Miracle-dz/UniFAR-FTUs huggingface dataset:
Glassbox: Dynamic Analysis Platform for Malware Android Applications on Real Devices

Android is the most widely used smartphone OS with 82.8% market share in 2015. It is therefore the most widely targeted system by malware authors. Researchers rely on dynamic analysis to extract malware behaviors and often use emulators to do so. However, using emulators lead to new issues. Malware may detect emulation and as a result it does not execute the payload to prevent the analysis. Dealing with virtual device evasion is a never-ending war and comes with a non-negligible computation cost. To overcome this state of affairs, we propose a system that does not use virtual devices for analysing malware behavior. Glassbox is a functional prototype for the dynamic analysis of malware applications. It executes applications on real devices in a monitored and controlled environment. It is a fully automated system that installs, tests and extracts features from the application for further analysis. We present the architecture of the platform and we compare it with existing Android dynamic analysis platforms. Lastly, we evaluate the capacity of Glassbox to trigger application behaviors by measuring the average coverage of basic blocks on the AndroCoverage dataset. We show that it executes on average 13.52% more basic blocks than the Monkey program.
Accuracy of musculoskeletal imaging for the diagnosis of polymyalgia rheumatica: systematic review

Objectives To review the evidence for accuracy of imaging for diagnosis of polymyalgia rheumatica (PMR). Methods Searches included MEDLINE, EMBASE and PubMed. Evaluations of diagnostic accuracy of imaging tests for PMR were eligible, excluding reports with <10 PMR cases. Two authors independently extracted study data and three authors assessed methodological quality using modified QUADAS-2 criteria. Results 26 studies of 2370 patients were evaluated: 10 ultrasound scanning studies; 6 MRI studies; 1 USS and MRI study; 7 18-fluorodeoxyglucose-positron emission tomography (PET) studies; 1 plain radiography and 1 technetium scintigraphy study. In four ultrasound studies, subacromial-subdeltoid bursitis had sensitivity 80% (95% CI 55% to 93%) and specificity 68% (95% CI 60% to 75%), whereas bilateral subacromial-subdeltoid bursitis had sensitivity 66% (95% CI 43% to 87%) and specificity 89% (95% CI 66% to 97%). Sensitivity for ultrasound detection of trochanteric bursitis ranged from 21% to 100%. In four ultrasound studies reporting both subacromial-subdeltoid bursitis and glenohumeral synovitis, detection of subacromial-subdeltoid bursitis was more accurate than that of glenohumeral synovitis (p=0.004). MRI and PET/CT revealed additional areas of inflammation in the spine and pelvis, including focal areas between the vertebrae and anterior to the hip joint, but the number of controls with inflammatory disease was inadequate for precise specificity estimates. Conclusions Subacromial-subdeltoid bursitis appears to be the most helpful ultrasound feature for PMR diagnosis, but interpretation is limited by study heterogeneity and methodological issues, including variability in blinding and potential bias due to case–control study designs. Recent MRI and PET/CT case–control studies, with blinded readers, yielded promising data requiring validation within a diagnostic cohort study.
Catalytic Effects in Lithium–Sulfur Batteries: Promoted Sulfur Transformation and Reduced Shuttle Effect

Lithium–sulfur (Li–S) battery has emerged as one of the most promising next‐generation energy‐storage systems. However, the shuttle effect greatly reduces the battery cycle life and sulfur utilization, which is great deterrent to its practical use. This paper reviews the tremendous efforts that are made to find a remedy for this problem, mostly through physical or chemical confinement of the lithium polysulfides (LiPSs). Intrinsically, this “confinement” has a relatively limited effect on improving the battery performance because in most cases, the LiPSs are “passively” blocked and cannot be reused. Thus, this strategy becomes less effective with a high sulfur loading and ultralong cycling. A more “positive” method that not only traps but also increases the subsequent conversion of LiPSs back to lithium sulfides is urgently needed to fundamentally solve the shuttle effect. Here, recent advances on catalytic effects in increasing the rate of conversion of soluble long‐chain LiPSs to insoluble short‐chain Li2S2/Li2S, and vice versa, are reviewed, and the roles of noble metals, metal oxides, metal sulfides, metal nitrides, and some metal‐free materials in this process are highlighted. Challenges and potential solutions for the design of catalytic cathodes and interlayers in Li–S battery are discussed in detail.
Performance of hand-held electrocardiogram devices to detect atrial fibrillation in a cardiology and geriatric ward setting.

