Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessing State Mental Contamination: Development and Preliminary Validation of the State Mental Contamination Scale

ABSTRACT This 2-part study described the development and preliminary validation of the State Mental Contamination Scale (SMCS), a multi-item self-report measure of state mental contamination. In Study 1, community adults (N = 211) in the United States were randomly assigned to a pathogen disgust, moral disgust, or neutral condition and then completed the SMCS. Study 1 results supported a 1-factor structure of the SMCS items. Scores on the SMCS items evidenced good internal consistency and strong interitem correlations. SMCS scores were significantly greater following the 2 disgust conditions relative to the neutral condition and a full range of SMCS scores were found in the disgust conditions. An independent sample of community adults (N = 121) from the United States participated in Study 2 to extend Study 1 results. Study 2 results indicated that SMCS scores were manipulated independently of trait mental contamination, more strongly related to convergent than a discriminant measure, and shared unique variance with a criterion measure after controlling for convergent measures. The future use of the SMCS is discussed.
Double Constrained NMF for Hyperspectral Unmixing

Given only the collected hyperspectral data, unmixing aims at obtaining the latent constituent materials and their corresponding fractional abundances. Recently, many nonnegative matrix factorization (NMF)-based algorithms have been developed to deal with this issue. Considering that the abundances of most materials may be sparse, the sparseness constraint is intuitively introduced into NMF. Although sparse NMF algorithms have achieved advanced performance in unmixing, the result is still susceptible to unstable decomposition and noise corruption. To reduce the aforementioned drawbacks, the structural information of the data is exploited to guide the unmixing. Since similar pixel spectra often imply similar substance constructions, clustering can explicitly characterize this similarity. Through maintaining the structural information during the unmixing, the resulting fractional abundances by the proposed algorithm can well coincide with the real distributions of constituent materials. Moreover, the additional clustering-based regularization term also lessens the interference of noise to some extent. The experimental results on synthetic and real hyperspectral data both illustrate the superiority of the proposed method compared with other state-of-the-art algorithms.
Time Trends in Smoking Onset by Sex and Race/Ethnicity Among Adolescents and Young Adults: Findings From the 2006–2013 National Survey on Drug Use and Health

Introduction During the 2000s the number of adolescents who became new smokers in the United States declined while the number of young adults who did so increased. However, we do not know among which demographic groups these changes occurred. Methods We analyzed data from the 2006 to 2013 National Survey of Drug Use and Health (n = 180 079). Multivariate linear regression models were used to assess annual trends in smoking onset and log-binomial regression models to assess changes over time in the risk of smoking onset among young adults (18- to 25-years-old) relative adolescents (12- to 17-years-old). Results From 2006 to 2013, the rate of onset among young adults (6.3%) was greater than among adolescents (1.9%). Time trends demonstrated that annual declines in smoking onset occurred among white young adult males and females. Rates of smoking onset increased among black and Hispanic young adult males with a lower rate of decline among black and Hispanic young adult females. There was a greater risk of smoking onset among young adults relative to adolescents that did not change over time. Conclusions Smoking onset is becoming more concentrated in the young adult than adolescent years. Despite this trend, there were annual declines in young adult smoking onset but not uniformly across racial/ethnic groups. More effective strategies to prevent young adult smoking onset may contribute to a further decline in adult smoking and a reduction in tobacco-related health disparities. Implications Smoking onset is becoming more concentrated in the young adult years across sex and racial/ethnic groups. The United States may be experiencing a period of increasing age of smoking onset and must develop tobacco control policies and practices informed by these changes.
Sluggish Cognitive Tempo in Adults: Psychometric Validation of the Adult Concentration Inventory

