Miracle-dz/UniFAR-FTUs huggingface dataset:
Performance evaluation in PAPR and ICI for ISIM-OFDM systems

Interleaved subcarrier-index modulation for orthogonal frequency division multiplexing (ISIM-OFDM) is a recently developed technique, where the indices of OFDM subcarriers are utilized to convey information bits and subcarrier-level interleaving scheme is considered. For the conventional OFDM system, the main drawbacks lie in the high peak-to-average power ratio (PAPR) at transmitter and its sensitiveness to inter-carrier interference (ICI) in a highly mobile environment. In this paper, the performance evaluation in PAPR and ICI for ISIM-OFDM system is presented. Simulation results show that ISIM-OFDM system can efficiently reduce the PAPR and is more robust to ICI compared with traditional OFDM system.
A Statistical Approach to Prediction of Empty Categories in Hindi Dependency Treebank

In this paper we use statistical dependency parsing techniques to detect NULL or Empty categories in the Hindi sentences. We have currently worked on Hindi dependency treebank which is released as part of COLINGMTPIL 2012 Workshop. Earlier Rule based approaches are employed to detect Empty heads for Hindi language but statistical learning for automatic prediction is not explored. In this approach we used a technique of introducing complex labels into the data to predict Empty categories in sentences. We have also discussed about shortcomings and difficulties in this approach and evaluated the performance of this approach on different Empty categories.
Comparison of a Material Point Method and a Galerkin Meshfree Method for the Simulation of Cohesive-Frictional Materials

The simulation of large deformation problems, involving complex history-dependent constitutive laws, is of paramount importance in several engineering fields. Particular attention has to be paid to the choice of a suitable numerical technique such that reliable results can be obtained. In this paper, a Material Point Method (MPM) and a Galerkin Meshfree Method (GMM) are presented and verified against classical benchmarks in solid mechanics. The aim is to demonstrate the good behavior of the methods in the simulation of cohesive-frictional materials, both in static and dynamic regimes and in problems dealing with large deformations. The vast majority of MPM techniques in the literatrue are based on some sort of explicit time integration. The techniques proposed in the current work, on the contrary, are based on implicit approaches, which can also be easily adapted to the simulation of static cases. The two methods are presented so as to highlight the similarities to rather than the differences from “standard” Updated Lagrangian (UL) approaches commonly employed by the Finite Elements (FE) community. Although both methods are able to give a good prediction, it is observed that, under very large deformation of the medium, GMM lacks robustness due to its meshfree natrue, which makes the definition of the meshless shape functions more difficult and expensive than in MPM. On the other hand, the mesh-based MPM is demonstrated to be more robust and reliable for extremely large deformation cases.
On the Separability of Stochastic Geometric Objects, with Applications

In this paper, we study the linear separability problem for stochastic geometric objects under the well-known unipoint/multipoint uncertainty models. Let $S=S_R \cup S_B$ be a given set of stochastic bichromatic points, and define $n = \min\{|S_R|, |S_B|\}$ and $N = \max\{|S_R|, |S_B|\}$. We show that the separable-probability (SP) of $S$ can be computed in $O(nN^{d-1})$ time for $d \geq 3$ and $O(\min\{nN \log N, N^2\})$ time for $d=2$, while the expected separation-margin (ESM) of $S$ can be computed in $O(nN^{d})$ time for $d \geq 2$. In addition, we give an $\Omega(nN^{d-1})$ witness-based lower bound for computing SP, which implies the optimality of our algorithm among all those in this category. Also, a hardness result for computing ESM is given to show the difficulty of further improving our algorithm. As an extension, we generalize the same problems from points to general geometric objects, i.e., polytopes and/or balls, and extend our algorithms to solve the generalized SP and ESM problems in $O(nN^{d})$ and $O(nN^{d+1})$ time, respectively. Finally, we present some applications of our algorithms to stochastic convex-hull related problems.
Divergent acceptance of change in a public health organization

