Miracle-dz/UniFAR-FTUs huggingface dataset:
LIFETIME OF MEMORY FOR SELF-GENERATED INFORMATION

In experiments concerning the lifetime of short-term memory such as the classical BrownPeterson paradigm the to-be-memorized categorical information is presented via sensory stimuli. Therefore the memory could be based on retrieval from the long sensory store. We modified the Brown-Peterson paradigm such that subjects had to memorize internally generated material and prevented them from memorizing sensory information. The results show functions of correct answers over the retention interval that are similar to classical results. In the memory theory of Shiffrin and Schneider (1977) short-term memory is characterized as a process, being the activated part of long term memory, rather than a structural component. In addition to this Cowan (1984, 1995) proposed a framework in which also the long sensory stores are described as activated parts of long term memory. Because of the different lifetime of the trace, the short sensory stores are considered separate structural components in the model of Cowan. The long sensory stores of the different modalities and the categorical short-term memory should therefore be based on comparable processes in different codes/areas of the brain and hence yield equal or very much the same results in mnemonic experiments. Among the different paradigms that Cowan states as evidence for long sensory memory stores, the use of periodic noise (Guttman & Julesz, 1963; for a demonstration see www.periodic-noise.de) is most appropriate as it represents a very unstructured material (e.g. without any easily perceivable patterns like melodies, vowels, etc. as in other auditory stimuli) and therefore makes categorization of the to-be-memorized material difficult. The more categorization is prevented, the more certain sensory memory stores are utilized. The similarity of the long auditory memory system with classical parameters of the short-term memory system (e.g. lifetime, capacity, susceptibility to interference) could be shown in a study using periodic noise by Kaernbach (2001). Lifetime of sensory information was measured by determining the longest cycle length of periodic noise that could be detected. With very little training subjects were able to detect periodicity up to 10 and in some cases even 20 seconds. The collected data of Experiment 1 of this study are depicted in Figure 1. They are very similar to classical results obtained with Brown-Peterson paradigms (Brown, 1958, Peterson & Peterson, 1959).
Spontaneous Evolution in Bilirubin Levels Predicts Liver-Related Mortality in Patients with Alcoholic Hepatitis

The accurate prognostic stratification of alcoholic hepatitis (AH) is essential for individualized therapeutic decisions. The aim of this study was to develop a new prognostic model to predict liver-related mortality in Asian AH patients. We conducted a hospital-based, retrospective cohort study using 308 patients with AH between 1999 and 2011 (a derivation cohort) and 106 patients with AH between 2005 and 2012 (a validation cohort). The Cox proportional hazards model was constructed to select significant predictors of liver-related death from the derivation cohort. A new prognostic model was internally validated using a bootstrap sampling method. The discriminative performance of this new model was compared with those of other prognostic models using a concordance index in the validation cohort. Bilirubin, prothrombin time, creatinine, potassium at admission, and a spontaneous change in bilirubin levels from day 0 to day 7 (SCBL) were incorporated into a model for AH to grade the severity in an Asian patient cohort (MAGIC). For risk stratification, four risk groups were identified with cutoff scores of 29, 37, and 46 based on the different survival probabilities (P<0.001). In addition, MAGIC showed better discriminative performance for liver-related mortality than any other scoring system in the validation cohort. MAGIC can accurately predict liver-related mortality in Asian patients hospitalized for AH. Therefore, SCBL may help us decide whether patients with AH urgently require corticosteroid treatment.
Achieving Human Parity in Conversational Speech Recognition

Conversational speech recognition has served as a flagship speech recognition task since the release of the Switchboard corpus in the 1990s. In this paper, we measure the human error rate on the widely used NIST 2000 test set, and find that our latest automated system has reached human parity. The error rate of professional transcribers is 5.9% for the Switchboard portion of the data, in which newly acquainted pairs of people discuss an assigned topic, and 11.3% for the CallHome portion where friends and family members have open-ended conversations. In both cases, our automated system establishes a new state of the art, and edges past the human benchmark, achieving error rates of 5.8% and 11.0%, respectively. The key to our system's performance is the use of various convolutional and LSTM acoustic model architectures, combined with a novel spatial smoothing method and lattice-free MMI acoustic training, multiple recurrent neural network language modeling approaches, and a systematic use of system combination.
Gambling disorders, gambling type preferences, and psychiatric comorbidity among the Thai general population: Results of the 2013 National Mental Health Survey

