Miracle-dz/UniFAR-FTUs huggingface dataset:
Meaning and coping orientation of bereaved parents: Individual and dyadic processes

The present study aimed to examine whether bereaved parents “meaning-made”–defined as results of attempts to reduce discrepancies between the meaning assigned to the death of the child and self and world-views—was influenced by their own and their partner’s coping orientations. Coping orientations were conceptualized within the Dual Process Model, which entails loss coping orientation (LO; focus on the loss itself), restoration coping orientations (RO; focus on stressors that come about as an indirect consequence of the bereavement), and a flexible oscillation between both coping orientations. The sample consisted of 227 couples identified through obituary notices in local and national newspapers, who provided data at 6, 13, and 20 months after the death of their child. At all three points of measurement, both partners independently completed the Dual Coping Inventory (DCI) and a scale developed by the authors about meaning-made from the loss. Data were analyzed using a multi-level Actor-Partner Interdependence Model. Results show that the combination of parents’ own LO and RO (operationalized through the interaction effect between LO and RO) have a positive effect in parents’ meaning-made. Partners’ LO have a negative effect in parents’ meaning-made. These results highlight the importance of, in the context of parental bereavement, being flexible by using both coping orientations, and of acknowledging the interdependence between partners, namely, the interpersonal process by which partner’s coping affect one’s meaning-made.
Advances in methods for determining fecundity: application of the new methods to some marine fishes

Estimation of individual egg production (realized fecundity) is a key step either to understand the stock and recruit relationship or to carry out fisheries-independent assessment of spawning stock biomass using egg production methods. Many fish are highly fecund and their ovaries may weigh over a kilogram; therefore the work time can be consuming and require large quantities of toxic fixative. Recently it has been shown for Atlantic cod (Gadus morhua) that image analysis can automate fecundity determination using a power equation that links follicles per gram ovary to the mean vitellogenic follicular diameter (the autodiametric method). In this article we demonstrate the precision of the autodiametric method applied to a range of species with different spawning strategies during maturation and spawning. A new method using a solid displacement pipette to remove quantitative fecundity samples (25, 50, 100, and 200 milligram [mg]) is evaluated, as are the underlying assumptions to effectively fix and subsample the ovary. Finally, we demonstrate the interpretation of dispersed formaldehyde-fixed ovarian samples (whole mounts) to assess the presence of atretic and postovulatory follicles to replace labor intensive histology. These results can be used to estimate down regulation (production of atretic follicles) of fecundity during maturation.
Internal evaluation of a physically-based distributed model using data from a Mediterranean mountain catchment

Abstract. An evaluation of the performance of a physically-based distributed model of a small Mediterranean mountain catchment is presented. This was carried out using hydrological response data, including measurements of runoff, soil moisture, phreatic surface level and actual evapotranspiration. A-priori model parameterisation was based as far as possible on property data measured in the catchment. Limited model calibration was required to identify an appropriate value for terms controlling water loss to a deeper regional aquifer. The model provided good results for an initial calibration period, when judged in terms of catchment discharge. However, model performance for runoff declined substantially when evaluated against a consecutive, rather drier, period of data. Evaluation against other catchment responses allowed identification of the problems responsible for the observed lack of model robustness in flow simulation. In particular, it was shown that an incorrect parameterisation of the soil water model was preventing adequate representation of drainage from soils during hydrograph recessions. This excess moisture was then being removed via an overestimation of evapotranspiration. It also appeared that the model underestimated canopy interception. The results presented here suggest that model evaluation against catchment scale variables summarising its water balance can be of great use in identifying problems with model parameterisation, even for distributed models. Evaluation using spatially distributed data yielded less useful information on model performance, owing to the relative sparseness of data points, and problems of mismatch of scale between the measurement and the model grid. Keywords: physically-based distributed model, SHETRAN, parameterisation, Mediterranean mountain catchment, internal evaluation, multi-response
Myocardial Blood Flow and Flow Reserve After Coronary Reimplantation in Patients After Arterial Switch and Ross Operation

