Miracle-dz/UniFAR-FTUs huggingface dataset:
A Randomized Controlled Trial on Parenteral Nutrition, Oxidative Stress, and Chronic Lung Diseases in Preterm Infants

Objectives:To evaluate the effect of trace elements (TEs), when added to total parenteral nutrition (TPN) solutions, on peroxides load, and to test the hypothesis that protection of TPN from light can decrease peroxides load and is associated with improvement in oxidant-related clinical outcomes in preterm infants. Subjects and Methods:A total of 80 preterm infants were randomized to 1 of 4 groups (n = 20 each): group 1 received a mixture of dextrose and amino acids; group 2 received a mixture of dextrose, amino acids, and lipid emulsion; group 3 received dextrose, amino acids, lipid emulsion, and multivitamins (MVP); and group 4 received dextrose, amino acids, lipid emulsion, MVP, and TEs. Each group was subdivided into photo-protected and photo-exposed subgroups (n = 10 each). Using ferrous oxidation of xylenol orange technique, we measured the baseline level of excreted urinary peroxides before and 48 hours after starting TPN. We examined the association among light protection, urinary peroxides, and clinical outcomes of these infants. Results:Baseline urinary peroxides ranged between 5.5 and 24.8 μmol/L. A significant increase in urinary peroxides was observed in all groups after receiving TPN. The use of TEs did not affect peroxide production. In regression analysis, the addition of MVP (P < 0.0001) and the exposure to light (P = 0.02) were significantly associated with increased urinary peroxides. In the overall population, light exposure was associated with a significant increase in the incidence of chronic lung disease (adjusted OR 9.26, confidence interval 1.2–73; P = 0.03) but had no effect on mortality, necrotizing enterocolitis, or sepsis. Conclusions:TEs in TPN solutions have no effect on the production of urinary peroxides. Addition of MVP and exposure of TPN to light are the 2 major sources of peroxides in TPN. Protection from ambient light is associated with a decrease in chronic lung disease.
An exploratory case study of the preparation of secondary teachers to meet special education needs in the general classroom

Abstract Teaching teachers to effectively adapt the general curriculum for students with disabilities in general education classrooms is a challenging and often overwhelming task for preservice methods faculty. In order to examine the preparation needs of secondary education teachers and the realities of today's secondary education classrooms, inservice secondary education teachers and preservice methods faculty were matched in intensive, asynchronistic, online discussions. An initial attitude, knowledge, and skills survey was completed by both groups of participants and compared to the results of the online discussions. Findings of this small case study revealed that (a) theoretical knowledge in best practices of special education are not adequately addressed in secondary education preparation programs, and (b) both methods faculty and inservice secondary teachers need to learn effective content enhancement practices, principles of strategy instruction, effective curriculum design, and technology skills. Educational implications of the findings for professionals in teacher education are discussed.
Intraabdominal lymphatic mapping to direct selective pelvic and paraaortic lymphadenectomy in women with high-risk endometrial cancer: results of a pilot study.

