Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH KEMAMPUAN MEMBACA ALQUR’AN TERHADAP HASIL BELAJAR MAHASISWA POLITEKNIK NEGERI MEDAN

ABSTRACT This article is the result of research to find information about student's ability and persistence to read Alqur'an and its effect on result of learning. The research method used is f test and t test and analyzed with simple linear regression statistic formula. This research was conducted on 46 students of Energy Conversion Technique State Polytechnic of Medan. Data collection techniques are observation, interview, questionnaire and oral and written test. Based on the statistical analysis concluded that the data show the hypothesis of researchers have been tested empirically that the ability to read Alqur'an has an influence on student learning outcomes. This is indicated by Fcount> F table (106.726> 4.06), so Ho is rejected and Ha accepted. Also indicated by the test tcount> ttable = (10.331> 2.01537). This means that there is a linear, positive and significant influence between the ability to read Alqur'an on student learning outcomes. Improved student learning outcomes are influenced by the ability to read Alqur'an 70.1%. The rest of the students' learning outcomes are influenced by factors that are not observed in this study that is equal to 29.9%. This finding becomes a great opportunity for the effort to improve student's learning achievement by way of guiding the ability of reading the official and sustainable Alqur'an. Concrete students need to be motivated to form groups (halaqah) Alqur'an on campus whose activities can be up to Polmed even by using media on line. For lecturers also have to give rewards for students who are diligent and have good reading ability, let alone he has a good recitations talent and has achievements in MTQN. Keywords: ability to read Alqur'an, learning outcomes, improvement of achievement
Differential Expression of Apoptosis Related Genes in Selected Strains of Aedes aegypti with Different Susceptibilities to Dengue Virus

Aedes aegypti is the principal vector of Dengue viruses worldwide. We identified field collected insects with differential susceptibility to Dengue-2 virus (DENv-2) and used isofemale selection to establish susceptible and refractory strains based on midgut infection barriers. Previous experiments had identified higher expression of apoptosis-related genes in the refractory strain. To identify potential molecular mechanisms associated with DENv susceptibility, we evaluated the differential expression of Caspase-16, Aedronc, Aedredd, Inhibitor of apoptosis (AeIAP1) and one member of the RNAi pathway, Argonaute-2 in the midguts and fat body tissues of the selected strains at specific times post blood feeding or infection with DENv-2. In the refractory strain there was significantly increased expression of caspases in midgut and fatbody tissues in the presence of DENv-2, compared to exposure to blood alone, and significantly higher caspase expression in the refractory strain compared with the susceptible strain at timepoints when DENv was establishing in these tissues. We used RNAi to knockdown gene expression; knockdown of AeIAP1 was lethal to the insects. In the refractory strain, knockdown of the pro-apoptotic gene Aedronc increased the susceptibility of refractory insects to DENv-2 from 53% to 78% suggesting a contributing role of this gene in the innate immune response of the refractory strain.
Monopolistic Competition , Managerial Compensation , and the Distribution of Firms in General Equilibrium

We develop a general equilibrium model to show how the distribution of rm qualities, moral hazard, and monopolistic competition in the product market interact to a¤ect the distributions of rm size and managerial compensation. We exploit the properties of the unique, stationary general equilibrium of the model to derive a number of novel implications for the relations between the rm size and managerial compensation distributions, and the e¤ects of rm and product market characteristics on these distributions. Our results highlight a novel general equilibrium channel through which rm and product market characteristics a¤ect managerial compensation and incentives. Di¤erent determinants of competition have contrasting e¤ects on the distributions of rms and managerial compensation. An increase in the entry cost or exit probability decreases expected managerial compensation and the average size of rms, but increases the number of active rms. An increase in the elasticity of product substitution, however, decreases expected compensation if rm size is below an endogenous threshold, but increases expected compensation if rm size is above the threshold. An increase in productivity risk raises expected managerial compensation and the number of active rms. In general equilibrium, aggregate shocks to the manager- rm match quality distribution and rmsproductivity levels a¤ect compensation and incentives. Expected managerial compensation and average rm size decrease with the productivity level, while the number of active rms increases. We use our theoretical results to develop ten robust empirically testable hypotheses that relate industry characteristics the entry cost, the exit probability, the elasticity of product substitution, the productivity risk, and the productivity level to managerial compensation and the number of rms in the industry. We show support for nine of the ten hypotheses in our empirical analysis. We thank Alex Edmans, Daniel Ferreira, and seminar participants at the 2010 European Finance Association Conference (Frankfurt, Germany) and the University of New South Wales (Sydney, Australia) for insightful comments and suggestions. We are very grateful for excellent research assistance from Chunwei Xian. The usual disclaimer applies.
Computer simulations of phospholipid - membrane thermodynamic fluctuations

