Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychophysiological responses in women with premenstrual and menstrual symptoms

The hypothesis was tested that women reporting symptom disturbances during the menstrual and premenstrual phases would show increased psychophysiological responses to experimental tasks during these cycle phases. Thirty-three nulliparous women with a history of regular cycles who differed in symptom severity during the menstrual cycle were allocated on the basis of daily symptom ratings to three groups: a paramenstrual symptom group (n=12); a menstrual symptom group (n=12) and a symptom-free control group (n=9). None had sought treatment for premenstrual tension or were taking oral contraceptives. Each was tested experimentally in a counterbalanced design during the premenstrual, menstrual and postmenstrual phases while completing a second daily symptom diary. Heart rate, skin conductance level, muscle tension and respiration rate and volume were monitored during rest, and exposure to four experimental tasks designed to elicit appropriate affective responses. Variations in resting level of heart rate and respiration rate were observed, with the highest levels in the premenstrual phase. Skin conductance and respiratory volume reactions to tasks also differed across groups and cycle phases. However, premenstrual and menstrual symptoms were not associated with marked changes in autonomic activity. Possible explanations for these results are discussed.
Studying the WHIM with Gamma Ray Bursts

We assess the possibility to detect and characterize the physical state of the missing baryons at low redshift by analyzing the X-ray absorption spectra of the Gamma Ray Burst [GRB] afterglows, measured by a micro calorimeters-based detector with 3 eV resolution and 1000 cm2 effective area and capable of fast re-pointing, similar to that on board of the recently proposed X-ray satellites EDGE and XENIA. For this purpose we have analyzed mock absorption spectra extracted from different hydrodynamical simulations used to model the properties of the Warm Hot Intergalactic Medium [WHIM]. These models predict the correct abundance of OVI absorption lines observed in UV and satisfy current X-ray constraints. According to these models space missions like EDGE and XENIA should be able to detect about 60 WHIM absorbers per year through the OVII line. About 45 % of these have at least two more detectable lines in addition to OVII that can be used to determine the density and the temperature of the gas. Systematic errors in the estimates of the gas density and temperature can be corrected for in a robust, largely model-independent fashion. The analysis of the GRB absorption spectra collected in three years would also allow to measure the cosmic mass density of the WHIM with about 15 % accuracy, although this estimate depends on the WHIM model. Our results suggest that GRBs represent a valid, if not preferable, alternative to Active Galactic Nuclei to study the WHIM in absorption. The analysis of the absorption spectra nicely complements the study of the WHIM in emission that the spectrometer proposed for EDGE and XENIA would be able to carry out thanks to its high sensitivity and large field of view.
Study on Online Banking Adoption and Its Predictors

The paper develops earlier work on the factors that influence user acceptance of online banking. Given that previous work has demonstrated this with the relatively weak explanatory power of simple and unitary dimension, the research brings together constructs including user satisfaction, performance expectancy, effort expectancy, social influence and self-efficacy to get a comprehensive understanding. This paper proposes an integrated model to analyze and predict user adoption. Moreover, the model considers various aspects of user satisfaction in regard to system quality, information quality and service quality of an information system (IS). On top of that, this paper provides an empirical test of the model. The results of data analysis are then presented. Finally, the paper concludes with a discussion of the corresponding managerial implications.
Market Fluctuations , Trading Activity , and the Cross-Section of Expected Stock Returns

Book/Market Fluctuations, Trading Activity, and the Cross-Section of Expected Stock Returns We analyze trading activity accompanying equities’ switches from “growth” (low book-to-market ratios) to “value” (high book-to-market ratios), and vice versa. We find that a large book/market ratio increase, i.e., a shift from growth to value, is accompanied by a strongly negative small order imbalance. Large order imbalance exhibits weaker patterns across stocks that experience large changes in book/market. The evidence indicates that growth-to-value shifts are more strongly related to small traders than large ones. The interaction of book/market ratios with order flows plays a crucial role in return predictability. Specifically, the predictive ability of book/market ratios for future returns is significantly enhanced for those stocks that have experienced book/market increases as well as high levels of net selling by way of small orders.
A 13-Gene Signature Prognostic of HPV-Negative OSCC: Discovery and External Validation

