Miracle-dz/UniFAR-FTUs huggingface dataset:
transformed B-lymphocytes Theileria microdomains permits Src kinase-dependent proliferation of Constitutive exclusion of Csk from Hck-positive membrane

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Analysis of Rural Quality of Life and Health: A Spatial Approach

This article examines the relationship between quality of life, health, and several socioeconomic variables. It draws on survey data from a random sample of more than 2,000 residents in 21 counties in West Virginia and spatial data generated by geocoding survey respondents' addresses and hospital locations. The empirical results are consistent with the theoretical predictions and indicate, for instance, that quality-of-life satisfaction increases with income and education but decreases with unemployment. Also, the results support the notion that inferences drawn regarding substantive issues often change when spatial dependence is taken into account.
Real diversity or just another mask: An ethnomethodological study of authentic ethnicity of African-American community college administrators

At the turn of the 20 century, W.E. B. DuBois theorized that African Americans, then referred to as Negroes, are forced to live a life of “double-consciousness” for survival. He asserts that navigating the thin line between the cultural expectations of White mainstream America, and being one’s authentic self, creates immeasurable stress and contempt. This ethnomethodological inquiry of racial and cultural dynamics of the community college seeks to understand the intentional strategies of seven African American community college presidents and chancellors, as they balance their authentic selves and the cultural mainstream of the community and the college. This study leads to a conscious integration of ideas and strategies that may supplement or even counter traditional ideologies, thereby reconstructing an institutional culture that encourages the growth of a truly diverse population of administrators, faculty, staff, and students.
Enterotomy and Mortality Rates of Laparoscopic Incisional and Ventral Hernia Repair: a Review of the Literature

Laparoscopic incisional and ventral hernia (LVIH) repair is becoming more popular throughout the world. Although individual series have presented their own information, few data have been collected to identify the risk of the most serious complication, enterotomy. A literature review has identified this to occur in 1.78% of patients who undergo this procedure. Large bowel injury represents only 8.3% of these injuries. Eighty-two percent of the time, these injuries will be recognized and repaired. In the majority of published series in which this occurred, the hernia repair was completed with a laparoscopically placed prosthesis, as only 43% were converted to the open procedure. Complications related to this approach are infrequent. The mortality rate of this operation was noted to be 0.05%. However, if an enterotomy occurred, it increased to 2.8%. A recognized enterotomy was associated with a mortality rate of 1.7%, but an unrecognized enterotomy had a rate of 7.7%. Careful technique and close inspection of the intestine at the completion of the adhesiolysis and the herniorrhaphy is recommended. If the hernia repair proceeds as planned following repair of enterotomy, continuation of antibiotics and the placement of an antimicrobial impregnated prosthesis are recommended. More study is necessary before firm recommendations can be made, as the majority of these events are most likely unreported. Safety concerns may require postponement of the hernia repair if an enterotomy occurs.
Contribution of major bacterial groups to bacterial biomass production (thymidine and leucine incorporation) in the Delaware estuary

Assimilation of 3HH‐thymidine and 3HH‐leucine was examined at the single‐cell level using a combination of microautoradiography and fluorescent in situ hybridization (Micro‐FISH) to determine the contribution of various bacterial groups to bacterial production in aquatic systems. All of the major phylogenetic groups of bacteria examined along the salinity gradient of the Delaware estuary, including alpha‐, beta‐, and gamma‐proteobacteria and Cytophaga‐like bacteria, assimilated 3H‐thymidine and 3H‐leucine. However, groups differed substantially in their contribution to the assimilation of these compounds. Alpha‐proteobacteria were the dominant substrate‐active bacteria at salinities of . 9 PSU, whereas beta‐proteobacteria were more important in freshwater. At all salinities, Cytophaga‐like bacteria comprised the second most important group, and gamma‐proteobacteria were overall the least important. Bacterial abundance explained about half of the variation in 3H‐thymidine and 3H‐leucine assimilation by the major bacterial groups. The sizes of silver grains of active bacteria indicate no difference in singlecell activity for the bacterial groups, suggesting that the average growth rates of the groups we examined were similar. However, activity per cell was distributed differently in the phylogenetic groups. Our study suggests that estimates of bacterial production measured using 3H‐thymidine and 3H‐leucine include bacteria in all of the major phylogenetic groups found in aquatic systems and that growth rates within bacterial groups vary substantially.
Problems with parallel analysis in data sets with oblique simple structure

