Miracle-dz/UniFAR-FTUs huggingface dataset:
The Disk and Extraplanar Regions of NGC 2403

Wide-field images obtained with WIRCam and MegaCam on the Canada-France-Hawaii Telescope are used to probe the spatial distribution of young stars in the Sc galaxy NGC 2403. Bright main-sequence stars and blue supergiants are detected out to projected galactocentric distances of ~14 kpc (~7 disk scale lengths), as measured along the major axis. The star formation rate (SFR) in the disk of NGC 2403 during the past 10 Myr has been 1 M☉ yr-1 based on the number of bright main-sequence stars. The radially averaged number density of red supergiants (RSGs) per unit r-band surface brightness is constant throughout the disk, indicating that (1) RSGs follow the integrated r-band light, and (2) the SFR per unit mass has been constant with radius when averaged over timescales of a few tens of millions of years. The mean color of RSGs varies with galactocentric distance, suggesting that there is a metallicity gradient among recently formed stars. A comparison of the radially averaged number density of bright main-sequence stars also indicates that the SFR per unit stellar mass in NGC 2403 has been ~3 times higher than in NGC 247 during recent epochs, and this is in rough agreement with what would be predicted from the far-infrared fluxes of these galaxies. Finally, the data are used to investigate the extraplanar regions of NGC 2403. A population of M giants with peak brightness MK = -8 is detected at projected distances between 12 and 14 kpc above the disk plane, and six new globular cluster candidates are identified.
Graphic Violence as Moral Motivator: The Effects of Graphically Violent Content in News

Common wisdom holds that graphic media violence leads to antisocial outcomes. This common wisdom is reflected in the Society for Professional Journalists’ Code of Ethics. However, theory and research regarding moral emotions’ ability to increase moral sensitivity suggests that this type of negative content may be capable of yielding prosocial responses. This article describes this logic and tests its predictions in two experimental studies utilizing news footage of a mass execution conducted by the Islamic State in Iraq and Syria (ISIS). Results corroborate claims that graphic media violence can serve as a moral motivator. Higher levels of graphic violence led to stronger anger and disgust responses, which in turn predicted higher levels of (a) moral sensitivity, (b) desires for anti-ISIS interventions (including military and humanitarian efforts), and (c) eudaimonic motivations (i.e., seeking meaning in life). Important to note, no increases in negative attitudes toward Arab Muslims were observed. Theoretical implications are discussed.
Toward 1-mGal accuracy in global marine gravity from CryoSat-2, Envisat, and Jason-1

More than 60% of the Earth's land and shallow marine areas are covered by > 2 km of sediments and sedimentary rocks, with the thickest accumulations on rifted continental margins (Figure 1). Free-air marine gravity anomalies derived from Geosat and ERS-1 satellite altimetry (Fairhead et al., 2001; Sandwell and Smith, 2009; Andersen et al., 2009) outline most of these major basins with remarkable precision. Moreover, gravity and bathymetry data derived from altimetry are used to identify current and paleo-submarine canyons, faults, and local recent uplifts. These geomorphic features provide clues to where to look for large deposits of sediments. While current altimeter data delineate large offshore basins and major structures, they do not resolve some of the smaller geomorphic features and basins (Yale et al., 1998; Fairhead et al., 2001). Improved accuracy and resolution is desirable: to facilitate comparisons between continental margins; as an exploration tool and to permit extrapolation of known structu.
IDENTIFYING LUMINOUS ACTIVE GALACTIC NUCLEI IN DEEP SURVEYS: REVISED IRAC SELECTION CRITERIA

Spitzer/IRAC selection is a powerful tool for identifying luminous active galactic nuclei (AGNs). For deep IRAC data, however, the AGN selection wedges currently in use are heavily contaminated by star-forming galaxies, especially at high redshift. Using the large samples of luminous AGNs and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high-redshift star-forming galaxies selected via the BzK, distant red galaxy, Lyman-break galaxy, and submillimeter galaxy criteria. At QSO luminosities of log L2–10 keV(erg s−1) ⩾44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 38% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 52% in regions with Chandra exposures of 50–160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates leads to a hard X-ray signal indicative of heavily obscured to mildly Compton-thick obscuration (log NH (cm−2) = 23.5 ± 0.4). While IRAC selection recovers a substantial fraction of luminous unobscured and obscured AGNs, it is incomplete to low-luminosity and host-dominated AGNs.
Understanding adolescents’ mental health and academic achievement: Does physical fitness matter?

