Miracle-dz/UniFAR-FTUs huggingface dataset:
Tough doughnuts: affect and the modulation of attention

Positive affect has been associated with improvement in performance in various attentional domains. Negative affect has been associated with narrowing of attention and lowering of performance in attentional tasks. Previous behavioral studies have put forth the diffuse mental state idea as the mechanism of these effects, where attentional resources are more evenly distributed during positive affect and more focused during negative affect. To explore neural correlates of this mechanism, a two-stream rapid serial visual presentation (RSVP) paradigm with centrally presented, overlapping streams was used. Participants attended one of the streams at a time and steady-state visual evoked potentials (ssVEP) in response to the attended and unattended streams were recorded in a positive, negative or neutral affect state. We predicted that in the positive affect condition, ssVEP responses to the attended and the unattended stream would be more alike than in a neutral condition. In the negative affect condition, as an expression of a less diffuse mental state, ssVEP responses were predicted to be more dissimilar. Self-assessments confirmed the effectiveness of the emotional manipulation. In the negative affect condition power was found to be higher than in the neutral condition. However, the modulations in the ssVEP did not reflect the predicted neural correlate of the diffuse mental state mechanism. Thus, the results provide evidence for negative affect modulating attention but suggest that the diffuse mental state is not a spatially oriented phenomenon.
When semantics means less than morphology: The processing of German prefixed verbs

This study investigated whether form and meaning relatedness modulate the processing of morphologically related German verbs. In two overt visual priming experiments, we compared responses for verb targets (kommen, come) that were preceded by a purely semantically related verb (nahen, approach), by a morphologically and semantically related verb (mitkommen, come along), by a purely morphologically related verb (umkommen, perish), or by an unrelated verb (schaden, harm). In Experiment 1, morphological relatedness produced robust facilitation, which was not influenced by semantic relatedness. Moreover, this morphological facilitation was far stronger than the priming by purely semantically related verbs. In Experiment 2, orthographically similar primes (kämmen, comb) produced interference effects and thus indicated that the morphological facilitation effects were not the result of sheer form overlap between primes and targets. These findings argue for a single system that processes morphological relations independently of form and meaning relatedness.
Young, Massive Star Candidates Detected throughout the Nuclear Star Cluster of the Milky Way

Aims. Young, massive stars have been found at projected distances R 0.5 pc. Our goal in this work is a systematic search for young, massive star candidates throughout the entire region within R ~ 2.5 pc of the black hole. Methods. The main criterion for the photometric identification of young, massive early-type stars is the lack of CO-absorption in the spectra. We used narrow-band imaging with VLT/ISAAC to search for young, massive stars within ~2.5 pc of Sgr A*. Results. We have found 63 early-type star candidates at R 0.5pc. The surface number density profile of the young, massive star candidates can be well fit by a single power-law, with Gamma = 1.6 +- 0.17 at R < 2.5 pc, which is significantly steeper than that of the late-type giants that make up the bulk of the observable stars in the NSC. Intriguingly, this power-law is consistent with the power-law that describes the surface density of young, massive stars in the same brightness range at R < 0.5 pc. Conclusions. The finding of a significant number of newly identified early-type star candidates at the Galactic center suggests that young, massive stars can be found throughout the entire cluster which may require us to modify existing theories for star formation at the Galactic center. Follow-up studies are needed to improve the existing data and lay the foundations for a unified theory of star formation in the Milky Way's NSC.
The Abdominal Circulatory Pump

Blood in the splanchnic vasculature can be transferred to the extremities. We quantified such blood shifts in normal subjects by measuring trunk volume by optoelectronic plethysmography, simultaneously with changes in body volume by whole body plethysmography during contractions of the diaphragm and abdominal muscles. Trunk volume changes with blood shifts, but body volume does not so that the blood volume shifted between trunk and extremities (Vbs) is the difference between changes in trunk and body volume. This is so because both trunk and body volume change identically with breathing and gas expansion or compression. During tidal breathing Vbs was 50–75 ml with an ejection fraction of 4–6% and an output of 750–1500 ml/min. Step increases in abdominal pressure resulted in rapid emptying presumably from the liver with a time constant of 0.61±0.1SE sec. followed by slower flow from non-hepatic viscera. The filling time constant was 0.57±0.09SE sec. Splanchnic emptying shifted up to 650 ml blood. With emptying, the increased hepatic vein flow increases the blood pressure at its entry into the inferior vena cava (IVC) and abolishes the pressure gradient producing flow between the femoral vein and the IVC inducing blood pooling in the legs. The findings are important for exercise because the larger the Vbs the greater the perfusion of locomotor muscles. During asystolic cardiac arrest we calculate that appropriate timing of abdominal compression could produce an output of 6 L/min. so that the abdominal circulatory pump might act as an auxiliary heart.
The Microcirculation in Venous Hypertension

