Miracle-dz/UniFAR-FTUs huggingface dataset:
Early Hash Join: A Configurable Algorithm for the Efficient and Early Production of Join Results

Minimizing both the response time to produce the first few thousand results and the overall execution time is important for interactive querying. Current join algorithms either minimize the execution time at the expense of response time or minimize response time by producing results early without optimizing the total time. We present a hash-based join algorithm, called early hash join, which can be dynamically configured at any point during join processing to tradeoff faster production of results for overall execution time. We demonstrate that varying how inputs are read has a major effect on these two factors and provide formulas that allow an optimizer to calculate the expected rate of join output and the number of I/O operations performed using different input reading strategies. Experimental results show that early hash join performs significantly fewer I/O operations and executes faster than other early join algorithms, especially for one-to-many joins. Its overall execution time is comparable to standard hybrid hash join, but its response time is an order of magnitude faster. Thus, early hash join can replace hybrid hash join in any situation where a fast initial response time is beneficial without the penalty in overall execution time exhibited by other early join algorithms.
An Efficient Network-on-Chip Architecture Based on the Fat-Tree (FT) Topology

A novel approach for an efficient network-on-chip using a modified Fat Tree is presented. Contention is eliminated and latency is reduced through an improved topology and router architecture. The adopted topology increases performance without a substantial increase in the routing cost. This is achieved by using an improved buffer-less, paremeterizable router architecture. The proposed router architecture is simple to implement yet can achieve the required packet collision avoidance. Simulation results that show the level of performance achieved by both the topology and the router architecture are presented. A throughput of more than 90% is achieved way above the 40-50% usually seen in other networks on chips.
Low-SNR Capacity of Noncoherent Fading Channels

Discrete-time Rayleigh-fading single-input single-output (SISO) and multiple-input multiple-output (MIMO) channels are considered, with no channel state information at the transmitter or the receiver. The fading is assumed to be stationary and correlated in time, but independent from antenna to antenna. Peak-power and average-power constraints are imposed on the transmit antennas. For MIMO channels, these constraints are either imposed on the sum over antennas, or on each individual antenna. For SISO channels and MIMO channels with sum power constraints, the asymptotic capacity as the peak signal-to-noise ratio (SNR) goes to zero is identified; for MIMO channels with individual power constraints, this asymptotic capacity is obtained for a class of channels called transmit separable channels. The results for MIMO channels with individual power constraints are carried over to SISO channels with delay spread (i.e., frequency-selective fading).
Reversible Crystal Plasticity

Partial Contents: 1. Transformation of Dislocations. Dislocation Description of a Phase Transformation Front. 2. Dislocation Theory of Elastic Twinning. Twinning of Crystals: Principal Definitions. 3. Statics and Dynamics of Elastic Twinning. Discovery of Elastic Twinning. Verification of the Validity of the Static Theory in a Description of the Macroscopic Behavior of an Elastic Twin. 4. Thermoelastic Martensitic Transformation. Martensitic Transformation: a Diffusionless Process of Rebuilding the Crystal Lattice. 5. Superelasticity and the Shape Memory Effect. Main Characteristics of Superelasticity and Shape Memory Effects. 6. Reversible Plasticity of Ferroelastics. Ferroelastics: Main Definitions. 7. Investigation of Reversible Plasticity of Crystals by the Acoustic Emission Method. Emission of Sound by Moving Dislocations andTheir Pileups. Methods Used in Experimental Investigations of the Acoustic Emission Generated by a SingleTwin. Acoustic Emission Associated with Elastic Twinning. 8. Influence of Reversible Plasticity of Superconductors on Their Physical Properties. Reversible Changes in the Parameters of Traditional Superconductors under the Action of Elastic Stresses.
The Phytotoxin Albicidin is a Novel Inhibitor of DNA Gyrase

ABSTRACT Xanthomonas albilineans produces a family of polyketide-peptide compounds called albicidins which are highly potent antibiotics and phytotoxins as a result of their inhibition of prokaryotic DNA replication. Here we show that albicidin is a potent inhibitor of the supercoiling activity of bacterial and plant DNA gyrases, with 50% inhibitory concentrations (40 to 50 nM) less than those of most coumarins and quinolones. Albicidin blocks the religation of the cleaved DNA intermediate during the gyrase catalytic sequence and also inhibits the relaxation of supercoiled DNA by gyrase and topoisomerase IV. Unlike the coumarins, albicidin does not inhibit the ATPase activity of gyrase. In contrast to the quinolones, the albicidin concentration required to stabilize the gyrase cleavage complex increases 100-fold in the absence of ATP. The slow peptide poisons microcin B17 and CcdB also access ATP-dependent conformations of gyrase to block religation, but in contrast to albicidin, they do not inhibit supercoiling under routine assay conditions. Some mutations in gyrA, known to confer high-level resistance to quinolones or CcdB, confer low-level resistance or hypersensitivity to albicidin in Escherichia coli. Within the albicidin biosynthesis region in X. albilineans is a gene encoding a pentapeptide repeat protein designated AlbG that binds to E. coli DNA gyrase and that confers a sixfold increase in the level of resistance to albicidin in vitro and in vivo. These results demonstrate that DNA gyrase is the molecular target of albicidin and that X. albilineans encodes a gyrase-interacting protein for self-protection. The novel features of the gyrase-albicidin interaction indicate the potential for the development of new antibacterial drugs.
Variability of Tensile Properties of Fibers from Pseudostem of Banana Plant

