Miracle-dz/UniFAR-FTUs huggingface dataset:
The Odd Tango of the Islamic Right and Kurdish Left in Turkey: A Peripheral Alliance to Redesign the Centre?

‘’ The Justice and Development Party (AKP) government’s ‘Kurdish opening’ in the summer of 2009 came as a surprise to many observers of Turkish politics. It was startling that the neo-Islamist AKP, already at odds with the nationalist elements in the state establishment, risked further alienation for the sake of expanding Kurdish rights. After all, pro-Kurdish groups have been traditionally aligned with leftist parties, and the agenda that the AKP pursued since it came to power in 2003 could be best described as ultra-capitalist. Thus, dominant perspectives typically viewed Kurdish and Islamist movements as distinct groups that are discontented with different aspects of Turkish nationalism, namely unitarianism and secularism, and attacking the state establishment from the left and the right, respectively. In contrast to popular approaches that focus on the religious and ethnic fault lines in Turkish society and consider Islamist and Kurdish movements as separate contentious movements, this article focuses on their common ground. This comparative perspective highlights the deeper problems of urban elitism and authoritarianism in Turkey which can cut across religious or ethnic cleavages. Demonstrating the proximity of the voters and the electoral shifts between these two ostensibly different parties, more specifically the neo-Islamist AKP and the leftist and pro-Kurdish Democratic Society Party (DTP), this article suggests that the strong grassroots support for Islamist and pro-Kurdish parties does not necessarily indicate broad support for an Islamic or Kurdish state. Individuals also turn to these parties as an outcry against urban elitism and the political, economic, and cultural isolation and oppression of opposition groups. Islamist and Kurdish parties are most popular among actors from provincial backgrounds (including a wide range of social groups from shantytown dwellers to provincial petite bourgeoisie) who are frustrated with state authoritarianism and the domination of urban elites in political, cultural, and economic realms who deny equal status to new economic and political actors. In this respect, the proximity and shared constituency of the Islamic right and Kurdish left represents a strategic (and mainly provincial) alliance to penetrate central politics. The electoral switches between these two parties suggest that both constituencies prioritize destabilizing the old, authoritarian, and urban-centric state Middle Eastern Studies, Vol. 48, No. 2, 287–302, March 2012
In vitro antioxidant activity of Bombax malabaricum flower extracts

Context: Bombax malabaricum DC. (Bombacaceae) is a traditional Chinese herbal medicine used for the treatment of inflammatory conditions, diarrhea, fever, chronic inflammation, catarrhal affection, and as a diuretic. However, little information is available about its antioxidative activity. Objective: Water, 50% ethanol, and 80% acetone extracts from flowers of B. malabaricum were investigated for their in vitro antioxidant activity in this article for the first time. Then the relationships between antioxidant activity measured by different methods and total phenolic content (TPC) and total flavonoid content (TFC) were established. Materials and methods: The antioxidant activities of extracts from B. malabaricum flower were investigated including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, oxygen radical absorbance capacity (ORAC), reducing power, and inhibition on phosphatidylcholine liposome peroxidation. Results: Results showed that all the extracts possessed remarkable antioxidant capacity compared with ascorbic or gallic acids. Total antioxidant activities evaluated by ORAC assay of different extracts ranged from 700.03 to 1482.46 μmol Trolox equivalents/g. The highest TPC of 130.38 mg gallic acid equivalents (GAE)/g was observed in 80% acetone extract, whereas the lowest TPC of 57.09 mg GAE/g was obtained in the water extract. Furthermore, TFC exhibited significant (P < 0.05) positive correlations with DPPH radical-scavenging activity, ORAC, and reducing power. Discussion and conclusion: These findings demonstrate that the flowers of B. malabaricum have excellent antioxidant activities and thus might be a potential source of natural antioxidants.
Models of Emotion Skills and Social Competence in the Head Start Classroom

Research Findings: Fostering the social competence of at-risk preschoolers would be facilitated by knowing which of children's emotion skills are most salient to social outcomes. We examined the emotion skills and social competence of 44 children enrolled in a Head Start program. Emotion skills were examined in terms of children's emotional lability and emotion regulation, whereas social competence was measured in terms of three aspects of preschoolers' social relationships: social skills, student–teacher relationships, and peer likeability. Although emotion regulation emerged as an important predictor for social skills and positive relationships with teachers, emotional lability was a significant predictor of student–teacher conflict and peer likeability. In fact, emotional lability mediated the relation between student–teacher conflict and peer likeability. Practice or Policy: The findings are discussed in terms of the complex associations between children's emotion skills and early social relationships.
Neurophenotypes in Airway Diseases. Insights from Translational Cough Studies.

