Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGEMBANGAN PERANGKAT PEMBELAJARAN IPA TERPADU DENGAN SETTING INKUIRI TERBIMBING UNTUK MENINGKATKAN PEMAHAMAN KONSEP DAN KINERJA ILMIAH SISWA

Abstrak Sesuai dengan tuntutan kurikulum KTSP pembelajaran IPA di SMP dilaksanakan secara terpadu, namun kenyataannya pembelajaran IPA masih dilakukan secara parsial. Oleh karena itu, peneliti ingin mengakomodasi dengan membuat perangkat pembelajaran IPA terpadu. Tujuan dari penelitian ini adalah menghasilkan perangkat pembelajaran IPA terpadu dengan setting inkuiri terbimbing yang valid, praktis, dan efektif. Perangkat pembelajaran yang dikembangkan meliputi buku siswa dan buku pegangan guru. Metode penelitian dilakukan dengan analisis deskriptif tentang validitas, kepraktisan, dan efektivitas perangkat pembelajaran. Dari hasil penelitian diperoleh: 1) validitas perangkat pembelajaran berada pada kategori sangat valid dengan nilai validitas buku siswa 3,57 dan buku pegangan guru 3,63, 2) kepraktisan perangkat pembelajaran berada pada kategori sangat praktis, dengan nilai keterlaksanaan perangkat pembelajaran pada kategori praktis dan sangat praktis, rata-rata nilai respon guru 3,87 dan respon siswa 3,66, 3) keefektivan perangkat, nilai rata-rata pemahaman konsep 85,16 dan kinerja ilmiah yang berupa penilaian unjuk kerja dan sikap berada diatas KKM, sehingga dinyatakan 100% tuntas. Hal ini berarti, perangkat pembelajaran memenuhi kriteria valid, praktis, dan efisien sehingga dapat diimplementasikan dalam lingkup yang luas. Kata Kunci : Perangkat pembelajaran, IPA Terpadu, Pemahaman Konsep, Kinerja Ilmiah Abstract In accordance with the demands of the curiculum in Junior High School integrated science implemented in an integrated manner, but the fact that learning science is done partially. Therefore, the researchers wanted to accommodate by making integrated science teaching tools. The purpose of this research is to produce devices with integrated science teaching guided inquiry setting valid, practical, and effective. Developed learning tools include student books and teacher handbooks. Research methods with descriptive analysis of the validity, practicality, and effectiveness of the learning. The results were obtained: 1) the validity of the study were very valid in the category with the validity of the book value of 3.57 and the student teacher handbook 3.63, 2) the practicality of the device is in the category of learning is very practical, with the value of the feasibility study on the practical category and very practical, the average value of the response of teachers and students' responses 3.66 and 3.87, 3) the effectiveness of the device, the average value of 85.16 and understanding of the concept of scientific performance appraisal form performance is above KKM and attitudes, so stated 100% complete. This means, the study met the criteria valid, practical, and efficient so that it can be implemented in a broad scope. Keywords : Learning device, Integrated Science, Understanding Concepts, Performance Scientific
Oral reading fluency and comprehension in Kenya: reading acquisition in a multilingual environment

Reading research has shown that variable relationships exist between measures of oral reading fluency and reading comprehension, depending on whether the language of the text is the reader's first language or an additional language. This paper explores this phenomenon, using reading assessment data for 2,000 Kenyan children in two or three languages: English, Kiswahili and one of two mother tongues, Dholuo or Gikuyu. The assessment data allowed us to compare reading and comprehension rates across languages. The data indicated that many children could read English words more easily than words in Kiswahili or their mother tongue; nevertheless, their reading comprehension was significantly lower in English than in Kiswahili, Dholuo or Gikuyu. The paper concludes that emphasising English reading fluency is an inefficient route to gaining reading comprehension skills because pupils are actually attaining minimal oral reading fluency in English and only modest comprehension skills in their own languages. The evidence also demonstrates that Kenya's national language policy of mother tongue as a medium of instruction in the early primary grades is consistently ignored in practice.
CONTEMPORARY VIEWPOINTS ON TRANSPERSONAL PSYCHOLOGY

