Miracle-dz/UniFAR-FTUs huggingface dataset:
Gender Differences in Pay Equity: An Examination of the Working Adolescent

This study was conducted to determine whether adult gender-based wage inequities are mirrored in the adolescent population. A developmental perspective was taken while examining this topic, so as to pinpoint stages when divergences based on gender might occur. In order to ascertain this, 157 pre-and young adolescents ranging in age from 12-15 years old participated in our survey and a subset of this group (n=89) participated in the follow-up interview. Contained in both the survey and interview were questions pertaining to remuneration, employment, negotiation, gender stereotypes and attitudes about money. Results indicated that young females seem to receive a better financial start within the home than their male peers. However, females tend to take up stereotypic work which may limit their development of new professional skills. Additionally, females do employ negotiation strategies, but they seem to only employ them with parents and not with employers. Instead they seem to expect their employer to set their wages, without thought to, or desire for, the possibility that they could impact their employer’s decision. Furthermore, development of these skills or beliefs does not appear to be linear. Instead particular ages bring forth their own unique differences, and such milestones as the transition from elementary to high school bring about various changes to girls’ and boys’ experiences with work and wages. Overall, the issue of gender-based wage inequality is far more complex than was originally hypothesized and would benefit greatly from longitudinal study in the future. AN EXAMINATION OF THE WORKING ADOLESCENT 3
Entropy Numbers in Weighted Function Spaces and Eigenvalue Distributions of Some Degenerate Pseudodifferential Operators II

This paper is the continuation of [17]. We investigate mapping and spectral properties of pseudodifferential operators of type Ψ with χ χ ϵ ℝ and 0 ≤ γ ≤ 1 in the weighted function spaces B (ℝn, w(x)) and F (ℝn, w(x)) treated in [17]. Furthermore, we study the distribution of eigenvalues and the behaviour of corresponding root spaces for degenerate pseudodifferential operators preferably of type b2(x) b(x, D) b1(x), where b1(x) and b2(x) are appropriate functions and b(x, D) ϵ Ψ. Finally, on the basis of the Birman-Schwinger principle, we deal with the “negative spectrum” (bound states) of related symmetric operators in L2.
A new design for ultracompact multimode interference-based 2 x 2 couplers

We introduce here a new multimode interference-based 3-dB coupler that has a substantially smaller device geometry than conventional multimode interference structures. This new structure is based on a special multimode region shape and an appropriate launching technique which aids in circumventing the proximity limitations. Simulations show this structure can provide a decrease of a factor of three or more in the device size of the smallest 3-dB MMI coupler made to date.
Caregiver Satisfaction With Support Services

OBJECTIVES This article examines factors influencing satisfaction with support services of caregivers of frail older adults and determines what types of support services are associated with greater satisfaction, controlling for frail individual and caregiver characteristics. METHODS The study includes 291 frail older adults-caregiver dyads from Montreal in which caregivers receive support services. The Client Satisfaction Questionnaire-8 is used to measure caregiver satisfaction with these services. RESULTS Caregivers receiving information, advice, or emotional support, and those caring for seniors receiving integrated care are more likely to be highly satisfied. Other factors increasing satisfaction are fewer number of health problems of frail individuals, caregiver being the spouse of the frail person, as well as greater caregiver perceived health, autonomy in instrumental activities of daily living, and available social support. DISCUSSION The results support the importance of integrated care for frail seniors and informational services for their caregivers.
Attention and anticipation in fast visual-inertial navigation

