Miracle-dz/UniFAR-FTUs huggingface dataset:
Planning for green cloud data centers using sustainable energy

The high power consumption of cloud data centers has aroused great concern on environmental implications such as global warming. Therefore, cloud service providers like Facebook and Green House Data have built their own wind or solar farms to power the data centers to reduce both energy cost and carbon emissions. In this paper, we propose an optimization- based framework to make planing for green cloud data centers, where the objective functions range from minimizing energy cost to minimizing carbon emissions. Our planning is based on the optimized scheduling of the users' requests to each data center, while considering time-varying and location-varying electricity prices and the supply of sustainable energy under different weather conditions. Our plan includes: 1) How many servers each data center should have. 2) How many wind turbines and solar panels should be used to power each data center. 3) What capacity of energy storage device (ESD) should be equipped for each data center. We formulate each problem as a constraint optimization problem, and solve it using Cplex. Extensive experiments have been done on traces from real world. As far as we know, our work is the first to explore the issue of planning for green cloud data centers through optimized scheduling methods.
Potential Toxicity of &agr;-Cypermethrin-Treated Nets on Tuta absoluta (Lepidoptera: Gelechiidae)

ABSTRACT Insect-proof nets are thought to be effective physical barriers to protect tomato crops against several insect pests, including the invasive tomato pest, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae). However, protected tomato crops are frequently infested by this destructive pest, and there is a higher infestation of plants closer to openings in Mediterranean greenhouses, suggesting that immigrating adults can easily walk on these protective materials and find a way to reach the crop. Laboratory bioassays were carried out to characterize the potential toxicity of &agr;-cypermethrin-treated insect-proof nets (Agronet) against T. absoluta adults. The data showed that the net acts mainly through a variety of chronic sublethal effects rather than acute ones. Reduced longevity and, more markedly, a reduced number of laid eggs were observed after the moths were exposed to the treated net over the duration of their lifetimes. A Y-tube experiment showed that the treated net does not affect the T. absoluta olfaction cues for host location. In contrast, when the moths were given the option to choose either the treated or the untreated net in laboratory cages, they significantly preferred the untreated one. The toxicological significance and the functional implications of these subtle effects for the implementation of integrated T. absoluta management strategies are discussed.
Coralline algae (Rhodophyta) in a changing world: integrating ecological, physiological, and geochemical responses to global change

Coralline algae are globally distributed benthic primary producers that secrete calcium carbonate skeletons. In the context of ocean acidification, they have received much recent attention due to the potential vulnerability of their high‐Mg calcite skeletons and their many important ecological roles. Herein, we summarize what is known about coralline algal ecology and physiology, providing context to understand their responses to global climate change. We review the impacts of these changes, including ocean acidification, rising temperatures, and pollution, on coralline algal growth and calcification. We also assess the ongoing use of coralline algae as marine climate proxies via calibration of skeletal morphology and geochemistry to environmental conditions. Finally, we indicate critical gaps in our understanding of coralline algal calcification and physiology and highlight key areas for future research. These include analytical areas that recently have become more accessible, such as resolving phylogenetic relationships at all taxonomic ranks, elucidating the genes regulating algal photosynthesis and calcification, and calibrating skeletal geochemical metrics, as well as research directions that are broadly applicable to global change ecology, such as the importance of community‐scale and long‐term experiments in stress response.
Using Linked Disambiguated Distributional Networks for Word Sense Disambiguation

We introduce a new method for unsupervised knowledge-based word sense disambiguation (WSD) based on a resource that links two types of sense-aware lexical networks: one is induced from a corpus using distributional semantics, the other is manually constructed. The combination of two networks reduces the sparsity of sense representations used for WSD. We evaluate these enriched representations within two lexical sample sense disambiguation benchmarks. Our results indicate that (1) features extracted from the corpus-based resource help to significantly outperform a model based solely on the lexical resource; (2) our method achieves results comparable or better to four state-of-the-art unsupervised knowledge-based WSD systems including three hybrid systems that also rely on text corpora. In contrast to these hybrid methods, our approach does not require access to web search engines, texts mapped to a sense inventory, or machine translation systems.
Effect of thyroxine on the isolated rat intestine