Background and aims To estimate the prevalence of problem and pathological gambling, gender and age-group differences in gambling types, and comorbidities with other psychiatric disorders among the Thai general population. Methods Analysis was conducted on 4,727 participants of Thailand’s 2013 National Mental Health Survey, a multistage stratified cluster survey, using the Composite International Diagnostic Interview. Diagnoses of problem and pathological gambling and other psychiatric disorders were based on the DSM-IV-TR criteria with the following additional criteria for gamblers: more than 10 lifetime gambling episodes and a single year loss of at least 365 USD from gambling. Results The estimated lifetime prevalence rates of pathological and problem gambling were 0.90% [95% confidence interval (CI): 0.51–1.29] and 1.14% (95% CI: 0.58–1.70), respectively. The most popular type of gambling was playing lotteries [69.5%, standard error (SE) = 1.9], the prevalence of which was significantly higher among females and older age groups. The most common psychiatric disorders seen among pathological gamblers were alcohol abuse (57.4%), nicotine dependence (49.5%), and any drug use disorder (16.2%). Pathological gambling was highly prevalent among those who ever experienced major depressive episodes (5.5%), any drug dependence (5.1%), and intermittent explosive disorder (4.8%). The association between pathological gambling was strongest with a history of major depressive episode [adjusted odds ratio (AOR) = 10.4, 95% CI: 2.80–38.4]. Conclusion The study confirms the recognition of gambling disorders as a public health concern in Thailand and suggests a need for culturally specific preventive measures for pathological gamblers and those with a history of substance use disorders or major depression.
Isolation and Diversity Analysis of Resistance Gene Homologues from Switchgrass

Resistance gene homologs (RGHs) were isolated from the switchgrass variety Alamo by a combination of polymerase chain reaction and expressed sequence tag (EST) database mining. Fifty-eight RGHs were isolated by polymerase chain reaction and 295 RGHs were identified in 424,545 switchgrass ESTs. Four nucleotide binding site−leucine-rich repeat RGHs were selected to investigate RGH haplotypic diversity in seven switchgrass varieties chosen for their representation of a broad range of the switchgrass germplasm. Lowland and upland ecotypes were found to be less similar, even from nearby populations, than were more distant populations with similar growth environments. Most (83.5%) of the variability in these four RGHs was found to be attributable to the within-population component. The difference in nucleotide diversity between and within populations was observed to be small, whereas this diversity is maintained to similar degrees at both population and ecotype levels. The results also revealed that the analyzed RGHs were under positive selection in the studied switchgrass accessions. Intragenic recombination was detected in switchgrass RGHs, thereby demonstrating an active genetic process that has the potential to generate new resistance genes with new specificities that might act against newly-arising pathogen races.
Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel

Summary. Background: Strong P2Y12 blockade, as can be achieved with novel anti‐platelet agents such as prasugrel, has been shown in vitro to inhibit both ADP and thromboxane A2‐mediated pathways of platelet aggregation, calling into question the need for the concomitant use of aspirin. Objective: The present study investigated the hypothesis that aspirin provides little additional anti‐aggregatory effect in a group of healthy volunteers taking prasugrel. Study participants/methods: In all, 9 males, aged 18 to 40 years, enrolled into the 21‐day study. Prasugrel was loaded at 60 mg on day 1 and maintained at 10 mg until day 21. At day 8, aspirin 75 mg was introduced and the dose increased to 300 mg on day 15. On days 0, 7, 14 and 21, platelet function was assessed by aggregometry, response to treatments was determined by VerifyNow™ and urine samples were collected for quantification of prostanoid metabolites. Results: At day 7, aggregation responses to a range of platelet agonists were reduced and there was only a small further inhibition of aggregation to TRAP‐6, collagen and epinephrine at days 14 and 21, when aspirin was included with prasugrel. Urinary prostanoid metabolites were unaffected by prasugrel, and were reduced by the addition of aspirin, independent of dose. Conclusions: In healthy volunteers, prasugrel produces a strong anti‐aggregatory effect, which is little enhanced by the addition of aspirin. The addition of aspirin as a dual‐therapy with potent P2Y12 receptor inhibitors warrants further investigation.
Content Aggregation by Platforms: The Case of the News Media

The digitization of content has led to the emergence of platforms that draw information from multiple sources. Policymakers are concerned that these new platforms threaten incentives for the production of original content. As a result, policymakers are contemplating regulations that would force aggregation platforms to pay or require an explicit "opt-in" for content providers. To understand the possible consequences and underlying rationale of such laws, we explore whether aggregation of content by a single platform encourages users to "skim" content or to investigate in depth. We study a contract dispute that led a major aggregator to remove information from a major content provider. We find that after the removal, users were less likely to investigate additional, related content in depth, particularly sources that were horizontally or vertically differentiated.
Heat Shock Protein 27 Is Spatially Distributed in the Human Placenta and Decreased during Labor

