Miracle-dz/UniFAR-FTUs huggingface dataset:
A synthesis of Ethiopian agricultural technical efficiency: A meta-analysis

In Ethiopia, technical efficiency studies started about three decades ago. These studies have reached different conclusions regarding agriculture efﬁciency based on technical efficiency scores. This study represents the first attempt to use meta-analysis to examine the mean technical efficiency estimates in agriculture in Ethiopia. The current study employed 45 frontier studies published from 1993 to 2014 for the meta-analysis. The study employed fractional regression to model for the meta-regression analysis. The result of the study shows that there is no publication bias in technical efficiency studies in Ethiopia. The meta-analysis result shows the overall mean technical efficiencies are 68 and 71% based on fixed effect model and random effect model, respectively, suggesting that there are still opportunities for improvement in the efficiency of Ethiopian agriculture. The result also shows that technical efficiency was found to be decreasing over years for studies carried out in all the four regions together (Tigray, Amhara, Oromia, and South). Overall, the study obtained moderator variables (that is, wheat, maize, sample size, food crop, number of inputs) significantly affecting the estimation of the reported mean technical efficiencies in primary studies across the four meta-regression model specifications. The finding of the decline in technical efficiency over years implies that even though there is a scope of improving efficiency in the country, government should also consider side by side introduction and dissemination of new agricultural technologies to reverse the decreasing technical efficiency. This will ultimately boost the country’s agricultural and food production. Besides, the results call upon researchers and academicians to be curious in identifying study-specific attributes, which are essential for modeling farm-level efficiency. Key words: Meta-analysis, technical efficiency, fixed effect and random effect models.
Improvement of kink and beam steering characteristics of 0.98-μm GaInAs-GaInP high-power lasers utilizing channel ion implantation

We demonstrate a kink and beam steering free operation of 0.98-/spl mu/m GaInAs-GaInP high-power ridge waveguide (RW) lasers utilizing channel ion implantation. The ion-implanted regions along the both sides of the ridge effectively suppressed the excitation of higher order lateral modes, which causes beam steering and kink. The maximum power without beam steering and kink has been achieved over 250 mW for channel ion-implanted RW lasers with 1.8-3.7-/spl mu/m ridge width, compared to 120-mW maximum power without the channel ion implantation.
Does Superior Knowledge Management Increase Shareholder Value

In recent years firms have dramatically increased their expenditures on "knowledge management" (KM), where KM can be defined as the processes managers use to create new knowledge and leverage existing knowledge. Economic theory argues that knowledge is an important driver of firm value and anecdotal evidence suggests that firms with superior KM practices outperform their peers. But while proponents argue that KM increases shareholder value, critics label it a fad, arguing that KM does not benefit shareholders. Further, prior research that attempts to link KM to shareholder value has limitations that make it difficult to unambiguously interpret its findings. The purpose of this study is to provide more definitive evidence on this link by using short window event study methodology to investigate whether KM leads to increased shareholder value, as well as to provide insights into how capital market participants process KM- related information. Specifically, we examine the stock market reaction to companies receiving the "Most Admired Knowledge Enterprise" (MAKE) award, which recognizes companies that excel at KM. We find that MAKE winners experience positive abnormal returns around the award announcement, consistent with KM increasing shareholder value. We also find that MAKE winners report superior operating performance relative to their peers subsequent to the receipt of the award, and that analysts make significant upward revisions to winners' earnings forecasts during the month following the award. Taken together, our findings are consistent with KM enhancing firm value. These findings are consistent with economic theory that argues knowledge is a fundamental driver of firm value, and with KM literature in a variety of business disciplines that alleges superior KM practices provide firms with a competitive advantage.
Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia.

