Miracle-dz/UniFAR-FTUs huggingface dataset:
Legitimate Voices: A Multi-Case Study of Trans and Non-Binary Singers in the Applied Voice Studio

LEGITIMATE VOICES: A MULTI-CASE STUDY OF TRANS AND NON-BINARY SINGERS IN THE APPLIED VOICE STUDIO William R. Sauerland This qualitative, multi-case study examined trans and non-binary singers in the applied voice studio. The purpose of this study was to explore (1) the impact of music participation on the identities of trans and non-binary singers, (2) the experiences of trans and non-binary singers taking private singing lessons, and (3) the strategies and practices of their voice teachers. Purposeful sampling of four singers included two trans men and two non-binary individuals. Four teachers with prior experience in teaching trans or nonbinary singers included two teachers identifying as trans men, and two cisgender (one female, one male) teachers. Data were collected through interviews and lesson observations, presented through portraiture analysis to provide an insider’s view of the experiences, perspectives, and practices of the participants. Findings and implications emerged through cross-case analyses. The results indicate that gender impacts musical spaces. While participation in musical activities created an outlet for some singers to explore their trans or non-binary identity, the reification of the gender binary in musical spaces was oppressive for others. Students modeled high self-efficacy by showing perceived competence to change discriminatory policies and practices in music and the performing arts. Teachers demonstrated emotional support in the applied studio by being cognizant of student needs. While the training of each student looked distinct, teachers affirmed students through student-centered pedagogical approaches, allowing students to guide their vocal training and development. Teachers discussed the need for adept understanding of vocal technique in training trans and non-binary singers. All four trans men (two students and two teachers) discussed their voice modification through testosterone replacement therapy. The two non-binary singers, not engaged in medical voice modulation, discussed changes in their voices through singing lessons. The research posits that curricular development in vocal pedagogy courses is needed to educate singing teachers on cultural competency and trans and non-binary vocality. This study revealed the need to examine applied teacher readiness in educating trans and non-binary singing. Research on the longitudinal effects of testosterone on the voice is warranted. Additional scholarship is needed in working with trans or non-binary voices not engaging in hormone replacement therapy.
Display Optimization in SSVEP BCIs

INTRODUCTION Brain – computer interface (BCI) systems allow people to send information without moving [1]. Some BCIs rely on the Steady State Visual Evoked Potential (SSVEP), a type of EEG activity that occurs when subjects focus attention on a stimulus that oscillates between about 5-40 Hz. Thus, the efficacy of an SSVEP BCI depends on how quickly and effectively it can distinguish SSVEP activity that reflects user attention from background noise. This depends on many factors, including EEG signal quality, task and display parameters, signal processing approaches, and user factors. SSVEP BCIs often utilize stimuli containing oscillating checkerboxes. Figure 1 below shows four examples of such displays [2][3][4][5]. In these BCIs, subjects direct attention to one of the oscillating checkerboxes to convey interest in a corresponding region. Thus, directing attention to the left checkerbox would move a game character, map, car, or cursor. It is also possible for subjects to focus attention on two targets, which could improve information throughput by increasing the number of commands available to a user [6].
Archaeal Enzymes and Applications in Industrial Biocatalysts

Archaeal enzymes are playing an important role in industrial biotechnology. Many representatives of organisms living in “extreme” conditions, the so-called Extremophiles, belong to the archaeal kingdom of life. This paper will review studies carried by the Exeter group and others regarding archaeal enzymes that have important applications in commercial biocatalysis. Some of these biocatalysts are already being used in large scale industrial processes for the production of optically pure drug intermediates and amino acids and their analogues. Other enzymes have been characterised at laboratory scale regarding their substrate specificity and properties for potential industrial application. The increasing availability of DNA sequences from new archaeal species and metagenomes will provide a continuing resource to identify new enzymes of commercial interest using both bioinformatics and screening approaches.
Leadership training and emotional intelligence in school nurses

