Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Faith-based and Government-based Adult Education Programs in Western West Virginia

Analysis of Faith-based and Government-based Adult Education Programs in Western West Virginia” By Chad M. Trepinski Faith-based and government-based organizations can provide meaningful adult education programs and services to strengthen a community. Organizations that offer adult education programs are vital partners in community development. This research identifies current adult programs and services offered by seven faith-based and six governmentbased organizations in Huntington, West Virginia. Using a survey of eighty-one potential services or programs, data collected from thirteen community organizations determined what types and how many adult programs are available in Huntington, West Virginia. After identifying current adult programs, interviews with each of the thirteen organizations revealed current faith-based and government-based partnerships; questionnaires with faithbased organizations uncovered sources of government funding. This study demonstrates the capacity of government-based and faith-based organizations to host adult programs, and the importance of partnerships to leverage resources, and minimize duplication of adult programs in a community. TABLE OF CONTENTS ABSTRACT ii TABLE OF CONTENTS iii LIST OF FIGURES iv CHAPTER I
TASI 2008 Lectures on Dark Matter

Based on lectures given at the 2008 Theoretical Advanced Study Institute (TASI), I review here some aspects of the phenomenology of particle dark matter, including the process of thermal freeze-out in the early universe, and the direct and indirect detection of WIMPs. I also describe some of the most popular particle candidates for dark matter and summarize the current status of the quest to discover dark matter's particle identity.
Perilaku Bullying pada Remaja Panti Asuhan Ditinjau dari Kelekatan dengan Teman Sebaya dan Harga Diri

The purpose of this research was to identify and explains the bullying behavior among adolescent, especially in the orphanage. The research was also to investigate the effect of peer attachment and self-esteem on orphanage adolescent of bullying behavior. This research involved about 270 adolescent (13-18 years old, M=15,40 years old, S.D.=1,275) which stayed in 14 orphanages in the Malang city. The collection of data was using the instruments of the Inventory of Parent and Peer Attachment (IPPA), the Rosenberg Self-Esteem Scale (RSES) and the Adolescent Peer Relations Instrument (APRI). The results of this research show us that peer attachment and self-esteem is take effect very significant on orphanage adolescent of bullying behavior.
Browse with a social web directory

Browse with either web directories or social bookmarks is an important complementation to search by keywords in web information retrieval. To improve users' browse experiences and facilitate the web directory construction, in this paper, we propose a novel browse system called Social Web Directory (SWD for short) by integrating web directories and social bookmarks. In SWD, (1) web pages are automatically categorized to a hierarchical structure to be retrieved efficiently, and (2) the popular web pages, hottest tags, and expert users in each category are ranked to help users find information more conveniently. Extensive experimental results demonstrate the effectiveness of our SWD system.
Neurabin: A Novel Neural Tissue–specific Actin Filament–binding Protein Involved in Neurite Formation

We purified from rat brain a novel actin filament (F-actin)–binding protein of ∼180 kD (p180), which was specifically expressed in neural tissue. We named p180 neurabin (neural tissue–specific F-actin– binding protein). We moreover cloned the cDNA of neurabin from a rat brain cDNA library and characterized native and recombinant proteins. Neurabin was a protein of 1,095 amino acids with a calculated molecular mass of 122,729. Neurabin had one F-actin–binding domain at the NH2-terminal region, one PSD-95, DlgA, ZO-1–like domain at the middle region, a domain known to interact with transmembrane proteins, and domains predicted to form coiled-coil structures at the COOH-terminal region. Neurabin bound along the sides of F-actin and showed F-actin–cross-linking activity. Immunofluorescence microscopic analysis revealed that neurabin was highly concentrated in the synapse of the developed neurons. Neurabin was also concentrated in the lamellipodia of the growth cone during the development of neurons. Moreover, a study on suppression of endogenous neurabin in primary cultured rat hippocampal neurons by treatment with an antisense oligonucleotide showed that neurabin was involved in the neurite formation. Neurabin is a candidate for key molecules in the synapse formation and function.
Evaluation of 12-Lipoxygenase (12-LOX) and Plasminogen Activator Inhibitor 1 (PAI-1) as Prognostic Markers in Prostate Cancer

