Miracle-dz/UniFAR-FTUs huggingface dataset:
Student Perceptions of University Physical Activity Instruction Courses Taught Utilizing Sport Education.

Limited research exists on effective teaching methods in university physical activity instruction (PAI) program courses. The purpose of this study was to evaluate PAI courses taught utilizing a sport education curriculum and instructional model. The Individual Development and Educational Assessment (IDEA) teaching evaluation was administered to students (n = 306) in PAI classes during the last week of each 10 and one-half week course. The IDEA includes student self-evaluations of progress on course objectives as well as evaluations of teaching approaches used by course instructors: stimulating student interest (SSI), fostering student collaboration (FSC), establishing rapport (ER), encouraging student involvement (ESI), and structuring classroom experiences (SCE). The instrument also includes overall ratings of the course and the teacher. Results indicated that student ratings of progress on course objectives were high (M = 4.20, on a 5-point Likert scale). Evaluations of the teaching approaches used by course instructors were also high (SSI = 4.44, FSC = 4.50, ER = 4.36, ESI = 4.04, SCE = 4.54) and compare favorably to published norms in the PE discipline. Overall ratings of the courses (M = 4.34) and the instructors (M = 4.63) also compared favorably to published norms (M = 4.16, M = 4.33, respectively). This study demonstrates that PAI courses taught utilizing a sport education teaching model are effective in terms of both student self-evaluations of progress on course objectives and ratings of teaching effectiveness.
Relationship between circulating n-3 fatty acid concentrations and endothelial function in early adulthood.

AIMS Fish consumption is inversely associated with cardiovascular mortality, presumably because of n-3 fatty acids in fish. Whether the protection of n-3 fatty acids extends beyond clinical coronary disease to influence the early vascular biology of atherosclerosis remains unclear. This study determined whether circulating levels of n-3 fatty acids are associated with vascular endothelial function in early adulthood. METHODS AND RESULTS Three hundred and twenty-six adults (157 males, 169 females, aged 20 to 28 years) had high-resolution ultrasound measurements of flow-mediated brachial artery dilatation (FMD) (endothelium-dependent) and arterial response to glyceryl trinitrate (endothelium-independent). Levels of the n-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid in plasma and erythrocyte membranes of subjects were measured. n-3 Fatty acid levels were not related to vascular function in the whole group. In smokers, however, n-3 fatty acids were positively related to flow-mediated dilatation (plasma DHA vs. FMD: 0.045 mm. %(-1), 95% CI 0.011 to 0.079, P=0.01). Flow-mediated dilatation was also associated with n-3 fatty acid levels in subjects in the top third of the insulin, glucose and triglyceride distributions. CONCLUSION In young smokers and those with higher fasting insulin, glucose or triglyceride concentrations (factors associated with endothelial dysfunction), n-3 fatty acid levels were positively associated with flow-mediated dilatation. This raises the possibility that physiological levels of circulating n-3 fatty acids may protect the endothelium from early adulthood.
Patch-Collaborative Spectral Surface Denoising

We present a new framework for denoising of point clouds by patchcollaborative spectral analysis. A collaborative generalization of each surface patch is defined, combining similar patches from the surface. The Laplace-Beltrami operator of the collaborative patch is then used to selectively smooth the surface in a robust manner that can gracefully handle high levels of noise. The resulting denoising algorithm competes favorably with stateof-the-art approaches, and extends patch-matching algorithms from the image processing domain to point clouds of arbitrary sampling. We demonstrate the accuracy and noise-robustness of the proposed algorithm on standard benchmark models as well as range scans, and compare it to existing methods for point cloud denoising.
Predictors of duloxetine adherence and persistence in patients with fibromyalgia

