Miracle-dz/UniFAR-FTUs huggingface dataset:
The Optical and Near-Infrared Properties of Galaxies. I. Luminosity and Stellar Mass Functions

We use a large sample of galaxies from the Two Micron All Sky Survey (2MASS) and the Sloan Digital Sky Survey (SDSS) to calculate galaxy luminosity and stellar mass functions in the local universe. We estimate corrections for passband shifting and galaxy evolution, as well as present-day stellar mass-to-light (M/L) ratios, by fitting the optical-near-infrared galaxy data with simple models. Accounting for the 8% galaxy overdensity in the SDSS early data release region, the optical and near-infrared luminosity functions we construct for this sample agree with most recent literature optical and near-infrared determinations within the uncertainties. We argue that 2MASS is biased against low surface brightness galaxies and use SDSS plus our knowledge of stellar populations to estimate the "true" K-band luminosity function. This has a steeper faint end slope and a slightly higher overall luminosity density than the direct estimate. Furthermore, assuming a universally applicable stellar initial mass function (IMF), we find good agreement between the stellar mass function we derive from the 2MASS/SDSS data and that derived by Cole et al. The faint end slope for the stellar mass function is steeper than -1.1, reflecting the low stellar M/L ratios characteristic of low-mass galaxies. We estimate an upper limit to the stellar mass density in the local universe Ω*h = 2.0 ± 0.6 × 10-3 by assuming an IMF as rich in low-mass stars as allowed by observations of galaxy dynamics in the local universe. The stellar mass density may be lower than this value if a different IMF with fewer low-mass stars is assumed. Finally, we examine type-dependence in the optical and near-infrared luminosity functions and the stellar mass function. In agreement with previous work, we find that the characteristic luminosity or mass of early-type galaxies is larger than for later types, and the faint end slope is steeper for later types than for earlier types. Accounting for typing uncertainties, we estimate that at least half, and perhaps as much as 3/4, of the stellar mass in the universe is in early-type galaxies. As an aid to workers in the field, we present in an Appendix the relationship between model stellar M/L ratios and colors in SDSS/2MASS passbands, an updated discussion of near-infrared stellar M/L ratio estimates, and the volume-corrected distribution of g- and K-band stellar M/L ratios as a function of stellar mass.
What Trust Means in E-Commerce Customer Relationships: An Interdisciplinary Conceptual Typology

Trust is a vital relationship concept that needs clarification because researchers across disciplines have defined it in so many different ways. A typology of trust types would make it easier to compare and communicate results, and would be especially valuable if the types of trust related to one other. The typology should be interdisciplinary because many disciplines research e-commerce. This paper justifies a parsimonious interdisciplinary typology and relates trust constructs to e-commerce consumer actions, defining both conceptual-level and operational-level trust constructs. Conceptual-level constructs consist of disposition to trust (primarily from psychology), institution-based trust (from sociology), and trusting beliefs and trusting intentions (primarily from social psychology). Each construct is decomposed into measurable subconstructs, and the typology shows how trust constructs relate to already existing Internet relationship constructs. The effects of Web vendor interventions on consumer behaviors are posited to be partially mediated by consumer trusting beliefs and trusting intentions in the e-vendor.
Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer

Lung cancer or pulmonary carcinoma is primarily derived from epithelial cells that are thin and line on the alveolar surfaces of the lung for gas exchange. ANO1/TMEM16A, initially identified from airway epithelial cells, is a member of Ca2+-activated Cl- channels (CaCCs) that function to regulate epithelial secretion and cell volume for maintenance of ion and tissue homeostasis. ANO1/TMEM16A has recently been shown to be highly expressed in several epithelium originated carcinomas. However, the role of ANO1 in lung cancer remains unknown. In this study, we show that inhibition of calcium-activated chloride channel ANO1/TMEM16A suppresses tumor growth and invasion in human lung cancer. ANO1 is upregulated in different human lung cancer cell lines. Knocking-down ANO1 by small hairpin RNAs inhibited proliferation, migration and invasion of GLC82 and NCI-H520 cancel cells evaluated by CCK-8, would-healing, transwell and 3D soft agar assays. ANO1 protein is overexpressed in 77.3% cases of human lung adenocarcinoma tissues detected by immunohistochemistry. Furthermore, the tumor growth in nude mice implanted with GLC82 cells was significantly suppressed by ANO1 silencing. Taken together, our findings provide evidence that ANO1 overexpression contributes to tumor growth and invasion of lung cancer; and suppressing ANO1 overexpression may have therapeutic potential in lung cancer therapy.
Acute Myocardial Infarction in a Young Man; Fatal Blow of the Marijuana: A Case Report

