Miracle-dz/UniFAR-FTUs huggingface dataset:
Dyeing characteristics and functionability of tussah silk fabric with oak bark extract

In order to realize the ultraviolet (UV) protection property and antimicrobial activity simultaneously, as well as the natural dyeing process, oak bark extract was prepared and applied to dye tussah silk fabric. The effects of dyeing pH value, temperature, time and mordant kinds on dyeing properties of tussah silk fabric were analyzed. The results indicated that the optimum direct dyeing conditions were as follows: pH 5.0, temperature 98℃, time 80 min. As for the mordant dyeing process, the K/S values of the post-mordant dyed samples were higher than those of the pre-mordant dyed samples. The color of the direct, aluminum potassium sulfate, copper sulfate and the ferrous sulfate dyed samples were brown, yellow-brown, dark brown and gray black, respectively. The washing, rubbing and light fastness of the three mordants dyed samples were all good. Moreover, the dyed samples showed an excellent UV protection property and antimicrobial activity. The UV protection factor values of the mordant dyed sample were more than 40; the reduction in bacterial count percent against S. aureus and E. coli reached up to and above 85% and 80%, respectively; and the weight gain rate was more than 6%. Furthermore, the dyed samples had good washing durability of the UV protection function and antimicrobial activity even after 50 consecutive launderings.
Human 8-oxoguanine DNA glycosylase gene polymorphism (Ser326Cys) and cancer risk: updated meta-analysis

Genetic polymorphism of human 8-oxoguanine glycosylase 1 (hOGG1) has been reported to have a relationship with the risk of the development of various cancers. Many studies have described the influence of Ser326Cys polymorphism of the hOGG1 gene on cancer susceptibility. However, the results have remained inconclusive and controversial. Therefore, we performed a meta-analysis to more precisely determine the relationship between the hOGG1 polymorphism and the development of cancer. Electronic databases including PubMed, Embase, Google Scholar, and the Korean Studies Information Service System (KISS) were searched. The odds ratio (OR), 95% confidence interval (CI), and p value were calculated to assess the strength of the association with the risk of cancer using Comprehensive Meta-analysis software (Corporation, NJ, USA). The 127 studies including 38,757 cancer patients and 50,177 control subjects were analyzed for the meta-analysis. Our meta-analysis revealed that G allele of Ser326Cys polymorphism of the hOGG1 gene statistically increased the susceptibility of cancer (all population, OR = 1.092, 95% CI = 1.051-1.134, p < 0.001; in Asian, OR = 1.095, 95% CI = 1.048-1.145, p < 0.001; in Caucasian, OR = 1.097, 95% CI = 1.033-1.179, p = 0.002). Also, other genotype models showed significant association with cancer (p < 0.05, respectively). The present meta-analysis concluded that the G allele was associated with an increased risk of cancer. It suggested that the hOGG1 polymorphism may be a candidate marker of cancer.
Predicting the bioavailability of sediment‐bound uranium to the freshwater midge (Chironomus dilutus) using physicochemical properties

Assessment of uranium (U)‐contaminated sediment is often hindered by the inability to accurately account for the physicochemical properties of sediment that modify U bioavailability. The present goal was to determine whether sediment‐associated U bioavailability could be predicted over a wide range of conditions and sediment properties using simple regressions and a geochemical speciation model, the Windermere Humic Aqueous Model (WHAM7). Data from a U‐contaminated field sediment bioaccumulation test, along with previously published bioaccumulation studies with U‐spiked field and formulated sediments, were used to examine the models. Observed U concentrations in Chironomus dilutus larvae exposed to U‐spiked and U‐contaminated sediments correlated well (r2 > 0.74, p < 0.001) with the WHAM‐calculated concentration of U bound to humic acid, indicating that humic acid may be a suitable surrogate for U binding sites (biotic ligands) in C. dilutus larvae. Subsequently, the concentration of U in C. dilutus was predicted with WHAM7 by numerically optimizing the equivalent mass of humic acid per gram of organism. The predicted concentrations of U in C. dilutus larvae exposed to U‐spiked and U‐contaminated field sediment compared well with the observed values, where one of the regression models provided a slightly better fit (mean absolute error = 18.1 mg U/kg dry wt) than WHAM7 (mean absolute error = 34.2 mg U/kg dry wt). The regression model provides a predictive capacity with a minimal number of variables, whereas WHAM7 provides additional complementary insight into the chemical variables influencing the speciation, sorption, and bioavailability of U in sediment. The present results indicate that physicochemical properties of sediment can be used to account for variability in U bioavailability as measured through bioaccumulation in chironomids exposed to U‐contaminated sediments. Environ Toxicol Chem 2018;37:1146–1157. © 2017 SETAC
Bond strength and failure characteristics of zirconia-based dental ceramic to resin cements.