BACKGROUND & AIMS The nuclear factor kappaB (NF-kappaB)/IkappaB-kinase-beta (IKKbeta) pathway has been shown to represent a key link between inflammation and cancer, inducing pro-inflammatory cytokines in myeloid cells and anti-apoptotic pathways in epithelial cells. However, the role of NF-kappaB pathway in gastric carcinogenesis and injury has not been well-defined. We derived mice with a conditional knockout of IKKbeta in gastric epithelial cells (GECs) and myeloid cells, and examined responses to ionizing radiation (IR) and Helicobacter felis infection. METHODS Ikkbeta(Deltastom) mice were generated by crossing Foxa3-Cre mice to Ikkbeta(F/F) mice. Cellular stress was induced with IR and H felis in Ikkbeta(Deltastom), Ikkbeta(F/F), and cis-NF-kappaB-enhanced green fluorescent protein (GFP) reporter mice. Gastric histopathology, apoptosis, proliferation, necrosis, reactive oxygen species, and expression of cytokines, chemokines, and anti-apoptotic genes were assessed. The role of myeloid IKKbeta in these models was studied by crosses with LysM-Cre mice. RESULTS NF-kappaB activity was upregulated in myeloid cells with acute H felis infection, but in GECs by IR or long-term H felis infection during progression to dysplasia. Deletion of IKKbeta in GECs led to increased apoptosis, reactive oxygen species, and cellular necrosis, and resulted in up-regulation of interleukin-1alpha and down-regulation of anti-apoptotic genes. Loss of IKKbeta in GECs resulted in worse inflammation and more rapid progression to gastric preneoplasia, while loss of IKKbeta in myeloid cells inhibited development of gastric atrophy. CONCLUSIONS The loss of IKKbeta/NF-kappaB signaling in GECs results in increased apoptosis and necrosis in response to cellular stress, and accelerated development of dysplasia by Helicobacter infection.
Multimarker Approach to Evaluate the Incidence of the Metabolic Syndrome and Longitudinal Changes in Metabolic Risk Factors: The Framingham Offspring Study

Background— The metabolic syndrome (MetS) is associated with increased cardiovascular risk. We evaluated the relative contributions of circulating biomarkers representing distinct biological pathways to the incidence of MetS and to longitudinal changes of its constituent risk factors. Methods and Results— We measured 8 circulating biomarkers reflecting inflammation (C-reactive protein), hemostasis (plasminogen activator inhibitor-1, fibrinogen), neurohormonal activity (aldosterone, renin, B-type natriuretic peptide, N-terminal proatrial natriuretic peptide), and endothelial dysfunction (homocysteine) in 2292 Framingham Offspring Study participants (mean age, 57 years; 56% women). We related the biomarker panel to incidence of MetS on follow-up initially and then related biomarkers associated with incident MetS to longitudinal change in its components. On follow-up (mean, 2.9 years), 282 participants (of 1473 participants without prevalent MetS at baseline) developed MetS. After adjustment for clinical risk factors, the biomarker panel was associated with incident MetS (P=0.008). On backward elimination, plasminogen activator inhibitor-1 and aldosterone remained associated with incident MetS (multivariable-adjusted odds ratio per 1-SD increment log marker, 1.31 [P=0.004] and 1.21 [P=0.015], respectively). In multivariable analyses evaluating longitudinal change in MetS components (analyzed as continuous variables), plasminogen activator inhibitor-1 was significantly and positively associated with changes in fasting glucose, systolic blood pressure, and triglycerides (all P<0.05). Serum aldosterone was associated positively with change in systolic blood pressure (P=0.023) and inversely with change in high-density lipoprotein cholesterol (P=0.001). Conclusions— Higher circulating plasminogen activator inhibitor-1 and aldosterone levels are associated with the development of MetS and with longitudinal change of its components, suggesting that these biomarkers and related pathways play a key role in mediating metabolic risk.
Language modeling with sum-product networks

Sum product networks (SPNs) are a new class of deep probabilistic models. They can contain multiple hidden layers while keeping their inference and training times tractable. An SPN consists of interleaving layers of sum nodes and product nodes. A sum node can be interpreted as a hidden variable, and a product node can be viewed as a feature capturing rich interactions among an SPN’s inputs. We show that the ability of SPN to use hidden layers to model complex dependencies among words, and its tractable inference and learning times, make it a suitable framework for a language model. Even though SPNs have been applied to a variety of vision problems [1, 2], we are the first to use it for language modeling. Our empirical comparisons with six previous language models indicate that our SPN has superior performance.
CD8 T Cells Activated in Distinct Lymphoid Organs Differentially Express Adhesion Proteins and Coexpress Multiple Chemokine Receptors

