Miracle-dz/UniFAR-FTUs huggingface dataset:
The tectonic evolution of a critical segment of the Dinarides‐Alps connection: Kinematic and geochronological inferences from the Medvednica Mountains, NE Croatia

The transition zone between the Alps and Dinarides is a key area to investigate kinematic interactions of neighboring orogens with different subduction polarities. A study combining field kinematic and sedimentary data, microstructural observations, thermochronological data (Rb‐Sr and fission track), and regional structures in the area of Medvednica Mountains has revealed a complex polyphase tectonic evolution. We document two novel stages of extensional exhumation. The first stage of extension took place along a Late Cretaceous detachment following the late Early Cretaceous nappe stacking, burial, and greenschist facies metamorphism. Two other shortening events that occurred during the latest Cretaceous‐Oligocene were followed by a second event of extensional exhumation, characterized by asymmetric top‐NE extension during the Miocene. Top‐NW thrusting took place subsequently during the Pliocene inversion of the Pannonian Basin. The Cretaceous nappe burial, Late Cretaceous extension, and the Oligocene(‐Earliest Miocene) contraction are events driven by the Alps evolution. In contrast, the latest Cretaceous‐Eocene deformation reflects phases of Dinaridic contraction. Furthermore, the Miocene extension and subsequent inversion display kinematics similar with observations elsewhere in the Dinarides and Eastern Alps. All these processes demonstrate that the Medvednica Mountains were affected by Alpine phases of deformations to a much higher degree than previously thought. Similarly with what has been observed in other areas of contractional polarity changes, such as the Mediterranean, Black Sea, or New Guinea systems, the respective tectonic events are triggered by rheological weak zones which are critical for localizing the deformation created by both orogens.
System Infrastructure for Mobile-Cloud Convergence

The convergence of mobile computing and cloud computing enables new mobile applications that are both resource-intensive and interactive. For these applications, end-to-end network bandwidth and latency matter greatly when cloud resources are used to augment the computational power and battery life of a mobile device. This dissertation designs and implements a new architectural element called a cloudlet, that arises from the convergence of mobile computing and cloud computing. Cloudlets represent the middle tier of a 3-tier hierarchy, mobile device — cloudlet—cloud, to achieve the right balance between cloud consolidation and network responsiveness. We first present quantitative evidence that shows cloud location can affect the performance of mobile applications and cloud consolidation. We then describe an architectural solution using cloudlets that are a seamless extension of todays cloud computing infrastructure. Finally, we define minimal functionalities that cloudlets must offer above/beyond standard cloud computing, and address corresponding technical challenges.
Impact of Emotional Intelligence on the Job Performance of Employee

Emotional intelligence means understanding one’s own feelings and able to handle those feelings without disturbing themselves. In the same way understanding what others feel and handling relationship effectively motivates one to complete job creatively and perform among their pears. Stress Management is a system that is aimed to reduce stress and/or facilitate the person to cope with stress related instances. This study uses both primary and secondary data. The primary data was collected through questionnaire which is depending on Liker scale. The study confined to the sample size of 100 employees from five software industries namely HP, LENOVO, DELL, HCL & SONY, etc. Finally researcher finds the relationship between the stress management and emotional intelligence. The study is concluded with the suggestion that the Emotional intelligence has ability to quickly reduce stress in the various situations, so we can say that higher level of EI is positively correlated with effectiveness of stress management among software employees.
Automatic Categorization of Japanese Patents based on Surrogate Texts

This paper describes our work at the fifth NTCIR workshop on the subtask of patent classification. We use KNN (K-Nearest Neighbors) as our classifier and the English PAJ (Patent Abstract Japan) as the patent surrogate for classification. Based on the knowledge and experience learned from our previous experiments with other document collections, we leverage on the parameters to achieve above-average performance in an efficient way.
Exhumation and subduction erosion in orogenic wedges: Insights from numerical models

