Miracle-dz/UniFAR-FTUs huggingface dataset:
Driving E-Business Excellence

In trying to bring about e-business transformation, companies have paid too much attention to technology ? as if adding the right software or hardware could, on its own, bring about miracles. But systems do not work in a vacuum, and senior managers would do well to recognize the complementary nature of technology, business processes and e-business readiness throughout the value chain, from their suppliers to their customers. By taking a more holistic view, executives can turn these facets of a company's operations into the drivers of e-business excellence. To help company leaders see the bigger picture, authors Anitesh Barua, Prabhudev Konana, Andrew B. Whinston and Fang Yin of the University of Texas at Austin's McCombs School of Business developed a research-backed model of e-business value creation. The model's premise is deceptively simple: that proper development of e-business drivers will lead to operational excellence, which will, in turn, generate improved financial performance. The authors explain that if managers are to lead a successful digital transformation, they must carefully track such e-business operational measures as the percentage of goods purchased online from suppliers and the percentage of customer-service requests handled through the Web site. Companies that scored high on those (and other) measures in the authors' study also enjoyed significant increases in revenue per employee, gross profit margin, return on assets and return on investments. Once managers understand their company's relative degree of e-business operational excellence, they can develop the drivers that will raise those scores. The authors guide readers through the eight drivers their research uncovered, from mastering supplier-related processes to optimizing IT applications aimed at customers.
E-SAP: Efficient-Strong Authentication Protocol for Healthcare Applications Using Wireless Medical Sensor Networks

A wireless medical sensor network (WMSN) can sense humans’ physiological signs without sacrificing patient comfort and transmit patient vital signs to health professionals’ hand-held devices. The patient physiological data are highly sensitive and WMSNs are extremely vulnerable to many attacks. Therefore, it must be ensured that patients’ medical signs are not exposed to unauthorized users. Consequently, strong user authentication is the main concern for the success and large scale deployment of WMSNs. In this regard, this paper presents an efficient, strong authentication protocol, named E-SAP, for healthcare application using WMSNs. The proposed E-SAP includes: (1) a two-factor (i.e., password and smartcard) professional authentication; (2) mutual authentication between the professional and the medical sensor; (3) symmetric encryption/decryption for providing message confidentiality; (4) establishment of a secure session key at the end of authentication; and (5) professionals can change their password. Further, the proposed protocol requires three message exchanges between the professional, medical sensor node and gateway node, and achieves efficiency (i.e., low computation and communication cost). Through the formal analysis, security analysis and performance analysis, we demonstrate that E-SAP is more secure against many practical attacks, and allows a tradeoff between the security and the performance cost for healthcare application using WMSNs.
Provided for Non-commercial Research and Educational Use Only. Not for Reproduction, Distribution or Commercial Use. the Role of Body Size in Complex Food Webs: a Cold Case Author's Personal Copy

research and educational use including without limitation use in instruction at your institution, sending it to specific colleagues who know you, and providing a copy to your institution's administrator. All other uses, reproduction and distribution, including without limitation commercial reprints, selling or licensing copies or access, or posting on open internet sites, your personal or institution's website or repository, are prohibited. For exceptions, permission may be sought for such use through Elsevier's permissions site at: ABSTRACT Human-induced habitat destruction, overexploitation, introduction of alien species and climate change are causing species to go extinct at unprecedented rates, from local to global scales. There are growing concerns that these kinds of disturbances alter important functions of ecosystems. Our current understanding is that key parameters of a community (e.g. its functional diversity, species composition, and presence/absence of vulnerable species) reflect an ecological network's ability to resist or rebound from change in response to pressures and disturbances, such as species loss. If the food web structure is relatively simple, we can analyse the roles of different species interactions in determining how environmental impacts translate into species loss. However, when ecosystems harbour species-rich communities, as is the case in most natural systems, then the complex network of ecological interactions makes it a far more challenging task to perceive how species' functional roles influence the consequences of species loss. One approach to deal with such complexity is to focus on the functional traits of species in order to identify their respective roles: for instance, large species seem to be more susceptible to extinction than smaller species. Here, we introduce and analyse the marine food web from the high Antarctic Weddell Sea Shelf to illustrate the role of species traits in relation to network robustness of this complex food web. Our approach was threefold: firstly, we applied a new classification system to all species, grouping them by traits other than body size; secondly, we tested the relationship between body size and food web parameters within and across these groups and finally, we calculated food web robustness. We addressed questions regarding (i) patterns of species functional/trophic roles, (ii) relationships between species functional roles and body size and (iii) the role of species body size in terms of network robustness. Our results show that when 182 UTE JACOB ET AL. analyzing relationships between trophic structure, body size and network structure, the diversity of predatory species types needs to be …
The 2014 Indian general election on Twitter: an analysis of changing political traditions