Purpose – The purpose of this paper is to explore the way in which health professional (HP)‐based subcultures interpret reform‐based changes.Design/methodology/approach – A three‐phase study is carried out using thematic analysis to examine data from semi‐structured interviews held with 19 HPs to examine their responses to change. Also, responses from 639 self‐completion questionnaires and focus group interviews with 44 women provide insight into the influence of the change on end‐users of the service.Findings – This study extends previous work through inductive examination of the interpretations of two subcultures, which reveal that acceptance of the strategic change objective is subsequently undermined by divergence in the way members of the subcultures interpret and seek to enact change – a divergent acceptance.Research limitations/implications – The findings result from a single case‐study healthcare setting. Future studies can extend the research to other settings.Practical implications – The insight.
More than a Metaphor: Assessing the Historical Legacy of Resource Dependence and its Contemporary Promise as a Theory of Environmental Complexity

At its inception, resource dependence (RD) held the promise to become a robustly developed theoretical perspective. However, behind an ever-growing citation count, scholars—including one of its key architects—have asserted that RD no longer inspires much substantive research and now serves as little more than an appealing metaphor about organizations [Pfeffer, J. (2003). Introduction to the classic edition. In J. Pfeffer & G.R. Salancik, The external control of organizations: A resource dependence perspective (classic edition). New York: Harper & Row]. A systematic analysis of RD's uses in the management literature lends some credence to this assessment. However, our analysis also shows a perspective that has been broadly influential and well-supported in applications that cross multiple empirical domains. Moreover, this impact has been achieved despite the widespread neglect of what is arguably RD's most distinctive insight; namely that an organization's external environment is composed of other organiza.
Studying the Effects of Reproductive Hormones and Bacterial Vaginosis on the Glycome of Lavage Samples from the Cervicovaginal Cavity

The cervicovaginal fluid (CVF) coating the vaginal epithelium is an important immunological mediator, providing a barrier to infection. Glycosylation of CVF proteins, such as mucins, IgG and S-IgA, plays a critical role in their immunological functions. Although multiple factors, such as hormones and microflora, may influence glycosylation of the CVF, few studies have examined their impact on this important immunological fluid. Herein we analyzed the glycosylation of cervicovaginal lavage (CVL) samples collected from 165 women under different hormonal conditions including: (1) no contraceptive, post-menopausal, (2) no contraceptive, days 1-14 of the menstrual cycle, (3) no contraceptive, days 15-28 of the menstrual cycle, (4) combined-oral contraceptive pills for at least 6 months, (5) depo-medroxyprogesterone acetate (Depo-Provera) injections for at least 6 months, (6) levonorgestrel IUD for at least 1 month. Glycomic profiling was obtained using our lectin microarray system, a rapid method to analyze carbohydrate composition. Although some small effects were observed due to hormone levels, the major influence on the glycome was the presence of an altered bacterial cohort due to bacterial vaginosis (BV). Compared to normal women, samples from women with BV contained lower levels of sialic acid and high-mannose glycans in their CVL. The change in high mannose levels was unexpected and may be related to the increased risk of HIV-infection observed in women with BV, as high mannose receptors are a viral entry pathway. Changes in the glycome were also observed with hormonal contraceptive use, in a contraceptive-dependent manner. Overall, microflora had a greater impact on the glycome than hormonal levels, and both of these effects should be more closely examined in future studies given the importance of glycans in the innate immune system.
EGF, TGF-α and EGFR expression in human preimplantation embryos

