Miracle-dz/UniFAR-FTUs huggingface dataset:
Training RNNs as Fast as CNNs

Common recurrent neural network architectures scale poorly due to the intrinsic difficulty in parallelizing their state computations. In this work, we propose the Simple Recurrent Unit (SRU) architecture, a recurrent unit that simplifies the computation and exposes more parallelism. In SRU, the majority of computation for each step is independent of the recurrence and can be easily parallelized. SRU is as fast as a convolutional layer and 5-10x faster than an optimized LSTM implementation. We study SRUs on a wide range of applications, including classification, question answering, language modeling, translation and speech recognition. Our experiments demonstrate the effectiveness of SRU and the trade-off it enables between speed and performance. We open source our implementation in PyTorch and CNTK.
Citizen Science as a New Tool in Dog Cognition Research

Family dogs and dog owners offer a potentially powerful way to conduct citizen science to answer questions about animal behavior that are difficult to answer with more conventional approaches. Here we evaluate the quality of the first data on dog cognition collected by citizen scientists using the Dognition.com website. We conducted analyses to understand if data generated by over 500 citizen scientists replicates internally and in comparison to previously published findings. Half of participants participated for free while the other half paid for access. The website provided each participant a temperament questionnaire and instructions on how to conduct a series of ten cognitive tests. Participation required internet access, a dog and some common household items. Participants could record their responses on any PC, tablet or smartphone from anywhere in the world and data were retained on servers. Results from citizen scientists and their dogs replicated a number of previously described phenomena from conventional lab-based research. There was little evidence that citizen scientists manipulated their results. To illustrate the potential uses of relatively large samples of citizen science data, we then used factor analysis to examine individual differences across the cognitive tasks. The data were best explained by multiple factors in support of the hypothesis that nonhumans, including dogs, can evolve multiple cognitive domains that vary independently. This analysis suggests that in the future, citizen scientists will generate useful datasets that test hypotheses and answer questions as a complement to conventional laboratory techniques used to study dog psychology.
Impact of LMP7 (rs2071543) gene polymorphism in increasing cancer risk: evidence from a meta-analysis and trial sequential analysis

Genetic variant LMP7 (low molecular weight polypeptide 7) –145 C > A may influence the function of immune surveillance of an individual and lead to cancer development. Various studies have investigated the relevance of LMP7 –145 C > A gene polymorphism with cancer risk; but, their results are conflicting and inconsistent. To obtain a comprehensive conclusion, a meta-analysis was performed by including eight eligible published studies retrieved from PubMed (Medline), EMBASE and Google Scholar web search until December 2016. Individuals with AA genotype (AA vs CC: p = 0.001; OR = 2.602, 95% CI = 1.780 to 3.803) of LMP7 -145 C > A were found to have 2 folds higher risk of cancer than those with CC genotype. The recessive genetic model (AA vs AC + CC) also indicated that individuals with AA genotype have 2 folds higher cancer risk than AC and CC genotypes (p = 0.001; OR = 2.216, 95% CI = 1.525 to 3.221). Also, significant increased cancer risk was observed in Asians but not in Caucasians. No publication bias was observed during the analysis. Trial sequential analysis also strengthened our current findings. These results suggest that genetic variant LMP7–145 C > A has significant role in increasing cancer risk in overall and Asian population, and could be useful as a prognostic marker for early cancer predisposition.
Reasons behind providing futile medical treatments in Iran

Background: Despite their negative consequences, evidence shows that futile medical treatments are still being provided, particularly to terminally ill patients. Uncovering the reasons behind providing such treatments in different religious and sociocultural contexts can create a better understanding of medical futility and help manage it effectively. Research objectives: This study was undertaken to explore Iranian nurses’ and physicians’ perceptions of the reasons behind providing futile medical treatments. Research design: This was a qualitative exploratory study. Study data were gathered through conducting in-depth semi-structured personal interviews and analyzed using the conventional content analysis method. Participants and research context: Twenty-one nurses and nine medical specialists were recruited purposively from four teaching hospitals affiliated to Tehran University of Medical Sciences. Ethical considerations: This study was approved by the Nursing and Midwifery Research Center and the Research Ethics Committee of Tehran University of Medical Sciences. All participants gave informed consent for the research and that their anonymity was preserved. Findings: The main theme of the study was “having an obligation to provide medical treatments despite knowing their futility. ” This theme consisted of three main categories including patients’ and family members’ request for continuing life-sustaining treatments, healthcare professionals’ personal motives, and organizational atmosphere and structure. Discussion and conclusion: Different personal and organizational factors contribute to providing futile medical treatments. Promoting the structure and the function of hospital ethics committees, establishing and developing home care facilities, increasing the number of palliative care centers and hospices, and educating healthcare professionals, patients, and family members about the services and the benefits of such centers can facilitate making wise decisions about continuing or discontinuing treatments which have been labeled as futile.
An Efficient Temporally-Constrained Probabilistic Model for Multiple-Instrument Music Transcription

