Miracle-dz/UniFAR-FTUs huggingface dataset:
Integrated care: a comprehensive bibliometric analysis and literature review

Introduction Integrated care could not only fix up fragmented health care but also improve the continuity of care and the quality of life. Despite the volume and variety of publications, little is known about how ‘integrated care’ has developed. There is a need for a systematic bibliometric analysis on studying the important features of the integrated care literature. Aim To investigate the growth pattern, core journals and jurisdictions and identify the key research domains of integrated care. Methods We searched Medline/PubMed using the search strategy ‘(delivery of health care, integrated [MeSH Terms]) OR integrated care [Title/Abstract]’ without time and language limits. Second, we extracted the publishing year, journals, jurisdictions and keywords of the retrieved articles. Finally, descriptive statistical analysis by the Bibliographic Item Co-occurrence Matrix Builder and hierarchical clustering by SPSS were used. Results As many as 9090 articles were retrieved. Results included: (1) the cumulative numbers of the publications on integrated care rose perpendicularly after 1993; (2) all documents were recorded by 1646 kinds of journals. There were 28 core journals; (3) the USA is the predominant publishing country; and (4) there are six key domains including: the definition/models of integrated care, interdisciplinary patient care team, disease management for chronically ill patients, types of health care organizations and policy, information system integration and legislation/jurisprudence. Discussion and conclusion Integrated care literature has been most evident in developed countries. International Journal of Integrated Care is highly recommended in this research area. The bibliometric analysis and identification of publication hotspots provides researchers and practitioners with core target journals, as well as an overview of the field for further research in integrated care.
The HandSolo: A Hand Drum Controller for Natural Rhythm Entry and Production

The majority of electronic percussion controllers on the market today are based on location-oriented striking techniques, resulting in a“finger drumming”interaction paradigm, that is both fundamentally eclectic as well as imposingly “controllerist”. The few controllers that allow hand-drumming techniques also invariably conform to region-based triggering design, or, in trade-off for expressivity, end up excluding hardware connectivity options that are vital to the context of the modern electronic rhythm producer. The HandSolo is a timbre-based drum controller that allows the use of natural, hand-drumming strokes, whilst offering the same end-goal functionality that percussion controller users have come to expect over the past decade.
NTCIR-10 CrossLink-2 Task: A Link Mining Strategy

At NTCIR-10 we participated in the cross-lingual link discovery (CrossLink-2) task. In this paper we describe our systems for discovering cross-lingual links between the Chinese, Japanese, and Korean (CJK) Wikipedia and the English Wikipedia. The evaluation results show that our implementation of the cross-lingual linking method achieved promising results.
A Comprehensive Review of Punica granatum (Pomegranate) Properties in Toxicological, Pharmacological, Cellular and Molecular Biology Researches

Punica granatum (Pg), commonly known as pomegranate (Pg), is a member of the monogeneric family, Punicaceae, and is mainly found in Iran which is considered to be its primary centre of origin. Pg and its chemical components possess various pharmacological and toxicological properties including antioxidant, anti-inflammatory (by inhibiting pro-inflammatory cytokines), anti-cancer and anti-angiogenesis activities. They also show inhibitory effects on invasion/motility, cell cycle, apoptosis, and vital enzymes such as cyclooxygenase (COX), lipooxygenase (LOX), cytochrome P450 (CYP450), phospholipase A2 (PLA2), ornithine decarboxylase (ODC), carbonic anhydrase (CA), 17beta-hydroxysteroid dehydrogenase (17β-HSDs) and serine protease (SP). Furthermore, they can stimulate cell differentiation and possess anti-mutagenic effects. Pg can also interfere with several signaling pathways including PI3K/AKT, mTOR, PI3K, Bcl-X, Bax, Bad, MAPK, ERK1/2, P38, JNK, and caspase. However, the exact mechanisms for its pharmacological and toxicological properties remain to be unclear and need further evaluation. These properties strongly suggest a wide range use of Pg for clinical applications. This review will discuss the areas for which Pg has shown therapeutic properties in different mechanisms.
Hyperpolarization-Activated Current Induces Period-Doubling Cascades and Chaos in a Cold Thermoreceptor Model

