Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring User Influence in Github: The Million Follower Fallacy

Influence in social networks has been extensively studied for collaborative-filtering recommendations and marketing purposes. We are interested in the notion of influence in Software Social Networks (SSNs); more specifically, we want to answer the following questions: 1) What does “influence” mean in SSNs? Given the variety of types of interactions supported in these networks and the abundance of centrality-type metrics, what is the nature of the influence captured by these matrics? 2) Are there silos of influence in these platforms or does influence span across thematic boundaries? To investigate these two questions, we first conducted an in-depth comparison of three influence metrics, number of followers, number of forked projects, and number of projectwatchers in GitHub1 (the largest code-sharing and version control system). Next, we examined how the influence of the most influential software-engineering people in GitHub is spread over different programming languages.Our results indicate (a) that the three influence metrics capture two major characteristics: popularity and content value (code reusability) and (b) that the influence of influentials is spread over more than one programming language, but there is no specific trend toward any two programming languages.
Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions.

BACKGROUND The monoclonal anti-CD20 antibody rituximab, combined with chemotherapeutic agents, has been shown to prolong overall survival in physically fit patients with previously untreated chronic lymphocytic leukemia (CLL) but not in those with coexisting conditions. We investigated the benefit of the type 2, glycoengineered antibody obinutuzumab (also known as GA101) as compared with that of rituximab, each combined with chlorambucil, in patients with previously untreated CLL and coexisting conditions. METHODS We randomly assigned 781 patients with previously untreated CLL and a score higher than 6 on the Cumulative Illness Rating Scale (CIRS) (range, 0 to 56, with higher scores indicating worse health status) or an estimated creatinine clearance of 30 to 69 ml per minute to receive chlorambucil, obinutuzumab plus chlorambucil, or rituximab plus chlorambucil. The primary end point was investigator-assessed progression-free survival. RESULTS The patients had a median age of 73 years, creatinine clearance of 62 ml per minute, and CIRS score of 8 at baseline. Treatment with obinutuzumab-chlorambucil or rituximab-chlorambucil, as compared with chlorambucil monotherapy, increased response rates and prolonged progression-free survival (median progression-free survival, 26.7 months with obinutuzumab-chlorambucil vs. 11.1 months with chlorambucil alone; hazard ratio for progression or death, 0.18; 95% confidence interval [CI], 0.13 to 0.24; P<0.001; and 16.3 months with rituximab-chlorambucil vs. 11.1 months with chlorambucil alone; hazard ratio, 0.44; 95% CI, 0.34 to 0.57; P<0.001). Treatment with obinutuzumab-chlorambucil, as compared with chlorambucil alone, prolonged overall survival (hazard ratio for death, 0.41; 95% CI, 0.23 to 0.74; P=0.002). Treatment with obinutuzumab-chlorambucil, as compared with rituximab-chlorambucil, resulted in prolongation of progression-free survival (hazard ratio, 0.39; 95% CI, 0.31 to 0.49; P<0.001) and higher rates of complete response (20.7% vs. 7.0%) and molecular response. Infusion-related reactions and neutropenia were more common with obinutuzumab-chlorambucil than with rituximab-chlorambucil, but the risk of infection was not increased. CONCLUSIONS Combining an anti-CD20 antibody with chemotherapy improved outcomes in patients with CLL and coexisting conditions. In this patient population, obinutuzumab was superior to rituximab when each was combined with chlorambucil. (Funded by F. Hoffmann-La Roche; ClinicalTrials.gov number, NCT01010061.).
Vision-Based Distributed Formation Control Without an External Positioning System

