Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Evaluation and Finite Element Simulation to Produce Square Cup by Deep Drawing Process

Deep drawing process to produce square cup is very complex process due to a lot of process parameters which control on this process, therefore associated with it many of defects such as earing, wrinkling and fracture. Study of the effect of some process parameters to determine the values of these parameters which give the best result, the distributions for the thickness and depths of the cup were used to estimate the effect of the parameters on the cup numerically, in addition to experimental verification just to the conditions which give the best numerical predictions in order to reduce the time, efforts and costs for producing square cup with less defects experimentally is the aim of this study. The numerical analysis is used to study the effect of some parameters such as die profile radius, radial clearance between die and punch, blank diameter on the length and thickness distributions on the cup, dynamic-explicit (ANSYS11) code based on finite element method is utilized to simulate the square deep drawing operation. Experiments were done for comparison and verification the numerical predictions. effective square cup with less defects and acceptable thickness distributions were produced in this study. It is concluded the most thinning appear in the corner cup due to excessive stretching occur in this region and also it is found the cup thickness and height prediction by numerical analysis and in general in harmony with experimental analysis.
Quantitative assessment of olfactory experience during pregnancy.

&NA; Results of the National Geographic Smell Survey were used to investigate the effects of pregnancy on olfactory perception and odor‐related behavior. The responses to test odors and survey questions of 13,610 pregnant and 277,228 nonpregnant U.S. women between 20 and 40 years of age were analyzed. In comparison to nonpregnant women, pregnant women rated their own sense of smell lower, more often rated the test odors less pleasant smelling, more often classified the test odors as inedible, were less likely to report odor‐evoked memories, and used perfume and cologne less frequently. Differences in odor detection and intensity rating did not favor either group.
A Self-study of Listening to Student Voice in two University Early Childhood Degree Programs

Early childhood educators' own experiences of being listened to and of developing their own voice is likely to give them insight into what it means to be a listener in professional practice. Universities, students and staff can learn much from incorporating processes to encourage pre-service teaching students to engage in dialogue with lecturers and their peers about learning and teaching in a way that contributes to the program, while building student and staff capacity (Martin & Russell 2005). Using a self-study approach (Russell 1998), the author described and interrogated her journey as a listening educator, and the processes she and other staff teaching in early childhood programs used to engage students in dialogue about their programs. Key ideas from relevant literature were used in this process (Clark 2005; Freire 1975; Moss 2008; Rinaldi 2006). The aim of the study was to investigate the author's own practices of listening to student voices to inform her teaching, building a foundation for personal, professional and program improvement. Four challenges are identified: considering power relations, understanding the terms listening and voice, handling the content of feedback, and making the process dialogic. Ideas are proposed for improving the feedback processes using participatory methods (Searle 2010).
New Mexico pharmacists' knowledge, attitudes, and beliefs toward prescribing oral emergency contraception.

OBJECTIVE To describe New Mexico pharmacists' knowledge, attitudes, and beliefs toward the prescribing of oral emergency contraception (EC) in their practices. DESIGN Cross-sectional study. SETTING New Mexico in January through March 2004. POTENTIAL PARTICIPANTS: New Mexico pharmacists. INTERVENTIONS Questionnaire containing 74 items. MAIN OUTCOME MEASURE(S) Mean scores were calculated for individual knowledge items, overall knowledge scores, and attitude/belief items. Knowledge and attitude/belief scores were compared across demographic variables using t tests, ANOVA, and chi-square analyses. RESULTS Of 1392 deliverable questionnaires, 555 (40%) were returned and 523 (38%) were usable; 136 contained written comments. Pharmacists had overall knowledge scores of 71.2% +/- 11.3%. Pharmacists who had participated in a state-approved EC prescribing training program and had time in their practice setting to prescribe EC had significantly higher knowledge scores. Mean scores indicated that pharmacists have positive attitudes and beliefs toward prescribing EC. Overall, 40% of respondents indicated that they would like to become certified to prescribe EC. Pharmacists who agreed that they would like to be certified to prescribe EC were significantly more likely to be male, non-Hispanic, non-Christian, to have liberal or moderate political views, and to indicate that they had employer/manager approval, time, and privacy in their practice setting to prescribe EC. CONCLUSION New Mexico pharmacists have positive attitudes/beliefs toward EC prescribing; however, their knowledge in this area is average. Although religious, moral, and political views influence pharmacists' willingness to prescribe EC, factors such as education and practice environment must be addressed if more pharmacists are to accept this EC prescriptive authority.
Model for Delay Faults Based upon Paths

