Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-sectional study on risk factors of HIV among female commercial sex workers in Cambodia

To describe epidemiological features on HIV prevalence among female commercial sex workers (CSWs), a cross-sectional study on sexual behaviour and serological prevalence was carried out in Cambodia. The CSWs were interviewed on their demographic characters and behaviour and their blood samples were taken for testing on sexually transmitted diseases, including HIV, Chlamydia trachomatis, syphilis, and hepatitis B. Associations between risk factors and HIV seropositivity were analysed. High seroprevalence of HIV and Chlamydia trachomatis IgG antibody (CT-IgG-Ab) was shown among the CSWs (54 and 81·7%, respectively). Univariate logistic regression analyses showed an association between HIV seropositivity and age, duration of prostitution, the number of clients per day and CT-IgG-Ab. Especially, high-titre chlamydial seropositivity showed a strong significant association with HIV prevalence. In multiple logistic regression analyses, CT-IgG-Ab with higher titre was significantly independently related to HIV infection. These suggest that existence of Chlamydia trachomatis is highly related to HIV prevalence.
Measuring Distances and Probing the Unresolved Stellar Populations of Galaxies Using Infrared Surface Brightness Fluctuations

To empirically calibrate the IR surface brightness fluctuation (SBF) distance scale and probe the properties of unresolved stellar populations, we measured fluctuations in 65 galaxies using NICMOS on the Hubble Space Telescope. The early-type galaxies in this sample include elliptical and S0 galaxies and spiral bulges in a variety of environments. Absolute fluctuation magnitudes in the F160W (1.6 μm) filter (F160W) were derived for each galaxy using previously measured I-band SBF and Cepheid variable star distances. F160W SBFs can be used to measure distances to early-type galaxies with a relative accuracy of ~10%, provided that the galaxy color is known to ~0.035 mag or better. Near-IR fluctuations can also reveal the properties of the most luminous stellar populations in galaxies. Comparison of F160W fluctuation magnitudes and optical colors to stellar population model predictions suggests that bluer elliptical and S0 galaxies have significantly younger populations than redder ones and may also be more metal-rich. There are no galaxies in this sample with fluctuation magnitudes consistent with old, metal-poor (t > 5 Gyr, [Fe/H] < -0.7) stellar population models. Composite stellar population models imply that bright fluctuations in the bluer galaxies may be the result of an episode of recent star formation in a fraction of the total mass of a galaxy. Age estimates from the F160W fluctuation magnitudes are consistent with those measured using the Hβ Balmer-line index. The two types of measurements make use of completely different techniques and are sensitive to stars in different evolutionary phases. Both techniques reveal the presence of intermediate-age stars in the early-type galaxies of this sample.
Adaptive Sensing Technique to Maximize Spectrum Utilization in Cognitive Radio

A cognitive radio (CR) system exploits spectrum bands that primary users (PUs) are licensed to use. The CR performs channel sensing to find spectrum opportunities. Conventional periodic sensing schemes require a long sensing time to detect a weak signal from the PU with fast channel-usage variation. Since the CR network should be quiet during a sensing period, a long sensing time results in low spectrum utilization. To improve spectrum utilization, we propose a novel sensing scheme that adaptively decides whether to sense the channel or to transmit the user data based on previous sensing results. The simulation results show that the proposed scheme significantly outperforms the conventional scheme.
Refractive Changes Induced by Strabismus Corrective Surgery in Adults

Purpose. To investigate refractive changes after strabismus correction procedures among adults. Methods. Retrospective chart review of adult patients who had horizontal recti muscles surgery with preoperative and postoperative cycloplegic refraction measurements. The preoperative refraction was mathematically subtracted from the postoperative refraction, and the induced refractive changes were statistically analyzed. Vector analysis was used to examine the magnitude of the toric change. The proportion of clinically significant refractive change was evaluated as well. Results. Thirty-one eyes from 22 subjects met the criteria and were included in the final analysis. A significant postoperative refractive change of the spherical equivalent towards myopia and a change of the astigmatism in the with-the-rule direction were observed. In a subset of 9 cases a third cycloplegic refraction measurement demonstrated stable refraction compared to the 1-month postoperative measurement. In 10 cases of single eye surgery, significant refractive changes were observed only in the operated side when compared to the sound eye. The induced surgical refractive change was of clinical significance (≥0.5 D) in 11 eyes of 9 patients (40.9% of patients). Conclusions. Refractive changes are a significant side effect of horizontal strabismus corrective surgery among adults. Therefore, patients should be informed about it prior to surgery and should be rerefracted in the postoperative period.
Integral Excision for K-Theory