In this paper, we present a fully distributed solution to drive a team of robots to reach a desired formation in the absence of an external positioning system that localizes them. Our solution addresses two fundamental problems that appear in this context. First, we propose a 3-D distributed control law, designed at a kinematic level, that uses two simultaneous consensus controllers: one to control the relative orientations between robots, and another for the relative positions. The convergence to the desired configuration is shown by comparing the system with time-varying orientations against the equivalent approach with fixed orientations, showing that their difference vanishes as time goes to infinity. Second, in order to apply this controller to a group of aerial robots, we combine this idea with a novel sensor fusion algorithm to estimate the relative pose of the robots by using onboard cameras and information from the inertial measurement unit. The algorithm removes the influence of roll and pitch from the camera images and estimates the relative pose between robots by using a structure from the motion approach. Simulation results, as well as hardware experiments with a team of three quadrotors, demonstrate the effectiveness of the controller and the vision system working together.
Government Investment and Fiscal Stimulus in The Short and Long Runs

This paper contributes to the debate about fiscal multipliers by studying the impacts of government investment in conventional neoclassical growth models. The analysis focuses on two dimensions of fiscal policy that are critical for understanding the effects of government investment: implementation delays associated with building public capital projects and expected future fiscal adjustments to debt-financed spending. Implementation delays can produce small or even negative labor and output responses in the short run; anticipated fiscal financing adjustments matter both quantitatively and qualitatively for long-run growth effects. Taken together, these two dimensions have important implications for the short-run and long-run impacts of fiscal stimulus in the form of higher government infrastructure investment. The analysis is conducted in several models with features relevant for studying government spending, including utility-yielding government consumption, time-to-build for private investment, and government production.
ALL RESPONSES ARE NOT CREATED EQUAL

Abstract This exploratory study makes a contribution to the literature on antiracism by analyzing how first-generation French Blacks of sub-Saharan African descent practice everyday antiracism. In doing so, it expands the demographic terrain of this research to highlight some particularities in the experience of everyday racism and antiracism for ethnoracial minorities of immigrant origins. In addition to experiencing forms of racism encountered by both immigrants and other native ethnoracial minorities, first-generation French Blacks (like other non-White first-generation Europeans), face symbolic exclusion from the national community and delegitimization of their claims to Europeanness. Examining their experiences sheds light on how race, immigration, and national identity intersect to generate unique experiences of racism and antiracism. This paper also contributes to our understanding of how social context shapes the range of everyday antiracist strategies at a person's disposal. Specifically, integrating Kasinitz et al.'s (2008) framework for categorizing incidents of racial discrimination and prejudice with Fleming et al.'s (2010) categorization of responses to stigmatization, I present an analysis of antiracist responses that takes into account both the nature of the relationship between the victim and the perpetrator of racism (i.e., impersonal vs. personal) and the social context in which the encounter occurs (e.g., school, work, public space, etc). In doing so, I highlight how the conditions of a given incident of racism or discrimination set constraints on the range of antiracist responses an individual can practically (or feasibly) employ.
Effectiveness of clozapine, haloperidol and chlorpromazine in schizophrenia during a five-year period.

OBJECTIVE The aim of our study was to evaluate the effects of low doses of clozapine in flexible regime in comparison with haloperidol and chlorpromazine in long term. METHOD The naturalistic study was prospective, active-controlled with 325 adult outpatients of both genders (140 females), with mean year age of 34.8 (range 21-57), suffering from chronic schizophrenia. The first onset of illness was at the mean of 27.9 years (range 17-38), and subjects had the mean year age of 4.1+/-0.5 previous relapses. The patients were allocated to receive haloperidol (105 subjects, dose range 2-15 mg), chlorpromazine (n=105, 100-400 mg) or clozapine (n=115, 75-600 mg). The scores of psychometric instruments (GWB, PANSS, CGI) were regularly assessed during 5 year period. RESULTS The sixty-six responders were included in per-protocol analysis: 12, 10 and 16 with positive and 7, 6 and 15 with negative schizophrenic syndrome in haloperidol, chlorpromazine and clozapine group, respectively. The statistically significant differences in all psychometric scores was found, for both schizophrenic syndromes, favoring clozapine. The distribution of eighteen different types of adverse events, which we noted, were significantly different among treatment groups ( chi2=315.7, df=34, p<0.001). Clozapine was safer and had fewer adverse effects (average of 0.9 adverse events per patient) than haloperidol (2.7) and chlorpromazine (3.2). CONCLUSIONS Clozapine, in low doses of flexible regime, in long term (five years) showed better effectiveness in chronic schizophrenics with positive and negative symptoms than typical antipsychotics.
The relationship between self-efficacy, coping skill and substance use in adolescent: based on structural equation modeling

