Miracle-dz/UniFAR-FTUs huggingface dataset:
Turbidity threshold sampling for suspended sediment load estimation

Abstract: The paper discusses an automated procedure for measuring turbidity and sampling suspended sediment. The basic equipment consists of a programmable data logger, an in situ turbidimeter, a pumping sampler, and a stage-measuring device. The data logger program employs turbidity to govern sample collection during each transport event. Mounting configurations and housings for the turbidimeters have been prototyped and tested or deployed at 16 gaging sites in northwestern California. Operational data are presented with examples illustrating storm load estimation.
A Temporal Perspective on Social Comparisons in Organizations

textabstractIndividuals evaluate their social standing through comparisons with others. These social comparisons affect individuals’ thoughts, feelings, and behavior at the workplace. This dissertation aims to advance our knowledge of the effects of these comparisons by taking a temporal perspective on the social comparison process. Contrary to previous research that looked at social comparisons as a single snapshot in time, this dissertation acknowledges the dynamic nature of social comparisons, in particular, that individuals’ standing may change over time. In three chapters, this dissertation examines how considerations of future status are derived from past relative trajectories and lead to positive and negative interpersonal as well the role of individuals’ goal orientation in their preferences for different temporal and static comparisons.
Electrophysiological Evidence for Different Inhibitory Mechanisms When Stopping or Changing a Planned Response

People are able to adapt their behavior to changing environmental contingencies by rapidly inhibiting or modifying their actions. Response inhibition is often studied in the stop-signal paradigm that requires the suppression of an already prepared motor response. Less is known about situations calling for a change of motor plans such that the prepared response has to be withheld but another has to be executed instead. In the present study, we investigated whether electrophysiological data can provide evidence for distinct inhibitory mechanisms when stopping or changing a response. Participants were instructed to perform in a choice RT task with two classes of embedded critical trials: Stop signals called for the inhibition of any response, whereas change signals required participants to inhibit the prepared response and execute another one instead. Under both conditions, we observed differences in go-stimulus processing, suggesting a faster response preparation in failed compared with successful inhibitions. In contrast to stop-signal trials, changing a response did not elicit the inhibition-related frontal N2 and did not modulate the parietal mu power decrease. The results suggest that compared with changing a response, additional frontal and parietal regions are engaged when having to inhibit a response.
Extensive population decline in the Tasmanian devil predates European settlement and devil facial tumour disease

The Tasmanian devil (Sarcophilus harrisii) was widespread in Australia during the Late Pleistocene but is now endemic to the island of Tasmania. Low genetic diversity combined with the spread of devil facial tumour disease have raised concerns for the species’ long-term survival. Here, we investigate the origin of low genetic diversity by inferring the species' demographic history using temporal sampling with summary statistics, full-likelihood and approximate Bayesian computation methods. Our results show extensive population declines across Tasmania correlating with environmental changes around the last glacial maximum and following unstable climate related to increased ‘El Niño–Southern Oscillation’ activity.
Hepatic HMOX1 Expression Positively Correlates with Bach-1 and miR-122 in Patients with HCV Mono and HIV/HCV Coinfection

Aim To analyze the expression of HMOX1 and miR-122 in liver biopsy samples obtained from HCV mono-and HIV/HCV co-infected patients in relation to selected clinical parameters, histological examination and IL-28B polymorphism as well as to determine whether HMOX1 expression is dependent on Bach-1. Materials and Methods The study group consisted of 90 patients with CHC: 69 with HCV mono and 21 with HIV/HCV co-infection. RT-PCR was used in the analysis of HMOX1, Bach-1 and miR-122 expression in liver biopsy samples and in the assessment of IL-28B single-nucleotide polymorphism C/T (rs12979860) in the blood. Moreover in liver biopsy samples an analysis of HO-1 and Bach-1 protein level by Western Blot was performed. Results HCV mono-infected patients, with lower grading score (G<2) and higher HCV viral load (>600000 IU/mL) demonstrated higher expression of HMOX1. In patients with HIV/HCV co-infection, the expression of HMOX1 was lower in patients with lower lymphocyte CD4 count and higher HIV viral load. IL28B polymorphism did not affect the expression of either HMOX1 or miR-122. Higher HMOX1 expression correlated with higher expression of Bach-1 (Spearman’s ρ = 0.586, p = 0.000001) and miR-122 (Spearman’s ρ = 0.270, p = 0.014059). Conclusions HMOX1 and miR-122 play an important role in the pathogenesis of CHC in HCV mono-and HIV/HCV co-infected patients. Reduced expression of HMOX1 in patients with HIV/HCV co-infection may indicate a worse prognosis in this group. Our results do not support the importance of Bach-1 in repression of HMOX1 in patients with chronic hepatitis C.
A study on the relationship between clinical features with Ki67 expression and eosinophil cells infiltration in oral squamous cell carcinoma