This paper reports the variability of mechanical properties of banana fibers with respect to diameter, testing speed and gauge length. We report interesting findings on banana fibers. Tenacity of the fibers significantly improved for the fibers with lower linear density. An increase in speed resulted in improvement of fiber properties to a certain degree. Higher gauge lengths resulted in poor properties due to an increase in flaws in the structure. The banana fibers showed very high variability in linear density and mechanical properties.
Novel Model of Pulmonary Artery Banding Leading to Right Heart Failure in Rats

Background. Congenital heart diseases often involve chronic pressure overload of the right ventricle (RV) which is a major cause of RV dysfunction. Pulmonary artery (PA) banding has been used to produce animal models of RV dysfunction. We have devised a new and easier method of constricting the PA and compared it directly with the partial ligation method. Methods. Eight-week-old male Sprague-Dawley rats (240–260 g) were divided into three groups: sham operation, partial pulmonary artery ligation (PAL) procedure, and pulmonary artery half-closed clip (PAC) procedure. RV function and remodeling were determined by echocardiography and histomorphometry. Results. Surgical mortality was significantly lower in the PAC group while echocardiography revealed significantly more signs of RV dysfunction. At the 8th week after surgery RV fibrosis rate was significantly higher in the PAC group. Conclusions. This procedure of pulmonary artery banding in rats is easier and more efficient than partial ligation.
Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAM) 1, 5 and 6 as Biomarkers in Pancreatic Cancer

Background Aim of this study was to assess the biological function in tumor progression and metastatic process carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1, 5 and 6 in pancreatic adenocarcinoma (PDAC). Experimental Design CEACAM knock down cells were established and assessed in vitro and in a subcutaneous and intraperitoneal mouse xenograft model. Tissue and serum expression of patients with PDAC were assessed by immunohistochemistry (IHC) and by enzyme linked immunosorbent assays. Results Presence of lymph node metastasis was correlated with CEACAM 5 and 6 expression (determined by IHC) and tumor recurrence exclusively with CEACAM 6. Patients with CEACAM 5 and 6 expression showed a significantly shortened OS in Kaplan-Meier survival analyses. Elevated CEACAM6 serum values showed a correlation with distant metastasis and. Survival analysis revealed a prolonged OS for patients with low serum CEACAM 1 values. In vitro proliferation and migration capacity was increased in CEACAM knock down PDAC cells, however, mice inoculated with CEACAM knock down cells showed a prolonged overall-survival (OS). The number of spontaneous pulmonary metastasis was increased in the CEACAM knock down group. Conclusion The effects mediated by CEACAM expression in PDAC are complex, though overexpression is correlated with loco-regional aggressive tumor growth. However, loss of CEACAM can be considered as a part of epithelial-mesenchymal transition and is therefore of rather importance in the process of distant metastasis.
An experimental study of fluid structure interaction of carbon composites under low velocity impact

Abstract : The effect of fluid force on the natural frequencies and damping ratios of vibrating structures in contact with fluid is known as the Fluid Structure Interaction (FSI) problem. It can be interpreted as an added mass to the vibrating structure in the analysis of the dynamic response. Because the density of water is much greater than air, the added mass effect becomes even more critical in understanding the dynamic response of composites in water surroundings. In this study, experimental testing was carried out to investigate FSI of composite laminates immersed in fluid and subjected to low-velocity impact. Square composite laminates of carbon fiber weave and vinyl ester resin of size 305 mm and 2.38 mm nominal thickness were subjected to low velocity impact loading, using a specially developed vertical drop-weight testing machine. The composite samples were fitted with gages to provide real-time information on strain levels generated during impact. Impact tests were performed on four side clamped laminates in air-backed, water-backed, and dry surroundings, and at various impact energies for investigation. The findings of this study will provide a better understanding for the use of composite materials in underwater structural applications where impact loading is expected.
In-plane energy absorption evaluation of 3D printed polymeric honeycombs

