Miracle-dz/UniFAR-FTUs huggingface dataset:
Response of Russian Wheat Aphid Resistance in Wheat and Barley to Four Diuraphis (Hemiptera: Aphididae) Species

ABSTRACT Three Diuraphis species, Diuraphis frequens (Walker), Diuraphis mexicana (McVicar Baker), and Diuraphis tritici (Gillette), were known to exist in the United States before the 1986 appearance of the Russian wheat aphid, Diuraphis noxia Kurdjumov. The Russian wheat aphid soon became a significant pest of wheat although other endemic Diuraphis species were known to infest wheat. Wheat and barley entries resistant and susceptible to Russian wheat aphid biotype 2 were evaluated against all four Diuraphis species to determine their host interrelationships. Leaf chlorosis, leaf roll, leaf number, plant height, and infestation levels were assessed 21 d after the plants were infested by aphids in a no-choice caged environment. D. mexicana was unable to survive on wheat by 21 d after infestation and effects on the plant damage variables were negligible. D. frequens survived at low levels on resistant and susceptible plant entries and had a low impact on plant damage and growth. Russian wheat aphid biotype 2 and D. tritici were damaged most wheat and barley lines except the Russian wheat aphid biotype 2-resistant wheat lines containing genes from Dn7, STARS 2414-11, and CI2401; and resistant barley containing genes from STARS 9577B and 9301B. Russian wheat aphid biotype 2 and D. tritici reduced the growth of resistant plants by 25–50% and susceptible entries by 65–75%. Reductions at this level are typical under no-choice studies but resistant cultivars do not have these reductions under field conditions. The Russian wheat aphid biotype 2 resistant wheat lines would be effective in managing both wheat pest species.
Knowledge Discovery in Gene Expression Data via Evolutionary Algorithms

Methods currently used for micro-array data classification aim to select a minimum subset of features, namely a predictor, that is necessary to construct a classifier of best accuracy. Although effective, they lack in facing the primary goal of domain experts that are interested in detecting different groups of biologically relevant markers. In this paper, we present and test a framework which aims to provide different subsets of relevant genes. It considers initial gene filtering to define a set of feature spaces each of ones is further refined by taking advantage from a genetic algorithm. Experiments show that the overall process results in a certain number of predictors with high classification accuracy. Compared to state-of-art feature selection algorithms, the proposed framework consistently generates better feature subsets and keeps improving the quality of selected subsets in terms of accuracy and size.
Emotional Labor

The occupational experience of workers in service-oriented jobs can have profound effects on their health and well being, such as burnout, inauthenticity, and job dissatisfaction. The growing service economy and resultant proliferation of service-oriented jobs in current times and in the future must be acknowledged and investigated. The move from an economy driven by manufacturing industries to one dominated by service industries has taken place and currently prevails in the United States. In recognizing this shift in the "work" experience of the American work force, the changing nature of work related hazards must also be considered. Emotional labor has come to be known as an appreciable aspect of work involving direct interactions with clients and customers that can lead to adverse psychosocial outcomes. These relationships reveal the potential unpleasantness of service employment in which the performance of emotional labor is unavoidable. Although worker attributes can influence the emotional experience on the job, emotional labor is also likely to threaten the well being of workers through significantly high demands to express organizationally desired emotions and low control over what emotions can be felt and displayed. Recognition and investigation of emotional labor is necessary to understand its effects on worker populations. Conceptual models featuring emotional labor are available to guide research. However, discrimination among them based on utility and application in relation to identified study objectives and needs is essential.
Randomized Effectiveness Trial of a Brief Course of Acupuncture for Posttraumatic Stress Disorder

