Miracle-dz/UniFAR-FTUs huggingface dataset:
Technologically Enriched and Boundaryless Lives

Computers and other communication technologies have irrevocably changed the nature of work, the workforce, and interpersonal relationships. This article suggests that these changes have resulted in a blurring of the distinction between life roles and an increase in feelings of meaningless and isolation. The authors argue that the dissolution of boundaries between life roles and the emotional sequelae of the digitization of our culture support a paradigm that reintegrates counseling and vocational psychology. Future counseling psychologists will be better equipped to provide services to clients whose lives are enriched and complicated by technology only if counseling psychology educators are able to provide them with the knowledge and skills to do so.
A new concept of strong controllability via the Schur complement in adaptive tracking

We propose a new concept of strong controllability associated with the Schur complement of a suitable limiting matrix. This concept allows us to extend the previous results associated with multidimensional ARX models. On the one hand, we carry out a sharp analysis of the almost sure convergence for both least squares and weighted least squares algorithms. On the other hand, we also provide a central limit theorem and a law of iterated logarithm for these two stochastic algorithms. Our asymptotic results are illustrated by numerical simulations.
Does Accreditation Matter? School Readiness Rates for Accredited Versus Nonaccredited Child Care Facilities in Florida’s Voluntary Pre-Kindergarten Program

Accreditation is a widely accepted indicator of quality in early education and includes many of the components cited in broad conceptualizations of quality. The purpose of this study was to examine whether kindergarten readiness rates differed between Florida child care facilities that were and were not accredited by any relevant national association or by the three Gold Seal Quality Care–approved associations as defined in Florida statute. To examine this, the authors looked at child care facilities licensed by the Florida Department of Children and Families and participating in the state Voluntary Pre-Kindergarten program in the years 2007 through 2010. Of the 4,322 facilities in this study, accreditation was not associated with better school readiness when children were tested in kindergarten in any years except 2007. The number of students who were deemed kindergarten ready was not different for accredited versus nonaccredited facilities in Florida. These results suggest that although accreditation may be a worthy goal for child care programs to pursue, it may be insufficient to affect child outcomes.
Does Ethical Leadership Influence Conflict among Employees? The Role of Resolution Efficacy

This study examined whether and how ethical leadership influences conflict among employees. Drawing on social learning theory, we predicted that ethical leadership will negatively influence three distinct types of conflict (i.e., relationship, task, and process conflict) through the mediation of resolution efficacy. Results from 165 employee–supervisor dyads in different organizations in Belgium showed support for our hypothesized model. These findings expand existing theory and previous research by providing new insight on the link between ethical leadership and conflict.
The Effect of Four Different Modes of Reading on Comprehension

THE PURPOSE of this study was to determine which of four modes of reading (oral reading to an audience, oral reading to oneself, silent reading, silent reading while listening) best facilitates the answering of post comprehension questions. The comprehension questions included gist, literal recall of details, inferences, and scriptal comparisons. Forty-eight subjects read an expository passage in each of the modes and answered the questions. The results supported equivalent comprehension following silent and oral reading to oneself. Both of these modes were superior to oral reading to an audience. In addition, silent reading was found to facilitate comprehension to a greater extent than did silent reading while listening to the text being read.
The influence of caprate on rectal absorption of phenoxymethylpenicillin: experience from an in‐vivo perfusion in humans

The aim of this in‐vivo perfusion study in humans was to investigate the influence of a penetration enhancer, sodium caprate, on the rectal absorption of phenoxymethylpenicillin and antipyrine. Six subjects, 3 male and 3 female, were included in two separate studies using perfusion solution of different pH (T1 and T2, respectively). Each in‐vivo rectal perfusion investigation lasted for 200 min and consisted of two periods of 100 min, the first serving as a control, and sodium caprate being added in the second period in both T1 and T2. The concentrations of phenoxymethylpenicillin, antipyrine and sodium caprate in the outlet perfusate were assayed by HPLC, as was the plasma concentrations of phenoxymethylpenicillin. At pH 6.0 (0–100 min) the fraction absorbed (fabs) and effective permeability (Peff) of phenoxymethylpenicillin were 0.3% and 0.06 × 10−4cms−1, respectively, and remained unaffected by the addition of sodium caprate. When the same subjects were perfused at pH 7.4, the fabs and Peff of phenoxymethylpenicillin were 2.4% and 0.11 times 10−4cms−1 (0–100 min), respectively, also remaining unchanged by addition of sodium caprate (100–200 min). It was possible to determine the plasma AUC of phenoxymethylpenicillin after addition of sodium caprate in three subjects at both pHs; this was in the range of 14.0–62.8 and 56.4–231 (min μ mol L−1) at pH 6.0 and 7.4, respectively. Interestingly, there was a correlation between Peff for sodium caprate and the individual plasma AUC and Cmax of phenoxymethylpenicillin, which indicates that the permeability of the enhancer in the tissue upon which it should act is crucial for achieving an effect. The fabs and the Peff of antipyrine were not affected at either pH when sodium caprate was added to the perfusion solution. In conclusion, the plasma pharmacokinetics of phenoxymethylpenicillin suggested a slightly increased rectal absorption at pH 7.4 in subjects where sodium caprate was transported into the rectal tissue. However, the increased Peff for phenoxymethylpenicillin was too small to detect from the outlet perfusate, which suggests that sodium caprate alone has a limited effect on the permeability in‐vivo across the rectal epithelium when it is presented in a solution.
Molecular Monitoring of Succession of Bacterial Communities in Human Neonates