Objectives Adherence to medication for the treatment of fibromyalgia (FM) is predictive of lower overall health-care costs, and thus a lower burden on both patients and providers. The objectives of this study were to examine the predictors of adherence to and persistence with duloxetine therapy among commercially insured FM patients, and to identify subgroups of patients with high duloxetine persistence and adherence. Study design This cross-sectional, retrospective study analyzed medical and pharmacy records over 1 year for patients in the US aged 18–64 years with FM who initiated (no prior 90-day use) duloxetine treatment in 2008. Methods Adherence to duloxetine was measured by medication possession ratio (MPR), with high adherence defined as MPR ≥ 0.8. Persistence was defined as the duration of therapy from the index date to the earliest of: the ending date of the last prescription, the date of the first gap of >15 days between prescriptions, or the end of the study period (12 months). Demographic and clinical predictors of adherence were examined via multiple logistic regression (MLR), and subgroups of duloxetine-persistent and -adherent patients were identified using classification and regression trees (CART). Results Among 4660 duloxetine patients, 33% achieved high adherence. Factors associated with high adherence from MLR included older age, North Central and Northeast regions, prior venlafaxine, pregabalin, selective serotonin reuptake inhibitor (SSRI), or other antidepressant use, or comorbid dyslipidemia or osteoarthritis (all P < 0.05). CART analysis revealed that patients with prior antidepressant use, aged ≥46, or prior osteoarthritis had higher MPR (all P < 0.05), and patients aged ≥45 with a history of SSRI, venlafaxine, or anticonvulsant use had longer duration of therapy (all P < 0.05). Conclusions Patients with high adherence to and persistence with duloxetine were significantly older and had prior antidepressant use.
Age Diversity, Age Discrimination Climate and Performance Consequences - a Cross Organizational Study

This paper deals with the emergence of perceived age discrimination climate on the company level and its performance consequences. In this new approach to the field of diversity research, we investigated (a) the effect of organizational-level age diversity on collective perceptions of age discrimination climate that (b) in turn should influence the collective affective commitment of employees, which is (c) an important trigger for overall company performance. In a large-scale study that included 128 companies, a total of 8,651 employees provided data on their perceptions of age discrimination and affective commitment on the company level. Information on firm-level performance was collected from key informants. We tested the proposed model using structural equation modeling (SEM) procedures and, overall, found support for all hypothesized relationships. The findings demonstrated that age diversity seems to be related to the emergence of an age discrimination climate in companies, which negatively impacts overall firm performance through the mediation of affective commitment. These results make valuable contributions to the diversity and discrimination literature by establishing perceived age discrimination on the company level as a decisive mediator in the age diversity/performance link. The results also suggest important practical implications for the effective management of an increasingly age diverse workforce.
Development of economical vehicle model for pedestrian-friendly front-end profile study

An economical and deformable, hybrid model is developed for studying the effect of vehicle geometry on pedestrian fall kinematics and associated head injury. A simplified structure consisting of finite element surfaces and a Multi-body windshield is built using a series of iterative and no-iterative steps. The primary focus is not the stiffness characteristics of the structure but rather the fall pattern and kinematics data of the pedestrian due solely to the vehicle front-end shape.Comprehensive validation is carried out wherbey the fidelity of the model is reviewed for pedestrian crash kinematics and injury criteria as well as piecewise vehicle parts impact tests. The model is shown to hold up acceptably well against benchmarked values especially for the former, whereby very close head injury criteria values are obtained at identical impact locations. The model's notable features are its economical computational processing time and eases of modification.
Defense Against Spoofed IP Traffic Using Hop-Count Filtering

IP spoofing has often been exploited by Distributed Denial of Service (DDoS) attacks to: 1)conceal flooding sources and dilute localities in flooding traffic, and 2)coax legitimate hosts into becoming reflectors, redirecting and amplifying flooding traffic. Thus, the ability to filter spoofed IP packets near victim servers is essential to their own protection and prevention of becoming involuntary DoS reflectors. Although an attacker can forge any field in the IP header, he cannot falsify the number of hops an IP packet takes to reach its destination. More importantly, since the hop-count values are diverse, an attacker cannot randomly spoof IP addresses while maintaining consistent hop-counts. On the other hand, an Internet server can easily infer the hop-count information from the Time-to-Live (TTL) field of the IP header. Using a mapping between IP addresses and their hop-counts, the server can distinguish spoofed IP packets from legitimate ones. Based on this observation, we present a novel filtering technique, called Hop-Count Filtering (HCF)-which builds an accurate IP-to-hop-count (IP2HC) mapping table-to detect and discard spoofed IP packets. HCF is easy to deploy, as it does not require any support from the underlying network. Through analysis using network measurement data, we show that HCF can identify close to 90% of spoofed IP packets, and then discard them with little collateral damage. We implement and evaluate HCF in the Linux kernel, demonstrating its effectiveness with experimental measurements
(Work in Progress) Is this a privacy incident? Using News Exemplars to Study End User Perceptions of Privacy Incidents

