Miracle-dz/UniFAR-FTUs huggingface dataset:
Reworking of the Gangdese magmatic arc, southeastern Tibet: post‐collisional metamorphism and anatexis

The Gangdese magmatic arc, southeastern Tibet, was built by mantle‐derived magma accretion and juvenile crustal growth during the Mesozoic to Early Cenozoic northward subduction of the Neo‐Tethyan oceanic slab beneath the Eurasian continent. The petrological and geochronological data reveal that the lower crust of the southeastern Gangdese arc experienced Oligocene reworking by metamorphism, anatexis and magmatism after the India and Asia collision. The post‐collisional metamorphic and migmatitic rocks formed at 34–26 Ma and 28–26 Ma respectively. Meta‐granitoids have protolith ages of 65–38 Ma. Inherited detrital zircon from metasedimentary rocks has highly variable ages ranging from 2708 to 37 Ma. These rocks underwent post‐collisional amphibolite facies metamorphism and coeval anatexis under P–T conditions of ~710–760 °C and ~12 kbar with geothermal gradients of 18–20 °C km−1, indicating a distinct crustal thickening process. Crustal shortening, thickening and possible subduction erosion due to the continental collision and ongoing convergence resulted in high‐P metamorphic and anatectic reworking of the magmatic and sedimentary rocks of the deep Gangdese arc. This study provides a typical example of the reworking of juvenile and ancient continental crust during active collisional orogeny.
Tyrosine, Phenylalanine, and Tryptophan in Gastroesophageal Malignancy: A Systematic Review

Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival. The aromatic amino acids tyrosine, phenylalanine, and tryptophan represent potential biomarkers and their relation to gastroesophageal cancer will be evaluated in this review. An electronic literature search was performed to identify all published research relating to the measurement of tyrosine, phenylalanine, or tryptophan in the biofluids or tissues of patients with gastroesophageal cancer. Sixteen studies were included in this systematic review. Six studies investigated serum concentrations, which all found decreased concentrations of these aromatic amino acids, except one study that found increased phenylalanine. Five studies reported increased concentrations within gastric content of these patients and two reported increased urinary concentrations. Tissue concentrations of these aromatic amino acids were increased in three studies. Tyrosine, phenylalanine, and tryptophan represent potential biomarkers of gastroesophageal cancer, and further research is necessary to definitively establish the mechanism responsible for altered concentrations of these compounds in patients with gastroesophageal cancer. Cancer Epidemiol Biomarkers Prev; 24(1); 32–38. ©2014 AACR.
Diversity and Seasonal Dynamics of an Assemblage of Sarcophagid Diptera in a Gradient of Urbanization

Abstract Sarcophagid species inhabiting different locations in a rural-urban gradient were surveyed in the east central Argentine district of the Almirante Brown, Buenos Aires province. The main objectives of this research were to identify the most prevalent sarcophagid species and to describe community richness and diversity according to the degree of urbanization and the environmental variables measured in three locations within a rural-urban gradient sampled during two years from May 2005 to April 2007. Spatial and seasonal variations were the main factors involved in structuring the sarcophagid communities. Diversity was lower in urbanized areas than in rural ones. Bait and microhabitat preferences (sunny or shady places) and seasonal fluctuations were described for 17 sarcophagid species.
A Comparison of Hawai'i and National Home-Based Family Businesses