Delay testing of combinational logic in a clocked environment is analyzed. A model based upon paths is introduced for delay faults. Any path with a total delay exceeding the clock interval is called a "path fault. " This is a global delay fault model because it is associated with an entire path. The more familiar slow-to-rise or slow-to-fall gate delay fault, on the other hand, is a local fault model. A procedure is described which identifies paths which are tested for path faults by a set of patterns. It does not involve delay simulation. The paths so identified are tested for path faults independent of the delays of any individual gate of the network.
Reafferent copies of imitated actions in the right superior temporal cortex

Imitation is a complex phenomenon, the neural mechanisms of which are still largely unknown. When individuals imitate an action that already is present in their motor repertoire, a mechanism matching the observed action onto an internal motor representation of that action should suffice for the purpose. When one has to copy a new action, however, or to adjust an action present in one's motor repertoire to a different observed action, an additional mechanism is needed that allows the observer to compare the action made by another individual with the sensory consequences of the same action made by himself. Previous experiments have shown that a mechanism that directly matches observed actions on their motor counterparts exists in the premotor cortex of monkeys and humans. Here we report the results of functional magnetic resonance experiments, suggesting that in the superior temporal sulcus, a higher order visual region, there is a sector that becomes active both during hand action observation and during imitation even in the absence of direct vision of the imitator's hand. The motor-related activity is greater during imitation than during control motor tasks. This newly identified region has all the requisites for being the region at which the observed actions, and the reafferent motor-related copies of actions made by the imitator, interact.
Twenty-Four Months Follow-Up of Intravitreal Bevacizumab Injection Versus Intravitreal Triamcinolone Acetonide Injection for the Management of Persistent Non-Infectious Uveitic Cystoid Macular Edema

ABSTRACT Purpose: To report the efficacy of intravitreal bevacizumab (IVB) injection versus intravitreal triamcinolone acetonide (IVT) for persistent non-infectious uveitic cystoid macular edema (CME). Methods: Interventional retrospective comparative case series evaluated 37 consecutive patients (44 eyes) with completely controlled uveitis and recalcitrant CME. Patients received repeated injections of 1.25 mg of IVB or 4 mg of IVT. Results: Best-corrected visual acuity (BCVA) at baseline and 24 months was logMAR 1 and 0.8 respectively, in the IVB group (p = 0.002) and; logMAR of 1.1 and 0.6, in the IVT group (p = 0.001). Central macular thickness at baseline and 24 months was 399.2 µm and 333.7 µm (p < 0.0009), respectively, for the IVB group and; 464.4 µm and 316.5 µm in the IVT group (p = 0.044). Postoperatively, IOP increased in the IVT group. Conclusions: Repeated injections with IVT improve BCVA as effectively as repeated injections with IVB in the long-term management of persistent uveitic CME.
Science, Technology, and Sexual Offending

examples of such sharing. That is why articles such as those by Studer and Reddon in this issue shine as brightly as Venus on a moonless summer’s night. These authors examine a simple premise: Does treatment change risk prediction? Their results, taken together with those of Proulx et al. (1997) and Hanson (1997), indicate that something in the right direction is happening in cognitive/behavioral treatment programs for sexual offenders.
APRI: a simple bedside marker for advanced fibrosis that can avoid liver biopsy in patients with NAFLD/NASH.

