Miracle-dz/UniFAR-FTUs huggingface dataset:
Designing a GPS Receiver for the UNSW BlueSat Microsatellite

This paper describes a GPS-based navigation system designed for the University of New South Wales (UNSW) BLUEsat microsatellite. BLUEsat is a research-focussed low earth orbit microsatellite project designed and built entirely by students. Through the use of a modified, off-the-shelf GPS receiver, position, velocity and time data can be robustly provided in a highly dynamic environment. To allow a standard GPS receiver to function in space, many software and hardware modifications are necessary. Hardware and software interfaces have been carefully designed to allow integration within the BlueSat project. A Mitel GPS-chipset Software Development Kit (SDK) was available. The SDK consists of all source code that “drives” a GPS receiver, permitting all operations of the GPS receiver to be examined and, if necessary, permitting new algorithms for signal acquisition, tracking and navigation solution to be developed and tested. A modified Canadian Marconi Corporation AllStar GPS boardset was used as the baseline receiver hardware. The AllStar is based on a twelve-channel GPS chipset, consisting primarily of the GP2015 RF frontend and the GP2021 correlator chip. A 40MHz ARM60 microprocessor provides overall control of the system. Three RS-232 ports are available – two for general input/output and one for debugging. This hardware had to be interfaced to the main BlueSat computer. Techniques have been developed for processing the data and providing the system with navigation criteria. Risk mitigation is also examined. Limited testing has been performed, with the high velocity receiver able to robustly track GPS signals. The system’s firmware is currently being ported to a new generation hardware platform provided by the Australian company Signav Pty Ltd (SIGNAV, 2003). Further testing will be carried out when a multi-channel GPS constellation simulator becomes available.
Ball convex bodies in Minkowski spaces

The notion of ball convexity, considered in finite dimensional real Banach spaces, is a natural and useful extension of usual convexity; one replaces intersections of half-spaces by suitable intersections of balls. A subset $S$ of a normed space is called ball convex if it coincides with its ball hull, which is obtained as intersection of all balls (of fixed radius) containing $S$. Ball convex sets are closely related to notions like ball polytopes, complete sets, bodies of constant width, and spindle convexity. We will study geometric properties of ball convex bodies in normed spaces, for example deriving separation theorems, characterizations of strictly convex norms, and an application to complete sets. Our main results refer to minimal representations of ball convex bodies in terms of their ball exposed faces, to representations of ball hulls of sets via unions of ball hulls of finite subsets, and to ball convexity of increasing unions of ball convex bodies.
First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2,251 patients.

BACKGROUND First-line bevacizumab combined with chemotherapy significantly improves efficacy versus chemotherapy alone in human epidermal growth factor receptor 2 (HER2)-negative locally recurrent or metastatic breast cancer (LR/mBC). This large, open-label study further assesses first-line bevacizumab with taxane-based chemotherapy in routine oncology practice. PATIENTS AND METHODS Patients with HER2-negative LR/mBC, Eastern Cooperative Oncology Group (ECOG) performance status (PS) of zero to two and no prior chemotherapy for LR/mBC received bevacizumab 10 mg/kg every 2 weeks or 15 mg/kg every 3 weeks plus taxane-based chemotherapy (or other non-anthracycline chemotherapy) until disease progression, unacceptable toxicity or patient withdrawal. The primary end point was safety; time to progression (TtP) was a secondary end point. RESULTS Median follow-up in 2251 treated patients was 12.7 months. Median age was 53 years and 94% of patients had ECOG PS of zero or one. Bevacizumab was most commonly administered with single-agent paclitaxel (35%), single-agent docetaxel (33%) or taxane-based combination therapy (10%). The most frequent grade ≥3 adverse event (AE) was neutropenia (5.4%). Grade ≥3 AEs previously associated with bevacizumab included hypertension (4.4%), arterial/venous thromboembolism (3.2%), proteinuria (1.7%) and bleeding (1.4%). No new bevacizumab safety signals were observed. Median TtP was 9.5 months (95% confidence interval 9.1-9.9). CONCLUSIONS The study population in ATHENA was more representative of general oncology practice than populations enrolled into randomised trials, although there may have been some bias towards younger, fitter patients. The safety and efficacy of bevacizumab-taxane therapy in this large study were consistent with results from randomised first-line trials.
A COMPARISON BETWEEN HYBRID APPROACHES OF ANN AND ARIMA FOR INDIAN STOCK TREND FORECASTING

