Miracle-dz/UniFAR-FTUs huggingface dataset:
Social Structural and Social Psychological Bases of Environmental Concern

Efforts to explain environmental concern as a function of social structure have revealed some weak but reliable associations. Stronger associations have been found between environmental concern and social psychological variables including attitudes, beliefs, and worldviews. The authors used the 1993 General Social Survey to explore a conceptual framework that postulates four causal levels: social structural factors and early socialization experiences; general worldview and ideology about humanity and the environment; specific attitudes, beliefs, and cognitions about environmental issues; and environmentally relevant behavior. Each class of variable has explanatory power beyond that given by other classes of variables, with the social psychological variables generally adding more explanatory power than the structural variables. The patterns are different, however, for the five behavioral indicators. Efforts to explain the structural influences as indirect, operating through the social psychological variables, were mainly unsuccessful.
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Genes overlap across psychiatric disease Many genome-wide studies have examined genes associated with a range of neuropsychiatric disorders. However, the degree to which the genetic underpinnings of these diseases differ or overlap is unknown. Gandal et al. performed meta-analyses of transcriptomic studies covering five major psychiatric disorders and compared cases and controls to identify coexpressed gene modules. From this, they found that some psychiatric disorders share global gene expression patterns. This overlap in polygenic traits in neuropsychiatric disorders may allow for better diagnosis and treatment. Science, this issue p. 693 Neuropsychiatric disease patients have both shared and distinct gene expression pattern changes in the brain compared with controls. The predisposition to neuropsychiatric disease involves a complex, polygenic, and pleiotropic genetic architecture. However, little is known about how genetic variants impart brain dysfunction or pathology. We used transcriptomic profiling as a quantitative readout of molecular brain-based phenotypes across five major psychiatric disorders—autism, schizophrenia, bipolar disorder, depression, and alcoholism—compared with matched controls. We identified patterns of shared and distinct gene-expression perturbations across these conditions. The degree of sharing of transcriptional dysregulation is related to polygenic (single-nucleotide polymorphism–based) overlap across disorders, suggesting a substantial causal genetic component. This comprehensive systems-level view of the neurobiological architecture of major neuropsychiatric illness demonstrates pathways of molecular convergence and specificity.
Hearing loss and antiretroviral therapy in patients infected with HIV-1.

OBJECTIVE To explore the association between hearing loss and antiretroviral therapy in human immunodeficiency virus type 1 (HIV-1)-infected persons. DESIGN Case-control study. SETTING University-based HIV clinic. PARTICIPANTS Volunteer sample of 99 HIV-infected patients. INTERVENTIONS Standardized interview focusing on risks for hearing loss, review of clinic pharmacy records, and hearing tests by portable audiometry. MAIN OUTCOME MEASURE Hearing loss, defined as threshold of more than a 25-dB hearing level at 4000 Hz in 1 or both ears. RESULTS Hearing loss was common, seen in 29 subjects (29%). It was significantly associated with age and history of ear infection and tended to be more common in subjects prescribed antiretroviral agents. An interaction existed between age and antiretroviral therapy; the association between hearing loss and antiretroviral therapy was significant for subjects aged 35 years or older, but not for subjects younger than 35 years. In subjects aged 35 years or older, this association remained significant using a multivariate model that included those variables found to have the greatest potential for confounding (odds ratio, 4.6; 95% confidence interval, 1.0-20.5; P = .05). CONCLUSIONS Hearing loss is common among HIV-infected individuals and is associated with antiretroviral therapy in those aged 35 years or older.
Development and Degeneration of Cone Bipolar Cells Are Independent of Cone Photoreceptors in a Mouse Model of Retinitis Pigmentosa

