Miracle-dz/UniFAR-FTUs huggingface dataset:
Successful pregnancy during chemotherapy for acute leukemia

A 26‐year‐old patient with acute lymphatic leukemia conceived while on systemic chemotherapy. This patient experienced relapse during the second trimester, and a second complete hematologic remission was achieved with doxorubicin hydrochloride, vincristine, and prednisone. A 2400‐gram, but otherwise normal, male infant was delivered by Caesarean section during the 36th gestational week. Growth and development of this child is normal at six months. Cancer 47:845–846, 1981.
On the Value Function of a Mixed Integer Linear Optimization Problem and an Algorithm for its Construction

This paper addresses the value function of a general mixed integer linear optimization problem (MILP). The value function describes the change in optimal objective value as the right-hand side is varied and understanding its structure is central to solving a variety of important classes of optimization problems. We propose a discrete representation of the MILP value function and describe a cutting plane algorithm for its construction. We show that this algorithm is finite when the set of right-hand sides over which the value function of the associated pure integer optimization problem is finite is bounded. We explore the structural properties of the MILP value function and provide a simplification of the Jeroslow Formula obtained by applying our results.
La politique du terrain@@@The policy of fieldwork. On the production of data in anthropology: Sur la production des données en anthropologie

Le mode particulier de production de donnees qu’est l’enquete de terrain, en anthropologie (ou en sociologie dite parfois « qualitative »), passe pour l’essentiel par des interactions prolongees entre le chercheur en personne et le « milieu » qu’il etudie. C’est avant tout une question de savoir-faire, s’apprenant par la pratique, et non formalisable. Mais cette configuration methodologique specifique n’est pas pour autant sans principes, ni soumise aux seuls aleas de la subjectivite. Une « politique du terrain » soucieuse de repondre a des exigences de plausibilite et de validite doit se donner certains reperes, qu’on s’efforce ici de decrire, a travers les quatre grands types de donnees produites : (a) l’observation participante (observations et interactions engendrant des donnees de corpus et des donnees d’impregnation) ; (b) les entretiens (consultations et recits dans un registre conversationnel, a fonction recursive, relevant de « negociations invisibles ») ; (c) les dispositifs de recensions (procedures systematiques et intensives d’observation et de mesure) ; (d) les sources ecrites. A travers ces quatre types de donnees, le chercheur de terrain tente de construire tant bien que mal une « rigueur du qualitatif » qui navigue autour de quelques principes simples : la triangulation et la recherche empirique de groupes strategiques, l’iteration, l’explication interpretative, la construction de « descripteurs », la saturation de l’information, le groupe social temoin et enfin la gestion des biais subjectifs.
Gendered body ideals in Swedish competitive youth swimming: negotiating and shifting symbolic boundaries

Abstract This article explores how gendered body ideals are constructed and negotiated among 12 competitive youth swimmers in three Swedish clubs. Of particular interest are the ways boys and girls negotiate body ideals inside and outside of swimming contexts and how they shift gendered symbolic boundaries. The paper is framed by gender theory, and it draws on concepts of sport culture and social culture as well as symbolic boundaries. Interpretative repertoires were analysed to explore the language use in swimmers’ conversations related to the body and body ideals. Data were produced through interviews with competitive youth swimmers. My findings show that both girls and boys negotiate body ideals. The functional body was an interpretative repertoire important in the negotiations and shifting of gendered boundaries between the athletic body in sports and the aesthetic body in society. Swimmers also used an interpretative repertoire of similarity to negotiate symbolic gender boundaries. Furthermore, both identifying with a group and being accepted in that group are suggested to be important factors involved in shifting symbolic boundaries.
Human Nutrition and Metabolism Dietary Magnesium Depletion Affects Metabolic Responses during Submaximal Exercise in Postmenopausal Women 1 , 2