In carcinoma of prostate, a causative role of platelet 12-lipoxygenase (12-LOX) and plasminogen activator inhibitor 1 (PAI-1) for tumor progression has been firmly established in tumor and/or adjacent tissue. Our goal was to investigate if 12-LOX and/or PAI-1 in patient's plasma could be used to predict outcome of the disease. The study comprised 149 patients (age 70 ± 9) divided into two groups: a study group with carcinoma confirmed by positive biopsy of prostate (n = 116) and a reference group (n = 33) with benign prostatic hyperplasia (BPH). The following parameters were determined by the laboratory test in plasma or platelet-rich plasma: protein level of 12-LOX, PAI-1, thromboglobulin (TGB), prostate specific antigen (PSA), C-reactive protein (CRP), hemoglobin (HGB, and hematocrit (HCT), as well as red (RBC) and white blood cells (WBC), number of platelets (PLT), international normalized ratio of blood clotting (INR), and activated partial thromboplastin time (APTT). The only difference of significance was noticed in the concentration of 12-LOX in platelet rich plasma, which was lower in cancer than in BPH group. Standardization to TGB and platelet count increases the sensitivity of the test that might be used as a biomarker to assess risk for prostate cancer in periodically monitored patients.
Effectiveness and predictors of outcome in routine out-patient mental health care for older adults

ABSTRACT Background: Meta-analyses show efficacy of several psychological and pharmacological interventions for late-life psychiatric disorders, but generalization of effects to routine mental health care for older people remains unknown. Aim of this study is to investigate the improvement of functioning within one year of referral to an outpatient mental health clinic for older adults. Methods: Pre-post measurement of the Health of Nations Outcome Scale 65+ (HoNOS 65+) in 704 older people referred for psychiatric problems (no dementia) to any of the seven participating mental health care organizations. Results: The pre-post-test Cohen's d effect size was 1.08 in the total group and 1.23 in depressed patients, the largest subgroup. Linear regression identified better functioning at baseline, comorbid personality disorder, somatic comorbidity and life events during treatment as determinants of a worse outcome. Conclusions: Functioning of older persons with psychiatric problems largely improves after treatment in routine mental health care.
Space-time overlays for convolutionally coded systems

We consider the design of space-time overlays to upgrade single-antenna wireless communication systems to accommodate multiple transmit antennas efficiently. We define the overlay constraint such that the signal transmitted from the first antenna in the upgraded system is the same as that in the single-antenna system. The signals transmitted from the remaining antennas are designed according to space-time coding principles to achieve full spatial diversity in quasi-static flat fading channels. For both binary phase-shift keying (BPSK) and quaternary phase-shift keying modulation systems, we develop an algebraic design framework that exploits the structure of existing single-dimensional convolutional codes in designing overlays that achieve full spatial diversity with minimum additional decoding complexity at the receiver. We also investigate a concatenated coding approach for a BPSK overlay design in which the inner code is an orthogonal block code. This approach is shown to yield near optimal asymptotic performance for quasi-static fading channels. We conclude by offering a brief discussion outlining the extension of the proposed techniques to time-varying block fading channels.
B7-H3 silencing by RNAi inhibits tumor progression and enhances chemosensitivity in U937 cells

Background The role of B7-H3 in acute monocytic leukemia U937 cells has not been thoroughly investigated. Materials and methods B7-H3 knockdown in the U937 cell line was performed using small hairpin (sh)RNA lentivirus transduction. The effects on cell proliferation, cycle, migration, and invasion were investigated by Cell Counting Kit-8 assay, methyl cellulose colony-forming assay, propidium iodide staining, and Transwell assays in vitro. Changes in cell growth inhibition and apoptosis, when combined with chemotherapy drugs, were determined using the Cell Counting Kit-8 and Annexin V-FITC/PI assays. U937 xenograft models were used to assess the effects of B7-H3 on tumorigenicity and the therapeutic effect of B7-H3 knockdown in combination with chemotherapy drugs in vivo. Results Downregulation of B7-H3 significantly decreased U937 cell growth and colony-forming ability. The mean inhibition rate of tumor growth with B7-H3 knockdown was 59.4%, and the expression of both Ki-67 and PCNA in xenografts was significantly reduced. After B7-H3 silencing, the U937 cell cycle was arrested at the G0/G1 phase. The cell migration rate of B7-H3 knockdown cells was reduced more than fivefold, and invasion capacity decreased by 86.7%. B7-H3 RNAi profoundly increased the antitumor effect of chemotherapy in vitro and in vivo. On day 19, inhibition rates of tumor growth in B7-H3 shRNA combined with idarubicin, cytarabine, and idarubicin plus cytarabine were 70.5%, 80.0%, and 90.0%, respectively (P=0.006, P=0.004, and P=0.016, respectively). Conclusion B7-H3 may promote U937 cell progression, and shRNA targeting B7-H3 significantly enhances sensitivity to chemotherapeutic drugs. These results may provide new insight into the function of B7-H3 and a promising therapeutic approach targeting B7-H3 in acute monocytic leukemia.
Please Scroll down for Article Communications in Algebra Θ*-relation on Hypermodules and Fundamental Modules over Commutative Fundamental Rings * -relation on Hypermodules and Fundamental Modules over Commutative Fundamental Rings