Previous work from this laboratory showed that generation of memory CD8 T cells by different immunization routes correlates with control of tumors growing in distinct sites. We hypothesized that effector CD8 T cell expression of adhesion proteins and chemokine receptors would be influenced by activation in different secondary lymphoid organs. In this report, CD8 T cells were activated by immunization with bone marrow-derived dendritic cells via i.p., i.v. , or s.c. routes. Three distinct populations of activated CD8 T cells arise in mesenteric, axillary/brachial, and mediastinal lymph nodes and spleen based on differential expression of α4β7 integrin, E-selectin ligand, and α4β1 integrin, respectively. In contrast, three subsets of CD8 T cells defined by differential expression of P-selectin ligand and chemokine receptors were induced irrespective of activation site. The majority of activated CD8 T cells expressed CXCR3, with one subset additionally expressing P-selectin ligand, and another subset additionally expressing CCR3, CCR4, CCR5, CCR6, and CCR9. In the mesenteric lymph node, a fourth subset expressed CCR9 and CXCR3 in the absence of CCR5. Similar homing receptor profiles were induced in the same sites after localized vaccinia immunization. Homing receptor expression on CD8 T cells activated in vitro was distinct, revealing influences of both dendritic cells and the lymphoid microenvironment. Collectively, these results identify previously undescribed populations of activated CD8 T cells based on adhesion protein expression and coexpression of chemokine receptors that arise after activation in distinct secondary lymphoid organs.
Research on insulation detection of insulator strings with fuzzy logical reasoning method

Purpose – The purpose of this paper is to introduce the realizing process of the fuzzy logical reasoning method in relation to the insulation detection of insulator strings, especially about the establishment of the fuzzy relation matrix.Design/methodology/approach – Utilizing fuzzy logical reasoning method, the online fault diagnosis of the transmission line insulator strings can be realized efficiently, although the insulation status of the insulator strings is influenced by many factors and the relation between the measured electric parameters about the insulator with the degree of the deterioration is ambiguous.Findings – Utilizing the pattern recognition method to build the fuzzy relation matrix after choosing the probability of the corona current, the root‐mean‐square value and the peak value and the pulse frequency of the leakage current as the fuzzy operating input variables, using the fuzzy reasoning method to estimate the insulation status proves to be a practical approach.Practical implications.
Principal factors controlling biodiversity along an elevation gradient: Water, energy and their interaction

Variation in diversity is a well‐documented spatial pattern in biogeography, but an overarching climate‐based theory of diversity is lacking. We evaluate two models of species richness related to species‐richness‐energy theory. One is based on net primary production (NPP) or the more individuals hypothesis (MiH), and the other is a model based on water–energy dynamics (WED). We use taxa from three kingdoms along an extensive elevation‐temperature gradient. Both WED and NPP‐MiH are based on thermal energy, but the question is whether energy operates through regulating production and chemical (potential) energy only (NPP‐MiH), or if kinetic energy as regulator of available liquid water is needed (WED).
Forensic Document Examiners’ Skill in Distinguishing Between Natural and Disguised Handwriting Behaviors

Abstract: Disguised handwriting is problematic for forensic document examiners (FDEs) and attracts higher misleading and inconclusive rates on authorship opinions than does genuine writing (Found B, Rogers D, International Graphonomics Society, 2005). There are currently no published empirical data on FDEs’ expertise in distinguishing between natural and disguised writing behavior. This paper reports on the skill of FDEs for determining the writing process of 140 pairs of natural and disguised writings and compares their results with those of a control group of laypeople. A significant difference was found between the examiner and lay group. FDEs’ expertise is characterized by their conservatism, where FDEs express a higher proportion of inconclusive opinions (23.1% for FDEs compared to 8.4% for the control group). This leads to the FDEs expressing a smaller percentage of misleading responses when calling writings as either naturally written or disguised (4.3% for FDEs compared with 12.2% for the control group).
TDL-A Type Description Language for Constraint-Based Grammars

This paper presents TDL, a typed feature-based representation language and inference system. Type definitions in TDL consist of type and feature constraints over the boolean counectives. TDL supports open-and closed-world reasoning over types and allows for partitions and incompatible types. Working with partially as well as with fully expanded types is possible. Efficient reasoning in TDL is accomplished through specialized modules.
Partial methylation of two adjacent adenosines in ribosomes from Euglena gracilis chloroplasts suggests evolutionary loss of an intermediate stage in the methyl-transfer reaction.