Despite consensus that physical fitness (PF) plays an important role in promoting mental health and academic achievement, little is known regarding the mechanisms by which this effect works. Blair, Cheng, and Holder (2001) proposed a conceptual model to identify the behavioral mechanism of health outcomes, in which both health-related PF and skill-related PF were identified as the direct determinants of health outcomes. Guided by Blair and colleagues’ model, the primary purpose of this study was to examine the association between health-related PF, skill-related PF, depression and academic achievement among adolescents. The second purpose was to investigate whether depression would mediate the association between physical fitness and academic achievement among this population. A total of 144 adolescents (M age = 14.55, SD = 0.62) were recruited from two middle schools. Health-related PF was significantly associated with depression, and skill-related PF was related to academic achievement. Mediation analysis supports the statistically significant indirect effect of depression on the relation between health-related PF and academic achievement. The findings suggest that individuals who are physically fit and show positive mental functioning may have better academic achievement during adolescence.
An Approximate Analytical Solution of the Fractional Diffusion Equation with Absorbent Term and External Force by Homotopy Perturbation Method

In the present paper, the approximate analytical solutions of a general diffusion equation with fractional time derivative in the presence of an absorbent term and a linear external force are obtained with the help of the powerful homotopy perturbation method (HPM). By using initial values, the approximate analytical solutions of the equation are derived. The results are deduced for different particular cases. The numerical results show that only a few iterations are needed to obtain accurate approximate solutions and these are presented graphically. The presented method is extremely simple, concise, and highly efficient as a mathematical tool in comparison with the other existing techniques.
Zero Energy Sag Correctors - Optimizing Dynamic Voltage Restorers for Industrial Applications

Plants and processes with a high level of industrial automation are most severely affected by short duration power disturbances. Such plants are most frequently fed from highly reliable utility grids, with measured reliability levels that are consistently in excess of 3 - 5 nines, yet face hours of unscheduled downtime resulting from short duration voltage sags. Extensive data confirms that such plants experience, on an average 30 power disturbances annually, of which over 95% are short duration disturbances lasting on an average no more than 6 cycles. Data also confirms that over 90% of these disturbances are asymmetrical faults. This paper shows a new approach to protecting industrial plants from power disturbances by building on the fact that it is prohibitively expensive to protect against all possible power disturbances, and that cost-effective protection is based on a statistical assessment of disturbances recorded and equipment susceptibility. This paper shows that it is possible to use a new family of zero energy sag correctors to realize protection against over 96-98% of all power disturbances. The paper also develops the design guidelines for such sag correctors, and shows simulation and experimental results for the new DVR system.
Assessing situated knowledge in secondary teacher training by using video cases

Experienced teachers subconsciously make use of situated knowledge, which is knowledge that is readily available, holistic, contextual and linked to specific situations, in order to solve incidents in everyday teaching. Situated knowledge is important in teaching and should therefore be assessed in teacher training programmes. Situated knowledge can be assessed by using cases and by setting higher learning objectives, on condition that both explicitlty address the situated nature of this knowledge. The main question in this study is: Do teacher trainers use cases that are aimed at acquiring situated knowledge? Emprirical research carried out in eleven secondary teacher-training programmes revealed that only one of these programmes indeed assessed situated knowledge.
Tumor Dormancy Induced by Downregulation of Urokinase Receptor in Human Carcinoma Involves Integrin and MAPK Signaling

