Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of Tillering Node Proteins Differentially Accumulated in Barley Recombinant Inbred Lines with Different Juvenile Growth Habits

Barley (Hordeum vulgare L.) is an important cereal crop grown for both the feed and malting industries. The allelic dwarfing gene sdw1/denso has been used throughout the world to develop commercial barley varieties. Proteomic analysis offers a new approach to identify a broad spectrum of genes that are expressed in the living system. Two-dimensional electrophoresis and mass spectrometry were applied to investigate changes in protein abundance associated with different juvenile growth habit as effect of the denso locus in barley homozygous lines derived from a Maresi × Pomo cross combination. A total of 31 protein spots were revealed that demonstrate quantitative differences in protein abundance between the analyzed plants with different juvenile growth habit, and these protein spots were selected to be identified by mass spectrometry. Identification was successful for 27 spots, and functional annotations of proteins revealed that most of them are involved in metabolism and disease/defense-related processes. Functions of the identified proteins and their probable influence on the growth habit in barley are discussed.
Efficacy and moderators of a family group cognitive-behavioral preventive intervention for children of parents with depression.

OBJECTIVE Building on an earlier study (Compas, Forehand, Thigpen, et al., 2011), tests of main effects and potential moderators of a family group cognitive-behavioral (FGCB) preventive intervention for children of parents with a history of depression are reported. METHOD Assessed a sample of 180 families (242 children ages 9-15 years) in a randomized controlled trial assessed at 2, 6, 12, 18 and 24 months after baseline. RESULTS Significant effects favoring the FGCB intervention over a written information comparison condition were found on measures of children's symptoms of depression, mixed anxiety/depression, internalizing problems, and externalizing problems, with multiple effects maintained at 18 and 24 months, and on incidence of child episodes of major depressive disorder over the 24 months. Effects were stronger for child self-reports than for parent reports. Minimal evidence was found for child age, child gender, parental education, parental depressive symptoms, or presence of a current parental depressive episode at baseline as moderators of the FGCB intervention. CONCLUSIONS The findings provide support for sustained and robust effects of this preventive intervention.
Producing Contextually Appropriate Intonation is an Information-State Based Dialogue System

Our goal is to improve the contextual appropriateness of spoken output in a dialogue system. We explore the use of the information state to determine the information structure of system utterances. We concentrate on the realization of information structure by intonation. We present the results of evaluating the contextual appropriateness of varied system output produced with a text-to-speech synthesis system that supports intonation annotation.
COMPUTER SIMULATIONS OF PARTICLE DEPOSITION IN THE LUNGS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS

Epidemiology data show that mortality rates for chronic obstructive pulmonary disease (COPD) patients increase with an increase in concentration of ambient particulate matter (PM). This is not seen for normal subjects. Therefore, the U.S. Environmental Protection Agency (EPA) has identified COPD patients as a susceptible subpopulation to be considered in regulatory standards. In the present study, a computer model was used to calculate deposition fractions of PM within the lungs of COPD patients. The morphology of COPD lungs was characterized by two distinct components: obstruction of airways (chronic bronchitis component), and degeneration of alveolar structure (emphysema component). The chronic bronchitis component was modeled by reducing airway diameters using airway resistance measurements in vivo, and the emphysema component was modeled by increasing alveolar volumes. Calculated results were compared with experimental data obtained from COPD patients for controlled breathing trials (tidal volume of 500 ml, respiratory time of 1 s) with a particle size of 1 µm. The model successfully depicts PM deposition patterns and their dependence on the severity of disease. The findings indicate that airway obstructions are the main cause for increased deposition in the COPD lung.
Addressing Ethnic and Gender Differences in Advanced Placement Calculus (AB) Exam Scores

ii Dedication.iii Acknowledgements.iv List of Tables.ix Chapter 1: Introduction.1 Background, Context, History, and Conceptual Framework for the Problem.2 Statement of the Problem.5 Purpose of the Study.6 Research Questions.7 Rationale, Relevance, and Significance of the Study.8 Definition of Terms.9 Assumptions.11 Delimitations.11 Limitations.12 Summary.12 Chapter 2: Literature Review.14 Brief History of Advanced Placement.17 Conceptual Framework.18 A brief history of Opportunity to Learn Theory.18 Measurement of Opportunity to Learn . 20 Opportunity to Learn Theory summary.21 Review of Research Literature.21
Trapped modes in a two-layer fluid

