Miracle-dz/UniFAR-FTUs huggingface dataset:
Osteoprotegerin as a marker of cardiovascular risk in patients on peritoneal dialysis.

INTRODUCTION Arterial thickening contributes to elevated cardiovascular risk in patients on maintenance renal replacement therapy. The common carotid artery intima-media thickness (CCA-IMT) is an early atherosclerotic marker and may be used to assess the stratification of atherosclerotic advancement and resultant arterial calcification. OBJECTIVES The aim of the study was to evaluate the associations between atherosclerotic changes in the common carotid arteries expressed as the CCA-IMT and the body mass index (BMI), serum lipid levels, C‑reactive protein (CRP), and selected bone metabolism parameters including phosphorus, calcium, intact parathormone (iPTH), alkaline phosphatase, osteopontin, osteoprotegerin, osteocalcin, fetuin A, and fibroblast growth factor‑23 (FGF‑23) in patients treated with peritoneal dialysis. PATIENTS AND METHODS The study included 67 patients with chronic kidney disease (36 men and 31 women) aged 53 ±13 years (range, 19-75 years) treated with peritoneal dialysis for 30 ±24 months. The CCA‑IMT was assessed by ultrasonography using Acuson 128/10 XP. The BMI was calculated using the Quetelet formula. Serum lipid levels, phosphorus, calcium, iPTH, alkaline phosphatase, and CRP were measured using standard laboratory methods, while fetuin A, osteocalcin, osteoprotegerin, osteopontin, and FGF‑23 using commercial enzyme‑linked immunosorbent assay kits. RESULTS Positive correlations were observed between CCA-IMT and age (r = 0.54, P <0.0001), BMI (r = 0.39, P = 0.003), and osteoprotegerin (r = 0.38, P = 0.004). In a multiple regression analysis, age (r = 0.41, P = 0.01), osteocalcin (r = 0.34, P = 0.04), and log‑transformed osteoprotegerin values (r = 0.38, P = 0.02) remained independently associated with the CCA-IMT. The highest CCA‑IMT values (0.85 ±0.21) were observed in patients with osteoprotegerin concentrations in the upper tertile. Osteoprotegerin concentrations strongly and positively correlated with the duration of dialysis treatment (r = 0.55, P <0.0001). CONCLUSIONS The CCA‑IMT has been shown to be a reliable noninvasive measure of subclinical atherosclerosis and, therefore, of associated increased vascular risk. Elevated serum osteoprotegerin levels may be useful as a prognostic marker of cardiovascular risk in dialyzed patients.
Stuff You'd Never Think Of: Children Talk about Homelessness and How They'd Like to Be Supported

This article reports on research carried out with children who had experienced homelessness in the Australian Capital Territory (ACT), which involved taking a comprehensive and innovative qualitative methodology for engaging the children in the project. This article discusses what 'homelessness' means to children who have accompanied their parents during periods of homelessness. Although problematic, children reported that during periods of homelessness they felt connected and supported by their families and that their parents mitigated some of its negative affects. They believed that having lived through difficult times they and their families had developed an appreciation for life and a sense that they could overcome future challenges. Children's involvement in research such as this contributes to our knowledge about how children experience homelessness and having a home in important way.
KEEFEKTIFAN MODEL PENEMUAN TERBIMBING DAN COOPERATIVE LEARNING PADA PEMBELAJARAN MATEMATIKA

