Miracle-dz/UniFAR-FTUs huggingface dataset:
Two Languages in the Classroom: The Inconsistency Between National and Local Objectives of Formal Education in Cyprus

This study investigates the complex interplay between national and local objectives of formal education in the bidialectal context of Cyprus. Even though the state and the Ministry of Education and Culture urge teachers to employ the standard language variety in education, the dialect is often used as a medium of interaction and even instruction during class time. Specifically, this study examines in which communicative interactions in the classroom language becomes a salient feature of the interaction and whether patterns arise as regards the factors that influence teachers' and learners' selection of one or the other language variety. Data collected from kindergarten, primary, and secondary education via class observations suggest that teachers' differing language practices are largely influenced by the subject area they teach and more often than not inconsistencies arise in connection with the state's national objectives of formal education and the school's or teacher's local objectives in the classroom.
Connecting Work—Family Policies to Supportive Work Environments

This research provides a theory-driven approach to study the relationship between the availability of work—family policies and family-supportive organization perceptions (FSOPs) and supervisory support perceptions (SSPs). At-risk family characteristics, which are characteristics that potentially affect work—family conflict such as a young child in the home, are investigated as a moderator of the proposed relationships. Findings substantiate positive relationships between the availability of work—family policies and FSOPs and SSPs; in addition, at-risk family characteristics are found to strengthen the relationship between work—family policies and SSPs. FSOPs and SSPs are also examined as mediators of the relationship between work—family policies and employee outcomes of intention to turnover, job satisfaction, and job burnout. Findings partially support FSOPs and SSPs as having mediating influences in the work—family policies and work attitudes relationship.
Facilitating Elaborative Learning Through Guided Student-Generated Questioning

A guided learner-generated questioning strategy was designed to prompt learners to elaborate on new material in an effort to facilitate their understanding of that material. In a series of studies conducted in naturalistic settings, the relative effectiveness of this strategy was compared with that of several other learning and study strategies for high school and college students learning regular course content presented in classroom lectures. Findings from these studies indicate that the guided questioning strategy facilitated learning by prompting students to generate specific thought-provoking questions pertaining to the material to be learned, and those questions in turn elicited relevant explanations. The characteristics of the questioning strategy that accounts for these effects were the critical-thinking nature of the question prompts and the high degree of learner autonomy within the structure of the strategy. A model of the components and processes of the strategy is included.
Land of ‘My 9’: Welsh–English Bilingual Girls Creating Spaces to Explore Identity

Based on ongoing research into the literacy practices of bilingual girls from different UK communities, this article focuses on the experiences of 11‐ to 13‐year‐old Welsh–English bilingual girls in Wales. Examples of the girls' talk about their bilingual lives are explored within the social, political, educational and literary context of the Welsh language today. The position of these young Welsh speakers within both the wider dominant, English language context and that of the Welsh language and culture proves to be riven with paradox. However, the girls make creative use of their situation to explore and demonstrate their own identities. One way in which this is evident is in their use of electronic text, and examples are drawn here of their use of personal websites and Instant Messaging in order to provide an insight into their experience.
Antioxidant Status and Oxidative Stress in Primary Open Angle Glaucoma and Pseudoexfoliative Glaucoma