Trapped-mode frequencies are computed for submerged horizontal circular cylinders in a two-layer fluid consisting of a finite layer bounded above by a free surface and below by an infinite layer of greater density. Two separate cases are examined. First we consider waves which propagate along the top of a single cylinder at frequencies below the cut-off for wave propagation away from the cylinder, and find modes where the motion is concentrated around the interface, modes which are concentrated around the free surface, and modes which involve significant motion of both the interface and the free surface. Secondly, we compute modes above the cut-off for a pair of submerged cylinders in the lower fluid.
Family history and BRCA1/BRCA2 status among Japanese ovarian cancer patients and occult cancer in a BRCA1 mutant case.

BACKGROUND This study aimed to examine family history among Japanese ovarian cancer patients and to investigate the TP53 status of fallopian tube epithelial and ovarian cancer cells in a Japanese BRCA1 mutant case that may be associated with the transformed state in hereditary ovarian cancer. METHODS One hundred and two primary ovarian cancer patients were retrospectively evaluated in this cross-sectional study. The family history of cancer was determined in probands. In a BRCA1 mutant case, p53 immunostaining and direct sequencing, followed by laser-capture microdissection, were performed for the fallopian tube, considered the origin of ovarian cancer. RESULTS Nine of 102 (8.8%) families were regarded as having hereditary breast-ovarian cancer syndrome, two families (2.0%) were diagnosed with Lynch syndrome and six patients harbored BRCA1 or BRCA2 mutations. One case underwent risk-reductive salpingo-oophorectomy as a BRCA1 mutant carrier was retrospectively diagnosed as occult cancer. Common TP53 mutations were detected in cancer and fallopian tube epithelial cells in the case. CONCLUSIONS Here, we integrate family cancer history and histology in ovarian cancer cases as well as TP53 status in a BRCA1 mutant case into a discussion regarding carcinogenesis in a Japanese population. The TP53 status for the BRCA1 mutant case examined here supports the recently proposed theory that ovarian cancer develops because of BRCA1 or BRCA2 inactivation and/or TP53 mutations.
Selection of Valid Reference Genes for Reverse Transcription Quantitative PCR Analysis in Heliconius numata (Lepidoptera: Nymphalidae)

Identifying the genetic basis of adaptive variation is challenging in non-model organisms and quantitative real time PCR. is a useful tool for validating predictions regarding the expression of candidate genes. However, comparing expression levels in different conditions requires rigorous experimental design and statistical analyses. Here, we focused on the neotropical passion-vine butterflies Heliconius, non-model species studied in evolutionary biology for their adaptive variation in wing color patterns involved in mimicry and in the signaling of their toxicity to predators. We aimed at selecting stable reference genes to be used for normalization of gene expression data in RT-qPCR analyses from developing wing discs according to the minimal guidelines described in Minimum Information for publication of Quantitative Real-Time PCR Experiments (MIQE). To design internal RT-qPCR controls, we studied the stability of expression of nine candidate reference genes (actin, annexin, eF1α, FK506BP, PolyABP, PolyUBQ, RpL3, RPS3A, and tubulin) at two developmental stages (prepupal and pupal) using three widely used programs (GeNorm, NormFinder and BestKeeper). Results showed that, despite differences in statistical methods, genes RpL3, eF1α, polyABP, and annexin were stably expressed in wing discs in late larval and pupal stages of Heliconius numata. This combination of genes may be used as a reference for a reliable study of differential expression in wings for instance for genes involved in important phenotypic variation, such as wing color pattern variation. Through this example, we provide general useful technical recommendations as well as relevant statistical strategies for evolutionary biologists aiming to identify candidate-genes involved adaptive variation in non-model organisms.
Reaching Higher