Leadership Training and Emotional Intelligence in School Nurses by Anne L. Diaz Dr. Cheryl Bowles, Examination Committee Chair Professor o f Nursing University of Nevada, Las Vegas Now more than ever, nurses need to be leaders. However, most studies of leadership, whether in nursing, business, or the military, have focused on individuals in administrative positions. School nurses practice in primarily autonomous circumstances, where they need to possess substantial leadership skills and the ability to identify and manage emotions to ensure an optimal educational learning environment for the students under their care. Three leadership theories were combined to form the Emotionally Intelligent Leadership Model as the framework for a leadership training program. This two group before and after quasi-experimental study investigated the effects of a leadership training program on the emotional intelligence and perceptions of leadership skills o f school nurses. A sample o f 60 school nurses in Southern Nevada were recruited and randomly assigned to either the control or experimental group. The experimental group
PENGARUH E-SERVICE QUALITY TERHADAP E-SATISFACTION PADA PENGGUNA DI SITUS TOKOPEDIA

Sebagai bisnis yang berorientasi pada konsumen, maka dalam e-commerce kepuasan konsumen online adalah hal yang utama, yang dapat diwujudkan dengan adanya kualitas pelayanan online yang baik dari perusahaan. Maka penting diadakannya penelitian ini, dengan tujuan untuk mengetahui pengaruh e-service quality terhadap e-satisfaction . Selain itu juga, penelitian ini dilakukan untuk mengukur penilaian pembeli terhadap e-service quality , dan e- satisfaction di situs Tokopedia. Penelitian ini menggunakan metode kuantitatif, dan pengumpulan data dilakukan dengan cara penyebaran angket secara online, kepada pembeli di situs Tokopedia yang telah melakukan transaksi minimal 2 kali, dengan jumlah sampel sebanyak 137 orang. Teknik penarikan sampel yaitu nonprobability sampling dengan teknik analisis menggunakan regresi linier sederhana. Hasil yang diperoleh pada penelitian ini adalah e-service quality berpengaruh positif dan signifikan terhadap e-satisfaction di situs Tokopedia.
A Portfolio Approach to Venture Capital Financing

This paper studies the contracting choices between an entrepreneur and venture capital investors in a portfolio context. We rely on the mean-variance framework and derive the optimal choices for an entrepreneur with and without the presence of different kinds of venture capitalists. In particular, we show that the entrepreneur always has the incentive to share the risk and benefits of the venture whenever possible. On the basis of their objectives and characteristics, we distinguish the situations of the corporate, independent, and bank-sponsored venture capital funds. Our framework enables us to derive the optimal contract design for the entrepreneur, featuring the choice of investor, the entrepreneur’s investment in the venture, and her dilution in the project’s equity as a function of her bargaining power. This result allows us to characterize the choice of the investor depending on her cost of equity and debt capital. In addition to project size and risk, entrepreneur’s risk aversion turns out to be a critical determinant of VC investor choice –a finding which is strongly supported by a panel analysis of VC fund flows for 5 European countries over the 2002-2009 period.
A Fast Biologically Inspired Algorithm for Recurrent Motion Estimation

We have previously developed a neurodynamical model of motion segregation in cortical visual area V1 and MT of the dorsal stream. The model explains how motion ambiguities caused by the motion aperture problem can be solved for coherently moving objects of arbitrary size by means of cortical mechanisms. The major bottleneck in the development of a reliable biologically inspired technical system with real-time motion analysis capabilities based on this neural model is the amount of memory necessary for the representation of neural activation in velocity space. We propose a sparse coding framework for neural motion activity patterns and suggest a means by which initial activities are detected efficiently. We realize neural mechanisms such as shunting inhibition and feedback modulation in the sparse framework to implement an efficient algorithmic version of our neural model of cortical motion segregation. We demonstrate that the algorithm behaves similarly to the original neural model and is able to extract image motion from real world image sequences. Our investigation transfers a neuroscience model of cortical motion computation to achieve technologically demanding constraints such as real-time performance and hardware implementation. In addition, the proposed biologically inspired algorithm provides a tool for modeling investigations to achieve acceptable simulation time
Surgical Ablation of Atrial Fibrillation in Patients Undergoing Bioprosthetic Valve Replacement

