Miracle-dz/UniFAR-FTUs huggingface dataset:
CRIUS: User-Friendly Database Design

Non-technical users are increasingly adding structures to their data. This gives rise to the need for database design. However, traditional database design is deliberate and heavy-weight, requiring technical expertise that everyday users may not possess. For this reason, we propose that users of personal data management applications should be able to create and refine data structures in an ad-hoc way over time, thereby "organically" growing their schemas. For this purpose, we develop a spreadsheet-like direct manipulation interface. We show how integrity constraints can still provide value, even in this scenario of frequent schema and data modifications. We also develop a back-end database implementation to support this interface, with a design that permits schema changes at a low cost. We have folded these ideas into a system, called CRIUS, which supports a nested data model and a graphical user interface. From the user's perspective, the chief advantages of CRIUS are its support for simple schema definition and modification through an intuitive drag-and-drop interface, as well as its guidance towards user data entry based on incrementally updated data integrity. We have evaluated CRIUS by means of user studies and performance studies. The user studies indicate that 1) CRIUS makes it much easier for users to design a database, as compared to state-of-the-art GUI database design tools, and 2) CRIUS makes user data entry more efficient and less error-prone. The performance experiments show that 1) the incremental integrity update in CRIUS is very efficient, making the data entry guidance applicable and 2) the backend database implementation in CRIUS significantly improves the performance of schema update tasks, without a significant impact on other operations.
Ultrastructural alterations in field carcinogenesis measured by enhanced backscattering spectroscopy

Abstract. Optical characterization of biological tissue in field carcinogenesis offers a method with which to study the mechanisms behind early cancer development and the potential to perform clinical diagnosis. Previously, low-coherence enhanced backscattering spectroscopy (LEBS) has demonstrated the ability to discriminate between normal and diseased organs based on measurements of histologically normal-appearing tissue in the field of colorectal (CRC) and pancreatic (PC) cancers. Here, we implement the more comprehensive enhanced backscattering (EBS) spectroscopy to better understand the structural and optical changes which lead to the previous findings. EBS provides high-resolution measurement of the spatial reflectance profile P(rs) between 30 microns and 2.7 mm, where information about nanoscale mass density fluctuations in the mucosa can be quantified. A demonstration of the length-scales at which P(rs) is optimally altered in CRC and PC field carcinogenesis is given and subsequently these changes are related to the tissue’s structural composition. Three main conclusions are made. First, the most significant changes in P(rs) occur at short length-scales corresponding to the superficial mucosal layer. Second, these changes are predominantly attributable to a reduction in the presence of subdiffractional structures. Third, similar trends are seen for both cancer types, suggesting a common progression of structural alterations in each.
Chemoprevention of Basal Cell Carcinomas in the ptc1+/– Mouse – Green and Black Tea

Skin cancers are a rising menace as their incidence increases, attributed in part to increasing ultraviolet radiation exposure. This increasing problem has stimulated efforts to devise useful preventive approaches. The uncertain efficacy of exhortations to avoid sun exposure and to use protective clothing and sunscreens to reduce damage when exposed argue for the development of an oral chemopreventive agent. Bickers and others have studied the effects and mechanisms of tea and of its putative active components on inhibition of skin cancer in experimental models. To continue this work, we have studied the effects of oral green tea and black tea on a new model of ultraviolet-induced skin carcinogenesis – the development of basal cell carcinomas in ptc1+/– mice. To our surprise, we have found that tea preparations which others have used to prevent squamous cell carcinoma formation in mice fail to inhibit basal cell carcinogenesis in our model, suggesting that prevention of this cancer may require special, tumor-specific approaches.
Extent and relevance of stacking disorder in “ice Ic”

A solid water phase commonly known as “cubic ice” or “ice Ic” is frequently encountered in various transitions between the solid, liquid, and gaseous phases of the water substance. It may form, e.g., by water freezing or vapor deposition in the Earth’s atmosphere or in extraterrestrial environments, and plays a central role in various cryopreservation techniques; its formation is observed over a wide temperature range from about 120 K up to the melting point of ice. There was multiple and compelling evidence in the past that this phase is not truly cubic but composed of disordered cubic and hexagonal stacking sequences. The complexity of the stacking disorder, however, appears to have been largely overlooked in most of the literature. By analyzing neutron diffraction data with our stacking-disorder model, we show that correlations between next-nearest layers are clearly developed, leading to marked deviations from a simple random stacking in almost all investigated cases. We follow the evolution of the stacking disorder as a function of time and temperature at conditions relevant to atmospheric processes; a continuous transformation toward normal hexagonal ice is observed. We establish a quantitative link between the crystallite size established by diffraction and electron microscopic images of the material; the crystallite size evolves from several nanometers into the micrometer range with progressive annealing. The crystallites are isometric with markedly rough surfaces parallel to the stacking direction, which has implications for atmospheric sciences.
Documenting the Density of Subtidal Marine Debris across Multiple Marine and Coastal Habitats