Epidermal growth factor (EGF) and transforming growth factor alpha (TGF-α) through their common receptor, epidermal growth factor receptor (EGFR) are known to enhance mitogenesis, development and implantation in several species. In the mouse, co-culture of grouped embryos in microdrops increases the cell number and proportion developing to the blastocyst stage. A similar effect is observed with culture of single embryos in medium supplemented with EGF or TGF-α highlighting their embryotrophic effects. To study the role of EGF, TGF-α and EGFR in early human development, two methods applicable for analysis of expression at the single embryo level have been employed. In the first method, reverse transcription-polymerase chain reaction has been used to examine the presence of transcripts. Following reverse transcription, strategically designed nested primers, optimised for specificity, were used for amplification from the cDNA equivalent of a single embryo. The products were then verified by restriction enzyme digestion and sequence analysis. In the second method, immunocytochemistry has been used to colocalise the expressed proteins. Individual embryos were paraffin embedded and serial sectioned, allowing adjacent sections to be examined with different antibodies and controls. Monoclonal TGF-α and polyclonal EGF and EGFR primary antibodies were used. Staining was performed by peroxidase-conjugated avidin-biotin immunocytochemistry with the appropriate controls. The combination of these two methods can potentially be used for simultaneous analysis of several growth factors and/or their receptors in the same human embryos. Transcripts for EGF, TGF-α and EGFR were detected in unfertilized oocytes and embryos between 8-cell and blastocyst stages on day 3 to 6 post-insemination. Similarly, at the protein level, all three were detected in unfertilized oocytes and throughout preimplantation development to day 8. At the blastocyst stage, expression was observed in both the trophectoderm and inner cell mass but decreased in more advanced blastocysts except in the polar trophectoderm and inner cell mass. This pattern of expression contrasts with the murine and bovine species in which TGF-α and EGFR but not EGF are expressed at preimplantation stages. The concurrent co-expression of these growth factors and their receptor suggests a role for autocrine stimulation in preimplantation development. In the human, reduced protein levels of EGF, TGF-α and EGFR in advanced blastocysts may reflect a switch to dependence on paracrine stimulation. This may explain the inadequacy of simple culture media to maintain the development of human embryos at later stages and the benefits of co-culture with somatic cells. The continuous expression of EGF, TGF-α and EGFR in the polar trophectoderm may be significant for implantation.
Feasibility of detection and intervention for alcohol-related liver disease in the community: the Alcohol and Liver Disease Detection study (ALDDeS).

BACKGROUND In the past 15 years mortality rates from liver disease have doubled in the UK. Brief alcohol advice is cost effective, but clinically meaningful reductions in alcohol consumption only occur in around 1 in 10 individuals. AIM To provide evidence that detecting early liver disease in the community is feasible, practical, and that feedback of liver risk can increase the proportion of subjects reducing alcohol consumption. DESIGN AND SETTING A community feasibility study in nine general practice sites in Hampshire. METHOD Hazardous and harmful drinkers were identified by WHO AUDIT questionnaire and offered screening for liver fibrosis. RESULTS In total, 4630 individuals responded, of whom 1128 (24%) hazardous or harmful drinkers were offered a liver fibrosis check using the Southampton Traffic Light (STL) test; 393 (38%) attended and test results were returned by post. The STL has a low threshold for liver fibrosis with 45 (11%) red, 157 (40%) amber, and 191 (49%) green results. Follow-up AUDIT data was obtained for 303/393 (77%) and 76/153 (50%) subjects with evidence of liver damage reduced drinking by at least one AUDIT category (harmful to hazardous, or hazardous to low risk) compared with 52/150 (35%, P<0.011) subjects without this evidence; in the subset of harmful drinkers patterns (AUDIT >15), 22/34 (65%) of STL positives, reduced drinking compared with 10/29 (35%, P<0.017) STL negatives. CONCLUSION Detection of liver disease in the community is feasible, and feedback of liver risk may reduce harmful drinking.
Islam and Muslims in the Mind of America: Influences on the Making of U. S. Policy

This essay examines the ways in which the U.S. public, media, interest groups, and foreign policy elite, including Congress, influence the making of American policy toward political Islam. After analyzing the focal historical, cultural, and current political developments that inform Americans9 attitudes on Islamic resurgence, the paper argues that contemporary security and strategic considerations, not just culture and ideology, account for America9s preoccupation with Islamism.
Increased osteoblast adhesion on titanium-coated hydroxylapatite that forms CaTiO3.

