Miracle-dz/UniFAR-FTUs huggingface dataset:
Picture This: the Impact of Mobile Camera Phones on Personal Photographic Practices

: In a post-modern age, memories are no longer Proustian madeleines, but photographs. The past has become a collection of photographic, ﬁlmic or televisual images. We, like the replicants [of Blade Runner ], are put in the position of reclaiming a history by means of its reproduction. (Bruno, 1990, p. 183)
Social Desirability, Environmental Attitudes, and General Ecological Behaviour in Children

Socially desirable responses have been widely discussed as potentially biasing self-reported measures of environmental attitude and behaviour assessment. The direct and moderating effect of social desirability on children has not been analysed before. By applying a Lie scale together with a two-factor environmental attitude set measure and a scale of self-reported General Ecological Behaviour (GEB) to 198 pupils, we found a moderate impact of Lie scores on only one of both attitude measures and a small impact on GEB. In a multiple regression analysis general behaviour was predicted by attitude, social desirability, and the interaction of both. Social desirability had no moderating effect on the relationship between environmental attitudes and behaviour. Implications of these outcomes for research on environmental issues with children are discussed.
A STUDY OF THE SERUM PROTEIN CHANGES IN PREGNANCY AND TOXAEMIA, USING PAPER STRIP ELECTROPHORESIS

METHOD Paper Strip Electrophoresis The inverted V apparatus as suggested by Flynn and de Mayo (1951) and Whatman No. 1 filter paper were employed. The electrophoretic buffer consisted of 1 a03 grams per cent of sodium diethylbarbiturate and 0.184 grams per cent of diethyl barbituric acid. Each electrophoretic strip was run in the apparatus for 18 hours at 150 volts, and then dried rapidly in a current of warm air. The strips were stained with azocarmine B (Gurr) by the method of Pliickthun and Gotting (1951). Each batch of dye was checked for stability when made up into solution and for constancy of composition by using paper chromatography with a butylacetic-water solvent (5.1.4) (Franglen and Martin, 1954). Each stained strip was then interpreted by a reflecting photo-densitometer (Latner, Molyneux and Rose, 1954). This instrument, with a triangular wedge, does not give a linear relationship between the amount of dye present and the amount of protein present. This error was corrected by using the type of instrument since suggested by Latner in 1955. In order to convert each protein fraction into grams of protein the correction factors as suggested by Loeffler and Wunderly (1953) were used. The total protein was determined by the MicroKjeldahl method.
Beyond TQM Programmes

The failure rate of TQM interventions exceeds 75 per cent. Contends that it is missteps in the implementation of TQM – and other associated change efforts such as process re‐engineering – that undermine the likelihood that the intervention will contribute in a significant and lasting way to the competitive effectiveness of the organization. Using three case examples of TQM efforts, suggests that the implementation process must succeed in unhooking the organization from its traditional hierarchical and functional moorings and reattach it to horizontal, cross‐functional processes. To do this, the intervention process must address six distinct but interconnected stages of unhooking and reattachment and do so in a logical, sequential way.
Role of dopamine D2 receptors in optimizing choice strategy in a dynamic and uncertain environment

In order to investigate roles of dopamine receptor subtypes in reward-based learning, we examined choice behavior of dopamine D1 and D2 receptor-knockout (D1R-KO and D2R-KO, respectively) mice in an instrumental learning task with progressively increasing reversal frequency and a dynamic two-armed bandit task. Performance of D2R-KO mice was progressively impaired in the former as the frequency of reversal increased and profoundly impaired in the latter even with prolonged training, whereas D1R-KO mice showed relatively minor performance deficits. Choice behavior in the dynamic two-armed bandit task was well explained by a hybrid model including win-stay-lose-switch and reinforcement learning terms. A model-based analysis revealed increased win-stay, but impaired value updating and decreased value-dependent action selection in D2R-KO mice, which were detrimental to maximizing rewards in the dynamic two-armed bandit task. These results suggest an important role of dopamine D2 receptors in learning from past choice outcomes for rapid adjustment of choice behavior in a dynamic and uncertain environment.
Differentially expressed microRNAs at different stages of atherosclerosis in ApoE-deficient mice.