Over the past 35 years the published scholarly conversation about the nature of transpersonal psychology has continued as an ongoing and open-ended forum that reflects a continued vitality within the field. This article presents 41 contemporary viewpoints on transpersonal psychology, solicited from international scholars and new voices as well as from leading theorists and practitioners. These responses represent a sizeable spectrum of perspectives, and offer a framework around which the reader is invited to contemplate both foundational themes and shifting emphases within transpersonal psychology. The diversity of views is offered as a document to reflect the contemporary conversation about the field, as a stimulus for further dialogue and critical reflection, and as a support for innovative and emerging perspectives within transpersonal psychology. As interest in the field of transpersonal psychology continues to expand, it is critical to maintain an active exploration of principal viewpoints and nascent themes. The purpose of this forum is to present contemporary viewpoints on transpersonal psychology as an invitation for further discussion. This offers an opportunity for those within the field to continually reflect upon and reexamine their perspectives, and for those new to transpersonal psychology to engage in a living examination of the foundation and development of the field.
Athletic trainers' attitudes and judgments of injured athletes' rehabilitation adherence.

Abstract Certified athletic trainers (ATCs) in District 2 (n=187) of the National Athletic Trainers' Association (NATA) were asked to complete a questionnaire that assessed the attitudes and judgments of ATCs concerning numerous factors presumed to influence sport injury rehabilitation. Gender and experience differences in ATCs' attitudes and judgments about rehabilitation adherence were examined. Successful and unsuccessful adherence strategies also were reported. The questionnaire consisted of 60 statements that were categorized into seven scales: athletic trainer's influence, environmental influences, athlete's personality, pain tolerance, selfmotivation, goals and incentives, and significant others. There were no significant differences for either gender or experience of ATCs on any of the seven scales. An analysis of questionnaire item responses revealed the following as factors ATCs deemed important to injury rehabilitation: a) good rapport and communication between the ATC and the injured athlete, b) explanation of the injury and rehabilitation regimen, c) convenience and accessibility of the rehabilitation facility, d) rehabilitation sessions planned around the athletes' busy schedules, e) athletes' beliefs that the program is worth pursuing, f) personal supervision and regular monitoring, g) need for injured athletes to see immediate results, and h) support from significant others. ATCs reported education, goal setting, encouragement, monitoring progress, and support systems as successful strategies. Threats and rehabilitation without monitoring were reported as unsuccessful strategies.
Motivación en las clases de educación física : un estudio de la perspectiva de las metas de logro en el contexto educativo

Este estudio examino las relaciones entre las orientaciones de meta, el clima motivacional percibido, la percepcion de habilidad, la preferencia por tareas con diferente grado de dificultad, la satisfaccion, la diversion, la preferencia por distintos tipos de evaluacion y la valoracion que los estudiantes hacian de las clases de educacion fisica. 280 estudiantes respondieron a una serie de cuestionarios para analizar las variables mencionadas. Los resultados mostraron, de forma general, que la orientacion a la tarea, la percepcion de habilidad y la percepcion de un clima motivacional orientados a la tarea eranbuenos predictores de la preferencia por tareas desafiantes, la satisfaccion con experiencias de maestria, la diversion, la preferencia por contenidos evaluativos relativos al progreso personal y una alta valoracion de la educacion fisica. Por el contrario la orientacion al ego, la percepcion de habilidad y la percepcion deun clima motivacional orientado al ego, aparecieron como predictores de la preferencia por tareas faciles, la satisfaccion con el exito normativo, el aburrimiento, la preferencia por la evaluacion del rendimiento comparativo y una menor valoracion de la educacion fisica.
The Strengths Model: A Recovery-Oriented Approach to Mental Health Services

Foreword, Patricia Deegan Preface 1. History, Critique, and Useful Conceptions: Toward a Strengths Paradigm 2. A Beginning Theory of Strengths 3. The Purpose, Principles, and Research Results of the Strengths Model 4. Engagement and Relationship: A New Partnership 5. Strengths Assessment: Amplifying the Well Part of the Individual 6. Personal Planning: Creating the Achievement Agenda 7. Resource Acquisition: Putting Community Back into Community Mental Health 8. Supportive Case Management Context: Creating the Conditions for Effectiveness 9. Strengths Model Epilogue: Commonly Asked Questions (Objections) Appendix I. Spirit-Breaking Behaviors Appendix II. Hope-Inducing Behaviors Appendix III. Areas to Explore Through the Strengths Assessment Appendix IV. Quality Review of Strengths Assessment Appendix V. Strengths Model Core Competencies Evaluation Tool Appendix VI. Strengths Model Case Management Fidelity Scale References Index
Molecular Characterization of the Complete Genome of Three Basal-BR Isolates of Turnip mosaic virus Infecting Raphanus sativus in China