In this article, we describe and analyze the chaotic behavior of a conductance-based neuronal bursting model. This is a model with a reduced number of variables, yet it retains biophysical plausibility. Inspired by the activity of cold thermoreceptors, the model contains a persistent Sodium current, a Calcium-activated Potassium current and a hyperpolarization-activated current (Ih) that drive a slow subthreshold oscillation. Driven by this oscillation, a fast subsystem (fast Sodium and Potassium currents) fires action potentials in a periodic fashion. Depending on the parameters, this model can generate a variety of firing patterns that includes bursting, regular tonic and polymodal firing. Here we show that the transitions between different firing patterns are often accompanied by a range of chaotic firing, as suggested by an irregular, non-periodic firing pattern. To confirm this, we measure the maximum Lyapunov exponent of the voltage trajectories, and the Lyapunov exponent and Lempel-Ziv's complexity of the ISI time series. The four-variable slow system (without spiking) also generates chaotic behavior, and bifurcation analysis shows that this is often originated by period doubling cascades. Either with or without spikes, chaos is no longer generated when the Ih is removed from the system. As the model is biologically plausible with biophysically meaningful parameters, we propose it as a useful tool to understand chaotic dynamics in neurons.
Necessary and Sufficient LMI Conditions for Stability and Performance Analysis of 2-D Mixed Continuous-Discrete-Time Systems

This paper proposes necessary and sufficient conditions for stability and performance analysis of 2-D mixed continuous-discrete-time systems that can be checked with convex optimization, in particular linear matrix inequalities (LMIs). Specifically, the first contribution of the paper is a condition for exponential stability based on the introduction of a complex Lyapunov function depending polynomially on a parameter and on the use of the Gram matrix method. It is shown that this condition is sufficient for any chosen degree of the complex Lyapunov function, and necessary for an a priori known degree. The second contribution is a non-Lyapunov condition for exponential stability based on eigenvalue products. This condition is necessary and sufficient, and has the advantage of requiring a significantly smaller computational burden for achieving necessity. Lastly, the third contribution is to show how upper bounds on the H∞ norm of 2-D mixed continuous-discrete-time systems can be obtained through a semidefinite program based on complex Lyapunov functions. A necessary and sufficient condition is provided for establishing the tightness of the found upper bounds.
The PPVT-R as a measure of psycholinguistic functioning: a caution.

The present investigation was undertaken to evaluate the use of the PPVT-R as a measure of psycholinguistic functioning. The sample included 75 school-aged children referred for evaluation. The mean PPVT-R standard score (94.59, SD = 15.85) was not significantly different (p less than .01) than the WISC-R Full Scale IQ (95.36, SD = 16.29), Verbal IQ (94.36, SD = 16.17), or Performance IQ (97.75, SD = 15.61), or the mean ITPA PLQ. The PPVT-R correlated positively and significantly with the WISC-R Full Scale IQ (.77), Verbal IQ (.71) and Performance IQ (.74) and the WISC-R subtests, with coefficients that ranged from . 42 (object assembly) to . 69 (vocabulary). In addition, the PPVT-R correlated positively and significantly with the ITPA Psycho-Linguistic Quotient (PLQ) (.72) and the ITPA) subtests, with coefficients that ranged from . 38 (auditory sequential memory) to . 72 (grammatic closure). Regression analyses determined that the ITPA PLQ and the PPVT-R standard score were not predictive of one another. The data are interpreted to suggest that the PPVT-R is not more appropriately used as a measure of receptive language ability than as a screen for intellectual functioning.
IBEX: an open infrastructure software platform to facilitate collaborative work in radiomics.