Purpose: The aim of this study was to establish the antioxidant status and oxidative stress in patients with primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEG). Methods: Serum levels of total antioxidant capacity (TAC) and superoxide dismutase (SOD) as indicators of antioxidant status; and total oxidant status (TOS), nitric oxide (NO), protein carbonyl (PC), and malondialdehyde (MDA) as indicators of oxidative stress were measured from the blood samples of patients with POAG (n = 23), PEG (n = 24) and healthy control subjects (n = 19) by spectrophotometry. Results: Mean TAC level was 0.6 ± 0.1 mmol/L in the POAG group; 0.5 ± 0.1 mmol/L in the PEG group and 1.2 ± 0.3 mmol/L in the control group (p = 0.001). Mean SOD level was 13 ± 0.5 mg/L in the POAG group, 11.6 ± 0.2 mg/L in the PEG group and 9.4 ± 0.6 mg/L in the control group (p = 0.001). Mean TOS level was 19.6 ± 2.6 μmol/L in the POAG group, 21.2 ± 4.2 μmol/L in the PEG group and 15.1 ± 7 μmol/L in the control group (p = 0.001). Mean NO level was 74.3 ± 14.4 µmol/L in the POAG group, 66.1 ± 8.1 µmol/L in the PEG group and 62.3 ± 13.5 µmol/L in the control group (p = 0.005). Mean PC level was 641.5 ± 102.5 nmol/mg in the POAG group, 988.3 ± 214.7 nmol/mg in the PEG group and 654.4 ± 150.7 nmol/mg in the control group (p = 0.001). Mean MDA level was 1.9 ± 0.2 µmol/L in the POAG group, 1.7 ± 0.4 µmol/L in the PEG group and 1.1 ± 0.2 µmol/L in the control group (p = 0.001). Conclusion: The findings of the present study are potentially of significance and add to the growing body of evidence for oxidative stress in POAG and PEG. Decreased antioxidant defense and increased oxidative stress system may play an important role in the pathogenesis of POAG and PEG.
Securities Lending, Shorting, and Pricing

We present a model of asset valuation in which short-selling is achieved by searching for security lenders and by bargaining over the terms of the lending fee. If lendable securities are difficult to locate, then the price of the security is initially elevated, and expected to decline over time. This price decline is to be anticipated, for example, after an initial public offering (IPO), among other cases, and is increasing in the degree of heterogeneity of beliefs of investors about the likely future value of the security. The prospect of lending fees may push the initial price of a security above even the most optimistic buyer's valuation of the security's future dividends. A higher price can thus be obtained with some shorting than if shorting is disallowed.
Use of Recombinant Antigens for Sensitive Serodiagnosis of American Tegumentary Leishmaniasis Caused by Different Leishmania Species

ABSTRACT American tegumentary leishmaniasis (ATL) (also known as cutaneous leishmaniasis [CL]) is caused by various species of protozoa of the genus Leishmania. The diagnosis is achieved on a clinical, epidemiological, and pathological basis, supported by positive parasitological exams and demonstration of leishmanin delayed-type hypersensitivity. Serological assays are not routinely used in the diagnosis because many are considered to have low sensitivity and the particular Leishmania species causing the disease can lead to variable performance. In the present study, we generated recombinant versions of two highly conserved Leishmania proteins, Leishmania (Viannia) braziliensis-derived Lb8E and Lb6H, and evaluated both in enzyme-linked immunosorbent assays (ELISA). Recombinant Lb6H (rLb6H) had better performance and reacted with 100.0% of the ATL and 89.4% of the VL samples. These reactions with rLb6H were highly specific (98.5%) when compared against those for samples from healthy control individuals. We then assessed rLb6H against sera from ATL patients infected with different species of Leishmania prevalent in Brazil [Leishmania (Leishmania) amazonensis, L. (Viannia) braziliensis, and L. (V.) guyanensis] and samples from patients with other infectious diseases. In analyses of 500 sera, ELISA using rLb6H detected all 219 ATL samples (sensitivity of 100.0%) with an overall specificity of 93.9% (considering healthy individuals and other infectious diseases patients). Only a minority of samples from Chagas disease patients possessed antibodies against rLb6H, and all of these responses were low (with a highest reactivity index of 2.2). Taken together, our data support further evaluation of rLb6H and the potential for its routine use in the serological diagnosis of ATL.
Early visual sensory deficits as endophenotypes for schizophrenia: high-density electrical mapping in clinically unaffected first-degree relatives.

