Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing a package for analysis and design optimization of wind turbine systems

The installation of wind turbines and consequently the use of wind energy is increasing day by day, since the rapid development in semiconductor technology has led to more advance in the wind turbine technologies. On the other hand, it is well known that a Graphical User Interface (GUI) application provides great advantages to the user such as; the use of programming language and data input for systems without coding, getting the results with the help of symbols, icons and other visual graphics. Accordingly, in this paper, to determine the amount of energy production, cost of energy and etc., of a Wind Turbine System (WTS) that has been established or will be installed, a tool is introduced by the presented software package. Besides the analysis option, the package also offers optimization algorithms that would be used for the layout design of types of Wind Turbine Systems which are called fixed-speed and variable-speed Wind Turbine Systems seperately by keeping in consideration the wind speed and geographic features of the regions. The graphical user interface, which is the one of important features of C# program were used and called Analysis & Design Optimization Package (A&DOP).
Law, Finance, and Economic Growth in China

China is an important counterexample to the findings in the law, institutions, finance, and growth literature: Neither its legal nor financial system is well developed, yet it has one of the fastest growing economies. While the law–finance–growth nexus applies to the State Sector and the Listed Sector, with arguably poorer applicable legal and financial mechanisms, the Private Sector grows much faster than the others and provides most of the economy’s growth. The imbalance among the three sectors suggests that alternative financing channels and ARTICLE IN PRESS
A Step Towards Detecting Online Grooming -- Identifying Adults Pretending to be Children

Online grooming is a major problem in todays society where more and more time is spent online. To become friends and establish a relationship with their young victims in online communities, groomers often pretend to be children. In this paper we describe an approach that can be used to detect if an adult is pretending to be a child in a chat room conversation. The approach involves a two step process wherein authors are first classified as being children or adults, and then each child is being examined and false children distinguished from genuine children. Our results show that even if it is hard to separate ordinary adults from children in chat logs it is possible to distinguish real children from adults pretending to be children with a high accuracy. In this paper we will discuss the accuracy of the methods proposed, as well as the features that were important in their success. We believe that this work is an important step towards automated analysis of chat room conversation to detect and possible attempts of grooming. Our approach where we use text analysis to distinguish adults who are pretending to be children from actual children could be used to inform children about the true age of the person that they are communicating. This would be a step towards making the Internet more secure for young children and eliminate grooming.
Capital Accumulation and Habits

This paper investigates the impact of habits on savings and steady state capital intensity. Within the framework of an OLG economy with productive capital, a rise in the strength of habits increases savings if the steady state is asymptotically stable. Consequently, the steady state capital intensity as implied by an OLG model with habits is higher compared to the case with time-separable utility. If, however the initial steady state is unstable, a rise in the strength of habits lowers savings.
Students’ Problem Solving Appraisal and Behaviour in Asynchronous Online Discussion Forum

This study is intended to identify student problem-solving appraisal and their problem-solving behaviour in asynchronous online discussion forums (AODF). Thirty students enrolled in Authoring Language (AL) participated in this study. This study intends to explore the relationship between students’ problem-solving appraisal in AODF with their actual AODF behaviour, and to determine whether there is any correlation between their academic performance of AL course. This study involved quantitative and qualitative data collection. Problem Solving Inventory (PSI) and students’ AODF transcripts were used as research instruments. Also, students’ performance scores of the AL course were gathered as part of the data for this research. The findings have revealed that a high PSI score reflects positive problem-solving skills, with an average PSI score being 97.43. The most dominant problem-solving behaviour in AODF is ‘providing information’ behaviour. Students’ problem-solving behaviour in AODF has been decreasing across time, and there is a moderately significant correlation between the PSI score and total marks for the AL course (r=0.449, p<0.05). The findings of this study may provide instructors with detailed information about students’ problem-solving appraisal and problem-solving behaviour in AODF and their impact on students’ academic performance.
Catalytic Domain of Phosphoinositide-specific Phospholipase C (PLC)