CaTiO(3) is a strong candidate to form at the interface between hydroxylapatite (HA) and titanium implants during many coating procedures. However, few studies have compared the cytocompatibility properties of CaTiO(3) to HA pertinent for bone-cell function. For this reason, the objective of the present in vitro study was to determine the ability of bone-forming cells (osteoblasts) to adhere on titanium coated with HA that resulted in the formation of CaTiO(3). To accomplish the formation of CaTiO(3), titanium was coated on HA discs and annealed either under air or a N(2)+H(2) environment. Materials were characterized by X-ray diffraction (XRD), Rutherford backscattering spectroscopy (RBS), and atomic force microscopy (AFM). These characterization techniques demonstrated the formation of a nanometer rough CaTiO(3) layer as a consequence of interactions between HA and titanium during coating conditions. Results from cytocompatibility tests revealed increased osteoblast adhesion on materials that contained CaTiO(3) compared to both pure HA and uncoated titanium. The greatest osteoblast adhesion was observed on titanium-coated HA annealed under air conditions. Because adhesion is a crucial prerequisite to subsequent functions of osteoblasts (such as the deposition of calcium containing mineral), the present in vitro results imply that orthopedic coatings that form CaTiO(3) could increase osseointegration with juxtaposed bone needed for increased implant efficacy.
Underperformance or ‘getting it right’? Constructions of gender and achievement in the Australian inquiry into boys’ education

The underachievement of boys has been a focus of intense concern in Australia for over 15 years. Historical analyses suggest that male students’ poor performance has traditionally been attributed to factors external to boys themselves (methods, teachers, texts), deflecting attention from the relationship between masculinity construction and successful engagement with school. This paper turns the focus back, addressing the ways in which gender itself was constructed within hearings held for the Australian Parliamentary Inquiry into Boys’ Education. Discursive analysis demonstrates that witnesses to the Inquiry drew upon a series of gender binaries in representing male and female students, and accounting for their relative attainment. These binaries worked to associate masculinity with ‘authentic’ learning, such that the success of male students was naturalised even in the absence of achievement. Conversely, the association of femininity and ‘inauthentic learning’ worked to undermine female students’ demonstrated success. The role of these binaries in the reproduction of a paradoxical relationship between gender and achievement is discussed.
Dispelling the Myths Behind Pediatric Patch Testing—Experience from Our Tertiary Care Patch Testing Centers

Abstract: Allergic contact dermatitis is now known to be a common problem in pediatric populations, accounting for up to 20% of all dermatitis seen in children. Seminal studies conducted over the past decade have demonstrated a prevalence rate in the range of 25% to 60% of children referred for epicutaneous patch testing. This patch test procedure is generally accepted as the gold standardin vivo technique to diagnose allergic contact dermatitis. However, the overwhelming majority of research studies to date have been conducted on adult populations. Increasingly, pediatric patients are undergoing patch test procedures with techniques that have been standardized and optimized almost exclusively in adults. With this article, we hope to emphasize common misconceptions and pitfalls encountered with this approach. In addition, we hope to stimulate research interest in this field so as to determine the optimum patch test conditions and techniques for children.
EXPERIMENTAL STUDY OF LASER-INDUCED MELTING IN TWO-DIMENSIONAL COLLOIDS

We study the phase behavior of a charged two-dimensional colloidal system in the presence of a periodic light field composed of two interfering laser beams. Above a certain light intensity, the light field initiates a liquid-solid transition. This effect is known as light-induced freezing. When the light field is increased above a critical value, however, the induced crystal is predicted to melt into a modulated liquid again. In this paper we report the first direct experimental observation of this reentrance phenomenon. [S0031-9007(98)07130-0]
Role stressors, task-oriented norm and job satisfaction: a longitudinal study

In line with the Job Demands-Resources Model (JD-R) this study analyzes the role of task-oriented norm (job resource) and role stressors (job demands) to predict job satisfaction over time. In order to test this effect, a sample was gathered in a manufacturing setting at two different times. Hierarchical regression analysis tests the principal and the interaction effects of role stressors (role conflict and role overload) and task-oriented norm to predict job satisfaction. Results confirm the negative effect of role conflict at Time 1 on job satisfaction at Time 2 showing the relevance of setting priorities to neutralize the negative effect of this stressor. Moreover, these results show the interaction between task overload (Time 1) and task-oriented norm (Time 1) on job satisfaction (Time 2) after working together for more than one year as a permanent group. Discussion is focused on the structural work context and within group implications of these findings in real working settings.
Role of Group V Phospholipase A2 in Zymosan-induced Eicosanoid Generation and Vascular Permeability Revealed by Targeted Gene Disruption*

