Miracle-dz/UniFAR-FTUs huggingface dataset:
Commitment in Structurally Enabled and Induced Exchange Relations

Network structures both enable and constrain the development of social relations. This research investigates these features by comparing the development of commitments in structurally enabled and structurally induced exchange relations. We integrate ideas from the theory of relational cohesion and the choice process theory of commitment. In an experiment we manipulate and compare a structurally enabled relation with a structurally induced relation. The main hypotheses are that a structurally enabled relation generates a greater sense of control, more positive emotions, greater perceived cohesion, and more commitment behavior than a structurally induced relation. The results of the experiment support these hypotheses. The implication is that enabling and constraining features of network structures exert important effects on cohesion and commitment in relations within those structures.
What Were the Tweets About? Topical Associations between Public Events and Twitter Feeds

Social media channels such as Twitter have emerged as platforms for crowds to respond to public and televised events such as speeches and debates. However, the very large volume of responses presents challenges for attempts to extract sense from them. In this work, we present an analytical method based on joint statistical modeling of topical influences from the events and associated Twitter feeds. The model enables the auto-segmentation of the events and the characterization of tweets into two categories: (1) episodic tweets that respond specifically to the content in the segmentsof the events, and (2) steady tweets that respond generally about the events. By applying our method to two large sets of tweets in response to President Obama's speech on the Middle East in May 2011 and a Republican Primary debate in September 2011, we present what these tweets were about. We also reveal the nature and magnitude of the influences of the event on the tweets over its timeline. In a user study, we further show that users find the topics and the episodic tweets discovered by our method to be of higher quality and more interesting as compared to the state-of-the-art, with improvements in the range of 18-41%.
A Causal Analysis of the Defense Expenditures of the USA and the USSR

Statistical studies of the determinants of defense expenditures have been criticized on two counts: (a) most of them do not test the hypotheses of causality that they include, but simply use them as a point of departure, and (b) those that do test causality are restricted to conceptual models with very few explanatory variables. The objective of this paper is to study the defense expenditures of the USA and the USSR, explicitly avoiding these two limitations. This is done using elementary statistical methods in somewhat unorthodox ways. The conclusions of the analyses are carefully compared with those obtained by other authors and the differences encountered are explained as far as possible. The analyses and comparisons show that the defense expenditures of the USA are determined by their own inertia and by political factors within the country, while those of the USSR are determined by their own inertia and the conditions of relations with the USA. The interest of these results is not in their novelty, but in the fact that they are obtained with procedures designed to provide a more solid foundation.
Effects of Repeated Administration of Pilocarpine and Isoproterenol on Aquaporin-5 Expression in Rat Salivary Glands

Aquaporins are water channel proteins which enable rapid water movement across the plasma membrane. Aquaporin-5 (AQP5) is the major aquaporin and is expressed on the apical membrane of salivary gland acinar cells. We examined the effects of repeated administration of pilocarpine, a clinically useful stimulant for salivary fluid secretion, and isoproterenol (IPR), a stimulant for salivary protein secretion, on the abundance of AQP5 protein in rat salivary glands by immunofluorescence microscopy and semi-quantitative immunoblotting. Unexpectedly AQP5 was decreased in pilocarpine-administered salivary glands, in which fluid secretion must be highly stimulated, implying that AQP5 might not be required for fluid secretion at least in pilocarpine-administered state. The abundance of AQP5, on the other hand, was found to be significantly increased in IPR-administered submandibular and parotid glands. To address the possible mechanism of the elevation of AQP5 abundance in IPR-administered animals, changes of AQP5 level in fasting animals, in which the exocytotic events are reduced, were examined. AQP5 was found to be decreased in fasting animals as expected. These results suggested that the elevation of cAMP and/or frequent exocytotic events could increase AQP5 protein. AQP5 expression seems to be easily changed by salivary stimulants, although these changes do not always reflect the ability in salivary fluid secretion.
STAR: Steiner-Tree Approximation in Relationship Graphs

Large graphs and networks are abundant in modern information systems: entity-relationship graphs over relational data or Web-extracted entities, biological networks, social online communities, knowledge bases, and many more. Often such data comes with expressive node and edge labels that allow an interpretation as a semantic graph, and edge weights that reflect the strengths of semantic relations between entities. Finding close relationships between a given set of two, three, or more entities is an important building block for many search, ranking, and analysis tasks. From an algorithmic point of view, this translates into computing the best Steiner trees between the given nodes, a classical NP-hard problem. In this paper, we present a new approximation algorithm, coined STAR, for relationship queries over large relationship graphs. We prove that for n query entities, STAR yields an O(log(n))-approximation of the optimal Steiner tree in pseudopolynomial run-time, and show that in practical cases the results returned by STAR are qualitatively comparable to or even better than the results returned by a classical 2-approximation algorithm. We then describe an extension to our algorithm to return the top-k Steiner trees. Finally, we evaluate our algorithm over both main-memory as well as completely diskresident graphs containing millions of nodes. Our experiments show that in terms of efficiency STAR outperforms the best state-of-the-art database methods by a large margin, and also returns qualitatively better results.
Lip carcinoma: clinical presentation, surgical treatment, and outcome: a series of 108 cases from Denmark