* Introduction * I. Reframing the Debate: What Children Can Become *1. Colliding Expectations of Family and School *2. Turning Points in Research on Expectations: Toward an Ecological Paradigm *3. Revisiting Educational Self-Fulfilling Prophecies * II. Expectations in Classrooms: Through the Eyes of Students *4. Children Talk about Expectations for Achievement *5. Differences among Classroom Achievement Cultures *6. Children's Lives in Contrasting Classrooms *7. Achievement Histories of Vulnerability and Resilience * III. Expectations in Systems: Through the Eyes of Educators *8. Changing a Stratified School Culture *9. A School Culture for the Fullest Development *10. Achievement Cultures for University Faculty * Conclusion * References * Acknowledgments * Index
Research of 2DPCA principal component uncertainty in face recognition

This paper studied 2DPCA ( two-dimensional principal component analysis ) principal component feature vectors for face recognition, it found that different principal component had the different role, and then it studied 2DPCA principal component uncertainty, it is good to distinguish 2DPCA principal component role. Using uncertainty knowledge to calculate the weights of 2DPCA principal components, and the last weights was found by optimization of weights, the principal components were processed by using weighted in the process of recognition. ORL face images were used to test the algorithm, the results indicate that the algorithm has good recognition performance.
The Development of a Reading Comprehension Test

Reading comprehension has an important place in lifelong learning. It is an interactive process between the reader and the text. Students need reading comprehension skills at all educational levels and for all school subjects. Determining the level of students' reading comprehension skills is the subject of testing and evaluation. Tests used to measure students' success are expected to provide accurate and reliable information. Therefore, the aim of this study is to develop a valid and reliable reading comprehension test appropriate for fourth grade reading comprehension learning outcomes. The participants in the study were 245 fourth graders from three schools at low, middle and high socioeconomic levels in the central district of Kars. Items with discrimination indices below . 30 and those that did not differ by 27% in the upper and lower groups on the independent groups t-test were excluded from the test. The difficulty indices of the test items ranged from . 37 to . 79. The KR-20 reliability coefficient was found to be 0.83, indicating that this multiple choice reading comprehension test is valid and reliable.
Context-Specific Grasp Movement Representation in Macaque Ventral Premotor Cortex

Hand grasping requires the transformation of sensory signals to hand movements. Neurons in area F5 (ventral premotor cortex) represent specific grasp movements (e.g., precision grip) as well as object features like orientation, and are involved in movement preparation and execution. Here, we examined how F5 neurons represent context-dependent grasping actions in macaques. We used a delayed grasping task in which animals grasped a handle either with a power or a precision grip depending on context information. Additionally, object orientation was varied to investigate how visual object features are integrated with context information. In 420 neurons from two animals, object orientation and grip type were equally encoded during the instruction epoch (27% and 26% of all cells, respectively). While orientation representation dropped during movement execution, grip type representation increased (20% vs 43%). According to tuning onset and offset, we classified neurons as sensory, sensorimotor, or motor. Grip type tuning was predominantly sensorimotor (28%) or motor (25%), whereas orientation-tuned cells were mainly sensory (11%) or sensorimotor (15%) and often also represented grip type (86%). Conversely, only 44% of grip-type tuned cells were also orientation-tuned. Furthermore, we found marked differences in the incidence of preferred conditions (power vs precision grips and middle vs extreme orientations) and in the anatomical distribution of the various cell classes. These results reveal important differences in how grip type and object orientation is processed in F5 and suggest that anatomically and functionally separable cell classes collaborate to generate hand grasping commands.
Regulatory arbitrage of risk measures

We introduce the regulatory arbitrage of risk measures, one of the key considerations in choosing a suitable risk measure to use in banking regulation. A regulatory arbitrage is the amount of capital requirement reduced by splitting a financial risk into several fragments, regulated via a risk measure separately. Coherent risk measures by definition are free of regulatory arbitrage; dividing risks will not reduce the total capital requirement under a coherent risk measure. However, risk measures in practical use, such as the Value-at-Risk (VaR), are often not coherent and the magnitude of their regulatory arbitrage is then of significant importance. We quantify the regulatory arbitrage of risk measures in a rigorous mathematical framework, and categorize risk measures into three classes: free of regulatory arbitrage, of limited regulatory arbitrage, and of infinite regulatory arbitrage. We provide explicit results to characterize the regulatory arbitrage for general classes of risk measures, including distortion risk measures and convex risk measures. Several examples of risk measures of limited regulatory arbitrage are illustrated, as possible alternatives for coherent risk measures.
Negotiating the Boundaries of Parental School Engagement: The Role of Social Space and Symbolic Capital in Urban Teachers’ Perspectives