BACKGROUND Atherosclerosis is the primary cause of cardiovascular disease, carotid artery disease, and peripheral vascular disease. However, it is hard to obtain human arterial tissue at different stages of atherosclerosis for a systematic study. The ApoE-deficient (ApoE(-/-)) mice predictably develop spontaneous atherosclerotic plaques with numerous features similar to the human lesions and contain nearly the entire spectrum of lesions observed during atherogenesis in humans. MicroRNA expression profiles at different stages of atherosclerosis in ApoE-deficient mice were screened to find out the differentially expressed microRNAs. METHODS ApoE-deficient mice were euthanized at 4, 8, and 20 weeks of age and divided into three groups according to the three time points, including groups A4 (fed a Western-type diet for 0 week), A8 (fed a Western-type diet for 4 weeks), and A20 (fed a Western-type diet for 16 weeks). Atherosclerotic lesions were analyzed. Fifteen aortas were collected and combined into three pools (five aortas in one pool) in each group. MicroRNA microarray analysis was replicated thrice in each group. The threshold of fold change ≥ 2.0 was used to screen up or down-regulated microRNAs. Differentially expressed microRNAs were subsequently verified with quantitative real-time polymerase chain reaction. Those increasingly up or down-regulated microRNAs during the progression of atherosclerosis were selected. RESULTS Atherosclerotic lesions first appeared in the aortic arch in group A8. Severe atherosclerotic lesions were observed in group A20. In group A8, seven MicroRNAs were up-regulated while two were down-regulated. In group A20, 15 microRNAs were up-regulated while two were down-regulated. miR-34a-5p and miR-497-5p were increasingly up-regulated, while miR-434-3p was progressively down-regulated when atherosclerosis progressed. CONCLUSIONS In this study, we described that microRNAs are differentially expressed at different stages of atherosclerosis in ApoE-deficient mice. Those increasingly up or down-regulated microRNAs during the progression of atherosclerosis may play an important role in the pathogenesis of atherosclerosis and provide us opportunities for investigating atherosclerosis from early to advanced stages.
Comparative landscape genetic analyses show a Belgian motorway to be a gene flow barrier for red deer (Cervus elaphus), but not wild boars (Sus scrofa)

While motorways are often assumed to influence the movement behaviour of large mammals, there are surprisingly few studies that show an influence of these linear structures on the genetic make‐up of wild ungulate populations. Here, we analyse the spatial genetic structure of red deer (Cervus elaphus) and wild boars (Sus scrofa) along a stretch of motorway in the Walloon part of Belgium. Altogether, 876 red deer were genotyped at 13 microsatellite loci, and 325 wild boars at 14 loci. In the case of the red deer, different genetic clustering tools identified two genetic subpopulations whose borders matched the motorway well. Conversely, no genetic structure was identified in the case of the wild boar. Analysis of isolation‐by‐distance patterns of pairs of individuals on the same side and on different sides of the motorway also suggested that the road was a barrier to red deer, but not to wild boar movement. While telemetry studies seem to confirm that red deer are more affected by motorways than wild boar, the red deer sample size was also much larger than that of the wild boars. We therefore repeated the analysis of genetic structure in the red deer with randomly sub‐sampled data sets of decreasing size. The power to detect the genetic structure using clustering methods decreased with decreasing sample size.
The Role of Seagrass Traits in Mediating Zostera noltei Vulnerability to Mesograzers