At oceanic margins, syn‐convergent exhumation, subduction erosion, and inter‐plate coupling are intimately related, but ample questions remain concerning their interaction and individual mechanisms. To analyze these interactions for a thick‐skinned, visco‐elastic wedge, we focus on properly modeling stresses, energies, and topographies at the inter‐plate and wedge bounding interfaces using a Coulomb frictional contact algorithm. In this innovative plane‐strain, free surface, Lagrangian finite element model, fault dynamics is modulated by retreating subduction. Subduction is dynamically driven by slab‐pull due to a slab sinking in a semi‐analytic, computationally favorable approximation of three‐dimensional induced mantle flow. Nodal trajectories show that continuous underthrusting of a slab induces a steady state corner flow through forced underplating and subsequent trenchward extrusion due to gravitational spreading. This flow pattern confirms early‐proposed models of syn‐orogenic deep‐seated rock exhumation propelled by coexisting extension and continuous shortening at depth. A distinct reduction in upward flowing material and accompanying decrease of exhumation velocities, to millimeters per year as observed in nature, is induced by a diversion of orogenic wedge material toward the mantle once a subduction channel is formed. The key parameter affecting model evolution and spontaneous formation of a subduction channel is basal friction, which modulates the amount of erosion. However, formation of a subduction channel entrance needs to be ensured through the deformability of the overriding plate, which is influenced by applied pressure at the overriding plate tip and material properties. The down dragging of the overriding plate is sufficient above a threshold inter‐plate shear stress of about 2–7 MPa.
Any impact of blips and low-level viraemia episodes among HIV-infected patients with sustained virological suppression on ART?

OBJECTIVES The objective of this study was to evaluate the prevalence of blips and risk of virological failure (VF) among HIV-infected patients with sustained virological suppression (HIV-RNA <50 copies/mL) on ART. METHODS Newly diagnosed (2004-13) HIV-infected patients with sustained virological suppression on ART (minimum follow-up of 3 months) were identified. Risk of VF was evaluated according to different plasma HIV-RNA quantification values based on the limits of quantification/detection of current commercial assays (20 copies/mL). Kaplan-Meier and Cox proportional hazards models were used to compare the cumulative incidence of VF. RESULTS A total of 565 newly diagnosed HIV-infected patients were identified: 453 started ART and 354 achieved virological suppression. Prevalence of blips (isolated HIV-RNA ranging from 50 to 200 copies/mL) and VF (HIV-RNA ≥50 copies/mL) was 22.7% and 8.8%, respectively (mean follow-up of 42 months). Multivariate analysis identified differences between HIV-RNA values as an independent predictor of VF (P = 0.008); risk of VF was higher for patients with blips [HR 2.500 (95% CI 0.524-11.926)] and for those with at least three consecutive detected, but not quantified, HIV-RNA determinations (HIV-RNA <20 copies/mL) [HR 3.813 (95% CI 0.675-21.535)]. Moreover, only HIV-infected patients with at least three consecutive detected, but not quantified, HIV-RNA determinations showed a higher probability of virological rebound with >200 copies/mL [33.7% at 24 and 60 months versus <5% for other HIV-RNA values; HR 6.943 (0.728-66.261), P = 0.092]. CONCLUSIONS Blips are frequent (22.7%) among HIV-infected patients with sustained virological suppression on ART. HIV patients with blips and at least three consecutive detected, but not quantified, HIV-RNA determinations (<20 copies/mL) had a higher risk of VF. These findings highlight the relevance of maintaining HIV-RNA levels below the limits of quantification of current assays (<20 copies/mL).
A Flexemic Tagset for Polish

The article notes certain weaknesses of current efforts aiming at the standardization of POS tagsets for morphologically rich languages and argues that, in order to achieve clear mappings between tagsets, it is necessary to have clear and formal rules of delimiting POSs and grammatical categories within any given tagset. An attempt at constructing such a tagset for Polish is presented.
Slow Presynaptic and Fast Postsynaptic Components of Compound Long-Term Potentiation

