Miracle-dz/UniFAR-FTUs huggingface dataset:
The role of coworker and supervisor support on job burnout and job satisfaction

Purpose - This study investigates the role of coworker and supervisor support on three aspects of burnout (emotional exhaustion, depersonalization, perceived lack of personal accomplishment) and job satisfaction. The authors argue that different sources of social support at work can influence these three aspects of burnout differently. Design/methodology/approach - Questionnaires were delivered to supervisors of each campus department at two state universities in South Texas asking them to encourage their employees to complete the survey. The sample consisted of 174 personnel. Findings - The results show that coworker support was negatively associated with emotional exhaustion and depersonalization but not with perceived lack of personal accomplishment while supervisor support was negatively associated with all aspects of burnout. The analysis also confirmed the direct and indirect effects of coworker and supervisor support on job satisfaction. Practical implications - Due to the detrimental consequences of burnout to employee satisfaction, organizations need to make sure that employees receive sufficient support from their coworkers and supervisors to avoid this burnout problem. Originality/value - Even though the role of social support on job burnout has been previously investigated, existing studies tended to combine three dimensions of burnout into a single measure. Using an aggregated measure of burnout as an outcome variable can limit our understanding about the role that social support plays on each individual dimension of burnout. By employing burnout as a multidimensional construct, the present study can determine whether coworker support and supervisor support can have a different impact on each of the three dimensions of burnout.
Microsatellite instability and somatic mutations in endometrial carcinomas.

Recently, microsatellite instability (MI) has been demonstrated in some types of human cancers. In this study, we attempted to determine the frequency of MI in endometrial cancers and evaluate whether replication error (RER)-positive phenotype is correlated with known genetic mutations or the aberrations of other pathways in endometrial cancers. Seventy-two primary endometrial cancers were examined for microsatellite instability. Eleven tumors (15%) had RERs at two or more microsatellite loci, suggesting that generalized MI may be a molecular manifestation of endometrial cancers. We next examined whether the MI was associated with changes in the K-ras protooncogene, p53 tumor suppressor gene, and 18q LOH, which were frequently detected in endometrial cancers. The MI did not confer the potential to produce point mutations in the K-ras gene or 18q LOH, whereas the data were insufficient to identify the correlation between MI and p53 mutations in the cancers. These results suggest the presence of multiple mutation subsets that act in a complementary fashion in endometrial cancer development.
High-Speed Visible Light Communication Using GaN-Based Light-emitting Diodes With Photonic Crystals

Recent research and progress have shown that using light-emitting diodes (LEDs) as a high-speed transmitter is a promising candidate in a high-speed data system. The photonic crystal (PhC) LED (PhCLED) can improve the performance of the devices for visible light communication (VLC) due to its unique spatial and temporal management of photonic modes. In this paper, the dynamic behaviors of PhCLEDs at both small- and large-signal modulation are studied. Room-temperature time-resolved photoluminescence (TRPL) and Raman scattering measurements were carried out to understand the photon lifetime and strain in the PhC structure. PhCLEDs demonstrate much better high-frequency performance than conventional planar LEDs. Our study also shows that the common wisdom of shrinking the mesa size of LEDs to achieve high-frequency operation has its limit since the spontaneous emission rate has to be increased accordingly to maintain high light output efficiency in VLC LEDs.
Flt-4–Positive Endothelial Cell Density and Its Clinical Significance in Non–Small Cell Lung Cancer