Abstract Objective: Lip carcinomas are among the most common malignant tumours of the head and neck region but reports on the course and outcome of this disease are mainly based on Mediterranean, South American, and Oceanian populations. The aim of the study was to describe the treatment and outcome of patients with lip carcinoma at a Danish department of plastic surgery. Method: We conducted a single institution retrospective cohort study including patients with primary cancer of the lips including squamous cell (SCC), basal cell (BCC), and basosquamous carcinomas (BSC) in a 5-year period. Results: We included 108 consecutive patients. Median age was 72 years (range 28 -98) and 58% were male. Seventy patients (65%) were diagnosed with SCC, 36 (33%) BCC, and 2 (2%) BSC. The majority of lesions were stage T1 (84%) and T2 (11%). An unexpected total of 35 (32%) patients experienced wound healing problems; whereof 19 (54%) classified as mild (not demanding treatment), 10 (29%) as moderate (non-functional surgical corrections or medical treatment of infection needed) and 6 (17%) experienced severe dehiscence (requiring surgical intervention for functional improvement). Total defect size ≥20 mm and full thickness excision was directly correlated to the risk of early postoperative complications (p-value: 0.03 and 0.04). Three patients (2/36 with BCC; 6% and 1/70 with SCC; 1%) developed local recurrence and five patients with SCC (5/70; 7%) developed regional lymph node metastases. One patient (1%) died from metastatic SCC. Conclusion: This study confirms that lip carcinoma is associated with a risk of recurrence and mortality. However, the risk of wound complications is notable compared to other series.
An Analysis of Penalty Kicks in Elite Football Post 1997

The penalty kick in football is a seemingly simplistic play; however, it has increased in complexity since 1997 when the rules changed allowing goalkeepers to move laterally along their goal line before the ball was kicked. Prior to 1997 goalkeepers were required to remain still until the ball was struck. The objective of this study was to determine the importance of the penalty kick in the modern game of football. A retrospective study of the 2002, 2006 and 2010 World Cup and the 2000, 2004 and 2008 European Championship tournaments was carried out, assessing the importance of the penalty kick in match play and shootouts and the effect of the time of the game on the shooter's success rate. This study demonstrated the conversion rate of penalties was 73% in shootouts and 68% in match play. Significantly more penalties were awarded late in the game: twice as many penalties in the second half than the first and close to four times as many in the fourth quarter vs. the first. Teams awarded penalty kicks during match play won 52%, drew 30% and lost 18% of the time; chances of winning increased to 61% if the penalty was scored, but decreased to 29% if missed. Teams participating in either the World Cup or European Championship final match had roughly a 50% chance of being involved in a penalty shootout during the tournament. Penalty shots and their outcome significantly impact match results in post 1997 football.
Stability and Change in Belief Systems

Cognitive frameworks and belief systems are the primary lenses through which presidents view the world. Two important questions are whether these beliefs ever change significantly, and if so, what causes these changes? This article develops empirical data on the strategic and operational beliefs of President George W. Bush (GWB) as a means of examining the theoretical basis for how and why core beliefs change. The author analyzes the foreign policy operational code of President Bush in four separate phases of his political career: the immediate prepresidential phase; his nine months in office prior to September 11, 2001; the six months immediately following the 9/11 terrorist attacks; and his last year in office as a second-term president. The results of this article allow us to address several recurring questions that concern the Bush administration and presidents' belief systems and decision making. They challenge traditional interpretations of the Bush presidency and provide some insights into the causal mechanisms that underlie belief change.
Convention, Form, and Figurative Language Processing

There are 2 basic controversies concerning how metaphors are processed. First, are metaphoric mappings more akin to literal comparisons or to literal categorizations? And second, is metaphor comprehension indirect or direct? We believe that these controversies are more apparent than real and that a unified theoretical framework can be offered that reconciles these opposing views. The central idea is that all metaphors involve structural alignment of the target and base domains. Whether these alignments are more akin to comparisons or to categorizations, and whether they are computed directly or indirectly, depends on 2 factors: the type of representation invoked by the base term and the linguistic form of the metaphor.
Improving students' argumentation skills through a product life-cycle analysis project in chemistry education

