Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of Sustained Hemodiafiltration with Acetate-Free Dialysate and Continuous Venovenous Hemodiafiltration for the Treatment of Critically Ill Patients with Acute Kidney Injury

We conducted a prospective, randomized study to compare conventional continuous venovenous hemodiafiltration (CVVHDF) with sustained hemodiafiltration (SHDF) using an acetate-free dialysate. Fifty critically ill patients with acute kidney injury (AKI) who required renal replacement therapy were treated with either CVVHDF or SHDF. CVVDHF was performed using a conventional dialysate with an effluent rate of 25 mL·kg−1 · h−1, and SHDF was performed using an acetate-free dialysate with a flow rate of 300−500 mL/min. The primary study outcome, 30 d survival rate was 76.0% in the CVVHDF arm and 88.0% in the SHDF arm (NS). Both the number of patients who showed renal recovery (40.0% and 68.0%, CVVHDF and SHDF, resp.; P < .05), and the hospital stay length (42.3 days and 33.7 days, CVVHDF and SHDF, resp.; P < .05), significantly differed between the two treatments. Although the total convective volumes did not significantly differ, the dialysate flow rate was higher and mean duration of daily treatment was shorter in the SHDF treatment arm. Our results suggest that compared with conventional CVVHDF, more intensive renal support in the form of post-dilution SHDF with acetate-free dialysate may accelerate renal recovery in critically ill patients with AKI.
HRM practices, impersonal trust and organizational innovativeness

Purpose – Organizational processes that create conditions to facilitate employee innovativeness have become topical due to the constant demand for organizations to renew themselves. Research shows that human resource management (HRM) practices can been used to create such conditions, but also the important complementary role of organizational trust has been highlighted in this context. In particular, earlier studies have mostly focused on the concept of interpersonal trust. However, impersonal trust (the individual employee’s expectations about the employer organization’s capability and fairness) has recently been suggested to be an equally or even more relevant facilitator supporting the effect of HRM practices on organizational innovativeness. The paper aims to discuss these issues. Design/methodology/approach – The hypotheses were tested with two large-scale quantitative studies from the forestry and information and communication technology industries in Finland. Structural equation modelling (with LIS.
Incorporating Climate Change and Exotic Species into Forecasts of Riparian Forest Distribution

We examined the impact climate change (CC) will have on the availability of climatically suitable habitat for three native and one exotic riparian species. Due to its increasing prevalence in arid regions throughout the western US, we predicted that an exotic species, Tamarix, would have the greatest increase in suitable habitat relative to native counterparts under CC. We used an ecological niche model to predict range shifts of Populus fremontii, Salix gooddingii, Salix exigua and Tamarix, from present day to 2080s, under five general circulation models and one climate change scenario (A1B). Four major findings emerged. 1) Contrary to our original hypothesis, P. fremontii is projected to have the greatest increase in suitable habitat under CC, followed closely by Tamarix. 2) Of the native species, S. gooddingii and S. exigua showed the greatest loss in predicted suitable habitat due to CC. 3) Nearly 80 percent of future P. fremontii and Salix habitat is predicted to be affected by either CC or Tamarix by the 2080s. 4) By the 2080s, 20 percent of S. gooddingii habitat is projected to be affected by both Tamarix and CC concurrently, followed by S. exigua (19 percent) and P. fremontii (13 percent). In summary, while climate change alone will negatively impact both native willow species, Tamarix is likely to affect a larger portion of all three native species' distributions. We discuss these and other results in the context of prioritizing restoration and conservation efforts to optimize future productivity and biodiversity. As we are accounting for only direct effects of CC and Tamarix on native habitat, we present a possible hierarchy of effects- from the direct to the indirect- and discuss the potential for the indirect to outweigh the direct effects. Our results highlight the need to account for simultaneous challenges in the face of CC.
Incorporating if...then...personality signatures in person perception: beyond the person-situation dichotomy.

