Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of performance indicators on the time the first goal is scored in football matches

Scoring the first goal in football could be crucial for winning a match. The aim of this study was to identify the performance indicators that influence the time the first goal is scored in high-level football matches. A total of 240 matches of the Portuguese Premier League played in 2009/10 season were analysed. The difference between the total number of goals scored and conceded during the competition up until the match considered, total ball possession time, shots on goal, set plays, disciplinary sanctions and substitutions were selected as predictor variables for the time the first goal is scored and loaded on a Cox regression model with time-dependent covariates. A greater goal difference (p < 0.05) and a larger number of shots on goal (p < 0.01) had a positive significant influence on the time the first goal was scored in the match by home teams; at the same time disciplinary sanctions (p < 0.01) and substitutions (p < 0.01) had a negative significant effect on the time of the first goal.
Molecular Imaging Reveals a Role for AKT in Resistance to Cisplatin for Ovarian Endometrioid Adenocarcinoma

Purpose: Ovarian cancer is the fifth leading cause of cancer-related deaths among American women. Platinum-based chemotherapy, such as cisplatin, represents the standard-of-care for ovarian cancer. However, toxicity and acquired resistance to cisplatin have proven challenging in the treatment of patients with ovarian cancer. Experimental Design: Using a genetically engineered mouse model of ovarian endometrioid adenocarcinoma (OEA) in combination with molecular-imaging technologies, we studied the activation of the AKT serine/threonine kinase in response to long-term cisplatin therapy. Results: Treatment of cells in culture and tumor-bearing animals with cisplatin resulted in activation of AKT, a key mediator of cell survival. On the basis of these results, we investigated the therapeutic use of AKT inhibition in combination with cisplatin, which resulted in enhanced and prolonged induction of apoptosis and in significantly improved tumor control as compared with either agent alone. Conclusion: These results provide an impetus for clinical trials using combination therapy. To facilitate these trials, we also show the use of diffusion-weighted MRI as an imaging biomarker for evaluation of therapeutic efficacy in OEA. Clin Cancer Res; 19(1); 158–69. ©2012 AACR.
Human Influence on the Spatial Structure of Threatened Pacific Salmon Metapopulations

Abstract: To remain viable, populations must be resilient to both natural and human‐caused environmental changes. We evaluated anthropogenic effects on spatial connections among populations of Chinook salmon (Oncorhynchus tshawytscha) and steelhead (O. mykiss) (designated as threatened under the U.S. Endangered Species Act) in the lower Columbia and Willamette rivers. For several anthropogenic‐effects scenarios, we used graph theory to characterize the spatial relation among populations. We plotted variance in population size against connectivity among populations. In our scenarios, reduced habitat quality decreased the size of populations and hydropower dams on rivers led to the extirpation of several populations, both of which decreased connectivity. Operation of fish hatcheries increased connectivity among populations and led to patchy or panmictic populations. On the basis of our results, we believe recolonization of the upper Cowlitz River by fall and spring Chinook and winter steelhead would best restore metapopulation structure to near‐historical conditions. Extant populations that would best conserve connectivity would be those inhabiting the Molalla (spring Chinook), lower Cowlitz, or Clackamas (fall Chinook) rivers and the south Santiam (winter steelhead) and north fork Lewis rivers (summer steelhead). Populations in these rivers were putative sources; however, they were not always the most abundant or centrally located populations. This result would not have been obvious if we had not considered relations among populations in a metapopulation context. Our results suggest that dispersal rate strongly controls interactions among the populations that comprise salmon metapopulations. Thus, monitoring efforts could lead to understanding of the true rates at which wild and hatchery fish disperse. Our application of graph theory allowed us to visualize how metapopulation structure might respond to human activity. The method could be easily extended to evaluations of anthropogenic effects on other stream‐dwelling populations and communities and could help prioritize among competing conservation measures.
Towards Designing Creative Artificial Systems

