Miracle-dz/UniFAR-FTUs huggingface dataset:
The revised Temperament and Character Inventory: normative data by sex and age from a Spanish normal randomized sample

Objectives. The psychometric properties regarding sex and age for the revised version of the Temperament and Character Inventory (TCI-R) and its derived short version, the Temperament and Character Inventory (TCI-140), were evaluated with a randomized sample from the community. Methods. A randomized sample of 367 normal adult subjects from a Spanish municipality, who were representative of the general population based on sex and age, participated in the current study. Descriptive statistics and internal consistency according to α coefficient were obtained for all of the dimensions and facets. T-tests and univariate analyses of variance, followed by Bonferroni tests, were conducted to compare the distributions of the TCI-R dimension scores by age and sex. Results. On both the TCI-R and TCI-140, women had higher scores for Harm Avoidance, Reward Dependence and Cooperativeness than men, whereas men had higher scores for Persistence. Age correlated negatively with Novelty Seeking, Reward Dependence and Cooperativeness and positively with Harm Avoidance and Self-transcendence. Young subjects between 18 and 35 years had higher scores than older subjects in NS and RD. Subjects between 51 and 77 years scored higher in both HA and ST. The alphas for the dimensions were between 0.74 and 0.87 for the TCI-R and between 0.63 and 0.83 for the TCI-140. Conclusion. Results, which were obtained with a randomized sample, suggest that there are specific distributions of personality traits by sex and age. Overall, both the TCI-R and the abbreviated TCI-140 were reliable in the ‘good-to-excellent’ range. A strength of the current study is the representativeness of the sample.
Lameness Affects Cow Feeding But Not Rumination Behavior as Characterized from Sensor Data

Using automatic sensor data, this is the first study to characterize individual cow feeding and rumination behavior simultaneously as affected by lameness. A group of mixed-parity, lactating Holstein cows were loose-housed with free access to 24 cubicles and 12 automatic feed stations. Cows were milked three times/day. Fresh feed was delivered once daily. During 24 days with effectively 22 days of data, 13,908 feed station visits and 7,697 rumination events obtained from neck-mounted accelerometers on 16 cows were analyzed. During the same period, cows were locomotion scored on four occasions and categorized as lame (n = 9) or not lame (n = 7) throughout the study. Rumination time, number of rumination events, feeding time, feeding frequency, feeding rate, feed intake, and milk yield were calculated per day, and coefficients of variation were used to estimate variation between and within cows. Based on daily sums, using each characteristic as response, the effects of lameness and stage of lactation were tested in a mixed model. With rumination time as response, each of the four feeding characteristics, milk yield, and lameness were tested in a second mixed model. On a visit basis, effects of feeding duration, lameness, and milk yield on feed intake were tested in a third mixed model. Overall, intra-individual variation was <15% and inter-individual variation was up to 50%. Lameness introduced more inter-individual variation in feeding characteristics (26–50%) compared to non-lame cows (17–29%). Lameness decreased daily feeding time and daily feeding frequency, but increased daily feeding rate. Interestingly, lameness did not affect daily rumination behaviors, fresh matter intake, or milk yield. On a visit basis, a high feeding rate was associated with a higher feed intake, a relationship that was exacerbated in the lame cows. In conclusion, cows can be characterized in particular by their feeding behavior, and lame cows differ from their non-lame pen-mates in terms of fewer feed station visits, faster eating, less time spent feeding, and more variable feeding behavior. Further, daily rumination time was slightly negatively associated with feeding rate, a relationship which calls for more research to quantify rumination efficiency relative to feeding rate.
Experience Affects Recruitment of New Neurons But Not Adult Neuron Number

It is not known whether the addition of new neurons to the high vocal center (HVC) of juvenile zebra finches permits vocal learning or is the consequence of it. To tease apart these two, we performed surgery on 26-d-old juveniles. The operations were removal of both cochleae and unilateral or bilateral denervation of the syrinx. Ability to imitate a tutor song was little affected by unilateral syringeal denervation but was severely hindered by bilateral denervation or deafening. Recruitment of new HVC neurons was studied by injecting BrdU, a cell birth marker, on post-hatching days 61–65 and killing the animals 30 d later. Deafening or bilateral denervation did not alter the number of BrdU-labeled neurons in HVC, but unilateral denervation nearly doubled this number in the intact side. This doubling was transient, was blocked by deafening, and was not seen in birds that received BrdU injections earlier or later in vocal ontogeny. The adult number of HVC neurons was not affected by any of our surgical procedures. Apparently experience does not affect the total number of neurons in adult HVC, but some kinds of experience can, during narrowly defined times, influence the recruitment of new HVC neurons.
EFFECTS OF PRIOR ALTERATION IN NUCLEIC ACID AND PROTEIN METABOLISM ON SUBSEQUENT MACROMOLECULAR SYNTHESIS BY IRRADIATED BACTERIA

