Miracle-dz/UniFAR-FTUs huggingface dataset:
Insight in Relation to Psychosocial Adjustment in Schizophrenia

Insight impairment occurs commonly in patients with schizophrenia, and it can be expected that patients with impaired insight may subsequently have poorer psychosocial adjustment. The aim of the present study was to measure the relationship between insight and psychosocial adjustment in 38 inpatients with a diagnosis of DSM-IV schizophrenia. Insight was assessed using the Scale to Assess Unawareness of Mental Disorder. A comprehensive set of measures was used to assess psychosocial adjustment. No relationship was found between measures of psychosocial adjustment and insight. However, a self-rated measure of psychosocial adjustment was partially related to insight. Our results suggest that patients’ insight levels may not be reliable predictors of the patients’ level of psychosocial adjustment, and that these findings may need to be considered in continuous care of psychotic patients, in particular when outpatient care needs to be planned.
Research Paper: The Evaluation of a Pulmonary Display to Detect Adverse Respiratory Events Using High Resolution Human Simulator

OBJECTIVE Authors developed a picture-graphics display for pulmonary function to present typical respiratory data used in perioperative and intensive care environments. The display utilizes color, shape and emergent alerting to highlight abnormal pulmonary physiology. The display serves as an adjunct to traditional operating room displays and monitors. DESIGN To evaluate the prototype, nineteen clinician volunteers each managed four adverse respiratory events and one normal event using a high-resolution patient simulator which included the new displays (intervention subjects) and traditional displays (control subjects). Between-group comparisons included (i) time to diagnosis and treatment for each adverse respiratory event; (ii) the number of unnecessary treatments during the normal scenario; and (iii) self-reported workload estimates while managing study events. MEASUREMENTS Two expert anesthesiologists reviewed video-taped transcriptions of the volunteers to determine time to treat and time to diagnosis. Time values were then compared between groups using a Mann-Whitney-U Test. Estimated workload for both groups was assessed using the NASA-TLX and compared between groups using an ANOVA. P-values < 0.05 were considered significant. RESULTS Clinician volunteers detected and treated obstructed endotracheal tubes and intrinsic PEEP problems faster with graphical rather than conventional displays (p < 0.05). During the normal scenario simulation, 3 clinicians using the graphical display, and 5 clinicians using the conventional display gave unnecessary treatments. Clinician-volunteers reported significantly lower subjective workloads using the graphical display for the obstructed endotracheal tube scenario (p < 0.001) and the intrinsic PEEP scenario (p < 0.03). CONCLUSION Authors conclude that the graphical pulmonary display may serve as a useful adjunct to traditional displays in identifying adverse respiratory events.
User-controllable polycube map for manifold spline construction

Polycube T-spline has been formulated elegantly that can unify T-splines and manifold splines to define a new class of shape representations for surfaces of arbitrary topology by using polycube map as its parametric domain. In essense, The data fitting quality using polycube T-splines hinges upon the construction of underlying polycube maps. Yet, existing methods for polycube map construction exhibit some disadvantages. For example, existing approaches for polycube map construction either require projection of points from a 3D surface to its polycube approximation, which is therefore very difficult to handle the cases when two shapes differ significantly; or compute the map by conformally deforming the surfaces and polycubes to the common canonical domain and then construct the map using function composition, which is challenging to control the location of singularities and makes it hard for the data-fitting and hole-filling processes later on. This paper proposes a novel framework of user-controllable polycube maps, which can overcome disadvantages of the conventional methods and is much more efficient and accurate. The current approach allows users to directly select the corner points of the polycubes on the original 3D surfaces, then construct the polycube maps by using the new computational tool of discrete Euclidean Ricci flow. We develop algorithms for computing such polycube maps, and show that the resulting user-controllable polycube map serves as an ideal parametric domain for constructing spline surfaces and other applications. The location of singularities can be interactively placed where no important geometric features exist. Experimental results demonstrate that the proposed polycube maps introduce lower area distortion and retain small angle distortion as well, and subsequently make the entire hole-filling process much easier to accomplish.
Congenital mesoblastic nephroma: Clinical analysis of eight cases and a review of the literature

