Miracle-dz/UniFAR-FTUs huggingface dataset:
Serum coenzyme Q10 concentrations in healthy men supplemented with 30 mg or 100 mg coenzyme Q10 for two months in a randomised controlled study

Serum coenzyme Q10 (Q10) concentrations were evaluated in healthy male volunteers supplemented with 30 mg or 100 mg Q10 or placebo as a single daily dose for two months in a randomised, double‐blind, placebo‐controlled study. Median baseline serum Q10concentration in 99 men was 1.26 mg/l (10%, 90% fractiles: 0.82, 1.83). Baseline serum Q10 concentration did not depend on age, while borderline significant positive associations were found for body weight and smoking 1–10 cigarettes/d. Supplementation with 30 mg or 100 mg Q10 resulted in median increases in serum Q10 concentration of 0.55 mg/l and 1.36 mg/l, respectively, compared with a median decrease of 0.23 mg/l with placebo. The changes in the Q10 groups were significantly different from that in the placebo group, and the increase in the 100 mg Q10 group was significantly greater than that in the 30∼mg Q10 group. The change in serum Q10concentration in the Q10 groups did not depend on baseline serum 10 concentration, age, or body weight.
Gay ghetto.

Gay people have claimed that there exist within major cities "gay ghettos", neighborhoods housing large numbers of homosexual men and women as well as gathering places where homosexual behavior is generally accepted, and have designated as such certain sections of Boston, New York, Chicago, San Francisco, and Los Angeles (Aiken, 1976, p. 27; Altman, 1971, p. 42; Brill, 1976, p. 27; Chicago Gay Liberation, 1970, pp. 3-4; Kantrowitz, 1975, p. 48; Nassberg, 1970, p. 1; Russo, 1976, p. 47; Shilts, 1977, p. 20; Whitmore, 1975, p. 45; Whittman, 1972, pp. 167-168). Sociologists have picked up the term, using it repeatedly in research (e.g., Humprheys, 1972a, pp. 80-81; Weinberg & Williams, 1974, p. 43). Typically, however, these authors offer no observations to support their use of the phrase. This paper analyzes the validity of "gay ghetto" as a sociological construct, limiting discussion to the male homosexual community.
Heavy Ion Characterization of Temporal-, Dual- and Triple Redundant Flip-Flops Across a Wide Supply Voltage Range in a 65 nm Bulk CMOS Process

In this paper, we investigate the single event upset (SEU) response of five D flip-flops (DFFs) employing temporal redundancy, dual redundancy, and triple modular redundancy (TMR), across a wide supply voltage range. The DFFs were designed and fabricated in a low-power commercial 65 nm bulk CMOS process and were tested using heavy ions with linear energy transfer (LET) between 5.1 MeV - cm2/mg and 99.1 MeV - cm2/mg. Results show an increasing SEU vulnerability with decreasing supply voltage, for most of the DFFs. Nevertheless, radiation tolerant topologies exhibit 14× to 1328× better SEU tolerance than a standard non-radiation tolerant DFF, depending on supply voltage and LET. The general observation is that at normal incidence, while taking the entire LET spectrum into account, the dual interlocked storage cell (DICE) DFF has the best SEU tolerance at supply voltages of 1 V and 0.5 V. At a supply voltage of 0.25 V, a temporal redundant DFF shows the best SEU tolerance, while the TMR DFF shows the best SEU tolerance at a supply voltage of 0.18 V. At supply voltages of 0.5 V and below, increasing the angle of incidence to 45 degrees can increase the SEU rate of the implemented DICE DFF by up to a factor of 22×, making it one of the most SEU sensitive DFFs. Furthermore, utilizing high drive strength components in temporally redundant DFFs can reduce the SEU sensitivity by a factor of 3× to 112×, compared to when standard drive strength components are used.
International business cycle co-movement: the role of FDI

