Miracle-dz/UniFAR-FTUs huggingface dataset:
Mining New Business Opportunities: Identifying Trend related Products by Leveraging Commercial Intents from Microblogs

Hot trends are likely to bring new business opportunities. For example, “Air Pollution” might lead to a significant increase of the sales of related products, e.g., mouth mask. For ecommerce companies, it is very important to make rapid and correct response to these hot trends in order to improve product sales. In this paper, we take the initiative to study the task of how to identify trend related products. The major novelty of our work is that we automatically learn commercial intents revealed from microblogs. We carefully construct a data collection for this task and present quite a few insightful findings. In order to solve this problem, we further propose a graph based method, which jointly models relevance and associativity. We perform extensive experiments and the results showed that our methods are very effective.
Detection of spatial correlations of fundamental plane residuals, and cosmological implications

The fundamental plane (FP) is a widely used tool to investigate the properties of early-type galaxies, and the tight relation between its parameters has spawned several cosmological applications, including its use as a distance indicator for peculiar velocity surveys and as a means to suppress intrinsic noise in cosmic size magnification measurements. Systematic trends with the large-scale structure across the FP could cause serious biases for these cosmological probes, but may also yield new insights into the early-type population. Here we report the first detection of spatial correlations among offsets in galaxy size from an FP that explicitly accounts for redshift trends, using a sample of about 95,000 elliptical galaxies from the Sloan Digital Sky Survey. We show that these offsets correlate with the density field out to at least 10h 1 Mpc at 4σ significance in a way that cannot be explained by systematic errors in galaxy size estimates. We propose a physical explanation for the correlations by dividing the sample into central, satellite, and field galaxies, identifying trends for each galaxy type separately. Central (satellite) galaxies lie on average above (below) the FP, which we argue could be due to a higher (lower) than average mass-to-light ratio. We fit a simple model to the correlations of FP residuals and use it to predict the impact on peculiar velocity power spectra, finding a contamination larger than 10% for k > 0.04h/Mpc. Moreover, cosmic magnification measurements based on an FP could be severely contaminated over a wide range of scales by the intrinsic FP correlations.
Cased borehole effects on downhole seismic measurements

Both approximate and exact formulations for the interaction of an incident elastic wave with a cased borehole are presented. In the approximate method, simple and explicit formulae are derived for the pressure in fluid at low frequencies. In the exact method, elastic potentials in each annulus are presented as a superposition of fundamental solutions to the Helmholtz equations. Continuity of displacements and stresses across layer boundaries are used to determine unknown coefficients. A global matrix algorithm is employed to compute simultaneously these coefficients in individual layers. Calculations show that, in cased boreholes, the borehole effects on downhole seismic measurements are more significant than in open boreholes. A strong resonance occurs in the fluid for SV-wave incidence from a soft formation. This resonance is prominent even at very high frequencies because the tube-wave velocity is raised well above the formation shear velocity by the steel pipe. At a particular angle of incidence of a plane P-wave, the pressure in the fluid is near zero at low frequencies (the cased borehole screening phenomenon). For hard formations and frequencies above 1 kHz, the cased borehole influence on a downhole geophone measurement is significant, especially at grazing incidence. For soft formations, both the pressuremore » in the fluid and the solid displacement on the borehole wall show strong dependence on frequency and angle of incidence, even at low frequencies. « less
Fear, Populism, and the Geopolitical Landscape

Two recent electoral results—Donald Trump’s election as U.S. president and the UK’s Brexit vote—have reignited debate on the psychological factors underlying voting behavior. Both campaigns promoted themes of fear, lost pride, and loss aversion, which are relevant to the personality dimension of neuroticism, a construct previously not associated with voting behavior. To that end, we investigate whether regional prevalence of neurotic personality traits (neuroticism, anxiety, and depression) predicted voting behavior in the United States (N = 3,167,041) and the United Kingdom (N = 417,217), comparing these effects with previous models, which have emphasized the roles of openness and conscientiousness. Neurotic traits positively predicted share of Brexit and Trump votes, and Trump gains from Romney. Many of these effects persisted in additional robustness tests controlling for regional industrial heritage, political attitude, and socioeconomic features, particularly in the United States. The “sleeper effect” of neurotic traits may profoundly impact the geopolitical landscape.
Comparison of leukotriene B4 and D4 effects on human eosinophil and neutrophil motility in vitro