BackgroundCoronary reimplantation is used in therapy for congenital heart disease, such as in the arterial switch (ASO) and Ross operations. The adequacy of myocardial perfusion may remain a matter of concern. The aim of the present study was to stratify the effect of coronary reimplantation on myocardial perfusion and to highlight the clinical relevance of any attenuation in myocardial perfusion. Methods and ResultsA total of 21 children with transposition of the great arteries at a mean interval of 11.2±2.9 years after ASO and 9 adolescents at a mean interval of 4.2±2.1 years after the Ross procedure were investigated. All patients were asymptomatic and had a normal exercise capacity. On stress echocardiography, 2 of the ASO patients had dyskinetic areas within the left ventricular myocardium, and 5 had adenosine-induced perfusion defects on positron emission tomography. No coronary obstruction was detected on coronary angiography in any patient, but a common finding was right coronary dominance and a small caliber of the distal part of the left anterior descending artery. Coronary flow reserve (CFR) was significantly reduced in all patients after ASO when compared with 10 normal healthy volunteers (age, 25.6±5.3 years). CFR was normal in the 9 patients who had the Ross operation (age, 19.2±7.6 years); exercise-induced perfusion defects were not detected in the Ross patients. ConclusionsChildren after ASO are asymptomatic, without clinical signs of coronary dysfunction. In contrast to patients who had the Ross operation, stress-induced perfusion defects and an attenuated CFR were documented. The prognostic implications of these findings and the clinical consequences are unclear; nevertheless, close clinical follow-up of ASO patients is mandatory.
Determination of endosperm characteristics of 38 corn hybrids using the Stenvert Hardness Test

Grain hardness characteristics for a range of corn hybrids were measured using a modified Stenvert Hardness Test (SHT). A computer-based data logging and analysis system was constructed to obtain the milling time and transient power consumption during the milling process, from which milling energy and peak power demand were calculated. In addition, the time taken to mill 17 ml of flour (resistance time) and the height of the milled 20-g sample in the collection tube were recorded. The SHT measurements were correlated with the ratio of hard to soft endosperm and the bulk density of the grain. Thirty eight hybrid corn cultivars were tested. It was found that the testing system was simple and easy to use and error variation was low. Results indicate that significant variation in the measured parameters occurred among the hybrids. SHT parameters were highly correlated with the ratio of hard to soft endosperm. Statistical analysis using analysis of variance showed that significant differences occurred among the hybrids for the variables measured. Principal component analysis showed that the milling energy and resistance time were the most effective SHT parameters for assessing grain hardness. Both parameters were highly correlated with the ratio of hard to soft endosperm and the bulk density of the grain. Cluster analysis indicated that endosperm characteristics were genetically controlled and associated with germplasm groups.
Amoxicillin-Clavulanate Therapy Increases Childhood Nasal Colonization by Methicillin-Susceptible Staphylococcus aureus Strains Producing High Levels of Penicillinase

ABSTRACT We examined factors associated with penicillinase production by nasal carriage Staphylococcus aureus strains in 648 children aged 3 to 6 years attending 20 randomly sampled playschools. The children were prospectively monitored for drug use and medical events for 6 months and were then screened for S. aureus carriage. Isolates were tested for their susceptibility to penicillin G and methicillin, and penicillinase production by methicillin-susceptible, penicillin-resistant strains was quantified. S. aureus was isolated from 166 children (25.6%). Exposure to amoxicillin-clavulanate during the previous 3 months was associated with higher penicillinase production by penicillin-resistant, methicillin-susceptible strains (odds ratio, 3.6; P = 0.03). These results suggest that use of the amoxicillin-clavulanate combination could induce a herd selection process of S. aureus strains producing higher levels of penicillinase.
On Local Models with Special Parahoric Level Structure

We consider the local model of a Shimura variety of PEL type, with the unitary similitudes corresponding to a ramified quadratic extension of $\mathbb{Q}_p$ as defining group. We examine the cases where the level structure at $p$ is given by a parahoric that is the stabilizer of a selfdual periodic lattice chain and that is special in the sense of Bruhat--Tits theory. We prove that in these cases the special fiber of the local model is irreducible and generically reduced; consequently, the special fiber is reduced and is normal, Frobenius split, and with only rational singularities. In addition, we show that in these cases the local model contains an open subset that is isomorphic to affine space.
The Ohio State University 1966-09 Toxicity of Microcystis Waterbloom from an Ohio

A toxin extracted from a waterbloom of the blue-green alga Microcystis aeruginosa was found to have an LDioo to mice of 3 mg/kg. Death occurred in less than 4 hours and was accompanied by symptoms corresponding to those of the fast death factor found by others in blue-green algae. The toxin was found to have no effects on three species of fish and a microcrustacean in concentrations up to 10 mg/1, and showed no growth-inhibitory effects on a diatom.
Drug resistant Shigella flexneri in & around Dibrugarh, north-east India

