Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARISON OF RETROSPECTIVE LUMINESCENCE DOSIMETRY WITH COMPUTATIONAL MODELING IN TWO HIGHLY CONTAMINATED SETTLEMENTS DOWNWIND OF THE CHERNOBYL NPP

Abstract— The cumulative absorbed dose in bricks collected from six buildings in two heavily contaminated settlements (137Cs > 2,000 kBq m−2) located downwind of the Chernobyl Nuclear Power Plant was determined using luminescence techniques by six laboratories. The settlements, Vesnianoje in Ukraine and Zaborie in Russia, are located in, respectively, proximal and distal locations relative to the Chernobyl Nuclear Power Plant. The luminescence determinations of cumulative dose in brick, after subtraction of the natural background dose, were translated to absorbed dose in air at a Reference Location using conversion factors derived from Monte Carlo simulations of photon transport. The simulations employed source distributions inferred from contemporary soil contamination data and also took into account heterogeneity of fallout deposition. This translation enables the luminescence determinations to be compared directly with values of cumulative absorbed dose obtained by computational modeling and also other dose reconstruction methods. For each sampled location the cumulative dose was calculated using three deterministic models, two of which are based on the attenuation of dose-rate with migration of radionuclides in soil and the third on historic instrumental gamma dose-rate data. The results of the comparison of the two methods indicate overall agreement within margins of ±25%. The methodology developed is generally applicable and adaptable to areas contaminated by much lower levels of radioactive fallout in which brick buildings are found.
Serum concentrations of adiponectin, leptin, resistin, ghrelin and insulin and their association with obesity indices in obese normo- and hypertensive patients – pilot study

Introduction Hypertension often coexists with obesity. Adipokines, ghrelin and insulin play important roles in the pathogenesis of both diseases. The aim of this study was to compare adiponectin, leptin, resistin, insulin and ghrelin mean serum concentrations and insulin resistance (HOMA-IR) in normo- and hypertensive patients with obesity. Material and methods All included patients were divided on the following groups: non-diabetic hypertensive patients with class I obesity (group A, n = 21) and class II/III obesity (group B, n = 10), and normotensive obese (class I)patients (group C, n = 7). Correlations between obesity indices (body mass index [BMI], waist-to-hip ratio [WHR], waist circumference [WC]), HOMA-IR, and hormone and adipokine serum levels were also analyzed. Results Leptin level and HOMA-IR were significantly higher in group B compared to group C (9.74 ±3.88 ng/ml vs. 4.53 ±3.00 ng/ml; p < 0.02 and 3.30 ±1.59 vs. 1.65 ±0.41; p < 0.02, respectively). A negative correlation between WC and adiponectin level (R = –0.6275; p < 0.01) and a positive correlation between WC and insulin concentration (R = 0.5122; p< 0.05) as well as with HOMA-IR (R = 0.5228; p < 0.02) were found in group A. Negative correlations between BMI and ghrelin level (R = –0.7052; p < 0.05), WHR and adiponectin level (R = –0.6912; p < 0.05) and WHR and leptin level (R = –0.6728; p < 0.05) were observed in group B. Conclusions Insulin resistance and leptin may be important pathogenic factors in hypertensive patients with severe obesity. Indices of abdominal obesity (WC, WHR) correlate better than BMI with HOMA-IR, insulin, adiponectin and leptin serum levels in hypertensive obese patients.
Improving the Mechanical Properties of Polycarbonate Nanocomposites with Plasma‐Modified Carbon Nanofibers

The mechanical properties of polycarbonate film embedded with carbon nanofibers were studied based on plasma surface modification of carbon nanofibers by the use of polystyrene. The nanofiber surfaces were modified by various processing conditions including plasma polymerization power, nanofiber concentration, and ultrasonication time. The tensile strength and Young's modulus of the carbon nanofiber‐polycarbonate composites were then measured. The mechanical behavior of the composite was found to be affected by dispersion of the nanofibers. Higher plasma power resulted in improved mechanical strength. A maximum strength (10% increase) was achieved at a low concentration (1 wt.%) of nanofibers. The optimization of ultrasonication time indicated that the maximum strength occurred at different times for the composites with different concentrations of the modified carbon nanofibers.
Factors in narratives to questions in the short-term life review interviews of terminally ill cancer patients and utility of the questions