OBJECTIVE To determine the feasibility of intraperitoneal lymphatic mapping of the uterine fundus as a means of identifying target sites for lymph node biopsy during staging laparotomy and to develop preliminary experience with the technique. METHODS Fifteen women with high-risk endometrial tumors were entered on this Institutional Review Board-approved pilot study. At laparotomy, isosulfan blue dye (1.0 ml) was injected into the subserosal myometrium at three sites: the superior midpoint of the fundus, 2 cm inferiorly on the anterior wall, and 2 cm inferiorly on the posterior wall. Dye uptake into lymphatic channels was observed for 10 min. The retroperitoneal spaces were opened. Blue lymphatic channels and nodes within the pelvic and paraaortic regions were identified. Nodes demonstrating dye uptake were biopsied as separate specimens: the locations of these nodes were carefully recorded. Hysterectomy and selective lymphadenectomy were then performed as usual. RESULTS Lymphatic channels coursing into the broad ligament and along the ovarian vessels were identified from all uteri injected. Deposition of dye into grossly identifiable lymph nodes was seen in 10 of 15 cases (67%). A total of 31 nodes demonstrated dye uptake. The locations of these nodes included paraaortic sites in 12, common iliac in 6, and pelvic in 13. No dye-containing paraaortic nodes were seen below the origin of the inferior mesenteric artery. Lymphatic channels coursing above the renal vessels were seen routinely. Microscopic nodal metastases to sentinel nodes were identified in 2 of 4 women with proven lymphatic spread. CONCLUSIONS Lymphatic mapping of the uterine fundus is feasible and can identify targets for selective nodal biopsy in some women. Preliminary observations confirm that the lymphatic network draining the uterus is complex and involves both pelvic and paraaortic nodes. Lymphatic channels that parallel the ovarian vessels were not observed to enter nodes until reaching the level of the midabdomen. Further experience and refinement of techniques may lead to the development of a selective lymphadenectomy based upon direct visualization of the lymphatic drainage of the uterus rather than the current random sampling.
Carbon Sources and Dynamics in Afforested and Cultivated Corn Belt Soils

Afforestation or degrade cropland can sequester atmospheric C; however, source partitioning and turnover of soil organic C (SOC) in such ecosystems are not well documented. This study assessed SOC dynamics in two 35-yr-old, coniferous afforestation sites (i.e., a forest plantation situated in northwestern Iowa on a silty clay loam soil and a shelterbelt situated in eastern Nebraska on a silt loam soil) and the adjacent agricultural fields. Soil samples were collected at both sites to determine SOC and total N concentrations and stable C isotope ratios (δ 13 C, natural abundance) in both whole soil and the fine particulate organic matter (POM) fraction (53-500 μm size). In these fine-textured soils, afforestation of cropland performed through either shelterbelt or forest plantation caused substantial increases in surface SOC storage compared with conventionally tilled cropping systems (≥57%; P < 0.05); this confirms the direct benefits of tree planting on SOC sequestration. Relative to cropped soils, afforested soils exhibited a more depleted δ 13 C signature (-17 vs. -22%o), indicating a shift in C sources. Source-partitioning assessment revealed that tree-derived C contributed roughly half of the SOC found directly beneath the trees. The C-enriched afforested surface soils exhibited SOC turnover rates of 0.018 to 0.022 yr -1 and mean residence times of 55 to 45 yr. Fine POM in afforested surface soils accounted for a large proportion (21 %) of the existing SOC, 79% being derived from tree inputs. This supports the role of POM as a significant sink for recently sequestered SOC in these ecosystems.
Leading Deep Conversations in Collaborative Inquiry Groups

Abstract Collaborative inquiry groups, such as professional learning communities and lesson study groups, are proliferating in schools across the United States. In whatever form, the potential for impacting student learning through this collaborative work is expanded or limited by the nature of teachers’ conversations. Polite, congenial conversations remain superficially focused on sharing stories of practice, whereas collegial dialogue probes more deeply into teaching and learning. Examples of talk taken from collaborative teacher inquiry groups are used to illustrate these important differences. Specific recommendations are provided, including the role that teacher leaders can play in adopting and modeling specific strategies that support the use of more substantive professional conversation.
Exploring the Link Between Giftedness and Self-Concept

We explored three broad issues in the article. First, do gifted and nongifted children differ in their self-concepts? Second, what are the effects on the self-concept of labeling the child as gifted? Third, are there any effects on self-concept of placing a child in special programs for the gifted? The review begins with a discussion of theoretical and methodological issues associated with the self-concept and giftedness constructs. This is followed by a meta-analysis of studies bearing on the three issues. Two types of studies are reviewed: (a) cases where gifted and average students are compared in terms of the self-concept and (b) studies in which gifted children are exposed to differential programming and the effects on self-concept explored. The studies indicated generally higher academic self-concepts for gifted students, but otherwise the results of the investigations were highly variable. The article concludes with a discussion of research and practical implications.
Isolation and Potential for Transmission of Mycobacterium bovis at Human–livestock–wildlife Interface of the Serengeti Ecosystem, Northern Tanzania