F businesses are an integral sector of the American economy. They constitute approximately 90% of all U.S. firms and are estimated to account for half of the country’s gross national product (Bowman-Upton 1991). They are also spread over a large number of households: by 1998, Heck and Stafford (1999) estimated that 13.8% of all American families had at least one family business operating from the home. In addition, family businesses vary greatly in size and revenue, from traditional singlehousehold small businesses to approximately a third of the Fortune 500 firms (Riordan and Riordan 1993). The growth of family businesses has been matched by an increase in home-based employment over the past two decades. According to data from the 2000 U.S. Census, 2.3% of American workers worked from home in 1980; the figure rose to 3.0% in 1990 and to 3.3% in 2000. In addition to the overall growth of home-based employment, home-based workers are engaging in an increasing range of industries, with technology-based white-collar jobs gaining greater prominence (Heck and Stafford 1999). In terms of family businesses, the 1997 National Family Business Survey (NFBS) showed 57.7% to be home-based. Despite the increase in the number of family and homebased businesses, there is limited research on home-based family businesses, especially in Hawai‘i. To increase understanding of this subset of small businesses, this study was designed to (1) examine the state of home-based family businesses in Hawai‘i, and (2) compare homebased family businesses inHawai‘i with those in the entire United States. Attention will be focused on construction and services industries because they aremajor contributors to tax revenues in the state (Bureau of EconomicAnalysis 2002, 2007), and also on agriculture because of growing public concern about food safety and healthy diets (Hawaii Farm Bureau Federation 2004, p. 9).
Seasonal and interannual variability of atmospheric convergence zones in the tropical Pacific observed with ERS‐1 scatterometer

Monthly images of atmospheric convergence zones in the tropical Pacific were produced with 1992–1994 ERS‐1 scatterometer wind vectors. From the images, the position, width, and intensity of the convergence zones can be determined. Latitude‐time sections of ocean surface wind divergence show that the summer position of the ITCZ in the eastern Pacific during the observed period exceeded the normal position northward by 3°–6° latitude, and the annual cycle in the western Pacific for 1994 was quite weak, implying a persistently unusual case.
Offshoring and Cross-Border Interorganizational Relationships: A Justice Model

In this article, we develop an interorganizational justice model to explain cross-border interorganizational relationships. The model contends that cultural distance (construed as the cultural differences between offshoring partners) would influence behavioral uncertainty and the boundary spanners' perceptions of justice. Specifically, the model predicts that high levels of behavioral uncertainty are likely to reduce relational commitment, whereas low levels of behavioral uncertainty are likely to enhance relational commitment. However, boundary spanners' perceptions of distributive, procedural, and interactional justice would mitigate the negative impact of behavioral uncertainty on relational commitment. The model also predicts that culturally similar boundary spanners would be more likely to share similar perceptions of distributive, procedural, and interactional justice than culturally dissimilar boundary spanners. This model has implications for further theoretical discussion and empirical research as well as management practice. Managers could use the interorganizational justice model to assess shared perceptions of justice among boundary spanners and develop transcultural justice competencies.
New frame rate up-conversion using bi-directional motion estimation

We propose a new frame rate up-conversion algorithm for high quality video. In the proposed scheme, bi-directional motion estimation (ME) is performed to construct the motion vector (MV) field for the frame to be interpolated. Unlike conventional motion-compensated interpolation (MCI) algorithms, the proposed technique does not produce any overlapped pixel and hole region in the interpolated frame, and thus can utilize the overlapped block motion compensation technique to reduce the blocking artifacts. The proposed algorithm is very simple to implement on consumer products when compared to conventional MCI methods. Computer simulation shows a high visual performance of the proposed frame rate up-conversion algorithm.
Prospective evaluation of magnetic resonance imaging after endovascular treatment of infrarenal aortic aneurysms.