Marijuana is known to have been used for medicinal and recreational purposes for thousands of years. Although marijuana has some diverse effects on cardiovascular system, there is insufficient knowledge concerning acute myocardial infarction (AMI) associated with marijuana and its underlying mechanism. We report the case of a 26 year-old young man suffering from ST-elevated AMI caused by marijuana abuse, which was successfully treating with percutaneous coronary intervention. It should be kept in mind that marijuana could be one of the most probable causes of AMI observed in apparently healthy young persons who use this drug.
Regulation of human neural precursor cells by laminin and integrins

Deciphering the factors that regulate human neural stem cells will greatly aid in their use as models of development and as therapeutic agents. The extracellular matrix (ECM) is a component of stem cell niches in vivo and regulates multiple functions in diverse cell types, yet little is known about its effects on human neural stem/precursor cells (NSPCs). We therefore plated human NSPCs on four different substrates (poly‐L‐ornithine, fibronectin, laminin, and matrigel) and compared their responses with those of mouse NSPCs. Compared with the other substrates, laminin matrices enhanced NSPC migration, expansion, differentiation into neurons and astrocytes, and elongation of neurites from NSPC‐derived neurons. Laminin had a similar spectrum of effects on both human and mouse cells, highlighting the evolutionary conservation of NSPC regulation by this component of the ECM. Flow cytometry revealed that human NSPCs express on their cell surfaces the laminin‐binding integrins α3, α6, α7, β1, and β4, and function‐blocking antibodies to the α6 subunit confirmed a role for integrins in laminin‐dependent migration of human NSPCs. These results define laminin and its integrin receptors as key regulators of human NSPCs. © 2006 Wiley‐Liss, Inc.
Polycyclic Aromatic Hydrocarbons in Nigerian Oil-based Drill-cuttings： Evidence of Petrogenic and Pyrogenic Effects

Compositional distribution and sources of polycyclic aromatic hydrocarbons (PAHs) in Nigerian oil-based drill-cuttings have been studied for evidence of petrogenic and/or pyrogenic effects with recommendations for the strict enforcement of the ban on the use of oil-based mud in drilling by government regulatory agencies and prior bio-treatment of the drill cuttings before final fate. Laboratory analysis of the drill cuttings with a Gas Chromatogram Model 6890N equipped with a flame ionization detector showed that the total initial PAHs concentration of the drill-cuttings was 223.52mg/kg while the initial individual PAHs concentrations ranged from 1.67 to 70.7 mg/kg, dry weight, with a 90% predominance of the combustion-specific 3-ring PAHs. The ratio of anthracene to (phenanthrene + anthracene) = 0.31 was found to be greater than the 0.10 pyrogenic source-criterion for PAHs fraction of molar-mass 178g/mol while the ratio of fluoranthene to (pyrene + fluoranthene) = 0.40 was found to be less than the 0.50 petrogenic source-criterion for fraction of molar-mass 202g/mol suggesting that the PAHs were from pyrogenic and petrogenic sources. Pyrogenic PAHs might be from a possible local heat effect while petrogenic PAHs might be from anthropogenic petroleum fractions in proprietary oil-based mud used in drilling. Consequently, the drill cuttings were composted by homogenizing 4000g of the drill cuttings, 920g of top-soil and 154g of saw dust and poultry droppings in a 10-litre plastic container of very low thermal conductivity in the ratio of 26:6:1. Mixing and watering of the reactors were done at 3 days interval under ambient temperature of 30°C for 42 days. After the bioremediation exercise, the total PAHs remaining in the drill cuttings were 4.25mg/kg (representing a 98.1% reduction). The half-lives of the PAHs in the medium ranged from 8 to 43 days.
Fibroblast heterogeneity: more than skin deep

Dermal fibroblasts are a dynamic and diverse population of cells whose functions in skin in many respects remain unknown. Normal adult human skin contains at least three distinct subpopulations of fibroblasts, which occupy unique niches in the dermis. Fibroblasts from each of these niches exhibit distinctive differences when cultured separately. Specific differences in fibroblast physiology are evident in papillary dermal fibroblasts, which reside in the superficial dermis, and reticular fibroblasts, which reside in the deep dermis. Both of these subpopulations of fibroblasts differ from the fibroblasts that are associated with hair follicles. Fibroblasts engage in fibroblast-epidermal interactions during hair development and in interfollicular regions of skin. They also play an important role in cutaneous wound repair and an ever-increasing role in bioengineering of skin. Bioengineered skin currently performs important roles in providing (1) a basic understanding of skin biology, (2) a vehicle for testing topically applied products and (3) a resource for skin replacement.
The role of carers in supporting the progress of care leavers in the world of work