This article investigates the relationship between FDI and business cycle synchronization in the period 1982 to 2011 for eight industrialized countries. We find that more synchronized business cycles are associated with stronger FDI relations in the period 1995 to 2011, but not before 1995. More intensive FDI links are also associated with a greater vulnerability to lagged output spillovers from abroad. Our findings suggest that FDI has become a separate channel through which economies may affect each other and that FDI stocks are now an essential aspect of economic interdependence.
Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows

Energy balance was assessed during the first 13 weeks postpartum in 497 primiparous Holstein cows and the relationship with reproductive performance was investigated. A significant association was observed between body condition score (BCS) and a number of reproductive traits, including conception at first artificial insemination (AI), number of inseminations per conception, calving to conception and calving intervals, percentage pregnant by the end of a 305-day lactation and incidence of metritis. The BCS from calving to week 9 (before the first AI) appeared to adequately predict future reproductive performance as it was correlated with calving interval, conception at first AI, metritis and percentage pregnant by the end of a 305-day lactation. Plasma β-hydroxybutyrate (BHB) concentrations were correlated with the latter trait only, whereas non-esterified fatty acid concentrations were not associated with reproductive performance.
A three year herd health and management program on thirty Dutch dairy farms. II. Culling strategy and losses caused by forced replacement of dairy cows.

Cows are culled at a relatively low age, which causes considerable economic loss. The annual culling rate in the Netherlands has increased from 18.8 per cent in 1951 to 25-30 per cent of the average number of cows in more recent years. The productive life is now about 3.5 years. On the thirty farms of the program group and thirty-one farms of the control group, the main reasons for culling were reproductive failure followed by mastitis and teat injuries. About 60 per cent of culling was due to health problems, the other 40 per cent to low productive capacity, old age, poor workability etc. The annual culling rate varied per farm per year but also per month. The moment of culling in the current lactation, the slaughter value and the age differed per reason. The calculated loss of forced replacement consists of reduction in both production prior to culling and slaughter value. Additionally, there is an idle production period due to lack of an immediate replacement. The biggest loss is caused by lost future income. There was a considerable difference per farm in the loss caused by culling for health problems. A low culling rate due to health problems was associated with longer longevity and a relatively lower loss. Tangible effects due to changes in the farm culling policy may not be evident for some years. The reduction in loss of culling in the program farms compared with the controls was small because the duration (2 1/2 years) of the herd health and management program was too short. (ABSTRACT TRUNCATED AT 250 WORDS)
Deep Mixture of Linear Inverse Regressions Applied to Head-Pose Estimation

Convolutional Neural Networks (ConvNets) have become the state-of-the-art for many classification and regression problems in computer vision. When it comes to regression, approaches such as measuring the Euclidean distance of target and predictions are often employed as output layer. In this paper, we propose the coupling of a Gaussian mixture of linear inverse regressions with a ConvNet, and we describe the methodological foundations and the associated algorithm to jointly train the deep network and the regression function. We test our model on the head-pose estimation problem. In this particular problem, we show that inverse regression outperforms regression models currently used by state-of-the-art computer vision methods. Our method does not require the incorporation of additional data, as it is often proposed in the literature, thus it is able to work well on relatively small training datasets. Finally, it outperforms state-of-the-art methods in head-pose estimation using a widely used head-pose dataset. To the best of our knowledge, we are the first to incorporate inverse regression into deep learning for computer vision applications.
Evaluation of Dental Anxiety in Parents Accompanying their Children for Dental Treatment

Objective: To evaluate the anxiety level of parents accompanying their children for the dental treatment. Materials & Method: Dental Anxiety Scale-Revised (DAS-R) questionnaire was filled by 101 subjects (53 females and 48 males) visiting the dental department for their children’s dental treatment. Result: 62.4 % parents accompanying their children had no or low anxiety levels and 9.9% and 5.9% showed high to severe anxiety levels respectively. There was no statistical significant difference seen between the anxiety levels in male and female parents. Conclusion: 37.6 % parents accompanying their children to the dentist showed moderate to severe anxiety levels with no significant difference seen in the overall anxiety levels of mothers and fathers.
Empirical examination of diversification strategies in business groups