Parallel analysis, one of the most promising methods to determine the number of principal components or factors to retain (Velicer, Eaton, & Fava, 2000), has been shown to underestimate the number of components to retain when the first eigenvalue is large (Turner, 1998). In order to further explore the potential problems with parallel analysis, orthogonal and oblique 4-, 8-, and 12-component solutions with four different degrees of simple structure were computed for simulated data. Since the first eigenvalue of the oblique solutions was generally large, parallel analysis was expected to underestimate the number of components to retain in these solutions. This was confirmed in the present simulation study. Even in solutions with pronounced oblique simple structure, parallel analysis tended to result in underextraction for the 8- and 12-component solutions. Thus, one should be aware of the possibility of underextractions when parallel analysis is used with data yielding components or factors with oblique simple structure.
Cross-country convergence in income inequality

Neoclassical models imply convergence of the entire distribution, not just the mean income levels. In this paper, we test for convergence in income inequality across countries. We compile extensive data on gini indices over a period of 25 years. Convergence in inequality is tested separately for developed and developing countries, using cross-section and panel data. We estimate a dynamic panel model using the GMM estimator and as well as an efficient OLS estimator for a smaller sample. Our results indicate that during 1980 and 2005 inequality converged across countries. The speed of convergence in gini indices is faster than the conventional 2% per year speed of convergence in per capita income. Developed countries appear to have converged faster than developing countries. The result of convergence in inequality is robust across different time horizons, data sources and estimation methods.
Are Solar Acoustic Modes Correlated

We have studied the statistical properties of the energy of individual acoustic modes, extracted from 310 days of GOLF data near the solar minimum. The exponential distribution of the energy of each mode is clearly seen. The modes are found to be uncorrelated with a +-0.6 % accuracy, thus supporting the hypothesis of stochastic excitation by the solar convection. Nevertheless, the same analysis performed on the same modes just before the solar maximum, using IPHIR data, rejects the hypothesis of no correlation at a 99.3 % confidence level. A simple model suggests that 31.3 +-9.4 % of the energy of each mode is coherent among the modes studied in IPHIR data, correponding to a mean correlation of 10.7 +-5.9 %.
Large Scale Online Kernel Learning

In this paper, we present a new framework for large scale online kernel learning, making kernel methods efficient and scalable for large-scale online learning applications. Unlike the regular budget online kernel learning scheme that usually uses some budget maintenance strategies to bound the number of support vectors, our framework explores a completely different approach of kernel functional approximation techniques to make the subsequent online learning task efficient and scalable. Specifically, we present two different online kernel machine learning algorithms: (i) Fourier Online Gradient Descent (FOGD) algorithm that applies the random Fourier features for approximating kernel functions; and (ii) Nystrom Online Gradient Descent (NOGD) algorithm that applies the Nystrom method to approximate large kernel matrices. We explore these two approaches to tackle three online learning tasks: binary classification, multi-class classification, and regression. The encouraging results of our experiments on large-scale datasets validate the effectiveness and efficiency of the proposed algorithms, making them potentially more practical than the family of existing budget online kernel learning approaches.
Identification of Estrogen-Related Genes in Breast Cancer: The Malaysian Context