As interest in sluggish cognitive tempo (SCT) increases, a primary limitation for the field is the lack of a unified set of symptoms for assessing SCT. No existing SCT measure includes all items identified in a recent meta-analysis as optimal for distinguishing between SCT and attention-deficit/hyperactivity disorder (ADHD) inattention. This study evaluates a new self-report measure for assessing SCT in adulthood, the Adult Concentration Inventory (ACI), which was developed in response to the meta-analytic findings for assessing SCT. Using a large, multiuniversity sample (N = 3,172), we evaluated the convergent and discriminant validity and reliability of the ACI. We also evaluated the ACI measure of SCT in relation to self-reported demographic characteristics, daily life executive functioning, socioemotional adjustment (i.e., anxiety/depression, loneliness, emotion dysregulation, self-esteem), and functional impairment. Exploratory confirmatory factor analyses resulted in 10 ACI items demonstrating strong convergent and discriminant validity from both anxiety/depressive and ADHD inattentive symptom dimensions. SCT was moderately to-strongly correlated with daily life EF deficits, poorer socioemotional adjustment, and greater global functional impairment. Moreover, SCT remained uniquely associated in structural regression analyses with most of these external criterion domains above and beyond ADHD. Finally, when internalizing symptoms were also covaried, SCT, but not ADHD inattention, remained significantly associated with poorer socioemotional adjustment. These findings support the use of the ACI in future studies examining SCT in adulthood and make a major contribution in moving the field toward a unified set of SCT items that can be used across studies.
Current reinforcement model reproduces center‐in‐center vein trajectory of Physarum polycephalum

Vein networks span the whole body of the amoeboid organism in the plasmodial slime mould Physarum polycephalum, and the network topology is rearranged within an hour in response to spatio‐temporal variations of the environment. It has been reported that this tube morphogenesis is capable of solving mazes, and a mathematical model, named the ‘current reinforcement rule’, was proposed based on the adaptability of the veins. Although it is known that this model works well for reproducing some key characters of the organism's maze‐solving behaviour, one important issue is still open: In the real organism, the thick veins tend to trace the shortest possible route by cutting the corners at the turn of corridors, following a center‐in‐center trajectory, but it has not yet been examined whether this feature also appears in the mathematical model, using corridors of finite width. In this report, we confirm that the mathematical model reproduces the center‐in‐center trajectory of veins around corners observed in the maze‐solving experiment.
Measuring Self-Efficacy in the Context of Pediatric Diabetes Management: Psychometric Properties of the Self-Efficacy for Diabetes Scale

Objective The Self-Efficacy for Diabetes Scale (SED) is a widely used measure of diabetes-specific self-efficacy with three subscales: diabetes-specific self-efficacy (SED-D), medical self-efficacy (SED-M), and general self-efficacy (SED-G). The present study examined the factor structure and construct validity of the SED in 116 youth, aged 10-16 years (13.60 ± 1.87), with type 1 diabetes mellitus. Methods Confirmatory factor analysis (CFA) was used to examine the factor structure of the SED. Correlational and regression analyses examined relations between subscales and select outcomes. Results CFA of the original three-factor structure provided a poor fit to the data. Factor models using rescaled items were tested. Results provided preliminary evidence for the SED-D as an independent one-factor model, and for a reduced one-factor model. Significant associations were found between the SED subscales, responsibility for diabetes management, and glycated hemoglobin. Conclusions Results provide limited support for the SED-D as a reliable and valid measure of diabetes-specific self-efficacy.
A macromolecular halogen‐free flame retardant and its effect on the properties of thermoplastic polyesters

A halogen‐free flame retardant with a macromolecular structure is presented. Its synthesis proceeds via polymerization of phosphorus‐containing acrylate monomers. The flame retardant was incorporated into poly(ethylene terephthalate) by extrusion. Samples with different concentrations (0.5, 2.5, and 5.0 wt%) as well as a 25 wt% masterbatch were prepared. All samples were transparent and colorless without any visible irregularities. Thermal investigations reveal an unchanged glass transition temperature. Tensile tests show the typical mechanical behavior of poly(ethylene terephthalate), but with an elevated Young's modulus. The burning behavior was investigated by several small‐flame tests in vertical and horizontal orientation, as well as by cone calorimetry. It is shown that samples with 2.5 wt% flame retardant pass the vertical UL94 test (V‐2, 20‐mm flame). The sample cannot be ignited in the horizontal fire test according to FMVSS 302. The oxygen index was measured to 28 vol%. Cone calorimetric measurements show that the effective heat of combustion as well as the total heat evolved is reduced.
Evaluation of Entity Recognition Algorithms in Short Texts

