Miracle-dz/UniFAR-FTUs huggingface dataset:
Getting the Right Idea: Semantic Activation in the Right Hemisphere May Help Solve Insight Problems

Two experiments examined hemispheric differences in information processing that may contribute to solving insight problems. We propose that right-hemisphere (RH) coarse semantic coding is more likely than left-hemisphere (LH) fine semantic coding to activate distantly related information or unusual interpretations of words, and thus more likely to activate solution-relevant information for insight problems. In Experiment 1, after trying to solve insight problems, participants read aloud solution or unrelated target words presented to the left visual field (lvf) or right visual field (rvf). Participants showed greater lvf-RH than rvf-LH priming for solutions for solved problems and priming only in the lvf-RH for unsolved problems. In Experiment 2, participants showed an lvf-RH advantage for recognizing solutions to unsolved problems. These results demonstrate that in a problem-solving context, there was greater activation of solution-relevant information in the RH than in the LH. This activation is useful for recognizing, and perhaps producing, solutions to insight problems.
New product development processes and new product profitability: Exploring the mediating role of speed to market and product quality

In new product development, faster is not always better. Conceptually, being faster to market should improve financial performance by improving product quality and reducing development expenses. Empirical support is mixed, however, demonstrating that higher speed to market exhibits an inverted U-shaped relationship with product profitability. Conventional wisdom and empirical research suggest managers make speed to market‐product quality‐development expense trade-offs. A particular concern regarding speed to market is that extreme speed may jeopardize product quality. Some researchers suggest that speed to market improves product quality while others suggest firms must balance both speed to market and product quality. Also, shorter lead times may be associated with reduced development expenses, but empirical evidence is conflicting. This research attempts to reconcile conflicting results regarding the speed to market‐product quality relationship, their joint impact on product profitability, and their mediation role in the effects of development expenses and cross-functional integration on product profitability. Partial least squares (PLS) is used to analyze multiplexed archival and survey data collected from NPD managers for 1115 different NPD projects in several firms. The results support the hypothesized equations, explaining 27% of speed to market variance, 35% of product quality variance, and 45% of product profitability variance. This study makes two contributions. First, because speed to market and product quality are related, simultaneous consideration of both factors enhances insight into their joint effect. Second, it provides evidence that speed to market and product quality jointly mediate development expense by NPD phase and cross-functional integration effects on product profitability. Key results from the large sample data analysis include the following. Speed to market and product quality both enhance product profitability, but the impact of speed to market is larger than that of product quality. Speed to market and product quality partially mediate the impact of fuzzy front end phase expenses on product profitability, while expenses in the latter phases exhibit no impact on the mediators or profitability. Thus, the results suggest that trade-offs are made not only between time, quality, and expense (i.e., if additional expenses are incurred at all), but also that trade-offs relate to when (i.e., in which NPD phase) additional development expenses are incurred. Finally, crossfunctional integration (both internal and external) substantially impacts product profitability through a mix of direct and mediated effects.
The Relationships Among Perceived Discrimination, Marianismo Gender Role Attitudes, Racial-Ethnic Socialization, Coping Styles, and Mental Health Outcomes in Latina College Students

The current study examined the links between perceived discrimination, marianismo gender role beliefs, racial-ethnic socialization (preparation for bias), coping strategies (engagement vs. disengagement), and mental health outcomes among 211 Latina college students. First, the authors investigated predictions about mediation effects of ethnic socialization and marianismo in the association between perceived discrimination and coping strategies. Second, they tested predictions about mediation effects of coping strategies in the link between perceived discrimination and mental health outcomes. Results of path analyses showed that perceived discrimination was positively related to familismo and spiritual marianismo pillars, preparation for bias, and engagement coping strategies. Furthermore, the link between perceived discrimination and engagement coping strategies was partially mediated via preparation for bias. Finally, perceived discrimination, disengagement coping strategies and self-silencing marianismo attitudes were negatively linked to mental health. Overall, these findings highlight the complex ways in which coping strategies are linked with one’s ethnic and gender socialization and related to perceived discrimination and mental health outcomes. El presente estudio examinó las relaciones entre la discriminación percibida, la socialización étnica-racial (preparación de discriminación), roles de marianismo creencias, estrategias (de compromiso frente a la desconexión) y los resultados de salud mental entre los 211 estudiantes universitarias Latinas. Primero, se investigó predicciones sobre los efectos de mediación de socialización étnica y el marianismo en la asociación entre las estrategias de afrontamiento y la discriminación percibida. También, investigamos las predicciones acerca de los efectos de mediación de las estrategias de supervivencia en la relación entre la discriminación percibida y el salud mental. Los resultados de los análisis mostraron que discriminación percibida fue relacionado positivamente con la preparación para la discriminación, el familismo y pilares Marianismo espirituales, así como las estrategias de participación de afrontamiento. Además, la relación entre las estrategias de afrontamiento de compromiso y la discriminación percibida fue parcialmente mediada a través de la preparación de discriminación. Finalmente, la discriminación percibida, las estrategias de afrontamiento y “self-silencing” Marianismo actitudes estaban relacionado negativamente a la salud mental. En general, estos resultados ponen de relieve las complejas formas en que las estrategias de afrontamiento están vinculados con la propia socialización étnica y de género y relacionadas con la discriminación percibida y los resultados de salud mental.
Clinical Practice and Epidemiology in Mental Health

