Miracle-dz/UniFAR-FTUs huggingface dataset:
The romantic self and the politics of internet commercialization

This essay looks at some examples of ways that certain pre-existing imaginary forms of ‘selfhood’ have been culturally mapped onto historically pivotal moments in the Internet’s development. It focuses less on how technologies have shaped culture than on the reverse: on certain ways that culture has shaped society’s embrace of the Internet. What the Internet is and will come to be, the essay suggests, is partly a matter of who we expect to be when we sit down to use it. Specifically, it looks at two key examples of ways that certain pre-existing imaginary forms of selfhood – ways of understanding oneself as a self – have been culturally mapped onto historically pivotal moments in the Internet’s development: the initial explosion of the Internet in the early 1990s and its supporting ethos exemplified by Wired magazine, and the Open Source Movement in the late 1990s. The essay suggests that significant parts of the culture of computing have been not only individualist, but also composed of two distinct if intertwined strands of individualism, romantic and utilitarian, and that their difference has political significance. Like its ancestor, the 1960s counterculture, the case of the computer culture suggests that romantic individualism stands in a tangential relation to capitalist property relations (and the utilitarian ‘I’ they imply), sometimes working in concert with markets and privatization, as was the case in the early 1990s, and sometimes working to call them into question, as was the case towards the end of the 1990s.
Mobil's epideictic advocacy: “Observations” of Prometheus‐bound

Among “corporate rhetors,” none has been regarded as more creative and aggressive than Mobil Oil. This essay examines Mobil's use of “Observations"—half‐page Sunday newspaper magazine section ads—during the years of 1976–1980. The first focus is upon “Observations” as epideictic discourse developed in response to Mobil's 1975 rhetorical situation. Attention is then turned to examples of the discourse itself and a summary of 149 “Observations. ” Following the analysis are treatments of the identificational strategies used by Mobil and the Promethean myth which gives those strategies universal appeal. Finally, Mobil's “epideictic advocacy” is evaluated by the standards of effect, ethics, and art. Through “Observations” Mobil intends to be—like the Sunday newspaper—a part of America's afternoon.
Sex Differences in the Reinstatement of Methamphetamine Seeking after Forced Abstinence in Sprague-Dawley Rats

Preventing relapse to drug abuse is one of the struggles faced by clinicians in order to treat patients with substance use disorders (DSM-5). There is a large body of clinical evidence suggesting differential characteristics of the disorder in men and women, which is in line with preclinical findings as well. The aim of this study was to assess differences in relapse-like behavior in methamphetamine (METH) seeking after a period of forced abstinence, which simulates the real clinical situation very well. Findings from such study might add new insights in gender differences in relapse mechanisms to previous studies, which employ a classical drug or cue-induced reinstatement procedure following the extinction training. Adult male and female Sprague-Dawley rats were used in IV self-administration procedure conducted in operant boxes using nose-poke operandi (Coulborn Instruments, USA). Active nose-poke resulted in activation of the infusion pump to deliver one intravenous infusion of METH (0.08 mg/kg). After baseline drug intake was established (maintenance phase), a period of forced abstinence was initiated and rats were kept singly in their home cages for 14 days. Finally, one reinstatement session in operant boxes was conducted. Females were found to self-administer significantly lower dose of METH. The relapse rate was assessed as a number of active nose-pokes during the reinstatement session, expressed as a percentage of active nose-poking during the maintenance phase. Females displayed approximately 300% of active nose-pokes compared to 50% in males. This indicates higher vulnerability to relapse of METH seeking behavior in female rats. This effect was detected in all females, independently of current phase of their estrous cycle. Therefore, this paradigm using operant drug self-administration and reinstatement of drug-seeking after forced abstinence model can be used for preclinical screening for potential new anti-relapse medications specific for women.
Five-Day Intravascular Methotrexate Versus Biweekly Actinomycin-D in the Treatment of Low-Risk Gestational Trophoblastic Neoplasia: A Clinical Randomized Trial