Three studies investigated conditions in which perceivers view dispositions and situations as interactive, rather than independent, causal forces when making judgments about another's personality. Study 1 showed that perceivers associated 5 common trait terms (e.g., friendly and shy) with characteristic if.then. (if situation a, then the person does x, but if situation b, then the person does y) personality signatures. Study 2 demonstrated that perceivers used information about a target's stable if.then. signature to infer the target's motives and traits; dispositional judgments were mediated by inferences about the target's motivations. Study 3 tested whether perceivers draw on if.then. signatures when making judgments about Big Five trait dimensions. Together, the findings indicate that perceivers take account of person-situation interactions (reflected in if.then. signatures) in everyday explanations of social behavior and personality dispositions. Boundary conditions are also discussed.
Current Trends in Wireless Mesh Sensor Networks: A Review of Competing Approaches

Finding a complete mesh-based solution for low-rate wireless personal area networks (LR-WPANs) is still an open issue. To cope with this concern, different competing approaches have emerged in the Wireless Mesh Sensor Networks (WMSNs) field in the last few years. They are usually supported by the IEEE 802.15. 4 standard, the most commonly adopted LR-WPAN recommendation for point-to-point topologies. In this work, we review the most relevant and up-to-date WMSN solutions that extend the IEEE 802.15. 4 standard to multi-hop mesh networks. To conduct this review, we start by identifying the most significant WMSN requirements (i.e., interoperability, robustness, scalability, mobility or energy-efficiency) that reveal the benefits and shortcomings of each proposal. Then, we re-examine thoroughly the group of proposals following different design guidelines which are usually considered by end-users and developers. Among all of the approaches reviewed, we highlight the IEEE 802.15. 5 standard, a recent recommendation that, in its LR-WPAN version, fully satisfies the greatest number of WMSN requirements. As a result, IEEE 802.15. 5 can be an appropriate solution for a wide-range of applications, unlike the majority of the remaining solutions reviewed, which are usually designed to solve particular problems, for instance in the home, building and industrial sectors. In this sense, a description of IEEE 802.15. 5 is also included, paying special attention to its efficient energy-saving mechanisms. Finally, possible improvements of this recommendation are pointed out in order to offer hints for future research.
Concept-based searching and browsing: a geoscience experiment

In the recent literature, we have seen the expansion of information retrieval techniques to include a variety of different collections of information. Collections can have certain characteristics that can lead to different results for the various classification techniques. In addition, the ways and reasons that users explore each collection can affect the success of the information retrieval technique. The focus of this research was to extend the application of our statistical and neural network techniques to the domain of geological science information retrieval. For this study, a test bed of 22,636 geoscience abstracts was obtained through the NSF/DARPA/NASA funded Alexandria Digital Library Initiative project at the University of California at Santa Barbara. This collection was analyzed using algorithms previously developed by our research group: concept space algorithm for searching and a Kohonen self-organizing map (SOM) algorithm for browsing. Included in this paper are discussions of our techniques, user evaluations and lessons learned.
Running head : VERB ASPECT AND COREFERENCE Verb Aspect , Event Structure , and Coreferential Processing

We used an offline story continuation task and an online ERP reading task to investigate coreference processing following sentences that portrayed transfer-of-possession events as either ongoing or completed using imperfective and perfective verb aspect (e.g., Amanda was shifting/shifted some poker chips to Scott.). The story continuation task demonstrated that people were more likely to begin continuations with references to the Goal than to the Source, but that perfective aspect strengthened this bias. In the ERP task we probed expectations for Source and Goal participants by employing pronouns that matched one of the participants in gender. The ERP results were consistent with the biases revealed in the story completion task and demonstrate that the difference in Goal bias for the two forms of aspect were manifested differently in the brain. These results provide novel behavioral and neurocognitive insight into how verb aspect influences the construction of situation models during language comprehension.
Complexity Results and Approximation Strategies for MAP Explanations