Marine debris is recognised globally as a key threatening process to marine life, but efforts to address the issue are hampered by the lack of data for many marine habitats. By developing standardised protocols and providing training in their application, we worked with >300 volunteer divers from 11 underwater research groups to document the scale of the subtidal marine debris problem at 120 sites across >1000 km of the coast of NSW, Australia. Sampling consisted of replicated 25×5 m transects in which all debris was identified, counted, and, where appropriate, removed. Sites ranged from estuarine settings adjacent to major population centres, to offshore islands within marine parks. Estuaries and embayments were consistently found to be the most contaminated habitats. Fishing-related items (and especially monofilament and braided fishing line) were most prevalent at the majority of sites, although food and drink items were important contributors at sites adjacent to population centres. The results identified damaging interactions between marine debris and marine biota at some key locations, highlighting the need for management intervention to ensure habitat sustainability. This study reinforces the important contribution that volunteers can make to assessing conservation issues requiring broad-scale data collection. In this case, citizen scientists delivered data that will inform, and help to prioritise, management approaches at both statewide and local scales. These initial data also provide an important baseline for longer-term, volunteer-based monitoring programs.
Comparing deep neural networks against humans: object recognition when the signal gets weaker

Human visual object recognition is typically rapid and seemingly effortless, as well as largely independent of viewpoint and object orientation. Until very recently, animate visual systems were the only ones capable of this remarkable computational feat. This has changed with the rise of a class of computer vision algorithms called deep neural networks (DNNs) that achieve human-level classification performance on object recognition tasks. Furthermore, a growing number of studies report similarities in the way DNNs and the human visual system process objects, suggesting that current DNNs may be good models of human visual object recognition. Yet there clearly exist important architectural and processing differences between state-of-the-art DNNs and the primate visual system. The potential behavioural consequences of these differences are not well understood. We aim to address this issue by comparing human and DNN generalisation abilities towards image degradations. We find the human visual system to be more robust to image manipulations like contrast reduction, additive noise or novel eidolon-distortions. In addition, we find progressively diverging classification error-patterns between humans and DNNs when the signal gets weaker, indicating that there may still be marked differences in the way humans and current DNNs perform visual object recognition. We envision that our findings as well as our carefully measured and freely available behavioural datasets provide a new useful benchmark for the computer vision community to improve the robustness of DNNs and a motivation for neuroscientists to search for mechanisms in the brain that could facilitate this robustness.
Thermal photon dispersion law and modified black‐body spectra

Based on the postulate that photon propagation is governed by an SU(2) gauge principle we numerically compute the one‐loop dispersion for thermalized photon propagation on the radiatively induced mass shell. Formerly, the dispersion was addressed by assuming p2 = 0. While this approximation turns out to be excellent for temperatures ≤ 2 TCMB the exact result exhibits a much faster (power‐like) shrinking of the gap in the black‐body spectral intensity with rising temperature. Our previous statements on anomalous large‐angle CMB temperature‐temperature correlations, obtained in the approximation p2 = 0, remain valid.
General fixed points of quasi-local frustration-free quantum semigroups: from invariance to stabilization

We investigate under which conditions a mixed state on a finite-dimensional multipartite quantum system may be the unique, globally stable fixed point of frustration-free semigroup dynamics subject to specified quasi-locality constraints. Our central result is a linear-algebraic necessary and sufficient condition for a generic (full-rank) target state to be frustration-free quasi-locally stabilizable, along with an explicit procedure for constructing Markovian dynamics that achieve stabilization. If the target state is not full-rank, we establish sufficiency under an additional condition, which is naturally motivated by consistency with pure-state stabilization results yet provably not necessary in general. Several applications are discussed, of relevance to both dissipative quantum engineering and information processing, and non-equilibrium quantum statistical mechanics. In particular, we show that a large class of graph product states (including arbitrary thermal graph states) as well as Gibbs states of commuting Hamiltonians are frustration-free stabilizable relative to natural quasi-locality constraints. Likewise, we provide explicit examples of non-commuting Gibbs states and non-trivially entangled mixed states that are stabilizable despite the lack of an underlying commuting structure, albeit scalability to arbitrary system size remains in this case an open question.
Spatial and temporal population genetic variation and structure of Nothotsuga longibracteata (Pinaceae), a relic conifer species endemic to subtropical China