Visual attention is the cognitive process that allows humans to parse a large amount of sensory data by selecting relevant information and filtering out irrelevant stimuli. This papers develops a computational approach for visual attention in robots. We consider a Visual-Inertial Navigation (VIN) problem in which a robot needs to estimate its state using an on-board camera and an inertial sensor. The robot can allocate limited resources to VIN, due to time and energy constraints. Therefore, we answer the following question: under limited resources, what are the most relevant visual cues to maximize the performance of visual-inertial navigation? Our approach has four key features. First, it is task-driven, in that the selection of the visual cues is guided by a metric quantifying the task performance. Second, it exploits the notion of anticipation, since it uses a simplified model for forward-simulation of robot dynamics, predicting the utility of a set of visual cues over a time horizon. Third, it is efficient and easy to implement, since it leads to a greedy algorithm for the selection of the most relevant visual cues. Fourth, it provides formal performance guarantees: we leverage submodularity to prove that the greedy selection cannot be far from the optimal (combinatorial) selection. Simulations and real experiments on agile micro aerial vehicles show that our approach leads to dramatic improvements in the VIN performance. In the easy scenarios, our approach outperforms the state of the art in terms of localization errors. In the most challenging scenarios, it enables accurate visual-inertial navigation while the state of the art fails to track robot's motion during aggressive maneuvers.
Tuning the mechanical properties of self-assembled mixed-peptide tubes

In this study, nano‐ and microscale fibrillar and tubular structures formed by mixing two aromatic peptides known to self‐assemble separately, (diphenylalanine and di‐D‐2‐napthylalanine) have been investigated. The morphology, mechanical strength and thermal stability of the tubular structures formed have been studied. The tubes are shown to consist of both peptides with some degree of nanoscale phase separation. The ability of the mixed peptides to form structures, which display variable mechanical properties dependent on the percentage composition of the peptides is presented. Such materials with tuneable properties will be required for a range of applications in nanotechnology and biotechnology.
Racial Disparity in Social Spatiality: Usage of National Parks and Opera Attendance

This study investigates the existence of an ethnic separation in different settings of leisure activities. I examine the relationship between race, gender, socioeconomic status, and education with respect to the usage of popular cultural activities and high cultural activities to demonstrate the racial disparity occurring in both. A literature review pertaining to the usage of outdoor recreation, as in camping and hiking evidences the influence of racism on the disparity in Nonwhite participation. In contrast to out-door leisure activities, literature evidences the influence of class instead of race for the disparity in indoor leisure activities. Using the 1993 General Social Survey (GSS), I am able to arrive at the conclusion that the type of leisure chosen by an ethnic group relates much less to the educational level, economic status or the place of residence as it does to the perception of the socially constructed settings. INDEX WORDS:
Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

Ductal carcinoma in situ (DCIS) is an often-diagnosed breast disease and a known, non-obligate, precursor to invasive breast carcinoma. In this review, we explore the clinical and pathological features of DCIS, fundamental elements of DCIS biology including gene expression and genetic events, the relationship of DCIS with recurrence and invasive breast cancer, and the interaction of DCIS with the microenvironment. We also survey how these various elements are being used to solve the clinical conundrum of how to optimally treat a disease that has potential to progress, and yet is also likely over-treated in a significant proportion of cases.
The Complete Mitochondrial Genome of Corizus tetraspilus (Hemiptera: Rhopalidae) and Phylogenetic Analysis of Pentatomomorpha

Insect mitochondrial genome (mitogenome) are the most extensively used genetic information for molecular evolution, phylogenetics and population genetics. Pentatomomorpha (>14,000 species) is the second largest infraorder of Heteroptera and of great economic importance. To better understand the diversity and phylogeny within Pentatomomorpha, we sequenced and annotated the complete mitogenome of Corizus tetraspilus (Hemiptera: Rhopalidae), an important pest of alfalfa in China. We analyzed the main features of the C. tetraspilus mitogenome, and provided a comparative analysis with four other Coreoidea species. Our results reveal that gene content, gene arrangement, nucleotide composition, codon usage, rRNA structures and sequences of mitochondrial transcription termination factor are conserved in Coreoidea. Comparative analysis shows that different protein-coding genes have been subject to different evolutionary rates correlated with the G+C content. All the transfer RNA genes found in Coreoidea have the typical clover leaf secondary structure, except for trnS1 (AGN) which lacks the dihydrouridine (DHU) arm and possesses a unusual anticodon stem (9 bp vs. the normal 5 bp). The control regions (CRs) among Coreoidea are highly variable in size, of which the CR of C. tetraspilus is the smallest (440 bp), making the C. tetraspilus mitogenome the smallest (14,989 bp) within all completely sequenced Coreoidea mitogenomes. No conserved motifs are found in the CRs of Coreoidea. In addition, the A+T content (60.68%) of the CR of C. tetraspilus is much lower than that of the entire mitogenome (74.88%), and is lowest among Coreoidea. Phylogenetic analyses based on mitogenomic data support the monophyly of each superfamily within Pentatomomorpha, and recognize a phylogenetic relationship of (Aradoidea + (Pentatomoidea + (Lygaeoidea + (Pyrrhocoroidea + Coreoidea)))).
An Update on Drugs Used for Lumbosacral Epidural Anesthesia and Analgesia in Dogs