Congenital mesoblastic nephroma (CMN) is a mesenchymal renal tumor. The aim of the present study was to review the clinical characteristics and outcome of CMN in infants. A retrospective file review was conducted of eight cases of CMN treated at the Children’s Hospital of Fudan University between 2004 and 2012. Ultrasound and computerized tomography scans had been performed on all eight patients. Two cases presented with a solid tumor and exhibited pathological features consistent with those of classic CMN, five cases exhibited cystic, hemorrhagic and necrotic characteristics, with calcification and pathology consistent with the cellular variant of CMN and one case presented with a solid tumor, which exhibited pathological features consistent with ceullular CMN. Histology confirmed classic CMN in two patients and cellular CMN in six patients. For surgical intervention, four cases had radical nephrectomy, one case had a half nephrectomy and three cases had tumor enucleation performed. Two cases had received pre-operative chemotherapy, but exhibited no response, and three cases received post-operative chemotherapy. Two patients were lost to follow-up, but the remaining six patients survived to the end of follow-up without further complications. The mean follow-up time was 24.6 months. In conclusion, the differential diagnosis between CMN and Wilms’ tumor is critical. Imaging characteristics are partially correlated with pathological characteristics. Surgery is the main treatment for CMN, but pre-operative chemotherapy is not particularly effective. The efficacy of post-operative chemotherapy requires further investigation, but the prognosis is positive.
Accountability and Flexibility in Public Schools: Evidence from Boston's Charters and Pilots

Charter schools are publicly funded but operate outside the regulatory framework and collective bargaining agreements characteristic of traditional public schools. In return for this freedom, charter schools are subject to heightened accountability. This paper estimates the impact of charter school attendance on student achievement using data from Boston, where charter schools enroll a growing share of students. We also evaluate an alternative to the charter model, Boston's pilot schools. These schools have some of the independence of charter schools, but operate within the school district, face little risk of closure, and are covered by many of same collective bargaining provisions as traditional public schools. Estimates using student assignment lotteries show large and significant test score gains for charter lottery winners in middle and high school. In contrast, lottery-based estimates for pilot schools are small and mostly insignificant. The large positive lottery-based estimates for charter schools are similar to estimates constructed using statistical controls in the same sample, but larger than those using statistical controls in a wider sample of schools. The latter are still substantial, however. The estimates for pilot schools are smaller and more variable than those for charters, with some significant negative effects.
Distributed Volt/VAr Control by PV Inverters

A major technical obstacle for rooftop photovoltaics (PV) integration into existing distribution systems is the voltage rise due to the reverse power flow from the distributed PV sources. This paper describes the implementation of a voltage control loop within PV inverters that maintains the voltage within acceptable bounds by absorbing or supplying reactive power. In principle, this can be considered to be a form of distributed Volt/VAr control, which is conventionally performed by coordinated control of capacitor banks and transformer tap changers. Comprehensive simulation studies on detailed feeder models are used to demonstrate that the proposed control scheme will mitigate voltage rises.
Complex hand operation recognition method using salient features of EEG

The purpose of the research is to discriminate different human hand operations which is a helpful tool for real time control of robotic hand. In this paper, the salient features (amplitude, mean, median, maximum frequency, delta value) of EEG signal are extracted utilizing spectral analysis methods such as Statistical, Fourier and Wavelet analysis. And on the basis of SVM algorithm, the overall recognition rate found for statistical and DFT analysis is 85.1% and 77% respectively while the figure is 98.6% for DWT analysis. The results show that our proposed method provides highly improved performance than the traditional ones.
Different cis-Acting Elements Are Involved in the Regulation of TRP1 and TRP2 Promoter Activities by Cyclic AMP: Pivotal Role of M Boxes (GTCATGTGCT) and of Microphthalmia