Purpose: To identify a prognostic gene signature for patients with human papilloma virus (HPV)–negative oral squamous cell carcinomas (OSCC). Experimental Design: Two gene expression datasets were used: a training dataset from the Fred Hutchinson Cancer Research Center (FHCRC, Seattle, WA; n = 97) and a validation dataset from the MD Anderson Cancer Center (MDACC, Houston, TX; n = 71). We applied L1/L2-penalized Cox regression models to the FHCRC data on the 131-gene signature previously identified to be prognostic in patients with OSCCs to identify a prognostic model specific for patients with high-risk HPV-negative OSCCs. The models were tested with the MDACC dataset using a receiver operating characteristic (ROC) analysis. Results: A 13-gene model was identified as the best predictor of HPV-negative OSCC-specific survival in the training dataset. The risk score for each patient in the validation dataset was calculated from this model and dichotomized at the median. The estimated 2-year mortality (±SE) of patients with high-risk scores was 47.1% (±9.24%) compared with 6.35% (±4.42) for patients with low-risk scores. ROC analyses showed that the areas under the curve for the age, gender, and treatment modality-adjusted models with risk score [0.78; 95% confidence interval (CI), 0.74–0.86] and risk score plus tumor stage (0.79; 95% CI, 0.75–0.87) were substantially higher than for the model with tumor stage (0.54; 95% CI, 0.48–0.62). Conclusions: We identified and validated a 13-gene signature that is considerably better than tumor stage in predicting survival of patients with HPV-negative OSCCs. Further evaluation of this gene signature as a prognostic marker in other populations of patients with HPV-negative OSCC is warranted. Clin Cancer Res; 19(5); 1197–203. ©2012 AACR.
Modeling Simple Decisions and Applications Using a Diffusion Model

The diffusion model is one of the major sequential-sampling models for two-choice decision-making and choice response time in psychology. The model conceives of decision-making as a process in which noisy evidence is accumulated until one of two response criteria is reached and the associated response is made. The criteria represent the amount of evidence needed to make each decision and reflect the decision maker’s response biases and speed-accuracy trade-off settings. In this chapter we examine the application of the diffusion model in a variety of different settings. We discuss the optimality of the model and review its applications to a number of cognitive tasks, including perception,memory, and language tasks. We also consider its applications to normal and special populations, to the cognitive foundations of individual differences, to value-based decisions, and its role in understanding the neural basis of decision-making.
Chronic Subdural Hematoma in Patients Over 90 Years Old in a Super-Aged Society

Background Chronic subdural hematoma (CSDH) is one of the most common diseases in neurosurgical practice, particularly among aged patients. With the continuing increase in the aged population, further increases in incidence are expected. However, few studies have focused on CSDH in super-aged patients over 90 years old. Methods We retrospectively reviewed medical records for 20 consecutive patients over 90 years old with CSDH treated in our department between 2007 and 2013. The diagnosis of CSDH was confirmed by computed tomography (CT). Patients were divided into a surgery group and a conservative group. Surgical procedures included burr-hole surgery followed by insertion of a subdural drain under local anesthesia. Clinical data were compared and analyzed. Neurological status was evaluated according to the modified Rankin Scale at three time points: before suffering from CSDH; at the time of referral or admission to our department; and at discharge or 1 month after the first referral. Statistical tests were used to analyze data and values of P < 0.05 were considered significant. Results Mean age for the 20 cases was 92.6 years (range, 90 - 96 years). The leading symptoms in this population were hemiparesis and gait disturbance, followed by disturbance of consciousness and speech disturbance. Twelve patients underwent burr-hole surgery. Mean maximum thickness of subdural hematoma as measured on CT was significantly higher in the surgery group (28.2 ± 5.4 mm) than in the conservative group (17.0 ± 3.8 mm; P < 0.01). Postoperatively, mean neurological status was significantly improved in the surgery group (P < 0.01). After surgery, 66.7% of patients could return home directly from hospital. No significant perioperative complications directly related to surgery were encountered in the surgery group, except for transient postoperative restlessness and bruising of extremities due to falls. Conclusions Surgery for CSDH is safe and positively recommended even in super-aged patients over 90 years old if the patient’s physical status is fair. Pre-illness status is the most important factor for considering operative indications and represents a limiting factor for postoperative outcomes in this age population.
Polyethylene glycol versus dual sugar assay for gastrointestinal permeability analysis: is it time to choose?