This review aims to report an update on drugs administered into the epidural space for anesthesia and analgesia in dogs, describing their potential advantages and disadvantages in the clinical setting. Databases searched include Pubmed, Google scholar, and CAB abstracts. Benefits of administering local anesthetics, opioids, and alpha2 agonists into the epidural space include the use of lower doses of general anesthetics (anesthetic “sparing” effect), perioperative analgesia, and reduced side effects associated with systemic administration of drugs. However, the potential for cardiorespiratory compromise, neurotoxicity, and other adverse effects should be considered when using the epidural route of administration. When these variables are considered, the epidural technique is useful as a complementary method of anesthesia for preventive and postoperative analgesia and/or as part of a balanced anesthesia technique.
Organized Semantic Fluency and Executive Functioning in an Adult Clinical Sample and a Community Sample

The study investigated an organized semantic fluency task, (the Controlled Animal Fluency Task - CAFT) as a measure of executive functioning (EF) in adults, and the relationship with instrumental activities of daily living (IADL). Participants (N = 266) consisted of a clinical sample (n = 142) utilizing neuropsychological assessment data collected at an outpatient psychological center, and a community sample (n = 124). The clinical sample was a heterogeneous mixed neurological group including a variety of health conditions and comorbid anxiety and depression. The CAFT Animals by Size demonstrated a significant positive correlation with Category Fluency (r = .71, n = 142, p < .001) , Animal Fluency (r = .70, n = 142, p < .001), and with other, established neuropsychological measures. The CAFT Animals by Size condition demonstrated a significant moderate negative correlation with IADL for the sample as a whole (r = -.46, n = 248, p < .001), and for the clinical sample (r = -.38, n = 129, p < .001), but not for the community sample. In a hierarchical regression analysis, CAFT Animal by Size explained additional variance in IADL (ΔR2 = .15). In a hierarchical regression analysis predicting IADL with the control variables entered first, followed by Category Fluency, with CAFT Animal by Size entered last, CAFT Animals by Size did not make a significant additional contribution. A stepwise forward regression indicated Category Fluency, education, and Category Switching are better predictors of IADL than CAFT Animals by Size. Normative data for the CAFT were calculated separately for age groups and education levels. Simple logistic regression indicated CAFT Animal by Size was a significant predictor of clinical or community group membership. A second logistic regression analysis indicated the CAFT Animal by Size condition improved the prediction of membership in the clinical versus the community group, compared to the MMSE alone. Applications of the CAFT are discussed.
Paclitaxel as second and subsequent therapy for metastatic breast cancer: activity independent of prior anthracycline response.

PURPOSE Two phase II clinical trials were performed to determine efficacy and tolerability of paclitaxel (Taxol; Bristol-Myers Squibb Co, Wallingford, CT) and granulocyte colony-stimulating factor ([G-CSF] Neupogen; Amgen, Inc, Thousand Oaks, CA) as second or subsequent therapy for metastatic breast cancer. PATIENTS AND METHODS Paclitaxel plus G-CSF was administered as a second stage IV regimen to 25 patients with metastatic breast cancer at a dose of 250 mg/m2 intravenously over 24 hours. Fifty-two patients received paclitoxel plus G-CSF at 200 mg/m2 as a third or subsequent regimen (no restriction on number of prior regimens or on prior high-dose chemotherapy). All patients had received prior anthracycline treatment, and ultimately had progressive bidimensionally measurable disease. RESULTS Twenty-five of 76 patients (32.8%) had a major objective response (95% confidence interval [CI], 14% to 37%). The median duration of response was 7 months (range, 1 to 20+). Responses were as likely in patients with disease demonstrated to be unresponsive to anthracycline, ie, de novo resistance (11 of 37, or 30%) as in those with disease that once exhibited anthracycline sensitivity, ie, acquired resistance, (10 of 31, or 32%). G-CSF administration was associated with febrile neutropenic episodes in 36 of 402 cycles (9%) in 16 of 76 patients (21%). CONCLUSION Paclitaxel's clinically significant activity against metastatic breast cancer extends to patients with many prior chemotherapy regimens. The lack of impact of prior doxorubicin therapy on the likelihood of subsequent response to paclitaxel suggests an important role for this agent in the treatment of refractory metastatic breast cancer.
Alterations in Caveolin-1 Expression and Receptor-Operated Ca2+ Entry in the Aortas of Rats with Pulmonary Hypertension

