Miracle-dz/UniFAR-FTUs huggingface dataset:
To What Extent is the Experience of Empathy Mediated by Shared Neural Circuits?

This paper selectively reviews the neurophysiological evidence for shared neural circuits (supposedly implemented by mirror neurons) as the mechanism underlying empathy. I will argue that while the mirror neuron system plays a role in motor resonance, it is not possible to conclude that this system is critically involved in emotion recognition, and there is little evidence for its role in empathy and sympathy. In addition, there is modest support from neurological observations that lesion of the regions involved in the mirror neuron system leads to dysfunction in empathy, whereas damage of the ventromedial prefrontal cortex is associated with such impairment. To significantly advance our understanding of the mechanisms underlying empathy, research needs finer conceptualization, better designed paradigms, and integration with knowledge from lesion studies.
Cognition and laterality in untreated hemiparkinsonism

Abstract Twelve patients with idiopathic Parkinson's disease on only one side of the body were studied using various tests evaluating cognitive, memory, and psychomotor functions. All patients were untreated. The affected side was associated with impaired performance in motor and psychomotor tests but not in most of the tests to evaluate general cognitive capacity (WAIS) and memory (WMS). Patients with left hemiparkinsonism performed less well in the Picture Completion test of the WAIS and in the Stroop test (parts 3 and 3-2) than did subjects with right hemiparkinsonism. The results were interpreted as supporting the view that dopaminergic structures predominantly of the right hemisphere may be involved in the attention/activation process.
Integration methods for the calculation of the magnetostatic field due to coils

Integration methods for the calculation of the magnetostatic field due to coils Marzia Fontana Abstract Analytical and numerical integration methods of the Biot-Savart law are presented for the three-dimensional computation of the magnetic eld generated by stationary currents. For complex-shaped conductors a nite volume approximation is proposed, based on a composite Gauss-Legendre quadrature on tetrahedral subdo-mains of the conductors. For circular coils with rectangular cross section, a modiied semi-analytical Urankar's method is considered, expressed in terms of elementary functions, Jacobian elliptic functions and complete/incomplete elliptic integrals of the rst, second and third kind. As alternative, numerical integration can be applied to sequences of one-dimensional non-singular integrals in azimuthal coordinate. For massive computation on a large number of eld points, an optimized integration scheme for coils is suggested, by combining the modiied Urankar's method with one-dimensional numerical integration. Numerical examples are reported on signiicant test cases for a comparison among the several integration methods proposed.
12 Entrepreneurship: A Field of Dreams?

Abstract This paper has two objectives. We begin by contrasting two potential paths for future research in entrepreneurship. One is the establishment of an independent field of research with a clear jurisdiction, a common theoretical canon, and autonomy from related fields. The second is a phenomena‐based approach, in which scholars congregate around common interests in empirical phenomena but approach them with distinct disciplinary lenses. After discussing these alternatives and lobbying for the phenomena‐based approach, we then review some of the recent, discipline‐based research in economic and organizational sociology relevant to entrepreneurship, and identify significant gaps in that literature.
BEHAVIORAL FREQUENCY JUDGMENTS - AN ACCESSIBILITY DIAGNOSTICITY FRAMEWORK

Marketing research surveys often elicit behavioral frequency reports. When estimating the number of times a respondent engages in a behavior, s/he may use information about the behavior stored in memory, information provided by the response context, or both. Based on an accessibility-diagnosticity framework, we theorize that the probability of using context-based information in forming a frequency judgment is inversely proportional to the diagnosticity of the alternative inputs accessible in memory. That is, when memory-based information is accessible and diagnostic, contextual information is not used; when memory-based information is accessible but not diagnostic, the use of contextual information depends on its perceived diagnosticity. Finally, when memory-based information is not accessible, contextual information is used even when its diagnosticity is questionable. The results of three experiments support this model. Theoretical implications and recommendations for questionnaire design are discussed. Copyright 1995 by the University of Chicago.
Recidivism in pedophiles: an investigation using different diagnostic methods