Purpose: Experimental studies have revealed that fms-like tyrosine kinase (Flt)-4 plays important roles in lymphangiogenesis in malignant tumors, but the clinical significance remains unclear. We assessed Flt-4 expression in tumor cells and in endothelial cells in correlation with clinical outcomes in non–small cell lung cancer (NSCLC). Experimental Design: A total of 206 consecutive patients with resected pathological stage I-IIIA NSCLC were reviewed. Expression of Flt-4 was examined immunohistochemically, and Flt-4–positive microvessels were quantitatively evaluated (Flt-4–positive endothelial cell density). Results: There was no significant correlation between Flt-4–positive endothelial cell density and any characteristic of patients including nodal metastases. A significant correlation between Flt-4–positive endothelial cell density and Flt-4 status in tumor cells was documented (P < 0.001), but there was no significant difference in the mean Flt-4–positive endothelial cell density according to vascular endothelial growth factor-C or -D status in tumor cells. The 5-year survival rate for higher Flt-4–positive endothelial cell density tumor (56.4%) was significantly lower than that of lower Flt-4–positive endothelial cell density tumor (69.0%, P = 0.046); the prognostic significance was enhanced in pIIIA-N2 patients (5-year survival rates, 18.8% for higher Flt-4–positive endothelial cell density tumor and 50.0% for lower Flt-4–positive endothelial cell density tumor, respectively; P = 0.012). A multivariate analysis confirmed that higher Flt-4–positive endothelial cell density was a significant and independent prognostic factor (P = 0.019). CD34-positive vessel density or Flt-4 status in tumor cells was not a significant prognostic factor. Conclusions: Flt-4–positive endothelial cell density, not Flt-4 status in tumor cells, was a significant prognostic factor in NSCLC.
Person-Specific SIFT Features for Face Recognition

Scale invariant feature transform (SIFT) proposed by Lowe has been widely and successfully applied to object detection and recognition. However, the representation ability of SIFT features in face recognition has rarely been investigated systematically. In this paper, we proposed to use the person-specific SIFT features and a simple non-statistical matching strategy combined with local and global similarity on key-points clusters to solve face recognition problems. Large scale experiments on FERET and CAS-PEAL face databases using only one training sample per person have been carried out to compare it with other non person-specific features such as Gabor wavelet feature and local binary pattern feature. The experimental results demonstrate the robustness of SIFT features to expression, accessory and pose variations.
Using Syntactic Analysis to Increase Efficiency in Visualizing Text Collections

Self-Organizing Maps (SOMs) are a good method to cluster and visualize large collections of documents, but they are computationally expensive. In this paper, we investigate linguistically motivated reductions on the usual bag-of-words representation, to improve efficiency. We find that reducing the document representation to heads of verb and noun phrases reduces the heavy computational cost without degrading the quality of the map, especially in combination with term reduction techniques. More severe reductions which focus on subject and object nominal phrases are not advantageous.
The Effects of a Social Skills Training Package on Social Engagement of Children With Autism Spectrum Disorders in a Generalized Recess Setting

The present study provides a preliminary evaluation of the effects of the Superheroes Social Skills program, a practice-ready, multimedia social skills program, on social engagements of elementary-age children with autism spectrum disorders (ASD). Four children with ASD between the ages of 8 and 10 with current placements in inclusive public school settings participated in an 8-week intervention utilizing the intermediate skill components of the Superheroes Social Skills program. The intervention was presented once per week for approximately 30 min in the school settings. Analysis of data suggests that social engagements of participants during generalized recess periods increased following the introduction of intervention. Data on frequency of initiations and responses, as well as sociometric outcomes, were also collected as a secondary dependent variable and are discussed. Results suggest that pullout social skills training may result in effects that are generalized to more naturalistic settings. Limitations of the current study and suggestions for future research are reviewed.
Prevalence of cerebral aneurysms in patients with persistent primitive trigeminal artery.

OBJECT The aim of this study was to determine the prevalence of cerebral saccular aneurysms in patients with persistent primitive trigeminal artery (PPTA). The prevalence of cerebral saccular aneurysms in patients with PPTA previously has been reported to be 14 to 32%, but this rate range is unreliable because it is based on collections of published case reports rather than a series of patients chosen in an unbiased manner. METHODS The authors retrospectively evaluated their own series of 34 patients with PPTA to determine the prevalence of cerebral aneurysms in this population. The prevalence of intracranial aneurysms in patients with PPTA was approximately 3% (95% confidence interval 0-9%). CONCLUSIONS The prevalence of intracranial aneurysms in patients with PPTA is no greater than the prevalence of intracranial aneurysms in the general population.
Pose-Invariant Face Recognition Using A Single 3D Reference Model