Background/Aims: Alterations in intracellular Ca2+ concentration ([Ca2+]i) underlie the pathogenesis of various cardiovascular diseases. Caveolin-1 (Cav-1) is the primary functional protein associated with caveolae, which are invaginations in the plasma membrane, and is a regulator of [Ca2+]i signaling. Caveolae and Cav-1 increase the activity of store-operated Ca2+ channels (SOCC) in rat pulmonary arterial smooth muscle cells (PASMCs), and these enhancing effects were more pronounced in rats with pulmonary hypertension (PH). Classical transient receptor potential (TRPC) proteins are highly expressed in vascular smooth muscle cells, and these proteins form functional receptor-operated Ca2+ channels (ROCC) and SOCC in PASMCs. Previous studies suggested that functional and structural changes in aortas might occur during the pathological process of PH. Our data demonstrated that Cav-1 and TRPC were also abundant in the aorta smooth muscle cells (AoSMCs) of PH rats. However, previous PH research primarily focused on Ca2+ channels in pulmonary arteries, but not functional changes in Ca2+ channels in aortas. The contribution of Cav-1 of AoSMCs to alterations of Ca2+ signaling in aortic functions during the pathological process of PH has not been fully characterized. Therefore, this study investigated alterations in Cav-1 expression and the relationship of these changes to Ca2+ channels in AoSMCs of PH rats. Methods: The present study examined physiological caveolae and Cav-1 expression and characterized the function of altered Cav-1 expression in rat aortas with PH. Results: The appearance of caveolae with Cav-1 expression increased significantly in the aortas of rats with PH, but TRPC1 and TRPC6 expression was not altered. In vitro experiments demonstrated that caveolae contributed to phenylephrine, endothelin-1, and 1-oleoyl-2-acetyl-sn-glycerol (OAG)-induced aortic vasoreactivity, but KCl and cyclopiazonic acid had no effect, which suggests the vital ability of Cav-1 to regulate ROCC activity. The introduction of Cav-1 scaffolding domain peptide enhanced OAG-induced ROCC function in primary AoSMCs. Conclusion: Cav-1 is specifically associated with ROCC in aortas and plays a vital role in altering vasoreactivity, which affects cardiovascular diseases pathology. Caveolae and Cav-1 up-regulation may affect the function of ROCC in rat models of PH.
Cluster C Personality Disorders in Major Depressive Episodes: The Relationship Between Hostility and Suicidal Behavior

There is some evidence for an association between Cluster C Personality Disorders (CCPD) and suicidal behavior. We compared depressed inpatients with and without CCPD in terms of suicidal behavior and associated psychopathology. Cluster A or B personality disorder co-morbidity were exclusion criteria for both groups (cases and controls). Depressed inpatients with “pure” CCPD had higher levels of suicidal ideation but not more previous suicide attempts compared with patients without CCPD. Greater suicidal ideation in depressed patients with CCPD in our study was associated with more hostility. Future studies examining the relationship between suicidal ideation and hostility in CCPD may clarify whether treatment focused on hostility might be of use for decreasing suicidal ideation in depressed patients with CCPD (Spitzer, Williams, Gibbon et al., 1990).
Working memory matters : a series of case studies evaluating the effect of a working memory intervention in children with early onset otitis media

