Miracle-dz/UniFAR-FTUs huggingface dataset:
Multicultural Literature for Children and Young Adults

There is much discussion of multiculturalism in education. This is especially true of multicultural literature for children and young adults. The rise of multicultural literature is a political rather than a literary movement; it is a movement to claim space in literature and in education for historically marginalized social groups rather than one to renovate the craft of literature itself. Multicultural literature has been closely bound with the cause of multiculturalism in general and thus has been confronted with resistance from conservatives. This book discusses many of the controversial issues surrounding multicultural literature for children and young adults. The volume begins with a look at some of the foundational and theoretical issues related to multicultural literature. The second part of the book addresses issues related to the creation and critique of multicultural literature, including the authorship of such works and the role of the reader in determining whether or not a work is multicultural. The third looks at the place of multicultural literature in the education of children and young adults. Throughout its discussion, the book makes extensive references to a large body of multicultural fiction and provides a thorough review of research on this important topic.
Distinguishing between enduring and dynamic concussion symptoms: applying Generalisability Theory to the Rivermead Post Concussion Symptoms Questionnaire (RPQ)

Background The Rivermead Post Concussion Symptoms Questionnaire (RPQ) is a widely-used, 16-item measure of concussion symptoms yet its ability to assess change in the symptom experience over time has come under criticism. We applied Generalisability theory to differentiate between dynamic and enduring aspects of post-concussion symptoms and to examine sources of measurement error in the RPQ. Materials and Methods Generalisability theory was applied using the longitudinal design with persons as the object of measurement. Patients with a traumatic brain injury (n = 145; aged ≥16 years) were assessed at three time occasions (1, 6 and 12 months post-injury) using the RPQ. Results The RPQ showed overall strong generalisability of scores (G = .98) across persons and occasions with a minor proportion of variance attributed to the dynamic aspect of symptoms reflected by interaction between person and occasion. Items measuring concentration, fatigue, restlessness and irritability reflected more dynamic patterns compared to more enduring patterns of sensitivity to noise, impatience, nausea and sleep disturbance. Conclusion The RPQ demonstrated strong reliability in assessing enduring post-concussion symptoms but its ability to assess dynamic symptoms is limited. Clinicians should exercise caution in use of the RPQ to track dynamic symptom change over time. Further investigation is necessary to enhance the RPQ’s ability to assess dynamic symptoms and to address measurement error associated with individual items.
Spiritual perspectives, needs and nursing interventions of Christian African-Americans.

BACKGROUND Although the amount of literature on spiritual needs and care has increased, in practice there has been little change in how nurses assess spiritual need. This suggests that not all spiritual needs of patients are being addressed. Based on the assumption that spiritual needs vary by culture, this study focused on one subgroup, namely Christian African-Americans. AIMS The aim of this paper is to report a study examining spiritual perspectives, spiritual needs and desired nursing interventions during hospitalization identified by Christian African-Americans. METHODS A descriptive correlational design was employed. A convenience sample (n = 44) was recruited from three African-American churches. Descriptive statistics were calculated, and one-way anovas used to examine spiritual perspectives and spiritual values. Content analysis was used to analyse and summarize qualitative data. Instruments included the Spiritual Perspective Scale (SPS) and two open-ended questions. RESULTS The mean age of participants was 56 years (range 19-84). The majority was female (86%); 71% of respondents strongly agreed that they had spiritual needs to be met during hospitalization. Mean score for the SPS was 5.7 (sd = 0.36). Respondents used a total of 103 phrases to describe spiritual needs, based on three dimensions of connectedness: connectedness to God (50 phrases), connectedness to others (37 phrases) and connectedness to self (16 phrases). Desired nursing interventions included: participating in spiritual activities (n = 41); demonstrating caring qualities (n = 27); providing comforting measures (n = 13); providing reassurance (n = 9); recognizing the spiritual caregiver role (n = 7); and incorporating diversity in care (n = 3). CONCLUSIONS The findings provide information for nurses to facilitate development of culturally appropriate spiritual nursing interventions.
Reconstruction of the oesophagus using pedicle diaphragm and omentum flaps in a dog: a case report

