Miracle-dz/UniFAR-FTUs huggingface dataset:
Policy traps for third parties in two-party systems: the Australian case

Despite a steady erosion of the major parties' share of the vote in Australia, minor parties have been unable to attract more than 15 per cent of the vote. Employing a variation of Katz and Mair's cartel party thesis, this paper argues that the major parties have an advantage in defining and limiting power sharing arrangements and setting and reacting to the policy agenda. They can act together to deny a third-party oxygen, or can deflect criticism of controversial policies onto the third party. A critical appraisal of seven cases of government formation involving the Australian Greens and Australian Democrats, along with two case studies of legislative negotiation shows that the electoral backlash is often borne by the minor parties.
The Economics of Modern Manufacturing: Technology, Strategy, and Organization

Manufacturing is undergoing a revolution. The mass production model is being replaced by a vision of a flexible multiproduct firm that emphasizes quality and speedy response to market conditions while utilizing technologically advanced equipment and new forms of organization. The authors' optimizing model of the firm generates many of the observed patterns that mark modern manufacturing. Central to the authors' results is a method of handling optimization and comparative statics problems that requires neither differentiability nor convexity. Copyright 1990 by American Economic Association.
Dividend and debt policies of family controlled firms

Purpose - This paper's aim is to examine whether board independence influences debt and dividend policies of family controlled firms. Design/methodology/approach - The paper examines panel data on a sample of Australian publicly-listed firms over the period 2000-2005 using panel (random effects) regression. Findings - Empirical test demonstrates that family controlled firms appear to have higher levels of leverage and dividend payout ratios than their non-family counterparts. More importantly, the result indicates that the positive impact of family control on dividend policy is due to the higher proportion of independent directors on family boards. This underlines the significant role that independent directors play in influencing firm's dividend policies, especially for family controlled firms. The result also supports the notion that independent directors and dividends are complementary government mechanisms. This paper, however, finds little evidence that board independence moderates the relationship between family control and debt. Research limitations/implications - While not all family firms are the same, this research treats them as a homogeneous grouping (i.e. firms are delineated into family versus non-family). The fact that family firms are difficult to identify and define (reflected in the diversity of definitions in the literature) may also affect the validity of studies of family business. For policy makers, the finding could serve to justify initiatives to encourage more independent directors on boards, especially in family controlled firms. Originality/value - This paper provides evidence about the relationship between board independence, dividends and debt from a country with higher levels of private benefits of control, strong legal shareholder protection but less significant role of external governance mechanisms compared to the USA.
Biphasic calcium phosphate loading on polycaprolactone/poly(lacto-co-glycolic acid) membranes for improved tensile strength, in vitro biocompatibility, and in vivo tissue regeneration

Electrospun polycaprolactone and poly(lacto-co-glycolide) membranes were loaded with biphasic calcium phosphate powder to facilitate osteoconductivity. Different concentrations of biphasic calcium phosphate powder were added to the polymer solution, and successful loading was confirmed by X-ray diffraction analysis, transmission electron microscope, and scanning electron microscope with energy-dispersive spectroscopy visualization. The effect of the added biphasic calcium phosphate on the polymer membrane was investigated in terms of the material’s tensile strength and strain, in vitro cytocompatibility, and in vivo tissue regeneration. It was observed that the tensile strength of the membranes increased with the addition of the biphasic calcium phosphate powder. Immersion in simulated body fluid solution for seven days leads to the formation of apatite-like deposits in the fibers, which further improved the mechanical stability. Moreover, proliferation and adhesion of osteoblast-like cells were more apparent upon the addition of the biphasic calcium phosphate powder as seen with the increasing cell density from (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and micrographs from scanning electron microscope and confocal microscopy. Sample membranes were also implanted to investigate the membrane’s ability to regenerate bone in a rat calvarium. Histological staining and micro-CT histomorphometric analyses showed neo-bone formation in the implanted rat skull.
South Asian entrepreneurship in Great Britain: factors influencing growth

