Miracle-dz/UniFAR-FTUs huggingface dataset:
Fine‐needle aspiration cytology of metastatic nasopharyngeal carcinoma

Over a 32‐month period at the University Hospital, Kuala Lumpur, we were able to study the cytological appearance of metastatic nasopharyngeal carcinoma (NPC) in 17 cases. This comprised 14 males and three females of which 13 were Chinese, three were Malay, and one was Indian. Their ages ranged from 27 to 64 years. Histological correlation was available in all the patients in the form of nasopharyngeal biopsies, and they were classified as per the World Health Organization classification into types I, II, and III NPC. Smears from type II NPC showed good cellularity with mainly clustered and occasionally dissociated cells, with focal columnar appearance, vesicular nuclei, prominent nucleoli, and variable amounts of cytoplasm. Clusters of malignant cells closely associated with lymphoid cells and dissociation of malignant cells were more characteristic of type III NPC.
I/Q Imbalance in AF Dual-Hop Relaying: Performance Analysis in Nakagami-m Fading

We analyze the performance of amplify-and-forward dual-hop relaying systems in the presence of in-phase and quadrature-phase imbalance (IQI) at the relay node. In particular, an exact analytical expression for and tight lower bounds on the outage probability are derived over independent, non-identically distributed Nakagami-m fading channels. Moreover, tractable upper and lower bounds on the ergodic capacity are presented at arbitrary signal-to-noise ratios (SNRs). Some special cases of practical interest (e.g., Rayleigh and Nakagami-0.5 fading) are also studied. An asymptotic analysis is performed in the high SNR regime, where we observe that IQI results in a ceiling effect on the signal-to-interference-plus-noise ratio (SINR), which depends only on the level of I/Q impairments, i.e., the joint image rejection ratio. Finally, the optimal I/Q amplitude and phase mismatch parameters are provided for maximizing the SINR ceiling, thus improving the system performance. An interesting observation is that, under a fixed total phase mismatch constraint, it is optimal to have the same level of transmitter (TX) and receiver (RX) phase mismatch at the relay node, while the optimal values for the TX and RX amplitude mismatch should be inversely proportional to each other.
Development Of 5.8 GHz Microstrip Parallel Coupled Line Bandpass Filter For Wireless Communication System

This paper aim to present the design technique, parameter analysis, real prototype fabrication and measurement results compare to simulation of 5.8GHz rectangular microstrip inset feed patch antenna. The antenna design calculation, simulation study and practical measurement results are well presented and compared. This study would be useful to realize low cost 5.8GHz rectangular microstrip patch antenna for any appropriate system developments and investigate the parameter study. The information shared is aimed to serve the similar scientific field and improve the system features.
PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization

The lipid phosphatidylinositol-4,5-bisphosphate (PtdIns[4,5]P2) appears to play an important role in endocytosis. However, the timing of its formation and turnover, and its specific functions at different stages during endocytic internalization, have not been established. In this study, Sla2 ANTH-GFP and Sjl2-3GFP were expressed as functional fusion proteins at endogenous levels to quantitatively explore PtdIns(4,5)P2 dynamics during endocytosis in yeast. Our results indicate that PtdIns(4,5)P2 levels increase and decline in conjunction with coat and actin assembly and disassembly, respectively. Live-cell image analysis of endocytic protein dynamics in an sjl1Δ sjl2Δ mutant, which has elevated PtdIns(4,5)P2 levels, revealed that the endocytic machinery is still able to assemble and disassemble dynamically, albeit nonproductively. The defects in the dynamic behavior of the various endocytic proteins in this double mutant suggest that PtdIns(4,5)P2 turnover is required for multiple stages during endocytic vesicle formation. Furthermore, our results indicate that PtdIns(4,5)P2 turnover may act in coordination with the Ark1/Prk1 protein kinases in stimulating disassembly of the endocytic machinery.
Fortune 500 Homepages: Design Trends

This study is a comprehensive census of the homepage design practices of Fortune 500 companies, analyzing 46 elements of homepage design. The analysis establishes recent design trends of Fortune 500 homepages. In addition, it provides a snapshot of recent homepage design practices of the Fortune 500 that can be used for comparison with other populations and for future research and longitudinal studies of web design.
Communities of practice and the construction of learners in post-compulsory education and training

Abstract This article draws upon data collected in three empirical studies focusing on different aspects of post-compulsory education: a study of staff development officers in further education (FE) in the Midlands, an exploration of trainee FE teachers understanding of further education in a new university and, finally, a study of teachers and learners involved in General National Vocational Qualifications (GNVQs) at one college. All studies were conducted in England. The article explores constructions of learners and relates these to the policy context within which postcompulsory education and training (PCET) is placed. It also considers the notion of communities of practice, as well as core and peripheral participation as a means to interrogate these constructions of learners.
How Do Internal Openness and External Openness Affect Innovation Capabilities and Firm Performance?

