Miracle-dz/UniFAR-FTUs huggingface dataset:
Prior NLOS Measurement Correction for Positioning in Cellular Wireless Networks

A mobile station (MS) location can be estimated from the measurement of the time of arrival of the signals that travel between each base station and the MS. In this scenario, the existence of non-line-of-sight (NLOS) propagation paths has been considered to be the main drawback to achieve high precision in positioning, since NLOS propagation introduces large and unpredictable errors in the time estimates that are obtained from the measurements. In this paper, we propose a new technique, called prior NLOS measurement correction (PNMC), to effectively correct the measurements from NLOS propagation in a previous stage to the positioning process. PNMC is based on a statistical processing of a record of measurements taken over a time window. This processing relies on the statistical estimate of the NLOS measurement ratio present in our record. This estimate is used to range the NLOS recorded measurements into segments. Finally, the correction is carried out by subtracting the expected NLOS errors for each segment. Several simulations have been conducted to show the increase in accuracy obtained by the usage of PNMC and the great improvement that this prior measurement correction means to subsequent wireless location and positioning techniques.
Fetal hypoxic and ischemic injuries

Purpose of review The principles of neonatal neurological protection following intrapartum hypoxia are briefly reviewed. The physiological principles behind the use of cardiotocograph patterns in defining the timing and mechanism of fetal hypoxia and injury are then demonstrated. Recent findings Fetal neurological injury may result from progressive hypoxemia, acidosis, diminished cardiac output and cerebral ischemia, manifested at birth as low Apgar scores, multisystem compromise, severe acidosis and encephalopathy. More commonly, however, intrapartum injury results from often intermittent, regional ischemia secondary to umbilical cord or head compression resulting in hemorrhage or infarction. Under these circumstances, the amount of umbilical acidosis and neonatal encephalopathy varies and the potential candidate for neuroprotection may escape recognition and timely treatment. Selecting infants likely to benefit from neuroprotection requires information on the timing, duration and mechanism of hypoxia. Neonatal parameters, including low Apgar scores, acidosis, even seizures, lack sensitivity and specificity. Cardiotocograph patterns are capable of determining the duration, mechanism and severity of hypoxia and occasionally, the timing of neurological injury. Summary Protecting the newborn from the neurological consequences of intrapartum hypoxia requires critical definition of the mechanism and timing of this exposure. cardiotocograph tracings offer the opportunity to refine the selection of candidates for neonatal rescue.
Dose-Dependent Media Priming Effects of Stereotypic Newspaper Articles on Implicit and Explicit Stereotypes

Current research draws a distinction between stereotype activation and application. Building on this differentiation, we present an implicit social cognition model of media priming: Implicit stereotypes (i.e., automatically activated stereotypes) are the outcome of associative processes, whereas explicit stereotypes (i.e., overtly expressed judgments) represent the outcome of propositional processes. We tested some of the model's basic predictions in an experiment. We found that a Gaussian distribution function explained the explicit media priming effect (i.e., decay in effect size at very high dose levels). However, a monotonic function explained the implicit media priming effect. This indicates that stereotypic content may impact implicit stereotypes even if the mass-mediated content is perceived as invalid. We discuss this finding regarding possible media-based reduction strategies.
Metallicities and activities of southern stars

Aims. We present the results from high-resolution spectroscopic measurements to determine metallicities and activities of bright stars in the southern hemisphere. Methods. We measured the iron abundances ((Fe/H)'s) and chromospheric emission indices (loghRHK ) of 353 solar-type stars with V = 7.5−9.5. (Fe/H) abundances are determined using a custom χ 2 fitting procedure within a large grid of Kurucz model atmospheres. The chromospheric activities were determined by measuring the amount of emission in the cores of the strong Caii HK lines. Results. Our comparison of the metallicity sample to other (Fe/H) determinations was found to agree at the ±0.05 dex level for spectroscopic values and at the ±0.1 dex level for photometric values. The distribution of chromospheric activities is described by a bimodal distribution, agreeing with the conclusions from other works. Also an analysis of Maunder minimum status was attempted, and it was found that 6 ± 4 stars in the sample could be in a Maunder minimum phase of their evolution and hence the Sun should only spend a few per cent of its main sequence lifetime in Maunder minimum.
The Journal of Business-to-Business Marketing Comes of Age: Some Postscripts