Summary Mycobacterium bovis, the causative agent of bovine tuberculosis (bTB), is a multihost pathogen of public health and veterinary importance. We characterized the M. bovis isolated at the human–livestock–wildlife interface of the Serengeti ecosystem to determine the epidemiology and risk of cross‐species transmission between interacting hosts species. DNA was extracted from mycobacterial cultures obtained from sputum samples of 472 tuberculosis (TB) suspected patients and tissue samples from 606 livestock and wild animal species. M. bovis isolates were characterized using spoligotyping and Mycobacterial Interspersed Repetitive Units‐Variable Tandem Repeats (MIRU‐VNTR) on 24 loci. Only 5 M. bovis were isolated from the cultured samples. Spoligotyping results revealed that three M. bovis isolates from two buffaloes (Syncerus caffer) and 1 African civet (Civettictis civetta) belonged to SB0133 spoligotype. The two novel strains (AR1 and AR2) assigned as spoligotype SB2290 and SB2289, respectively, were identified from indigenous cattle (Bos indicus). No M. bovis was detected from patients with clinical signs consistent with TB. Of the 606 animal tissue specimens and sputa of 472 TB‐suspected patients 43 (7.09%) and 12 (2.9%), respectively, yielded non‐tuberculous mycobacteria (NTM), of which 20 isolates were M. intracellulare. No M. avium was identified. M. bovis isolates from wildlife had 45.2% and 96.8% spoligotype pattern agreement with AR1 and AR2 strains, respectively. This finding indicates that bTB infections in wild animals and cattle were epidemiologically related. Of the 24 MIRU‐VNTR loci, QUB 11b showed the highest discrimination among the M. bovis strains. The novel strains obtained in this study have not been previously reported in the area, but no clear evidence for recent cross‐species transmission of M. bovis was found between human, livestock and wild animals.
Deep Coupled Metric Learning for Cross-Modal Matching

In this paper, we propose a new deep coupled metric learning (DCML) method for cross-modal matching, which aims to match samples captured from two different modalities (e.g., texts versus images, visible versus near infrared images). Unlike existing cross-modal matching methods which learn a linear common space to reduce the modality gap, our DCML designs two feedforward neural networks which learn two sets of hierarchical nonlinear transformations (one set for each modality) to nonlinearly map samples from different modalities into a shared latent feature subspace, under which the intraclass variation is minimized and the interclass variation is maximized, and the difference of each data pair captured from two modalities of the same class is minimized, respectively. Experimental results on four different cross-modal matching datasets validate the efficacy of the proposed approach.
“You're Not Takin' Me Seriously”: Ethics and Asymmetry in Calls to a Child Protection Helpline

This article will involve comparing two calls from young people calling into the National Society for the Prevention of Cruelty to Children's (NSPCC) Helpline. Analysis draws upon two main analytical references points: discursive psychology and conversation analysis. When young people call the helpline to report abuse, one of the main activities they face is to persuade the counselors that they are reporting something illegal or at least unacceptable and ethically “wrong. ” Such interactions may establish whether a call is to be acted upon by counselors or referred to police or social services. However these types of reports by young people can lead to various types of interactional difficulties as counselors probe the motivational and epistemological status of young people's accounts. Analysis will document these troubles and show that one way of exemplifying ethical considerations is to see them as “live” issues for the participants, warranting close attention to the details of talk. The analyst's move from documenting participants' of practices to recommending strategies will also be discussed.
Corneal keratocytes: phenotypic and species differences in abundant protein expression and in vitro light-scattering.

