Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing a questionnaire to measure perceived attributes of eHealth innovations.

OBJECTIVE To design a valid and reliable questionnaire to assess perceived attributes of technology-based health education innovations. METHODS College students in 12 personal health courses reviewed a prototype eHealth intervention using a 30-item instrument based upon diffusion theory's perceived attributes of an innovation. RESULTS Principal components analysis found 5 factors accounted for 44.4% of the variance: 29.0% (relative advantage), 9.6% (simplicity), 6.5% (trialability), 5.0% (observability), and 4.4% (translatability). Internal consistency reliability ranged from . 66 to . 91 for the 5 factors. CONCLUSION The instrument can help eHealth developers determine and improve the adoption potential of their applications throughout the development cycle.
Ancestor Advantages Prime Better Intellectual Performances Evolutionary Psychology-Based Intelligence Priming Effect

Research has verified that human beings’ intellectual performances can be influenced by intelligence priming. Evolutionary psychology holds that the evolutionary psychological mechanisms which imitate the others, such as intelligence priming, is of survival values. By priming, human beings can not only predict others’ complex behaviors, but also accelerate and improve the behaviors that they imitated, that is, to acquire better intellectual performance by use of intelligence priming. This research explores intelligence priming effect from the perspective of evolutionary psychology with both the two experiments employing general intelligence tasks as the inspection method of intelligence priming effect so as to investigate the impacts of ancestors as priming material for the ingroup/outgroup differentiation on the intelligence priming effect. The results indicate that: (1) ancient wise men priming effects are saliently higher than modern wise men priming effects; (2) ancestor priming and modern men priming belong to different psychological mechanisms; and (3) assimilation effect and contrast effect appear in intelligence priming effects. In conclusion, ingroup ancestor priming, i.e., ancestor advantages, indeed can motivate people’s better intellectual performances.
Interpersonal Trust in Organisations: An Empirical Investigation of Workplace Outcomes in Two Countries

This research hypothesised that particular workplace behavioural outcomes can be explained by interpersonal trust, considering the traditional perspectives on trust as a social glue lowering transaction costs. We employed an approach of distinguishing three trust objects, namely, trust in peers, trust in the supervisor, and trust in top management. Survey data on interpersonal trust, affective commitment (AC), intention to turnover (ITT), job satisfaction (JS) and job performance (JP) was collected from professionals working in Turkey (N = 134) and the USA (N = 150). Data were analysed using partial least square based structural equation modelling. Findings in general suggested a normative point of view of trust, and discussions from comparative cultural contexts were given. Evidence shows that AC was positively associated with trust in peers and trust in top management in both countries. JS was explained by trust in supervisors in the US sample, whereas trust in top management predicted JS in the Turkey sample. ITT, due to its economic-grained nature, did not associate with any of the trust variables, implying the distinction between social exchange and economic exchange. JP and trust were inversely associated in the samples from both countries, revealing a team effect and contradicting the initial hypothesis. Practical implications were discussed.
Identifying Gender from Unaligned Facial Images by Set Classification

Rough face alignments lead to suboptimal performance of face identification systems. In this study, we present a novel approach for identifying genders from facial images without proper face alignments. Instead of using only one input for test, we generate an image set by randomly cropping out a set of image patches from a neighborhood of the face detection region. Each image set is represented as a subspace and compared with other image sets by measuring the canonical correlation between two associated subspaces. By finding an optimal discriminative transformation for all training subspaces, the proposed approach with unaligned facial images is shown to outperform the state-of-the-art methods with face alignment.
Livelihoods and land management in the Ioba Province in south-western Burkina Faso

4 1 INTRODUCTION 5 1.1 The gestion des terroirs villageois approach 5 1.2 Cotton cultivation 6 2 CONCEPTUAL FRAMEWORK 8 3 THE STUDY SITE 9 3.1 Social and economic characteristics 10 3.2 Biophysical conditions of the study region 12 4 METHODS AND DATA COLLECTION 15 4.1 Identification of Livelihood Determinants 15 4.2 Data source 16 5 RESULTS AND DISCUSSION 21 5.1 Determinants of livelihood in the study site 21 5.2 Livelihoods of identified groups 22 5.3 Income equality 29 5.4 Land management of the household types 29
Analysis of the Incidence of Pelvic Trauma in Fatal Automobile Accidents

