Miracle-dz/UniFAR-FTUs huggingface dataset:
What Explains Rwanda's Drop in Fertility between 2005 and 2010?

Following a decade-and-a-half stall, fertility in Rwanda dropped sharply between 2005 and 2010. Using a hierarchical age-period-cohort model, this paper finds that the drop in fertility is largely driven by cohort effects, with younger cohorts having substantially fewer children than older cohorts observed at the same age. An Oaxaca-Blinder decomposition is applied on two successive rounds of the Demographic and Health Survey. The findings show that improved female education levels account for the largest part of the fertility decline, with improving household living standards and the progressive move toward non-agricultural employment being important secondary drivers. The drop in fertility has been particularly salient for the younger cohorts, for whom the fertility decline can be fully explained by changes in underlying determinants, most notably the large increase in educational attainment between 2005 and 2010.
$\alpha$ -Divergence Is Unique, Belonging to Both  $f$-Divergence and Bregman Divergence Classes

A divergence measure between two probability distributions or positive arrays (positive measures) is a useful tool for solving optimization problems in optimization, signal processing, machine learning, and statistical inference. The Csiszar f-divergence is a unique class of divergences having information monotonicity, from which the dual alpha geometrical structure with the Fisher metric is derived. The Bregman divergence is another class of divergences that gives a dually flat geometrical structure different from the alpha-structure in general. Csiszar gave an axiomatic characterization of divergences related to inference problems. The Kullback-Leibler divergence is proved to belong to both classes, and this is the only such one in the space of probability distributions. This paper proves that the alpha-divergences constitute a unique class belonging to both classes when the space of positive measures or positive arrays is considered. They are the canonical divergences derived from the dually flat geometrical structure of the space of positive measures.
Limited Recovery of β-Cell Function After Gastric Bypass Despite Clinical Diabetes Remission

The mechanisms responsible for the remarkable remission of type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) are still puzzling. To elucidate the role of the gut, we compared β-cell function assessed during an oral glucose tolerance test (OGTT) and an isoglycemic intravenous glucose clamp (iso-IVGC) in: 1) 16 severely obese patients with type 2 diabetes, up to 3 years post-RYGBP; 2) 11 severely obese normal glucose-tolerant control subjects; and 3) 7 lean control subjects. Diabetes remission was observed after RYGBP. β-Cell function during the OGTT, significantly blunted prior to RYGBP, normalized to levels of both control groups after RYGBP. In contrast, during the iso-IVGC, β-cell function improved minimally and remained significantly impaired compared with lean control subjects up to 3 years post-RYGBP. Presurgery, β-cell function, weight loss, and glucagon-like peptide 1 response were all predictors of postsurgery β-cell function, although weight loss appeared to be the strongest predictor. These data show that β-cell dysfunction persists after RYGBP, even in patients in clinical diabetes remission. This impairment can be rescued by oral glucose stimulation, suggesting that RYGBP leads to an important gastrointestinal effect, critical for improved β-cell function after surgery.
Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria

Background. Host responses to infection are critical determinants of disease severity and clinical outcome. The development of tools to risk stratify children with malaria is needed to identify children most likely to benefit from targeted interventions. Methods. This study investigated the kinetics of candidate biomarkers of mortality associated with endothelial activation and dysfunction (angiopoietin-2 [Ang-2], soluble FMS-like tyrosine kinase-1 [sFlt-1], and soluble intercellular adhesion molecule-1 [sICAM-1]) and inflammation (10 kDa interferon γ-induced protein [CXCL10/IP-10] and soluble triggering receptor expressed on myeloid cells-1 [sTREM-1]) in the context of a randomized, double-blind, placebo-controlled, parallel-arm trial evaluating inhaled nitric oxide versus placebo as adjunctive therapy to parenteral artesunate for severe malaria. One hundred eighty children aged 1–10 years were enrolled at Jinja Regional Referral Hospital in Uganda and followed for up to 6 months. Results. There were no differences between the 2 study arms in the rate of biomarker recovery. Median levels of Ang-2, CXCL10, and sFlt-1 were higher at admission in children who died in-hospital (n = 15 of 180; P < .001, P = .027, and P = .004, respectively). Elevated levels of Ang-2, sTREM-1, CXCL10, and sICAM-1 were associated with prolonged clinical recovery times in survivors. The Ang-2 levels were also associated with postdischarge mortality (P < .0001). No biomarkers were associated with neurodisability. Conclusions. Persistent endothelial activation and dysfunction predict survival in children admitted with severe malaria.
The Role of Market Discipline on Bank Capital Buffer: Evidence from a Sample of European Banks