Background/Context Research has documented the benefits of family and parental involvement in children's schooling, both developmentally and across domains. Classroom teachers play pivotal roles in establishing and maintaining home–school partnerships because of their sustained contact with children. Despite this, few studies have examined empirically how urban teachers actually define their own roles in helping schools to connect with diverse families and, especially, the power asymmetries that exist between families, teachers, and schools themselves in a climate of increased accountability and scrutiny of urban public schools. Purpose/Objectives Using Bourdieu's concepts of social space and symbolic capital, this qualitative study examined urban teachers’ perspectives on their roles in facilitating effective partnerships with diverse families and the ways that issues of power, authority, and the need for boundaries in home–school relationships were expressed in their discourse. Setting Data were gathered at four public schools in a major metropolitan city in the Northeast. All were racially/ethnically diverse (more than 50% non-White in all schools) and served high percentages of low-socioeconomic-status families. Participants Participants were 44 classroom teachers. All but two teachers were female; participants were racially diverse (42% White, 42% Black, 16% Latino/a) and had been teaching for an average of 17.25 years. Research Design Qualitative focus group interviews were conducted with teachers at each participating school site over the course of six months. Data Collection/Analysis Focus group data were analyzed using qualitative content analytic techniques. Findings/Results Analyses generated three themes that illustrated the powerful but contradictory positioning of teachers in facilitating authentic partnerships with families—(a) creating responsive relationships, (b) casting engagement as education, and (c) creating varied and tailored opportunities—yet also revealed teachers’ assertions of power and authority, most often expressed as a need for boundaries between home and school. Conclusions/Recommendations Findings support a progressive approach to family engagement and educator resistance whereby teachers engage in collaborative advocacy with urban families to reclaim the notion of teaching as a public service aimed at the promotion of equitable, accessible, and culturally responsive schools.
Modeling the distribution of day-ahead electricity returns: a comparison

This paper contributes to the characterization of the probability density of the price returns in some European day-ahead electricity markets (NordPool, APX, Powernext) by fitting flexible and general families of distributions, such as the α-stable, Normal Inverse Gaussian (NIG), Exponential Power (EP), and Asymmetric Exponential Power (AEP) distributions, and comparing their goodness of fit. The α-stable and the NIG systematically outperform the EP and AEP models, but the tail behavior and the skewness are sensitive to the definition of the returns and to the deseasonalization methods. In particular, the logarithmic transform and volatility rescaling tend to dampen the extreme returns.
Study of Camelpox Virus Pathogenesis in Athymic Nude Mice

Camelpox virus (CMLV) is the closest known orthopoxvirus genetically related to variola virus. So far, CMLV was restricted to camelids but, recently, three human cases of camelpox have been described in India, highlighting the need to pursue research on its pathogenesis, which has been hampered by the lack of small animal models. Here, we confirm that NMRI immunocompetent mice are resistant to intranasal (i.n.) CMLV infection. However, we demonstrate that CMLV induced a severe disease following i.n. challenge of athymic nude mice, which was accompanied with a failure in gaining weight, leading to euthanasia of the animals. On the other hand, intracutaneous (i.c.) infection resulted in disease development without impacting the body weight evolution. CMLV replication in tissues and body fluids was confirmed in the two models. We further analyzed innate immune and B cell responses induced in the spleen and draining lymph nodes after exposure to CMLV. In both models, strong increases in CD11b+F4/80+ macrophages were seen in the spleen, while neutrophils, NK and B cell responses varied between the routes of infection. In the lymph nodes, the magnitude of CD11c+CD8α+ lymphoid and CD11c+CD11b+ myeloid dendritic cell responses increased in i.n. challenged animals. Analysis of cytokine profiles revealed significant increases of interleukin (IL)-6 and IL-18 in the sera of infected animals, while those of other cytokines were similar to uninfected controls. The efficacy of two antivirals (cidofovir or HPMPC, and its 2, 6-diaminopurine analog) was evaluated in both models. HPMPC was the most effective molecule affording 100% protection from morbidity. It appeared that both treatments did not affect immune cell responses or cytokine expression. In conclusion, we demonstrated that immunodeficient mice are permissive for CMLV propagation. These results provide a basis for studying the pathogenesis of CMLV, as well as for evaluating potential antiviral therapies in an immunodeficiency context.
ISOTOPIC COMPOSITION OF LIGHT NUCLEI IN COSMIC RAYS: RESULTS FROM AMS-01