In this paper an attempt is made to develop hybrid models of three layer feed forward back propagation artificial neural network (ANN) and autoregressive integrated moving average (ARIMA) for forecasting the future index value and trend of Indian stock market viz. SENSEX, BSE IT, BSE Oil & Gas, BSE 100 and S& P CNX Nifty. Simulations have been done using prices of daily open, high, low and close of SENSEX, BSE IT, BSE Oil & Gas, BSE 100 and S& P CNX Nifty. These are chosen as input data values and output is the forecasted closing price of SENSEX, BSE IT, BSE Oil & Gas, BSE 100 and S& P CNX Nifty for the next day and future trend. Simulation results of hybrid models are compared with results of ANN based models and ARIMA based models. Convergence and performance of models have been evaluated on the basis of the simulation results done on MATLAB®6.1 and SPSS®13.0.
Children’s, Adult’s and Family's Emotional Stress in Context of Genomic Instability

Scientific data concerning the impact of emotional stress to human genomic instability very seldom describes in literature. For many scientists this connection is not supposed to be obvious, although oncologists and psychologists know that a prolonged state of heightened emotional tension is fraught with serious problems for the nervous-immune-endocrine system of the or-ganism. Moreover, oncologists know that cancer is often the result of resentment and loneliness. At the same time, the role of genome instability in processes of tumor induction and progression is proved very correctly. In the report will be paying attention to 3 aspects of human life in context of emotional stress expression and its connection with genomic instability: envi-ronmental pollution, genomic predisposes, ethic and social-economic problems. The report will contain data from literature and results of own research directed to the analyzing the impact of the degree of emotional stress expression on the children’s and adults’ genomic instability. Special attention will be paid to the investigation how emotional state of parents and teachers im-pact on young children’s genomic instability. Methods. For evaluation of stress expression levels we used the complex of standard psychological tests: questionnaires— for adults and 8-coloured M. Luscher’s test—for children. Estimation of genomic instability was carried out in blood cultures by test on chromosome aberration and micronuclei test with Cytochalasin B. Alteration of biochemical indices were detected by standard methods.
Using Dynamic Audio Feedback to Support Peripersonal Reaching in Young Visually Impaired People

Blind children engage with their immediate environment much less than sighted children, particularly through self-initiated movement or exploration. Research has suggested that providing dynamic feedback about the environment and the child's actions within/against it may help to encourage reaching activity and support spatial cognitive learning. This paper investigated whether the accuracy of peripersonal reaching (space within arm's reach) can be improved by the use of dynamic sound from both the objects to reach for and the reaching hand itself (via a worn speaker). We ran two studies that tested the efficacy of static and dynamic audio feedback designs with blind and visually impaired young people, to identify optimal feedback designs. Study 1 was with young adults aged 18 to 22 and Study 2 involved children aged 12 to 17. The results showed that dynamic audio feedback helps to build spatial connections between the objects and the reaching hand and participants were able to reach more accurately, compared to unchanging feedback.
Packet loss in a bufferless optical WDM switch employing shared tunable wavelength converters

We propose an architecture for a bufferless packet optical switch employing the wavelength dimension for contention resolution. The optical packet switch is equipped with tunable wavelength converters shared among the input lines. An analytical model Is proposed in order to determine the number of converters needed to satisfy prefixed packet loss probability constraints. This analytical model very accurately fits with simulations results. A sensitivity analysis of the required number of converters as a function of the main system parameters (number of input and output lines, number of wavelengths, .) and traffic parameters has been carried out. Making use of the introduced dimensioning procedure we have observed that the proposed architecture allows a saving in terms of employed number of converters with respect to the other architectures proposed in literature. Such a saving can reach about 95% of the number of converters.
Active, Reactive, and Proactive Approaches to Corporate Volunteering in Three Countries

