Miracle-dz/UniFAR-FTUs huggingface dataset:
DREAM: Distributed RDF Engine with Adaptive Query Planner and Minimal Communication

The Resource Description Framework (RDF) and SPARQL query language are gaining wide popularity and acceptance. In this paper, we present DREAM, a distributed and adaptive RDF system. As opposed to existing RDF systems, DREAM avoids partitioning RDF datasets and partitions only SPARQL queries. By not partitioning datasets, DREAM offers a general paradigm for different types of pattern matching queries, and entirely averts intermediate data shuffling (only auxiliary data are shuffled). Besides, by partitioning queries, DREAM presents an adaptive scheme, which automatically runs queries on various numbers of machines depending on their complexities. Hence, in essence DREAM combines the advantages of the state-of-the-art centralized and distributed RDF systems, whereby data communication is avoided and cluster resources are aggregated. Likewise, it precludes their disadvantages, wherein system resources are limited and communication overhead is typically hindering. DREAM achieves all its goals via employing a novel graph-based, rule-oriented query planner and a new cost model. We implemented DREAM and conducted comprehensive experiments on a private cluster and on the Amazon EC2 platform. Results show that DREAM can significantly outperform three related popular RDF systems.
Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells

A 17.5-kDa trypsin inhibitor was purified from Phaseolus vulgaris cv. “gold bean” with an isolation protocol including ion exchange chromatography on DEAE-cellulose (Diethylaminoethyl-cellulose), affinity chromatography on Affi-gel blue gel, ion exchange chromatography on SP-sepharose (Sulfopropyl-sepharose), and gel filtration by FPLC (Fast protein liquid chromatography) on Superdex 75. It dose-dependently inhibited trypsin with an IC50 value of 0.4 μM, and this activity was reduced in the presence of dithiothreitol in a dose- and time-dependent manner, signifying the importance of the disulfide linkage to the activity. It inhibited [methyl-3H] thymidine incorporation by leukemia L1210 cells and lymphoma MBL2 cells with an IC50 value of 2.3 μM and 2.5 μM, respectively. The inhibitor had no effect on fungal growth and the activities of various viral enzymes when tested up to 100 μM.
Modeling fused filament fabrication machine height accuracy through layer thickness variation

This thesis addresses the modeling and prediction of total height error of a 3D printed part using a layer-by-layer approach. Layer to layer thickness error is modeled across the build height of Polyactic acid (PLA) and Acrylonitrile butadiene styrene (ABS) parts. A height error compensation model is then formulated and applied at a G-code level to drive the machine to print accurate parts. Preliminary experimentation was done on New Valance Robotics' two fused deposition modeling machine versions, the NVPro and the NVPro High-temp. Results suggested that the layer thickness approach was a viable technique for predicting total part height error. The compensation model for PLA parts was also tested and the compensated parts were significantly closer to the expected part height than the uncompensated prints. However, further experimentation will need to be carried out to solidify a model for ABS parts. Recommendations for future work, measurement method improvement, and model applications are also discussed. Thesis Supervisor: David E. Hardt Title: Ralph E. and Eloise F. Cross Professor of Mechanical Engineering
A High-Throughput Neural Network Accelerator

The authors designed an accelerator architecture for large-scale neural networks, with an emphasis on the impact of memory on accelerator design, performance, and energy. In this article, they present a concrete design at 65 nm that can perform 496 16-bit fixed-point operations in parallel every 1.02 ns, that is, 452 gop/s, in a 3.02mm2, 485-mw footprint (excluding main memory accesses).
Early gestation screening of pregnant women for iodine deficiency disorders and iron deficiency in urban centre in Vadodara, Gujarat, India