MAP is the problem of finding a most probable instantiation of a set of variables given evidence. MAP has always been perceived to be significantly harder than the related problems of computing the probability of a variable instantiation (Pr), or the problem of computing the most probable explanation (MPE). This paper investigates the complexity of MAP in Bayesian networks. Specifically, we show that MAP is complete for NPPP and provide further negative complexity results for algorithms based on variable elimination. We also show that MAP remains hard even when MPE and Pr become easy. For example, we show that MAP is NP-complete when the networks are restricted to polytrees, and even then can not be effectively approximated. Given the difficulty of computing MAP exactly, and the difficulty of approximating MAP while providing useful guarantees on the resulting approximation, we investigate best effort approximations. We introduce a generic MAP approximation framework. We provide two instantiations of the framework; one for networks which are amenable to exact inference (Pr), and one for networks for which even exact inference is too hard. This allows MAP approximation on networks that are too complex to even exactly solve the easier problems, Pr and MPE. Experimental results indicate that using these approximation algorithms provides much better solutions than standard techniques, and provide accurate MAP estimates in many cases.
Resistance to Varroa destructor (Mesostigmata: Varroidae) When Mite-Resistant Queen Honey Bees (Hymenoptera: Apidae) Were Free-Mated with Unselected Drones

Abstract This study demonstrated (1) that honey bees, Apis mellifera L, can express a high level of resistance to Varroa destructor Anderson & Trueman when bees were selected for only one resistant trait (suppression of mite reproduction); and (2) that a significant level of mite-resistance was retained when these queens were free-mated with unselected drones. The test compared the growth of mite populations in colonies of bees that each received one of the following queens: (1) resistant—queens selected for suppression of mite reproduction and artificially inseminated in Baton Rouge with drones from similarly selected stocks; (2) resistant × control—resistant queens, as above, produced and free-mated to unselected drones by one of four commercial queen producers; and (3) control—commercial queens chosen by the same four queen producers and free-mated as above. All colonies started the test with ≈0.9 kg of bees that were naturally infested with ≈650 mites. Colonies with resistant × control queens ended the 115-d test period with significantly fewer mites than did colonies with control queens. This suggests that beekeepers can derive immediate benefit from mite-resistant queens that have been free-mated to unselected drones. Moreover, the production and distribution of these free-mated queens from many commercial sources may be an effective way to insert beneficial genes into our commercial population of honey bees without losing the genetic diversity and the useful beekeeping characteristics of this population.
Child Support Models and the Perception of “ Fairness

Poverty. The views expressed here are those of the author alone. The author thanks the state and county child support staff from throughout the country who gave generously of their time and insights during the interview process. The author also thanks Carol Chellew and Rebekah Selekman for their contributions to this report as well as Dan Meyer for his thoughtful review.
Symmetric Interior Penalty DG Methods for the Compressible Navier-Stokes Equations II: Goal--Oriented A Posteriori Error Estimation

In this article we consider the application of the generalization of the symmetric version of the interior penalty discontinuous Galerkin finite element method to the numerical approximation of the compressible Navier--Stokes equations. In particular, we consider the a posteriori error analysis and adaptive mesh design for the underlying discretization method. Indeed, by employing a duality argument (weighted) Type I a posteriori bounds are derived for the estimation of the error measured in terms of general target functionals of the solution; these error estimates involve the product of the finite element residuals with local weighting terms involving the solution of a certain dual problem that must be numerically approximated. This general approach leads to the design of economical finite element meshes specifically tailored to the computation of the target functional of interest, as well as providing efficient error estimation. Numerical experiments demonstrating the performance of the proposed approach will be presented.
Tissue engineering of peripheral nerves: Epineurial grafts with application of cultured Schwann cells