ABSTRACT Honeycomb structures have been widely used for impact protection and energy absorption applications. However, studies on such structures have been mainly limited to metallic honeycombs with little research done on polymeric honeycomb structures. The purpose of this paper is to study the in-plane static compressive crushing behaviour and energy absorption capacity of 3D printed polymeric honeycomb structures of different unit cell thicknesses. Uniaxial quasi-static compression tests were performed on hexagonal honeycomb structures of varying wall thicknesses printed in Nylon 12 by fused deposition modelling 3D printing. Numerical simulations using ABAQUS/Explicit finite element analysis software were performed to determine the compressive behaviour of the same honeycomb structures. Gibson and Ashby’s analytical model was also used to determine the theoretical plateau stresses of the honeycombs. The experimental compressive behaviour, plateau stress and energy absorption capacity of the honeycombs were compared with numerical and analytical values. It was found that experimental results obtained are in good agreement with computational numerical solutions and with the theoretical model for all cell wall thickness to cell wall length ratios. It was also observed that the plastic deformation of hexagonal honeycombs are different in its two main in-plane directions and 3D printing can be applied to generate honeycomb structures of varying geometry and energy absorption capacity with predictable performance.
Christian conservatism and prominent sociopolitical values among teacher-education students in a southeastern university

Teacher-education students attending a state university in the Southeastern United States responded to measures of Christian conservatism (theological fundamentalism and political evangelicalism) and sociopolitical values (e.g., nationalism, internationalism, patriotism, respect for civil liberties, and tolerance of dissent). Most of the measures demonstrated adequate internal consistency. Although both Christian conservatism measures correlated significantly with all sociopolitical measures except internationalism, political evangelicalism was more strongly related to the comparison sociopolitical perspectives than was theological fundamentalism. The Christian conservatism measures correlated most strongly with (a) respect for civil liberties and (b) tolerance of dissent. In both cases, the relationships were negative.
Human CD56dimCD16dim Cells As an Individualized Natural Killer Cell Subset

Human natural killer (NK) cells can be subdivided in several subpopulations on the basis of the relative expression of the adhesion molecule CD56 and the activating receptor CD16. Whereas blood CD56brightCD16dim/− NK cells are classically viewed as immature precursors and cytokine producers, the larger CD56dimCD16bright subset is considered as the most cytotoxic one. In peripheral blood of healthy donors, we noticed the existence of a population of CD56dimCD16dim NK cells that was frequently higher in number than the CD56bright subsets and even expanded in occasional control donors but also in transporter associated with antigen processing-deficient patients, two familial hemophagocytic lymphohistiocytosis type II patients, and several common variable immunodeficiency patients. This population was detected but globally reduced in a longitudinal cohort of 18 HIV-1-infected individuals. Phenotypically, the new subset contained a high percentage of relatively immature cells, as reflected by a significantly stronger representation of NKG2A+ and CD57− cells compared to their CD56dimCD16bright counterparts. The phenotype of the CD56dimCD16dim population was differentially affected by HIV-1 infection as compared to the other NK cell subsets and only partly restored to normal by antiretroviral therapy. From the functional point of view, sorted CD56dimCD16dim cells degranulated more than CD56dimCD16bright cells but less than CD56dimCD16− NK cells. The population was also identified in various organs of immunodeficient mice with a human immune system (“humanized” mice) reconstituted from human cord blood stem cells. In conclusion, the CD56dimCD16dim NK cell subpopulation displays distinct phenotypic and functional features. It remains to be clarified if these cells are the immediate precursors of the CD56dimCD16bright subset or placed somewhere else in the NK cell differentiation and maturation pathway.
Influence of plasticity on corrosion and stress corrosion cracking behaviour in near neutral pH environment

This study focused on the effect of plasticity on stress corrosion cracking of pipeline steel (X-52) in near neutral pH environment. A simulated near neutral pH soil solution, referred to as C-1, was used for all the tests. The effects of plastic deformation on both corrosion current and open circuit potential were studied. Crack advance was measured in samples with various amounts of plastic deformation by slow strain rate tests and corrosion fatigue tests using potential drop to measure crack advance. Crack morphologies and the crack features on the fracture surface were observed by SEM. All the cracking tests indicated that the stress corrosion cracking rate was enhanced by the plastic deformation. The electrochemical tests showed that corrosion current increased with increasing plastic deformation. The relationship between the cracking mechanisms and prior plastic deformation are discussed.
Mathematical model of the morphogenesis checkpoint in budding yeast