Estrogen receptor (ER) status is an important indicator used to predict hormone responsiveness and survival rate of breast cancer patients. Breast cancer patients with estrogen receptor positive (ER+) tumors are more likely to benefit from endocrine therapies and have better prognosis than those with estrogen receptor negative (ER-) tumors. Approximately 30% of the patients with ER+ phenotype do not benefit from anti-estrogen therapies. This circumstance suggests that additional biomarkers are needed to predict and improve the treatment strategies in breast cancer patients. We analyzed 28 ER+ and 18 ER- tumors to evaluate their gene expression patterns. We identified 180 differentially expressed genes in ER+ compared to the ER- group at 99% confidence interval level. Out of the 180 genes, 79 and 94 genes were determined respectively as positive and negative significant genes in Significance Analysis of Microarray (SAM). Eleven out of the 79 significant positive genes were more than two (>2) fold change. The differentially expressed genes identified in the ER+ group included CADM4, CD151, GATA3, Wnt2, PGR, TFF1 and TFF3. We randomly selected two genes, namely CD151 and LPIN1 for verification by Taqman qRT-PCR. Our qRT-PCR result is reproducible and comparable with the microarray data. Our preliminary findings revealed potential estrogen-responsive genes such as CADM4, CD151 and GATA3, which might play a crucial role in ER+ breast cancer development and progression in the Malaysian population. More extensive studies are however needed to investigate the role of these genes in the carcinogenesis of estrogen related breast cancers.
Dystrophic microglia in the aging human brain

We have studied microglial morphology in the human cerebral cortex of two nondemented subjects using high‐resolution LN‐3 immunohistochemistry. Several abnormalities in microglial cytoplasmic structure, including deramification, spheroid formation, gnarling, and fragmentation of processes, were identified. These changes were determined to be different from the morphological changes that occur during microglial activation and they were designated collectively as microglial dystrophy. Quantitative evaluation of dystrophic changes in microglia revealed that these were much more prevalent in the older subject (68‐year‐old) than in the younger one (38‐year‐old). Thus, we conclude that microglial dystrophy is a sign of microglial cell senescence. We hypothesize that microglial senescence could be important for understanding age‐related declines in cognitive function. © 2003 Wiley‐Liss, Inc.
Implication of the CSR and cultural model features in Romanian energy sector

Energy has become a major factor in promoting and achieving a highly competitive economy during last couple of decades. The Romanian energy sector has passed through a massive reform process with divergent effects and restrictive implication both for industry and population. In this context it is very important that the major energy business players respect and follow the cultural model framework and their own CSR policies. The main aim of the paper is to analyze the implication of the CSR and cultural model features in Romanian energy sector.
Familiarity facilitates social learning of foraging behaviour in the guppy

Previous studies have shown that guppies, Poecilia reticulata, can learn the route to a food source by shoaling with knowledgeable conspecifics, and prefer to shoal with experienced foragers and familiar fish. We tested the hypothesis that guppies would learn more effectively from (1) familiar than unfamiliar demonstrators and (2) well-trained than poorly trained demonstrators. Demonstrator fish were given experience in swimming a route to a food source and then introduced into shoals of untrained observer guppies; the spread of this foraging skill was recorded over 15 trials. The demonstrators were either familiar or unfamiliar to the observers and either well trained or poorly trained. Observers performed significantly better when the demonstrators were familiar. The training of the demonstrators made no overall difference to the performance of naive observers. However, whilst observers in shoals exposed to well-trained demonstrators did better initially than those with poorly trained ones, the latter learned the route to the feeder faster. Our results suggest that familiarity may generate a form of directed social learning in guppy shoals, in which fish learn more effectively from familiar conspecifics. An analysis of who follows whom suggests that well-trained demonstrators can provide a ‘tip-off’ as to the location of the hole but poorly trained demonstrators were more likely to be followed. The results suggest that while observers are able to shoal with poorly trained demonstrators, well-trained demonstrators swim the maze route too quickly to be followed, but may attract attention to the maze route.
Telocytes in neuromuscular spindles