ABSTRACT Every scholarly journal has a mandatory responsibility to carry out an internal, introspective meta-analysis of its intellectual stock and its emergent legacy, to take stock of where it has been and provide a blueprint for where it is headed. Most researchers will admit that such retrospective reviews are extremely important in a number of ways and mark a critical rite of passage for any journal. So when Journal of Business-to-Business Marketing (JBBM), the premier scholarly journal dedicated to the content area of business-to-business (B2B) field decided to develop such an article, it heralded its coming of age and joined the ranks of other scholarly marketing journals that similarly signaled their entry into sustainable mature phase of their life cycles by publishing such retrospectives. Unlike other retrospectives, however, the retrospective being published in this issue of JBBM is special in that it is coauthored by the journal's founding editor, David T. Wilson (1991–1995) and his successor and the current editor, J. David Lichtenthal (1995–current). In other words, between the two of them the review subsumes the entire institutional history and memory associated with the journal. And it shows. The objective of this commentary is to present some additional postscript tables associated with the content of the fourteen-year publishing history of JBBM to accompany the article by Lichtenthal, Mummalaneni, and Wilson (2008).
Abstract 628: Circulating Microparticles From Patients With Valvular Heart Disease and Cardiac Surgery Inhibit Endothelium Dependent Vasodilation.

Objective: Circulating microparticles (MPs) from some diseases play important roles on inflammation, coagulation and vascular injury. The vascular function is quite important for maintaining the circulation after cardiac surgery. However, the impact of MPs generated from valvular heart disease (VHD) and cardiac surgery on vascular function remains unknown. The present study is to investigate the impact of such MPs on vasodilation. Methods: MPs were isolated from age-match healthy subjects and patients with VHD before and at 12 h, 72 h after cardiac surgery. Effects of MPs on vasodilation of mice aorta, the phosphorylation and expression of Akt, protein kinase C βII (PKC-βII), p70S6K, endothelial nitric oxide synthase (eNOS) and caveolin-1, the association of eNOS with heat shock protein 90 (HSP90), generation of nitric oxide (NO) and superoxide anion (O2•–) of human umbilical vein endothelial cells (HUVECs) were determined. Results: Compared with MPs from healthy subjects, MPs from VHD patients before cardiac surgery can impair endothelium-dependent vasodilation, inhibit phosphorylation of Akt and eNOS, enhance expression of caveolin-1, and activation of PKC-βII, p70S6K, and reduced association of HSP90 with eNOS, decrease NO production and increase O2•– generation. Those effects were even stronger when treated with MPs from post- cardiac surgery. Conclusion: Our data demonstrated that circulating MPs generated before and after cardiac surgery in VHD patients contributed to endothelial dysfunction by inhibiting and uncoupling of eNOS activity. Circulating MPs may be a potential therapeutic target for maintenance of vascular function post-cardiac surgery.
Biomechanical Properties of Hip Cartilage in Experimental Animal Models

The material properties of normal adult articular cartilage were determined in the femoral head and acetabulum of baboons, dogs, and bovines, and were compared with those of normal human hip cartilage. In situ creep and recovery indentation experiments were performed using an automated creep indentation apparatus. To curvefit the entire creep curve, a numerical algorithm based on biphasic finite element methods and nonlinear optimization was developed. This effort represents the first successful use of 100% of the creep indentation curve to obtain the mechanical properties of normal articular cartilage. The results show that material properties of articular cartilage exhibit significant topographical variations in the femoral head and acetabulum, and between these two bone structures. Furthermore, significant differences exist in the mechanical properties of hip cartilage among the 4 species. Specifically, in all species the smallest aggregate modulus is found in the inferior aspect of the femoral head. Among all species, human hip cartilage is the stiffest in all test sites; bovine tissue is the softest. Human tissue has the smallest Poisson's ratio and permeability in all test sites. The aggregate modulus of human hip cartilage is closely resembled by that of baboon hip cartilage. Anatomically, canine and baboon hips exhibit similar characteristics to the human hip joint; the bovine hip joint is distinctly different. Based on this study's data, the baboon represents the most appropriate animal model of normal human hip articular cartilage.
No sex please, we're mitochondria: a hypothesis on the somatic unit of inheritance of mammalian mtDNA.

