Miracle-dz/UniFAR-FTUs huggingface dataset:
A Transport Layer Approach for Improving End-to-End Performance and Robustness Using Redundant Paths

Recent work on Internet measurement and overlay networks has shown that redundant paths are common between pairs of hosts and that one can often achieve better end-to-end performance by adaptively choosing an alternate path [8, 28]. In this paper, we propose an end-to-end transport layer protocol, mTCP, which can aggregate the available bandwidth of those redundant paths in parallel. By striping one flow's packets across multiple paths, mTCP can not only obtain higher end-to-end throughput but also become more robust under path failures. When some paths fail, mTCP can continue sending packets on other living paths and the recovery process normally takes only a few seconds. Because mTCP could obtain an unfair share of bandwidth under shared congestion, we integrate a shared congestion detection mechanism into our system. It allows us to dynamically detect and suppress paths with shared congestion so as to alleviate the aggressiveness problem. mTCP can also passively monitor the performance of several paths in parallel and discover better paths than the path provided by the underlying routing infrastructure. We also propose a heuristic to find disjoint paths between pairs of nodes using traceroute. We have implemented our system on top of overlay networks and evaluated it in both Planet-Lab and Emulab.
Drinking and Displacement: A Systematic Review of the Influence of Forced Displacement on Harmful Alcohol Use

This paper systematically reviews evidence about factors associated with harmful alcohol use amongst forcibly displaced persons, including refugees and internally displaced persons. Bibliographic and humanitarian-related databases were searched. The number of quantitative and qualitative studies that were screened and reviewed was 1108. Only 10 studies met inclusion criteria. Risk factors identified included gender, age, exposure to traumatic events and resulting posttraumatic stress disorder, prior alcohol consumption-related problems, year of immigration, location of residence, social relations, and postmigration trauma and stress. The evidence base was extremely weak, and there is a need to improve the quantity and quality of research about harmful alcohol use by forcibly displaced persons.
‘Coming Out Tales’: Adult Sons and Daughters' Feelings About Their Gay Father's Sexual Identity

Coming out to their children is a dilemma that concerns many gay, bisexual, and lesbian parents with children from previous heterosexual relationships. How children found out about having a father who identified himself as gay, and their feelings about their father's sexual identity, were explored through qualitative analysis of semi-structured interviews with 36 sons and daughters (aged 19 to 36 years) whose gay fathers participated in the Gay & Bisexual Parenting Survey (Barrett and Tasker, 2001). Interpretative Phenomenological Analysis revealed that awareness of their father's sexual identity was often left unspoken for various reasons, and that acceptance came about through gradual understanding as well as direct discussion. Interview data indicated the complexity of the relationship between the young adult's personal acceptance of their father's gay identity and their consideration of social context when deciding how open to be to others about their father's sexual identity. This research has varied implications for therapeutic work with gay and bisexual fathers coming out to their children from previous heterosexual relationships.
Changes in Serum Melatonin Levels in Response to Pinealectomy in the Chicken and Its Correlation With Development of Scoliosis

Study Design. Normal, sham, and groups of chickens subjected to pinealectomy from which serum melatonin levels were measured and correlated with scoliosis development in a period of 5 weeks. Objectives. To measure serum melatonin levels in chickens subjected to pinealectomy and control chickens and correlate findings with development of scoliosis. Summary of Background Data. In a previous study by others, scoliosis developed in 100% of chickens subjected to pinealectomy, and serum melatonin levels were found to be reduced. Previous results in a study by the authors showed scoliosis developing in only approximately 55% of chickens that underwent pinealectomy. Methods. Young chickens were subjected to pinealectomy. Control groups consisted of sham operation and normal groups. Radiographs and blood samples were taken at weekly intervals to monitor scoliosis development and measure serum melatonin levels using radioimmunoassay techniques. Results. Scoliosis developed in only 52% of chickens that underwent pinealectomy, but all had low levels of serum melatonin and no circadian rhythm. The chickens in the two control groups maintained normal serum melatonin levels and rhythms. Conclusions. Pinealectomy in young chickens reduces serum melatonin levels and eliminates the melatonin circadian rhythm. It can also produce scoliosis, but low levels of serum melatonin are a poor predictor of development of scoliosis
Genetic variability of respiratory complex abundance, organization and activity in mouse brain

