Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence of High-Risk Cervical Human Papillomavirus and Squamous Intraepithelial Lesion in Nigeria

Objective The prevalence of cervical cancer and high-risk human papillomavirus (HPV) in Nigerian women remains poorly studied. Our objective was to estimate the prevalence of high-risk HPV and associated squamous intraepithelial lesions (SILs) in Nigeria. Methods After institutional review board approval, data collection was performed by volunteers of FaithCare, Inc, between 2004 and 2008 in 3 regions of Nigeria (Okene, Katari, and Abuja). Demographic data and ThinPrep Pap smears (Cytyc, Marlborough, MA) were collected from 410 women. Pap smears were analyzed for both the presence of SIL and HPV DNA. Results The prevalence of high-risk HPV and SIL was 15.6% and 6.8%, respectively. Of the 28 abnormal Pap tests, 42.9% had atypical squamous cells of undetermined significance, 39.3% had low-grade SIL, 14.3% had high-grade SIL, and 3.6% had atypical glandular cells. There was a strong association between high-risk HPV and SIL in both the combined (p < .001) and individual group data (p < .001, p = .013, and p < .001 for Okene, Abuja, and Katari, respectively). However, there were no statistically significant correlations between either high-risk HPV or presence of SIL and known risk factors including age, history of sexually transmitted disease, and the number of sexual partners. There was also no statistical difference in the prevalence of high-risk HPV and SIL among the 3 locations. Conclusions A strong association exists between high-risk HPV and SIL. The prevalence of cervical high-risk HPV and SIL, however, did not vary in the 3 different locations and is consistent with reports from other regions in Africa.
A prospective study of child maltreatment and self-injurious behavior in a community sample

Abstract In conjunction with prospective ratings of child maltreatment (i.e., sexual abuse, physical abuse, and physical neglect) and measures of dissociation and somatization, this study examined prospective pathways between child maltreatment and nonsuicidal, direct self-injurious behavior (SIB; e.g., cutting, burning, self-hitting). Ongoing participants in the Minnesota Longitudinal Study of Parents and Children (N = 164; 83 males, 81 females) completed a semistructured interview about SIB when they were 26 years old. SIB emerged as a heterogeneous and prominent phenomenon in this low-income, mixed-gender, community sample. Child sexual abuse predicted recurrent injuring (i.e., three or more events; n = 13), whereas child physical abuse appeared more salient for intermittent injuring (i.e., one to two events; n = 13). Moreover, these relations appeared largely independent of risk factors that have been associated with child maltreatment and/or SIB, including child cognitive ability, socioeconomic status, maternal life stress, familial disruption, and childhood exposure to partner violence. Dissociation and somatization were related to SIB and, to a lesser degree, child maltreatment. However, only dissociation emerged as a significant mediator of the observed relation between child sexual abuse and recurrent SIB. The findings are discussed within a developmental psychopathology framework in which SIB is viewed as a compensatory regulatory strategy in posttraumatic adaptation.
Handbook of Measurement Issues in Family Research