Analyses the factors influencing South Asian entrepreneurial expansion in Great Britain and the validity of conventional wisdom which attributes its success to cultural factors. It suggests that entrepreneurial growth depends positively on educational attainment, personal savings invested at start‐up, hard work in the initial stages, and the delegation of responsibilities to non‐family members. Further analysis indicates that later entrants into business gained relevant prior work experience and focused on serving non‐Asian customers, which may have contributed towards their success. The pursuit of constant product and technological improvement and employee training have also influenced growth. There is strong evidence that entrepreneurs with larger‐sized businesses have developed international linkages and focused on one key business area.
Rapid Induction of Histone Hyperacetylation and Cellular Differentiation in Human Breast Tumor Cell Lines following Degradation of Histone Deacetylase-1*

Quinidine inhibits proliferation and promotes cellular differentiation in human breast tumor epithelial cells. Previously we showed quinidine arrested MCF-7 cells in G1 phase of the cell cycle and led to a G1 to G0 transition followed by apoptotic cell death. The present experiments demonstrated that MCF-7, MCF-7ras, T47D, MDA-MB-231, and MDA-MB-435 cells transiently differentiate before undergoing apoptosis in response to quinidine. The cells accumulated lipid droplets, and the cytokeratin 18 cytoskeleton was reorganized. Hyperacetylated histone H4 appeared within 2 h of the addition of quinidine to the medium, and levels were maximal by 24 h. Quinidine-treated MCF-7 cells showed elevated p21 WAF1 , hypophosphorylation and suppression of retinoblastoma protein, and down-regulation of cyclin D1, similar to the cell cycle response observed with cells induced to differentiate by histone deacetylase inhibitors, trichostatin A, and trapoxin. Quinidine did not show evidence for direct inhibition of histone deacetylase enzymatic activity in vitro. HDAC1 was undetectable in MCF-7 cells 30 min after addition of quinidine to the growth medium. The proteasome inhibitors MG-132 and lactacystin completely protected HDAC1 from the action of quinidine. We conclude that quinidine is a breast tumor cell differentiating agent that causes the loss of HDAC1 via a proteasomal sensitive mechanism.
Investigating market value and intellectual capital for S&P 500

Purpose – The purpose of this study is to examine and answer the following research questions: how does the US electronic industry perform from an intellectual capital (IC) perspective? What is the relationship between IC and company market value in the US electronic industry? This study investigated the relationship between IC and company market value in the US Standard & Poor's 500 (US S&P 500) publicly traded electronic companies from 1996 to 2005.Design/methodology/approach – The Ohlson model theory was reviewed and to form the research models. Secondary data were retrieved from S&P's Compustat for quantitative analysis.Findings – When applying multiple regression technique to the research hypotheses, there emerges a positive relationship between IC and market value of the company. Apparently, US electronic companies are knowledge intensive and utilize IC to create their market capitalization.Originality/value – This is one of the first empirical researches that quantitatively examine the market value.
An Empirical Analysis of Latitude of Price Acceptance in Consumer Package Goods

Scanner panel data analyses for sweetened and unsweetened drink categories (with four brands in each) support the presence of a region of price insensitivity around a reference price. The analyses also suggest that consumers with higher average reference price have a wider latitude of price acceptance. Consumers with a higher frequency of purchase (i.e., shorter average interpurchase time interval) are found to have a narrower latitude of price acceptance, because they are more aware of the range of price distributions. Finally, consumers with a higher average brand loyalty have a wider latitude of price acceptance, demonstrating greater tolerance of price fluctuations. Copyright 1994 by the University of Chicago.
COLLABORATIVE CAPACITY AND STRATEGIES IN AREA-BASED INITIATIVES