Nothotsuga longibracteata, a relic and endangered conifer species endemic to subtropical China, was studied for examining the spatial-temporal population genetic variation and structure to understand the historical biogeographical processes underlying the present geographical distribution. Ten populations were sampled over the entire natural range of the species for spatial analysis, while three key populations with large population sizes and varied age structure were selected for temporal analyses using both nuclear microsatellites (nSSR) and chloroplast microsatellites (cpSSR). A recent bottleneck was detected in the natural populations of N. longibracteata. The spatial genetic analysis showed significant population genetic differentiation across its total geographical range. Notwithstanding, the temporal genetic analysis revealed that the level of genetic diversity between different age class subpopulations remained constant over time. Eleven refugia of the Last Glacial Maximum were identified, which deserve particular attention for conservation management.
Reorganization of microtubules in endosperm cells and cell fragments of the higher plant Haemanthus in vivo

The reorganization of the microtubular meshwork was studied in intact Haemanthus endosperm cells and cell fragments (cytoplasts). This higher plant tissue is devoid of a known microtubule organizating organelle. Observations on living cells were correlated with microtubule arrangements visualized with the immunogold method. In small fragments, reorganization did not proceed. In medium and large sized fragments, microtubular converging centers formed first. Then these converging centers reorganized into either closed bushy microtubular spiral or chromosome-free cytoplasmic spindles/phragmoplasts. Therefore, the final shape of organized microtubular structures, including spindle shaped, was determined by the initial size of the cell fragments and could be achieved without chromosomes or centrioles. Converging centers elongate due to the formation of additional structures resembling microtubular fir trees. These structures were observed at the pole of the microtubular converging center in anucleate fragments, accessory phragmoplasts in nucleated cells, and in the polar region of the mitotic spindle during anaphase. Therefore, during anaphase pronounced assembly of new microtubules occurs at the polar region of acentriolar spindles. Moreover, statistical analysis demonstrated that during the first two-thirds of anaphase, when chromosomes move with an approximately constant speed, kinetochore fibers shorten, while the length of the kinetochore fiber complex remains constant due to the simultaneous elongation of their integral parts (microtubular fir trees). The half-spindle shortens only during the last one-third of anaphase. These data contradict the presently prevailing view that chromosome-to-pole movements in acentriolar spindles of higher plants are concurrent with the shortening of the half-spindle, the self- reorganizing property of higher plant microtubules (tubulin) in vivo. It may be specific for cells without centrosomes and may be superimposed also on other microtubule-related processes.
Natural-graphite-sheet based heat sinks

Novel staggered plate fin heat sinks made of natural graphite sheets are presented and their performance is demonstrated via a direct comparison with aluminum. Measurements in a simple wind tunnel with a diode acting as a heat source show that the junction-to-ambient thermal resistance of the graphite heat sink is 31% lower when no electrically insulating thermal interface material (TIM) is used due to the lower thermal contact resistance (TCR). This offers a possibility to eliminate thermal grease in applications where electrical insulation is not required. With TIM both graphite and aluminum perform comparably. The graphite heat sink was less than half the weight of the aluminum one.
Re-mapping the internet: Bring the IXPs into play: www.inspire.edu.gr/ixp-map

The Internet topology is of high importance in designing networks and architectures, evaluating performance, and economics. Interconnections between domains (ASes), routers, and points of presence (PoPs), have been measured, analyzed, and modeled. However, existing models have some serious shortcomings, related to ease, accuracy and completeness of measurements, and limited applicability to emerging research areas. To this end, in this paper, we propose a novel approach towards capturing the inter-damain Internet topology. Motivated by the recent interest in the Internet eXchange Points (IXPs), we introduce a network graph model based on IXPs and their AS memberships. The proposed model aims to complement previous modeling efforts, shed light on unexplored characteristics of the Internet topology, and support new research directions. We also collect and make available Internet connectivity data, analyze main topological properties, and discuss application-related issues.
Attitude Toward E-Learning in South West Nigerian Universities : An Application of Technology Acceptance Model

The study examined the attitude of students towards e-learning in selected south-west Nigerian universities. Specifically the study looked at the relationship between attitude and e-learning with the application of Technology Acceptance Model (TAM). Questionnaire was used to collect data from a sample of 387 postgraduate and undergraduate students. Statistical techniques used for the analyses of data were frequency distribution, simple linear regression, One-Way ANOVA and paired T-test was used to test the hypotheses. Findings showed that students have a positive attitude towards e-learning because they find the system easy to use and useful for their course work. Also, attitude influences the intention to use an e-learning system.
Replicability is not Reproducibility:Nor is it Good Science

