Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of exercise-intensity on skeletal muscle stress kinase and insulin protein signaling

Background Stress and mitogen activated protein kinase (SAPK) signaling play an important role in glucose homeostasis and the physiological adaptation to exercise. However, the effects of acute high-intensity interval exercise (HIIE) and sprint interval exercise (SIE) on activation of these signaling pathways are unclear. Methods Eight young and recreationally active adults performed a single cycling session of HIIE (5 x 4 minutes at 75% Wmax), SIE (4 x 30 second Wingate sprints), and continuous moderate-intensity exercise work-matched to HIIE (CMIE; 30 minutes at 50% of Wmax), separated by a minimum of 1 week. Skeletal muscle SAPK and insulin protein signaling were measured immediately, and 3 hours after exercise. Results SIE elicited greater skeletal muscle NF-κB p65 phosphorylation immediately after exercise (SIE: ~40%; HIIE: ~4%; CMIE; ~13%; p < 0.05) compared to HIIE and CMIE. AS160Ser588 phosphorylation decreased immediately after HIIE (~-27%; p < 0.05), and decreased to the greatest extent immediately after SIE (~-60%; p < 0.05). Skeletal muscle JNK (~42%; p < 0.05) and p38 MAPK (~171%; p < 0.05) phosphorylation increased, and skeletal muscle AktSer473 phosphorylation (~-32%; p < 0.05) decreased, to a similar extent immediately after all exercise protocols. AS160Ser588 phosphorylation was similar to baseline three hours after SIE (~-12%; p > 0.05), remained lower 3 hours after HIIE (~-34%; p < 0.05), and decreased 3 hours after CMIE (~-33%; p < 0.05). Conclusion Despite consisting of less total work than CMIE and HIIE, SIE proved to be an effective stimulus for the activation of stress protein kinase signaling pathways linked to exercise-mediated adaptation of skeletal muscle. Furthermore, post-exercise AS160Ser588 phosphorylation decreased in an exercise-intensity and post-exercise time-course dependent manner.
Defining Composite Configurable SaaS Application Packages Using SCA, Variability Descriptors and Multi-tenancy Patterns

Currently, several vendors and projects are building proprietary SaaS platforms where more and more applications are hosted in a Software as a Service business model. However, these proprietary platforms prevent that applications offered by different SaaS application vendors can be easily reused on the platforms offered by the different SaaS hosting providers. In this paper we describe a package format for composite configurable SaaS application packages for applications developed following a service oriented architecture. We show how the service component architecture (SCA) can be extended with variability descriptors and SaaS multi-tenancy patterns to package and deploy multi- tenant aware configurable composite SaaS applications.
The Impact of Relational Variables on Export Performance: An Empirical Investigation in Australia and the UK

The impact of relational variables on export performance is tested across two countries—the UK and Australia. The key drivers are shown to he two kinds of commitment: to the market (country), and to the relationship with the distributor, both of which begin with experiential data gathering, or social learning. The constructs are operationalised and tested with data from the early stages of export ventures by small and medium sized enterprises (SMEs). The results support the importance of social learning and relational variables to export performance.
Elasticity of Substitution between Capital and Labor and its Applications to Growth and Development

This paper estimates the elasticity of substitution of an aggregate production function. The estimating equation is derived from the steady state of a neoclassical growth model. The data comes from the PWT in which different countries face different relative prices of the investment good and exhibit different investment-output ratios. Then, taking advantage of this variation we estimate the long-run elasticity of substitution. Using various estimation techniques, we find that the elasticity of substitution is 0.7, which is lower than the elasticity, 1, that is traditionally used in macro-development exercises. We show that this lower elasticity reinforces the power of the neoclassical model to explain income differences across countries as coming from differential distortions.
International Economic Interdependence and Exchange�?Rate Adjustment Under Persistent Stagnation

type="main"> Using a two-country, two-commodity dynamic optimization model with general homothetic preference for the commodities, this paper examines the effects of a tariff and a quota on consumption and employment in the case where persistent unemployment arises due to a liquidity trap. A trade restriction improves the current account, which causes the home currency to appreciate and harms the competitiveness of home firms. Therefore, home employment and consumption decrease while foreign employment and consumption increase. Tariff-quota equivalence is found to be valid. Preference, technological and policy parameter changes that improve the current account in general worsen home unemployment.
Is the Geographic Range of Mangrove Forests in the Conterminous United States Really Expanding?