Despite considerable evaluator investment in examining partnership activity in UK public policy initiatives, little attention has been paid to the role of strategy in supporting the generation and harnessing of the resources necessary to collaborate effectively. This paper focuses on one of the first New Labour initiatives - Health Action Zones (HAZ) - and draws on national evaluation findings to delineate local strategies, assess their application in practice and reflect on their contribution to collaborative action. The paper argues that even within nationally constrained policy initiatives there is sufficient flexibility for local actors to select strategies to steer collaborative effort, but these strategies are informed by their operating context and are liable to change in response to experience and changes in context. In addition, the evaluation findings suggest that effective strategies are those which harness collaborative capacity across a range of dimensions. The paper concludes by identifying implications for theory, policy and evaluation. © Blackwell Publishing Ltd. 2006.
An analysis of hippocampal spatio-temporal representations using a Bayesian algorithm for neural spike train decoding

Neural spike train decoding algorithms are important tools for characterizing how ensembles of neurons represent biological signals. We present a Bayesian neural spike train decoding algorithm based on a point process model of individual neurons, a linear stochastic state-space model of the biological signal, and a temporal latency parameter. The latency parameter represents the temporal lead or lag between the biological signal and the ensemble spiking activity. We use the algorithm to study whether the representation of position by the ensemble spiking activity of pyramidal neurons in the CA1 region of the rat hippocampus is more consistent with prospective coding, i.e., future position, or retrospective coding, past position. Using 44 simultaneously recorded neurons and an ensemble delay latency of 400 ms, the median decoding error was 5.1 cm during 10 min of foraging in an open circular environment. The true coverage probability for the algorithm's 0.95 confidence regions was 0.71. These results illustrate how the Bayesian neural spike train decoding paradigm may be used to investigate spatio-temporal representations of position by an ensemble of hippocampal neurons.
Relationships among industry environment, diversification motivations and corporate performance

Purpose – This paper aims to examine empirically the relationships among industry environment, diversification motivations and corporate performance for a sample of Taiwanese automobile enterprises.Design/methodology/approach – A 55‐item survey questionnaire was developed to obtain the responses from companies in the automobile industry in Taiwan. Independent sample t‐test and χ2 tests were employed to confirm the homogeneity between the respondents and non‐respondents by firm's characteristics, including by industry, number of employees, and capital.Findings – The results suggest that industry environment has positive and significant impact on diversification motivations, and has positive but not significant impact on corporate performance. Diversification motivations has positive and significant impact on corporate performance. The results also indicate that firms of higher capital amounts have greater influence on diversification motivations and corporate performance, firms of publicly listed have grea.
Resistance in Pediatric Patients Experiencing Virologic Failure With First-line and Second-line Antiretroviral Therapy

We examined HIV-1 resistance in children failing first-line and second-line antiretroviral therapy in South Africa, all with clade C virus. Those exposed to full-dose ritonavir had multiple protease resistance mutations. Nineteen percent had wild-type virus. Appropriate antiretroviral therapy sequencing in sub-Saharan African children is essential for prolong treatment options.
Predicting energy expenditure from accelerometry counts in adolescent girls.

PURPOSE Calibration of accelerometer counts against oxygen consumption to predict energy expenditure has not been conducted in middle school girls. We concurrently assessed energy expenditure and accelerometer counts during physical activities on adolescent girls to develop an equation to predict energy expenditure. METHODS Seventy-four girls aged 13-14 yr performed 10 activities while wearing an Actigraph accelerometer and a portable metabolic measurement unit (Cosmed K4b2). The activities were resting, watching television, playing a computer game, sweeping, walking 2.5 and 3.5 mph, performing step aerobics, shooting a basketball, climbing stairs, and running 5 mph. Height and weight were also assessed. Mixed-model regression was used to develop an equation to predict energy expenditure (EE) (kJ.min(-1)) from accelerometer counts. RESULTS Age (mean [SD] = 14 yr [0.34]) and body-weight-adjusted correlations of accelerometer counts with EE (kJ.min(-1)) for individual activities ranged from -0.14 to 0.59. Higher intensity activities with vertical motion were best correlated. A regression model that explained 85% of the variance of EE was developed: [EE (kJ.min(-1)) = 7.6628 + 0.1462 [(Actigraph counts per minute - 3000)/100] + 0.2371 (body weight in kilograms) - 0.00216 [(Actigraph counts per minute - 3000)/100](2) + 0.004077 [((Actigraph counts per minute - 3000)/100) x (body weight in kilograms)]. The MCCC = 0.85, with a standard error of estimate = 5.61 kJ.min(-1). CONCLUSIONS We developed a prediction equation for kilojoules per minute of energy expenditure from Actigraph accelerometer counts. This equation may be most useful for predicting energy expenditure in groups of adolescent girls over a period of time that will include activities of broad-ranging intensity, and may be useful to intervention researchers interested in objective measures of physical activity.
Towards a Java Subtyping Operad