Tujuan penelitian ini adalah untuk (1) menemukan model pembelajaran yang menghasilkan prestasi belajar terbaik (2) menemukan kategori kreativitas siswa yang menghasilkan prestasi belajar terbaik (3) menemukan interaksi model pembelajaran dan kreativitas siswa yang menghasilkan prestasi belajar terbaik. Hasil belajar pada riset ini dibatasi pada topik bangun ruang sisi lengkung. Penelitian ini menggunakan desain kuasi eksperimen dengan menggunakan analisis varian dua jalur dengan ukuran sel berbeda. Populasi penelitian ini adalah siswa semester enam di SMP 4 kabupaten Wonogiri. Sampel diambil dengan teknik strafkasi dan kluster acak. Data dikumpulkan dengan dokumentasi, kuesioner, dan tes. Hasil penelitian menunjukkan (1) guided discovery model dan cooperative learning memberikan hasil yang tidak berbeda tetapi dampak terhadap hasil belajar siswa, keduanya lebih baik daripada model pembelajaran konvensional. (2) siswa yang memiliki kreativitas lebih dalam bidang matematika memiliki hasil belajar lebih baik dibandingkan dengan siswa yang memiliki kreativitas lebih rendah (3) pada level kreativitas tinggi, siswa memiliki hasil belajar lebih baik dengan menggunakan model pembelajaran guided discovery dibanding menggunakan model cooperative learning. Selanjutnya model cooperative learning menghasilkan hasil belajar siswa lebih baik daripada model pembelajaran konvensional.
Self-assessed dental health, oral health practices, and general health behaviors in Chinese urban adolescents

The objectives of this study were: to describe perceived dental health status and oral health-related knowledge, attitudes, and behavior in Chinese urban adolescents; to assess the associations of oral health variables with socio-economic status and school performance; and to analyse the relative effect of socio-behavioral risk factors on perceived dental health, perceived need for dental care, and experience of dental symptoms. A cross-sectional survey of 2662 adolescents was conducted in eight capital cities in China; the response rate was 92%. The study population was chosen by multistage cluster sampling and covered three age groups: 11, 13, and 15 years. Data on dental and general health were collected by self-administered questionnaires. Self-assessment of dental health of Chinese adolescents was generally good, only 12% of the students answered that their teeth were “poor” or “very poor”, and 9% claimed having “poor” or “very poor” gums. Eleven percent of participants said that other students made fun of their teeth; 24% of the respondents were dissatisfied with the appearance of their teeth, and 41% claimed that they had experienced toothache or symptoms during the previous 12 months. Positive attitudes towards dental care were found in all age groups; 67% of adolescents brushed their teeth at least twice a day and 48% of the students used fluoridated toothpaste. Only 26% of the students visited a dentist during the previous 12 months. In all, 6% of the adolescents had tried cigarette smoking at least once, while 41% reported having tasted alcohol drinks. Multivariate regression analyses showed that perceived dental health status and needs were associated with gender, age, unhealthy lifestyles, poor school performance, and socio-economic status. The establishment of school-based health promotion programs in China is urgently needed, and promotion of oral health lifestyles should be integrated with other general health actions.
L'externalisation dans les services documentation : Premiers résultats d'une enquête nationale

La pratique de l’externalisation dans les services documentation est une realite encore mal connue, alors qu’elle est souvent etudiee dans d’autres secteurs. Afin de reunir des donnees precises sur les pratiques actuelles dans le secteur de l’information-documentation, l’ADBS a lance fin 2002 une enquete nationale aupres de ses adherents. Cet article en presente les premiers resultats, organises selon trois des dimensions explorees par l’enquete : quelles sont les caracteristiques des services documentation qui externalisent ? Quelles sont les principales fonctions qu’ils sous-traitent ? Quelle est leur appreciation sur cette pratique : opportunite de recentrage ou menace sur leur existence meme ?
Comparison of AM1 and B3LYP‐DFT for Inhibition of MAO‐A by Phenylisopropylamines: A QSAR Study

The aim of this study is to provide an initial indication regarding the scope and limitations of some state‐of‐the‐art methods in computational chemistry, including semiempirical (AM1) and density functional theory (B3LYP), in the flip regression procedure applied to the inhibition of phenylisopropylamines. The results show that the models established based on the density functional theory‐B3LYP are better than that based on semiempirical method (AM1). It is demonstrated that electron‐rich ring systems and highest occupied molecular orbital levels tended to increase activity. In this contribution, it is shown that the orientation of nodes in their occupied π orbitals, and also the energies of these orbitals explain a further large portion of the variance in their inhibitory activity.
Smart Broadcast of Warning Messages in Vehicular Ad Hoc Networks