The formation of social bonding is fundamental for several animals, including humans, for its relevant and obvious impact upon reproduction and, thus, survival of the species. Recent data would suggest that oxytocin might be one of the mediators of this process. Given the paucity of data on the possible involvement of oxytocin in human attachment, the present study was aimed to explore the possible relationships between the plasma levels of this neuropeptide and romantic attachment in healthy subjects. Forty-five healthy subjects who volunteered for the study, were included in the study. The romantic attachment was assessed using the Italian version of the socalled "Experiences in Close Relationships" (ECR), a self-report questionnaire for measuring this parameter in adults. The results showed that attachment anxiety and oxytocin are positively linked in romantic attachment to a statistically significant degree (r = 0.30, p = 0.04), that is, the higher the oxytocin levels the higher the score on the anxiety scale of the ECR. The authors suggest the hypothesis that this link represents one of the biological processes resulting in those rewarding emotions related to romantic attachment.
RadioVisor: a slicing plane for radio access networks

To cope with the exponential traffic growth, increasingly diverse traffic mix including voice, video, machine-tomachine(M2M), and the spectrum shortage, wireless networks have to get densely deployed and dynamically adapt to meet the distinct requirements of diverse traffic classes. However, current network architectures are ill-equipped to support a dense and dynamic wireless infrastructure. First, since it will be impossible to obtain regularly placed cell sites for an infrastructure with higher density, basestations will be deployed wherever possible in a chaotic fashion. However, a chaotic and dense wireless deployment will be very complex to manage, since it will experience highly variable loads and unpredictable inter-cell interference among other things. Further since spectrum is limited, very likely all the basestations will be operating on the same frequency (referred to as frequency reuse factor of one). This leads to a tremendous amount of inter-cell interference, and that becomes the limiting factor for network capacity. Second, a dense infrastructure is very expensive to deploy and operate. Current deployments are unaffordable except to the largest operators, so a deployment with significantly higher density will likely be enormously expensive even for the largest operators, preventing smaller operators from expanding and offering consumers the choices they need. Rather than looking at the radio access layer as a collection of independent base stations, SoftRAN [1] proposes that all base stations deployed in a geographical area should be abstracted as a virtual big-base station which is made up of radio elements (the individual physical base stations). A logically centralized control plane makes all decisions regarding handovers and interference management, while the radio elements are simpler devices with minimal control logic. Since all neighboring base stations are allocating from a fixed set of shared resources, SoftRAN abstracts the radio resources as a 3D resource grid of space, time, and frequency slots; and program them in a software defined fashion through a logically centralized radio access control plane. Rather than having a single entity controlling radio access networks which limits sharing as standardized by 3GPP on LTE [2], we build on SoftRAN and argue that the 3D resource grid should be dynamically sliced based on traffic among virtual operators. This will enable virtual operators to innovate in scheduling, interference management and even in physical layer (PHY). Operators should be able to flexibly define slices based on subscriber attributes and application types (e.g. voice, video) to support a wide range of application requirements. Such architecture raises unique challenges compared to data-center and enterprise networks. Indeed, radio resources are inherently coupled due to the shared nature of wireless media. Unlike FlowVisor [3] which slices the flow space and easily isolates the disjoint subspaces. Slicing radio resources would need to consider interference.
The behavior of multivariate maxima of moving maxima processes

In the characterization of multivariate extremal indices of multivariate stationary processes, multivariate maxima of moving maxima processes, or M4 processes for short, have been introduced by Smith and Weissman. Central to the introduction of M4 processes is that the extreme observations of multivariate stationary processes may be characterized in terms of a limiting max-stable process under quite general conditions, and that a max-stable process can be arbitrarily closely approximated by an M4 process. In this paper, we derive some additional basic probabilistic properties for a finite class of M4 processes, each of which contains finite-range clustered moving patterns, called signature patterns, when extreme events occur. We use these properties to construct statistical estimation schemes for model parameters.
Consonant and sign phoneme acquisition in signing children following cochlear implantation