Understanding how intra-specific differences in plant traits mediate vulnerability to herbivores of relevant habitat-forming plants is vital to attain a better knowledge on the drivers of the structure and functioning of ecosystems. Such studies, however, are rare in seagrass-mesograzer systems despite the increasingly recognized relevance of mesograzers as seagrass consumers. We investigated the role and potential trade-offs of multiple leaf traits in mediating the vulnerability of the seagrass Zostera noltei to different mesograzer species, the amphipod Gammarus insensibilis and the isopod Idotea chelipes. We worked with plants from two different meadows for which contrasting chemical and structural traits were expected based on previous information. We found that plants with high vulnerability to mesograzers (i.e. those preferred and subjected to higher rates of leaf area loss) had not only higher nitrogen content and lower C:N, fibre, and phenolics, but also tender and thinner leaves. No trade-offs between chemical and structural traits of the seagrass were detected, as they were positively correlated. When leaf physical structure was removed using agar-reconstituted food, amphipod preference towards high-susceptibility plants disappeared; thus indicating that structural rather than chemical traits mediated the feeding preference. Removal of plant structure reduced the size of isopod preference to less than half, indicating a stronger contribution of structural traits (> 50%) but combined with chemical/nutritional traits in mediating the preference. We then hypothesized that the high environmental nutrient levels recorded in the meadow exhibiting high susceptibility modulate the differences observed between meadows in seagrass traits. To test this hypothesis, we exposed low-vulnerability shoots to eutrophic nutrient levels in a 6-week enrichment experiment. Nutrient enrichment increased Z. noltei nitrogen content and lowered C:N, fibre, and phenolics, but had no effect on structural traits. Overall, our findings help to better understand the trait-mediated seagrass susceptibility to mesograzers and reinforce the increasingly recognized role of structural defences against herbivory.
Oxidative stress in testicular tissues of rats exposed to cigarette smoke and protective effects of caffeic acid phenethyl ester.

AIM To show the oxidative stress after cigarette smoke exposure in rat testis and to evaluate the effects of caffeic acid phenethyl ester (CAPE). METHODS Twenty-one rats were divided into three groups of seven. Animals in Group I were used as control. Rats in Group II were exposed to cigarette smoke only (4 x 30 min/d) and rats in Group III were exposed to cigarette smoke and received daily intraperitoneal injections of CAPE (10 micromol/kg x d). After 60 days all the rats were killed and the levels of nitric oxide (NO) and anti-oxidant enzymes such as superoxide-dismutase, catalase and glutathione peroxidase (GSH-Px) and the level of malondialdehyde were studied in the testicular tissues of rats with spectrophotometric analysis. RESULTS There was a significant increase in catalase and superoxide-dismutase activities in Group II when compared to the controls, but the levels of both decreased after CAPE administration in Group III. GSH-Px activity was decreased in Group II but CAPE caused an elevation in GSH-Px activity in Group III. The difference between the levels of GSH-Px in Group I and Group II was significant, but the difference between groups II and III was not significant. Elevation of malondialdehyde after smoke exposure was significant and CAPE caused a decrease to a level which was not statistically different to the control group. A significantly increased level of NO after exposure to smoke was reversed by CAPE administration and the difference between NO levels in groups I and III was statistically insignificant. CONCLUSION Exposure to cigarette smoke causes changes in the oxidative enzyme levels in rat testis, but CAPE can reverse these harmful effects.
Peruvians’ sleep duration: analysis of a population-based survey on adolescents and adults

Background. Sleep duration, either short or long, has been associated with diseases such as obesity, type-2 diabetes and cardiovascular diseases. Characterizing the prevalence and patterns of sleep duration at the population-level, especially in resource-constrained settings, will provide informative evidence on a potentially modifiable risk factor. The aim of this study was to explore the patterns of sleep duration in the Peruvian adult and adolescent population, together with its socio-demographic profile. Material and Methods. A total of 12,424 subjects, mean age 35.8 years (SD ±17.7), 50.6% males, were included in the analysis. This is a cross-sectional study, secondary analysis of the Use of Time National Survey conducted in 2010. We used weighted means and proportions to describe sleep duration according to socio-demographic variables (area and region; sex; age; education attainment; asset index; martial and job status). We used Poisson regressions, taking into account the multistage sampling design of the survey, to calculate crude and adjusted prevalence ratios (PR) and 95% confidence intervals (95% CI). Main outcomes were short- (<6 h) and long-sleep duration (≥ 9 h). Results. On average, Peruvians slept 7.7 h (95% CI [7.4–8.0]) on weekdays and 8.0 h (95% CI [7.8–8.1]) during weekends. The proportions of short- and long-sleep, during weekdays, were 4.3% (95% CI [2.9%–6.3%]) and 22.4% (95% CI [14.9%–32.1%]), respectively. Regarding urban and rural areas, a much higher proportion of short-sleep was observed in the former (92.0% vs. 8.0%); both for weekdays and weekends. On the multivariable analysis, compared to regular-sleepers (≥ 6 to <9 h), short-sleepers were twice more likely to be older and to have higher educational status, and 50% more likely to be currently employed. Similarly, relative to regular-sleep, long-sleepers were more likely to have a lower socioeconomic status as per educational attainment. Conclusions. In this nationally representative sample, the sociodemographic profile of short-sleep contrasts the long-sleep. These scenarios in Peru, as depicted by sleeping duration, differ from patterns reported in other high-income settings and could serve as the basis to inform and to improve sleep habits in the population. Moreover, it seems important to address the higher frequency of short-sleep duration found in urban versus rural settings.
Mapping Reflexive Body Techniques: On Body Modification and Maintenance

