Miracle-dz/UniFAR-FTUs huggingface dataset:
Proactive environmental management and performance by a controlling family

Purpose – This study examined how proactive environmental management affects firm performance and whether a controlling family moderates this effect. The paper aims to discuss these issues. Design/methodology/approach – The study adopted content analysis to collect data on listed Taiwanese firms and used cross-sectional regression analysis to examine the relationship between proactive environmental management and firm performance as well as the moderating role of a controlling family. Findings – The results indicated that not all types of proactive environmental management are positively associated with firm performance and that a controlling family might be more effective in low-risk proactive environmental management practices. Research limitations/implications – The focus was on the impact of proactive environmental management from the perspective of stockholders. Future research could investigate its impact on other stakeholders as well. Practical implications – The findings might convince managers th.
Can American Management Concepts Work in Russia? A Cross-Cultural Comparative Study

This article examines the main cultural differences and similarities between American managers and their Russian counterparts. It also explores the applicability of familiar American management concepts concerning leadership styles, motivation approaches, performance appraisal systems, systems for strategic planning, and organizational configurations in the context of the Russian culture. Certain American management concepts—such as legitimate power-based leadership style, employee relations policies, gainsharing, appraisals based on work team performance, strategic improvising, and strategic alliances—can be successfully put into practice in Russia. Differences in managerial values between these two countries, however, require that the application of American management approaches in Russia be carried out patiently and systematically.
Balancing revisability and robustness? A new institutionalist perspective on local government modernization

This article focuses upon one particular aspect of new institutionalist thinking – that which analyses the scope for, and constraints upon, deliberate interventions in institutional change. New institutionalist insights are used to illuminate the challenges faced by the British Labour government in its programme for modernizing local government. The focus is upon two core concepts: robustness and revisability – a pairing which highlights the potential contradictions that exist within the new institutionalist approach to design. It is argued that New Labour struggled to achieve a balance between these key design criteria during its first term, with revisability increasingly sacrificed in favour of robustness. In its second term in office (since June 2001), Labour has sought to rebalance robustness and revisability, largely through the principle of ‘earned autonomy’. In this context the values informing the institutional redesign of local government have become less clear and more contested, and there has been a progressive shift from commitment-based to control-based strategies for change.
Investor protection effects on corporate liquidity and the cost of capital

Studies by LaPorta et al. (2000, 2002) show that the strong protection of investor rights encourage the development of capital markets and are associated with higher levels of firm valuation as measured by Tobin's Q. Related research finds that well-developed capital markets produce higher rates of economic growth and allocate capital more efficiently. These studies fail, however, to explain how the investor protection environment produces higher firm values or facilitates the more efficient allocation of investment capital. Using a sample of 158 ADRs representing 26 different countries, this study provides such a linkage by examining the effect of investor protection levels on share liquidity and the firm's cost of capital. We find that lower levels of investor protection reduce share liquidity while simultaneously resulting in a higher cost of equity capital. The combination of less liquidity with a higher cost of capital suggests an explanation for the lower values observed for firms incorporated in countries with fewer investor protections.
Virulence markers in the 5' untranslated region of genotype 2 bovine viral diarrhea virus isolates.

Virulence markers to distinguish high from low virulence bovine viral diarrhea virus genotype 2 isolates have not been previously reported. The objective of this study was to identify virulence markers by evaluating the primary and secondary structures of the 5'-untranslated region of low and high virulence bovine viral diarrhea virus genotype 2 isolates. The nucleotide sequences of the entire 5'-untranslated region mRNA of eight bovine viral diarrhea virus genotype 2 isolates, four of high virulence and four of low virulence, and two genotype 1 reference isolates were determined using a polymerase chain reaction and a 5' Rapid Amplification of cDNA Ends System. Two nucleotide substitutions were identified in the internal ribosomal entry site that distinguished the high virulence from the low virulence genotype 2 isolates. The low virulence isolates had a cytosine at position 219, whereas the high virulence isolates had a uracil. At position 278, a uracil or cytosine was found in the low and high virulence groups, respectively. The substituted bases are virulence markers that were used to identify bovine viral diarrhea virus genotype 2 isolates of high virulence.
Hemodynamic changes during displacement of the beating heart using epicardial stabilization for off-pump coronary artery bypass graft surgery.