Changes in the distribution and abundance of mangrove species within and outside of their historic geographic range can have profound consequences in the provision of ecosystem goods and services they provide. Mangroves in the conterminous United States (CONUS) are believed to be expanding poleward (north) due to decreases in the frequency and severity of extreme cold events, while sea level rise is a factor often implicated in the landward expansion of mangroves locally. We used ~35 years of satellite imagery and in situ observations for CONUS and report that: (i) poleward expansion of mangrove forest is inconclusive, and may have stalled for now, and (ii) landward expansion is actively occurring within the historical northernmost limit. We revealed that the northernmost latitudinal limit of mangrove forests along the east and west coasts of Florida, in addition to Louisiana and Texas has not systematically expanded toward the pole. Mangrove area, however, expanded by 4.3% from 1980 to 2015 within the historic northernmost boundary, with the highest percentage of change in Texas and southern Florida. Several confounding factors such as sea level rise, absence or presence of sub-freezing temperatures, land use change, impoundment/dredging, changing hydrology, fire, storm, sedimentation and erosion, and mangrove planting are responsible for the change. Besides, sea level rise, relatively milder winters and the absence of sub-freezing temperatures in recent decades may be enabling the expansion locally. The results highlight the complex set of forcings acting on the northerly extent of mangroves and emphasize the need for long-term monitoring as this system increases in importance as a means to adapt to rising oceans and mitigate the effects of increased atmospheric CO2.
Adjusted State Teacher Salaries and the Decision to Teach

Using the 3-year sample of the American Community Survey (ACS) for 2009 to 2011, we compute public school teacher salaries for comparison across U.S. states. Teacher salaries are adjusted for state differences in teacher characteristics, cost of living, household amenity attractiveness and federal tax rates. Salaries of non-teaching college graduates, defined as those with occupations outside of education, are used to adjust for state household amenity attractiveness. We then find that state differences in federal tax-adjusted teacher salaries relative those of other college graduates significantly affects the share of education majors that are employed as teachers at the time of the survey.
Export Dynamics in Large Devaluations

This paper studies export dynamics in emerging markets following large devaluations. We document two main features of exports that are puzzling for standard trade models. First, given the change in relative prices, exports tend to grow gradually following a devaluation. Second, high interest rates tend to suppress exports. To address these features of export dynamics, we embed a model of endogenous export participation due to sunk and per period export costs into an otherwise standard small open economy. In response to shocks to productivity, interest rates, and the discount factor, we find the model can capture the salient features of export dynamics documented. At the aggregate level, the features giving rise to sluggish export dynamics leading to more gradual net export dynamics, sharper contractions in output, and endogenous declines in labor productivity.
New Crosstalk Avoidance Codes Based on a Novel Pattern Classification

The crosstalk delay associated with global on-chip interconnects becomes more severe in deep submicrometer technology, and hence can greatly affect the overall system performance. Based on a delay model proposed by Sotiriadis , transition patterns over a bus can be classified according to their delays. Using this classification, crosstalk avoidance codes (CACs) have been proposed to alleviate the crosstalk delays by restricting the transition patterns on a bus. In this paper, we first propose a new classification of transition patterns, and then devise a new family of CACs based on this classification. In comparison to the previous classification, our classification has more classes and the delays of its classes do not overlap, both leading to more accurate control of delays. Our new family of CACs includes some previously proposed codes as well as new codes with reduced delays and improved throughput. Thus, this new family of CACs provides a wider variety of tradeoffs between bus delay and efficiency. Finally, since our analytical approach to the classification and CACs treats the technology-dependent parameters as variables, our approach can be easily adapted to a wide variety of technologies.
Smoking and Hand Dermatitis in the United States Adult Population

Background Hand dermatitis is a common chronic relapsing skin disease resulting from a variety of causes, including endogenous predisposition and environmental exposures to irritants and allergens. Lifestyle factors such as smoking have been implicated in hand dermatitis. Objective To evaluate the association between tobacco exposure and hand dermatitis using the 2003~2004 National Health and Nutrition Examination Survey (NHANES) database. Methods Data were retrieved and analyzed from 1,301 participants, aged 20~59 years, from the 2003~2004 NHANES questionnaire study who completed health examination and blood tests. Diagnosis of hand dermatitis was based on standardized photographs of the dorsal and palmar views of the hands read by two dermatologists. Results There were 38 diagnosed cases of active hand dermatitis out of the 1,301 study participants (2.9%). Heavy smokers (>15 g tobacco daily) were 5.11 times more likely to have active hand dermatitis (odds ratio [OR], 5.11; 95% confidence interval [CI], 1.39~18.88; p=0.014). Those with serum cotinine >3 ng/ml were also more likely to have active hand dermatitis, compared with those with serum cotinine ≤3 ng/ml (OR, 2.50; 95% CI, 1.26~4.95; p=0.007). After adjusting for confounding factors such as age, atopic diathesis, occupational groups, and physical activity, the association between tobacco exposure and active hand dermatitis remained significant. Conclusion Smoking has a significant association with the presence of active hand dermatitis. It is important to consider smoking cessation as part of management of hand dermatitis.
2009 2nd International Conference on Power Electronics and Intelligent Transportation System a Novel Control Strategy of Power Converter Used to Direct Driven Permanent Magnet Wind Power Generation System