I read the article on the performance of two hand-held electrocardiogram devices for detecting atrial fibrillation by Desteghe et al. 1 with great interest. As the founder of AliveCor, I supplied the senior author Dr. Heidbuchel with the AliveCor device, as it was neither approved nor available for sale in Belgium at that time, and his group understood that it could be used only for clinical research purposes. It had been approved by the FDA and EC …
Chest Compressions Cause Recurrence of Ventricular Fibrillation After the First Successful Conversion by Defibrillation in Out-of-Hospital Cardiac Arrest

Background—Unlike Resuscitation Guidelines (GL) 2000, GL2005 advise resuming cardiopulmonary resuscitation (CPR) immediately after defibrillation. We hypothesized that immediate CPR resumption promotes earlier recurrence of ventricular fibrillation (VF). Methods and Results—This study used data of a prospective per-patient randomized controlled trial. Automated external defibrillators used by first responders were randomized to either (1) perform postshock analysis and prompt rescuers to a pulse check (GL2000), or (2) resume CPR immediately after defibrillation (GL2005). Continuous recordings of ECG and impedance signals were collected from all patients with an out-of-hospital cardiac arrest to whom a randomized automated external defibrillator was applied. We included patients with VF as their initial rhythm in whom CPR onset could be determined from the ECG and impedance signals. Time intervals are presented as median (Q1-to-Q3). Of 361 patients, 136 met the inclusion criteria: 68 were randomly assigned to GL2000 and 68 to GL2005. Rescuers resumed CPR 30 (21-to-39) and 8 (7-to-9) seconds, respectively, after the first shock that successfully terminated VF (P<0.001); VF recurred after 40 (21-to-76) and 21 (10-to-80) seconds, respectively (P=0.001). The time interval between start of CPR and VF recurrence was 6 (0-to-67) and 8 (3-to-61) seconds, respectively (P=0.88). The hazard ratio for VF recurrence in the first 2 seconds of CPR was 15.5 (95% confidence interval, 5.63 to 57.7) compared with before CPR resumption. After more than 8 seconds of CPR, the hazard of VF recurrence was similar to before CPR resumption. Conclusions—Early CPR resumption after defibrillation causes early VF recurrence. Clinical Trial Registration—clinicaltrials.gov Identifier: ISRCTN72257677.
Modelling drum patterns with weighted finite-state transducers

In this paper, we present an approach to model bar length drum patterns with weighted finite-state transducers. Motivated by the existing algorithms for speech recognition, we discuss similarities to music, by considering a bar as word and the progression of bars as language. However, in contrast to speech, music has special characteristics, like metrical regularity and multiple notes at one point in time, which have to be taken into account. We use MIDI data to retrieve the drum notes for every bar, which are the input for the training of the WFST models. Once the models are trained, they are used to automatically recognize drum patterns and their time signature in a sequence of unknown drum notes. We present an experiment on symbolic genre classification to demonstrate the principle of operation, training and recognition. It shows that the sequence of drum notes is representative for the four genres: Rumba, Samba, Tango and Waltz leading to a genre recognition rate of 88.9%±2.8%. Applications that could benefit from this approach include drum loop organization, drum note transcription, music similarity and genre detection.
Physico‐Mechanical Properties of Biodegradable Starch Nanocomposites

Nanocomposites of cassava starch reinforced with waxy starch nanocrystals were prepared. They showed a 380% increase of the rubbery storage modulus (at 50 °C) and a 40% decrease in the water vapor permeability. X-ray spectra show that the composite was more amorphous than the neat matrix, which was attributed to higher equilibrium water content in the composites. TGA confirmed this result and its thermal derivative suggested the formation of hydrogen bonding between glycerol and the nanocrystals. The reinforcing effect of starch nanocrystals was attributed to strong filler/matrix interactions due to the hydrogen bonding. The decrease of the permeability suggests that the nanocrystals were well dispersed, with few filler/filler interactions.
Critical appraisal of the role of fingolimod in the treatment of multiple sclerosis

This review summarizes Phase III clinical trial data available for fingolimod. The main purpose is to evaluate the benefit-risk profile of fingolimod, the first oral compound available for treatment of multiple sclerosis (MS) and just recently approved by the European authorities. The authors place this evaluation in the context of the known safety and efficacy profile of established compounds for therapy of MS to outline the current and future potential of fingolimod. The authors conclude that only long-term safety data from post-marketing surveillance plans, together with additional head-to-head studies, would allow evidence-based treatment decisions. Furthermore, risk-profile analyses including patient history, exposure data to certain pathogens, and genetic analyses may potentially help to choose the right drug for individual patients in the future. Until these approaches toward an individualized medicine have been validated, treatment decisions for one or the other compound will have to be based partly on class IV evidence. Therefore, a close dialog with the well-informed patient, secured by effective risk mitigation plans, is required to choose the compound.
Collective motions in HIV-1 reverse transcriptase: examination of flexibility and enzyme function.