Long-term potentiation (LTP) mediates learning and memory in the mammalian hippocampus. Whether a presynaptic or postsynaptic neuron principally enhances synaptic transmission during LTP remains controversial. Acute hippocampal slices were made from transgenic mouse strains that express synaptopHluorin in neurons. SynaptopHluorin is an indicator of synaptic vesicle recycling; thus, we monitored functional changes in presynaptic boutons of CA3 pyramidal cells by measuring changes in synaptopHluorin fluorescence. Simultaneously, we recorded field excitatory postsynaptic potentials to monitor changes in the strength of excitatory synapses between CA3 and CA1 pyramidal neurons. We found that LTP consists of two components, a slow presynaptic component and a fast postsynaptic component. The presynaptic mechanisms contribute mostly to the late phase of compound LTP, whereas the postsynaptic mechanisms are crucial during the early phase of LTP. We also found that protein kinase A (PKA) and L-type voltage-gated calcium channels are crucial for the expression of the presynaptic component of compound LTP, and NMDA channels are essential for that of the postsynaptic component of LTP. These data are the first direct evidence that presynaptic and postsynaptic components of LTP are temporally and mechanistically distinct.
Multilevel Approach of a 1-Year Program of Dietary and Exercise Interventions on Bone Mineral Content and Density in Metabolic Syndrome – the RESOLVE Randomized Controlled Trial

Background Weight loss is a public health concern in obesity-related diseases such as metabolic syndrome (MetS). However, restrictive diets might induce bone loss. The nature of exercise and whether exercise with weight loss programs can protect against potential bone mass deficits remains unclear. Moreover, compliance is essential in intervention programs. Thus, we aimed to investigate the effects that modality and exercise compliance have on bone mineral content (BMC) and density (BMD). Methods We investigated 90 individuals with MetS who were recruited for the 1-year RESOLVE trial. Community-dwelling seniors with MetS were randomly assigned into three different modalities of exercise (intensive resistance, intensive endurance, moderate mixed) combined with a restrictive diet. They were compared to 44 healthy controls who did not undergo the intervention. Results This intensive lifestyle intervention (15–20 hours of training/week + restrictive diet) resulted in weight loss, body composition changes and health improvements. Baseline BMC and BMD for total body, lumbar spine and femoral neck did not differ between MetS groups and between MetS and controls. Despite changes over time, BMC or BMD did not differ between the three modalities of exercise and when compared with the controls. However, independent of exercise modality, compliant participants increased their BMC and BMD compared with their less compliant peers. Decreases in total body lean mass and negative energy balance significantly and independently contributed to decreases in lumbar spine BMC. Conclusion After the one year intervention, differences relating to exercise modalities were not evident. However, compliance with an intensive exercise program resulted in a significantly higher bone mass during energy restriction than non-compliance. Exercise is therefore beneficial to bone in the context of a weight loss program. Trial Registration ClinicalTrials.gov NCT00917917
The sensitivity of linear regression coefficients' confidence limits to the omission of a confounder

Omitted variable bias can affect treatment effect estimates obtained from observational data due to the lack of random assignment to treatment groups. Sensitivity analyses adjust these estimates to quantify the impact of potential omitted variables. This paper presents methods of sensitivity analysis to adjust interval estimates of treatment effect---both the point estimate and standard error---obtained using multiple linear regression. Central to our approach is what we term benchmarking, the use of data to establish reference points for speculation about omitted confounders. The method adapts to treatment effects that may differ by subgroup, to scenarios involving omission of multiple variables, and to combinations of covariance adjustment with propensity score stratification. We illustrate it using data from an influential study of health outcomes of patients admitted to critical care.
PhishStorm: Detecting Phishing With Streaming Analytics