Pelvic fractures are frequent complications of motor vehicle accidents, and motor vehicle accidents are the most common cause of pelvic fracture. Although pelvic fractures are associated with considerable morbidity and mortality, there has traditionally been no attempt to grade or classify pelvic fractures during postmortem examination. The authors performed a retrospective study of cases examined at the Jefferson County Coroner/Medical Examiner Office from 1994 to 1996, reviewing investigative reports and autopsy findings. Radiographs were examined for the presence and Tile type of pelvic fracture. Pelvic fractures were identified in 88 of 392 cases (23%). In most (89%), the pelvic fracture was readily classified according to Tile type on the basis of radiographs and the inferred mechanism of injury. This study indicates that current estimates of the mortality of pelvic fractures are low because of the exclusion of individuals who do not survive to hospitalization. Furthermore, pelvic fractures in rapidly fatal motor vehicle accidents tend to be more severe than fractures in individuals who have a significant interval of survival. The presence and classification of pelvic fractures may be readily determined by radiographs in most cases. The Tile classification scheme is easy to apply and has important implications in the comparison of study groups.
DeepGaze II: Reading fixations from deep features trained on object recognition

Here we present DeepGaze II, a model that predicts where people look in images. The model uses the features from the VGG-19 deep neural network trained to identify objects in images. Contrary to other saliency models that use deep features, here we use the VGG features for saliency prediction with no additional fine-tuning (rather, a few readout layers are trained on top of the VGG features to predict saliency). The model is therefore a strong test of transfer learning. After conservative cross-validation, DeepGaze II explains about 87% of the explainable information gain in the patterns of fixations and achieves top performance in area under the curve metrics on the MIT300 hold-out benchmark. These results corroborate the finding from DeepGaze I (which explained 56% of the explainable information gain), that deep features trained on object recognition provide a versatile feature space for performing related visual tasks. We explore the factors that contribute to this success and present several informative image examples. A web service is available to compute model predictions at this http URL.
Georisk: Assessment and Management of Risk for Engineered Systems and Geohazards

3-(3-Indolyl)quinuclidines for the formula I Ind-RI in which Ind is a 3-indolyl group which is unsubstituted or monosubstituted to tetrasubstituted by C1-4-alkyl, trifluoromethyl, C1-4-alkoxy, C1-4-alkylthio, fluorine, chlorine, hydroxyl, hydroxymethyl, C6-10-aryloxy, C7-11-aralkyloxy, C1-5-acyloxy, C6-10-aroyloxy, C1-4-alkylsulfonyloxy, C6-10-arylsulfonyloxy, carboxyl, C1-4-alkoxycarbonyl and/or methylenedioxy and R is 3-quinuclidinyl or 2,3-dehydro-3-quinuclidinyl, and their physiologically acceptable salts can be used as psychopharmaceuticals.
Nuclear Norm Regularized Least Squares Optimization on Grassmannian Manifolds

This paper aims to address a class of nuclear norm regularized least square (NNLS) problems. By exploiting the underlying low-rank matrix manifold structure, the problem with nuclear norm regularization is cast to a Riemannian optimization problem over matrix manifolds. Compared with existing NNLS algorithms involving singular value decomposition (SVD) of large-scale matrices, our method achieves significant reduction in computational complexity. Moreover, the uniqueness of matrix factorization can be guaranteed by our Grassmannian manifold method. In our solution, we first introduce the bilateral factorization into the original NNLS problem and convert it into a Grassmannian optimization problem by using a linearized technique. Then the conjugate gradient procedure on the Grassmannian manifold is developed for our method with a guarantee of local convergence. Finally, our method can be extended to address the graph regularized problem. Experimental results verified both the efficiency and effectiveness of our method.
A 24-week open-label Phase I/II evaluation of the HIV protease inhibitor MK-639 (indinavir)

Objective:To investigate the safety, pharmacokinetics, and activity of the orally bioavailable protease inhibitor MK-639. Design:An open-label Phase I/II trial of medically stable subjects with screening CD4 lymphocyte counts ≤ 300×106/l and ≥ 20 000 HIV RNA copies/ml. Pharmacokinetics were performed at days 1 and 15. In order to better understand the relationships between drug exposure, baseline activity markers, and their changes during the study, mathematical modeling was performed using the traditional sigmoid-Emax relationship of pharmacologic effect and first order inhomogeneous differential equations for a two compartment system. Results:The five men enrolled had extensive prior nucleoside therapy (mean, 32.6 ± 25.6 months), a low mean CD4 lymphocyte cell count (CD4 count, 66.1 ± 61×106/l and CD4 percentage, 4.4 ± 3.1%), high soluble tumor necrosis factor-α type II (sTNFII) receptor concentration (6.23 ± 2.76 ng/ml) and high viral load (5.13 ± 0.46 log10 RNA copies/ml; geometric mean, 133 941 copies/ml). The drug was well tolerated at a dose of 600 mg every 6 h. The steady state concentrations Cmax and Cmin were 4.94 ± 2.16 μM and 0.28 ± 0.1 μM, respectively, which are ≈50 and 3 times the 95% inhibitory concentration (IC95) for clinical isolates, respectively. The mean increase in CD4 cell count was 143×106/l (217% increase), the mean increase in CD4 percentage was 5.2 percentage points (118%), mean decrease in HIV RNA was 1.55 log10 RNA copies/ml (a geometric mean difference of 130 120 copies/ml or 97% decrease) with a slow upward drift on continued therapy to a mean 0.64 log10 RNA copies/ml decrease by week 24 (a geometric mean difference of 103 084 copies/ml or 77% decrease), and a mean decrease in sTNFII receptors of 2.78 ng/ml (45% decrease). The mean CD4 counts per week as a function of the starting CD4 counts fit a sigmoid-Emax relationship (r2 = 0.998, P < 0.0001) with the return of CD4 cells being strongly related to the number of CD4 cells at baseline. Drug exposure as measured by either the total exposure (area under the concentration/time curve) or as the Cmin gave similar significant relationships to the fractional inhibition of HIV generation (r2 = 0.999, P < 0.0001, and r2 = 0.996, P < 0.0001, respectively). Conclusions:MK-639 appears to have significant dose-related antiviral activity and is well tolerated.
Quantitative nanoscale imaging of orientational order in biological filaments by polarized superresolution microscopy