If A is a homotopy cartesian square of ring spectra satisfying connectivity hypotheses, then the cube induced by Goodwillie's integral cyclotomic trace from K(A) to TC(A) is homotopy cartesian. In other words, the homotopy fiber of the cyclotomic trace satisfies excision. The method of proof gives as a spin-off new proofs of some old results, as well as some new results, about periodic cyclic homology, and - more relevantly for our current application - the T-Tate spectrum of topological Hochschild homology, where T is the circle group
Baby Boomers and Birth Certificates: Early-Life Socioeconomic Status and Cancer Risk in Adulthood

Background: Early-life socioeconomic status (SES) may play a role in cancer risk in adulthood. However, measuring SES retrospectively presents challenges. Parental occupation on the birth certificate is a novel method of ascertaining early-life SES that has not been applied in cancer epidemiology. Methods: For a Baby-Boom cohort born from 1945–1959 in two Utah counties, individual-level Nam-Powers SES (Np-SES) was derived from parental industry/occupation reported on birth certificates. Neighborhood SES was estimated from average household income of census tract at birth. Cancer incidence was determined by linkage to Utah Cancer Registry records through the Utah Population Database. Hazard ratios (HR) for cancer risk by SES quartile were estimated using Cox proportional hazards regression. Results: Females with low Np-SES at birth had lower risk of breast cancer compared with those in the highest Np-SES group [HRQ1/Q4 = 0.83; 95% confidence interval (CI), 0.72–0.97; HRQ2/Q4 = 0.81; 95% CI, 0.69–0.96]. Np-SES was inversely associated with melanoma (HRQ1/Q4 = 0.81; 95% CI, 0.67–0.98) and prostate cancer (HRQ1/Q4 = 0.70; 95% CI, 0.56–0.88). Women born into lower SES neighborhoods had significantly increased risk for invasive cervical cancer (HRQ1/Q4 = 1.44; 95% CI, 1.12–1.85; HRQ2/Q4 = 1.33; 95% CI, 1.04–1.72). Neighborhood SES had similar effects for melanoma and prostate cancers, but was not associated with female breast cancer. We found no association with SES for pancreas, lung, and colon and rectal cancers. Conclusions: Individual SES derived from parental occupation at birth was associated with altered risk for several cancer sites. Impact: This novel methodology can contribute to improved understanding of the role of early-life SES on cancer risk. Cancer Epidemiol Biomarkers Prev; 26(1); 75–84. ©2016 AACR.
The International Diversi fi cation Puzzle is not Worse Than You Think ∗

We study the implications of human capital hedging for international portfolio diversification. First, we show that given the degree of international economic integration observed in the data, very small domestic redistributive shocks can lead to home country bias in portfolio holdings. Second, we find that the seminal empirical result of Baxter and Jermann (1997) — that the international diversification puzzle is worsened if we consider the human capital hedging motive — is driven by an econometric misspecification that restricts the countries considered in their study to be economically not integrated. Moreover, once this misspecification is corrected, considering the human capital risk does not unequivocally worsen the puzzle, and in some cases helps explaining it. Third, we document that the substantial statistical uncertainty on measuring returns to the aggregate capital stock can rationalize the disagreements in the previous literature. Fourth, we find sharp evidence that if the set of assets that can be used to hedge aggregate human capital is restricted to publicly traded stocks, the human capital hedging motive has a negligible impact on optimal portfolio choice. This last finding is driven by the extremely small correlation between stock market returns and returns to human capital.
Mad2 and p27 expression profiles in colorectal cancer and its clinical significance.

