Miracle-dz/UniFAR-FTUs huggingface dataset:
EXPLAINING SATISFACTION IN DOUBLE DEVIATION SCENARIOS: THE EFFECTS OF ANGER AND DISTRIBUTIVE JUSTICE

Research has shown that more than half of attempted recovery efforts only reinforce dissatisfaction, producing a ‘double deviation’ effect. Surprisingly, these double deviation effects have received little attention in service marketing literature. Yet no study has specifically investigated which are the main determinants of the formation of customer satisfaction judgments in double deviation contexts. To fill this gap, we develop and empirically test a model based on the existing service recovery literature. Specifically, we focus on two theoretical frameworks: social justice theory and theories of emotion. We examine the effect of anger with service recovery on satisfaction with service recovery, as well as the role of distributive justice on the elicitation of the specific emotion of anger with service recovery and satisfaction with service recovery. Results support the model and highlight the important role of specific recovery-related emotions in double deviation contexts. Implications for practice and future research are discussed. La investigacion previa ha mostrado que mas de la mitad de los esfuerzos de recuperacion solo refuerzan la insatisfaccion, produciendo un efecto de desviacion doble. Sorprendentemente, estos efectos de desviacion doble han recibido muy poca atencion en la literatura de marketing de servicios. Hasta la fecha, ningun trabajo ha investigado empiricamente cuales son los principales determinantes en la formacion de los juicios de satisfaccion en contextos de desviacion doble. Para cubrir este hueco, desarrollamos y analizamos empiricamente un modelo basado en la literatura de recuperacion de servicios existente. Especificamente, nos basamos en dos esquemas conceptuales: la teoria de la justicia social y las teorias sobre emociones. Examinamos el efecto del enfado con la recuperacion del servicio en la satisfaccion con la recuperacion del servicio, asi como el papel de la justicia distributiva como activador de emociones especificas de enfado y como antecedente de la satisfaccion con la recuperacion del servicio. Los resultados confirman el modelo propuesto y ponen de manifiesto el importante papel de las emociones especificas relacionadas con la recuperacion en contextos de desviacion doble. Finalmente, se discuten las implicaciones de gestion y las lineas futuras de investigacion.
Separating Microstructure Noise from Volatility

There are two volatility components embedded in the returns constructed using recorded stock prices: the genuine time-varying volatility of the unobservable returns that would prevail (in equilibrium) in a frictionless, full-information, economy and the variance of the equally unobservable microstructure noise. Using straightforward sample averages of high-frequency return data recorded at different frequencies, we provide a simple technique to identify both volatility features. We apply our methodology to a sample of S&P100 stocks.
Multiparty Communication Complexity of Disjointness

We obtain a lower bound of Ω ( n 1 k+1 22 (k−1)2k−1 ) on the k-party randomized communication complexity of the Disjointness function in the ‘Number on the Forehead’ model of multiparty communication. In particular, this yields a bound of n when k is a constant. The previous best lower bound for three players until recently was Ω(logn). Our bound separates the communication complexity classes NP k and BPP k for k = o(log log n). Furthermore, by the results of Beame, Pitassi and Segerlind [4], our bound implies proof size lower bounds for tree-like, degree k − 1 threshold systems and superpolynomial size lower bounds for Lovasz-Schrijver proofs. Sherstov [16] recently developed a novel technique to obtain lower bounds on two-party communication using the approximate polynomial degree of boolean functions. We obatin our results by extending his technique to the multi-party setting using ideas from Chattopadhyay [8]. A similar bound for Disjointness has been recently and independently obtained by Lee and Shraibman.
Predictive Value of Testing Nasopharyngeal Samples for Respiratory Viruses in the Setting of Lower Respiratory Tract Disease

ABSTRACT To determine the predictive value of nasopharyngeal (NP) sample testing for respiratory viruses (RVs) in suspected lower respiratory tract disease, 72 paired NP and bronchoalveolar lavage (BAL) fluid specimen sets, mostly from transplant recipients or patients with hematologic malignancies, were analyzed. Overall, 31.3% of the specimens tested positive for an RV. In 19 sets (26.4%), the NP and BAL fluid specimens were both positive for an RV; in 3 sets (4.2%), the NP specimens were positive but the BAL fluid specimens were negative; and in 3 other sets, the NP specimens were negative but the BAL fluid specimens were positive. The positive and negative predictive values of the NP specimens were 86.4% and 94%, respectively.
Postabortion Doppler Evaluation of the Uterus

