Miracle-dz/UniFAR-FTUs huggingface dataset:
ATITUDES E PRÁTICAS PEDAGÓGICAS DE INCLUSÃO PARA O ALUNO COM AUTISMO

O Transtorno do Espectro Autista (TEA) é um transtorno do neurodesenvolvimento que compromete o aproveitamento escolar do aluno e o funcionamento adaptativo nos ambientes social e familiar. Os objetivos do estudo foram verificar conhecimentos sobre TEA, atitudes e práticas pedagógicas junto a alunos com o transtorno. Esse estudo teve desenho transversal descritivo com a participação de 217 professores da educação básica de uma rede pública. O instrumento de coleta de dados foi um questionário que averiguou conhecimentos sobre TEA, atitudes e práticas pedagógicas dos professores em sala de aula. Foram conduzidas análises descritivas de frequência e percentual. Os resultados indicaram que 84,8% dos profissionais reconheceram corretamente a presença de fatores associados a déficits de interação social, comportamento e comunicação, mas 30% cometeram erros na compressão dos fatores etiológicos. Considerando a opinião dos 102 (47%) professores participantes do estudo que tinham tido alunos com TEA em algum momento de sua atuação profissional, verificou-se em média que 70,56% deles concordavam com praticamente todas as ações educacionais e pedagógicas do Desenho Universal da Aprendizagem. Porém, a implementação dessas técnicas na prática não conseguia atingir o mesmo nível, já que essas ações eram utilizadas em média por 56,87% dos professores. O estudo possibilitou, a partir do relato dos professores, mapear integradamente aspectos essenciais que devem fazer parte de acomodações e/ou adaptações curriculares para alunos com TEA.
Technical Report : Semantic Annotation Platforms

Semantic annotation is a key component for the realization of the Semantic Web. The volume of existing and new documents on the Web makes manual annotation problematic. Semi-automatic methods have been designed to alleviate the burden, and these methods have begun to be implemented with Semantic Annotation Platforms (SAPs). SAPs provide services that support annotation, including ontologies, knowledge bases, information extraction methods, APIs, and user interfaces. This chapter examines the considerations annotation systems must take into account, such document structure and initial ontology, and provides an overview of current SAP implementations. The Semantic Web also results in new as well as extended applications, such as concept searching, custom web page generation, question-answering systems as well as visualization. These applications are all made possible by the semi-automatic annotation services provided by SAPs.
Delta-Like 1 Homolog (Dlk1): A Marker for Rhabdomyosarcomas Implicated in Skeletal Muscle Regeneration

Dlk1, a member of the Epidermal Growth Factor family, is expressed in multiple tissues during development, and has been detected in carcinomas and neuroendocrine tumors. Dlk1 is paternally expressed and belongs to a group of imprinted genes associated with rhabdomyosarcomas but not with other primitive childhood tumors to date. Here, we investigate the possible roles of Dlk1 in skeletal muscle tumor formation. We analyzed tumors of different mesenchymal origin for expression of Dlk1 and various myogenic markers and found that Dlk1 was present consistently in myogenic tumors. The coincident observation of Dlk1 with a highly proliferative state in myogenic tumors led us to subsequently investigate the involvement of Dlk1 in the control of the adult myogenic programme. We performed an injury study in Dlk1 transgenic mice, ectopically expressing ovine Dlk1 (membrane bound C2 variant) under control of the myosin light chain promotor, and detected an early, enhanced formation of myotubes in Dlk1 transgenic mice. We then stably transfected the mouse myoblast cell line, C2C12, with full-length Dlk1 (soluble A variant) and detected an inhibition of myotube formation, which could be reversed by adding Dlk1 antibody to the culture supernatant. These results suggest that Dlk1 is involved in controlling the myogenic programme and that the various splice forms may exert different effects. Interestingly, both in the Dlk1 transgenic mice and the DLK1-C2C12 cells, we detected reduced myostatin expression, suggesting that the effect of Dlk1 on the myogenic programme might involve the myostatin signaling pathway. In support of a relationship between Dlk1 and myostatin we detected reciprocal expression of these two transcripts during different cell cycle stages of human myoblasts. Together our results suggest that Dlk1 is a candidate marker for skeletal muscle tumors and might be involved directly in skeletal muscle tumor formation through a modulatory effect on the myogenic programme.
Biomimicry in Industry: The Philosophical and Empirical Rationale for Reimagining R&D