Conclusions regarding the contribution of low molecular weight secretory phospholipase A2 (sPLA2) enzymes in eicosanoid generation have relied on data obtained from transfected cells or the use of inhibitors that fail to discriminate between individual members of the large family of mammalian sPLA2 enzymes. To elucidate the role of group V sPLA2, we used targeted gene disruption to generate mice lacking this enzyme. Zymosan-induced generation of leukotriene C4 and prostaglandin E2 was attenuated ∼50% in peritoneal macrophages from group V sPLA2-null mice compared with macrophages from wild-type littermates. Furthermore, the early phase of plasma exudation in response to intraperitoneal injection of zymosan and the accompanying in vivo generation of cysteinyl leukotrienes were markedly attenuated in group V sPLA2-null mice compared with wild-type controls. These data provide clear evidence of a role for group V sPLA2 in regulating eicosanoid generation in response to an acute innate stimulus of the immune response both in vitro and in vivo, suggesting a role for this enzyme in innate immunity.
Governance, leadership, and management in federations of schools

In England, federations are defined as groups of schools that have a formal agreement to collaborate with the aim of raising achievement and promoting inclusion and innovation. This paper presents a number of findings from the case study strand of a 3-year study investigating the impact of 37 federations (see Lindsay et al., 2007). Maximum variation sampling (Maykutt & Morehouse, 1994) was used to select 10 case study federations. Key stakeholders were interviewed during 3 rounds of field visits. Documentary evidence from each case provided important contextual information and provided a source of triangulation. Within- and between-case analyses from case studies (Miles & Huberman, 1994) highlighted a number of key themes, patterns, and trends that have implications for the development of collaborative strategies attempting to restructure and reculture schools and their communities. This paper explores issues of leadership, management, and governance in federations. Findings suggest localised ownership and control of the process within the context of interdependent relationships have supported the development of a range of models of governance, leadership, and management in school federations.
Effect of Efavirenz on the Pharmacokinetics of Simvastatin, Atorvastatin, and Pravastatin: Results of AIDS Clinical Trials Group 5108 Study

Efavirenz (EFV) is associated with hyperlipidemia when used in combination with other antiretroviral drugs. EFV is a mixed inducer/inhibitor of cytochrome P450 (CYP) 3A4 isozyme and may interact with hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors that are primarily metabolized via CYP3A4. To assess the drug-drug interaction of EFV used in combination with simvastatin (SIM), atorvastatin (ATR), or pravastatin (PRA), an open-label trial was conducted in 52 healthy adult HIV-seronegative subjects across AIDS Clinical Trials Group sites in the United States. Subjects received 40 mg of SIM, 10 mg of ATR, or 40 mg of PRA daily on days 0 through 3 and days 15 through 18. EFV was administered daily at a dose of 600 mg on days 4 through 18. SIM, ATR, and PRA concentrations were determined before and after EFV, and EFV concentrations were determined before and after statins. EFV reduced SIM acid exposure (area under the curve at 0 to 24 hours [AUC0-24h]) by 58% (Wilcoxon signed rank test, P = 0.003) and active HMG-CoA reductase inhibitory activity by 60% (P < 0.001). EFV reduced ATR exposure by 43% (P < 0.001) and the total active ATR exposure by 34% (P = 0.005). EFV administration resulted in a 40% decrease in PRA exposure (P = 0.005). SIM, ATR, and PRA had no effect on non-steady-state EFV concentrations. In conclusion, EFV, when administered with SIM, ATR, or PRA, can result in significant induction of statin metabolism. The reduced inhibition of HMG-CoA reductase activity during coadministration of EFV may result in diminished antilipid efficacy at usual doses of SIM, ATR, and PRA.