Background: Cell proliferation is one of the most critical factors in metastasis and prognosis of the malignant tumors.Recent investigations show that the eosinophil granolosytes have an important role in developing of malignant tumors. The relation between cell proliferation and eosinophilic infiltration in oral squamous cell carcinoma (OSCS) with prognosis is unclear. The aim of this study was to investigate the relationship between the Ki67 expression and eosinophilic infiltration with the clinical features on OSCC. Methods: This study was cross sectional in which 24 paraffined embeded block of OSCC selected from the Imam Khomeini hospital; cancer institute’s archive. 4 micron sections were prepared and studied for Ki67 antigen immunohistochemically. The labeling index (LI: positive epithelial cells/1000 epithelial cells) of Ki67 positive cells were obtained. In each section eosinophilic cells were counted in 10 fields with 400 (HPF). The relations between the eosinophil cells and Ki67 positive cells counts with clinical features and histopathological differentiation were achived by the linear regression and spirman statistical tests. Results: There were no any significant relationship between gender, histopathological differentiation and the number of eosinophils and Ki67 positive cells counts (p= 0.33 and p=0.73). A significant relationship between lymph node involvement and the number of eosinophils and the Ki67 positive cells counts was found (p=0.04). There was a positive relationship between the number of Ki67 positive cells and the number of eosinophil cells (p= 0.05). Conclusion: A significant relationship between lymph node involvement with eosinophilc cells and Ki67 positive cells counts were exist.
Investigation of Factors That Influence Public Librarians’ Social Media Use for Marketing Purposes: An Adoption of the Technology Acceptance Model and Theory of Planned Behavior

This study aims to explore multiple factors that are associated with social media use by public librarians for marketing purposes. Based on the technology acceptance model and theory of planned behavior, the effects of five factors—usefulness, ease of use, attitude, subjective norms, and behavioral control—on social media use intention were examined. A survey was conducted, and 462 valid responses were collected from public librarians across the United States. The findings revealed that all five factors have a significant impact on librarians’ intention to engage in social media activities for library marketing. Perceived behavioral control factors were the most influential on social media use intention. Both practical and theoretical implications are discussed based on the findings of this study.
Effect of Feeding Melengestrol Acetate, Monensin, and Tylosin on Performance, Carcass Measurements, and Liver Abscesses of Feedlot Heifers

Approximately 4,000 yearling heifers (initial BW = 306 ± 1.9 kg) were randomly allotted into 4 treatment groups to determine the effect of melengestrol acetate (MGA) on feedlot performance and carcass parameters. Treatments included a diet containing monensin (Rumensin) and tylosin (Tylan; RT) fed during the entire feeding period; RT plus MGA (RTM) also fed during the entire feeding period; RT withdrawn 35 d preslaughter (RTwd); and RTM withdrawn 35 d preslaughter (RTMwd). All cattle were implanted at arrival with Revalor-IH and reimplanted with Revalor-200, and were fed a standard feedlot finishing diet (that met or exceeded 1996 NRC requirements) for approximately 150 d. Final BW, ADG, hot carcass weight (HCW), DMI, and percentage of cattle grading Choice were greater (P < 0.05) for RTM than for all other treatments. Withdrawal of MGA (RTMwd) significantly (P < 0.01) decreased ADG, HCW, 12th-rib fat thickness, calculated YG, and percentage of carcasses grading Choice, but significantly increased the percentage of dark-cutting carcasses, LM area, and YG 1, 2, or 3 carcasses compared with RTM. There were no significant differences (except for dressing percentage) between RT and RTwd. Heifers continuously fed MGA increased in ADG, HCW, and carcass quality traits of economic importance compared with other treatments. Withdrawal of MGA, Rumensin, and Tylan 35 d preslaughter adversely affected carcass weight and carcass quality traits of economic importance when compared with a feeding program including MGA, Rumensin, and Tylan.
Response of school personnel to student threat assessment training