Abstract Background: This study was aimed to investigate interrelationships between the self-efficacy and coping skill in relation to substance use behavior in adolescent. Method: A self-administered questionnaire was completed by 720 girls and boys, aged between 14 and 18, involved in the cross-sectional study in Iran. In the first step, first-order measurement models were examined to assess how well the observed measures could reflect the latent constructs and in the second step, the structural component consisting of relationships between the latent factors was examined to determine the theoretical factors of the coping and self-efficacy predicted substance use behavior, as hypothesized. Result: The results of the first step revealed stable assessment of four confirmed factors in the first-order measurement model. In second step, the structural model of coping and self-efficacy showed an acceptable adequacy in predicting substance use behavior in the second-order model. Direct and indirect path analysis demonstrated that relationship between refusal self-efficacy and substance use would be mediated by the coping skill, and this relationship could significantly predict substance use behavior in our study. Conclusion: The results of our hypothesized model of coping self-efficacy (CSE) had an acceptable adequacy in predicting substance use behavior in adolescents.
Placental Changes in Gestational Diabetes: An Ultrastructural Study

A light microscopic, an electron microscopic, and a ultrahistochemical study have been made of seven placentas from women with mild and excellently controlled chemical gestational diabetes. Only one placenta showed no significant abnormality: the remainder showed, to a varying degree, changes in the syncytiotrophoblast, cytotrophoblast, trophoblastic basement membrane, and fetal vessels. These abnormalities were identical to and in some cases as se vere as those found in placentas from women with longstanding, moderately controlled, overt diabetes mellitus. These findings indicate that control of hyperglycemia only partially prevents the development of placental abnormalities which must be due to some other constituent factor of the diabetic state.
Different cortical projections from three subdivisions of the rat lateral posterior thalamic nucleus: a single‐neuron tracing study with viral vectors

The lateral posterior thalamic nucleus (LP) is one of the components of the extrageniculate pathway in the rat visual system, and is cytoarchitecturally divided into three subdivisions – lateral (LPl), rostromedial (LPrm), and caudomedial (LPcm) portions. To clarify the differences in the dendritic fields and axonal arborisations among the three subdivisions, we applied a single‐neuron labeling technique with viral vectors to LP neurons. The proximal dendrites of LPl neurons were more numerous than those of LPrm and LPcm neurons, and LPrm neurons tended to have wider dendritic fields than LPl neurons. We then analysed the axonal arborisations of LP neurons by reconstructing the axon fibers in the cortex. The LPl, LPrm and LPcm were different from one another in terms of the projection targets – the main target cortical regions of LPl and LPrm neurons were the secondary and primary visual areas, whereas those of LPcm neurons were the postrhinal and temporal association areas. Furthermore, the principal target cortical layers of LPl neurons in the visual areas were middle layers, but that of LPrm neurons was layer 1. This indicates that LPl and LPrm neurons can be categorised into the core and matrix types of thalamic neurons, respectively, in the visual areas. In addition, LPl neurons formed multiple axonal clusters within the visual areas, whereas the fibers of LPrm neurons were widely and diffusely distributed. It is therefore presumed that these two types of neurons play different roles in visual information processing by dual thalamocortical innervation of the visual areas.
Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.