EDITORIAL SYNOPSIS In the intact animal some observers have shown an increased absorption of sugars and fatty acid after treatment with thyroxin. The following paper, in which uptake studies on the small isolated intestine of rats made thyrotoxic are reported, shows that inhibition of absorption of water, glucose, and a non-utilizable amino-acid (ac-amino isobutyric acid) can also result. The authors feel that the estimation for these differences may be because of differences of doses of thyroxine, methods of administration, and possibly a variable effect of different tissues.
Association between expression of the H histo-blood group antigen , α 1 , 2 fucosyltransferases polymorphism of wild rabbits , and sensitivity to rabbit hemorrhagic disease virus

RHDV (rabbit hemorrhagic disease virus) is a highly virulent calicivirus that has become a major cause of mortality in wild rabbit populations (Oryctolagus cuniculus). It binds to the histo-blood group antigen (HBGA) H type 2 which requires an α1,2fucosyltransferase for its synthesis. In rabbit, three α1,2fucosyltransferases genes are known, Fut1, Fut2, and Sec1. Nonfunctional alleles at any of these loci could potentially confer resistance to RHDV, similar to human FUT2 alleles that determine the nonsecretor phenotype and resistance to infection by various NoV strains. In this study, we looked for the presence of H type 2 on buccal epithelial cells of wild rabbits from two geographic areas under RHDV pressure and from one RHDV-free area. Some animals with diminished H type 2 expression were found in the three populations (nonsecretor-like phenotype). Their frequency markedly increased according to the RHDV impact, suggesting that outbreaks selected survivors with low expression of the virus ligand. Polymorphisms of the Fut1, Fut2, and Sec1 coding regions were determined among animals that either died or survived outbreaks. The Fut2 and Sec1 genes presented a high polymorphism and the frequency of one Sec1 allele was significantly elevated, over 6fold, among survivors. Sec1 enzyme variants showed either moderate, low, or undetectable catalytic activity, whereas all variant Fut2 enzymes showed strong catalytic activity. This functional analysis of the enzymes encoded by each Fut2 and Sec1 allele suggests that the association between one Sec1 allele and survival might be explained by a deficit of α1,2fucosyltransferase expression rather than by impaired catalytic activity.
Functional Diversity among Metallo-β-Lactamases: Characterization of the CAR-1 Enzyme of Erwinia carotovora

ABSTRACT Metallo-β-lactamases (MBLs) are zinc-dependent bacterial enzymes characterized by an efficient hydrolysis of carbapenems and a lack of sensitivity to commercially available β-lactamase inactivators. Apart from the acquired subclass B1 enzymes, which exhibit increasing clinical importance and whose evolutionary origin remains unclear, most MBLs are encoded by resident genes found in the genomes of organisms belonging to at least three distinct phyla. Using genome database mining, we identified an open reading frame (ORF) (ECA2849) encoding an MBL-like protein in the sequenced genome of Erwinia carotovora, an important plant pathogen. Although no detectable β-lactamase activity could be found in E. carotovora, a recombinant Escherichia coli strain in which the ECA2849 ORF was cloned showed decreased susceptibility to several β-lactams, while carbapenem MICs were surprisingly poorly affected. The enzyme, named CAR-1, was purified by means of ion-exchange chromatography steps, and its characterization revealed unique structural and functional features. This new MBL was able to efficiently hydrolyze cephalothin, cefuroxime, and cefotaxime and, to a lesser extent, penicillins and the other cephalosporins but only poorly hydrolyzed meropenem, while imipenem was not recognized. CAR-1 is the first example of a functional naturally occurring MBL in the family Enterobacteriaceae (order Enterobacteriales) and highlights the extraordinary structural and functional diversity exhibited by MBLs.
A Study on Performance of Hierarchical Mobile IPv6 in IP-Based Cellular Networks