Retinal photoreceptors die during retinal synaptogenesis in a portion of retinal degeneration. Whether cone bipolar cells establish regular retinal mosaics and mature morphologies, and resist degeneration are not completely understood. To explore these issues, we backcrossed a transgenic mouse expressing enhanced green fluorescent protein (EGFP) in one subset of cone bipolar cells (type 7) into rd1 mice, a classic mouse model of retinal degeneration, to examine the development and survival of cone bipolar cells in a background of retinal degeneration. Our data revealed that both the development and degeneration of cone bipolar cells are independent of the normal activity of cone photoreceptors. We found that type 7 cone bipolar cells achieved a uniform tiling of the retinal surface and developed normal dendritic and axonal arbors without the influence of cone photoreceptor innervation. On the other hand, degeneration of type 7 cone bipolar cells, contrary to our belief of central-to-peripheral progression, was spatially uniform across the retina independent of the spatiotemporal pattern of cone degeneration. The results have important implications for the design of more effective therapies to restore vision in retinal degeneration.
It Ain't Easy Being Green

Abstract The “green gap” is traditionally thought of as the gap between how consumers intend to behave regarding green living and how they actually behave. We extend the idea of the green gap by demonstrating a different kind of disconcerting green gap. There are three levels of green advertising—with tensions embedded in their differing agendas. An ethnographic content analysis and phenomenological interviews reveal that there is a macro agenda of saving the planet associated with nonprofit green advertisers. There is a meso agenda associated with for- profit enterprises. These commercial approaches do not appear to be aligned with consumers' micro agendas of saving one's own part of the planet (or at the very least, of not wasting one's part of it, as perpetuated by consumers). We then provide solutions for green advertisers in bridging this unsettling green gap among for-profit advertisers, nonprofit advertisers, and consumers who want to make being green and less wasteful easier in their everyday lives.
Humoral Regulation of Blood Flow to Choroid Plexus: Role of Arginine Vasopressin

The goal of this study was to examine humoral mechanisms that regulate blood flow to the choroid plexus. We determined the effects of arginine vasopressin on blood flow (mkrospheres) to the choroid plexus in anesthetized and awake rabbits. In anesthetized rabbits, blood flow to the choroid plexus was 342 ± 31 (mean ± SEM) ml/min/100 g under control conditions. Intravenous infusion of vasopressin at 4 and 40 mU/kg increased plasma vasopressin levels from 11 ± 1 to 55 ± 15 and 441 ± 120 pg/ml, respectively, and blood flow to the choroid plexus decreased by 48 ± 6% and 70 ± 4%. Cerebral blood flow was not affected by infusion of vasopressin. Similar responses to infusion of vasopressin were observed in awake rabbits. The V1 antagonist [d(CH2)5Tyr(Me)AVP] (10 μg/kg i.v.) had no effect on resting blood flow, but abolished the effect of vasopressin on blood flow to the choroid plexus. Vasoconstrictor responses of the choroid plexus to intravenous infusion of phenylephrine were not attenuated by the V1 antagonist. Thus, circulating vasopressin, at plasma levels that are observed under physiological and pathophysiological conditions, has marked effects on blood flow to the choroid plexus. These effects appear to be mediated through a V1 receptor. We speculate that vasopressin may play an important role in regulation of blood flow to the choroid plexus and perhaps in the regulation of cerebrospinal fluid production.
Medical thoracoscopy

Purpose of review The technique and clinical applications of medical thoracoscopy have substantially evolved in the last few decades. The recent development of a semirigid thoracoscope, which is handled similarly to a bronchoscope, has made this procedure more attractive to pulmonologists. We will review the latest data on clinical applications, recently developed techniques, and safety of medical thoracoscopy, focusing mainly on its role in thoracic malignancies. Recent findings Recent data confirm the high diagnostic yield of medical thoracoscopy – both with rigid and semirigid instruments – in detecting pleural metastases and determining the origin of pleural effusions. The degree of pleural adhesions found during thoracoscopy has been proposed by some authors as a prognostic factor for survival in patients with malignant pleural effusion. A large prospective multicenter study has established the safety of talc poudrage with large-particle talc, showing no cases of acute respiratory distress syndrome. Summary Medical thoracoscopy is an excellent tool to establish diagnosis in patients with exudative pleural effusion of unclear origin. It is highly valuable in clarifying the origin of pleural effusions in patients with lung cancer, as the presence of a malignant pleural effusion is associated with poor survival and precludes the possibility of treatment with curative intention. Pleurodesis with talc poudrage is efficacious and well tolerated, especially with the use of large-particle talc.
A multi-deme parallelization of a memetic algorithm for the weight setting problem in OSPF and DEFT