A new cell type named telocyte (TC) has recently been identified in various stromal tissues, including skeletal muscle interstitium. The aim of this study was to investigate by means of light (conventional and immunohistochemical procedures) and electron microscopy the presence of TCs in adult human neuromuscular spindles (NMSs) and lay the foundations for future research on their behaviour during human foetal development and in skeletal muscle pathology. A large number of TCs were observed in NMSs and were characterized ultrastructurally by very long, initially thin, moniliform prolongations (telopodes – Tps), in which thin segments (podomeres) alternated with dilations (podoms). TCs formed the innermost and (partially) the outermost layers of the external NMS capsule and the entire NMS internal capsule. In the latter, the Tps were organized in a dense network, which surrounded intrafusal striated muscle cells, nerve fibres and vessels, suggesting a passive and active role in controlling NMS activity, including their participation in cell‐to‐cell signalling. Immunohistochemically, TCs expressed vimentin, CD34 and occasionally c‐kit/CD117. In human foetus (22–23 weeks of gestational age), TCs and perineural cells formed a sheath, serving as an interconnection guide for the intrafusal structures. In pathological conditions, the number of CD34‐positive TCs increased in residual NMSs between infiltrative musculoaponeurotic fibromatosis and varied in NMSs surrounded by lymphocytic infiltrate in inflammatory myopathy. We conclude that TCs are numerous in NMSs (where striated muscle cells, nerves and vessels converge), which provide an ideal microanatomic structure for TC study.
Gender and policy in English education : schooling for girls 1902-1944

Part 1: Education, sex and gender education and equality gender and methodology policy, aims and intentions in education. Part 2 Schooling for girls - defining the aims: the aims of education the idea of the curriculum "woman" and femininity psychology, gender and femininity. Part 3 The Board of Education: the role of the Board structure and operation power and decision-making educational principles and gender debate practical decision-making the School Certificate and the Group IV controversy. Part 4 Teachers and other authorities: teachers or "mere ciphers"? Local Education Authorities. Part 5 The curriculum: curricular preconceptions curricular prescriptions. Appendices: Memorandum submitted by the NUWT to the Board of Education Departmental Committee on "The Teaching of Domestic Science in Public Elementary Schools, 1939" women's occupations recommendations of the Consultative Committee from the report on "Differentiation of the Curriculum for Boys and Girls Respectively in Secondary Schools".
A Multitrait-Multimethod Model for the Measurement of Sensitivity to Reward and Sensitivity to Punishment

Abstract. It was investigated whether sensitivity to reward and sensitivity to punishment as conceived in Gray's (1991) Reinforcement Sensitivity Theory could be measured by means of a multitrait-multimethod (MTMM) model containing method factors representing situational variance. On the basis of the similarities between sensitivity to reward and punishment with promotion- and prevention-orientation, as discussed in the organizational context, the situational contexts were mainly chosen from school and organization. A total of 347 German participants completed a 58-item questionnaire measuring sensitivity to reward and punishment in the context of the team, of supervisors/instructors, and consumption. Confirmatory factor analysis revealed a factor for sensitivity to reward, for sensitivity to punishment, and three situational context factors (team, supervisor/instructor, and consumption). Thus, the situational variance could be controlled by means of the MTMM design. Moreover, some relations of sensitivit.
MobiGUITAR - A Tool for Automated Model-Based Testing of Mobile Apps

As mobile devices become increasingly smarter and more powerful, so too must the engineering of their software. User-interface driven system testing of these devices is gaining popularity, with each vendor releasing some automation tool(s). We feel that these tools are inappropriate for amateur program- mers, an increasing fraction of the app developer population. We present MobiGUITAR for automated GUI-driven testing of Android apps. MobiGUITAR is based on observation, extraction, and abstraction of the run-time state of GUI widgets. The abstraction is a scalable state-machine model that, together with test coverage criteria, provides a way to automatically generate test cases. We apply MobiGUITAR to 4 open-source Android apps, automatically generate and execute 7,711 test cases, and report 10 new bugs. A number of bugs are "Android-specific," stemming from the event- and activity-driven nature of Android.
Essais sur les transferts internationaux des migrants: une approche macroéconomique