BACKGROUND The genetic predisposition of the host to local or systemic inflammation may contribute to the effect of cancer cachexia. OBJECTIVE We investigated the relation between cytokine polymorphisms (IL1B -511, IL6 -174, IL10 -1082, TNFA -308, and LTA +252) and markers of nutritional status among patients with gastroesophageal cancer to determine whether any such association was reflected by cytokine concentrations in the tumor or plasma compartments. DESIGN Patients (n = 203) with a diagnosis of gastroesophageal cancer underwent nutritional assessment (body mass index, anthropometric measures, dysphagia scoring, and estimation of dietary intake). Single nucleotide polymorphism genotyping was performed by TaqMan allelic discrimination genotyping. Serum cytokine and C-reactive protein concentrations were determined by enzyme-linked immunosorbent assay. Tumor tissue cytokine protein concentrations (n = 56) were determined by using the Cytometric Bead Array System. RESULTS IL10 GG and IL6 CC polymorphisms were associated with elevated serum C-reactive protein concentrations, and the IL6 CC genotype was also associated with elevated tumor tissue cytokine concentrations. At diagnosis, the IL10 GG, but not the IL6, genotype was linked with increased total weight loss: 4.9% for AA, 7.1% for AG, and 12.0% for GG (P = 0.007). Serum C-reactive protein concentrations correlated with increased weight loss (r = 0.24, P < 0.001). Compared with other genotypes, the IL10 GG genotype retained an independent association in determining the extent of weight loss on multivariate analysis (95% CI: 0.52, 3.43; P = 0.008). Possession of the GG allele was associated with a 2.3 times increased risk of developing cachexia (95% CI: 1.2, 4.3; P = 0.014). CONCLUSION These data suggest that the IL10 genotype of the host can influence the development of cachexia among patients with gastroesophageal malignancy.
How to Explain the Parent's Cancer to their Children: A Specific Intervention to Enhance Communication Inside the Family

Objective: This article describes a multidisciplinary intervention dedicated to patients with cancer and with underage children. It is well known that children of severely ill parents can develop emotional and behavioral problems. Different studies underline the efficacy of an open communication with children about the parent’s illness to reduce distress but also the difficulties of parents to explain it to their children. The intervention, realized at San Gerardo Hospital, aims to inform or improve the children’s knowledge of their parent’s cancer, and to open communication about cancer inside the family. Methods: This intervention is characterized by the integration of a psychologist and a pediatric hematooncologist and by the direct involvement of children. After the fact-finding parents sessions, the pediatric hematooncologist and the psychologist meet children in specific settings, without parents present, to describe, with the support of images and metaphors, the parent’s cancer and to understand children’s needs or fears. In particular the pediatric hemato-oncologyst uses the flowered garden metaphor to explain to children the parent’s illness and the treatments. Then the clinicians share the content of the previous sessions with parents. Counseling sessions to parents are also organized to increase the parental competence and the sharing of cancer-related concerns in the family. In addition, a specific questionnaire has been realized to evaluate children’s psychological conditions after the intervention, family atmosphere and parents’ satisfaction. Results: 36 families and 53 children have participated in the project up to now. The results of the questionnaires have underlined the absence of psychopathological symptoms in children, the presence of more collaboration in the families and more possibilities in the family to have an open communication about the cancer. In addition, most of the parents reported a considerable satisfaction with the intervention. Conclusion: Support for open communication in the family about cancer should be acknowledged as an important aspect of oncology care to reduce family stress.
CYP17 promotor polymorphism and ovarian cancer risk

The CYP17 gene encodes the cytochrome P450c17α enzyme, which functions at 2 different points in the steroid biosynthesis pathway, and is considered a candidate susceptibility gene for endocrine‐related tumors. A T to C substitution polymorphism exists in the 5' promoter region of this gene, and creates an additional Sp1‐type motif. Several studies have examined this polymorphism as a risk factor for breast cancer, but results have been conflicting. We examined 319 cases of ovarian cancer and 298 unaffected controls for the T‐C polymorphism. There was no significant difference between cases and controls for the allele frequencies (p = 0.6), or for genotype distribution (p = 0.9). The odds ratio (95% confidence interval) for ovarian cancer was 1.13 (0.70–1.82) for the putative “cancer susceptibility” CC genotype and 1.07 (0.77–1.48) for any C allele (CC or CT genotype). Results were little different after adjustment for age. Stratification of the ovarian cancer cases according to form (benign, low malignant potential or invasive), histology, grade or stage failed to reveal any heterogeneity with respect to CYP17 genotype. Our data provide no evidence for an association between ovarian cancer risk and the genotype defined by the CYP17 5' promoter region T‐C polymorphism. Int. J. Cancer 86:436–439, 2000. © 2000 Wiley‐Liss, Inc.
The relationship between benefits of ERP systems implementation and its impacts on firm performance of SCM