ABSTRACT In melanocytes and in melanoma cells, cyclic AMP (cAMP)-elevating agents stimulate melanogenesis and increase the transcription of tyrosinase, the rate-limiting enzyme in melanin synthesis. However, two other enzymes, tyrosinase-related protein 1 (TRP1) and TRP2, are required for a normal melanization process leading to eumelanin synthesis. In B16 melanoma cells, we demonstrated that stimulation of melanogenesis by cAMP-elevating agents results in an increase in tyrosinase, TRP1, and TRP2 expression. cAMP, through a cAMP-dependent protein kinase pathway, stimulates TRP1 and TRP2 promoter activities in both B16 mouse melanoma cells and normal human melanocytes. Regulation of the TRP1 and TRP2 promoters by cAMP involves a M box and an E box. Further, a classical cAMP response element-like motif participates in the cAMP responsiveness of the TRP2 promoter, demonstrating that the TRP2 gene is subjected to different regulatory processes, which could account for its different expression patterns during embryonic development or under specific physiological and pathological conditions. We also found that microphthalmia, a basic helix-loop-helix transcription factor, strongly stimulates the transcriptional activities of the TRP1 and TRP2 promoters, mainly through binding to the M boxes. Additionally, we demonstrated that cAMP increases microphthalmia expression and thereby its binding to TRP1 and TRP2 M boxes. These convergent and compelling results disclose at least a part of the molecular mechanism involved in the regulation of melanogenic gene expression by cAMP and emphasize the pivotal role of microphthalmia in this process.
SEDUCTIONS OF METHOD: REJOINDER TO NAGIN AND TREMBLAY'S "DEVELOPMENTAL TRAJECTORY GROUPS: FACT OR FICTION?"

Remember LISREL? Many of us can recall a time when papers were accepted (or rejected) in peer-reviewed journals based on the choice of this then-preferred method. Alas, criminology has witnessed a recurring sequence of hegemonic statistical methods. Before LISREL came path analysis and before that factor analysis was all the rage; in the 1980s event history analysis ruled for a brief stint and since the 1990s HLM has come on strong. It is even common to read in abstracts nowadays that a paper applies (fill in the acronym for method) as if that were a contribution in itself. We might include as well the criminal career paradigm that reigned for years largely on grounds of method (for example, how best to measure lambda). Enter group-based trajectory modeling, aka TRAJ, self-described by Nagin and Tremblay (2005: 874) as the current “statistical method of choice” for developmental research. In a remarkably short time by academic standards, more than fifty papers have been published using group-based modeling, and many more are surely in the pipeline. Is TRAJ just another statistical fad that will pass or has it transformed our knowledge and the way we conduct research?
Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme.

The synthesis of T2 bacteriophage deoxyribonucleic acid is now known to depend on the development of a series of new enzymes which are undetectable in uninfected Escherichia coli (2-7). An augmented rate of deoxyribonucleic acid synthesis also occurs (8) which is accompanied by an approximately lo-fold increase in polymerase activity in extracts of these cells, as compared with extracts of uninfected cells (3). In order to observe this increase in polymerase activity, it was essential to assay the enzyme with a heated deoxyribonucleic acid primer ; the requirement for a heated primer is not demonstrable for the polymerase activity in extracts of uninfected cells. An important question regarding the augmented polymerase level was whether it was due to the increased production of the pre-existing E. coli polymerase or to the synthesis of a totally new phagedirected enzyme. Koerner, Smith, and Buchanan (6) have also considered this question. Although it could have been assumed that there was an increase in production of the host polymerase rather than the introduction of information for the synthesis of a totally new enzyme, several facts argued against this. First, there was the novel requirement for a heated deoxyribonucleic acid primer in order to observe the increased polymerase levels (3). Secondly, there was the observation of Bessman and Van Bibber (9) that the loto 20-fold elevated level of deoxyguanylate kinase in phage-infected cells does not show the potassium requirement demonstrated for the kinase of the uninfected cells. Finally, it appears that host cell protein synthesis ceases upon infection (lo-12), and there is no mechanism at hand to explain how the invading phage deoxyribonucleic acid selects the production, and at an augmented level, of certain kinases and polymerase of the many hundreds of proteins normally produced by the host cell. Bello, Van Bibber, and Bessman (13) have now shown that the deoxyguanylate kinase of infected cells is physically distinct and separable from the host cell enzyme, and we have made a similar observation for the polymerase. The present report describes the purification and properties of the new polymerase of T2-infected Escherichiu co&i (T2 polymerase) and demonstrates by several diierent criteria that the polymerase of uninfected E. coli (E. coli polymerase) and the T2 polymerase are distinct and different enzymes.
Multigenerational Living Arrangements among Migrants # 366