Mitochondrial dysfunction is implicated in the etiology and pathogenesis of numerous human disorders involving tissues with high energy demand. Murine models are widely used to elucidate genetic determinants of phenotypes relevant to human disease, with recent studies of C57BL/6J (B6), DBA/2J (D2) and B6xD2 populations implicating naturally occurring genetic variation in mitochondrial function/dysfunction. Using blue native polyacrylamide gel electrophoresis, immunoblots and in‐gel activity analyses of complexes I, II, III, IV and V, our studies are the first to assess abundance, organization and catalytic activity of mitochondrial respiratory complexes and supercomplexes in mouse brain. Remarkable strain differences in supercomplex assembly and associated activity are evident, without differences in individual complexes I, II, III or IV. Supercomplexes I1III2IV2–3 exhibit robust complex III immunoreactivity and activities of complexes I and IV in D2, but with little detected in B6 for I1III2IV2, and I1III2IV3 is not detected in B6. I1III2IV1 and I1III2 are abundant and catalytically active in both strains, but significantly more so in B6. Furthermore, while supercomplex III2IV1 is abundant in D2, none is detected in B6. In aggregate, these results indicate a shift toward more highly assembled supercomplexes in D2. Respiratory supercomplexes are thought to increase electron flow efficiency and individual complex stability, and to reduce electron leak and generation of reactive oxygen species. Our results provide a framework to begin assessing the role of respiratory complex suprastructure in genetic vulnerability and treatment for a wide variety of mitochondrial‐related disorders.
Antenatal Bacterial Endotoxin Sensitizes the Immature Rat Brain to Postnatal Excitotoxic Injury

Intracerebral injection of ibotenate in newborn rodents produces brain damage that mimics that of infants with cerebral palsy. Because maternal infection may contribute to brain injury in preterm infants, we investigated brain damage after maternal inflammation and postnatal ibotenate treatment in a rat model of cerebral palsy. Pregnant rats were injected intraperitoneally with lipopolysaccharide at Days 19 and 20 of gestation. Neonates were given intracerebral injections of ibotenate at postnatal Day 4 and were then killed at Day 9. Lesion sizes were measured by cresyl violet staining, and microglial activation, astrogliosis, and myelination were evaluated by immunohistochemistry. The lipopolysaccharide groups had larger cortical and white matter lesions than the control group; they also had significantly greater microglial activation and astrogliosis and less white matter myelination in the lesioned hemispheres compared with the controls. Thus, maternal endotoxin exposure may affect prenatal development of the offspring and modulate the subsequent development of excitotoxic brain lesions. These results demonstrate the critical influence of prenatal immune events on neonatal central nervous system vulnerability and provide a model for studying the pathophysiology of cerebral damage in preterm infants and, specifically, the interplay between brain inflammation and excitotoxicity.
Mapping the Field over 40 Years

Welcome to this special 40th Anniversary Edition of Educational Management Administration & Leadership. This issue features review papers from leading academics on six of the major and enduring themes in our field, and is timed to coincide with the 40th Anniversary of BELMAS (British Educational Leadership, Management and Administration Society), which owns the journal. EMAL’s first issue was published in June 1972 and it was initially published only twice a year, with the title of ‘Educational Administration’. It expanded to three issues a year in 1982, four in 1990 and six in 2009. BELMAS was founded just after the journal, an anomaly that is explained partly by the lead time taken to set up the Society, following initial discussions in 1970 (Glatter, 2004). This joint initiative may also be regarded as the start of the academic field of educational leadership and management in the UK. The articles in the journal may also be seen as a barometer for the changing emphases within the field over this 40 year period. We are grateful to Derek Glover, who has prepared a full content analysis of all EMAL volumes, to underpin this extended editorial. The analysis codes articles by decade, using four criteria:
Salt Use Behaviours of Ghanaians and South Africans: A Comparative Study of Knowledge, Attitudes and Practices