Bond strength and failure characteristics of zirconia-based dental ceramic to resin cements Premwara Triwatana, Porntida Visuttiwattanakorn, Kallaya Suputtamongkol, Nutthakrij Butrangamdee Premwara Triwatana, Porntida Visuttiwattanakorn, Kallaya Suputtamongkol, Nutthakrij Butrangamdee Prosthodontic Department, Faculty of Dentistry, Mahidol University Bond strength and failure characteristics of zirconia-based dental ceramic to resin cements
Biochemical and Molecular Roles of Nutrients Mechanisms of Decreased Lipoprotein Lipase Activity in Adipocytes of Starved Rats Depend on Duration of Starvation

The aim of this study was to delineate the mechanisms by which varying periods of starvation decrease lipoprotein lipase (LPL) activity in rat adipose tissue. LPL mRNA levels and rates of LPL synthesis, degradation and secretion were compared in adipocytes from male rats that had been fed or starved for 1 or 3 d. The decreased LPL activity after 3 d of starvation (076%) was explained mainly by a 50% decrease in the relative abundance of LPL mRNA levels (Põ 0.05) and a parallel 50% decrease in relative rates of LPL biosynthesis (P õ 0.05). In contrast, starvation for 1 d decreased total LPL activity by 47% (P õ 0.05) but did not affect LPL mRNA levels or relative rates of LPL biosynthesis. Pulse-chase studies demonstrated that 1 d of starvation increased the rate of degradation of newly synthesized LPL (P õ 0.05) and markedly decreased its secretion into the medium (P õ 0.05). A decrease in overall protein synthesis also contributed to the decreased LPL activity after 1 and 3 d of starvation. We conclude that the relative importance of preand post-translational mechanisms in regulating adipose tissue LPL activity depends on the duration of starvation. During short-term starvation, degradation of newly synthesized LPL is an important determinant to its secretion from the adipocyte and hence its functional activity at the capillary endothelium. J. Nutr. 128: 940–946, 1998.
PCSK9 Is Increased in Youth With Type 1 Diabetes

Type 1 diabetes (T1D) is associated with a 10-fold increase in cardiovascular disease (CVD) risk, due in part to dyslipidemia. Patients with poorly controlled T1D show an increase in total and LDL cholesterol as well as elevated apolipoprotein B (ApoB) levels. Moreover, even patients with well-controlled T1D can show increased levels of ApoB. Dyslipidemia is particularly important in females with T1D, as the atheroprotective lipoprotein profile and reduced risk of CVD usually observed in females without diabetes are lost in females with diabetes (1,2). Proprotein convertase subtilisin/kexin type 9 (PCSK9) has recently emerged as a novel regulator of plasma cholesterol levels: gain-of-function PCSK9 mutations increase LDL cholesterol and CVD risk, whereas inhibitors of PCSK9 lower LDL cholesterol. Although PCSK9 is increased in individuals with obesity and type 2 diabetes (3,4), it is not known whether PCSK9 levels are also changed in individuals with T1D. Here, we measured PCSK9 levels in a subset of a previously described cohort of T1D and control subjects (5). For the current study, subjects with serum available for PCSK9 measurement were matched for age and sex between each group using the frequency matching method. Subjects who reported taking statin medications at the time of the study were excluded from the analyses ( n = 3, all from T1D …
Synthesis of the Novel Type of Bimodal Ceramic Nanowires from Polymer and Composite Fibrous Mats