Background & objectives: Shigella flexneri is the most common species of Shigella causing diarrhoea and dysentery in Asia including India. Multidrug resistance in Shigella species has been reported worldwide and there is rising concern regarding development of fluoroquinolone resistance. This study was undertaken to find out the resistance pattern of Sh. flexneri, the commonest shigella isolated in Dibrugarh, north east India, including detection of fluoroquinolone resistance and extended spectrum beta lactamases. Methods: Stool samples collected from patients of diarrhoea and dysentery were tested for bacterial enteropathogens. Strains of Shigella species were confirmed by biochemical tests. Speciation was done using commercially available polyvalent antiserum. Antimicrobial susceptibility test was performed by Kirby Bauer disc diffusion method against 18 different antibiotics. Extended spectrum beta lactamase (ESBL) detection was done by disc approximation test as well as combination disc method and minimum inhibitory concentrations (MIC) of different antibiotics were also measured. Results: Multidrug resistance in Sh. flexneri was found to be common (90.2%) and the commonest phenotypic multi-drug resistance profile was ampicillin-tetracycline-co-trimoxazole-nalidixic acid. High resistance to nalidixic acid was detected in 90.3 per cent isolates (MIC >240 μg/ml) and ciprofloxacin resistance was seen emerging in this region (11.2%, MIC >4 μg/ml). Present of ESBL was phenotypically confirmed in two cases. Besides the fluoroquinolones, chloramphenicol, piperacillin-tazobactum and the third generation cephalosporins were effective in 87-100 per cent of the isolates. Interpretation & conclusions: Our study showed high resistance (MIC >240 μg/ml) against nalidixic acid in Sh. flexneri isolates. Ciprofloxacin resistance is also emerging in this region. Shigellosis due to ESBL carrying Shigella can become a serious threat to public health. Guidelines for therapy should be monitored and modified based on regional reports of resistance to antimicrobial agents.
THE STUDENTS’ PERCEPTIONS: ESSAY VERSUS MULTIPLE-CHOICE TYPE EXAMS

The purpose of this study was to examine students’ perceptions toward essay versus multiplechoice exams. Fifty students from a science education department participated in this study. Overall studentrating data revealed that students showed significantly (p<0.001) more favorable attitudes towards multiple choice test format compared to essay type formats in terms of the most critical dimensions assessed. These findings suggest that student perceptions should be taken into consideration while planning and constructing classroom testing. Suggestions for future research and implications for having students’ perceptions are also discussed.
Image Denoising using Gaussian Scale Mixtures in the Wavelet Domain

We describe a method for removing noise from digital images, based on a statistical model of the coecien ts of an overcomplete multi-scale oriented basis. Neighborhoods of coecien ts at adjacent positions and scales are modeled as the product of two independent random variables: a Gaussian vector and a hidden positive scalar multiplier. The latter modulates the local variance of the coecien ts in the neighborhood, and is thus able to account for the empirically observed correlation between the amplitudes of pyramid coecien ts. Under this model, the Bayesian least squares estimate of each coecien t reduces to a weighted average of the local linear (Wiener) estimate over all possible values of the hidden multiplier variable. We demonstrate through simulations with images contaminated by additive Gaussian noise of known covariance that the performance of this method substantially surpasses that of previously published methods, both visually and in terms of mean squared error. In addition, we demonstrate the performance of the algorithm in removing sensor noise from high-ISO digital camera images.
As Good as the Real Thing? A Comparative Study of Interpretive Podcasts and Traditional Ranger Talks

This study compared the effectiveness of three interpretive formats: online podcasts, the same podcasts viewed at a park's visitor center (VC), and traditional ranger talks. Programs covered eight different topics but were all presented by the same interpreter. After viewing a program, visitors completed surveys assessing their emotional and intellectual responses and feelings of stewardship. Responses from talk participants were slightly stronger than those of both online podcast and VC podcast viewers for most indicators, especially smiles and intent to change behavior based on program content (p ≤ .01). Online podcast responses were stronger than VC podcast responses, particularly for viewers’ enjoyment, smiles, and level of personal interest (p ≤ .01). Podcasts viewed in the VC generated the weakest overall responses. Many of the differences between online podcast and ranger talk responses, though statistically significant, were not practically significant. These results provide initial empirical evidence to justify parks’ increasing investment in new media interpretation.
A Hierarchical Multilayer Service Composition Model for Global Virtual Organizations