The subtyping relation in Java exhibits self-similarity. The self-similarity in Java subtyping is interesting and intricate due to the existence of wildcard types and, accordingly, the existence of three subtyping rules for generic types: covariant subtyping, contravariant subtyping and invariant subtyping. Supporting bounded type variables adds to the complexity of the subtyping relation in Java and other similar generic nominally-typed OO languages such as C# and Scala. In this paper we explore defining an operad to model the construction of the subtyping relation in Java and similar languages. Operads, from category theory, are frequently used to model self-similar phenomena. The Java subtyping operad, we hope, will shed more light on understanding the type systems of generic nominally-typed OO languages.
Analysis of New Product Diffusion Using a Four-Segment Trial-Repeat Model

A four segment trial-repeat model is developed to model sales of a frequently purchased product in the early stage of the product's life cycle. The model can be calibrated using aggregate data alone. Two versions of the model, one emphasizing the competitive aspect of marketing communications and another emphasizing the informative aspect, are estimated from data on 21 newly launched pharmaceutical products. The model provides valuable diagnostics such as an early estimate of the long-run market share of the new product, a decomposition of total sales into trial sales due to marketing activities, trial sales due to word-of-mouth, and repeat sales, the changing composition of the trial market and repeat market over time, and the time when the trial market is expected to be saturated. In addition, the effectiveness of the entrant's marketing efforts, word-of-mouth communication, and buyers' trial experience are analyzed with the model. A cross-sectional analysis based on the empirical estimation results of our model reveals interesting insights into product introduction strategies. We find that: 1 the effectiveness of the firms' communication activities on trial is related mainly to product quality attributes and market growth whereas that of word-of-mouth is associated with product class characteristics and market competitiveness, and 2 the effect of product trial on repeat purchases is related mainly to product quality attributes and various market characteristics such as size, growth, competitiveness, and familiarity.
Reliability analysis of MTJ-based functional module for neuromorphic computing

The power and reliability issues of today's memories limit the improvements attained by their implementation in scaled technology nodes. Several emergent memory technologies attempt to address the technical constraints of today's memories, amongst which, one of the most promising solutions is the Spin-Transfer-Torque Magnetic Random Access Memories (STT-MRAMs). One of the great advantages of the emerging memories is that they favor increasing system complexity and performance. New applications and computation paradigms, such as neuromorphic computing, unfeasible a few years back due to technological limitations, can take profit from this technology. Intensive research has been conducted recently related to magnetic device physics and its implementation as dedicated hardware for neuromorphic computing, however, little work has been conducted to evaluate the reliability of such circuits. In this paper we investigate the effect of meaningful MTJ reliability issues on the behavior of an MTJ-based Spiking Neural Network.
Transesophageal Doppler Measurement of Renal Arterial Blood Flow Velocities and Indices in Children