Despite the growth of prevention techniques, phishing remains an important threat since the principal countermeasures in use are still based on reactive URL blacklisting. This technique is inefficient due to the short lifetime of phishing Web sites, making recent approaches relying on real-time or proactive phishing URL detection techniques more appropriate. In this paper, we introduce PhishStorm, an automated phishing detection system that can analyze in real time any URL in order to identify potential phishing sites. PhishStorm can interface with any email server or HTTP proxy. We argue that phishing URLs usually have few relationships between the part of the URL that must be registered (low-level domain) and the remaining part of the URL (upper-level domain, path, query). We show in this paper that experimental evidence supports this observation and can be used to detect phishing sites. For this purpose, we define the new concept of intra-URL relatedness and evaluate it using features extracted from words that compose a URL based on query data from Google and Yahoo search engines. These features are then used in machine-learning-based classification to detect phishing URLs from a real dataset. Our technique is assessed on 96 018 phishing and legitimate URLs that result in a correct classification rate of 94.91% with only 1.44% false positives. An extension for a URL phishingness rating system exhibiting high confidence rate ( $>$ 99%) is proposed. We discuss in this paper efficient implementation patterns that allow real-time analytics using Big Data architectures such as STORM and advanced data structures based on the Bloom filter.
Phycobilisome truncation causes widespread proteome changes in Synechocystis sp. PCC 6803

In cyanobacteria such as Synechocystis sp. PCC 6803, large antenna complexes called phycobilisomes (PBS) harvest light and transfer the energy to the photosynthetic reaction centers. Modification of the light harvesting machinery in cyanobacteria has widespread consequences, causing changes in cell morphology and physiology. In the current study, we investigated the effects of PBS truncation on the proteomes of three Synechocystis 6803 PBS antenna mutants. These range from the progressive truncation of phycocyanin rods in the CB and CK strains, to full removal of PBS in the PAL mutant. Comparative quantitative protein results revealed surprising changes in protein abundances in the mutant strains. Our results showed that PBS truncation in Synechocystis 6803 broadly impacted core cellular mechanisms beyond light harvesting and photosynthesis. Specifically, we observed dramatic alterations in membrane transport mechanisms, where the most severe PBS truncation in the PAL strain appeared to suppress the cellular utilization and regulation of bicarbonate and iron. These changes point to the role of PBS as a component critical to cell function, and demonstrate the continuing need to assess systems-wide protein based abundances to understand potential indirect phenotypic effects.
Stock Market Returns and CorporateGovernance in Capital MarketEquilibrium

This paper addresses two questions. First, why competition for funds among firms does not eliminate control benefits by inducing them to adopt more shareholder friendly governance provisions? Second, what determines the heterogeneity of the governance provisions among companies in the same jurisdiction? To address these questions we construct a simple model that incorporates the determination of a key corporate governance provision, the amount of control benefits, in the CAPM framework. Our model offers two main testable implications. First, stocks with a lower β have higher control benefits. Second, an increase in firm-specific cash flow volatility is associated with a decrease in control benefits extraction. CAPM regression. We test these propositions on a sample of U.S. companies and find that higher control benefits as measured by the index of Gompers, Ishii, and Metrick (2003) of antitakeover provisions (GIM Index) are higher in companies with lower β and with lower idiosyncratic volatility. ∗Preliminary and incomplete draft. We thank Paul Laux and various seminar audiences for useful discussions and Ludovic Calès for excellent research assistance. The usual disclaimer applies. Corresponding author: Bruno M. Parigi, brunomaria.parigi@unipd.it
Are We Nearing an Era of Chemotherapy-Free Management of Indolent Lymphoma?