The Internet is divided into Autonomous Systems, which cont rol their intra-domain traffic by using interior gateway protocols. The most common protocol used today is Open Shortest Path First (OSPF). OSPF routes traffic on shortest paths defined by integer link weights. The weight setting problem is to find weights that optimize the resultin g raffic, for example to minimize network congestion. A recently proposed protocol called Distribut ed Exponentially-weighted Flow Splitting (DEFT) sends flow on non-shortest paths, with an exponential penalty for longer paths. Since these problems are hard to solve exactly, several heuristics have been proposed. We propose a parallel, multi-deme version of a memetic algorithm to solve the weigh t setting problem in DEFT. It consists of a shared memory parallelization of the (single deme) meme tic algorithm, as well as instances of the memetic algorithm running in parallel, and migrating so luti ns among populations according to the island model. Computational results show a reduction of execution time, and an improvement of solution quality compared to the original memetic algorith m.
Special educational needs, disability and school accountability: an international perspective

Standards-based accountability approaches in education are increasingly being adopted in many industrialised countries. This tends to involve the scrutiny of student performance in national academic tests and then holding schools accountable for subsequent progress. International assessments such as Programme for International Student Assessment (PISA) are not accountability measures in themselves, but are often utilised in a similar way and national policies are judged against performance in these tests. Drawing upon the examples of PISA and national assessments in the USA, this paper explores how students with special educational needs and disability (SEND) are included in, and served by, these assessment policies. The analysis suggests that while these approaches are inclusive in their intent (most obviously through efforts to include students with SEND in testing) they may poorly represent the progress of these students. It is argued that more equitable inclusion of students with SEND must find a balance between accountability measures which measure performance in traditional attainment-focused tests and other relevant assessments which are meaningful to the given student and/or SEND sub-group.
Well, I Wouldn't be Any Worse Off, Would I, Than I am Now? A Qualitative Study of Decision-Making, Hopes, and Realities of Adults With Type 1 Diabetes Undergoing Islet Cell Transplantation

Background For selected individuals with type 1 diabetes, pancreatic islet transplantation (IT) prevents recurrent severe hypoglycemia and optimizes glycemia, although ongoing systemic immunosuppression is needed. Our aim was to explore candidates and recipients' expectations of transplantation, their experience of being on the waiting list, and (for recipients) the procedure and life posttransplant. Methods Cross-sectional qualitative research design using semistructured interviews with 16 adults (8 pretransplant, 8 posttransplant; from 4 UK centers (n = 13) and 1 Canadian center (n = 3)). Interviews were audio-recorded, transcribed, and underwent inductive thematic analysis. Results Interviewees were aged (mean ± SD) 52 ± 10 years (range, 30-64); duration of diabetes, 36 ± 9 years (range, 21-56); 12 (75%) were women. Narrative accounts centered on expectations, hopes, and realities; decision-making; waiting and uncertainty; the procedure, hospital stay, and follow-up. Expected benefits included fewer severe hypoglycemic episodes, reduced need for insulin, preventing onset/progression of complications and improved psychological well-being. These were realized for most, at least in the short term. Most interviewees described well-informed, shared decision-making with clinicians and family, and managing their expectations. Although life “on the list” could be stressful, and immunosuppressant side effects were severe, interviewees reported “no regrets. ” Posttransplant, interviewees experienced increased confidence, through freedom from hypoglycemia and regained glycemic control, which tempered any disappointment about continued reliance on insulin. Most viewed their transplant as a success, though several reflected upon setbacks and hidden hopes for becoming “insulin-free. ” Conclusions Independently undertaken interviews demonstrated realistic and balanced expectations of IT and indicate how to optimize the process and support for future IT candidates.
Differing perceptions in the feedback process