Contents: Preface. Part I: Introduction. L.M. Casper, S.L. Hofferth, Playing Catch-Up: Improving Data and Measures for Family Research. Part II: Marriage and Cohabitation. J.T. Knab, S. McLanahan, Measuring Cohabitation: Does How, When, and Who You Ask Matter? M.S. Pollard, K.M. Harris, Measuring Cohabitation in Add Health. P.R. Amato, Studying Marriage and Commitment With Survey Data. A.J. Hawkins, B.J. Fowers, J.S. Carroll, C. Yang, Conceptualizing and Measuring Marital Virtues. S.M. Stanley, Assessing Couple and Marital Relationships: Beyond Form and Toward a Deeper Knowledge of Function. K.A. Moore, J. Bronte-Tinkew, S. Jekielek, L. Guzman, S. Ryan, Z. Redd, J. Carrano, G. Matthews, Developing Measures of Healthy Marriages and Relationships. Part III: Separation and Divorce. L. Bumpass, K. Raley, Measuring Separation and Divorce. M. O'Connell, The Visible Hand: Editing Marital-History Data From Census Bureau Surveys. Part IV: Household Composition and Family Relationships. P.D. Brandon, Mapping Children's Living Arrangements With a Relationship Matrix. M. Hill, P. Callister, Is Single-Parent Family a Misnomer Misdirecting Research and Policies? W.D. Manning, R.E. Bulanda, Cohabitation and Measurement of Family Trajectories. J. Iceland, Measuring Poverty With Different Units of Analysis. G.J. Gates, R. Sell, Measuring Gay and Lesbian Couples. W.D. Mosher, Including the Military and the Incarcerated in Surveys of Families. Part V: Becoming a Father. F.L. Mott, D.S. Hurst, T. Gryn, Male Relationship and Fertility Data in the NLSY. S. Boggess, G. Martinez, C.B. Jasik, L.D. Lindberg, Counting Dads: Improving Estimates of Teen Fatherhood. W. Marsiglio, Qualitative Insights for Studying Male Fertility. C. Bachrach, Taking Stock: Do Surveys of Men's Fertility Deliver? Part VI: Fathers and Fathering. S.L. Hofferth, N. Cabrera, M. Carlson, R.L. Coley, R. Day, H. Schindler, Resident Father Involvement and Social Fathering. L. Argys, E. Peters, S. Cook, S. Garasky, L. Nepomnyaschy, E. Sorensen, Measuring Contact Between Children and Nonresident Fathers. S. Garasky, E. Peters, L. Argys, S. Cook, L. Nepomnyaschy, E. Sorensen, Measuring Support to Children by Nonresident Fathers. Part VII: Conclusion. S.L. Hofferth, L.M. Casper, Progress Made, Gaps Remain: Final Observations.
Depressive Symptoms and Risks of Coronary Heart Disease and Mortality in Elderly Americans

BackgroundSeveral epidemiological studies have associated depressive symptoms with cardiovascular disease. We investigated whether depressive symptoms constituted a risk for coronary heart disease (CHD) and total mortality among an apparently healthy elderly cohort. Methods and ResultsIn a prospective cohort of 5888 elderly Americans (≥65 years) who were enrolled in the Cardiovascular Health Study, 4493 participants who were free of cardiovascular disease at baseline provided annual information on their depressive status, which was assessed using the Depression Scale of the Center for Epidemiological Studies. These 4493 subjects were followed for 6 years for the development of CHD and mortality. The cumulative mean depression score was assessed for each participant up to the time of event (maximum 6-year follow-up). Using time-dependent, proportional-hazards models, the unadjusted hazard ratio associated with every 5-unit increase in mean depression score for the development of CHD was 1.15 (P =0.006); the ratio for all-cause mortality was 1.29 (P <0.0001). In multivariate analyses adjusted for age, race, sex, education, diabetes, hypertension, cigarette smoking, total cholesterol, triglyceride level, congestive heart failure, and physical inactivity, the hazard ratio for CHD was 1.15 (P =0.006) and that for all-cause mortality was 1.16 (P =0.006). Among participants with the highest cumulative mean depression scores, the risk of CHD increased by 40% and risk of death by 60% compared with those who had the lowest mean scores. ConclusionsAmong elderly Americans, depressive symptoms constitute an independent risk factor for the development of CHD and total mortality.
The Theory of Cultural and Social Selection

Preface Prologue. The Darwinian legacy 1. The neo-Darwinian paradigm 2. Natural selection and evoked behaviour 3. Cultural selection and acquired behaviour 4. Social selection and imposed behaviour 5. Selectionist theory as narrative history Epilogue. Sociology in a post-Darwinian world.
Professional training as a strategy for staff development: A study in training transfer in the Lebanese context

Purpose – Research studies on training‐job relevance continuously discuss the extent of transfer being found limited. This study aims to focus on exploring trainees' perceptions about the effects of a “Western” professional training program on their skill development and how cultural factors specific to Lebanon influence the learning.Design/methodology/approach – This research adopted a mixed method study design. It was conducted in the context of a training services program offered by an HRD department in a large Lebanese financial institution. The sample frame consisted of service employees who were conveniently selected after enrolling in the professional training program. The sample was composed of 120 participants. A total number of 107 questionnaires were completed and 101 questionnaires were usable (82.5 percent response rate). Analysis of the quantitative data was through descriptive statistics. Qualitative data collection was included to corroborate the quantitative data in answering the research.
Diagnosis of Langerhans Cell Histiocytosis on Fine Needle Aspiration Cytology: A Case Report and Review of the Cytology Literature