Venous ulceration is a common problem in western countries and results in large costs to healthcare systems. A number of hypotheses of the mechanisms of development of venous ulceration have been advanced, but this question has not been fully resolved. In recent years research effort has focused on the microcirculation of the skin and many methods of investigation have been employed to study this. Some of the principal findings described in published work are reviewed in this article. It seems unlikely from the available evidence that venous ulceration is attributable solely to failure of diffusion of oxygen and other small nutritional molecules to the tissues of the skin. The microvascular changes in the skin are characterised by activated endothelium and perivascular inflammatory cells. It is much more likely that leucocytes attach themselves to the cutaneous microcirculation, become activated and produce endothelial injury. Repeated over many months or years, this chronic inflammatory process leads to be tissues changes of lipodermatosclerosis. Although there is evidence of leucocyte involvement in the pathogenesis of venous ulceration, the exact mechanisms remain to be resolved. Improved treatment for patients may be devised once a better understanding of the basic causes of this condition has been reached.
ACTIVITY-BASED STUDENT INDUCTION, MOTIVATION, PERFORMANCE AND PROFESSIONAL SOCIALISATION: A CASE STUDY

1 Norrie S. Edward, The Robert Gordon University, School of Engineering, Aberdeen, n.edward@rgu.ac. uk 2 June C. R.Middleton, The Robert Gordon University, Faculty of Science and Technology, Aberdeen, j.c. middleton@rgu.ac. uk Concern about high early attrition rates from of our engineering courses led to an innovative team, contextual induction process. We sought to introduce the students to the skills needed to survive the first year and alleviate their concerns about the demands of their course. Those with higher perceptions of the process and with strong identification with engineering were expected to perform better subsequently. We correlated measures of this commitment and “grade point scores” of entrants as a measure of ability with performance. Induction was well received by students. Neither their perceptions of the programme, their estimates of their gain in technical knowledge nor other measures, however, was significantly related with subsequent performance. These negative results have led us to concentrate on the academic and pastoral support systems. During induction students had a facilitator and used experts but were forced immediately into autonomous learning. Despite our findings we remain convinced that commitment to the profession will be motivational and that our induction can encourage this commitment.
Microlensing of Pulsar Radiation in the Galactic Center

We investigate the possibility of identifying massive objects (lenses) in the Galactic Center region (GC) by means of pulsar timing. The well known intensity change due to microlensing is found to be less important. For typical stellar masses, the ux magniication can be signiicant only if the lens passes very close to the pulsar{ Earth axis. We show that in the case of a pulsar the time varying travel-time delay, which is observable because of the pulsating nature of pulsar radiation, is a much more powerful tool to investigate mass distributions in the GC. We nd that a travel-time delay is measurable even for rather large distances between the lens and the pulsar{ Earth axis. The time varying travel-time delay can be used to determine the mass of the lens and the ratio of the transverse velocity to the minimum impact parameter. Based on Monte Carlo simulations of synthetic data sets we give the expected accuracies in the parameter determination for various masses. We argue that pulsars found behind the very center of our Galaxy would provide an excellent opportunity to test the mass distribution in the Galactic nucleus, and therefore to distinguish between a super massive black hole (SMBH) and a super-dense star cluster (SDSC) within the central 0.1 pc.
The Provision of Services, Interest Margins and Loan Pricing in European Banking

This paper assesses the implications on bank interest margins of the expansion into non- traditional fee-based activities in European banking. We use a sample of 602 European commercial and cooperative banks from 1996 to 2002 and consider the total income shares of trading income and commission and fee income as measures of product diversification to explore loan pricing. Our results show that a higher income share from commission and fee activities is associated with lower margins and lower lending rates but that there is no link with trading activities. For banks exhibiting a higher share of commission and fee income there is a weaker link between the rate they charge on loans and borrower default risk. The hypothesis that banks use loans as a loss leader altering default screening and monitoring activities and consequently risk pricing cannot be rejected.
Springer theory in braid groups and the Birman-Ko-Lee monoid

We state a conjecture about centralizers of certain roots of central elements in braid groups, and check it for braid groups of type A, B, G(d, 1, r) and a couple of other cases. Our proof makes use of results from Birman-Ko-Lee, of which we give a new intrinsic account.
Visual Recognition of Ancient Inscriptions Using Convolutional Neural Network and Fisher Vector