At various machine learning conferences, at various times, there have been discussions arising from the inability to replicate the experimental results published in a paper. There seems to be a wide spread view that we need to do something to address this problem, as it is essential to the advancement of our field. The most compelling argument would seem to be that reproducibility of experimental results is the hallmark of science. Therefore, given that most of us regard machine learning as a scientific discipline, being able to replicate experiments is paramount. I want to challenge this view by separating the notion of reproducibility, a generally desirable property, from replicability, its poor cousin. I claim there are important differences between the two. Reproducibility requires changes; replicability avoids them. Although reproducibility is desirable, I contend that the impoverished version, replicability, is one not worth having.
The Rabies Virus Interferon Antagonist P Protein Interacts with Activated STAT3 and Inhibits Gp130 Receptor Signaling

ABSTRACT Immune evasion by rabies virus depends on targeting of the signal transducers and activator of transcription 1 (STAT1) and STAT2 proteins by the viral interferon antagonist P protein, but targeting of other STAT proteins has not been investigated. Here, we find that P protein associates with activated STAT3 and inhibits STAT3 nuclear accumulation and Gp130-dependent signaling. This is the first report of STAT3 targeting by the interferon antagonist of a virus other than a paramyxovirus, indicating that STAT3 antagonism is important to a range of human-pathogenic viruses.
Effect of lifestyle interventions on cardiovascular risk factors among adults without impaired glucose tolerance or diabetes: A systematic review and meta-analysis

Structured lifestyle interventions can reduce diabetes incidence and cardiovascular disease (CVD) risk among persons with impaired glucose tolerance (IGT), but it is unclear whether they should be implemented among persons without IGT. We conducted a systematic review and meta-analyses to assess the effectiveness of lifestyle interventions on CVD risk among adults without IGT or diabetes. We systematically searched MEDLINE, EMBASE, CINAHL, Web of Science, the Cochrane Library, and PsychInfo databases, from inception to May 4, 2016. We selected randomized controlled trials of lifestyle interventions, involving physical activity (PA), dietary (D), or combined strategies (PA+D) with follow-up duration ≥12 months. We excluded all studies that included individuals with IGT, confirmed by 2-hours oral glucose tolerance test (75g), but included all other studies recruiting populations with different glycemic levels. We stratified studies by baseline glycemic levels: (1) low-range group with mean fasting plasma glucose (FPG) <5.5mmol/L or glycated hemoglobin (A1C) <5.5%, and (2) high-range group with FPG ≥5.5mmol/L or A1C ≥5.5%, and synthesized data using random-effects models. Primary outcomes in this review included systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and triglycerides (TG). Totally 79 studies met inclusion criteria. Compared to usual care (UC), lifestyle interventions achieved significant improvements in SBP (-2.16mmHg[95%CI, -2.93, -1.39]), DBP (-1.83mmHg[-2.34, -1.31]), TC (-0.10mmol/L[-0.15, -0.05]), LDL-C (-0.09mmol/L[-0.13, -0.04]), HDL-C (0.03mmol/L[0.01, 0.04]), and TG (-0.08mmol/L[-0.14, -0.03]). Similar effects were observed among both low-and high-range study groups except for TC and TG. Similar effects also appeared in SBP and DBP categories regardless of follow-up duration. PA+D interventions had larger improvement effects on CVD risk factors than PA alone interventions. In adults without IGT or diabetes, lifestyle interventions resulted in significant improvements in SBP, DBP, TC, LDL-C, HDL-C, and TG, and might further reduce CVD risk.
"I is an Other": An Exploration of the Development of Childhood and Adolescent Self-Concept

In this study I aim to obtain information about self-concept in children and adolescents, tracking the development of and approach to identity formation as mediated through linguistic and social developmental. By delivering the same timed written prompt to students in 2, 5, 8, and 11 grade, I investigate linguistic differences across age and gender, specifically language indicative of social awareness and emotional selfregulation. The prompt reads, “What do you think is your best personality quality? What is a quality that you’d like to change? Explain your responses. Give two examples from your life – one for each answer – in which you demonstrated each quality. ” The research also explores language as a route to understanding emotions, social relationships, perspective taking skills, and awareness of the other. The current study is mainly an exploration, meaning that while there are hypotheses about the outcome, the intent of what follows is not to necessarily to ‘prove’ or ‘disprove’, but rather to learn about childhood and adolescent self-representation. However, the overarching hypothesis is that there will be traceable changes in participants’ language use as they age; more specifically, there will be differences between the girls’ responses and the boys’ responses regardless of age, consistent with earlier findings (i.e. Newman, Groom, Handelman & Pennebaker, 2008). I also hypothesize certain similarities for each age group regardless of gender (i.e. Pennebaker