Miracle-dz/UniFAR-FTUs huggingface dataset:
Hot corrosion studies on dissimilar friction welded low alloy steel and austenitic stainless steel under chlorine containing salt deposits under cyclic conditions

High temperature corrosion tests were performed on dissimilar friction weldment of low alloy steel and austenitic stainless steel. Test conditions simulated the environment of a biofuel fired boiler. The samples were exposed to synthetic salt containing 40 wt-%K2SO4, 40 wt-%Na2SO4, 10 wt-%KCl and 10 wt-%NaCl. In the present paper, hot corrosion behaviour of friction welded AISI 4140 and AISI 304 dissimilar materials in molten salt environments at 500, 550 and 600°C was studied. Corrosion was extremely severe on the interface of the dissimilar weldment in molten salt environment. Comparative evaluation was based on the effect of burn-off length and temperature of exposure on hot corrosion behaviour of the dissimilar weldment. Even the interface was attacked through chromium rich phases in hot corrosion environment. The metals formed on the weldment were non-protective.
On Transmission Over Deletion Channels

In this paper, we develop lower bounds on the achievable rate for deletion channels. Deletion channels occur when symbols are randomly dropped, and a subsequence o f th transmitted symbols is received. In deletion channels, unlike erasure channels, there is no s ide-information about which subsequence is received. We show that the achievable rate in deletion chann els differs from that of erasure channels by at mostH0(pd) pd log K K 1 bits, wherepd is the deletion probability, K is the alphabet size and H0( ) is the binary entropy function. We also develop lower bounds for the binary deletion channel that improve the bounds reported in the literature.
RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival

Purpose Contractile activity of the trabecular meshwork (TM) and ciliary muscle (CM) influences aqueous humor drainage; however, the mechanisms linking tissue contractility and regulation of aqueous humor drainage are not well understood. Regulator of G Protein Signaling 2 (RGS2), a GTPase-activating protein of the Gαq family of proteins, plays a critical role in regulation of contractile activity of vascular smooth muscle and in blood pressure homeostasis. To explore a potential role for RGS2 in intraocular pressure (IOP) homeostasis, we evaluated RGS2 knockout (RGS2−/−) mice for changes in IOP. Methods IOP was measured using a rebound tonometer in awake male RGS2−/− and littermate wild-type mice. Histological and immunofluorescence analyses were performed to evaluate changes in the iridocorneal structure, actomyosin organization in CM and TM, and retinal ganglion cell survival in both central and peripheral retina. Results In repeated measurements, IOP was found to be consistently lower in the RGS2−/− mice compared to littermate wild-type mice. This change in IOP appears to be associated with increased actin filament assembly in the CM, and widening of the Schlemm’s canal in the aqueous humor drainage pathway. Furthermore, ganglion cell number in the central retina was found to be significantly higher in the RGS2−/− mice relative to wild-type mice. Conclusions The data suggest that the deficiency of RGS2 decreased IOP, presumably due to increased aqueous humor drainage in association with increased CM contraction. These data indicate a potentially critical role for RGS2 in homeostasis of IOP and for retinal ganglion cell survival.
New Respiratory Viruses and the Elderly

The diagnostics of respiratory viral infections has improved markedly during the last 15 years with the development of PCR techniques. Since 1997, several new respiratory viruses and their subgroups have been discovered: influenza A viruses H5N1 and H1N1, human metapneumovirus, coronaviruses SARS, NL63 and HKU1, human bocavirus, human rhinoviruses C and D and potential respiratory pathogens, the KI and WU polyomaviruses and the torque teno virus. The detection of previously known viruses has also improved. Currently, a viral cause of respiratory illness is almost exclusively identifiable in children, but in the elderly, the detection rates of a viral etiology are below 40%, and this holds also true for exacerbations of chronic respiratory illnesses. The new viruses cause respiratory symptoms like the common cold, cough, bronchitis, bronchiolitis, exacerbations of asthma and chronic obstructive pulmonary disease and pneumonia. Acute respiratory failure may occur. These viruses are distributed throughout the globe and affect people of all ages. Data regarding these viruses and the elderly are scarce. This review introduces these new viruses and reviews their clinical significance, especially with regard to the elderly population.
Hydrogen sulfide reduces cell adhesion and relevant inflammatory triggering by preventing ADAM17‐dependent TNF‐α activation