Structural studies of phospholipase C δ1 (PLCδ1) in complexes with the inositol-lipid headgroup and calcium identified residues within the catalytic domain that could be involved in substrate recognition, calcium binding, and catalysis. In addition, the structure of the PLCδ1 catalytic domain revealed a cluster of hydrophobic residues at the rim of the active site opening (hydrophobic ridge). To assess a role of each of these residues, we have expressed, purified, and characterized enzymes with the point mutations of putative active site residues (His311, Asn312, Glu341, Asp343, His356, Glu390, Lys438, Lys440, Ser522, Arg549, and Tyr551) and residues from the hydrophobic ridge (Leu320, Phe360, and Trp555). The replacements of most active site residues by alanine resulted in a great reduction (1,000–200,000-fold) of PLC activity analyzed in an inositol lipid/sodium cholate mixed micelle assay. Measurements of the enzyme activity toward phosphatidylinositol, phosphatidylinositol 4-monophosphate, and phosphatidylinositol 4,5-bis-phosphate (PIP2) identified Ser522, Lys438, and Arg549 as important for preferential hydrolysis of polyphosphoinositides, whereas replacement of Lys440selectively affected only hydrolysis of PIP2. When PLC activity was analyzed at different calcium concentrations, substitutions of Asn312, Glu390, Glu341, and Asp343 resulted in a shift toward higher calcium concentrations required for PIP2 hydrolysis, suggesting that all these residues contribute toward Ca2+binding. Mutational analysis also confirmed the importance of His311 (∼20,000-fold reduction) and His356(∼6,000-fold reduction) for the catalysis. Mutations within the hydrophobic ridge, which had little effect on PIP2hydrolysis in the mixed-micelles, resulted in an enzyme that was less dependent on the surface pressure when analyzed in a monolayer. This systematic mutational analysis provides further insights into the structural basis for the substrate specificity, requirement for Ca2+ ion, catalysis, and surface pressure/activity dependence, with general implications for eukaryotic phosphoinositide-specific PLCs.
Tuberculosis associated factors caused by Mycobacterium tuberculosis of the RDRio genotype

BACKGROUND Tuberculosis (TB) continues to be a disease that affects many countries around the world, including Brazil. Recently, a subtype of Latin American-Mediterranean family strain was identified and characterised by RDRio. The strain has been associated with different characteristics of the disease. OBJECTIVES In the present study we investigated the association of epidemiological, clinical, radiological and bacteriological variables with pulmonary tuberculosis caused by RDRio Mycobacterium tuberculosis strain in large regions of São Paulo. METHODS We conducted a cross-sectional study in 530 patients with pulmonary tuberculosis, diagnosed using sputum culture, from two regions of the São Paulo state in Brazil. The samples were brought to São Paulo reference laboratories for epidemiological, clinical, radiological and bacteriological analyses, and the data were obtained from a TB notification system. RDRio genotyping and Spoligotyping of the samples were performed. For the analysis of the categorical variables we used the chi-square test or the Fisher’s exact test, and for the continuous variables, the Mann-Whitney test. In addition, a logistic regression was used for multivariate analysis. Differences with p < 0.05 were considered significant. FINDINGS The RDRio deletion was identified in 152 (28.7%) samples. In the univariate analysis, both the age groups above 25 years and alcohol consumption were associated with the RDRio deletion. The multivariate analysis confirmed the association of the RDRio deletion with the age groups: 25-35 years old [OR: 2.28 (1.02-5.07; p = 0.04)] and 36-60 years old (OR: 2.36 (1.11-5.05); p = 0.03], and also with alcohol consumption [OR: 1.63 (1.05-2.54); p = 0,03]. MAIN CONCLUSIONS In this study, we identified new factors associated with the M. tuberculosis of the RDRio deletion strains infection.
Combination of Injectable Multiple Growth Factor-Releasing Scaffolds and Cell Therapy as an Advanced Modality to Enhance Tissue Neovascularization

Objective—Vasculogenic progenitor cell therapy for ischemic diseases bears great potential but still requires further optimization for justifying its clinical application. Here, we investigated the effects of in vivo tissue engineering by combining vasculogenic progenitors with injectable scaffolds releasing controlled amounts of proangiogenic growth factors. Methods and Results—We produced biodegradable, injectable polylactic coglycolic acid-based scaffolds releasing single factors or combinations of vascular endothelial growth factor, hepatocyte growth factor, and angiopoietin-1. Dual and triple combinations of scaffold-released growth factors were superior to single release. In murine hindlimb ischemia models, scaffolds releasing dual (vascular endothelial growth factor and hepatocyte growth factor) or triple combinations improved effects of cord blood-derived vasculogenic progenitors. Increased migration, homing, and incorporation of vasculogenic progenitors into the vasculature augmented capillary density, translating into improved blood perfusion. Most importantly, scaffold-released triple combinations including the vessel stabilizer angiopoietin-1 enhanced the number of perivascular smooth muscle actin+ vascular smooth muscle cells, indicating more efficient vessel stabilization. Conclusion—Vasculogenic progenitor cell therapy is significantly enhanced by in vivo tissue engineering providing a proangiogenic and provasculogenic growth factor-enriched microenvironment. Therefore, combined use of scaffold-released growth factors and cell therapy improves neovascularization in ischemic diseases and may translate into more pronounced clinical effects.
A comparative study of Grades 9-12 students' perceptions of teaching effectiveness in music class according to gender, years of enrollment, and music instrument played at the American School of Bangkok, Green Valley campus