In this paper, an efﬁcient, general-purpose model for multiple instrument polyphonic music transcription is proposed. The model is based on probabilistic latent component analysis and supports the use of sound state spectral templates, which represent the temporal evolution of each note (e.g. attack, sustain, decay). As input, a variable-Q transform (VQT) time-frequency representation is used. Computational efﬁciency is achieved by supporting the use of pre-extracted and pre-shifted sound state templates. Two variants are presented: without temporal constraints and with hidden Markov model-based constraints controlling the appearance of sound states. Experiments are performed on benchmark transcription datasets: MAPS, TRIOS, MIREX multiF0, and Bach10; results on multi-pitch detection and instrument assignment show that the proposed models out-perform the state-of-the-art for multiple-instrument transcription and is more than 20 times faster compared to a previous sound state-based model. We ﬁnally show that a VQT representation can lead to improved multi-pitch detection performance compared with constant-Q representations.
Cardiac abnormalities in severe acute dichlorvos poisoning*

Objective:Patients with organophosphorus poisoning sometimes die suddenly during rigorous treatment, possibly from myocardial injury. This study sought to elucidate the mechanisms underlying organophosphorus poisoning-induced cardiotoxicity. Design:Prospective observational study. Setting:Urban, tertiary teaching hospital emergency intensive care unit with 10 beds. Patients:Forty-one patients with severe acute dichlorvos poisoning were consecutively enrolled (n = 92) at emergency intensive care unit and followed for 3 months. Measurements and Main Results:Levels of serum creatine kinase isoenzyme myocardium, cardiac troponin I, acetylcholinesterase, acetylcholine, epinephrine, and norepinephrine were tested on hospital days 1, 3, and 5 and on discharge day. Electrocardiography was recorded on admission and then every other day. Transthoracic echocardiography was performed at admission, in the acute phase, before discharge, and during follow-up. Technetium 99m-sestamibi myocardial single photon emission computed tomography was conducted in four patients. Thirty-seven (90.2%) patients survived and four (9.8%) patients died during treatment. We observed sinus tachycardia in 37 (90.2%) patients and ST-T changes in 33 (80.4%) patients. Creatine kinase isoenzyme myocardium and cardiac troponin I levels peaked at day 3 postadmission and then decreased to normal levels. Serum acetylcholine, epinephrine, and norepinephrine peaked at day 1 after admission and then decreased. Echocardiography revealed marked decreases in wall motion of the interventricular septum and left ventricle in the acute phase but returned to normal in the recovery phase. The left ventricular ejection fraction improved significantly from 42 ± 5% to 59 ± 4% (p = .001). Single photon emission computed tomography showed abnormal left ventricle perfusion. Conclusion:Severe acute dichlorvos poisoning is associated with reversible myocardial dysfunction, possibly through an increase in catecholamine levels.
African departure rather than migration speed determines variation in spring arrival in pied flycatchers

Properly timed spring migration enhances reproduction and survival. Climate change requires organisms to respond to changes such as advanced spring phenology. Pied flycatchers Ficedula hypoleuca have become a model species to study such phenological adaptations of long-distance migratory songbirds to climate change, but data on individuals' time schedules outside the breeding season are still lacking. Using light-level geolocators, we studied variation in migration schedules across the year in a pied flycatcher population in the Netherlands, which sheds light on the ability for individual adjustments in spring arrival timing to track environmental changes at their breeding grounds. We show that variation in arrival dates to breeding sites in 2014 was caused by variation in departure date from sub-Saharan Africa and not by environmental conditions encountered en route. Spring migration duration was short for all individuals, on average 2 weeks. Males migrated ahead of females in spring, while migration schedules in autumn were flexibly adjusted according to breeding duties. Individuals were therefore not consistently early or late throughout the year. In fast migrants like our Dutch pied flycatchers, advancement of arrival to climate change likely requires changes in spring departure dates. Adaptation for earlier arrival may be slowed down by harsh circumstances in winter, or years with high costs associated with early migration.
Performance evaluation of MACACO: a multilayer Compton camera

Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a 22Na and an 88Y radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a 22Na source at a distance of 5 cm.
An Exploration of the Factors that Influence the Successful Implementation of the World Health Organization Surgical Safety Checklist

This study presents an exploration of the factors which influence the successful implementation of the WHO Surgical Safety Checklist. A mixed methodological approach using a questionnaire was sent to 348 healthcare professionals in a single NHS trust who use the WHO checklist. 103 questionnaires were returned; five were incomplete and discarded. Data was analysed from 98 questionnaires. Results were evaluated alongside recommendations from a previous audit that took place in this trust in 2013. 63% of surgeons and 54% of anaesthetists within the trust remain untrained as regards the surgical safety checklist. Sign out was the poorest performing component; time out also needed improvement. The biggest obstacle in successful implementation was found to be disengagement of the surgical team. Simulation and team training can enhance non-technical skills, improving communication between staff. The study concludes that differing staff perceptions were found to create barriers to successful implementation of the checklist. Training of all staff is necessary for effective communication within the operating theatre.
Does psychotherapy for young adults in routine practice show similar results as therapy in randomized clinical trials?