Turnip mosaic virus (TuMV) infects crops of plant species in the family Brassicaceae worldwide. TuMV isolates were clustered to five lineages corresponding to basal-B, basal-BR, Asian-BR, world-B and OMs. Here, we determined the complete genome sequences of three TuMV basal-BR isolates infecting radish from Shandong and Jilin Provinces in China. Their genomes were all composed of 9833 nucleotides, excluding the 3′-terminal poly(A) tail. They contained two open reading frames (ORFs), with the large one encoding a polyprotein of 3164 amino acids and the small overlapping ORF encoding a PIPO protein of 61 amino acids, which contained the typically conserved motifs found in members of the genus Potyvirus. In pairwise comparison with 30 other TuMV genome sequences, these three isolates shared their highest identities with isolates from Eurasian countries (Germany, Italy, Turkey and China). Recombination analysis showed that the three isolates in this study had no “clear” recombination. The analyses of conserved amino acids changed between groups showed that the codons in the TuMV out group (OGp) and OMs group were the same at three codon sites (852, 1006, 1548), and the other TuMV groups (basal-B, basal-BR, Asian-BR, world-B) were different. This pattern suggests that the codon in the OMs progenitor did not change but that in the other TuMV groups the progenitor sequence did change at divergence. Genetic diversity analyses indicate that the PIPO gene was under the highest selection pressure and the selection pressure on P3N-PIPO and P3 was almost the same. It suggests that most of the selection pressure on P3 was probably imposed through P3N-PIPO.
Human Ninein is a Centrosomal Autoantigen Recognized by CREST Patient Sera and Plays a Regulatory Role in Microtubule Nucleation

Centrosome is the major microtubule organizing center in mammalian cells that plays a critical role in a variety of cellular events by the microtubule arrays emanating from it. Despite its significance, the molecular mechanisms underlying the structure and function of the centrosome are still not clear. Herein we describe the identification of three isotypes of human ninein by expression library screening with autoimmune sera from CREST patients. All three ninein isotypes exhibit centrosomal localization throughout the cell cycle when GFP-tagged fusion proteins are expressed transiently in mammalian cells. Construction of serial deletions of GFP-tagged ninein reveals that a stretch of three leucine zippers with a flanking sequence is required and sufficient for centrosomal targeting. Overexpression of ninein results in mislocalization of ? -tubulin, recruiting it to ectopic (non-centrosomal) ninein-containing sites which are not active in nucleating microtubules. In these cells, nucleation of microtubules from the centrosome is also inhibited. These results thus suggest a regulatory role for ninein in microtubule nucleation.
Agrobacterium tumefaciens VirB9, an Outer-Membrane-Associated Component of a Type IV Secretion System, Regulates Substrate Selection and T-Pilus Biogenesis

ABSTRACT Agrobacterium tumefaciens translocates DNA and protein substrates between cells via a type IV secretion system (T4SS) whose channel subunits include the VirD4 coupling protein, VirB11 ATPase, VirB6, VirB8, VirB2, and VirB9. In this study, we used linker insertion mutagenesis to characterize the contribution of the outer-membrane-associated VirB9 to assembly and function of the VirB/D4 T4SS. Twenty-five dipeptide insertion mutations were classified as permissive for intercellular substrate transfer (Tra+), completely transfer defective (Tra−), or substrate discriminating, e.g., selectively permissive for transfer only of the oncogenic transfer DNA and the VirE2 protein substrates or of a mobilizable IncQ plasmid substrate. Mutations inhibiting transfer of DNA substrates did not affect formation of close contacts of the substrate with inner membrane channel subunits but blocked formation of contacts with the VirB2 and VirB9 channel subunits, which is indicative of a defect in assembly or function of the distal portion of the secretion channel. Several mutations in the N- and C-terminal regions disrupted VirB9 complex formation with the outer-membrane-associated lipoprotein VirB7 or the inner membrane energy sensor VirB10. Several VirB9.i2-producing Tra+ strains failed to elaborate T pilus at detectable levels (Pil−), and three such Tra+ Pil− mutant strains were rendered Tra− upon deletion of virB2, indicating that the cellular form of pilin protein is essential for substrate translocation. Our findings, together with computer-based analyses, support a model in which distinct domains of VirB9 contribute to substrate selection and translocation, establishment of channel subunit contacts, and T-pilus biogenesis.
Mitbestimmung für die Europäische Aktiengesellschaft: Nützliche Lehren aus mehr als dreißig Jahren Seifenoper