The aim of the study discussed in this paper was to link existing research about the argumentation skills of students to the teaching of life-cycle analysis (LCA) in order to promote an evidence-based approach to the teaching of and learning about materials used in consumer products. This case-study is part of a larger design research project that focuses on improving education for sustainable development (ESD) in chemistry teaching by means of combining a socio-scientific issue (SSI) and life-cycle analysis with inquiry-based learning. The research question was: How do students (N = 8) use scientific, ecological, socio-economical and ethical argumentation in the life-cycle analysis of a product? The research method for this study was content analysis performed on written student answers and an audio recording of a debate. The results show that the students' scientific and ecological argumentation skills with regard to the life-cycles of products were improved during the life-cycle analysis project. The studying also affected, to a lesser extent, the students' ability to form socio-economical and ethical arguments. The type of student-centred and cross-curricular product life-cycle analysis project discussed in this paper is a suitable new method for teaching socio-scientific argumentation to chemistry students at the secondary school level.
Cytochrome c Release upon Fas Receptor Activation Depends on Translocation of Full-length Bid and the Induction of the Mitochondrial Permeability Transition*

In Jurkat cells Bid was cleaved upon activation of the Fas receptor with an anti-Fas antibody. The caspase-8 inhibitor benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F (IETD) prevented the cleavage of Bid and the loss of viability. The nuclear enzyme poly(ADP-ribose)polymerase (PARP) was also cleaved upon the activation of caspases, and IETD similarly prevented PARP cleavage. The PARP inhibitor 3-aminobenzamide (3-AB) restored the cell killing in the presence of IETD, an effect that occurred without restoration of the cleavage of Bid or PARP. In the presence of 3-AB and IETD, translocation occurred of full-length Bid to the mitochondria. The induction of the mitochondrial permeability transition (MPT) was documented by the cyclosporin A (CyA) sensitivity of the release of cytochrome c, the release of malate dehydrogenase from the mitochondrial matrix, the loss of the mitochondrial membrane potential, and the pronounced swelling of these organelles, as assessed by electron microscopy. In addition to preventing all evidence of the MPT, CyA prevented the loss of cell viability, without effect on the cleavage of either Bid or PARP. The prevention of PARP cleavage by inhibition of caspase-3 resulted in a 10-fold activation of the enzyme and a resultant depletion of NAD and ATP. The PARP inhibitor 3-AB prevented the loss of NAD and ATP. Depletion of ATP by metabolic inhibitors similarly prevented the cell killing. It is concluded that the cleaving of PARP in Fas-mediated apoptosis allowed expression of an energy-dependent cell death program that included the translocation of full-length Bid to the mitochondria with induction of the MPT.
Assessment of bibliographic databases performance in information retrieval for occupational and environmental toxicology.

OBJECTIVE: To determine the efficiency of the major bibliographic databases by assessing the percentage of references among the total literature available that can be retrieved from each database. We also evaluated the best database combinations to carry out an exhaustive search. METHODS: BIOSIS, EMBASE, MEDLINE, NIOSH-TIC, and TOXLINE were searched on two topics: allergy to latex and asbestos and mesothelioma, in the title, abstract, or keywords (textwords). This search was performed for the years 1994 and 1995. All the records were classified by journal and author's name and were verified for each record whether or not it was indexed in each database. Statistical analysis was performed with chi 2 test. RESULTS: 777 articles in 510 issues were found. The efficiency of each database (percentage of articles recovered) and of combinations varied between 11% and 63% for one database and between 42% and 86% for a combination of two databases. The reasons why these differences exist between databases, and within a database, between two different subjects or two different years are reported. CONCLUSION: Firstly, it is not advisable to assert that a bibliography is complete when only one database is searched. Secondly, the efficiency of the databases may be quite different. Finally, it is suggested that the best way to be as exhaustive as possible is to search two or more databases-for example, in EMBASE and TOXLINE, or to a lesser extent EMBASE and MEDLINE. This seems to be the best compromise solution between time consumed for searching and efficiency.
Making objective facts from intimate relations: the case of neuroscience and its entanglements with volunteers

This article explores the way in which the practice of neuroscience, in the form of contemporary brain-imaging, has to actively define and isolate aspects of mindfulness as solely contained within the individual. Although hidden from final scientific accounts, at the centre of this process is the need for the researchers to forge brief but intimate and personal relationships with the volunteers in their studies. With their increasing interest in studying more and more complex mental processes, and in particular as researchers focus on what they term `the social brain', a potential paradox arises from the commitment to the straightforward location of brain function and recognition of the more distributed and intersubjective nature of the objects of their study. Consequently, in order to elicit specific mental activities, such as empathy, the scientists inevitably employ a range of socially based resources, which includes establishing a personal relationship with the volunteers. The scientists themselves see this as ensuring that they can trust that the volunteers will participate in the ways intended. But in contrast, the article argues that the central feature is actually the creation of a sense of intimacy, which serves to align the expectations and experiences of volunteer and researcher. Yet, while this relationship is necessary in order to ensure the required mental state is generated, during the experiment itself a great deal of work is then done to ensure it can be excluded from the final conceptualization of mental activity.
Reassessment of Id 1 Protein Expression in Human Mammary , Prostate , and Bladder Cancers Using a Monospecific Rabbit Monoclonal Anti-Id 1 Antibody