Abstract Previous research indicates that patients treated with psychotherapy in the community do not stay in treatment long enough to achieve clinically significant change. Because the average patient seeking treatment at a community center may not be as informed and motivated for change as the average patient participating in a research trial, the authors compared outcome among all patients presenting to a mental health clinic (n=416) and a subgroup of patients who started psychotherapy at the same clinic (n=101). Outcome was assessing using the Symptom Checklist-90, Inventory of Interpersonal Problems, and Global Assessment of Functioning. Results confirmed that outcome among all patients seeking the centre was worse than in an average clinical trial. However, patients who started psychotherapy after assessment achieved results comparable to those in RCT studies.
Enterprise systems implementation and accounting benefits

Purpose – The aim of this paper is to examine the accounting benefits involved in adopting enterprise systems, but also to comprehend the underlying causes that motivate their adoption.Design/methodology/approach – This paper presents evidence from a survey of 73 companies which implemented ES on the related benefits to their accounting information provision and practices.Findings – Empirical evidence confirms a number of benefits derived from the application of ES that focus on the following dimensions: organisation, operations, management and IT infrastructure. These benefits are related both to the reasons leading to the implementation of ES and to the relevant selection of ES modules.Originality/value – The corresponding results from this survey can then be used as a basis for establishing the best approach in order to fully exploit the potential of future ES applications in accounting practice.
Study of internal transcribed spacer and mitochondrial large-subunit genes of Pneumocystis carinii hominis isolated by repeated bronchoalveolar lavage from human immunodeficiency virus-infected patients during one or several episodes of pneumonia

The objective of this study was to type, analyze, and compare Pneumocystis carinii hominis strains obtained from different samples during a given or recurrent episodes of P. carinii pneumonia (PCP) for epidemiologic purposes. We studied 36 bronchoalveolar lavage (BAL) or induced sputum (IS) samples from 16 human immunodeficiency virus-infected patients with one or several episodes of PCP. PCR amplification and direct sequencing were performed on the two internal transcribed spacers (ITS1 and ITS2) of P. carinii hominis rRNA genes by using DNA extracted from BAL or IS samples, and the sequences were compared to the mitochondrial large-subunit (mt LSU) gene sequence determined in a previous study in our laboratory. The studies of the mt LSU and ITS sequences showed that some patients (n = 10) were infected with the same strains of P. carinii hominis during a given episode of PCP. In one patient infected with strains with identical sequences in several episodes, the recurrence could have been due to reactivation of organisms not eliminated by treatment during the first episode or to de novo infection by an identical strain. In five patients infected with strains with different sequences in each episode, recurrence was due to de novo infection. Sequence analysis of these two P. carinii hominis gene regions showed that de novo infection can occur in AIDS patients with recurrent PCP.
On Measuring the Welfare Gains from Trade Under Consumer Heterogeneity

I develop a multi‐country, multi‐industry model of trade that features heterogeneous consumers with non‐homothetic preferences. I use the model to quantify the measurement errors in the welfare gains estimates caused by the assumption of a representative consumer (ARC). First, I reduce the world level of all trade costs by 15% and find that ARC overestimates (underestimates) the gains of the poor (rich) by up to 5 (11) percentage points. Second, I eliminate import tariffs around the globe and show that the loss of tariff revenues is not negligible for some consumers and that the measurement errors from ARC are between −15 and 4% points.
New conditions for stability and stabilizaion of Takagi-Sugeno fuzzy systems

The paper discusses the stability and stabilization of nonlinear systems based on Takagi-Sugeno models, which are a well-known system that can represent a wide class of nonlinear systems. Due to the importance of the models, many results on the stability problem have been in the literature and they have shown their progressive methods. However, there is still room to reduce the conservativeness of the existing stability conditions. In this paper, new stability conditions and control design methods are proposed. To this end, a new Lyapunov function, which has an integral structure of the membership function, is introduced. This structural Lyapunov function eventually reduces the conservatism in stability and stabilizability conditions. On top of that, descriptor system approach and generalized relaxation lemma are employed to further reduce the conservatism. Finally, an illustrative example is given to show the effectiveness of our control design methods.
Survey of prevalence and investigation of predictors and staining patterns of the split upper eyelid defect in Hebridean sheep