Objective. The aim of this study was to investigate the incidence and causes of uterine hypervascular lesions showing low‐impedance, high‐velocity flow on color Doppler sonography (CDS) after first‐trimester dilation and curettage (D&C). Methods. This was a prospective study of 65 consecutive women who underwent first‐trimester termination of pregnancy. Color Doppler sonography of the uterus was performed on days 3 and 10 after D&C. If the myometrial hypervascularity (MH) persisted on day 10, a second D&C was performed, and then the patients were followed with weekly Doppler examinations. Results. In 16 of 65 women (24.6%), MH was detected with CDS on day 3 after D&C. In 3 cases, MH resolved spontaneously by postabortion day 10. In the remaining 13 patients, the second D&C performed on day 10 revealed retained products of conception (RPOC) in 8 patients (61.5%), a hydatidiform mole in 2 (15.4%), endometritis in 1 (7.7%), and no abnormality in 2 (15.4%). Complete resolution of the MH occurred in all cases. The mean period to the resolution of MH after the second D&C ± SD was 16.54 ± 11.06 days (range, 7–48 days). Univariate analysis revealed that gestational age at D&C (P = .012) and a history of any uterine surgery (P = .044) were significantly associated with postabortion MH. On binary logistic regression analysis, gestational age at D&C was the only independent predictive factor for MH (P = .016; odds ratio, 1.47; 95% confidence interval, 1.08–2.02). Conclusions. The presence of hypervascular areas within the myometrium is a common finding in the postabortion period, and in most cases, the cause of this finding is RPOC.
Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

Neurofilaments are transported through axons by slow axonal transport. Abnormal accumulations of neurofilaments are seen in several neurodegenerative diseases, and this suggests that neurofilament transport is defective. Excitotoxic mechanisms involving glutamate are believed to be part of the pathogenic process in some neurodegenerative diseases, but there is currently little evidence to link glutamate with neurofilament transport. We have used a novel technique involving transfection of the green fluorescent protein–tagged neurofilament middle chain to measure neurofilament transport in cultured neurons. Treatment of the cells with glutamate induces a slowing of neurofilament transport. Phosphorylation of the side-arm domains of neurofilaments has been associated with a slowing of neurofilament transport, and we show that glutamate causes increased phosphorylation of these domains in cell bodies. We also show that glutamate activates members of the mitogen-activated protein kinase family, and that these kinases will phosphorylate neurofilament side-arm domains. These results provide a molecular framework to link glutamate excitotoxicity with neurofilament accumulation seen in some neurodegenerative diseases.
Diffusion limits of the random walk metropolis algorithm in high dimensions

Diffusion limits of MCMC methods in high dimensions provide a useful theoretical tool for studying computational complexity. In particular, they lead directly to precise estimates of the number of steps required to explore the target measure, in stationarity, as a function of the dimension of the state space. However, to date such results have mainly been proved for target measures with a product structure, severely limiting their applicability. The purpose of this paper is to study diffusion limits for a class of naturally occurring high-dimensional measures found from the approximation of measures on a Hilbert space which are absolutely continuous with respect to a Gaussian reference measure. The diffusion limit of a random walk Metropolis algorithm to an infinite-dimensional Hilbert space valued SDE (or SPDE) is proved, facilitating understanding of the computational complexity of the algorithm.
Differential relationships between habitat fragmentation and within-population genetic diversity of three forest-dwelling birds