SUMMARY Next-generation wireless/mobile networks will be IPbased cellular networks integrating Internet with the existing cellular networks. Recently, Hierarchical Mobile IPv6 (HMIPv6) was proposed by the Internet Engineering Task Force (IETF) for efficient mobility management. HMIPv6 reduces the amount of signaling and improves the performance of MIPv6 in terms of handoff latency. Although HMIPv6 is an efficient scheme, the performance of wireless networks is highly dependent on various system parameters such as user mobility model, packet arrival pattern, etc. Therefore, it is essential to analyze the network performance when HMIPv6 is deployed in IP-based cellular networks. In this paper, we develop two analytic models for the performance analysis of HMIPv6 in IP-based cellular networks, which are based on the random-walk and the fluid-flow models. Based on these analytic models, we formulate the location update cost and the packet delivery cost. Then, we analyze the impact of cell residence time and user population on the location update cost and the packet delivery cost, respectively. In addition, we study the variation of the total cost as the session-to-mobility ratio is changed and the optimal MAP domain size to minimize the total cost is also investigated.
Statistical models and regularization strategies in statistical image reconstruction of low-dose X-ray CT: a survey

Statistical image reconstruction (SIR) methods have shown potential to substantially improve the image quality of low-dose X-ray computed tomography (CT) as compared to the conventional filtered back-projection (FBP) method for various clinical tasks. According to the maximum a posterior (MAP) estimation, the SIR methods can be typically formulated by an objective function consisting of two terms: (1) data-fidelity (or equivalently, data-fitting or data-mismatch) term modeling the statistics of projection measurements, and (2) regularization (or equivalently, prior or penalty) term reflecting prior knowledge or expectation on the characteristics of the image to be reconstructed. Existing SIR methods for low-dose CT can be divided into two groups: (1) those that use calibrated transmitted photon counts (before log-transform) with penalized maximum likelihood (pML) criterion, and (2) those that use calibrated line-integrals (after log-transform) with penalized weighted least-squares (PWLS) criterion. Accurate statistical modeling of the projection measurements is a prerequisite for SIR, while the regularization term in the objective function also plays a critical role for successful image reconstruction. This paper reviews several statistical models on CT projection measurements and various regularization strategies incorporating prior knowledge or expected properties of the image to be reconstructed, which together formulate the objective function of the SIR methods for low-dose X-ray CT.
Second case of Beare–Stevenson syndrome with an FGFR2 Ser372Cys mutation

Beare–Stevenson syndrome is characterized by cutis gyrata, acanthosis nigricans, skin furrows, skin tags, craniosynostosis, Crouzonoid‐like features in some cases and cloverleaf skull in others, anogenital anomalies, and prominent umbilical stump. Reported causes are an FGFR2 Tyr375Cys mutation in nine cases and an FGFR2 Ser372Cys mutation in one case. Here, we report on a second patient with the FGFR2 Ser372Cys mutation. © 2008 Wiley‐Liss, Inc.
Sex differences in the ability to recognise non-verbal displays of emotion: A meta-analysis

The present study aimed to quantify the magnitude of sex differences in humans' ability to accurately recognise non-verbal emotional displays. Studies of relevance were those that required explicit labelling of discrete emotions presented in the visual and/or auditory modality. A final set of 551 effect sizes from 215 samples was included in a multilevel meta-analysis. The results showed a small overall advantage in favour of females on emotion recognition tasks (d = 0.19). However, the magnitude of that sex difference was moderated by several factors, namely specific emotion, emotion type (negative, positive), sex of the actor, sensory modality (visual, audio, audio-visual) and age of the participants. Method of presentation (computer, slides, print, etc.), type of measurement (response time, accuracy) and year of publication did not significantly contribute to variance in effect sizes. These findings are discussed in the context of social and biological explanations of sex differences in emotion recognition.
The Vacuum System of MAX IV Storage Rings: Installation and Conditioning

The installation of the vacuum system of the 3 GeV storage ring was started in November 2014 and finished in May 2015. In August 2015 the commissioning of the storage ring started, the first stored beam has been achieved on the 15 of September 2015. The installation of the vacuum system of the 1.5 GeV storage ring was done from September 2015 and the main part finished in December 2015, the connection to the Linac with the transfer line has been done in August 2016. In September 2016 the commissioning of the 1.5 GeV storage ring started with the first stored beam achieved on the 30 of September 2016. The vacuum system conditioning for the two rings was successful; the average dynamic pressure reduction and the increase in the lifetime with the accumulated beam dose is a demonstration of the good performance of the vacuum system. The installation procedure and the results of the conditioning together with the latest developments are introduced here.
Health information technology: fallacies and sober realities

