Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards an information-centric delay-tolerant network

Information-centric networks (ICNs) have emerged as a prominent future Internet architecture. They work on the principle that, in today's society, a network should be optimised towards the delivery of information, rather than the transit of messages between pre-determined end hosts. At the same time, another prominent research direction has been the delay-tolerant networking initiative, which argues that networks must explicitly support the tolerance of high delays and disruptions in end-to-end paths. We believe that this observation is pervasive across a number of applications and network technologies and should therefore be strongly considered in any future ICN designs. This paper explores the potential of combining these concepts into an information-centric delay-tolerant network (ICDTN). Through a qualitative and quantitative investigation, we present arguments in favour of the design, as well as important research challenges.
How Do Stocks React to Extreme Market Events? Evidence from Brazil

This paper studies the short-term (21 trading days) behavior of Brazilian stocks in the event of extreme movements in the Brazilian market index. Using cumulative abnormal returns, we find that stocks tend to overreact after both positive and negative events, as well as global and domestic shocks. Interestingly, this behavior is particularly intense when the events are not clustered. This counterintuitive finding can be explained by the Contrast Hypothesis, since shocks during calm circumstances can be viewed by investors as more surprising. In fact, when we split events according to market volatility, we document a stronger overreaction when volatility is low.
Optical-Wireless Integration: Technologies for Physical Layer Networking

In this paper, we present a review of physical layer networking options and enabling system technologies for efficient integration of optical and wireless access network infrastructure. We discuss that by exploiting the optical access network and its future evolutions for providing effective backhaul for wireless access, a unified backbone network capable of supporting an integrated offering of both wired and wireless broadband access can easily be achieved.
Competition between Phasic and Asynchronous Release for Recovered Synaptic Vesicles at Developing Hippocampal Autaptic Synapses

Developing hippocampal neurons in microisland culture undergo rapid and extensive transmitter release-dependent depression of evoked (phasic) excitatory synaptic activity in response to 1 sec trains of 20 Hz stimulation. Although evoked phasic release was attenuated by repeated stimuli, asynchronous (miniature like) release continued at a high rate equivalent to ∼2.8 readily releasable pools (RRPs) of quanta/sec. Asynchronous release reflected the recovery and immediate release of quanta because it was resistant to sucrose-induced depletion of the RRP. Asynchronous and phasic release appeared to compete for a common limited supply of release-ready quanta because agents that block asynchronous release, such as EGTA-AM, led to enhanced steady-state phasic release, whereas prolongation of the asynchronous release time course by LiCl delayed recovery of phasic release from depression. Modeling suggested that the resistance of asynchronous release to depression was associated with its ability to out-compete phasic release for recovered quanta attributable to its relatively low release rate (up to 0.04/msec per vesicle) stimulated by bulk intracellular Ca2+ concentration ([Ca2+]i) that could function over prolonged intervals between successive stimuli. Although phasic release was associated with a considerably higher peak rate of release (0.4/msec per vesicle), the [Ca2+]i microdomains that trigger it are brief (1 msec), and with asynchronous release present, relatively few quanta can accumulate within the RRP to be available for phasic release. We conclude that despite depression of phasic release during train stimulation, transmission can be maintained at a near-maximal rate by switching to an asynchronous mode that takes advantage of a bulk presynaptic [Ca2+]i.
V1647 ORIONIS: REINVIGORATED ACCRETION AND THE RE-APPEARANCE OF MCNEIL'S NEBULA

In late 2003, the young eruptive variable star V1647 Orionis optically brightened by over 5 mag, stayed bright for around 26 months, and then declined to its pre-outburst level. In 2008 August, the star was reported to have unexpectedly brightened yet again and we herein present the first detailed observations of this new outburst. Photometrically, the star is now as bright as it ever was following the 2003 eruption. Spectroscopically, a pronounced P Cygni profile is again seen in Hα with an absorption trough extending to −700 km s−1. In the near-infrared, the spectrum now possesses very weak CO overtone bandhead absorption in contrast to the strong bandhead emission seen soon after the 2003 event. Water vapor absorption is also much stronger than previously seen. We discuss the current outburst below and relate it to the earlier event.
Is curriculum in the closet? Instructors' perceptions about gay and lesbian content in Alberta university gender courses