School safety has become an important area of concern for school improvement. This study examined the effects of staff training as means of improving school responses to student threats of violence. A multidisciplinary sample of 351 staff from 2 school divisions completed pre-post training surveys as part of a 1-day training program using the Guidelines for Responding to Student Threats of Violence (Cornell & Sheras, 2006). Analysis of pre-post surveys found large changes in staff attitudes toward school safety and violence prevention efforts. There was a substantial decrease in concerns about school homicide and increased awareness of effective violence prevention efforts. There was a drop in support for zero tolerance and profiling approaches, along with increased knowledge of threat assessment principles and concepts. These changes were sustained across school divisions serving a challenging urban population and a more affluent, suburban population. Similar effects were found across all school personnel. These findings demonstrate the viability of training staff in a student threat assessment approach.
Neural Interaction of the Amygdala with the Prefrontal and Temporal Cortices in the Processing of Facial Expressions as Revealed by fMRI

Some involvement of the human amygdala in the processing of facial expressions has been investigated in neuroimaging studies, although the neural mechanisms underlying motivated or emotional behavior in response to facial stimuli are not yet fully understood. We investigated, using functional magnetic resonance imaging (fMRI) and healthy volunteers, how the amygdala interacts with other cortical regions while subjects are judging the sex of faces with negative, positive, or neutral emotion. The data were analyzed by a subtractive method, then, to clarify possible interaction among regions within the brain, several kinds of analysis (i.e., a correlation analysis, a psychophysiological interaction analysis and a structural equation modeling) were performed. Overall, significant activation was observed in the bilateral fusiform gyrus, medial temporal lobe, prefrontal cortex, and the right parietal lobe during the task. The results of subtraction between the conditions showed that the left amygdala, right orbitofrontal cortex, and temporal cortices were predominantly involved in the processing of the negative expressions. The right angular gyrus was involved in the processing of the positive expressions when the negative condition was subtracted from the positive condition. The correlation analysis showed that activity in the left amygdala positively correlated with activity in the left prefrontal cortex under the negative minus neutral subtraction condition. The psychophysiological interaction revealed that the neural responses in the left amygdala and the right prefrontal cortex underwent the condition-specific changes between the negative and positive face conditions. The right amygdaloid activity also had an interactive effect with activity in the right hippocampus and middle temporal gyrus. These results may suggest that the left and right amygdalae play a differential role in effective processing of facial expressions in collaboration with other cortical or subcortical regions, with the left being related with the bilateral prefrontal cortex, and the right with the right temporal lobe.
Knockdown of phosphodiesterase 4D inhibits nasopharyngeal carcinoma proliferation via the epidermal growth factor receptor signaling pathway

Phosphodiesterase 4D (PDE4D) is a subtype of metallohydrolases, and it has been reported that PDE4D functions as a proliferation promoting factor in certain types of cancer, including head and neck cancer. The present study first investigated the function of PDE4D in nasopharyngeal carcinoma (NPC). Western blot analysis was applied to detect PDE4D expression in NPC samples and cells. A lentiviral infection technique was used to stabilize the knockdown of PDE4D, which was subsequently examined in vitro and in vivo. The results showed that PDE4D was overexpressed in the NPC tissues and cells. Knockdown of PDE4D inhibited the growth of CNE2 and 5–8F, inducing cell cycle arrest in the G0/G1 phase in CNE2. These effects could be reversed by epidermal growth factor (EGF) stimulation. Furthermore, knockdown of PDE4D significantly inhibited the phosphorylation of epidermal growth factor receptor (EGFR) and AKT. The results were further validated in an NPC xenograft in nude mice. In conclusion, this study demonstrated that PDE4D may function as a proliferation promoting factor in NPC, by affecting the EGFR/PI3K/AKT signaling pathway. Therefore, the targeting of PDE4D may be a rational strategy in the treatment of NPC.
GROWING RADIAL BASIS FUNCTION