OBJECTIVES to evaluate the sensitivity and specificity of magnetic resonance imaging (MRI) in the detection of type II endoleaks during follow-up after endovascular treatment of intra-renal aortic aneurysms. DESIGN prospective study. MATERIAL AND METHODS between March 1996 and November 1999, 31 patients with infra-renal aortic aneurysms who underwent stentgraft implantation were followed with helical CT and MRI, including magnetic resonance angiography (MRA), at 1 and 6 months after the procedure. Arteriography was performed between 6 and 12 months after intervention. The parameters studied included the change in the maximum anteroposterior and transverse diameters, the nature of the signal on T1 and T2 weighted sequences (homogeneous vs heterogeneous), the presence or absence of Gadolinium uptake on MRI or of contrast uptake on helical CT (early and late phases) in the sac of the aneurysm. On MRA, stentgraft patency and endoleak detection were studied. RESULTS arteriography demonstrated an endoleak in 19 patients (18 type II, and 1 type I endoleak). MRI at 6 months detected 18/19 endoleaks on T1 weighted sequences after injection of Gadoliniumj; there were 2 false positives. MRA sequences confirmed stentgraft patency in all patients, but did not diagnose type II endoleaks. Helical CT (late phase) at 6 months detected 10/19 endoleaks; there was 1 false positive. The sensitivity of MRI after injection of Gadolinium and of helical CT for the detection of type II endoleaks were 94% and 50% (p=0.003) respectively. The mean maximal anteroposterior and transverse diameters were similar on MRI and on helical CT at 1 month and at 6 months. CONCLUSION MRI after injection of Gadolinium is more sensitive than helical CT in the detection of type II endoleaks after stentgraft implantation. Its more widespread use may permit earlier intervention in such patients.
Effects of road transportation on metabolic and immunological responses in Holstein heifers.

This study examined the effects of road transportation on metabolic and immunological responses in dairy heifers. Twenty Holstein heifers in early pregnancy were divided into non-transported (NT; n = 7) and transported (T; n = 13) groups. Blood was collected before transportation (BT), immediately after transportation for 100 km (T1) and 200 km (T2), and 24 h after transportation (AT). The T heifers had higher (P < 0.05) blood cortisol and non-esterified fatty acid concentrations after T1 and T2 than did NT heifers. By contrast, the T heifers had lower (P < 0.05) serum triglyceride concentrations after T1 and T2 than had the NT heifers. The serum cortisol and triglyceride concentrations returned (P > 0.05) to the BT concentrations at 24 h AT in the T heifers. The granulocyte-to-lymphocyte ratio and the percentage of monocytes were higher (P < 0.05) after T2 in the T heifers than in the NT heifers, suggesting that transportation stress increased the numbers of innate immune cells. T heifers had higher (P < 0.01) plasma haptoglobin concentrations than NT heifers 24 h AT. In conclusion, transportation increased cortisol secretion and was correlated with increased metabolic responses and up-regulation of peripheral innate immune cells in dairy heifers.
Soil respiration in response to year‐to‐year variations in rainfall in a tropical seasonal forest in northern Thailand

In a tropical deciduous forest in northern Thailand, an area affected by the Asian monsoon, we made soil respiration measurements for 4 years to determine their inter‐annual variability. We also made continuous measurements of soil moisture, soil temperature, and soil CO2 concentration. Annual soil respiration rates were estimated using two methods: multiple regression analysis and Fick's first law of diffusion. During the study period, between June 2000 and December 2004, the annual rainfall and the length of the wet period showed considerable year‐to‐year variation, differing by 1162–1435 mm year−1 falling over 146–189 days, respectively. In response to the inter‐annual variability in rainfall, annual soil respiration rates estimated by the two models also showed large inter‐annual variations for the 4 years (coefficient of variation = 14–17%). The range in the inter‐annual variation for soil respiration was comparable with values for net ecosystem exchange reported in other Southeast Asian tropical forests. Historical rainfall records at this site showed further large inter‐annual variations that occurred in times other than in the study period, suggesting that long‐term monitoring would be required for a better understanding of the C balance at this site. Copyright © 2012 John Wiley & Sons, Ltd.
Simulating the effects of short-term synaptic plasticity on postsynaptic dynamics in the globus pallidus