CONTEXT The imperative to establish so-called endophenotypes-quantifiable measures of risk for neurological dysfunction-is a growing focus of research in schizophrenia. Electrophysiological markers of sensory processing, observable in human event-related potentials, hold great promise in this regard, lying closer to underlying physiology than descriptive clinical diagnostic tests. OBJECTIVE Early visual processing deficits, as measured by clear amplitude reductions in the occipital P1 component of the visual event-related potential, have been repeatedly demonstrated in patients with schizophrenia. However, before P1 amplitude may be considered as an endophenotypic marker for schizophrenia, it is necessary to establish its sensitivity to genetic liability. DESIGN, SETTING, AND PARTICIPANTS Event-related potential responses to simple visual isolated-check stimuli were examined in 25 clinically unaffected first-degree relatives of patients with schizophrenia and 15 DSM-IV-diagnosed schizophrenia probands and compared with responses from 26 healthy, age-matched control subjects. Using high-density electrical scalp recordings, between-groups analysis assessed the integrity of the visual P1 component across the 3 groups. The study was conducted at St Vincent's Psychiatric Hospital in Fairview, Dublin, Ireland. RESULTS Substantially reduced P1 amplitude was demonstrated in both relatives and probands compared with controls with topographical mapping and inverse source analysis localizing this deficit largely to midline regions in early visual sensory cortices and regions of the dorsal visual stream. Additional later differences between these groups, where the relatives actually show larger amplitude responses, may point toward compensatory mechanisms at play in relatives. CONCLUSIONS Our findings demonstrate a deficit in early visual processing in clinically unaffected first-degree relatives of patients with schizophrenia, providing evidence that this deficit may serve as a genetic marker for this disorder. The efficacy of using P1 amplitude as an endophenotype is underscored by the observation of a large effect size (d=0.9) over scalp sites where the deficit was maximal.
Nutrition status of children in Kasese district at the Uganda-Congo border.

OBJECTIVE To establish the magnitude and risk factors for malnutrition in Kasese district at the Uganda-Congo border. DESIGN Cross sectional nutrition survey. METHODS Thirty clusters were selected. The height, weight, and mid upper arm circumference of at least 31 children per cluster were measured. Data on food frequency, prevalence of cough, fever and diarrhoea was also collected. RESULTS Half of the 932 children (49.8%) were stunted, and 21.9% were severely stunted. While 17.4% of the children were under weight, 1.29% were wasted and 3.7% had MUAC <12.5 cm. Risk factors for stunting included not consuming milk, fathers' low formal education, having no immunisation card, and not breast feeding among 12-23 months old. Risk factors for underweight included fathers' and mothers' low education level, consumption of legumes, and fever or diarrhoea two weeks before the survey. For wasting the risk factors were consumption of vegetables, legumes or starchy foods. Those not consuming high-energy or animal foods including milk were likely to be severely wasted as were those not breast feeding in the 12-23 months age group. Fever or a diarrhoea episode two weeks preceding the survey and living in a female-headed household, were also risk factors for severe wasting. CONCLUSION Attention to education, poverty alleviation, appropriate feeding practices, prevention and treatment of infections might assist in combating malnutrition in this district.
Entrepreneurial urbanism, state restructuring and civilizing ‘New’ East Manchester

This paper draws on the ‘entrepreneurial turn’ literatures to examine the current redevelopment of East Manchester. It makes three contributions to our existing empirical and theoretical understanding of what is termed here ‘entrepreneurial urbanism’. First, attention is drawn to the spatially selective nature of entrepreneurial urbanism within cities; second, it argues that entrepreneurial urbanism actually demands a qualitative shift in the state's role in urban redevelopment and third, using the example of East Manchester, these two theoretical issues are explored empirically.
Transplacental Pharmacokinetics of Diclofenac in Perfused Human Placenta

