Miracle-dz/UniFAR-FTUs huggingface dataset:
Evolution of multidrug-resistant Acinetobacter baumannii isolates obtained from elderly patients with respiratory tract infections.

OBJECTIVES To study the evolution between 1999 and 2002 and mechanisms of antibiotic resistance in a multidrug-resistant Acinetobacter baumannii clone predominant in isolates from elderly patients with respiratory tract infections. METHODS Susceptibility to antimicrobials was determined using an agar dilution method. Bacterial clones were identified by PCR-fingerprinting and PFGE with ApaI. Carbapenemases were detected by phenotypic tests; by PCR with primers specific for bla (OXA-40), bla(IMP), bla(VIM-1) and bla(VIM-2); and by hybridization with DNA probes. Class 1 integrons were detected using PCR. RESULTS In 1999 isolates were grouped into two main genotypes: clone I (33%) and clone II (55%). These were also detected in 2002 with a different distribution: clone I (69%), clone II (22%). Resistance to amikacin, meropenem and imipenem increased significantly in clone I over this time, whereas clone II was not affected. In 2002, the incidence of bla(OXA-40) rose to 91% in clone I isolates with some also harbouring bla(VIM-2) and bla(IMP) genes. Different class 1 integrons were detected ranging in size from 550 to 1200 bp. No relationship was found between carbapenemases and class 1 integrons. CONCLUSIONS In elderly patients, a single clone became predominant among A. baumannii isolates, coinciding with an increase in antibiotic resistance rates. The majority of isolates harboured the bla(OXA-40) carbapenemase gene and some of them also harboured bla(VIM-2) and bla(IMP) genes. The presence of class 1 integrons also increased over time.
Correlation Between Patatin-Like Phospholipase Domain-Containing Protein 3 Gene Polymorphisms and Liver Cirrhosis in a Chinese Han Population With Chronic Hepatitis B

Background: A single nucleotide polymorphism (SNP) of patatin-like phospholipase domain-containing 3 (PNPLA3) genes (rs738409) is associated with the severity of fibrosis and cirrhosis in patients with fatty liver disease. However, in a small group of Italian patients, there was no significant correlation between the rs738409 SNP and hepatitis B virus (HBV) infection-associated liver cirrhosis. Objectives: This study aimed to investigate whether PNPLA3 polymorphisms are a risk factor for liver cirrhosis in a Chinese Han population with chronic hepatitis B (CHB). Patients and Methods: The study population consisted of 344 Chinese Han patients with CHB, among which 203 presented with liver cirrhosis (LC group) and 141 had no sign of liver cirrhosis (CHB group). TaqMan genotyping assay was used to investigate the association of two PNPLA3 SNPs (rs738409 and rs2281135) with the risk of liver cirrhosis. Results: The allele and genotype distributions of PNPLA3 rs738409 and rs2281135 were not significantly different between the CHB and LC groups. After segregation on the basis of sex, no significant correlation between PNPLA3 (rs738409 and rs2281135) genotypes/alleles and liver cirrhosis was detected. Moreover, none of the haplotypes in PNPLA3 (rs738409 and rs2281135) was found to be statistically different between the two groups. Conclusions: Our results showed no association between PNPLA3 polymorphisms (rs738409 and rs2281135) and the susceptibility to HBV-related liver cirrhosis in a Chinese Han population.
Integration of instructional technology by university lecturers in secondary school teacher education programs in Zimbabwe: An exploratory study

INTEGRATION OF INSTRUCTIONAL TECHNOLOGY BY UNIVERSITY LECTURERS IN SECONDARY SCHOOL TEACHER EDUCATION PROGRAMS IN ZIMBABWE: AN EXPLORATORY STUDY by Rodwell Chitiyo In the context of continuous innovations in information and communication technology (ICT) and its impact on higher education, this descriptive study explores the state of instructional technology (IT) integration by university lecturers in pre-service secondary school teacher education programs in Zimbabwe. Specifically, the study examines how the lecturers conceptualize IT integration, how they integrate IT into their instruction, the support given by their institutions, and the constraints they face. The qualitative methodology used is basic or generic in nature (Merriam, 1998). Twenty-one lecturers in the colleges of education at 3 universities participated. The 3 data collection methods used are questionnaires, interviews and analysis of documents. Analysis of data was inductive and Miles and Huberman’s (1994) interactive data analysis model was employed. Findings show that the conceptualization of IT and its integration by the majority of the lecturers was largely as hardware in nature, with focus put on viewing technological tools as audiovisual aids. Lecturers with qualifications in educational technology (ET) viewed IT and its integration from what Schiffman (1995) calls a narrow systems view. Most of the lecturers used technological tools for illustrating key points in their lecture delivery and lecturers who used computers used these for lecture preparation. Lecturers’ computer proficiency and competencies were at the basic level in Internet usage, with little confidence shown in basic productivity software skills and in IT integration tasks and processes. The lecturers’ integration of IT was at the Entry and Adoption stages (Dwyer, Ringstaff and Sandholtz, 1991). Institutional support was characterized by poor availability and access to appropriate technological tools by both lecturers and students, and in the context of a hyper-inflationary operating environment, constraints ranged from lack of institutional funding, to the absence of an IT integration policy framework, and lack of appropriate initial and continuous staff development. This study is part of the genesis of instructional technology research in the Zimbabwean context. It is hoped that insights gleaned will influence policy, practice and future research. From a global perspective, this study will add to the limited knowledge and literature on instructional technology integration in “developing” and/or low-income countries like Zimbabwe. INTEGRATION OF INSTRUCTIONAL TECHNOLOGY BY UNIVERSITY LECTURERS IN SECONDARY SCHOOL TEACHER EDUCATION PROGRAMS IN ZIMBABWE: AN EXPLORATORY STUDY by Rodwell Chitiyo
Relationship Between Diffusion Tensor Imaging (DTI) Findings and Cognition Following Pediatric TBI: A Meta-Analytic Review