Purpose – The purpose of this paper is to provide managers with a critical insight into the relationship between the benefits of enterprise resource planning (ERP) systems implementation and the impacts on firm performance of supply chain management (SCM). Design/methodology/approach – This study proposes a structural equation modeling (SEM) to analyze the relationship between ERP benefits and SCM performance. Hypotheses derived from the key benefits of adopting ERP system and related SCM practices presented by previous authors. An empirical survey is conducted to collect data from Taiwanese IT companies listed in the Taiwan Stock Exchanges on several aspects of firm competences and supply chain performance that adopted ERP systems and/or SCM systems.Findings – The results confirm the operational, tactical, and strategic benefits of ERP for the firm performance of SCM in the internal and external business processes, customer service, and cost management, except for the strategic benefits of ERP are not sig.
Restaurant employment boom in New York City

Editor,—On 10 April 1995, New York City (NYC) became the largest city in the USA to pass a smokefree restaurant law. This legislation prohibits smoking in the indoor dining area of restaurants with more than 35 seats. Smoking is still permitted in smaller restaurants, bar areas of restaurants, and stand alone bars and taverns. Opponents of the legislation argued that the law would cause significant adverse economic losses for restaurants. Even in 1995, there were convincing published data to suggest no adverse economic consequences.1 Since then, virtually all published studies have confirmed these findings,2-5 including a detailed economic evaluation of the …
Mentalisation-based therapy (MBT) in a high-secure hospital setting: expert by experience feedback on participation

Abstract Evidence for mentalisation-based therapy (MBT) is increasing in relation to the treatment of personality disorder. Individuals with personality disorder are over-represented in inpatient, forensic and forensic inpatient mental health services. This study explores MBT within a forensic setting as an intervention designed to moderate deficits linked to violence and to improve adaptive coping. Interpretative phenomenological analysis was conducted on interviews with four patients who completed MBT at a high-secure hospital. Findings suggest that MBT-enhanced participants’ mentalising which had a positive impact upon their capacity to manage their behaviour and emotions. MBT further enabled participants to process past experiences of violence and develop some degree of empathy for others, which led to a trend in abstinence from risk behaviours. Findings contribute a secure inpatient perspective on the experience of MBT and to MBT clinical outcomes.
DNA Barcodes and Targeted Sampling Methods Identify a New Species and Cryptic Patterns of Host Specialization Among North American Coptera (Hymenoptera: Diapriidae)

ABSTRACT Fewer than half of the 80–100 North American species in parasitoid genus Coptera Say (Hymenoptera: Diapriidae) have been described. Hosts are known for just nine of these. The taxonomy of Coptera has been complicated by its cryptic morphology and a life history that includes parasitism of pupae beneath the surface of soils. Here, we describe collections targeting the host genus with which Coptera have most frequently been associated: flies in genus Rhagoletis (Loew) (Diptera: Tephritidae). DNA barcodes, morphology, and ecology (host associations) were used to understand species limits for Coptera collected from Rhagoletis. Four species of Coptera were recovered from five species of Rhagoletis, including a new species: Coptera n. sp. 1. Two of the associations with particular species of Rhagoletis were previously unknown, and no two species of Coptera were found to be attacking the same host, suggesting these four Coptera are specialist parasites. As several of the 25 North American species of Rhagoletis are agricultural pests, a better understanding of their natural associations with Coptera may prove valuable to biological control efforts.