Magnesium is an essential mineral that is required for optimal biological function including energy metabolism. Although national nutritional surveys indicate that usual magnesium intakes do not meet recommendations, particularly among older women, diet-induced magnesium depletion is considered rare among humans without concurrent illness. We examined the effects of dietary magnesium restriction on biochemical measures of magnesium nutriture and physiologic responses during submaximal exercise in 10 postmenopausal women, 45–71 y old, not receiving hormone replacement therapy. The women consumed diets containing conventional foods with varying magnesium content totaling 112 mg/8.4 MJ (2000 kcal) supplemented with 200 mg magnesium daily for 35d (control), then 112 mg/8.4 MJ for 93d (depletion) followed by 112 mg/8.4 MJ supplemented with 200 mg magnesium/d for 49d (repletion) in a depletion-repletion experiment. RBC magnesium concentration (P 0.05), magnesium retention (P 0.05) and skeletal muscle magnesium concentration (P 0.05) decreased when dietary magnesium was restricted. Peak oxygen uptake, total and cumulative net oxygen uptake determined by using indirect calorimetry and peak heart rate increased (P 0.05) during standardized submaximal work with restricted compared with adequate dietary magnesium. These findings indicate that dietary magnesium depletion can be induced in otherwise healthy women; it results in increased energy needs and adversely affects cardiovascular function during submaximal work. This may also explain previous observations of increased energy cost during standardized exercise in physically active men and women considered to have reduced magnesium nutriture. J. Nutr. 132: 930 –935, 2002.
Compulsive Buying: What Is Behind The Curtain?

Along with the positive aspect of consumers’ consumption behaviour, negative aspect also needed to consider for obtaining a complete picture of the consumption behaviour. By examining compulsive buying, this study attempts to shed some light on understanding the negativity in consumption. Based on symbolic self-completion theory, this study investigates the relationships among self-esteem, materialism and compulsive buying. Moreover, the mediating role of materialism in the relationship between self-esteem and compulsive buying, and the role of self-esteem as an antecedent as well as a consequence of compulsive buying are also examined. A survey was carried out on 223 undergraduate students. Structural equation modelling was used to analyse the survey data, which revealed that low self-esteem functions as both an antecedent and as a consequence of compulsive buying. Additionally, self-esteem indirectly and materialism directly affect compulsive buying. It is hoped that, this study contributes significantly in the existing body of literature by examining some previously unexplored relationship. Although compulsive buying may help marketers to gain profit, it is a social problem. Therefore, social marketers, policy makers, advertising agencies, government all parties need to take initiative to aware consumers about its ultimate harmful effect. Implications and suggestions for future research are also discussed.
Wireless Information-Theoretic Security

This paper considers the transmission of confidential data over wireless channels. Based on an information-theoretic formulation of the problem, in which two legitimates partners communicate over a quasi-static fading channel and an eavesdropper observes their transmissions through a second independent quasi-static fading channel, the important role of fading is characterized in terms of average secure communication rates and outage probability. Based on the insights from this analysis, a practical secure communication protocol is developed, which uses a four-step procedure to ensure wireless information-theoretic security: (i) common randomness via opportunistic transmission, (ii) message reconciliation, (iii) common key generation via privacy amplification, and (iv) message protection with a secret key. A reconciliation procedure based on multilevel coding and optimized low-density parity-check (LDPC) codes is introduced, which allows to achieve communication rates close to the fundamental security limits in several relevant instances. Finally, a set of metrics for assessing average secure key generation rates is established, and it is shown that the protocol is effective in secure key renewal-even in the presence of imperfect channel state information.
Animal-Assisted Therapy: Benefits and Implications for Professionals in the Field of Rehabilitation

The use of animals for therapeutic purposes has been done for centuries. It wasnrt until the 20thncentury when people began to realize the potential the human-animal interaction had on our overall health. Professionals and organizations began to implement animal-assisted therapy (AAT) and activities, and research began to see the benefits that it could produce. Animal-assisted therapy has shown to provide various populations of individuals with physiological and psychological.
Uric Acid and the Prediction Models of Tumor Lysis Syndrome in AML