Pregnancy is a special condition where many metabolic changes may occur because of increased requirement of essential micronutrients such as iron and iodine. Foetal thyroid starts producing its own thyroid hormones after 12 weeks of gestation. Therefore, the first trimester is very crucial for meeting thyroid hormone requirements of the mother and foetus. Iodine deficiency and iron deficiency may affect mental and physical growth of the foetus. Hence, it is very important to establish a programme on the screening of pregnant women for thyroid dysfunction tests along with established iron status assessment. Thus, the study was aimed to screen the pregnant women for iodine deficiency disorders and iron deficiency during early gestation, situational analysis on thyroid insufficiency and iron deficiency in pregnant women (gestational age <15 weeks) in urban Vadodara, Gujarat. n = 256 healthy pregnant women with uncomplicated singleton pregnancy were selected. The thyroid hormone was estimated by RIA, UIE using simple microplate technique and haemoglobin (Hb) concentration by acid hematin method. Median thyrotropin (TSH), free thyroxine (FT4), total thyroxine (TT4) and UIE concentrations were 1.88 μIU/ml, 0.83 ng/dl, 10.24 μg/dl and 297.14 mcg/l, respectively. There was a significant correlation between TSH, FT4 and month of gestation. Mean Hb concentration was 9.27 ± 1.09 g/dl. The prevalence of iodine insufficiency (based on UI) was 16.79% and iron deficiency was 91%. Screening programme for iodine deficiency during early gestation should be implemented along with the existing programme of haemoglobin estimation at first prenatal visit. This would help prevent damage to the developing brain and growth of the foetus and also to trace at-risk pregnant women.
Examining the effect of user expectations on system use activity

It has been argued that the promising benefits of Enterprise Systems (ES) implementations are overshadowed by their high failure rate. One of the commonly cited reasons for ES implementation failures is the end-user’s unwillingness to adopt or use systems. Considering that the appropriate management of expectations may play an important role in forming positive behavior toward newly implemented systems, this study examines the effect of outcome expectations on the system use activity in the mandatory-use context of information systems (IS) from the perspectives of Social Cognitive Theory and Coping Theory. Structural equation model analysis using LISREL 8.7 provides significant support for the proposed relationships. The empirical results suggest that outcome expectations and user satisfaction have positive effects on system use activity conceptualized by immersion, reinvention, and learning. Theoretical and practical implications of the study shed some light on how to improve system use activity in the mandatory-use context of IS.
Potential use of fly ash and bagasse ash as secondary abrasives in phenolic composites for eco-friendly brake pads applications

Brake pad is the essential component of disk brake in automotive applications that is made of phenolic-based composites. The alumina and silica are often used as primary abrasives in brake pads. In this study, we investigated the hardness, compressive, friction and wear properties under room temperature and elevated temperatures (100°C and 150°C) of phenolic-based composites containing the natural ashes of fly ash and bagasse ash as secondary abrasives, which ranged from 0 to 12 wt%, for replacing primary abrasives. The results suggested that 4 wt% secondary abrasives was recommended for optimization of the overall properties of the composites. It was found that all composites exhibited the abrasive wear behavior evidenced by wear debris between the counterfaces acting as third-body abrasives. The phenolic-based composites at 100°C and 150°C had higher coefficient of friction and lower wear resistance than those at room temperature. The incorporation of bagasse ash resulted in more compression for a given load than that of fly ash. In summary, the fly ash and bagasse ash, which were natural ashes, showed a potential use as secondary abrasives in the phenolic-based composites for eco-friendly brake pads.
Cytomegalovirus myocarditis.

-Infection with human cytomegalovirus is common and world wide. In this country about 55 per cent of the population show evidence of past infection by the age of 35, and thereafter primary infection is rare (Stem, 1968). This virus is rarely recognized as a cause of overt disease, and it is difficult to , prove cause and effect when the infection is associated with another common condition. Furthermore, the virus may lie dormant in the cells of the host until relit by a concurrent debilitating illness. Therefore a rise in cytomegalovirus titre may indicate a primary infection, or reactivation of latent virus by an , unassociated illness. Congenital cytomegalovirus infection may cause cytomegalic inclusion disease, microcephaly, and mental deficiency (Lamb, I97I), and acquired infection may lead to pneumonia (Carlstrom et al., I968), hepatocellular jaundice (Lamb and Stem, I966), hepatitis (Toghill et al., I967), pericarditis (Rasanen and Saikku, I967), aseptic meningitis and polyneuritis (Klemola et al., i967a), acute haemolytic anaemia (Coombs, I968), cytomegalovirus mononucleosis (Klemola and Kaariainen, I965), postperfusion syndrome (Kaariiinen, Klemola, and Paloheimo, I966), and a disseminated infection in nimunosuppressed and debilitated patients (Rifkind, Goodman, and Hill, I967). In the following case we suggest that cytomegalovirus infection was the cause of myocarditis.
Characterization of human T- and B-cell epitopes in the C terminus of Plasmodium falciparum merozoite surface protein 1: evidence for poor T-cell recognition of polypeptides with numerous disulfide bonds

