Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of conventional and internally cured concrete bridge decks in Utah : Mountain View corridor project.

The objectives of this research were to (1) monitor in-situ moisture and diffusivity for both conventional concrete and concrete containing pre-wetted lightweight fine aggregate (LWFA), (2) compare deck performance in terms of early-age cracking, compressive strength, and chloride ingress, and (3) compare concrete properties in terms of compressive strength, chloride permeability, elastic modulus, and water content in the laboratory using cylinders cast in the field at the time of deck construction. The research involved field and laboratory evaluations of four newly constructed bridge decks located in northern Utah, two constructed using conventional concrete and two constructed using pre-wetted LWFA to promote internal curing. Data from sensors embedded in the concrete decks indicate that the volumetric moisture content and electrical conductivity of the internally cured concrete were higher than those of the conventional concrete during the 2-year monitoring period. Laboratory data indicate that the internally cured concrete was weaker at 1 year following deck construction, passed less current in rapid chloride permeability testing, had a lower modulus in free-free resonant testing, and had a higher gravimetric moisture content than the conventional concrete. In the field, the internally cured concrete was weaker at 2 years in Schmidt rebound hammer testing and exhibited greater chloride concentrations at both 1 and 2 years than the conventional concrete. The conventional concrete bridge decks had more reflection cracking from the joints between the underlying pre-cast half-deck panels than the internally cured concrete decks.
POPULATION DYNAMICS OF COLLEMBOLA AND ACARI IN WETLANDS AND CROPLANDS IN INDO-GANGETIC PLAINS OF NORTH BIHAR

Twelve genera of Collembola belonging to four different families were recorded from cropland field, whereas only eight genera of three different families of Collembola could be recorded from the wetland field. Similarly sixteen different species of mites and a Nova species were found in cropland field whereas only eight species of mites were present in wetland field implying thereby that inundation is not favored by certain species of Collembolans and mites. The impact of water logging on population densities of both the groups of fauna was clearly evidenced. Out of the two peaks exhibited by Collembolan one was more pronounced in the month of September while the other was less pronounced in the month of March in cropland. In wetland higher numbers was observed in the month of March but Water logging rendered zero population of both the groups of soil fauna in the month of August and September. Mites had also a peak in the month of August and March in cropland and wetland fields respectively. KEY WORDS Mites, Acari Collembola Wetland Cropland Inundation
Do sedentary older adults benefit from community-based exercise? Results from the Active Start program.

PURPOSE This study assessed the effectiveness of Active Start, a community-based behavior change and fitness program, designed to promote physical activity among sedentary community-dwelling older adults. DESIGN AND METHODS A quasi-experimental design was used. Data were analyzed using a within-group pretest-post-test design to calculate changes in the intervention group and changes in the waitlist comparison group. Further analyses were conducted after the comparison group completed the intervention. Paired t tests were employed to analyze unadjusted mean changes in physical performance measures from pretest to post-test. Repeated measures analysis of covariance (using SAS Proc Mixed) was then conducted to calculate the adjusted mean change for the intervention group. RESULTS Significant improvement was found on all performance measures (strength, flexibility, and balance) for the intervention group as a whole. Similar improvements were found among subgroups (Whites, African Americans, and Hispanics). No significant changes were found in the comparison group when they were in the control condition; however, they significantly improved on all measures after completing the intervention. IMPLICATIONS This study suggests that a community-based physical activity program benefits sedentary, racially, and ethnically diverse older adults by coupling a behavioral change support group and fitness classes.
Current approaches to avoid the culling of day‐old male chicks in the layer industry, with special reference to spectroscopic methods