Abstract Objective: Although the Short-Term Life Review elevated the spiritual well-being of terminally ill cancer patients in our previous study, we have not examined what patients reviewed for each question item of it. We examined factors in narratives to questions in the Short-Term Life Review interviews of terminally ill cancer patients and utility of the questions. Method: Thirty-four terminally ill cancer patients received the Short-Term Life Review interview in which there were two sessions. In the first session patients reviewed their lives, and an interviewer made a simple album of the patient based on patients' narrative. After 1 week, there was a second session. Qualitative analysis was conducted on patients' answers to each question using computational word mining, and factors were identified. Results: Twenty patients' narratives were analyzed. “Human relationships” was identified under “important things in life. ” “Pleasant memories” were associated with “impressive memories. ” “Illness” and “marriage and divorce” were related to “turning points in the life. ” “Raising children and education” and “company or work” were identified as “roles in life. ” “Achievements at work” were identified with “pride. ” “Message to my children” was identified with “what I want to say to my family. ” “To live sincerely” and “consideration for others” were identified as “advice for the next generation. ” Patients reviewed few for topics such as “pride,” “what I want to say to my family,” “advice for the next generation,” and “summing up my life. ” Significance of results: Factors such as human relationships, raising children, and education as a role and source of pride, and concerns about children's future, were associated with elevating spiritual well-being. Question to which that patients easily answered were selected.
Connection strategies: Social capital implications of Facebook-enabled communication practices

This study assesses whether Facebook users have different ‘connection strategies,’ a term which describes a suite of Facebook-related relational communication activities, and explores the relationship between these connection strategies and social capital. Survey data (N = 450) from a random sample of undergraduate students reveal that only social information-seeking behaviors contribute to perceptions of social capital; connection strategies that focus on strangers or close friends do not. We also find that reporting more ‘actual’ friends on the site is predictive of social capital, but only to a point. We believe the explanation for these findings may be that the identity information in Facebook serves as a social lubricant, encouraging individuals to convert latent to weak ties and enabling them to broadcast requests for support or information.
Dynamic Characterization of a Fiber-Metal Laminate

The mechanical strength of a fiber-metal laminate is not so well explored at high strain rates, although its constituents are prone to exhibit such effects. In this paper, we describe an investigation of aluminium-fiber glass material using the Split Hopkinson bar device. We report on various experimental issues related to these tests, giving some emphasis to the use of high speed filming to obtain information on the specimen strain and strain rate.
DIFFERENTIATION AND PROLIFERATION OF EMBRYONIC MAST CELLS OF THE RAT

Histochemical reactions and radioautography were used to investigate the sequence of mast cell development in rat embryos. Mast cells arise ubiquitously in and are confined to the loose connective tissue in the embryo. The alcian blue-safranin reaction distinguishes between weakly sulfated and strongly sulfated mucopolysaccharides by a shift from alcian blue to safranin staining. Based on this reaction and morphologic characteristics, four stages were identified. Stage I mast cells are lymphocyte-like cells with cytoplasmic granules which invariably stain blue with the alcian blue-safranin reaction. In Stage II cells the majority of granules are alcian blue-positive, but some safranin-positive granules have appeared. Stage III mast cells are distinguished by a majority of safranin-positive cytoplasmic granules; some alcian blue-positive granules still remain. Stage IV cells contain only safranin-positive granules. Thymidine-H3 uptake and identification of mitotic figures indicates that mast cells in Stages I and II comprise a mitotic pool while those in Stages III and IV are mitotically inactive. The pattern of S35O4 incorporation and the sequence of appearance of histochemically identifiable mast cell constituents corroborates division of the proliferation and differentiation of embryonic mast cells into the four stages described above. The process of formation of mast cell granules is interpreted as reflecting the synthesis and accumulation of a heparin precursor in alcian blue positive granules followed by the synthesis and accumulation of highly N-sulfated heparin along with mast cell chymase and finally histamine in safranin-positive granules.
Lewis Phenotype of Erythrocytes and Leb‐Active Glycolipid in Serum of Pregnant Women 1