Salt consumption is high in Africa and the continent also shares the greatest burden of hypertension. This study examines salt-related knowledge, attitude and self-reported behaviours (KAB) amongst adults from two African countries—Ghana and South Africa—which have distributed different public health messages related to salt. KAB was assessed in the multinational longitudinal World Health Organisation (WHO) study on global AGEing and adult health (WHO-SAGE) Wave 2 (2014–2015). Respondents were randomly selected across both countries—Ghana (n = 6746; mean age 58 years old; SD 17; 41% men; 31% hypertensive) and South Africa (n = 3776, mean age 54 years old; SD 17; 32% men; 45% hypertensive). South Africans were more likely than Ghanaians to add salt to food at the table (OR 4.80, CI 4.071–5.611, p < 0.001) but less likely to add salt to food during cooking (OR 0.16, CI 0.130–0.197, p < 0.001). South Africans were also less likely to take action to control their salt intake (OR 0.436, CI 0.379–0.488, p < 0.001). Considering the various salt reduction initiatives of South Africa that have been largely absent in Ghana, this study supports additional efforts to raise consumer awareness on discretionary salt use and behaviour change in both countries.
Identifying Mechanisms Through Which Preschool Problem Behavior Influences Academic Outcomes

Given theoretical and empirical support for the importance of peer play within the preschool classroom to early learning, the present study tested the hypothesis that associations between teacher-reported problem behavior and academic skills were mediated by difficulties in peer play (disruptive and disconnected play), for a representative sample (N = 507 children across 46 classrooms) enrolled in a large urban Head Start program. The study also tested whether mediation was moderated by child sex (e.g., whether the mechanism through which problem behavior was associated with learning differed for boys and girls) controlling for the multilevel nature of these data. Findings from structural equation models provided evidence for partial mediation, whereby associations between internalizing behavior and academic skills were partially explained through their effects on disconnected play; however, mediation was present for girls only. Implications for theory, research, and practice are discussed as they support low-income children’s social and academic development through the context of peer play.
Prelude and Postlude to the Self

Erikson's theory of psychosocial development views ego identity achievement to be a crucial period in one's life. Although the theory generated a great deal of interest for a time, current models of the self-concept tend to ignore it. This study examined the relationships between Erikson's notion of identity status and several current self-related variables hypothesized to be antecedents and consequences of achieved identity. Degree of parental care and trust predicted identity achievement, which in turn predicted secure attachment and vitality. Identity achievement was also associated with measures of ego strength and development and with discrepancies between actual and ideal selves. Implications of Erikson's theory for modern views of the self are discussed.
Complication incidence of two implant systems up to six years: a comparison between internal and external connection implants

Purpose This study was conducted to compare the cumulative survival rates (CSRs) and the incidence of postloading complications (PLCs) between a bone-level internal connection system (ICS-BL) and an external connection system (ECS). Methods The medical records of patients treated with either a ICS-BL or ECS between 2007 and 2010 at Asan Medical Center were reviewed. PLCs were divided into two categories: biological and technical. Biological complications included >4 mm of probing pocket depth, thread exposure in radiographs, and soft tissue complications, whereas technical complications included chipping of the veneering material, fracture of the implant, fracture of the crown, loosening or fracture of the abutment or screw, loss of retention, and loss of access hole filling material. CSRs were determined by a life-table analysis and compared using the log-rank chi-square test. The incidence of PLC was compared with the Pearson chi-squared test. Results A total of 2,651 implants in 1,074 patients (1,167 ICS-BLs in 551 patients and 1,484 ECSs in 523 patients) were analyzed. The average observation periods were 3.4 years for the ICS-BLs and 3.1 years for the ECSs. The six-year CSR of all implants was 96.1% (94.9% for the ICS-BLs and 97.1% for the ECSs, P=0.619). Soft tissue complications were more frequent with the ECSs (P=0.005) and loosening or fracture of the abutment or screw occurred more frequently with the ICS-BLs (P<0.001). Conclusions Within the limitations of this study, the ICS-BL was more prone to technical complications while the ECS was more vulnerable to biological complications. Graphical Abstract
The Relationship Between Working Memory, Inhibition, and Performance on the Wisconsin Card Sorting Test in Children With and Without ADHD

