Miracle-dz/UniFAR-FTUs huggingface dataset:
Recognition of overlapping speech using digital MEMS microphone arrays

This paper presents a new corpus comprising single and overlapping speech recorded using digital MEMS and analogue microphone arrays. In addition to this, the paper presents results from speech separation and recognition experiments on this data. The corpus is a reproduction of the multi-channel Wall Street Journal audio-visual corpus (MC-WSJAV), containing recorded speech in both a meeting room and an anechoic chamber using two different microphone types as well as two different array geometries. The speech separation and speech recognition experiments were performed using SRP-PHAT-based speaker localisation, superdirective beamforming and multiple post-processing schemes, such as residual echo suppression and binary masking. Our simple, cMLLR-based recognition system matches the performance of state-of-the-art ASR systems on the single speaker task and outperforms them on overlapping speech. The corpus will be made publicly available via the LDC in spring 2013.
A study on factors influencing financial literacy and fintech adoption

Financial literacy is gaining significant importance in the recent past. This leads to to the adoption of financial technology services. Current research explores to study the various factors affect the adoption of financial literacy which leading to adoption of fintech services. The research framework include factors include in the study were financial behaviour, financial attitude, financial knowledge, financial capability, financial literacy. Data were obtained form graduate and post graduate students. A total of 229 responses were received based on survey data using five point Likert scale. Findings reported that financial behaviour, financial attitude, financial knowledge and financial capability have shown a significant positive effect on financial literacy. In turn, financial exhibited a positive effect on adoption of fintech services. The results have implications for both academia and research adding to existing literature financial literacy and fintech adoption.
Patient Satisfaction and Efficacy of Full-Facial Rejuvenation Using a Combination of Botulinum Toxin Type A and Hyaluronic Acid Filler

BACKGROUND Combination treatments using hyaluronic acid (HA) fillers and botulinum toxin Type A (BoNT-A) are common in aesthetic medicine; however, this has been evaluated in only a few clinical studies. OBJECTIVE To evaluate subject satisfaction, efficacy, and safety of BoNT-A (Speywood Unit; s.U) and a range of HA fillers for full-facial aesthetic rejuvenation. MATERIALS AND METHODS A 6-month, multicenter, open-label clinical study, using BoNT-A (s.U) and 5 HA fillers to treat up to 13 facial zones. Subject satisfaction questionnaires were administered 3 weeks and 6 months after the last injection. Global aesthetic improvement and improvement on each treated zone as well as safety were evaluated. RESULTS A high level of satisfaction was achieved throughout the study, with 96.5% of subjects at least satisfied with the full-facial aesthetic outcome at 3 weeks, and 92.9% at 6 months. More than 91% considered the treatment outcome to meet or surpass their expectations, and more than 94% would recommend the treatment to others. At Week 3, subject and investigator assessment showed aesthetic improvement for all subjects. The treatment was well tolerated. CONCLUSION The combination of BoNT-A (s.U) and HA fillers results in high patient satisfaction and in an overall improvement of aesthetic outcomes and quality of life.
Collective Narcissism and Intergroup Hostility: The Dark Side of ‘In‐Group Love’

This paper reviews current research on intergroup consequences of collective narcissism – an emotional investment in an unrealistic belief in exaggerated greatness of an in-group. Integrating findings of the psychology of intergroup relations with findings regarding psychological outcomes of individual narcissism, the collective narcissism construct addresses the relationship between ‘in-group love’ and ‘out-group hate’. Differentiating between narcissistic and genuine positive group regard uncovers the potential of genuine ‘in-group’ love to motivate positive out-group attitudes and intergroup tolerance. Collective narcissism is also shown to be the aspects of positive group attachment that inspires defensive and retaliatory intergroup hostility under perceived threat. Narcissistic idealization of an in-group is contingent on external validation and underlain by internal doubts. Collective narcissists are never fully satisfied with external acknowledgement of the in-group and they are sensitive to anything that may undermine the in-group’s exaggerated image.
Korean mothers' intuitive theories regarding emotion socialization of their children