PURPOSE Radiomics, which is the high-throughput extraction and analysis of quantitative image features, has been shown to have considerable potential to quantify the tumor phenotype. However, at present, a lack of software infrastructure has impeded the development of radiomics and its applications. Therefore, the authors developed the imaging biomarker explorer (IBEX), an open infrastructure software platform that flexibly supports common radiomics workflow tasks such as multimodality image data import and review, development of feature extraction algorithms, model validation, and consistent data sharing among multiple institutions. METHODS The IBEX software package was developed using the MATLAB and c/c++ programming languages. The software architecture deploys the modern model-view-controller, unit testing, and function handle programming concepts to isolate each quantitative imaging analysis task, to validate if their relevant data and algorithms are fit for use, and to plug in new modules. On one hand, IBEX is self-contained and ready to use: it has implemented common data importers, common image filters, and common feature extraction algorithms. On the other hand, IBEX provides an integrated development environment on top of MATLAB and c/c++, so users are not limited to its built-in functions. In the IBEX developer studio, users can plug in, debug, and test new algorithms, extending IBEX's functionality. IBEX also supports quality assurance for data and feature algorithms: image data, regions of interest, and feature algorithm-related data can be reviewed, validated, and/or modified. More importantly, two key elements in collaborative workflows, the consistency of data sharing and the reproducibility of calculation result, are embedded in the IBEX workflow: image data, feature algorithms, and model validation including newly developed ones from different users can be easily and consistently shared so that results can be more easily reproduced between institutions. RESULTS Researchers with a variety of technical skill levels, including radiation oncologists, physicists, and computer scientists, have found the IBEX software to be intuitive, powerful, and easy to use. IBEX can be run at any computer with the windows operating system and 1GB RAM. The authors fully validated the implementation of all importers, preprocessing algorithms, and feature extraction algorithms. Windows version 1.0 beta of stand-alone IBEX and IBEX's source code can be downloaded. CONCLUSIONS The authors successfully implemented IBEX, an open infrastructure software platform that streamlines common radiomics workflow tasks. Its transparency, flexibility, and portability can greatly accelerate the pace of radiomics research and pave the way toward successful clinical translation.
Evaluation of New Jersey's Sex Offender Treatment Program at the Adult Diagnostic and Treatment Center: Preliminary Results

This study examined 10-year sexual and non-sexual offense recidivism for sex offenders released from New Jersey's general prison system and from the Adult Diagnostic and Treatment Center (ADTC), New Jersey's correctional facility and treatment center for repetitive-compulsive sexual offenders. The study found that sexual offenders released from the ADTC had significantly lower rates of committing both non-sexual offenses and any offense, compared with the general prison population of sex offenders. For both groups, the 10-year sexual offense reconviction rates were relatively low, 8.6% for the ADTC offenders and 12.7% for the general prison sexual offenders, while reoffense rates for non-sexual offenses were 25.8% and 44.1% for ADTC and general prison sex offenders, respectively.
LXR agonists and ABCG1-dependent cholesterol efflux in MCF-7 breast cancer cells: relation to proliferation and apoptosis.

BACKGROUND Liver X receptor (LXR) plays a key role in reverse cholesterol transport by inducing the expression of the ATP-binding cassette (ABC) transporters, implicated in cholesterol efflux. Recent data showed that LXR agonists inhibit the proliferation of multiple types of human cancer cells. However, whether these effects are related to cholesterol efflux has not yet been elucidated. MATERIALS AND METHODS Effects of two LXR agonists (TO901317 and 22(R)-hydroxycholesterol [22(R)-HC]) on proliferation, apoptosis and cholesterol efflux were examined in MCF-7 breast cancer cells. RESULTS Treatment with LXR agonists (TO901317 at 20 μM and 22(R)-HC at 2 μg/ml) inhibited proliferation and induced apoptosis of MCF-7 cells. Furthermore, LXR activation resulted in an increase in gene and protein levels of ABCG1 transporters and in cholesterol efflux to isolated high-density lipoprotein (HDL), without affecting the ABCA1/APOA-I mediated efflux. Under these conditions, a remarkable reduction of intracellular and membrane-associated cholesterol levels was observed. CONCLUSION LXR activation in MCF-7 cells could deprive cells of cholesterol, required for their growth, by stimulating its efflux, resulting in the inhibition of cell proliferation and in stimulation of apoptosis.
Patient baseline interpersonal problems as moderators of outcome in two psychotherapies for bulimia nervosa