Current research suggests that the rate of adoption of health information technology (HIT) is low, and that HIT may not have the touted beneficial effects on quality of care or costs. The twin issues of the failure of HIT adoption and of HIT efficacy stem primarily from a series of fallacies about HIT. We discuss 12 HIT fallacies and their implications for design and implementation. These fallacies must be understood and addressed for HIT to yield better results. Foundational cognitive and human factors engineering research and development are essential to better inform HIT development, deployment, and use.
Nucleic acid oxidation: an early feature of Alzheimer's disease

Studies of oxidative damage during the progression of Alzheimer's disease (AD) suggest its central role in disease pathogenesis. To investigate levels of nucleic acid oxidation in both early and late stages of AD, levels of multiple base adducts were quantified in nuclear and mitochondrial DNA from the superior and middle temporal gyri (SMTG), inferior parietal lobule (IPL), and cerebellum (CER) of age‐matched normal control subjects, subjects with mild cognitive impairment, preclinical AD, late‐stage AD, and non‐AD neurological disorders (diseased control; DC) using gas chromatography/mass spectrometry. Median levels of multiple DNA adducts in nuclear and mitochondrial DNA were significantly (p ≤ 0.05) elevated in the SMTG, IPL, and CER in multiple stages of AD and in DC subjects. Elevated levels of fapyguanine and fapyadenine in mitochondrial DNA suggest a hypoxic environment early in the progression of AD and in DC subjects. Overall, these data suggest that oxidative damage is an early event not only in the pathogenesis of AD but is also present in neurodegenerative diseases in general.
Prenatal and concurrent exposure to halogenated organic compounds and gene expression of CYP17A1, CYP19A1, and oestrogen receptor α and β genes

Objective To determine whether prenatal exposure to dichlorodiphenyl ethylene (DDE) and polychlorinated biphenyls (PCBs) and concurrent exposure to DDE, PCBs and polybrominated diphenylethers (PBDEs) affect gene expression of aromatase (CYP19A1), 17-α-hydroxylase (CYP17A1), and oestrogen receptors α and β (ESR 1 and ESR2). Methods Based on maternal PCB and DDE levels in the parent generation of the Michigan Fisheater Cohort determined between 1973 and 1991, individual prenatal exposures were estimated and have been published. In 2007, female adult offspring of this cohort were examined. Gene expression and concurrent lipid-adjusted exposures to DDE, PCBs and PBDEs were measured in blood and serum, respectively. Using mixed models and path analyses, gene-expression data were regressed on prenatal and concurrent exposures controlling for confounders. Results 139 daughters of Michigan fisheaters (65.3%) participated in the investigation. While prenatal PCB levels were statistically significantly associated with decreased expression of the aromatase and 17-α-hydroxylase genes, prenatal DDE levels were significantly related to increased gene expression of aromatase but not of 17-α-hydroxylase. The DDE association seems to be mediated by concurrent lipid-adjusted p,p′-DDE serum levels. Prenatal and concurrent exposure of both PCBs and DDE had comparable effects. No association was found for PBDEs or for the gene expression of ESR 1 and ESR2. Conclusions A 40-year antecedent prenatal exposure and concurrent levels of PCBs and DDE are associated with the expression of aromatase and 17-α-hydroxylase genes. Prenatal exposures to organochlorines may instigate long-term alterations of gene expression. Mechanisms of prenatal induction of persistent gene-expression alterations are speculated to be epigenetic in nature.
Study of the expression of CD30 in pterygia compared to healthy conjunctivas