BACKGROUND Non-alcoholic steatohepatitis (NASH) can lead to cirrhosis and hepatocellular carcinoma. The NASH fibrosis score (NFS) has proven to be a reliable, non-invasive marker for prediction of advanced fibrosis. Aspartate aminotransferase-to-platelet ratio index (APRI) is a simpler calculation than NFS, but has never been studied in patients with non-alcoholic fatty liver disease (NAFLD). AIM To validate APRI as a non-invasive marker of liver fibrosis in subjects with NAFLD to be used in clinical practice. DESIGN/METHODS The cohort consisted of 111 patients with histological diagnoses of NAFLD. The biopsy samples were staged and graded according to the NASH clinical research network (CRN) criteria. These were grouped into fatty liver disease (FLD), NASH, no/mild fibrosis, and advanced fibrosis. The sensitivity and specificity of APRI were compared with NFS and aspartate aminotransferase-to-alanine aminotransferase (AST/ALT) ratio. RESULTS The APRI was significantly higher in the advanced fibrosis group. The area under receiver operating characteristic (ROC) curve for APRI was 0.85 with an optimal cut-off of 0.98, giving a sensitivity of 75% and a specificity of 86%. The NFS was significantly lower in the advanced fibrosis group. The ROC for NFS gave an area under curve (AUC) of 0.77 and a cut-off value of -1.3 with a sensitivity of 76% and specificity of 69%. The positive predictive value for APRI was 54% as opposed to 34% for NFS. The negative predictive value was 93% for APRI and 94% for NFS. CONCLUSION APRI compared favourably to NFS and was superior to AST/ALT for the prediction of advanced fibrosis. We therefore propose the use of APRI in a new algorithm for the detection of advanced fibrosis.
Volunteer Tourism and Intercultural Sensitivity: The Role of Interaction with Host Communities

ABSTRACT This research introduced the concept of intercultural sensitivity to investigate the relationships between the context of volunteer tourism and the change in intercultural sensitivity, empirically assessing the supposition that volunteer tourism facilitates cross-cultural understanding. As a theoretical backdrop, the study utilized Developmental Model of Intercultural Sensitivity (DMIS) postulating that one’s journey towards greater intercultural sensitivity consists of six consecutive stages along the enthnocentrism–ethnorelativism continuum. Canonical correlation analysis of the survey data revealed that quality of interaction with the host community was the most significant predictor of change in intercultural sensitivity. Additionally, this study demonstrated that volunteer tourism is linked to positive and negative changes in intercultural sensitivity and therefore has the potential to simultaneously promote and inhibit cross-cultural understanding.
PRELIMINARY ANALYSIS OF FUNCTIONS OF THE TEMPORAL LOBES IN MONKEYS

In previous communications1we pointed out that the chief symptoms following bilateral temporal lobectomy in the rhesus monkey consist in "psychic blindness" (Seelenblindheit) or visual agnosia, strong "oral" tendencies and profound emotional changes. Our results were primarily based on an analysis of the behavioral symptoms of a female rhesus monkey which had been studied for a period of four months following the operations. The type of disturbance analyzed in that case seemed to be similar to the "associative mind blindness" of Lissauer.2It is true that the diagnosis "agnosia" can be only of practical importance and merely serves to raise a number of questions. A review of the clinical literature indicates that the more carefully a case is studied the more difficult it may be to decide whether there is really an "agnostic" or merely a "visual" defect, that is, whether the variety of "agnostic" symptoms can be
Elevated intraocular pressure, optic nerve atrophy, and impaired retinal development in ODAG transgenic mice.