Bacterial, cytoplasmic and organellar ribosomes from a wide phylogenetic spectrum of organisms have a characteristic m6(2)Am6(2)A structure near the 3' end of the RNA of the small ribosomal subunit (SSU). We have studied one of the few exceptions to this extremely conserved post-transcriptionally modified sequence, i.e. dimethylation of only one of the two A's in chloroplasts from Euglena gracilis. It was established that only the A closest to the 5' end is dimethylated, the other one being unmodified. The methylation reaction was studied in vitro using ribosomes from a kasugamycin resistant mutant (ksgA) of Escherichia coli and purified methyl-transferase. Using limited amounts of the methyl donor S-adenosylmethionine (SAM) a partial level of methylation (50% of control) was attained. It is shown that in this case the 3' proximal A is dimethylated while the other is not. This suggests that dimethylation takes place in two successive stages. Apparently in E. gracilis chloroplasts the first stage of methylation does not occur.
Idiopathic Arterial Calcification in Infancy

Arterial calcification has been known to occur in infancy since the early reports of Durante (1899) and Bryant and White (1901). In many instances arterial lesions have been associated with renal disease, hypervitaminosis-D or congenital anomalies of the heart and great vessels, but more rarely there has been no demonstrable primary disease. About 50 cases of this idiopathic type of arterial calcification in infancy have now been described and the published material has been comprehensively reviewed on several occasions (Field, 1946; Stryker, 1946; Moran and Becker, 1959). Nevertheless, our knowledge of the condition has not progressed beyond the descriptive stage, and hypotheses of its aetiology show no advance on those put forward by Stryker in 1946. From the standpoint of morbid anatomy and histology the cases described have been carbon-copies of each other and the various published photographs of the lesions could be interchanged without loss of context. Clinically, too, the cases have often been similar with sudden death as a usual occurrence. Although idiopathic arterial calcification in infancy is not well known it is probably not as rare as the small number of recorded cases suggests. In addition to the two cases described here we know of two others that have not been recorded. We think, therefore, that this report is worth while, in the hope that wider recognition of the disease may lead to diagnosis during life and the institution of clinical and biochemical studies without which little further progress in understanding the disease is likely.
Insular Dysfunction Reflects Altered Between-Network Connectivity and Severity of Negative Symptoms in Schizophrenia during Psychotic Remission

Schizophrenia is characterized by aberrant intrinsic functional connectivity (iFC) within and between intrinsic connectivity networks (ICNs), including the Default Mode- (DMN), Salience- (SN), and Central Executive Network (CEN). The anterior insula (AI) of the SN has been demonstrated to modulate DMN/CEN interactions. Recently, we found that the dependence of DMN/CEN interactions on SN’s right AI activity is altered in patients with schizophrenia in acute psychosis and related to psychotic symptoms, indicating a link between aberrant AI, DMN, CEN, and psychosis. However, since structural alterations of the insula are also present during psychotic remission and associated with negative symptoms, impaired AI interaction might be relevant even for psychotic remission and corresponding symptoms. Twelve patients with schizophrenia during psychotic remission (SR) and 12 healthy controls were assessed using resting-state fMRI and psychometric examination. High-model-order independent component analysis of fMRI data revealed ICNs including DMN, SN, and CEN. Scores of iFC within (intra-iFC) and between (inter-iFC) distinct subsystems of the DMN, SN, and CEN were calculated, compared between groups and correlated with the severity of symptoms. Intra-iFC was altered in patients’ SN, DMN, and CEN, including decreased intra-iFC in the left AI within the SN. Patients’ inter-iFC between SN and CEN was increased and correlated with the severity of negative symptoms. Furthermore, decreased intra-iFC of the left AI correlated with both severity of negative symptoms and increased inter-iFC between SN and CEN. Our result provides first evidence for a relationship between AI dysfunction and altered between-network interactions in schizophrenia during psychotic remission, which is related to the severity of negative symptoms. Together with our previous results, data suggest specific SN/DMN/CEN reorganization in schizophrenia with distinct insular pathways for distinct symptom dimensions.
Visual Representations of Sexual Violence in Online News Outlets