This article aims to do two things. The first of these is to introduce the concept of reflexive body techniques into the debate on body modification/maintenance. The value of the concept in relation to this debate, in part, is that it ensures that we conceive of the body as both a subject and an object, modifier and modified, and that we thereby avoid the trap of conceptualizing modification in dualistic (mind/body or body/society) terms. Second, the article seeks to explore the pattern of distribution of practices of modification (conceived as reflexive body techniques) through society and to reflect upon the potential usefulness of multi-dimensional scaling as a tool for doing this. This aim is related to the first aim as it is argued that the concept of reflexive body techniques serves to identify and anchor practices ofmodification in a way that is amenable to both quantitative and qualitative forms of analysis, as well as theoretical investigation.
What works for doctoral students in completing their thesis?

Writing a thesis is one of the most challenging activities that a doctoral student must undertake and can represent a barrier to timely completion. This is relevant in light of current and widespread concerns regarding doctoral completion rates. This study explored thesis writing approaches of students post or near Ph.D. completion through interviews. The study's aim was to highlight factors identified by participants as helpful or hindering thesis writing. The analysis revealed ‘helpful’ factors were related to students' intrinsic behaviours and supervisory support, particularly support that adopted a ‘project-management’ style. Additionally, a subgroup of participants discussed the merits of a continuous-writing approach which is further explored in this paper with reference to the notion of writing to develop knowledge; this is recommended for timely Ph.D. completion.
Haematological and Immunological Responses in Juvenile Sea Bass (Dicentrarchus labrax L.) After Short-Term Acute Stress

The physiological effects of acute stress (induced by an intraperitoneal injection) on the haematocrit, haemo- globin, serum cortisol and glucose, haemagglutinins and lysozyme were investigated in juvenile sea bass Dicentrarchus labrax. A total of 40 fish were subjected to an intraperitoneal injection. Eight fish were sampled at 0, 2, 4, 24 and 48 h af- ter acute stress and compared to unstressed fish (controls) sacrificed at the same times. Intraperitoneal injection resulted in significant changes in cortisol and glucose 4 and 2 hours after exposure to stress, respectively, but not in haematocrit and haemoglobin levels. No significant differences between stressed and control fish were recorded for lysozyme content and haemagglutinating activity throughout the experiment. In juvenile sea bass acute stress caused by intraperitoneal injection was mostly associated with the increase in common stress indicators (cortisol and glucose), while no clear response in terms of non-specific immune parameters was evidenced.
Turnover of the plasma binding protein for vitamin D and its metabolites in normal human subjects.

The turnover of the plasma binding protein for vitamin D and its metabolites (DBP) was investigated in four normal young men. 125I-Labeled DBP was injected iv into each subject, and the plasma specific radioactivity-time curve was determined for the following 15–18 days. All urine was collected during the study, and the cumulative urinary 125I excretion curve was determined. The serum and urinary radioactivity data were analyzed by compartmental analysis using a weighted, least squares, nonlinear regression technique. In each of the subjects studied, a three-pool model provided the best fit to the serum specific radioactivity-time data. A three-pool, catenary model was selected on the basis of physiological considerations. The urinary data were fit by assuming a single outflow from pool 1 into an iodide compartment. Total body exchangeable DBP averaged 2.89 g. The production rate of DBP varied from 0.69–0.93 g/day in the subjects studied, with a mean of 10.1 mg/kg BW · day. Inferences could be drawn about.
Production and perception of communicatory signals in a noisy environment