Abstract Objective: We tested an aptitude by treatment interaction; namely, whether patients’ baseline interpersonal problems moderated the comparative efficacy of cognitive-behavioral therapy (CBT) vs. interpersonal psychotherapy (IPT) for bulimia nervosa (BN). Method: Data derived from a randomized-controlled trial. Patients reported on their interpersonal problems at baseline; purge frequency at baseline, midtreatment, and posttreatment; and global eating disorder severity at baseline and posttreatment. We estimated the rate of change in purge frequency across therapy, and the likelihood of attaining clinically meaningful improvement (recovery) in global eating disorder severity by posttreatment. We then tested the interpersonal problem by treatment interactions as predictors of both outcomes. Results: Patients with more baseline overly communal/friendly problems showed steeper reduction in likelihood of purging when treated with CBT vs. IPT. Patients with more problems of being under communal/cold had similar reductions in likelihood of purging across both treatments. Patients with more baseline problems of being overly agentic were more likely to recover when treated with IPT vs. CBT, whereas patients with more problems of being under agentic were more likely to recover when treated with CBT vs. IPT. Conclusions: Interpersonal problems related to communion and agency may inform treatment fit among two empirically supported therapies for BN.
On the Misdiagnosis of Surface Temperature Feedbacks from Variations in Earth's Radiant Energy Balance

The sensitivity of the climate system to an imposed radiative imbalance remains the largest source of uncertainty in projections of future anthropogenic climate change. Here we present further evidence that this uncertainty from an observational perspective is largely due to the masking of the radiative feedback signal by internal radiative forcing, probably due to natural cloud variations. That these internal radiative forcings exist and likely corrupt feedback diagnosis is demonstrated with lag regression analysis of satellite and coupled climate model data, interpreted with a simple forcing-feedback model. While the satellite-based metrics for the period 2000–2010 depart substantially in the direction of lower climate sensitivity from those similarly computed from coupled climate models, we find that, with traditional methods, it is not possible to accurately quantify this discrepancy in terms of the feedbacks which determine climate sensitivity. It is concluded that atmospheric feedback diagnosis of the climate system remains an unsolved problem, due primarily to the inability to distinguish between radiative forcing and radiative feedback in satellite radiative budget observations.
A Cognitive Ecological Model of Women's Response to Male Sexual Coercion in Dating.

We offer a theoretical model that consolidates background, environmental, and intrapersonal variables related to women's experience of sexual coercion in dating into a coherent ecological framework and present for the first time a cognitive analysis of the processes women use to formulate responses to sexual coercion. An underlying premise for this model is that a woman's coping response to sexual coercion by an acquaintance is mediated through cognitive processing of background and situational influences. Because women encounter this form of sexual coercion in the context of relationships and situations that they presume will follow normative expectations (e.g., about making friends, socializing and dating), it is essential to consider normative processes of learning, cognitive mediation, and coping guiding their efforts to interpret and respond to this form of personal threat. Although acts of coercion unquestionably remain the responsibility of the perpetrator, a more complete understanding of the multilevel factors shaping women's perception of and response to threats can strengthen future inquiry and prevention efforts.
Email answering assistance by semi-supervised text classification