AIM To investigate the expression of tumor suppressor gene p27 and spindle checkpoint gene Mad2 and to demonstrate their expression difference in colorectal cancer and normal mucosa and to evaluate its clinical significance. METHODS Immunohistochemical staining was used for detection of expression of Mad2 and p27 in colorectal cancer and its corresponding normal mucosa. RESULTS Mad2 was significantly overexpressed in colorectal cancer compared with corresponding normal mucosa (P<0.01, chi(2) = 7.5), and it was related to the differentiation of adenocarcinoma, lymph node metastasis and survival period after excision (P<0.05, chi(2) = 7.72, chi(2) = 4.302, chi(2) = 6.234). The rate of p27 positive expression in adenocarcinomas and normal mucosa was 40% and 80% respectively. There was a significant difference in p27 expression between adenocarcinomas and normal mucosa (P<0.001, chi(2) = 13.333), which was related to the differentiation degree of adenoca rcinoma and lymph node metastasis (P<0.05, chi(2) = 8.901 chi(2) = 4). The positive expression of p27 was not correlated with survival period after excision. CONCLUSION Defect of spindle checkpoint gene Mad2 and mutation of p27 gene are involved mainly in colorectal carcinogenesis and associated with prognosis of colorectal cancer.
Tunable Membrane Binding of the Intrinsically Disordered Dehydrin Lti30, a Cold-Induced Plant Stress Protein[W]

The dehydrin family of proteins is upregulated in response to desiccation and cold stress and is thought to protect the plant by stabilizing the plasma membrane. This study characterizes the interaction between a typical dehydrin (Lti30) and lipid membranes. Dehydrins are intrinsically disordered plant proteins whose expression is upregulated under conditions of desiccation and cold stress. Their molecular function in ensuring plant survival is not yet known, but several studies suggest their involvement in membrane stabilization. The dehydrins are characterized by a broad repertoire of conserved and repetitive sequences, out of which the archetypical K-segment has been implicated in membrane binding. To elucidate the molecular mechanism of these K-segments, we examined the interaction between lipid membranes and a dehydrin with a basic functional sequence composition: Lti30, comprising only K-segments. Our results show that Lti30 interacts electrostatically with vesicles of both zwitterionic (phosphatidyl choline) and negatively charged phospholipids (phosphatidyl glycerol, phosphatidyl serine, and phosphatidic acid) with a stronger binding to membranes with high negative surface potential. The membrane interaction lowers the temperature of the main lipid phase transition, consistent with Lti30’s proposed role in cold tolerance. Moreover, the membrane binding promotes the assembly of lipid vesicles into large and easily distinguishable aggregates. Using these aggregates as binding markers, we identify three factors that regulate the lipid interaction of Lti30 in vitro: (1) a pH dependent His on/off switch, (2) phosphorylation by protein kinase C, and (3) reversal of membrane binding by proteolytic digest.
Do 5-Year-Old Children Perform Dual-Task Coordination Better Than AD Patients?

Objective: A cross-sectional study was carried out to examine the pattern of changes in the capacity to coordinate attention between two simultaneously performed tasks in a group of 570 volunteers, from 5 to 17 years old. Method: The results revealed that the ability to coordinate attention increases with age, reaching adult values by age 15 years. Also, these results were compared with the performance in the same dual task of healthy elderly and Alzheimer disease (AD) patients found in a previous study. Results: The analysis indicated that AD patients showed a lower dual-tasking capacity than 5-year-old children, whereas the elderly presented a significantly higher ability than 5-year-old children and no significant differences with respect to young adults. Conclusion: These findings may suggest the presence of a working memory system’s mechanism that enables the division of attention, which is strengthened by the maturation of prefrontal cortex, and impaired in AD.
Randomized Controlled Pilot Trial of Behavioral Insomnia Treatment for Chronic Migraine With Comorbid Insomnia

