Miracle-dz/UniFAR-FTUs huggingface dataset:
On the signatures of gravitational redshift : the onset of relativistic emission lines

Aims. We quantify the effect of gravitational redshift on emission lines to explore the transition region from the Newtonian to the Einsteinian regime. With the emitting region closer to the Kerr black hole, lines are successively subjected to a stronger gravitationally induced shift and distortion. Simulated lines are compared to broad, optical emission lines observed in Mrk 110. Methods. We simulate relativistic emission line profiles by using Kerr ray tracing techniques. Emitting regions are assumed to be thin equatorial rings in stationary Keplerian rotation. The emission lines are characterised by a generalized Doppler factor or redshift associated with the line core. Results. With decreasing distance from the black hole, the gravitational redshift starts to smoothly deviate from the Newtonian Doppler factor: shifts of the line cores reveal an effect at levels of 0.0015 to 60% at gravitational radii ranging from 10 5 to 2. This corresponds to fully relativistic Doppler factors of 0.999985 to 0.4048. The intrinsic line shape distortion by strong gravity i.e. very asymmetric lines occur at radii smaller than roughly ten gravitational radii. Conclusions. Due to the asymptotical flatness of black hole space-time, GR effects are ubiquitous and their onset can be tested observationally with sufficient spectral resolution. With a resolving power of ∼100 000, yielding a resolution of ≈0.1 A for optical and near-infrared broad emission lines like Hβ ,H eII and Paα, the gravitational redshift can be probed out to approximately 75 000 gravitational radii. In general, gravitational redshift is an important indicator of black hole mass and disk inclination as recently demonstrated by observations of optical lines in Mrk 110. Comparing our simulated lines with this observations, we independently confirm an inclination angle of 30 degrees for the accretion disk. Redshift deviations induced by black hole spin can be probed only very close to the black hole e.g. with X-ray iron lines.
A Probabilistic Parser as a Model of Global Processing Difficulty

We present a model of global processing difficulty in human parsing. This model is based on a probabilistic context-free grammar and is trained on a realistic corpus sample. It achieves broad coverage and good parsing accuracy on unseen text, and its predictions are significantly correlated with experimental data on word order preferences in German. The model makes predictions about the differential behavior of verb final and verb initial sentences and provides evidence for the importance of lexical information in sentence processing.
Voluntary inhibition of reflex: Effects of consistent meditative practice

The present study investigated the effects of meditative practices on the regulation of autonomic function. 74 subjects (38 women; 36 men) comprised from a range of experienced and nonexperienced meditators, engaged in a series of psychophysiological tasks designed to generate specific autonomic states. Regression analyses revealed that experienced meditators, as predicted, displayed greater suppression of myocardial reactivity during a highly reflexive and stressful task. Meditative practice also predicted a rise in electrodermal activity during a relaxation task, contrary to expectations. These results support the concept that meditative practices may alter aspects of autonomic function. Further, these results inform an emerging mind-body paradigm and illustrate the potential consequences of meditative practices in specific disease states and prevention.
Author ' s personal copy Modified material constitutive models for serrated chip formation simulations and experimental validation in machining of titanium alloy Ti – 6 Al – 4

Titanium alloys present superior properties such as high strength-to-weight ratio and resistance to corrosion but, possess poor machinability. In this study, influence of material constitutive models and elastic–viscoplastic finite element formulation on serrated chip formation for modeling of machining Ti–6Al–4V titanium alloy is investigated. Temperature-dependent flow softening based modified material models are proposed where flow softening phenomenon, strain hardening and thermal softening effects and their interactions are coupled. Orthogonal cutting experiments have been conducted with uncoated carbide (WC/Co) and TiAlN coated carbide cutting tools. Temperaturedependent flow softening parameters are validated on a set of experimental data by using measured cutting forces and chip morphology. Finite Element simulations are validated with experimental results at two different rake angles, three different undeformed chip thickness values and two different cutting speeds. The results reveal that material flow stress and finite element formulation greatly affects not only chip formation mechanism but also forces and temperatures predicted. Chip formation process for adiabatic shearing in machining Ti–6Al–4V alloy is successfully simulated using finite element models without implementing damage models. & 2010 Elsevier Ltd. All rights reserved.
The Impact of Organizational Memory on New Product Performance and Creativity