The rat globus pallidus (GP) is one of the nuclei of the basal ganglia and plays an important role in a variety of motor and cognitive processes. In vivo studies have shown that repetitive stimulation evokes complex modulations of GP activity. In vitro and computational studies have suggested that short-term synaptic plasticity (STP) could be one of the underlying mechanisms. The current study used simplified single compartment modeling to explore the possible effect of STP on the activity of GP neurons during low and high frequency stimulation (HFS). To do this we constructed a model of a GP neuron connected to a small network of neurons from the three major input sources to GP neurons: striatum (Str), subthalamic nucleus (STN) and GP collaterals. All synapses were implemented with a kinetic model of STP. The in vitro recordings of responses to low frequency repetitive stimulation were highly reconstructed, including rate changes and locking to the stimulus. Mainly involved were fast forms of plasticity which have been found at these synapses. The simulations were qualitatively compared to a data set previously recorded in vitro in our lab. Reconstructions of experimental responses to HFS required adding slower forms of plasticity to the STN and GP collateral synapses, as well as adding metabotropic receptors to the STN-GP synapses. These finding suggest the existence of as yet unreported slower short-term dynamics in the GP. The computational model made additional predictions about GP activity during low and HFS that may further our understanding of the mechanisms underlying repetative stimulation of the GP.
Synsedimentary tensional features in Upper Triassic shallow‐water platform carbonates of the Carnian Prealps (northern Italy) and their importance as palaeostress indicators

The extensive shallow‐water carbonate platform deposits of the Dolomia Principale Formation (Southern Alps, northern Italy) accumulated during the Late Triassic, a time of plate‐scale reorganization and rifting. Synsedimentary tensional features such as fractures, neptunian dykes, normal faults, shatter breccias and laterally discordant intraformational breccias have been studied within a well‐preserved platform‐to‐basin transition in the Monte Pramaggiore area (Carnian Prealps). These tensional features follow three preferential orientations: N–S, E–W and NE–SW. To fully explain these different arrays it is proposed that the study area experienced during the Late Triassic the waning rifting phase connected to the westward propagation of the NeoTethys (N–S extension) and the onset of the rifting phase that led in the Middle Jurassic to the opening of the Central Atlantic (E–W extension), with a contemporaneous reactivation of Early–Middle Triassic NE–SW‐orientated faults. This palaeostress analysis reveals the good potential of tensional features as reliable palaeostress indicators.
Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity

Significance Muscle glycogen fuels exercising muscles to sustain endurance capacity. The brain also stores glycogen in astrocytes to produce lactate as an energy source transported to active neurons via the monocarboxylate transporter MCT2. Although physical exercise activates brain neurons and increases their energy demand, the energetic role of astrocytic glycogen in the exercising brain remains unknown. To address this issue, we used a rat model of prolonged exhaustive exercise, microwave irradiation of brains, metabolomics, and intracerebroventricular injection of inhibitors of glycogenolysis and MCT2. Our findings provide direct evidence that lactate derived from astrocytic glycogen fuels the prolonged-exercising brain to maintain endurance capacity. This new perspective on brain energetics during endurance exercise could lead to better strategies for endurance performance. Brain glycogen stored in astrocytes provides lactate as an energy source to neurons through monocarboxylate transporters (MCTs) to maintain neuronal functions such as hippocampus-regulated memory formation. Although prolonged exhaustive exercise decreases brain glycogen, the role of this decrease and lactate transport in the exercising brain remains less clear. Because muscle glycogen fuels exercising muscles, we hypothesized that astrocytic glycogen plays an energetic role in the prolonged-exercising brain to maintain endurance capacity through lactate transport. To test this hypothesis, we used a rat model of exhaustive exercise and capillary electrophoresis-mass spectrometry–based metabolomics to observe comprehensive energetics of the brain (cortex and hippocampus) and muscle (plantaris). At exhaustion, muscle glycogen was depleted but brain glycogen was only decreased. The levels of MCT2, which takes up lactate in neurons, increased in the brain, as did muscle MCTs. Metabolomics revealed that brain, but not muscle, ATP was maintained with lactate and other glycogenolytic/glycolytic sources. Intracerebroventricular injection of the glycogen phosphorylase inhibitor 1,4-dideoxy-1,4-imino-d-arabinitol did not affect peripheral glycemic conditions but suppressed brain lactate production and decreased hippocampal ATP levels at exhaustion. An MCT2 inhibitor, α-cyano-4-hydroxy-cinnamate, triggered a similar response that resulted in lower endurance capacity. These findings provide direct evidence for the energetic role of astrocytic glycogen-derived lactate in the exhaustive-exercising brain, implicating the significance of brain glycogen level in endurance capacity. Glycogen-maintained ATP in the brain is a possible defense mechanism for neurons in the exhausted brain.
Ramadan fasting and non-insulin-dependent diabetes: effect on metabolic control.