One of the major consequences of the growth of social networks has been the generation of huge volumes of content. The text that is generated in social networks constitutes a new type of content, that is short, informal, lacking grammar in some cases, and noise prone. Given the volume of information that is produced every day, a manual processing of this data is unpractical, causing the need of exploring and applying automatic processing strategies, like Entity Recognition (ER). It becomes necessary to evaluate the performance of traditional ER algorithms in corpus with those characteristics. This paper presents the results of applying AlchemyAPI y Dandelion API algorithms in a corpus provided by The SemEval-2015 Aspect Based Sentiment Analysis Conference. The entities recognized by each algorithm were compared against the ones annotated in the collection in order to calculate their precision and recall. Dandelion API got better results than AlchemyAPI with the given corpus.
Using Derivatives of an Implicit Function to Obtain the Stationary Phase of the Two-Dimensional Spectrum for Bistatic SAR Imaging

There are two square-root terms in the range history of a return signal from a bistatic synthetic aperture radar (BiSAR). The transfer function for imaging in the 2-D frequency or range Doppler domain using the principle of stationary phase cannot be analytically derived. To address this problem, we approximated the stationary phase of the 2-D spectrum with an expansion of the Taylor series on the azimuth frequency and called the approximation as the derivatives of an implicit function (DIF). After algebraic manipulation, the DIF and 2-D spectrum were obtained for a generally configured BiSAR. With the DIF method, we dissolved one square-root term out of the two for an azimuth-invariant BiSAR, which is particularly advantageous in the implementation of an imaging algorithm. Then, a modified range Doppler algorithm was developed to process the BiSAR data. Promising results were obtained.
Consideration of insects as a source of dietary protein for human consumption

Consumption of sufficient dietary protein is fundamental to muscle mass maintenance and overall health. Conventional animal-based protein sources such as meat (ie, beef, pork, lamb), poultry, fish, eggs, and dairy are generally considered high-quality sources of dietary protein because they meet all of the indispensable amino-acid requirements for humans and are highly digestible. However, the production of sufficient amounts of conventional animal-based protein to meet future global food demands represents a challenge. Edible insects have recently been proposed as an alternative source of dietary protein that may be produced on a more viable and sustainable commercial scale and, as such, may contribute to ensuring global food security. This review evaluates the protein content, amino-acid composition, and digestibility of edible insects and considers their proposed quality and potential as an alternative protein source for human consumption.
Target range of motion at 3 months after arthroscopic rotator cuff repair and its effect on the final outcome

Purpose: The postoperative protocol after arthroscopic rotator cuff repair (ARCR) is still controversial. Some surgeons recommend slower rehabilitation in order to improve the integrity of the repair, while others prefer early range-of-motion (ROM) exercise to avoid postoperative stiffness. The purpose of this study was to determine target ROM (T-ROM) measurements at 3 months after ARCR that are predictive of eventual full recovery without structural failure. Methods: The cases consisted of 374 shoulders in 360 patients who underwent primary ARCR and were followed up for at least 2 years. Forward flexion (FF) and side-lying external rotation (ER) were measured preoperatively at 3, 6, 9, 12, and 24 months after surgery, and the patients were divided into six subgroups according to the values for each type of ROM at 3 months (ROM-3M). In each subgroup, the final ROM at 24 months after surgery was compared to determine the T-ROM. The average ROMs with time and re-tear rate were then compared between the under-T-ROM and over-T-ROM groups. Results: The only significant difference in FF was between the 120–129° and 110–119° ROM-3M groups. Therefore, the T-ROM for FF was determined to be 120°. Similarly, the T-ROM for ER was determined to be 20°. Each ROM in the over-T-ROM group was significantly better than that in the under-T-ROM group at all assessments. There was no significant difference in the re-tear rate between the groups. Conclusion: To acquire sufficient ROM in 2 years without high re-tear rate, a target FF of 120° and ER of 20° should be achieved within 3 months after surgery.
Daily stressors, trauma exposure, and mental health among stateless Rohingya refugees in Bangladesh