The motility of isolated normal human peripheral blood eosinophils and neutrophils in response to exogenous leukotrienes B4 and D4 was examined by means of a modified under‐agarose technique and a novel quantitative sampling strategy. Leukotriene D4 was a potent chemoattractant for eosinophils, with a significant threshold chemotactic effect evident at 10‐10 M. The abolition of eosinophil chemotaxis by the potent and selective peptide‐leukotriene‐antagonist SK&F 104353 indicated the pharmacological specificity of the leukotriene D4‐induced response. The chemokinetic response of eosinophils to leukotriene D4 generally did not differ significantly from spontaneous migratory activity of unstimulated cells. Leukotriene D4 did not, however, alter directed neutrophil motility until a very high concentration (10‐5 M) was achieved, although significant neutrophil chemokinesis relative to unstimulated movement was observed over the tested concentration range. Directional emigration of both eosinophils and neutrophils was induced by leukotriene B4 at concentrations as low as 10‐8 M. Analysis of leukocyte orientations provided evidence that chemokinetic responses were not being interpreted as indications of chemotactic behavior. These studies suggest that leukotriene D4 may behave as a potent and selective chemoattractant for human eosinophils at physiologically relevant concentrations. J. Leukoc. Biol. 55: 183–191; 1994.
Core promoter factor TAF9B regulates neuronal gene expression

Emerging evidence points to an unexpected diversification of core promoter recognition complexes that serve as important regulators of cell-type specific gene transcription. Here, we report that the orphan TBP-associated factor TAF9B is selectively up-regulated upon in vitro motor neuron differentiation, and is required for the transcriptional induction of specific neuronal genes, while dispensable for global gene expression in murine ES cells. TAF9B binds to both promoters and distal enhancers of neuronal genes, partially co-localizing at binding sites of OLIG2, a key activator of motor neuron differentiation. Surprisingly, in this neuronal context TAF9B becomes preferentially associated with PCAF rather than the canonical TFIID complex. Analysis of dissected spinal column from Taf9b KO mice confirmed that TAF9B also regulates neuronal gene transcription in vivo. Our findings suggest that alternative core promoter complexes may provide a key mechanism to lock in and maintain specific transcriptional programs in terminally differentiated cell types. DOI: http://dx.doi. org/10.7554/eLife.02559. 001
OXPHOS Supercomplexes as a Hallmark of the Mitochondrial Phenotype of Adipogenic Differentiated Human MSCs

Mitochondria are essential organelles with multiple functions, especially in energy metabolism. Recently, an increasing number of data has highlighted the role of mitochondria for cellular differentiation processes. Metabolic differences between stem cells and mature derivatives require an adaptation of mitochondrial function during differentiation. In this study we investigated alterations of the mitochondrial phenotype of human mesenchymal stem cells undergoing adipogenic differentiation. Maturation of adipocytes is accompanied by mitochondrial biogenesis and an increase of oxidative metabolism. Adaptation of the mt phenotype during differentiation is reflected by changes in the distribution of the mitochondrial network as well as marked alterations of gene expression and organization of the oxidative phosphorylation system (OXPHOS). Distinct differences in the supramolecular organization forms of cytochrome c oxidase (COX) were detected using 2D blue native (BN)-PAGE analysis. Most remarkably we observed a significant increase in the abundance of OXPHOS supercomplexes in mitochondria, emphasizing the change of the mitochondrial phenotype during adipogenic differentiation.
Underwater noise measurements of a 1/7th scale wave energy converter