The effect of fasting during the holy month of Ramadan on the metabolic control of 39 patients with overweight and non-insulin-dependent diabetes (NIDD) was studied. There were 29 females and 10 males with a mean age of 51.5 +/- 1.65 years and body mass index of 31.5 +/- 0.98 kg/m2. All were treated with diet and oral hypoglycaemic agents (OHA). There was no change in body weight, fasting plasma glucose, glycosylated haemoglobin (HbA1), C-peptide and insulin blood levels at the end of fasting. Total blood cholesterol concentration rose significantly (p 0.05) but not triglycerides at the end of Ramadan. There were no acute metabolic complications (e.g. hypoglycaemia) in the present study. We conclude that fasting during Ramadan is generally safe in NIDD. However, patients should be advised to make use of this opportunity to combine the spiritual benefit with improvement in the metabolic control of the diabetes mainly through weight reduction.
The effect of an arm sling on energy consumption while walking in hemiplegic patients: a randomized comparison

Objective: To evaluate the effect of an arm sling on gait speed and energy efficiency of patients with hemiplegia. Design: A randomized crossover design. Setting: A rehabilitation department of a university hospital. Subjects: Thirty-seven outpatients with hemiplegia were included in this study. Interventions: All patients walked on a 20-m walkway twice on the same day, randomly with and without an arm sling, at a self selected speed. Main measures: The heart rate, gait speed, oxygen cost and oxygen rate were measured on all patients. We analysed all values with and without an arm sling and also compared them after all patients being stratified according to demographic and clinical characteristics. Results: When we compared the heart rate between walking with (90.7 ± 17.2 beats/min) and without (91.2 ± 18.6 beats/min) the arm sling, it was significantly decreased while walking with the arm sling. When we compared the gait speed between walking with (32.8 m/min) and without (30.1 m/min), it was significantly increased with the arm sling walking. The O2 rate in hemiplegic patients walking with the arm sling was significantly decreased by 7%, compared to walking without arm sling (5.8 mL/kg min and 6.2 mL/kg min, respectively). The O2 cost in hemiplegic patients walking without arm sling was significantly 1.4 times greater than walking with it (0.2 mL/kg m and 0.3 mL/kg m, respectively). Conclusion: An arm sling can be used to improve the gait efficiency.
Prioritizing Test Cases for Regression Testing of Location-Based Services: Metrics, Techniques, and Case Study

Location-based services (LBS) are widely deployed. When the implementation of an LBS-enabled service has evolved, regression testing can be employed to assure the previously established behaviors not having been adversely affected. Proper test case prioritization helps reveal service anomalies efficiently so that fixes can be scheduled earlier to minimize the nuisance to service consumers. A key observation is that locations captured in the inputs and the expected outputs of test cases are physically correlated by the LBS-enabled service, and these services heuristically use estimated and imprecise locations for their computations, making these services tend to treat locations in close proximity homogenously. This paper exploits this observation. It proposes a suite of metrics and initializes them to demonstrate input-guided techniques and point-of-interest (POI) aware test case prioritization techniques, differing by whether the location information in the expected outputs of test cases is used. It reports a case study on a stateful LBS-enabled service. The case study shows that the POI-aware techniques can be more effective and more stable than the baseline, which reorders test cases randomly, and the input-guided techniques. We also find that one of the POI-aware techniques, cdist, is either the most effective or the second most effective technique among all the studied techniques in our evaluated aspects, although no technique excels in all studied SOA fault classes.