Many individuals, organizations, and companies have to answer large amounts of emails. Often, many of these emails contain variations of relatively few frequently asked questions. We address the problem of predicting which of several frequently used answers a user will choose to respond to an email. We map the problem to a semi-supervised text classification problem. In a case study with emails that have been sent to a corporate customer service department, we investigate the ability of the naive Bayesian and support vector classifier to identify the appropriate answers to emails. We study how effectively the transductive Support Vector Machine and the co-training algorithm utilize unlabeled data and investigate why co-training is only beneficial when very few labeled data are available. In addition, we describe a practical assistance system.
A semi-preemptive garbage collector for solid state drives

NAND flash memory is a preferred storage media for various platforms ranging from embedded systems to enterprise-scale systems. Flash devices do not have any mechanical moving parts and provide low-latency access. They also require less power compared to rotating media. Unlike hard disks, flash devices use out-of-update operations and they require a garbage collection (GC) process to reclaim invalid pages to create free blocks. This GC process is a major cause of performance degradation when running concurrently with other I/O operations as internal bandwidth is consumed to reclaim these invalid pages. The invocation of the GC process is generally governed by a low watermark on free blocks and other internal device metrics that different workloads meet at different intervals. This results in I/O performance that is highly dependent on workload characteristics. In this paper, we examine the GC process and propose a semi-preemptive GC scheme that can preempt on-going GC processing and service pending I/O requests in the queue. Moreover, we further enhance flash performance by pipelining internal GC operations and merge them with pending I/O requests whenever possible. Our experimental evaluation of this semi-preemptive GC sheme with realistic workloads demonstrate both improved performance and reduced performance variability. Write-dominant workloads show up to a 66.56% improvement in average response time with a 83.30% reduced variance in response time compared to the non-preemptive GC scheme.
The Effectiveness of Robot Pronunciation Training for Second Language Acquisition by Children: Segmental and Suprasegmental Feature Analysis Approaches.

This study introduced the effectiveness of robot pronunciation training for Korean children's second language acquisition by investigating whether there would be significant differences between beforeand after pronunciation training by robot, iRobiQ, as an instructional assistant about the Koreans' most problematic target segmental features, consonants and vowels, and suprasegmental features, intonation, to 18 Korean EFL students at Songnisan Sujung Elementary School. This current study used a mixed research design, quantitative and qualitative, for data collection and analysis. The overall findings from all 8 weeks' treatments yielded statistically significant results as overall learning outcomes after all treatments. While training target pronunciations with a robot, iRobiQ, most of the students showed their positive perceptions about robot iRobiQ as a learning assistant and familiar tool, together with their improved self-confidence and comfort levels in terms of showing more frequent contact with a robot, iRobiQ, and their positive views on robot as an educational tool. The overall results suggest a new paradigm about our knowledge and implications in teaching and learning English pronunciation for Korean EFL elementary school students in second language acquisition.
Molecular characterization of Escherichia coli FtsE and FtsX

The genes ftsE and ftsX are organized in one operon together with ftsY. FtsY codes for the receptor of the signal recognition particle (SRP) that functions in targeting a subset of inner membrane proteins. We have found no indications for a structural relationship between FtsE/X and FtsY. Evidence is presented that FtsE and FtsX form a complex in the inner membrane that bears the characteristics of an ATP‐binding cassette (ABC)‐type transporter. FtsE is a hydrophilic nucleotide‐binding protein that has a tendency to dimerize and associates with the inner membrane through an interaction with the integral membrane protein FtsX. An FtsE null mutant showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport.
Numerical modeling of non-Newtonian viscoplastic flows: Part II. Viscoplastic fluids and general tridimensional topographies

A new reduced model for the shallow tridimensional viscoplastic fluid flowing on a general topography is presented in this paper. A second order and implicit time-dependent numerical algorithm is proposed to solve this problem, providing an auto-adaptive mesh feature for caching accurately the evolution of front position and predict accurately the long-time behavior and the arrested state of the model. This approach was tested on two flows experiments and compared to experimental measurements. The first study shows the efficiency of this approach when the shallow flow conditions are fully satisfied while the second one points out the limitations of the reduced model when these conditions are not satisfied.