This article explores discursive constructions of corporate volunteering (CV) across three countries. Based on the analysis of 29 qualitative interviews with employees working in small and medium size companies in Denmark, Slovenia, and the United States, we explore distinct discursive features of the embedded nature of CV in the broader context of corporate social responsibility (CSR). The findings reveal that different orientations to CSR inform and shape the ways participants working in the three countries construct CV as active, reactive, or proactive corporate practice. This study aids in understanding of the cross-cultural distinctiveness of discourses that pertain to CV from an employee perspective, while also challenging the common notion of CV as an aspect of strategic CSR.
#quitbullyingme: Teachers’ and Speech-Language Pathologists’ Perceptions of the Academic, Social, and Emotional Impact of Cyberbullying on Individuals Who Stutter

The purpose of this study was to examine Teachers’ and Speech-Language Pathologists’ perceptions on the academic, social, and emotional impact that cyberbullying has on individuals who stutter. This study also looked at Teachers’ and Speech-Language Pathologists’ management skills of cyberbullying when cyberbullying arose with their students or clients. The researcher created a survey which included Likert-type questions and open response questions to address these topics. As concluded from the results of this study, Teachers and Speech-Language Pathologists both believe that students and clients who stutter are impacted the most emotionally, directly associating with cyberbullying. In addition to this, the results showed that Teachers and Speech-Language Pathologists were not as comfortable with managing bullying and cyberbullying when it has occurred. One major implication of this study is that Teachers and Speech-Language Pathologists should be provided training programs and bullying prevention models that specifically address cyberbullying. By including cyberbullying into these prevention models, it would increase the feelings of preparedness that these professionals feel when addressing any acts of bullying and/or cyberbullying.
Are story retelling and story generation connected to reading skills? Evidence from Finnish

This three-year follow-up study investigated the associations of narrative and reading skills in typically developing Finnish children. Twenty children performed narrative retelling and story generation tasks twice, at five and eight years of age. Reading comprehension and word recognition tests were performed at the age of eight. Narratives were analysed for relevant information, total number of word tokens, clausal density and evaluation. The results showed increased narrative abilities with age, but the development was not seen in all narrative variables. This suggests that narrative tasks might capture development somewhat differently. Both narrative tasks were connected to reading skills. However, while retelling was connected to reading comprehension only, story generation related to both reading comprehension and word recognition. This study extends prior research by showing that not only retelling but also story generation is associated with reading.
Anti-CD4-mediated selection of Treg in vitro – in vitro suppression does not predict in vivo capacity to prevent graft rejection

Regulatory T cells (Treg) have been shown to play a role in the prevention of autoimmune diseases and transplant rejection. Based on an established protocol known to generate alloantigen reactive Treg in vivo, we have developed a strategy for the in vitro selection of Treg. Stimulation of unfractionated CD4+ T cells from naive CBA.Ca (H2k) mice with C57BL/10 (H2b) splenocytes in the presence of an anti‐CD4 antibody, YTS 177, resulted in the selection of Treg able to inhibit proliferation of naive T cells. In vivo, the cells were able to prevent rejection of 80% C57BL/10 skin grafts when co‐transferred to CBA.Rag–/– mice together with naive CD45RBhighCD4+ cells. Purification of CD62L+CD25+CD4+ cells from the cultures enriched for cells with regulatory activity; as now 100% survival of C57BL/10 skin grafts was achieved. Furthermore, differentiation of Treg could be also achieved when using purified CD25–CD4+ naive T cells as a starting population. Interestingly, further in vitro expansion resulted in a partial loss of CD4+ cells expressing both CD62L and CD25 and abrogation of their regulatory activity in vivo. This study shows that alloantigen stimulation in the presence of anti‐CD4 in vitro provides a simple and effective strategy to generate alloreactive Treg.
ST93-Queensland community-acquired meticillin-resistant Staphylococcus aureus clone in France: outbreak in a scout camp and sporadic cases, July to August 2012.