The aims of this study were to evaluate the transplacental transfer properties of diclofenac and to determine the effect of l-lactic acid on the transplacental transfer of diclofenac. The maternal and fetal vessels of human placenta were perfused in a single-pass mode with a solution containing diclofenac and antipyrine. The transplacental pharmacokinetic model was fitted to the time profiles of the drug concentrations in the effluent and placenta to obtain transplacental pharmacokinetic parameters. In addition, chloride ion in the perfusate was partially replaced with l-lactic acid to see the change in the transplacental transfer properties of diclofenac. The TPTss value (ratio of the rate of amount transferred across the placenta to that infused in the steady state) of diclofenac was 2.22%, which was approximately one-third that of antipyrine and was significantly reduced in the presence of l-lactic acid. The transplacental pharmacokinetic model could adequately explain the transplacental transfer of diclofenac with influx clearances from maternal and fetal perfusates to placental tissue of 0.276 and 0.0345 ml/min/g cotyledon and efflux rate constants from placental tissue to maternal and fetal perfusates of 0.406 and 0.0337 min–1, respectively. By taking into account protein binding, the placental tissue/plasma concentration ratio in humans for diclofenac was estimated to be 0.108 ml/g of cotyledon and was smaller than that of antipyrine. In conclusion, human placental perfusion and transplacental pharmacokinetic modeling allowed us to determine the transplacental transfer properties of diclofenac quantitatively. Diclofenac may share transplacental transfer system(s) with l-lactic acid.
Globalization and French Cultural Identity

The nature of the French economy has changed radically in recent years. Breaking with its mercantilist and dirigiste past, France has since the early 1980s converted to market liberalization, both as the necessary by-product of European integration and globalization and as a deliberate effort by policymakers. Whereas the French state used to own large sectors of the economy, partly to keep them from foreign control, now even a Socialist-led government proceeds with privatization, with scant regard for the nationality of the buyer. French companies themselves have also been adapting to globalization, largely through a wave of international mergers and acquisitions over which the once all-powerful state has had little influence. France’s adaptation to the global world economy is finally paying off in terms of performance, which is now arguably better than it has been since the 1960s. It seems that for many in France, the loss of state control and growing inequalities that result from globalization may be a price worth paying for increased prosperity and jobs. Indeed, it is fair to say that where the economy is concerned, France has been quietly, steadily, and highly effectively adapting to globalization.1 Yet this is not the image that one usually associates with the French reaction to globalization. Instead of France’s remarkable adaptation, most observers have focused on France’s resistance to globalization—above all symbolized by the actions of the sheep farmer José Bové, who in August 1999 dismantled a McDonald’s restaurant to protest against US sanctions, the World Trade Organization (WTO), and globalization in general. France, of course, is hardly the only country worried about the consequences of globalization, and the street
Prayer, God Imagery, and Symptoms of Psychopathology

Researchers have shown a longstanding interest in the relationship between religion and mental health. Here, we outline a series of hypotheses linking personal prayer, images of God, and mental health. We then empirically test the hypotheses using data from an online survey of U.S. adults (N= 1,629) conducted in 2004 by Spirituality and Health magazine. We find a positive correlation between both frequency of prayer and the perception of God as remote and several different forms of psychopathology; a perceived intimate relationship with a loving God is inversely related. The positive association between prayer and psychopathology manifests itself primarily among individuals who experience God as either (a) remote or (b) not loving. We also find an inverse correlation between prayer and psychopathology among individuals who believe that they are praying to a close (the inverse of remote) God. We discuss the implications of these findings for research on the religion-mental health connection and outline an agenda for future research.
"Only God decides": young children's perceptions of divorce and the legal system.

OBJECTIVE To describe research on perceptions of children aged 6 and younger from 21 families of their parents' divorce, of its impact on their families, and of legal officials. METHOD Semistructured play interviews were conducted during home visits as parents were conjointly interviewed as part of a larger study on divorce in legal context. RESULTS Children had much mis-information about divorce as an event and process. What they did know was often inappropriate, frightening, and confusing. They resented how the process "ruined their parents' being friends any more" and proposed reforms based on their wishes and observations. CONCLUSIONS Greater awareness is needed of the child's desire to be heard during the process, to feel safe and less lonely, and to stay in touch with both parents and extended families. Age-appropriate explanations of psychological and legal aspects of the divorce process are likely to support children's positive adjustment and mental health.
Kawasaki Disease in Very Young Infants: High Prevalence of Atypical Presentation and Coronary Arteritis