Arguing that organizational memory affects key new product development processes by influencing the (1) interpretation of incoming information and (2) the performance of new product action routines, the authors introduce four dimensions of organizational memory, including the amount and dispersion of memory. Data from 92 new product development projects indicate that higher organizational memory levels enhance the short-term financial performance of new products, whereas greater memory dispersion increases both the performance and creativity of new products. They also find, however, that under some conditions of high environmental turbulence, high memory dispersion actually detracts from creativity and has no effect on financial performance. Under conditions of low turbulence, high memory dispersion promotes higher levels of creativity and short-term financial performance. These findings provide some initial evidence that knowledge is not an unconditionally positive asset and suggest that developing and sustaining valuable organizational memory may require attention not only to the appropriate levels of memory but also to managing subtle aspects of memory dispersion and deployment. These results imply that if organizations fail to understand the subtle ways in which different features of organizational memory influence product development, they may fail to harvest the full value of organizational learning.
The Final Maturation of at Least Some Single-Positive Cd4hiThymocytes Does Not Require T Cell Receptor–Major Histocompatibility Complex Contact

The majority (∼70%) of postselection CD4+ single-positive (SP) thymocytes are CD8loCD4hi. These cells express very low levels of CD8, undetectable by flow cytofluorimetric (FCM) analysis, but sufficiently high to allow purification by panning. Unlike the fully mature CD8−CD4hi thymocytes, which account for the remaining ∼30% of the SP CD4+ thymocytes, CD8loCD4hi cells are functionally immature and short-lived unless they receive an unidentified maturation signal from the thymus. In this study, we tested the hypothesis that this signal is provided by a T cell receptor (TCR)–major histocompatibility complex (MHC) class II interaction. Using intrathymic transfer, we show that the immature CD8loCD4hi cells could complete their intrathymic maturation and populate the peripheral lymphoid organs in the absence of MHC class II (and class I) molecules. Furthermore, in mice devoid of class II (and class I) molecules, the progeny of CD8loCD4hi cells was long-lived and functionally reactive to allogeneic class II molecules, although their numbers in the spleen and the mesenteric lymph node were ∼40–50% lower than those in class II+ mice 5 mo after transfer. Control experiments demonstrated that the surviving cells did not originate from the contaminating mature thymocytes. These results demonstrate that the final maturation, proliferation, and peripheral survival (up to 5 mo) of at least some postselection CD4+ SP cells do not require the TCR–MHC class II interaction. They also indicate that the TCR–MHC class II interaction(s) required for the intrathymic development of long-lived CD4+ SP cells occurs before the CD4hi SP stage of development.
Beyond reward prediction errors: the role of dopamine in movement kinematics

We recorded activity of dopamine (DA) neurons in the substantia nigra pars compacta in unrestrained mice while monitoring their movements with video tracking. Our approach allows an unbiased examination of the continuous relationship between single unit activity and behavior. Although DA neurons show characteristic burst firing following cue or reward presentation, as previously reported, their activity can be explained by the representation of actual movement kinematics. Unlike neighboring pars reticulata GABAergic output neurons, which can represent vector components of position, DA neurons represent vector components of velocity or acceleration. We found neurons related to movements in four directions—up, down, left, right. For horizontal movements, there is significant lateralization of neurons: the left nigra contains more rightward neurons, whereas the right nigra contains more leftward neurons. The relationship between DA activity and movement kinematics was found on both appetitive trials using sucrose and aversive trials using air puff, showing that these neurons belong to a velocity control circuit that can be used for any number of purposes, whether to seek reward or to avoid harm. In support of this conclusion, mimicry of the phasic activation of DA neurons with selective optogenetic stimulation could also generate movements. Contrary to the popular hypothesis that DA neurons encode reward prediction errors, our results suggest that nigrostriatal DA plays an essential role in controlling the kinematics of voluntary movements. We hypothesize that DA signaling implements gain adjustment for adaptive transition control, and describe a new model of the basal ganglia (BG) in which DA functions to adjust the gain of the transition controller. This model has significant implications for our understanding of movement disorders implicating DA and the BG.
Comparison between decision-level and feature-level fusion of acoustic and linguistic features for spontaneous emotion recognition