Habitat fragmentation is a major driver of environmental change affecting wildlife populations across multiple levels of biological diversity. Much of the recent research in landscape genetics has focused on quantifying the influence of fragmentation on genetic variation among populations, but questions remain as to how habitat loss and configuration influences within-population genetic diversity. Habitat loss and fragmentation might lead to decreases in genetic diversity within populations, which might have implications for population persistence over multiple generations. We used genetic data collected from populations of three species occupying forested landscapes across a broad geographic region: Mountain Chickadee (Poecile gambeli; 22 populations), White-breasted Nuthatch (Sitta carolinensis; 13 populations) and Pygmy Nuthatch (Sitta pygmaea; 19 populations) to quantify patterns of haplotype and nucleotide diversity across a range of forest fragmentation. We predicted that fragmentation effects on genetic diversity would vary depending on dispersal capabilities and habitat specificity of the species. Forest aggregation and the variability in forest patch area were the two strongest landscape predictors of genetic diversity. We found higher haplotype diversity in populations of P. gambeli and S. carolinensis inhabiting landscapes characterized by lower levels of forest fragmentation. Conversely, S. pygmaea demonstrated the opposite pattern of higher genetic diversity in fragmented landscapes. For two of the three species, we found support for the prediction that highly fragmented landscapes sustain genetically less diverse populations. We suggest, however, that future studies should focus on species of varying life-history traits inhabiting independent landscapes to better understand how habitat fragmentation influences within-population genetic diversity.
Comprehensive Metabolomic Analysis in Blood, Urine, Fat, and Muscle in Men with Metabolic Syndrome: A Randomized, Placebo-Controlled Clinical Trial on the Effects of Resveratrol after Four Months’ Treatment

Resveratrol possesses several beneficial metabolic effects in rodents, while the effects of resveratrol in humans remain unclear. Therefore, we performed a non-targeted comprehensive metabolomic analysis on blood, urine, adipose tissue, and skeletal muscle tissue in middle-aged men with metabolic syndrome randomized to either resveratrol or placebo treatment for four months. Changes in steroid hormones across all four matrices were the most pronounced changes observed. Resveratrol treatment reduced sulfated androgen precursors in blood, adipose tissue, and muscle tissue, and increased these metabolites in urine. Furthermore, markers of muscle turnover were increased and lipid metabolism was affected, with increased intracellular glycerol and accumulation of long-chain saturated, monounsaturated, and polyunsaturated (n3 and n6) free fatty acids in resveratrol-treated men. Finally, urinary derivatives of aromatic amino acids, which mainly reflect the composition of the gut microbiota, were altered upon resveratrol treatment. In conclusion, the non-targeted metabolomics approach applied to four different matrices provided evidence of subtle but robust effects on several metabolic pathways following resveratrol treatment for four months in men with metabolic syndrome—effects that, for the most part, would not have been detected by routine analyses. The affected pathways should be the focus of future clinical trials on resveratrol’s effects, and perhaps particularly the areas of steroid metabolism and the gut microbiome.
Current and future treatment options for esophageal cancer in the elderly

ABSTRACT Introduction: Esophageal cancer is the eighth most common cancer globally and has the sixth worst prognosis because of its aggressiveness and poor survival. Data regarding cancer treatment in older patients is limited because the elderly have been under-represented in clinical trials. Therefore, we reviewed the existing literature regarding treatment results for elderly patients (70+ years). Areas covered: We used pubmed to analyze the actual literature according to elderly esophageal cancer patients with subheading of incidence, esophagectomy, chemoradiation or chemotherapy. The main points of interest were treatment options for patients with Barrett’s esophagus or early carcinoma, advanced tumor stages, and inoperable cancer. Expert opinion: The incidence of esophageal cancer has been increasing over the past thirty years, with a rapid increase of esophageal adenocarcinoma in Western industrialized nations. Patients aged over 60 years have been particularly affected. In this review, we have shown that elderly patients with esophageal cancer have various alternatives for adequate treatment. Clinical evaluation of comorbidity is necessary to make treatment decisions. Therapeutic options for early carcinomas are endoscopic or surgical resection. For elderly patients with advanced carcinomas, preoperative chemoradiation or chemotherapy should be discussed.
Association between cultural factors and the caregiving burden for Chinese spousal caregivers of frail elderly in Hong Kong