Using a sample of European commercial banks over the period 1993-2006, we show that market discipline significantly and positively affects banks' capital buffer. By distinguishing junior from senior debt holders, we find that both types of investors exert a pressure on banks to hold more capital but that the pressure exerted by junior debt holders is higher. Furthermore, junior debt holders exert a pressure on banks whatever the importance of their non-traditional activities. By contrast, we find that senior debt holders exert a pressure only on banks that are heavily involved in non-traditional activities that are badly taken into account in the current bank capital regulation framework. These results might help us to better understand the role of market discipline as a complement to capital regulation.
Mesovortices, Polygonal Flow Patterns, and Rapid Pressure Falls in Hurricane-Like Vortices

Abstract The present work considers the two-dimensional barotropic evolution of thin annular rings of enhanced vorticity embedded in nearly irrotational flow. Such initial conditions imitate the observed flows in intensifying hurricanes. Using a pseudospectral numerical model, it is found that these highly unstable annuli rapidly break down into a number of mesovortices. The mesovortices undergo merger processes with their neighbors and, depending on initial conditions, they can relax to a monopole or an asymmetric quasi-steady state. In the latter case, the mesovortices form a lattice rotating approximately as a solid body. The flows associated with such vorticity configurations consist of straight line segments that form a variety of persistent polygonal shapes. Associated with each mesovortex is a local pressure perturbation, or mesolow. The magnitudes of the pressure perturbations can be large when the magnitude of the vorticity in the initial annulus is large. In cases where the mesovortices merge to.
Effects of sensory-enhanced yoga on symptoms of combat stress in deployed military personnel.

OBJECTIVE We examined the effects of sensory-enhanced hatha yoga on symptoms of combat stress in deployed military personnel, compared their anxiety and sensory processing with that of stateside civilians, and identified any correlations between the State-Trait Anxiety Inventory scales and the Adolescent/Adult Sensory Profile quadrants. METHOD Seventy military personnel who were deployed to Iraq participated in a randomized controlled trial. Thirty-five received 3 wk (≥9 sessions) of sensory-enhanced hatha yoga, and 35 did not receive any form of yoga. RESULTS Sensory-enhanced hatha yoga was effective in reducing state and trait anxiety, despite normal pretest scores. Treatment participants showed significantly greater improvement than control participants on 16 of 18 mental health and quality-of-life factors. We found positive correlations between all test measures except sensory seeking. Sensory seeking was negatively correlated with all measures except low registration, which was insignificant. CONCLUSION The results support using sensory-enhanced hatha yoga for proactive combat stress management.
Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas

Telomere length maintenance is regarded as a fundamental step in tumorigenesis, as most human brain tumors, including meningiomas, stabilize the ends of their chromosomes using telomerase. This investigation represents an introduction to telomerase expression in canine and feline meningiomas. Twenty-five archived cases (14 dogs and 11 cats) were immunohistochemically tested for human-telomerase reverse transcriptase (h-TERT), scored, and quantified; furthermore, mitoses were counted on sections stained with a modified toluidine blue. The h-TERT antibody immunolabelled the nucleus and nucleolus of meningeal neoplastic cells, with an intensity ranging from mild to strong and a speckled distribution; a significantly higher expression in cats was noted, while no significant association between h-TERT immunolabelling and sex or histotype was evident in dogs or cats. The telomerase enzyme represents a fundamental parameter of potential malignant transformation, which may occur independently of the signal to proliferate, thereby supplying the cells with unlimited growth capabilities. Telomerase expression could be a prognostic indicator independent of the kinetic parameters, although this should be evaluated using a larger dataset with available clinical information.
ELECTROPHYSIOLOGICAL CORRELATES OF IMPAIRED READING IN DYSLEXIC CHILDREN