The Rohingya of Myanmar are a severely persecuted minority who form one of the largest groups of stateless people; thousands of them reside in refugee camps in southeastern Bangladesh. There has been little research into the mental health consequences of persecution, war, and other historical trauma endured by the Rohingya; nor has the role of daily environmental stressors associated with continued displacement, statelessness, and life in the refugee camps, been thoroughly researched. This cross-sectional study examined: trauma history, daily environmental stressors, and mental health outcomes for 148 Rohingya adults residing in Kutupalong and Nayapara refugee camps in Bangladesh. Results indicated high levels of mental health concerns: posttraumatic stress disorder (PTSD), depression, somatic complaints, and associated functional impairment. Participants also endorsed local idioms of distress, including somatic complaints and concerns associated with spirit possession. The study also found very high levels of daily environmental stressors associated with life in the camps, including problems with food, lack of freedom of movement, and concerns regarding safety. Regression and associated mediation analyses indicated that, while there was a direct effect of trauma exposure on mental health outcomes (PTSD symptoms), daily environmental stressors partially mediated this relationship. Depression symptoms were associated with daily stressors, but not prior trauma exposure. These findings indicate that daily stressors play a pivotal role in mental health outcomes of populations affected by collective violence and statelessness. It is, therefore, important to consider the role and effects of environmental stressors associated with life in refugee camps on the mental health and psychosocial well-being of stateless populations such as the Rohingya, living in protracted humanitarian environments.
Predictors, Moderators, and Mediators of Treatment Outcome Following Manualised Cognitive‐Behavioural Therapy for Eating Disorders: A Systematic Review

This systematic review synthesised the literature on predictors, moderators, and mediators of outcome following Fairburn's CBT for eating disorders. Sixty-five articles were included. The relationship between individual variables and outcome was synthesised separately across diagnoses and treatment format. Early change was found to be a consistent mediator of better outcomes across all eating disorders. Moderators were mostly tested in binge eating disorder, and most moderators did not affect cognitive-behavioural treatment outcome relative to other treatments. No consistent predictors emerged. Findings suggest that it is unclear how and for whom this treatment works. More research testing mediators and moderators is needed, and variables selected for analyses need to be empirically and theoretically driven. Future recommendations include the need for authors to (i) interpret the clinical and statistical significance of findings; (ii) use a consistent definition of outcome so that studies can be directly compared; and (iii) report null and statistically significant findings. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.
Induction Therapy With Biosimilar Infliximab in Children With Crohn Disease

Introduction: In most European countries, an infliximab biosimilar (CT-P13) is currently in common use. In vitro and in vivo studies have proved a high similarity between CT-P13 and the reference infliximab. CT-P13 was licensed for use in patients with Crohn disease (CD) based on the extrapolation of data from preclinical studies and clinical trials in rheumatology indications. The aim of this study was to assess the similarity between CT-P13 and the originator infliximab in induction therapy in CD paediatric patients. Methods: Thirty-six CD paediatric patients from 3 Polish academic centres who started biological therapy with CT-P13 were enrolled in this prospective, observational study. Patients received 3 induction doses (5 mg/kg) of CT-P13 at weeks 0, 2, 6. Assessment was performed before the first infusion and at week 14. Results: Overall 34/36 (94.4%) patients completed induction therapy with CT-P13. A clinical response or remission after 3 initial doses was achieved in 31/36 (86%) and 24/36 (67%) of patients, respectively. Clinically and statistically significant decreases in Paediatric Crohn's Disease Activity Index, C-reactive protein, and erythrocyte sedimentation rate were observed in the responders group. An allergic reaction during infusion, which led to treatment discontinuation, was observed in one case. Conclusions: Induction therapy with CT-P13 in children with CD is effective. The profile appears similar to that reported for the reference infliximab. No unexpected adverse events occurred.
Electromigration-Aware Local-Via Allocation in Power/Ground TSVs of 3-D ICs