Approaches for cross-pose face recognition can be categorized into 2D image based and 3D model based. However, only a small number of 3D model based approaches are reported although 3D information is considered crucial for cross-pose analysis. Extended from a latest face reconstruction method using a single 3D reference model, this study focuses on using the reconstructed 3D face for recognition across poses. Given a 2D face image of frontal pose, one can reconstruct its 3D model from a 3D reference face using spherical harmonics to approximate the reflectance across the given face. Experiments on the PIE database show that addition of local correspondences for pose alignment, multiple reference models considered in the reconstruction phase, and the addition of a profile pose to the gallery set can make the performance competitive to the stateof-the-art.
Effectiveness of an educational intervention to improve child feeding practices and growth in rural China: updated results at 18 months of age.

Inappropriate complementary feeding practices have led to, in part, significant disparities in growth and nutritional status between rural and urban children in China. A cluster-randomised, controlled trial was implemented in Laishui, China to assess the effectiveness of an educational intervention on caregivers' feeding practices and children's growth. Eight townships were randomly assigned to the intervention or control. Five hundred ninety-nine healthy infants were enrolled at 2-4 months old, and were followed up at ages 6, 9, 12, 15 and 18 months. The intervention group received information on enhanced home-prepared recipes and food preparation and hygiene through group training, counselling and home visit. Key outcomes were children's physical growth, caregivers' knowledge and behaviours on complementary feeding, and the infant and child feeding index (ICFI). Analysis was by intention to treat. The intervention group achieved better knowledge and practices related to complementary feeding, and significantly higher ICFI scores at each follow-up point. Children in the intervention group achieved higher z-scores for weight-for-age (WAZ) and weight-for-height (WHZ) than the control (0.18 vs. 0.01 and 0.49 vs. 0.19, respectively) at 18 months old, and were less likely to have stunted growth (odds ratio = 0.71, 95% confidence interval: 0.53-0.94). Mixed model showed that the intervention group achieved significantly better linear growth over time, including WAZ (P = 0.016), WHZ (P = 0.030) and HAZ (P = 0.078). These results indicated that an educational intervention delivered through local health services can enhance caregivers' knowledge and practices of complementary feeding and ultimately improve children's growth.
Calling and meaningful work among student military veterans: impact on well-being and experiences on campus

CALLING AND MEANINGFUL WORK AMONG STUDENT MILITARY VETERANS: IMPACT ON WELL-BEING AND EXPERIENCES ON CAMPUS The population of military veterans in the United States is now greater than 23 million people, and the number of veterans attending college is increasing as a result of the passing of the Post-9/11 GI Bill. Very little research has examined the role of meaningful work in the experiences of student veterans who are transitioning from military service to civilian life and student life. The present study utilized a mixed-method design. Regression analyses examined the role that meaningful work and calling play in the levels of well-being reported by military veterans in college. This study also examined the role of social support in student veterans' wellbeing, and utilized qualitative research methods to gather data about student veterans' college experiences. Results indicated that calling, meaningful work and social support are significantly associated with the components of well-being. Social support was found to moderate the relationship between meaningful work and negative affect. Qualitative data revealed themes of frustration with college administrative procedures, positive regard for military service and its impact on college performance, and social relationships that are significantly impacted by
Default Risk in Equity Returns

This is the first study that uses Merton's (1974) option pricing model to compute default measures for individual firms and assess the effect of default risk on equity returns. The size effect is a default effect, and this is also largely true for the book-to-market (BM) effect. Both exist only in segments of the market with high default risk. Default risk is systematic risk. The Fama-French (FF) factors SMB and HML contain some default-related information, but this is not the main reason that the FF model can explain the cross section of equity returns. Copyright 2004 by The American Finance Association.
Adaptive probabilistic neural networks for pattern classification in time-varying environment