Dreisig Jahre lang haben Instanzen der EU (fruher: EWG = Europaische Wirtschaftsgemeinschaft, dann EG = Europaische Gemeinschaften) Entwurfe eines Statuts fur eine Europaische Aktiengesellschaft (SE), bestimmt fur multinationale Unternehmen, behandelt, bevor eine neue Form des Status 2001 Rechtskraft erlangte. Besonders kontrovers waren an dem jeweiligen Statutentwurf die Regelungen zur Mitbestimmung. Langfristig zeigte sich eine zunehmende Tendenz zur Renationalisierung der Regulierung von Mitbestimmung, und zu allein rudimentaren materialen Beteiligungsrechten. Dabei spielten allgemeine Renationalisierungstendenzen und der internationale Aufschwung der Arbeitsbeziehungen nach anglo-amerikanischem statt rheinischem Muster eine wichtige Rolle. Es zeigte sich aber auch, dass unpolitische Sozialforschung einen guten Teil der muhsam gefundenen Losung vorweg nehmen oder vorhersagen konnte: Die unternehmensspezifische Ausgestaltung der Europaischen Betriebsrate im Anschluss an nationale Organe, unter Verzicht auf Urwahl, hatte der Verfasser bereits im Abschluss einer vergleichenden Untersuchung 1974 mit vorgeschlagen. Die Geschichte des Statuts scheint exemplarisch zu zeigen, dass europaische Integration, wie nationale auch, uber weite Strecken paradox verlauft.
Comprehensive analysis of small RNA-seq data reveals that combination of miRNA with its isomiRs increase the accuracy of target prediction in Arabidopsis thaliana

Along with the canonical miRNA, distinct miRNA-like sequences called sibling miRNAs (sib-miRs) are generated from the same pre-miRNA. Among them, isomeric sequences featuring slight variations at the terminals, relative to the canonical miRNA, constitute a pool of isomeric sibling miRNAs (isomiRs). Despite the high prevalence of isomiRs in eukaryotes, their features and relevance remain elusive. In this study, we performed a comprehensive analysis of mature precursor miRNA (pre-miRNA) sequences from Arabidopsis to understand their features and regulatory targets. The influence of isomiR terminal heterogeneity in target binding was examined comprehensively. Our comprehensive analyses suggested a novel computational strategy that utilizes miRNA and its isomiRs to enhance the accuracy of their regulatory target prediction in Arabidopsis. A few targets are shared by several members of isomiRs; however, this phenomenon was not typical. Gene Ontology (GO) enrichment analysis showed that commonly targeted mRNAs were enriched for certain GO terms. Moreover, comparison of these commonly targeted genes with validated targets from published data demonstrated that the validated targets are bound by most isomiRs and not only the canonical miRNA. Furthermore, the biological role of isomiRs in target cleavage was supported by degradome data. Incorporating this finding, we predicted potential target genes of several miRNAs and confirmed them by experimental assays. This study proposes a novel strategy to improve the accuracy of predicting miRNA targets through combined use of miRNA with its isomiRs.
Comparing apples to apples: a qualitative investigation of career mobility patterns across four generations

Purpose – This study aims to compare the career patterns of Matures, Baby Boomers, Generation Xers and Millennials over the various stages of their careers to determine whether there have been notable shifts away from the “traditional” career model characterized by long‐term linear, upward career movement, toward a “modern” career model characterized by increased job mobility, organizational mobility and multi‐directional career movement.Design/methodology/approach – The retrospective career accounts of 105 Canadians were gathered through review of resume information and semi‐structured interviews. The job changes and organizational changes experienced by each respondent in each five‐year career period (e.g. age 20‐24, 25‐29) and the direction of job changes (i.e. upward, downward, lateral or change of career track) were recorded. The generations were compared statistically on each of these measures through analysis of variance (ANOVA). Findings – Significant inter‐generational differences were observed on.
Understanding teachers' concurrent knowledge of assessment literacy and curriculum-based measurement