A previous communication (Billen, 1959a) described the alteration of the killing effect of X rays on Escherichia coli resulting from prior unbalanced growth. The possibility that the treatments by which the synthesis of protein, deoxyribonucleic acid (DNA), and ribonucleic acid (RNA) could be separated, would be reflected in altered postirradiation synthesis was next investigated. A preliminary report (Billen, 1959b) suggested that the DNA synthesizing mechanism of bacteria, like that of animal cells, was composed of a radiosensitive and radioresistant system. These results plus the data presented here show that postirradiation synthesis of nucleic acids is markedly influenced by prior alteration in the macromolecular constituents of the organism.
Twitter-Based EFL Pronunciation Instruction.

This paper looks at the use of Twitter as a language teaching/learning tool. It describes the results of a study aimed at testing Twitter’s effectiveness for pronunciation teaching. The purpose of the study was to determine whether Twitter can foster online participation and whether it may have a positive effect on the pronunciation of a number of words commonly mispronounced by EFL students. The study was carried out with students from a Language School in Spain. The students were sent a number of tweets on a daily basis, each of them featuring the pronunciation of a word considered to be difficult given unusual sound-spelling correspondences, lexical stress or the presence of silent letters. The results show that the instruction had a beneficial effect on the students’ pronunciation of the target words and that participants were actively engaged during the study. Implications of the results for the teaching of English pronunciation and the use of Twitter in language teaching are also offered. Language(s) Learned in this Study: English
Staple versus Locking Compression Plate Fixation after Lateral Closing Wedge High Tibial Osteotomy

Purpose. To compare the results of staple versus locking compression plate fixation after closing wedge high tibial osteotomy. Methods. A group of 23 patients (24 knees) who underwent box high tibial osteotomy and staple fixation was compared with another group of 19 patients (22 knees) who underwent a similar procedure but with locking compression plate fixation. Both groups were followed up for 3 years. The range of movement, Hospital for Special Surgery (HSS) Knee Score, time to full weight bearing, incidence of delayed union, femorotibial angle, and stage of osteoarthritis were compared. Results. At 6 months after the operation, the median HSS score and the proportion of patients with excellent or good scores were significantly higher in the locking compression plate than the staple fixation group (76 vs 62, p=0.003; 75% vs 42%, p=0.0354), but not at one and 3 years. The range of movement was significantly greater in the locking compression plate fixation group in the short term (6 weeks, 3 and 6 months), but not after one year. The median time to full weight bearing was significantly shorter in the locking compression plate fixation group (86 vs 116 days, p<0.001). There were fewer delayed unions in the locking compression plate fixation group but not significantly (1 vs 5, p=0.198), possibly because of the small numbers involved. There was no difference, within the limits of measurement error, in the femorotibial angle or correction loss between the 2 groups. Conclusion. Locking compression plate fixation obviates the use of plaster casts, enables early mobilisation and bone union, and reduces the numbers with delayed union and the time to full weight bearing. Longer-term studies are needed to evaluate its effect on revarisation and arthropathy.
Cryptic Species? Patterns of Maternal and Paternal Gene Flow in Eight Neotropical Bats

Levels of sequence divergence at mitochondrial loci are frequently used in phylogeographic analysis and species delimitation though single marker systems cannot assess bi-parental gene flow. In this investigation I compare the phylogeographic patterns revealed through the maternally inherited mitochondrial COI region and the paternally inherited 7th intron region of the Dby gene on the Y-chromosome in eight common Neotropical bat species. These species are diverse and include members of two families from the feeding guilds of sanguivores, nectarivores, frugivores, carnivores and insectivores. In each case, the currently recognized taxon is comprised of distinct, substantially divergent intraspecific mitochondrial lineages suggesting cryptic species complexes. In Chrotopterus auritus, and Saccopteryx bilineata I observed congruent patterns of divergence in both genetic regions suggesting a cessation of gene flow between intraspecific groups. This evidence supports the existence of cryptic species complexes which meet the criteria of the genetic species concept. In Glossophaga soricina two intraspecific groups with largely sympatric South American ranges show evidence for incomplete lineage sorting or frequent hybridization while a third group with a Central American distribution appears to diverge congruently at both loci suggesting speciation. Within Desmodus rotundus and Trachops cirrhosus the paternally inherited region was monomorphic and thus does not support or refute the potential for cryptic speciation. In Uroderma bilobatum, Micronycteris megalotis and Platyrrhinus helleri the gene regions show conflicting patterns of divergence and I cannot exclude ongoing gene flow between intraspecific groups. This analysis provides a comprehensive comparison across taxa and employs both maternally and paternally inherited gene regions to validate patterns of gene flow. I present evidence for previously unrecognized species meeting the criteria of the genetic species concept but demonstrate that estimates of mitochondrial diversity alone do not accurately represent gene flow in these species and that contact/hybrid zones must be explored to evaluate reproductive isolation.
Expression of schistosomal cathepsin l1 in Escherichia coli and evaluation of its protective capacity in an animal challenge

