12.8 years). An average of 21 children were studied per practice (range=7-25 children). Dental fear was measured using the parents' version of the Dental Subscale of the Child Fear Survey Schedule (CFS). Behavior of the child during treatment was rated using the Frankl scale. Additional data were collected regarding the child's previous experiences and parental fear. RESULTS The children's average item score on the 15-item CFS was 2+/-0.7, corresponding to a total score of 29.6 out of 75, where 75 indicates maximum fear. The proportion of children with dental fear, defined as an average item score of > or = 2.5 (corresponding to a total score of > or = 38), was 20% (85/421, 95% CI=16.3, 24%). The proportion of children who displayed negative behavior during treatment was 21% (95% CI=17.5, 24%). A prevalence ratio of 2.4 was calculated to describe the relationship between children's behavior during treatment and children's dental fear prior to dental treatment. Multivariate logistical regression analysis showed children with dental fear, younger children, and children exposed to treatment involving local anesthesia have higher odds of displaying negative behavior. CONCLUSIONS The proportion of children with dental fear in private pediatric dentistry practices was 20%, and the proportion of children with negative behavior during treatment was 21%. Children with negative behavior had greater odds of having dental fear and children with dental fear had greater odds of having negative behavior. Screening for dental fear may allow pediatric dentists to prepare children more adequately for positive treatment experiences.
Identification of Recently Handled Materials by Analysis of Latent Human Fingerprints Using Infrared Spectromicroscopy

Analysis of fingerprints has predominantly focused on matching the pattern of ridges to a specific person as a form of identification. The present work focuses on identifying extrinsic materials that are left within a person's fingerprint after recent handling of such materials. Specifically, we employed infrared spectromicroscopy to locate and positively identify microscopic particles from a mixture of common materials in the latent human fingerprints of volunteer subjects. We were able to find and correctly identify all test substances based on their unique infrared spectral signatures. Spectral imaging is demonstrated as a method for automating recognition of specific substances in a fingerprint. We also demonstrate the use of attenuated total reflectance (ATR) and synchrotron-based infrared spectromicroscopy for obtaining high-quality spectra from particles that were too thick or too small, respectively, for reflection/absorption measurements. We believe the application of this rapid, nondestructive analytical technique to the forensic study of latent human fingerprints has the potential to add a new layer of information available to investigators. Using fingerprints to not only identify who was present at a crime scene, but also to link who was handling key materials, will be a powerful investigative tool.
A self-regulatory approach to understanding boredom proneness

ABSTRACT We investigated the relationship between self-regulation and two types of boredom proneness (perceived lack of internal stimulation, perceived lack of external stimulation) using a variety of measures of self-regulation. These included a general measure of self-control, measures of both regulatory focus (i.e., promotion or a sensitivity to gains/non-gains vs. prevention or a sensitivity to losses/non-losses) and regulatory mode (i.e., assessment or the tendency to compare means and goals vs. locomotion or the tendency to initiate and maintain commitment to action), and measures of cognitive flexibility (i.e., a perceived sense of control and the tendency to seek alternative solutions). Results identified a unique set of factors related to each boredom proneness component. Trait self-control and prevention focus were associated with lower boredom propensity due to a lack of external stimulation. Locomotion and the tendency to seek alternatives were associated with lower boredom propensity due to a lack of internal stimulation. These findings suggest that effective goal pursuit is associated with reduced likelihood of experiencing boredom.
Myocardial Contractile Function and Myofibrillar Adenosine Triphosphatase Activity in Chemically Sympathectomized Rats

The contractile properties and contractile protein enzymatic activity of skeletal muscle can be altered by neural influences. To determine whether similar influences apply to cardiac muscle, adult rats were chemically sympathectomized by intravenous injection of 6-hydroxydopamine (6-OHDA). After 2 weeks of treatment, rats were anesthetized and an index of myocardial contractility (max dP/dt) was measured in situ. Max dP/dt was depressed in 6-OHDA-treated rats [4560 ± 420 (mean ± se) mm Hg/sec] when compared to controls (6710 ± 580 mm Hg/sec). Sympatbectomy was verified by reduced hemodynamic responsiveness to tyramine injections. After functional measurements bad been completed, the heart was excised. Myofibrils were prepared from left rentricnlar tissue and analyzed for ATPase activity. Myofibrillar protein yield averaged 38 ± 2 mg/g in controls and was not significantly different in 6-OHDA rats. Myofibrillar ATPase activity was 0314 ± 0.014 &mgr;mol P,/mg per min in controls. Enzyme activity was significantly reduced to (1.230 ± 0.020 &mgr;mol P1/mg per min in 6-OHDA rats. The results demonstrate that a chronic reduction in sympathetic stimulation to the heart results in a depression of an index of myocardial contractile function which is accompanied by reduced myofibrillar ATPase activity. Acute (16–18 hours) chemical sympathectomy depressed the contractile function index without altering ATPase activity. Bilateral adrenalectomy produced no further decrement in myofibrillar ATPase activity in chronically (2 weeks) sympathectomized rats. Therefore, it appears that the changes in contractile protein enzymatic properties are mediated by sympathetic neural influences and may involve the synthesis of new contractile protein(s) with altered enzymatic properties.
Analysis of template update strategies for keystroke dynamics

Keystroke dynamics is a behavioral biometrics showing a degradation of performance when used over time. This is due to the fact that the user improves his/her way of typing while using the system, therefore the test samples may be different from the initial template computed at an earlier stage. One way to bypass this problem is to use template update mechanisms. We propose in this work, new semi-supervised update mechanisms, inspired from known supervised ones. These schemes rely on the choice of two thresholds (an acceptance threshold and an update threshold) which are fixed manually depending on the performance of the system and the level of tolerance in possible inclusion of impostor data in the update template. We also propose a new evaluation scheme for update mechanisms, taking into account performance evolution over several time-sessions. Our results show an improvement of 50% in the supervised scheme and of 45% in the semi-supervised one with a configuration of the parameters chosen so that we do not accept many erroneous data.