Feedback is central to the development of effective learning, yet is comparatively underresearched. This article seeks to examine the notion of written feedback on assignments and argue that this feedback process is more complex than is sometimes acknowledged. The author illustrates the problematic nature of assignment feedback by drawing on a large‐scale questionnaire survey conducted across eight universities, and then analysing the issue in more depth though fine‐grained data collected from students in a teacher education institute. The article is framed by the concepts of discourse, power and emotion. It highlights a number of different perceptions of students and tutors towards the assessment, marking and feedback process. The author concludes by arguing that ‘assessment dialogues’ are a way forward to mitigate some of the mistrust or misconceptions that may be unwanted outcomes of the assessment process.
Peer Review Comments Provided by High- and Low-Proficiency L2 Learners: A Comparative Study

This study explored the variations in peer review comments provided by L2 writers of high and low proficiencies. Two sampling procedures were used. First, convenience sampling was used to locate a college essay composition course as the setting of the study. Second, purposeful sampling was used to identify high- and low-performing writers as the subjects, from whom the peer review comments were collected and analyzed. An instruction-learning cycle on argumentative essay writing was conducted for 4 weeks. Each student was subsequently provided with the same sample argumentative essay and a peer review form to conduct the review. The rubrics on the review form included introduction, support for position, sequence, refutation, conclusion, voice, and grammar and spelling. Content analysis was conducted to compare the manner in which the comments varied among students of different writing proficiency levels. The results indicate that, although identifying problems was the dominant comment type of both high- and low-performing writers, high-performing writers tended to provide more details when explaining the identified problems and offering suggestions for revisions. The findings are discussed regarding the implications to peer review training.
Symptom Clusters and Quality of Life in Hospice Patients with Cancer

Background: Symptom control is an important part of palliative care and important to achieve optimal quality of life (QOL). Studies have shown that patients with advanced cancer suffer from diverse and often severe physical and psychological symptoms. The aim is to explore the influence of symptom clusters on QOL among patients with advanced cancer. Materials and Methods: 709 patients with advanced cancer were recruited to participate in a clinical trial focusing on symptom management and QOL. Patients were adults newly admitted to hospice home care in one of two hospices in southwest Florida, who could pass mental status screening. The instruments used for data collection were the Demographic Data Form, Memorial Symptom Assessment Scale (MSAS), and the Hospice Quality of Life Index-14. Results: Exploratory factor analysis and multiple regression were used to identify symptom clusters and their influence on QOL. The results revealed that the participants experienced multiple concurrent symptoms. There were four symptom clusters found among these cancer patients. Individual symptom distress scores that were the strongest predictors of QOL were: feeling pain; dry mouth; feeling drowsy; nausea; difficulty swallowing; worrying and feeling nervous. Conclusions: Patients with advanced cancer reported various concurrent symptoms, and these form symptom clusters of four main categories. The four symptoms clusters have a negative influence on patients’ QOL and required specific care from different members of the hospice healthcare team. The results of this study should be used to guide health care providers’ symptom management. Proper attention to symptom clusters should be the basis for accurate planning of effective interventions to manage the symptom clusters experienced by advanced cancer patients. The health care provider needs to plan ahead for these symptoms and manage any concurrent symptoms for successful promotion of their patient’s QOL.
Social Learning Theory and Human Reinforcement