Otitis Media (glue ear) delays reading (Kindig & Richards, 2000) by impacting on phonological processing, and may affect working memory development (Mody et al, 1999). Reported links between working memory capacity and school success (Bourke & Adams, 2003; Gathercole, Pickering, Knight & Stegman, 2004), suggest that working memory has a crucial role in learning. Deficits have been linked to anxiety during task performance (Hadwin, Brogan & Stevenson, 2005) and low self-esteem (Alloway, Gathercole, Kirkwood & Elliott, 2009). Sixteen children aged seven to ten with a history of early onset Otitis Media, together with a comparison group of twelve children were assessed on a range of measures of phonological processing, single word and non-word reading, non-verbal reasoning and working memory, and an attitude to self and school rating scale, before and after working memory training. Semi-structured interviews and classroom observations of learning behaviours were used to elaborate the findings from the quantitative data. Significant differences were found between the groups before training in verbal and visuo-spatial short term and working memory, and non-word reading. Following training these differences were no longer significant. Performance in reading and phonological tasks was found to improve for both groups following training. Mean scores for responses to the learning attitudes rating scales were not significantly different before or after training, but large individual differences were found for children in both groups. Case studies are presented of individual children in the Otitis Media group. The results indicate that, as found in previous studies, a history of Otitis Media can result in weaknesses in phonological processes, memory and literacy development, and the original contribution of this study indicates that these may be ameliorated by a working memory intervention. Improvements in working memory did not appear to affect children’s overall learning identities but more positive feelings were found after training for several children.
Oxytocin blurs the self‐other distinction during trait judgments and reduces medial prefrontal cortex responses

The neuropeptide oxytocin (OXT) may act either to increase or blur the distinction between self and other and thereby promote either more selfish or altruistic behaviors. To attempt to distinguish between these two possibilities we performed a double‐blind, between‐subject, placebo‐controlled design study to investigate the effect of intranasal OXT on self and other (mother, classmate, or stranger) trait judgments in conjunction with functional magnetic resonance imaging. Results showed that OXT reduced response times for making both self and other judgments, but also reduced the accuracy of their subsequent recall, thereby abolishing the normal self‐bias observed in this task. OXT also abolished the positive correlation between response and self‐esteem scale scores seen in the PLC group, suggesting that its effects were strongest in individuals with higher levels of self‐esteem. A whole‐brain functional magnetic resonance imaging analysis revealed that OXT also reduced responses during both self and other trait judgments in the dorsal (dmPFC) and ventral (vmPFC) medial prefrontal cortex. A subsequent region of interest analysis revealed that behavioral performance and self‐esteem scale scores were associated with dmPFC activation and its functional connectivity with the anterior cingulate and between the vmPFC and posterior cingulate. Thus overall, while OXT may improve speed of decision making in self ‐vs. other trait judgments it also blunts the normal bias towards remembering self‐attributes and reduces mPFC responses and connectivity with other cortical midline regions involved in self‐processing. This is consistent with the view that OXT can reduce self‐centered behavior. Hum Brain Mapp 37:2512–2527, 2016. © 2016 Wiley Periodicals, Inc.
Appropriateness of phacoemulsification in Spain.

OBJECTIVE To evaluate the appropriateness of phacoemulsification procedures performed in four Spanish regions, applying criteria developed by means of RAND/UCLA methodology. DESIGN Prospective observational study. SETTING Seventeen public teaching hospitals in four regions of Spain. PARTICIPANTS Patients on waiting list to undergo cataract extraction by phacoemulsification. INTERVENTION Cataract surgery by phacoemulsification. MAIN OUTCOME MEASURE Level of appropriateness of each intervention, according to criteria developed by means of the RAND/UCLA appropriateness methodology. RESULTS Among the 5442 analysed patients the indication of phacoemulsification was appropriate in 69.6%, inappropriate in 7.3% and uncertain in 23.0%. Presence of ocular comorbidity, lack of cataract-induced visual function limitation, anticipated postoperative visual acuity of <0.5, preoperative visual acuity of >0.1 and high surgical complexity were associated with inappropriateness. CONCLUSIONS Some clinical characteristics, when present, make it especially important to obtain a careful assessment of the risks and benefits of surgery. Consideration of these characteristics may improve the appropriateness of phacoemulsification.