Broadcasting of safety messages is one of the fundamental services in vehicular ad hoc networks (VANETs). These services typically require to deliver the information to all vehicles traveling over a geographical area, with high reliability and low delay. In this document, we study the performance of a forwarding scheme and a channel access mechanism for improving the efficiency of message broadcasting in VANETs. The proposed channel access scheme is based on a spatial differentiation approach: vehicles that are about to rebroadcast the message access the channel with different priorities, depending on their distance from the last vehicle that retransmitted the message. We study the performance of the proposed solution by simulation and present some preliminary results.
Social Learning Theory

• Albert Bandura was the major motivator behind social learning theory. One of the main things that he was concerned with was how cognitive factors influence development, but he confined his approach to the behavioural tradition. Bandura called his theory a social cognitive theory. Like other behaviourists, Bandura believes that cognitive development alone cannot explain changes in behaviour in childhood and he believed that learning processes are primarily responsible for children's development. However, he felt quite strongly that the cognitive abilities of the child affect learning processes. This, he feels, is especially true of the more complex types of learning. So, how does Bandura handle the child's learning? Observational Learning • The problem, Bandura left, with classical and operant conditioning is that it has great difficulty explaining how it is that children acquire new behaviours simply by watching someone else and copying them. Also, a child does not have to be reinforced herself for the behaviour to be learned, it is enough for the child to see someone else being rewarded. Neither of these can be satisfactorily explained by a type of learning (like operant conditioning) that relies on the child experiencing the direct consequences of her actions. Bandura could explain this easily by proposing a different type of learning: observational learning. Bandura claimed that children's learning is heavily reliant on observation. Who do children observe and model themselves on? Initially parents and siblings and eventually friends, teachers, sporting heroes, TV characters. even cartoon characters! Just about anyone will do! So, Bandura would claim that the child who has seen her parents being kind and caring, giving to charity, caring for the environment, being kind to animals, will tend to be the same. However, the child who has seen problems being faced with violence, arguments occurring, wrongdoing being punished by hitting, will tend to grow up to be more aggressive etc. They will learn violent ways of addressing the world. Grusec et al (1978) found telling children to be generous made no difference, showing generosity did make a difference though. This is evidence that " do as I say not as I do " will not work. the most powerful of these influencing factors is Reward. Bandura called this vicarious (substituted) reinforcement. What he meant is that the child observes someone else being rewarded for a particular behaviour and this affects the child in the same way as it …
Functional NMDA and GABAA receptors in pioneer neurons of the cortical marginal zone

Transient pioneer neurons in the neocortical marginal zone generate an early corticofugal axonal projection at E12–E16 ( Meyer et al. 1998 ). We have analysed the functional activity of glutamate and GABA receptors in such cells by measuring changes in intracellular calcium concentrations ([Ca2+]i). The activation of GABAA receptors with muscimol, as well as bath application of glutamate, lead to increases in [Ca2+]i in pioneer neurons. The stimulatory action of glutamate is mostly produced through the NMDA‐type of ionotropic receptors. Metabotropic glutamate receptor activation has no effect on [Ca2+]i. Consistent with such results, immunocytochemical studies showed a prominent expression of GABAA and NMDA receptors in pioneer neurons. The activation of such receptors may be implicated in the remodelling of pioneer neurons during development.
ACSM's Health-Related Physical Fitness Assessment Manual

Chapter One: IntroductionChapter Two: Preactivity ScreeningChapter Three: Resting and Exercise Blood Pressure and Heart RateChapter Four: Anthropometry Body CompositionChapter Five: Musculo-Skeletal Fitness: Flexibility, SED Muscular Strength and Muscular EnduranceChapter Six: Aerobic Capacity MeasurementChapter Seven: Submaximal Cycle and Treadmill Ergometry for Aerobic Capacity PredictionChapter Eight: Maximal Exercise Tests for Aerobic CapacityChapter Nine: Estimates of Energy Expenditures: Metabolic CalculationsChapter Ten: Individualized Exercise ProgrammingAppendice
SOCIAL PERCEPTION AND GROUP EFFECTIVENESS