This paper reports all-atom computer simulations of ﬁve phospholipid membranes, DMPC, DPPC, DMPG, DMPS, and DMPSH, with a focus on the thermal equilibrium ﬂuctuations of volume, energy, area, thickness, and order parameter. For the slow ﬂuctuations at constant temperature and pressure (deﬁned by averaging over 0.5 nanosecond) volume and energy exhibit strong correlation. These quantities on the other hand do not correlate signiﬁcantly with area, thickness, or order parameter. The correlations are mainly reported for the ﬂuid phase, but we also give results for the ordered (gel) phase of two membranes, showing a similar picture. The cause of the observed strong correlations is identiﬁed by splitting volume and energy into contributions from tails, heads, and water, showing that the slow volume-energy ﬂuctuations derive from the tail region’s van der Waals interactions and are thus analogous the similar strong correlations recently observed in computer simulations of the Lennard-Jones and other simple van der Waals type liquids. The strong correlations reported here conﬁrm an assumption of a recent theory for nerve signal propagation proposed by Heimburg and Jackson (2005).
Real science at the petascale

We describe computational science research that uses petascale resources to achieve scientific results at unprecedented scales and resolution. The applications span a wide range of domains, from investigation of fundamental problems in turbulence through computational materials science research to biomedical applications at the forefront of HIV/AIDS research and cerebrovascular haemodynamics. This work was mainly performed on the US TeraGrid ‘petascale’ resource, Ranger, at Texas Advanced Computing Center, in the first half of 2008 when it was the largest computing system in the world available for open scientific research. We have sought to use this petascale supercomputer optimally across application domains and scales, exploiting the excellent parallel scaling performance found on up to at least 32 768 cores for certain of our codes in the so-called ‘capability computing’ category as well as high-throughput intermediate-scale jobs for ensemble simulations in the 32–512 core range. Furthermore, this activity provides evidence that conventional parallel programming with MPI should be successful at the petascale in the short to medium term. We also report on the parallel performance of some of our codes on up to 65 636 cores on the IBM Blue Gene/P system at the Argonne Leadership Computing Facility, which has recently been named the fastest supercomputer in the world for open science.
FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model

Amyloid-β (Aβ)-containing extracellular plaques and hyperphosphorylated tau-loaded intracellular neurofibrillary tangles are neuropathological hallmarks of Alzheimer's disease (AD). Although Aβ exerts neuropathogenic activity through tau, the mechanistic link between Aβ and tau pathology remains unknown. Here, we showed that the FcγRIIb-SHIP2 axis is critical in Aβ1-42-induced tau pathology. Fcgr2b knockout or antagonistic FcγRIIb antibody inhibited Aβ1-42-induced tau hyperphosphorylation and rescued memory impairments in AD mouse models. FcγRIIb phosphorylation at Tyr273 was found in AD brains, in neuronal cells exposed to Aβ1-42, and recruited SHIP2 to form a protein complex. Consequently, treatment with Aβ1-42 increased PtdIns(3,4)P2 levels from PtdIns(3,4,5)P3 to mediate tau hyperphosphorylation. Further, we found that targeting SHIP2 expression by lentiviral siRNA in 3xTg-AD mice or pharmacological inhibition of SHIP2 potently rescued tau hyperphosphorylation and memory impairments. Thus, we concluded that the FcγRIIb-SHIP2 axis links Aβ neurotoxicity to tau pathology by dysregulating PtdIns(3,4)P2 metabolism, providing insight into therapeutic potential against AD. DOI: http://dx.doi. org/10.7554/eLife.18691. 001
Effort‐Reward Imbalance and Depression in Japanese Medical Residents