Background Scarce data have been reported on the efficacy of concomitant atrial fibrillation (AF) ablation in patients undergoing bioprosthetic valve replacement. Methods From 2001 and 2014, 146 consecutive patients (69.3±9.4 years, 84 females) who underwent bioprosthetic heart valve replacement concomitant with AF ablation were assessed. We evaluated long-term rhythm and valve-related outcomes. Results During 49.1 months of follow-up (interquartile range, 22.5–96.8 months), 7 in-hospital and 49 (6.7% per person-year) post-discharge deaths occurred. The thromboembolic event-free survival rate at 5 years was 79.2%±3.5%. The freedom from AF recurrence rate at 5 years was 59.8%±4.9%. Multivariate analysis showed that old age (hazard ratio [HR], 1.06; 95% confidence interval [CI], 1.02–1.11; p=0.002), previous cardiac operation (HR, 3.01; 95% CI, 1.22–7.43; p=0.02), and a large left atrial (LA) dimension (HR, 1.02; 95% CI, 1.00–1.05; p=0.045) were significantly associated with AF recurrence. Conclusion The overall long-term clinical outcomes in these predominantly elderly patients undergoing AF ablation concomitantly with bioprosthetic valve replacement were satisfactory; however, AF recurrence was frequent. Older age, a history of prior cardiac surgery, and large LA size were associated with an increased risk of AF recurrence.
NMDA-Mediated Activation of the Medial Amygdala Initiates a Downstream Neuroendocrine Memory Responsible for Pseudopregnancy in the Female Rat

In female rats, genitosensory stimulation received during mating initiates twice-daily prolactin (PRL) surges, a neuroendocrine response that is the hallmark of early pregnancy or pseudopregnancy (P/PSP). Nocturnal and diurnal PRL surges are expressed repeatedly for up to 2 weeks after copulation, suggesting that a neuroendocrine memory for vaginocervical stimulation (VCS) is established at the time of mating. These studies investigated whether the processing and retention of VCS involves acute glutamatergic activation or de novoprotein synthesis within the medial nucleus of the amygdala (MEA), a VCS-responsive brain site that is implicated in P/PSP initiation. Pharmacological activation of the MEA with the glutamate agonist, NMDA, initiated nocturnal PRL surges, causing a PSP state in females that had not received VCS. P/PSP initiation by mating was prevented by intra-amygdalar infusion of the NMDA receptor antagonist, 2-amino-5-phosphonopentanoic acid (AP-5), provided that it was administered before mating. AP-5 treatment also disrupted mating-induced c-fos expression in the principle bed nucleus of the stria terminalis and the ventrolateral division of the ventromedial hypothalamic nucleus, but not in the medial or anteroventral periventricular preoptic nuclei. Neither P/PSP nor downstream cellular activation was prevented when a protein synthesis inhibitor, anisomycin, was administered to the MEA. The results indicate that MEA cells are critical to the early processing of VCS through NMDA channel activation, rapidly conveying information to downstream hypothalamic cell groups that modulate neuroendocrine function.
Social Patterns In Normal Aging

When writing can change your life, when writing can enrich you by offering much money, why don't you try it? Are you still very confused of where getting the ideas? Do you still have no idea with what you are going to write? Now, you will need reading. A good writer is a good reader at once. You can define how you write depending on what books to read. This social patterns in normal aging can help you to solve the problem. It can be one of the right sources to develop your writing skill.
FDTD Analysis of Retinal Photoreceptor Outer-Segment : Effect of Stacking Nano-Layers of Membrane and Cytoplasm

This paper presents finite-difference time-domain (FDTD) analysis of the retinal photoreceptor outer-segment. Our model simulates, in an optical sense, the reaction of the photoreceptor to the visible light spectrum. We consider a broadband pulse excitation to examine the mode coupling. Our investigations include the variations of Poynting power versus wavelength at exiting cross-sections of the outer-segment, and for varying incident angles of the impinging wave. In order to study the role of the stacking nano-layers of the cytoplasm and membrane which comprise the inner photoreceptor anatomy, the results are compared with those obtained from an averaged-permittivity model of the outersegment.
The type 1 polyaxonal amacrine cells of the rabbit retina: A tracer-coupling study