In this paper, we propose a new class of probabilistic neural networks (PNNs) working in nonstationary environment. The novelty is summarized as follows: 1) We formulate the problem of pattern classification in nonstationary environment as the prediction problem and design a probabilistic neural network to classify patterns having time-varying probability distributions. We note that the problem of pattern classification in the nonstationary case is closely connected with the problem of prediction because on the basis of a learning sequence of the length n, a pattern in the moment n+k, k/spl ges/1 should be classified. 2) We present, for the first time in literature, definitions of optimality of PNNs in time-varying environment. Moreover, we prove that our PNNs asymptotically approach the Bayes-optimal (time-varying) decision surface. 3) We investigate the speed of convergence of constructed PNNs. 4) We design in detail PNNs based on Parzen kernels and multivariate Hermite series.
Spinal cord gray matter atrophy correlates with multiple sclerosis disability

In multiple sclerosis (MS), cerebral gray matter (GM) atrophy correlates more strongly than white matter (WM) atrophy with disability. The corresponding relationships in the spinal cord (SC) are unknown due to technical limitations in assessing SC GM atrophy. Using phase‐sensitive inversion recovery (PSIR) magnetic resonance imaging, we determined the association of the SC GM and SC WM areas with MS disability and disease type.
DNA end sequestration by DNA‐dependent protein kinase and end joining of sterically constrained substrates in whole‐cell extracts

Extracts of Xenopus eggs and of cultured human and hamster cells have the capacity to join nonhomologous DNA ends, and all do so with similar specificity. To examine the formation of repair complexes on DNA under conditions of end joining, end‐labeled fragments were incubated with the various extracts and then subjected to DNase‐I footprinting. Human and Xenopus extracts produced footprints virtually identical to that of purified DNA‐dependent protein kinase holoenzyme (Ku plus DNA‐PKcs), with protection of the terminal 28 bp. Extracts of hamster cells were more variable, but usually produced a 16‐bp footprint, similar to that of Ku alone. In all cases a 28‐bp holoenzyme‐like footprint was associated with wortmannin‐sensitive end joining, minimal 3′‐5′ exonucleolytic resection, and a predominance of accurate end‐joining products. To determine whether the short segments of DNA occupied by Ku and DNA‐PK were sufficient to support end joining, Y‐shaped substrates were constructed in which only one arm was available for end joining. A Y substrate with a 31‐bp arm bearing a partially cohesive 3′ overhang was accurately joined by a Xenopus egg extract, whereas a substrate with a 21‐bp arm was not. Surprisingly, a human cell extract did not join the Y substrates at all. The results suggest that differences in wortmannin sensitivity and in the distribution of in vitro end‐joining products may be attributable to the variations in the levels of DNA‐PKcs in the extracts. In addition, end joining in human extracts appears to involve interactions with significantly longer segments of DNA than the ∼28 bp occupied by DNA‐PK. Environ. Mol. Mutagen. 42:279–287, 2003. © 2003 Wiley‐Liss, Inc.
THE ROLE OF THE CHOLINERGIC SYSTEM IN THIAMIN DEFICIENCY *

