Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictors of depression, stress, and anxiety among non-tenure track faculty

Nationwide in the United States, 70% of faculty members in higher education are employed off the tenure-track. Nearly all of these non-tenure-track (NTT) appointments share a quality that may produce stress for those who hold them: contingency. Most NTT appointments are contingent on budget, enrollment, or both, and the majority of contingent faculty members are hired for one quarter or semester at a time. Significant research has investigated the effects of contingency on teaching, students, departments, colleges, and universities; however, little research has focused on the psychological experiences of NTT faculty. The current study examined perceptions of workplace stressors and harm, organizational commitment, common coping mechanisms, and depression, anxiety and stress among NTT faculty using a longitudinal design that spanned 2–4 months. Results indicate that NTT faculty perceive unique stressors at work that are related to their contingent positions. Specific demographic characteristics and coping strategies, inability to find a permanent faculty position, and commitment to one's organization predispose NTT faculty to perceive greater harm and more sources of stress in their workplaces. Demographic characteristics, lower income, inability to find a permanent faculty position, disengagement coping mechanisms (e.g., giving up, denial), and organizational commitment were associated with the potential for negative outcomes, particularly depression, anxiety, and stress. Our findings suggest possibilities for institutional intervention. Overall, we argue that universities would be well-served by attending to the needs of NTT faculty on campus in order to mitigate negative outcomes for institutions, students, and faculty.
Zoonotic diseases in South American camelids in England and Wales

SUMMARY The number of South American camelids (SACs) in England and Wales is increasing and with this comes a risk of new and emerging infections. Although classified as livestock, these animals are also treated as pets and may be in regular contact with humans. This paper reviews zoonotic diseases that have been identified in SACs in England and Wales, and which pose a potential risk to human health. We also highlight the importance of surveillance continuing to capture information on infections in SACs for the protection of both public and animal health.
Predicting the physiological performance of ectotherms in fluctuating thermal environments

SUMMARY Physiological ecologists have long sought to understand the plasticity of organisms in environments that vary widely among years, seasons and even hours. This is now even more important because human-induced climate change is predicted to affect both the mean and variability of the thermal environment. Although environmental change occurs ubiquitously, relatively few researchers have studied the effects of fluctuating environments on the performance of developing organisms. Even fewer have tried to validate a framework for predicting performance in fluctuating environments. Here, we determined whether reaction norms based on performance at constant temperatures (18, 22, 26, 30 and 34°C) could be used to predict embryonic and larval performance of anurans at fluctuating temperatures (18–28°C and 18–34°C). Based on existing theory, we generated hypotheses about the effects of stress and acclimation on the predictability of performance in variable environments. Our empirical models poorly predicted the performance of striped marsh frogs (Limnodynastes peronii) at fluctuating temperatures, suggesting that extrapolation from studies conducted under artificial thermal conditions would lead to erroneous conclusions. During the majority of ontogenetic stages, growth and development in variable environments proceeded more rapidly than expected, suggesting that acute exposures to extreme temperatures enable greater performance than do chronic exposures. Consistent with theory, we predicted performance more accurately for the less variable thermal environment. Our results underscore the need to measure physiological performance under naturalistic thermal conditions when testing hypotheses about thermal plasticity or when parameterizing models of life-history evolution.
Encoding and Media Effects on Consumer Learning Deficiencies in the Elderly

Alternative cognitive explanations of memory deficiencies in the elderly suggest certain conditions in which elderly might be expected to learn less than younger adults in a consumer information processing context. The authors investigated these conditions using the levels-of-processing framework for the study of memory. The results indicate greater difficulties on the part of the elderly in deeply processing information from print media and in realizing the learning benefits of television. These findings suggest that marketers face unique problems in reaching this increasingly attractive market segment.
On the evolution of random graphs

(n) k edges have equal probabilities to be chosen as the next one . We shall 2 study the "evolution" of such a random graph if N is increased . In this investigation we endeavour to find what is the "typical" structure at a given stage of evolution (i . e . if N is equal, or asymptotically equal, to a given function N(n) of n) . By a "typical" structure we mean such a structure the probability of which tends to 1 if n -* + when N = N(n) . If A is such a property that lim Pn,N,(n ) ( A) = 1, we shall say that „almost all" graphs Gn,N(n) n--possess this property .
Characterization of Spaghetti Prepared Under Different Drying Conditions.