Placental oxidative stress is a feature of human labor. Heat shock proteins (HSPs) play a key role in cellular stress. We hypothesized that placental expression of the small HSP 27 would be altered during labor and expression would vary in different regions of the placenta. Six women in labor who delivered vaginally and 6 women not in labor, who were delivered by Cesarean section, were recruited. Four equally spaced pieces were sampled from the inner, middle and outer regions of each placenta (total 12 samples per placenta). HSP 27 expression was investigated by Western blot analysis and RT-PCR. For non-labor, there was less HSP 27 protein in the inner placenta region compared with both the middle region (p<0.05) and outer region (p<0.05). For labor, there was also less HSP 27 protein in the inner region compared with both the middle (p<0.02) and outer region (p<0.01). When the 3 regions of the placenta were compared for non-labor versus labor there was less HSP 27 in the labor group at both the inner (p<0.05) and middle regions (p<0.005) compared to non-labor. Similar to HSP 27 protein, there was less HSP 27 mRNA in the labor group in both the inner region (p<0.05) and middle region (p<0.02) compared to non-labor. This study suggests that placental HSP 27 may play a role in labor and is spatially controlled. The results have important implications for how data obtained from studies in the placenta can be influenced by sampling methods.
Dishabituation and sensitization emerge as separate processes during development in Aplysia

Until recently, dishabituation and sensitization have commonly been considered to reflect a unitary process: Sensitization refers to a general facilitation produced by strong or noxious stimuli that enhances subsequent responding; dishabituation has been thought to represent a special instance of sensitization in which the facilitation is simply superimposed on a habituated response level. The unitary process hypothesis was based on the observation that both decremented and nondecremented responses are facilitated by a common noxious or strong stimulus. However, this observation does not rule out the possibility that dishabituation and sensitization could reflect separate processes that are activated in parallel by a strong stimulus. Recent cellular experiments by Hochner et al. (1986) suggest that this, in fact, occurs in the sensory neurons of the gill withdrawal reflex in Aplysia. A developmental analysis of learning in the marine mollusc Aplysia permits a direct behavioral test of this hypothesis. If dishabituation and sensitization reflect a unitary process then they should emerge at the same time ontogenetically. On the other hand, if they reflect different processes, then they might emerge according to different ontogenetic timetables. In the present study we examined the temporal emergence of dishabituation and sensitization in the defensive siphon withdrawal reflex in 3 stages of juvenile Aplysia: stage 11, early stage 12, and late stage 12. Animals received one of 2 kinds of training: Dishabituation training, in which the effect of strong tail shock on habituated responses were observed, and Sensitization training, in which the effect of strong tail shock on nondecremented responses was observed. We found that, while dishabituation was present in all stages examined, sensitization did not emerge until several weeks later, in late stage 12. These results were confirmed and extended in a group of animals that were tested twice: first in stage 11, when they showed no sensitization, and again 13 weeks later, in late stage 12, when they then showed significant sensitization. Our analysis of nondecremented responses prior to the emergence of sensitization also revealed an unexpected inhibitory component of tail shock that produces reflex depression. Moreover, there was a clear progression in the net effects of tail shock during development: reflex depression was produced in stages 11 and early stage 12, followed by a transition to reflex facilitation (sensitization) in late stage 12. Finally, when sensitization emerged in late stage 12, the process of dishabituation showed a significant increase compared with previous developmental stages.
When Different Types of Education Matter

Using longitudinal data for a nationally representative sample of ninth graders in South Korea, we examine socioeconomic differences in the likelihood of making transitions into different types of high school and college with a goal of testing the validity of the effectively maintained inequality hypothesis. We find significant socioeconomic disparities in the likelihood of attending an academic high school and a 4-year university. However, the predicted probabilities suggest that even disadvantaged students typically choose an academic high school relative to a vocational high school. Furthermore, although disadvantaged students likely end up with a 2-year junior college, those disadvantaged students graduating from an academic high school typically choose a 4-year university, after controlling for academic achievement and other variables. We discuss the relevance of the effectively maintained inequality hypothesis for South Korea and broad implications for elsewhere where postsecondary education is increasingly available for the majority of population.
Local best particle swarm optimization for partitioning data clustering

This paper proposes a new method for partitioning data clustering using PSO. The Proposed methods LPSOC designed for hard clusters. LPSOC alleviate some of the drawbacks of traditional algorithms and the state-of-the-art PSO clustering algorithm. Population-based algorithms such as PSO is less sensitive to initial condition than other algorithms such as K-means since search starts from multiple positions. The proposed algorithm LPSOC is less susceptible to local minima than K-means or even gbest version of PSO. In gbest PSO, all centroids are encoded in a single particle. Thus, the global best particle is a complete solution to the problem because its encoding contains the best position found for the centroids of all clusters. We used the local version of PSO in LPOSC. LPSOC uses a neighborhood of particles for optimizing the position of each cluster centroid. The whole swarm represents a solution to the clustering problem. This representation is far less computationally expensive than standard gbest version. The LPSOC is tested using six datasets from different domains to measure its performance fairly. LPOSC is compared with standard PSO for clustering and K-means. The results assure that the proposed method is very promising.
Understanding the impact of code and process metrics on post-release defects: a case study on the Eclipse project