The aims of this study were to identify Grades 9-12 students’ perceptions on teaching effectiveness of teachers in music class at the American School of Bangkok, Green Valley campus, and to determine whether there was a significant difference among these students’ perceptions according to their gender, years of enrollment, and music instrument played. This study focused on 81 Grades 9-12 students who enrolled music class at the American School of Bangkok, Green Valley campus, during the academic year 2016-2017. The students answered a questionnaire after learning to play and perform an instrument for at least a nine-month period. The research findings revealed that there was no significant difference among students’ perceptions according to all three demographic categories, gender, years of enrollment, and music instrument played, and suggested that Grades 9-12 students, regardless of their demographic differences, perceived teaching effectiveness of music class as very effective. Based on the findings, recommendations for students, teachers, administrators and future researchers were provided.
The Relationship between Curvature and Velocity in Two-Dimensional Smooth Pursuit Eye Movements

Curvature and tangential velocity of voluntary hand movements are constrained by an empirical relation known as the Two-Thirds Power Law. It has been argued that the law reflects the working of central control mechanisms, but it is not known whether these mechanisms are specific to the hand or shared also by other types of movement. Three experiments tested whether the power law applies to the smooth pursuit movements of the eye, which are controlled by distinct neural motor structures and a peculiar set of muscles. The first experiment showed that smooth pursuit of elliptic targets with various curvature–velocity relationships was most accurate when targets were compatible with the Two-Thirds Power Law. Tracking errors in all other cases reflected the fact that, irrespective of target kinematics, eye movements tended to comply with the law. Using only compatible targets, the second experiment demonstrated that kinematics per se cannot account for the pattern of pursuit errors. The third experiment showed that two-dimensional performance cannot be fully predicted on the basis of the performance observed when the horizontal and vertical components of the targets used in the first condition were tracked separately. We conclude that the Two-Thirds Power Law, in its various manifestations, reflects neural mechanisms common to otherwise distinct control modules.
Influences of number of adults and adult: child ratios on the quantity of adult language input across childcare settings

New approaches to examining the language environment are putting greater emphasis on the use of highly naturalistic audio recordings and questions about cross-cultural differences in children’s real-world language experiences. These new approaches and questions require careful examination of different kinds of variables that may influence children’s language experiences. The current study examines the influence of the number of adults and adult:child ratio on the number of words heard by young children across three childcare settings (home, home daycare and daycare centre). The home setting was characterized by a high number of one-on-one interactions, while children in daycare centres were exposed to larger numbers of adults present. While a linear relationship was found between the number/ratio of adults and words heard in the home setting, these relationships were more complex in daycare centres, and no relationships were found in home daycares.
Emotional expression and vocabulary learning in adults and children

A great deal of what we know about the world has not been learned via first-hand observation but thanks to others' testimony. A crucial issue is to know which kind of cues people use to evaluate information provided by others. In this context, recent studies in adults and children underline that informants' facial expressions could play an essential role. To test the importance of the other's emotions in vocabulary learning, we used two avatars expressing happiness, anger or neutral emotions when proposing different verbal labels for an unknown object. Experiment 1 revealed that adult participants were significantly more likely than chance to choose the label suggested by the avatar displaying a happy face over the label suggested by the avatar displaying an angry face. Experiment 2 extended these results by showing that both adults and children as young as 3 years old showed this effect. These data suggest that decision making concerning newly acquired information depends on informant's expressions of emotions, a finding that is consistent with the idea that behavioural intents have facial signatures that can be used to detect another's intention to cooperate.
Voice recognition based on adaptive MFCC and deep learning

In this paper, we propose an enhanced voice recognition method using Adaptive MFCC and Deep Learning. To improve the voice recognition rate, it is important to extract the audio data from original signal. However the existing Algorithms which is used to remove the noise of particular band deteriorate the audio signal. Differently from the existing MFCC, the proposed filter is built up compactly in the data density area to reduce data loss, and impose the weighted value to the data area. As a result, it prevents the data loss which results in improving the recognition rate. In addition the Deep Learning makes it possible to use the Voice recognition without DB. Therefore, it can be effectively used for electronic devices with small memory.
Molecular analysis of florfenicol-resistant Escherichia coli isolates from pigs.