A case of multifocal Langerhans cell histiocytosis in a two-year-old child is presented where fine needle aspiration was helpful in achieving a rapid and accurate diagnosis in an appropriate clinical and radiological setting. This can avoid unnecessary biopsy and guide the management especially where access to histopathology is limited. The highly characteristic common and rare cytological features are highlighted with focus on differential diagnoses and causes of pitfalls.
Increased risk for ischaemic events is related to combined RAS polymorphism

OBJECTIVE To determine whether the angiotensin converting enzyme (ACE) and the angiotensin II type 1 receptor (AT1R A1166C) gene polymorphism interact to increase the risk of ischaemic events, and whether this can be explained by the progression of angiographically defined coronary atherosclerosis. DESIGN Prospective defined substudy of the lipid lowering regression trial (REGRESS). SETTING University hospital. PATIENTS 885 male patients with stable coronary artery disease. MAIN OUTCOME MEASURES Incidence of ischaemic events during a two year follow up; serial quantitative coronary arteriography (mean segment diameter and minimum obstruction diameter) at baseline and after two years. RESULTS Patients who carried both the ACE-DD and AT1R-CC genotype had significantly more ischaemic events during the two year follow up than those carrying other genotype combinations (p = 0.035, Mantel-Haenszel test for linear association). There was no association between the two genotypes and mean segment diameter or minimum obstruction diameter at baseline or after two years. CONCLUSIONS The suggestion that ACE-DD and AT1R-CC genotypes interact to increase the risk of ischaemic events is confirmed. However, this increased risk was not accompanied by increased progression of angiographically defined coronary atherosclerosis.
Platelet Aggregability, Disaggregability and Serotonin Uptake in Migraine

Several disturbances in platelet function have been reported in migraineurs including serotonin (5–HT) metabolism and abnormal aggregability of platelets. The present work compared platelets taken from migraineurs during attacks and at headache-free periods with those of controls. The results demonstrated a tendency to increased aggregability during attacks compared to headache-free periods, and lower still in controls. Kinetic analysis of 5–HT uptake revealed normal K, increased V values and lower imipramine inhibition in m max migraineurs (both during headache and at headache-free periods). However, although the differences were significant statistically, they were small, and their clinical relevance remains to be proven.
Pentacoordinate and Hexacoordinate Mn(III) Complexes of Tetradentate Schiff-Base Ligands Containing Tetracyanidoplatinate(II) Bridges and Revealing Uniaxial Magnetic Anisotropy

Crystal structures and magnetic properties of polymeric and trinuclear heterobimetallic MnIII···PtII···MnIII coordination compounds, prepared from the Ba[Pt(CN)4] and [Mn(L4A/B)(Cl)] (1a/b) precursor complexes, are reported. The polymeric complex [{Mn(L4A)}2{μ4-Pt(CN)4}]n (2a), where H2L4A = N,N’-ethylene-bis(salicylideneiminate), comprises the {Mn(L4A)} moieties covalently connected through the [Pt(CN)4]2− bridges, thus forming a square-grid polymeric structure with the hexacoordinate MnIII atoms. The trinuclear complex [{Mn(L4B)}2{μ-Pt(CN)4}] (2b), where H2L4B = N,N’-benzene-bis(4-aminodiethylene-salicylideneiminate), consists of two [{Mn(L4B)} moieties, involving pentacoordinate MnIII atoms, bridged through the tetracyanidoplatinate (II) bridges to which they are coordinated in a trans fashion. Both complexes possess uniaxial type of magnetic anisotropy, with D (the axial parameter of zero-field splitting) = −3.7(1) in 2a and −2.2(1) cm−1 in 2b. Furthermore, the parameters of magnetic anisotropy 2a and 2b were also thoroughly studied by theoretical complete active space self-consistent field (CASSCF) methods, which revealed that the former is much more sensitive to the ligand field strength of the axial ligands.
Mathematical basis of affected sib-pair analysis: an extension to X-linked loci