Fig. I Controlstructure of converter deviceused to directdriven permanent magnetwind powergeneration system Where p is the air density, A is the area swept out by the turbine blades, V w is the wind velocity, and cp is the power II. WIND TURBINE CHARACTERISTICS According to Betz[3],the mechanical power captured by wind turbine is expressed as: (1) Gr i d-s i d ", ccnvcrt cr G('n (,l"a t o l'-s i d e co nvcrt er become the research focus. The paper focuses on the control strategy of back-to-back PWM power converter used to direct-drive permanent magnet wind power system. The power converter control comprises the generator side converter control and the grid side converter control. The voltage space vector PWM in field-oriented control adopted in the control of the generator side converter. Through the field-oriented control, the highest efficiency of wind generator can be reached, the wind turbine is controlled to work at optimal tip speed ratio and to capture maximum wind energy. The control principle of grid-side converter, by which the DC-link voltage is kept constant, unit power factor gird connected inverter is realized, and current of grid-side is controlled to sine value, was designed on the basis of the grid voltage oriented vector control. The entire strategy of the direct drive wind turbine power generator illustrated in Fig. I. The simulation and experiments are carried out for the proposed control strategy. The simulation model of the system is developed in MATLAB/SlMULATION environment to analyze the performances of the novel control strategy. The simulation and experiments results verify that the proposed control strategy can not only extract maximum power under varying wind and regulate the voltage and frequency, but also shows very good dynamic and steady state performance. I. INTRODUCTION With the development of wind power technology in the worldwide , converter device used to wind power generation system has become one issue of global concerned problems. Because the power generated by wind generator is three-phase alternating current of variable voltage variable frequency, it must be transformed to that of fixed voltage and fixed frequency of 50Hz which is the same as that of grid voltage. Thus wind power which generated by the wind generator can parallel in the power grid. At present, there are mainly three kinds of generators are used in wind power system: induction generator, doubly fed induction generator(DFIG) and permanent magnet synchronous generator (PMSG)[I]. while a …
Organizing and managing personal electronic files

This article deals with the organization and management of the computer files handled by mechanical engineers on their personal computers. In engineering organizations, a wide variety of electronic files (documents) are necessary to support both business processes and the activities of design and manufacture. Whilst a large number of files and hence information is formally archived, a significant amount of additional information and knowledge resides in electronic files on personal computers. The widespread use of these personal information stores means that all information is retained. However, its reuse is problematic for all but the individual as a result of the naming and organization of the files. To begin to address this issue, a study of the use and current practices for managing personal electronic files is described. The study considers the fundamental classes of files handled by engineers and analyses the organization of these files across the personal computers of 40 participants. The study involves a questionnaire and an electronic audit. The results of these qualitative and quantitative elements are used to elicit an understanding of the practices and requirements of engineers for managing personal electronic files. A potential scheme for naming and organizing personal electronic files is discussed as one possible way to satisfy these requirements. The aim of the scheme is to balance the personal nature of data storage with the need for personal records to be shared with others to support knowledge reuse in engineering organizations. Although this article is concerned with mechanical engineers, the issues dealt with are relevant to knowledge-based industries and, in particular, teams of knowledge workers.
Using the interaction on social networks to predict real life friendship

In today's world, social networks are one of the most popular ways of communication. Communication and relations among people can be monitored based on interaction on social networks. The question is the exact meaning of this interaction and can the real life relationship be interpreted from interaction on social networks. In this study, we used the most popular social network Facebook with the aim of finding the correlation between the interaction among users on Facebook and friendship in real life. In this paper, we propose a model for calculating the weight of friendship among users of social networks based on their interactions on Facebook. The model takes into account the general significance of a particular form of interaction (like, comment, etc.) and the specific significance of this form of interaction for each user. Apart from creating a model for calculating the weight of friendship, in this paper, general significance ratio of each communication parameter was experimentally determined. The model was built and evaluated by searching intersection of two sets, a set of user's 10 best friends that he himself cited and a set of 10 best friends obtained using the proposed model. Average overlapping of these two sets was 70.9%. Additionally, the overlap level of these two sets for different demographic groups was analyzed.
Pulmonary arterial hypertension in idiopathic inflammatory myopathies