Abstract. In an attempt to provide an explanation for the previously reported effect of pregnancy on the Lewis phenotype of erythrocytes, the level of Leb‐active glycolipid in serum was compared with the reactions of erythrocytes, using samples obtained from 73 nonpregnant women, 74 women at the time of delivery, and 2 women at weekly intervals during their pregnancy. In this Swedish population, the frequency of the Le(a‐b‐) blood group increased from 11% in nonpregnant women to 36% in women at the time of delivery. Among Le(a‐b+) women of all ABO groups, those who were A1 most often became Le(b‐) during pregnancy. The change in phenotype occurred as early as the 24th week of gestation; the Leb antigen was again detectable within 6 weeks after delivery. The concentration of Leb glycolipid in serum, as measured by radioimmunoassay, decreased only slightly during pregnancy. The repartition of glycolipids, secondary to the increased ratio of lipoprotein to red cell mass that occurs during pregnancy, may account for the relative lack of Lewis glycolipid on erythrocytes.
Effects of 6-Month Sitagliptin Treatment on Glucose and Lipid Metabolism, Blood Pressure, Body Weight and Renal Function in Type 2 Diabetic Patients: A Chart-Based Analysis

Background Sitagliptin is one of the dipeptidyl peptidase-4 (DPP-4) inhibitors which prevent the inactivation of incretins, increasing the endogenous active incretin levels. Incretins stimulate insulin secretion from pancreatic β-cells and inhibit glucagon secretion from pancreatic α-cells, which is favorable for the treatment of diabetes. Sitagliptin is released on December, 2009, in Japan. We retrospectively studied effects of 6-month-treatment with sitagliptin on glucose and lipid metabolism, blood pressure, body weight and renal function in patients with type 2 diabetes by a chart-based analysis. Methods We retrospectively studied 220 type 2 diabetic patients who have taken sitagliptin for 6 months by a chart-based analysis. Subjects studied include patients treated with sitagliptin monotherapy, sitagliptin add-on therapy, and switching from glinide to sitagliptin. We selected patients who have both data before and after 6-month sitagliptin treatment and compared the data before the sitagliptin treatment with the data at 6 month after the sitagliptin treatment started. Body weight, blood pressure, plasma glucose, hemoglobin A1c (HbA1c), serum lipids, and estimated glomerular filtration rate in type 2 diabetic patients were measured almost at the same time points before and after 6-month-treatment with sitagliptin. Results Body weight was significantly reduced after 6-month sitagliptin treatment by 0.8 kg. HbA1c levels were also significantly decreased after the sitagliptin treatment by 0.6%. We found a significant and negative correlation between change in body weight and body mass index at baseline. We also observed a significant and negative correlation between change in HbA1c and HbA1c levels at baseline. The number of patients who showed the absence of urinary glucose was significantly increased after the sitagliptin treatment.
Power Electronic Transformer Technology for Traction Applications – An Overview

Combining modern high-power semiconductor devices with constantly improving magnetic materials opens up the possibility to replace bulky low-frequency transformers with a new medium voltage medium frequency conversion structure. While there are still challenges to be addressed related to these so called power electronic transformers, a steadily increasing development effort is evident and considered in various contexts. Traction applications seem to be the first ones where proliferation of these galvanically isolated power electronic converters is expected. In this application field, substantial weight and volume reduction can be achieved while providing additional functionality at the same time. In this paper a survey of recent R&D efforts in this field is presented.
Glutamate‐like Immunoreactivity in Retinal Terminals of the Mouse Suprachiasmatic Nucleus