Mechanisms that regulate the transition of metastases from clinically undetectable and dormant to progressively growing are the least understood aspects of cancer biology. Here, we show that a large (∼70%) reduction in the urokinase plasminogen activator receptor (uPAR) level in human carcinoma HEp3 cells, while not affecting their in vitro growth, induced a protracted state of tumor dormancy in vivo, with G0/G1 arrest. We have now identified the mechanism responsible for the induction of dormancy. We found that uPA/uPAR proteins were physically associated with α5β1, and that in cells with low uPAR the frequency of this association was significantly reduced, leading to a reduced avidity of α5β1 and a lower adhesion of cells to the fibronectin (FN). Adhesion to FN resulted in a robust and persistent ERK1/2 activation and serum-independent growth stimulation of only uPAR-rich cells. Compared with uPAR-rich tumorigenic cells, the basal level of active extracellular regulated kinase (ERK) was four to sixfold reduced in uPAR-poor dormant cells and its stimulation by single chain uPA (scuPA) was weak and showed slow kinetics. The high basal level of active ERK in uPAR-rich cells could be strongly and rapidly stimulated by scuPA. Disruption of uPAR–α5β1 complexes in uPAR-rich cells with antibodies or a peptide that disrupts uPAR–β1 interactions, reduced the FN-dependent ERK1/2 activation. These results indicate that dormancy of low uPAR cells may be the consequence of insufficient uPA/uPAR/α5β1 complexes, which cannot induce ERK1/2 activity above a threshold needed to sustain tumor growth in vivo. In support of this conclusion we found that treatment of uPAR-rich cells, which maintain high ERK activity in vivo, with reagents interfering with the uPAR/β1 signal to ERK activation, mimic the in vivo dormancy induced by downregulation of uPAR.
CT colonography with teleradiology: effect of lossy wavelet compression on polyp detection--initial observations.

PURPOSE To assess the consequences of lossy compression on the diagnostic accuracy of CT colonography for detecting colonic polyps. MATERIALS AND METHODS Helical CT images of cleansed colonic segments were evaluated. Source images were compressed to 1:1, 10:1, and 20:1 ratios with lossy wavelet compression. Two independent readers blinded to corresponding colonoscopic results analyzed 144 randomly ordered colonic segments in multiplanar and volume-rendered endoscopic views. Sensitivity, specificity, and receiver operating characteristic curves were generated for each compression ratio on the basis of expressed confidence in lesion presence. Similar analyses were performed to assess distention and bowel preparation adequacy and evaluation time required. RESULTS Results based on video colonoscopy-confirmed lesions revealed 100% (four of four) sensitivity for lesions larger than 10 mm for compression ratios 1:1, 10:1, and 20:1 for both readers; sensitivities for all lesions smaller than 10 mm were 50%-78%, 38%-67%, and 38%-67% for respective ratios for both readers. Differences in diagnostic performance for each reader across ratios were not significant (P =.30-.99, McNemar test). The time required to evaluate and assess bowel preparation and distention adequacy did not change significantly across ratios. CONCLUSION On the basis of the patient sample, lossy compression of transverse source images to at least a 20:1 ratio did not adversely affect diagnostic performance or evaluation time for CT colonography.
Motivations and measurements in an agile case study

With the recent emergence of agile software development technologies, the software community is awaiting sound, empirical investigation of the impacts of agile practices in a live setting. One means of conducting such research is through industrial case studies. However, there are a number of influencing factors that contribute to the success of such a case study. In this paper, we describe a case study performed at Sabre Airline Solutions evaluating the effects of adopting Extreme Programming (XP) practices with a team that had characteristically plan-driven risk factors. We compare the team's business-related results (productivity and quality) to two published sources of industry averages. Our case study found that the Sabre team yielded above-average post-release quality and average to above-average productivity. We discuss our experience in conducting this case study, including specifics of how data was collected, the rationale behind our process of data collection, and what obstacles were encountered during the case study. We also identify four factors that potentially impact the outcome of industrial case studies: availability of data, tool support, co-operative personnel and project status. We believe that recognizing and planning for these factors is essential to conducting industrial case studies, and that this information will be helpful to researchers and practitioners alike.
Is There an Association Between Carotid-Femoral Pulse Wave Velocity and Coronary Heart Disease in Patients with Coronary Artery Disease: A Pilot Study