The relationship between pedophilia and recidivism was examined in a sample of 206 extra-familial child molesters assessed at a university teaching hospital between 1982 and 1992. To address definitional issues, pedophilia was defined in one of four ways: (1) a DSM diagnosis made by a psychiatrist; (2) a deviant phallometric profile; (3) a combination of DSM diagnosis and deviant phallometric results; and, (4) high scores based on the Screening Scale for Pedophilic Interest (SSPI; Seto & Lalumière, 2001). Of the various definitions for pedophilia only phallometric assessment (PAI) distinguished between sexual recidivists and nonrecidivists. Overall recidivism rates were 22.8%, 33.9%, and 45.6% for sexual, violent, and any reoffence, respectively. No differences were found between pedophiles and nonpedophiles with respect to recidivism rates, regardless of how pedophilia was defined. Based on these results, the utility of the DSM diagnosis of pedophilia for the purpose of predicting future reoffending is discussed.
Electrocardiograph and chest X-ray in prediction of left ventricular systolic dysfunction.

INTRODUCTION Echocardiography is the definitive diagnostic tool for left ventricular systolic dysfunction. But it's expensive and requires trained manpower and thus might not be available in the primary care set up. ECG and Chest X ray, the more basic investigations, may help diagnose LVSD or at least streamline those who absolutely require echocardiography in primary care setup. METHODS ECG, Chest X ray and Echocardiography along with clinical assessment were performed on 35 patients with some form of complaints related to heart. The inferences on systolic function obtained from ECG, Chest X ray were compared with Echocardiography findings. RESULTS Out of 35 participants, 25 had left ventricular ejection fraction less than 45%, 28 had abnormal ECG, 30 had cardiomegaly in chest X-ray. A set of pre-selected ECG abnormalities had a sensitivity of 100% (83.4-100), specificity of 70% (35.4-91.9) and a positive predictive value of 89.3% (70.6-97.2) in diagnosing LVSD. Likewise, the figures were 92% (72.5-98.6), 30% (8.1-64.6) and 76.7% (57.3-89.4) respectively for a cardio-thoracic ratio of more than 0.5 in chest X-ray. CONCLUSIONS Although, ECG and Chest X ray could not replace Echocardiography, they could very well give an idea of the systolic function of an individual and suggest the need or no need for an echo-study in primary care setup.
The effect of TENS on pain, function, depression, and analgesic consumption in the early postoperative period with spinal surgery patients.

AIM The aim of our study was to examine the effects of the use of Transcutaneous Electrical Nerve Stimulation (TENS) in patients who had undergone spinal surgery on pain, functionality, depression and consumption of analgesic agents. MATERIAL AND METHODS Fifty-Four patients were randomized and placed into two groups, patient-controlled analgesia (PCA) plus TENS and only PCA. To assess the pain levels of the patients, the Visual Analog Scale (VAS) was used. In the assessment of their functional levels, the Timed Up and Go test (TUG) was utilized and in the assessment of their depression, the Beck Depression Inventory (BDI) was used. The measurements were performed before the operation and on the first and second postoperative days. The side effects were recorded from the analgesic agents. RESULTS During the first and second days after the operation, a decrease in the pain levels was noticed in the TENS group (p < 0.05. In the TENS group, the consumption of analgesic agents also decreased and thus side effects were less frequent. From the viewpoint of functional and depression levels, no significant difference between the groups was noticed (p > 0.05). CONCLUSION TENS was effective in reducing analgesic agent-related side effects and in reducing analgesic consumption. In addition, TENS also decreased activity related pain.
Patterns of marital change during the early childhood years: Parent personality, coparenting, and division-of-labor correlates.