Open innovation is a paradigm that believes that firms should use both internal and external ideas. These ideas can advance technology and lead to competitive advantage, thereby improving a firm's performance. However, the process of turning innovative ideas into performance does depend on firms' innovation capabilities. In this study, we first divide “openness” into external openness, a search for external channels of information used to innovate, and internal openness, a kind of open culture within a firm. In order to balance value capture with openness, the power of openness in terms of value creation is largely supported by innovation capabilities, including the inherent characteristics of knowledge resources, absorptive capacity, and an entrepreneurial orientation. Our main goals are to state explicitly how a firm's openness strategies influence its innovation capabilities, and explore how to advance innovation capabilities through openness in order to improve performance. Therefore, we use an international and cross-industry survey which was executed by the Managing Innovation in the New Economy (MINE) program. Based on data from 393 firms, our results show that the innovation capabilities of these firms derive from the accumulation of external openness and internal openness. In addition, the findings of this study confirm the role of innovation capabilities in mediating the effect of openness strategies on firms' performance. On the whole, this investigation demonstrates the value of external openness and internal openness to promoting favorable managerial decisions.
Eye Contact and Grade Distribution

While teaching a large lecture course of art appreciation, I investigated whether grades vary by section to section in the auditorium. The auditorium was divided into nine sections containing 20 students per section. Students were seated by alphabetized lists, by Social Security numbers, or by selecting seats they wished to sit in for the duration of that semester. Two tests were given to each class, one on required reading and one on the slide/lectures. Regardless of the method of seating, students in the middle and the front sections achieved scores considerably higher than those in the rear sections. Although the class who chose where they wanted to sit was factored out (because brighter students might choose to sit in front or middle rows), those classes assigned to seats by alphabetized lists and Social Security numbers gave the same results. The only apparent difference between the sections in the auditorium was instructor/students' eye contact, so apparently the students gained a sense of personalization through eye contact with the instructor.
Male eastern phoebes (Sayornis phoebe; Tyrannidae, Passeriformes) fail to imitate songs.

To test for imitative ability of a suboscine, I exposed males of three groups of hand-reared eastern phoebes (Sayornis phoebe, Tyrannidae) to different tutor tapes during the first 70 days of life. Under these experimental conditions I found no evidence of an environmental influence on song development, which thus reinforces the idea that vocal development in the two passerine suborders is qualitatively different
Acceptability of Adaptations for Struggling Writers

One hundred twenty-five primary-grade teachers randomly selected from across the United States indicated how frequently they made 20 instructional adaptations for the struggling writers in their classroom. The measure of frequency ranged from never, several times a year, monthly, weekly, several times a week, and daily. Using a 6-point Likert-type scale, they also rated the acceptability of each of the 20 adaptations on five dimensions: suitability, effectiveness, negative effects, time to apply, and implementation know-how. Teachers reported making 13 different adaptations monthly or more often. The most common adaptations were extra encouragement and extra time to complete writing assignments, whereas the least common adaptations involved technology or dictation. Teachers viewed all of the adaptations as acceptable, and their views on acceptability made a unique and statistically significant contribution to predicting reported use of adaptations after variance due to student and other teacher variables was first controlled.
Do Funds Window Dress ? Evidence for U . S . Domestic Equity Mutual Funds ∗

It is not uncommon for mutual fund managers to make significant adjustments to their allocations before closing out their portfolios at the end of the quarter. The common wisdom on the street and in the financial press is that part of this activity is due to “window dressing” which has become widespread as investors are becoming increasingly sophisticated in analyzing fund holdings as well as past returns in an effort to detect manager skill. So far, the academic literature on equity mutual funds has provided little empirical evidence to this effect. We analyze the semi-annual holdings and daily net asset values of 4,025 U.S. domestic equity mutual funds over the period from 1997 to 2002 and find strong evidence of increased turnover during the last days of the quarter, consistent with window dressing. In particular, we show that growth funds and funds with poor recent performance are more likely to report misleading holding. Furthermore, the end of quarter trading activity is not easily accounted for by momentum/relative strength strategies and is not associated with strategies that on average provide any added value to investors, even before accounting for expenses. Nor can liquidity costs explain these findings. ∗We thank Annette Larson, Paul Kaplan, Robert Korajczyk, Robert McDonald, Todd Pulvino, Paula Tkac, participants at the Zell Center for Risk Research seminar at the Kellogg School of Management, the 2004 Hawaii International Conference on Business, the 2004 European Financial Management Association meetings, the JFE Conference on Delegated Portfolio Management in Eugene (Oregon), and seminar participants at HEC Montréal, and Tilburg University for their comments and suggestions. We would especially like to thank Ravi Jagannathan for numerous suggestions and many insightful discussions. We thank Morningstar, Inc. for providing us with the mutual fund data.
Attachment status and salivary cortisol in a normal day and during simulated interpersonal stress in young men