OBJECTIVE To evaluate the hemodynamic alterations during off-pump coronary artery bypass graft surgery to determine the degree of impairment caused and the techniques to rectify them. DESIGN Prospective, observational cohort study performed from January 2000 through September 2000. PARTICIPANTS Patients (n = 500) with coronary artery disease undergoing multivessel off-pump coronary artery bypass graft surgery using the Octopus tissue stabilizer (Medtronic, Inc, Minneapolis, MN). Unstable patients with ongoing ischemia were excluded from the study. INTERVENTIONS All patients were monitored with radial artery and pulmonary artery catheters and continuous transesophageal echocardiography monitoring with a multiplane transducer. The perioperative requirement of an intracoronary shunt, inotropes, or an intra-aortic balloon pump was noted. The effect of the Trendelenburg position and fluids on hemodynamics was observed. The need for defibrillation and institution of emergency cardiopulmonary bypass were major endpoints to determine the inability of the patient to tolerate displacement of the heart. MEASUREMENTS AND MAIN RESULTS Mean patient age was 59.3 +/- 11.6 years. There were 204 (40%) patients in the high-risk category; 54 (10.8%) patients had left ventricular ejection fraction <25%. The mean number of grafts was 2.7 +/- 0.8. Vertical displacement of the heart to access the lateral and inferior walls decreased the mean arterial pressure by 18 +/- 4% (p < 0.01), with a concomitant increase in central venous pressure of 66 +/- 18% (p < 0.001). The stroke volume and the cardiac index were reduced by 35.7 +/- 11% (p < 0.001) and 45 +/- 13% (p < 0.001). On transesophageal echocardiography, there was development of new regional wall motion abnormalities in 59.2% and a decrease in global left ventricular functions in 61.2%. The use of inotropes was highest during anastomosis on the posterior wall-78.4% compared with 21.9% for the anterior wall. An intra-aortic balloon pump was used in 55 (11.2%) patients, and 7 (0.71 %) patients had to be put on emergency CPB. The in-hospital mortality was 1.2%. CONCLUSION Most patients had hemodynamic changes easily correctable by fluids and inotropes. Monitoring of left ventricular and right ventricular function by transesophageal echocardiography enhances safety of the procedure and is recommended. The use of the Octopus II tissue stabilizer proved to be a safe and versatile means to stabilize the heart during off-pump coronary artery bypass procedures, especially in high-risk patients.
National study on emergency department visits for transient ischemic attack, 1992-2001.

OBJECTIVES To describe the epidemiology of U.S. emergency department (ED) visits for transient ischemic attack (TIA) and to measure rates of antiplatelet medication use, neuroimaging, and hospitalization during a ten-year time period. METHODS The authors obtained data from the 1992-2001 National Hospital Ambulatory Medical Care Survey. TIA cases were identified by having ICD-9 code 435. RESULTS From 1992 to 2001, there were 769 cases, representing 2,969,000 ED visits for TIA. The population rate of 1.1 ED visits per 1,000 U.S. population (95% CI = 0.92 to 1.30) was stable over time. TIA was diagnosed in 0.3% of all ED visits. Physicians administered aspirin and other antiplatelet agents to a small percentage of patients, and 42% of TIA patients (95% CI = 29% to 55%) received no medications at all in the ED. Too few data points existed to measure a statistically valid trend over time. Physicians performed computed tomography scanning in 56% (95% CI = 45% to 66%) of cases and performed magnetic resonance imaging (MRI) in < 5% of cases, and there was a trend toward increased imaging over time. Admission rates did not increase during the ten-year period, with 54% (95% CI = 42% to 67%) admitted. Regional differences were noted, however, with the highest admission rate found in the Northeast (68%). CONCLUSIONS Between 1992 and 2001, the population rate of ED visits for TIA was stable, as were admission rates (54%). Antiplatelet medications appear to be underutilized and to be discordant with published guidelines. Neuroimaging increased significantly. These findings may reflect the limited evidence base for the guidelines, educational deficits, or other barriers to guideline implementation.
Education, training and skills in innovation policy