RATIONALE Most airway diseases, including chronic obstructive pulmonary disease (COPD), are associated with excessive coughing. The extent to which this may be a consequence of increased activation of vagal afferents by pathology in the airways (e.g., inflammatory mediators, excessive mucus) or an altered neuronal phenotype is unknown. Understanding whether respiratory diseases are associated with dysfunction of airway sensory nerves has the potential to identify novel therapeutic targets. OBJECTIVES To assess the changes in cough responses to a range of inhaled irritants in COPD and model these in animals to investigate the underlying mechanisms. METHODS Cough responses to inhaled stimuli in patients with COPD, healthy smokers, refractory chronic cough, asthma, and healthy volunteers were assessed and compared with vagus/airway nerve and cough responses in a cigarette smoke (CS) exposure guinea pig model. MEASUREMENTS AND MAIN RESULTS Patients with COPD had heightened cough responses to capsaicin but reduced responses to prostaglandin E2 compared with healthy volunteers. Furthermore, the different patient groups all exhibited different patterns of modulation of cough responses. Consistent with these findings, capsaicin caused a greater number of coughs in CS-exposed guinea pigs than in control animals; similar increased responses were observed in ex vivo vagus nerve and neuron cell bodies in the vagal ganglia. However, responses to prostaglandin E2 were decreased by CS exposure. CONCLUSIONS CS exposure is capable of inducing responses consistent with phenotypic switching in airway sensory nerves comparable with the cough responses observed in patients with COPD. Moreover, the differing profiles of cough responses support the concept of disease-specific neurophenotypes in airway disease. Clinical trial registered with www.clinicaltrials. gov (NCT 01297790).
Clinical Supervision: Special Methods for the Supervision of Teachers, 2nd Ed. By Robert Goldhammer, Robert H. Anderson, and Robert J. Kajewski. New York: Holt, Rinehart and Winston, 1980

Drawing heavily on the concepts, strategies, and procedures introduced by Goldhammer in his first edition, this second edition provides detailed explanations of clinical supervision, bringing its workings into clearer focus. Clinical supervision is a timely concept filled with potential for improving instruction in public schools by determining teaching effectiveness. Supervision emanates from the central offices; assistant superintendents or supervisors for instruction and curriculum
CCp5A Protein from Toxoplasma gondii as a Serological Marker of Oocyst-driven Infections in Humans and Domestic Animals

Considering that the current immunoassays are not able to distinguish the infective forms that cause Toxoplasma gondii infection, the present study was carried out to evaluate the reactivity of two recombinant proteins (CCp5A and OWP1) from oocyst/sporozoite, in order to differentiate infections occurring by ingestion of oocysts or tissue cysts. The reactivity of the recombinant proteins was assessed against panels of serum samples from animals (chickens, pigs, and mice) that were naturally or experimentally infected by different infective stages of the parasite. Also, we tested sera from humans who have been infected by oocysts during a well-characterized toxoplasmosis outbreak, as well as sera from pregnant women tested IgM+/IgG+ for T. gondii, which source of infection was unknown. Only the sporozoite-specific CCp5A protein was able to differentiate the parasite stage that infected chickens, pigs and mice, with specific reactivity for oocyst-infected animals. Furthermore, the CCp5A showed preferential reactivity for recent infection by oocyst/sporozoite in pigs and mice. In humans, CCp5A showed higher reactivity with serum samples from the outbreak, compared with serum from pregnant women. Altogether, these findings demonstrate the usefulness of the CCp5A protein as a new tool to identify the parasite stage of T. gondii infection, allowing its application for diagnosis and epidemiological investigations in animals and humans. The identification of parasite infective stage can help to design effective strategies to minimize severe complications in immunocompromised people and, particularly, in pregnant women to prevent congenital infection.
Assessment based on exercise work and multiple-choice tests

Higher education institutions in Norway have implemented reform as part of the Bologna Agreement. The reform also aims to follow up students more closely and to change the way in which they learn by increasing the amount of formative assessment, including grading. This paper presents a case study of a first-year methodology course in geography, in which students' performance in exercise work and tests based on multiple-choice questions was graded. Multiple-choice tests were used to increase the level of reflection during exercise work and to encourage students to read continuously throughout the semester.
Management attitudes and technology adoption in long-term care facilities.

