Miracle-dz/UniFAR-FTUs huggingface dataset:
SUPPRESSION OF STAR FORMATION IN NGC 1266

NGC 1266 is a nearby lenticular galaxy that harbors a massive outflow of molecular gas powered by the mechanical energy of an active galactic nucleus (AGN). It has been speculated that such outflows hinder star formation (SF) in their host galaxies, providing a form of feedback to the process of galaxy formation. Previous studies, however, indicated that only jets from extremely rare, high-power quasars or radio galaxies could impart significant feedback on their hosts. Here we present detailed observations of the gas and dust continuum of NGC 1266 at millimeter wavelengths. Our observations show that molecular gas is being driven out of the nuclear region at yr−1, of which the vast majority cannot escape the nucleus. Only 2 M☉ yr−1 is actually capable of escaping the galaxy. Most of the molecular gas that remains is very inefficient at forming stars. The far-infrared emission is dominated by an ultra-compact (≲ 50 pc) source that could either be powered by an AGN or by an ultra-compact starburst. The ratio of the SF surface density (ΣSFR) to the gas surface density () indicates that SF is suppressed by a factor of ≈50 compared to normal star-forming galaxies if all gas is forming stars, and ≈150 for the outskirt (98%) dense molecular gas if the central region is powered by an ultra-compact starburst. The AGN-driven bulk outflow could account for this extreme suppression by hindering the fragmentation and gravitational collapse necessary to form stars through a process of turbulent injection. This result suggests that even relatively common, low-power AGNs are able to alter the evolution of their host galaxies as their black holes grow onto the M–σ relation.
Unsupervised Concept-to-text Generation with Hypergraphs

Concept-to-text generation refers to the task of automatically producing textual output from non-linguistic input. We present a joint model that captures content selection ("what to say") and surface realization ("how to say") in an unsupervised domain-independent fashion. Rather than breaking up the generation process into a sequence of local decisions, we define a probabilistic context-free grammar that globally describes the inherent structure of the input (a corpus of database records and text describing some of them). We represent our grammar compactly as a weighted hypergraph and recast generation as the task of finding the best derivation tree for a given input. Experimental evaluation on several domains achieves competitive results with state-of-the-art systems that use domain specific constraints, explicit feature engineering or labeled data.
On Breakthroughs, Deadlines, and the Nature of Progress: Contracting for Multistage Projects∗

We study the optimal incentive schemes for multistage projects. Staged financing, pervasive in both venture capital and research funding, arises as a feature of the optimal contract. The nature of progress plays an important role. When progress is tangible, incentives are provided through a series of deadlines and a reward scheme that decreases over time. Early progress in one stage gives the agent more time and funding to complete the next one. When progress is intangible, the optimal contract involves a soft deadline wherein the principal guarantees funding up to a certain date – if the agent reports progress at that date, then the principal gives him a relatively short deadline to complete the project – if not, then a probationary phase begins in which the project is terminated at a constant rate until progress is reported. Implications for welfare and project design are explored. JEL Classification: J41, L14, M55, D82
The limits of freedom: migration as a space of freedom and loneliness among Afghan unaccompanied migrant youth

ABSTRACT This article examines how unaccompanied minors from Afghanistan experience migration as a space of both freedom and loneliness situated between competing moral frameworks: family projects, neoliberal discourses of independence, and a quest for new ways of being. While migration is devised as a family strategy to financially sustain the household, it also creates new desires for young people: to study, to have fun, and to fulfil individual goals. Drawing on long-term ethnographic fieldwork conducted in the UK, I analyse how youth find themselves caught in moments of moral crisis as both an ethical dilemma and an experience of self-transformation – caused by the tensions between family expectations, social policies, and a search for independence. I argue that young people often struggle to find the moral ground to exercise freedom and to make the good choice, without the guidance of their parents and within neoliberal politics of self-governance. This article considers youth’s aspirations and imaginaries of ‘good life’ within different communities of belonging, and it highlights the importance of the role of kinship for understanding how youth conceptualise their future, and ultimately exercise choice.
Understanding motivational structures that differentially predict engagement and achievement in middle school science