1 Cognitive Neuroscience Research Group, Departamento de Psicologia, & Institute of Biotechnology & Bioengineering, Centre for Molecular and Structural Biomedicine, Universidade do Algarve, Faro, Portugal. 2 Cognitive Neurophysiology Research Group, Stockholm Brain Institute, Karolinska Institutet, Stockholm, Sweden. 3 Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands 4 Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
Homeostatic regulation of adult hippocampal neurogenesis in aging rats: long-term effects of early exercise

Adult neurogenesis is highly responsive to environmental and physiological factors. The majority of studies to date have examined short-term consequences of enhancing or blocking neurogenesis but long-term changes remain less well understood. Current evidence for age-related declines in neurogenesis warrant further investigation into these long-term changes. In this report we address the hypothesis that early life experience, such as a period of voluntary running in juvenile rats, can alter properties of adult neurogenesis for the remainder of the animal's life. The results indicate that the number of proliferating and differentiating neuronal precursors is not altered in runners beyond the initial weeks post-running, suggesting homeostatic regulation of these processes. However, the rate of neuronal maturation and survival during a 4 week period after cell division was enhanced up to 11 months of age (the end of the study period). This study is the first to show that a transient period of physical activity at a young age promotes changes in neurogenesis that persist over the long-term, which is important for our understanding of the modulation of neurogenesis by exercise with age. Functional integration of adult-born neurons within the hippocampus that resist homeostatic regulation with aging, rather than the absolute number of adult-born neurons, may be an essential feature of adult neurogenesis that promotes the maintenance of neural plasticity in old age.
Parsec-Scale Radio Structures in the Nuclei of Four Seyfert Galaxies

We present 18 cm radio maps of four Seyfert nuclei, Mrk 1, Mrk 3, Mrk 231, and Mrk 463E, made with the European VLBI Network (EVN). Linear radio structures are present in three out of four sources on scales of ~100 pc to ~1 kpc, and the 20 mas beam of the EVN enables us to resolve details within the radio structures on scales of less than 10 pc. Mrk 3 was also imaged using MERLIN, and the data were combined with the EVN data to improve the sensitivity to extended emission. We find an unresolved flat-spectrum core in Mrk 3, which we identify with the hidden Seyfert 1 nucleus in this object, and we also see marked differences between the two highly collimated radio jets emanating from the core. The western jet terminates in a bright hot spot and resembles an FR II radio structure, while the eastern jet has more in common with an FR I source. In the case of Mrk 463E, we use the radio and optical structure of the source to argue that the true nucleus lies approximately 1'' south of the position of the radio and optical brightness peaks, which probably represent a hot spot at the working surface of a radio jet. The EVN data also provide new evidence for a 100 pc radio jet powering the radio source in the Type 1 nucleus of Mrk 231. However, the Seyfert 2 galaxy Mrk 1 shows no evidence for radio jets down to the limits of resolution (~10 pc). We discuss the range of radio source size and morphology that can occur in the nuclei of Seyfert galaxies and the implications for Seyfert unification schemes and for radio surveys of large samples of objects.
Evasion of Innate Immune Responses by the Highly Virulent Cryptococcus gattii by Altering Capsule Glucuronoxylomannan Structure