Scholars differ in their assumptions about the strength of accumulated evidence concerning social learning theory. One area of potential weakness is a possible dearth of evidence regarding differential reinforcement, the theory's central causal mechanism. We report results from a systematic review of (1) a sample of experimental studies concerning human reinforcement learning as well as (2) criminological/sociological studies cited by proponents as supportive of social learning theory. This review is designed to assess the empirical basis for reinforcement and social learning. It suggests that results of experimental research, though supportive of the reinforcement process, may be limited in applicability to social learning theory's hypotheses regarding differential reinforcement, and direct tests of differential reinforcement hypotheses are rare in the non-experimental literature. We conclude that the strength of social learning theory could be enhanced by more thorough and direct testing of reinforcement hypotheses and we offer suggestions about how to accomplish that.
VERT: automatic evaluation of video summaries

Video Summarization has become an important tool for multimedia information processing, but the automatic evaluation of a video summarization system remains a challenge. A major issue is that an ideal "best" summary does not exist, although people can easily distinguish "good" from "bad" summaries. A similar situation arise in machine translation and text summarization, where specific automatic procedures, respectively BLEU and ROUGE, evaluate the quality of a candidate by comparing its local similarities with several human-generated references. These procedures are now routinely used in various benchmarks. In this paper, we extend this idea to the video domain and propose the VERT (Video Evaluation by Relevant Threshold) algorithm to automatically evaluate the quality of video summaries. VERT mimics the theories of BLEU and ROUGE, and counts the weighted number of overlapping selected units between the computer-generated video summary and several human-made references. Several variants of VERT are suggested and compared.
An Adaptive Online HDP-HMM for Segmentation and Classification of Sequential Data

In the recent years, the desire and need to understand sequential data has been increasing, with particular interest in sequential contexts such as patient monitoring, understanding daily activities, video surveillance, stock market and the like. Along with the constant flow of data, it is critical to classify and segment the observations on-the-fly, without being limited to a rigid number of classes. In addition, the model needs to be capable of updating its parameters to comply with possible evolutions. This interesting problem, however, is not adequately addressed in the literature since many studies focus on offline classification over a pre-defined class set. In this paper, we propose a principled solution to this gap by introducing an adaptive online system based on Markov switching models with hierarchical Dirichlet process priors. This infinite adaptive online approach is capable of segmenting and classifying the sequential data over unlimited number of classes, while meeting the memory and delay constraints of streaming contexts. The model is further enhanced by introducing a learning rate, responsible for balancing the extent to which the model sustains its previous learning (parameters) or adapts to the new streaming observations. Experimental results on several variants of stationary and evolving synthetic data and two video datasets, TUM Assistive Kitchen and collatedWeizmann, show remarkable performance in segmentation and classification, particularly for evolutionary sequences with changing distributions and/or containing new, unseen classes.
Sex Differences in Violent versus Non-Violent Life-Threatening Altruism

Many studies on Hamilton's (1964) inclusive fitness theory have used the burning house and kidney donation examples of life-threatening altruism. However, these examples may not be sufficiently exhibiting the risk involved with life-threatening altruism that would have occurred in hunter-gatherer societies, such as fighting off attackers and/or predators. The present study examined participants' estimated likelihood to perform altruistic acts for specific kin members/friends in two violent life-threatening situations (i.e., being mugged and being chased) and two non-violent life-threatening situations (i.e., the burning house and kidney donation examples). Participants were 216 undergraduate students who completed a questionnaire on altruism toward an actual kin member/friend. Each questionnaire contained four life-or-death scenarios (two violent and two non-violent) in which either the participant's sibling, cousin, or best friend was in danger and needed help. Results indicated that people were more likely to help siblings than cousins and friends in both the violent and non-violent hypothetical scenarios. Participants indicated a greater likelihood to help people in violent situations than in non-violent situations. Women indicated a greater estimated likelihood than men to help people in non-violent situations while men indicated a greater estimated likelihood than women to help people in violent situations. Both male and female participants indicated a greater estimated likelihood to help women than men in violent situations.