Migraine frequently co‐occurs with and is triggered by sleep disturbance, particularly insomnia, and the large majority of patients with chronic migraine (CM) have comorbid insomnia. Limited evidence suggests that behavioral regulation of sleep may reduce migraine frequency, but studies to date have not assessed the viability of stimulus control and sleep restriction interventions or included objective measurement of sleep parameters. The aim of this study, thus, was to pilot‐test the efficacy of a brief behavioral insomnia intervention for adults with CM and comorbid insomnia; headache diaries and actigraphy were included to assess outcomes throughout the trial.
A potential mechanism for compensation in the blue—yellow visual channel

Due to their unique contribution to human vision, the short (S)-wavelength sensitive cones, their anatomical projections and, more recently, the cortical representation of their function, have motivated intense scientific interest. The principal study of the visual channel associated with S-cone projections has been conducted using psychophysical, neurophysiological, and ex vivo anatomical techniques, whereas more recent research on the pathway has employed functional magnetic resonance imaging (fMRI). The purpose of this manuscript is to present a perspective regarding the means by which color signals within this visual channel are processed in the brain, namely how differences in short-wavelength light transmission caused by intraocular, pre-receptoral filtration are compensated for. Recent results from fMRI and psychophysical studies indicate the existence of a frequency-dependent signal amplification mechanism, whereby lower frequencies result in an amplification of S-cone signals. This finding could motivate a future research direction for determining the localization of blue—yellow color processing and neural compensation in the blue–yellow visual channel.
Edinburgh Research Explorer a Systematic Analysis of Translation Model Search Spaces a Systematic Analysis of Translation Model Search Spaces

General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact openaccess@ed.ac. uk providing details, and we will remove access to the work immediately and investigate your claim. Abstract Translation systems are complex, and most metrics do little to pinpoint causes of error or isolate system differences. We use a simple technique to discover induction errors, which occur when good translations are absent from model search spaces. Our results show that a common pruning heuristic drastically increases induction error, and also strongly suggest that the search spaces of phrase-based and hierarchical phrase-based models are highly overlapping despite the well known structural differences.
Late Pliocene–Early Pleistocene North Atlantic Circulation: Integrating Dinocyst Assemblages and Foraminiferal Geochemistry

During the Late Pliocene, between 3.3 Ma and 2.6 Ma, tectonic events changed ocean basin interactions against a background of shifting orbital forcing mechanisms and a global cooling trend. A climate system that had been locked in a stable, warm state gradually transformed into one typified by the highamplitude glacial–interglacial fluctuations characteristic of the later Quaternary. The onset of Northern Hemisphere glaciations in the Late Pliocene marks an important step in this transition, due to the role of feedback mechanisms including ice albedo. A crucial factor in this Northern Hemisphere ice sheet expansion is the North Atlantic surface ocean circulation. To evaluate how they are linked, a ca. 200-kyr time slab spanning 2782-2520 ka (Late Pliocene–Early Pleistocene) was analyzed at millennial scale resolution from eastern North Atlantic Deep Sea Drilling Project (DSDP) Site 610 and Integrated Ocean Drilling Program (IODP) Site U1313. The causes of the Plio-Pleistocene climatic turnover are compared to that of the well-documented Marine Isotope Stage (MIS) M2 occurring in the Late Pliocene (3.3 Ma). MIS M2, a severe glacial event seen as a precursor to later Quaternary-style glaciations, was investigated from western North Atlantic DSDP Site 603. Utilizing a same-sample methodology, two paleoceanographic proxies were used: (1) dinocyst assemblages, and (2) foraminiferal geochemistry (δ18O and Mg/Ca). Dinocysts are proven tracers of sea-surface temperature (SST), salinity, nutrient supply, and sea ice cover, and are analyzed here to characterize the overlying water masses at the studied sites. Strong dinocyst assemblage fluctuations attest to variations in the influence of the North Atlantic Current (NAC). Using Mg/Ca ratios for the planktonic foraminifer Globigerina bulloides to determine absolute SSTs allows salinity changes to be reconstructed when com-iiibined with stable oxygen isotopes. This study shows a persistent Gulf Stream–NAC in the western North Atlantic during MIS M2, favoring a southern shift of the NAC over a shutdown of the thermohaline circulation. At the newly established Plio-Pleistocene boundary, a profound turnover in dinoflagellate cyst assemblages reveals a shift in ocean mode during MIS 104 (2.6 Ma). Three distinct dinocyst ecozones demonstrate this fundamental reorganization of the North Atlantic circulation.
Software estimation using a generic-processor model