Background:Initial posttraumatic stress disorder (PTSD) care is often delayed and many with PTSD go untreated. Acupuncture appears to be a safe, potentially nonstigmatizing treatment that reduces symptoms of anxiety, depression, and chronic pain, but little is known about its effect on PTSD. Methods:Fifty-five service members meeting research diagnostic criteria for PTSD were randomized to usual PTSD care (UPC) plus eight 60-minute sessions of acupuncture conducted twice weekly or to UPC alone. Outcomes were assessed at baseline and 4, 8, and 12 weeks postrandomization. The primary study outcomes were difference in PTSD symptom improvement on the PTSD Checklist (PCL) and the Clinician-administered PTSD Scale (CAPS) from baseline to 12-week follow-up between the 2 treatment groups. Secondary outcomes were depression, pain severity, and mental and physical health functioning. Mixed model regression and t test analyses were applied to the data. Results:Mean improvement in PTSD severity was significantly greater among those receiving acupuncture than in those receiving UPC (PCL&Dgr;=19.8±13.3 vs. 9.7±12.9, P<0.001; CAPS&Dgr;=35.0±20.26 vs. 10.9±20.8, P<0.0001). Acupuncture was also associated with significantly greater improvements in depression, pain, and physical and mental health functioning. Pre-post effect-sizes for these outcomes were large and robust. Conclusions:Acupuncture was effective for reducing PTSD symptoms. Limitations included small sample size and inability to parse specific treatment mechanisms. Larger multisite trials with longer follow-up, comparisons to standard PTSD treatments, and assessments of treatment acceptability are needed. Acupuncture is a novel therapeutic option that may help to improve population reach of PTSD treatment.
High-dose chemo-radiotherapy followed by autologous Philadelphia chromosome-negative blood progenitor cell transplantation in patients with chronic myelogenous leukemia.

Twenty-three patients with chronic myelogenous leukemia in early chronic phase (ECP) and not previously treated with alpha-interferon (IFN-alpha) (10 patients), in ECP but pretreated with IFN-alpha (<12 months) (seven patients) and in late chronic phase (LCP) pretreated with IFN-alpha (>12 months) (six patients) underwent autografting with Philadelphia (Ph) chromosome-negative blood progenitor cells (BPCs) (20 patients), or partially/totally Ph-positive BPCs (three patients), previously mobilized during the early phase of recovery after aplasia induced by intensive chemotherapy. The conditioning regimen consisted of high-dose chemotherapy alone or followed by total body irradiation (TBI). Recombinant G-CSF was given after BPCs infusion on day +8. All patients in ECP not pretreated with IFN-alpha are alive and five of them are Ph-negative in the marrow after autografting. Six of seven patients autografted with Ph-negative BPCs in the group of ECP pretreated with IFN-alpha (<12 months) are alive and two of them are still Ph-negative in the marrow. In the same group, the only patient transplanted with partially Ph-positive BPCs, died of blastic transformation 2 months after reinfusion. Three patients (two patients autografted with Ph-negative BPCs and one patient with Ph-positive BPC) in the group of LCP pretreated with IFN-alpha >12 months are alive but Ph-positive after autografting. The other three patients of the same group died of procedure-related toxicity (two patients) and blastic transformation (one patient). Seventeen patients (10/10 ECP not pretreated with IFN-alpha; 5/7 ECP pretreated with IFN-alpha and 2/6 LCP pretreated with IFN-alpha) of 23 autografted patients were treated with IFN-alpha +/- IL-2. Toxicities after autografting were mostly related to myelosuppression, particularly thrombocytopenia. All patients of the two groups pretreated with IFN-alpha developed febrile episodes during the aplastic phase following BPCs reinfusion. No patient autografted in ECP and those not pretreated with IFN-alpha developed febrile episodes. This is also probably due to the use of i.v. antibiotic and antimicotic prophylaxis when neutrophils were < or = 1 x 10(9)/l after autografting. Greater toxicity was observed in patients pretreated with IFN-alpha, being lethal in two cases in LCF. In conclusion, the "in vivo' manipulation approach employed in our institution is a safe procedure and it results in a high collection of Ph-negative cells in the blood if the cells are harvested: (1) in early chronic phase; (2) in early phase of recovery after chemotherapy-inducing aplasia; (3) in patients not extensively pretreated with IFN-alpha. The data presented here have shown encouraging trends in chronic phase of CML and offer new perspective for patients without an HLA-identical donor or for patients who do not respond to IFN-alpha.
PERAN EFIKASI DIRI DALAM MEMEDIASI PENGARUH PENDIDIKAN KEWIRAUSAHAAN TERHADAP NIAT BERWIRAUSAHA