H2S is the third endogenous gaseous mediator, after nitric oxide and carbon monoxide, possessing pleiotropic effects, including cytoprotection and anti‐inflammatory action. We analyzed, in an in vitro model entailing monocyte adhesion to an endothelial monolayer, the changes induced by H2S on various potential targets, including cytokines, chemokines, and proteases, playing a crucial role in inflammation and cell adhesion. Results show that H2S prevents the increase in monocyte adhesion induced by tumor necrosis factor‐α (TNF‐α). Under these conditions, downregulation of monocyte chemoattractant protein‐1 (MCP‐1), chemokine C‐C motif receptor 2, and increase of cluster of differentiation 36 could be detected in monocytes. In endothelial cells, H2S treatment reduces the increase in MCP‐1, inter‐cellular adhesion molecule‐1, vascular cell adhesion molecule‐1, and of a disintegrin and metalloproteinase metallopeptidase domain 17 (ADAM17), both at the gene expression and protein levels. Cystathionine γ‐lyase and 3‐mercaptopyruvate sulfurtransferase, the major H2S forming enzymes, are downregulated in endothelial cells. In addition, H2S significantly reduces activation of ADAM17 by PMA in endothelial cells, with consequent reduction of both ADAM17‐dependent TNF‐α ectodomain shedding and MCP‐1 release. In conclusion, H2S is able to prevent endothelial activation by hampering endothelial activation, triggered by TNF‐α. The mechanism of this protective effect is mainly mediated by down‐modulation of ADAM17‐dependent TNF‐converting enzyme (TACE) activity with consequent inhibition of soluble TNF‐α shedding and its relevant MCP‐1 release in the medium. These results are discussed in the light of the potential protective role of H2S in pro‐inflammatory and pro‐atherogenic processes, such as chronic renal failure. J. Cell. Biochem. 114: 1536–1548, 2013. © 2013 Wiley Periodicals, Inc.
Actin mutations that show suppression with fimbrin mutations identify a likely fimbrin-binding site on actin

Actin interacts with a large number of different proteins that modulate its assembly and mediate its functions. One such protein is the yeast actin-binding protein Sac6p, which is homologous to vertebrate fimbrin (Adams, A. E. M., D. Botstein, and D. G. Drubin. 1991. Nature (Lond.). 354:404-408. ). Sac6p was originally identified both genetically (Adams, A. E. M., and D. Botstein. 1989. Genetics. 121:675-683.) by dominant, reciprocal suppression of a temperature-sensitive yeast actin mutation (act1-1), as well as biochemically (Drubin, D. G., K. G. Miller, and D. Botstein. 1988. J. Cell Biol. 107: 2551-2561.). To identify the region on actin that interacts with Sac6p, we have analyzed eight different act1 mutations that show suppression with sac6 mutant alleles, and have asked whether (a) these mutations occur in a small defined region on the crystal structure of actin; and (b) the mutant actins are defective in their interaction with Sac6p in vitro. Sequence analysis indicates that all of these mutations change residues that cluster in the small domain of the actin crystal structure, suggesting that this region is an important part of the Sac6p-binding domain. Biochemical analysis reveals defects in the ability of several of the mutant actins to bind Sac6p, and a reduction in Sac6p-induced cross-linking of mutant actin filaments. Together, these observations identify a likely site of interaction of fimbrin on actin.
Training Set Debugging Using Trusted Items

Training set bugs are flaws in the data that adversely affect machine learning. The training set is usually too large for manual inspection, but one may have the resources to verify a few trusted items. The set of trusted items may not by itself be adequate for learning, so we propose an algorithm that uses these items to identify bugs in the training set and thus improves learning. Specifically, our approach seeks the smallest set of changes to the training set labels such that the model learned from this corrected training set predicts labels of the trusted items correctly. We flag the items whose labels are changed as potential bugs, whose labels can be checked for veracity by human experts. To find the bugs in this way is a challenging combinatorial bilevel optimization problem, but it can be relaxed into a continuous optimization problem.Experiments on toy and real data demonstrate that our approach can identify training set bugs effectively and suggest appropriate changes to the labels. Our algorithm is a step toward trustworthy machine learning.
E-Cigarettes: Prevalence and Attitudes in Great Britain