We have investigated the relationship between cellular and humoral immune responses to defined epitopes of the C terminus of merozoite surface protein 1 (MSP-1) of the human malaria parasite, Plasmodium falciparum, in immune blood donors. Sera from almost all donors contained antibodies to the 33-kDa processing product of the MAD20 allele of MSP-1 (MSP-1(33)), but these antibodies did not cross-react with the equivalent sequence of the Wellcome allele. In contrast, T-cell responses to MSP-1(33) are directed towards epitopes that are conserved between the two allelic families. Only 50% of adult blood donors possessed antibodies which recognized the 19-kDa processing product of MSP-1 (MSP-1(19)). These antibodies predominantly recognized conserved epitopes involving both of the constituent epidermal growth factor-like domains of MSP-1(19). T-cell responses were found in only 26% (for recombinant proteins) or 44% (for synthetic peptides) of donors and were directed mainly at dimorphic sequences of the protein. There was no obvious association, at an individual level, between the presence of antibodies and the detection of T-cell proliferative or gamma interferon responses, suggesting that the T cells identified in this manner are not providing significant levels of help to B cells. T-cell responses to reduced recombinant proteins and linear peptides were more prevalent than responses to disulfide-bonded proteins, suggesting that the complex disulfide-bonded structure of native MSP-1(19) may inhibit antigen processing or presentation.
Use of combined molecular biomarkers for prediction of clinical outcomes in locally advanced tonsillar cancers treated with chemoradiotherapy alone

Environmental exposures to tobacco, alcohol, human papillomavirus (HPV) and/or Epstein‐Barr virus (EBV), all of which can perturb multiple cell cycle proteins or tumor suppressors, have been implicated in the pathogenesis of different subsets of head and neck cancers. The aim of this study was to investigate to which extent the virus infection by itself, and/or the altered cell cycle proteins, contributes to prognosis in locally advanced tonsillar squamous cell carcinomas (TSCCs) treated with concurrent chemoradiotherapy (CCRT) alone.
Low-dose aspirin as treatment for central serous chorioretinopathy

Purpose: To evaluate the effectiveness of low-dose aspirin for the treatment of central serous chorioretinopathy (CSCR). Patients and methods: Patients with classical or multifocal CSCR were treated with aspirin 100 mg per day orally for 1 month followed by 100 mg on alternate days for 5 months. Treated patients were compared with historic controls consisting of patients with classical or multifocal CSCR previously followed up at our institution. Results: Mean visual acuity in the group treated with aspirin started to improve after the first week of therapy and continued to improve throughout the following 3 months. Visual recovery was slower in the untreated control group than in the treated group and achieved better visual acuity between the first and third month from the onset of the disease. There were no adverse events related to the administration of aspirin. Conclusion: The results indicate that treatment with low-dose aspirin may result in more rapid visual rehabilitation with fewer recurrences in patient with CSCR compared with untreated historic controls. The effectiveness of treatment with aspirin supports our hypothesis regarding the role of impaired fibrinolysis and increased platelet aggregation in the choriocapillaris in the pathogenesis of CSCR.
Reconstructing the Origin of Helianthus deserticola: Survival and Selection on the Desert Floor