K awasaki disease (KD) is an acute febrile vasculitis of early childhood and is the most common cause of acquired heart disease in the pediatric population. ' Since the etiology of KD is not known, the diagnosis is made by presentation of fever for at least 5 days and at least 4 of the following signs: bilateral nonpurulent conjunctivitis, polymorphous exanthema, erythema and swelling of palms and soles, inflammatory changes of lips and oral cavity, and cervical adenopathy.2 The most serious complication of KD is coronary arteritis, which has been observed in about 20% of the patients. ' Kawasaki disease is the most com-
Emergence of an Outbreak-Associated Clostridium difficile Variant with Increased Virulence

ABSTRACT The prevalence of Clostridium difficile infections has increased due to the emergence of epidemic variants from diverse genetic lineages. Here we describe the emergence of a novel variant during an outbreak in a Costa Rican hospital that was associated with severe clinical presentations. This C. difficile variant elicited higher white blood cell counts and caused disease in younger patients than did other strains isolated during the outbreak. Furthermore, it had a recurrence rate, a 30-day attributable disease rate, and disease severity as great as those of the epidemic strain NAP1. Pulsed-field gel electrophoresis genotyping indicated that the outbreak strains belong to a previously undescribed variant, designated NAPCR1. Whole-genome sequencing and ribotyping indicated that the NAPCR1 variant belongs to C. difficile ribotype 012 and sequence type 54, as does the reference strain 630. NAPCR1 strains are resistant to fluoroquinolones due to a mutation in gyrA, and they possess an 18-bp deletion in tcdC that is characteristic of the epidemic, evolutionarily distinct, C. difficile NAP1 variant. NAPCR1 genomes contain 10% more predicted genes than strain 630, most of which are of hypothetical function and are present on phages and other mobile genetic elements. The increased virulence of NAPCR1 was confirmed by mortality rates in the hamster model and strong inflammatory responses induced by bacteria-free supernatants in the murine ligated loop model. However, NAPCR1 strains do not synthesize toxin A and toxin B at levels comparable to those in NAP1 strains. Our results suggest that the pathogenic potential of this emerging C. difficile variant is due to the acquisition of hypothetical functions associated with laterally acquired DNA.
Extremes of eating are associated with reduced neural taste discrimination.

OBJECTIVE Eating disorders are severe psychiatric disorders of unknown etiology. Understanding how neuronal function affects food choices could help personalize treatment based on brain function. Here we wanted to determine whether disordered eating behavior is associated with alterations in the primary taste cortex's ability to classify taste stimuli, which could interfere with taste reward processing. METHOD One-hundred and six women, 27 healthy comparison (age 26.15 ± 6.95 years), 21 with restricting-type anorexia nervosa (AN; age 23.10 ± 6.14 years), 19 recovered from restricting-type AN (recovered AN; age 26.95 ± 5.31 years), 20 with bulimia nervosa (BN; age 25.15 ± 5.31 years), and 19 with obesity (age 28.16 ± 8.13 years), received sucrose, control solution or no taste stimulation during functional magnetic resonance brain imaging. Multivariate Bayesian pattern analysis (decoding) and cross-validation tested taste classification accuracy (adjusted for comorbidity, medication use, taste perception, interoception, and brain activation volume). RESULTS For sucrose versus control solution, classification accuracy differed (F = 2.53, P < 0.041). Post hoc tests indicated higher classification accuracy in healthy comparison compared to women with AN (P < 0.016) or obesity (P < 0.027), and in recovered AN as compared to AN (P < 0.016) or obesity (P < 0.047) groups. Taste stimulation resulted in sparse insula voxel activation across all groups. DISCUSSION Reduced classification accuracy across stimuli in women with AN or obesity could indicate low brain encoding discrimination of stimulus quality, which could contribute to altered reward activation and eating drive that is not adjusted to nutritional needs. This deficit appears to normalize with recovery from AN, but adjusting food flavor intensity could aid in the treatment of individuals with AN or obesity. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2016; 49:603-612).