Miracle-dz/UniFAR-FTUs huggingface dataset:
Mixed Convection Heat and Mass Transfer with Phase Change and Flow Reversal in Channels

Due to its widespread applications, heat and mass transfer in an air stream with liquid film evaporation or condensation in open channels has received considerable attention in the literature. This kind of flows is present in many natural and engineering processes, such as human transpiration, desalination, film cooling, liquid film evaporator, cooling of microelectronic equipments and air conditioning. Since the original theory for flow of a mixture of vapour and a non-condensable gas by Nusselt (1916) and its extension by Minkowycz & Sparrow (1966), many theoretical and experimental studies have been published in the literature. These studies deal with different geometric configurations such as a flat plate, parallel-plate channel and rectangular or circular-section ducts. Heat and mass transfer convection over a flat plate wetted by a liquid film has been investigated by Vachon (1979). He performed an analytical and experimental study of the evaporation of a liquid film streaming along a porous flat plate into a naturally driven airflow. This author established correlations for Nusselt and Sherwood numbers in connection with a combined Grashof number. Ben Nasrallah & Arnaud (1985) investigated theoretically film evaporation in buoyancy driven airflow over a vertical plate heated with a variable heat flux. The solutions of the governing equation have been obtained by means of semi-analytical and finite difference methods. The authors present their results in term of expressions of the wall temperature and mass fraction as well as the local Nusselt and Sherwood numbers. A numerical and experimental analysis has been carried out by Tsay et al. (1990) to explore the detailed heat transfer characteristics for a falling liquid film along a vertical insulated flat plate. Free stream air temperature was set at 30°C and inlet liquid film temperature was taken equal to 30°C or 35°C. The results show that latent heat transfer connected with vaporization is the main cause for cooling of the liquid film. The authors affirm that when the inlet liquid temperature is equal to the ambient one, latent heat transfer due to the film vaporization initiates heat transfer in the film and gas flow. Aguanoun et al (1994; 1998) studied numerically the evaporation of a falling film on an inclined plate heated
The shorter the better? A follow-up analysis of 10-session psychiatric treatment including the motive-oriented therapeutic relationship for borderline personality disorder

Abstract Objective: There is little research on short-term treatments for borderline personality disorder (BPD). While the core changes may occur only in long-term treatments, short-term treatments may enable the study of early generic processes of engagement in therapy and thus inform about effective treatment components. It was shown that a 10-session version of a psychiatric treatment was effective in reducing borderline symptoms at the end of this treatment [Kramer, U. , Kolly, S. , Berthoud, L. , Keller, S. , Preisig, M. , Caspar, F. , … Despland, J.-N. (2014). Effects of motive-oriented therapeutic relationship in a ten-session general psychiatric treatment for borderline personality disorder: A randomized controlled trial. Psychotherapy and Psychosomatics, 83, 176–186. ]. Also, it was demonstrated in a randomized design that adding the motive-oriented therapeutic relationship (MOTR), following an individualized case formulation based on Plan Analysis, further increased general outcome after session 10 and had a positive effect on the early changes in self-esteem and alliance. Method: The present study focuses on the follow-up period after this initial treatment, examining treatment density and outcomes after 6 months and service utilization after 12 months. Outcome was measured using the OQ-45. Results: Results on a sub-sample of N = 40 patients with available OQ-45 data at follow-up (n = 21 for MOTR-treatment, n = 19 for comparison treatment) showed maintenance of gains over the follow-up period, which did not differ between both conditions. It appeared for this sample that MOTR treatments, while using the same number of sessions, lasted more weeks (i.e., lower treatment density, defined as the number of sessions per week), when compared to the treatments without MOTR. Density marginally predicted symptom reduction at follow-up. Patients in MOTR treatments had a greater likelihood of entering structured psychotherapy after the initial sessions than patients in the comparison group. Conclusions: These results are overall consistent with earlier studies on short-term treatments for BPD and underline the importance of individualizing interventions, by using case formulations that rely on idiographic methods and integrative concepts.
Short Sleep Duration Among Middle School and High School Students — United States, 2015