Can artificial systems be creative? Can they be designed to be creative on their own? And what are the requirements of such creative artificial systems? To be able to support humans who are expected to deliver creative solutions, or to automate part of their tasks, this paper presents a proposal for creativity requirements that provide a basis for designing creative artificial systems.
The symbolic violence of setting: A Bourdieusian analysis of mixed methods data on secondary students’ views about setting

‘Setting’ is a widespread practice in the UK, despite little evidence of its efficacy and substantial evidence of its detrimental impact on those allocated to the lowest sets. Taking a Bourdieusian approach, we propose that setting can be understood as a practice through which the social and cultural reproduction of dominant power relations is enacted within schools. Drawing on survey data from 12,178 Year 7 (age 11/12) students and discussion groups and individual interviews with 33 students, conducted as part of a wider project on secondary school grouping practices, we examine the views of students who experience setting, exploring the extent to which the legitimacy of the practice is accepted or challenged, focusing on students’ negative views about setting. Analyses show that privileged students (White, middle class) were most likely to be in top sets whereas working‐class and Black students were more likely to be in bottom sets. Students in the lowest sets (and boys, Black students and those in receipt of free school meals) were the most likely to express negative views of setting and to question the legitimacy and ‘fairness’ of setting as a practice, whereas top‐set students defended the legitimacy of setting and set allocations as ‘natural’ and ‘deserved’. This paper argues that setting is incompatible with social justice approaches to education and calls for the foregrounding of the views of those who are disadvantaged by the practice as a tool for challenging the doxa of setting.
Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence

Using a valid chronic mild stress (CMS) model of depression, we found that adolescent (postnatal days [PND] 28–41) CMS induced transient alterations in anhedonia that did not persist into adulthood after a 3-week recovery period. Previously stressed adult rats exhibited more immobility/despair behaviors in the forced swimming test and a greater number of trials to reach criterion in the set-shifting task, suggesting the impaired ability to cope with stressors and the cognitive flexibility that allows adaptation to dynamic environments during adulthood. In addition, adult rat exposure to adolescent CMS had a relatively inhibited activation in ERK signaling and downstream protein expression of phosphorylated cAMP-response element-binding protein (CREB) and brain-derived neurotrophic factor (BDNF) in the medial prefrontal cortex. Further correlation analysis demonstrated that immobility and set-shifting performance were positively correlated with the inhibition of ERK signaling. These results indicated adolescent CMS can be used as an effective stressor to model an increased predisposition to adult depression.
Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA network

A recent study by Persico et al. [2001: Mol Psychiatry 6:150–159] suggests alleles of a CGG polymorphism, just 5′ of the reelin gene (RELN) initiator codon, confer liability for autism, especially alleles bearing 11 or more CGG repeats (long alleles). The association is consistent across both a case‐control and family‐based sample. We attempted to replicate their finding using a larger, independent family‐based sample from the NIH Collaborative Programs of Excellence in Autism (CPEA) Network. In our data, allele transmissions to individuals with autism versus unaffected individuals are unbiased, both when alleles are classified by repeat length and when they are classified into long/short categories. Because of the apparent linkage of autism to chromosome 7q, particularly related to the development of language, we also evaluate the relationship between Reelin alleles and the age at which autism subjects use their first word or first phrase. Neither is significantly associated with Reelin alleles. Our results are not consistent with a major role for Reelin alleles in liability to autism. Published 2004 Wiley‐Liss, Inc.
The Short-Run Macroeconomic Impact of Foreign Aid to Small States: An Agnostic Time Series Analysis

Abstract This paper investigates the short-run macroeconomic impact of aid in small developing countries (SDCs) by using a vector auto regression (VAR) model to study the impact of aid on net import (absorption) and domestic demand (spending). We focus on average country effects within two country sub-groups, and find substantial differences between ‘aid-dependent’ SDCs and other SDCs that are more dependent on natural resources, tourism or financial services. In aid-dependent SDCs, aid absorption more or less equals spending, although only half of the aid flow is absorbed and spent. In the non-aid-dependent group, aid does not seem to be absorbed or spent in any systematic fashion.
Memristor Crossbar-Based Pattern Recognition Circuit Using Perceptron Learning Rule