Indolent B-cell lymphomas are heterogeneous, comprising three grades of follicular lymphoma, small lymphocytic lymphoma, Waldenstöm macroglobulinemia, marginal zone lymphoma, and most recently, possibly low proliferative mantle cell lymphoma. These lymphomas are characterized by a high responsiveness to chemotherapy or immunochemotherapy; however, in most cases, conventional therapy might not offer a cure. Furthermore, the patient's age at diagnosis, at time to first or subsequent relapses, as well as potential comorbidities often preclude the use of chemotherapy. Recent progress has been made in our understanding of dysregulated pathways and immunologic antitumor responses in indolent lymphoma. Major therapeutic advances have been achieved in the development of nonchemotherapeutic agents, making “chemo-free” treatment a near-future reality. In this article, we highlight these promising approaches, such as the combination of anti-CD20 antibodies with immunomodulatory drugs, with mAbs directed against other surface antigens such as CD22, with immunomodulatory antibodies such as PD-1, or with inhibitors of key steps in the B-cell receptor pathway signaling. However, the cost of such therapies and potential, albeit manageable, toxicity should be considered. Phase III trials will confirm the benefit of these new treatment strategies that do not require a chemotherapeutic drug and help us identify their exact place in the therapeutic armamentarium for indolent lymphoma. Here we focus on follicular lymphoma, which is the most frequent subtype of indolent lymphoma and for which an increasing body of evidence has emerged that supports the dawn of a new era of chemotherapy-free treatment. See all articles in this CCR Focus section, “Paradigm Shifts in Lymphoma. ” Clin Cancer Res; 20(20); 5226–39. ©2014 AACR.
The charge transport characteristics of polyimide under electron beam and dc voltage

Deposited charges in dielectric material under electron-beam radiation have an important influence on dc vacuum surface flashover. This paper investigates the charge transport characteristics of polyimide under electron-beam radiation and dc voltage. Based on the actual size of electrodes and polyimide, a physical model of electron-beam radiation is proposed. Considered the processes of charge deposition and transport and accumulation in polyimide radiated by low-energy electrons (electron energy: 5-30 keV, electron-beam density: 10-10 ~10-7A/m2), the distributions of space charge, potential and electric field can be obtained, and the total electric field at cathode triple junction under the combined action of electron radiation and dc voltage are analyzed. The calculation results indicate that when the electron-beam density is less relatively (<;10-9 A/m2), the weakening effect of built-in electric field on applied electric field is unobvious. With the increase of electronbeam density, the built-in electric field is gradually increased, resulting in the decrease of total electric field at the cathode triple junction. The total electric field is 8×105 V/m under the electron-beam density of 10-7 A/m2. It will reduce the initial electron emission at the cathode triple junction, and may enhance surface flashover voltage of dielectric material. Further experiment study will be carried out.
Manipulation of Playing Field's Length/Width Ratio and Neutral Players' Positioning: Activity Profile and Motor Behavior Demands during Positional Possession Soccer Small Sided Games in Young Elite Soccer Players

This study aimed to examine how changes in pitch length/width ratio and neutral players' positioning could modify the activity profile and motor behaviour demands during small-sided positional possession soccer games. 22 young male elite players divided in 2 teams (A and B) of 11 players participated in the study. All players participated in a positional possession game (4-a-side + 3 neutral players) on two different pitch formats with opposite length/width ratios (WIDE: 25 x 35 m; LONG: 35 x 25 m) and two different kinds of positioning for neutral players (VERTICAL: positioned high; HORIZONTAL: wide). The time motion variables of each player were recorded using a 15 Hz portable GPS. Average player displacement in width was significantly higher in WIDE format, while average player displacement in depth was significantly greater in LONG format (p < .001). Moreover, an increased activity profile was observed in regular team players with respect to neutral players (p < .001). These results highlight the physical and motor behaviour demands in small sided positional possession games. Furthermore, the different physical tasks required by various pitch formats and player positions were underlined. This information can help coaches to set up game-based training sessions.
The Geography of Transport Systems

1. Transportation and Geography 2. Transportation Systems and Networks 3. Economic and Spatial Structure of Transport Systems 4. Transportation Modes 5. Transportation Terminals 6. International and Regional Transportation 7. Urban Transportation 8. Transport and Environment 9. Transport Planning and Policy Conclusion: Issues and Challenges in Transport Geography. Glossary and Index