6 Introduction . 7 In Defense of Biomimicry . 11 Conclusion . 20 Acknowledgements . 21 III. BIOMIMICRY: A PATH TO SUSTAINABLE INNOVATION . 22 Introduction . 22 What is Biomimicry? 23 Biomimetic Design Practice . 25
Stress appraisals of UK soccer academy coaches: an interpretative phenomenological analysis

Abstract Knowledge of how sports coaches appraise stress is sparse. This study investigates coaches’ cognitive appraisals and explores the transactional nature of how coaches experience stress. Ten academy soccer coaches were interviewed using a semi-structured guide. Interpretative phenomenological analysis was employed to explore coaches’ lived experiences of stressful situations. Coaches identified a range of situational demands including performance expectations, conflicting tasks, and managing relationships. Demands were evaluated in terms of perceived psychological danger. Coaches appraised their ability to meet these demands through resources such as self-efficacy, autonomy and social support. Emotional and behavioural consequences of coaches’ cognitive appraisals were also revealed. Findings provide a deeper understanding into the specific cognitive appraisals of coaches, revealing that determinants of stress appraisals are interdependent and complex.
Menu planning by computer

less than a two-month course in the fundamentals of electronic computers and their programming. The groups from the administrations should be under dual subordination, one line to the administration and one line to the chief of the design group. : Such an organization of effort will ensure the preparation of problems that arc of actual worth to the sovnarkhoz. The first part of the design should be to agree upon a concrete list of problems that can be solved on the computer with satisfactory efficiency. This will be a type of information model for the computer center. The second part of work should be the formulation of a technical design. This will depend entirely upon the results of the applications prepared. In accordance with the characteristics of the "raw material" (e.g. the volmne of data the type of problems proposed for solution, the ! }: distribution of these throughout the course of the year), it will be necessary to choose the computer required, the (type ~ of arrangement of individual blocks, the means of conununications and the physical plant. aally, it will be necessary to study the influence of :omputation center on the work and structure of the ratus of the sowlarkhoz. It will be necessary to insure, the very beginning, a close and practical contact een these two. [d be advisable to include all of this in a concrete ional plan for carrying out the design work. should be controlled directly by the top management of the sowlarkhoz. The creation of a computer center is not an ephemeral problem that can be delegated indiscriminately; it is one of the fundamental responsibilities of the top managers of the sovnarkhoz or enterprise. At the present time, unfortunately, there is no unified plan for accomplishing the task of management automation ; and such a plan is acutely needed. It is extremely important to determine, furthermore, the particular implementors of that plan who would direct this sort of work on a statewide scale, in addition to the All-Union Institute of the Organization and Technology of Management in Minsk, it is necessary, in our opinion, to create similar institutes in a series of large economic regions. In these, design efforts should be carried out, and the institutes should have the responsibiliWv for implementing their recommendations. It would be advisable to create (more accurately to recreate) the journal, Technology of Management, for the exchange of opinion. …
Constructing and negotiating meaning : A dialogic approach to analysing chick lit.

The aims of this thesis are two-fold. This thesis seeks to critically interrogate the complex web of meaning-making practices and processes which circulate around the form of popular fiction by, about and largely for women known as chick lit. In order to address this objective, this thesis develops theoretical and analytical frameworks that are sufficiently nuanced to conceptualise and analyse the construction and negotiation of the meanings of a cultural object as dynamic, emergent, and firmly embedded in social life. Scholarly analyses of chick lit have largely been undertaken from the viewpoint of literary and cultural studies, which has resulted in a predominantly textually determined view of the genre's meanings that isolates the novels from the contexts of their production and consumption. This thesis, however, treats chick lit as a cultural phenomenon, attempting to connect a group of widely read texts with the conditions of their production, examining the way chick lit's meanings are constructed and negotiated by both the 'professional' reader in the academy and the media and the 'nonprofessional' reader in the 'everyday world', and interrogating the societal norms, beliefs and values that impact upon these appraisals. In order to conceptualise meaning-making in the complex and multifaceted way required by these aims, this thesis adopts dialogism as an interactional and contextual theory for human sense-making, and that, by placing the work of V.N. Volosinov at its centre, is linguistically oriented. However, the dialogic theoretical framework proposed in this thesis is a modified one, in that it addresses the weaknesses that arise from Volosinov's failure to adequately theorise the interrelationships between social, situated, interaction and social structure. This attempt to more adequately integrate the social into dialogism extends to the form of dialogic discourse analysis also developed in this thesis, a framework that seeks to address the limitations of current models by providing a nuanced set of tools and concepts to deal specifically with the analysis of the multiply located, multifaceted meanings that accrue to a cultural object.
Cyclovirobuxine D Inhibits Cell Proliferation and Induces Mitochondria-Mediated Apoptosis in Human Gastric Cancer Cells