This paper presents and evaluates two algorithms for incrementally constructing Radial Basis Function Networks, a class of neural networks which looks more suitable for adtaptive control applications than the more popular backpropagation networks. The rst algorithm has been derived by a previous method developed by Fritzke, while the second one has been inspired by the CART algorithm developed by Breiman for generation regression trees. Both algorithms proved to work well on a number of tests and exhibit comparable performances. An evaluation on the standard case study of the Mackey-Glass temporal series is reported.
Spitzer SAGE Survey of the Large Magellanic Cloud. II. Evolved Stars and Infrared Color-Magnitude Diagrams

Color-magnitude diagrams (CMDs) are presented for the Spitzer SAGE (Surveying the Agents of a Galaxy's Evolution) survey of the Large Magellanic Cloud (LMC). IRAC and MIPS 24 μm epoch 1 data are presented. These data represent the deepest, widest mid-infrared CMDs of their kind ever produced in the LMC. Combined with the Two Micron All Sky Survey, the diagrams are used to delineate the evolved stellar populations in the LMC, as well as Galactic foreground and extragalactic background populations. Some 32,000 evolved stars brighter than the tip of the red giant branch are identified. Of these, approximately 17,500 are classified as oxygen-rich, 7000 as carbon-rich, and another 1200 as "extreme" asymptotic giant branch (AGB) stars. Brighter members of the latter group have been called "obscured" AGB stars in the literature owing to their dusty circumstellar envelopes. A large number (1200) of luminous oxygen-rich AGB stars/M supergiants are also identified. Finally, there is strong evidence from the 24 μm MIPS channel that previously unexplored, lower luminosity oxygen-rich AGB stars contribute significantly to the mass-loss budget of the LMC (1200 such sources are identified).
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts

T-cell immunotherapies are promising options in relapsed/refractory B-precursor acute lymphoblastic leukemia (ALL). We investigated the effect of co-signaling molecules on T-cell attack against leukemia mediated by CD19/CD3-bispecific T-cell engager. Primary CD19+ ALL blasts (n≥10) and physiologic CD19+CD10+ bone marrow precursors were screened for 20 co-signaling molecules. PD-L1, PD-1, LAG-3, CD40, CD86, CD27, CD70 and HVEM revealed different stimulatory and inhibitory profiles of pediatric ALL compared to physiologic cells, with PD-L1 and CD86 as most prominent inhibitory and stimulatory markers. PD-L1 was increased in relapsed ALL patients (n=11) and in ALLs refractory to Blinatumomab (n=5). Exhaustion markers (PD-1, TIM-3) were significantly higher on patients' T cells compared to physiologic controls. T-cell proliferation and effector function was target-cell dependent and correlated to expression of co-signaling molecules. Blockade of inhibitory PD-1-PD-L and CTLA-4-CD80/86 pathways enhanced T-cell function whereas blockade of co-stimulatory CD28-CD80/86 interaction significantly reduced T-cell function. Combination of Blinatumomab and anti-PD-1 antibody was feasible and induced an anti-leukemic in vivo response in a 12-year-old patient with refractory ALL. In conclusion, ALL cells actively regulate T-cell function by expression of co-signaling molecules and modify efficacy of therapeutic T-cell attack against ALL. Inhibitory interactions of leukemia-induced checkpoint molecules can guide future T-cell therapies.
What to say to a skeptical metaphysician: A defense manual for cognitive and behavioral scientists