In this article we develop a model for the organization and maintenance of mitochondrial DNA (mtDNA) in mammalian somatic cells, based on the idea that the unit of genetic function comprises a group of mtDNA molecules that are semi-permanently associated as a mitochondrial nucleoid. Different mtDNA molecules within a nucleoid need not be genetically identical. We propose that nucleoids replicate faithfully via a kind of mitochondrial mitosis, generating daughter nucleoids that are identical copies of each other, but which can themselves segregate freely. This model can account for the very slow rates of mitotic segregation observed in cultured, heteroplasmic cell-lines, and also for the apparently poor complementation observed between different mutant mtDNAs co-introduced into rho(0) cells (cells that lack endogenous mtDNA). It also provides a potential system for maintaining the mitochondrial genetic fitness of stem cells in the face of a presumed high somatic mutation rate of mtDNA and many rounds of cell division in the absence of phenotypic selection. BioEssays 22:564-572, 2000.
Bisphenol A Release: Survey of the Composition of Dental Composite Resins

Background: Bisphenol A (BPA) is an endocrine disruptor with potential toxicity. Composite resins may not contain pure BPA, but its derivatives are widely used. Several studies found doses of BPA or its derivatives in saliva or urine of patients after composite resin placement. Objective: The aims of this study were to establish an exhaustive list of composite resins marketed in Europe and their composition, and to assess the extent of BPA derivatives used. Methods: A research on manufacturers' websites was performed to reference all composite resins marketed in Europe, then their composition was determined from both material safety data sheets and a standardized questionnaire sent to manufacturers. Manufacturers had to indicate whether their product contained the monomers listed, add other monomers if necessary, or indicate “not disclosed”. Results: 160 composite resins were identified from 31 manufacturers and 23 manufacturers (74.2%) responded to the survey. From the survey and websites, the composition of 130 composite resins (81.2%) was: 112 (86.2%) based on BPA derivatives, 97 (74.7%) on bis-GMA, 17 (13.1%) without monomer derived from BPA (UDMA, sometimes with TEGDMA) and 6 (4.6%) with UDMA (only); 1 (0.8%) did not contain a BPA derivative or UDMA or TEGDMA. Pure BPA was never reported. Conclusion: This work has established a list of 18 composite resins that contain no BPA derivative. Manufacturers should be required to report the exact composition of their products as it often remains unclear or incomplete.
Special needs in the twenty-first century: where we've been and where we're going

Alan Dyson, who last year gave the Gulliford lecture on which this article is based, takes a critical look at the relationship between ‘inclusion’ and ‘social inclusion’. He bases his analysis on a review of the history of special needs education and on some of the thinking which emerges from his work on a current research project, Understanding and developing inclusive practices in schools. This project is funded by ESRC (L 1392 51005) as part of the Teaching and Learning Research Programme and has been undertaken in collaboration with colleagues at Newcastle, Christchurch University College Canterbury and the University of Manchester. The later parts of this article refer to this project, although the views expressed are Alan Dyson's rather than those of the research team as a whole.
Regulation of calcium signaling in dendritic cells by 1,25‐dihydroxyvitamin D3