There is a signifi cantly higher prevalence of multigenerational living arrangements among migrants than among natives in Germany which may be explained with migrants choosing this household structure in order to compensate for economic disadvantages. This hypothesis is tested by analyzing the economic conditions within multigenerational households. The results show that in multigenerational migrant households, more groups contribute signifi cantly to the household income than in comparable native households – in particular in households below the at-risk-of-poverty line. On the individual level, the results reveal that migrant children in multigenerational households have lower labor force participation rates than native children or migrant children in other household types. Therefore, this study provides evidence for a correlation between multigenerational cohabitation and economic conditions among migrants. JEL Classifi cation: F22, J12, J20, J30
Lebesgue constants in polynomial interpolation

Lagrange interpolation is a classical method for approximating a continuous function by a polynomial that agrees with the function at a number of chosen points (the “nodes”). However, the accuracy of the approximation is greatly influenced by the location of these nodes. Now, a useful way to measure a given set of nodes to determine whether its Lagrange polynomials are likely to provide good approximations is by means of the Lebesgue constant. In this paper a brief survey of methods and results for the calculation of Lebesgue constants for some particular node systems is presented. These ideas are then discussed in the context of Hermite–Fejer interpolation and a weighted interpolation method where the nodes are zeros of Chebyshev polynomials of the second kind.
Direct measurement of spatial modes of a microcantilever from thermal noise

Measurements of the deflection induced by thermal noise have been performed on a rectangular atomic force microscope cantilever in air. The detection method, based on polarization interferometry, can achieve a resolution of 10−14 m/Hz in the frequency range 1–800 kHz. The focused beam from the interferometer probes the cantilever at different positions along its length, and the spatial modes’ shapes are determined up to the fourth resonance, without external excitation. Results are in good agreement with theoretically expected behavior. From this analysis accurate determination of the elastic constant of the cantilever is also achieved.
Lipopolysaccharide Modifies Glycerol Permeability and Metabolism in 3T3-L1 Adipocytes

Aquaglyceroporins—aquaporin membrane channels (AQP) that conduct glycerol and other small neutral solutes in addition to water—play major roles in obesity. In adipocytes, aquaglyceroporins mediate glycerol uptake and release across the plasma membrane, which are two key steps for triacylglycerols (TAGs) synthesis (lipogenesis) and hydrolysis (lipolysis). The aim of this study was to assess both glycerol permeability and metabolism in undifferentiated 3T3-L1 cells (UDCs) as well as in untreated (CTL-DCs) versus lipopolysaccharide (LPS-DCs)-treated differentiated 3T3-L1 adipocytes. Glycerol release, TAGs content and whole membrane glycerol permeability were significantly increased in DCs as compared to UDCs. Moreover, in DCs, LPS treatment significantly increased TAGs content and decreased glycerol permeability. In addition, a significant reduction in whole membrane glycerol permeability was observed in LPS-DCs as compared to CTL-DCs. The relative contributions of AQP3, AQP7 and AQP9 (facilitated diffusion), as well as that of the phospholipid bilayer (simple diffusion), to the whole membrane glycerol permeability, were estimated biophysically in UDCs, CTL-DCs and LPS-DCs, using selective AQP inhibitors. Further studies will be required to determine if modifications in either subcellular localization and/or activity of aquaglyceroporins could account for the data herein. Nevertheless, our findings provide novel insights in understanding the LPS-induced adipocyte hypertrophy that accompanies obesity.
Efficacy of an educational programme for secondary school students on opinions on renal transplantation and organ donation: a randomized controlled trial.