The main question that guides this paper is how governments are focusing (and must focus) on competence building (education, training and skills) when designing and implementing innovation policies. After a brief literature review, this paper suggests a typology of internal/external and individual/organizational sources of competences that are related to innovation activities. This serves to examine briefly the most common initiatives that governments are taking in this regard. The paper identifies three overall deficiencies and imbalances in innovation systems in terms of education, training and skills: the insufficient levels of competences in a system, the time lag between firms’ short-term needs for specific competences and the long time required to develop them, and the imbalances between internal and external sources of competences in firms. From these, the paper elaborates a set of overall criteria for the (re)design of policy instruments addressing those tensions and imbalances.
Household Response to Government Debt: Evidence from Life Insurance Holdings

We use state‐level panel data on life insurance in force in the United States and find that a $1 increase in government debt, at either the state or federal level is associated with a $0.96 increase in the face value of the average life insurance holdings per capita for a household in the average state. This increase represents an intention to save that would almost completely offset the government debt in specific states of the world (i.e., if the insured dies). Because this state of the world is rare, the immediate increase in actual savings is only about $0.03, the cost of the additional insurance. We find, in addition, that this response occurs mainly on the intensive margin, meaning that the size of the average life insurance policy increases when government debt increases. Along the extensive margin, we find the number of policies in force falls slightly with federal debt, and rises slightly with state debt increases. The results show altruistic planning in response to changes in government debt that are consistent with Ricardian Equivalence and the long‐run neutrality of government debt.
Fibroblast growth factor‐21, body composition, and insulin resistance in pre‐pubertal and early pubertal males and females

Accumulating evidence derived primarily from animal models suggests that fibroblast growth factor‐21 (FGF‐21) may affect the musculoskeletal system via effects on the capacity of tissues to respond to insulin. A proportion of musculoskeletal properties and underpinnings of promoting/preventing insulin resistance are established early in the pubertal transition. Thus, the objective of this study was to test the hypothesis that insulin resistance and/or obesity will promote greater FGF‐21 concentration which will be inversely associated with musculoskeletal parameters [lean mass and bone mineral content (BMC)] in pre‐/early pubertal children. Given the sexual dimorphic nature of musculoskeletal development of fat mass accrual, differences by obesity status and sex were also investigated.
Pneumococcal conjugate vaccination in Canadian infants and children younger than five years of age: Recommendations and expected benefits.

INTRODUCTION Streptococcus pneumoniae infection may result in invasive pneumococcal disease (IPD), such as bacteremia, meningitis and bacteremic pneumonia, or in non-IPD, such as pneumonia, sinusitis and otitis media. In June 2001, a heptavalent pneumococcal conjugate vaccine (PCV7) (Prevnar, Wyeth Pharmaceuticals, Canada) was approved for use in children in Canada. The objective of the present paper is to review S pneumoniae-induced disease incidence and vaccine recommendations in Canadian infants and children younger than five years of age. Particular attention is given to the expected benefits of vaccination in Canada based on postmarketing data and economic modelling. METHODS Searches were performed on PubMed and Web of Science databases and specific Canadian journals using the key words 'pneumococc*', 'vaccine', 'conjugate', 'infant' and 'Canadian'. RESULTS AND DISCUSSION PCV7 appears to be safe and effective against IPD and non-IPD in children younger than five years of age and, more importantly, in children younger than two years of age (who are at highest risk for IPD). An examination of postmarketing data showed a reduction in incidence of pneumococcal disease in age groups that were vaccinated and in older age groups, indicating the likelihood of herd protection. Concurrently, there was a reduction in the occurrence of antimicrobial-resistant isolates. CONCLUSIONS The results from the present review suggest that PCV7 is currently benefiting Canadian children and society by lowering S pneumoniae-associated disease. Additional gains from herd protection and further reductions in antimicrobial resistance will be achieved as more Canadian children younger than five years of age are routinely vaccinated with PCV7.
Studies on filariasis. III. Dirofilaria immitis: emergence of infective larvae from the mouthparts of Aedes aegypti