Purpose The pterygium is characterized by a fibrovascular neoformation from the bulbar conjunctiva into the cornea. The recent discovery that abnormal markers associated with tumor diseases are identified in the pterygium strengthens the theory that the pterygium is a tumor-like disease rather than a degenerative disease. The CD30 molecule has been identified in neoplastic and normal epithelial proliferating cells. The aim of this study was to determine the expression of the CD30 molecule in the pterygium. Methods Immunohistochemical staining using an antibody to CD30 and to the Ki-67 nuclear antigen was performed on 25 pterygial specimens and 10 healthy conjunctivas. Results Strong immunostaining against CD30 was observed in all pterygium specimens, in contrast to the healthy conjunctivas that showed weak immono-positivity in only three cases. The staining was diffused, predominantly to the basal epithelium. The Ki-67 antigen was observed in the nucleus of the basal epithelium of the pterygial specimens, and no staining was observed in the healthy conjunctiva. When serial sections were stained with CD30 and Ki-67, the cells that expressed CD30 also expressed Ki-67. Conclusions The present study identified for the first time the existence of CD30 molecules in the basal epithelium of a pterygium. The fact that the positivity to Ki-67 in the basal epithelium of the pterygium correlated with the CD30 reactivity suggested that this protein could be associated with the uncontrolled cell proliferation of the epithelium in this pathology. The CD30 molecule could therefore be a suitable target to be inhibited using chimerical antibodies in pterygium diseases.
Photo-Crosslinkable Colloids: From Fluid Structure and Dynamics of Spheres to Suspensions of Ellipsoids

Recently-developed photo-crosslinkable PMMA (polymethylmethacrylate) colloidal spheres are a highly promising system for fundamental studies in colloidal physics and may have a wide range of future technological applications. We synthesize these colloids and characterize their size distribution. Their swelling in a density- and index- matching organic solvent system is demonstrated and we employ dynamic light scattering (DLS), as also the recently-developed confocal differential dynamic microscopy (ConDDM), to characterize the structure and the dynamics of a fluid bulk suspension of such colloids at different particle densities, detecting significant particle charging effects. We stretch these photo-crosslinkable spheres into ellipsoids. The fact that the ellipsoids are cross-linked allows them to be fluorescently stained, permitting a dense suspension of ellipsoids, a simple model of fluid matter, to be imaged by direct confocal microscopy.
Painless diabetic motor neuropathy: A variant of diabetic lumbosacral radiculoplexus Neuropathy?

Occasionally, diabetic patients develop painless, lower‐limb, motor predominant neuropathy. Whether this is a variant of diabetic lumbosacral radiculoplexus neuropathy (DLRPN) (a painful disorder from ischemic injury and microvasculitis), a variant of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) or another disorder is unsettled. Here, we characterize the clinical and pathological features of painless diabetic motor predominant neuropathy.
Effect of Training Status on Oxygen Consumption in Women After Resistance Exercise

Abstract Benton, MJ, Waggener, GT, and Swan, PD. Effect of training status on oxygen consumption in women after resistance exercise. J Strength Cond Res 30(3): 800–806, 2016—This study compared acute postexercise oxygen consumption in 11 trained women (age, 46.5 ± 1.6 years; body mass index [BMI], 28.4 ± 1.7 kg·m−2) and 11 untrained women (age, 46.5 ± 1.5 years; BMI, 27.5 ± 1.5 kg·m−2) after resistance exercise (RE). Resistance exercise consisted of 3 sets of 8 exercises (8–12 repetitions at 50–80% 1 repetition maximum). Oxygen consumption (V[Combining Dot Above]O2 ml·min−1) was measured before and after (0, 20, 40, 60, 90, and 120 minutes) RE. Immediately after cessation of RE (time 0), oxygen consumption increased in both trained and untrained women and remained significantly above baseline through 60 minutes after exercise (p < 0.01). Total oxygen consumption during recovery was 31.3 L in trained women and 27.4 L in untrained women (p = 0.07). In trained women, total oxygen consumption was strongly related to absolute (kg) lean mass (r = 0.88; p < 0.001), relative (kilogram per square meter) lean mass (r = 0.91; p < 0.001), and duration of exercise (r = 0.68; p ⩽ 0.05), but in untrained women, only training volume–load was related to total oxygen consumption (r = 0.67; p ⩽ 0.05). In trained women, 86% of the variance in oxygen consumption was explained by lean mass and exercise duration, whereas volume–load explained 45% in untrained women. Our findings suggest that, in women, resistance training increases metabolic activity of lean tissue. Postexercise energy costs of RE are determined by the duration of stimulation provided by RE rather than absolute work (volume–load) performed. This phenomenon may be related to type II muscle fibers and increased protein synthesis.