Purpose – To examine the influence of direction of related and unrelated diversification on business groups' performance in emerging markets.Design/methodology/approach – The paper empirically examines a hypothesis based on the theoretical perspective of the resource‐based view. The paper builds a regression model with the dependent variable Tobin's q as a proxy for group/firm value and various other performance measures (derived from financial data) that theory suggests influences firm value. It examines the differences in firm value measure across three classes, namely related‐diversified business groups, unrelated‐diversified business groups and standalone firms.Findings – The results confirm the findings of prior research which suggests that group affiliation is beneficial in emerging markets. However, as a departure, the main finding is that the benefits of group affiliation are not equally available to related‐diversified and unrelated diversified groups.Research limitations/implications – This rese.
Cool Enough for School: Second Version of Google Glass Rated by Children Facing Challenges to Social Integration as Desirable to Wear at School

Background On July 18th, 2017, X, a subsidiary of Alphabet Inc. announced the successor to Google Glass. Glass Enterprise Edition could function as an assistive technology for autism spectrum disorder (ASD), yet its acceptability, desirability, and the willingness of children with ASD to wear it, are not known. The authors review key issues surrounding smartglasses and social communication, child development, and the school environment. Methods The smartglasses were evaluated by eight children with ASD, who ranged from moderately non-verbal to verbal, in the context of whether they would desire to wear it and use it as an assistive device each day at their respective schools. Children represented the full range of school ages (6 – 17yrs). Results All eight children responded that they would want to wear and use Glass Enterprise Edition at school. Additionally, all eight parents said their child had fun during the testing session, and six of eight parents said the experience went better than they had thought. Conclusion The results show that children with ASD are willing to use Glass Enterprise Edition in a school setting, highlighting its desirability and social acceptability in this population, as well as its future potential as an assistive technology.
The prevalence of obstructive sleep apnea in patients with difficult-to-treat asthma.

OBJECTIVES Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population and can complicate asthma management. The aim of this study was to evaluate the presence of OSA in patients with difficult-to-treat asthma (DTA) and to investigate the sleep quality in these patients. METHODS Patients with DTA were recruited from the adult allergy clinic of a tertiary care hospital. After completing the Sleep Questionnaire and Epworth Sleepiness Scale, all participants underwent overnight polysomnography. The demographic and asthma severity assessments included the following measures: the age at diagnosis, duration of illness, smoking and atopy status, results of pulmonary function tests, number of asthma control medications used, and number of hospitalizations and emergency room visits because of asthma and analgesic hypersensitivity according to apnea-hypopnea index (AHI) scores. RESULTS We analyzed 47 (M:9/F:38) DTA patients with a mean age of 48.74±9.45 years. The mean duration of asthma was 9.17±6.5 years. Twenty-four (51.1%) patients were atopic. The analgesic hypersensitivity rate was 27.7%. Fourteen patients (29.8%) were former smokers and 2 patients were current smokers. Sleep quality was impaired in all patients. Thirty-five patients (74.5%) had OSA, 11 of whom had mild OSA, and 24 patients had moderate-severe OSA. The presence of OSA was not statistically correlated with asthma characteristics. CONCLUSION The study showed that there is a remarkably high prevalence of OSA in DTA. Although no statistically significant relationship between the presence of OSA and clinical asthma characteristics was identified, all DTA patients should be assessed for OSA.
Following the Organizing Over Time: Focus on the Concept of Compromises