Abstract : An investigation is being made of the extent to which personal characteristics of team members differentiate effective from less effective teams. An Assumed Similarity (AS) score was obtained by asking a person to describe himself and to predict the self-description given by another person. It is suggested that the person who assumes similarity is a warmer, less critical person. Studies on basketball and surveyor teams indicated that effective teams prefer co-workers with low AS. Preliminary evidence showed that the design of forced-choice instruments where each item has about equal scale value may be inferior to a design in which items grouped together differ in scale value. A method was derived for obtaining a hierarchy index from sociometric ratings.
Vertical 40 nm Impact Ionization MOSFET (I-MOS) for high temperature applications

For the first time we present high temperature electrical characteristics of the vertical Impact Ionization MOSFET. The design of this device suppresses efficiently leakage currents at high temperatures and therefore guarantees MOSFET functionality up to several hundred degC. At 250degC a very good IonToff ratio of 105 as well as leakage currents in the nA range are demonstrated. This makes this device suitable for high temperature applications like automotive.
Social mobility in Europe

1. The Comparative Study of Social Mobility 2. Statistical Methods of Mobility Research 3. Social Mobility in Europe Between 1970 and 2000 4. Social Mobility in West Germany: The Long Arms of History Discovered? 5. Change in Intergenerational Class Mobility in France from the 1970s to the 1990s and its Explanation: An Analysis Following the Casmin Approach 6. The Italian Mobility Regime: 1985-1997 7. Class Transformation and Trends in Social Fluidity in the Republic of Ireland 1973-1994 8. Trends in Intergenerational Class Mobility in Britain in the Late Twentieth Century 9. Equality at a Halt? Social Mobility in Sweden 1976-1999 10. Social Mobility in Norway 1973-1995 11. Intergenerational Mobility in Poland 1972-1988-1994 12. Changes in Intergenerational Class Mobility in Hungary 1973-2000 13. Opportunities, Little Change: Class Mobility in Israeli Society 1974-1991 14. Recent Trends in Intergenerational Occupational Class Reproduction in The Netherlands 1970-1999 15. Conclusions References
Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

Diclofenac is a nonsteroidal anti‐inflammatory drug that causes rare but serious hepatotoxicity, the mechanism of which is unclear. The purpose of the present study was to explore the potential role played by the immune processes. Antibodies to diclofenac metabolite‐modified liver protein adducts were detected in the sera of seven out of seven patients with diclofenac‐induced hepatotoxicity, 12 of 20 subjects on diclofenac without hepatotoxicity, and none of four healthy controls. The antibodies recognized adducts expressed in livers from rats treated with multiple doses of diclofenac, but not in those given single doses. In addition, several potential diclofenac adducts were identified in the liver of a patient with diclofenac‐induced hepatic failure, but not from a normal human donor liver, by immunoblotting with an adduct‐selective rabbit antiserum. To determine whether or not polymorphisms in genes encoding cytokine‐related proteins influence susceptibility to hepatotoxicity, genotyping for the polymorphisms ‐627 in the interleukin (IL)‐10 gene, ‐590 in the IL‐4 gene, and codon 551 in the IL‐4 receptor (IL‐4R) were performed on DNA from 24 patients on diclofenac with hepatotoxicity, 48 subjects on diclofenac without hepatotoxicity, and healthy controls. The frequencies of the variant alleles for IL‐10 and IL‐4 were higher in patients (OR [odds ratio]: 2.8 for IL‐10; 2.6 for IL‐4; 5.3 for IL‐10 + IL‐4) compared with healthy controls and subjects on diclofenac without hepatotoxicity (OR: 2.8 for IL‐10; 1.2 for IL‐4; 5.0 for IL‐10 + IL‐4). In conclusion, the observed polymorphisms, resulting in low IL‐10 and high IL‐4 gene transcription, could favor a T helper (Th)‐2 mediated antibody response to neoantigenic stimulation associated with disease susceptibility. HEPATOLOGY 2004;39:1430–1440. )
Exercise Tolerance Can Be Enhanced through a Change in Work Rate within the Severe Intensity Domain: Work above Critical Power Is Not Constant