The aim of this component of a preliminary cross-national study (Ireland and Catalonia) of care leavers' experience in the world of work is to explore how carers may influence the entry of young people in care into the world of work and how they may also influence the young people's progress in that world. A total of 22 care leavers, aged 23–33 years, were recruited on the basis of their having substantial employment experience since leaving care. Evidence from the interviews reveals the importance of the role of carers in the work-related progression of the young care leavers, especially in relation to gaining work experience while they were still in care. The qualitative analysis shows that carers were influential in promoting (and sometimes hindering) progress in work and education. Carers were often reported to play an important role in opening up opportunities, giving support (modelling skill development, giving practical help, etc.), being role models and cultivating the young person's agency. On the basis of these findings, we propose an initial conceptualization of carer roles in positive work support.
Brain Volume Changes After Withdrawal of Atypical Antipsychotics in Patients With First-Episode Schizophrenia

The influence of antipsychotic medication on brain morphology in schizophrenia may confound interpretation of brain changes over time. We aimed to assess the effect of discontinuation of atypical antipsychotic medication on change in brain volume in patients. Sixteen remitted, stable patients with first-episode schizophrenia, schizoaffective or schizophreniform disorder and 20 healthy controls were included. Two magnetic resonance imaging brain scans were obtained from all subjects with a 1-year interval. The patients either discontinued (n = 8) their atypical antipsychotic medication (olanzapine, risperidone, or quetiapine) or did not (n = 8) discontinue during the follow-up period. Intracranial volume and volumes of total brain, cerebral gray and white matter, cerebellum, third and lateral ventricle, nucleus caudatus, nucleus accumbens, and putamen were obtained. Multiple linear regression analyses were used to assess main effects for group (patient-control) and discontinuation (yes-no) for brain volume (change) while correcting for age, sex, and intracranial volume. Decrease in cerebral gray matter and caudate nucleus volume over time was significantly more pronounced in patients relative to controls. Our data suggest decreases in the nucleus accumbens and putamen volumes during the interval in patients who discontinued antipsychotic medication, whereas increases were found in patients who continued their antipsychotics. We confirmed earlier findings of excessive gray matter volume decrements in patients with schizophrenia compared with normal controls. We found evidence suggestive of decreasing volumes of the putamen and nucleus accumbens over time after discontinuation of medication. This might suggest that discontinuation reverses effects of atypical medication.
Managing brands and customer engagement in online brand communities

Purpose – Given the dramatic technology‐led changes that continue to take place in the marketplace, researchers and practitioners alike are keen to understand the emergence and implications of online brand communities (OBCs). The purpose of this paper is to explore OBCs from both consumer and company perspectives.Design/methodology/approach – The study provides a synthesis of the extant OBC literature to further our understanding of OBCs, and also puts forth future priorities for OBC research.Findings – A conceptual framework is provided that extends our understanding of OBCs and consumer engagement. Four key OBC dimensions (brand orientation, internet‐use, funding and governance) are identified and three antecedents (brand‐related, social and functional) are proposed of consumer‐OBC engagement.Originality/value – This study is the first to explore key dimensions of OBCs, and the differing but related perspectives of the consumers and organizations involved.
An evaluation of keyword extraction from online communication for the characterisation of social relations

The set of interpersonal relationships on a social network service or a similar online community is usually highly heterogenous. The concept of tie strength captures only one aspect of this heterogeneity. Since the unstructured text content of online communication artefacts is a salient source of information about a social relationship, we investigate the utility of keywords extracted from the message body as a representation of the relationship's characteristics as reflected by the conversation topics. Keyword extraction is performed using standard natural language processing methods. Communication data and human assessments of the extracted keywords are obtained from Facebook users via a custom application. The overall positive quality assessment provides evidence that the keywords indeed convey relevant information about the relationship.
A new theoretical modeling for the Nyquist pulses processing used widely over communication channels for systems with high transmission rates

This paper presents an innovative theoretic and numerical approach for modeling the classic pulse introduce by Nyquist, which is a very important a digital modulation that one of the main stakes of the area of digital signal processing. An appropriate revision over concept of Operational Window Aperture with the purpose to check our approach by applying it over the Raised Cosine pulse, and as a direct consequence will permit to reach our final objective. A complementary revision will be made over the new concept of a digital modulation introduced by the authors previously which was defined as the Rise Time Modulation (RTM) since part of this technological approach will be concerned in this paper. The technique adopted for modeling both full and half pulses can be applied for a wide class of digital transmission systems which demand an appropriate modeling for all communication channels. Some considerations will be performed to present a Nyquist pulse with distinct two roll off factors, that can results the optimization of the interference as well as the intrinsic noises that appear in those systems with a very high transmission rates.
Human Motor Corpus Callosum: Topography, Somatotopy, and Link between Microstructure and Function