Abstract Deaf children from signing programs provide new opportunities to investigate changes in sign and speech acquisition following cochlear implantation. We describe the acquisition of sign phonemes (location, movement, and handshapes) and speech phonemes (consonants) in 22 implanted children with diverse demographic backgrounds. New consonants and new sign phonemes emerged in developmentally expected sequences and with statistically significant correlation coefficients between cumulative number of new consonants and new sign phonemes over time. Regression slopes from plotted z scores revealed a burst in consonant and sign growth in early months post-implant, with continuous but plateauing growth over time. These results and documentation of developmental levels of sign and speech phoneme trajectories should be helpful to other researchers and to clinicians working with signing children who have cochlear implants.
Temporal and spatial integration in the rat SI vibrissa cortex.

Glass micropipettes were used to record the activity of 124 single units in the somatosensory vibrissa cortex (SI) of 16 rats in response to combined deflections of contralateral vibrissae. Compact multiangular electromechanical stimulators were used to stimulate individual vibrissal hairs alone or in combinations of two or three adjacent whiskers. Each whisker was stimulated independently to produce controlled temporal and spatial patterns of mechanical stimuli. Following displacement of a vibrissa, unit discharges to subsequent deflections of adjacent whiskers are reduced in a time-dependent fashion. Response suppression is strongest at short interdeflection intervals, i.e., 10-20 ms and decreases progressively during the 50-100 ms following the first deflection. In many cases this period also corresponds with a reduction in ongoing unit discharges. Response suppression was not observed for first-order neurons recorded in the trigeminal ganglion of barbiturate-anesthetized rats. In the cortex, the presence and/or degree of response suppression depends on a number of spatial factors. These include 1) the angular direction(s) in which the individual hairs are moved, 2) the sequence in which two whiskers are deflected, that is, which one is deflected first, 3) the particular combination of whiskers stimulated, and 4) the number (2 or 3) of vibrissae comprising the multiwhisker stimulus. Within a vertical electrode penetration, one particular whisker typically elicits the strongest excitatory and inhibitory effects; other, nearby vibrissae elicit variable (or no) excitation or inhibition. Excitatory and inhibitory subregions of a receptive field could thus be distributed asymmetrically around the maximally effective whisker. In these cases, the receptive fields displayed spatial orientations. Quantitative criteria were used to classify 30 cortical units on the basis of the distribution of inhibitory subregions on either side of the maximally effective whisker. Twenty-one of these cells had receptive fields (RFs) with symmetrical inhibitory side regions. Responses of the other nine units were strongly suppressed by a preceding deflection of a vibrissa on one side but relatively unaffected, or even slightly facilitated, by preceding deflection of the whisker on the other side. (ABSTRACT TRUNCATED AT 400 WORDS)
metricDTW: local distance metric learning in Dynamic Time Warping

We propose to learn multiple local Mahalanobis distance metrics to perform k-nearest neighbor (kNN) classification of temporal sequences. Temporal sequences are first aligned by dynamic time warping (DTW); given the alignment path, similarity between two sequences is measured by the DTW distance, which is computed as the accumulated distance between matched temporal point pairs along the alignment path. Traditionally, Euclidean metric is used for distance computation between matched pairs, which ignores the data regularities and might not be optimal for applications at hand. Here we propose to learn multiple Mahalanobis metrics, such that DTW distance becomes the sum of Mahalanobis distances. We adapt the large margin nearest neighbor (LMNN) framework to our case, and formulate multiple metric learning as a linear programming problem. Extensive sequence classification results show that our proposed multiple metrics learning approach is effective, insensitive to the preceding alignment qualities, and reaches the state-of-the-art performances on UCR time series datasets.
The Predictive Role of Red Cell Distribution Width in Mortality among Chronic Kidney Disease Patients