Effort‐Reward Imbalance and Depression in Japanese Medical Residents: Yumi Sakata, et al. Department of Occupational Mental Health, Graduate School of Medical Sciences, Kitasato University—The effort‐reward imbalance is an important psychosocial factor which is related to poor health among employees. However, there are few studies that have evaluated effort‐reward imbalance among medical residents. The present study was done to determine the association between psychosocial factors at work as defined by the effort‐reward imbalance model and depression among Japanese medical residents. We distributed a questionnaire to 227 medical residents at 16 teaching hospitals in Japan at the end of August 2005. We asked participants to answer questions which included demographic information, depressive symptoms, effort‐reward imbalance, overcommitment and social support. Depression was evaluated using the Japanese version of the Center for Epidemiologic Studies‐Depression (CES‐D) scale. The effort‐reward imbalance and overcommitment were assessed by the Effort‐Reward Imbalance (ERI) questionnaire which Siegrist developed. Social support was determined on a visual analog scale. Logistic regression analysis was performed to determine the associations between effort‐reward imbalance and depressive symptoms. Depressive symptoms were found in 35 (29.2%) 1st‐year residents and 21 (27.6%) 2nd‐year residents. The effort‐reward ratio >1 (OR, 8.83; 95% CI, 2.87–27.12) and low social support score (OR, 2.77, 95% CI, 1.36–5.64) were associated with depressive symptoms among medical residents. Effort‐reward imbalance was independently related to depression among Japanese medical residents. The present study suggests that balancing between effort and reward at work is important for medical residents' mental health.
The Brazilian Journal of INFECTIOUS DISEASES Japanese encephalitis: a review of the Indian perspective

Japanese encephalitis virus (JEV) causes Japanese encephalitis, which is a leading form of viral encephalitis in Asia, with around 50,000 cases and 10,000 deaths per year in children below 15 years of age. The JEV has shown a tendency to extend to other geographic regions. Case fatality averages 30% and a high percentage of the survivors are left with perma-nent neuropsychiatric sequelae. Currently, there is no cure for JEV, and treatment is mainly supportive. Patients are not infectious, but should avoid further mosquito bites. A number of antiviral agents have been investigated; however, none of these have convincingly been shown to improve the outcome of JEV. In this review, the current knowledge of the epidemiology and the pathogenesis of this deadly disease have been summarized.
The Effect of Preimplantation Genetic Screening on Implantation Rate in Women over 35 Years of Age

Objective Advanced maternal age (AMA) is an important factor in decreasing success of assisted reproductive technology by having a negative effect on the success rate of intra-cytoplasmic sperm injection (ICSI), particularly by increasing the rate of embryo aneuploidy. It has been suggested that the transfer of euploid embryos increases the implantation and pregnancy rates, and decreases the abortion rate. Preimplantation genetic screening (PGS) is a method for selection of euploid embryos. Past studies, however, have reported different results on the success of pregnancy after PGS in AMA. Investigating the pregnancy rate of ICSI with and without PGS in female partners over 35 years of age referred to infertility centers in Tehran. Materials and Methods In this randomized controlled trial, 150 couples with the female partner over age of 35 were included. Fifty couples underwent PGS and the remaining were used as the control group. PGS was carried out using fluorescent in situ hybridization (FISH) for chromosomes 13, 18, 21, X and Y. Results of embryo transfer following PGS were evaluated and compared with those in the control group. Results Implantation rates obtained in the PGS and control groups were 30 and 32% respectively and not significantly different (P>0.05). Conclusion PGS for chromosomes 13, 18, 21, X and Y does not increase implantation rate in women over 35 years of age and therefore the regular use of PGS in AMA is not recommended.
Increase in the Contents of Ginsenosides in Raw Ginseng Roots in Response to Exposure to 450 and 470 nm Light from Light-Emitting Diodes