Dewasa ini, banyak generasi muda menjadi pengangguran, sehingga menumbuhkan jiwa kewirausahaan dipercaya sebagai alternatif mengatasi keterbatasan lapangan pekerjaan dan mengurangi jumlah pengangguran. Penelitian ini bertujuan mengetahui faktor pendidikan kewirausahaan dan efikasi diri terhadap niat berwirausaha mahasiswa S1 Fakultas Ekonomi dan Bisnis Universitas Udayana. Penelitian ini dilakukan di Fakultas Ekonomi dan Bisnis Universitas Udayana. Sampel diambil sebanyak 100 responden, metode penentuan sampel purposive sampling dengan teknik analisis jalur dan uji sobel. Hasil penelitian menunjukkan pendidikan kewirausahaan berpengaruh positif dan signifikan terhadap niat berwirausaha, pendidikan kewirausahaan juga berpengaruh positif dan signifikan terhadap efikasi diri, variabel intervening efikasi diri memiliki pengaruh positif dan signifikan terhadap niat berwirausaha, dan efikasi diri memediasi secara signifikan pengaruh pendidikan kewirausahaan terhadap niat berwirausaha. Pihak Fakultas Ekonomi dan Bisnis Universitas Udayana disarankan mengembangkan program pendidikan kewirausahaan selain bersifat teori juga diimbangi dengan soft skill untuk meningkatkan niat berwirausaha sehingga mahasiswa memiliki efikasi diri memilih karir sebagai wirausahawan.
Best practices for describing, consuming, and discovering web services: a comprehensive toolset

The service‐oriented computing (SOC) paradigm has recently gained a lot of attention in the software industry because SOC represents a novel and a fresh way of architecting distributed applications. SOC is usually materialized via web services, which allows developers to structure applications exposing a clear, public interface to their capabilities. Although conceptually and technologically mature, SOC still lacks adequate development support from a methodological point of view. In this paper, we present the EasySOC project, a set of guidelines to simplify the development of service‐oriented applications and services. EasySOC is a synthesized catalog of best SOC development practices that arise as a result of several years of research in fundamental Services Computing topics, that is, Web Service Description Language‐based technical specification, Web Service discovery, and Web Service outsourcing. In addition, we describe a materialization of the guidelines for the Java language, which has been implemented as a plug‐in for the Eclipse IDE. We believe that both the practical nature of the guidelines and the availability of this software that enforces them may help software practitioners to rapidly exploit our ideas for building real SOC applications. Copyright © 2012 John Wiley & Sons, Ltd.
Pronoun case overextensions and paradigm building

ABSTRACT Pronoun case errors, or overextensions, like *me want it are characteristic of English child language. This paper explores a hypothesis that the morphological structure of a pronoun influences the pattern of these errors. The Language Acquisition Device (LAD) attempts to analyse English pronoun case forms into stems and affixes, but cannot because of their irregularity. Nevertheless the LAD extracts a phonetic core for each pronoun (e.g. /m-/ for the ist sg., /h-/ for the 3rd masc. sg.). The phonetic core blocks the overextension of suppletive nominative forms like I and she. This hypothesis predicts strong differences in the frequency and types of errors between pronouns with suppletive nominatives and those without. Evidence for this hypothesis was found in a transcript database of twelve children, with data collected in one hour samples every month from 1;0 to 3;0. 20,908 pronouns were examined, 1347 of which were errors. Statistical analyses of these data provide support for this hypothesis.
Stability of a generalized Jensen equation on restricted domains

In this paper, we establish the conditional Hyers-Ulam-Rassias stability of the generalized Jensen functional equation r f � sx+ty r � = s g(x) + t h(y) on various restricted domains such as inside balls, outside balls, and punctured spaces. In addition, we prove the orthogonal stability of this equa- tion and study orthogonally generalized Jensen mappings on Balls in inner product spaces.
The influence of foam rolling on recovery from exercise-induced muscle damage.