Gastric cancer is one of the most common malignant cancers, with high death rates, poor prognosis and limited treatment methods. Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. In the present study, we test the effects of CVB-D on gastric cancer cells and the underlying mechanisms of action. CVB-D reduced cell viability and colony formation ability of MGC-803 and MKN28 cells in a time- and concentration-dependent manner. Flow cytometry showed that cell cycle of CVB-D treated cells was arrested at the S-phase. CVB-D also induced apoptosis in MGC-803 and MKN28 cells, especially early stage apoptosis. Furthermore, mitochondria membrane potential (Δψm) was reduced and apoptosis-related proteins, cleaved Caspase-3 and Bax/Bcl-2, were up-regulated in CVB-D-treated MGC-803 and MKN28 cells. Taken together, our studies found that CVB-D plays important roles in inhibition of gastric tumorigenesis via arresting cell cycle and inducing mitochondria-mediated apoptosis, suggesting the potential application of CVB-D in gastric cancer therapy.
Effect of feeding frequency on growth, feed utilisation and cannibalism in climbing perch Anabas testudineus (Bloch 1792) fry

A 35 days experiment was conducted to study the effect of different feeding frequencies on growth and feed utilisation in climbing perch Anabas testudineus (Bloch 1792) fry. Four different feeding frequencies in triplicate viz., 2 (T1), 3 (T2), 4 (T3) and 5 (T4) times a day were evaluated. Fry (144 nos.) of climbing perch were randomly distributed in 12 glass aquaria (50 l) containing 25 l of filtered and well aerated freshwater. Formulated pellet feed was prepared and fed @ 6% body weight to all the experimental groups at different feeding frequencies as mentioned above. At the end of the experiment, fishes were sampled to determine weight gain percentage (WG %), specific growth rate (SGR), food conversion ratio (FCR), protein efficiency ratio (PER), survival percentage (%) and partial cannibalism rate (%). Results revealed that the WG% (112.80±2.25), PER (1.65±0.03) and SGR (2.15±0.03) were significantly higher (p<0.05) in T3 group. FCR (1.55±0.03) was lowest in T3 group. Partial cannibalism rate (%) was significantly higher (p<0.05) in the treatment group T1 (6.33±0.88) whereas the survival rate (%) was lowest in T1 (91.66±4.81). The results therefore, indicated that feeding frequency of 4 times a day (T3) could be the ideal feeding frequency for better growth and feed utilisation during fry rearing of climbing perch.
Using Happiness Surveys to Value Intangibles: The Case of Airport Noise

We assess the monetary value of the noise damage, caused by aircraft noise nuisance around Amsterdam Airport, as the sum of hedonic house price differentials and a residual cost component. The residual costs are assessed from a survey, including an ordinal life satisfaction scale, on which individual respondents have scored. The derived compensation scheme depends on, among other things, the objective noise level, income, the degree to which prices account for noise differences, and the presence of noise insulation.
Retrieval-induced forgetting and judgements in impression formation

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De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation

Xist (X-inactive specific transcript) plays a crucial role in X-inactivation. This non-coding RNA becomes upregulated on the X chromosome that is to be inactivated upon differentiation. Previous studies have revealed that although maintenance-type DNA methylation is not essential for X-inactivation to occur, it is required for the stable repression of Xist in differentiated cells. However, it is unknown whether differential de novo methylation at the Xist promoter, which is mediated by Dnmt3a and/or Dnmt3b, is a cause or a consequence of monoallelic expression of Xist. We show that Xist expression is appropriately regulated in the absence of Dnmt3a and Dnmt3b and that a single X chromosome undergoes proper inactivation in mutant females. Our results indicate that a mechanism(s) other than DNA methylation plays a principal role in initiating X-inactivation. We also demonstrate that delayed upregulation of Xist does not induce X-inactivation, consistent with a crucial developmental window for the chromosomal silencing.
Populism and media policy failure

Far right populist politicians and movements have secured high levels of visibility thanks to often compliant media outlets and unregulated digital platforms. The pursuit of media coverage and the communication of rage are no longer incidental but essential to the growth of reactionary populisms. Yet, while prominent liberal media outlets are ‘aghast’ at events such as the election of Donald Trump and the Brexit vote, little attention has been paid to the structural conditions and policy frameworks that have facilitated the circulation of clickbait and misinformation, together with the incessant coverage of their leaders, that have been exploited by far right movements. This article identifies four areas of ‘media policy failure’ that have nurtured highly skewed media environments and concludes by calling for a new policy paradigm based around redistribution that aims to reconstruct media systems in order to undermine the appeal of populist forces on the far right.
Runtime System Support for Running Applications with Dynamic and Asynchronous Task Parallelism in Software DSM Systems