This paper presents a memristor crossbar-basedpattern recognition circuit using perceptron learning rule. Theproposed circuit includes a memristor crossbar based trainingcircuit (TC)-module referred as 'synaptic network' and an operationalamplifier (Op-Amp) based neuron circuit. The TC-moduleis utilized to adjust synaptic weights according to applied inputpatterns such as alphabets (A-Z) and numeric (0-9) numbersusing perceptron learning rule. It has 16-input for TC-modulethat are interconnected to 9-output neurons through memristors. Both patterns alphabets (A-Z) and numeric (0-9) numbers aredisplayed input form of 4x4 pixels and output form of 3x3 pixels. Both patterns are recognized by single proposed circuit. Forbetter understanding, only pattern 'A' has been demonstratedin detail.
An Attempt to Recognize Handwritten Tamil Character Using Kohonen SOM

-------------------------------------------------------------------------ABSTRACT ------------------------------------------------------------- This paper presents a new approach of Kohonen neural network based Self Organizing Map (SOM) algorithm for Tamil Character Recognition. Which provides much higher performance than the traditional neural network. Approaches: Step 1: It describes how a system is used to recognize a hand written Tamil characters using a classification approach. The aim of the pre-classification is to reduce the number of possible candidates of unknown character, to a subset of the total character set. This is otherwise known as cluster, so the algorithm will try to group similar characters together. Step 2: Members of pre-classified group are further analyzed using a statistical classifier for final recognition. A recognition rate of around 79.9% was achieved for the first choice and more than 98.5% for the top three choices. The result shows that the proposed Kohonen SOM algorithm yields promising output and feasible with other existing techniques.
Online adaptation of the IEEE 802.15.4 parameters for wireless networked control systems

Abstract The IEEE 802.15. 4 has been studied for its possible use to support networked control systems. A careful management of the network resources allows the enhancement of the quality of control (QoC) of the controlled system. This can be achieved by a co-design approach to manage the interaction between the WNCS and the wireless network in order to online adapt the QoC. This approach allows control loops to have access to the communication medium according to the state of the controlled system meanwhile attempting to optimize the overall control performance. When the QoC of the controlled system is not sufficient, the quality of service of the network is adapted online. This adaptation is realized by modifying the macMinBE parameter of the MAC protocol of the IEEE 802.15. 4. Moreover, an implementation way of this scheme using the IEEE 802.15. 4 protocol is presented. Simulation results show that this approach improves the control performance.
Attitudes toward menopause in HIV-infected and at-risk women

Objective To study attitudes toward menopause in women with or at risk of human immunodeficiency virus (HIV) aged 35 to 60 in New York City, NY, USA. Design Data were obtained at the baseline interview in a cohort study of menopause. Of 502 participating women, 92 were postmenopausal and 162 were perimenopausal. Results Overall, 37.5% of women had a relatively favorable attitude toward menopause. African Americans had a 72% greater odds of a positive attitude (OR = 1.72, 95% CI 1.16–2.57) than all other groups after adjusting for covariates. Hispanic women had the least favorable view of menopause. Experience of >3 menopausal symptoms and negative life events—being a witness to a murder, and the death of a child—were significantly associated with negative attitudes towards menopause (OR = 0.62, 95% CI 0.42–0.93 and OR = 0.64, 95% CI 0.43–0.93, respectively). Depressive symptoms, street drug use, and having a domestic partner, which is significant in single variable analyses, did not remain independent predictors in multivariate results. HIV status, menopause status, and age at interview were not associated with menopause attitudes. Conclusions HIV-infected, drug-using, low-income women showed generally unfavorable attitudes towards menopause. High stress life events coupled with a high prevalence of depressive symptoms indicate this population has special needs marked by the menopause transition into older age.
Gendered Representation and Critical Mass: Women’s Legislative Representation and Social Spending in 22 OECD Countries