An light-emitting diode (LED)-based light source was used as a monochromatic light source to determine the responses of raw ginseng roots (Panax ginseng Meyer) to specific emission spectra with respect to the production of ginsenosides. The ginsenoside content in the ginseng roots changed in response to the LED light treatments at 25℃ relative to the levels in the control roots that were treated in the dark or at 4℃ for 7 d. Ginseng roots were exposed to LEDs with four different peak emission wavelengths, 380, 450, 470, and 660 nm, in closed compartments. Compared with the control 4℃-treated roots, roots that were treated with 450 and 470 nm light showed a significantly increased production of ginsenosides (p<0.05), with increases of 64.9% and 74.1%, respectively. The contents of the ginsenosides Rb2, Rc, and Rg1 were significantly higher (p<0.05) in the 450 and 470 nm-treated root samples. The ratio of protopanaxadiol ginsenosides (Rb1, Rb2, Rc, and Rd) to protopanaxatriol ginsenosides (Rg1, Rg2, Re, and Rf) was significantly higher (p<0.05) in the 450 and 470 nm-treated root samples than in the control 4℃-treated roots. This is the first report that demonstrates the increase and conversion of ginsenosides in raw ginseng roots in response to exposure to LED light.
Editorial Manager(tm) for Journal of Labor Economics Manuscript Draft Title: Minimum Wages and Alcohol-related Traffic Fatalities among Teens Minimum Wages and Alcohol-related Traffic Fatalities among Teens

Using cross-state variation in minimum wages, we observe a positive relationship between the minimum wage and the number of alcohol-related accidents involving teen drivers. A similar effect is not observed when examining accidents among adults. The results are consistent with a high income elasticity for alcoholic beverages and driving activities among young people, in particular for consumption out of discretionary income accorded by higher minimum wages. Evidence of a sizeable impact of beer taxes on alcohol-related accidents among youths suggests that beer taxes are one avenue for policy makers to consider in counteracting this unintended consequence of minimum wages. Abstract Using cross-state variation in minimum wages, we observe a positive relationship between the minimum wage and the number of alcohol-related accidents involving teen drivers. A similar effect is not observed when examining accidents among adults. The results are consistent with a high income elasticity for alcoholic beverages and driving activities among young people, in particular for consumption out of discretionary income accorded by higher minimum wages. Evidence of a sizeable impact of beer taxes on alcohol-related accidents among youths suggests that beer taxes are one avenue for policy makers to consider in counteracting this unintended consequence of minimum wages. 1 " Giving money and power to government is like giving whiskey and car keys to teenage boys. " P.J. O'Rourke, Parliament of Whores
Warped-Slicer: Efficient Intra-SM Slicing through Dynamic Resource Partitioning for GPU Multiprogramming

As technology scales, GPUs are forecasted to incorporate an ever-increasing amount of computing resources to support thread-level parallelism. But even with the best effort, exposing massive thread-level parallelism from a single GPU kernel, particularly from general purpose applications, is going to be a difficult challenge. In some cases, even if there is sufficient thread-level parallelism in a kernel, there may not be enough available memory bandwidth to support such massive concurrent thread execution. Hence, GPU resources may be underutilized as more general purpose applications are ported to execute on GPUs. In this paper, we explore multiprogramming GPUs as a way to resolve the resource underutilization issue. There is a growing hardware support for multiprogramming on GPUs. Hyper-Q has been introduced in the Kepler architecture which enables multiple kernels to be invoked via tens of hardware queue streams. Spatial multitasking has been proposed to partition GPU resources across multiple kernels. But the partitioning is done at the coarse granularity of streaming multiprocessors (SMs) where each kernel is assigned to a subset of SMs. In this paper, we advocate for partitioning a single SM across multiple kernels, which we term as intra-SM slicing. We explore various intra-SM slicing strategies that slice resources within each SM to concurrently run multiple kernels on the SM. Our results show that there is not one intra-SM slicing strategy that derives the best performance for all application pairs. We propose Warped-Slicer, a dynamic intra-SM slicing strategy that uses an analytical method for calculating the SM resource partitioning across different kernels that maximizes performance. The model relies on a set of short online profile runs to determine how each kernel's performance varies as more thread blocks from each kernel are assigned to an SM. The model takes into account the interference effect of shared resource usage across multiple kernels. The model is also computationally efficient and can determine the resource partitioning quickly to enable dynamic decision making as new kernels enter the system. We demonstrate that the proposed Warped-Slicer approach improves performance by 23% over the baseline multiprogramming approach with minimal hardware overhead.
Coupling ecophysiological and 3D architectural models of Helianthus annuus L. to analyse and simulate development and vegetative growth fluctuating temperature and incident radiation