A two-years-old, intact female, Shih-Tzu dog weighing 5 kg was presented to the Chonbuk Animal Medical Centre, College of Veterinary Medicine, Chonbuk National University, with the history of bone ingestion before two days. The survey radiographs of the thorax revealed a bone at the caudal thoracic oesophagus. An oesophagram was performed which did not reveal any oesophageal leakage or perforation. The left caudolateral thoracotomy was performed and the caudal oesophagus was found partially necrosed, friable and inflamed. The necrosed, friable part was removed and the oesophageal defect was reconstructed using a full-thickness muscle flap collected from the diaphragm. A part of the omentum was mobilized from the abdomen and sutured over the reconstructed site of the oesophagus to aid healing. Oesophagoscopy after nine days postoperatively showed a good adhesion of the diaphragm flap. The patient showed normal activity after 12 days and no complications were observed during a one-year follow up period. The pedicle flap collected from the left hemidiaphragm in addition to the omentum flap can be successfully used to reconstruct the circumferential oesophageal defect.
Serum 25-Hydroxyvitamin D Concentration and Cognitive Impairment

Vitamin D may be of interest in the prevention of cognitive impairment, though previous findings are inconclusive. Participants were 1766 adults aged 65 years and older from the Health Survey for England 2000, a nationally representative population-based study. Cognitive impairment was assessed using the Abbreviated Mental Test Score. The cross-sectional relation of serum 25-hydroxyvitamin D quartiles to cognitive impairment was modeled using logistic regression. In all, 212 participants (12%) were cognitively impaired. Odds ratios (95% confidence intervals) for cognitive impairment in the first (8-30 nmol/L), second (31-44 nmol/L), and third (45-65 nmol/L) quartiles of serum 25-hydroxyvitamin D compared with the fourth (66-170 nmol/L) were 2.3 (1.4-3.8), 1.4 (0.8-2.4), and 1.1 (0.6-1.9), after adjustment for age, sex, education, ethnicity, season of testing, and additional risk factors for cognitive impairment (P for linear trend = .001). Our data suggest low serum 25-hydroxyvitamin D is associated with increased odds of cognitive impairment.
The impact of testicular and accessory sex gland function on sperm chromatin integrity as assessed by the sperm chromatin structure assay (SCSA).

BACKGROUND The sperm chromatin structure assay (SCSA) provides an objective assessment of sperm chromatin integrity, which is essential for normal sperm function. SCSA is valuable as a fertility marker in epidemiological studies and in the clinical situation. Little is known about the impact of testicular and post-testicular function on SCSA parameters. METHODS Ejaculates from 278 military conscripts of median age 18.1 (range 18-21) years were included. Levels of reproductive hormones, the length of the CAG repeat of the androgen receptor gene, sperm concentration, abstinence period and biochemical parameters of epididymal and accessory sex gland secretions were correlated to the SCSA parameters, DNA fragmentation index (DFI) and highly DNA stainable (HDS) cells. RESULTS Negative correlations were found between sperm concentration and DFI (r = -0.119, P = 0.049) and HDS (r = -0.513, P < 0.0001). DFI was negatively correlated with levels of estradiol (r = -0.19, P = 0.002) and free testosterone (r = -0.13, P = 0.03). DFI also correlated positively with abstinence time (r = 0.17, P = 0.005), and with seminal concentrations of fructose (r = 0.18, P = 0.004) and zinc (r = 0.12, P = 0.04). CONCLUSIONS Sex steroid production, spermatogenic function, abstinence time and seminal vesicle function appear to impact on sperm chromatin integrity and thereby on sperm fertilizing capacity. These findings may improve present understanding of the pathophysiology of male infertility.
Prediction of Protein-Protein Interactions Using Pairwise Alignment and Inter-Domain Linker Region