Insufficient sleep among children and adolescents is associated with increased risk for obesity, diabetes, injuries, poor mental health, attention and behavior problems, and poor academic performance (1-4). The American Academy of Sleep Medicine has recommended that, for optimal health, children aged 6-12 years should regularly sleep 9-12 hours per 24 hours and teens aged 13-18 years should sleep 8-10 hours per 24 hours (1). CDC analyzed data from the 2015 national, state, and large urban school district Youth Risk Behavior Surveys (YRBSs) to determine the prevalence of short sleep duration (<9 hours for children aged 6-12 years and <8 hours for teens aged 13-18 years) on school nights among middle school and high school students in the United States. In nine states that conducted the middle school YRBS and included a question about sleep duration in their questionnaire, the prevalence of short sleep duration among middle school students was 57.8%, with state-level estimates ranging from 50.2% (New Mexico) to 64.7% (Kentucky). The prevalence of short sleep duration among high school students in the national YRBS was 72.7%. State-level estimates of short sleep duration for the 30 states that conducted the high school YRBS and included a question about sleep duration in their questionnaire ranged from 61.8% (South Dakota) to 82.5% (West Virginia). The large percentage of middle school and high school students who do not get enough sleep on school nights suggests a need for promoting sleep health in schools and at home and delaying school start times to permit students adequate time for sleep.
Thermally Responsive Hydrogel-Nanoparticle Composite Materials for Therapeutic Delivery

Thermally Responsive Hydrogel-Nanoparticle Composite Materials for Therapeutic Delivery by Laura Elizabeth Strong Department of Biomedical Engineering Duke University Date:_______________________ Approved: ___________________________ Jennifer L. West, Supervisor ___________________________ Ashutosh Chilkoti ___________________________ Farshid Guilak ___________________________ Nimmi Ramanujam ___________________________ William M. Reichert An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, in the Department of Biomedical Engineering in the Graduate School of Duke University 2014 Copyright by Laura Elizabeth Strong 2014
Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum

Gametocyte maturation in Plasmodium falciparum is a critical step in the transmission of malaria. While the majority of parasites proliferate asexually in red blood cells, a small fraction of parasites undergo sexual conversion and mature over 2 weeks to become competent for transmission to a mosquito vector. Immature gametocytes sequester in deep tissues while mature stages must be able to circulate, pass the spleen and present themselves to the mosquito vector in order to complete transmission. Sequestration of asexual red blood cell stage parasites has been investigated in great detail. These studies have demonstrated that induction of cytoadherence properties through specific receptor–ligand interactions coincides with a significant increase in host cell stiffness. In contrast, the adherence and biophysical properties of gametocyte‐infected red blood cells have not been studied systematically. Utilizing a transgenic line for 3D live imaging, in vitro capillary assays and 3D finite element whole cell modelling, we studied the role of cellular deformability in determining the circulatory characteristics of gametocytes. Our analysis shows that the red blood cell deformability of immature gametocytes displays an overall decrease followed by rapid restoration in mature gametocytes. Intriguingly, simulations suggest that along with deformability variations, the morphological changes of the parasite may play an important role in tissue distribution in vivo. Taken together, we present a model, which suggests that mature but not immature gametocytes circulate in the peripheral blood for uptake in the mosquito blood meal and transmission to another human host thus ensuring long‐term survival of the parasite.
PSLO: enforcing the Xth percentile latency and throughput SLOs for consolidated VM storage