ABSTRACT The establishment of bacterial communities in two healthy babies was examined for more than the first 10 months of life by monitoring 16S ribosomal DNA (rDNA) diversity in fecal samples by PCR and denaturing gradient gel electrophoresis (DGGE) and by analyzing the sequences of the major ribotypes. DGGE profiles of the dominant populations in the intestines of the infants were obtained by analyzing daily or weekly fecal samples. After delivery, the germfree infant gastrointestinal tracts were rapidly colonized, and the succession of bacteria in each ecosystem was monitored. During the first few days of life the profiles were simple, but they became more complex as the bacterial diversity increased with time in both babies. Clone libraries of amplified 16S rDNA fragments from baby feces were constructed, and these libraries allowed identification of the bacterial types by comparative DNA sequence analysis; the bacteria identified included members of the genera Bifidobacterium, Ruminococcus, Enterococcus, Clostridium, and Enterobacter. Species most closely related to the genera Bifidobacterium and Ruminococcus in particular dominated the intestinal microbiota based on the stability over time and the numbers, as estimated by the intensities of the bands. However, 19 of the 34 cloned rDNA sequences exhibited less than 97% identity with sequences of known bacteria or cloned sequences in databases. This study showed that using PCR-DGGE and 16S rDNA sequence analysis together resulted in a dynamic description of bacterial colonization in the infant intestinal ecosystem and allowed visualization of bacteria that are difficult to cultivate or to detect by other methods.
The demographic transition revisited as a global process

With dramatic declines in fertility taking place throughout the world, it is increasingly important to understand the demographic transition as a global process. While this universality was a cornerstone of classic transition theories, for many decades it was largely neglected by experts because fertility in the developing world did not seem to follow the expected pattern. When comparing earlier and more recent transition experiences, important similarities and disparities can be seen. Everywhere mortality decline appears to have played a central role for fertility decline. The differences in the timing of the response of fertility to mortality decline, with very small gaps historically and prolonged ones in more recent transitions, plus the much more rapid decline in vital rates in many developing countries, constitute an important challenge to any general explanation of the process. The specific characteristics of recent transitions have led to decades of higher population growth rates, and promise to give way to much more rapid dynamics of population ageing in many countries. This may limit the ability of newcomers to take full advantage of the demographic transition for the social and economic modernisation of their societies. Copyright © 2004 John Wiley & Sons, Ltd.
The relative frequency of the synthetic and composite futures in the newspaper Ouest-France and some observations on distribution

Figures on the relative frequency of synthetic and composite future forms in Ouest-France are presented and compared with those of earlier studies on the passé simple and passé composé. The synthetic future is found to be dominant. Possible formal explanations for distribution are found to be inconclusive. Distribution across different text-types is found to be more promising, since contrastive functions of the two forms can be identified in texts where they co-occur. The composite future typically reports new proposals or plans as current news, while the synthetic future outlines details that will be realised at the time of implementation. Both functions are important in dailies, but current news is more often expressed in the present tense at the expense of the composite future.
Evaluation of Quality of Life of Adult Cancer Patients Attending Tikur Anbessa Specialized Referral Hospital, Addis Ababa Ethiopia