Background Increased intestinal permeability is an important measure of disease activity and prognosis. Currently, many permeability tests are available and no consensus has been reached as to which test is most suitable. The aim of this study was to compare urinary probe excretion and accuracy of a polyethylene glycol (PEG) assay and dual sugar assay in a double-blinded crossover study to evaluate probe excretion and the accuracy of both tests. Methods Gastrointestinal permeability was measured in nine volunteers using PEG 400, PEG 1500, and PEG 3350 or lactulose-rhamnose. On 4 separate days, permeability was analyzed after oral intake of placebo or indomethacin, a drug known to increase intestinal permeability. Plasma intestinal fatty acid binding protein and calprotectin levels were determined to verify compromised intestinal integrity after indomethacin consumption. Urinary samples were collected at baseline, hourly up to 5 hours after probe intake, and between 5 and 24 hours. Urinary excretion of PEG and sugars was determined using high-pressure liquid chromatography-evaporative light scattering detection and liquid chromatography-mass spectrometry, respectively. Results Intake of indomethacin increased plasma intestinal fatty acid-binding protein and calprotectin levels, reflecting loss of intestinal integrity and inflammation. In this state of indomethacin-induced gastrointestinal compromise, urinary excretion of the three PEG probes and lactulose increased compared with placebo. Urinary PEG 400 excretion, the PEG 3350/PEG 400 ratio, and the lactulose/rhamnose ratio could accurately detect indomethacin-induced increases in gastrointestinal permeability, especially within 2 hours of probe intake. Conclusion Hourly urinary excretion and diagnostic accuracy of PEG and sugar probes show high concordance for detection of indomethacin-induced increases in gastrointestinal permeability. This comparative study improves our knowledge of permeability analysis in man by providing a clear overview of both tests and demonstrates equivalent performance in the current setting.
Analysis of accuracy in the writing of EFL students enrolled on CLIL and non-CLIL programmes: the impact of grade and gender

ABSTRACT This paper examines written language accuracy in a content and language integrated learning (CLIL) and a non-CLIL instruction context including grade and gender in the analysis. Essays written by 393 third and fourth year CLIL and non-CLIL secondary education students were evaluated by two measures of second language (L2) accuracy: error-free sentence ratio and errors per word ratio. Errors were analysed and scored as syntactic, morphological, lexical, lexicogrammatical, spelling and punctuation errors. Results revealed that accuracy progressed with grade significantly in the CLIL instruction context whereas in the non-CLIL group only lexicogrammatical errors decreased significantly. The analysis of error subtypes revealed some cases of regression and stabilisation tendencies, with articles posing problems in both contexts and prepositions, determiners, voice, subordination and word order in the non-CLIL context. As regards gender, female participants did not significantly outperform their male peers in written accuracy in the CLIL group as they did in the non-CLIL group indicating that CLIL may help balance gender differences.
Cultural entrepreneurship: from making culture to cultural making