Sunflower plant leaf area is very variable, even without any abiotic stress. We propose a structural-functional approach to analyse and model the variability of plant leaf area evolution and of plant architecture in response to temperature and light intensity in Helianthus annuus L. Contrasted experimental situations covering various light treatments between 2 and 40 mol m-2 d-1, including greenhouse, canopy and isolated plants layouts, with or without plant and leaves shading were studied. Radiative balance was estimated with MIR-MUSC-RADBAL software on 3D numerical plants constructed by the AMAPsim2 software. This approach enables analysing the effect of absorbed radiation on plant development, plant architecture and leaves expansion. Stable relationships related to the amount of absorbed radiation per leaf area unit were established with changes in (i) plant development pattern and (ii) in relative expansion rate of leaves. Duration of expansion was lengthened but relative growth rate was decreased in response to a reduction of absorbed radiation. These relations were used to propose an integrated model of plant leaf area with temperature and absorbed radiation as input data. The model reproduced satisfactory variations of plant development pattern and of relative expansion rates of leaves. This approach shows the existence of an adaptative response to limit the effect of a reduction of absorbed radiation on plant leaf area. (Resume d'auteur)
Thrombotic microangiopathy and cytomegalovirus disease in patients infected with human immunodeficiency virus.

Thrombotic microangiopathy (TMA) can occur during the course of human immunodeficiency virus (HIV) infection. Clinical and pathological data for 29 patients with TMA and HIV infection were recorded. In a retrospective case-control study, we analyzed the link between opportunistic infections or drug therapies and TMA. Twenty-five patients (mean CD4+ cell count +/- SD, 71.9 +/- 18.3/mm3) had renal impairment, and four had neurological dysfunction. In one-half the cases, the disease was progressive with isolated fragmentation anemia appearing several months before the clinical symptoms. The diagnosis of TMA was confirmed by histological examination of kidney biopsy specimens (18 cases). Endothelial cytomegalovirus (CMV) inclusions were associated with TMA in nine of 18 cases, whereas histological examination did not detect CMV in any control specimens (P < .001). The case-control study demonstrated a link between TMA and clinical CMV infection (odds ratio, 3.9; 95% confidence interval, 1.1-14). We conclude that TMA is a late complication of HIV infection and can be associated with systemic CMV infection in this setting.
Tackling mild head injury in rugby: a comparison of the cognitive profiles of professional rugby and cricket players

The aim of this study was to investigate the effect of cumulative mild head injury on the cognitive functioning of professional rugby players. A comprehensive battery of neuropsychological tests was administered to 26 professional rugby players and to a comparison group of 21 professional cricket players. The group test results of the rugby, cricket, rugby forwards and rugby backline players were each compared with established normative data. Generally, the comparison of the rugby and cricket mean scores relative to the normative data did not reveal significant differences on tests known to be sensitive to the effects of mild head injury. However, the comparison of variability for each of the rugby and cricket playing groups relative to variability for the normative data, revealed a pattern of increased variability among the rugby players. This implies a bimodal distribution in which a significant number of rugby players were performing poorly across these tests whereas a significant proportion were not. This variability effect was accounted for by further mean score comparisons which revealed that, as a group, it was the forward players whose performances were disproportionately poor on tests sensitive to the effects of mild head injury. The implications of these results are developed theoretically within the context of brain reserve capacity theory and suggestions for future research are provided.