A clear and efficient process for responding to privacy incidents is widely viewed as necessary for a strong privacy program. In addition, analysis of privacy incidents is advocated to understand risk trends. Both incident response and analysis require an actionable definition of privacy incident, which is challenging to derive given that privacy attitudes vary by culture and context, resulting in variation in incident manifestation. We present a first study of end user understanding of the term “privacy incident” with 482 Amazon Mechanical Turk users. Our study uses a variety of news exemplars, many of which concern the privacy-related concepts of data collection, storage, and usage. We find that although participants appear to closely tie sensitive data collection and usage to privacy, they often conflate privacy and security and are more inclined than privacy law to view perceived or anticipated privacy issues as grounds for an incident. Our study suggests that there is some degree of schism between end user conceptions of privacy and the views of industry and government.
An Integrated View of Personal, Relational, and Organizational Resources: How They Ignite Creative Behavior at Work

Individual creativity is an important antecedent of organizational innovation (Amabile, 1988; Woodman, Sawyer, and Griffin, 1993; Shalley, Zhou, & Oldham 2004). In the current hypercompetitive, global work environment, more managers recognize that in order to remain competitive, they need their employees to be engaged in their work and demonstrate creative behaviors (Mumford, Scott, Gaddis, & Strange, 2002). Therefore, it is important to understand the mechanisms by which individuals demonstrate creative behaviors at work, especially by utilizing the resources that are available to them to facilitate creativity and overcoming the demands that hinder their creative behavior at work. Employing the Job Demands-Resources (JD-R) model, which states job demands and resources can be used to predict motivational processes, and consequently organizational outcomes, I suggested that personal, relational, and organizational resources will promote creative behavior via their influence on intrinsic motivation. In this study, personal resources are comprised of creative self-efficacy and resilience whereas bonding and bridging ties represent the relational resources. Perceived organizational support for creativity comprises the organizational resource. Finally, I examined the moderating influence of a demand in the form of role overload; I proposed that role overload will moderate the relationship between resources and intrinsic motivation. Given the current tough economic times, role overload seems to have become an endemic feature of an employee's work life, and as such can be a meaningful job demand. I proposed that role overload will attenuate the positive impact of personal, relational, and organizational resources positive influence on intrinsic motivation, which in turn lead to creative behavior. In order to test the hypothesized relationships, I collected data from a Fortune 100 organization; 126 employees from that organization filled out the survey and due to missing data 120 surveys were usable. I also collected 22 employee-supervisor dyads using existing validated scales for both groups. I used multiple regression analysis to analyze the data. Results indicated that both perceived organizational support and bridging ties are motivational resources. In addition, creative self-efficacy and bridging ties influenced creative behavior. Moreover, the results revealed that the relationship between bridging ties and creative behavior is mediated by intrinsic motivation. Finally, I observed that employees with bonding ties who experienced high role overload tended to have lower levels of intrinsic motivation. In summary, my dissertation is an attempt to contribute to the creativity literature and Job Demands-Resources (JD-R) model. Specifically, this dissertation contributes to creativity literature by unifying several prominent resources in one study and examining their simultaneous influence on intrinsic motivation, which in turn was found to influence creative behavior. Furthermore, I introduced and…
Molecular Ca 2 Ion Permeability and Single-Channel Properties of the Metabotropic Slow EPSC of Rat Purkinje Neurons