We summarize three perspectives on cultural entrepreneurship (CE). Originating in sociology, CE 1.0 focuses on making culture, or the processes by which high culture organizations and popular culture products are created. With roots in strategic management and organization theory, CE 2.0 focuses on deploying culture, or the processes by which culture constitutes a toolkit for legitimating new ventures. We interpret recent scholarship as suggesting the emergence of a third wave, CE 3.0, which emphasizes cultural making, the distributed and intertemporal processes whereby value is created across multiple and fluid repertoires and registers of meaning. We close by speculating on two issues: the performativity of cultural entrepreneurship, and the cult of entrepreneurship.
Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats

Abstract Background. Alpha 2 (α2)-adrenoceptor agonists may be useful for their potential to increase or prolong opioid analgesia while attenuating the development of opioid tolerance. The purpose of this study was to investigate the effects of dexmedetomidine and guanfacine (α2-adrenoceptor agonists) on morphine analgesia and tolerance in rats. Methods. Adult male Wistar albino rats weighing 195–205 g were used. To constitute morphine tolerance, animals received morphine (50 mg/kg) once daily for 3 days. After the last dose of morphine had been injected on day 4, morphine tolerance was evaluated by analgesia tests. The analgesic effects of dexmedetomidine (20 μg/kg), guanfacine (0.5 mg/kg), MK-467 (0.25 mg/kg), and morphine were estimated at 30-min intervals (0, 30, 60, 90, and 120 min) by tail-flick and hot-plate analgesia tests. Results. Our findings indicate that dexmedetomidine and guanfacine attenuated the expression of morphine tolerance. In addition, administration of dexmedetomidine with morphine increased morphine analgesia. On the contrary, data suggested that MK-467 (an α2-adrenoceptor antagonist) decreased morphine analgesia and increased morphine tolerance in analgesia tests. Conclusion. In conclusion, we observed that co-injection of dexmedetomidine or guanfacine with morphine attenuated the expression of tolerance to the analgesic effect of morphine and that dexmedetomidine enhanced the morphine analgesia.
The trajectory of life satisfaction and its associated factors among adolescents in South Korea

Abstract Korean adolescents are reportedly unhappy, dissatisfied with their lives, yet little is known about why. This study is set out to examine their life satisfaction and its change over time and the factors associated with its change. The analyses were conducted using the data from the Korean Youth Panel Survey (2004–2008) on a total of 3449 adolescents. The latent growth curve modelling result shows that Korean adolescents’ life satisfaction had a linear trajectory over a five-year period, and that while peer and teacher relationships were identified as important protective factors, academic stress and their internalised problems such as depression had long-lasting effect over time. Based on such findings, implications for social work practice with adolescents are discussed.
Audiologist-Driven Versus Patient-Driven Fine Tuning of Hearing Instruments

Two methods of fine tuning the initial settings of hearing aids were compared: An audiologist-driven approach––using real ear measurements and a patient-driven fine-tuning approach––using feedback from real-life situations. The patient-driven fine tuning was conducted by employing the Amplifit® II system using audiovideo clips. The audiologist-driven fine tuning was based on the NAL-NL1 prescription rule. Both settings were compared using the same hearing aids in two 6-week trial periods following a randomized blinded cross-over design. After each trial period, the settings were evaluated by insertion-gain measurements. Performance was evaluated by speech tests in quiet, in noise, and in time-reversed speech, presented at 0° and with spatially separated sound sources. Subjective results were evaluated using extensive questionnaires and audiovisual video clips. A total of 73 participants were included. On average, higher gain values were found for the audiologist-driven settings than for the patient-driven settings, especially at 1000 and 2000 Hz. Better objective performance was obtained for the audiologist-driven settings for speech perception in quiet and in time-reversed speech. This was supported by better scores on a number of subjective judgments and in the subjective ratings of video clips. The perception of loud sounds scored higher than when patient-driven, but the overall preference was in favor of the audiologist-driven settings for 67% of the participants.
Resonant co-creation as an approach to strategic innovation