This study investigates how politicians and citizens cooperate to create an e-democracy based on information dissemination and political awareness in an ICT environment, especially during elections. This research is conducted in the Indian context, where new ICT channels, such as Facebook and Twitter, were extensively used for campaigning and citizen engagement prior to elections. We downloaded 98,396 tweets posted by the official Twitter accounts of the top ten political parties during a two month period prior to election and conducted a three-level analysis to identify the overall trend in usage, the interactive characteristics of tweets and the functions driving the Twitter usage of political parties. Our findings show that the more successful parties used Twitter to push timely updates on online and offline campaign activities, to their followers. The exemplary use of Twitter for campaigns was by the Bharatiya Janta Party (BJP) Twitter account for interacting with the public, and by the Aam Aadmi Party (AAP) account for self-promotion and highlighting its party manifesto. Further, we identify the new paradigms created by political parties to engage and inform voters, driven on modern ICT. Our study is the first in analyzing Twitter usage by Indian political parties, and its findings corroborate seminal research in other developing countries.
A Neurocomputational account of the role of contour facilitation in brightness perception

A new filling-in model is proposed in order to account for challenging brightness illusions, where inducing background elements are spatially separated from the gray target such as dungeon, cube and grating illusions, bullseye display and ring patterns. This model implements the simple idea that neural response to low-contrast contour is enhanced (facilitated) by the presence of collinear or parallel high-contrast contours in its wider neighborhood. Contour facilitation is achieved via dendritic inhibition, which enables the computation of maximum function among inputs to the node. Recurrent application of maximum function leads to the propagation of the neural signal along collinear or parallel contour segments. When a strong global-contour signal is accompanied with a weak local-contour signal at the same location, conditions are met to produce brightness assimilation within the Filling-in Layer. Computer simulations showed that the model correctly predicts brightness appearance in all of the aforementioned illusions as well as in White's effect, Benary's cross, Todorović's illusion, checkerboard contrast, contrast-contrast illusion and various variations of the White's effect. The proposed model offers new insights on how geometric factors (contour colinearity or parallelism), together with contrast magnitude contribute to the brightness perception.
Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.

OBJECTIVES Invasive mould infections are associated with a high mortality rate and the emergence of MDR moulds is of particular concern. Calcineurin and its chaperone, the heat shock protein 90 (Hsp90), represent an important pathway for fungal virulence that can be targeted at different levels. We investigated the antifungal activity of compounds directly or indirectly targeting the Hsp90-calcineurin axis against different mould species. METHODS The in vitro antifungal activity of the anticalcineurin drug FK506 (tacrolimus), the Hsp90 inhibitor geldanamycin, the lysine deacetylase inhibitor trichostatin A and the Hsp70 inhibitor pifithrin-μ was assessed by the standard broth dilution method against 62 clinical isolates of Aspergillus spp. and non-Aspergillus moulds (Mucoromycotina, Fusarium spp., Scedosporium spp., Purpureocillium/Paecilomyces spp. and Scopulariopsis spp.) RESULTS FK506 had variable antifungal activity against different Aspergillus spp. and was particularly active against Mucor spp. Geldanamycin had moderate antifungal activity against Fusarium spp. and Paecilomyces variotii. Importantly, trichostatin A had good activity against the triazole-resistant Aspergillus ustus and the amphotericin B-resistant Aspergillus terreus as well as the MDR Scedosporium prolificans. Moreover, trichostatin A exhibited synergistic interactions with caspofungin against A. ustus and with geldanamycin against Rhizopus spp. for which none of the other agents showed activity. Pifithrin-μ exhibited little antifungal activity. CONCLUSIONS Targeting the Hsp90-calcineurin axis at different levels resulted in distinct patterns of susceptibility among different fungal species. Lysine deacetylase inhibition may represent a promising novel antifungal strategy against emerging resistant moulds.
A Bacillus subtilis Gene Induced by Cold Shock Encodes a Membrane Phospholipid Desaturase

ABSTRACT Bacillus subtilis grown at 37°C synthesizes saturated fatty acids with only traces of unsaturated fatty acids (UFAs). However, when cultures growing at 37°C are transferred to 20°C, UFA synthesis is induced. We report the identification and characterization of the gene encoding the fatty acid desaturase of B. subtilis. This gene, called des, was isolated by complementation of Escherichia coli strains with mutations in either of two different genes of UFA synthesis. The desgene encodes a polypeptide of 352 amino acid residues containing the three conserved histidine cluster motifs and two putative membrane-spanning domains characteristic of the membrane-bound desaturases of plants and cyanobacteria. Expression of thedes gene in E. coli resulted in desaturation of palmitic acid moieties of the membrane phospholipids to give the novel mono-UFA cis-5-hexadecenoic acid, indicating that theB. subtilis des gene product is a Δ5 acyl-lipid desaturase. The des gene was disrupted, and the resulting null mutant strains were unable to synthesize UFAs upon a shift to low growth temperatures. The des null mutant strain grew as well as its congenic parent at 20 or 37°C but showed severely reduced survival during stationary phase. Analysis of operon fusions in which the des promoter directed the synthesis of alacZ reporter gene showed that des expression is repressed at 37°C, but a shift of cultures from 37 to 20°C resulted in a 10- to 15-fold increase in transcription. This is the first report of a membrane phospholipid desaturase in a nonphotosynthetic organism and the first direct evidence for cold induction of a desaturase.
Contemporary treatment of children with critical and near-fatal asthma