The purpose of this paper was to produce SiO2 and TiO2 nanowires via the electrospinning process from a polyvinylpyrrolidone (PVP)/Tetraethyl orthosilicate (TEOS)/Titanium (IV) butoxide (TNBT)/dimethylformamide (DMF) and ethanol (EtOH) solution. The as-obtained nanofibers were calcined at temperatures ranging from 400 °C to 600 °C in order to remove the organic phase. The one-dimensional ceramic nanostructures were studied using a scanning electron microscope (SEM) and a transmission electron microscope (TEM) to analyze the influence of the used temperature on the morphology and structures of the obtained ceramic nanomaterials. In order to examine the chemical structure of the nanowires, energy dispersive spectrometry (EDX) and Fourier-Transform Infrared spectroscopy (FTIR) were used. The optical property analysis was performed on the basis of UV-Vis spectra of absorbance as a function of the wavelength. Using the modified Swanepoel method, which the authors proposed and the recorded absorbance spectra allowed to determine the banded refractive index n, real n′ and imaginary k part of the refractive index as a function of the wavelength, complex dielectric permeability ε, and real and imaginary part εr and εi of the dielectric permeability as a function of the radiation energy of the produced ceramic nanowires.
Socioeconomic status, labour market connection, and self-rated psychological health: The role of social capital and economic stress

Aims: To investigate the association between socioeconomic status, unemployment and self-rated psychological health, taking economic stress and horizontal trust into account. Design/setting/participants/measurements: The 2008 public health survey in Skåne is a cross-sectional postal questionnaire study with a 55% participation rate. A random sample was invited and 28,198 persons aged 18–80 participated. Logistic regression models were used to investigate associations between socioeconomic status by occupation (SES), labour market connection and self-rated psychological health (GHQ12). The multiple regression analyses included age, country of birth, education, economic stress and generalized (horizontal) trust. Results: 13.8% of the men and 18.2% of the women had poor psychological health. Poor psychological health was more common among the young, among those born abroad, among those with lower education, with economic stress, and low horizontal trust. There were no significant differences between the employed and self-employed groups. However, the people who had retired early, the unemployed and those on long-term sick leave had significantly higher odds ratios of poor psychological health than higher non-manual employees throughout the analyses. Conclusions: There were no differences in psychological health between non-manual employees in higher positions and other employed and self-employed SES groups among men or women. In contrast, the early retired, the unemployed and the category on long-term sick leave had significantly higher odds ratios of poor psychological health among both men and women throughout the multiple analyses. Both economic stress and trust affected this association (i.e., lowered the odds ratios of poor psychological health), but affected by economic stress to a somewhat higher extent.
Familial Risk for Insomnia Is Associated With Abnormal Cortisol Response to Stress

Objectives Abnormalities in the stress system have been implicated in insomnia. However, studies examining physiological stress regulation in insomnia have not consistently detected differences in the hypothalamic-pituitary-adrenal (HPA)-axis response to stress. One explanation may be that deficits in the stress system are associated specifically with a biological vulnerability to insomnia rather than the phenotypic expression of insomnia. To examine stress response as a function of vulnerability to insomnia, this study tested response to the Trier Social Stress Test in a sample of healthy sleepers with varying familial risks for insomnia. Methods Thirty-five healthy individuals with and without familial risk for insomnia were recruited to complete a laboratory stressor. Participants with one or both biological parents with insomnia were categorized as positive for familial risk, whereas those without biological parents with insomnia were categorized as negative for familial risk. Participants completed the Trier Social Stress Test in the laboratory, and psychological and physiological (autonomic and HPA-axis) responses were compared. Results Despite self-reported increases in anxiety, those positive for familial risk exhibited a blunted cortisol response relative to those without familial risk for insomnia. Individuals with blunted cortisol also reported heightened reactivity to personal life stressors, including increased sleep disturbances, elevated cognitive intrusions, and more behavioral avoidance. Conclusions Findings from this study provide initial evidence that abnormal stress regulation may be a biological predisposing factor conferred via familial risk for insomnia. This deficit may also predict negative consequences over time, including insomnia and the associated psychiatric comorbidities.
Aging and HIV-Related Caregiving in Sub-Saharan Africa: A Social Ecological Approach.