The type 1 polyaxonal (PA1) cell is a distinct type of axon-bearing amacrine cell whose soma commonly occupies an interstitial position in the inner plexiform layer; the proximal branches of the sparse dendritic tree produce 1–4 axon-like processes, which form an extensive axonal arbor that is concentric with the smaller dendritic tree (Dacey, 1989; Famiglietti, 1992a,b). In this study, intracellular injections of Neurobiotin have revealed the complete dendritic and axonal morphology of the PA1 cells in the rabbit retina, as well as labeling the local array of PA1 cells through homologous tracer coupling. The dendritic-field area of the PA1 cells increased from a minimum of 0.15 mm2 (0.44-mm equivalent diameter) on the visual streak to a maximum of 0.67 mm2 (0.92-mm diameter) in the far periphery; the axonal-field area also showed a 3-fold variation across the retina, ranging from 3.1 mm2 (2.0-mm diameter) to 10.2 mm2 (3.6-mm diameter). The increase in dendritic- and axonal-field size was accompanied by a reduction in cell density, from 60 cells/mm2 in the visual streak to 20 cells/mm2 in the far periphery, so that the PA1 cells showed a 12 times overlap of their dendritic fields across the retina and a 200–300 times overlap of their axonal fields. Consequently, the axonal plexus was much denser than the dendritic plexus, with each square millimeter of retina containing ∼100 mm of dendrites and ∼1000 mm of axonal processes. The strong homologous tracer coupling revealed that ∼45% of the PA1 somata were located in the inner nuclear layer, ∼50% in the inner plexiform layer, and ∼5% in the ganglion cell layer. In addition, the Neurobiotin-injected PA1 cells sometimes showed clear heterologous tracer coupling to a regular array of small ganglion cells, which were present at half the density of the PA1 cells. The PA1 cells were also shown to contain elevated levels of γ-aminobutyric acid (GABA), like other axon-bearing amacrine cells.
Improving WWW Proxies Performance with Greedy-Dual- Size-Frequency Caching Policy

Web, HTTP, WWW proxies, caching policies, replacement algorithms, performance Web proxy caches are used to improve performance of the WWW. Since the majority of Web documents are static documents, caching them at WWW proxies reduces both network traffic and response time. One of the keys to better proxy cache performance is an efficient caching policy which keeps in the cache popular documents and replaces rarely used ones. This paper introduces the Greedy-Dual-Size-Frequency caching policy to maximize hit and byte hit rates for WWW proxies. Proposed caching strategy incorporates in a simple way the most important characteristics of the file and its accesses such as file size, file access frequency and recentness of the last access. Greedy-Dual-Size-Frequency is an improvement of Greedy-Dual-Size algorithm – the current champion among the replacement strategies proposed for Web proxy caches.
Valuation and Initial Return of Initial Public Offerings : Role of Discretionary Accounting Accruals

This study examines the role of pre-IPO discretionary accruals in the valuation and first day initial returns of IPOs. We find that IPO offer price is unaffected whereas market closing price is positively associated with the levels of pre-IPO discretionary accruals for issuers with aggressively reported earnings. We also find that this relative over-valuation of managed earnings by the markets explains a portion of the initial return that is not explained by other known determinants. For issuers with conservatively reported pre-IPO earnings, there is no relation between discretionary accruals and the offer price or the market price, and the discretionary accruals do not explain any IPO initial return. Our subsequent analysis shows that stock retention appears to be a screen and a signal of entrepreneurs’ credibility to the markets. There seems to be a higher degree of earnings scrutiny by both the markets and the underwriters for IPOs with low entrepreneurial (insider) retention. However, markets tend to assign higher weight to reported earnings of issuers with higher insider retention, presumably because of perceived incentive alignment. Underwriters, with relatively lesser information asymmetry than the markets, tend to see through the distortions caused by earnings manipulations in the valuation of IPOs, regardless of the levels of issuers’ stock retention.
Benthic primary production in an upwelling-influenced coral reef, Colombian Caribbean