Schistosomes utilize proteinases to accomplish several activities such as tissue penetration, tissue digestion and evasion of host immune responses. Cathepsin L is a cysteine proteinase of the papain superfamily detected in their gut lumen which indicates that this enzyme contributes to the proteolysis of ingested hemoglobin. Due to the roles played in the schistosome biology, proteolytic enzymes are considered potential targets for developing and guiding antischistosomal therapies. In the present work, the cathepsin L1 cDNA coding of Schistosoma mansoni was cloned into the pAE vector that provides high-level expression of heterologous proteins in Escherichia coli. The recombinant protein was expressed as inclusion bodies, purified under denaturing conditions through nickel-charged chromatography and used for experimental animal vaccination. ELISA was performed with the pooled sera. Although this protein was shown to be immunogenic, mice immunized with three doses of recombinant protein plus aluminum hydroxide as adjuvant were not protected against S. mansoni infection.
Working Memory Training for Adults With ADHD

Objective: The aim of this study was to examine the effects of Cogmed training on working memory in adults with ADHD, including the generalization of effects to nonverbal reasoning, executive function in daily life, and ADHD symptoms. Method: Adults of ages 18 to 63 with ADHD were randomly assigned to an experimental group that received the working memory training or to a placebo group that received a low-intensity comparison version of the training. Results: participants in the experimental group showed greater improvement in verbal and visuospatial working memory capacity. Effects persisted 6 months after intervention completion. However, effects did not generalize elsewhere. Conclusion: The results challenge the claims made by Cogmed to the effect that the program is effective in treating attention problems and improving performance in daily life over the long term in adults with ADHD.
Centre De Referència En Economia Analítica Barcelona Economics Working Paper Series Working Paper Nº 158 on Information and Competition in Private Value Auctions on Information and Competition in Private Value Auctions

How much information does an auctioneer want bidders to have in a private value environment? We address this question using a novel approach to ordering information structures based on the property that in private value settings more information leads to a more disperse distribution of buyers' updated expected valuations. We define the class of precision criteria following this approach and different notions of dispersion, and relate them to existing criteria of informativeness. Using supermodular precision, we obtain three results: (1) a more precise information structure yields a more efficient allocation; (2) the auctioneer provides less than the efficient level of information since more information increases bidder informational rents; (3) there is a strategic complementarity between information and competition, so that both the socially efficient and the auctioneer's optimal choice of precision increase with the number of bidders, and both converge as the number of bidders goes to infinity. ‡ Part of this work was done while J-J Ganuza was visiting CEMFI. He thanks them for their hospitality. We specially like to thank Marco Ottaviani for his most insightful and useful comments on different drafts of this paper. We also wish to thank Jonathan Levin for helping us understand some of the subtleties of different notions of information, and David K. Levine and Bryan Ellickson for their suggestions on how best to present our ideas.
Validation of the use of firearms for euthanising stranded cetaceans

Efforts to euthanise stranded cetaceans remain highly variable in their outcomes, with few field tested operational procedures available. This study sought to validate the efficacy of using modern firearms technology to euthanise small (<6m length) stranded cetaceans. Post-mortem evidence was gathered from the standardised shooting of cetacean cadavers (n = 10), representing six species, using . 30 caliber (7.62mm) firearms and blunt solid copper-alloy non-deforming projectiles, in southwestern Australia. The six species studied were Risso’s dolphin, common dolphin, bottlenosed dolphin, pygmy sperm whale, Cuvier’s beaked whale, and humpback whale. Post-mortem data revealed that 100% of bullet wound tracts fully penetrated the skulls of shot animals, with associated indirect skull fracturing, secondary bone missiles and brain parenchyma laceration. The results suggest that appropriate firearms technology is fully capable of inducing instantaneous fatal pathology to the central nervous system of these species. In comparison to alternative methods for the euthanasia of stranded cetaceans, the use of firearms is associated with superior animal welfare outcomes, public safety levels and accessibility. This paper provides a template for the safe, humane and repeatable use of this technique to euthanise <6m length stranded cetaceans.
An Empirical Evaluation of a Probabilistic RF Signature for WLAN Location Fingerprinting