Background Little is known about the quality of life of cancer patients in the Ethiopian context. This study evaluated quality of life of cancer patients in Ethiopia. Methods A cross-sectional study was conducted in Addis Ababa University Tikur Anbessa Specialized Referral Hospital Addis Ababa, Ethiopia (TASRH) from March to May 2013. A total of 388 cancer patients were included. Translated in to Amharic, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QOL C-30) was used to measure Quality of life (QoL). The data was analyzed with SPSS Version 17.0. Results Among the participants, 251(64.7%) were men and 138(35.6%) were below the age of 40 years. Large proportion of patients were diagnosed with breast cancer, 114(29.4%), and cervical cancer, 102(26.3%), and the clinical stages during the beginning of therapy were at stage II a 133(34.3%). The mean of global health status/QoL was 57.28 (SD= 25.28). Quality of life was found to be associated with some functional scales as role functioning, P≤0.001, social function, P=0.00, and symptom scales as pain, P=0.00, loss of appetite, P=0.004, and financial impact, P=0.02, but no associations were noted in relation to socio demographic characteristics. Conclusions Quality of life assessments should be included in patient treatment protocols to improve their quality of life since being a cancer patient may be associated with a high level of impairment in different aspects of life.
Functional Consequences of Bipolar Affective Disorder: An Occupational Therapy Perspective

An investigation into the functional consequences for an outpatient group of euthymic clients with the diagnosis of bipolar disorder(N=62) was conducted at the Bipolar Clinic at the Clarke Institute of Psychiatry. Participants completed a questionnaire that was based on the Role Checklist and that measured their level of involvement, satisfaction, and functioning in various life roles. The questionnaire also included criteria for adaptive level of functioning. Approximately one third of the sample did not meet the criteria for adaptive level of functioning. Furthermore the self-care, productivity and leisure problems identified in the open-ended questions suggest that the functional consequences of bipolar affective disorder are substantial for this euthymic outpatient group of clients. The implications of these results are discussed in the context of the Occupational Therapy Guidelines for Client-Centred Mental Health Practice.
Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway

Non-alcoholic fatty liver disease is one of the most important causes of liver-related morbidity in children. In non-alcoholic fatty liver disease, the activation of liver resident macrophage pool is a central event in the progression of liver injury. The aims of the present study were to evaluate the polarization of liver macrophages and the possible role of Wnt3a production by macrophages in hepatic progenitor cell response in the progression of pediatric non-alcoholic fatty liver disease. 32 children with biopsy-proven non-alcoholic fatty liver disease were included. 20 out of 32 patients were treated with docosahexaenoic acid for 18 months and biopsies at the baseline and after 18 months were included. Hepatic progenitor cell activation, macrophage subsets and Wnt/β-catenin pathway were evaluated by immunohistochemistry and immunofluorescence. Our results indicated that in pediatric non-alcoholic fatty liver disease, pro-inflammatory macrophages were the predominant subset. Macrophage polarization was correlated with Non-alcoholic fatty liver disease Activity Score, ductular reaction, and portal fibrosis; docosahexaenoic acid treatment determined a macrophage polarization towards an anti-inflammatory phenotype in correlation with the reduction of serum inflammatory cytokines, with increased macrophage apoptosis, and with the up-regulation of macrophage Wnt3a expression; macrophage Wnt3a expression was correlated with β-catenin phosphorylation in hepatic progenitor cells and signs of commitment towards hepatocyte fate. In conclusion, macrophage polarization seems to have a key role in the progression of pediatric non-alcoholic fatty liver disease; the modulation of macrophage polarization could drive hepatic progenitor cell response by Wnt3a production.
An optomechanical elevator: Transport of a Bloch oscillating Bose-Einstein condensate up and down an optical lattice by cavity sideband amplification and cooling

We analyze the optomechanics of an atomic Bose-Einstein condensate interacting with the optical lattice inside a laser-pumped optical cavity and subject to a uniform bias force such as gravity. An atomic wave packet in a tilted lattice undergoes Bloch oscillations; in a cavity the backaction of the atoms on the light leads to a time-dependent modulation of the intracavity lattice at the Bloch frequency. When the Bloch frequency is on the order of the cavity damping rate we find transport of the atoms either up or down the lattice. The transport dynamics can be interpreted as a manifestation of dynamical backaction-induced sideband damping/amplification of the optomechanical Bloch oscillator. Depending on the sign of the pump-cavity detuning, atoms are transported either with or against the bias force accompanied by an up- or down-conversion of the frequency of the pump laser light. We also evaluate the prospects for using the optomechanical Bloch oscillator to make continuous measurements of forces by reading out the Bloch frequency. In this context we establish the significant result that the optical spring effect is absent and the Bloch frequency is not modified by the backaction.
Lipid Composition of Multilamellar Bodies Secreted by Dictyostelium discoideum Reveals Their Amoebal Origin