Spaghetti dried at low (max. 50 °C), high (max. 70 °C), and very high (max. 85 °C) temperatures were characterized by their color, surface structure, rupture strength, texture analysis, and sauce retention capacity. The texture and sauce retention capacity were estimated for cooked spaghetti. The color of the spaghetti's methanol extracts, as evaluated through absorbance at 440 and 466 nm, did not depend on the drying temperature. A trend was observed in the surface texture of spaghetti, as estimated by atomic force microscopy and mercury intrusion porosimetry, where the surface was rougher when dried at higher temperatures than at low temperatures. Furthermore, the rupture strength was also higher for the spaghetti dried at higher temperatures. This result can be ascribed to the formation of stronger gluten networks, promoted by denaturation of gluten at the higher temperatures. However, the hardness of cooked spaghetti was not affected by the drying temperature, a result attributable to the action of water sorption to offset any differences in hardness among the spaghettis dried at the 3 different temperatures. The sauce retention capacity of cooked spaghetti was evaluated using a dextran solution as a simulated sauce, and by this method, the capacity of the spaghetti dried at a low temperature was shown to be significantly lower than that of the spaghetti dried at higher temperatures. This can be ascribed to the smoother surface of cooked spaghetti dried at the lower temperature and also to the leakage of amylose onto the surface during cooking.
A national survey of training in substance use disorders in residency programs.

OBJECTIVE To determine the amount of formal training in substance use disorders that occurs in selected residency programs and to identify the perceived barriers to such training. METHOD A national survey was conducted of program directors in emergency medicine, family medicine, internal medicine, obstetrics/gynecology, osteopathic medicine, pediatrics and psychiatry. In 1997, program directors were mailed a brief survey to determine the extent to which required training in substance use disorders occurred and the median number of hours devoted to substance use disorders training. Follow-up telephone surveys were conducted with faculty designated in the survey as responsible for substance-related disorders training to determine type of training and barriers to training. RESULTS Of 1,831 program directors, 1,183 (64.6%) responded to the brief survey. The percentage of programs with required substance use disorders training ranged from 31.8% in pediatrics to 95.0% in psychiatry, with 56.3% for all programs combined. The median number of curricular hours ranged from 3 (emergency medicine and OB/GYN) to 12 (family medicine). Time was perceived to be the most common barrier to additional training. CONCLUSIONS Consistent training for all residents in the initial diagnosis and management of substance use disorders has not been achieved. New strategies that integrate into existing residency structures are needed to improve substance use disorders training. Faculty development in substance use disorders and review of current substance use disorders training as part of the residency review process should facilitate this endeavor.
Relationship between the Presence of Bartonella Species and Bacterial Loads in Cats and Cat Fleas (Ctenocephalides felis) under Natural Conditions

ABSTRACT Cats are considered the main reservoir of three zoonotic Bartonella species: Bartonella henselae, Bartonella clarridgeiae, and Bartonella koehlerae. Cat fleas (Ctenocephalides felis) have been experimentally demonstrated to be a competent vector of B. henselae and have been proposed as the potential vector of the two other Bartonella species. Previous studies have reported a lack of association between the Bartonella species infection status (infected or uninfected) and/or bacteremia levels of cats and the infection status of the fleas they host. Nevertheless, to date, no study has compared the quantitative distributions of these bacteria in both cats and their fleas under natural conditions. Thus, the present study explored these relationships by identifying and quantifying the different Bartonella species in both cats and their fleas. Therefore, EDTA-blood samples and fleas collected from stray cats were screened for Bartonella bacteria. Bacterial loads were quantified by high-resolution melt real-time quantitative PCR assays. The results indicated a moderate correlation between the Bartonella bacterial loads in the cats and their fleas when both were infected with the same Bartonella species. Moreover, a positive effect of the host infection status on the Bartonella bacterial loads of the fleas was observed. Conversely, the cat bacterial loads were not affected by the infection status of their fleas. Our results suggest that the Bartonella bacterial loads of fleas are positively affected by the presence of the bacteria in their feline host, probably by multiple acquisitions/accumulation and/or multiplication events.
The dissolution of paracetamol tablets and the in vitro transfer of paracetamol with and without sorbitol

MANY adjuvants such as sorbitol, glucosamine hydrochloride and sodium hexametaphosphate, have been added to oral dosage forms to improve the absorption of drugs, but Wagner (1961) emphasizes that the attribution of beneficial results to them is not always unequivocal. With sorbitol in paracetamol tablets, it has been suggested that the improved absorption is due to the sorbitol acting on the metabolism of paracetamol and as a dispersing agent (Gwilt, Robertson & others, 1963). The combination of paracetamol and sorbitol provides a readily assayable system with which to examine the role of the adjuvant.
An Asymptotic Analysis of the Spatially Inhomogeneous Velocity-Jump Process