Cette these apporte quatre essais sur les transferts internationaux des migrants, en utilisant une approche macroeconomique. Le premier essai examine empiriquement, sur 14 pays d'Amerique Latine et des Caraibes, les determinants macroeconomiques des transferts des migrants. Les trois autres essais portent sur les effets macroeconomiques des transferts des migrants sur les economies des pays en developpement. Le deuxieme essai evalue quantitativement la contribution des chocs de transferts des migrants dans la fluctuation macroeconomique du Senegal, en utilisant un modele d'equilibre general dynamique stochastique. Le troisieme essai examine l'effet des transferts sur le taux de change reel en menant une etude empirique sur les pays de la zone Franc CFA. Finalement, le quatrieme essai etudie empiriquement l'effet des transferts des migrants sur la volatilite macroeconomique de 87 pays en developpement en mettant un accent particulier sur l'interaction entre les transferts et le developpement financier.
Everyday party politics: local volunteers and professional organizers in grassroots campaigns

4 Acknowledgements . 5 Preface . 6 Chapter 1: Introduction . 8 Chapter 2: Research Design . 32 Chapter 3: Organization . 65 Chapter 4: Learning.90 Chapter 5: Motives and Meaning.121 Chapter 6: Representation and Linkage.155 Chapter 7: Professional organizers and expert volunteers.180 Chapter 8: Conclusion . 205 Bibliography.222 Appendices.237
Beating thy Neighbor: Derby Effects in German Professional Soccer

Summary It is widely acknowledged that derbies between two teams from the same city or region catch more public attention than “normal” soccer matches. Terms such as “Old Firm” (Rangers vs. Celtic), “Merseyside” (Liverpool FC vs. Everton FC), “Superclásico” (Boca Juniors vs. River Plate), and “Revierderby” (Dortmund vs. Schalke) are well-known even to people outside their respective countries of origin. Using data from the German Bundesliga from 1999 to 2009, we test whether derbies differ from other soccer matches with respect to the number of goals scored by each team, match results, and referee evaluations. The results are very surprising given the enormous amount of public attention that derbies with their special character attract: we find that there are no significant differences between derbies and “normal” matches. Despite the importance of derbies for fans and the public, they turn out to be “normal” soccer matches in all other respects.
Quantifying Estimation Bias in Residential Appraisal

The purpose of this study was to empirically test the ability of residential appraisers to estimate market value of houses. Using a sample of over 500 appraisals made for corporate relocation firms, the appraisal estimates of market value were compared with the actual price that the house sold for subsequently. The results indicate that current appraisal methods produce unbiased estimates of market value. Additional empirical results are presented that show that seasonal factors and regional economic conditions significantly explain variation in appraisal error.
Dendritic cells are susceptible to infection with wild-type adenovirus, inducing a differentiation arrest in precursor cells and inducing a strong T-cell stimulation

Adenovirus infection after stem cell transplantation is a significant cause of morbidity and mortality, especially in children. A robust T-cell response induced by dendritic cells (DC) is crucial for clearing the virus, suggesting their pivotal role for the response to human adenoviruses (HAdV). Despite the widespread use of adenoviral vectors, the properties and kinetics of HAdV infection of DC have not been addressed yet. We show that a recent clinical HAdV, subgenus C/serotype 2 (strain BB2000-61), infects cells of the myeloid lineage. Infected DC produce early and late viral antigens and show an altered expression of surface markers. Infection of monocytes renders them refractory to differentiation into DC. Additionally, HAdV-infected DC are strong stimulators of CD8+ T cells. In summary, HAdV seems to manipulate the immune response by infection of DC and possibly uses the infection of monocytes as a means to escape recognition by T cells.