This article may be used for research, teaching and private study purposes. Any substantial or systematic reproduction, redistribution , reselling , loan or sub-licensing, systematic supply or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this material. The main tools in the theory of hyperstructues are the fundamental relations. The fundamental relation on a hypermodule over a hyperring was already introduced by Vougiouklis. The fundamental relation on a hypermodule over a hyperring is defined as the smallest equivalence relation so that the quotient would be the module over a ring. Note that generally the commutativity with respect to both sum in the (fundemental) module and product in the (fundamental) ring are not assumed. In this article we introduce a new strongly regular equivalence relation on hypermodules so that the quotient is module (with abelin group) over a commutative ring. Also we state the conditions that is equivalent with the transitivity of this relation and finally we characterize the complete hypermodules over hyperrings.
Mutation in SUMO E3 ligase, SIZ1, Disrupts the Mature Female Gametophyte in Arabidopsis

Female gametophyte is the multicellular haploid structure that can produce embryo and endosperm after fertilization, which has become an attractive model system for investigating molecular mechanisms in nuclei migration, cell specification, cell-to-cell communication and many other processes. Previous reports found that the small ubiquitin-like modifier (SUMO) E3 ligase, SIZ1, participated in many processes depending on particular target substrates and suppression of salicylic acid (SA) accumulation. Here, we report that SIZ1 mediates the reproductive process. SIZ1 showed enhanced expression in female organs, but was not detected in the anther or pollen. A defect in the siz1-2 maternal source resulted in reduced seed-set regardless of high SA concentration within the plant. Moreover, aniline blue staining and scanning electron microscopy revealed that funicular and micropylar pollen tube guidance was arrested in siz1-2 plants. Some of the embryo sacs of ovules in siz1-2 were also disrupted quickly after stage FG7. There was no significant affects of the siz1-2 mutation on expression of genes involved in female gametophyte development- or pollen tube guidance in ovaries. Together, our results suggest that SIZ1 sustains the stability and normal function of the mature female gametophyte which is necessary for pollen tube guidance.
The effect of fibroids without cavity involvement on ART outcomes independent of ovarian age.

BACKGROUND The effect of fibroids that do not distort the endometrial cavity on pregnancy rate (PR) and implantation rate (IR) is controversial. Use of oocyte donor-derived embryos offers an ideal patient population to study the effect of fibroids in patients utilizing assisted reproductive technologies (ARTs). METHODS We conducted a retrospective cohort study of patients undergoing oocyte donor recipient (ODR) IVF cycles at two tertiary care fertility centres. We examined medical records for the presence of non-cavity-distorting fibroids and evaluated subsequent PR and IR. RESULTS Three hundred and sixty-nine patients, 94 with fibroids, underwent oocyte donor recipient transfer cycles with fresh embryos. There was no statistical difference in IR (36 versus 38%) or clinical PR (47 versus 54%) between patients with or without fibroids. Neither the location (subserosal versus intramural) and the presence of multiple myomas nor the size of the myomas affected outcomes. Fibroids were more likely to be present in patients with increasing recipient age. CONCLUSIONS Clinical PR and IR are not affected by the presence of non-cavity-distorting leiomyomata. This evidence does not support myomectomy before ART in patients with asymptomatic fibroids that do not significantly distort the endometrial cavity or cause abnormal uterine bleeding.
Import Price Elasticities: Reconsidering the Evidence

Recent economic geography and trade empirical studies based on monopolistic competition suggest high levels of trade price elasticities (between 3 and 11). However, price elasticity estimations in trade equations using unit values as price proxies usually lead to lower values of around unity. We show that those inconclusive results may be due to some misspecification in these equations as well as measurement errors in prices. When suitable instrumental variables are used, within a panel of industrialized countries, we obtain high price elasticities, the majority ranging from 1 to 13. The highest estimates correspond to industries producing homogeneous goods.
Battling dragons : issues and controversy in children's literature

Here you'll find a collage of distinguished voices from around the world, offering their own perspectives and experiences with difficult issues: censorship, violence, raw images in picture books, depictions of minorities, gender issues, political correctness, ethical heroes, and more. You'll hear from some of the best-regarded and controversial authors writing for and about children today in essays that are bound to provoke, challenge, move, and perhaps even outrage you. South African author Beverly Naidoo talks about censorship and apartheid. Allan Baillie discusses his choice to write about Pol Pot's reign of terror. Brian Jacques reflects on his own childhood amidst the violence and poverty of Liverpool. Judith Gilliland reveals her motivation for depicting the gritty lives of children in Cairo and Lebanon. Charlotte Huck examines reactions among animal rights groups to her "Princess Furball. " You'll also hear from parents, teachers, librarians, academicians, illustrators, booksellers, and self-appointed censors. And you'll hear from children themselves. Given the large gap in texts for the serious study of children's books, these are voices no one concerned with quality children's literature can afford to ignore.
Optimism Development Across Adulthood and Associations With Positive and Negative Life Events