ABSTRACT When they are fed with bacteria, Dictyostelium discoideum amoebae produce and secrete multilamellar bodies (MLBs), which are composed of membranous material. It has been proposed that MLBs are a waste disposal system that allows D. discoideum to eliminate undigested bacterial remains. However, the real function of MLBs remains unknown. Determination of the biochemical composition of MLBs, especially lipids, represents a way to gain information about the role of these structures. To allow these analyses, a protocol involving various centrifugation procedures has been developed to purify secreted MLBs from amoeba-bacterium cocultures. The purity of the MLB preparation was confirmed by transmission electron microscopy and by immunofluorescence using H36, an antibody that binds to MLBs. The lipid and fatty acid compositions of pure MLBs were then analyzed by high-performance thin-layer chromatography (HPTLC) and gas chromatography (GC), respectively, and compared to those of amoebae as well as bacteria used as a food source. While the bacteria were devoid of phosphatidylcholine (PC) and phosphatidylinositol (PI), these two polar lipid species were major classes of lipids in MLBs and amoebae. Similarly, the fatty acid composition of MLBs and amoebae was characterized by the presence of polyunsaturated fatty acids, while cyclic fatty acids were found only in bacteria. These results strongly suggest that the lipids constituting the MLBs originate from the amoebal metabolism rather than from undigested bacterial membranes. This opens the possibility that MLBs, instead of being a waste disposal system, have unsuspected roles in D. discoideum physiology.
Short-Term Mood Repair Through Art: Effects of Medium and Strategy

Abstract This study examined the effects of expressive media (drawing versus writing) and emotion regulation strategy (coping by venting versus coping by distraction) on short-term mood repair. After inducing a sad mood in 40 participants, the researchers randomly assigned them to one of two conditions: drawing or writing. Mood valence was assessed before and after the activity, and participants reported whether they used the activity to vent or to distract themselves. Findings indicated that mood valence was significantly more positive after drawing than writing, and more positive when individuals reported using distraction rather than venting to regulate their emotions. Drawing in this study was a more effective means of immediate mood repair than writing; both activities repaired mood more effectively through distraction than through venting.
The autocue? self-generated phonemic cues in the treatment of a disorder of reading and naming

Abstract This study describes a therapy programme that aimed to improve oral reading and spoken naming in a deep dyslexic patient by teaching the patient grapheme-phoneme correspondences. This aim was achieved and the improvement could be attributed to the specific effects of the therapy. However, the pattern of results obtained was very different to that predicted. The patient proved unable to perform or to relearn one of the processes necessary for successful reading by a sublexical routine (blending of individual phonemes to form a word). It is concluded that the improvement had been achieved not by a learned mechanism for sublexical reading but instead by enabling the use of patient-generated phonemic cues. The therapy had enabled the patient to produce successfully the phoneme associated with the initial letter of the word, which then acted as a phonemic cue facilitating reading of that word. Spoken naming was also facilitated as information on the written form of the word could similarly be used to .
Design and Experiment of a New Maglev Design Using Zero-Field-Cooled YBCO Superconductors

The existing high-temperature superconducting magnetic levitation (Maglev) vehicles are based on field-cooled (FC) superconductors mainly to guarantee vehicle lateral stability. Usually, this solution presents two drawbacks: levitation and guidance forces depend on how the FC process has been featured, and flux-flow phenomenon, which induces significant power losses in superconductors during the vehicle's displacement, can put them out of superconductivity state. To minimize these problems, a zero-field-cooled (ZFC) Maglev vehicle was designed and successfully developed in our laboratory. Measurements of its levitation and guidance forces and also its vertical and damping properties were carried out. These results, when compared with those ones from an FC vehicle, show that the ZFC vehicle has higher levitation forces and similar guidance force values. However, guidance forces do not depend on cooling height value as what happens in an FC vehicle, despite that the ZFC vehicle also presents some power losses. The experimental results indicated that power losses from vertical and lateral vehicle oscillations are lower in a ZFC one. However, this effect will have to be compensated by using some technique to reduce ZFC vehicle oscillations in the future.
Desmoplastic Small Round Cell Tumor: Current Management and Recent Findings

Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive mesenchymal tumor that develops in the abdominal cavity of young men adults. Patients typically present with symptoms of abdominal sarcomatosis. Diagnosis is based on histological analysis of biopsies which typically show small round blue cells in nests separated by an abundant desmoplastic stroma. DSRCT is associated with a unique chromosomal translocation t(11:22) (p 13; q 12) that involves the EWSR1 and WT1 genes. The prognosis is particularly poor; median survival ranges from 17 to 25 months, largely due to the presentation of the majority of patients with metastatic disease. Management of DSRCT remains challenging and current schemes lack a significant cure rate despite the use of aggressive treatments such as polychemotherapy, debulking surgery and whole abdominal radiation. Several methods are being evaluated to improve survival: addition of chemotherapy and targeted therapies to standard neoadjuvant protocol, completion of surgical resection with HIPEC, postoperative IMRT, treatment of hepatic metastases with [90Y]Yttrium microsphere liver embolization.