We analyze the one-dimensional velocity-jump process, where a particle moves at a constant velocity determined by the particle’s internal velocity state that randomly fluctuates with exponentially distributed waiting times. The transition rates between the internal velocity states depend on the location of the particle, leading to a spatially inhomogeneous random process. An asymptotic analysis is applied to obtain the stationary distribution of the random process. The result is compared to the often-used quasi–steady-state diffusion approximation, and it is found that the diffusion approximation breaks down in the presence of a turning point, where the average velocity of the particle changes sign. We extend the analysis to approximate the first-exit time density for the particle to escape the confining effect of the turning point, and we find the diffusion approximation also fails to accurately describe the long-time behavior of the process. The accuracy of the two approximations is explored for a simpl.
Chromosome 8p alterations in sporadic andBRCA2 999del5 linked breast cancer

Chromosomal losses involving the short arm of chromosome 8 are frequent in a variety of tumour types, including breast cancer, suggesting the presence of one or more tumour suppressor genes in this region. In this study, we have used 11 microsatellite markers to analyse loss of heterozygosity (LOH) at chromosome 8p in 151 sporadic breast tumours and 50 tumours from subjects carrying theBRCA2 999del5 mutation. Fifty percent of sporadic tumours compared to 78% of BRCA2linked tumours exhibit LOH at one or more markers at 8p showing that chromosome 8p alterations in breast tumours fromBRCA2 999del5 carriers are more pronounced than in sporadic breast tumours. The pattern of LOH is different in the two groups and a higher proportion of BRCA2tumours have LOH in a large region of chromosome 8p. In the total patient material, LOH of 8p is associated with LOH at other chromosome regions, for example, 1p, 3p, 6q, 7q, 9p, 11p, 13q, 17p, and 20q, but no association is found between LOH at 8p and chromosome regions 11q, 16q, 17q, and 18q. Furthermore, an association is detected between LOH at 8p and positive node status, large tumour size, aneuploidy, and high S phase fraction. Breast cancer patients with LOH at chromosome 8p have a worse prognosis than patients without this defect. Multivariate analysis suggests that LOH at 8p is an independent prognostic factor. We conclude that chromosome 8p carries a tumour suppressor gene or genes, the loss of which results in growth advantage of breast tumour cells, especially in carriers of the BRCA2999del5 mutation.
Do Private Equity-owned Firms Have Better Management Practices?

Using an innovative survey measure of management practices on over 15,000 firms, we find private equity firms are better managed than government, family, and privately owned firms, and have similar management to publicly listed firms. This is true both in developed and developing countries. Looking at management practices in detail we find that private equity owned firms have strong people management practices (hiring, firing, pay, and promotions), but even stronger monitoring management practices (lean manufacturing, continuous improvement, and monitoring). Plant managers working in private equity owned firms also report greater autonomy from headquarters over sales, marketing, and new product introduction.
Postnatal Development of Dendrodendritic Inhibition in the Mammalian Olfactory Bulb

The mitral–granule cell (MC–GC) reciprocal synapse is an important source of auto- and lateral-inhibition in the olfactory bulb (OB), and this local inhibition is critical for odor discrimination. We may gain insight into the role of MC autoinhibition in olfaction by correlating the functional development of the autoinhibition with the postnatal development of olfactory function. We have studied the functional development of the MC–GC reciprocal synapse using whole-cell patch-clamp recordings from MCs and GCs in acute OB slices from 3- to 30-day-old rats. The magnitude of dendrodendritic inhibition (DDI) measured by depolarizing a single MC and recording recurrent inhibition in the same cell increased up to the fifteenth day of life (P15), but dropped between P15 and P30. The initial increase and later decrease in DDI was echoed by a similar increase and decrease in the frequency of miniature inhibitory post-synaptic currents, suggesting an accompanying modulation in the number of synapses available to participate in DDI. The late decrease in DDI could also result, in part, from a decrease in GC excitability as well as an increase in relative contribution of N-methyl d-aspartate (NMDA) receptors to γ-amino butyric acid (GABA) release from GC synapses. Changes in release probability of GABAergic synapses are unlikely to account for the late reduction in DDI, although they might contribute to the early increase during development. Our results demonstrate that the functional MC–GC circuit evolves over development in a complex manner that may include both construction and elimination of synapses.
Efficient metrics and high-level synthesis for dynamically reconfigurable logic