Objectives Methotrexate (MTX) and Actinomycin-D (Act-D) are effective drugs used in the treatment of low-risk gestational trophoblastic neoplasia (LRGTNs). The aim of the present study was to compare intravenous (IV) MTX and IV Act-D in the treatment of LRGTNs. Materials and Methods Sixty-two patients with LRGTN were enrolled in a prospective randomized clinical trial between 2010 and 2013 in Moheb e Yas Hospital, Tehran University of Medical Sciences. Primary treatment regimens were IV MTX, 0.4 mg/kg daily for 5 days every 14 days (25 mg maximum daily dose), and IV Act-D, 1.25 mg/m2 (2 mg maximum dose) every 14 days. Results Thirty-two and 30 patients were enrolled to MTX and Act-D groups, respectively. Complete remission after receiving first-line chemotherapy was achieved in 79% of all cases, 80% in the Act-D group and 78.1% in the MTX group. Twenty percent of the Act-D patients and 21.9% of the MTX patients showed resistance to the first-line chemotherapy, of which 16.7% and 15.6% responded completely to the second-line monotherapy, respectively. Multiple drug therapy was needed in 3.3% of the Act-D group and 6.3% of the MTX group. We did not find any correlation between treatment response and beta–human chorionic gonadotropin level, uterine mass size, lung metastasis, antecedent pregnancy, and duration from diagnosis to treatment. Adverse effects were not statistically different between the 2 groups. Conclusions Single-agent chemotherapy in the treatment of LRGTNs resulted in an overall complete remission rate of 79%, 80% in the Act-D group and 78.1% in MTX group, with no statistically significant difference. Whereas this study represents an important step in comparing single-agent treatments, comparison of other regimens will be required to determine the optimal single-agent therapy.
Leveraging HIV Programming to Enhance Access to Noncommunicable Disease Care in Southern Botswana

Objective: The objective of this study was to assess whether HIV programming in southern Botswana could be leveraged to provide care for patients with noncommunicable diseases (NCDs). Methods: A retrospective analysis was performed to determine the spectrum and complexity of NCDs seen by HIV-focused outreach programming delivered between July 2011 and December 2013, to 9 facilities in southern Botswana. The association of HIV status and specific International Classification of Disease codes was examined using bivariate analysis. Results: Outreach HIV physicians recorded 926 outpatient consults involving 835 patients during the studied period. While 25% (n = 209) of patients seen were HIV infected, most patients were either HIV negative (49%, n = 410) or had an unknown HIV status (26%, n = 216). Noncommunicable disease referrals were as common at primary- and district-level facilities (90% [n = 459] versus 93% [n = 301]; P = .22). Conclusion: This study demonstrates how HIV programming in Botswana can be leveraged to improve access to specialist medical services for patients with NCDs.
MACI Scores of African American Males in a Forensic Setting: Are We Measuring What We Think We Are Measuring?

In this study, confirmatory factor analyses were used to examine scores on the Millon Adolescent Clinical Inventory (MACI) in adolescent, African American males in a forensic setting (N = 496; Mage = 15.96, SDage = 1.32). Results from the study do not support the model proposed by Millon and suggest the MACI may not yield valid or reliable scores in forensic populations of adolescent, African American males. Because MACI scores could be misleading in African American males, the authors argue that the MACI and other trait-scales not validated in this group be used with extreme caution—especially in settings where African Americans are disproportionately represented.
Infective endocarditis: a tertiary referral centre experience from Turkey.