PURPOSE The purpose of this paper is to explore the attitudes of nursing home administrators and key managerial staff toward health information technology (health IT). DESIGN/METHODOLOGY/APPROACH This research is exploratory in nature, and applies qualitative case-study methodology to further understand health IT adoption by nursing homes through multiple in-depth semi-structured interviews of management, and direct observations of employee behavior at each participating facility. A modified Technology Acceptance Model is used to examine the attitudes and perceptions of administrators. FINDINGS This study finds that there are differences in the level of health IT adoption by nursing homes. While some administrators are aware of health IT and are implementing or updating their IT systems in a gradual but haphazard manner, others exhibited a lack of interest in implementing change. Overall, there is a lack of systematic planning and decision-making toward health IT adoption. Adoption is not evidence-based, instead driven primarily by real and perceived regulatory requirements combined with a lack of information about, or consideration of, the real costs and benefits of implementing health IT. RESEARCH LIMITATIONS/IMPLICATIONS Including six in-depth case studies, the sample for this study is small for generalizing the findings. Yet, it contributes to the literature on the slow process of health IT adoption by nursing homes. Moreover, the findings provide guidelines for future research. PRACTICAL IMPLICATIONS This study demonstrates that nursing home administrators must systematically plan the adoption of health IT, and such decision making should be evidenced-based and participatory so that employees can voice their opinions that could prevent future resistance. ORIGINALITY/VALUE This study is original and advances knowledge on the reasons for the slow adoption of health IT in nursing homes. It finds that lack of adequate information regarding the utility and benefits of health IT in management adoption decisions can result in haphazard implementation or no adoption at all. This finding has significant value for policy makers' practitioners for improving accessibility of information regarding the use of health IT in nursing homes that could address the health IT adoption challenge in this industry.
‘Race’, Employment and Equal Opportunities: Towards a Political Economy and an Agenda for the 1990s

This paper attempts to provide a broad overview of the recent history of equal opportunities, particularly of work-place policies and programmes directed towards ethnic minorities. It identifies three main stages in the recent history of equal opportunities at the work-place and seeks to connect these with an analysis of the economic arrangements and dominant political philosophies characteristic of each phase. The paper concludes by noting that there is currently a widespread view that equal opportunities policies represents a happy coincidence of principle and expediency for firms in the 1990s. It suggests that whilst a number of trends with the potential to realise this promise can be discerned, other outcomes are possible. Writing in mid-1992, it remains to be seen whether the new rhetoric of citizenship and business efficiency can secure both the continuing commitment of those with the power to make changes and the enduring support of the disadvantaged.
Confirmatory factor analysis (CFA) of USM Emotional Quotient Inventory (USMEQ-i) among medical degree program applicants in Universiti Sains Malaysia (USM)

