Miracle-dz/UniFAR-FTUs huggingface dataset:
Predicting decisions to purchase from sponsors of the Vancouver 2010 Olympics

Our purpose was to understand motivational factors associated with peoples' decision to purchase products/services from sponsors of the Vancouver 2010 Olympics. To achieve this purpose, we employed and extended Ajzen's theory of planned behaviour (TPB). A three-phase, mixed method data collection process was completed among a sample of young adults living in Canada (N = 471). Our extended TPB model accounted for 61% of the variance in intention and 58% of the variance in self-reported purchase behaviour. Attitude toward the behaviour, subjective norms, descriptive norms and past behaviour emerged as significant predictors of purchase intention. Intention, in turn, predicted self-reported purchase behaviour. We conclude that the TPB can offer sponsorship researchers a sound theoretical model for understanding purchase decisions. Implications for sponsorship marketers are discussed.
Endometrial Morphology During Long‐Term Use of Levonorgestrel‐Releasing Intrauterine Devices

Summary Levonorgestrel-releasing intrauterine devices (IUD) were inserted in 92 women. Endometrial biopsies were taken between 3 months and 7 years after these insertions. Intrauterine release of Levonorgestrel resulted in endo-metrial glandular atrophy and decidualized stroma. Inflammation and necrosis were also seen as local signs of IUD use. The biopies were similar regardless of the duration of IUD use. Endometrial morphology returned to normal in biopsy specimens taken 1–3 months after IUD removal.
VEGF Levels in Plasma in Relation to Platelet Activation, Glycemic Control, and Microvascular Complications in Type 1 Diabetes

OBJECTIVE Increased levels of vascular endothelial growth factor (VEGF) in human plasma samples have suggested that circulating VEGF is a cause of endothelial dysfunction in diabetes mellitus. However, artificial release of VEGF from platelets as a source of VEGF in plasma samples, as also occurs in serum samples, has not been ruled out in these studies. RESEARCH DESIGN AND METHODS We determined VEGF levels in plasma collected in both citrate and PECT, a medium that inactivates platelets, in a cross-sectional cohort of 21 healthy subjects and 64 patients with type 1 diabetes. In addition, we evaluated whether VEGF levels in both types of plasma correlated with the presence of diabetes, glycemic control, markers of in vivo or ex vivo platelet activation, and degree of diabetic retinopathy and nephropathy. RESULTS VEGF levels were invariably low in PECT plasma of both nondiabetic and diabetic subjects and were unrelated to any other diabetes-related variable studied. In contrast, VEGF levels in citrate plasma were 150% higher in diabetic patients than in control subjects and correlated with diabetes-related variables. Multiple linear regression analysis showed that levels of platelet factor 4, a marker for ex vivo platelet activation, and HbA1c were the independent predictors of VEGF levels in citrate plasma. Platelet activation, in vivo and ex vivo, was similar in diabetic persons and control subjects. CONCLUSIONS Like serum, citrate plasma is not suitable for reliable measurements of circulating VEGF. The low levels of VEGF in vivo, as represented by measurements in PECT plasma in our study, do not support a role of circulating VEGF in endothelial dysfunction in type 1 diabetes. Higher levels of VEGF in citrate plasma samples of diabetic persons do not represent the in vivo situation, but mainly originate from higher artificial ex vivo release from platelets correlating with the degree of glycemic control.
An international survey of predictive genetic testing in children for adult onset conditions

Purpose: Predictive genetic testing is offered to asymptomatic adults even when there is no effective prophylaxis or treatment. Testing of young people in similar circumstances is controversial, and guidelines recommend against it. We sought to document descriptive examples of the occurrence of genetic testing in young people for nonmedical reasons, in the countries where guidelines exist.Methods: Clinical geneticists in the USA, Canada, UK, Australia, and New Zealand were surveyed about the occurrence and outcomes of testing in asymptomatic young people for conditions where no prophylaxis or treatment exists and onset is usually in adulthood.Results: Of 301 responses, details were provided of 49 cases where such testing had occurred. The most common condition tested for was Huntington Disease. In 22 cases (45%), the young person tested was immature, defined as under the age of 14 years. Results were disclosed to only two immature minors and in three cases parents experienced clinically significant anxiety related to how they would pass on information to their gene positive child. In 27 cases (55%), the young person tested was mature. Results were disclosed to 26 mature minors and it was reported that two individuals experienced an adverse event. Consistent follow-up did not take place and findings represent the minimum frequency of adverse events. The majority of respondents agree with existing guidelines but many believe each case must be considered individually.Conclusion: Clinicians agree with existing guidelines regarding predictive testing in young people, but choose to provide tests for nonmedical reasons in specific cases.
Effect of Perioperative Oxygen Supplementation on 30-day Surgical Site Infection Rate in Abdominal, Gynecologic, and Breast Surgery: The ISO2 Randomized Controlled Trial