Cryptococcus neoformans causes life-threatening diseases mainly in immunosuppressed hosts such as AIDS patients; C. gattii causes disseminated infections even in healthy hosts. To identify the possible molecular mechanisms underlying this difference in virulence, we investigated the survival and histopathology of lung tissue in wild-type and CD4-depleted mice infected with C. neoformans H99 and C. gattii JP02 (the highly virulent strain isolated in Japan); we then compared dendritic cell (DC) cytokine release responses to different cell fractions from these two strains. JP02-infected mice exhibited shorter survival and fewer inflammatory cells in the lung than H99-infected control mice. Depletion of CD4-related cellular immunity reduced survival of H99-infected mice but had no effect on the survival or inflammatory cell infiltration in JP02-infected mice, suggesting that JP02 evades immune detection. To identify the molecule(s) conferring this difference, we measured cytokine production from murine DCs co-cultured with H99 and JP02 in vitro. The levels of inflammatory cytokines from DCs treated with intact JP02 cells, the extracted capsule, secreted extracellular polysaccharides, and purified glucuronoxylomannan (GXM) were markedly lower than those induced by intact H99 cells and corresponding H99 fractions. Structural analysis of GXM indicated that JP02 altered one of two O-acetyl groups detected in the H99 GXM. Deacetylated GXM lost the ability to induce inflammatory cytokine release from DCs, implicating these O-acetyl groups in immune recognition. We conclude that the highly virulent C. gattii processes a structural alteration in GXM that allows this pathogen to evade the immune response and therefore elimination.
The Organization of Connections between Areas V5 and V1 in Macaque Monkey Visual Cortex

Area V5 or MT of primate extrastriate visual cortex is specialized for involvement in the analysis of motion and receives input from two layers, 4B and 6, of the striate cortex or V1. Injections of horseradish peroxidase ‐ wheatgerm agglutinin into V5 reveal a patchy distribution of labelled cells and axonal terminals in layer 4B, suggesting the presence of a segregated and functionally specialized subsystem within the layer. The patches are similar in size and frequency to the cytochrome oxidase blobs of layers 2 and 3, but bear little systematic relationship to them. V5‐efferent cells in layer 6, however, tend to avoid the cores of the blobs.
Making literacy policy and practice with a difference: generational change, professionalisation and literate futures

This article has been edited from a transcript of the keynote address to the combined ALEA/MTE National Conference, Hobart, Tasmania, August 2001. In this talk Allan reflects on some of the difficulties facing makers of literacy policy in 'New Times'. His reflections are informed by some important research that is having an impact· on literacy teaching in Australia and he raises various issues, ranging from what he sees as a 'dumbing down' of curriculum, to addressing the needs of'at risk' students, to issues of lifelong education in a rapidly changing world.
Shared Random Ferns for Efficient Detection of Multiple Categories

We propose a new algorithm for detecting multiple object categories that exploits the fact that different categories may share common features but with different geometric distributions. This yields an efficient detector which, in contrast to existing approaches, considerably reduces the computation cost at runtime, where the feature computation step is traditionally the most expensive. More specifically, at the learning stage we compute common features by applying the same Random Ferns over the Histograms of Oriented Gradients on the training images. We then apply a boosting step to build discriminative weak classifiers, and learn the specific geometric distribution of the Random Ferns for each class. At runtime, only a few Random Ferns have to be densely computed over each input image, and their geometric distribution allows performing the detection. The proposed method has been validated in public datasets achieving competitive detection results, which are comparable with state-of-the-art methods that use specific features per class.
Multifinality in the development of personality disorders: A Biology × Sex × Environment interaction model of antisocial and borderline traits