In order to study the inferences of structure for mechanism, the collective motions of the retroviral reverse transcriptase HIV-1 RT (RT) are examined using the Gaussian network model (GNM) of proteins. This model is particularly suitable for elucidating the global dynamic characteristics of large proteins such as the presently investigated heterodimeric RT comprising a total of 982 residues. Local packing density and coordination order of amino acid residues is inspected by the GNM to determine the type and range of motions, both at the residue level and on a global scale, such as the correlated movements of entire subdomains. Of the two subunits, p66 and p51, forming the RT, only p66 has a DNA-binding cleft and a functional polymerase active site. This difference in the structure of the two subunits is shown here to be reflected in their dynamic characteristics: only p66 has the potential to undergo large-scale cooperative motions in the heterodimer, while p51 is essentially rigid. Taken together, the global motion of the RT heterodimer is comprised of movements of the p66 thumb subdomain perpendicular to those of the p66 fingers, accompanied by anticorrelated fluctuations of the RNase H domain and p51 thumb, thus providing information about the details of one processivity mechanism. A few clusters of residues, generally distant in sequence but close in space, are identified in the p66 palm and connection subdomains, which form the hinge-bending regions that control the highly concerted motion of the subdomains. These regions include the catalytically active site and the non-nucleoside inhibitor binding pocket of p66 polymerase, as well as sites whose mutations have been shown to impair enzyme activity. It is easily conceivable that this hinge region, indicated by GNM analysis to play a critical role in modulating the global motion, is locked into an inactive conformation upon binding of an inhibitor. Comparative analysis of the dynamic characteristics of the unliganded and liganded dimers indicates severe repression of the mobility of the p66 thumb in RT's global mode, upon binding of non-nucleoside inhibitors.
Group provisioning limits sharing conflict among nestlings in joint-nesting Taiwan yuhinas

Offspring often compete over limited available resources. Such sibling competition may be detrimental to parents both because it entails wasted expenditure and because it allows stronger offspring to obtain a disproportionate share of resources. We studied nestling conflict over food and its resolution in a joint-nesting species of bird, the Taiwan yuhina (Yuhina brunneiceps). We show that adult yuhinas coordinate their feeding visits, and that this coordination limits competition among nestlings, leading to a ‘fairer’ division of resources. Transponder identification and video-recording systems were used to observe adult feeding and nestling begging behaviours. We found that: (i) yuhinas feed nestlings more often in large parties than in small parties; (ii) feeding events occurred non-randomly in bouts of very short intervals; and (iii) food distribution among nestlings was more evenly distributed, and fewer nestlings begged, during large-party feeding bouts compared with small-party feeding bouts. To our knowledge, this is the first study in a cooperative breeding species showing that adults can influence food allocation and competition among nestlings by coordinating their feeding visits. Our results confirm the hypothesis that the monopolizability of food affects the intensity of sibling competition, and highlight the importance of understanding the temporal strategies of food delivery.
Emerging Longitudinal Trends in Health Indicators for Rural Residents Participating in a Diabetes and Cardiovascular Screening Program in Northern Alberta, Canada

Background. Geographic isolation, poverty, and loss of culture/tradition contribute to “epidemic” rates of diabetes amongst indigenous Canadians. The Mobile Diabetes Screening Initiative travels to rural indigenous and other remote communities in Alberta to screen for diabetes and cardiovascular risk. We sought to examine risk factors longitudinally. Methods. Clinical and anthropometric measurements were undertaken for 809 adults (aged 20–91) between November 2003 and December 2009. For those who had more than one MDSi visit, trend estimates (actual changes) were calculated for body mass index (BMI), weight, waist circumference, hemoglobin A1c (A1c), total cholesterol, and blood pressure. Results. Among those without diabetes (N = 629), BMI and weight increased (P < .01) and blood pressure decreased (P < .05). For those with diabetes (N = 180), significant improvements (P < .05) were observed for all indicators except waist circumference. Conclusion. Improvements observed suggest that MDSi's model may effectively mediate some barriers and support subjects in managing their health.
Bile duct injury and bile leakage in laparoscopic cholecystectomy