The corpus callosum (CC) is the principal white matter fiber bundle connecting neocortical areas of the two hemispheres. Although an object of extensive research, important details about the anatomical and functional organization of the human CC are still largely unknown. Here we focused on the callosal motor fibers (CMFs) that connect the primary motor cortices (M1) of the two hemispheres. Topography and somatotopy of CMFs were explored by using a combined functional magnetic resonance imaging/diffusion tensor imaging fiber-tracking procedure. CMF microstructure was assessed by fractional anisotropy (FA), and CMF functional connectivity between the hand areas of M1 was measured by interhemispheric inhibition using paired-pulse transcranial magnetic stimulation. CMFs mapped onto the posterior body and isthmus of the CC, with hand CMFs running significantly more anteriorly and ventrally than foot CMFs. FA of the hand CMFs but not FA of the foot CMFs correlated linearly with interhemispheric inhibition between the M1 hand areas. Findings demonstrate that CMFs connecting defined body representations of M1 map onto a circumscribed region in the CC in a somatotopically organized manner. The significant and topographically specific positive correlation between FA and interhemispheric inhibition strongly suggests that microstructure can be directly linked to functional connectivity. This provides a novel way of exploring human brain function that may allow prediction of functional connectivity from variability of microstructure in healthy individuals, and potentially, abnormality of functional connectivity in neurological or psychiatric patients.
Convergence of Adaptive Sampling Schemes

In the design of ecient simulation algorithms, one is often beset with a poor choice of proposal distributions. Although the performances of a given kernel can clarify how adequate it is for the problem at hand, a permanent on-line modification of kernels causes concerns about the validity of the resulting algorithm. While the issue is quite complex and most often intractable for MCMC algorithms, the equivalent version for importance sampling algorithms can be validated quite precisely. We derive sucient convergence conditions for a wide class of population Monte Carlo algorithms and show that Rao‐ Blackwellized versions asymptotically achieve an optimum in terms of a Kullback divergence criterion, while more rudimentary versions simply do not benefit from repeated updating.
A hardware immune system for benchmark state machine error detection

A novel error detection mechanism is demonstrated for integration into a hardware fault tolerant system. Inspiration is taken from principles of immunology to create a hardware immune system that runs in real-time hardware and continuously monitors a finite state machine architecture for errors. The work is demonstrated through immunisation of the ISCAS'89 benchmark state machine data set.
Distinct patterns of grey matter abnormality in high-functioning autism and Asperger's syndrome.

BACKGROUND Autism exists across a wide spectrum and there is considerable debate as to whether children with Asperger's syndrome, who have normal language milestones, should be considered to comprise a subgroup distinct other from high-functioning children with autism (HFA), who have a history of delayed language development. Magnetic resonance imaging (MRI) studies of autism are in disagreement. One possible reason is that the diagnosis of autism takes precedence over Asperger's syndrome and a distinction in language acquisition is rarely made. We therefore planned to examine a whole brain hypothesis that the patterns of grey matter differences in Asperger's syndrome and HFA can be distinguished. METHODS We used voxel-based computational morphometry to map grey matter volume differences in 33 children with either Asperger's syndrome or high-functioning autism compared to 55 typical developing control children balanced for age, IQ, gender, maternal language and ethnicity. RESULTS Children with HFA had significantly smaller grey matter volumes in subcortical, posterior cingulate and precuneus regions than the Asperger's group. Compared to controls, children with HFA had smaller grey matter volumes in predominantly fronto-pallidal regions, while children with Asperger's had less grey matter in mainly bilateral caudate and left thalamus. In addition we found a significant negative correlation between the size of a grey matter cluster around BA44 language area and the age of acquisition of phrase speech in the children with HFA. When the groups were combined we confirmed a mixed picture of smaller grey matter volumes in frontal, basal ganglia, temporal and parietal regions. CONCLUSIONS Our study suggests that the underlying neurobiology in HFA and Asperger's syndrome is at least partly discrete. Future studies should therefore consider the history of language acquisition as a valuable tool to refine investigation of aetiological factors and management options in pervasive developmental disorders.
Faraday rotation as a diagnostic of Galactic foreground contamination of cosmic microwave background maps

We present a diagnostic test of possible Galactic contamination of cosmic microwave background (CMB) sky maps designed to provide an independent check on the methods used to compile these maps. The method involves a non-parametric measurement of cross-correlation between the Faraday rotation measure (RM) of extragalactic sources and the measured microwave signal at the same angular position. We argue that statistical properties of the observed distribution of rotation measures are consistent with a Galactic origin, an argument reinforced by a direct measurement of cross-correlation between the dust, free-free and synchrotron foreground maps and the RM values, with the strongest correlation being for dust and free-free. We do not find any statistically compelling evidence for correlations between the RM values and the COBE Differential Microwave Radiometer (DMR) maps at any frequency, so there is no evidence of residual contamination in these CMB maps. On the other hand, there is a statistically significant correlation of RM with the preliminary Wilkinson Microwave Anisotropy Probe (WMAP) individual frequency maps which remains significant in the Tegmark et al. Wiener-filtered map, but not in the internal linear combination map produced by the WMAP team.