CONTEXT Organ shortage for transplantation is a crucial problem; educational interventions may increase donations and decrease opposition. OBJECTIVE To test the efficacy of an educational programme on opinions on organ transplantation and kidney donation. DESIGN AND PARTICIPANTS Cluster Randomized Controlled Trial: eight intervention and eight control schools were randomly selected from the 33 public schools that agreed to participate. Targets: students in the last 2 years of secondary school (17-18 years); seven schools per group completed the study. EDUCATIONAL PROGRAMME: INTERVENTION first questionnaire (anonymous); 2 h lesson in each class; 2 h general session with patients and experts; second questionnaire. CONTROL questionnaires. MAIN OUTCOME MEASURES Differences between questionnaires (comparative analysis); interest; satisfaction with the programme; (cross-sectional analysis). RESULTS 1776 first, 1467 second questionnaires were retrieved. Living kidney donation: at baseline 78.8% of students would donate a kidney to a relative/friend in need. The answers were unaffected by type of school but depended on sex (females more prone to donate, P<0.001); the answers did not change after the lessons. Cadaveric kidney donation: baseline opinions were mixed (intervention schools: 31.5% yes, 33.7% no, 34.8% uncertain), depending on type of school (classical-scientific high schools more positive than technical institutes, P<0.001), sex (males more prone to donate, P<0.001). Answers on living and cadaveric donation were correlated (P<0.001). The educational intervention increased favourable (31.5 to 42.9%) and uncertain (34.8 to 41.1%) opinions and decreased negative ones (33.7 to 16%) (P<0.001). CONCLUSIONS Educational interventions are effective in increasing interest and improving opinions about cadaveric organ donation.
Healthy Lifestyle Behaviors and Health Promotion Attitudes in Preregistered Nurses: A Questionnaire Study.

BACKGROUND Nurses report inadequacies in health promotion practices. This study investigated attitudes toward being role models for healthy eating, and examined predictors of health promotion attitudes in preregistered nurses. METHOD A questionnaire was completed by 493 preregistered nurses. Measures included health promotion attitudes, healthy lifestyle index, self-esteem, and body satisfaction. RESULTS Preregistered nurses (89.5%) felt that nurses should be role models for health. However, 37% had a negative health promotion attitude and were more likely to be dissatisfied with their body and lead less healthy lifestyles. Most preregistered nurses (96%) felt that delivering health promotion would be a key element of their job and held positive health promotion attitudes. Healthy lifestyle was the most consistent significant predictor of health promotion attitude. CONCLUSION Preregistered nurses with an unhealthy lifestyle and lower self-esteem held a more negative health promotion attitude. Intervention is needed to support preregistered nurses in making healthy lifestyle choices, improving their self-perception and health promotion attitude. [J Nurs Educ. 2017;56(2):94-103. ].
Collaborative e-learning through open social student modeling and Progressive Zoom navigation

Students usually do not study individually; instead, they tend to study collaboratively. The “power of known peers” can be embraced to provide implicit navigation support for collaborative social e-learning environments. In this paper, we present a novel approach to collaborative e-learning through open social student modeling with Progressive Zoom navigation support. Progressive Zoom is a Google-Maps paradigm which seeks to address information overload issues. It enables students to zoom in or out in a multi-layer fashion, so students can reflect on their individual and peer progress based on the knowledge and pedagogical context. In our initial survey, all students were satisfied with the navigation interface and would recommend the interface to their classmates.