We investigated the ability of serum uric acid (SUA) to predict laboratory tumor lysis syndrome (LTLS) and compared it to common laboratory variables, cytogenetic profiles, tumor markers and prediction models in acute myeloid leukemia patients. In this retrospective study patients were risk-stratified for LTLS based on SUA cut-off values and the discrimination ability was compared to current prediction models. The incidences of LTLS were 17.8%, 21% and 62.5% in the low, intermediate and high-risk groups, respectively. SUA was an independent predictor of LTLS (adjusted OR 1.12, CI95% 1.0–1.3, p = 0.048). The discriminatory ability of SUA, per ROC curves, to predict LTLS was superior to LDH, cytogenetic profile, tumor markers and the combined model but not to WBC (AUCWBC 0.679). However, in comparisons between high-risk SUA and high-risk WBC, SUA had superior discriminatory capability than WBC (AUCSUA 0.664 vs. AUCWBC 0.520; p <0.001). SUA also demonstrated better performance than the prediction models (high-risk SUAAUC 0.695, p<0.001). In direct comparison of high-risk groups, SUA again demonstrated superior performance than the prediction models (high-risk SUAAUC 0.668, p = 0.001) in predicting LTLS, approaching that of the combined model (AUC 0.685, p<0.001). In conclusion, SUA alone is comparable and highly predictive for LTLS than other prediction models.
Pengaruh Diversifikasi Bisnis terhadap Risiko Bisnis dan Kinerja Perusahaan Manufaktur di Bursa Efek Indonesia

Penelitian ini bertujuan untuk memberi bukti empiris mengenai pengaruh diversifikasi bisnis terhadap risiko bisnis dan kinerja perusahaan. Diversifikasi bisnis diukur dengan indeks entropy. Risiko bisnis diukur dengan pengungkapan risiko manajemen. Kinerja perusahaan diukur dengan Tobin’s q. Sampel dari penelitian ini adalah 32 perusahaan manufaktur di Bursa Efek Indonesia. Hasil penelitian yang menunjukkan diversifikasi bisnis memiliki pengaruh negatif terhadap risiko bisnis. Ini sesuai dengan hipotesis ke satu yang menjelaskan bahwa diversifikasi memiliki pengaruh negatif terhadap risiko bisnis. Semakin terdiversifikasi suatu perusahaan maka risiko semakin rendah karena kerugian yang dialami akan tertutupi dari keuntungan dari segmen bisnis lain sehingga risiko akan turun. Hasil penelitian menunjukkan hubungan antara diversifikasi bisnis dengan kinerja perusahaan adalah negatif. Ini berarti hipotesis ke dua yang menyatakan diversifikasi bisnis berpengaruh positif terhadap kinerja perusahaan tidak terbukti (ditolak). Penyebab kinerja menurun karena perusahaan yang melakukan diversifikasi terlalu banyak melakukan investasi pada segmen yang memiliki nilai keuntungan rendah. Kata kunci : Diversifikasi bisnis, Kinerja Perusahaan, Tobin’s q, Risiko Bisnis
Toxicity of Single and Mixtures of Antibiotics to Cyanobacteria

The present study was designed to investigate the disappearance of cyanobacterial mat from fish breeding lakes and to evaluate the phytotoxic effects of Penicillin, Ciprofloxacin, and Tylosin as single and as mixtures to cyanobacterial mats. Phytotoxic effects were measured as growth inhibition of cyanobacteria using spectrophotometer at 680 nm at low concentrations of antibiotics. Results showed potential phytotoxicity of the tested antibiotics with EC50 values of Penicillin, Ciprofloxacin and Tylosin of 0.13, 0.71, 5.28 mg/l respectively. Relative toxicity indicated that Penicillin and Ciprofloxacin were more toxic to cyanobacterial mats than Diuron (standard toxic material). EC50 values of binary mixtures are 0.077, 0.103, 0.292 TU, for (Penicillin+Tylosin), (Ciprofloxacin+Tylosin) and (Ciprofloxacin+Penicillin) respectively; whereas EC50 of the tertiary mixture is 0.034 TU. Statistical analysis of the results indicated significant differences between the toxic effects of compounds and their mixtures to cyanobacterial mats. Observation of toxicity of over time indicated that cyanobacterial mats were able to overcome the toxic effects after approximately 72 h of exposure time. It can be concluded that antibiotics exert dangerous toxic effects to cyanobacterial mat, an important organism in the eco-system. These results are considered the first of its kind in Palestine.
Thermodynamic Scaling of the Hydrological Cycle of the Last Glacial Maximum

AbstractIn climate models subject to greenhouse gas–induced warming, vertically integrated water vapor increases at nearly the same rate as its saturation value. Previous studies showed that this increase dominates circulation changes in climate models, so that precipitation minus evaporation (P − E) decreases in the subtropics and increases in the tropics and high latitudes at a rate consistent with a Clausius–Clapeyron scaling. This study examines whether the same thermodynamic scaling describes differences in the hydrological cycle between modern times and the last glacial maximum (LGM), as simulated by a suite of coupled ocean–atmosphere models. In these models, changes in water vapor between modern and LGM climates do scale with temperature according to Clausius–Clapeyron, but this thermodynamic scaling provides a poorer description of the changes in P − E. While the scaling is qualitatively consistent with simulations in the zonal mean, predicting higher P − E in the subtropics and lower P − E in th.
QT dispersion: comparison between diabetic and non-diabetic individuals and correlation with cardiac autonomic neuropathy.