After a simple nerve lesion, primary microsurgical suture is the treatment of choice. A nerve gap has to be bridged, with a nerve graft sacrificing a functioning nerve. Alternatively, tissue engineering of nerve grafts has become a subject of experimental research. It is evident that nerve regeneration requires not only an autologous, allogenous, or biodegradable scaffold, but additional interactions with regeneration‐promoting Schwann cells. In this study, we compared epineurial and acellularized epineurial tubes with and without application of cultured Schwann cells as alternative grafts in a rat sciatic nerve model. Autologous nerve grafts served as controls. Evaluation was performed after 6 weeks; afterwards, sections of the graft and distal nerve were harvested for histological and morphometrical analysis. Compared to controls, all groups showed a significantly lower number of axons, less well‐shaped remyelinizated axons, and a delay in clinical recovery (e.g., toe spread). The presented technique with application of Schwann cells into epineurial tubes did not offer any major advantages for nerve regeneration. Thus, in this applied model, neither the implantation of untreated nor the implantation of acellularized epineurial tubes with cultured Schwann cells to bridge nerve defects was capable of presenting a serious alternative to the present gold standard of conventional nerve grafts for bridging nerve defects in this model. © 2003 Wiley‐Liss, Inc. MICROSURGERY 23:72–77 2003
Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1

Abstract Insulin-like growth factor-binding protein (IGFBP)-1 is one of six structurally homologous proteins that specifically bind and modulate the mitogenic and metabolic actions of insulin-like growth factor (IGF)-I and IGF-II. Of the six IGFBP, IGFBP-1 is the only one that displays rapid dynamic regulation in vivo, with serum levels varying 10-fold or more in relation to meals. The complementary cDNA for IGFBP-1 was first reported in 1988. The predicted 234-amino acid sequence has a molecular mass of 25.3 kDa. The N-terminal and C-terminal regions are highly homologous among rat, human, and bovine sequences, and contain 18 conserved cysteines which are postulated to provide a framework for ligand binding. The 65-residue midregion is less homologous and does not contain cysteines, but does include a Pro-Glu-Ser-Thr (PEST) domain that is typical of rapidly metabolized proteins. The gene for IGFBP-1 has been localized to human chromosome region 7p12-p14, where it is contiguous with the gene for IGFBP-3. IGFBP-1 mRNA and protein expression have been identified in human liver and uterine decidua, and in nonhuman kidney. In vitro and in vivo studies indicate that insulin is the primary regulator of IGFBP-1 expression in these tissues, and that the primary effect of insulin is rapid inhibition of transcription. On the other hand, cortisol, glucagon, and cAMP stimulate IGFBP-1 production. Limited data also show a potent stimulatory effect of phorbol esters. A detailed review of IGFBP-1 levels and physiology in vivo and in vitro is presented. The function of IGFBP-1 is not completely defined. However, several studies demonstrate that IGFBP-1 inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. Furthermore, IGFBP-1 regulation by insulin and glucoregulatory hormones in vitro and limited in vivo data are consistent with a role for IGFBP-1 in glucose counterregulation.
Computation and Visualization of bifurcation Surfaces

The localization of critical parameter sets called bifurcations is often a central task of the analysis of a nonlinear dynamical system. Bifurcations of codimension 1 that can be directly observed in nature and experiments form surfaces in three-dimensional parameter spaces. In this paper, we propose an algorithm that combines adaptive triangulation with the theory of complex systems to compute and visualize such bifurcation surfaces in a very efficient way. The visualization can enhance the qualitative understanding of a system. Moreover, it can help to quickly locate more complex bifurcation situations corresponding to bifurcations of higher codimension at the intersections of bifurcation surfaces. Together with the approach of generalized models the proposed algorithm enables us to gain extensive insights in the local and global dynamics not only in one special system but in whole classes of systems. To illustrate this ability we analyze three examples from different fields of science.
Broad beam attenuation of kilovoltage photon beams: effect of ion chambers.