Objectives: The aim of this study was to explore the relationship between cultural factors and the caregiving burden of Chinese spousal caregivers who provided care to their frail partners. Method: A sample consisting of 102 Chinese caregivers for frail elderly spouses was recruited from home care services across various districts in Hong Kong. Structured interviews were conducted with the participants in their homes, measuring demographics, the functional status of the spouse, the degree of assistance required in daily care, perceived health, the caregiver's orientation to traditional Chinese family values, social support, coping, and caregiver burden. Results: Findings of regression analysis indicated that gender, activities of daily living (ADL) status, orientation to traditional Chinese family values, passive coping, and marital satisfaction associated with caregiver burden. Being female, having lower functioning in ADL or a strong orientation toward traditional Chinese family values, employing the strategies of passive coping more frequent, or experiencing a low degree of marital satisfaction were associated with high levels of caregiver burden. Conclusion: These findings provided a basis for developing appropriate interventions to minimize the caregiver burden of spousal family caregivers.
Role of adhesion molecules and dendritic cells in rat hepatic/renal ischemia-reperfusion injury and anti-adhesive intervention with anti-P-selectin lectin-EGF domain monoclonal antibody.

AIM To investigate the role of P-selectin, intercellular adhesion molecule-1 (ICAM-1) and dendritic cells (DCs) in liver/kidney of rats with hepatic/renal ischemia-reperfusion injury and the preventive effect of anti-P-selectin lectin-EGF domain monoclonal antibody (anti-PsL-EGFmAb) on the injury. METHODS Rat models of hepatic and renal ischemia-reperfusion were established. The rats were then divided into two groups, one group treated with anti-PsL-EGFmAb (n = 20) and control treated with saline (n = 20). Both groups were subdivided into four groups according to reperfusion time (1, 3, 6 and 24 h). The sham-operated group (n = 5) served as a control group. DCs were observed by the microscopic image method, while P-selectin and ICAM-1 were analyzed by immunohistochemistry. RESULTS P-selectin increased significantly in hepatic sinusoidal endothelial cells and renal tubular epithelial cells 1 h after ischemia-reperfusion, and the expression of ICAM-1 was up-regulated in hepatic sinusoid and renal vessels after 6 h. CD1a(+)CD80(+)DCs gradually increased in hepatic sinusoidal endothelium and renal tubules and interstitium 1 h after ischemia-reperfusion, and there was the most number of DCs in 24-h group. The localization of DCs was associated with rat hepatic/renal function. These changes became less significant in rats treated with anti-PsL-EGFmAb. CONCLUSION DCs play an important role in immune pathogenesis of hepatic/renal ischemia-reperfusion injury. Anti-PsL-EGFmAb may regulate and inhibit local DC immigration and accumulation in liver/kidney.
Drosophila as a model system to unravel the layers of innate immunity to infection

Summary Innate immunity relies entirely upon germ-line encoded receptors, signalling components and effector molecules for the recognition and elimination of invading pathogens. The fruit fly Drosophila melanogaster with its powerful collection of genetic and genomic tools has been the model of choice to develop ideas about innate immunity and host–pathogen interactions. Here, we review current research in the field, encompassing all layers of defence from the role of the microbiota to systemic immune activation, and attempt to speculate on future directions and open questions.
On the XML Data Stream and Xpath Queries

With the growing importance of XML in data exchange, much research has been done in providing flexible query mechanisms to extract data from XML documents. In this paper, we focus on the query evaluation in an XML streaming environment, in which data streams arrive continuously and queries have to be evaluated even before all the data of an XML document is available. We will propose an algorithm for this issue, working in O(|T|⋅Qleaf) time and O(|T|⋅Qleaf) space, where Tleaf stands for the number of the leaf nodes in a document tree T and Qleaf for the number of the leaf nodes in a query tree Q.
Epistasis and genotype-by-environment interaction of grain protein content in durum wheat