Abstract The negative correlation between fattening and laying performance prevents breeding improvement in both laying performance and meat yield. Therefore, specialized chicken lines have been bred in order to achieve either an efficient production of high‐quality eggs or high growth rates. As a result, day‐old male chicks are culled in the layer hatchery, which poses animal welfare and ethical problems. Breeding companies, scientific groups, and hatcheries are attempting to resolve this issue, with a common aim to find feasible alternatives for the routine killing of male layer chicks. Some approaches aim to influence the sex ratio, while others target at the economically feasible use of the male layer offspring, such as the fattening of “laying hen brothers” or crossbreedings of layers and broilers to create “dual‐purpose chickens. ” Another approach is the sex determination prior to hatch. One of the prerequisites of in ovo sex determination is a practicable method that can be used in industry. The analysis needs to be rapid, cost‐efficient, and highly precise; in addition, negative impacts on hatching rate, animal health, and/or performance parameters should be limited. Furthermore, sex determination should be performed before the sensory nervous system's response of the chick embryo to certain or potentially harmful stimuli is developed, which according to current knowledge is before the d 7 of incubation.
Relation of body mass index to risk of developing inflammatory bowel disease amongst women in the Danish National Birth Cohort

Background Crohn’s disease (CD) has traditionally been associated with weight loss and low BMI, yet paradoxically obesity has recently been suggested as a risk factor for CD, but not for ulcerative colitis (UC). We therefore hypothesized that the relation between BMI and CD is U shaped. Aim To conduct a large population-based prospective cohort study of BMI and later risk of IBD, taking age at IBD diagnosis into account. Methods A cohort of 74,512 women from the Danish National Birth Cohort, with BMI measured pre-pregnancy and 18 months after delivery, was followed for 1,022,250 person-years for development of IBD, according to the Danish National Patient Register. Associations were tested by Cox regression. Results Overweight subjects (25≤BMI<30 kg/m2) had the lowest risk of CD, whereas obesity (BMI≥30kg/m2) increased the risk of CD at all ages, and low BMI (BMI<18.5kg/m2) associated with CD diagnosed at age 18-<40 years. Hence, using normal weight subjects as the reference, adjusted HRs for risk of developing CD (at age 18-<40 years) were 1.8(95%CI, 0.9–3.7) for underweight, 0.6(0.3–1.2) for overweight, and 1.5(0.8–2.7) for obese individuals (pre-pregnancy BMI). HRs were greater for BMI determined 18 months after delivery. Splines for CD risk according to waist:height ratio confirmed a U-shaped relationship with CD occurring <40 years, and a linear relationship with CD diagnosed at age 40+. There was no relationship between BMI and risk of UC. Conclusion For the first time, we demonstrate that both high BMI and low BMI are risk factors for CD. Underweight may be a pre-clinical manifestation of disease being present many years before onset with obesity being a true risk factor. This raises the question as to whether there may be two distinct forms of CD.
DETAILED CHARACTERIZATION OF CHOROIDAL MORPHOLOGIC AND VASCULAR FEATURES IN AGE-RELATED MACULAR DEGENERATION AND POLYPOIDAL CHOROIDAL VASCULOPATHY

Purpose: To characterize and compare morphologic and vascular features of the choroid in patients with typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) and to determine if PCV subtypes can be identified based on these choroidal features. Methods: Choroidal features of patients with AMD and PCV recruited from the prospectively planned Asian AMD Phenotyping Study were analyzed. Patients underwent choroidal imaging using spectral-domain optical coherence tomography with enhanced depth imaging. Raw optical coherence tomographic images were loaded on a custom-written application on MATLAB that enabled delineation for detailed morphologic and vascular analyses, including the curvature of the choroid–sclera interface, number of inflection points, choroidal thickness and choroidal vascular area within the macular (6 mm centered on fovea) and foveal (1.5 mm centered on fovea) regions. An inflection point represents the contour of the choroid–sclera interface, with >1 point signaling irregular shape. Results: A total of 156 eyes of 156 patients (78 affected eyes of 78 patients with typical AMD and 78 affected eyes of 78 patients with PCV) were analyzed. Eyes with PCV had thicker baseline choroidal thickness and greater choroidal vascular area compared with those with typical AMD (P < 0.05); these differences were no longer significant after adjusting for age and hypertension (P > 0.05). Typical PCV subtype with choroidal thickness of ≥257 &mgr;m had significantly greater choroidal vascular area at macular (mean difference = 0.054 mm2; P < 0.001) and foveal (mean difference = 0.199 mm2; P < 0.001) regions compared with eyes with typical AMD. However, eyes with PCV without thick choroid had similar choroidal vascular area as eyes with typical AMD. Conclusion: Based on the choroidal vascular features, two subtypes of PCV can be classified: typical PCV with increased choroid vascularity and polypoidal choroidal neovascularization with low choroidal vascularity. These data provide further understanding of different AMD and PCV subtypes.
Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules

Maytansine is a potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations. However, its side effects and lack of tumor specificity have prevented successful clinical use. Recently, antibody-conjugated maytansine derivatives have been developed to overcome these drawbacks. Several conjugates show promising early clinical results. We evaluated the effects on microtubule polymerization and dynamic instability of maytansine and two cellular metabolites (S-methyl-DM1 and S-methyl-DM4) of antibody-maytansinoid conjugates that are potent in cells at picomolar levels and that are active in tumor-bearing mice. Although S-methyl-DM1 and S-methyl-DM4 inhibited polymerization more weakly than maytansine, at 100 nmol/L they suppressed dynamic instability more strongly than maytansine (by 84% and 73%, respectively, compared with 45% for maytansine). However, unlike maytansine, S-methyl-DM1 and S-methyl-DM4 induced tubulin aggregates detectable by electron microscopy at concentrations ≥2 μmol/L, with S-methyl-DM4 showing more extensive aggregate formation than S-methyl-DM1. Both maytansine and S-methyl-DM1 bound to tubulin with similar KD values (0.86 ± 0.2 and 0.93 ± 0.2 μmol/L, respectively). Tritiated S-methyl-DM1 bound to 37 high-affinity sites per microtubule (KD, 0.1 ± 0.05 μmol/L). Thus, S-methyl-DM1 binds to high-affinity sites on microtubules 20-fold more strongly than vinblastine. The high-affinity binding is likely at microtubule ends and is responsible for suppression of microtubule dynamic instability. Also, at higher concentrations, S-methyl-DM1 showed low-affinity binding either to a larger number of sites on microtubules or to sedimentable tubulin aggregates. Overall, the maytansine derivatives that result from cellular metabolism of the antibody conjugates are themselves potent microtubule poisons, interacting with microtubules as effectively as or more effectively than the parent molecule. Mol Cancer Ther; 9(10); 2689–99. ©2010 AACR.
Evaluation of Analysis by Cross-Validation. Part II: Diagnostic and Optimization of Analysis Error Covariance

We present a general theory of estimation of analysis error covariances based on cross-validation as well as a geometric interpretation of the method. In particular, we use the variance of passive observation-minus-analysis residuals and show that the true analysis error variance can be estimated, without relying on the optimality assumption. This approach is used to obtain near optimal analyses that are then used to evaluate the air quality analysis error using several different methods at active and passive observation sites. We compare the estimates according to the method of Hollingsworth-Lonnberg, Desroziers et al., a new diagnostic we developed, and the perceived analysis error computed from the analysis scheme, to conclude that, as long as the analysis is near optimal, all estimates agree within a certain error margin.
Factors related to the comorbidity between oppositional defiant disorder and anxiety disorders in preschool children

ABSTRACT Background and objectives: The aim of the study is to identify factors related to comorbid oppositional defiant disorder (ODD) and anxiety disorders (ADs). Design: A sample of 622 children was assessed longitudinally at 3 and 5 years of age. Methods: At baseline, there were 310 boys (49.8%), most participants were of Caucasian–white ethnicity (89.1%) and attended to public school (64.0%), and families’ socioeconomic status was 64.3% medium-high, 14.1% medium and 20.5% medium-low. Children diagnosed with ODD and/or AD were selected: n = 103 at 3 years of age (44 ODD, 42 AD and 17 ODD + AD) and n = 106 at 5 years of age (31 ODD, 60 AD and 15 ODD + AD). Results: High levels of the child’s negative affectivity and the mother’s aggressive behavior (versus AD), and high scores in the father’s psychopathology measurements (versus ODD) were related to the presence of comorbid ODD + AD at 3 years of age. High scores in approach-positive anticipation, fears (only in boys, in girls the reverse effect occurred) compared to ODD and AD independently and aggressive behavior (versus AD), and low scores for smiling and laughter (versus ODD only and AD only) were predictive of comorbidity at the 5 years of age. Conclusions: Temperament traits may be a common factor in explaining longitudinal ODD + AD comorbidity.
Peer-Based Social Media Features in Behavior Change Interventions: Systematic Review