Background: Benefits and limitations of supplementation with 80% fraction of inspired oxygen for preventing surgical site infections have not yet been clearly defined. Some studies have reported benefits in colorectal surgery, whereas trials in abdominal and gynecologic surgery have reported either no effect or a deleterious effect. Methods: Controlled, randomized, assessor-blind multicenter trial, the ISO2 study, comparing the effects of hyperoxygenation (fraction of inspired oxygen, 80%) with those of 30% oxygen on the frequency of surgical site infections in routine abdominal, gynecologic, and breast surgery on 434 patients. Patients not seen in consultation after discharge were contacted. Results: In total, 208 patients received 30% perioperative oxygen and 226 received 80%. There was no difference between the two groups for baseline, intraoperative, and postoperative characteristics, except for oxygen saturation at closure, higher in the 80% group (P = 0.01). The frequency of 30-day surgical site infections was 7.2% (15/208) in the 30% group and 6.6% (15/226) in the 80% group (relative risk, 0.92; 95% CI [0.46–1.84], P = 0.81). Frequency of adverse events (nausea and vomiting, sternal pain, cough, hypotension) was similar in the two groups. Desaturation and bradycardia were more frequent in the 30% group. In an updated meta-analysis including the result of this trial and those of eight published randomized trials, the overall relative risk was 0.97; 95% CI (0.68–1.40), I2 (inconsistency degree) = 73%, (P = 0.88). Conclusions: The routine use of hyperoxygenation throughout abdominal, gynecologic, and breast surgery had no effect on the frequency of 30-day surgical site infections and was not accompanied by more frequent adverse effects.
Prior Affirmative Representation Facilitates the Cognitive Processing of Compound Negation

A mixed factorial design of 2x2x2 was applied (sequence x law x affirmation) to evaluate the effects of prior affirmative representation on the subsequent processing of compound negation. The sequence factor was defined to perform between-subjects comparisons. The other two factors, that is, logic law and prior affirmation were defined as within-subjects factors. The sequence factor was included to evaluate potential artifacts generated by the experimental design. Statistical analyses showed the absence of such artifacts. Three dependent variables were included: response type, an indirect measure of introspection quality, and a direct measure of subjective difficulty. A random sample of 130 participants were recruited for this experiment. All the participants were undergraduate students at the National University of Entre Rios, Argentina. 112 were female (86.2%). The mean age was 23.79 years old (SD = 6.452). 2 sets of 6 exercises each were given to all the participants. The classical selection paradigm was applied, that is, four response options were given in each item. Only one of them was the normative response according to logic (DeMorgan’s equivalences for negated conjunctions and negated disjunctions). One set included prior relevant affirmation before requiring negation, the other set started straightforward with the negation task. The task was to find the logical meaning of such compound negation that operated on a conjunction or a disjunction. By the other side, the set of exercises without prior affirmation asked straightforward to find the equivalence for a given compound negation of a conjunction or a disjunction. After completing each set of 6 responses participants were asked to give an opinion about their own performance (introspection quality) and about the task difficulty (subjective difficulty). In consistence with the mental models theory and the relevance theory, prior affirmation increased the frequency of normative responses and the quality of introspection. However, a direct registry of task difficulty showed no difference between a prior affirmation condition and a straightforward condition in consistence with the Gricean view of negation. An unexpected result showed an incremental effect of normative responses for the negation of conjunctions in comparison with the negation of disjunctions when prior affirmation provided a pragmatically enriched context. These results are discussed in terms of working memory dynamics. In sum, our findings suggest that the processing of compound negation of conjunctions and disjunctions can be explained as a combination of explicit and implicit processes that are strongly influenced by pragmatic factors.
A Comparison of White-Collar Offenders and Non-White-Collar Offenders on the Psychological Variables of Personality, Criminal Thinking, and Psychopathy