Parental, F1 , F 2 , BC 1 and BC 2 generations of four crosses involving four cultivars of durum wheat (Triticum durum Desf.) were evaluated at two sites in Tunisia. A three-parameter model was found inadequate for all cases except crosses Chili x Cocorit 71 at site Sidi Thabet and Inrat 69 x Karim at both sites. In most cases a digenic epistatic model was sufficient to explain variation in generation means. Dominance effects (h) and additive x additive epistasis (i) (when significant) were more important than additive (d) effects and other epistatic components. Considering the genotype-by-environment interaction, the non-interactive model (m, d, h, e) was found adequate. Additive variance was higher than environmental variance in three crosses at both sites. The estimated values of narrow-sense heritability were dependent upon the cross and the sites and were 0%-85%. The results indicate that appropriate choice of environment and selection in later generations would increase grain protein content in durum wheat.
Signal Transduction Underlying Carbachol-Induced Contraction of Rat Urinary Bladder. I. Phospholipases and Ca2+ Sources

We have reexamined the muscarinic receptor subtype mediating carbachol-induced contraction of rat urinary bladder and investigated the role of phospholipase (PL)C, D, and A2 and of intra- and extracellular Ca2+ sources in this effect. Based on the nonsubtype-selective tolterodine, the highly M2 receptor-selective (R)-4-{2-[3-(4-methoxy-benzoylamino)-benzyl]-piperidin-1-ylmethyl}-piperidine-1-carboxylic acid amide (Ro-320-6206), and the highly M3 receptor-selective darifenacin and 3-(1-carbamoyl-1,1-diphenylmethyl)-1-(4-methoxyphenylethyl)pyrrolidine (APP), contraction occurs via M3 receptors. Carbachol stimulated inositol phosphate formation in rat bladder slices, and this was abolished by the phospholipase C inhibitor 1-(6-[([17β]-3-methoxyestra-1,3,5[10]-trien-17-yl)-amino]hexyl)-1H-pyrrole-2,5-dione (U 73,122; 10 μM). Nevertheless, U 73,122 (1–10 μM) did not significantly affect carbachol-stimulated bladder contraction. Carbachol had only little effect on PLD activity in bladder slices, but the PLD inhibitor butan-1-ol, relative to its negative control butan-2-ol (0.3% each), caused detectable inhibition of carbachol-induced bladder contraction. The cytosolic PLA2 inhibitor arachidonyltrifluoromethyl ketone weakly inhibited carbachol-induced contraction at a concentration of 300 μM, but the cyclooxygenase inhibitor indomethacin (1–10 μM) remained without effect. The Ca2+ entry blocker nifedipine (10–100 nM) almost completely inhibited carbachol-induced bladder contraction. In contrast, 1-[β-[3-(4-methoxyphenyl)propoxy]-4-methoxyphenethyl]-1H-imidazole HCl (SKF 96,365; 10 μM), an inhibitor of store-operated Ca2+ channels, caused little inhibition. We conclude that carbachol-induced contraction of rat bladder largely depends on Ca2+ entry through nifedipine-sensitive channels and, perhaps, PLD, PLA2, and store-operated Ca2+ channels, whereas cyclooxygenase and, surprisingly, also PLC are not involved to a relevant extent.
CONDESA: A Framework for Controlling Data Distribution on Elastic Server Architectures

Applications running in today's data centers show high workload variability. While seasonal patterns, trends and expected events may help building proactive resource allocation policies, this approach has to be complemented with adaptive strategies which should address unexpected events such as flash crowds and volume spikes. Additionally, the limitations of current I/O infrastructures in the face of dramatic increase of data generation require, the ability to build novel abstractions and models for robust decision making regarding data layout and data locality. In this work, we present CONDESA (CONtrolling Data distribution on Elastic Server Architectures), a framework for exploring adaptive data distribution strategies for elastic server architectures. To the best of our knowledge CONDESA is the first platform that permits to systematically study the interplay between five data related strategies: workload prediction, adaptive control of data distribution and server provisioning, adaptive data grouping, adaptive data placement, and adaptive system sizing. We demonstrate how CONDESA can be used for browsing the design space of adaptive data distribution policies. We show how prediction models can be compared in terms of overhead and accuracy. We evaluate the impact of change detection on prediction accuracy and how CONDESA can be used for choosing an adequate prediction horizon. We demonstrate how adaptive prediction can be used for sizing a server system. Finally, we show how prediction models, change detection strategies, and data placement policies can be combined and compared based on server utilization, load balance, data locality, over- and underprovisioning.