This study focuses on the nature of university instructors' beliefs and attitudes toward gay and lesbian content in the university Gender course curriculum. It was intended to provide a better understanding of factors such as academic freedom, societal influences, personal opinions, curriculum, and institutional influences that might affect attitudes and thus undermine the inclusion of discussion about Lesbian, Gay, Bisexual, and Transgender (LGBT) issues. Participants in the study were seven instructors from the faculties of Social Sciences, Faculty of Education, Applied Psychology, and Educational Psychology at the University of Alberta, the University of Calgary, and the University of Lethbridge, in the province of Alberta, Canada. The study revealed that although there was only a slight diversity of beliefs and attitudes about the topic among the participants, a majority of them felt positively toward inclusion of information in the university curricula. The positive attitudes were expressed as a willingness to teach about the subject matter, and a belief that LGBT content should be integrated throughout the general curriculum. The implications and the challenges of incorporating LGBT issues into the curriculum were also discussed. Participants discuss that LGBT issues are not adequately represented in the curriculum, that there is a need for more public awareness and education about homosexuality, a need for greater inclusion of gay and lesbian issues in university programs, a desire for less marginalization of the LGBT topic, and a vow to provide more respect for LGBT persons.
Serum biomarkers combined with uterine artery Doppler in prediction of preeclampsia

First-trimester screening may be a major advantage over a second-trimester approach since it opens prospects for early and more efficient interventions. The aim of the current study was to evaluate whether the measurement of maternal serum inhibin A, activin A and placental growth factor (PlGF) at three to four months gestation with the second-trimester uterine artery pulsatility index (PI) are useful in predicting preeclampsia in a group of nulliparous women. All the patients also underwent uterine artery Doppler examination to measure the PI at 22–24 weeks gestation. Inhibin A, activin A and PlGF were measured using an ELISA by an examiner who was blinded to the pregnancy outcome. Thirty-eight cases with preeclampsia and 100 controls were analyzed. Second-trimester uterine artery PI and marker levels were expressed as multiples of the median (MoM). The uterine artery PI was increased in pregnancies with preeclampsia compared with controls. In pregnancies that developed preeclampsia, the uterine artery PI was increased (1.61±0.047 vs. 1.02±0.049, P<0.001), as was the level of inhibin A (1.72±0.023 vs. 1.03±0.063, P<0.001) and the level of activin A (1.68±0.38 vs. 1.06±0.42, P<0.001) compared with the controls. In contrast, the level of PlGF was decreased in pregnancies that developed preeclampsia compared with the controls (0.69±0.23 vs. 1.00±0.26, P<0.001). A combination of activin A, PlGF and uterine artery PI gave an AUC of 0.915 (95% CI, 0.812–0.928; P<0.001) with a sensitivity of 91% at a specificity of 82%. In our study, we demonstrated that both serum inhibin A and activin A levels were increased, while the PlGF level was decreased in the early second-trimester in women who developed preeclampsia.
An eigenspace projection clustering method for inexact graph matching

In this paper, we show how inexact graph matching (that is, the correspondence between sets of vertices of pairs of graphs) can be solved using the renormalization of projections of the vertices (as defined in this case by their connectivities) into the joint eigenspace of a pair of graphs and a form of relational clustering. An important feature of this eigenspace renormalization projection clustering (EPC) method is its ability to match graphs with different number of vertices. Shock graph-based shape matching is used to illustrate the model and a more objective method for evaluating the approach using random graphs is explored with encouraging results.
The Kingdom and the Glory: For a Theological Genealogy of Economy and Government (Homo Sacer II, 2)

Why has power in the West assumed the form of an "economy," that is, of a government of men and things? If power is essentially government, why does it need glory, that is, the ceremonial and liturgical apparatus that has always accompanied it? In the early centuries of the Church, in order to reconcile monotheism with God's threefold nature, the doctrine of Trinity was introduced in the guise of an economy of divine life. It was as if the Trinity amounted to nothing more than a problem of managing and governing the heavenly house and the world. Agamben shows that, when combined with the idea of providence, this theological-economic paradigm unexpectedly lies at the origin of many of the most important categories of modern politics, from the democratic theory of the division of powers to the strategic doctrine of collateral damage, from the invisible hand of Smith's liberalism to ideas of order and security.But the greatest novelty to emerge from The Kingdom and the Glory is that modern power is not only government but also glory, and that the ceremonial, liturgical, and acclamatory aspects that we have regarded as vestiges of the past actually constitute the basis of Western power. Through a fascinating analysis of liturgical acclamations and ceremonial symbols of power-the throne, the crown, purple cloth, the Fasces, and more-Agamben develops an original genealogy that illuminates the startling function of consent and of the media in modern democracies. With this book, the work begun with Homo Sacer reaches a decisive point, profoundly challenging and renewing our vision of politics.
A prospective study of the pressure ulcer scale for healing (PUSH).