INTRODUCTION We aimed to define the current characteristics of infective endocarditis (IE) in a part of Turkey. METHODS All patients who were hospitalized in our hospital with a diagnosis of IE between 2009 and 2014 were included in the study. Data were collected from archives records of all patients. Modified Duke criteria were used for diagnosis. RESULTS There were 85 IE cases during the study period. The mean age of patients was 52 years. Fourty eight of patients were males. Native valves involved in 47%, prostetic valves involved in 40% and pacemaker or ICD lead IE in 13% of patients. Mitral valve was the most common site of vegetationb (38%). The most common valvular pathology was mitral regurgitation. The most common predisposing factor was prosthetic valve disease (40%). Positive culture rate was 68%. Staphylococci were the most frequent causative microorganisms isolated (27%) followed by Streptococcus spp. (11%). In-hospital mortality rate was 36%. CONCLUSION In Turkey, IE occurs in relatively young patients. In high developed part of Turkey, prosthetic and dejenerative valve disease is taking the place of rheumatic valve disease as a predisposing factor. Surgery is an important factor for preventing mortality.
Observer-Based Adaptive Backstepping Consensus Tracking Control for High-Order Nonlinear Semi-Strict-Feedback Multiagent Systems

Combined with backstepping techniques, an observer-based adaptive consensus tracking control strategy is developed for a class of high-order nonlinear multiagent systems, of which each follower agent is modeled in a semi-strict-feedback form. By constructing the neural network-based state observer for each follower, the proposed consensus control method solves the unmeasurable state problem of high-order nonlinear multiagent systems. The control algorithm can guarantee that all signals of the multiagent system are semi-globally uniformly ultimately bounded and all outputs can synchronously track a reference signal to a desired accuracy. A simulation example is carried out to further demonstrate the effectiveness of the proposed consensus control method.
Effects of transitional bilingual education on Spanish-speaking preschoolers’ literacy and language development: Year 2 results

ABSTRACT Year 2 findings are reported from a longitudinal, experimental-control study involving 31 Spanish-speaking preschoolers (aged 38–48 months) randomly assigned to two Head Start classrooms. In Year 1, classrooms differed only in the language of instruction, with teachers using only Spanish in one classroom and only English in the other. In Year 2, an experimental transitional bilingual education (TBE) model was implemented, with English being gradually introduced in the TBE classroom until a ratio of 30:70 English-to-Spanish was achieved and Spanish being gradually introduced in the predominantly English (PE) classroom until a ratio of 70:30 English-to-Spanish was achieved. Year 2 results were consistent with Year 1, with the TBE classroom exceeding the PE classroom on all Spanish measures of language and literacy development and no significant differences favoring the PE classroom. Results also indicated that Year 2 trajectories were conditional on first-year effects, suggesting that sustained growth in dual language learner's early literacy may depend on early intervention among 3-year-old preschoolers.
The repatriation process – a realistic approach

Purpose – This paper aims to present how a realistic view of the situation for the repatriate can help companies increase the retention rate among this important group of employees. A complete understanding of the repatriation process is crucial to offering repatriating employees proper backing and moral support needed during the process.Design/methodology/approach – A thorough review of the literature on repatriation is carried out to present a repatriation process model and a number of research propositions.Findings – This paper suggests that by focusing on motives and individuals' experience of the repatriation process, researchers and practitioners will be better able to understand the measures and support needed in the repatriation process to increase the retention of an organization's repatriated employees.Research limitations/implications – Suggestions for future research include a test of propositions by a survey, a longitudinal study of repatriates and closer look at the variables of motives and .
Enterprise architecture, IT effectiveness and the mediating role of IT alignment in US hospitals

Despite the possible benefits of implementing healthcare information technologies, successful implementation of effective healthcare information technology is constrained by cultural and regulatory concerns and technical obstacles encountered when establishing or upgrading an organisation's enterprise infrastructure. In this paper, we advance Ross' four‐stage model of enterprise architecture maturity as a valuable IT resource for helping healthcare organisations sustain a competitive advantage. We use partial least squares (PLS) structural equation modelling to analyse survey data from 164 US hospitals at different stages of EA maturity. Our results provide evidence that enterprise architecture maturity directly influences the effectiveness of hospitals' IT resources for achieving strategic goals. Further, enterprise architecture maturity indirectly influences the effectiveness of IT resources when IT alignment is incorporated as a mediating variable. We discuss the implications of our findings for research and practice and suggest opportunities for future research.
Stronger autonomic response accompanies better learning: A test of Damasio's somatic marker hypothesis