This paper deals with the concept of compromise in organization studies. The concept of compromise is often mobilized in discourses. Nevertheless, it seems difficult to comprehend this concept, while it can help us to enhance our understanding about organization structuring. The aim is to propose a conceptual framework in order to understand the shaping of compromise, and the roles of compromises in organization. The main contribution is in the understanding of concept of compromise both as a process and a state. Compromise also understands itself as an actant mobilized and redefined in practice by actors to mediate their interaction and coordinate themselves. Thus, compromise enables and constrains interaction because it carries on irreversibility in the organizational process. From a case study based on the development of an Information System for Human Resource Management in a bank during the financial crisis, I illustrate the conceptual framework, and I discuss three roles and effects of compromises in organizational process: the importance of the first compromise in organizational process, the compromise as an ongoing update equilibrium between concession and gift, and the materialization of compromise to objective modalities.
p53, mdm2, EGFR, and msh2 expression in paired initial and recurrent glioblastoma multiforme

Background: The clinical course of glioblastoma multiforme is characterised by invasive growth and regular recurrence. Many genetic alteration have been identified in the genesis of the disease. However, information about immunohistochemical expression in recurrent lesions is sparse. Objectives: To determine (1) whether the p53/mdm2/EGFR/msh2 expression pattern differs in initial v recurrent glioblastoma multiforme; (2) whether a possible change in expression correlates with prognostic variables (progression-free survival time, total survival time); and (3) whether chemotherapy in addition to surgery and radiotherapy influences the p53/mdm2/EGFR/msh2 expression profile. Methods: 27 patients were studied. They met the following criteria: histologically confirmed diagnosis of glioblastoma multiforme (WHO IV); total tumour resection at initial craniotomy; at least one re-craniotomy for glioblastoma multiforme recurrence; age 21 years or older. All underwent radiotherapy of at least 54 Gy, and 17 received additional chemotherapy. Immunohistochemical staining of initial tumours and recurrences was done with the following monoclonal antibodies: anti-p53 (DO-1), anti-mdm2 (IF-2), anti-EGFR (H11), and anti-msh2 (AB-1). Results: In comparison with the initial tumour, recurrent lesions were characterised by reduced expression of p53 (p < 0.0001) and msh2 (p = 0.0012), while the numbers of mdm2 (p = 0.02), EGFR (p < 0.0001), and msh2 positive specimens (p < 0.0001) were reduced. Chemotherapy was associated with reduced msh2 expression (p < 0.0001). Immunohistochemical variables were not associated with patient survival. Conclusions: There are significant differences in the p53/mdm2/EGFR/msh2 expression patterns in initial v recurrent glioblastoma multiforme. There may be interactions between chemotherapy and changes in the msh2 expression.
Lp(a) levels and atherosclerotic vascular disease in a sample of patients with familial hypercholesterolemia sharing the same gene defect.

There is considerable variation in the severity of cardiovascular disease among patients with familial hypercholesterolemia (FH). Some reports have suggested that plasma lipoprotein(a) [Lp(a)] levels may explain such variation and that FH subjects deficient in LDL receptors, especially those with coronary heart disease, tend to have elevated Lp(a) levels. We have investigated the possible role of the LDL receptor in determining plasma Lp(a) levels in genetically homogeneous FH population and the contribution of Lp(a) to cardiovascular risk. A total of 98 FH subjects and 66 healthy first- and second-degree relatives from 30 families with FH due to the French-Canadian > 10-kilobase deletion of the LDL receptor gene were studied. A reference group of 392 normolipidemic French-Canadian participants in a Heart Health Survey was used for comparison. FH subjects were subdivided into subsets of 63 individuals free from atherosclerotic vascular disease (AVD) and 35 individuals with AVD. A complete cardiovascular evaluation was performed, and plasma lipid, lipoprotein, and Lp(a) levels were measured in all subjects in the absence of medication. Apolipoprotein (a) [apo(a)] phenotype was determined in 112 of FH and non-FH subjects. The log-transformed values for plasma Lp(a) were not significantly different among the three groups: 0.98 +/- 0.54 (mean +/- SD) in FH subjects with AVD, 0.89 +/- 0.51 in FH subjects without AVD, and 0.82 +/- 0.64 in their relatives. The distribution of the apo(a) phenotypes did not differ between the FH and non-FH groups. Comparison of two age- and sex-matched subgroups of FH subjects, with and without AVD, failed to show any differences in Lp(a) level. However, mean Lp(a) log values in the reference group (n = 392) were significantly lower than values obtained for the total FH group (0.79 +/- 0.57 versus 0.92 +/- 0.52, respectively; P < .05) but were not different from those of the unaffected family members. Thus, in our sample, the LDL receptor appears not to influence plasma Lp(a) levels; rather, these levels reflect shared apo(a) genes. The cardiovascular risk in this group of subjects with FH was related to age, male sex, total and LDL cholesterol, and higher apoB but not Lp(a) levels.
Testing for Short Termism in the UK Stock Market: A Comment