Background Recently, accumulating evidence has demonstrated that RDW independently predicts clinically important outcomes in many populations. However, the role of RDW has not been elucidated in chronic kidney disease (CKD) patients. We conducted the present study with the aim to evaluate the predictive value of RDW in CKD patients. Methods A retrospective observational cohort study of 1075 stage 3–5 CKD patients was conducted in a medical center. The patients’ baseline information included demographic data, laboratory values, medications, and comorbid conditions. The upper limit of normal RDW value (14.9%) was used to divide the whole population. Multivariate Cox regression analysis was used to determine the independent predictors of mortality. Results Of the 1075 participants, 158 patients (14.7%) died over a mean follow-up of approximately 2.35 years. The crude mortality rate was significantly higher in the high RDW group (high RDW group, 22.4%; low RDW group 11%, p <0.001). From the adjusted model, the high RDW group was correlated with a hazard ratio of 2.19 for overall mortality as compared with the low RDW group (95% CI = 1.53–3.09, p<0.001). In addition, the high RDW group was also associated with an increased risk for cardiovascular disease (HR = 2.28, 95% CI = 1.14–4.25, p = 0.019) and infection (HR = 1.9, 95% CI = 1.15–3.14, p = 0.012)) related mortality in comparison with the low RDW group. Conclusions In stage 3–5 CKD patients, RDW was associated with patient mortality of all-cause, cardiovascular disease and infection. RDW should be considered as a clinical predictor for mortality when providing healthcare to CKD patients.
Does remifentanil attenuate renal ischemia–reperfusion injury better than dexmedetomidine in rat kidney?

Background Ischemia–reperfusion (I/R) injury is a common cause of patient morbidity and mortality in the perioperative period. Patients undergoing long-lasting, abdominal, and urogenital surgeries with risk factors such as advanced age, peripheral artery disease, diabetes mellitus, renovascular disease, and congestive heart failure are candidates for acute kidney injury (AKI) due to impaired renal perfusion and decreased functional renal reserve. Pharmacological agents with multiple functions and anti-oxidative and anti-inflammation properties may be promising preventative strategies for AKI. Recently, dexmedetomidine (dex) has been postulated to have renoprotective effects. Objectives We aimed to investigate the protective effects of an intravenous anesthetic remifentanil in renal I/R injury in the rat in comparison with dex. Materials and methods A total of 30 Sprague Dawley adult rats were randomly assigned into five groups: the control group (group C, n=6), the sham group (group Sh, n=6, saline-infused rats without I/R injury), the saline group (group S, n=6, saline-infused rats with I/R injury), the remifentanil-treated group (group REM, n=6), and the dexmedetomidine-treated group (group DEX, n=6). The infusions (saline, remifentanil, and dex) were started after anesthesia induction and right nephrectomy and continued until the end of the surgical procedure. In I/R injury groups, the left renal artery and vein were occluded together by a clamp for 30 minutes and reperfusion lasted for 30 minutes. The rats were sacrificed after reperfusion, and the left kidney tissue was harvested. Blood samples were drawn from all animals to evaluate plasma neutrophil gelatinase-associated lipocalin (NGAL) at the beginning, 15 minutes after ischemia, 15 minutes after reperfusion, and 6 hours after the surgical procedure (T0, T1, T2, and T3, respectively). Results The plasma NGAL levels exhibited increase at T1, T2, and T3 compared to the levels at T0 in group S (P<0.05). In group REM, there was a significant increase in plasma NGAL levels at T3 in comparison to those at T0, T1, and T2. The plasma NGAL levels at T2 in group S were significantly higher than those at T2 in group DEX (P<0.05). The groups S and REM showed significantly higher plasma NGAL levels at T3 compared to those at T0 (P<0.05). Upon histological examination, there was no difference among the study groups when left kidneys were evaluated (P>0.05). Conclusion The NGAL levels and histopathological findings reflected protection by dex against renal I/R injury. However, the same exact results could not be mentioned for remifentanil depending on our study results.
Large-Scale Simulation of Oceanic Gas Hydrate Dissociation in Response to Climate Change

Vast quantities of methane are trapped in oceanic hydrate deposits, and there is concern that a rise in the ocean temperature will induce dissociation of these hydrate accumulations, potentially releasing large amounts of carbon into the atmosphere. Because methane is a powerful greenhouse gas, such a release could have dramatic climatic consequences. The recent discovery of active methane gas venting along the landward limit of the gas hydrate stability zone (GHSZ) on the shallow continental slope west of Svalbard suggests that this process may already have begun, but the source of the methane has not been determined. This study performs a 2D simulation of hydrate dissociation in conditions representative of the Svalbard margin to assess whether such hydrates could be responsible for in the observed gas release. The results show that shallow, low-saturation hydrate deposits, if subjected to recent measured or predicted temperature changes at the seafloor, can release quantities of methane at the magnitudes recorded, and that the releases will be localized near the landward limit of the top of the GHSZ as observed. Both gradual and rapid warming is simulated, and localized gas release is observed for both cases. These suggest that hydrate dissociation and methane release as a result of climate change may be a real phenomenon, and that it already may be occurring.