Detection of affective states in speech could improve the way users interact with electronic devices. However the analysis of speech at the acoustic level could be not enough to determine the emotion of a user speaking in a realistic scenario. In this paper we analysed the spontaneous speech recordings of the FAU Aibo Corpus at the acoustic and linguistic levels to extract two sets of acoustic and linguistic features. The acoustic set was reduced by a greedy procedure selecting the most relevant features to optimize the learning stage. We experimented with three classification approaches: Naïve-Bayes, a support vector machine and a logistic model tree, and two fusion schemes: decision-level fusion, merging the hard-decisions of the acoustic and linguistic classifiers by means of a decision tree; and feature-level fusion, concatenating both sets of features before the learning stage. Despite the low performance achieved by the linguistic data, a dramatic improvement was achieved after its combination with the acoustic information, improving the results achieved by this second modality on its own. The results achieved by the classifiers using the parameters merged at feature level outperformed the classification results of the decision-level fusion scheme, despite the simplicity of the scheme.
Analysis of endometrial thickness measured by transvaginal ultrasonography in obese patients

ABSTRACT Objective To compare the endometrial echo values obtained by transvaginal ultrasonography with the body mass index of postmenopausal patients; to verify if there is higher prevalence of endometrial thickening in women with body mass index ≥30. Methods This is an analytical and cross-sectional study that evaluated 294 patients. Postmenopausal women were included, and those on hormone therapy were excluded. The variables evaluated were body mass index (considering obesity if >30), number of pregnancies, years since menopause, and age. These variables were correlated with endometrial echography. Results There was a statistically significant correlation between overweight and obese patients and increased endometrial thickness (p=0.0236). The correlation between age and endometrial echo was negative and statistically significant, that is, the older the woman, the lower the endometrial thickness (p=0.0478). Pregnancies and years since menopause showed no statistical significance in relation to endometrial echo, with p=0.0614 and p=0.115, respectively. Conclusion There was positive and significant correlation between body mass index ≥30 and endometrial thickeness.
Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome

Although the role of CD4+ T cells and in particular Tregs and Th17 cells is established in myelodysplastic syndrome(MDS), the contribution of other components of immune system is yet to be elucidated fully. In this study we investigated the number and function of myeloid derived suppressor cells (MDSCs) in fresh peripheral blood and matched bone marrow samples from 42 MDS patients and the potential correlation with risk of disease progression to acute myeloid leukemia (AML). In peripheral blood, very low-/low risk patients had significantly lower median MDSC number (0.16×109/L(0.03–0.40)) compared to intermediate-/high-/very high risk patients, in whom median MDSC counts was 0.52×109/L(0.10–1.78), p < 0.005. When co-cultured with CD4+ effector T-cells (T-effectors), MDSCs suppress Teffector proliferation in both allogeneic and autologous settings. There was a positive correlation between the number of Tregs and MDSCs (Spearman R = 0.825, p < 0.005) in high risk and not low risk patients. We also investigated MDSCs' expression of bone marrow-homing chemokine receptors, and our data shows that MDSCs from MDS patients express both CXCR4 and CX3CR1 which might facilitate migration of MDSCs to bone marrow. Monocytic MDSCs(M-MDSCs) which are more frequent in the peripheral blood express higher levels of CX3CR1 and CXCR4 than the granulocytic subtype (G-MDSCs), and circulating M-MDSCs had significantly higher CX3CR1 expression compared to bone-marrow M-MDSCs in intermediate-/high-/very high risk MDS. Our results suggest that MDSCs contribute significantly to the dysregulation of immune surveillance in MDS, which is different between low and high risk disease. It further points at mechanisms of MDSCs recruitment and contribution to the bone marrow microenvironment.
Cardiovascular Risks Associated with Low Dose Ionizing Particle Radiation