The slow EPSC (sEPSC) of cerebellar parallel fiber3 Purkinje neuron synapses is mediated by metabotropic glutamate receptor type 1 (mGluR1) activation of nonselective cation channels. Here, the channel properties were studied with uniform calibrated photorelease of L-glutamate with ionotropic receptors blocked, allowing isolation of postsynaptic processes, or with parallel fiber stimulation or mGluR1 agonist application. Evoked current and fluorescence from Ca 2 indicators were recorded. Noise analysis of the mGluR1 current gave a single-channel conductance of 0.6 pS and showed low open probability at maximal mGluR1 activation. Similar small single-channel conductances were obtained with the mGluR1 agonist (S)-dihydroxyphenylglycine, with parallel fiber or climbing fiber stimulation. The mGluR1 current fluctuations were unaffected by potassium channel blockers. Photoreleased L-glutamate triggered a Ca 2 concentration increase in the distal dendrites with a time course similar to that of the mGluR1 current. The proximal dendritic and somatic Ca 2 changes were delayed with respect to the current. Ca 2 channel blockers and the phospholipase C inhibitor 1-[6-[((17 )-3methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-1H-pyrrole-2,5-dione, which inhibits mGluR1-activated intracellular Ca 2 release, did not prevent the dendritic Ca 2 concentration increase. Polyamine naphthylacetyl spermine and cationic adamantanes that block the pore of the channel were used to vary the mGluR1 current over a wide range in each cell but still at maximal mGluR1 activation. The Ca 2 influx was inhibited in parallel with the current. The results show that the mGluR1-activated current and the sEPSC are attributable to small-conductance, low-open probability Ca 2 -permeable cation channels that will mediate spine-specific Ca 2 influx during the parallel fiber sEPSP.
Ieee Geoscience and Remote Sensing Letters 1 a Spatio–temporal Pixel-swapping Algorithm for Subpixel Land Cover Mapping

—The aim of this letter is to present a spatio–temporal pixel-swapping algorithm (STPSA), based on conventional pixel-swapping algorithms (PSAs), in which both spatial and temporal contextual information from previous land cover maps or observed samples are well integrated and utilized to improve subpixel mapping accuracy. Unlike conventional pixel-swapping algorithms, STPSA is capable of utilizing prior information, which was previously ignored, to predict the attractiveness based on pairs of subpixels. This algorithm involves three main steps and operates in an iterative manner: 1) it predicts the maximum and minimum attractiveness of each pair of pixels; 2) ranks the swapping scores based on the attractiveness of all the pairs; and 3) swaps the locations of the pair of pixels with a maximum score to increase the objective function. Experiments with actual satellite images have demonstrated that the proposed algorithm performs better than other algorithms. In comparison, the proposed STPSA's better performance is due to the fact that prior information used in other algorithms is restricted to a percentage level rather than the real subpixel level.
The activated NF-kappaB-Snail-RKIP circuitry in cancer regulates both the metastatic cascade and resistance to apoptosis by cytotoxic drugs.

Premalignant cells acquire a series of genetic and epigenetic changes that are responsible for cell proliferation in the absence of growth factors. It is not yet defined how the initial steps of the invasive metastatic cascade are acquired. New insights into the initial steps of the metastatic process were revealed by a set of regulators that induced the differentiation program termed "the epithelial to mesenchymal transition (EMT). " EMT is regulated by distinct transcription factors such as Snail, Slug and TWIST. Overexpression of Snail in cancer is responsible, in part, for the induction of EMT through the downregulation of E-cadherin and cytokeratins and the induction of mesenchymal protein expression such as vimentin, fibronectin, N-cadherin, metalloproteases, and invasiveness. In contrast, the metastatic suppressor Raf-kinase inhibitor protein (RKIP) is poorly expressed in primary cancers and absent in various metastatic cancers. RKIP inhibits NF-kappaB activity through direct interaction with NIK and TAK1. Snail was shown to suppress RKIP transcription and expression, and Snail is transcriptionally regulated by NF-kappaB. Thus, a circuitry is developed in which overexpression of Snail in tumors inhibits RKIP and induces EMT. In addition, NF-kappaB, Snail, and RKIP have been shown to regulate tumor-cell resistance to apoptotic stimuli. Inhibition of NF-kappaB and Snail and induction of RKIP sensitize resistant tumor cells to apoptosis by various chemotherapeutic and immunotherapeutic drugs. Furthermore, the ratio of Snail over RKIP expression in tumor cells is of prognostic significance and predicts response to cytotoxic therapies. Thus, pharmacological agents regulating the RKIP-NF-kappaB-Snail loop can be used as both sensitizing agents for apoptosis when combined with cytotoxic therapies as well as inhibitors of metastasis.
Transition-Based Dependency Parsing with Stack Long Short-Term Memory