The diploid hybrid species Helianthus deserticola inhabits the desert floor, an extreme environment relative to its parental species Helianthus annuus and Helianthus petiolaris. Adaptation to the desert floor may have occurred via selection acting on transgressive, or extreme, traits in early hybrids between the parental species. We explored this possibility through a field experiment in the hybrid species’ native habitat using H. deserticola, H. annuus, H. petiolaris, and two populations of early‐generation (BC2) hybrids between the parental species, which served as proxies for the ancestral genotype of the ancient hybrid species. Character expression was evaluated for each genotypic class. Helianthus deserticola was negatively transgressive for stem diameter, leaf area, and flowering date, and the latter two traits are likely to be advantageous in a desert environment. The BC2 hybrids contained a range of variation that overlapped these transgressive trait means, and an analysis of phenotypic selection revealed that some of the selective pressures on leaf size and flowering date, but not stem diameter, would move the BC2 population toward the H. deserticola phenotype. Thus, H. deserticola may have originated from habitat‐mediated directional selection acting on hybrids between H. annuus and H. petiolaris in a desert environment.
The Kinematics of a Globally Propagating Disturbance in the Solar Corona

The kinematics of a globally propagating disturbance (also known as an “EIT wave”) is discussed using Extreme UltraViolet Imager (EUVI) data from the Solar Terrestrial Relations Observatory (STEREO). We show for the first time that an impulsively generated propagating disturbance has similar kinematics in all four EUVI passbands (304, 171, 195, and 284 Å). In the 304 Å passband the disturbance shows a velocity peak of 238 ± 20 km s−1 within ~28 minutes of its launch, varying in acceleration from 76 to –102 m s−2. This passband contains a strong contribution from a Si XI line (303.32 Å) with a peak formation temperature of ~1.6 MK. The 304 Å emission may therefore be coronal rather than chromospheric in origin. Comparable velocities and accelerations are found in the coronal 195 Å passband, while lower values are found in the lower cadence 284 Å passband. In the higher cadence 171 Å passband the velocity varies significantly, peaking at 475 ± 47 km s−1 within ~20 minutes of launch, with a variation in acceleration from 816 to –413 m s−2. The high image cadence of the 171 Å passband (2.5 minutes compared to 10 minutes for the similar temperature response 195 Å passband) is found to have a major effect on the measured velocity and acceleration of the pulse, which increase by factors of ~2 and ~10, respectively. This implies that previously measured values (e.g., using EIT) may have been underestimated. We also note that the disturbance shows strong reflection from a coronal hole in both the 171 and 195 Å passbands. The observations are consistent with an impulsively generated fast-mode magnetoacoustic wave.
Recent advances in the diagnosis and treatment of childhood tuberculosis

Despite over 2.3 million (26% of global burden) cases of tuberculosis (TB) in India the accurate diagnosis of childhood TB remains a major challenge. Children with TB usually have paucibacillary disease and contribute little to disease transmission within the community. Consequently the treatment of children with TB is often not considered a priority by TB control programmes. Adequate and timely assessment of TB infection in childhood could diminish epidemiological burden as underdiagnosed pediatric patients can eventually evolve in to an active state and have the potential to disseminate the etiological agent Mycobacterium tuberculosis, notably increasing this worldwide public health problem. In this review we discuss the most important recent advances in the diagnosis of childhood TB: (1) Symptom-based approaches, (2) novel immune-based approaches, including in vitro interferon-γ IGRA release assays IGRA tests; and (3) bacteriological and molecular methods that are more rapid and/or less expensive than conventional culture techniques for TB diagnosis and/or drug-resistance testing. Recent advances have improved our ability to diagnose latent infection and active TB in children, nevertheless establishing a diagnosis of either latent infection or active disease in HIV-infected children remains a major challenge.
Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells.