PURPOSE In an earlier study, a cDNA was cloned that showed abundant expression in the eye at postnatal day (P)2 but was downregulated at P10; it was named ODAG (ocular development-associated gene). Its biological function was examined by generating and analyzing transgenic mice overexpressing ODAG (ODAG Tg) in the eye and by identifying ODAG-binding proteins. METHODS Transgenic mice were generated by using the mouse Crx promoter. EGFP was designed to be coexpressed with transgenic ODAG, to identify transgene-expressing cells. Overexpression of ODAG was confirmed by Northern and Western blot analysis. IOP was measured with a microneedle technique. The eyes were macroscopically examined and histologically analyzed. EGFP expression was detected by confocal microscope. Proteins associated with ODAG were isolated by pull-down assay in conjugation with mass spectrometry. RESULTS Macroscopically, ODAG Tg exhibited gradual protrusion of the eyeballs. The mean IOP of ODAG Tg was significantly higher than that of wild-type (WT) littermates. Histologic analysis exhibited optic nerve atrophy and impaired retinal development in the ODAG Tg eye. EGFP was expressed highly in the presumptive outer nuclear layer and weakly in the presumptive inner nuclear layer in the ODAG Tg retina. Rab6-GTPase-activating protein (Rab6-GAP) and its substrate, Rab6, were identified as ODAG-binding proteins. CONCLUSIONS Deregulated expression of ODAG in the eye induces elevated intraocular pressure and optic nerve atrophy and impairs retinal development, possibly by interfering with the Rab6/Rab6-GAP-mediated signaling pathway. These results provide new insights into the mechanisms regulating ocular development, and ODAG Tg would be a novel animal model for human diseases caused by ocular hypertension.
Protein Kinase C Phosphomimetics Alter Thin Filament Ca2+ Binding Properties

Adrenergic stimulation modulates cardiac function by altering the phosphorylation status of several cardiac proteins. The Troponin complex, which is the Ca2+ sensor for cardiac contraction, is a hot spot for adrenergic phosphorylation. While the effect of β-adrenergic related PKA phosphorylation of troponin I at Ser23/24 is well established, the effects of α-adrenergic induced PKC phosphorylation on multiple sites of TnI (Ser43/45, Thr144) and TnT (Thr194, Ser198, Thr203 and Thr284) are much less clear. By utilizing an IAANS labeled fluorescent troponin C, , we systematically examined the site specific effects of PKC phosphomimetic mutants of TnI and TnT on TnC’s Ca2+ binding properties in the Tn complex and reconstituted thin filament. The majority of the phosphomemetics had little effect on the Ca2+ binding properties of the isolated Tn complex. However, when incorporated into the thin filament, the phosphomimetics typically altered thin filament Ca2+ sensitivity in a way consistent with their respective effects on Ca2+ sensitivity of skinned muscle preparations. The altered Ca2+ sensitivity could be generally explained by a change in Ca2+ dissociation rates. Within TnI, phosphomimetic Asp and Glu did not always behave similar, nor were Ala mutations (used to mimic non-phosphorylatable states) benign to Ca2+ binding. Our results suggest that Troponin may act as a hub on the thin filament, sensing physiological stimuli to modulate the contractile performance of the heart.
Eating disturbances in adolescent girls: (a review).

This review examines eating disturbances in adolescent girls, the predisposing causes and medical complications that are related to these disturbances. The keywords, eating disorders, body dissatisfaction, medical complications and risk factors of eating disorders were used in the electronic database. Articles addressing these issues were selected for reviewing. Adolescent girls are preoccupied with their body weight and shape because of pubertal changes, social and cultural norms as well. This preoccupation has initiated eating and body image disturbances. Interventional methods addressing eating disorders in adolescent girls are needed, which should focus on both, behavioral and environmental changes.
Graphene Oxide Nanoribbons Induce Autophagic Vacuoles in Neuroblastoma Cell Lines

Since graphene nanoparticles are attracting increasing interest in relation to medical applications, it is important to understand their potential effects on humans. In the present study, we prepared graphene oxide (GO) nanoribbons by oxidative unzipping of single-wall carbon nanotubes (SWCNTs) and analyzed their toxicity in two human neuroblastoma cell lines. Neuroblastoma is the most common solid neoplasia in children. The hallmark of these tumors is the high number of different clinical variables, ranging from highly metastatic, rapid progression and resistance to therapy to spontaneous regression or change into benign ganglioneuromas. Patients with neuroblastoma are grouped into different risk groups that are characterized by different prognosis and different clinical behavior. Relapse and mortality in high risk patients is very high in spite of new advances in chemotherapy. Cell lines, obtained from neuroblastomas have different genotypic and phenotypic features. The cell lines SK-N-BE(2) and SH-SY5Y have different genetic mutations and tumorigenicity. Cells were exposed to low doses of GO for different times in order to investigate whether GO was a good vehicle for biological molecules delivering individualized therapy. Cytotoxicity in both cell lines was studied by measuring cellular oxidative stress (ROS), mitochondria membrane potential, expression of lysosomial proteins and cell growth. GO uptake and cytoplasmic distribution of particles were studied by Transmission Electron Microscopy (TEM) for up to 72 h. The results show that GO at low concentrations increased ROS production and induced autophagy in both neuroblastoma cell lines within a few hours of exposure, events that, however, are not followed by growth arrest or death. For this reason, we suggest that the GO nanoparticle can be used for therapeutic delivery to the brain tissue with minimal effects on healthy cells.
Probabilistic