Abstract Infective larvae of Dirofilaria immitis commonly escaped from the tips of the Iabella and rarely from the mid-portion of the labium of Aedes aegypti as they engorged blood or just probed on mice. During the infective feed a small quantity of liquid, not more than 1 µI in volume, accumulated around the emerging larvae. Liquid was never seen when uninfected mosquitoes engorged on mice. This fluid is of insect origin and probably haemolymph that exuded from the lumina of the labella or labium during worm emergence. The presence of the fluid prevents dessication of larvae on the surface of the skin and maintains them in a liquid medium until they enter the puncture wound that remains after withdrawal of the biting fascicle. The possible effects of the fluid on the geographical distribution of mosquito borne filariae are discussed.
Intellectual capital and corporate performance in Indian pharmaceutical industry

Purpose – The purpose of this paper is to study the relationship, if any, between the intellectual capital (IC) components, namely human, structural, and physical capitals with the traditional measures of performance of the company, namely profitability, productivity and market valuation.Design/methodology/approach – Value added by IC (VAIC™) for top 25 firms in the drug and pharmaceutical industry in India, for a ten‐year period from 1996 to 2006 is estimated. The evaluation is done on the basis of the ranking obtained by each firm in the VAIC index estimated. The analysis of correlation and simple linear multiple regression is done for the set of variables representing the performance of the firm and IC.Findings – The domestic firms seem to be performing well and efficiently utilizing their IC as seen by the VAIC rankings. The empirical analysis found that the human capital was the one which was seen to have the major impact on the profitability and productivity of the firms over the period of study. Th.
Foreign body reaction to calcium hydroxylapatite vocal fold augmentation.

We report a case of inflammation with foreign body cell reaction following injection of the true vocal folds (TVFs) with Radiesse (Bioform Inc, San Mateo, Calif), a synthetic calcium hydroxylapatite (CaHA) material. The patient underwent injection laryngoplasty for a 10-year history of persistent hoarseness and documented bilateral vocal fold paresis. Initial postoperative examination revealed overaugmentation with migration of the material. The material was removed in 2 successive procedures. Results of histological examination revealed the presence of chronic inflammation and foreign body giant cells (FBGCs). This is, to our knowledge, the first published case of an apparent FBGC reaction to vocal fold augmentation with Radiesse and leads us to conclude that rare CaHA rejection reactions can occur in human subjects.
Surveillance for Highly Pathogenic Avian Influenza Virus in Wild Birds during Outbreaks in Domestic Poultry, Minnesota, 2015

In 2015, a major outbreak of highly pathogenic avian influenza virus (HPAIV) infection devastated poultry facilities in Minnesota, USA. To understand the potential role of wild birds, we tested 3,139 waterfowl fecal samples and 104 sick and dead birds during March 9–June 4, 2015. HPAIV was isolated from a Cooper’s hawk but not from waterfowl fecal samples.
Pharmacokinetics of Memantine after a Single and Multiple Dose of Oral and Patch Administration in Rats