Field measurements of the underwater acoustic signature of Columbia Power Technologies (Columbia Power) SeaRay wave energy converter (WEC) prototype are presented. The device was deployed in the vicinity of West Point (Puget Sound, Washington State) at a depth of approximately 20 meters. The 1/7th scale SeaRay prototype is a heave and surge, point absorber secured to the seabed with a three-point mooring. Acoustic measurements were made in order to satisfy permit requirements and assure that marine life is not adversely affected.
Linearized Alternating Direction Method with Gaussian Back Substitution for Separable Convex Programming

Recently, we have proposed to combine the alternating direction method (ADM) with a Gaussian back substitution procedure for solving the convex minimization model with linear constraints and a general separable objective function, i.e., the objective function is the sum of many functions without coupled variables. In this paper, we further study this topic and show that the decomposed subproblems in the ADM procedure can be substantially alleviated by linearizing the involved quadratic terms arising from the augmented Lagrangian penalty on the model's linear constraints. When the resolvent operators of the separable functions in the objective have closed- form representations, embedding the linearization into the ADM subproblems becomes necessary to yield easy subproblems with closed-form solutions. We thus show theoretically that the blend of ADM, Gaussian back substitution and linearization works effectively for the separable convex minimization model under consideration.
Intergenerational Mobility in Britain

In this paper we use longitudinal data on children and their parents to assess the extent of intergenerational mobility in Britain. Based on data from the National Child Development Survey, a cohort of all individuals born in a week of March 1958, we find that the extent of intergenerational mobility is limited. We report an intergenerational correlation of the order . 40 to.60 for fathers and sons and . 45 to.70 for fathers and daughters in terms of labour market earnings and years of schooling. An examination of quartile transition matrices between parental and child earnings outcomes reveals a similar pattern. Finally, it seems, on the basis of these transition matrices, that there is an important asymmetry in intergenerational earnings mobility with upward mobility from the bottom, of the earnings distribution being more likely than downward mobility from the top.
Job Growth in Early Transition: Comparing Two Paths

Small start-up firms are the engine of job creation in early transition. We ask about differences in their growth across two different transition economies: Estonia, which experienced rapid destruction of pre-existing firms, and the Czech Republic, which reduced the old sector gradually. We find that the majority of job growth corresponds to within-industry reallocation. The within-industry growth of small start-up firms is similar in the two countries, in line with the convergence to Western industry firm-size distributions. We also find similar patterns in the evolution of wage differentials between start-ups and old firms and small differences in the extent of low-wage employment in start-ups across the two transition paths.
Occupation-based practice in a tertiary hospital setting: occupational therapists’ perceptions and experiences

Occupation-based practice is an important feature of occupational therapy. There is however limited research regarding occupational therapists’ experiences with occupation-based practice. This study aimed to explore occupational therapists’ perceptions and experiences regarding occupation-based practice in a tertiary hospital setting in the Western Cape, South Africa. An explorative and descriptive research design within a qualitative research approach was utilised. Purposive sampling allowed the selection of fourt participants with a minimum of 2 years practice experience. Semi-structured interviews were conducted to gain an understanding of how they perceived and implemented occupation-based practice. Data were analysed using thematic analysis. Four themes emerged: occupation-based practice expresses professional identity; occupation-based practice necessitates relevance; constraints to occupation-based practice; and facilitators of occupation-based practice. The findings revealed that the participants’ perceived the implementation of occupation-based practice as an expression of their professional identity and that in adopting an occupation-based approach they perceived their roles as diverse and transformational. It was however highlighted that the nature of the service context posed several constraints that influenced the implementation of occupation-based practice. Thus, occupational therapists may need to generate practice-based evidence to advocate for the service conditions necessary to implement occupation-based practice and deliver relevant occupational therapy services. Key words : Occupation; occupation-based practice; tertiary hospitals; qualitative research
Model-Based Clustering using multi-allelic loci data with loci selection