BACKGROUND The use of suitable cells transplanted into periodontal osseous defects appears to be a powerful strategy to promote periodontal tissue regeneration. Mesenchymal stem cells (MSCs) isolated from bone marrow have the potential for multilineage differentiation. The purpose of this study was to examine whether auto-transplantation of MSCs into periodontal osseous defects would be useful for periodontal tissue regeneration. METHODS Bone marrow MSCs were isolated from beagle dogs and expanded in vitro. The expanded MSCs were mixed with atelocollagen (2% type I collagen) at final concentrations of 2 x 10(6), 5 x 10(6), 1 x 10(7), or 2 x 10(7) cells/ml, and auto-transplanted into experimental Class III defects. Atelocollagen alone was implanted into the defects as a control. Periodontal tissue healing was evaluated by histological and morphometric analyses 1 month after transplantation. RESULTS The defects were regenerated with cementum, periodontal ligament, and alveolar bone in the MSC-atelocollagen groups. Less periodontal tissue regeneration was observed in the control group compared to the MSC-atelocollagen groups. Morphometric analysis revealed that the percentage of new cementum length in the 5 x 10(6) and 2 x 10(7) cells/ml groups and the percentage of new bone area in the 2 x 10(7) cells/ml group were significantly higher than in the control group (P < 0.01). CONCLUSION These findings suggest that auto-transplantation of bone marrow mesenchymal stem cells is a novel option for periodontal tissue regeneration.
Designing and testing visual representations of draft essays for higher education students

This paper reports the findings of an empirical investigation, which set out to test a set of rainbow essay exercises. The rainbow diagrams are pictorial representations of formal graphs that are derived automatically from student essays. They were designed to allow students to discover how key concepts in a well written essay are connected together. The students would then be able to compare a rainbow diagram of their own essay with a good essay and make changes to it before submission to their tutor. However a trail was undertaken with academics, teaching and learning staff, doctoral students at the Open University of Catalonia and the Open University UK, before implementation into the web application known as Open Essayist. All the participants from each University completed the exercise correctly. This was a surprising finding as we expected participants to experience some difficulties, as previous visual representations we piloted. All the participants remarked that they had learnt a lot about the structure of good essays and more importantly how clear the role of the conclusion played in a well-constructed essay. This type of representation made this explicit and they would be able to see quickly if a second draft had improved. The users also mentioned that the rainbow diagram representations could be used as a generic essay feedback tool. It could be used across subject domains, a hypothesis worthy of further investigation.
Attitudes to safety culture among professional divers and offshore workers. HSE Report RR159

This report investigates the importance professional divers and offshore workers give to safety culture in reducing accident probability. Using a conjoint analysis method 'accident risk' scenarios were used to estimate weights for influence of safety culture, quality of workplace supervision, time pressure and worker competency. The 'expected' weighting, if all factors were equally significant was 1.0 for each factor. All four factors contributed significantly to participants' assessment of accident probability but highest weighting was given to quality of supervision (1.48). Safety culture was given significantly lower weighting by offshore divers (0.74) than offshore workers (0.97). Time/financial pressure and worker competency were given close to expected weightings. Weightings were not influenced by supervisory status, accident history or being in current offshore industry employment. Participants were also asked to define safety culture in their own words. Definitions of safety culture were associated with the role of the organisation/company, the role of management, individual safety awareness, equipment and team/group interaction. This report and the work it describes were funded by the Health and Safety Executive (HSE). Its contents, including any opinions and/or conclusions expressed, are those of the authors alone and do not necessarily reflect HSE policy. ISBN 0 7176 2763 2 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means (electronic, mechanical, photocopying, recording or otherwise) without the prior written permission of the copyright owner. ii SUMMARY The aim of this two-year study was to investigate worker attitudes to safety culture as one of the factors in controlling accident risk within the UK Continental Shelf Oil and Gas Industry. 233 professional divers (70% of whom had worked in the Oil and Gas Industry) and 120 non-diving age matched offshore workers (all of whom had worked in the Oil and Gas Industry) were surveyed. All participants were taking part in the Examination of the Long Term Health Impact of Diving (the ELTHI Diving Study) at University of Aberdeen in 2001/2002. These participants had been selected on the basis of either having a valid fitness to work offshore certificate in 1990-2, or a diving certificate before 1991. This means that those taking part, who were working in the offshore industry, were doing so around the time of a significant change in safety management in the wake of the Piper Alpha disaster. A preliminary 'expert discussion' identified three attributes …