With increasing temperature and current density, electromigration (EM) becomes a major interconnect reliability concern for 3-D integrated-circuits (3-D ICs). In 3-D power delivery networks, local vias are used inside power/ground (P/G) through-silicon-vias (TSVs) for vertical power delivery, which are susceptible to EM effects. In order to improve the EM reliability of P/G TSVs, it is desirable to insert multiple local vias in each P/G TSV whereby the current density of each local via can be reduced. However, excessive local vias may consume too much routing area, which leads to exacerbated routing congestion and increased delay overhead. In this paper, we propose a design technique to handle this tradeoff between EM reliability of P/G TSVs and timing performance of 3-D ICs. By utilizing an integer-linear-programming formulation, the optimal local-via number in each P/G TSV can be determined to minimize the local via-induced routing congestion while satisfying the given requirement of EM reliability.
Aspirin attenuates spontaneous recurrent seizures in the chronically epileptic mice

Abstract Objective: Neuroinflammatory processes are pathologic hallmarks of both experimental and human epilepsy, and could be implicated in the neuronal hyperexcitability. Aspirin represents one of the non-selective nonsteroidal anti-inflammatory drugs with fewer side effects in long-term application. This study was carried out to assess the anti-epileptic effects of aspirin when administered during the chronic stage of temporal lobe epilepsy [TLE] in mice. The alteration of hippocampal neurogenesis was also examined for raising a possible mechanism underlying the protective effect of anti-inflammatory treatment in the TLE. Methods: Two months after pilocarpine-induced status epilepticus, the chronically epileptic mice were treated with aspirin (20 mg, 60 mg or 80 mg/kg) once a day for 10 weeks. Spontaneous recurrent seizures were monitored by video camera for 2 weeks. To evaluate the profile of hippocampal neurogenesis, the newly generated cells in the dentate gyrus were labeled by the proliferation marker BrdU. The newborn neurons that extended axons to CA3 area were visualized by cholera toxin B subunit retrograde tracing. Results: Administration of aspirin with a dosage of 60 mg or 80 mg/kg initiated at 2 months after pilocarpine-induced status epilepticus significantly reduced the frequency and duration of spontaneous recurrent seizures. Aspirin treatment also increased the number of newborn neurons with anatomic integration through improving the survival of the newly generated cells. Conclusion: Aspirin treatment during the chronic stage of TLE could attenuate the spontaneous recurrent seizures in mice. Promotion of hippocampal neurogenesis and inhibition of COX-PGE2 pathway might partly contribute to this anti-epileptic effect. Highlights• Aspirin attenuates spontaneous recurrent seizures of chronically epileptic mice• Aspirin increases neurogenesis of chronically epileptic hippocampus by improving the survival of newly generated cells• Promotion of hippocampal neurogenesis and inhibition of COX-PGE2 pathway might partly contribute to anti-epileptic effects of aspirin.
The Strategy of PIKing a Target: What Is AKTually Most Effective?

Breast and gynecologic cancers harboring PIK3CA mutations showed no significant responses to AZD5363, a pan-AKT catalytic inhibitor, in contrast with previous in vitro data showing activity of the drug in this subset of cancers. These results raise the question of how to select the most accurate predictive biomarkers of response. Clin Cancer Res; 24(9); 2029–31. ©2018 AACR. See related article by Banerji et al., p. 2050