A Comparison of White-Collar Offenders and Non-White-Collar Offenders on the Psychological Variables of Personality, Criminal Thinking, and Psychopathy Laurie Ragatz The first purpose of this study was to replicate Walters and Geyer (2004) by examining how white-collar offenders differ from non-white-collar offenders on criminal thinking styles and lifestyle criminality. The second purpose was to examine the psychopathic characteristics of white-collar offenders in comparison to non-white-collar offenders. The third purpose was to explore the psychopathology of white-collar offenders compared to non-white-collar offenders. The study sample included 48 white-collar only offenders (offenders that only committed whitecollar crime), 89 white-collar versatile offenders (offenders that have previously committed nonwhite-collar crime), and 89 non-white-collar offenders. Groups were matched on age and ethnicity. All participants completed the Psychological Inventory of Criminal Thinking Styles (PICTS), the Psychopathic Personality Inventory-Revised (PPI-R), and the Personality Assessment Inventory (PAI). The Lifestyle Criminality Screening Form (LCSF) was completed using participants’ Presentence Investigation Reports (PSIs). Results demonstrated white-collar only offenders had lower scores on the PICTS Sentimentality scale and LCSF. Additionally, white-collar offenders scored higher on PPI-R subscales (i.e., Social Potency and Machiavellian Egocentricity) and PAI scales (i.e., Alcohol Problems and Anxiety-Related Disorders). Nonwhite-collar offenders had higher scores on the PAI Drug Problems scale. Logistic regression findings demonstrated PAI Drug and Alcohol Problem scales distinguished white-collar versatile and non-white-collar offenders. White-collar only offenders were differentiated from non-whitecollar offenders by the PAI Anxiety-Related Disorders scale, PAI Drug Problems scale, PAI Alcohol Problems scale, and PPI-R total score. The logistic regression model was not significant for distinguishing white-collar only and white-collar versatile offenders. Research findings have implications for treatment practices with white-collar offenders.
INTERPRETING RELIGIOUS PLURALISM: COMPARATIVE RESEARCH AMONG CHRISTIAN, MUSLIM AND HINDU STUDENTS IN TAMIL NADU, INDIA

How do Christians, Muslims and Hindus interpret religions other than their own? The theoretical framework of the research is models of religious pluralism developed by scholars in the field of theology of religions, especially Knitter. The authors pay special attention to pluralistic models, which have so far remained rather unclear. Special attention is paid to gender as a factor influencing levels of agreement with models of religious pluralism. Empirical research undertaken among Christian, Muslim and Hindu college students in Tamil Nadu in 2003 reveals three common models of religious pluralism that can be found among the adherents of these traditions: monism, commonality pluralism, and differential pluralism. Christian and Muslim students have much the same approach to religious pluralism, measured according to these three models; Hindu students differ from both Christian and Muslim students. Especially among Muslim students gender influences the level of agreement with the monism and commonality models. The article concludes with a discussion of the fruitfulness of comparative research (among members of different religious traditions) based on models derived from Christian theology.
Restoring Christian Leaders

Abstract In this article, we examined factors that might be associated with restoring pastorsto wholeness. We began with an example of a pastor's extramarital affair that can have far reaching effects on various members within a community of faith. Next, we examined the concepts of transgression and stress, forgiveness, reconciliation, and restoration used in recent empirical studies. We suggested how certain nuances such as state and process conceptualizations might make a difference in clinical practice. Finally, we offered suggestions for clinical practice and research.
Mining Public Opinions on Real Estate Prosperity from Internet: a Beijing Study

Real estate market prosperity is crucial to a nation’s economy as well as people’s livelihood, especially for the emerging economy. In China, the real estate market has been overheated since the reform of urban housing system in 1998. Due to the price diversity and region variations, the traditional real estate indicators released by the government became insufficient in explaining local real estate market prosperities. People keep questioning the consistency of the official statistics and the market reality they perceives in their everyday life. This research is an attempt to introduce a sentiment index drawing from Internet data to represent public opinions on real estate market, which reflects the prosperity of real estate market, and contains sentiment information of the society. Methods of data source selection, keywords selection, index construction and index evaluation are proposed and discussed. Empirical results on Beijing real estate market suggest that the proposed index has a strong explanatory power to estimate aggregate real estate indicators, and individual house rent. It is capable to reflect prosperity of the real estate market of Beijing. The index is particular useful to capture public sentiments and expectations on real estate markets and offer insights on future real estate market dynamics.
Oncogenes and Tumor Suppressors Dynamic Interactions between Cancer Cells and the Embryonic Microenvironment Regulate Cell Invasion and Reveal EphB 6 as a Metastasis Suppressor

Metastatic dissemination drives the highmortality associatedwithmelanoma.However, difficulties in visualizing in vivo cell dynamics during metastatic invasion have limited our understanding of these cell behaviors. Recent evidence has revealed that melanoma cells exploit portions of their ancestral embryonic neural crest emigration program to facilitate invasion. What remains to be determined is how embryonic microenvironmental signals influence invasivemelanoma cell behavior, andwhether these signals are relevant to human disease. To address these questions, we interrogated the role of the neural crest microenvironment in dictating the spatiotemporal pattern of melanoma cell invasion in the chick embryo using 2-photon time-lapse microscopy. Results reveal that both permissive and inhibitory neural crest microenvironmental signals regulate the timing and direction of melanoma invasion to coincide with the neural crest migration pattern. These cues include bidirectional signaling mediated through the ephrin family of receptor tyrosine kinases. We demonstrate that EphB6 reexpression forces metastatic melanoma cells to deviate from the canonical migration pattern observed in the chick embryo transplant model. Furthermore, EphB6-expressing melanoma cells display significantly reduced metastatic potential in a chorioallantoic membrane (CAM) metastasis assay. These data on melanoma invasion in the embryonic neural crest and CAM microenvironments identify EphB6 as a metastasis suppressor in melanoma, likely acting at the stage of
(Im)Mobile bodies: Contemporary semi-professional dancers’ experiences with injuries