According to Damasio's (1994, 1999) somatic marker hypothesis (SMH), positive and negative events are “marked” by bodily feelings. These markers aid future adaptive learning by producing signals to warn against or affirm behavioural options. An implicit assumption of the SMH is that the stronger the signal is, the stronger the resultant behaviour will be. In this study, we tested 30 healthy women on a gambling task (Bechara, Damasio, Damasio, & Anderson, 1994), while measuring skin conductance responses. For half of the participants, real money was used, and for half, fake money was used. Success on the task was positively correlated with anticipatory autonomic response, with no difference in pattern between real and fake money conditions. The results show clear support for Damasio's SMH, and suggest that it can be used to predict learning performance within a healthy population.
The NDR Kinase DBF-2 Is Involved in Regulation of Mitosis, Conidial Development, and Glycogen Metabolism in Neurospora crassa

ABSTRACT Neurospora crassa dbf-2 encodes an NDR (nuclear Dbf2-related) protein kinase, homologous to LATS1, a core component of the Hippo pathway. This pathway plays important roles in restraining cell proliferation and promoting apoptosis in differentiating cells. Here, we demonstrate that DBF-2 is involved in three fundamental processes in a filamentous fungus: cell cycle regulation, glycogen biosynthesis, and conidiation. DBF-2 is predominantly localized to the nucleus, and most (approximately 60%) dbf-2 null mutant nuclei are delayed in mitosis, indicating that DBF-2 activity is required for properly completing the cell cycle. The dbf-2 mutant exhibits reduced basal hyphal extension rates accompanied by a carbon/nitrogen ratio-dependent bursting of hyphal tips, vast glycogen leakage, defects in aerial hypha formation, and impairment of all three asexual conidiation pathways in N. crassa. Our findings also indicate that DBF-2 is essential for sexual reproduction in a filamentous fungus. Defects in other Hippo and glycogen metabolism pathway components (mob-1, ccr-4, mst-1, and gsk-3) share similar phenotypes such as mitotic delay and decreased CDC-2 (cell division cycle 2) protein levels, massive hyphal swellings, hyphal tip bursting, glycogen leakage, and impaired conidiation. We propose that DBF-2 functions as a link between Hippo and glycogen metabolism pathways.
Prediction of Extracellular Matrix Proteins Based on Distinctive Sequence and Domain Characteristics

Extracellular matrix (ECM) proteins are secreted to the exterior of the cell, and function as mediators between resident cells and the external environment. These proteins not only support cellular structure but also participate in diverse processes, including growth, hormonal response, homeostasis, and disease progression. Despite their importance, current knowledge of the number and functions of ECM proteins is limited. Here, we propose a computational method to predict ECM proteins. Specific features, such as ECM domain score and repetitive residues, were utilized for prediction. Based on previously employed and newly generated features, discriminatory characteristics for ECM protein categorization were determined, which significantly improved the performance of Random Forest and support vector machine (SVM) classification. We additionally predicted novel ECM proteins from non-annotated human proteins, validated with gene ontology and earlier literature. Our novel prediction method is available at biosoft.kaist. ac.kr/ecm.
Leaders of progressions in wild mixed‐species troops of saddleback (Saguinus fuscicollis) and mustached tamarins (S. mystax), with emphasis on color vision and sex

Leadership of travel progression is an important aspect of group living. It is widely believed that trichromacy evolved to facilitate the detection and selection of fruit in the dappled light of a forest. Further, it has been proposed that in New World primate species, which typically contain a range of color vision phenotypes, at least one female in a group will be trichromatic (i.e., having three types of visual pigment, in contrast to the two types of pigment found in dichromatic individuals) and will lead the group to fruiting trees. We examine progression leadership within two wild mixed‐species troops of saddleback (Saguinus fuscicollis) and mustached (Saguinus mystax) tamarins over a complete year. As whole units, the mixed‐species troops were most frequently led by a mustached tamarin. This is the first time that mixed‐species group leadership and individual leadership have been quantified in these tamarin species. In terms of single‐species intragroup leadership, neither the visual status (dichromatic or trichromatic) nor the sex of individuals had a consistent effect across species. Saddleback tamarin groups were led by males more frequently than females, while evidence suggests that mustached tamarins may be female‐led. The notion that all groups contain at least one trichromatic female that leads the troop to feeding trees was not supported. Am. J. Primatol. 61:145–157, 2003. © 2003 Wiley‐Liss, Inc.
The Rhetoric and Reality of Structured Tourism Work Experiences: A Social Representational Analysis