Arterial stiffness has been shown to predict cardiovascular morbidity and mortality. Carotid-femoral pulse wave velocity (cfPWV) is regarded the gold standard marker of arterial stiffness. In previous studies, cfPWV was associated with the presence of coronary heart disease (CHD). However, with regard to CHD severity as assessed by the Syntax Score, only brachial-ankle PWV was reported to correlate with Syntax Score; no data exist for cfPWV. In this pilot study, we evaluated the possible associations between cfPWV, CHD and Syntax Score in 62 consecutive pa-tients (49 males; mean age: 64±12years) with chest pain undergoing scheduled coronary angiography. cfPWV was signifi-cantly higher in CHD patients than in non-CHD individuals (10 vs. 8.4 m/s; p = 0.003). No significant association was found between cfPWV and CHD severity as assessed by Syntax Score. A cut-off point of 12.3 m/s was considered as diagnostic for abnormally increased cfPWV (specificity: 97%; sensitivity: 12%; positive likelihood ratio: 3.558). Further research is needed to establish the relationship between cfPWV and Syntax Score.
Young men and women’s implicit attitudes towards consensually nonmonogamous relationships

ABSTRACT Recent research has revealed some inconsistencies in the traditionally negative attitudes towards consensual nonmonogamy (CNM; sexually and/or emotionally nonexclusive romantic relationships), with some adults reporting fairly neutral attitudes. These inconsistencies may be related to the effects of socially desirable responding when adopting self-report (e.g. explicit) measures. Thus, the current study assessed young men and women’s implicit attitudes towards CNM (using the Implicit Association Test) in order to bypass issues associated with social desirability bias. The results from 204 college students (81 men, 123 women) revealed that, despite reporting neutral explicit attitudes towards CNM, young men and women demonstrated a strong automatic preference for monogamy (mean D score = 0.71; SD = 0.32). Furthermore, the relationship between explicit and implicit attitudes was clarified by assessing the extent to which participants were likely to engage in socially desirable responding. Implicit and explicit attitudes towards CNM were more closely related among those less likely to evidence social desirability bias as compared to those who were more likely to fall prey to this bias. These findings highlight the importance of assessing implicit attitudes and provide evidence of the strong social stigma surrounding CNM.
Comparative Analysis of Bacterial Communities in a Potato Field as Determined by Pyrosequencing

Background Plants selectively attract particular soil microorganisms, in particular consumers of root-excreted compounds. It is unclear to what extent cultivar type and/or growth stage affect this process. Methodology/Principal Findings DNA-based pyrosequencing was used to characterize the structure of bacterial communities in a field cropped with potato. The rhizospheres of six cultivars denoted Aveka, Aventra, Karnico, Modena, Premiere and Desiree, at three growth stages (young, flowering and senescence) were examined, in addition to corresponding bulk soils. Around 350,000 sequences were obtained (5,700 to 38,000 per sample). Across all samples, rank abundance distributions best fitted the power law model, which indicates a community composed of a few highly dominant species next to numerous rare species. Grouping of the sequences showed that members of the Actinobacteria, Alphaproteobacteria, next to as-yet-unclassified bacteria, dominated. Other groups that were consistently found, albeit at lower abundance, were Beta-, Gamma- and Deltaproteobacteria and Acidobacteria. Principal components analyses revealed that rhizosphere samples were significantly different from corresponding bulk soil in each growth stage. Furthermore, cultivar effects were found in the young plant stage, whereas these became insignificant in the flowering and senescence stages. Besides, an effect of time of season was observed for both rhizosphere and bulk soils. The analyzed rhizosphere samples of the potato cultivars were grouped into two groups, in accordance with the allocation of carbon to starch in their tubers, i.e. Aveka, Aventra and Karnico (high) versus Premiere and Desiree (low) and thus replicates per group were established. Conclusions Across all potato cultivars, the young plant stages revealed cultivar-dependent bacterial community structures, which disappeared in the flowering and senescence stages. Furthermore, Pseudomonas, Beta-, Alpha- and Deltaproteobacteria flourished under different ecological conditions than the Acidobacteria.
Roles of NIA/NR/NOA1-dependent nitric oxide production and HY1 expression in the modulation of Arabidopsis salt tolerance