Significance Central biological processes in cells and tissues are intrinsically governed by the structural order of biomolecular assemblies. It is thus a key factor to decipher how these assemblies organize in complex molecular organizations, from the nanometric to the macroscopic scale. Polarized microscopy can access such information; however, signals are spatially averaged over the optical diffraction limit and are contaminated by the fluorophores’ orientational flexibility of their linker to the biomolecules. By bringing polarized fluorescence down to superresolution microscopy using single-molecule localization, we show that structural imaging can be scaled down to nanometric scales and is able to discriminate fluorophores’ flexibility from biomolecules’ orientational order. We demonstrate nanoscale structural imaging in fundamental biological filament organizations. Essential cellular functions as diverse as genome maintenance and tissue morphogenesis rely on the dynamic organization of filamentous assemblies. For example, the precise structural organization of DNA filaments has profound consequences on all DNA-mediated processes including gene expression, whereas control over the precise spatial arrangement of cytoskeletal protein filaments is key for mechanical force generation driving animal tissue morphogenesis. Polarized fluorescence is currently used to extract structural organization of fluorescently labeled biological filaments by determining the orientation of fluorescent labels, however with a strong drawback: polarized fluorescence imaging is indeed spatially limited by optical diffraction, and is thus unable to discriminate between the intrinsic orientational mobility of the fluorophore labels and the real structural disorder of the labeled biomolecules. Here, we demonstrate that quantitative single-molecule polarized detection in biological filament assemblies allows not only to correct for the rotational flexibility of the label but also to image orientational order of filaments at the nanoscale using superresolution capabilities. The method is based on polarized direct stochastic optical reconstruction microscopy, using dedicated optical scheme and image analysis to determine both molecular localization and orientation with high precision. We apply this method to double-stranded DNA in vitro and microtubules and actin stress fibers in whole cells.
Joining Forces – Combining Cognition-Targeted Motor Control Training with Group or Individual Pain Physiology Education: A Successful Treatment For Chronic Low Back Pain

Abstract Chronic unremittent low back pain (LBP) is characterised by cognitive barriers to treatment. Combining a motor control training approach with individualised education about pain physiology is effective in this group of patients. This randomized comparative trial (i) evaluates an approach to motor control acquisition and training that considers the complexities of the relationship between pain and motor output, and (ii) compares the efficacy and cost of individualized and group pain physiology education. After an "ongoing usual treatment" period, patients participated in a 4-week motor control and pain physiology education program. Patients received four one-hour individualized education sessions (IE) or one 4-hour group lecture (GE). Both groups reduced pain (numerical rating scale) and disability (Roland Morris Disability Questionnaire). IE showed bigger decreases, which were maintained at 12 months (P <0.05 for all). The combined motor control and education approach is effective. Although group education imparts a lesser effect, it may be more cost-efficient.
Physical Education and Sport for the Deaf: Rethinking the Least Restrictive Environment

Efforts to include children with disabilities in mainstream settings often raise questions as to what constitutes “least restrictive. ” This paper addresses educational placement of deaf children, especially as it pertains to physical education and sport. Many leaders in deaf education hold that placement of deaf children in public schools often occurs without regard to their socioemotional/cultural/language needs. This paper provides a rationale for the residential school as a viable and legitimate placement option for deaf children. Also included in the paper is a brief historical overview of deaf education including the contributions of residential schools to deaf sport and deaf culture.
Journal of Cardiovascular Magnetic Resonance Comparison of 2d and 3d Calculation of Left Ventricular Torsion as Circumferential-longitudinal Shear Angle Using Cardiovascular Magnetic Resonance Tagging