Attachment insecurity, as assessed via the adult attachment interview (AAI), may be expected to relate to basal hypothalamic–pituitary–adrenal (HPA) activity because it is retrodictive of stressful early experiences, which may influence HPA development. In addition, because AAI insecurity may reflect limitations on concurrent cognitive, emotional, and behavioral strategies for managing interpersonal distress, insecurity may also relate to cortisol reactivity specifically during inter-personal challenges. Nevertheless, only two studies have examined associations between AAI insecurity and cortisol, and in total only eight non-clinical men were included. To expand upon past research, the current study focused on college aged men and examined relations between attachment status (via categories and continuous scores) and cortisol levels during daily life and during interpersonal laboratory challenges, wherein subjects were asked to visualize and respond to hypothetical situations concerning loss, separation, and abandonment. Unlike prior research, salivary cortisol was measured during cognitive challenges (e.g. non-autobiographical memory tests), so as to inform questions concerning the specificity of effects. Contrary to expectations, only limited evidence suggested a relation between insecurity and basal HPA functioning. However, in keeping with expectations, associations between insecurity, and in particular dismissing idealization, and comparatively higher cortisol values following interpersonal challenges were observed.
How Do Reference Groups Influence Self-Brand Connections among Chinese Consumers?

This paper investigates the influence of reference groups on self-brand connections among Chinese consumers and the implications for advertising in China. Reference groups include the in-group (member group) and out-groups (aspiration, dissociative, and neutral). Two studies test five hypotheses involving both Chinese and foreign brands. The results indicate that Chinese consumers report higher self-brand connections for Chinese brands in member and aspiration group settings, but higher connections with foreign brands in a dissociative group setting. Furthermore, individualism/collectivism moderates the influence of reference groups on this connection. For brands with images congruent with the in-group, compared with more individualistic consumers, more collectivist consumers exhibit stronger self-brand connections with Chinese brands than with foreign brands. For brands with images congruent with the dissociative group, compared with more collectivist consumers, more individualistic consumers report stronger self-brand connections with foreign brands than with Chinese brands. These results have critical implications for advertising in China.
Cytosolic phospholipase A2&egr; drives recycling through the clathrin-independent endocytic route

ABSTRACT Previous studies have demonstrated that membrane tubule-mediated transport events in biosynthetic and endocytic routes require phospholipase A2 (PLA2) activity. Here, we show that cytosolic phospholipase A2&egr; (cPLA2&egr;, also known as PLA2G4E) is targeted to the membrane compartments of the clathrin-independent endocytic route through a C-terminal stretch of positively charged amino acids, which allows the enzyme to interact with phosphoinositide lipids [especially PI(4,5)P2] that are enriched in clathrin-independent endosomes. Ablation of cPLA2&egr; suppressed the formation of tubular elements that carry internalized clathrin-independent cargoes, such as MHC-I, CD147 and CD55, back to the cell surface and, therefore, caused their intracellular retention. The ability of cPLA2&egr; to support recycling through tubule formation relies on the catalytic activity of the enzyme, because the inactive cPLA2&egr;S420A mutant was not able to recover either tubule growth or transport from clathrin-independent endosomes. Taken together, our findings indicate that cPLA2&egr; is a new important regulator of trafficking processes within the clathrin-independent endocytic and recycling route. The affinity of cPLA2&egr; for this pathway supports a new hypothesis that different PLA2 enzymes use selective targeting mechanisms to regulate tubule formation locally during specific trafficking steps in the secretory and/or endocytic systems.
The Effects of Cognitive Capacity and Suspicion on Truth Bias

This study investigated the effects of cognitive capacity and suspicion on veracity judgments. It was hypothesized that under low suspicion conditions, truth bias would be more pronounced when participants had low cognitive capacity than when participants had high cognitive capacity. One hundred and seven participants viewed presentations of people either truthfully or deceptively describing a series of pictures. Prior to the presentations, a short description designed to increase suspicion was read to half the participants. Participants viewed half of the presentations while working on arithmetic problems (low capacity) and the other half while not working on arithmetic problems (high capacity). Following each presentation, the participants were required to evaluate the communicator's performance on a number of scales and indicate whether the communicator was actually describing the picture. The results partially supported the hypothesis.
Learning Through the Ages? Generational Inequalities and Inter-Generational Dynamics of Lifelong Learning