BACKGROUND AND OBJECTIVES We reviewed the literature on older adults (OAs) who are caring for persons living with HIV/AIDS in sub-Saharan Africa (SSA), with the goal of adapting models of caregiver stress and coping to include culturally relevant and contextually appropriate factors specific to SSA, drawing on both life course and cultural capital theories. RESEARCH DESIGN AND METHODS A systematic literature search found 81 articles published between 1975 and 2016 which were reviewed using a narrative approach. Primary sources of articles included electronic databases and relevant WHO websites. RESULTS The main challenge of caregiving in SSA reflects significant financial constraints, specifically the lack of necessities such as food security, clean water, and access to health care. Caregiving is further complicated in SSA by serial bouts of caring for multiple individuals, including adult children and grandchildren, in the context of high levels of stigma associated with HIV. Factors promoting caregiver resilience included spirituality, bidirectional (reciprocal) caregiving, and collective coping strategies. DISCUSSION AND IMPLICATIONS The creation of a theoretical model of caregiving which focuses more broadly on the sociocultural context of caregiving could lead to new ways of developing interventions in low-resources communities.
Alcohol Consumption and Longitudinal Trajectories of Physical Functioning in Central and Eastern Europe: A 10-Year Follow-up of HAPIEE Study

Background: Physical functioning (PF) is an essential domain of older persons’ health and quality of life. Health behaviors are the main modifiable determinants of PF. Cross-sectionally, alcohol consumption appears to be linked to better PF, but longitudinal evidence is mixed and very little is known about alcohol consumption and longitudinal PF trajectories. Methods: We conducted longitudinal analyses of 28,783 men and women aged 45–69 years from Novosibirsk (Russia), Krakow (Poland), and seven towns of the Czech Republic. At baseline, alcohol consumption was measured by a graduated frequency questionnaire and problem drinking was evaluated using the CAGE questionnaire. PF was assessed using the Physical Functioning Subscale of the SF-36 instrument at baseline and three subsequent occasions. Growth curve modeling was used to estimate the associations between alcohol consumption and PF trajectories over 10-year follow-up. Results: PF scores declined during follow-up in all three cohorts. Faster decline in PF over time was found in Russian female frequent drinkers, Polish female moderate drinkers, and Polish male regular heavy drinkers, in comparison with regular and/or light-to-moderate drinkers. Nondrinking was associated with a faster decline compared with light drinking only in Russian men. Problem drinking and past drinking were not related to the decline rate of PF. Conclusions: This large longitudinal study in Central and Eastern European populations with relatively high alcohol intake does not strongly support the existence of a protective effect of alcohol on PF trajectories; if anything, it suggests that alcohol consumption is associated with greater deterioration in PF over time.
Genetic Basis of Drug-Induced Liver Injury: Present and Future

Abstract There is considerable evidence that susceptibility to idiosyncratic drug-induced liver injury (DILI) is genetically determined. Though genetic associations with DILI have been reported since the 1980s, the development of genome-wide association studies has enabled genetic risk factors for DILI, in common with other diseases, to be detected and confirmed more confidently. Human leukocyte antigen (HLA) genotype has been demonstrated to be a strong risk factor for development of DILI with a range of drugs and the underlying mechanism, probably involving presentation of a drug-peptide complex to T cells is increasingly well understood. However, specific HLA alleles are not associated with all forms of DILI and non-HLA genetic risk factors, especially those relating to drug disposition, also appear to contribute. For some drugs, there is evidence of a dual role for HLA and drug metabolism genes. Though the associations with non-HLA genes have been less well replicated than the HLA associations, there is increasing evidence that drug metabolism genes such as NAT2 and UGT2B7 contribute to some forms of DILI. Translating current genetic findings on DILI susceptibility to the clinic has been relatively slow, but some progress is now being made. In the future, DNA sequencing may lead to the identification of rare variants that contribute to DILI. Developments in the related area of epigenomics and in the development of improved models for DILI by use of genetically defined induced pluripotent stem cells should improve understanding of the biology of DILI and inform drug development.
Does sympathoadrenal activity predict changes in body fat? An 18-y follow-up study.