This work was sponsored in part by the U. S. Army Research Laboratory and the U. S. Army Research Office/nunder contract/grant number W911NF-10-1-0533, and in part by NSF CAREER grant IIS-1054319. /nMiguel Ballesteros is supported by the European Commission under the contract numbers FP7-ICT-610411 (project MULTISENSOR) and H2020-RIA-645012 (project KRISTINA).
Unlocking Controllable-Polarity Transistors Opportunities by Exclusive-OR and Majority Logic Synthesis

For more than four decades, Complementary Metal-Oxide-Semiconductor (CMOS) Field Effect Transistors (FETs) have been the baseline technology for implementing digital computation systems. CMOS transistors natively implement Not-AND (NAND)- and Not-OR (NOR)-based logic operators. Nowadays, we observe a trend towards devices with an increased set of logic capabilities, i.e., with the ability to realize in a compact way specific logic operators as compared to the standard CMOS. In particular, controllable-polarity devices enable a native and compact realization of eXclusive-OR (XOR)- and MAJority (MAJ)- logic functions, and open a large panel of opportunities for future high-performance computing systems. However, main current logic synthesis tools exploit algorithms using NAND/NOR representations that are not able to fully exploit the capabilities of novel XOR- and MAJ-oriented technologies. In this paper, we review some recent work that aims at providing novel logic synthesis techniques that natively assess the logic capabilities of XOR- and MAJ-operators.
Somatic symptom presentations in women with fibromyalgia are differentially associated with elevated depression and anxiety

This study examined whether depression and anxiety differentially relate to fatigue, sleep disturbance, pain catastrophizing, fear of movement, and pain severity in women with fibromyalgia. Baseline data from the Fibromyalgia Activity Study with Transcutaneous Electrical Nerve Stimulation were analyzed. Of 191 participants, 50 percent reported high anxiety and/or depression (17% high anxiety, 9% high depression, and 24% both). Fatigue and sleep impairment were associated with high depression (p < 0.05). Pain severity, pain catastrophizing, and fear of movement were associated with high anxiety and high depression (p < 0.05). Possible implications for underlying mechanisms and the need for targeted treatments are discussed.
Chicken nonmuscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides

Two different mRNAs encoding two different nonmuscle myosin heavy chains (MHCs) of approximately 200 kD have been identified in chicken nonmuscle cells, in agreement with the results of Katsuragawa et al. (Katsuragawa, Y., M. Yanagisawa, A. Inoue, and T. Masaki. 1989. Eur. J. Biochem. 184:611-616). In this paper, we quantitate the content of mRNA encoding the two MHCs in a number of different tissues using RNA blot analysis with two specific oligonucleotide probes. Our results show that the relative content of mRNA encoding MHC-A and MHC-B differs in a tissue-dependent manner. Thus the ratio of mRNA encoding MHC-A versus MHC-B varies from greater than 9:1 in spleen and intestinal epithelial cells, to 6:4 in kidney and 2:8 in brain. The effect of serum on MHC mRNA expression was studied in serum-starved cultures of chick embryo fibroblasts. Serum stimulation results in a threefold increase in the mRNA encoding MHC-A and a threefold decrease in mRNA encoding MHC-B. Using SDS polyacrylamide gels, we have separated two nonmuscle MHC isoforms (198 and 196 kD) that can be distinguished from each other by two-dimensional peptide mapping of chymotryptic digests. We provide preliminary evidence that the MHC-A mRNA encodes the 196-kD polypeptide and that the MHC-B mRNA encodes the 198-kD polypeptide.