Cluster analysis was applied to the marital reports of 99 husbands and wives (from 104 families) obtained when their firstborn sons were 10, 27, 36, and 60 months of age to identify distinct patterns of change in marital functioning. Husband-love and wife-conflict scores revealed 3 distinct change patterns-stays good, bad to worse, and good gets worse-which afforded the opportunity to address 2 distinct questions, the 1st dealing with the correlates of consistently good and poor functioning marriages and the 2nd with what distinguishes marriages that initially functioned similarly (and well) but proceeded to develop in distinctively different ways. Results show, consistent with related findings from a study of newlyweds (B. Kamey & T. Bradbury, 1997), that the answer to the 1st question is found in enduring personality traits of spouses, whereas the answer to the 2nd is found in observed marital dynamics (reflecting coparenting processes).
Role of Impression Cytology in Diagnosis of Ocular Surface Neoplasia

Purpose: To compare the accuracy of impression cytology in the diagnosis of ocular surface neoplasia with tissue histology. Methods: We reviewed the histories of patients diagnosed with ocular surface neoplasia at the Chiang Mai University Hospital. All patients underwent both impression cytology and tissue biopsy. We compared the results of both methods. Results: There were 55 patients (33 men and 22 women), with an age range of 12-99 years (mean, 51 years). Twenty patients had lesions in the right eye and 35 had them in the left eye. The most common histologic report was conjunctival-corneal intraepithelial neoplasia (38.2%), followed by squamous cell carcinoma (34.5%), nonneoplastic changes of squamous epithelia (10.9%), squamous papilloma (7.3%), conjunctival nevi (7.3%), and malignant melanoma (1.8%). Compared with histologic findings, the positive and negative predictive accuracy of impression cytology was 97.4% and 52.9%, respectively. For squamous neoplasms, squamous cell carcinoma had the highest correlation with histology. The presence of dysplastic cells suggested malignancy. Conclusions: This study shows that impression cytology might have a promising role in diagnosing ocular surface neoplasia for its high positive predictive accuracy compared with tissue histology. However, a fair negative predictive accuracy indicates that impression cytology is a valuable screening technique, but it is not a “gold standard. ”
Factors Associated With Frequent Emergency Department Use in the Medicare Population

Frequent emergency department (ED) use is a public health and policy relevant concern but has not previously been examined in the Medicare population. We conducted a retrospective, claims-based analysis of a nationally representative 20% sample of fee-for-service Medicare beneficiaries in 2010 (n = 5,778,038) to examine frequent ED use. We used multinomial logistic regression to study the relationship between frequent ED use and sociodemographic, outpatient care, and clinical characteristics. Factors that were most strongly associated with frequent ED use included being age 18 to 34 years compared with 65 to 74 years (relative risk ratio = 20.5, confidence interval [CI; 19.7, 21.3]) and mental illness (relative risk ratio = 6.8, CI [6.7, 6.9]). Low versus high continuity of care was associated with 24% (95% CI [1.21, 1.26]) greater risk of frequent compared with non-ED use. Although clinical and demographic characteristics are most strongly associated with frequent ED use, poor continuity of care is also a contributor.
CRM1- and Ran-independent nuclear export of beta-catenin.

BACKGROUND Activation of the Wnt pathway induces beta-catenin to localize inside the nucleus, where it interacts with transcription factors such as TCF/LEF-1. Regulation of the pathway occurs through a beta-catenin-degrading complex based on Axin and the tumor suppressor APC. We have previously found that beta-catenin import occurs independently of nuclear import factors but is similar to the import of the transport factors themselves do. APC, which can shuttle in and out of the nucleus, has been proposed to be responsible for reexport of beta-catenin in a CRM1-dependent manner. RESULTS We have studied beta-catenin export in vivo and in semipermeabilized cells. beta-catenin contains three export sequences. Export is insensitive to leptomycin B, a specific inhibitor of the CRM1-mediated pathway. It does not require nuclear RanGTP, and it can be reconstituted in the absence of additional soluble factors; this is consistent with nondirectional translocation of beta-catenin. Further observations suggest that beta-catenin subcellular distribution in vivo may depend primarily on retention through interaction with other cellular components. Finally, we show evidence that reexport is required for degradation of nuclear beta-catenin and that nuclei lack Axin, an essential component of the degradation machinery. CONCLUSIONS beta-catenin is exported independently of the CRM1 pathway. We propose a model of free, nondirectional nuclear translocation for beta-catenin, its localization being regulated by retention in the nucleus and degradation in the cytoplasm.
Worlds Apart? English in German Youth Cultures and in Educational Settings.