A wave of recent work in metaphysics seeks to undermine the anti-reductionist, functionalist consensus of the past few decades in cognitive science and philosophy of mind. That consensus apparently legitimated a focus on what systems do, without necessarily and always requiring attention to the details of how systems are constituted. The new metaphysical challenge contends that many states and processes referred to by functionalist cognitive scientists are epiphenomenal. It further contends that the problem lies in functionalism itself, and that, to save the causal significance of mind, it is necessary to re-embrace reductionism. We argue that the prescribed return to reductionism would be disastrous for the cognitive and behavioral sciences, requiring the dismantling of most existing achievements and placing intolerable restrictions on further work. However, this argument fails to answer the metaphysical challenge on its own terms. We meet that challenge by going on to argue that the new metaphysical skepticism about functionalist cognitive science depends on reifying two distinct notions of causality (one primarily scientific, the other metaphysical), then equivocating between them. When the different notions of causality are properly distinguished, it is clear that functionalism is in no serious philosophical trouble, and that we need not choose between reducing minds or finding them causally impotent. The metaphysical challenge to functionalism relies, in particular, on a naïve and inaccurate conception of the practice of physics, and the relationship between physics and metaphysics.
Correction: Hyaluronic Acid Injections Are Associated with Delay of Total Knee Replacement Surgery in Patients with Knee Osteoarthritis: Evidence from a Large U.S. Health Claims Database

1 Department of Rheumatology, University of California Los Angeles, Los Angeles, California, United States of America, 2 North American Business Unit, Seikagaku Corporation, Tokyo, Japan, 3 Department of Medical Affairs, Bioventus LLC, Durham, NC, United States of America, 4 Department of Orthopaedics, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
Effect of timing of umbilical cord clamp on newborns' iron status and its relation to delivery type.

OBJECTIVE This study was conducted to evaluate the hematological effects of umbilical cord clamp timing and delivery type in term infants 48 hours after birth in Imam Hossein Hospital, Tehran, Iran. METHOD From Oct 2007 - March 2008, 100 mother-infant eligible pairs were selected and divided by cord clamp timing (< or =15 s and >15 s) for hematologic value determination between the two groups. Data analysis was performed with SPSS for Windows statistical package (version 13). RESULTS Maternal hematological status was assessed upon admission to the delivery room. A total of 100 mother-infant pairs were divided into two groups: delayed cord clamp time within 15 s (n=70) or early cord clamp time [15 s after delivery (n=30)]. The groups had similar demographic and biomedical characteristics at baseline. Forty-eight hours after delivery the mean infant hemoglobin (Hgb; 16.08 gm/dL vs. 14.5 gm/dL; P<0.001) and hematocrit (Hct 47.6 vs. 42.8; P<0.001) levels were significantly higher in the delayed clamping group. There was no significant difference in ferritin levels (214.7 vs. 173.6 ng/dL; P=0.08). Fifty infants were born vaginally and 50 were delivered by cesarean section. Infants delivered vaginally had significantly more delayed cord clamp times (>15 s; P<0.001). CONCLUSION Delaying cord clamping increases the red cell mass in term infants. It is a safe, simple and low cost delivery procedure that should be incorporated in integrated programs that are aimed at reducing iron deficiency anemia in infants in developing countries. Vaginal delivery facilitates this action.
Feature selection for Lidar-based gait recognition

In this paper, we present a performance analysis of various descriptors suited to human gait analysis in Rotating Multi-Beam (RMB) Lidar measurement sequences. The gait descriptors for training and recognition are observed and extracted in realistic outdoor surveillance scenarios, where multiple pedestrians walk concurrently in the field of interest, their trajectories often intersect, while occlusions or background noise may affects the observation. For the Lidar scenes, we compared the modifications of five approaches proposed originally for optical cameras or Kinect measurements. Our results confirmed that efficient person re-identification can be achieved using a single Lidar sensor, even if it produces sparse point clouds.
After the cultural turn: For a textural sociology

This article proposes the social sciences consider texture – rather than text − as the important legacy of the ‘cultural turn’ in the social sciences. The article considers texture in the literal sense of surface-patterns, as well as texture as a metaphor for the ‘dynamic’ and hard-to-capture qualities of social life. The article draws on the philosopher Stephen C. Pepper and the anthropologist Tim Ingold, the ‘practice turn’ in organizational studies and recent developments in geography and cultural research to map out different textural frameworks. While sociologists have lagged behind their counterparts in other fields in embracing a textural sensibility, the article considers the writings of Georg Simmel and the Yale School of Cultural Sociology as prominent exceptions to that rule. The article concludes by encouraging sociologists to consider the textural as a way into a ‘theoretical’ – as against a purely ‘methodological’ conception – of the qualitative.