Introduction: Electronic cigarettes (e-cigarettes) are a means of recreational nicotine use that can potentially eliminate the need to smoke tobacco. Little is known about the prevalence of use or smokers’ attitudes toward e-cigarettes. This study describes use of and attitudes toward e-cigarettes in Britain. Methods: Respondents from three surveys were recruited from a panel of adults in Britain. Preliminary online and face-to-face qualitative research informed the development of a smokers’ survey (486 smokers who had used e-cigarettes and 894 smokers who had not). Representative samples of adults in Britain were then constructed from the panel for population surveys in 2010 (12,597 adults, including 2,297 smokers) and 2012 (12,432 adults, including 2,093 smokers), generating estimates of the prevalence of e-cigarette use and trial in Great Britain. Results: Awareness, trial, and current use increased between 2010 and 2012; for example, current use more than doubled from 2.7% of smokers in 2010 to 6.7% in 2012. The proportion of ever-users currently using e-cigarettes was around one-third in both years. In 2012, 1.1% of ex-smokers reported current e-cigarette use, and a further 2.7% reported past use. Approximately 0.5% of never-smokers reported having tried e-cigarettes. Conclusions: While we found evidence supporting the view that e-cigarette use may be a bridge to quitting, we found very little evidence of e-cigarette use among adults who had never smoked. British smokers would benefit from information about the effective use, risks, and benefits of e-cigarettes, as this might enable the use of e-cigarettes to improve public health.
Opinion Dynamics of Elections in Twitter

In this work we conduct an empirical study of opinion time series created from Twitter data regarding the 2008 U.S. elections. The focus of our proposal is to establish whether a time series is appropriate or not for generating a reliable predictive model. We analyze time series obtained from Twitter messages related to the 2008 U.S. elections using ARMA/ARIMA and GARCH models. The first models are used in order to assess the conditional mean of the process and the second ones to assess the conditional variance or volatility. The main argument we discuss is that opinion time series that exhibit volatility should not be used for long-term forecasting purposes. We present an in-depth analysis of the statistical properties of these time series. Our experiments show that these time series are not fit for predicting future opinion trends. Due to the fact that researchers have not provided enough evidence to support the alleged predictive power of opinion time series, we discuss how more rigorous validation of predictive models generated from time series could benefit the opinion mining field.
On Sum Rate and Power Consumption of Multi-User Distributed Antenna System with Circular Antenna Layout

We investigate the uplink of a power-controlled multi-user distributed antenna system (DAS) with antennas deployed on a circle. Applying results from random matrix theory, we prove that for such a DAS, the per-user sum rate and the total transmit power both converge as user number and antenna number go to infinity with a constant ratio. The relationship between the asymptotic per-user sum rate and the asymptotic total transmit power is revealed for all possible values of the radius of the circle on which antennas are placed. We then use this rate-power relationship to find the optimal radius. With this optimal radius, the circular layout DAS (CL-DAS) is proved to offer a significant gain compared with a traditional colocated antenna system (CAS). Simulation results are provided, which demonstrate the validity of our analysis.
A patient-specific algorithm for the detection of seizure onset in long-term EEG monitoring: possible use as a warning device

During long-term electroencephalogram (EEG) monitoring of epileptic patients, a seizure warning system would allow patients and observers to take appropriate precautions. It would also allow observers to interact with patients early during the seizure, thus revealing clinically useful information. We designed patient-specific classifiers to detect seizure onsets. After a seizure and some nonseizure data are recorded in a patient, they are used to train a classifier. In subsequent monitoring sessions, EEG patterns have to pass this classifier to determine if a seizure onset occurs. If it does, an alarm is triggered. Extreme care has been taken to ensure a low false-alarm rate, since a high false-alarm rate would render the system ineffective. Features were extracted from the time and frequency domains and a modified nearest-neighbor (NN) classifier was used. The system reached an onset detection rate of 100% with an average delay of 9.35 s after onset. The average false-alarm rate was only 0.02/h. The method was evaluated in 12 patients with a total of 47 seizures. Results indicate that the system is effective and reasonably reliable. Computation load has been kept to a minimum so that real-time processing is possible.
Immune Defenses of the Invasive Apple Snail Pomacea canaliculata (Caenogastropoda, Ampullariidae): Phagocytic Hemocytes in the Circulation and the Kidney