One of the central problems in modern biology is to identify the complete set of interactions among the proteins in a cell. The structural interaction of proteins and their domains in networks is one of the most basic molecular mechanisms for biological cells. Structural evidence indicates that, interacting pairs of close homologs usually interact in the same way. In this article, we make use of both homology and inter-domain linker region knowledge to predict interaction between protein pairs solely by amino acid sequence information. High quality core set of 150 yeast proteins obtained from the Database of Interacting Proteins (DIP) was considered to test the accuracy of the proposed method. The strongest prediction of the method reached over 70% accuracy. These results show great potential for the proposed method.
Leap motion controlled videogame-based therapy for rehabilitation of elderly patients with subacute stroke: a feasibility pilot study

Abstract Background: The leap motion controller (LMC) is a new optoelectronic system for capturing motion of both hands and controlling a virtual environment. Differently from previous devices, it optoelectronically tracks the fine movements of fingers neither using glows nor markers. Objective: This pilot study explored the feasibility of adapting the LMC, developed for videogames, to neurorehabilitation of elderly with subacute stroke. Methods: Four elderly patients (71.50 ± 4.51 years old) affected by stroke in subacute phase were enrolled and tested in a cross-over pilot trial in which six sessions of 30 minutes of LMC videogame-based therapy were added on conventional therapy. Measurements involved participation to the sessions, evaluated by means of the Pittsburgh Rehabilitation Participation Scale, hand ability and grasp force evaluated respectively by means of the Abilhand Scale and by means of the dynamometer. Results: Neither adverse effects nor spasticity increments were observed during LMC training. Participation to the sessions was excellent in three patients and very good in one patient during the LMC trial. In this period, patients showed a significantly higher improvement in hand abilities (P = 0.028) and grasp force (P = 0.006). Conclusions: This feasibility pilot study was the first one using leap motion controller for conducting a videogame-based therapy. This study provided a proof of concept that LMC can be a suitable tool even for elderly patients with subacute stroke. LMC training was in fact performed with a high level of active participation, without adverse effects, and contributed to increase the recovery of hand abilities.
Change of b-Dimension with Swelling of Montmorillonite

The effect of swelling on the b-dimension of Na-saturated, Upton, Wyoming montmorillonite was re-examined using powdered silicon as an internal standard. After being corrected with reference to the internal standard, the b-dimension did not increase through the entire range of swelling as reported previously. It increased up to a water content of ~3.0g/g montmorillonite and remained constant thereafter. However, the diffraction peak of the internal standard shifted towards lower angles at higher water contents. This shift was attributed to a relaxation of the wetter samples away from the knife edge of the diffractometer. Presumably, a similar relaxation occurred in the earlier study and was responsible for the apparent increase in b-dimension at water contents above ~3.0g/g.The b-dimension of Upton montmorillonite saturated with different cations was determined using powdered silicon and a colloidal quartz impurity as internal standards. The water content at maximal swelling decreased as the b-dimension increased.
The Index Poisoning Attack in P2P File Sharing Systems

P2P file-sharing systems have indexes, which users search to find locations of desired titles. In the index poisoning attack, the attacker inserts massive numbers of bogus records into the index for a set of targeted titles. As a result, when a user searches for a targeted title, the index returns bogus results, such as bogus file identifiers, bogus IP addresses, or bogus port numbers. In this paper we first show that both structured and unstructured P2P file-sharing systems are highly vulnerable to the index poisoning attack. We then develop a novel and efficient methodology for estimating index poisoning levels and pollution levels in file-sharing systems. The methodology is efficient in that involves neither the downloading nor the analysis of binary content files. We deploy data-harvesting platforms for FastTrack, an unstructured file-sharing system, and Overnet, a DHT-based file-sharing system. Applying our methodology to harvested data, we find that index poisoning is pervasive in both systems. We also outline a distributed blacklisting procedure for countering the index poisoning and pollution attacks.
Advances on Spectrum Sensing for Cognitive Radio Networks: Theory and Applications