To better understand the dynamics of representation of women’s interests such as public expenditure on healthcare, daycare, and education, this study examines statistical evidence for the notion of critical mass. To do so, this study uses the Comparative Welfare States Data Set and the piecewise regression method to produce two linear models that best fit to the data for different ranges of the share of seats in parliament held by women. The analysis fails to find consistent support for a threshold below which women legislators have little-to-no impact upon policy outcomes. By adjudicating seven hypothetical thresholds, the analysis also shows that when there is a critical mass effect, the 10 percent level is more a consequential threshold than 15, 20, or 30 percent levels. Findings suggest that we reject the idea of a critical threshold for women’s legislative representation. However, the relationship between the representation and social spending is robust with or without presumed critical mass.
Impact of a High-Fat or High-Fiber Diet on Intestinal Microbiota and Metabolic Markers in a Pig Model

To further elaborate interactions between nutrition, gut microbiota and host health, an animal model to simulate changes in microbial composition and activity due to dietary changes similar to those in humans is needed. Therefore, the impact of two different diets on cecal and colonic microbial gene copies and metabolic activity, organ development and biochemical parameters in blood serum was investigated using a pig model. Four pigs were either fed a low-fat/high-fiber (LF), or a high-fat/low-fiber (HF) diet for seven weeks, with both diets being isocaloric. A hypotrophic effect of the HF diet on digestive organs could be observed compared to the LF diet (p < 0.05). Higher gene copy numbers of Bacteroides (p < 0.05) and Enterobacteriaceae (p < 0.001) were present in intestinal contents of HF pigs, bifidobacteria were more abundant in LF pigs (p < 0.05). Concentrations of acetate and butyrate were higher in LF pigs (p < 0.05). Glucose was higher in HF pigs, while glutamic pyruvic transaminase (GPT) showed higher concentrations upon feeding the LF diet (p < 0.001). However, C-reactive protein (CRP) decreased with time in LF pigs (p < 0.05). In part, these findings correspond to those in humans, and are in support of the concept of using the pig as human model.
Arbitrage Opportunities in Arbitrage-Free Models of Bond Pricing

Mathematical models of bond pricing are used by both academics and Wall Street practitioners, with practitioners introducing time-dependent parameters to fit arbitrage-free models to selected asset prices. We show, in a simple one-factor setting, that the ability of such models to reproduce a subset of security prices need not extend to state-contingent claims more generally. The popular Black-Derman-Toy model, for example, overprices call options on long bonds relative to those on short bonds when interest rates exhibit mean reversion. We argue, more generally, that the additional parameters of arbitrage-free models should be complemented by close attention to fundamentals, which might include mean reversion, multiple factors, stochastic volatility, and/or non-normal interest rate distributions.
Max - A Multimodal Assistant in Virtual Reality Construction

In the Collaborative Research Center SFB 360 ``Situated Artificial Communicators'' the anthropomorphic agent Max is under development. Max inhabits a CAVE-like Virtual Reality environment where he is visualized in human size. Engaged in cooperative construction tasks, the human user meets a multimodal communication partner that employs synthetic speech, gaze, facial expression, and gesture. Combining deliberative and reactive conversational behaviors with the capability to initiate assembly actions, the agent guides the user through interactive construction procedures. This paper describes the overall architecture of Max with a focus on dialog and interaction management and the generation of synchronized multimodal utterances.
Circulating Tumor Cells and EpCAM Expression in Neuroendocrine Tumors