As a result of the standards-based movement in education it is important for teachers to be knowledgeable about and understand the use of assessment in the general education setting. Prior studies have investigated teachers’ understanding of sound assessment known as assessment literacy. This study explores teachers’ concurrent knowledge of Curriculum-Based Measurement and sound assessment, as measured by the Assessment Literacy Inventory. More specifically, the extent of the relationship is examined by the Pearson product-moment correlation coefficient. Additionally, the relationship between training and knowledge about CBM is described. Results of the current study revealed a moderate, positive relationship between scores on measures of knowledge about CBM and assessment literacy. It is unclear if training is related to knowledge about CBM or assessment literacy. Implications of these results and the conceptualization of assessment literacy, as well as limitations of the study, are discussed.
Hypercontractile esophagus: Clinical context and motors findings in high resolution manometry.

BACKGROUND Hypercontractile esophagus (HE) is a primary hypercontractile disorder of the esophageal musculature not frequently seen in the general population. It is characterized by the presence of at least one contraction with a very high amplitude and duration (DCI > 8,000 mmHg/s/cm) in patients with esophageal symptoms. The aim of our study was to assess the clinical context and manometric characteristics in patients with HE using highresolution manometry (HRM). METHODS We thoroughly reviewed the clinical features and manometric findings of a total of 720 patients with esophageal symptoms that were attended in the Department of Gastroenterology of our hospital between June 2011 and June 2013. RESULTS We found seven patients that met criteria for HE according to the Chicago Classification (2012). All of the patients were women (100%). Mean age was 64 years old. Most frequent symptoms were: Chest pain, dysphagia and heartburn.In one patient (14%) the HE was related to a gastroesophageal reflux disease (GERD) and gastroesophageal junction (GEJ) outflow obstruction. Three patients (43%) had more than one hypercontractile contraction in the study. Four patient (57%) hade multipeaked pattern (Jackhammer esophagus) and y two of them were synchronized with respiration. Two patients (29%) were diagnosed with hiatus hernias. Integrated relaxation pressure (IRP) was not higher in hypercontractile contractions than in normal contractions. Only one patient presented a slight alteration of the relaxation (IRP-4s = 15 mmHg) with normal peristalsis, GEJ outflow obstruction and not multipeakeded pattern. One patient presented pathological acid exposure (PAE) in 24-hours pH-metry. CONCLUSIONS HE is a rare disorder and HRM is essential for its correct diagnosis and characterization. The treatment of HE should achieve the disappearance or at least improvement of the patient´s symptoms and avoid unnecessary diagnostic testing.
Transcription of the Staphylococcus aureus cid and lrg Murein Hydrolase Regulators Is Affected by Sigma Factor B

ABSTRACT The Staphylococcus aureus lrg and cid loci are homologous operons that have been shown to regulate murein hydrolase activity and affect sensitivity to penicillin. Although the mode of action of these operons has not been demonstrated, a model based on the similarities of the lrgA and cidA gene products to the bacteriophage holin family of proteins has been proposed. In this study, the transcription organization and regulation of these operons were examined by Northern blot analyses. Unexpectedly, cidB and a gene located immediately downstream, designated cidC, were found to be cotranscribed on a 2.7-kb transcript. Maximal cidBC transcription occurred during early exponential growth, and high-level transcription of cidBC was dependent on the rsbU-mediated activation of the alternative sigma factor B (σB). In contrast, lrgAB transcription in stationary phase was negatively regulated by σB. Although cidABC transcription was not detected by Northern blot analysis, reverse transcriptase PCR revealed that these genes are also cotranscribed as a single RNA message in early exponential growth. Primer extension analysis revealed the presence of two cidBC transcription start sites, but no apparent σB-dependent promoter consensus sequence was identified in these regions. The rsbU gene was also shown to have a positive impact on murein hydrolase activity but a negligible effect on sensitivity to penicillin-induced killing. These results suggest that the lrgAB and cidBC genes may be part of the S. aureus σB-controlled stress regulon.