Abstract Although antisocial personality disorder (ASPD) is more common among males and borderline PD (BPD) is more common among females, some authors have suggested that the two disorders reflect multifinal outcomes of a single etiology. This assertion is based on several overlapping symptoms and features, including trait impulsivity, emotional lability, high rates of depression and suicide, and a high likelihood of childhood abuse and/or neglect. Furthermore, rates of ASPD are elevated in the first degree relatives of those with BPD, and concurrent comorbidity rates for the two disorders are high. In this article, we present a common model of antisocial and borderline personality development. We begin by reviewing issues and problems with diagnosing and studying PDs in children and adolescents. Next, we discuss dopaminergic and serotonergic mechanisms of trait impulsivity as predisposing vulnerabilities to ASPD and BPD. Finally, we extend shared risk models for ASPD and BPD by specifying genetic loci that may confer differential vulnerability to impulsive aggression and mood dysregulation among males and impulsive self-injury and mood dysregulation among females. Although the precise mechanisms of these sex-moderated genetic vulnerabilities remain poorly understood, they appear to interact with environmental risk factors including adverse rearing environments to potentiate the development of ASPD and BPD.
Supporting EFL learners with a Virtual Environment: A Focus on L2 Pronunciation

The article discusses a pilot project that explored the implementation of a virtual environment for the improvement of English pronunciation, funded by the Italian Ministry of Education, University and Research (MIUR) as part of a wider e-learning program for Higher Education. A speech recognition software program, SpeechAce, was embedded within the e-learning course to provide live practice and feedback on pronunciation to 372 undergraduate students at the University of Naples “L’Orientale” in 2016-2017. The project team was composed by Professors of English Oriana Palusci and Katherine E. Russo, who designed and coordinated the project, and e-tutors Jacqueline Aiello and Anna Mongibello, who generated the online course on Moodle and monitored students’ activities. The virtual class was created to foster awareness of English sounds and to practice pronunciation, an area that is often neglected in the Italian education system due to the large number of enrolled students. This paper first describes the project in depth and draws on the quantitative analysis of the students’ performance in combination with authentic online listening input. Then, data collected in pre- and post-program questionnaires are analyzed to examine the impact of participation in the online project on self-perceived pronunciation proficiency and L2 self-confidence, and to unveil participants’ opinions and experiences in this virtual environment.
Improved Stabilization Method for Lurie Networked Control Systems

The problem of stabilization of Lurie networked control systems (NCSs) is investigated in this paper. The network-induced delays in NCSs are assumed to be time-varying and bounded. By utilizing a reciprocally convex technique to consider the relationship between the network-induced delay and its varying interval, a new absolute stability condition is derived in terms of linear matrix inequalities (LMIs). Based on the obtained condition, an improved cone complementary linearisation (CCL) iteration algorithm is presented to design a state feedback controller. The effectiveness of the proposed method is verified by a numerical example.
FUSE Observations of U Geminorum during Outburst and Decline

We have obtained far-ultraviolet (904-1187 Å) spectra of U Gem in outburst with the Far Ultraviolet Spectroscopic Explorer. Three of the observations were acquired during the plateau phase of the outburst, while the fourth was obtained during late outburst decline. The plateau spectra have continuum shapes and fluxes that are approximated by steady state accretion disk model spectra with ≃ 7 × 10-9 M☉ yr-1. The spectra also show numerous absorption lines of H I, He II, and 2-5 times ionized transitions of C, N, O, P, S, and Si. There are no emission features in the spectra, with the possible exception of a weak feature on the red wing of the O VI doublet. The absorption lines are narrow (FWHM ~ 500 km s-1), too narrow to arise from the disk photosphere, and at low velocities (≤700 km s-1). The S VI and O VI doublets are optically thick. The absorption lines in the plateau spectra show orbital variability: in spectra obtained at orbital phases 0.53 ≤ Φ ≤ 0.79, low-ionization absorption lines appear and the central depths of the preexisting lines increase. The increase in line absorption occurs at the same orbital phases as previously observed EUV and X-ray light-curve dips. If the absorbing material is in (near-) Keplerian rotation around the disk, it must be located at large disk radii. The final observation occurred when U Gem was about 2 mag from optical quiescence. The spectra are dominated by emission from an ≃43,000 K, metal-enriched white dwarf (WD). The inferred radius of the WD is 4.95 × 108 cm, close to that observed in quiescence. Allowing for a hot heated region on the surface of the WD improves the fit to the spectrum at short (less than 960 Å) wavelengths.