Many animals communicate in situations that make it difficult to discriminate a species' signals from those of others. Consequently, coexisting species usually have signals that differ by more than the minimum required to prevent overlap in acoustic features. These gaps between signals might facilitate detection and discrimination of degraded signals in noisy natural conditions. If so, perception of signals should have broader scope than production. We investigated this possibility by studying song production and perception of two species of birds in an especially noisy environment, the Amazonian dawn chorus. With software developed for this study, we digitally synthesized songs of two species, as well as intermediate versions of their songs. Experimental playbacks of these synthesized songs to individuals of both species confirmed that perception (as indicated by responses) was broader than production of songs. We propose that broader perception than production of song promotes communication in noisy situations and limits the similarity between signals of coexisting species.
Testosterone is associated with harem maintenance ability in free-ranging grey-headed flying-foxes, Pteropus poliocephalus

Males of many vertebrate species aggressively defend their reproductive interests by monopolizing females, and the ‘challenge hypothesis’ predicts that testosterone levels in reproductive contexts rise to facilitate males' competitive behaviours necessary for meeting social challenges. The hypothesis is successful in explaining patterns of testosterone secretion in many avian species, but remains comparatively unexplored in mammals. ‘Circulating plasma testosterone levels (T)’ were studied in relation to harem maintenance in grey-headed flying-foxes, Pteropus poliocephalus. In this species, harems provide mating opportunities and so a male's ability to maintain a harem is likely to correlate with his fitness. We hypothesized that if T reflect a male's ability to withstand challenges from competitors, then T should be linked to successful harem maintenance. To test this, we temporarily removed males from their territories prior to and during the short mating period, recording their harem sizes both before removal and after reintroduction. Most males successfully reclaimed their territory and a harem, but during the mating period, males with higher T had harems closer to their original size, and males with lower T suffered reduction in harem size. Our findings highlight the role of T in harem maintenance in a major mammalian taxon with complex forms of social organization.
Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain.

CONTEXT Although chest pain is widely considered a key symptom in the diagnosis of myocardial infarction (MI), not all patients with MI present with chest pain. The extent to which this phenomenon occurs is largely unknown. OBJECTIVES To determine the frequency with which patients with MI present without chest pain and to examine their subsequent management and outcome. DESIGN Prospective observational study. SETTING AND PATIENTS A total of 434,877 patients with confirmed MI enrolled June 1994 to March 1998 in the National Registry of Myocardial Infarction 2, which includes 1674 hospitals in the United States. MAIN OUTCOME MEASURES Prevalence of presentation without chest pain; clinical characteristics, treatment, and mortality among MI patients without chest pain vs those with chest pain. RESULTS Of all patients diagnosed as having MI, 142,445 (33%) did not have chest pain on presentation to the hospital. This group of MI patients was, on average, 7 years older than those with chest pain (74.2 vs 66.9 years), with a higher proportion of women (49.0% vs 38.0%) and patients with diabetes mellitus (32.6% vs 25. 4%) or prior heart failure (26.4% vs 12.3%). Also, MI patients without chest pain had a longer delay before hospital presentation (mean, 7.9 vs 5.3 hours), were less likely to be diagnosed as having confirmed MI at the time of admission (22.2% vs 50.3%), and were less likely to receive thrombolysis or primary angioplasty (25.3% vs 74.0%), aspirin (60.4% vs 84.5%), beta-blockers (28.0% vs 48.0%), or heparin (53.4% vs 83.2%). Myocardial infarction patients without chest pain had a 23.3% in-hospital mortality rate compared with 9.3% among patients with chest pain (adjusted odds ratio for mortality, 2. 21 [95% confidence interval, 2.17-2.26]). CONCLUSIONS Our results suggest that patients without chest pain on presentation represent a large segment of the MI population and are at increased risk for delays in seeking medical attention, less aggressive treatments, and in-hospital mortality. JAMA. 2000;283:3223-3229