INTRODUCTION The QT interval on the resting electrocardiogram (ECG) expresses the myocardial depolarisation and repolarisation time. Elevated values of QT dispersion (QTd) are associated with cardiovascular mortality in diabetics. Cardiac autonomic neuropathy (CAN) is a common complication of diabetes that is also associated with increased morbidity and mortality. However, there are no data in the literature concerning the relation between CAN and QTd in diabetics. The aim of this study was to investigate: 1) the differences in QTd between diabetics and non-diabetics; 2) the differences in QTd between those with type 1 and type 2 diabetes; 3) the relation between QTd and CAN. METHODS The study population included 184 diabetics (63 type 1, group D1; 121 type 2, group D2) and 100 healthy controls who had similar age and sex distribution to D1 (n=44) and D2 (n=56) subjects. CAN assessment was made using the standard Ewing and Clarke tests. The QT interval was measured on the 12-lead resting ECG. QTd was calculated automatically using special software. RESULTS QTd values did not differ significantly between controls and D1 (p=0.15) or D2 (p=0.27). QTd was significantly greater in D2 than in D1 (p=0.02). There was no significant difference in QTd between those with and without CAN in either group of diabetics. CONCLUSIONS QTd values do not differ between individuals with and without diabetes. Type 2 diabetes is associated with higher QTd values than is type 1 diabetes. CAN does not affect QTd in diabetics.
Psychological Factors as a Prediction of Success in Duodenal Ulcer Surgery*

An attempt was made to relate the outcome of surgery to psychosocial factors in an unselected series of 30 male patients with duodenal ulcer. Though statistically significant differences did not emerge on the psychosocial parameters studied, patients with good surgical results were less likely to give histories of preoperative anxiety or depression or to show evidence of these at interview. They also had lower ratings on Hamilton Rating and Deprivation Scales, and were more likely to have hopeful expectations of operation and positive attitudes towards previous medical treatment. Patients with psychiatric illness or psychological deprivation having surgery for chronic duodenal ulceration, can expect almost as good a surgical result as those without these difficulties. They are unlikely to show increased psychiatric morbidity, postoperatively.
Transcriptomic Analysis of Leaf in Tree Peony Reveals Differentially Expressed Pigments Genes

Tree peony (Paeonia suffruticosa Andrews) is an important traditional flower in China. Besides its beautiful flower, the leaf of tree peony has also good ornamental value owing to its leaf color change in spring. So far, the molecular mechanism of leaf color change in tree peony is unclear. In this study, the pigment level and transcriptome of three different color stages of tree peony leaf were analyzed. The purplish red leaf was rich in anthocyanin, while yellowish green leaf was rich in chlorophyll and carotenoid. Transcriptome analysis revealed that 4302 differentially expressed genes (DEGs) were upregulated, and 4225 were downregulated in the purplish red leaf vs. yellowish green leaf. Among these DEGs, eight genes were predicted to participate in anthocyanin biosynthesis, eight genes were predicted involved in porphyrin and chlorophyll metabolism, and 10 genes were predicted to participate in carotenoid metabolism. In addition, 27 MYBs, 20 bHLHs, 36 WD40 genes were also identified from DEGs. Anthocyanidin synthase (ANS) is the key gene that controls the anthocyanin level in tree peony leaf. Protochlorophyllide oxido-reductase (POR) is the key gene which regulated the chlorophyll content in tree peony leaf.
Elaborate cellulosome architecture of Acetivibrio cellulolyticus revealed by selective screening of cohesin–dockerin interactions