Memantine is a non‐competitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist used to treat Alzheimer's disease. We investigated memantine pharmacokinetics after oral, IV and patch administration in rats, and compared memantine pharmacokinetics after multiple‐ or single‐dose oral and transdermal administration. Venous blood was collected at preset intervals in single‐ and multiple‐dose studies. Non‐compartmental pharmacokinetics was analysed for all formulations. The oral, IV and patch memantine doses were 10 mg/kg, 2 mg/kg and 8.21 ± 0.89 mg/kg, respectively. The maximum plasma concentration was lower and the half‐life longer after patch administration than oral and IV administration. Memantine bioavailability was 41 and 63% for oral and patch administration, respectively. Steady state was achieved around 24 hr for oral and patch administration. The mean AUC increased after oral or patch administration from single to multiple dose. The memantine patch formulation displayed a longer duration of action and lower peak plasma concentration. However, drug exposure was similar to the oral formulation at each dose. Additionally, the memantine patch formulation displayed a smaller interindividual variability and lower accumulation than the oral formulation.
‘Changing Before Our Very Eyes’: Agrarian Questions and the Politics of Land in Capitalism Today

This paper endorses the criticisms of neo-classical populism and its advocacy of redistributive land reform provided by other contributions to this special issue of the Journal, to which it adds several further points. If GKI propose a version of an agrarian question of ‘small’ or ‘family’ farming, and its resolution through a familiar (Chayanovian) path of development, much of the critique rests, in one way or another, on the ‘classic’ agrarian question in capitalist transition, in effect the agrarian question of capital in which the agrarian question of labour was once subsumed. Here the question is posed whether, in the conditions of contemporary ‘globalization’ and its tendency to the ‘fragmentation’ of labour, there might be a new agrarian question of labour, now detached from that of capital, and which generates a new politics of struggles over land (and its distribution). Even to conceive of this question is beyond the analytical and political field of vision of neo-classical populism. Some of the dimensions of an agrarian question of labour are illustrated in a brief consideration of recent, and highly contradictory, events in Zimbabwe: a unique case of comprehensive, regime-sanctioned, confiscatory land redistribution in the world today.
The Political Economy of Health Reform: Turkey's Health Transformation Program, 2003-2012

This dissertation explores the political economy of Turkey’s large-scale health systems reform, known as the Health Transformation Program (HTP) (2003 – 2012). It does this by analyzing the role of institutions, physicians, and patients in the Ministry of Health’s efforts to adopt and implement changes to the country’s health financing, health workforce, and primary care systems. In the first chapter, I present a qualitative case study that uses primary interview data to explain how Turkey adopted a universal and unified health coverage system between 2003 and 2008. By applying Immergut’s institutional veto points theory, I show Minister of Health Akdag (2002-2013) and his team of advisors used targeted strategies to overcome obstacles at critical veto points blocking adoption. This analysis fills an important gap in the literature on universal health coverage by providing a theory-based explanation for how a reform can be accomplished. The second paper then looks at how Minister Akdag overcame opposition from an organized physician group, the Turkish Medical Association (TMA), to adopt legislation that banned physician dual practice. This analysis contributes to the literature on the role of physicians in health reform by presenting a case study where an organized physicians association was not able to act exert veto power to block policy adoption. Rather, I argue that Minister Akdag used a divide and then conquer political strategy, where he acted to exploit coordination problems among physicians by appealing to their individual interests and undermining the authority of TMA and its base of university physicians, to create a favorable political environment to ban dual practice and strengthen service delivery capacity. The fourth chapter considers how the HTP affected public opinion of Turkey’s reformed primary health care system, known as the Family Medicine System. I take advantage of the staged-rolled out of the Family Medicine System at the provincial level to estimate its effect on patient satisfaction using provincially-representative patient exit survey data from 2010, 2011 and 2012. This study provides some of the first national level evidence that primary health care reform underpinned by the FM system can effectively improve patient satisfaction - a health system goal. The final chapter summarizes the main results of Chapters 2, 3, and 4, discusses their limitations, and presents policy implications that can be derived from this research.