Research studying the quality of software applications continues to grow rapidly with researchers building regression models that combine a large number of metrics. However, these models are hard to deploy in practice due to the cost associated with collecting all the needed metrics, the complexity of the models and the black box nature of the models. For example, techniques such as PCA merge a large number of metrics into composite metrics that are no longer easy to explain. In this paper, we use a statistical approach recently proposed by Cataldo et al. to create explainable regression models. A case study on the Eclipse open source project shows that only 4 out of the 34 code and process metrics impacts the likelihood of finding a post-release defect. In addition, our approach is able to quantify the impact of these metrics on the likelihood of finding post-release defects. Finally, we demonstrate that our simple models achieve comparable performance over more complex PCA-based models while providing practitioners with intuitive explanations for its predictions.
Reduced visual surround suppression in schizophrenia shown by measuring contrast detection thresholds

Visual perception in schizophrenia is attracting a broad interest given the deep knowledge that we have about the visual system in healthy populations. One example is the class of effects known collectively as visual surround suppression. For example, the visibility of a grating located in the visual periphery is impaired by the presence of a surrounding grating of the same spatial frequency and orientation. Previous studies have suggested abnormal visual surround suppression in patients with schizophrenia. Given that schizophrenia patients have cortical alterations including hypofunction of NMDA receptors and reduced concentration of GABA neurotransmitter, which affect lateral inhibitory connections, then they should be relatively better than controls at detecting visual stimuli that are usually suppressed. We tested this hypothesis by measuring contrast detection thresholds using a new stimulus configuration. We tested two groups: 21 schizophrenia patients and 24 healthy subjects. Thresholds were obtained using Bayesian staircases in a four-alternative forced-choice detection task where the target was a grating within a 3∘ Butterworth window that appeared in one of four possible positions at 5∘ eccentricity. We compared three conditions, (a) target with no-surround, (b) target embedded within a surrounding grating of 20∘ diameter and 25% contrast with same spatial frequency and orthogonal orientation, and (c) target embedded within a surrounding grating with parallel (same) orientation. Previous results with healthy populations have shown that contrast thresholds are lower for orthogonal and no-surround (NS) conditions than for parallel surround (PS). The log-ratios between parallel and NS thresholds are used as an index quantifying visual surround suppression. Patients performed poorly compared to controls in the NS and orthogonal-surround conditions. However, they performed as well as controls when the surround was parallel, resulting in significantly lower suppression indices in patients. To examine whether the difference in suppression was driven by the lower NS thresholds for controls, we examined a matched subgroup of controls and patients, selected to have similar thresholds in the NS condition. Patients performed significantly better in the PS condition than controls. This analysis therefore indicates that a PS raised contrast thresholds less in patients than in controls. Our results support the hypothesis that inhibitory connections in early visual cortex are impaired in schizophrenia patients.
The Effect of Enclothed Cognition on Empathic Responses and Helping Behavior

Abstract. Based on the enclothed cognition framework, we tested whether the physical experience of wearing a tunic and identifying it with a nursing scrub may enhance empathic and helping responding, compared to the solely physical experience of wearing the scrub or associating with its symbolic meaning. Results of Study 1 (United Kingdom; n = 150) showed that participants who wore a tunic and identified it with a nursing scrub reported higher empathic concern and helped more in a punctual scenario, compared to the other two conditions. Results of Study 2 (Spain; n = 100) supported findings from Study 1 and showed that participants who wore a tunic and identified it with a nursing scrub volunteered more hours and showed higher response latency for altruistic motivation relevant words. Thus, the current research supports the enclothed cognition framework and shows that it also affects vicarious emotions and prosocial behavior.
An EPG study of lingual errors in adults with acquired aphasia: Implications for models of speech production.

For a model of speech production to be comprehensive it must be able to account for both disordered and normal speech. The study of disordered speech often relies on perceptual judgements which are not always accurate enough representations of the speech process for such models. Perceptual judgements often encourage categorical decisions such as alveolar versus velar plosive which may not reflect articulatory reality. Evidence from EPG studies has identified non categorical errors, for example, so-called "misdirected articulatory gestures" (MAGs) which appear to be characteristic of aphasic speech. These involve distinctive lingual/palatal contacts which often remain undetected auditorily. For example, analysis of EPG data reveals cases where a perceived alveolar plosive may in reality be a double alveolar/velar articulation due to the presence of a velar MAG. This paper describes MAGs in ten aphasics and provides an explanation for them in relation to a modified model of interactive spreading activation.