With a view to identifying the neurotransmitter content of retinal terminals within the mouse suprachiasmatic nucleus, a highly specific antiserum to glutaraldehyde‐coupled glutamate was used in a postembedding immunogold procedure at the ultrastructural level. Retinal terminals were identified by cholera toxin–horseradish peroxidase transported anterogradely from the retina and reacted with tetramethyl benzidine/tungstate/H2O2, or by their characteristically pale and distended mitochondria with irregular cristae. Controls included model ultrathin sections containing high concentrations of various amino acids. Alternate serial sections were labelled with anti‐glutamate and anti‐γ‐aminobutyric acid (GABA). Data were analysed by computer‐assisted image analysis. Density of glutamate labelling (gold particles per μm2) on whole retinal terminals was > 3 times higher than that on postsynaptic dendrites, and > 5 times higher than that on miscellaneous non‐retinal non‐glutamatergic terminals in the suprachiasmatic nucleus. The overall density of gold particles over retinal terminals was ∼ 3 times higher than that over GABAergic terminals, in which glutamate‐like immunoreactivity was mainly mitochondrial. Labelling of vesicles in retinal terminals was almost 5 times greater than the apparent labelling of vesicles in GABAergic terminals, underscoring the location of transmitter glutamate within synaptic vesicles in retinal terminals. In the retino‐recipient region of the suprachiasmatic nucleus there was also a small population of non‐retinal glutamatergic terminals. Their overall immunoreactivity was similar to or exceeded that of retinal terminals, but morphological features clearly distinguished between these two types of glutamate‐containing terminals. The present results indicate that the vast majority of retinal terminals may use glutamate as a transmitter, in keeping with electrophysiological and neuropharmacological data from other sources. The possibility of cotransmitters within retinal terminals, suggested by the presence of dense‐core vesicles among the glutamate‐containing synaptic vesicles, has still to be addressed.
Increased cell proliferation and contractility of prostate in insulin resistant rats: Linking hyperinsulinemia with benign prostate hyperplasia

Obesity, dyslipidemia, Hyperinsulinemia, and insulin resistance (IR) are key features of metabolic syndrome and are considered as risk factors for benign prostatic hyperplasia (BPH) as well as type 2 diabetes. The present study was aimed to determine whether or not IR associated hyperinsulinemia contributes to the BPH.
Noisy Network Coding

A noisy network coding scheme for communicating messages between multiple sources and destinations over a general noisy network is presented. For multi-message multicast networks, the scheme naturally generalizes network coding over noiseless networks by Ahlswede, Cai, Li, and Yeung, and compress-forward coding for the relay channel by Cover and El Gamal to discrete memoryless and Gaussian networks. The scheme also extends the results on coding for wireless relay networks and deterministic networks by Avestimehr, Diggavi, and Tse, and coding for wireless erasure networks by Dana, Gowaikar, Palanki, Hassibi, and Effros. The scheme involves lossy compression by the relay as in the compress-forward coding scheme for the relay channel. However, unlike previous compress-forward schemes in which independent messages are sent over multiple blocks, the same message is sent multiple times using independent codebooks as in the network coding scheme for cyclic networks. Furthermore, the relays do not use Wyner-Ziv binning as in previous compress-forward schemes, and each decoder performs simultaneous decoding of the received signals from all the blocks without uniquely decoding the compression indices. A consequence of this new scheme is that achievability is proved simply and more generally without resorting to time expansion to extend results for acyclic networks to networks with cycles. The noisy network coding scheme is then extended to general multi-message networks by combining it with decoding techniques for the interference channel. For the Gaussian multicast network, noisy network coding improves the previously established gap to the cutset bound. We also demonstrate through two popular Gaussian network examples that noisy network coding can outperform conventional compress-forward, amplify-forward, and hash-forward coding schemes.
Effects of Aerobic Exercise on the Pulmonary Functions, Respiratory Symptoms and Psychological Status of People Living With HIV