The variety of isotopes in cosmic rays allows us to study different aspects of the processes that cosmic rays undergo between the time they are produced and the time of their arrival in the heliosphere. In this paper, we present measurements of the isotopic ratios 2H/4He, 3He/4He, 6Li/7Li, 7Be/(9Be+10Be), and 10B/11B in the range 0.2–1.4 GeV of kinetic energy per nucleon. The measurements are based on the data collected by the Alpha Magnetic Spectrometer, AMS-01, during the STS-91 flight in 1998 June.
Validation of Emotional Intelligence's Scale inIndian Context

The intention of this paper is to exhibit the reliability and validity of Emotional Intelligence scale developed by Goleman (1998). A sample of 549 respondents filled the emotional intelligence scale. This scale contains 32 statements describing the individual’s emotional stability and how he or she is capable of manage their emotions. A person with high emotional intelligence supposes to manage emotions in every situation and face other individual’s unpredictable emotions as well. Emotional intelligence now days very important at work place to develop understandings between employees. Statements include in this emotional intelligence’s scale represent the emotional stability and managing emotions. This paper tries to represent this scales validity and reliability in Indian context.
Contribution of Common Genetic Variants to Obesity and Obesity-Related Traits in Mexican Children and Adults

Background Several studies have identified multiple obesity-associated loci mainly in European populations. However, their contribution to obesity in other ethnicities such as Mexicans is largely unknown. The aim of this study was to examine 26 obesity-associated single-nucleotide polymorphisms (SNP) in a sample of Mexican mestizos. Methods 9 SNPs in biological candidate genes showing replications (PPARG, ADRB3, ADRB2, LEPR, GNB3, UCP3, ADIPOQ, UCP2, and NR3C1), and 17 SNPs in or near genes associated with obesity in first, second and third wave GWAS (INSIG2, FTO, MC4R, TMEM18, FAIM2/BCDIN3, BDNF, SH2B1, GNPDA2, NEGR1, KCTD15, SEC16B/RASAL2, NPC1, SFRF10/ETV5, MAF, PRL, MTCH2, and PTER) were genotyped in 1,156 unrelated Mexican-Mestizos including 683 cases (441 obese class I/II and 242 obese class III) and 473 normal-weight controls. In a second stage we selected 12 of the SNPs showing nominal associations with obesity, to seek associations with quantitative obesity-related traits in 3 cohorts including 1,218 Mexican Mestizo children, 945 Mexican Mestizo adults, and 543 Indigenous Mexican adults. Results After adjusting for age, sex and admixture, significant associations with obesity were found for 6 genes in the case-control study (ADIPOQ, FTO, TMEM18, INSIG2, FAIM2/BCDIN3 and BDNF). In addition, SH2B1 was associated only with class I/II obesity and MC4R only with class III obesity. SNPs located at or near FAIM2/BCDIN3, TMEM18, INSIG2, GNPDA2 and SEC16B/RASAL2 were significantly associated with BMI and/or WC in the combined analysis of Mexican-mestizo children and adults, and FTO locus was significantly associated with increased BMI in Indigenous Mexican populations. Conclusions Our findings replicate the association of 8 obesity-related SNPs with obesity risk in Mexican adults, and confirm the role of some of these SNPs in BMI in Mexican adults and children.