In kilovoltage X-ray treatment, beam shaping and shielding normal tissue are accomplished by thin sheets of lead cutout, the thickness of which is selected based upon either published data or measurements. Available broad beam attenuation (BBA) data are found to be unsatisfactory and are the subject of this investigation. BBA is defined as the ratio of intensity with (I) and without (I0) attenuating medium for a large field in a phantom. BBA = I(x,t,E)/I0(x,0,E), where x is the depth of measurement, t is the thickness of attenuator, and E is the beam energy. The depth x should be zero for kilovoltage beams and dmax for megavoltage beams. Unfortunately, x is limited by the window thickness which is the core of this study. A Farmer-type cylindrical ion chamber and three parallel plate ion chambers (Capintec, PS-033; Markus; and Holt) were used to measure BBA for kilovoltage beams from a Siemens Stabilipan unit. Results indicate that attenuation is strongly dependent on the window thickness. For the 240 kVp beam, the thickness of lead for 5% and 1% transmissions are 3.1 mm, and 5.2 mm, respectively, with the Capintec chamber. The corresponding values of lead thickness for the Markus chamber are 2.3 mm and 4.0 mm; for the Holt chamber the values are 1.1 mm and 2.2 mm; and for the cylindrical chambers the values are 1.1 mm and 2.3 mm, respectively. Similar variabilities in lead thickness with ion chambers were also noted for the other kilovoltage beams. The large differences in lead thicknesses produce enormous clinical errors, especially for shielding eye and other critical structures. For small thickness of lead (< 0.1 mm), a 20-fold increase in surface dose could be observed instead of usual beam attenuation. This is due to intense low energy photoelectrons liberated from lead sheets in the contact with tissue. It is concluded that the lead thickness required to shield normal tissue varies with ion chamber. Until national or international guidelines for broad beam transmission measurements are established, the shielding materials in contact with skin should be coated with a thin (> or = 0.3 mm) low atomic number medium. In such a situation, transmission measurements will be independent of the choice of an ion chamber.
Cenozoic mean greenhouse gases and temperature changes with reference to the Anthropocene

Cenozoic greenhouse gases (GHG) variations and warming periods underscore the extreme rates of current climate change, with major implications for the adaptability and survivability of terrestrial and marine habitats. Current rise rate of greenhouse gases, reaching 3.3 ppm CO2 per year during March 2015–2016, is the fastest recorded since the Paleocene‐Eocene Thermal Event (PETM) when carbon release to the atmosphere was about an order of magnitude less than at present. The ice core evidence of concentration of (GHG) and temperatures in the atmosphere/ocean/cryosphere system over the last 740 kyr suggests that the rate of rise in GHG over the last ~260 years, CO2 rates rising from 0.94 ppm yr−1 in 1959 (315.97 ppm) to 1.62 ppm yr−1 in 2000 (369.52 ppm) to 3.05 ppm yr−1 in 2015 (400.83 ppm), constitutes a unique spike in the history of the atmosphere. The reliance of pre‐740 kyr paleoclimate estimates on multiple proxies, including benthic and plankton fossils, fossil plants, residual organic matter, major and trace elements in fossils, sediments and soils, place limits on the resolution of pre‐upper Pleistocene paleoclimate estimates, rendering it likely recorded mean Cenozoic paleoclimate trends may conceal abrupt short‐term climate fluctuations. However, as exemplified by the Paleocene–Eocene thermal maximum (PETM) and earlier GHG and temperature spikes associated with major volcanic and asteroid impact events, the long‐term residence time of CO2 in the atmosphere extends the signatures of abrupt warming events to within detection limits of multiple paleoproxies. The mean post‐1750 temperature rise rate (approximately ~0.0034 °C per yr, or ~0.008 °C per yr where temperature is not masked by sulfur aerosols) exceeds those of the PETM (approximately ~0.0008–0.0015 °C per yr) by an order of magnitude and mean glacial termination warming rates (last glacial termination [LGT] ~ 0.00039; Eemian ~0.0004 °C per yr) by near to an order of magnitude. Consistent with previous interglacial peaks an increasing likelihood of collapse of the Atlantic Meridional Ocean Circulation is threatening a severe stadial event.