Due to the under-utilization problem of the allocated radio spectrum, cognitive radio (CR) communications have recently emerged as a reliable and effective solution. Among various network models, this survey paper focuses on the enabling techniques for interweave CR networks which have received great attention from standards perspective due to its reliability to achieve the required quality-of-service. Spectrum sensing provides the essential information to enable this interweave communications in which primary and secondary users are not allowed to access the medium concurrently. Several researchers have already considered various aspects to realize efficient techniques for spectrum sensing. In this direction, this survey paper provides a detailed review of the state-of-the-art related to the application of spectrum sensing in CR communications. Starting with the basic principles and the main features of interweave communications, this paper provides a classification of the main approaches based on the radio parameters. Subsequently, we review the existing spectrum sensing works applied to different categories such as narrowband sensing, narrowband spectrum monitoring, wideband sensing, cooperative sensing, practical implementation considerations for various techniques, and the recent standards that rely on the interweave network model. Furthermore, we present the latest advances related to the implementation of the legacy spectrum sensing approaches. Finally, we conclude this survey paper with some suggested open research challenges and future directions for the CR networks in next generation Internet-of-Things applications.
Strength training for the warfighter.

Optimizing strength training for the warfighter is challenged by past training philosophies that no longer serve the modern warfighter facing the "anaerobic battlefield. " Training approaches for integration of strength with other needed physical capabilities have been shown to require a periodization model that has the flexibility for changes and is able to adapt to ever-changing circumstances affecting the quality of workouts. Additionally, sequencing of workouts to limit over-reaching and development of overtraining syndromes that end in loss of duty time and injury are paramount to long-term success. Allowing adequate time for rest and recovery and recognizing the negative influences of extreme exercise programs and excessive endurance training will be vital in moving physical training programs into a more modern perspective as used by elite strength-power anaerobic athletes in sports today. Because the warfighter is an elite athlete, it is time that training approaches that are scientifically based are updated within the military to match the functional demands of modern warfare and are given greater credence and value at the command levels. A needs analysis, development of periodized training modules, and individualization of programs are needed to optimize the strength of the modern warfighter. We now have the knowledge, professional coaches and nonprofit organization certifications with continuing education units, and modern training technology to allow this to happen. Ultimately, it only takes command decisions and implementation to make this possible.
The isolated neutron star candidate RBS1223 (1RXS J130848.6+212708)

In the ROSAT Bright Survey (RBS) we have almost completely optically identified the brightest ~2000 high-galactic latitude sources from the ROSAT All-Sky Survey Bright Source Catalogue (1RXS). A small number of sources has empty X-ray error circles on optical images. ROSAT HRI follow-up observations of RBS1223 (=1RXS J130848.6+212708), a soft object with extreme X-ray to optical flux ratio, have confirmed a relatively bright X-ray source, whose position could be determined to an accuracy of 1.6 arcsec (90%) due to the presence of a nearby, X-ray detected bright star. Deep Keck R- and B-band images of the field were taken, but the refined X-ray error circle remains empty to a limiting magnitude B ~ 26m. With an X-ray to optical flux ratio of log (f_X/f_opt)>4.1 this object is almost certainly an isolated neutron star, similar to the two so far best-known examples RX J1856.4-3754 and RX J0720.4-3125. We discuss limits on the number of similar objects in the RBS catalogue.
Mitochondrial Cu,Zn-Superoxide Dismutase Mediates Pulmonary Fibrosis by Augmenting H2O2 Generation*