Background Incorporating social media features into digital behavior change interventions (DBCIs) has the potential to contribute positively to their success. However, the lack of clear design principles to describe and guide the use of these features in behavioral interventions limits cross-study comparisons of their uses and effects. Objective The aim of this study was to provide a systematic review of DBCIs targeting modifiable behavioral risk factors that have included social media features as part of their intervention infrastructure. A taxonomy of social media features is presented to inform the development, description, and evaluation of behavioral interventions. Methods Search terms were used in 8 databases to identify DBCIs that incorporated social media features and targeted tobacco smoking, diet and nutrition, physical activities, or alcohol consumption. The screening and review process was performed by 2 independent researchers. Results A total of 5264 articles were screened, and 143 articles describing a total of 134 studies were retained for full review. The majority of studies (70%) reported positive outcomes, followed by 28% finding no effects with regard to their respective objectives and hypothesis, and 2% of the studies found that their interventions had negative outcomes. Few studies reported on the association between the inclusion of social media features and intervention effect. A taxonomy of social media features used in behavioral interventions has been presented with 36 social media features organized under 7 high-level categories. The taxonomy has been used to guide the analysis of this review. Conclusions Although social media features are commonly included in DBCIs, there is an acute lack of information with respect to their effect on outcomes and a lack of clear guidance to inform the selection process based on the features’ suitability for the different behaviors. The proposed taxonomy along with the set of recommendations included in this review will support future research aimed at isolating and reporting the effects of social media features on DBCIs, cross-study comparisons, and evaluations.
Armanni–Ebstein Lesions in Terminal Hyperglycemia

Armanni–Ebstein lesions (AEL) occur in deaths related to uncontrolled diabetes mellitus. To investigate the relationship between AEL and terminal hyperglycemia, we retrospectively reviewed 71 cases with vitreous glucose levels ≥11.1 mmol/L; 27 (38%) cases had AEL (vitreous glucose 14.0–77.3 mmol/L); and 44 cases (62%) did not (vitreous glucose 11.1–91.9 mmol/L). There was no significant difference (p = 0.271) in vitreous glucose levels between the cases with AEL (mean 39.2, SD 16.7 mmol/L) and those without (mean 34.2, SD 19.8 mmol/L). Similarly, there was no difference in the degree of dehydration, renal failure, or osmolality. However, there was a significantly higher level of β‐hydroxybutyrate among the cases with AEL compared to those without (p = 0.007), suggesting that ketoacidosis may facilitate the development of AEL. Given the possible synergistic role of β‐hydroxybutyrate, the correlation between AEL and terminal hyperglycemia in animal studies may not be applicable to humans. AEL may also possibly occur with sublethal elevations in glucose.
Non-Orthogonal Multiple Access for mmWave Drone Networks With Limited Feedback

Unmanned aerial vehicle (UAV) base stations (BSs) can be a promising solution to provide connectivity and quality-of-service guarantees during temporary events and after disasters. In this paper, we consider a scenario where UAV-BSs are serving a large number of mobile users in a hot spot area (e.g., in a stadium). We introduce non-orthogonal multiple-access (NOMA) transmission at UAV-BSs to serve more users simultaneously considering user distances as the available feedback for a user ordering during NOMA formulation. With millimeter-wave transmission and multi-antenna techniques, we assume that UAV-BS generates directional beams and multiple users are served simultaneously within the same beam. However, due to the limitations of physical vertical beamwidth of the UAV-BS beam, it may not be possible to cover the entire user region at UAV altitudes of practical relevance. During such situations, a beam scanning approach is proposed to maximize the achievable sum rates. We develop a comprehensive framework over which outage probabilities and respective sum rates are derived rigorously and we investigate the optimal operational altitude of UAV-BS to maximize the sum rates using our analytical framework. Our analysis shows that NOMA with distance feedback can provide better outage sum rates than orthogonal multiple access.
Relationship between nurse psychological empowerment and job satisfaction: A systematic review and meta‐analysis