It is desirable but challenging to simultaneously support latency SLO at a pre-defined percentile, i.e., the Xth percentile latency SLO, and throughput SLO for consolidated VM storage. Ensuring the Xth percentile latency contributes to accurately differentiating service levels in the metric of the application-level latency SLO compliance, especially for the application built on multiple VMs. However, the Xth percentile latency SLO and throughput SLO enforcement are the opposite sides of the same coin due to the conflicting requirements for the level of IO concurrency. To address this challenge, this paper proposes PSLO, a framework supporting the Xth percentile latency and throughput SLOs under consolidated VM environment by precisely coordinating the level of IO concurrency and arrival rate for each VM issue queue. It is noted that PSLO can take full advantage of the available IO capacity allowed by SLO constraints to improve throughput or reduce latency with the best effort. We design and implement a PSLO prototype in the real VM consolidation environment created by Xen. Our extensive trace-driven prototype evaluation shows that our system is able to optimize the Xth percentile latency and throughput for consolidated VMs under SLO constraints.
Construction loads using a shoring–clearing–striking process

This paper presents the results of tests carried out during the construction of a block of flats with reinforced concrete slab floors in Madrid, Spain, using the shoring, clearing and striking process. Loads on shores were recorded during the different construction stages of floor slabs 1 to 6. The experimental results were used to analyse load transmission between slabs and shores during the construction of the building. The results of the analysis showed that slab–shore load transmission differed according to the position of the span analysed, and also that variations in the construction process had a significant effect on the expected loads. The paper includes the evolving calculation developed using a non-linear numerical model to simulate the building's behaviour during the different construction phases and variations in concrete properties with time. Experimental and numerical finite-element model results are compared with those obtained by applying simplified methods that consider the real stiffnes.
Phytochemical Composition and Biological Activities of Dyssodia tagetiflora Lag.

While plants of the genus Dyssodia are used by man to a certain extent, few phytochemical and pharmacological studies have been performed with species of this genus. D. tagetiflora is an endemic plant of Mexico and has been used as fodder. The aim of this research was to isolate and identify the main bioactive components and evaluate the insecticidal, antioxidant, genotoxic and cytoprotective activities of D. tagetiflora. The isolated substances included an essential oil composed of six monoterpenes, and extracts containing two flavonols, three flavonol‐glycosides and four thiophenes. The compounds were characterized using spectroscopic and spectrometric methods, including GC/MS, MS and NMR. The essential oil showed insecticidal activity against Drosophila melanogaster larvae. The methanolic extract of D. tagetiflora (DTME) had strong antioxidant activity against DPPH and ABTS radicals; DTME showed no evidence of genotoxic or cytotoxic effects. In contrast, DTME showed a cytoprotective effect attenuating the formation of H2O2‐induced micronuclei in Vicia faba roots. This report is the first to describe the phytochemical and biological activity of D. tagetiflora.
A clinical risk score to identify patients at high risk of very late stent thrombosis

OBJECTIVES The aim of this study was to determine predictors of very late stent thrombosis (VLST; >1 year after stenting), and to evaluate whether addition of these predictors to the dual antiplatelet therapy (DAPT) score would improve the ability to identify patients at high risk of VLST who might benefit from DAPT. BACKGROUND VLST is a severe complication of percutaneous coronary intervention (PCI). Extended knowledge about the predictors of VLST is needed to prevent this life-threatening complication. Recent data showed a reduction in VLST after treatment with prolonged DAPT. The DAPT study developed a prediction score to identify patients after PCI who might benefit from prolonged DAPT duration. METHODS The Dutch stent thrombosis study is a multi-center case-control study. Consecutive patients with definite VLST were included between 2007 and 2014. Baseline characteristics from the index PCI were collected. Independent predictors of VLST were identified and added to the DAPT score to develop the VLST score. RESULTS In total, 155 VLST cases and 155 matched controls were included. Suboptimal result of stenting, right coronary artery as target vessel, and diffuse coronary artery ectasia were independent predictors of VLST, and added to the DAPT score. The power of the VLST score to identify patients who experienced VLST was increased (AUC, 95%CI; DAPT score: 0.64, 0.57-0.70; VLST score: 0.70, 0.63-0.76, P = 0.010). CONCLUSIONS Addition of newly identified independent predictors of VLST resulted in a prediction model with a higher ability to identify patients at high risk of VLST who might benefit from prolonged DAPT.
Tool Wear in Turning of Graphitic Hybrid Metal Matrix Composites