: This paper focuses on German teenagers and their contact with English in two different contexts: in free-time activities typically involving the mass media, and in institutionalised language learning settings at school. It draws on an empirical study carried out in German secondary schools. Its mixed methods approach combines a questionnaire study and focus group interviews with 15-year-old students and English teachers. The main aim of the enquiry was to find out how teenagers experience learning English in school in the light of their exposure to the language in their free time. Another focus lies on the teachers' perceptions of their students' contact with English outside school and on their practice in the classroom as to whether and how they use this experience in class. The data suggests that out-of-class contact with English is often not integrated into the EFL classroom. Thus, the classroom and the students' free time seem to be, by and large, two separate spheres, involving different methods of exposure to English in terms of text types, topics, activities, and language varieties.
Large-scale extraction and use of knowledge from text

Many AI tasks, in particular natural language processing, require a large amount of world knowledge to create expectations, assess plausibility, and guide disambiguation. However, acquiring this world knowledge remains a formidable challenge. Building on ideas by Schubert, we have developed a system called DART (Discovery and Aggregation of Relations in Text) that extracts simple, semi-formal statements of world knowledge (e.g., "airplanes can fly", "people can drive cars") from text by abstracting from a parser's output, and we have used it to create a database of 23 million propositions of this kind. An evaluation of the DART database on two language processing tasks (parsing and textual entailment) shows that it improves performance, and a human evaluation shows that over half the facts in it are considered true or partially true, rising to 70% for facts seen with high frequency. The significance of this work is two-fold: First it has created a new, publically available knowledge resource for language processing and other data interpretation tasks, and second it provides empirical evidence of the utility of this type of knowledge, going beyond Schubert et al's earlier evaluations which were based solely on human inspection of its contents.
Correlation Between the Expression of an Escherichia coli Cell Surface Protein and the Ability of the Protein to Bind to Lipopolysaccharide

The ompA gene of Escherichia coli codes for a major protein of the outer membrane. When this gene was moved between various unrelated strains (E. coli K-12 and two clinical isolates of E. coli) by transduction, the gene was expressed very poorly. Recombinants carrying “foreign” genes produced no OmpA protein which could be detected on polyacrylamide gels and became resistant to bacteriophage K3, which uses this protein as receptor. The recombinants were sensitive to host-range mutants of K3, indicating a very low level of OmpA protein was produced. When an E. coli K-12 recombinant carrying an unexpressed foreign ompA allele was subjected to two cycles of selection for an OmpA+ phenotype, a mutant strain was obtained which was sensitive to K3 and which expressed nearly normal levels of OmpA protein in the outer membrane. This strain carried mutations in the foreign ompA gene, as indicated both by genetic mapping and the alteration of a peptide in the mutant OmpA protein. The ability of the OmpA protein to bind to lipopolysaccharide (LPS) showed similar strain specificity, and the mutant OmpA protein which was expressed in an unrelated host showed enhanced ability to bind LPS from its new host. Thus, cell surface expression of the ompA gene appears to depend upon the ability of the gene product to bind LPS, suggesting that an interaction between the protein and LPS plays an essential role in biosynthesis of this outer membrane protein.
A Biologically Inspired Computational Model of Basal Ganglia in Action Selection

The basal ganglia (BG) are a subcortical structure implicated in action selection. The aim of this work is to present a new cognitive neuroscience model of the BG, which aspires to represent a parsimonious balance between simplicity and completeness. The model includes the 3 main pathways operating in the BG circuitry, that is, the direct (Go), indirect (NoGo), and hyperdirect pathways. The main original aspects, compared with previous models, are the use of a two-term Hebb rule to train synapses in the striatum, based exclusively on neuronal activity changes caused by dopamine peaks or dips, and the role of the cholinergic interneurons (affected by dopamine themselves) during learning. Some examples are displayed, concerning a few paradigmatic cases: action selection in basal conditions, action selection in the presence of a strong conflict (where the role of the hyperdirect pathway emerges), synapse changes induced by phasic dopamine, and learning new actions based on a previous history of rewards and punishments. Finally, some simulations show model working in conditions of altered dopamine levels, to illustrate pathological cases (dopamine depletion in parkinsonian subjects or dopamine hypermedication). Due to its parsimonious approach, the model may represent a straightforward tool to analyze BG functionality in behavioral experiments.
Does Artistic Creativity Decline during Elementary School?