The Wisconsin Card Sorting Test (WCST) has frequently been used to assess executive functions in children with attention deficit hyperactivity disorder (ADHD). We first compared the performance of 15 children with ADHD to 15 children of a control group (age range 6 to 11) on the WCST and then examined the relationship among working memory, inhibition, age, IQ, and scores from this test. When age and IQ were included as covariates, children with and without ADHD did not differ on the perseverative errors (PE) score, but the ADHD group made significantly more failure to maintain set errors (FTMS). Partial correlations revealed that working memory was significantly correlated with PE but was fully mediated by age and IQ. Age and IQ had no effect on the significant correlation between inhibition and FTMS. Clinicians are encouraged to interpret the results of this test with caution when including it in an assessment for ADHD.
Estrogens and urinary-tract infection.

The effects of estrogen on the risk of urinary-tract infection (UTI) in women has been the subject of many studies in both humans and experimental animals. Often, these studies have come to seemingly contradictory results: some have suggested an increased risk attributable to estrogen and others that estrogens may be preventative. In part, this confusion arises because the physiological effects of estrogen on different anatomic parts of the urinary tract differ depending on the specific effect and the outcome measured. For example, in the absence of estrogen, the periurethral and vaginal microflora, which is usually predominated by hydrogen peroxide-producing lactobacilli and few Escherichia coli, changes dramatically to a flora with few or no lactobacilli but many E. coli [1]. This change in flora is associated with a markedly increased risk of recurrent E. colibladder infections. In a randomized, placebo-controlled trial of topical intravaginal estrogen cream in such women, both the reestablishment of the normal lactobacillus-dominant vaginal flora and reduced rates of UTI were demonstrated in estro-
Excluding Induced Subdivisions of the Bull and Related Graphs

For any graph H, let Forb*(H) be the class of graphs with no induced subdivision of H. It was conjectured in [J Graph Theory, 24 (1997), 297–311] that, for every graph H, there is a function fH: ℕ→ℝ such that for every graph G∈Forb*(H), χ(G)≤fH(ω(G)). We prove this conjecture for several graphs H, namely the paw (a triangle with a pendant edge), the bull (a triangle with two vertex‐disjoint pendant edges), and what we call a “necklace,” that is, a graph obtained from a path by choosing a matching such that no edge of the matching is incident with an endpoint of the path, and for each edge of the matching, adding a vertex adjacent to the ends of this edge. © 2011 Wiley Periodicals, Inc. J Graph Theory 71:49–68, 2012
Behavior Online: Does Anonymous Computer Communication Reduce Gender Inequality?

Two studies examined dominance and self-stereotyping in mixed-sex groups who had online discussions. Gender differences in dominance varied as a function of several contextual variables: individuation, the accessibility of gender stereotypes, and the fit between group task and stereotype. Results of the second study indicate that only when group members are depersonalized (anonymous and not individuated) does stereotype activation produce gender-stereotypic behavior. However, the nature of stereotypic behavior is moderated by the fit between group task and stereotypes, such that men dominate when the topic is masculine but not when it is feminine. These findings do not support suggestions that the anonymity offered by online communication would lead to equalization. Instead, results confirm predictions from a social identity model of deindividuation effects that social effects of anonymity and identifiability in (online) groups depend on contextual factors such as stereotype accessibility and fit.
Microbiological diagnosis of empyema in children: comparative evaluations by culture, polymerase chain reaction, and pneumococcal antigen detection in pleural fluids.