We propose a Model-Based Clustering (MBC) method combined with loci selection using multi-allelic loci genetic data. The loci selection problem is regarded as a model selection problem and models in competition are compared with the Bayesian Information Criterion (BIC). The resulting procedure selects the subset of clustering loci, the number of clusters, estimates the proportion of each cluster and the allelic frequencies within each cluster. We prove that the selected model converges in probability to the true model under a single realistic assumption as the size of the sample tends to infinity. The proposed method named MixMoGenD (Mixture Model using Genetic Data) was implemented using c++ programming language. Numerical experiments on simulated data sets was conducted to highlight the interest of the proposed loci selection procedure.
Advances in microRNAs: implications for immunity and inflammatory diseases

• Introduction ‐ Overview and history ‐ The biogenesis of miRNAs ‐ Mechanism of action of miRNAs • Identification of microRNA targets • Multi‐level control of microRNA expression • How can microRNAs contribute to diseases? • MiRNAs in immunological and inflammatory disorders ‐ Psoriasis and atopic eczema ‐ Asthma ‐ Rheumatoid arthritis ‐ Systemic lupus erythematosus ‐ Primary biliary cirrhosis ‐ MiR‐17–5p and miR‐101 in autoimmunity ‐ Vascular inflammation • MiRNAs in antiviral immunity and viral immune escape ‐ Viral miRNAs regulating host genes ‐ Viral miRNAs regulating viral genes ‐ Host miRNAs regulating viral genes • Perspectives
ABO and Rhesus Blood Groups and Risk of Endometriosis in a French Caucasian Population of 633 Patients Living in the Same Geographic Area

Objectives. The identification of epidemiological factors increasing the risk of endometriosis could shorten the time to diagnosis. Specific blood groups may be more common in patients with endometriosis. Study Design. We designed a cross-sectional study of 633 Caucasian women living in the same geographic area. Study group included 311 patients with histologically proven endometriosis. Control group included 322 patients without endometriosis as checked during surgery. Frequencies of ABO and Rhesus groups in the study and control groups were compared using univariate and multivariate analyses. Results. We observed a higher proportion of Rh-negative women in the study group, as compared to healthy controls. Multivariate analysis showed that Rh-negative women are twice as likely to develop endometriosis (aOR = 1.90; 95% CI: 1.20–2.90). There was no significant difference in ABO group distribution between patients and controls. There was no difference when taking into account either the clinical forms (superficial endometriosis, endometrioma, and deep infiltration endometriosis) or the rAFS stages. Conclusion. Rh-negative women are twice as likely to develop endometriosis. Chromosome 1p, which contains the genes coding for the Rhesus, could also harbor endometriosis susceptibility genes.
Plasma Growth Differentiation Factor-15 Independently Predicts All-Cause and Cardiovascular Mortality As Well As Deterioration of Kidney Function in Type 1 Diabetic Patients With Nephropathy

OBJECTIVE Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decline in glomerular filtration rate (GFR), and progression toward end-stage renal disease (ESRD). RESEARCH DESIGN AND METHODS The study was a prospective observational follow-up study including 451 type 1 diabetic patients with diabetic nephropathy (274 men, aged 42.1 ± 0.5 years [means ± SD], diabetes duration 28.3 ± 8.9 years, GFR 76 ± 33 ml/min/1.73 m2) and a control group of 440 patients with longstanding type 1 diabetes and persistent normoalbuminuria (232 men, aged 45.4 ± 11.5 years, duration of diabetes 27.7 ± 10.1 years). The patients were followed for 8.1 (0.0–12.9) years (median [range]). RESULTS Among normoalbuminuric patients, GDF-15 above the median predicted an adjusted (age, systolic blood pressure [sBP], and estimated GFR) increased risk of all-cause mortality (hazard ratio [HR] 3.6 [95% CI 1.3–10.3]; P = 0.014). Among patients with diabetic nephropathy, higher (fourth quartile) versus lower (first quartile) GDF-15 levels predict all-cause mortality (covariate-adjusted [sex, age, smoking, blood pressure, A1C, cholesterol, GFR, N-terminal prohormone B-type natriuretic peptide, antihypertensive treatment, and previous cardiovascular events]; HR 4.86 [95% CI 1.37–17.30]) as well as fatal and nonfatal cardiovascular events (adjusted HR 5.59 [1.23–25.43] and 3.55 [1.08–11.64], respectively). In addition, higher GDF-15 levels predict faster decline in GFR (P < 0.001) but not development of ESRD. CONCLUSIONS Higher levels of GDF-15 are a predictor of all-cause and cardiovascular mortality and morbidity in patients with diabetic nephropathy. Furthermore, higher levels of GDF-15 are associated with faster deterioration of kidney function.
Time course of cigarette smoke-induced pulmonary inflammation in mice