ABSTRACT This study meta-analyzed research examining relationships between diffusion tensor imaging and cognition following pediatric traumatic brain injury (TBI). Data from 14 studies that correlated fractional anisotropy (FA) or apparent diffusion coefficient/mean diffusivity with cognition were analyzed. Short-term (<4 weeks post-TBI) findings were inconsistent, but, in the medium to long term, FA values for numerous large white matter tracts and the whole brain were related to cognition. However, the analyses were limited by the diversity of brain regions and cognitive outcomes that have been examined; all in relatively small samples. Moreover, additional data are needed to investigate the impact of age and injury severity on these findings.
Smoking during Pregnancy Is Associated with a Decreased Incidence of Obstetric Anal Sphincter Injuries in Nulliparous Women

Background Smoking is a modifiable lifestyle factor that has been shown to be associated with adverse perinatal outcomes and to have adverse health and dose-dependent connective tissue effects. The objective of this study was to examine whether smoking during pregnancy was associated with the incidence of obstetric anal sphincter injuries (OASIS) among six birthweight groups in singleton vaginal deliveries, considering nulliparous and multiparous women separately between 1997 and 2007 in Finland. Methodology A retrospective population-based register study. Populations included women with spontaneous singleton vaginal deliveries, consisting of all 213,059 nulliparous and all 288,391 multiparous women. Incidence of OASIS (n = 2,787) between smoking status groups was adjusted using logistic regression analyses. Principal Findings Of the nulliparous women, 13.1% were smokers, 3.6% had given up smoking during the first trimester of their pregnancy and 81.1% were non-smokers. Among these groups 0.7%, 0.9% and 1.1%, respectively suffered OASIS (p≤0.001). Nulliparous women who smoked had a 28% (95% CI 16–38%, p≤0.001) lower risk of OASIS compared to non-smokers, when adjusting for background variables. In multiparous women, the overall frequencies of OASIS were much lower (0.0–0.2%). A similar inverse relationship between OASIS rates and smoking was significant in pooled univariate analysis of multiparous women, but multivariate analysis revealed statistically insignificant results between non-smokers and smokers. Conclusions Nulliparous women who were smokers had a 28% lower incidence of OASIS. However, smoking during pregnancy cannot be recommended since it has shown to be associated with other adverse pregnancy outcomes and adverse health effects. The observed association warrants clinical repetition studies and, if confirmed, also in vitro studies focusing on connective tissue properties at a molecular and cellular level.
Input-Output Connections between Sectors and Optimal Monetary Policy

This paper considers the monetary policy implications of a model that features input-output connections between stages of production, so that a distinction between CPI inflation and PPI inflation arises. More specifically, this paper addresses the policy conclusion by K. Huang and Z. Liu [2005, "Inflation targeting: What inflation rate to target", Journal of Monetary Economics 52], which states that central banks should use an optimal inflation index that gives substantial weight to stabilising both CPI and PPI. This paper argues that these authors' findings rely on the assumption that producer prices are as sticky as consumer prices and it also shows that, once empirically relevant frequencies of price adjustment are used to calibrate the model, CPI inflation receives substantial weight in the optimal inflation index. Moreover, this rule is remarkably robust to uncertainty regarding the model parameters, whereas the policy rule proposed by Huang and Liu can result in heavy welfare losses.
Materiality and Organizing: Social Interaction in a Technological World