Asthma is the most common chronic illness in childhood. Although the vast majority of children with acute asthma exacerbations do not require critical care, some fail to respond to standard treatment and require escalation of support. Children with critical or near-fatal asthma require close monitoring for deterioration and may require aggressive treatment strategies. This review examines the available evidence supporting therapies for critical and near-fatal asthma and summarizes the contemporary clinical care of these children. Typical treatment includes parenteral corticosteroids and inhaled or intravenous beta-agonist drugs. For children with an inadequate response to standard therapy, inhaled ipratropium bromide, intravenous magnesium sulfate, methylxanthines, helium-oxygen mixtures, and non-invasive mechanical support can be used. Patients with progressive respiratory failure benefit from mechanical ventilation with a strategy that employs large tidal volumes and low ventilator rates to minimize dynamic hyperinflation, barotrauma, and hypotension. Sedatives, analgesics and a neuromuscular blocker are often necessary in the early phase of treatment to facilitate a state of controlled hypoventilation and permissive hypercapnia. Patients who fail to improve with mechanical ventilation may be considered for less common approaches, such as inhaled anesthetics, bronchoscopy, and extracorporeal life support. This contemporary approach has resulted in extremely low mortality rates, even in children requiring mechanical support.
Decreased ID2 Promotes Metastatic Potentials of Hepatocellular Carcinoma by Altering Secretion of Vascular Endothelial Growth Factor

Purpose: We aimed to explore the molecular and biological functions of Inhibitor of DNA binding/differentiation 2 (ID2), which was found to be responsible for portal vein invasion of hepatocellular carcinoma (HCC). Experimental Design: We measured ID2 mRNA levels in 92 HCC patients by real-time reverse transcription-PCR and examined the relation to clinicopathologic features. To clarify the precise roles of ID2, we did in vitro analysis with expression vectors and small interfering RNAs. Effects of ID2 on cell invasive potential and expression of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor-1α were analyzed by Matrigel-coated invasion chamber, ELISA, and Western blot analysis, respectively. Results:ID2 mRNA level correlated inversely with portal vein invasion (P < 0.001), tumor-node-metastasis stage (P < 0.001), tumor size (P < 0.001), and early intrahepatic recurrence (P < 0.05). When limited to a cohort of hepatitis C virus–related HCCs, patients with low levels of ID2 had significantly shorter disease-free survival time than those with high levels of ID2. Invasive potential of cells transfected with ID2 expression vector was lower than that of empty vector–transfected cells. Cells overexpressing ID2 also showed decreased VEGF secretion and hypoxia-inducible factor-1α protein levels. The results of ID2-knockdown experiments were opposite to those of ID2 overexpression experiments. Conclusions: On the basis of our clinical and in vitro data, we suggest that ID2 plays a significant role in the metastatic process during progression of HCC. This action might be explained, at least in part, by altered cell mobility due to decreased secretion of VEGF.
Hate speech harms: a social justice discussion of disabled Norwegians’ experiences

Abstract This article presents findings from a survey on hate speech reported by disabled people in Norway. Previous British and American research shows that disabled people are more likely than their non-disabled peers to be the victims of hate speech and hate crime. In our study, 38% reported at least one experience of hate speech during the previous 12 months. The respondents reported a wide range of consequences of hate speech related to psychological, social and societal issues. The findings reveal that people place restrictions on their own lives as a result of being exposed to hate speech, including raising their opinion in public debates. Drawing on the work of Nancy Fraser, we discuss the mechanisms that prevent disabled people from participating in society on equal terms. We conclude that to combat hate speech, transformative strategies need to be applied.
Characterization and properties of weakly optimal entanglement witnesses

We present an analysis of the properties and characteristics of weakly optimal entanglement witnesses, that is witnesses whose expectation value vanishes on at least one product vector. Any weakly optimal entanglement witness can be written as the form of $W^{wopt}=\sigma-c_{\sigma}^{max} I$, where $c_{\sigma}^{max}$ is a non-negative number and $I$ is the identity matrix. We show the relation between the weakly optimal witness $W^{wopt}$ and the eigenvalues of the separable states $\sigma$. Further we give an application of weakly optimal witnesses for constructing entanglement witnesses in a larger Hilbert space by extending the result of [P. Badzi\c{a}g {\it et al}, Phys. Rev. A {\bf 88}, 010301(R) (2013)], and we examine their geometric properties.
Fitting Hierarchical Holographic Modeling into the Theory of Scenario Structuring and a Resulting Refinement to the Quantitative Definition of Risk