Most clinical genetic studies are done without knowing their mathematical basis. However, because the results of such studies rely on the correctness of the mathematical calculations involved, we cannot ignore the mathematics of genetic studies. In this study, the mathematical basis of the sib-pair method, which has been widely used in recent genome-wide studies, was extended to studies focusing on the X chromosome, and then applied to study a clinical microsatellite marker on the X chromosome. Our calculation involves classifying marker types on the X chromosome for an affected sib-pair and an unaffected sib, together with their sexual information and the possible parental marker types applicable to a genome-wide genetic study. The method proposed in this study was then applied to 41 Japanese rheumatoid families, and the locus DXS984 was found to be most likely to be linked with rheumatoid arthritis (RA). This locus, which we found nicely, was also highlighted in a previous study that used the Mapmaker/sibs program, so we can conclude that our calculation provides a solid foundation for understanding and confirming the results obtained using the sib-pair method.
Deadline Differentiated Pricing of Deferrable Electric Loads

A large fraction of total electricity demand is comprised of end-use devices whose demand for energy is inherently deferrable in time. Of interest is the potential to use this latent flexibility in demand to absorb variability in power supplied from intermittent renewable generation. A fundamental challenge lies in the design of incentives that induce the desired response in demand. With an eye to electric vehicle charging, we propose a novel forward market for deadline-differentiated electric power service, where consumers consent to deferred service of prespecified loads in exchange for a reduced price for energy. The longer a consumer is willing to defer, the lower the price for energy. The proposed forward contract provides a guarantee on the aggregate quantity of energy to be delivered by a consumer-specified deadline. Under the earliest-deadline-first (EDF) scheduling policy, which is shown to be optimal for the supplier, we explicitly characterize a non-discriminatory, deadline-differentiated pricing scheme that yields an efficient competitive equilibrium between the supplier and consumers. We further show that this efficient pricing scheme, in combination with EDF scheduling, is incentive compatible in that every consumer would like to reveal her true deadline to the supplier, regardless of the actions taken by other consumers.
Deposit Insurance and Bank Risk-Taking: Evidence from Internal Loan Ratings

We analyze the effect of deposit insurance on the risk-taking behavior of banks in the context of a quasi-natural experiment using detailed credit registry data. Using the case of an emerging economy, Bolivia, which introduced a deposit insurance system during the sample period, we compare the risk-taking behavior of banks before and after the introduction of this system. We find that in the post-deposit insurance period, banks are more likely to initiate riskier loans (i.e., loans with worse internal ratings at origination). These loans carry higher interest rates and are associated with worse ex-post performance (i.e., they have higher default and delinquency rates). Banks do not seem to compensate for the extra risk by increasing collateral requirements or decreasing loan maturities. We also find evidence that the increase in risk-taking is due to the decrease in market discipline from large depositors. Finally, differences between large (too-big-to-fail) and small banks diminished in the post-deposit insurance period.
Optimal Strategies of the Iterated Prisoner's Dilemma Problem for Multiple Conflicting Objectives

In this paper, we present a new paradigm of searching optimal strategies in the game of iterated prisoner's dilemma (IPD) using multiple-objective evolutionary algorithms. This method is more useful than the existing approaches, because it not only produces strategies that perform better in the iterated game but also finds a family of nondominated strategies, which can be analyzed to decipher properties a strategy should have to win the game in a more satisfactory manner. We present the results obtained by this new method and discuss sub-strategies found to be common among nondominated strategies. The multiobjective treatment of the IPD problem demonstrated here can be applied to other similar game-playing tasks.
Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials.