Numerous studies have demonstrated long-term benefits of optimism for physical and mental health. However, little research has examined how optimism develops across the life span and how it is shaped by positive and negative life experiences. In this study, we examined the normative trajectory of optimism development from ages 26 to 71 in a longitudinal sample (N = 1,169) of Mexican-origin couples assessed 4 times across 7 years. Latent growth curve analyses indicated that optimism increased throughout early and middle adulthood before plateauing at age 55, with significant individual differences in change. Furthermore, the experience of positive events was associated with optimism development across adulthood, but negative life events were not associated with development. Men and women developed similarly in optimism, while U.S.-born participants developed differently from Mexican-born participants. We discuss how these findings inform our understanding of optimism as a dynamic, adaptive construct.
Computational Investigation of Asymmetric Coplanar Waveguides Using Neural Networks : A Microwave Engineering Exercise

In order to compute the characteristic impedance and the relative effective dielectric constant of an asymmetric coplanar waveguide with infinite or finite dielectric thickness, the use of artificial neural networks is valuable. The method of neural computing presented in this paper uses only one neural model for both parameters, for this specific waveguide type. The BFGS quasi-Newton back-propagation algorithm was used to train the developed neural network. Numerical results are given for several configurations along with comparisons with previously published data.
Enhancements to the multiple sleep latency test

Introduction The utility of multiple sleep latency tests (MSLTs) is limited to determining sleep onset latency (SOL) and rapid eye movement sleep latency. The odds ratio product (ORP) is a continuous index of sleep depth with values of 0, 1.0, and 2.5 reflecting very deep sleep, light sleep, and full wakefulness, respectively. We determined the time course of sleep depth during MSLT naps expecting that this would enhance the test’s clinical utility. Methods Thirty MSLTs (150 naps) were performed for excessive somnolence. Patients indicated whether they slept (yes/no) after each nap. SOL was scored by two experienced technologists. Time course of ORP was determined with a commercial system. We determined ORP at SOL (ORPSOL), times ORP decreased <2.0, <1.5, <1.0 and <0.5 during the entire nap duration, and the integral of decrease in ORP over nap duration (ΔORPINT). Results SOL occurred almost invariably when ORP was between 1.0 and 2.0. Of 47 naps (21 patients) with SOL <5 minutes, ORP decreased <1.0 (light sleep) in <5 minutes in only 13 naps (nine patients) and <0.5 (deep sleep) in only two naps in one patient. The relation between ORPINT and frequency of sleep perception was well defined, allowing determination of a threshold for sleep perception. This threshold ranged widely (5–50 ΔORP*epoch). Conclusion As currently identified, SOL reflects transition into a highly unstable state between wakefulness and sleep. Reporting the times of attaining different sleep depths may help better identify patients at high risk of vigilance loss. Furthermore, an ORPSOL outside the range 1.0–2.0 can help identify scoring errors.
An Unexpected Recurrent Transmission of Rift Valley Fever Virus in Cattle in a Temperate and Mountainous Area of Madagascar

Rift Valley fever is an acute, zoonotic viral disease of domestic ruminants, caused by a phlebovirus (Bunyaviridae family). A large outbreak occurred in Madagascar in 2008–2009. The goal of the present study was to evaluate the point prevalence of antibodies against Rift Valley Fever Virus (RVFV) in cattle in the Anjozorobe district, located in the wet and temperate highland region of Madagascar and yet heavily affected by the disease, and analyse environmental and trade factors potentially linked to RVFV transmission. A serological study was performed in 2009 in 894 bovines. For each bovine, the following variables were recorded: age, location of the night pen, minimum distance from the pen to the nearest water point and the forest, nearest water point type, and herd replacement practices. The serological data were analyzed using a generalized linear mixed model. The overall anti-RVFV IgG seroprevalence rate was 28% [CI95% 25–31]. Age was statistically linked to prevalence (p = 10−4), being consistent with a recurrent RVFV circulation. Distance from the night pen to the nearest water point was a protective factor (p = 5.10−3), which would be compatible with a substantial part of the virus transmission being carried out by nocturnal mosquito vectors. However, water point type did not influence the risk of infection: several mosquito species are probably involved. Cattle belonging to owners who purchase animals to renew the herd were significantly more likely to have seroconverted than others (p = 0.04): cattle trade may contribute to the introduction of the virus in this area. The minimum distance of the night pen to the forest was not linked to the prevalence. This is the first evidence of a recurrent transmission of RVFV in such an ecosystem that associates a wet, temperate climate, high altitude, paddy fields, and vicinity to a dense rain forest. Persistence mechanisms need to be further investigated.