PURPOSE Previous studies suggest that corneal haze after injury involves changes in the light-scattering properties of keratocytes that are possibly linked to the abundant expression of water-soluble proteins. The purpose of this study was to determine the protein expression pattern of keratocytes from different species and different cultured rabbit keratocyte phenotypes and to assess differences in light-scattering in vitro. METHODS Water-soluble proteins were isolated from corneal epithelial cells and keratocytes of several species, including human (Hu), mouse (Mo), rabbit (Ra), chicken (Ch), and pig (P) and different cultured rabbit keratocyte phenotypes. Proteins were then characterized by SDS-PAGE, tryptic peptide sequence analysis, and Western blot analysis. Light-scattering and actin organization from cultured cells were determined with confocal reflectance and fluorescence microscopy, respectively. RESULTS Protein expression patterns varied substantially between species and cell types, with five new abundantly expressed proteins identified including, LDH (Ra, Ch), G3PDH (Hu, Ch), pyruvate kinase (Ch), Annexin II (Ch), and protein disulfide isomerase (Ch). Different rabbit keratocyte phenotypes also showed different levels of expression of ALDH1A1 and TKT, with myofibroblasts showing the greatest reduction. Myofibroblasts showed significantly greater (P < 0.05) light-scattering but also showed the greatest organization of actin filaments. CONCLUSIONS Abundant protein expression is a characteristic feature of corneal keratocytes that is lost when cells are phenotypically modulated in culture. Greater light-scattering by myofibroblasts also provides support for a link between cellular transparency and haze after injury that is possibly related to loss of protein expression or development of prominent actin filament bundles.
Anthropometric Profile and Special Judo Fitness levels of Indian Judo Players

Purpose Judo is a complex sport where different anthropological parameters determine performance. Judo, as a sport is not well known in India. There is evident lack of data concerning the anthropological determinants of judo players. This study was conducted to determine the anthropometric profile and Special Judo Fitness levels of judokas. Methods This cross sectional study was conducted on 31 judo players. Anthropometric profile was assessed by measuring height, weight, body mass index, body circumferences at seven sites, seven site skin fold thickness and body fat percentage as per standard accepted protocol. Special Judo Fitness Test – a specific test to evaluate the judo athlete's physical condition was applied. Statistical analysis done using Student's unpaired ‘t’ test and correlation by Karl Pearson's correlation coefficient. Results Out of 31 judo players 20 had ≤5 yrs of judo practice (A group) and 11 >5 yrs of judo (B group). Anthropometric findings of both the judo groups were the same. Body fat has negative correlation (r =-0.690, P<0.05) with performance in SJFT. Observations during and after special judo fitness test were also similar. Conclusions Long term training has a minimal effect on anthropometry. Judo athletes of similar age when submitted to the same training type tend to show equal performance in the game and fitness levels after certain years of training. We also confirm existence of negative correlation between body fat and performance.
Comparison of clinical outcomes between in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in IVF-ICSI split insemination cycles

Objective This study aimed to compare the clinical outcomes between in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in sibling oocytes. Additionally, we evaluated whether the implementation of split insemination contributed to an increase in the number of ICSI procedures. Methods A total of 571 cycles in 555 couples undergoing split insemination cycles were included in this study. Among them, 512 cycles (89.7%) were a couple's first IVF cycle. The patients were under 40 years of age and at least 10 oocytes were retrieved in all cycles. Sibling oocytes were randomly allocated to IVF or ICSI. Results Total fertilization failure was significantly more common in IVF cycles than in ICSI cycles (4.0% vs. 1.4%, p<0.05), but the low fertilization rate among retrieved oocytes (as defined by fertilization rates greater than 0% but <30%) was significantly higher in ICSI cycles than in IVF cycles (17.2% vs. 11.4%, p<0.05). The fertilization rate of ICSI among injected oocytes was significantly higher than for IVF (72.3%±24.3% vs. 59.2%±25.9%, p<0.001), but the fertilization rate among retrieved oocytes was significantly higher in IVF than in ICSI (59.2%±25.9% vs. 52.1%±22.5%, p<0.001). Embryo quality before embryo transfer was not different between IVF and ICSI. Although the sperm parameters were not different between the first cycle and the second cycle, split insemination or ICSI was performed in 18 of the 95 cycles in which a second IVF cycle was performed. Conclusion The clinical outcomes did not differ between IVF and ICSI in split insemination cycles. Split insemination can decrease the risk of total fertilization failure. However, unnecessary ICSI is carried out in most split insemination cycles and the use of split insemination might make ICSI more common.
Drug utilization patterns in the emergency department: A retrospective study