The purpose of this research was to examine semi-professional contemporary dancers’ experiences with injuries. Similar to athletes, dancers are often injured. Much of the previous research on dance injuries, however, has focused on ballet where the professional requirements and high technical level create demanding work conditions. Semi-professional contemporary dance differs from this context due to its technique and work environment. In this study, I investigate how contemporary dancers experience injuries. From a Deleuzian perspective, I examine the connections between the body, injury, and the dancing identity within the culture of contemporary dance. The empirical material from semi-structured interviews revealed that while most participants suffered injuries, they generally ignored their injuries and continued to dance as, they argued, their passion for contemporary dance overrode the need for caring for their injuries. Consequently, the cultural environment for amateur dance facilitated injury experiences similar to professional dance.
Domestic Violence and Forced Sex Among the Urban Poor in South India

This article examined the prevalence of physical and sexual violence among 1,974 married women from 40 low-income communities in Chennai, India. The authors found a 99% and 75% lifetime prevalence of physical abuse and forced sex, respectively, whereas 65% of women experienced more than five episodes of physical abuse in the 3 months preceding the survey. Factors associated with violence after multivariate adjustment included elementary/middle school education and variables suggesting economic insecurity. These domestic violence rates exceed those in prior Indian reports, suggesting women in slums may be at increased risk for HIV and other sexually transmitted infections.
The effects of allelic dosage and graft size on skin graft survival across a weak histocompatibility barrier.

Normal skin was grafted between congenic strains of mice to test the effect of allelic dosage at the weak H-1 locus. Heterozygous grafts survived longer than homozygous grafts when placed on different A hosts. The same difference was noted when both grafts were put on opposite sides of the same A host. Both allelic types gave a direct relationship between graft size and survival time over a wide size range, but the slope of the heterozygous dose—response curve was much steeper, with some of the large grafts surviving permanently. Grafts in the combination male to male survived longer than those in the combination female to female. The results are discussed in terms of a possible distinction between antigen available for the afferent and efferent immunological pathways.
Where One Hand Meets the Other: Limb-Specific and Action-Dependent Movement Plans Decoded from Preparatory Signals in Single Human Frontoparietal Brain Areas

Planning object-directed hand actions requires successful integration of the movement goal with the acting limb. Exactly where and how this sensorimotor integration occurs in the brain has been studied extensively with neurophysiological recordings in nonhuman primates, yet to date, because of limitations of non-invasive methodologies, the ability to examine the same types of planning-related signals in humans has been challenging. Here we show, using a multivoxel pattern analysis of functional MRI (fMRI) data, that the preparatory activity patterns in several frontoparietal brain regions can be used to predict both the limb used and hand action performed in an upcoming movement. Participants performed an event-related delayed movement task whereby they planned and executed grasp or reach actions with either their left or right hand toward a single target object. We found that, although the majority of frontoparietal areas represented hand actions (grasping vs reaching) for the contralateral limb, several areas additionally coded hand actions for the ipsilateral limb. Notable among these were subregions within the posterior parietal cortex (PPC), dorsal premotor cortex (PMd), ventral premotor cortex, dorsolateral prefrontal cortex, presupplementary motor area, and motor cortex, a region more traditionally implicated in contralateral movement generation. Additional analyses suggest that hand actions are represented independently of the intended limb in PPC and PMd. In addition to providing a unique mapping of limb-specific and action-dependent intention-related signals across the human cortical motor system, these findings uncover a much stronger representation of the ipsilateral limb than expected from previous fMRI findings.
DNA Vaccines Approach: From Concepts to Applications

DNA vaccines are the third generation vaccines based on purified plasmid preparations containing transgenes that encode antigenic/therapeutic proteins or peptides capable of triggering an immune response against a wide range of diseases. This vaccine platform presents several attributes that confer distinct advantages over other vaccine technologies in terms of safety, ease of fabrication and stability. Many aspects, such as antigen expression and especially vector design, are under study because of their great influence on immunogenicity and efficacy of DNA vaccines. In this regard, with the attempt of improving the efficiency of DNA vaccines, co-expression of stimulatory sequences and diverse vector delivery systems are being optimized. With this in mind, this review aims to giving a conceptual approach of DNA vaccines, explaining their mechanisms of action and listing the already licensed veterinary DNA vaccines presented in the market.