Some psychologists have argued that artistic creativity declines during the elementary school years. This hypothesis was tested by having 108 students in kindergarten and Grades 3, 4, and 5 produce collages which were then judged for creativity using a consensual assessment technique. Contrary to the hypothesis of a creative decline, artistic creativity on this collage-making task as rated by 18 undergraduate art education students was higher among older elementary school students.
Perceptual Learning Incepted by Decoded fMRI Neurofeedback Without Stimulus Presentation

Even the adult primary visual cortex is sufficiently plastic to allow performance enhancement. It is controversial whether the adult primate early visual cortex is sufficiently plastic to cause visual perceptual learning (VPL). The controversy occurs partially because most VPL studies have examined correlations between behavioral and neural activity changes rather than cause-and-effect relationships. With an online-feedback method that uses decoded functional magnetic resonance imaging (fMRI) signals, we induced activity patterns only in early visual cortex corresponding to an orientation without stimulus presentation or participants’ awareness of what was to be learned. The induced activation caused VPL specific to the orientation. These results suggest that early visual areas are so plastic that mere inductions of activity patterns are sufficient to cause VPL. This technique can induce plasticity in a highly selective manner, potentially leading to powerful training and rehabilitative protocols.
Benefit of Kupffer cell modulation with glycine versus Kupffer cell depletion after liver transplantation in the rat: effects on postischemic reperfusion injury, apoptotic cell death graft regeneration and survival *

Inhibition or destruction of Kupffer cells (KC) may protect against ischemia‐reperfusion (IR) induced primary graft nonfunction (PNF) in liver transplantation. Besides KC activation, PNF is characterized by microvascular perfusion failure, intrahepatic leukocyte accumulation, cell death and hepatocellular dysfunction. KCs can be inactivated by different agents including gadolinium chloride (GdCl3), methyl palmitate (MP) and glycine. The effects of three KC inactivators on IR‐injury after rat liver transplantation were compared in the present study. Lewis liver donors were treated with GdCl3, MP, glycine or saline (control). Liver grafts were transplanted following 24 h storage (UW solution). KC populations and IR damage were assessed by histologic analysis, quantitative real‐time polymerase chain reaction (RT‐PCR) and intravital microscopy. The number of hepatic ED‐1 positive macrophages was diminished after GdCl3 (114.8 ± 4.4/mm2 liver tissue) and MP treatment (176.0 ± 5.0), versus the glycine (263.9 ± 5.5) and control (272.1 ± 5.6) groups. All three treatment modalities downregulated phagocytic activity for latex particles, paralleled by reduced microvascular injury (acinar perfusion index, GdCl3: 0.75 ± 0.03; MP: 0.83 ± .03; glycine: 0.84 ± 0.03; 0.63 ± 0.03). Quantitative RT‐PCR revealed elevated myeloperoxidase mRNA after glycine versus GdCl3 and MP pretreatment (3.2‐ and 3.4‐fold, P = 0.011, respectively), without difference to controls (2.9‐fold of glycine). TNFα‐mRNA was reduced after glycine‐ (5.2‐fold), GdCl3‐ (19.7‐fold), MP‐treatment (39.5‐fold) compared with controls. However, profound prevention of intrahepatic cell death and liver graft failure was solely achieved with glycine preconditioning. Different than GdCl3 and MP, glycine modulates rather than destroys KCs. Glycine appears to preserve cell viability and to TNFα/leukocyte dependent organ regeneration capacity, which is related to increase graft survival following liver transplantation.