In the November I 993 issue of thisJOURNAL, David Miles estimates, and tests for, the presence of short-termism in the United Kingdom using data from I980 to I988 based on a sample of 477 non-financial firms. He modestly declines to claim that he has detected the presence of shorttermism but concludes that: 'those who believe it does not exist do need to explain something about the operation of security markets which makes longerterm cash flow appear to be discounted at much higher rates than shorter-term flows. ' The purpose of this note is to provide a model which gives such an explanation; we shall also show that such a model is consistent with the empirical realities of the early i980s. J We believe that the Miles paper has two serious defects. The first is the assumption that the risk premia per unit time varies across firms but is constant through time: over/under discounting is then detected relative to this base. To quote Miles:
Detection of low amplitude fetal QRS complexes

The significance of the most important operations performed by the noninvasive systems for fetal heart rate determination is investigated. The method of template subtraction for maternal ECG suppression is compared to the method based on independent component analysis. The QRS detector based on the classical slope-responsive preprocessing competes with the one that employs normalized matched filtering for QRS enhancement. A small database containing the four-channel abdominal ECG signals with the marked positions of the fetal QRS complexes is prepared to enable the investigations. The performed experiments show the factors that have the greatest impact on the results of the fetal QRS detection, and an effective approach to cope the problem is proposed.
A 920-Kilometer Optical Fiber Link for Frequency Metrology at the 19th Decimal Place

Synchronize Watches Time standards based on the energy-level transitions of atoms and ions provide the most accurate and precise methods of time keeping. Measurements made in one laboratory and in another must be done with clocks that have been synchronized and calibrated to ensure that the same measurement is being made. Such clocks, however, are not particularly mobile and are housed in national metrology labs. Predehl et al. (p. 441; see the Perspective by Warrington) linked two optical clocks separated by over 900 kilometers using optical fiber to show that the clocks can be synchronized, with the clocks showing a frequency stability better than 3.7 × 10−19. Such long-distance synchronization should allow for tests of fundamental physics, such as general relativity and quantum electrodynamics. A long-distance fiber network is used to synchronize two optical clocks with high precision. Optical clocks show unprecedented accuracy, surpassing that of previously available clock systems by more than one order of magnitude. Precise intercomparisons will enable a variety of experiments, including tests of fundamental quantum physics and cosmology and applications in geodesy and navigation. Well-established, satellite-based techniques for microwave dissemination are not adequate to compare optical clocks. Here, we present phase-stabilized distribution of an optical frequency over 920 kilometers of telecommunication fiber. We used two antiparallel fiber links to determine their fractional frequency instability (modified Allan deviation) to 5 × 10−15 in a 1-second integration time, reaching 10−18 in less than 1000 seconds. For long integration times τ, the deviation from the expected frequency value has been constrained to within 4 × 10−19. The link may serve as part of a Europe-wide optical frequency dissemination network.
Production-Line Balances for Mixed-Model Lines

This paper considers the problem of mixed-model assembly-line balancing. First, the balance problem is formulated, and some of the difficulties of achieving effective balances in practice are noted. Next, balance procedures designed to obtain expeditious computer solutions of large-scale mixed-model balances are presented, and results obtained for a small-scale balance by a program incorporating these procedures are discussed. Effect on line performance is considered, and an estimate is made of the computer effort required to achieve a balance for a large-scale assembly operation. Finally some general conclusions are presented.