Hemocytes in the circulation and kidney islets, as well as their phagocytic responses to microorganisms and fluorescent beads, have been studied in Pomacea canaliculata, using flow cytometry, light microscopy (including confocal laser scanning microscopy) and transmission electron microscopy (TEM). Three circulating hemocyte types (hyalinocytes, agranulocytes and granulocytes) were distinguished by phase contrast microscopy of living cells and after light and electron microscopy of fixed material. Also, three different populations of circulating hemocytes were separated by flow cytometry, which corresponded to the three hemocyte types. Hyalinocytes showed a low nucleus/cytoplasm ratio, and no apparent granules in stained material, but showed granules of moderate electron density under TEM (L granules) and at least some L granules appear acidic when labeled with LysoTracker Red. Both phagocytic and non-phagocytic hyalinocytes lose most (if not all) L granules when exposed to microorganisms in vitro. The phagosomes formed differed whether hyalinocytes were exposed to yeasts or to Gram positive or Gram negative bacteria. Agranulocytes showed a large nucleus/cytoplasm ratio and few or no granules. Granulocytes showed a low nucleus/cytoplasm ratio and numerous eosinophilic granules after staining. These granules are electron dense and rod-shaped under TEM (R granules). Granulocytes may show merging of R granules into gigantic ones, particularly when exposed to microorganisms. Fluorescent bead exposure of sorted hemocytes showed phagocytic activity in hyalinocytes, agranulocytes and granulocytes, but the phagocytic index was significantly higher in hyalinocytes. Extensive hemocyte aggregates ('islets') occupy most renal hemocoelic spaces and hyalinocyte-like cells are the most frequent component in them. Presumptive glycogen deposits were observed in most hyalinocytes in renal islets (they also occur in the circulation but less frequently) and may mean that hyalinocytes participate in the storage and circulation of this compound. Injection of microorganisms in the foot results in phagocytosis by hemocytes in the islets, and the different phagosomes formed are similar to those in circulating hyalinocytes. Dispersed hemocytes were obtained after kidney collagenase digestion and cell sorting, and they were able to phagocytize fluorescent beads. A role for the kidney as an immune barrier is proposed for this snail.
Toward an understanding of the motivation of open source software developers

An Open Source Software (OSS) project is unlikely to be successful unless there is an accompanied community that provides the platform for developers and users to collaborate. Members of such communities are volunteers whose motivation to participate and contribute is of essential importance to the success of OSS projects. In this paper, we aim to create an understanding of what motivates people to participate in OSS communities. We theorize that learning is one of the motivational forces. Our theory is grounded in the learning theory of Legitimate Peripheral Participation, and is supported by analyzing the social structure of OSS communities and the co-evolution between OSS systems and communities. We also discuss practical implications of our theory for creating and maintaining sustainable OSS communities as well as for software engineering research and education.
Hearing the shape of a triangle

In 1966 Mark Kac asked the famous question 'Can one hear the shape of a drum? '. While this was later shown to be false in general, it was proved by C. Durso that one can hear the shape of a triangle. After an introduction to the general inverse spectral problem we will give a new proof of this fact. The central point of the argument is to show that area, perimeter and the sum of the reciprocals of the angles determine a triangle uniquely. This is proved using convexity arguments and the partial fraction expansion of $\sin^{-2}x$.
Comparison of postoperative pain and inflammation reaction in dogs undergoing preventive laparoscopic-assisted and incisional gastropexy