A point of view is suggested from which the Hierarchical Holographic Modeling (HHM) method can be seen as one more method within the Theory of Scenario Structuring (TSS), which is that part of Quantitative Risk Assessment having to do with the task of identifying the set of risk scenarios. Seen in this way, HHM brings strongly to our attention the fact that different methods within TSS can result in different sets of risk scenarios for the same underlying problem. Although this is not a problem practically, it is a bit awkward conceptually from the standpoint of the “set of triplets” definition of risk, in which the scenario set is part of the definition. Accordingly, the present article suggests a refinement to the set of triplets definition, which removes the specific set of scenarios, found by any of the TSS methods, from the definition of risk and casts it, instead, as an approximation to the “true” set of scenarios that is native to the problem at hand and not affected by the TSS method used.
Women, Men and News

In the twenty-teens, there are increasing numbers of women occupying executive positions in politics, business and the law but their words and actions rarely make the front page. In this article, we draw on data collected as part of the 2015 Global Media Monitoring Project (GMMP) and focus on England, Scotland, Wales and the Republic of Ireland. Since the first GMMP in 1995, there has been a slow but steady rise in the proportion of women who feature, report or present the news (now at 24 per cent), but that increase is a mere 7 per cent over 20 years. Not only is there a problem with visibility but our data also suggest that when women are present, their contributions are often confined to the realm of the private as they speak as citizens rather than experts and in stories about health but not politics. Just over a third of the media professionals we coded were women and older women are almost entirely missing from the media scene. Citizens and democracy more generally are poorly served by a news media which privileges men’s voices, actions and views over the other 51 per cent of the population: we surely deserve better.
Journalistic construction of congruence: Chinese media’s representation of common but differentiated responsibilities in environmental protection

This research clarifies China’s mediated international communication of its responsibility in environmental protection under the principle of common but differentiated responsibilities. The topic is explored within the context of China’s media ‘going global’ project, a key initiative of its soft power projection. Gauged by the notion of cultural and political congruence, this study also compares China’s journalistic discourse with those in the United States and the United Kingdom. This study found that Chinese mainstream media achieved a certain degree of congruence in media representations of China’s responsibility with its Western counterparts. Chinese media constructed the notion of responsibility in a mixed manner: they differentiated the target of blame and existing treatment measures between China and other countries or institutions but gave more exposure to China’s future obligations and duties. American and British media applied nearly identical coverage patterns in reporting China’s and others’ existing and future treatment but showed opposite patterns in covering the target of blame in environmental and climate issues. This article contributes to the study of China’s journalism practice in international communication. It also offers suggestions to the resolution of the stalemate in global environmental negotiations and China’s media ‘going global’ initiative.
Global Investors, the Dollar, and U.S. Credit Conditions

How does access to finance impact consumption volatility? Theory and evidence from advanced economies suggests that greater household access to finance smooths consumption. Evidence from emerging markets, where consumption is usually more volatile than income, indicates that financial reform further increases the volatility of consumption relative to output. This puzzle is addressed in the framework of an emerging economy model in which households face shocks to trend growth rate, and a fraction of them are financially constrained, with no access to financial services. Unconstrained households can respond to shocks to trend growth by raising current consumption more than the rise in current income. Financial reform increases the share of such households, leading to greater relative consumption volatility. Calibration of the model for pre- and post-financial reform in India provides support for the model’s key predictions.
An Optimal Symmetric Secret Distribution of Star Networks

Abstract : In this paper, we present a lower bound on secret distribution in star network. Examples of star communication network exist in various systems including sensor networks where there is one base station and several sensors that need to communicate with it. While the previous result had shown the possibility of performing secret distribution in a star network using 2 log n secrets, the lower bound for this problem was unknown. With this motivation, in this paper, we derive a tight bound for the number of secrets required for secret distribution in a star network. We show that as n, the number of satellite nodes in the star network, tends to infinity, it suffices to maintain log n + 1/2 log log n + 1 secrets at the center node. However, log n + 1/2 log log n secrets do not. Even in the absence of the constraint of n approaches infinity, we argue that these bounds are reasonably tight, i.e., there are several examples for finite values of n where [log n+1/2 log log n] secrets do not suffice although [log n + 1/2 log log n + 1] secrets suffice for virtually all cases of practical interest. We also show that our protocol could provide a tradeoff between internal and external attacks and to reduce the number of secrets in acyclic, planar and fully connected bipartite graphs.