Previous work in hardware-software co-design has addressed issues in system modeling, partitioning, and mixed module simulation and integration. Software estimation, which provides software metrics to assist hardware-software partitioning, has not been extensively studied. We present a generic-processor model for estimating execution time and program-memory size of a specification to be executed on a given processor. Experiments have shown that our estimator is fairly accurate and fast when applied to a wide variety of designs. <<ETX>>
Dimensions of Difficulty in Translating Natural Language into First-Order Logic

In this paper, we present a study of a large corpus of student logic exercises in which we explore the relationship between two distinct measures of difficulty: the proportion of students whose initial attempt at a given natural language to first-order logic translation is incorrect, and the average number of attempts that are required in order to resolve the error once it has been made. We demonstrate that these measures are broadly correlated, but that certain circum- stances can make a hard problem easy to fix, or an easy problem hard to fix. The analysis also reveals some unexpected results in terms of what students find dif- ficult. This has consequences for the delivery of feedback in the Grade Grinder, our automated logic assessment tool; in particular, it suggests we should provide different kinds of assistance depending upon the specific 'difficulty profile' of the exercise.
Slowness of movement in Parkinson's disease

Loss of the ability to move is the most characteristic and fundamental motor deficit in Parkinson’s disease. Parkinsonian patients exhibit akinesia (inability to initiate movement), hypokinesia (reduced movement), and bradykinesia (slowness of the movement itself). (All these phenomena will be subsumed under the title akinesia.) Rigid muscles may contribute to akinesia, but they are not the cause. This is evident from the effects of both stereotactic surgery and treatment with levodopa. Stereotactic thalamotomy is an effective means of abolishing contralateral rigidity (and tremor), but does not relieve akinesia, which progresses to cause increasing disability. Levodopa therapy, on the other hand, dramatically relieves akinesia, even in those who have undergone previous stereotactic surgery. The akinesia of Parkinson’s disease represents a major negative symptom and, as such, probably gives the best clue as to what goes wrong with basal ganglia function in that condition (1,2). However, analysis of the pathophysiology of akinesia has proved difficult. One is dealing with higher-order motor function in all its complexity. Normal Movement Two approaches have been employed to investigate events in the brain before the initiation of movement in Parkinson’s disease; (a) the study of reaction times, and (b) the investigation of the Bereitschaftspotential.
Use of Cone Beam Computed Tomography in Endodontics

Cone Beam Computed Tomography (CBCT) is a diagnostic imaging modality that provides high-quality, accurate three-dimensional (3D) representations of the osseous elements of the maxillofacial skeleton. CBCT systems are available that provide small field of view images at low dose with sufficient spatial resolution for applications in endodontic diagnosis, treatment guidance, and posttreatment evaluation. This article provides a literature review and pictorial demonstration of CBCT as an imaging adjunct for endodontics.
Experiments of Opinion Analysis On Two Corpora MPQA and NTCIR-6

This paper describes the algorithms and linguistic features used in our participating system for the opinion analysis pilot task at NTCIR-6. It presents and discusses the results of our system on the opinion analysis task. It also presents our experiments of opinion analysis on the two corpora MPQA and NTCIR-6, by us-ing our learning based system. Our system was base on the SVM learning. It achieved state of the art re-sults on the MPQA corpus for the two problems, opin-ionated sentence recognition and opinion holder extraction. The results using the NTCIR-6 English corpus for both training and testing are certainly among the ﬁrst ones. Our results on the opinionated sentence recognition sub-task of the NTCIR-6 were encouraging. The results on the English evaluation of the NTCIR-6 opinion analysis task were obtained from the models learned from the MPQA corpus. The lower results on the NTCIR-6 opinion holder extraction sub-task, in comparison with those using each corpus for both training and testing, may possibly show that there exist substantial differences between the MPQA corpus and the NTCIR-6 English corpus.