The morphogenesis checkpoint in budding yeast delays progression through the cell cycle in response to stimuli that prevent bud formation. Central to the checkpoint mechanism is Swe1 kinase: normally inactive, its activation halts cell cycle progression in G2. We propose a molecular network for Swe1 control, based on published observations of budding yeast and analogous control signals in fission yeast. The proposed Swe1 network is merged with a model of cyclin-dependent kinase regulation, converted into a set of differential equations and studied by numerical simulation. The simulations accurately reproduce the phenotypes of a dozen checkpoint mutants. Among other predictions, the model attributes a new role to Hsl1, a kinase known to play a role in Swe1 degradation: Hsl1 must also be indirectly responsible for potent inhibition of Swe1 activity. The model supports the idea that the morphogenesis checkpoint, like other checkpoints, raises the cell size threshold for progression from one phase of the cell cycle to the next.
The Status of Dosage Compensation in the Multiple X Chromosomes of the Platypus

Dosage compensation has been thought to be a ubiquitous property of sex chromosomes that are represented differently in males and females. The expression of most X-borne genes is equalized between XX females and XY males in therian mammals (marsupials and "placentals") by inactivating one X chromosome in female somatic cells. However, compensation seems not to be strictly required to equalize the expression of most Z-borne genes between ZZ male and ZW female birds. Whether dosage compensation operates in the third mammal lineage, the egg-laying monotremes, is of considerable interest, since the platypus has a complex sex chromosome system in which five X and five Y chromosomes share considerable genetic homology with the chicken ZW sex chromosome pair, but not with therian XY chromosomes. The assignment of genes to four platypus X chromosomes allowed us to examine X dosage compensation in this unique species. Quantitative PCR showed a range of compensation, but SNP analysis of several X-borne genes showed that both alleles are transcribed in a heterozygous female. Transcription of 14 BACs representing 19 X-borne genes was examined by RNA-FISH in female and male fibroblasts. An autosomal control gene was expressed from both alleles in nearly all nuclei, and four pseudoautosomal BACs were usually expressed from both alleles in male as well as female nuclei, showing that their Y loci are active. However, nine X-specific BACs were usually transcribed from only one allele. This suggests that while some genes on the platypus X are not dosage compensated, other genes do show some form of compensation via stochastic transcriptional inhibition, perhaps representing an ancestral system that evolved to be more tightly controlled in placental mammals such as human and mouse.
Supernovae, CMB, and gravitational leakage into extra dimensions

We discuss observational constraints coming from CMB and type Ia supernovae for the model of an accelerated universe produced by gravitational leakage into extra dimensions. Our fits indicate that the model is currently in agreement with the data. We also give the equations governing the evolution of cosmological perturbations. Future observations will be able to severely constrain the model.
Effect of endurance training on blood pressure regulation, biomarkers and the heart in subjects at a higher age

We reported previously that two otherwise identical training programs at lower (LI) and higher intensity (HI) similarly reduced resting systolic blood pressure (BP) by approximately 4–6 mmHg. Here, we determined the effects of both programs on BP‐regulating mechanisms, on biomarkers of systemic inflammation and prothrombotic state and on the heart. In this cross‐over study (3 × 10 weeks), healthy participants exercised three times 1 h/week at, respectively, 33% and 66% of the heart rate (HR) reserve, in a random order, with a sedentary period in between. Measurements, performed at baseline and at the end of each period, involved blood sampling, HR variability, systolic BP variability (SBPV) and cardiac magnetic resonance imaging. Thirty‐nine participants (18 men; mean age 59 years) completed the study. Responses were not different between both programs (P>0.05). Pooled data from LI and HI showed a reduction in HR (−4.3 ± 8.1%) and an increase in stroke volume (+11 ± 23.1%). No significant effect was seen on SBPV, plasma renin activity, basal nitric oxide and left ventricular mass. Our results suggest that the BP reduction observed appears to be due to a decrease in systemic vascular resistance; training intensity does not significantly affect the results on mechanisms, biomarkers and the heart.
The ARBAC97 model for role-based administration of roles: preliminary description and outline

In role-based access control (RBAC) permissions are associated with roles, and users are made members of roles thereby acquiring the roles’ permissions. The motivation behind RBAC is to simplify administration. An appealing possibility is to use RBAC itself to manage RBAC, to further provide administrative convenience, especially in decentralizing administrative authority, responsibility and chores. This paper describes the motivation, intuition and outline of a new model for RBAC administration called ARBAC97 (administrative RBAC ‘97). ARBAC97 has three components: URA97 (user-role assignment ‘97), PRA97 (permissionrole assignment ‘97) and RRA97 (role-role assignment ‘97). URA97 was recently defined by Sandhu and Bhamidipati [SB97]. ARBAC97 incorporates URA97, builds upon it to define PRA97 and some components of RRA97, and introduces additional concepts in developing RRA97. *This work is partially supported by the National Science Fmmdation at the Laboratory for Information Security Technology at George Mason University and the National Institute of Standards and Technology at SETA Corporation. All correspondence should be addressed to Ravi Sandhu, ISSE Department, Mail Stop 4A4, George Mason University, Fairfax, VA 22030, sandhu@isse.gmu.edu, wvw.list. gmu.edu.