A major benefit of service composition is the ability to support agile global collaborative virtual organizations. However, being global in nature, collaborative virtual organizations can have several virtual industry clusters (VIC), where each VIC has hundreds to thousands of virtual enterprises that provide functionally similar services exposed as web services. These web services can be differentiated on a high dimensionality of quality of service attributes. The dilemma the virtual enterprise broker is faced with is how to dynamically select the best combination of component services to fulfill a complex consumer need within the shortest time possible. This composite service selection problem remains a Multi-Criteria Decision Making (MCDM) NP hard problem. Although existing MCDM methods based on local planning are linearly scalable for large problems, they lack capabilities to express critical intertask constraints that are practically relevant to service consumers. MCDM global planning methods on the other hand suffer exponential state space explosion making them severely limited for large problems of industrial relevance. This paper proposes HMSCM: Hierarchical Multi-Layer Service Composition Model. HMSCM is based on the theory of Layering as Optimization Decomposition (28-31). We view the service selection process as a "two layer network" where each layer is a subproblem to be solved. The objective of one of the layers is to maximize a local utility function over a subset of web service QoS attributes from a service consumer perspective. The objective of the other layer is to maximize a local utility function over another subset of web service QoS attributes from the perspective of the Virtual enterprise broker. We develop the algorithm: Service Layered Utility Maximization (SLUM) that extends the Mixed Integer programming model in (9). We then formulate the problem at each layer in form of SLUM. Together, the two layers attempt to achieve the global optimization objective of the network. We show analytically how HMSCM overcomes the shortcomings of existing local planning and global planning service selection methods while retaining the strengths from each. i.e HMSCM is able to scale linearly with increasing number of QoS variables and number of web services while being able to enforce global intertask constraints.
Elevated intra-abdominal pressure limits venous return during exercise in Varanus exanthematicus

SUMMARY The effects of treadmill exercise on components of the cardiovascular (venous return, heart rate, arterial blood pressure) and respiratory systems (minute ventilation, tidal volume, breathing frequency, oxygen consumption, carbon dioxide production) and intra-abdominal pressure were investigated in the Savannah monitor lizard, Varanus exanthematicus B. , at 35°C. Compared with resting conditions, treadmill exercise significantly increased lung ventilation, gular pumping, intra-abdominal pressure, mean arterial blood pressure and venous return (blood flow in the post caval vein). However, venous return declines at high levels of activity, and mean arterial pressure and venous return did not attain peak values until the recovery period, immediately following activity. Elevating intra-abdominal pressure in resting lizards (via saline infusion) resulted in significant reductions in venous return when the transmural pressure of the post caval vein became negative (i.e. when intra-abdominal pressure exceeded central venous pressure). Together these results suggest that increments in intra-abdominal pressure compress the large abdominal veins and inhibit venous return. During locomotion, the physical compression of the large abdominal veins may represent a significant limitation to cardiac output and maximal oxygen consumption in lizards.
Time-Bounded Essential Localization for Wireless Sensor Networks

In many practical applications of wireless sensor networks, it is crucial to accomplish the localization of sensors within a given time bound. We find that the traditional definition of relative localization is inappropriate for evaluating its actual overhead. To address this problem, we define a novel problem called {\em essential localization}, and present the first rigorous study on the essential localizability of a wireless sensor network within a given time bound. We propose an efficient distributed algorithm for time-bounded essential localization over a sensor network, and evaluate the performance of our algorithm with extensive simulations.
Mechanism of Action of Novel Lung Edema Therapeutic AP301 by Activation of the Epithelial Sodium Channel

AP301 [Cyclo(CGQRETPEGAEAKPWYC)], a cyclic peptide comprising the human tumor necrosis factor lectin-like domain (TIP domain) sequence, is currently being developed as a treatment for lung edema and has been shown to reduce extravascular lung water and improve lung function in mouse, rat, and pig models. The current paradigm for liquid homeostasis in the adult mammalian lung is that passive apical uptake of sodium via the amiloride-sensitive epithelial Na+ channel (ENaC) and nonselective cyclic-nucleotide–gated cation channels creates the major driving force for reabsorption of water through the alveolar epithelium in addition to other ion channels such as potassium and chloride channels. AP301 can increase amiloride-sensitive current in A549 cells as well as in freshly isolated type II alveolar epithelial cells from different species. ENaC is expressed endogenously in all of these cell types. Consequently, this study was undertaken to determine whether ENaC is the specific target of AP301. The effect of AP301 in A549 cells as well as in human embryonic kidney cells and Chinese hamster ovary cells heterologously expressing human ENaC subunits (α, β, γ, and δ) was measured in patch clamp experiments. The congener TIP peptide AP318 [Cyclo(4-aminobutanoic acid-GQRETPEGAEAKPWYD)] activated ENaC by increasing single-channel open probability. AP301 increased current in proteolytically activated (cleaved) but not near-silent (uncleaved) ENaC in a reversible manner. αβγ- or δβγ-ENaC coexpression was required for maximal activity. No increase in current was observed after deglycosylation of extracellular domains of ENaC. Thus, our data suggest that the specific interaction of AP301 with both endogenously and heterologously expressed ENaC requires precedent binding to glycosylated extracellular loop(s).