In Tayrona National Natural Park (Colombian Caribbean), abiotic factors such as light intensity, water temperature, and nutrient availability are subjected to high temporal variability due to seasonal coastal upwelling. These factors are the major drivers controlling coral reef primary production as one of the key ecosystem services. This offers the opportunity to assess the effects of abiotic factors on reef productivity. We therefore quantified primary net (Pn) and gross production (Pg) of the dominant local primary producers (scleractinian corals, macroalgae, algal turfs, crustose coralline algae, and microphytobenthos) at a water current/wave-exposed and-sheltered site in an exemplary bay of Tayrona National Natural Park. A series of short-term incubations was conducted to quantify O2 fluxes of the different primary producers during non-upwelling and the upwelling event 2011/2012, and generalized linear models were used to analyze group-specific O2 production, their contribution to benthic O2 fluxes, and total daily benthic O2 production. At the organism level, scleractinian corals showed highest Pn and Pg rates during non-upwelling (16 and 19 mmol O2 m−2 specimen area h−1), and corals and algal turfs dominated the primary production during upwelling (12 and 19 mmol O2 m−2 specimen area h−1, respectively). At the ecosystem level, corals contributed most to total Pn and Pg during non-upwelling, while during upwelling, corals contributed most to Pn and Pg only at the exposed site and macroalgae at the sheltered site, respectively. Despite the significant spatial and temporal differences in individual productivity of the investigated groups and their different contribution to reef productivity, differences for daily ecosystem productivity were only present for Pg at exposed with higher O2 fluxes during non-upwelling compared to upwelling. Our findings therefore indicate that total benthic primary productivity of local autotrophic reef communities is relatively stable despite the pronounced fluctuations of environmental key parameters. This may result in higher resilience against anthropogenic disturbances and climate change and Tayrona National Natural Park should therefore be considered as a conservation priority area.
Enhanced Production of IL-10 by Dendritic Cells Deficient in CIITA1

Dendritic cells (DC) are professional APCs that play a critical role in regulating immunity. In DC, maturation-induced changes in MHC class II expression and Ag presentation require transcriptional regulation by CIITA. To study the role of CIITA in DC, we evaluated key cell functions in DC from CIITA-deficient (CIITA−/−) mice. The ability to take up Ag, measured by fluid phase endocytosis, was comparable between CIITA−/− and control DC. Although CIITA−/− DC lack MHC class II, they maintained normal expression of costimulatory molecules CD80, CD86, and CD40. In contrast, CIITA−/− DC activated with LPS or CpG expressed increased IL-10 levels, but normal levels of TNF-α and IL-12 relative to control. Enhanced IL-10 was due to greater IL-10 mRNA in CIITA−/− DC. Aβ−/− DC, which lack MHC class II but express CIITA normally, had exhibited no difference in IL-10 compared with control. When CIITA was cotransfected with an IL-10 promoter-reporter into a mouse monocyte cell line, RAW 264.7, IL-10 promoter activity was decreased. In addition, reintroducing CIITA into CIITA−/− DC reduced production of IL-10. In all, these data suggest that CIITA negatively regulates expression of IL-10, and that CIITA may direct DC function in ways that extend beyond control of MHC class II.
Women entrepreneurs, individual and collective work–family interface strategies and emancipation

Purpose This paper aims to examine the experience of women entrepreneurs and the challenges and issues they face in reconciling the work activities of the family sphere with those of the entrepreneurial sphere. Design/methodology/approach This study is based on a materialist feminist perspective and a theory of living work that take into account the visible and invisible dimensions of the real work performed by women entrepreneurs. The methodology is based on a qualitative research design involving individual and group interviews conducted with 70 women entrepreneurs. Findings The results show the various individual and collective strategies deployed by women entrepreneurs to reconcile the work activities of the family and entrepreneurial spheres. Originality/value One of the major findings emerging from the results of this study relates to the re-appropriation of the world of work and organization of work by women entrepreneurs and its emancipatory potential for the division of labour. Through the authority and autonomy they possessed as business owners, and with their employees’ cooperation, they integrated and internalized tasks related to the work activities of the family sphere into the organization of work itself. Thus, not only new forms of work organization and cooperation at work but also new ways of conceiving of entrepreneurship as serving women’s life choices and emancipation could be seen to be emerging.