Id proteins are a class of dominant-negative antagonists of helix-loop-helix transcription factors and have been shown to control differentiation of a variety of cell types in diverse organisms. Although the importance of Id1 in tumor endothelial cells is well established, the expression and role of the Id1 protein in human cancer cells is controversial. To explore this issue, we developed and characterized a highly specific rabbit monoclonal antibody against Id1 to assess its expression in human breast, prostate, and bladder malignancies. Our results show that in usual types of human mammary carcinomas, the Id1 protein is expressed exclusively in the endothelium. Interestingly, we detected nuclear expression of the Id1 protein in the tumor cells in 10 of 45 cases of poorly differentiated and highly aggressive carcinoma with metaplastic morphology. Similarly, only 1 of 30 prostate cancer samples showed Id1-positive tumor cells, whereas in almost all, endothelial cells showed high Id1 expression. Intriguingly, whereas normal prostate glands do not show any Id1 protein expression, basal layer cells of benign prostate glands in proximity to tumors expressed high levels of the Id1 protein. In contrast to the lack of Id1 expression in the usual types of mammary and prostate cancers, the majority of transitional cell bladder tumors showed Id1 protein expression in both tumor and endothelial cells. These results suggest that further refinement of Id1 expression patterns in a variety of tumor types will be necessary to identify and study the functional roles played by Id1 in human neoplastic processes. (Cancer Res 2006; 66(22): 10870-7)
Standards for medical devices in MRI: Present and future

The purpose of this review is to define the current standards addressing safety of medical devices in MRI and to describe ongoing standards development efforts. The American Society for Testing and Materials (ASTM International) began developing standard test methods for determining the MR safety of medical devices in MRI in 1997. To date, five ASTM standards addressing testing and marking medical devices and other items for use in the MR environment have been published. International Standards Organization (ISO) 14630, the general requirements standard for nonactive surgical implants, is currently being revised to include information about MR safety of passive implants and to reference the ASTM standards. To address the unique safety issues of active implants, and in particular, active implants with leads, like pacemakers and neurostimulators, a joint working group between ISO TC150/SC6 on active implants and International Electrotechnical Commission (IEC) SC 62B MT40 on magnetic resonance equipment for medical diagnosis is working to develop a technical specification for active implantable medical devices (AIMDs) in MRI. While much progress has been made, work still needs to continue to develop a complete body of test methods to allow the evaluation of the safety of medical devices in the MR environment. J. Magn. Reson. Imaging 2007;26:1186–1189. © 2007 Wiley‐Liss, Inc.
Notes on the Construction of a 'Subjective Vitality Questionnaire' for Ethnolinguistic Groups.

Group ‘vitality’ was recently proposed as a framework for objectively categorizing ethnolinguistic groups in terms of their ability to behave as distinctive collective entities in intergroup settings (Giles, Bourhis & Taylor, 1977). ‘Objective’ accounts of group vitality using status, demographic and institutional support data gathered from secondary sources appear a useful tool for comparing ethnolinguistic groups in cross‐cultural research. This article describes a new questionnaire designed to assess how group members subjectively perceive their owngroup position relative to salient outgroups on important ‘vitality’ dimensions. Group members’ ‘subjective’ vitality perceptions may be as important in determining interethnic behaviours as the Group's objectively assessed vitality. The article includes a discussion of how ‘objective’ and ‘subjective’ vitality information can be combined to better account for the dynamics of interethnic relations in multilingual and multicultural settings.
Long-term follow-up of cochlear implant users with ossified cochlea.

OBJECTIVE Cochlear implantation surgery in ossified cochlea is a challenge, even for the experienced otologist. Short-term assessments of auditory perception show that implantation in partial or even extensive ossified cochlea could be achieved with varying success, but no long-term follow-up results have been published yet. DESIGN AND METHODS This paper proposes a retrospective review of eight Nucleus cochlear implant users with ossified cochlea who have been followed on a 12- to 60-month period. MAIN OUTCOME MEASURE Auditory performances of users are reported at each control on a scale of 100 units divided into 4 skill zones of 25 units based on Erber's proposition, that is, detection, discrimination, identification, and recognition. RESULTS Three of the eight subjects showed some progression in their auditory performances during the follow-up. The five other subjects showed no long-term progress in their auditory performance. CONCLUSIONS Open-set comprehension could be achieved with the insertion of 9 to 10 electrodes of the Nucleus device. Auditory performance in users with ossified cochlea seems to be influenced by the same factors as in users with patent cochlea.