Sir We would like to thank Messrs Dkon and Chetty for their interest and comments about granulomatous mastitis. There is no doubt that there is no ideal treatment for this difficult, rare and recurrent condition. Conservative treatment in the form of abscess drainage, aspiration and use of corticosteroids carries a high rate of recurrence and is associated with more complications. As surgeons, most of us have limited experience in managing this condition. Our follow-up for three of the patients who had excision of the masses and drainage of abscesses is less than 2 years since the last recurrence. The conclusion was made on this relatively short follow-up. At present, we feel that surgical treatment by excision of the mass and abscess drainage remains the treatment of choice and keep an open mind when considering alternative treatment as none seems to be ideal.
HCI over multiple screens

Mobile devices are playing an increasingly important role in leisure activities, including TV viewing. Broadcasters see this as an opportunity to enhance a TV programme through the provision of additional information to the 'second screen', but determining how to optimise this experience is one of the grand challenges currently facing content providers. Addressing this issue requires a detailed understanding of interaction with both the TV and the secondary device, but this new form of HCI, as much about passive consumption as active interaction, is not well represented by typical task-based paradigms. This paper describes experiments that use eye tracking to understand one of the key components of this new area of study - determining which device is currently receiving the user's attention - and discusses the considerable challenge of accurately monitoring attention while maintaining ecological validity.
THE BLOOD PARASITES OF ANURANS FROM COSTA RICA WITH REFLECTIONS ON THE TAXONOMY OF THEIR TRYPANOSOMES

During May 1997, specimens of 7 species of anurans, that included 5 Phrynohyas venulosa Laurenti, 5 Rana forreri Boulenger, 7 Rana vaillanti Brucchi, 6 Eleutherodactylus fitzingeri Schimdt, 4 Smilisca baudinii Duméril and Bibron, 1 Leptodactylus melanonotus, and 3 Bufo marinus Linneaus, from the Guanacaste Conservation Area, Costa Rica were examined for blood parasites. Their hematozoan fauna included intraerythrocytic and intraleukocytic icosahedral viruses, a rickettsia (Aegyptianella sp.), 2 species of Hepatozoon, Lankesterella minima, 2 unknown species of apicomplexans, 9 morphologically distinct types of trypanosomes, and 2 species of microfilariae. Rana vaillanti, the most aquatic species of frog, harbored the most species of parasites. Recent evidence indicates that morphological changes in the highly pleomorphic trypanosomes of anurans from different geographical regions have not kept pace with biochemical (isozyme) and molecular (DNA sequence) changes. Describing new species based solely on bloodstream trypomastigotes is discouraged. Additional criteria described herein should be applied when naming new species of anuran trypanosomes.
Response Inhibition and Measures of Psychopathology: A Dimensional Analysis

On the basis of Quay's (1988a, 1988b, 1993, 1997) model in which the Behavioral Inhibition System (BIS) and the Behavioral Activation System (BAS) are linked to various forms of child psychopathology, predictions were made regarding the relation between inhibitory control and two dimensions of psychopathology: externalizing and internalizing behavior. Inhibitory control was measured using two versions of Logan and Cowan's stop signal paradigm (1984; Logan, Cowan, & Davis, 1984; Osman, Kornblum, & Meyer, 1986, 1990). The primary outcome measure for the stop tasks was stop signal reaction time (SSRT) which measures the latency of the inhibition process. A positive relationship was predicted for externalizing behavior, whereas a negative relationship was predicted for internalizing behavior. A total of 42 non-clinical elementary school children, in the age range of 6 to 12 years, participated in the study. Externalizing behavior was positively related to response inhibition. Symptoms of ADHD seem to be better at predicting inhibitory functioning than symptoms of aggressive behavior disorders. Some support was found for a negative relation between internalizing behavior and inhibitory control. These findings support Quay's model and the discriminant validity of inhibitory control with regard to externalizing and internalizing behavior.
Idiopathic generalised epilepsy of adult onset: clinical syndromes and genetics