The purpose of this study was to examine the impact of foam rolling (FR) on recovery from exercise-induced muscle damage (EIMD). Thirty-seven males performed 40 x 15 m sprints, inducing muscle damage. Immediately following sprinting and in the four days following, perceived muscle soreness, hip abduction range of motion (ROM), hamstring muscle length, vertical jump, and agility measures were recorded. Eighteen subjects (mean ± sd; age 22.4 ± 2.0 yrs; BMI 26.9 ± 4.2 kgm) foam rolled prior to testing each day (FR), while 19 (mean ± sd; age 23.2 ± 3.2 yrs; BMI 26.3 ± 4.0 kgm) served as a non-foam rolling control (CON). Measurements recorded during the five days of recovery from the repeated sprint protocol were compared to week one baseline measurements. The area under the curve (AUC) was calculated by summing all five scores as they changed from baseline measurement, and these data were compared by condition using a two-tailed Mann-Whitney U test (alpha level = 0.05). Perceived soreness, hip abduction ROM, hamstring muscle length, and vertical jump were not significantly different between groups (p ≥ 0.25). Agility was less impaired in the FR condition (p = 0.0049) as AUC was higher in CON (2.88 s ± 2.45) than FR (0.33 s ± 2.16). Based upon these data, FR appears to expedite recovery of agility following EIMD instigated by a repeated sprint protocol. FR may be useful for athletes requiring adequate agility who need to recover quickly from demanding bouts of exercise.
Treatment of dermatophytosis in young cattle with propolis and Whitfield's ointment

DERMATOPHYTOSIS in cattle is usually caused by the fungus Trichophyton species, which infects the keratinised tissues of the skin ([Scott 1988][1], [Rochette and others 2003][2], [Radostits and others 2007][3]). Dermatophytosis is usually enzootic in herds and is more prevalent in animals less than
Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.

The cblG and cblC disorders of cobalamin (Cbl) metabolism are two inherited causes of megaloblastic anaemia. In cblG, mutations in methionine synthase (MTR) decrease conversion of hydroxocobalamin (HOCbl) to methylcobalamin, while in cblC, mutations in MMACHC disrupt formation of cob(II)alamin (detected as HOCbl). Cases with undetectable methionine synthase (MS) activity are extremely rare and classified as 'cblG-variant'. In four 'cblG-variant' cases, we observed a decreased conversion of cyanocobalamin to HOCbl that is also seen in cblC cases. To explore this observation, we studied the gene defects, splicing products and expression of MS, as well as MS/MMACHC protein interactions in cblG-variant, cblG, cblC and control fibroblasts. We observed a full-size MS encoded by MTR-001 and a 124 kDa truncated MS encoded by MTR-201 in cblG, cblC, control fibroblasts and HEK cells, but only the MTR-201 transcript and inactive truncated MS in cblG-variant cells. Co-immunoprecipitation and proximity ligation assay showed interaction between truncated MS and MMACHC in cblG-variant cells. This interaction decreased 2.2, 1.5 and 5.0-fold in the proximity ligation assay of cblC cells with p.R161Q and p.R206W mutations, and HEK cells with knock down expression of MS by siRNA, respectively, when compared with control cells. In 3D modelling and docking analysis, both truncated and full-size MS provide a loop anchored to MMACHC, which makes contacts with R-161 and R-206 residues. Our data suggest that the interaction of MS with MMACHC may play a role in the regulation of the cellular processing of Cbls that is required for Cbl cofactor synthesis.
An analysis of the effects of composite objectives in multiobjective software module clustering

The application of multiobjective optimization to address Software Engineering problems is a growing trend. Multiobjective algorithms provide a balance between the ability of the computer to search a large solution space for valuable solutions and the capacity of the human decision-maker to select an alternative when two or more incomparable objectives are presented. However, when more than a single objective is available, the set of objectives to be considered by the search becomes part of the decision. In this paper, we address the efficiency and effectiveness of using two composite objectives while searching solutions for the software clustering problem. We designed an experimental study which shows that a multiobjective genetic algorithm can find a set of solutions with increased quality and using less processing time if these composite objectives are suppressed from the formulation for the software clustering problem.
Repurposing FDA-approved drugs to combat drug-resistant Acinetobacter baumannii.