Dendritic cells (DCs) are antigen‐presenting cells that provide a link between innate and adaptive immunity. Ca2+‐dependent signaling plays a central regulatory role in DC responses to diverse antigens. DCs are a primary target of 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3], a secosteroid hormone, that, in addition to its wellestablished action on Ca2+ homeostasis, possesses immunomodulatory properties. Surprisingly, nothing is known about its effects on DC cytosolic Ca2+ activity. The present study explored whether 1,25(OH)2D3 modifies the intracellular Ca2+ concentration ([Ca2+]i) in DCs. Here we show that mouse DCs expressed K+‐independent (NCX1–3) and K+‐dependent (NCKX1, 3, 4, and 5) Na+/Ca2+ exchangers. Acute application of LPS (100 ng/ml) to DCs increased [Ca2+]i, an effect significantly blunted by prior incubation with 1,25(OH)2D3. 1,25(OH)2D3 increased the membrane abundance of the NCKX1 protein, up‐regulated the K+‐ and Na+‐dependent Ca2+ entry and enhanced the K+‐dependent Na+/Ca2+ exchanger currents. The NCKX blocker 3′,4′‐dichlorobenzamyl (DBZ) reversed the inhibitory effect of 1,25(OH)2D3 on the LPS‐induced increase of [Ca2+]i. Expression of the costimulatory molecule CD86 was down‐regulated by 1,25(OH)2D3, an effect reversed by DBZ. In summary, 1,25(OH)2D3 blunts the LPS‐induced increase in [Ca2+]i by stimulation of Na+/Ca2+ exchangerdependent Ca2+ extrusion, an effect that contributes to 1,25(OH)2D3‐mediated immunosuppression. The results disclose completely novel mechanisms in the regulation of DC maturation and function. —Shumilina, E. , Xuan, N. T. , Matzner, N. , Bhandaru, M. , Zemtsova, I. M. , Lang, F. Regulation of calcium signaling in dendritic cells by 1,25‐dihydroxyvitamin D3. FASEB J. 24, 1989–1996 (2010). www.fasebj. org
Prostate cancer and emotional functioning : Effects of mental adjustment, optimism, and appraisal

Abstract This study examined the interrelationships between mental adjustment to cancer (i.e., fighting spirit, helplessness, anxious preoccupation, and fatalism), optimism, appraisals (i.e., harm/loss, threat, and challenge), and emotional functioning (i.e., depression, anxiety, and self-esteem) in a small sample of men with prostate cancer. Various significant correlational findings were obtained, as hypothesized, and several of these results were supported further by conservative hierarchical multiple regression analyses. Specifically, these latter analyses revealed that increased helplessness was related to decreased self-esteem and that increased anxious preoccupation was related to increased depression. Loss appraisals were related to increased depression and threat appraisals were related to increased anxiety. Finally, optimism was negatively related to increases in both depression and anxiety. The findings are discussed within the framework of previous research and the relevance of psychosocial va.
Boot Camp and Inmate Moral Development

This article reports on Project CORE (Convicted Offender Re-entry Effort), a boot camp program undertaken by the Travis County (Texas) Sheriff's Department. Though it had been anticipated that a boot camp program, with strong emphasis on responsibility and moral development, would yield increasing maturation in moral judgment, no significant increases were found.
Self-Compassion and Interpersonal Cognitive Distortions

Bu arastirmanin amaci oz-duyarlik ile iliskilerle ilgili bilissel carpitmalar arasindaki iliskileri incelemektir.Arastirmanin orneklemini 338 universite ogrencisi olusturmaktadir. Katilimcilara Oz-duyarlik Olcegi ve Iliskilerle IlgiliBilissel Carpitmalar Olcegi uygulanmistir. Oz-duyarlik ile iliskilerle ilgili bilissel carpitmalar arasindaki iliskileri incelemekicin yapilan korelasyon sonucunda oz-duyarligin, oz-sevecenlik, paylasimlarin bilincinde olma ve bilinclilik alt boyutlarininiliskilerle ilgili bilissel carpitmalarla negatif, oz-yargilama, izolasyon ve asiri ozdeslesme boyutlarinin ise pozitif iliskilioldugu gorulmustur. Iliskilerle ilgili bilissel carpitmalarin oz-duyarlik tarafindan aciklanma duzeyini belirlemek amaciylakurulan yapisal esitlik modelinden elde edilen uyum indeksleri modelin iyi uyum verdigini gostermistir (χ2/sd= 1.37, p=.036,GFI=.97, AGFI=.94, CFI=.99, NFI=.98, IFI=.99, RFI=.96, SRMR=.036 ve RMSEA=.040). Oz-duyarligin iliskilerle ilgilibilissel carpitmalari aciklama orani R2=. 93 olarak bulunmustur. Path analizi sonuclari, oz-duyarligin oz-sevecenlik,paylasimlarin bilincinde olma ve bilinclilik boyutlarinin iliskilerle ilgili bilissel carpitmalari negatif, oz-yargilama, izolasyonve asiri ozdeslesme boyutlarinin ise pozitif yonde yordadigini ortaya koymustur. Bulgular literatur isiginda tartisilmistir
Asymmetric Perception of Gains vs Non-Losses and Losses vs Non-Gains: The Causal Role of Regulatory Focus