BACKGROUND The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) are widely used for the treatment of hyperlipidemia, and recent in vitro and animal data suggest that statins promote bone formation and increase bone strength. METHODS To determine whether statin use is associated with a reduced risk for fracture, we analyzed statin use and fracture rates in 4 large prospective studies (the Study of Osteoporotic Fractures, the Fracture Intervention Trial, the Heart and Estrogen/Progestin Replacement Study, and the Rotterdam Study). We searched MEDLINE through January 2002 and abstracts from major scientific meetings and performed a cumulative meta-analysis of published and unpublished observational studies and clinical trials. The meta-analysis included 8 observational studies and 2 clinical trials that reported statin use and documented fracture outcomes. RESULTS After adjustment for multiple factors, including age, body mass index, and estrogen use, we found a trend toward fewer hip fractures (relative hazards [RHs], 0.19-0.62) and, to a lesser extent, nonspine fractures (RHs, 0.49-0.95) among statin users in each of the 4 prospective studies. The meta-analysis of observational studies was consistent with these findings. The summary odds ratio (OR) for statin use and hip fracture was 0.43 (95% confidence interval [CI], 0.25-0.75), whereas that for nonspine fracture was 0.69 (95% CI, 0.55-0.88). The meta-analysis of clinical trial results did not support a protective effect with statin use for hip fracture (summary OR, 0.87; 95% CI, 0.48-1.58) or nonspine fracture (OR, 1.02; 95% CI, 0.83-1.26). CONCLUSIONS Observational studies suggest that the risk for hip and nonspine fractures is lower among older women taking statin medications for hyperlipidemia, but post hoc analyses of cardiovascular trials do not. Controlled trials specifically designed to test the effect of statins on skeletal metabolism and fracture are needed.
Stochastic Frontier Analysis of Hospital Inefficiency

Twenty stochastic frontier analysis (SFA) studies of hospital inefficiency in the United States were analyzed. Results from best-practice methods were compared against previously used methods in hospital studies to ascertain the robustness of SFA in estimating cost inefficiency. To compare past studies and analyze new data, SFA methods were varied by (a) the assumptions of the structure of costs and distribution of the error term, (b) inclusion of quality and product descriptor measures, and (c) use of simultaneous and two-stage estimation techniques. SFA results were relatively insensitive to several model variations.
The Sociological Problem of Generations

The problem of generations is important enough to merit serious consideration. It is one of the indispensable guides to an understanding of the structure of social and intellectual movements. Its practical importance becomes clear as soon as one tries to obtain a more exact understanding of the accelerated pace of social change characteristic of our time. It would be regrettable if extra-scientific methods were permanently to conceal elements of the problem capable of immediate investigation. It is clear from the foregoing survey of the problem as it stands today that a commonly accepted approach to it does not exist. The social sciences in various countries only sporadically take account of the achievements of their neighbors. In particular, German research into the problem of generations has ignored results obtained abroad. Moreover, the problem has been tackled by specialists in many different sciences in succession; thus, we possess a number of interesting sidelights on the problem as well as contributions to an overall solution, but no consciously directed research on the basis of a clear formulation of the problem as a whole. The multiplicity of points of view, resulting both from the peculiarities of the intellectual traditions of various nations and from those of the individual sciences, is both attractive and fruitful; and there can be no doubt that such a wide problem can only be solved as a result of cooperation between the most diverse disciplines and nationalities. However, the cooperation must somehow be planned and directed from an organic center. The present status of the problem of generations thus affords a striking illustration of the anarchy in the social and cultural sciences, where everyone starts out afresh from his own point of view (to a certain extent, of course, this is both necessary and fruitful), never pausing to consider the various aspects as part of a single general problem, so that the contributions of the various disciplines to the collective solution could be planned.
Libra: Divide and Conquer to Verify Forwarding Tables in Huge Networks

Data center networks often have errors in the forwarding tables, causing packets to loop indefinitely, fall into black-holes or simply get dropped before they reach the correct destination. Finding forwarding errors is possible using static analysis, but none of the existing tools scale to a large data center network with thousands of switches and millions of forwarding entries. Worse still, in a large data center network the forwarding state is constantly in flux, which makes it hard to take an accurate snapshot of the state for static analysis. We solve these problems with Libra, a new tool for verifying forwarding tables in very large networks. Libra runs fast because it can exploit the scaling properties of MapReduce. We show how Libra can take an accurate snapshot of the forwarding state 99.9% of the time, and knows when the snapshot cannot be trusted. We show results for Libra analyzing a 10,000 switch network in less than a minute, using 50 servers.