By bringing together the most prominent European institutions and archives in the field of Classical Latin and Greek epigraphy, the EAGLE project has collected the vast majority of the surviving Greco-Latin inscriptions into a single readily-searchable database. Text-based search engines are typically used to retrieve information about ancient inscriptions (or about other artifacts). These systems require that the users formulate a text query that contains information such as the place where the object was found or where it is currently located. Conversely, visual search systems can be used to provide information to users (like tourists and scholars) in a most intuitive and immediate way, just using an image as query. In this article, we provide a comparison of several approaches for visual recognizing ancient inscriptions. Our experiments, conducted on 17, 155 photos related to 14, 560 inscriptions, show that BoW and VLAD are outperformed by both Fisher Vector (FV) and Convolutional Neural Network (CNN) features. More interestingly, combining FV and CNN features into a single image representation allows achieving very high effectiveness by correctly recognizing the query inscription in more than 90% of the cases. Our results suggest that combinations of FV and CNN can be also exploited to effectively perform visual retrieval of other types of objects related to cultural heritage such as landmarks and monuments.
Measuring Liquidity Mismatch in the Banking Sector

This paper implements a liquidity measure, “Liquidity Mismatch Index (LMI),” to gauge the mismatch between the market liquidity of assets and the funding liquidity of liabilities. We construct the LMIs for 2882 bank holding companies during 2002-2014 and investigate the time-series and cross-sectional patterns of banks' liquidity and liquidity risk. Aggregate banking sector liquidity worsens from +$4 trillion before the crisis to -$6 trillion in 2008, and reverses back to the pre-crisis level in 2009. We also show how a macro-prudential liquidity stress test can be conducted with the LMI metric, and that such a stress test could have revealed the fragility of the banking system in early 2007. In the cross section, we find that banks with more ex-ante liquidity mismatch have a higher stock-market crash probability and are more likely to borrow from the government during the financial crisis. Thus the LMI measure is informative regarding both individual bank liquidity risk as well as the liquidity risk of the entire banking system. We compare the LMI measure of liquidity to other measures such as Basel III's liquidity coverage ratio and net stable funding ratio, and show that LMI performs better in many dimensions. The outperformance of LMI partially results from the contract-specific time-varying liquidity sensitivity weights which are driven by market prices.
Human reliability analysis in healthcare: A review of techniques

Whilst Human Reliability Analysis (HRA) has been well-accepted and integrated into the safety management process in other industries, the application of such error analysis techniques to the problem of complication and reaction to treatment and the associated risks in healthcare is rare. Though the scarcity of HRA techniques in health-care is likely to be due in some part to the safety culture, much is likely to be due to a lack of awareness of the usefulness of the techniques and their applicability to the problem of human error in the clinical context. This review attempts to look at the popular HRA techniques used in high-reliability industries, such as petro-chemical, nuclear and aviation, and consider their feasibility for use in healthcare. Techniques vary in their scope and have been grouped into those that focus on: data collection, task description, task simulation, human error identification and analysis, and human error quantification. Techniques may cover one or more of these aspects, for example, THERP, HEART and SHERPA include both human error identification and analysis, and human error quantification tools. While some areas of healthcare have used certain HRA techniques, there is considerable scope to use others and to apply techniques to other aspects of healthcare not yet explored.
A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin

The human intestinal epithelium is rapidly and perpetually renewed as the descendants of multipotent stem cells located in crypts undergo proliferation, differentiation, and eventual exfoliation during a very well organized migration along the crypt to villus axis. The mechanisms that establish and maintain this balance between proliferation and differentiation are largely unknown. We have utilized HT-29 cells, derived from a human colon adenocarcinoma, as a model system for identifying gene products that may regulate these processes. Proliferating HT-29 cells cultured in the absence of glucose (e.g., using inosine as the carbon source) have some of the characteristics of undifferentiated but committed crypt epithelial cells while postconfluent cells cultured in the absence of glucose resemble terminally differentiated enterocytes or goblet cells. A cDNA library, constructed from exponentially growing HT-29 cells maintained in inosine-containing media, was sequentially screened with a series of probes depleted of sequences encoding housekeeping functions and enriched for intestine-specific sequences that are expressed in proliferating committed, but not differentiated, epithelial cells. Of 100,000 recombinant phage surveyed, one was found whose cDNA was derived from an apparently gut-specific mRNA. It encodes a 316 residue, 35,463-D protein that is a new member of the annexin/lipocortin family. Other family members have been implicated in regulation of cellular growth and in signal transduction pathways. RNA blot and in situ hybridization studies indicate that the gene encoding this new annexin exhibits region-specific expression along both axes of the human gut: (a) highest levels of mRNA are present in the jejunum with marked and progressive reductions occurring distally; (b) its mRNA appears in crypt-associated epithelial cells and increases in concentration as they exit the crypt. Villus-associated epithelial cells continue to transcribe this gene during their differentiation/translocation up the villus. Immunocytochemical studies reveal that the intestine-specific annexin (ISA) is associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes. In polarized enterocytes, the highest concentrations of ISA are found at the apical compared to basolateral membrane. In vitro studies using an octapeptide derived from residues 2-9 of the primary translation product of ISA mRNA and purified myristoyl-CoA:protein N-myristoyltransferase suggested that it is N-myristoylated. In vivo labeling studies confirmed that myristate is covalently attached to ISA via a hydroxylamine resistant amide linkage. The restricted cellular expression and acylation of ISA distinguish it from other known annexins. (ABSTRACT TRUNCATED AT 400 WORDS)
Monocytes Play an IL-12-Dependent Crucial Role in Driving Cord Blood NK Cells to Produce IFN-g in Response to Trypanosoma cruzi