BACKGROUND Whether alterations in the sympathoadrenal system contribute to obesity or, rather, are consequences of it, is an unresolved issue. OBJECTIVE We hypothesized that the sympathoadrenal system plays a predictive role in the development of body fat. DESIGN At entry, arterial plasma epinephrine and norepinephrine concentrations were measured in 99 healthy men (x +/- SD age: 19.3 +/- 0.4 y) at rest and during a mental stress test and a cold pressor test. Body mass index (BMI; in kg/m(2)), waist circumference, and triceps skinfold thickness were measured at entry and after 18 y of follow-up. RESULTS Eighty subjects (81%) were available for follow-up analyses after a mean (+/-SD) of 18.0 +/- 0.9 y. The epinephrine responses to the mental stress test (E(MST)) showed a negative relation to changes in BMI (P = 0.01) and waist circumference (P = 0.007). The mean increase in BMI was 6.3 among subjects in the lowest E(MST) quartile and 3.7 in the remaining subjects. In multiple regression analyses corrected for level of exercise, BMI, waist circumference, and triceps skinfold thickness at entry, E(MST) was found to be a consistent negative predictor of future BMI (P = 0.005), waist circumference (P = 0.001), and triceps skinfold thickness (P = 0.05). CONCLUSIONS We present the first long-term follow-up study in whites showing that the epinephrine response to mental stress is a negative predictor of future BMI, waist circumference, and triceps skinfold thickness after 18 y of follow-up. These findings may provide further insights into the pathophysiology of obesity.
Substrate oxidation and control of food intake in men after a fat-substitute meal compared with meals supplemented with an isoenergetic load of carbohydrate, long-chain triacylglycerols, or medium-chain triacylglycerols.

BACKGROUND It has been suggested that hunger may be delayed and food intake reduced under metabolic conditions that spare carbohydrate oxidation. OBJECTIVE Our objective was to examine the role of glucose metabolism in the control of food intake in men by using medium-chain triacylglycerols (MCTs) to spare carbohydrate oxidation. DESIGN In 10 male volunteers, isolated and deprived of any time cues, we studied the effects of 4 lunches on hunger ratings, the duration of satiety, the amount of food ingested at dinner, energy expenditure, substrate oxidation, and plasma variables until the time of the dinner request. One lunch was a basic 2310-kJ meal containing 40 kJ fat substitute (Sub lunch). The 3 other lunches consisted of the same basic meal supplemented with either 1200 kJ long-chain triacylglycerols (LCT lunch), 1200 kJ MCTs (MCT lunch), or 900 kJ carbohydrate plus 300 kJ LCTs (Cho lunch). RESULTS Energy expenditure was not significantly different after the different lunches, but carbohydrate oxidation was lower after the MCT and LCT lunches than after the Cho lunch. Fat oxidation was greater after the MCT and LCT lunches. The time of the dinner request was significantly delayed after the Cho lunch. Food intake at dinner was significantly lower after the MCT lunch than after the Sub and Cho lunches, but the dinner meal request was not delayed. CONCLUSION Carbohydrate may have a greater role in the duration of satiety than does fat, but MCTs may play an active role in other aspects of the control of food intake, especially in satiation at the next meal.
The thermal decomposition and heat release properties of the nylon/cotton, polyester/cotton and Nomex/cotton blend fabrics

Cotton blends are very important and widely used in our lives. In this research, the heat release properties and the flammability of the nylon/cotton, the polyester/cotton and the Nomex/cotton blends are investigated. By comparing with the heat release rate (HRR) and other thermal parameters calculated from their individual components, it is found that both the nylon and the polyester have interaction when they are blended with cotton during the decomposition process. For the nylon/cotton fabrics, the blend has lower total heat release (THR) and much higher percent char yield than the arithmetic sum of those of cotton and nylon as single fibers. The char yield of the nylon/cotton blends decreases when the blend contained less cellulose. But for the polyester/cotton fabrics, the blend has higher THR than the arithmetic sum of cotton and polyester as single fibers with a bit increase in the percent char yield, and its char yield increases as the cotton ratio in the blend decreases. It is illustrated that the interaction that occurs between nylon and cotton is different from that between polyester and cotton. In the case of Nomex/cotton blends, the actual HRR curve matches well with the simulated curve, and the THR and percent char yield are almost the same as the calculated data. There is nearly no interaction between Nomex and cotton components during the degradation of the blend. Overall, the results show that the decomposition process of blended fabrics is not simply the addition of the decomposition process of the component single fibers, but is in fact more complicated.