OBJECTIVE The rising occurrence of drug-resistant pathogens accentuates the need to identify novel antibiotics. We wanted to identify new scaffolds for drug discovery by repurposing FDA-approved drugs against Acinetobacter baumannii, an emerging Gram-negative nosocomial drug-resistant pathogen. MATERIALS AND METHODS In this study, we screened 1040 FDA-approved drugs against drug-susceptible A. baumannii ATCC 17978 and drug-resistant A. baumannii BAA-1605. RESULTS AND DISCUSSION Twenty compounds exhibited significant antimicrobial activity (MIC ≤8 mg/L) against ATCC 17978 while only five compounds showed such activity against BAA-1605. Among the most notable results, tyrothricin, a bactericidal antibiotic typically active only against Gram-positive bacteria, exhibited equipotent activity against both strains. CONCLUSION The paucity of identified compounds active against drug-resistant A. baumannii exemplifies its ability to resist antimicrobials as well as the resilience of drug-resistant Gram-negative pathogens. Repurposing of approved drugs is a viable alternative to de novo drug discovery and development.
Prevalence of Helicobacter Pylori Infection among Children in Rasht, Northern Iran

bAckground Helicobacter pylori (H. pylori) infection usually occurs during childhood, especially in developing countries. The aim of this study was to evaluate the prevalence of H. pylori infection among children in primary schools of Rasht, a northern Iranian city. Methods This cross-sectional study was conducted among 961 primary school students in Rasht. Samples were randomly selected and stored at -20o C until analysis. The stool assay was performed using the HP AgT kit. r esults Overall 475 boys and 486 girls, aged 7 to 11 years were evaluated. A total of 384 (40%) children were diagnosed as H. pylori positive by the stool test. A higher prevalence of H. pylori was found in the stools of individuals who consumed well water and municipal tap water when compared to boiled water (p<0.05). There was no significant difference between the rate of H. pylori infection and individuals’ ages, gender or socioeconomic levels.
Plasma progesterone profile and conception rate following exogenous supplementation of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone releasing intra-vaginal device in repeat-breeder crossbred cows

Aim: This study was designed to evaluate the effect of gonadotropin-releasing hormone (GnRH), human chorionic gonadotropin (hCG), and progesterone impregnated intra-vaginal device on progesterone profile and conception rate in repeat-breeding crossbred cows. Materials and Methods: Repeat-breeding crossbred cows aged 3-8 years (n=32), lactating and negative to white side test were randomly divided into four groups: Group 1 (Control, n=8), Group 2 (GnRH at 10 µg i.m, n=8), Group 3 (hCG at 1500 IU i.m., n=8), and Group 4 (progesterone impregnated intra-vaginal device at 958 mg, n=8). All the treatme nts were given on 5th daypostbreeding and in Group 4 intra-vaginally implanted device was withdrawn on 9th day (i.e., implant inserted for total 4 days) of the estrous cycle. Blood samples were collected on day 0, 5, 10, 15, and day 20 of estrous cycle, and plasma was separated for progesterone estimation. Results: Accessory corpus luteum was not formed in crossbred cows of Group4 and control group. However, total 6 and 8 accessory corpora lutea were found in Group 2 and Group 3, respectively. In pregnant cows, the plasma progesterone concentration increased continuously from day 0 to day 20. In non-pregnant cows, it increased from day 0 to day 15 and then declined. The conception rate on day 60 in Group 1, Group 2, Group 3, and Group 4 was 37.5%, 50%, 75%, and 37.5%, respectively. Conclusions: Treating repeat-breeder cows with hCG is effective in increasing conception rate by developing accessory corpora lutea and higher progesterone level.
Hybrid Algorithm for Floorplanning Using B*-tree Representation

Floorplanning is an important step in the physical design of VLSI circuits. Since the variety of packing is uncountable, it is hard to be solved exactly in practical applications. The key issue is how to find the optimal solution in the finite solution space. In this paper, we proposed hybrid algorithm which based on B*-tree representation to improve the area utilization. The simulated annealing was embedded into tabu search for floorplanning. Experimental results show that our approach can improve the area utilization in shorter time. As we can see from the experimental results, we can improve area utilization and obtain the optimal results in a short runtime. It shows that the method we proposed is effective and efficient.
Neuronal Markers in Allergic Rhinitis: Expression and Correlation With Sensory Testing

Introduction: Although the role of immunoglobulin E‐mediated hypersensitivity reactions in allergic rhinitis is well known, the relative contribution of sensory nerves to the symptoms of rhinitis is uncertain. This study looked at the level of specific neuronal markers including the nerve marker protein gene product 9.5 (PGP 9.5), sensory and autonomic neuropeptides, the capsaicin/heat receptor TRPV1, and nerve growth factor (NGF) in patients with allergic rhinitis and controls and their correlation with nasal sensitivity.