BACKGROUND Although the recently developed Pressure Ulcer Scale for Healing (PUSH) was created to monitor healing over time, prospective evidence of its validity in measuring healing is lacking. The purpose of this study was to assess the validity of PUSH (version 3.0) when used to assess pressure ulcers in clinical practice. METHODS The authors chose a prospective research design using a convenience sample of nursing home residents with pressure ulcers. The patients' pressure ulcers were assessed each week with the PUSH and the Pressure Sore Status Tool. Surface area measurements derived from wound tracings were also obtained. Weekly assessments continued until the ulcer healed, the resident died, the resident transferred from the nursing home, or 6 months of assessments were complete. RESULTS Thirty-two pressure ulcers comprised the study sample. Twenty-one (66%) healed during the 6-month study period and 11 (34%) did not heal. The PUSH scores decreased significantly over time among the healed ulcers but did not among the unhealed ulcers. Similarly, PUSH scores were significantly lower among the healed compared with the unhealed ulcers. Finally, total scores on PUSH were highly correlated with both the Pressure Sore Status Tool and surface area measurements. CONCLUSIONS The PUSH provides a valid measure of pressure ulcer healing over time and accurately differentiates a healing from a nonhealing ulcer. It is a clinically practical, evidence-based tool for tracking changes in pressure ulcer status when applied at weekly intervals.
Vision-based coaching: optimizing resources for leader development

Leaders develop in the direction of their dreams, not in the direction of their deficits. Yet many coaching interactions intended to promote a leader’s development fail to leverage the benefits of the individual’s personal vision. Drawing on intentional change theory, this article postulates that coaching interactions that emphasize a leader’s personal vision (future aspirations and core identity) evoke a psychophysiological state characterized by positive emotions, cognitive openness, and optimal neurobiological functioning for complex goal pursuit. Vision-based coaching, via this psychophysiological state, generates a host of relational and motivational resources critical to the developmental process. These resources include: formation of a positive coaching relationship, expansion of the leader’s identity, increased vitality, activation of learning goals, and a promotion–orientation. Organizational outcomes as well as limitations to vision-based coaching are discussed.
Effects of chronic hypercapnia on electrolyte and acid-base equilibrium. II. Recovery, with special reference to the influence of chloride intake.

Previous studies in both the rat (1, 2) and the dog (3) have demonstrated that chronic respiratory acidosis induces profound alterations in electrolyte balance, but little is known concerning the changes that occur when the stimulus of hypercapnia is withdrawn. The present experiments were undertaken in order to define the process of recovery, and to determine how it is influenced by the availability of sodium and chloride in the diet. For this purpose, balance studies were carried out in dogs returned to room air after a long period of exposure to a high CO2 atmosphere.
Nocardia brasiliensis Induces Formation of Foamy Macrophages and Dendritic Cells In Vitro and In Vivo

Foamy cells have been described in various infectious diseases, for example in actinomycetoma induced by Nocardia brasiliensis. These cells are generally considered to be macrophages, although they present dendritic cell (DC)-specific surface markers. In this study, we determined and confirmed the lineage of possible precursors of foamy cells in vitro and in vivo using an experimental actinomycetoma model in BALB/c mice. Bone marrow-derived macrophages (BMDM) or DC (BMDC) were infected in vitro with N. brasiliensis or labeled with carboxyfluorescein diacetate succinimidyl ester (CFSE). Both, macrophages and DC, differentiated into foamy cells after in vitro infection. CFSE-labeled BMDM or BMDC were tested for phagocytosis and CD11c/CD11b receptors markers expression before being transferred into the actinomycetoma lesion site of infected mice. In vivo studies showed that BMDM and BMDC were traced at the site where foamy cells are present in the experimental actinomycetoma. Interestingly, many of the transferred BMDM and BMDC were stained with the lipid-droplet fluorophore Nile Red. In conclusion, macrophages and DC cells can be differentiated into foamy cells in vitro and in vivo during N. brasiliensis infection.
Optimal Sample Allocation in Group-Randomized Mediation Studies with a Group-Level Mediator

Abstract We derive sample-allocation formulas that maximize the power of several mediation tests in two-level–group-randomized studies under a linear cost structure and fixed budget. The results suggest that the optimal individual sample size is typically smaller than that associated with the detection of a main effect and is frequently less than 10 under parameter values commonly seen in the literature. However, the optimal sample allocation can be heavily influenced by the group-to-individual cost ratio, the ratio of the treatment-mediator to mediator-outcome path coefficients, and the outcome variance structure. We illustrate these findings with a hypothetical group-randomized trial examining a school-discipline reform policy. To encourage utilization of the sample allocation formulas we implement them in the R package PowerUpR and powerupr Shiny application.
Educational Innovations in Multiracial Contexts: The Growth of Magnet Schools in American Education.