Recent studies show that, while losses loom larger than equivalent non-gains, gains loom larger than equivalent non-losses. This finding, at odds with the loss aversion principle, has been interpreted within the framework of regulatory focus theory. In this study, we explore the causal effect of regulatory focus on the asymmetric perception of gains vs non-losses and losses vs non-gains. We examine the perceived effects of both hypothetical and actual changes in monetary wealth, while orthogonally manipulating framing, valence, and regulatory focus. We find a significant interaction between the three factors. The gain vs non-loss asymmetry in perceived satisfaction is stronger in promotion focus, while the loss vs non-gain asymmetry in perceived dissatisfaction is stronger in prevention focus. The results suggest that the effects of incentives framed in terms of (non)gains and (non)losses, depend on their congruence with the individual’s motivational state.
Automatic test pattern generation for resistive bridging faults

An ATPG for resistive bridging faults is proposed that combines the advantages of section-based generation and interval-based simulation. In contrast to the solutions introduced so far, it can handle arbitrary non-feedback bridges between two nodes, including ones detectable at higher resistance and undetectable at lower resistance, and faults requiring more than one vector for detection.
Atmospheric Chemistry and Physics Global Modelling of Secondary Organic Aerosol in the Troposphere: a Sensitivity Analysis

A global 3-dimensional chemistry/transport model able to describe O 3 , NO x , Volatile Organic Compounds (VOC), sulphur and NH 3 chemistry has been extended to simulate the temporal and spatial distribution of primary and secondary carbonaceous aerosols in the tropo-sphere focusing on Secondary Organic Aerosol (SOA) formation. A number of global simulations have been performed to determine a possible range of annual global SOA production and investigate uncertainties associated with the model results. The studied uncertainties in the SOA budget have been evaluated to be in decreasing importance: the potentially irreversible sticking of the semi-volatile compounds on aerosols, the enthalpy of vaporization of these compounds, the partitioning of SOA on non-carbonaceous aerosols, the conversion of aerosols from hydrophobic to hy-drophilic, the emissions of primary carbonaceous aerosols, the chemical fate of the first generation products and finally the activity coefficient of the condensable species. The large uncertainties associated with the emissions of VOC and the adopted simplification of chemistry have not been investigated in this study. Although not all sources of uncertainties have been investigated, according to our calculations, the above factors within the experimental range of variations could result to an overall uncertainty of about a factor of 20 in the global SOA budget. The global annual SOA production from biogenic VOC might range from 2.5 to 44.5 Tg of organic matter per year, whereas that from anthropogenic VOC ranges from 0.05 to 2.62 Tg of organic matter per year. These estimates can be considered as a lower limit, since partitioning on coarse particles like nitrate, dust or sea-salt, together with the partitioning and the dissociation of the semi-volatile products in aerosol water has been neglected. Comparison of model results to observations, where available, shows a better agreement for the upper budget estimates than for the lower ones.
Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development

Specificity protein (Sp) transcription factors (TFs) such as Sp1 are critical for early development but their expression decreases with age and there is evidence that transformation of normal cells to cancer cells is associated with upregulation of Sp1, Sp3, and Sp4, which are highly expressed in cancer cells and tumors. Sp1 is a negative prognostic factor for pancreatic, colon, glioma, gastric, breast, prostate, and lung cancer patients. Functional studies also demonstrate that Sp TFs regulate genes responsible for cancer cell growth, survival, migration/invasion, inflammation and drug resistance, and Sp1, Sp3 and Sp4 are also nononcogene addiction (NOA) genes and important drug targets. The mechanisms of drug-induced downregulation of Sp TFs and pro-oncogenic Sp-regulated genes are complex and include ROS-dependent epigenetic pathways that initially decrease expression of the oncogene cMyc. Many compounds such as curcumin, aspirin, and metformin that are active in cancer prevention also exhibit chemotherapeutic activity and these compounds downregulate Sp TFs in cancer cell lines and tumors. The effects of these compounds on downregulation of Sp TFs in normal cells and the contribution of this response to their chemopreventive activity have not yet been determined. Cancer Prev Res; 11(7); 371–82. ©2018 AACR.