Introduction : Emotional intelligence (EI) is deemed an important aspect of being good medical doctors. Universiti Sains Malaysia (USM) Emotional Quotient Inventory (USMEQ-i) is an EI inventory in Malay language developed primarily as medical student selection tool in USM. Although it was already validated by exploratory factor analysis (EFA), EFA is considered insufficient evidence of construct validity, thus confirmatory factor analysis (CFA) was conducted. Objectives : To determine measurement model validity and construct validity of USMEQ-i among medical degree program applicants in USM by CFA. Methods : USMEQ-i data file for medical degree program applicants in USM for year 2010/2011 and 2011/2012 academic sessions were obtained from Medical Education Department in USM. A random sample of 512 cases was drawn from the data file. Of the sample, only 453 cases were valid study sample after preliminary data screening and assumption checking. CFA was conducted on the sample using maximum likelihood (ML) estimation with bootstrapping technique due to violation of multivariate normality assumption. USMEQ-i measurement model was proposed as a second-order EI factor with seven first-order factors of EI and a Faking Index (FI) factor, with correlation between second-order EI factor and FI factor. Results : The proposed model could not be fit into the study sample data. EI factors and FI factor had to be analyzed separately due to non-positive definite problem. After modifications to the model, CFA of EI factors were suggestive of two-factor model instead of the proposed seven-factor model. Consciousness, Maturity and Control (CoMaCt). CFA of FI factor maintained one-factor model and also valid in term of construct. Conclusion : The modified USMEQ-i, which consisted of separate EI and FI models, was proven to have valid measurement models and reliable constructs. It is considered to be suitable for use among applicants to medical degree program in USM. However, its use as medical student selection tool may require further research, especially how predictive USMEQ-i scores with real performance of medical students, generalizability of the inventory and its stability over time.
Capacity of a Mobile Multiple-Antenna Communication Link in Rayleigh Flat Fading

We analyze a mobile wireless link comprising M transmitter and N receiver antennas operating in a Rayleigh flat-fading environment. The propagation coefficients between pairs of transmitter and receiver antennas are statistically independent and unknown; they remain constant for a coherence interval of T symbol periods, after which they change to new independent values which they maintain for another T symbol periods, and so on. Computing the link capacity, associated with channel coding over multiple fading intervals, requires an optimization over the joint density of T/spl middot/M complex transmitted signals. We prove that there is no point in making the number of transmitter antennas greater than the length of the coherence interval: the capacity for M>T is equal to the capacity for M=T. Capacity is achieved when the T/spl times/M transmitted signal matrix is equal to the product of two statistically independent matrices: a T/spl times/T isotropically distributed unitary matrix times a certain T/spl times/M random matrix that is diagonal, real, and nonnegative. This result enables us to determine capacity for many interesting cases. We conclude that, for a fixed number of antennas, as the length of the coherence interval increases, the capacity approaches the capacity obtained as if the receiver knew the propagation coefficients.
Detection and Classification of Pole-like Objects from Mobile Laser Scanning Data of Urban Environments

The Mobile Laser Scanning (MLS) system can acquire point clouds of urban environments including roads, buildings, trees, lamp posts etc. and enables effective mapping of them. With the spread of the MLS system, the demands for the management of roads and facilities using MLS point clouds have increased. Especially, pole-like objects (PLOs) such as lamp posts, utility poles, street signs etc. are strongly expected to be managed efficiently. We propose a method for detecting PLOs from MLS point clouds and classifying them into three classes: utility poles, lamp posts, and street signs. Our detection method is based on the feature extraction using point classification by Principal Component Analysis (PCA). On the other hand, our classification method is based on not only shape features of the PLOs, but also context features which are derived from the surrounding PLOs distributions. In order to evaluate the accuracy of PLOs detection and classification through our method, we applied our method to MLS point clouds of urban environments.
Phenotyping and Genotyping Characterization of Proteus vulgaris After Biofield Treatment

Proteus vulgaris (P. vulgaris) is widespread in nature, mainly found in flora of human gastrointestinal tract. The current study was attempted to investigate the effects of Mr. Trivedi’s biofield treatment on lyophilized as well as revived state of P. vulgaris for antimicrobial susceptibility pattern, biochemical characteristics, and biotype. P. vulgaris cells were procured from Micro BioLogics Inc., USA, in sealed pack bearing the American Type Culture Collection (ATCC 33420) number and stored according to the recommended storage protocol until needed for experiments. Lyophilized vial of ATCC strain of P. vulgaris were divided in two parts, Gr. I: control and Gr. II: treatment. Group II was further subdivided into two parts, Gr. IIA and Gr. IIB. Gr. IIA was analysed on day 10. Gr. IIB was stored and analysed on day 143. After retreatment on day 143, the sample was divided into three separate tubes. First, second and third tubes were analysed on day 5, 10 and 15 respectively. All experimental parameters were studied using automated Micro Scan Walk-Away® system. The 16S rDNA sequencing of lyophilized treated sample was carried out to correlate the phylogenetic relationship of P. vulgaris with other bacterial species after treatment. The antimicrobial susceptibility and minimum inhibitory concentration showed 10.71% and 15.63% alteration respectively in treated cells of P. vulgaris as compared to control. It was observed that few biochemical reactions (6%) were altered in the treated groups with respect to control. Moreover, biotype number was substantially changed in treated cells, Gr. IIA (62060406, Proteus penneri) on day 10 as compared to control (62070406; Proteus vulgaris). 16S rDNA analysis showed that the identified sample in this experiment was Proteus vulgaris after biofield treatment. However, the nearest homolog genus-species was found to be Proteus hauseri. The results suggested that biofield treatment has impact on P. vulgaris in lyophilized as well as revived state.
Genetic analyses of isolated high‐grade pancreatic intraepithelial neoplasia (HG‐PanIN) reveal paucity of alterations in TP53 and SMAD4