BACKGROUND: Doppler-derived renal blood flow indices have been used to assess renal pathologies. However, transesophageal ultrasonography (TEE) has not been previously used to assess these renal variables in pediatric patients. In this study, we (a) assessed whether TEE allows adequate visualization of the renal parenchyma and renal artery, and (b) evaluated the concordance of TEE Doppler-derived renal blood flow measurements/indices compared with a standard transabdominal renal ultrasound (TAU) in children. METHODS: This prospective cohort study enrolled 28 healthy children between the ages of 1 and 17 years without known renal dysfunction who were undergoing atrial septal defect device closure in the cardiac catheterization laboratory. TEE was used to obtain Doppler renal artery blood velocities (peak systolic velocity, end-diastolic velocity, mean diastolic velocity, resistive index, and pulsatility index), and these values were compared with measurements obtained by TAU. Concordance correlation coefficient (CCC) was used to determine clinically significant agreement between the 2 methods. The Bland-Altman plots were used to determine whether these 2 methods agree sufficiently to be used interchangeably. Statistical significance was accepted at P ⩽ 0.05. RESULTS: Obtaining 2-dimensional images of kidney parenchyma and Doppler-derived measurements using TEE in children is feasible. There was statistically significant agreement between the 2 methods for all measurements. The CCC between the 2 imaging techniques was 0.91 for the pulsatility index and 0.66 for the resistive index. These coefficients were sensitive to outliers. When the highest and lowest data points were removed from the analysis, the CCC between the 2 imaging techniques was 0.62 for the pulsatility index and 0.50 for the resistive index. The 95% confidence interval (CI) for pulsatility index was 0.35 to 0.98 and for resistive index was 0.21 to 0.89. The Bland-Altman plots indicate good agreement between the 2 methods; for the pulsatility index, the limits of agreement were −0.80 to 0.53. The correlation of the size of the measurement and the mean difference in methods (−0.14; 95% CI = −0.28, 0.01) was not statistically significant (r = 0.31, P = 0.17). For the resistive index, the limits of agreement were −0.22 to 0.12. The correlation of the size of the measurement and the mean difference in methods (−0.05; 95% CI = −0.09, −0.01) was not statistically significant (r = 0.10, P = 0.65). CONCLUSION: This study confirms the feasibility of obtaining 2-dimensional images of kidney parenchyma and Doppler-derived measurements using TEE in children. Angle-independent TEE Doppler-derived indices show significant concordance with those derived by TAU. Further studies are required to assess whether this correlation holds true in the presence of renal pathology. This technique has the potential to help modulate intraoperative interventions based on their impact on renal variables and may prove helpful in the perioperative period for children at risk of acute kidney injury.
Increase in skin autofluorescence and release of heart-type fatty acid binding protein in plasma predicts mortality of hemodialysis patients.

Advanced glycation end-products (AGEs) are uremic toxins that accumulate progressively in hemodialysis (HD) patients. The aim of this study was to assess the 1-year increase in skin autofluorescence (ΔAF), a measure of AGEs accumulation and plasma markers, as predictors of mortality in HD patients. One hundred sixty-nine HD patients were enrolled in this study. Skin autofluorescence was measured twice, 1 year apart using an AGE Reader (DiagnOptics Technologies BV, Groningen, The Netherlands). Besides routine blood chemistry, additional plasma markers including superoxide dismutase, myeloperoxydase, intercellular adhesion molecule 1 (ICAM-1), C-reactive protein (hs-CRP), heart-type fatty acid binding protein (H-FABP), and von Willebrand factor were measured at baseline. The mortality of HD patients was followed for 36 months. Skin autofluorescence values of the HD patients at the two time points were significantly higher (P < 0.001) than those of healthy subjects of the same age. Mean 1-year ΔAF of HD patients was 0.16 ± 0.06, which was around seven- to ninefold higher than 1-year ΔAF in healthy subjects. Multivariate Cox regression showed that age, hypertension, 1-year ΔAF, hs-CRP, ICAM-1, and H-FABP were independent predictors of overall mortality. Hypertension, 1-year ΔAF, hs-CRP, and H-FABP were also independent predictors of cardiovascular mortality. One-year ΔAF and plasma H-FABP, used separately and in combination, are strong predictors of overall and cardiovascular mortality in HD patients.