A study of magnet schools revealed that they have become a significant part of the nation's efforts to desegregate schools. Most magnet schools are in urban areas and offer a distinctive curriculum. School districts began employing mag-at schools in the 1970s to help desegregate schools. The federal government has assisted magnet schools with funding. This report is designed to study magnet schools, their role in desegregation, and their impact on educational achievement. Telephone interviews were conducted with educators at 600 school districts nationwide. The study revealed that magnet schools are increasing in number and attracting more students, including minority students and students from outside the school's immediate area. They offer a wide range of distinctive programs. Many magnet schools use money from the federal Magnet Schools Assistance Program to help set up and maintain their programs. This report contains six sections: an introduction, the growth of magnet school programs, implementation of magnet schools and magnet programs, federal support for magnet programs, nonmagnet schools and programs of choice, summary of findings and directions for further research. Appendices A-C include study samples, data, and detailed tables as well as the survey instruments. A glossary is also included. (Contains 15 rezerences.) (JPT) *********************************************************************** * Reproductions supplied by EDRS are the best that can be made * * from the original document. * *********************************************************************** Educational Imiovation in Multiracial Contexts: The Growth of Magnet Schools in American tducation ( ontract No 1 C90043001 *4"*? U,S. DEPARTMENT Of EDUCATION Office of Educational Research and tmprorarnent EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 14/f°fis document has been reproduced as recetvol from the person or organization onthnating 0 ;knot changes have been mad* to unprove reproduction Quality Points ot vow of opinions Stated in this doeth mint do not necessarily represent offiCial OERI position or policy Prerare'd f Or the U 1.erariffleht ot I ducanon under ()whir. t merican Institutes for Research: Palo Alto, California U (-; DEPARTMENT OF EDUCATION 411111 OFFICE OF THE UNDER SIVRIEAR) A Educational Innovation in Multiracial Contexts: The Growth of Magnet Schools in American Education Lauri Steel, AIR Roger Levine, AM Contract No. LC90043001 Prepared for the U.S. Department of Education under contract by: American Institutes for Research, Palo Alto, California 1994
The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide, and the mechanisms underlying the development of HCC remain to be elucidated. Forkhead box N3 (FOXN3) is an important member of the FOX family of transcription factors that plays an essential role in several cancers but has not been investigated in HCC. In this study, we demonstrate that FOXN3 is downregulated in human primary HCC tissues compared with their matched adjacent liver tissues. Functional tests of FOXN3 demonstrated that FOXN3 inhibits the proliferation of HCC cells in vitro and in vivo. Additionally, FOXN3 repressed the mRNA and protein expression of E2F5, a reported potential oncogene, by inhibiting the promoter activity of E2F5. Collectively, our findings indicate that FOXN3 functions as a tumor suppressor in HCC by downregulating the expression of E2F5.
Weighted ADMM for Fast Decentralized Network Optimization

In this paper, we propose a weighted alternating direction method of multipliers (ADMM) to solve the consensus optimization problem over a decentralized network. In the proposed algorithm, every node holds its local objective function, exchanges its current iterate with a subset of neighbors, carries on local computation, and eventually reaches an optimal and consensual solution that minimizes the summation of the local objective functions. Compared with the conventional ADMM that is popular in decentralized network optimization, the weighted ADMM is able to reduce the communication cost spent in the optimization process through tuning the weight matrices, which assign beliefs on the neighboring iterates. We first prove convergence and establish linear convergence rate of the weighted ADMM. Second, we maximize the derived convergence speed and obtain the best weight matrices on a given topology. Third, observing that exchanging information with all the neighbors is expensive, we maximize the convergence speed while limit the number of communication arcs. This strategy finds a subset of arcs within the underlying topology to fulfill the optimization task while leads to a favorable tradeoff between the number of iterations and the communication cost per iteration. Numerical experiments demonstrate advantages of the weighted ADMM over its conventional counterpart in expediting the convergence speed and reducing the communication cost.
Evaluation of Immunogenicity and Protective Efficacy Elicited by Mycobacterium bovis BCG Overexpressing Ag85A Protein against Mycobacterium tuberculosis Aerosol Infection

Mycobacterium bovis bacillus Calmette-Guérin (BCG) is currently the only vaccine available for preventing tuberculosis (TB), however, BCG has varying success in preventing pulmonary TB. In this study, a recombinant BCG (rBCG::Ag85A) strain overexpressing the immunodominant Ag85A antigen was constructed, and its immunogenicity and protective efficacy were evaluated. Our results indicated that the Ag85A protein was successfully overexpressed in rBCG::Ag85A, and the Ag85A peptide–MHC complexes on draining lymph node dendritic cells of C57BL/6 mice infected with rBCG::Ag85A were detectable 4 h post-infection. The C57BL/6 mice infected with this strain had stronger antigen-specific interferon-gamma (IFN-γ) responses and higher antibody titers than those immunized with BCG, and the protective experiments showed that rBCG::Ag85A can enhance protection against Mycobacterium tuberculosis (M. tuberculosis) H37Rv infection compared to the BCG vaccine alone. Our results demonstrate the potential of rBCG::Ag85A as a candidate vaccine against TB.