Objectives: The aim of this study was to assess the prescribing trends and costs of drugs in the emergency department (ED) at Sultan Qaboos University Hospital (SQUH), a tertiary care hospital, in Muscat, the Sultanate of Oman. Materials and Methods: This was a retrospective cross-sectional study of all patients (n = 300) who attended the ED at SQUH in May 2012. Analyses were performed using descriptive and univariate statistics. Results: The average age of patients was 34 ± 19 years. The average number of drugs prescribed per patients was 3.2 ± 1.9 and the majority of the patients (n = 78; 26%) received two drugs. The most common route of drug administration was the oral route (n = 481; 51%) followed by parenterally (n = 357; 38%). Non-steroidal anti-inflammatory drugs (NSAIDs) were the most commonly prescribed class of drugs (38%) followed by the gastro-intestinal tract drugs (19%) and central nervous system drugs (13%). The average cost per prescription was 242 ± 632 US$. Morphine had the highest cost (1885 US$) followed by cefuroxime (1404 US$) and filgrastim (939 US$) over the 1-month period. There was a significant positive correlation between hospital cost and age (P < 0.001), duration of stay at the ED (P = 0.008) and emergency types (P < 0.001). Conclusion: NSAIDs were the most frequent class of drugs administered to patients. Highest number of drugs was prescribed for cardiovascular diseases followed by respiratory and gastrointestinal diseases. Anti-infective drugs cost was the highest among all other classes. The results of the present study are attempts to highlight the importance of strategies that have to be implemented to optimize medication use at the ED.
Concurrent Verbal Reports in Second Language Acquisition Research

This article provides an overview of the ways in which concurrent verbal reports, sometimes referred to as think-alouds, have been used in cognitivist second language acquisition (SLA) research. It addresses two issues related to the validity of verbal reports—reactivity and veridicality—and reviews studies that have examined the validity of verbal reports in SLA. On the basis of the results of a meta-analysis of studies comparing the performance of silent and think-aloud groups (Bowles, 2010), this article concludes with suggestions for further research into the issue of validity and recommendations for the careful use of think-alouds in research.
Adjustment and Age Through the Eyes of Portuguese and English Community- Dwelling Older Adults

Purpose: To analyze subjective age (SA) and the contributors to adjustment to aging (AtA) identified by older adults and to investigate the latent constructs that can work as major determinants in SA and AtA in an older population. Method: Measures were completed, using a variety of appropriate methods, including demographics and interviews. Complete data were available for 108 older adults aged between 75-99 years ( M = 81.1; SD = 6.43). Data was subjected to content analysis. Representation of the associations and latent constructs were analyzed by a Multiple Correspondence Analysis (MCA). Results: The most prevalent response of the interviewed participants for contributors to AtA was ‘sense of limit and existential issues’ (20.2%). ‘With congruence’ (29.3%) was identifi ed as the most frequent SA response. AtA and SA for Portuguese elderly were explained by a three-factor model: ‘integrated’, ‘involved’ and ‘youngat- heart’. A three-dimension model formed by ‘attentive’, ‘driven’ and ‘connected’ was indicated as a best-fit solution for English elderly. Conclusions: AtA is related to SA in older adults in both samples. The results presented in this paper stressed the under-developed potential of an adjustment and age overall model for this population. Key words : Adjustment to Aging; English; Portuguese; Multiple correspondence analysis; Community-dwelling older adults; Subjective age