Objective: To study the clinical features and genetics of idiopathic generalised epilepsy (IGE) beginning in adult life. Methods: Consecutive patients with IGE, defined as generalised seizures with spike or polyspike and wave on EEG, were studied in the setting of a first seizure clinic where an early postictal EEG record is part of the protocol. Patients were divided into two groups: “classical IGE” with onset before 20 years and inclusive of all the IGE subsyndromes recognised by the international classification; and “adult onset IGE”, when seizure onset was at age 20 years or later. Seizure patterns, clinical features, and genetics of the adult onset group were examined. Results: Of 121 patients with an electro-clinical diagnosis of IGE, 34 (28%) were diagnosed as adult onset IGE. The seizure patterns in these 34 cases were tonic–clonic seizures + absences (3), tonic–clonic seizures + myoclonus (6), and tonic–clonic seizures alone (25). Tonic–clonic seizures were often precipitated by alcohol or sleep deprivation. The proportion of affected first and second degree relatives did not differ between the classical and adult onset IGE groups. Twenty adult onset cases were treated with sodium valproate, four with other antiepileptic drugs, and 10 were untreated. Follow up of 32 of the 34 cases (for 31 (22) months (mean (SD)) showed that tonic–clonic seizures recurred in eight patients: five with identified provocative factors and three without. Conclusions: Adult onset IGE is a relatively frequent and benign disorder. Seizures are usually provoked and are easy to control. Patients in this age group may often be misdiagnosed as having non-lesional partial epilepsy. Early postictal EEG and sleep deprivation studies may improve the detection of these patients. Pedigree analysis suggests that adult onset IGE, like classical IGE, has a genetic aetiology.
Data-Driven Product returns Prediction: a Cloud-based Ensemble Selection Approach

The number of product returns represents a considerable cost factor in e-commerce, especially in the apparel sector. The application of advanced information technologies and predictive analytics, enabling to capture and analyze massive amounts of user data, pave the way for a more efficient management of product returns and reverse logistics. However, we identify a lack of data-driven approaches in this area, especially regarding product returns prediction. In this paper, we present an ensemble selection approach for predicting product returns in the apparel sector. Computational experiments indicate that our approach produces satisfying results in terms of prediction quality. We further explore the correlation between sample sizes and computational times. Thereby, we demonstrate that the run-time increases exponentially when using more data records. To address heavy run-time overheads resulting from high processing and memory requirements of classifiers, we present a framework to embed ensemble selection processes into a highly scalable cloud environment. The framework explains the provisioning of cloud resources and parallelization of tasks according to ensemble selection processes. It further builds a basis for considering data streams, data splitting, and a dynamic adoption of changing customer behavior over time, which has not been considered in related work so far. The envisioned forecasting support system aids retailers in reducing product returns and increasing profit margins.
Thermodynamic data for steelmaking

１ Ｆｕｎｄａｍｅｎｔａｌ Ｔｈｅｏｒｙ ｏｆ Ｔｈｅｒｍｏｄｙｎａｍｉｃｓ ｆｏｒ Ｓｔｅｅｌｍａｋｉｎｇ（Ｔｈｅｒｍｏｄｙｎａｍｉｃｓ Ｌａｗｓ；Ｃｈｅｍｉｃａｌ Ｅｑｕｉｌｉｂｒｉｕｍ；ｓｏｌｕｔｉｏｎｓ） ２ Ｐｌａｉｎ Ｓｔｅｅｌ（Ａｂｓｔｒａｃｔ；Ｏｘｉｄｅ；Ｓｕｌｆｉｄｅ ほか） ３ Ｓｐｅｃｉａｌ Ｓｔｅｅｌｓ（Ａｂｓｔｒａｃｔ；Ｄａｔａ Ｓｈｅｅｔ；Ｃａｓ Ｓｔｕｄｉｅｓ ほか） ４ Ｏｘｉｄｅｓ ａｎｄ Ｉｎｃｌｕｓｉｏｎｓ（Ｏｘｉｄｅｓ；Ｃａｐａｃｉｔｙ；Ｓｕｌｆｒｉｄｅ ほか） ＡＰＰＥＮＤＩＸ Ｔｈｅｒｍｏｃｈｅｍｉｃａｌ Ｄａｔａ Ｃｏｌｌｅｃｔｅｄ ｉｎ “ＳＴＥＥＬＭＡＫＩＮＧ ＤＡＴＡ ＳＯＵＲＣＥ ＢＯＯＫ—ＲＥＶＩＳＥＤ ＥＤＩＴＩＯＮ—”（Ｒｅｃｏｍｍｅｎｄｅｄ Ｅｑｕｉｌｉｂｒｉｕｍ Ｖａｌｕｅｓ；Ｉｎｔｅｒａｃｔｉｏｎ Ｐａｒａｍｅｔｅｒｓ ｏｆ Ｅｌｅｍｅｎｔｓ ｉｎ Ｉｒｏｎ Ａｌｌｏｙｓ（ｅｊｉ））