AbstractOccurrence of pulmonary arterial hypertension (PAH) in idiopathic inflammatory myopathies (IIMs) without extensive interstitial lung disease (ILD) has rarely been described in the medical literature. This study aimed to report all cases with association of PAH and IIM in the French Pulmonary Hypertension (PH) Registry, to identify IIM features associated with the presence of PAH, and to describe treatment modalities of these patients.All cases of IIM-PAH were retrieved from the French PH Registry, which gathers PH patients prospectively enrolled by 27 referral hospital centers across France. Patients were excluded if they had an extensive ILD or overlap syndrome. Characteristics of IIM-PAH patients were compared with a control group of IIM patients without PH.Among the 5223 PH patients in the Registry, 34 had a diagnosis of IIM. Among them, 3 IIM-PAH patients (2 females and 1 male) had no evidence of extensive ILD or overlap syndrome, and were included in this study. In these 3 patients, dermatomyositis (DM) was the only identified IIM. One patient had autoantibodies classically associated with IIM (anti-Ku). PAH had always developed after IIM onset, was severe in all cases, and led to a marked functional impairment.By pooling our cases with 6 patients previously reported in the literature, and comparing them with a control cohort of 35 IIM patients without PH, we identify several IIM characteristics possibly associated with PAH occurrence, including DM subtype (78% vs 46%; P = 0.02), skin involvement (P = 0.04), anti-SSA antibodies (P = 0.05), and peripheral microangiopathy (P = 0.06). Overall, IIM-PAH patients were managed by corticosteroids and/or immunosuppressants, either alone or combined with PAH therapy. Patients did not seem to respond to IIM treatment alone.Our study reports for the first time the rare but possible association of PAH and IIM in a large prospective PH Registry. In that setting, PAH seems associated with DM, skin involvement, peripheral microangiopathy, and anti-SSA positivity. The best therapeutic strategy for IIM-PAH remains to be defined.
What Do We Know about Tax Fraud?: An Overview of Recent Developments

This paper explores recent tendencies in the area of tax fraud. The paper stresses the importance of social norms and institutions and highlights the relevance of extending the standard theories of tax fraud which is based on a narrow deterrence concept. The paper also refers to underexplored topics that require further investigation such as the relevance of rewards, social interactions, and tax complexity stressing also the importance of moving more strongly into business tax fraud, exploring also the interactions within a firm. In addition, further work is also needed at the empirical level to better understand the causes and consequences of tax fraud. The review also shows the usefulness of applying a multi-faceted and interdisciplinary approach.
Dictionary and Image Recovery from Incomplete and Random Measurements

This paper tackles algorithmic and theoretical aspects of dictionary learning from incomplete and random block-wise image measurements and the performance of the adaptive dictionary for sparse image recovery. This problem is related to blind compressed sensing in which the sparsifying dictionary or basis is viewed as an unknown variable and subject to estimation during sparse recovery. However, unlike existing guarantees for a successful blind compressed sensing, our results do not rely on additional structural constraints on the learned dictionary or the measured signal. In particular, we rely on the spatial diversity of compressive measurements to guarantee that the solution is unique with a high probability. Moreover, our distinguishing goal is to measure and reduce the estimation error with respect to the ideal dictionary that is based on the complete image. Using recent results from random matrix theory, we show that applying a slightly modified dictionary learning algorithm over compressive measurements results in accurate estimation of the ideal dictionary for large-scale images. Empirically, we experiment with both space-invariant and space-varying sensing matrices and demonstrate the critical role of spatial diversity in measurements. Simulation results confirm that the presented algorithm outperforms the typical non-adaptive sparse recovery based on offline-learned universal dictionaries.
The Causes Of Financial Distress In Local Banks In Africa And Implications For Prudential Policy

This paper offers a critical survey of a strong globalization thesis that predicts a direct link from more open trade and investment regimes to faster economic growth in developing countries and income convergence across the global economy. Its examination of recent experience suggests that while in a more open and integrated world economy both the quantity and the quality of investment are influenced by external factors the forces driving capital accumulation retain strong domestic roots and remain open to the influence of various types of policy initiative.