To study visual representations of sexual violence, photographs accompanying German Internet news articles that appeared between January 2013 and March 2015 (N = 42) were subjected to thematic analysis. Two main themes, consisting of several sub-themes, emerged from the data. The first theme was “rape myths,” illustrating a stereotypical view of sexual violence. It consisted of three sub-themes: “beauty standards,” referring to the fact that all women in our sample fit western beauty standards, “physical violence,” as most images implied some form of physical violence, and finally “location,” suggesting that rape only happens in secluded outdoor areas. These findings suggest that the images from our sample perpetuate certain rape myths. The second theme was “portrayal of victimhood,” referring to the way victims of sexual violence were portrayed in photographs. The analysis of the sub-theme “passivity” showed that these portrayals fit a certain stereotype: the women were shown to be weak and helpless rather than individuals with agency and able to leave their status as a victim. Further sub-themes were “background,” “organization of space,” “camera perspective,” and “lighting. ” We discuss these findings in relation to possibly reinforcing rape myths in society and as an issue in creating a biased perception of women who have experienced sexual violence.
Melatonin modulates the expression of Bcl-2 family proteins in liver after thermal injury in rats

Melatonin, the principal secretory product of the pineal gland, functions as a potent antioxidant and free radical scavenger. Additionally, the antiapoptotic effect of melatonin has been observed both in vivo and in vitro. The aim of this study was to investigate the protective effects of melatonin against burn-induced injury in rat liver and whether these changes were associated with oxidative stress and changes in the expression of apoptosis related genes Bcl-2 and Bax. Melatonin (10 mg/kg, i.p.) was applied immediately after 30% of total body surface area (TBSA) burns of male Wistar rats. Malondialdehyde (MDA) as marker of oxidative stress and tumor necrosis factor (TNF-α) as inflammatory marker were assayed by biochemical methods. The hepatic apoptosis related genes Bcl-2 and Bax using light immunоchistochemistry were investigated, too. Hepatic TNF-α and MDA levels were increased significantly following severe burn. Thermal trauma increased the Bax expression without any changes of anti-apoptotic Bcl-2 protein in sinusoidal endothelial cells (SECs) of burn-treated animals compared with the control group animals as well as elevated ratio Bax/Bcl-2 suggesting the susceptibility of these cells to apoptosis. Melatonin significantly decreased the MDA and TNF-α levels in the liver tissue. It decreased also expression of Bax, increased expression of Bcl-2 and reduced Bax/Bcl-2 ratio. In conclusion, experimental data show that melatonin modulates the expression of Bcl-2 family proteins by increasing anti-apoptotic Bcl-2, inhibits apoptosis and restricts the burn-induced damage.
The Structure of Interurban Traffic: A Weighted Network Analysis

We study the structure of the network representing the interurban commuting traffic of the Sardinia region, Italy, which amounts to 375 municipalities and 1600 000 inhabitants. We use a weighted network representation in which vertices correspond to towns and the edges correspond to the actual commuting flows among those towns. We characterize quantitatively both the topological and weighted properties of the resulting network. Interestingly, the statistical properties of the commuting traffic exhibit complex features and nontrivial relations with the underlying topology. We characterize quantitatively the traffic backbone among large cities and we give evidence for a very high heterogeneity of the commuter flows around large cities. We also discuss the interplay between the topological and dynamical properties of the network as well as their relation with sociodemographic variables such as population and monthly income. This analysis may be useful at various stages in environmental planning and provides analytical tools for a wide spectrum of applications ranging from impact evaluation to decision making and planning support.