Localization for indoor environments has gained considerable attention over the last decade. The most popular technique is based on location fingerprinting using received signal strength (RSS) mainly due to the fact that it exploits the available wireless infrastructure and that RSS fingerprints are readily available using different wireless standards (IEEE 802.11, etc.). This simplicity however incurs a cost in accuracy and researchers focus on improving the performance from a pattern recognition perspective. Recently improvement in performance has been demonstrated using physical layer channel-based fingerprints such as the Channel Transfer Function (CTF) and Channel Impulse Response (CIR) at a cost of increased storage and computation requirements. In this paper we experimentally evaluate the performance of a probabilistic physical layer fingerprint that is based on entropy of the magnitude and phase of the CTF. We will show through extensive frequency domain channel measurements in an indoor office environment that entropy can be a practical alternative to RSS fingerprinting; where it shares the latter's simplicity of structure (scalar) but outperforms RSS and complex CIR fingerprints. We further investigate the impact of realistic channel and system impairments such as small-scale fading (Doppler), Signal-to-noise ratio (SNR) and interference on the performance of the proposed fingerprint signature.
Starvation-Induced Effects on Bacterial Surface Characteristics

Changes in bacterial surface hydrophobicity, charge, and degree of irreversible binding to glass surfaces of seven marine isolates were followed during starvation. The degree of hydrophobicity was measured by hydrophobic interaction chromatography and by two-phase separation in a hexadecane-water system, whereas changes in charge were measured by electrostatic interaction chromatography. All isolates underwent the starvation-induced responses of fragmentation, which is defined as division without growth, and continuous size reduction, which results in populations with increased numbers of smaller cells. The latter process was also responsible for a significant proportion of the total drop in cell volume; this was observed by noting the biovolume (the average cell multiplied by the number of bacteria) of a population after various times of starvation. Four strains exhibited increases in both hydrophobicity and irreversible binding, initiated after different starvation times. The most hydrophilic and most hydrophobic isolates both showed a small increase in the degree of irreversible binding after only 5 h, followed by a small decrease after 22 h. Their hydrophobicity remained constant, however, throughout the entire starvation period. On the other hand, one strain, EF190, increased its hydrophobicity after 5 h of starvation, although the degree of irreversible binding remained constant. Charge effects could not be generally related to the increase in irreversible binding. Scanning electron micrographs showed a large increase in surface roughness throughout the starvation period for all strains that showed marked changes in physicochemical characteristics.
Auxin Biosynthesis: Are the Indole-3-Acetic Acid and Phenylacetic Acid Biosynthesis Pathways Mirror Images?1[OPEN]

Phenylacetic acid biosynthesis appears to proceed similarly to that of indole-3-acetic acid, but the enzymes responsible for these pathways are not identical. The biosynthesis of the main auxin in plants (indole-3-acetic acid [IAA]) has been elucidated recently and is thought to involve the sequential conversion of Trp to indole-3-pyruvic acid to IAA. However, the pathway leading to a less well studied auxin, phenylacetic acid (PAA), remains unclear. Here, we present evidence from metabolism experiments that PAA is synthesized from the amino acid Phe, via phenylpyruvate. In pea (Pisum sativum), the reverse reaction, phenylpyruvate to Phe, is also demonstrated. However, despite similarities between the pathways leading to IAA and PAA, evidence from mutants in pea and maize (Zea mays) indicate that IAA biosynthetic enzymes are not the main enzymes for PAA biosynthesis. Instead, we identified a putative aromatic aminotransferase (PsArAT) from pea that may function in the PAA synthesis pathway.
A Scalable Architecture For High-Throughput Regular-Expression Pattern Matching

We present and evaluate an architecture for high-throughput pattern matching of regular expressions. Our approach matches multiple patterns concurrently, responds rapidly to changes in the pattern set, and is well suited for synthesis in an ASIC or FPGA. Our approach is based on a new and easily pipelined state-machine representation that uses encoding and compression techniques to improve density. We have written a compiler that translates a set of regular expressions and optimizes their deployment in the structures used by our architecture. We analyze our approach in terms of its throughput, density, and efficiency. We present experimental results from an implementation in a commodity FPGA, showing better throughput and density than the best known approaches
Evaluation of Prompted Annotation of Activity Data Recorded from a Smart Phone

In this paper we discuss the design and evaluation of a mobile based tool to collect activity data on a large scale. The current approach, based on an existing activity recognition module, recognizes class transitions from a set of specific activities (for example walking and running) to the standing still activity. Once this transition is detected the system prompts the user to provide a label for their previous activity. This label, along with the raw sensor data, is then stored locally prior to being uploaded to cloud storage. The system was evaluated by ten users. Three evaluation protocols were used, including a structured, semi-structured and free living protocol. Results indicate that the mobile application could be used to allow the user to provide accurate ground truth labels for their activity data. Similarities of up to 100% where observed when comparing the user prompted labels and those from an observer during structured lab based experiments. Further work will examine data segmentation and personalization issues in order to refine the system.