This paper reports on a study which explored the social representations of structured work experience (SWE) placements in university-based tourism education held by students, academic work placement coordinators, and industry professionals, and portrayed in public presentations of university tourism curricula. Social representations can be defined as everyday or lay theories about social phenomena. The paper explores the nature of the every day theories held by these different groups of actors. In particular, the analysis focused on perceptions of why structured work experiences are a necessary component of tourism education and the perceived benefits that such educational activities can provide. The analysis is based on a series of semi-structured interviews with academic coordinators, a semi-structured survey of industry professionals or placement hosts, a survey of students in one Australian tourism management programme and a content analysis of the public information about structured work experiences available on the websites of 25 universities from North America, the United Kingdom and Australia. Two representations were identified—one based on emphasizing skill building and one on reducing risk for employers and students. The data shows that the skill building representation exists only partially amongst academics and not at all amongst the other actors and this lack of specificity, and the fact that it is only held by academics, contributes to the range of problems that have been associated with SWEs. The second representation about risk is the one that closely connects students and employers and offers the best opportunities for reducing the operational problems of SWEs.
Use of peptides from p21 (Waf1/Cip1) to investigate PCNA function in Xenopus egg extracts.

Cell-free systems derived from unfertilized Xenopus eggs have been particularly informative in the study of the regulation and biochemistry of DNA replication. We have developed a Xenopus-based system to analyze proliferating cell nuclear antigen (PCNA)-specific effects on the functional properties of egg extracts. To do this, we have coupled peptides derived from p21 (Waf1/Cip1) to beads and used these to deplete PCNA from Xenopus egg extracts. The effect on various aspects of DNA replication can be analyzed after the readdition of PCNA and other purified proteins. Using this system, we have shown that replication of single-stranded M13 DNA is entirely dependent upon PCNA. By adding exogenous T7 DNA polymerase to PCNA-depleted extracts, we have uncoupled processive DNA replication from PCNA activity and so created an experimental system to analyze the dependence of postreplicative processes on PCNA function. We have shown that successful chromatin assembly is specifically dependent on PCNA. However, systems for analyzing the far more complex mechanisms required for the replication of nuclear double-stranded DNA have proved so far to be refractory to specific PCNA depletion.
Assessing the quality of American doctoral program faculty in criminology and criminal justice, 1991–1995

This article assesses the quality of 299 faculty in 20 American doctoral programs in criminology and criminal justice by counting the number of citations of their work in six major American criminology and criminal justice journals published between 1991 and 1995. The University of Maryland, the University of Cincinnati, Rutgers University, and SUNY-Albany were the institutions with most citations. The individual faculty members most often cited were Francis T. Cullen (University of Cincinnati), Raymond Paternoster, Lawrence W. Sherman and Douglas A. Smith (all University of Maryland). The majority of the most-cited scholars in these six journals, however, were not members of criminology or criminal justice departments.
The Elephant in the Room: The Impact of Labor Obligations on Credit Markets

We show that labor market frictions are first-order for understanding credit markets. Wage growth and labor share forecast aggregate credit spreads and debt growth as well as or better than alternative predictors. They also predict credit risk and debt growth in a cross section of international firms. Finally, high labor share firms choose lower financial leverage. A model with labor market frictions and risky long-term debt can explain these findings, and produce large credit spreads despite realistically low default probabilities. This is because precommitted payments to labor make other committed payments (i.e., interest) riskier. (JEL D33, E23, E24, E25, E44, F23, G32)