Previous epidemiologic data demonstrate that cardiovascular (CV) morbidity and mortality may occur decades after ionizing radiation exposure. With increased use of proton and carbon ion radiotherapy and concerns about space radiation exposures to astronauts on future long-duration exploration-type missions, the long-term effects and risks of low-dose charged particle irradiation on the CV system must be better appreciated. Here we report on the long-term effects of whole-body proton (1H; 0.5 Gy, 1 GeV) and iron ion (56Fe; 0.15 Gy, 1GeV/nucleon) irradiation with and without an acute myocardial ischemia (AMI) event in mice. We show that cardiac function of proton-irradiated mice initially improves at 1 month but declines by 10 months post-irradiation. In AMI-induced mice, prior proton irradiation improved cardiac function restoration and enhanced cardiac remodeling. This was associated with increased pro-survival gene expression in cardiac tissues. In contrast, cardiac function was significantly declined in 56Fe ion-irradiated mice at 1 and 3 months but recovered at 10 months. In addition, 56Fe ion-irradiation led to poorer cardiac function and more adverse remodeling in AMI-induced mice, and was associated with decreased angiogenesis and pro-survival factors in cardiac tissues at any time point examined up to 10 months. This is the first study reporting CV effects following low dose proton and iron ion irradiation during normal aging and post-AMI. Understanding the biological effects of charged particle radiation qualities on the CV system is necessary both for the mitigation of space exploration CV risks and for understanding of long-term CV effects following charged particle radiotherapy.
RESPONSE TIME VARIABILITY SIGNATURES OF NOVEL WORD LEARNING

Abstract Response time variability and its changes over time have been interpreted as indicative of levels of knowledge automatization. Predominantly, only declines in variability have been examined over the course of practice and growing second language proficiency. We discuss possible scenarios that may involve increasing, rather than declining variability, such as the establishment of new memory representations. We present repeated-measures lexical decision data on novel words encountered incidentally in a lexical decision task, which show increased variability as familiarity increases. Similar patterns were observed in our reanalyses of data from other novel word learning experiments with task demands different from ours: auditory presentation and a posttest after seven days (Brown & Gaskell, 2014), as well as picture-matching and production tests (Bartolotti & Marian, 2014). Jointly, these results suggest that when no prior representation of a word exists, increased variability may index learning during its initial stages.
Investigating Race-of-Interviewer Effects in the Contemporary South

In this paper, we expand the existing research on interviewer effects in telephone surveys by investigating the interacting effects of interviewers’ race and gender on responses to a survey of African-American southerners conducted in February 2009 by Winthrop University and South Carolina Educational Television (ETV) on questions regarding topics such as * The survey on which this paper was based was conducted with the financial support of South Carolina Educational Television and the College of Arts and Sciences, Winthrop University; their generosity is greatly appreciated by the authors. We also thank Adolphus Belk, Jr. for his contributions to the design of the survey. Any errors in analysis or interpretation are the sole responsibility of the authors.
Benefits of a Continuous Ambulatory Peritoneal Dialysis (CAPD) Technique with One Icodextrin-Containing and Two Biocompatible Glucose-Containing Dialysates for Preservation of Residual Renal Function and Biocompatibility in Incident CAPD Patients