Despite substantial evidence on the separate roles of Arabidopsis nitric oxide-associated 1 (NOA1)-associated nitric oxide (NO) production and haem oxygenase 1 (HY1) expression in salt tolerance, their integrative signalling pathway remains largely unknown. To fill this knowledge gap, the interaction network among nitrate reductase (NIA/NR)- and NOA1-dependent NO production and HY1 expression was studied at the genetic and molecular levels. Upon salinity stress, the majority of NO production was attributed to NIA/NR/NOA1. Further evidence confirmed that HY1 mutant hy1-100, nia1/2/noa1, and nia1/2/noa1/hy1-100 mutants exhibited progressive salt hypersensitivity, all of which were significantly rescued by three NO-releasing compounds. The salinity-tolerant phenotype and the stronger NO production in gain-of-function mutant of HY1 were also blocked by the NO synthetic inhibitor and scavenger. Although NO- or HY1-deficient mutants showed a compensatory mode of upregulation of HY1 or slightly increased NO production, respectively, during 2 d of salt treatment, downregulation of ZAT10/12-mediated antioxidant gene expression (cAPX1/2 and FSD1) was observed after 7 d of treatment. The hypersensitive phenotypes and stress-related genes expression profiles were differentially rescued or blocked by the application of NO- (in particular) or carbon monoxide (CO)-releasing compounds, showing a synergistic mode. Similar reciprocal responses were observed in the nia1/2/noa1/hy1-100 quadruple mutant, with the NO-releasing compounds exhibit the maximal rescuing responses. Overall, the findings present the combination of compensatory and synergistic modes, linking NIA/NR/NOA1-dependent NO production and HY1 expression in the modulation of plant salt tolerance.
Magnetic Resonance Spectroscopic Findings of Chronic Lesions in Two Subtypes of Multiple Sclerosis: Primary Progressive Versus Relapsing Remitting

Background Multiple sclerosis (MS) is a highly prevalent cause of neurological disability and has different clinical subtypes with potentially different underlying pathologies. Differentiation of primary progressive multiple sclerosis (PPMS) from relapsing remitting multiple sclerosis (RRMS) could be difficult especially in its early phases. Objectives We compared brain metabolite concentrations and ratios in patients with PPMS and RRMS by magnetic resonance spectroscopic imaging (MRSI). Patients and Methods Thirty patients with definite MS (15 with RRMS and 15 with PPMS) underwent MRSI and their non-enhancing lesion metabolites were measured. N-acetyl aspartate (NAA), Creatine (Cr), Choline (Cho), NAA/Cr and NAA/Cho were measured and compared between the two MS subtypes. Results When the two MS groups were compared together, we found that Cr was significantly increased (P value=0.008) and NAA/Cr was significantly decreased (P value=0.03) in non-enhancing lesions in PPMS compared with RRMS. There was no significant difference in NAA, Cho or NAA/Cho between the two MS subtypes. Conclusion MRS is a potential way to differentiate PPMS and RRMS.
The Hitchhiker's Guide to Cross-Platform OpenCL Application Development

One of the benefits to programming of OpenCL is platform portability. That is, an OpenCL program that follows the OpenCL specification should, in principle, execute reliably on any platform that supports OpenCL. To assess the current state of OpenCL portability, we provide an experience report examining two sets of open source benchmarks that we attempted to execute across a variety of GPU platforms, via OpenCL. We report on the portability issues we encountered, where applications would execute successfully on one platform but fail on another. We classify issues into three groups: (1) framework bugs, where the vendor-provided OpenCL framework fails; (2) specification limitations, where the OpenCL specification is unclear and where different GPU platforms exhibit different behaviours; and (3) programming bugs, where non-portability arises due to the program exercising behaviours that are incorrect or undefined according to the OpenCL specification. The issues we encountered slowed the development process associated with our sets of applications, but we view the issues as providing exciting motivation for future testing and verification efforts to improve the state of OpenCL portability; we conclude with a discussion of these.