Purpose The purpose of this paper is to conceptualize resonant co-creation as a framework for cultivating strategic innovation and organizational change; to delineate worldview transformation as central to resonant co-creation and overview the theoretical and practical foundations of this approach; and to offer a model on the facilitation of resonant co-creation in organizations. Design/methodology/approach Conceptual development with case illustration. Findings Resonant co-creation fosters strategic innovation through coaching and facilitation techniques that cultivate awareness, empathy, and advanced communication skills. This results in a fundamental shift in the engagement and interactions of teams, creating a new space for innovation. Research limitations/implications The framework offered herein brings conceptual clarity to specific approaches to and applications of resonant co-creation to achieve strategic innovation. By providing perspective on processes leading to innovation, it possible to be more precise about the relationships between consulting practices and stated organizational change outcomes. Practical implications The presentation and clarification of the theoretical model (the underlying grammar of facilitation) and specific techniques that can be used to drive worldview transformation can benefit coaches, facilitators, and leaders who wish to implement a co-creative organizational culture or improve outcomes of co-creative programs. By linking theory to practice, this paper can help change makers and managers better justify and implement resonant co-creation within their organizational contexts. Social implications Resonant co-creation facilitates an expansion of awareness that can lead to more sustainable business practices and workplace well-being. This benefits society at large through fostering more socially conscious and innovative organizations. Originality/value Resonant co-creation is a needed nuance to the very generalized notion of co-creation spread throughout organizations today. Clarifying this approach is useful to both practitioners and researchers who seek to understand or facilitate innovation and organizational change. The originality of this paper lies in the combination of the idea of co-creation with the psychological concept of worldview transformation. By creating shifts in individual and collective (organizational) worldview, resonant co-creation transforms the way people interact and ideate. This paper introduces a grammar of facilitation and specific techniques that shift worldview and create a space for strategic innovation.
The influence of mood on tunnel vision in crime investigation : can mood decide whether we hold on to our initial beliefs?

Over the past two decades there has been more and more attention for the influence of affect on decision making (Slovic et al., 2002). When comparing individuals in a happy mood to those in a sad mood, results of various studies show that happiness leads to less cognitive effort and more reliance on heuristics. In contrast, sadness promotes the gathering and systematic analyzing of all evidence and information, which costs more effort (Bodenhausen et al., 1994; Findley, 2006; Lerner & Keltner, 2000). In the present study it is investigated whether a sad mood increases the tendency to process information in a thoroughly and accurate manner, and thereby causes the individual to be less susceptible to contradictory information presented at a later stage. Fifty subjects, representing a sample of the general population, participated in this experimental study and were asked to generate causal scenarios for the disappearance of a young women. Consecutively, they received a realistic prior interpretation constructed by an investigation team, indicating that the father was involved in the woman’s disappearance. Although the presented contradictory information does not provide sufficient proof of the father’s guilt, it was adequate enough to make him suspicious. A 1-factor between subjects design with two levels (sadness versus happiness) was used in this study. The results show that sad participants who initially thought the young women ran away from home, were less willing to alter their initial beliefs than happy participants. However, the most probable scenario was indeed that the woman voluntarily has left her parents’ home. While the interpretation of the police team makes the father suspicious, it does not provide substantial evidence for his guilt. We conclude that sad participants hold on to their initial beliefs, but only when they are correct.
Identifying Factors of E-Government Acceptance - A Literature Review

The digital revolution has arrived in the halls of public administrations. E-Government, which has been a buzzword for all kinds of computer usage in the governmental context for several years, has started to become an ordinary way for public administrations to organise their work. Document and workflow management systems as well as process reorganisation in the backend and electronic taxation systems or digital ID cards on the frontend side all belong to the portfolio of concepts summarised by e-Government. However, in spite of the advantages that go along with these developments, adoption of e-Government services is still rather low both on the citizens’ side as well as by the employees of public administrations. We conducted a literature review identifying the factors that influence the acceptance of e-Government services by different stakeholders and provide a framework of future research needs.