ABSTRACT Middle school has been documented as the period in which a drop in students’ science interest and achievement occurs. This trend indicates a lack of motivation for learning science; however, little is known about how different aspects of motivation interact with student engagement and science learning outcomes. This study examines the relationships among motivational factors, engagement, and achievement in middle school science (grades 6–8). Data were obtained from middle school students in the United States (N = 2094). The theoretical relationships among motivational constructs, including self-efficacy, and three types of goal orientations (mastery, performance approach, and performance avoid) were tested. The results showed that motivation is best modeled as distinct intrinsic and extrinsic factors; lending evidence that external, performance based goal orientations factor separately from self-efficacy and an internal, mastery based goal orientation. Second, a model was tested to examine how engagement mediated the relationships between intrinsic and extrinsic motivational factors and science achievement. Engagement mediated the relationship between intrinsic motivation and science achievement, whereas extrinsic motivation had no relationship with engagement and science achievement. Implications for how classroom practice and educational policy emphasize different student motivations, and in turn, can support or hinder students’ science learning are discussed.
Absolute Exponential Stability of Recurrent Neural Networks With Generalized Activation Function

In this paper, the recurrent neural networks (RNNs) with a generalized activation function class is proposed. In this proposed model, every component of the neuron's activation function belongs to a convex hull which is bounded by two odd symmetric piecewise linear functions that are convex or concave over the real space. All of the convex hulls are composed of generalized activation function classes. The novel activation function class is not only with a more flexible and more specific description of the activation functions than other function classes but it also generalizes some traditional activation function classes. The absolute exponential stability (AEST) of the RNN with a generalized activation function class is studied through three steps. The first step is to demonstrate the global exponential stability (GES) of the equilibrium point of original RNN with a generalized activation function being equivalent to that of RNN under all vertex functions of convex hull. The second step transforms the RNN under every vertex activation function into neural networks under an array of saturated linear activation functions. Because the GES of the equilibrium point of three systems are equivalent, the next stability analysis focuses on the GES of the equilibrium point of RNN system under an array of saturated linear activation functions. The last step is to study both the existence of equilibrium point and the GES of the RNN under saturated linear activation functions using the theory of M-matrix. In the end, a two-neuron RNN with a generalized activation function is constructed to show the effectiveness of our results.
Evaluation of the Effect of Neptune Krill Oil on Chronic Inflammation and Arthritic Symptoms

Objectives: a) To evaluate the effect of Neptune Krill Oil (NKO™) on C-reactive protein (CRP) on patients with chronic inflammation and b) to evaluate the effectiveness of NKO™ on arthritic symptoms. Methods: Randomized, double blind, placebo controlled study. Ninety patients were recruited with confirmed diagnosis of cardiovascular disease and/or rheumatoid arthritis and/or osteoarthritis and with increased levels of CRP (>1.0 mg/dl) upon three consecutive weekly blood analysis. Group A received NKO™ (300 mg daily) and Group B received a placebo. CRP and Western Ontario and McMaster Universities (WOMAC) osteoarthritis score were measured at baseline and days 7, 14 and 30. Results: After 7 days of treatment NKO™ reduced CRP by 19.3% compared to an increase by 15.7% observed in the placebo group (p = 0.049). After 14 and 30 days of treatment NKO™ further decreased CRP by 29.7% and 30.9% respectively (p < 0.001). The CRP levels of the placebo group increased to 32.1% after 14 days and then decreased to 25.1% at day 30. The between group difference was statistically significant; p = 0.004 at day 14 and p = 0.008 at day 30. NKO™ showed a significant reduction in all three WOMAC scores. After 7 days of treatment NKO™, reduced pain scores by 28.9% (p = 0.050), reduced stiffness by 20.3% (p = 0.001) and reduced functional impairment by 22.8% (p = 0.008). Conclusion: The results of the present study clearly indicate that NKO™ at a daily dose of 300 mg significantly inhibits inflammation and reduces arthritic symptoms within a short treatment period of 7 and 14 days.
Chromatic and Achromatic Spatial Resolution of Local Field Potentials in Awake Cortex

Local field potentials (LFPs) have become an important measure of neuronal population activity in the brain and could provide robust signals to guide the implant of visual cortical prosthesis in the future. However, it remains unclear whether LFPs can detect weak cortical responses (e.g., cortical responses to equiluminant color) and whether they have enough visual spatial resolution to distinguish different chromatic and achromatic stimulus patterns. By recording from awake behaving macaques in primary visual cortex, here we demonstrate that LFPs respond robustly to pure chromatic stimuli and exhibit ∼2.5 times lower spatial resolution for chromatic than achromatic stimulus patterns, a value that resembles the ratio of achromatic/chromatic resolution measured with psychophysical experiments in humans. We also show that, although the spatial resolution of LFP decays with visual eccentricity as is also the case for single neurons, LFPs have higher spatial resolution and show weaker response suppression to low spatial frequencies than spiking multiunit activity. These results indicate that LFP recordings are an excellent approach to measure spatial resolution from local populations of neurons in visual cortex including those responsive to color.
Somatostatin, an inhibitor of ACTH secretion, decreases cytosolic free calcium and voltage-dependent calcium current in a pituitary cell line