Metabolic encephalopathies are a group of disorders in which systemic changes alter brain function. They include hypoxia, hypoglycemia, hyperammonemia, some inborn errors of metabolism, heavy metal intoxication, and nutritional deficits such as thiamin deficiency. The metabolic encephalopathies share common clinical signs and symptoms (TABLE I) . ’ An initial loss of interest and attentiveness progresses to diminished orientation, cognition, memory, and perception; obtundation is followed by stupor, coma, and finally death. This stereotyped clinical pattern, despite diverse etiologies, suggests a common pathophysiological mechanism(s). Thiamin deficiency has been recognized as a classical model of a metabolic encephalopathy since the early 1 9 3 0 ~ . ~ ~ ’ ~ * ’ ~ Several observations support the hypothesis that impairment of cholinergic function may be an important common element in the production of metabolic encephalopathies (TABLE 2). Acetylcholine is an important neurotransmitter in both the thalamic and extrathalamic divisions of the reticular activating system, which includes the septa1 hippocampal pathway. These pathways are essential for attention, learning, memory, and ultimately consciousness. ) Acetylcholine antagonists, such as scopolamine, block these functions and produce behavioral changes that mimic those of the metabolic encephalopathies. Conditions that produce metabolic encephalopathies (i.e., thiamin deficiency: low oxygen, and low glucoses) impair transynaptic cholinergic transmission in the superior cervical ganglion without diminishing axonal conduction. Furthermore, the synthesis of acetylcholine is exquisitely sensitive to conditions that decrease cerebral metabolism. This close relation is illustrated by the proportional inhibition of acetylcholine synthesis and pyruvate oxidation, even though less than 1% of the oxidized substrate is converted to acetylcholine (FIGURE 1). This linkage persists in vivo and in vitro under a wide variety of conditions and whether glucose, pyruvate, or the ketone bodies is the precursor.This tight coupling prompted us to reexamine the role of the cholinergic system in the neurological abnormalities caused by thiamin deficiency. Although the tightness of this linkage has only recently been shown, it stimulated the first studies that related thiamin deficiency to defective acetylcholine metabolism. In 1929 Kinnersley et a1. ’ demonstrated that thiamin deficiency impaired brain pyruvate oxidation and that “an intimate relation between the symptoms and some phase of carbohydrate metabolism” existed. In 1937 Stevens suggested that “the characteristic picture of fatigue and depressions in human beri-beri may occur solely
Belonging and communicating in a bounded cosmopolitanism: the role of mobile phones in the integration of transnational migrants in Singapore

ABSTRACT The unabated influx of transnational labour migrants has been accompanied by complex societal fissures, from differential policies to the creation of isolated cultural geographies. In Singapore, citizens voice their aggravation caused by transients’ lack of acculturation, and the resultant risks posed to the cosmopolitan vision of the state. We examine the intersection of transnational acculturation with mediated communication via mobile phones within the domains of life and work. Data from in-depth qualitative interviews (75) allowed for thick descriptions. We find that, despite encountering heterotopic practices, transnational migrant workers engage in a phenomenon we label ‘bounded cosmopolitanism’, or the ability to engage in learning, enjoy economic growth, and embrace cultural hybridity, to escape the shackles of race, class, and gender. Mobile phones play a significant role in providing open participatory spaces; yet; this phenomenon signifying openness, innovation, and acceptance is restricted to organizational workspaces. We therefore conclude with comments on the implications of applying management perspectives to broader societal challenges, and propose shifting of the discourse from the bounded confines of the organization to that of society.
ICP27 Interacts with the C-Terminal Domain of RNA Polymerase II and Facilitates Its Recruitment to Herpes Simplex Virus 1 Transcription Sites, Where It Undergoes Proteasomal Degradation during Infection

ABSTRACT Herpes simplex virus 1 (HSV-1) ICP27 has been shown to interact with RNA polymerase II (RNAP II) holoenzyme. Here, we show that ICP27 interacts with the C-terminal domain (CTD) of RNAP II and that ICP27 mutants that cannot interact fail to relocalize RNAP II to viral transcription sites, suggesting a role for ICP27 in RNAP II recruitment. Using monoclonal antibodies specific for different phosphorylated forms of the RNAP II CTD, we found that the serine-2 phosphorylated form, which is found predominantly in elongating complexes, was not recruited to viral transcription sites. Further, there was an overall reduction in phosphoserine-2 staining. Western blot analysis revealed that there was a pronounced decrease in the phosphoserine-2 form and in overall RNAP II levels in lysates from cells infected with wild-type HSV-1. There was no appreciable difference in cdk9 levels, suggesting that protein degradation rather than dephosphorylation was occurring. Treatment of infected cells with proteasome inhibitors MG-132 and lactacystin prevented the decrease in the phosphoserine-2 form and in overall RNAP II levels; however, there was a concomitant decrease in the levels of several HSV-1 late proteins and in virus yield. Proteasomal degradation has been shown to resolve stalled RNAP II complexes at sites of DNA damage to allow 3′ processing of transcripts. Thus, we propose that at later times of infection when robust transcription and DNA replication are occurring, elongating complexes may collide and proteasomal degradation may be required for resolution.