This study presents an experimental investigation on tool wear in machining Al 2219/15SiCp and Al 2219/15SiCp-3Gr (hybrid) composites at different cutting conditions with carbide, coated carbide, and polycrystalline diamond (PCD) tools. An attempt is made in the present investigation to study the effect of graphite incorporation in Al 2219/15SiCp composite on tool wear. The results reveal that the incorporation of graphite in Al 2219/15SiCp composite reduces tool wear at all cutting conditions. This is due to graphite, which reduces the coefficient of friction between tool and workpiece and between tool and chip interface. PCD tool performs better than carbide and coated carbide tools.
Breast Cancer Cell Line Aggregate Morphology Does Not Predict Invasive Capacity

To invade and metastasize to distant loci, breast cancer cells must breach the layer of basement membrane surrounding the tumor and then invade through the dense collagen I-rich extracellular environment of breast tissue. Previous studies have shown that breast cancer cell aggregate morphology in basement membrane extract correlated with cell invasive capacity in some contexts. Moreover, cell lines from the same aggregate morphological class exhibited similarities in gene expression patterns. To further assess the capacity of cell and aggregate morphology to predict invasive capacity in physiologically relevant environments, six cell lines with varied cell aggregate morphologies were assessed in a variety of assays including a 3D multicellular invasion assay that recapitulates cell-cell and cell-environment contacts as they exist in vivo in the context of the primary breast tumor. Migratory and invasive capacities as measured through a 2D gap assay and a 3D spheroid invasion assay reveal that breast cancer cell aggregate morphology alone is insufficient to predict migratory speed in 2D or invasive capacity in 3D. Correlations between the 3D spheroid invasion assay and gene expression profiles suggest this assay as an inexpensive functional method to predict breast cancer invasive capacity.
Polymer Optical Fiber for In-Shoe Monitoring of Ground Reaction Forces During the Gait

Ground reaction force (GRF) measurement is usually made by means of force platforms, which can lead to errors when the foot is not precisely placed inside the platform boundaries. Although electronic in-shoe plantar pressure sensors solve this problem, they lack in stability, robustness to impact loads and also can present some errors and inconsistencies. Polymer optical fibers (POF) present high elastic strain limits, fracture toughness, flexibility in bend, and relative low cost and are not influenced by electromagnetic fields, which enable their application for in-shoe plantar pressure measurements. This paper presents an in-shoe system to measure the vertical GRF during the gait cycle. The system comprises of four POF sensors in an insole. Since the polymer does not have a constant response with stress or strain due to its viscoelasticity, a compensation technique for this effect is also proposed. The proposed insole is compared with a commercial force platform, and a root mean squared error of 5.30 N was obtained. Results also show the feasibility of the system to measure the GRF during the gait and the identification of all subdivisions of the stance phase with the additional advantages of full portability, lower cost, and higher flexibility than the one presented by commercial force platforms and fiber Bragg gratings-based insoles.
Dietary outcomes of overweight fathers and their children in the Healthy Dads, Healthy Kids community randomised controlled trial