We previously reported that foetuses congenitally infected with Trypanosoma cruzi, the agent of Chagas disease, mount an adult-like parasite-specific CD8+ T-cell response, producing IFN-g, and present an altered NK cell phenotype, possibly reflecting a post-activation state supported by the ability of the parasite to trigger IFN-g synthesis by NK cells in vitro. We here extended our knowledge on NK cell activation by the parasite. We compared the ability of T. cruzi to activate cord blood and adult NK cells from healthy individuals. Twenty-four hours co-culture of cord blood mononuclear cells with T. cruzi trypomastigotes and IL-15 induced high accumulation of IFN-g transcripts and IFN-g release. TNF-a, but not IL-10, was also produced. This was associated with up-regulation of CD69 and CD54, and down-regulation of CD62L on NK cells. The CD56bright NK cell subset was the major IFN-g responding subset (up to 70% IFN-g-positive cells), while CD56dim NK cells produced IFN-g to a lesser extent. The response points to a synergy between parasites and IL-15. The neonatal response, observed in all newborns, remained however slightly inferior to that of adults. Activation of IL-15-sensitized cord blood NK cells by the parasite required contacts with live/intact parasites. In addition, it depended on the engagement of TLR-2 and 4 and involved IL-12 and cross-talk with monocytes but not with myeloid dendritic cells, as shown by the use of neutralizing antibodies and cell depletion. This work highlights the ability of T. cruzi to trigger a robust IFN-g response by IL-15-sensitized human neonatal NK cells and the important role of monocytes in it, which might perhaps partially compensate for the neonatal defects of DCs. It suggests that monocyte- and IL-12- dependent IFN-g release by NK cells is a potentially important innate immune response pathway allowing T. cruzi to favour a type 1 immune response in neonates.
The millimeter-wave continuum spectrum of Centaurus A and its nucleus

Aims. We study the radio emission mechanism of the FR-I AGN NGC 5128 (Centaurus A). Methods. We determine the centimeter and millimeter continuum spectrum of the whole Centaurus A radio source and measure at frequencies between 86 GHz (3.5 mm) and 345 GHz (0.85 mm) the continuum emission from the active radio galaxy nucleus at various times between 1989 and 2005. Results. The integral radio source spectrum becomes steeper at frequencies above 5 GHz, where the spectral index changes from alpha(low) = -0.70 to alpha(high) = -0.82. The SW outer lobe has a steeper spectrum than the NE middle and outer lobes (alpha = -1.0 vs. -0.6). Millimeter emission from the core of Centaurus A is variable, a variability that correlates appreciably better with the 20-200 keV X-ray variability than with 2-10 keV variability. Conclusions. In its quiescent state, the core has a spectral index alpha = -0.3, which steepens when the core brightens. The variability appears to be mostly associated with the inner nuclear jet components that have been detected in VLBI measurements. The densest nuclear components are optically thick below 45-80 GHz.
A new feature extraction method for identification of affected regions and diagnosis of cognitive disorders

Cognitive disorders like AD progressively disintegrate neurons and their interconnections in the brain; thus gradually deteriorating cognitive functions. Automated diagnosis is very important in the early diagnosis of cognitive disorders. Early diagnosis allows in taking measures helping the person to move on. Clinical diagnosis is inefficient as the symptoms start to manifest only after significant atrophy of the cortical structures. This makes management of the conditions difficult. Resent findings have revealed the potential of Neuroimaging as a highly effective tool in the early detection of these disorders as structural changes in the brain set in much before the manifestation of observable symptoms. The disorders are a reflection of degeneration of the cortical structures and hence can be detected by analysis of the structural images of the brain. Therefore, analysis of T1-weighted MRI has become a popular method of early diagnosis of AD. The work proposes a feature extraction method that enables simultaneous identification of the afflicted cortical structures and diagnosis of disorders. The method proposed is based on sparse logistic regression and linear discriminant analysis. The results obtained were better than or comparable with many of the works reported in literature.