The increase in complexity of programmable hardware platforms results in the need to develop efficient high-level synthesis (HLS) tools since it allows more efficient exploration of the design space while predicting the effects of technology specific tools on the design space. Much of the previous works however neglect the delay of interconnects (e.g. multiplexer) which can indeed contribute heavily on the overall performance of the design. In addition, in the case of dynamic reconfigurable logic (DRL) circuits, unless an appropriate design methodology is followed, large number of configurable logic blocks (CLBs) could be used for communication between contexts, rather than for implementing functional units (FUs). The aim of this paper is to present a new technique to perform interconnect-sensitive synthesis, targeting dynamic reconfigurable circuits. Further, the proposed technique exploits multiple hardware contexts to achieve efficient designs. Experimental results on several benchmarks, which have been done on our DRL LSI circuit (Meribout, 2000 and Motomura, 1997), demonstrate that by jointly optimizing the interconnect, communication, and function-unit cost, higher quality designs than other previous techniques (e.g. force-directed scheduling) can be achieved.
GENETIC VARIATION IN MALE EFFECTS ON FEMALE REPRODUCTION AND THE GENETIC COVARIANCE BETWEEN THE SEXES

Abstract Males of many insect species increase the fecundity and/or egg size of their mates through the amount or composition of their nuptial gifts or ejaculate. The genetic bases of such male effects on fecundity or egg size are generally unknown, and thus their ability to evolve remains speculative. Likewise, the genetic relationship between male and female investment into reproduction in dioecious species, which is expected to be positive if effects on fecundity are controlled by at least some of the same genes in males and females, is also unknown. Males of the seed beetle Stator limbatus contribute large ejaculates to females during mating, and the amount of donated ejaculate is positively correlated with male body mass. Females mated to large males lay more eggs in their lifetime than females mated to small males. We describe an experiment in which we quantify genetic variation in the number of eggs sired by males (mated to a single female) and found that a significant proportion of the phenotypic variance in the number of eggs sired by males was explained by their genotype. Additionally, the number of eggs sired by a male was highly positively genetically correlated with his body mass. The between-sex genetic correlation, that is, the genetic correlation between the number of eggs sired by males and the number of eggs laid by females, was highly positive when eggs were laid on Acacia greggii seeds. This indicates that males that sire many eggs have sisters that lay many eggs. Thus, some of the genes that control male ejaculate size (or some other fecundity-enhancing factor) when expressed in males appear to control fecundity when expressed in females. We found no significant interaction between male and female genotype on fecundity.
Impact of renal function on eligibility for chemotherapy and survival in patients who have undergone radical nephro‐ureterectomy

Radical nephroureterectomy (RNU), the standard of care treatment for high‐risk urothelial carcinoma of the upper tract (UTUC), results in loss of a renal unit. Loss of renal function decreases eligibility for systemic chemotherapies and results in decreased overall survival in various malignancies. The study shows that only a small proportion of patients had a preoperative renal function that would allow cisplatin‐based chemotherapy. Moreover, eGFR significantly decreased after RNU, thereby lowering the rate of cisplatin eligibility to only 16 and 52% of patients based on the thresholds of 60 and 45 mL/min/1.73 m2, respectively. Taken together with the rest of the literature, the findings of the study support the use of cisplatin‐based chemotherapy, when indicated, in the neoadjuvant rather than adjuvant setting.
Augmenting the conservation value of rehabilitated wildlife by integrating genetics and population modeling in the post-rehabilitation decision process

Abstract Insular populations are particularly vulnerable to the effects of stochastic events, epidemics, and loss of genetic diversity due to inbreeding and genetic drift. The development of successful management options will require accurate baseline data, establishment of clear objectives, and finally monitoring and implementation of corrective measures, if and when required. This study assessed management options for the genetic rehabilitation of highly inbred woylies obtained from wildlife rehabilitation centers. The study generated genetic data for the woylie Bettongia penicillata from a conservation reserve and calculated measures of genetic diversity and individual relatedness. These data were fed into a population viability analysis (PVA) to test genetic outcomes in relation to different management actions. We demonstrated that a careful selection of the founder cohort produced a population with an expected heterozygosity of ∼70% for a window of approximately 10 years. A proposal to increase the size of the reserve available to the colony was shown to almost double the time at which the colony would retain heterozygosity levels of ≥ 70%. Additionally, developing a regular program of supplementation of unrelated woylies would result in a further improvement in their genetic value. This study demonstrated how the application of molecular techniques in combination with PVA can be beneficial for the management of rehabilitated wildlife otherwise considered of little conservation value. This approach can be applied to the management of breeding programs, but also to small, closed populations such as those found on islands, fenced enclosures, insurance populations, and in zoological collections.
Enhancing the implementation of Occupational Health and Safety interventions through a design of the socio-technical interaction

: A multitude of Occupational Health and Safety (OHS) interventions have proven to be effective under controlled conditions, but their implementation in practice is often difficult and interventions may therefore not work as expected, especially when referring to Small and Medium sized Enterprises (SMEs). In order to solve this challenge, this paper proposes a model for the systematic design of OHS interventions which takes into account the underlying mechanisms and the contextual factors which can hamper or further the implementation of interventions.