OBJECTIVES The aim of this study was to analyse florfenicol-resistant Escherichia coli isolates from pigs for the genetic basis of florfenicol resistance, and to compare these data with those previously determined for E. coli isolates from cattle and poultry. METHODS Fourteen porcine E. coli isolates were included in this study and subjected to serotyping, plasmid profiling and macrorestriction analysis. MICs of florfenicol were determined by broth microdilution. The presence of the gene floR was confirmed by hybridization and PCR analysis. Transformation experiments were conducted to isolate florfenicol resistance plasmids. The floR region of a florfenicol resistance plasmid was cloned and sequenced. RESULTS All florfenicol-resistant E. coli isolates exhibited MICs of florfenicol >128 mg/L and carried the floR gene. A single isolate had a floR-carrying plasmid of approximately 35 kb, designated pMBSF1. Sequence analysis identified the floR gene flanked by truncated transposase genes. Moreover, a truncated copy of Tn5393 with complete streptomycin resistance genes strA and strB was found upstream of the floR gene of pMBSF1. Chromosomally resistant E. coli isolates, which shared the same BlnI macrorestriction pattern, differed in their floR hybridization patterns. CONCLUSION The plasmid pMBSF1 is the smallest floR-carrying plasmid reported to date. Its floR region differed from those previously found in E. coli isolates from cattle. Variations in the RFLPs of chromosomal EcoRI fragments carrying floR in isolates that had the same macrorestriction pattern might suggest variable chromosomal integration sites.
Political Psychology of European Integration: The (Re)production of Identity and Difference in the Brexit Debate

This article uses political psychology to understand emotions such as anger, hate, and passion in the Brexit debate in order to demonstrate the wider value of the political psychology of European integration. It uses five strands of political psychology to understand European integration, drawing on evidence from the Brexit debate. These strands are individual cognitive psychology, social psychology, social construction, psychoanalysis, and critical political psychology. The article argues that the political psychology of European integration demands an understanding of the interwoven nature of feelings and illusions, the bidirectional interaction of political and psychological processes, and the multiplicity of strands of political psychology in the mutual accommodation and inclusion by European states and peoples. Only in this way is it possible to even begin to comprehend the many ways in which identity and difference are (re)produced by all partners in the Brexit debate and what these processes mean for the wider study of the political psychology of European integration. (Less)
Arms Races and Negotiations

A state which does not desire an arms race may nevertheless acquire new weapons if it believes another state will acquire them. If each state assigns some arbitrarily small probability to the event that the other state has a dominant strategy to acquire more weapons, then a multiplier effect appears, and the unique Bayesian Nash equilibrium involves an arms race with probability one. However, if the prior probability that a player is a dominant strategy type is sufficiently small, then there is an equilibrium of the cheap-talk extension of the arms race game where the probability of an arms race is close to zero.
L’innovation pédagogique en question : analyse des discours de praticiens

L’innovation pedagogique resonne comme une injonction generale dans l’enseignement superieur aujourd’hui. Mais les pratiques et les discours montrent que cette expression recouvre des realites assez differentes, en termes de finalites, d’usages et de conceptions ideologiques. Une etude des actes du colloque Questions de pedagogie dans l’enseignement superieur, « Innover : comment et pourquoi ? », selon la methode de l’analyse du discours, est ici proposee pour donner a voir les conceptions vehiculees par les pedagogues praticiens, enseignants et chercheurs. Cette etude met en valeur les caracteristiques les plus repandues de ce que les auteurs considerent comme innovation pedagogique, autour de la production des outils et de la volonte d’adapter les etudiants aux realites sociales, economiques et culturelles contemporaines. S’en degage une approche largement partagee, de type pragmatique et positiviste, presentant l’innovation pedagogique plutot comme une adaptation aux conditions du marche de l’enseignement superieur et de l’emploi, que comme un moyen d’emancipation intellectuelle et morale des etudiants.
Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model

Oral administration of royal jelly (RJ) promotes wound healing in diabetic mice. Concerns have arisen regarding the efficacy of RJ on the wound healing process of normal skin cells. In this study, a wound was created by scratching normal human dermal fibroblasts, one of the major cells involved in the wound healing process. The area was promptly treated with RJ at varying concentrations of 0.1, 1.0, or 5 mg/ml for up to 48 hrs and migration was analyzed by evaluating closure of the wound margins. Furthermore, altered levels of lipids, which were recently reported to participate in the wound healing process, were analyzed by HPTLC and HPLC. Migration of fibroblasts peaked at 24 hrs after wounding. RJ treatment significantly accelerated the migration of fibroblasts in a dose-dependent manner at 8 hrs. Although RJ also accelerated the migration of fibroblasts at both 20 hrs and 24 hrs after wounding, the efficacy was less potent than at 8 hrs. Among various lipid classes within fibroblasts, the level of cholesterol was significantly decreased at 8 hrs following administration of both 0.1 ug/ml and 5 mg/ml RJ. Despite a dose-dependent increase in sphinganines, the levels of sphingosines, ceramides, and glucosylceramides were not altered with any concentration of RJ. We demonstrated that RJ enhances the migration of fibroblasts and alters the levels of various lipids involved in the wound healing process.