Somatostatin is a neurohormone peptide that inhibits a variety of secretory responses in different cell types. We have investigated the effects of somatostatin on calcium current and intracellular free calcium in AtT-20 cells, a pituitary tumor line in which the inhibitory actions of this peptide have been well characterized. At concentrations similar to those that inhibit adrenocorticotropic hormone (ACTH) release, somatostatin and its analogs reduced the levels of intracellular free calcium (as measured by the Quin-2 technique). Nifedipine and other blockers of voltage-dependent calcium channels also reduced cytosolic calcium levels. The effects of somatostatin and nifedipine were not additive, suggesting that somatostatin might inhibit calcium channels. Experiments using the whole-cell patch-clamp technique showed that somatostatin reduces voltage-dependent calcium current. The effects of somatostatin on cytosolic calcium and calcium current appear to be independent of its ability to reduce secretagogue- stimulated cAMP accumulation in these cells. We propose that the somatostatin-induced decrease in cytosolic calcium concentrations and the voltage-dependent calcium current are one of the mechanisms by which somatostatin suppresses ACTH release in AtT-20 cells.
Intentional Attunement: Mirror Neurons and the Neural Underpinnings of Interpersonal Relations

The neural circuits activated in a person carrying out actions, expressing emotions, and experiencing sensations are activated also, automatically via a mirror neuron system, in the observer of those actions, emotions, and sensations. It is proposed that this finding of shared activation suggests a functional mechanism of “embodied simulation” that consists of the automatic, unconscious, and noninferential simulation in the observer of actions, emotions, and sensations carried out and experienced by the observed. It is proposed also that the shared neural activation pattern and the accompanying embodied simulation constitute a fundamental biological basis for understanding another's mind. The implications of this perspective for psychoanalysis are discussed, particularly regarding unconscious communication, projective identification, attunement, empathy, autism, therapeutic action, and transference-countertransference interactions.
The O-Ring Theory of Economic Development

This paper proposes a production function describing processes subject to mistakes in any of several tasks. It shows that high-skill workers—those who make few mistakes—will be matched together in equilibrium, and that wages and output will rise steeply in skill. The model is consistent with large income differences between countries, the predominance of small firms in poor countries, and the positive correlation between the wages of workers in different occupations within enterprises. Imperfect observability of skill leads to imperfect matching and thus to spillovers, strategic complementarity, and multiple equilibria in education.
Proteomic Identification of Proteins Differentially Expressed in Response to Resveratrol Treatment in Middle Cerebral Artery Occlusion Stroke Model

ABSTRACT Resveratrol has a neuroprotective effect against cerebral ischemia. The objective of this study was to identify proteins that are differentially expressed in the cerebral cortex of vehicle- and resveratrol-treated animals during ischemic injury. Focal cerebral ischemia was induced as middle cerebral artery occlusion (MCAO) in male rats. Rats were treated with vehicle or resveratrol before MCAO, and cerebral cortex was collected 24 hr after MCAO. Cerebral cortex proteins were identified by two-dimensional gel electrophoresis and mass spectrometry. Several proteins were identified as differentially expressed between vehicle- and resveratrol-treated animals. Among these proteins, expression of peroxiredoxin-5, isocitrate dehydrogenase [NAD+], apolipoprotein A-I and ubiquitin carboxy terminal hydrolase L1 was decreased in the vehicle-treated group, whereas resveratrol attenuated the injury-induced decrease in expression of these proteins. However, expression of collapsing response mediator protein 2 was increased in the vehicle-treated group, whereas resveratrol prevented the injury-induced increase in the expression of this protein. These findings suggest that resveratrol modulates the expression of various proteins that associated with oxidative stress and energy metabolism in focal cerebral ischemia.
Cytotoxicity on Human Cancer Cells of Ophidiacerebrosides Isolated from the African Starfish Narcissia canariensis