AIMS This systematic review and meta-analysis aimed to synthesize and analyse studies that explored the relationship between the psychological empowerment and job satisfaction of nurses. BACKGROUND Nurse turnover is an important cause of staff shortage. Job satisfaction is a major predictor of nurse turnover and is connected to the psychological empowerment of nurses. DESIGN This systematic review and meta-analysis is based on the Joanna Briggs Institute guidelines. DATA SOURCES A total of 1,572 articles on psychological empowerment and job satisfaction were retrieved from PubMed, PsycINFO, EMBASE and Web of Science. The articles were written in English and published before or by April 2017. METHODS Studies on the relationship between psychological empowerment and job satisfaction were summarized. RESULTS The majority of the included studies revealed that psychological empowerment and job satisfaction are significantly correlated. Only two studies showed that the two factors are not significantly correlated. The result of this meta-analysis is consistent with the results of most studies. One study reported that psychological empowerment partially mediates the structural empowerment and job satisfaction of school health nurses. Two studies, however, did not find that the mediating role of psychological empowerment between structural empowerment and job satisfaction. CONCLUSION The results of this review provided evidence for the importance of psychological empowerment for the job satisfaction of among nurses. Exploring the correlation between psychological empowerment and job satisfaction can provide guidelines and recommendation for the development of strategies to promote nurse retention and alleviate nursing shortage.
Learning One-hidden-layer Neural Networks with Landscape Design

We consider the problem of learning a one-hidden-layer neural network: we assume the input $x\in \mathbb{R}^d$ is from Gaussian distribution and the label $y = a^\top \sigma(Bx) + \xi$, where $a$ is a nonnegative vector in $\mathbb{R}^m$ with $m\le d$, $B\in \mathbb{R}^{m\times d}$ is a full-rank weight matrix, and $\xi$ is a noise vector. We first give an analytic formula for the population risk of the standard squared loss and demonstrate that it implicitly attempts to decompose a sequence of low-rank tensors simultaneously. Inspired by the formula, we design a non-convex objective function $G(\cdot)$ whose landscape is guaranteed to have the following properties: 1. All local minima of $G$ are also global minima. 2. All global minima of $G$ correspond to the ground truth parameters. 3. The value and gradient of $G$ can be estimated using samples. With these properties, stochastic gradient descent on $G$ provably converges to the global minimum and learn the ground-truth parameters. We also prove finite sample complexity result and validate the results by simulations.
Edge Effects in Angle-Ply Composite Laminates*

This paper presents the results of a zeroth-order solution for edge effects in angle-ply composite laminates obtained using perturbation tech niques and a limiting free body approach. The general solution for [±θ] laminates is applied to the special case of a [±45]s graphite/epoxy lamin ate. Interlaminar stress distributions are obtained as a function of the laminate thickness-to-width ratio h/b and compared to finite difference results. The solution predicts stable, continuous stress distributions, determines finite maximum tensile interlaminar normal stress σz, and provides mathe matical evidence for singular interlaminar shear stresses τ xz and τyz in [±45] graphite/epoxy laminates.
Development of rapid bioconversion with integrated recycle technology for ethanol production from extractive ammonia pretreated corn stover

High enzyme loading and low productivity are two major issues impeding low cost ethanol production from lignocellulosic biomass. This work applied rapid bioconversion with integrated recycle technology (RaBIT) and extractive ammonia (EA) pretreatment for conversion of corn stover (CS) to ethanol at high solids loading. Enzymes were recycled via recycling unhydrolyzed solids. Enzymatic hydrolysis with recycled enzymes and fermentation with recycled yeast cells were studied. Both enzymatic hydrolysis time and fermentation time were shortened to 24 h. Ethanol productivity was enhanced by two times and enzyme loading was reduced by 30%. Glucan and xylan conversions reached as high as 98% with an enzyme loading of as low as 8.4 mg protein per g glucan. The overall ethanol yield was 227 g ethanol/kg EA‐CS (191 g ethanol/kg untreated CS). Biotechnol. Bioeng. 2017;114: 1713–1720. © 2017 Wiley Periodicals, Inc.