In a prospective randomized controlled study, the efficacy and safety of a continuous ambulatory peritoneal dialysis (CAPD) technique has been evaluated using one icodextrin-containing and two glucose-containing dialysates a day. Eighty incident CAPD patients were randomized to two groups; GLU group continuously using four glucose-containing dialysates (n=39) and ICO group using one icodextrin-containing and two glucose-containing dialysates (n=41). Variables related to residual renal function (RRF), metabolic and fluid control, dialysis adequacy, and dialysate effluent cancer antigen 125 (CA125) and interleukin 6 (IL-6) levels were measured. The GLU group showed a significant decrease in mean renal urea and creatinine clearance (-Δ1.2±2.9 mL/min/1.73 m2, P=0.027) and urine volume (-Δ363.6±543.0 mL/day, P=0.001) during 12 months, but the ICO group did not (-Δ0.5±2.7 mL/min/1.73 m2, P=0.266; -Δ108.6±543.3 mL/day, P=0.246). Peritoneal glucose absorption and dialysate calorie load were significantly lower in the ICO group than the GLU group. The dialysate CA125 and IL-6 levels were significantly higher in the ICO group than the GLU group. Dialysis adequacy, β2-microglobulin clearance and blood pressure did not differ between the two groups. The CAPD technique using one icodextrin-containing and two glucose-containing dialysates tends to better preserve RRF and is more biocompatible, with similar dialysis adequacy compared to that using four glucose-containing dialysates in incident CAPD patients. [Clincal Trial Registry, ISRCTN23727549] Graphical Abstract
Extensive Management Promotes Plant and Microbial Nitrogen Retention in Temperate Grassland

Leaching losses of nitrogen (N) from soil and atmospheric N deposition have led to widespread changes in plant community and microbial community composition, but our knowledge of the factors that determine ecosystem N retention is limited. A common feature of extensively managed, species-rich grasslands is that they have fungal-dominated microbial communities, which might reduce soil N losses and increase ecosystem N retention, which is pivotal for pollution mitigation and sustainable food production. However, the mechanisms that underpin improved N retention in extensively managed, species-rich grasslands are unclear. We combined a landscape-scale field study and glasshouse experiment to test how grassland management affects plant and soil N retention. Specifically, we hypothesised that extensively managed, species-rich grasslands of high conservation value would have lower N loss and greater N retention than intensively managed, species-poor grasslands, and that this would be due to a greater immobilisation of N by a more fungal-dominated microbial community. In the field study, we found that extensively managed, species-rich grasslands had lower N leaching losses. Soil inorganic N availability decreased with increasing abundance of fungi relative to bacteria, although the best predictor of soil N leaching was the C/N ratio of aboveground plant biomass. In the associated glasshouse experiment we found that retention of added 15N was greater in extensively than in intensively managed grasslands, which was attributed to a combination of greater root uptake and microbial immobilisation of 15N in the former, and that microbial immobilisation increased with increasing biomass and abundance of fungi. These findings show that grassland management affects mechanisms of N retention in soil through changes in root and microbial uptake of N. Moreover, they support the notion that microbial communities might be the key to improved N retention through tightening linkages between plants and microbes and reducing N availability.
Do we have to agree? Accommodating unity in diversity in post-terror Norway

Fostering unity in diversity while ensuring spaces for disagreement is a key challenge for all liberal democracies with ethnic and religious diversity. Increasing polarization, not least due to the threat of terror attacks, exacerbates this challenge. Drawing on the case of Norway in the aftermath of the 2011 terror attacks motivated by ‘Eurabia’ sentiments, we find that both consensus and contestation are necessary to counter conflictual polarization. Consensus establishes a necessary common ground for interaction, while contestation permits diverging interpretations to emerge. Working with 21 semi-structured interviews with people in influential roles in Norway, we propose an analytical framework that draws on both political theory and empirically based analyses of interaction in diverse societies. We find that consensus-oriented approaches immediately following terror attacks can build unity and bridge divides across existing ethnic, religious, and political diversity. Over time, however, they may contribute to conflict, as they are perceived to conceal underlying disagreements. Perspectives founded on dualistic contestation can also cultivate conflict if opponents increasingly perceive each other as enemies in a hostile environment. A plurality of contestations, by contrast, can de-escalate conflict and thereby ease renewed cooperation. Thus, our findings point to the need for a perspective that transcends the dualism of “us” and “them”, and acknowledges the plurality of human beings in order to de-escalate the spiral of polarization.