Purpose: Neuroendocrine tumors (NET) are heterogeneous tumors with widely variable survival. It is unknown whether they express EpCAM (epithelial cell adhesion molecule) and thus whether NET circulating tumor cells (CTC) are detectable. We systematically investigated EpCAM expression and CTC detection in patients with metastatic NETs and evaluated the potential of CTCs to predict radiological progression. Experimental Design: EpCAM protein expression was evaluated in 74 samples of formalin-fixed, paraffin-embedded NET tissue by immunohistochemistry. Seventy-nine patients with metastatic NETs (42 midgut, 5 unknown primary, 19 pancreatic, 13 bronchopulmonary) had blood samples drawn for CTC isolation and enumeration utilizing the CellSearch platform. Patients were classified as having progressive or nonprogressive disease on the basis of serial imaging. Results: Strong homogeneous, membranous EpCAM expression was observed in all ileal (n = 26) and pancreatic NETs (n = 16), whereas variable EpCAM expression was observed in bronchopulmonary NETs (n = 13). Forty-three percent of midgut and 21% of pancreatic NETs had CTCs detected with a range of 0–62 and 0–11, respectively. The absence of CTCs was strongly associated with stable disease (P < 0.001). There was a moderate correlation between CTC levels and urinary 5-hydroxyindole acetic acid (r = 0.5, P = 0.007) and between CTC levels and burden of liver metastases (B = 8.91, P < 0.001). There was no or low correlation between CTC levels and Ki-67 (r = 0.08, P = 0.59) and serum chromogranin A (r = 0.246, P = 0.03). Conclusions: This is the first systematic analysis showing EpCAM expression and CTC detection in NETs. CTCs seem to be associated with progressive disease and may provide useful prognostic information given the variable survival rates in these tumors. Clin Cancer Res; 17(2); 337–45. ©2011 AACR.
Neural Mechanisms of Attentional Reorienting in Three-Dimensional Space

How the human brain reconstructs the three-dimensional (3D) world from two-dimensional (2D) retinal images has received a great deal of interest as has how we shift attention in 2D space. In contrast, it remains poorly understood how visuospatial attention is shifted in depth. In this fMRI study, by constructing a virtual 3D environment in the MR scanner and by presenting targets either close to or far from the participants in an adapted version of the Posner spatial-cueing paradigm, we investigated the behavioral and neural mechanisms underlying visuospatial orienting/reorienting in depth. At the behavioral level, although covering the same spatial distance, attentional reorienting to objects unexpectedly appearing closer to the observer and in the unattended hemispace was faster than reorienting to unexpected objects farther away. At the neural level, we found that in addition to the classical attentional reorienting system in the right temporoparietal junction, two additional brain networks were differentially involved in aspects of attentional reorienting in depth. First, bilateral premotor cortex reoriented visuospatial attention specifically along the third dimension of visual space (i.e., from close to far or vice versa), compared with attentional reorienting within the same depth plane. Second, a network of areas reminiscent of the human “default-mode network,” including posterior cingulate cortex, orbital prefrontal cortex, and left angular gyrus, was involved in the neural interaction between depth and attentional orienting, by boosting attentional reorienting to unexpected objects appearing both closer to the observer and in the unattended hemispace.
Personality Traits Nexus Employee’s Performance An Application of Big Five Personality Dimensions Model

Performance evaluation is the key area in every era of research and it is influenced through a lot of factors well. As far as the performance of employees is concerned, employee’s personality is the crucial component for organizations success because it influences the performance of employees. This paper investigates the impact of personality traits (Neuroticism, Extraversion, Openness, Agreeableness and Conscientiousness) on employee performance which is measured through quality work, discipline and attention, cooperation among colleagues, responsibility for results and initiative. This study collected data through semi-structured interview which was transcribed for further analysis. The sample includes 12 respondents from the financial and non-financial sector. The respondents were approached through convenient sampling method. QSR Nvivo-10 software was used for data analysis in this study. The study concludes that the big five personality traits have significant impact on the performance of the employees whereas Extraversion, Openness, Agreeableness and Conscientiousness have positive and significant impact on employee performance.