Ask a person on the street whether new technologies bring about important social change and you are likely to hear a resounding "yes. " But the answer is less definitive amongst academics who study technology and social practice. Scholarly writing has been heavily influenced by the ideology of technological determinism - the belief that some types or technologically driven social changes are inevitable and cannot be stopped. Rather than argue for or against notions of determinism, the authors in this book ask how the materiality (the arrangement of physical, digital, or rhetorical materials into particular forms that endure across differences in place and time) of technologies, ranging from computer-simulation tools and social media, to ranking devices and rumours, is actually implicated in the process of formal and informal organizing. The book builds a new theoretical framework to consider the important socio-technical changes confronting people's everyday experiences in and outside of work. Leading scholars in the field contribute original chapters examining the complex interactions between technology and the social, between artefact and humans. The discussion spans multiple disciplines, including management, information systems, informatics, communication, sociology, and the history of technology, and opens up a new area of research regarding the relationship between materiality and organizing.
Effects of a Twelve-Week Weight Reduction Exercise Programme on Selected Spatiotemporal Gait Parameters of Obese Individuals

Objectives. This study was carried out to investigate the effects of twelve-week weight reduction exercises on selected spatiotemporal gait parameters of obese individuals and compare with their normal weight counterparts. Methods. Sixty participants (30 obese and 30 of normal weight) started but only 58 participants (obese = 30, normal weight = 28) completed the quasi-experimental study. Only obese group had 12 weeks of weight reduction exercise training but both groups had their walking speed (WS), cadence (CD), step length (SL), step width (SW), and stride length (SDL) measured at baseline and at the end of weeks 4, 8, and 12 of the study. Data were analysed using appropriate descriptive and inferential statistics. Results. There was significantly lower WS, SL, and SDL but higher CD and SW in obese group than the normal weight group at baseline and week 12. However, the obese group had significantly higher percentage changes in all selected spatiotemporal parameters than the normal weight group. Conclusion. The 12-week weight reduction exercise programme produced significantly higher percentage changes in all selected spatiotemporal gait parameters in the obese than normal weight individuals and is recommended for improvement of these parameters among the obese individuals with gait related problems.
Towards a simplification of the bug report form in eclipse

We believe that the bug report form of Eclipse contains too many fields, and that for some fields, there are too many options. In this MSR challenge report, we focus in the case of the severity field. That field contains seven different levels of severity. Some of them seem very similar, and it is hard to distinguish among them. Users assign severity, and developers give priority to the reports depending on their severity. However, if users can not distinguish well among the various severity options, they will probably assign different priorities to bugs that require the same priority. We study the mean time to close bugs reported in Eclipse, and how the severity assigned by users affects this time. The results shows that classifying by time to close, there are less clusters of bugs than levels of severity. We therefore conclude that there is a need to make a simpler bug report form.
Location Patterns of Services in France: A Distance-Based Approach ✩

We study the location patterns of business-oriented services and manufacturing industries in France. We develop a new test of localization considering space as continuous. Our test relies on a measure of divergence in the space of density distribu tions that allows us to assess whether or not the density distribution of bilateral distance s between all pairs of plants within an industry significantly departs from randomness. We improve the test proposed by Duranton and Overman (2005), which proves to be biased with respect to the number of plants in the industry under scrutiny. Our test doe s not suffer from such a bias. This property is crucial for the French case where industrial concentrations of service and manufacturing industries drastically differ. With this distance-based method, we highlight some distinctive locational features of services not mentioned in the literature so far. We put forward that: 1/ service industries diverge more often from randomness than manufacturing industries, 2/ a majority of diverging service industries are localized at very short distances (before 4 km) whereas a majority of manufacturing industries are localized at longer distances or even dispersed, 3/ within a majority of service industries, the largest plants appear localized at short distances in c omparison with other plants, 4/ within most service industries, new plants reduce localization whereas exiters reinforce it over the period 1996-2005.
Solar-like oscillations with low amplitude in the CoRoT target HD 181906

Context. The F8 star HD 181906 (effective temperature ∼6300 K) was observed for 156 days by the CoRoT satellite during the first long run in the direction of the galactic centre. Analysis of the data reveals a spectrum of solar-like acoustic oscillations. However, the faintness of the target (mv = 7.65) means the signal-to-noise (S/N) in the acoustic modes is quite low, and this low S/N leads to complications in the analysis. Aims. We extract global variables of the star, as well as key parameters of the p modes observed in the power spectrum of the lightcurve. Methods. The power spectrum of the lightcurve, a wavelet transform and spot fitting were used to obtain the average rotation rate of the star and its inclination angle. Then, the autocorrelation of the power spectrum and the power spectrum of the power spectrum were used to properly determine the large separation. Finally, estimations of the mode parameters were done by maximizing the likelihood of a global fit, where several modes were fit simultaneously. Results. We have been able to infer the mean surface rotation rate of the star (∼4 μHz) with indications of the presence of surface differential rotation, the large separation of the p modes (∼87 μHz), hence also the “ridges” corresponding to overtones of the acoustic modes.
Hematological Profile and Martial Status in Rugby Players during Whole Body Cryostimulation