We describe the occurrence in France of a Panton-Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) ST93 clone, a predominant community-acquired (CA)-MRSA in Australia. In July to August 2012, an outbreak in a scout camp (n=3) and sporadic cases (n=2) of skin and soft tissue infections were reported. Investigations suggested importation of the clone through travel and onward transmission. This illustrates the epidemic potential of this lineage and the role of travellers in the spread of PVL-positive CA-MRSA.
Observations of L1521F: A highly evolved starless core

We observed the pre-stellar core L1521F in dust emission at 1.2 mm and in two transitions each of N2H + ,N 2D + ,C 18 O and C 17 O in order to increase the sample of well studied centrally concentrated and chemically evolved starless cores, likely on the verge of star formation, and to determine the initial conditions for low-mass star formation in the Taurus Molecular Cloud. The dust observation allows us to infer the density structure of the core and together with measurements of CO isotopomers gives us the CO depletion. N2H + and N2D + lines are good tracers of the dust continuum and thus they give kinematic information on the core nucleus. We derived in this object a molecular hydrogen number density n(H2) ∼ 10 6 cm −3 and a CO depletion factor, integrated along the line of sight, fD ≡ 9.5 × 10 −5 /xobs(CO) ∼ 15 in the central 20 �� , similar to the pre-stellar core L1544. However, the N(N2D + )/N(N2H + ) column density ratio is ∼0.1, a factor of about 2 lower than that found in L1544. The observed relation between the deuterium fractionation and the integrated CO depletion factor across the core can be reproduced by chemical models if N2H + is slightly (factor of ∼2 in fractional abundance) depleted in the central 3000 AU. The N2H + and N2D + linewidths in the core center are ∼0.3 km s −1 , significantly larger than in other more quiescent Taurus starless cores but similar to those observed in the center of L1544. The kinematical behaviour of L1521F is more complex than seen in L1544, and a model of contraction due to ambipolar diffusion is only marginally consistent with the present data. Other velocity fields, perhaps produced by accretion of the surrounding material onto the core and/or unresolved substructure, are present. Both chemical and kinematical analyses suggest that L1521F is less evolved than L1544, but, in analogy with L1544, it is approaching the "critical" state.
Two-folded implementation of a 12-pulse TCR with dissimilar transformers for a ladle furnace: reactive power compensation and power system redundancy

This paper is devoted to the design and implementation of a 12-pulse thyristor controlled reactor (TCR) system, which constitutes a low-cost solution to the reactive power compensation problem of a ladle furnace in Iskenderun iron and steel plant (ISDEMIR). Design objectives and elimination of 5th and 7th harmonic current components produced by 6-pulse TCRs are met by connecting two sets of 6 kV, 6 MVAr TCRs to the 34.5 kV ladle furnace bus by the use of two separate converter transformers with delta- and wye-connected secondaries. The effects of dissimilarities between the two sets of 6-pulse TCRs on the harmonic current content of the resulting 12-pulse TCR system are also presented in this paper. Both reactive power compensation and power system redundancy objectives are met by using two separate and dissimilar transformers instead of a single transformer with identical /spl Delta/-and Y-connected secondaries for connection to 6-pulse TCRs, resulting in a two-folded design. One of these transformers is chosen as a sufficiently large unit with two identical /spl Delta/-connected secondaries to supply the ladle furnace in emergency or during maintenance periods of main transformer. In normal operation mode of the resulting ladle furnace power system, the 12-pulse TCR implemented in the project gives quite satisfactory results in reactive power compensation and nearly meets harmonic standards currently used in the country.
Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants

Background. Mucosal or oral tolerance, an established method for inducing low-risk antigen-specific hyporesponsiveness, has not been investigated in vascularized composite allograft (VCA) research. We studied its effects on recipient immune responses and VCA rejection. Methods. Lewis rats (n = 12; TREATED) received seven daily intrajejunal treatments of 5 × 107 splenocytes from semiallogeneic Lewis-Brown-Norway rats (LBN) or vehicle (n = 11; SHAM). Recipients' immune responses were assessed by mixed lymphocyte reaction (MLR) against donor antigen and controls. Other Lewis (n = 8; TREATED/VCA) received LBN hindlimb VCA and daily intrajejunal treatments of 5 × 107 LBN splenocytes, or LBN VCA without treatment (n = 5; SHAM/VCA), until VCAs rejected. Recipients' immune responses were characterised and VCAs biopsied for histopathology. Immunosuppressants were not used. Results. LBN-specific hyporesponsiveness was induced only in treated Lewis recipients. Treatment significantly reduced MLR alloreactivity, significantly reduced VCA rejection on histopathology, and significantly delayed clinical VCA rejection (P < 0.0005; TREATED/VCA mean 9.6 versus 6.0 days for SHAM/VCA). Treatment significantly increased immunosuppressive IL-10/IL-4/TGF-β production and significantly decreased proinflammatory IFN-γ/TNF-α. Conclusion. Jejunal exposure to antigen conferred donor specific hyporesponsiveness that delayed VCA rejection. This method may offer a low-risk adjunctive treatment option to help protect VCAs from rejection.
IS EVALUATIVE CONDITIONING A QUALITATIVELY DISTINCT FORM OF CLASSICAL CONDITIONING ?

This paper contains a critical review of the claim that evaluative conditioning (EC) represents a theoretically distinct form of classical conditioning. A review of the evidence suggests that: (i) while it is claimed that EC can occur without awareness, EC studies have either adopted inappropriate statistical comparisons to demonstrate this or have failed to use the control conditions necessary to indicate that what is being measured is associative conditioning; (ii) there is no theoretical reason why conditioning without awareness might be observed in any conditioning paradigm if a relatively complex cova~ation assessment procedure such as that adopted in EC studies is used; and (iii) there are a variety of possible explanations for the relative resistance to extinction reported with EC, some of which allude to failure to use appropriate control conditions and others which point to specific details unique to the EC extinction procedure. Until these appropriate procedural and statistical comparisons are made, it is concluded that it is premature to assume that EC represents a form of~onditioning that is theoretically distinct from other types of classical conditioning.
Performance Evaluation of Manual and Automated (MagNA Pure) Nucleic Acid Isolation in HPV Detection and Genotyping Using Roche Linear Array HPV Test

Nucleic acids of human papillomavirus (HPV) isolated by manual extraction method (AmpliLute) and automated MagNA pure system were compared and evaluated with cytohistological findings in 253 women. The concordance level between AmpliLute and MagNA was very good 93.3% (κ = 0.864, P < .0001). Overall HPVpositivity detected by AmpliLute was 57.3% (30.4% as single and 27% as multiple infections) in contrast to MagNA 54.5% (32% and 23%, resp.). Discrepant results observed in 25 cases: 11 MagNA(−)/AmpliLute(+), 10 of which had positive histology; 5 MagNA(+)/AmpliLute(−) with negative histology; 8 MagNA(+)/AmpliLute(+): in 7 of which AmpliLute detected extra HPV genotypes and 1 MagNA(invalid)/AmpliLute(+) with positive histology. Both methods performed well when compared against cytological (area under curve (AUC) of AmpliLute 0.712 versus 0.672 of MagNA) and histological diagnoses (AUC of AmpliLute 0.935 versus 0.877 of MagNA), with AmpliLute showing a slightly predominance over MagNA. However, higher sensitivities, specificities, and positive/negative predictive values were obtained by AmpliLute.