This study compared the effects of postoperative pain and inflammation reaction after preventive laparoscopic-assisted gastropexy (LAG) and incisional gastropexy (IG) in 10 clinically normal Beagles. Surgical time, incision length, visual analog scale (VAS) score, University of Melbourne Pain Scale (UMPS) score, and plasma C-reactive protein (CRP), plasma cortisol (COR), and serum interleukin-6 (IL-6) levels were evaluated. The VAS and UMPS scores and COR and IL-6 levels were recorded at 0.5, 1, 2, 4, 8, 12, 18 and 24 hr after surgery. CRP level was recorded at 12, 24 and 48 hr after surgery. The VAS and UMPS scores showed no significant intergroup differences. Compared to IG, LAG had significantly lower surgical time (45 ± 9.91 min vs 64 ± 5.30 min; P<0.05), incision length (46 ± 8.21 mm vs 129 ± 19.49 mm; P<0.05), CRP level (12 hr after surgery; 4.58 ± 1.58 mg/dl vs 12.4 ± 1.34 mg/dl; P<0.01), and COR level (1 hr after surgery; 10.79 ± 3.07 µg/dl vs 15.9 ± 3.77 µg/dl; P<0.05). IL-6 levels showed no significant intergroup differences at any time point. However, LAG resulted in lower IL-6 levels than did IG at all postoperative time points. Neither procedure resulted in significant surgical complications. LAG produced lower surgical stress than did IG, suggesting that LAG is a safe, minimally invasive, and highly useful technique for preventing canine gastric dilatation-volvulus. Nevertheless, since this study used experimental models, its usefulness should be evaluated in future cases.
Removal of Bikini Hair by Rapid 810-nm Diode Laser

nwanted hair has traditionally been removed by wax, tweezers, shaving, chemical depilatories, or electrolysis. These techniques are time consuming, monotonous, painful, and have limited efficacies. Electrolysis, once a popular procedure for permanent hair removal, is invasive, tedious, and only partially effective and can result in scarring or postinflammatory hyperpigmentation. Laser and light-based devices offer alternatives to traditional physical methods and have gained considerable popularity. In 2006, removal of hair by a laser device was the third most frequently performed nonsurgical cosmetic procedure in the United States. Laser and light-based modalities destroy hair follicles by selective photothermolysis (SP), in which melanin in the hair shaft and surrounding follicular epithelium is the target chromophore. When red and near-infrared wavelengths penetrate deeply into the dermis and are selectively absorbed by melanin, thermal damage is restricted to the hair follicles as a result of SP. The application of SP for laser hair removal was first described in 1996 by Grossman et al. Since then, use of the ruby, alexandrite, Nd:YAG, and diode laser devices for hair removal have been evaluated and reviewed in detail. The purpose of the study described in this article was to evaluate the efficacy and safety of a new, high-speed, very long-pulsed 810-nm diode laser for the rapid removal of hair from the bikini area.
Vestibular Evoked Myogenic Potentials in Acute Acoustic Trauma

Objectives: Anatomical proximity of the saccule to the stapedial footplate points to the possibility of acoustic trauma associated with saccular dysfunction. Therefore, it was the authors' premise that abnormal vestibular evoked myogenic potential (VEMP) after acute acoustic trauma may be caused by saccular damage from very high intensity noise; consequently, irreversible hearing loss ensued. The aim of this study was to investigate the VEMP responses in those with acute acoustic trauma. Study Design: A prospective study. Setting: University hospital. Patients: Twenty patients (29 ears) without previous ear disorders diagnosed as acute acoustic trauma were enrolled in this study. Main Outcome Measures: Before treatment, each patient underwent pure tone audiometry and caloric and VEMP tests. Correlations between the hearing outcome and mean hearing level, sources of noise, caloric responses, or VEMP results were investigated. Results: After 3 months of medication, complete recovery was achieved in 4 ears and hearing improvement in 4 ears, whereas hearing in 21 ears (72%) remained unchanged. Eighteen ears presenting normal VEMPs revealed hearing improvement in eight ears (44%) and unchanged hearing in ten ears (56%). However, hearing loss remained unchanged in all 11 ears (100%) with absent or delayed VEMPs, exhibiting a significant relationship between VEMP results and hearing outcome. Thus, VEMP test can predict the hearing outcome after acute acoustic trauma with a sensitivity of 44% and a specificity of 100%. Conclusion: The greater the noise intensity, the severer damage on the cochlea and saccule is shown. Absent or delayed VEMPs in ears after acute acoustic trauma may indicate poor prognosis with respect to hearing improvement, whereas normal VEMP is not a powerful indicator for expectation of hearing improvement.