Typical address-oriented computer memories cannot recognize incomplete or noisy information. Associative (content-addressable) memories solve this problem but suﬀer from severe capacity shortages. I propose a model of a quantum memory that solves both problems. The storage capacity is exponential in the number of qbits and thus optimal. The retrieval mechanism for incomplete or noisy inputs is probabilistic, with postselection of the measurement result. The output is determined by a probability distribution on the memory which is peaked around the stored patterns closest in Hamming distance to the input.
Incorporating Ethnic-Specific Measures of Immigration in the Study of Lethal Violence

The growing body of research on immigration and crime consistently finds that immigration, contrary to both criminological theory and popular sentiment, is not related to higher levels of lethal violence. Instead, a common finding in the literature is that immigration predicts lower levels of violence, and homicide in particular. The primary objective of the present study is an initial test of hypotheses associated with the Latino paradox, by focusing on the degree to which the impact of immigration operates differentially as a product of ethnicity. Using neighborhood-level homicide data and ethnically disaggregated indicators of immigration, these are consistent with the expectations of the Latino paradox.
An Evaluation of Two Types of Cognitive Intervention in the Management of Chronic Tinnitus

Abstract Fifty-four subjects with chronic distressing tinnitus were randomly allocated to one of four experimental treatment conditions: (1) attention control and imagery training (AC1); (2) cognitive restructuring (CR); (3) combined attention control and imagery training plus cognitive restructuring (ACI + CR); and (4) a waiting list control (WLC). Significant overall improvements were found on measures of distress associated with tinnitus, and on a number of other measures of cognition and coping strategies. These improvements were maintained at the six-month follow-up. Relative to the WLC, the three treatment conditions (combined) were associated with improvements in tinnitus-related distress, reductions in tinnitus-related dysfunctional cognitions and an increase in the frequency of use of coping strategies. There was a significant effect in favour of the ACI group compared to the CR group on the measure of irrational beliefs. The analyses also revealed that the combined treatment condition (ACI + CR).
The Characteristics of Dielectric Barrier Discharge Plasma Under the Effect of Parallel Magnetic Field

The dielectric barrier discharge plasma (DBDP) has been produced by the dielectric barrier discharge (DBD) reactor that has been established to operate at atmospheric pressure. DBD reactor consists of two parallel metal electrodes, one is a high-voltage (HV) electrode with a circular iron plate shape and the other is a rectangular steel plate, and the ground electrode with a dielectric material covered one of them. The ac power supply has been used to provide the DBD circuit with ac voltage up to 15kV peak value, 50 Hz. The dielectric material used, which covered one reactor electrode, is a glass slab. The gap distance of the discharge is fixed at 3 mm. Argon (Ar) and air gases have been used in the experiment at 20SCFH (standard cubic foot per hour) flow rate, and a sinusoidal voltage is applied to the electrodes to generate a homogenous DBDP. The parameters of the discharge such as discharge current, discharge voltage, consumed power of discharge, streamer filament, and emitted plasma light have been studied. A magnetic field, with the direction parallel to the electric field, is applied to the ac and DBD, using Ar and helium (He) gases. The effect of the parallel magnetic field for generating the DBDP has been investigated. It indicates that the discharge current in the antiparallel magnetic field is lower than that without the magnetic field. Also, the DBDP in the magnetic field is more luminous than that without the magnetic field. It further indicates that the area of Lissajous figure of the DBD in the presence of antiparallel magnetic field is little reduced than that without the magnetic field. It could be concluded that the effect of the magnetic field influenced DBDP progress.