Cold-based therapies are commonly applied to alleviate pain symptoms secondary to inflammatory diseases, but also to treat injuries or overuse, as done in sports rehabilitation. Whole body cryotherapy, a relatively new form of cold therapy, consists of short whole-body exposure to extremely cold air (−110°C to −140°C). Cryostimulation is gaining wider acceptance as an effective part of physical therapy to accelerate muscle recovery in rugby players. The aim of this study was to evaluate the effect of repeated cryostimulation sessions on the hematological profile and martial status markers in professional rugby players. Twenty-seven professional rugby players received 2 daily cryostimulation treatments for 7 consecutive days. Blood samples were collected before and after administration of the cryotherapic protocol and hematological profiles were obtained. No changes in the leukocyte count or composition were seen. There was a decrease in the values for erythrocytes, hematocrit, hemoglobin and mean corpuscular hemoglobin content, and an increase in mean corpuscular volume and red cell distribution width. Platelet count and mean volume remained unchanged. Serum transferrin and ferritin decreased, while soluble transferrin receptor increased. Serum iron and transferrin saturation were unchanged, as was reticulocyte count, whereas the immature reticulocyte fraction decreased substantially. In conclusion, in this sample of professional rugby players, cryostimulation modified the hematological profile, with a reduction in erythrocyte count and hemoglobinization paralleled by a change in martial status markers.
Correlation Based Vergence Control Using Log-polar Images ?

This paper describes a real-time vergence control mechanism based on log-polar images, developed for a robot head. We show that vergence behavior can be achieved at reduced computational cost using simple correlation measures on log-polar images. The main advantages of using a non-uniform image sampling mechanism, such as the log-polar images, are related both to perceptual and algorithm complexity issues. We show that, when using correlation measures to control vergence, log-polar images give better results than cartesian images. Additionally, as log-polar images are smaller, the computation time is reduced. Two algorithms for closed loop vergence control, using correlation measures over log-polar images, are proposed and compared. Their behavior in real situations is illustrated by test examples.
Enriching SMT Training Data via Paraphrasing

This paper proposes a novel method to resolve the coverage problem of SMT system. The method generates paraphrases for source-side sentences of the bilingual parallel data, which are then paired with the target-side sentences to generate new parallel data. Within a statistical paraphrase generation framework, we employ an object function, named Sentence Novelty, to select paraphrases which having the most novel information to the bilingual training corpus of the SMT model. Meanwhile, the context is considered via a language model in the source language to ensure the fluency and accuracy of paraphrase substitution. Compared to a state-of-the-art phrase based SMT system (Moses), our method achieves an improvement of 1.66 points in terms of BLEU on a small training corpus which simulates a resource-poor environment, and 1.06 points on a training corpus of medium size.
Incidence of Non-Traumatic Subconjunctival Hemorrhage in a Nationwide Study in Taiwan from 2000 to 2011

Objective To determine the nationwide incidence of non-traumatic subconjunctival hemorrhage (NTSCH) in Taiwan from 2000-2011 and to analyze the risk factors for NTSCH using a case-control analysis. Methods This is a population-based cohort administrative database study. Randomly selected 1,000,000 residents from the Taiwan National Health Insurance Research Database in 2000 and followed for 12 years to determine the population incidence of NTSCH. Individuals with the first diagnosis of subconjunctival hemorrhage were identified by the corresponding International Classification of Diseases code (ICD) 372.72. Traumatic subconjunctival hemorrhages (ICD-9 codes 921, 871, 850-854 and 959.01) were excluded. The association of NTSCH with various demographic factors, comorbidities and use of medications was studied by a population based case-control analysis using data of 2008-2011. Results A total of 67,720 patients with a first-time diagnosis of NTSCH were identified during the 12 years period. The mean annual incidence was 65 per 10,000 individuals (crude incidence) and 60 per 10,000 individuals (age- and sex-standardized incidence). The incidence rate of NTSCH was higher in women than in men, [men-women ratio: 0.80 (95% confidence interval: 0.78-0.81)]. The age-specific incidence decreased from childhood to the group of teenagers, after which it increased to a maximal value of 136.2 per 10,000 people in the age group of 60-69 years. Case-control analysis showed that comorbidities of hypertension, purpura and thrombocytopenia, and the use of aspirin were significantly associated with the risk of NTSCH. Conclusions This study indicates that NTSCH is a common eye disease that occurs once in 167 individuals in a general East Asian population per year. It occurs more often in women than in men and the age-specific incidence peaked in the age group of 60-69 years. Hypertension, purpura and thrombocytopenia, and the use of aspirin are the major risk factors for NTSCH.