State-of-the-art software distributed shared-memory systems (SDSMs) provide a cost-effective solution to run single-program-multiple-data (SPMD) applications on clusters of distributed memory computers. However, SDSMs are unsuitable for running applications with dynamic, highly asynchronous task parallelism (ATP), such as graphics, simulators, and decision support systems. In ATP-based applications, the execution of tasks depends not only on the input data but also on the variable amount of data that each task produces at runtime, which generates high load imbalance and communication traffic that degrades performance of SDSM systems drastically. In this work, we propose a new load balancing (LB) mechanism to enable SDSM systems to support dynamic task scheduling as required by ATP applications. To evaluate the benefits of our LB mechanism, we developed Clik a new multithreaded SDSM system with automatic load balancing. Our preliminary performance results of Clik running on a 16-node Linux SMP cluster for five ATP applications showed that Clik attained significant speedups. For four of our five applications, the speedups varied from 7.2 up to 13.8 on 16 processors
Using the Theory of Planned Behavior to Explain Expecting Couples Birth Preparedness Intentions in a Rural Setting: A Cross-Sectional Study from Rukwa, Southern Tanzania

Background. According to the Theory of Planned Behavior, an intention to carry out a certain behavior facilitates action. In the context of planning for birth, certain preparations and planning may better ensure maternal and neonatal survival. Little is known on the predictors of birth preparedness intention among expecting couples. The aim of this study was to determine the predictors of birth preparedness intentions among expecting couples. Methods. A community based cross-sectional study targeting pregnant women and their partners was performed from June until October 2017. A three-stage probability sampling technique was employed to obtain a sample of 546 couples A structured questionnaire based upon the Theory of Planned Behavior was used. The questionnaire explored three main domains of birth preparedness intentions. These three domains included (1) attitudes towards birth preparedness, (2) perceived subjective norms towards birth preparedness, and (3) perceived behavior control towards birth preparedness. Results. The vast majority of study participants had birth preparedness intentions. This included 521 (95.4%) pregnant women and 543 (99.5%) of their male partners. After adjusting for the confounders, the predictors of birth preparedness intentions among pregnant women were attitude (AOR=70.134, 95% CI=12.536-392.360, p<0.001) and perceived behavior control (AOR=7.327, 95% CI=1.545-34.761, p<0.05) which were significant. Among male partners, only attitudes (AOR=31.315, 95% CI=1.497-655.149, p<0.05) influenced the birth preparedness intention. Conclusion. Birth preparedness intention among male partners was higher compared to their female partners. The reason for the difference could be the concern each group puts on the issue of birth preparedness. Among the three domains of intention, attitude and perceived behavior control were statistically significant predictors of birth preparedness intention among pregnant women. Attitude was the only domain which influenced birth preparedness intention among male partners. Therefore, interventional studies are recommended targeting attitudes and perceived behavior control in order to boost birth preparedness intention.
Please Scroll down for Article Journal of Human Development Undp's Gender-related Measures: Some Conceptual Problems and Possible Solutions Undp's Gender-related Measures: Some Conceptual Problems and Possible Solutions

This article may be used for research, teaching and private study purposes. Any substantial or systematic reproduction, redistribution , reselling , loan or sub-licensing, systematic supply or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this material. Abstract This paper critically reviews conceptual and empirical problems issues with the United Nations Development Programme's two gender-related indicators: the Gender-related Development Index and the Gender Empowerment Measure. While supporting the need for gender-related development measures, the paper argues that there are serious conceptual and empirical problems with both measures that limit the usefulness of these composite indicators. Where appropriate and feasible, the paper suggests modifications to the measures that address some of the identified problems.
THE EFFECTS OF ENTREPRENEURIAL ORIENTATION ON INNOVATION PERFORMANCE, OPEN INNOVATION PROCLIVITY, AND OPENNESS

This paper proposes a conceptual model of the effects of entrepreneurial orientation on innovation performance, open innovation proclivity, and organizational openness. We argue that high levels of entrepreneurial orientation increases innovation performance. Moreover, we posit that a higher degree of entrepreneurial orientation also positively affects the open innovation proclivity and the openness of a firm. The latter two constructs reinforce the suggested positive effects of entrepreneurial orientation. The article contributes to the ongoing dialog in the innovation and the entrepreneurship literatures, especially by suggesting open innovation proclivity as a missing link between the entrepreneurial orientation of a firm and its innovation performance levels.