Cellulosic waste represents a significant and underutilized carbon source for the biofuel industry. Owing to the recalcitrance of crystalline cellulose to enzymatic degradation, it is necessary to design economical methods of liberating the fermentable sugars required for bioethanol production. One route towards unlocking the potential of cellulosic waste lies in a highly complex class of molecular machines, the cellulosomes. Secreted mainly by anaerobic bacteria, cellulosomes are structurally diverse, cell surface-bound protein assemblies that can contain dozens of catalytic components. The key feature of the cellulosome is its modularity, facilitated by the ultra-high affinity cohesin–dockerin interaction. Due to the enormous number of cohesin and dockerin modules found in a typical cellulolytic organism, a major bottleneck in understanding the biology of cellulosomics is the purification of each cohesin- and dockerin-containing component, prior to analyses of their interaction. As opposed to previous approaches, the present study utilized proteins contained in unpurified whole-cell extracts. This strategy was made possible due to an experimental design that allowed for the relevant proteins to be “purified” via targeted affinity interactions as a function of the binding assay. The approach thus represents a new strategy, appropriate for future medium- to high-throughput screening of whole genomes, to determine the interactions between cohesins and dockerins. We have selected the cellulosome of Acetivibrio cellulolyticus for this work due to its exceptionally complex cellulosome systems and intriguing diversity of its cellulosomal modular components. Containing 41 cohesins and 143 dockerins, A. cellulolyticus has one of the largest number of potential cohesin–dockerin interactions of any organism, and contains unusual and novel cellulosomal features. We have surveyed a representative library of cohesin and dockerin modules spanning the cellulosome’s total cohesin and dockerin sequence diversity, emphasizing the testing of unusual and previously-unknown protein modules. The screen revealed several novel cell-bound cellulosome architectures, thus expanding on those previously known, as well as soluble cellulose systems that are not bound to the bacterial cell surface. This study sets the stage for screening the entire complement of cellulosomal components from A. cellulolyticus and other organisms with large cellulosome systems. The knowledge gained by such efforts brings us closer to understanding the exceptional catalytic abilities of cellulosomes and will allow the use of novel cellulosomal components in artificial assemblies and in enzyme cocktails for sustainable energy-related research programs.
Minimally cross-entropic conditional density : a generalization of the GARCH model

Svetlozar T. Rachev Chair-Professor, Chair of Statistics, Econometrics and Mathematical Finance, School of Economics and Business Engineering, University of Karlsruhe and KIT, and Department of Statistics and Applied Probability, University of California, Santa Barbara, and Chief-Scientist, FinAnalytica INC Kollegium am Schloss, Bau II, 20.12, R210, Postfach 6980, D-76128, Karlsruhe, Germany Tel. : +49(0721)608 7535 Fax. : +49(0721)608 3811 E-mail: rachev@statistik.uni-karlsruhe.de
Exercise training increases the Ca(2+) sensitivity of tension in rat cardiac myocytes.

The heart is known to respond to a program of chronic exercise in ways that enhance cardiac function. However, the cellular mechanisms involved in training-induced improvements in the contractile function of the myocardium are not known. In this study we tested the hypothesis that increased contractility of the myocardium associated with exercise training is due, in part, to increases in the Ca(2+) sensitivity of steady-state tension. Female Sprague-Dawley rats were randomly divided into sedentary control (C) and exercise-trained (T) groups. The T rats underwent 11 wk of progressive treadmill exercise (1 h/day, 5 days/wk, 26 m/min, 20% grade). Evidence of training effect included a 5.9% increase in heart mass, increases in heart weight-to-body weight ratio, and a 60% increase in skeletal muscle citrate synthase activity in T rats compared with C rats. After the training program, cardiac myocytes were isolated from T and C hearts. Myocytes were chemically skinned (i.e., the sarcolemma was removed) and attached to a force transducer, and steady-state tension was determined in solutions of various Ca(2+) concentrations ([Ca(2+)]). Myocytes isolated from the hearts of T rats showed a significantly (P < 0.01) increased sensitivity of tension to [Ca(2+)]. The [Ca(2+)] giving 50% of maximal tension (pCa(50)) was 5.90 +/- 0.033 and 5.82 +/- 0.023 (SD) in T and C myocytes, respectively (n = 70 myocytes/group). This result suggests that exercise training affects the myofibrillar proteins, such that Ca(2+) sensitivity is increased, and that this may be the mechanism that underlies, at least in part, the effect of training to increase myocardial contractility.