Background: Pulmonary complications, respiratory symptoms and depression are common occurrences which contribute to the morbidity and mortality seen in individuals living with HIV/AIDS. This study investigated the effect of aerobic exercise on the pulmonary functions, respiratory symptoms and psychological status of people living with HIV. Methods: This study was conducted in Lagos, Nigeria from October 2014 to May 2015. Forty eligible individuals with HIV aged 18 yr and above participated, of which 33 cooperated to the end. They were recruited from the HIV/AIDS Prevention and Intervention Initiative (APIN) Clinic, Lagos University Teaching Hospital, Nigeria and were randomly assigned to either the study or the control group. The study group received aerobic exercise training three times a week for six weeks and counselling while the control group received only counselling. Pulmonary functions, respiratory symptoms and psychological status were evaluated at baseline and at six weeks. Inferential statistics of paired and independent t-test were used to analyze the data. Results: Comparison of mean changes in the pulmonary variables of the study group with those of the control group showed significant differences in all but in the respiratory rate (RR) - [Forced Expiratory Volume in one second: ,P=0.001, Forced Vital Capacity: P=0.001, Peak Expiratory Flow: P=0.001]. There were also significant differences between the mean changes in respiratory symptoms (P=0.001) and depressive symptoms (P=0.001) of study group and those of the control group. Conclusions: Aerobic exercise training significantly improved pulmonary functions as well as significantly reduced respiratory and depressive symptoms in people living with HIV.
Disruption of Persistent Nociceptive Behavior in Rats with Learning Impairment

Despite the subjective nature of pain experience with cognitive and affective dimensions, preclinical pain research has largely focused on its sensory dimension. Here, we examined the relationship between learning/memory and nociceptive behavior in rats with combined learning impairment and persistent nociception. Learning impairment was induced by bilateral hippocampal injection of a mixed Aβ solution, whereas persistent nociception produced in these rats by complete Freund’s adjuvant-induced ankle inflammation. Those rats with learning impairment showed a diminished development of thermal hyperalgesia and mechanical allodynia and a shorter time course of nociceptive behavior without alteration of their baseline nociceptive threshold. In rats with pre-established hyperalgesia and allodynia due to ankle inflammation, bilateral intra-hippocampal injection of cycloheximide (a protein synthesis inhibitor) promoted the earlier recovery of nociceptive behavior. Moreover, expression of Aβ, NR1 subunit of the N-methyl-D-aspartate receptor, and protein kinase Cγ was upregulated, whereas the choline acetyl transferase expression was downregulated, in the hippocampus, thalamus, amygdala, and/or spinal cord of rats with combined learning impairment and persistent nociception. The data indicate that learning impairment could disrupt the response to a state of persistent nociception, suggesting an important role for cognitive maladaptation in the mechanisms of chronic pain. These results also suggest that a preclinical model of combined learning impairment and persistent nociception may be useful to explore the brain mechanisms underlying the transition from acute to chronic pain.
FORCE-VELOCITY RELATIONSHIPS OF A LOCUST FLIGHT MUSCLE AT DIFFERENT TIMES DURING A TWITCH CONTRACTION

Summary 1. The force-velocity relationships during isotonic shortening were determined for the metathoracic second tergocoxal muscle of the locust Schistocerca americana (Drury). This muscle is a synchronous flight muscle. During the plateau of a tetanic contraction, the maximum shortening velocity (Vmax) determined from the force-velocity curve was 5.2 muscle lengths s" 1 (25°C) and the curvature (a/Po) was 0.62. The maximum isometric force (Po) was 36.3 N cm" 2 . 2. Early in a twitch (at times shorter than the isometric twitch rise time) the values for Vmax and curvature were similar to those during the tetanic plateau, but the curves at different times during the twitch intercepted the force axis at values less than Po- Later in the twitch, Vmex declined. 3. A variable termed degree of activation (DA) is developed as a measure of the force-generating capacity of a muscle when this may be time-varying, as throughout most of a twitch. DA is determined from the shortening velocity at an intermediate load and is the predicted intercept of the force-velocity curve with the force axis relative to the tetanic intercept. In the locust muscle, DA rose to a maximum in 2-3 ms after the end of the latent period. DA reached 80% of the tetanic value during a single twitch; during the second twitch of a pair, the peak DA reached approximately the tetanic value. After a brief plateau, DA declined approximately exponentially. The time constant of DA decay was about 14 ms.