The release of H2O2 from alveolar macrophages has been linked to the development of pulmonary fibrosis, but little is known about its source or mechanism of production. We found that alveolar macrophages from asbestosis patients spontaneously produce high levels of H2O2 and have high expression of Cu,Zn-superoxide dismutase (SOD). Because Cu,Zn-SOD is found in the mitochondrial intermembrane space (IMS), we hypothesized that mitochondrial Cu,Zn-SOD-mediated H2O2 generation contributed to pulmonary fibrosis. Asbestos-induced translocation of Cu,Zn-SOD to the IMS was unique to macrophages and dependent on functional mitochondrial respiration and the presence of at least one of the conserved cysteines required for disulfide bond formation. These conserved cysteine residues were also necessary for enzyme activation and H2O2 generation. Cu,Zn-SOD-mediated H2O2 generation was inhibited by knockdown of the iron-sulfur protein, Rieske, in complex III. The role of Cu,Zn-SOD was biologically relevant in that Cu,Zn-SOD−/− mice generated significantly less H2O2 and had less oxidant stress in bronchoalveolar lavage fluid and lung parenchyma. Furthermore, Cu,Zn-SOD−/− mice did not develop pulmonary fibrosis, and knockdown of Cu,Zn-SOD in monocytes attenuated collagen I deposition by lung fibroblasts. Our findings demonstrate a novel mechanism for the pathogenesis of pulmonary fibrosis where the antioxidant enzyme Cu,Zn-SOD translocates to the mitochondrial IMS to increase H2O2 generation in alveolar macrophages.
Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos

Blastocyst injection and morula aggregation are commonly used to evaluate stem cell pluripotency based on chimeric contribution of the stem cells. To assess the protocols for generating chimeras from stem cells, 8-cell mouse embryos were either injected or cocultured with mouse embryonic stem cells and induced pluripotent stem cells, respectively. Although a significantly higher chimera rate resulted from blastocyst injection, the highest germline contribution resulted from injection of 8-cell embryos with embryonic stem cells. The fully agouti colored chimeras were generated from both injection and coculture of 8-cell embryos with embryonic stem cells. Additionally, microsatellite DNA screening showed that the fully agouti colored chimeras were fully embryonic stem cell derived mice. Unlike embryonic stem cells, the mouse chimeras were only generated from injection of 8-cell embryos with induced pluripotent stem cells and none of these showed germline transmission. The results indicated that injection of 8-cell embryos is the most efficient method for assessing stem cell pluripotency and generating induced pluripotent stem cell chimeras, embryonic stem cell chimeras with germline transmission, and fully mouse embryonic stem cell derived mice.
Mechanisms of MEOX1 and MEOX2 Regulation of the Cyclin Dependent Kinase Inhibitors p21CIP1/WAF1 and p16INK4a in Vascular Endothelial Cells

Senescence, the state of permanent cell cycle arrest, has been associated with endothelial cell dysfunction and atherosclerosis. The cyclin dependent kinase inhibitors p21CIP1/WAF1 and p16INK4a govern the G1/S cell cycle checkpoint and are essential for determining whether a cell enters into an arrested state. The homeodomain transcription factor MEOX2 is an important regulator of vascular cell proliferation and is a direct transcriptional activator of both p21CIP1/WAF1 and p16INK4a. MEOX1 and MEOX2 have been shown to be partially functionally redundant during development, suggesting that they regulate similar target genes in vivo. We compared the ability of MEOX1 and MEOX2 to activate p21CIP1/WAF1 and p16INK4a expression and induce endothelial cell cycle arrest. Our results demonstrate for the first time that MEOX1 regulates the MEOX2 target genes p21CIP1/WAF1 and p16INK4a. In addition, increased expression of either of the MEOX homeodomain transcription factors leads to cell cycle arrest and endothelial cell senescence. Furthermore, we show that the mechanism of transcriptional activation of these cyclin dependent kinase inhibitor genes by MEOX1 and MEOX2 is distinct. MEOX1 and MEOX2 activate p16INK4a in a DNA binding dependent manner, whereas they induce p21CIP1/WAF1 in a DNA binding independent manner.
Role Model Performance Effects on Development of Entrepreneurial Career Preference

Critics of the trait approach to the study of entrepreneurship have called for adaptation of theory from other disciplines to explain entrepreneurial behavior. This study responds by focusing on the first step in the process by which entrepreneurial career preference is developed. Social Learning Theory was used to investigate the link between a parent role model and development of preference for an entrepreneurial career. Results indicated that presence of a parent entrepreneurial role model was associated with increased education and training aspirations, task self-efficacy, and expectancy for an entrepreneurial career. Two dimensions of entrepreneurial career preference, entrepreneurial preparedness and expectancy, were identified.