ABSTRACT This exploratory paper considers the concept of generation in the context of learning across the life course. Although researchers have often found considerable inequalities in participation by age, as well as strongly articulated attitudinal differences, there have so far been only a handful of studies that have explored these patterns through the perspective of generational formations. The paper is primarily conceptual, exploratory and reflective, setting out a number of approaches to the concept of generations, most of which derive largely from debates with the ghost of Karl Mannheim; it then considers how these concepts of generation have been applied to understandings of educational inequalities in recent research in Germany and the Nordic nations. It then examines the dynamics of inter-generational relations in learning, drawing on research undertaken as part of the Teaching and Learning Research Programme. The paper argues that although inter-generational dynamics are a relatively neglected dimension of Anglophone research on life chances and learning, there is a strong case for understanding their dual roles in both inequality and cohesion. It concludes by outlining some themes and areas for further investigation in the future.
In Vitro Evaluation of Biofield Treatment on Cancer Biomarkers Involved in Endometrial and Prostate Cancer Cell Lines

Increasing cancer rates particularly in the developed world are associated with related lifestyle and environmental exposures. Combined immunotherapy and targeted therapies are the main treatment approaches in advanced and recurrent cancer. An alternate approach, energy medicine is increasingly used in life threatening problems to promote human wellness. This study aimed to investigate the effect of biofield treatment on cancer biomarkers involved in human endometrium and prostate cancer cell lines. Each cancer cell lines were taken in two sealed tubes i.e. one tube was considered as control and another tube was subjected to Mr. Trivedi’s biofield treatment, referred as treated. Control and treated samples were studied for the determination of cancer biomarkers such as multifunctional cytokines viz. interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), interleukin-2 receptor (IL-2R), prostate specific antigen (PSA), and free prostate specific antigen (FPSA) concentrations using ELISA assay on day 10. Experimental results showed a significant reduction of IL-6 level in endometrium (12%) and prostate (98.8%) cancer cell lines while a significant increase was observed in TNF-α level in endometrium (385%) and prostate (89.8%) cancer cell lines as compared to control. No alteration of PSA level was observed in biofield treated endometrium and prostate cell line. Similarly, no alterations were evident in IL-2R and FPSA levels in endometrium and prostate cell lines after biofield treatment as compared to control. In conclusion, results suggest that biofield treatment has shown significant alterations in the level of cytokines (IL-6 and TNF-α) in both endometrium and prostate cancer cell lines.
An Integrative Approach for Studying the Etiology of Alcoholism and Other Addictions

Abstract Studies of alcoholism etiology often focus on genetic or psy-chosocial approaches, but not both. Greater understanding of the etiology of alcohol, tobacco and other addictions will come from integration of these research traditions. A research approach is outlined to test three models for the etiology of addictions — behavioral undercontrol, pharmacologic vulnerability, negative affect regulation — addressing key questions including (i) mediators of genetic effects, (ii) genotype-environment correlation effects, (iii) genotype x environment interaction effects, (iv) the developmental unfolding of genetic and environmental effects, (v) subtyping including identification of distinct trajectories of substance involvement, (vi) identification of individual genes that contribute to risk, and (vii) the consequences of excessive use. By using coordinated research designs, including prospective assessment of adolescent twins and their siblings and parents; of adult substance dependent and control twins and their MZ and DZ cotwins, the spouses of these pairs, and their adolescent offspring; and of regular families; by selecting for gene-mapping approaches sibships screened for extreme concordance or discordance on quantitative indices of substance use; and by using experimental (drug challenge) as well as survey approaches, a number of key questions concerning addiction etiology can be addressed. We discuss complementary strengths and weaknesses of different sampling strategies, as well as methods to implement such an integrated approach illustrated for the study of alcoholism etiology. A coordinated program of twin and family studies will allow a comprehensive dissection of the interplay of genetic and environmental risk-factors in the etiology of alcoholism and other addictions.
Workload Modeling for Computer Systems Performance Evaluation

Reliable performance evaluations require the use of representative workloads. This is no easy task since modern computer systems and their workloads are complex, with many interrelated attributes and complicated structures. Experts often use sophisticated mathematics to analyze and describe workload models, making these models difficult for practitioners to grasp. This book aims to close this gap by emphasizing the intuition and the reasoning behind the definitions and derivations related to the workload models. It provides numerous examples from real production systems, with hundreds of graphs. Using this book, readers will be able to analyze collected workload data and clean it if necessary, derive statistical models that include skewed marginal distributions and correlations, and consider the need for generative models and feedback from the system. The descriptive statistics techniques covered are also useful for other domains.