Introduction The characterization of the hyperbolic power-time (P-t lim) relationship using a two-parameter model implies that exercise tolerance above the asymptote (Critical Power; CP), i.e. within the severe intensity domain, is determined by the curvature (W’) of the relationship. Purposes The purposes of this study were (1) to test whether the amount of work above CP (W>CP) remains constant for varied work rate experiments of high volatility change and (2) to ascertain whether W’ determines exercise tolerance within the severe intensity domain. Methods Following estimation of CP (208 ± 19 W) and W’ (21.4 ± 4.2 kJ), 14 male participants (age: 26 ± 3; peak V˙O2: 3708 ± 389 ml.min-1) performed two experimental trials where the work rate was initially set to exhaust 70% of W’ in 3 (‘THREE’) or 10 minutes (‘TEN’) before being subsequently dropped to CP plus 10 W. Results W>CP for TEN (104 ± 22% W’) and W’ were not significantly different (P>0.05) but lower than W>CP for THREE (119 ± 17% W’, P<0.05). For both THREE (r = 0.71, P<0.01) and TEN (r = 0.64, P<0.01), a significant bivariate correlation was found between W’ and t lim. Conclusion W>CP and t lim can be greater than predicted by the P-t lim relationship when a decrement in the work rate of high-volatility is applied. Exercise tolerance can be enhanced through a change in work rate within the severe intensity domain. W>CP is not constant.
A comparison of social information processing in children with and without reactive attachment disorder and the association with behavioural difficulties

The aims of this cross-sectional case-control study were to explore the social information processing (SIP) patterns of children with reactive attachment disorder (RAD) and their association with behavioural difficulties. The sample consisted of 23 children with RAD aged 4-12 matched by age and gender with a comparison sample of typically developing peers. Children completed an assessment package investigating the encoding, interpretation, response access and response evaluation components of SIP and their intellectual functioning and verbal comprehension, while caregivers completed two instruments measuring child behavioural difficulties. The children with RAD displayed significantly more errors in encoding, interpretation and response evaluation than the comparison group. There was also a tendency for children with RAD to access more aggressive responses than comparison children. In addition, there were strong associations between aspects of SIP and child behavioural difficulties, with the strongest association between encoding and emotional problems. However, both intellectual functioning and verbal comprehension were significantly associated with behavioural difficulties suggesting these variables may impact on the relationship between SIP and behavioural difficulties. The overall findings suggest that children with RAD process social information in a biased manner and this is partially associated with behavioural outcomes. The strengths and limitations of the study are discussed in addition to suggestions for future research.
Does Monogamy Harm Women? Deconstructing Monogamy with a Feminist Lens

In this paper, we utilize a critical feminist lens to analyze the advantages and disadvantages found within two different romantic relationship configurations: monogamy and polyamory. While visibility of polyamorous relationships has increased in recent years, there is still a lack of information and a plethora of misinformation concerning non-monogamous romantic relationship dynamics (Conley, Moors, Matsick, & Ziegler, 2012; Conley, Ziegler, Moors, Matsick, & Valentine, 2012). One such notion is that polyamory is differentially damaging to women vis-a-vis men. From a phenomenological perspective, sociocultural values dictate that women, unlike men, are prescribed to be dependent upon monogamy in order to define their selfhood; and indeed, research has provided evidence in support of this idea, as women are more apt to be offended by the idea of concurrent multiple relationships and are less likely to report a willingness to engage in these types of relationships than men are (Moors, Conley, Edelstein, & Chopik, under review-a). Using a previous review of monogamy as a starting point (Conley, Ziegler, Moors, Matsick, & Valentine, 2012), we will reanalyze two major points from the review piece: sex benefits and jealousy in monogamous and polyamorous relationships. Throughout, we examine if the presumed benefits of monogamy extend to women or if alternative relationship structures, specifically polyamory, afford greater advantages. Additionally, we consider other benefits that may be unique to polyamory for women, including increased agency, financial resources, and extended social support.
Marching-on-in-degree time-domain integral equation solver with high-level basis functions for transient electromagnetic scattering

In this paper, the transient electromagnetic scattering of the benchmark target, i.e. the NASA almond, is calculated utilizing the marching-on-in-degree time-domain integral equation method with high-level spatial and temporal basis functions. Much memory requirement reduction and unconditionally stable solution in late time can be ensured. The time-domain solution is then Fourier transformed, and wide frequency band information is obtained. As a further discussion of the previous work of the authors, numerical results of the NASA almond are provided and discussed.