BACKGROUND Pleural empyema is an increasingly reported complication of pneumonia in children. Microbiological diagnostic tests for empyema by culture frequently have false-negative results due to previous administration of antibiotics. Molecular diagnosis by broad-range 16S ribosomal DNA (rDNA) polymerase chain reaction (PCR) and rapid pneumococcal antigen detection are reliable tools, but their diagnostic value has not been clearly established for pleural fluid samples. Pneumococcal antigen detection has only been validated for urine and cerebrospinal fluid samples. METHODS Over 4 years, pleural fluid specimens were collected from 78 children with pleural empyema. Standard culture, pneumococcal antigen detection by latex agglutination (Pastorex; Bio-Rad) and immunochromatographic testing (Binax NOW Streptococcus pneumoniae), and 16S rDNA PCR were performed on these specimens. Pneumococcal identification by 16S rDNA PCR and sequencing was confirmed by pneumolysin PCR. RESULTS Of the 78 cases of pleural empyema, 60 (77%) were microbiologically documented by culture or 16S rDNA PCR. Of the 40 pneumococcal empyema cases, 17 (43%) were only diagnosed by PCR and 23 with PCR and culture. The sensitivity and specificity of the latex antigen detection (with the use of culture and/or PCR as the test standard) were 90% and 95%, respectively. The immunochromatographic test detected pneumococcal antigens in 3 additional specimens for which latex agglutination results were negative, thereby increasing the sensitivity of antigen detection. CONCLUSIONS Pneumococcal antigen detection in pleural fluid specimens from children provides a rapid and sensitive method of diagnosis of pneumococcal empyema, which can be confirmed by specific pneumolysin PCR when culture results are negative. Broad-range 16S rDNA PCR has value in detecting bacterial agents responsible for culture-negative pleural empyema.
From the Outside-In: The Francisella tularensis Envelope and Virulence

Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal disease, tularemia. Many studies have been performed to identify and characterize the virulence factors that F. tularensis uses to infect a wide variety of hosts and host cell types, evade immune defenses, and induce severe disease and death. This review focuses on the virulence factors that are present in the F. tularensis envelope, including capsule, LPS, outer membrane, periplasm, inner membrane, secretion systems, and various molecules in each of aforementioned sub-compartments. Whereas, no single bacterial molecule or molecular complex single-handedly controls F. tularensis virulence, we review here how diverse bacterial systems work in conjunction to subvert the immune system, attach to and invade host cells, alter phagosome/lysosome maturation pathways, replicate in host cells without being detected, inhibit apoptosis, and induce host cell death for bacterial release and infection of adjacent cells. Given that the F. tularensis envelope is the outermost layer of the bacterium, we highlight herein how many of these molecules directly interact with the host to promote infection and disease. These and future envelope studies are important to advance our collective understanding of F. tularensis virulence mechanisms and offer targets for future vaccine development efforts.
A Path Analysis Study of School Culture and Teachers' Organisational Commitment

In this study, the direct and indirect relations between school culture and the organisational commitment of primary school teachers were analyzed. The subjects of the research consisted of primary school teachers who worked at a district in Istanbul in the academic year 2007–2008. The sampling group was defined by the cluster sampling method. In total 200 teachers participated. Two scales were used to collect data, the organisational commitment scale (OCS) and the school culture scale (SCS). Linear regression and path analysis were used to explain the influence of school culture on organisational commitment, and LISREL 7 was used as a structural equation model. The findings indicated that although there was a positive correlation between school culture and organisational commitment, the direct effect of school culture on organisational commitment was not meaningful.