Inflammation of the airways and lung parenchyma plays a major role in the pathogenesis of chronic obstructive pulmonary disease. In the present study a murine model of tobacco smoke-induced emphysema was used to investigate the time course of airway and pulmonary inflammatory response, with a special emphasis on pulmonary dendritic cell (DC) populations. Groups of mice were exposed to either cigarette smoke or to control air for up to 24 weeks. In response to cigarette smoke, inflammatory cells (i.e. neutrophils, macrophages and lymphocytes) progressively accumulated both in the airways and lung parenchyma of mice. Furthermore, a clear infiltration of DCs was observed in airways (10-fold increase) and lung parenchyma (1.5-fold increase) of cigarette-exposed mice at 24 weeks. Flow cytometric analysis of bronchoalveolar lavage (BAL) DCs of smoke-exposed mice showed upregulation of major histocompatability complex II molecules and costimulatory molecules CD40 and CD86, compared with BAL DCs of air-exposed mice. Morphometric analysis of lung histology demonstrated a significant increase in mean linear intercept and alveolar wall destruction after 24 weeks of smoke exposure. In conclusion, the time course of the changes in inflammatory and dendritic cells in both bronchoalveolar lavage and the pulmonary compartment of cigarette smoke-exposed mice was carefully characterised.
Selection for cuticular melanism reveals immune function and life‐history trade‐offs in Spodoptera littoralis

Several insect species show an increase in cuticular melanism in response to high densities. In some species, there is evidence that this melanism is correlated with an up‐regulation of certain immune system components, particularly phenoloxidase (PO) activity, and with the down‐regulation of lysozyme activity, suggesting a trade‐off between the two traits. As melanism has a genetic component, we selected both melanic and nonmelanic lines of the phase‐polyphenic lepidopteran, Spodoptera littoralis, in order to test for a causative genetic link between melanism, PO activity and lysozyme activity, and to establish if there are any life‐history costs associated with the melanic response. We found that, in fact, melanic lines had lower PO activity and higher lysozyme activity than nonmelanic lines, confirming a genetic trade‐off between the two immune responses, but also indicating a genetic trade‐off between melanism and PO activity. In addition, we found that lines with high PO activity had slower development rates suggesting that investment in PO, rather than in melanism, is costly.
The Relationship between Learner Motivation and Vocabulary Size: The Case of Iraqi EFL Classrooms

This study investigates the relationship between learner motivation and vocabulary size in English as foreign language (EFL) classrooms at Duhok University. The participants included 100 students (55 male, 45 female). All participants were pursuing their third years of study in an English department. Two instruments were employed: questionnaires regarding Motivation for Foreign Language Learning (MFLL) and Vocabulary Size Test (VST). The primary goal of this study is to determine which factors of motivation profoundly affect the foreign language learning processes of Iraqi EFL students and to what extent they should develop their depth and breadth English vocabularies in order to sufficiently acquire the language and elaborate the importance of both components in language acquisition. Findings showed that female students experienced both types of motivation, with the mean score of extrinsic motivation being 29.91, and that for intrinsic motivation being 31.20, while the mean score of male students was 27.10 for extrinsic motivation and 28.00 for intrinsic motivation. The VST ranged from 1,000 to 14,000 wordfamilies, and the vocabulary size of both groups was over 6,000 word-families. Correlation analysis was conducted to determine the relationship between learner motivation and vocabulary size. For both groups, the results indicated no relationship between these two aspects of students' foreign language leaning. To investigate the difference between MFLL and VST, an independent samples t-test was utilized and no difference was found to exist between the vocabularies of both groups.