The starfish Narcissia canariensis harvested from the coasts off Dakar, Senegal, was investigated for glycolipids (GL). This report deals with the isolation, characterization and biological activity of a fraction F13-3 separated from the GL mixture and selected according to its ability to inhibit KB cell proliferation after 72 hours of treatment. Firstly, a GL mixture F13 was obtained that accounted for 1.36% of starfish biomass (dry weight) and 0.36% of total lipids. The fraction F13-3 obtained from F13 contained three homologous GL identified as peracetylated derivatives on the basis of chemical and spectroscopic evidence. These contained a β-glucopyranoside as sugar head, a 9-methyl-branched 4,8,10-triunsaturated long-chain aminoalcohol as sphingoid base and amide-linked 2-hydroxy fatty acid chains. The majority (63%) had an amide-linked 2-hydroxydocosanoic acid chain and was identified as the ophidiacerebroside-C, firstly isolated from the starfish Ophidiaster ophidiamus. The minor components of F13-3 differed by one more or one less methylene group, and corresponded to ophidiacerebroside-B and -D. We found that F13-3 displayed an interesting cytotoxic activity over 24 hours on various adherent human cancerous cell lines (multiple myeloma, colorectal adenocarcinoma and glioblastoma multiforme) with an IC50 of around 20 μM.
A motivation treatment to enhance goal engagement in online learning environments: Assisting failure-prone college students with low optimism.

Motivation treatments to enhance goal engagement can improve academic outcomes for college students with single academic risk factors (Hamm, Perry, Chipperfield, Heckhausen, & Parker, 2016), but their efficacy remains unexamined for students with multiple risk factors in online learning environments. In a pre-post, randomized treatment study (n 628), a theory-based goal engagement treatment (Heckhausen, Wrosch, & Schulz, 2010) was administered online to college students who varied in high school grades (HSG; low, high) and optimism (low, high). For students with co-occurring risk factors (low HSG–low optimism), the goal engagement treatment (vs. no-treatment) improved performance by a full letter grade on three posttreatment class tests in a two-semester course. The treatment also increased the odds of two-semester course completion by 89% for low HSG–low optimism students. Findings advance the literature in showing that a scalable and theory-based goal engagement treatment can assist college students with multiple academic risk factors.
Failed Cell Migration and Death of Purkinje Cells and Deep Nuclear Neurons in the weaver Cerebellum

The mouse neurological mutant weaver has an atrophic cerebellar cortex with deficits in both Purkinje and granule cell number. Although granule cells are known to die postnatally shortly after their final cell division, the cause of the Purkinje cell deficit (cell death vs lack of production) is unknown. We report here a quantitative analysis of large cerebellar neurons of theweaver mutant during postnatal development. We explored the hypothesis that the cells of the entire cerebellar anlage were affected by the mutation by including in our study the neurons of the deep cerebellar nuclei (DCN). Our analysis reveals that in homozygousweaver mutants (1) the DCN are displaced laterally, display an abnormal anatomy, and suffer a 20–25% decrease in neuron number; (2) this numerical deficit is located in medial regions, similar to the localization of cortical deficits in both Purkinje and granule cells; (3) pyknotic figures are present in the juvenile DCN and in the Purkinje cell layer; and (4) the majority of cell death in these populations occurs not in medial regions where the numerical deficits are observed, but rather laterally where adult cell number is nearly normal. These results lead us to propose that the completeweaver phenotype includes a failure of the cell movements that lead to the fusion of the bilateral cerebellar anlage, and that this failure to migrate properly leaves some of the Purkinje cells and DCN neurons in a position where they are unable to make appropriate connections, leading to their death. In addition to implications for normal development, these observations suggest thatweaver effects on the cerebellum can be unified into one consolidated model in which failure of cell movement affects all major cerebellar neurons.
Influence of computer literacy and subject background on use of electronic resources by undergraduate students in universities in South-western Nigeria

The extent to which electronic resources are utilised by undergraduate students will depend largely on some factors pertaining to the users, especially computer literacy and subject background. Therefore, the study investigated the influence of computer literacy and subject background on the use of electronic resources by undergraduate students in two universities in South- western Nigeria. The survey research design was adopted in the study with the questionnaire as a major instrument for data collection. Simple random sampling and purposive sampling techniques were adopted to select three faculties and two departments each from the universities and 275 respondents out of 904 undergraduate students. Simple descriptive statistics was used to analyse the data. Results of the study revealed that 8(7.1%) of the respondents at the Federal University of Technology Akure (FUTA) and 30(19.0%) at the Obafemi Awolowo University Ile-Ife (OAU) visit the library to consult electronic resources. Although electronic resources in general are very important for academic tasks, 30(26.8%) of the respondents at FUTA and 32(20.3%) at OAU indicated that the Internet is most useful in discovering literature relevant to their subject background. Computer literacy and subject background influenced use of electronic information resources by the students. The study, therefore, recommended that measures should be taken to increase the level of computer literacy among the students for increased use of electronic resources available in the university libraries. Key words: Computer literacy, electronic resources, university libraries.