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Purpose: To compare left ventricular (LV) torsion represented as the circumferential-longitudinal (CL) shear angle between 2D and 3D quantification, using cardiovascular magnetic resonance (CMR). Methods: CMR tagging was performed in six healthy volunteers. From this, LV torsion was calculated using a 2D and a 3D method. The cross-correlation between both methods was evaluated and comparisons were made using Bland-Altman analysis. Results: The cross-correlation between the curves was r 2 = 0.97 ± 0.02. No significant time-delay was observed between the curves. Bland-Altman analysis revealed a significant positive linear relationship between the difference and the average value of both analysis methods, with the 2D results showing larger values than the 3D. The difference between both methods can be explained by the definition of the 2D method. Conclusion: LV torsion represented as CL shear quantified by the 2D and 3D analysis methods are strongly related. Therefore, it is suggested to use the faster 2D method for torsion calculation.
Twelve-step program attendance and polysubstance use: interplay of alcohol and illicit drug use.

OBJECTIVE The primary aim of this study was to advance understanding of the efficacy of 12-step programs by determining the temporal relationships between alcohol and illicit drug use among 12- step program affiliates. METHOD A total of 253 early 12-step affiliates without extensive histories of Alcoholics Anonymous (AA) attendance were recruited from substance use treatment and community-based AA. A majority of the sample met criteria for a diagnosis of alcohol dependence, reported lifetime use of illicit drugs, and reported illicit drug use in the 90-day period before recruitment. After informed consent, participants were interviewed at intake and in 3-month increments for 1 year. RESULTS Preliminary analyses indicated that 12-step attendance was predictive of reductions in substance use and that such reductions were not moderated by illicit substance use disorder diagnosis or alcohol problem severity. Lagged hierarchical linear models indicated that illicit drug use was a robust predictor of later use of alcohol, although the frequency and intensity of drinking were contingent on whether participants sustained 12-step program affiliation. Alcohol use did not predict later illicit drug use among participants who sustained 12-step program participation. CONCLUSIONS Findings suggest that 12-step participation may serve as a protective factor after substance use occurs. Although our results suggest that the initiation of illicit drug use may undermine efforts to achieve and sustain abstinence from alcohol, our findings do not suggest that alcohol use necessarily mobilizes relapse across different substances among 12-step program affiliates.
Does Monitoring Bispectral Index or Spectral Entropy Reduce Sevoflurane Use?

A decrease in volatile anesthetic consumption has been demonstrated using bispectral index (BIS), whereas data concerning spectral entropy are lacking. One hundred and forty adult patients scheduled for surgical procedures lasting more than 1 h were prospectively randomized to receive an anesthetic controlled either by BIS or by spectral entropy or solely by clinical variables. Anesthesia was induced with propofol and sufentanil. Sufentanil was infused continuously thereafter. Sevoflurane was administered in 1 L/min O2/N2O. The sevoflurane concentration was adjusted according to conventional clinical variables in the standard practice group, whereas the 40–60 interval was applied for the BIS and spectral entropy-guided groups. The sevoflurane vaporizer was weighed before and after anesthesia, and consumption was calculated. Groups were comparable for demographic data except for weight (heavier in the spectral entropy-guided group, P < 0.05). Compared with standard practice, patients with BIS or spectral entropy monitoring required 29% less sevoflurane (normalized sevoflurane consumption to the weights of the patients and to the durations of anesthesia; both P < 0.03) and a similar sufentanil dose. An unintended improvement in the standard practice group (positive bias) was observed. In conclusion, BIS and spectral entropy monitoring have the same sparing effect of sevoflurane.
Atrophy of the Hippocampal Formation in Early Familial Alzheimer's Disease

The hippocampal formation (HF) is known from pathological and magnetic resonance imaging (MRI) studies to become severely atrophied in established Alzheimer's disease (AD). This study examined whether changes in the HF could also be detected in very early AD by scanning subjects at risk of developing familial AD (FAD). Five at risk members of a pedigree with the amyloid precursor protein (APP) 717 valine to glycine mutation underwent serial MRI scanning with volumetric measurement of the HF as well as neurological and neuropsychological assessments. Over a period of two years two subjects became clinically affected, a loss of up to 20% of the volume of the HF occurred in the two years over which symptoms first appeared. Asymmetrical HF atrophy was shown to have been present before the development of overt symptoms. This may have important implications for early diagnosis in AD more generally.
Correction: The Release Rate of Environmental DNA from Juvenile and Adult Fish

There is an error in the third equation. Please view the complete, correct equation here: t half ¼ log e 2 b In the penultimate sentence of the Abstract, the last sentence of the first paragraph in the Results section, and the first sentence of the final paragraph of the Discussion section the half-life value is incorrectly calculated as 6.3. The correct half-life value should read 6.7. open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.