High‐grade pancreatic intraepithelial neoplasia (HG‐PanIN) is the major precursor of pancreatic ductal adenocarcinoma (PDAC) and is an ideal target for early detection. To characterize pure HG‐PanIN, we analysed 23 isolated HG‐PanIN lesions occurring in the absence of PDAC. Whole‐exome sequencing of five of these HG‐PanIN lesions revealed a median of 33 somatic mutations per lesion, with a total of 318 mutated genes. Targeted next‐generation sequencing of 17 HG‐PanIN lesions identified KRAS mutations in 94% of the lesions. CDKN2A alterations occurred in six HG‐PanIN lesions, and RNF43 alterations in five. Mutations in TP53, GNAS, ARID1A, PIK3CA, and TGFBR2 were limited to one or two HG‐PanINs. No non‐synonymous mutations in SMAD4 were detected. Immunohistochemistry for p53 and SMAD4 proteins in 18 HG‐PanINs confirmed the paucity of alterations in these genes, with aberrant p53 labelling noted only in three lesions, two of which were found to be wild type in sequencing analyses. Sixteen adjacent LG‐PanIN lesions from ten patients were also sequenced using targeted sequencing. LG‐PanIN harboured KRAS mutations in 94% of the lesions; mutations in CDKN2A, TP53, and SMAD4 were not identified. These results suggest that inactivation of TP53 and SMAD4 are late genetic alterations, predominantly occurring in invasive PDAC. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Hepatitis B Virus X Protein via the p38MAPK Pathway Induces E2F1 Release and ATR Kinase Activation Mediating p53 Apoptosis*

Hepatitis B virus (HBV) X protein (pX) is implicated in hepatocellular carcinoma (HCC) pathogenesis by an unknown mechanism. Deletions or mutations of genes involved in the p53 pathway are often associated with HBV-mediated HCC, indicating rescue from p53 apoptosis is a likely mechanism in HBV-HCC pathogenesis. Herein, we determined the mechanism by which pX sensitizes hepatocytes to p53-mediated apoptosis. Although it is well established that the Rb/E2F/ARF pathway stabilizes p53, and the DNA damage-activated ATM/ATR kinases activate p53, the mechanism that coordinates these two pathways has not been determined. We demonstrate that the p38MAPK pathway activated by pX serves this role in p53 apoptosis. Specifically, the activated p38MAPK pathway stabilizes p53 via E2F1-mediated ARF expression, and also activates the transcriptional function of p53 by activating ATR. Knockdown of p53, E2F1, ATR, or p38MAPKα abrogates pX-mediated apoptosis, demonstrating that E2F1, ATR, and p38MAPKα are all essential in p53 apoptosis in response to pX. Specifically, in response to pX expression, the p38MAPK pathway activates Cdk4 and Cdk2, leading to phosphorylation of Rb, release of E2F1, and transcription of ARF. The p38MAPK pathway also activates ATR, leading to phosphorylation of p53 on Ser-18 and Ser-23, transcription of pro-apoptotic genes Bax, Fas, and Noxa, and apoptosis. In conclusion, pX sensitizes hepatocytes to p53 apoptosis via activation of the p38MAPK pathway, which couples p53 stabilization and p53 activation, by E2F1 induction and ATR activation, respectively.