The split upper eyelid defect (SUED) is a congenital defect of the upper eyelid thought to be exclusive to multihorned sheep. Eleven flocks with a high proportion of multihorned Hebridean sheep were visited in 2011. Statistical analysis was performed generating Pearson's chi-squared analysis, as well as (1) logistic regression, (2) ordinal logistic regression and (3) linear regression models. Four hundred and seventy-three pure-bred Hebridean sheep and one crossbred lamb were examined. Of all the multihorned animals inspected in 2011, 9.7 per cent of adults had evidence of SUED in one or more eyelids, with 17.6 per cent of lambs presented with one or more eyelid affected. Having five or more horns was protective in the linear regression model on eye-level data (p=0.045). Forward-facing horns were consistently associated with a ‘worst’ eye score in the eye-level data, with an odds ratio (OR) as high as 9.4 when compared with a base of backward-facing horns (p=0.002). Eyes positive for SUED were significantly more likely to be rose bengal stain-positive in all four analysis, including multilevel mixed effect ordered logistic regression (p<0.001, OR 149.3). A novel lesion was identified during the course of the study, with 3.4 per cent of lambs presented with dermoid. SUED was also identified in a crossbred animal. Further work is needed to quantify the exact cost to animals with unilateral or bilateral SUED with subtle and production cost of SUED.
Evaluation of adipokines in children with cystic fibrosis.

INTRODUCTION Patients with CF present numerous pathological conditions such as malnutrition, depletion of fat-free mass, metabolic disturbances (abnormal glucose metabolism, increased insulin resistance, chronic energy deficit, local and chronic inflammation), which could affect or be associated with altered adipokines concentration Material and Methods: We aimed in this study to investigate the levels of selected adipokines such as resistin, apelin, adiponectin to demonstrate their application as possible markers of inflammation. RESULTS Serum level of resistin was higher (p < 0.001) and adiponectin - lower (p=0.02) in CF children than in healthy children. There was no difference in serum apelin level between two examined groups. However, values of adiponectin/BMI and apelin/BMI ratios in CF did not differ significantly from controls. Higher values of resistin/BMI ratio in CF in comparison to controls were observed Serum resistin/adiponectin ratio was significantly higher in CF patients than in controls (p < 0.0001). Resistin/BMI ratio correlated negatively with FEV1 (R:-48,p < 0.043). Serum resistin/adiponectin ratio correlated negatively with FEV1/FVC (R:-49, p=0.04), Adipokines showed no correlation with BMI and BMI-SDS, glucose, total cholesterol, and LDL-, HDL-cholesterol, triglyceride serum levels. Spirometric parameters FEV1, FVC, VC correlated negatively with serum glucose levels (R: -0.55, p < 0.018; R: -0.65 p < 0.0025; R:-0.76, p < 0.0008 respectively). FEV1 and FVC correlated positively with BMI-SDS (R:0.58, p < 0.01; R:0.5, p < 0.036, respectively). CONCLUSIONS A significant increase in resistin concentration expressed also as resistin/BMI, and resistin/adiponectin ratios, observed in children with CF may suggests that this adipokine is involved in the inflammatory process underlying the disease and is related to worse spirometric parameters describing airways obstruction.
Student Voice: Embracing Student Activism as a Quality Improvement Tool in Higher Education

This chapter illustrates how student activism, taken in the context of the student voice, can be harnessed as a way of enhancing the quality of educational provision in higher education. Agenda 2063 of the African Commission recognizes equitable access to quality higher education as critical for national development. In the face of an increase in stu‐ dent protests and the resultant destruction of infrastructure and human life, it becomes imperative to find ways of creating positive and innovative teaching and learning envi ‐ ronments that take full advantage of student activism. The chapter draws on existing literature on student activism and the value of student voice to inform the development of a model for incorporating the “student voice” as a way of harnessing the positive aspects of student activism.
Fractional-order observer for integer-order LTI systems

We devise an observer for integer-order LTI systems resorting to a fractional-order estimation error dynamics. For this purpose, we derive a class of fractional-order systems associated with the original integer-order LTI system and present necessary and sufficient conditions for their observability and controllability. These systems serve to compare the integer-order with the fractional-order dynamics by means of eigenvalue locations. As a result, we obtain an observer that shows a very fast convergence immediately after initialization. The algebraic decay of fractional-order systems results in a rather poor convergence of the estimation for large times. To overcome this, we propose two strategies: (i) We reinitialize the observer in short intervals such that the observer converges faster and (ii) we propose a fractional-order impulsive observer which yields the exact state in fixed time.