BACKGROUND Few studies have examined dietary intake changes following a weight loss intervention in fathers and the association between father-child dietary intakes. The present study aimed to: (i) evaluate the change in dietary intake in overweight fathers randomised to a family-based lifestyle intervention [Healthy Dads Healthy Kids (HDHK)] versus controls and (ii) investigate whether an association exists between father-child dietary intakes. METHODS A secondary analysis was conducted of father-child baseline and 3-month post-intervention data (n = 93) collected in the HDHK community randomised controlled trial. Intention-to-treat linear mixed models were used to assess dietary changes by group, time (baseline and 3-month) and the group-by-time interaction. Cohens d was used to determine effect sizes. RESULTS Significant group-by-time effects (all P < 0.05) favouring fathers in the intervention group were identified for total daily energy intake (-1956 kJ, d = 0.74), total sugars (-45 g, d = 0.63), sodium (-414 mg, d = 0.58) and % energy from nutrient-dense, core foods (+10.1%, d = 0.86), fruit (+2.4%, d = 0.71), vegetarian protein sources (+1.2%, d = 0.57), pre-packed snacks (+1.7%, d = 0.58) and sugar-sweetened beverages (-4.1%, d = 0.58). At baseline, positive correlations were observed between father-child intakes for a number of dietary variables, and significant correlations were observed between father-child change scores for % energy carbohydrate (r = 0.35, P = 0.023), % energy from fruit (r = 0.47, P = 0.002), vegetarian protein sources (r = 0.46, P = 0.002) and frequency of consuming meals with vegetables (r = 0.38, P = 0.012). CONCLUSIONS The HDHK intervention successfully improved some aspects of father's dietary intakes compared to controls. The fathers' eating patterns also correlated with those of their children for several dietary variables. These novel data suggest that fathers can be targeted as agents of dietary change within obesity prevention and treatment programmes.
Medications and Patient Characteristics Associated With Falling in the Hospital

Objectives The aim of this study was to evaluate specific medications and patient characteristics as risk factors of falling in the hospital. Methods This is a case-control study comparing demographic, health, mobility, and medication data for 228 patients who fell between June 29, 2007, and November 14, 2007, at a large tertiary care hospital and 690 randomly selected control patients. Logistic regression was used to identify fall risk factors. Results Independent risk factors of falling included history of falls (odds ratio [OR], 2.7; 95% confidence interval [CI], 1.8–4.2); needing an assistive device (OR, 3.2; 95% CI, 1.5–6.8) or person assistance (OR, 2.1; 95% CI, 1.3–3.3) to ambulate; being underweight (OR, 2.4; 95% CI, 1.2–4.7) or obese (OR, 1.6; 95% CI, 1.0–2.5); confusion (OR, 2.4; 95% CI, 1.5–4.0); dizziness (OR, 2.1; 95% CI, 1.1–4.3); incontinence (OR, 1.5; 95% CI, 1.0–2.3); and an order for a hydantoin (OR, 3.3; 95% CI, 1.3–8.0) or benzodiazepine anticonvulsant (OR, 2.2; 95% CI, 1.5–3.3), haloperidol (OR, 2.8; 95% CI, 1.2–6.8), tricyclic antidepressant (OR, 2.4; 95% CI, 1.2–4.9), or insulin (OR, 1.5; 95% CI, 1.0–2.1). Female sex (OR, 0.8; 95% CI, 0.6–1.0), proton pump inhibitors (OR, 0.6; 95% CI, 0.4–0.9), and muscle relaxants (OR, 0.4; 95% CI, 0.3–0.7) were associated with lower risk for falling. Conclusions This study identified medications and patient characteristics associated with increased risk for falling in the hospital. High-risk medications identified in this study may serve as targets for medication review or adjustment, which have been recommended as a component of multifaceted fall prevention programs.
PIMCH: Cooperative memory prefetching in processing-in-memory architecture

Conventional high-performance processors employ hardware data prefetcher to reduce the cache miss rate by exploiting data locality in memory access. In the scenario of PIM-enabled system, current prefetching methods are likely to induce unnecessary data moving between memory and CPU, resulting in significant performance slow-down if ignoring the data access pattern of the In-Memory cores of PIM architecture. In this paper, we propose a novel PIM-oriented Prefetching (PIMCH), to fix this problem for the heterogeneous system with both conventional CPU cores and PIM architectures. PIMCH consider the memory behavior of both CPU cores and PIM cores, and refers to their data mapping to dynamically adjust prefetching methods, which enables cooperative memory prefetching in Processing-InMemory architecture.