This study aims at exploring Korean mothers' beliefs on the development of emotion of their children. In specific, sensitivity and maternal reactions to their children's both negative and positive emotion expressions were explored. Further, associations among maternal sensitivity, maternal reactions and child emotion regulation were examined. A total of 100 Korean mothers whose children were between 6 and 7 years old participated in the study. In order to assess mothers' beliefs about sensitivity, vignettes in a forced-choice format were presented through individual interviews. Mothers' self reported reactions to their children's negative emotions and positive emotions and mothers' perceptions of children's emotion regulation were assessed using questionnaires. Results revealed that Korean mothers endorsed both proactive and reactive sensitivity. However, their sensitivity differed depending on the situation. Mothers tended to endorse either Emotion Focused or Problem Focused reactions to their children's negative emotions. Mothers reported that they were most likely to restrict their child positive emotional expression with explanation in supportive way followed by invalidating through reprimanding it. Mothers' reported Distress Reactions and Punitive Reactions to children's expression of negative emotion were associated with children's liability whereas Emotion-Focused Reaction and Problem-Focused Reaction were associated with children's functional emotion regulation. The results are discussed within a theoretical framework of socialization of emotions.
Design, Implementation, and Evaluation at Entry of a Prospective Cohort Study of Homosexual and Bisexual HIV‐1‐Negative Men in Belo Horizonte, Brazil: Project Horizonte

Background and Objectives: Project Horizonte, an open cohort of homosexual and bisexual HIV‐1‐negative men, is a component of the Minas Gerais AIDS Vaccine Program of the Federal University of Minas Gerais, Belo Horizonte, Brazil. Its objectives included the evaluation of seroincidence of HIV, to ascertain the role of counseling on behavior modification and to assess their willingness to participate in future HIV vaccine trials. Methods: Various means of recruitment were used, including pamphlets, notices in community newspapers, radio, and television, at anonymous testing centers, and by word of mouth. Results: From October 1994 to May 1999, 470 volunteers were enrolled. Their mean age was 26 years and over 70% of them had high school or college education. During the follow‐up, they were seen every 6 months, when they received counseling and condoms, and when HIV testing was done. Eighteen seroconversions were observed, and the incidence rates estimates were 1.75 per 100 and 1.99 per 100 personyears, for 36 and 48 months of follow‐up, respectively. During the entire period, 139 volunteers were lost to follow‐up. Among them, 59 (42.4%) never returned after the initial visit and 51 (36.7) came only once after their initial visit. No losses were observed for those observed during follow‐up for more than 3 years. At enrollment, 50% of participants said they would participate in a vaccine trial, and 30% said they might participate. Conclusions: The results obtained up to this moment confirm the feasibility of following this type of cohort for an extended period, estimating HIV incidence rate, and evaluating counseling for safe sexual practices in preparation for clinical trials with candidate HIV vaccines in Brazil.
Closing the mass budget of a tidewater glacier: the example of Kronebreen, Svalbard

In this study, we combine remote sensing, in situ and model-derived datasets from 1966 to 2014 to calculate the mass-balance components of Kronebreen, a fast-flowing tidewater glacier in Svalbard. For the well-surveyed period 2009–2014, we are able to close the glacier mass budget within the prescribed errors. During these 5 years, the glacier geodetic mass balance was −0.69 ± 0.12 m w.e. a−1, while the mass budget method led to a total mass balance of −0.92 ± 0.16 m w.e. a−1, as a consequence of a strong frontal ablation (−0.78 ± 0.11 m w.e. a−1), and a slightly negative climatic mass balance (−0.14 ± 0.11 m w.e. a−1). The trend towards more negative climatic mass balance between 1966–1990 (+0.20 ± 0.05 m w.e. a−1) and 2009–2014 is not reflected in the geodetic mass balance trend. Therefore, we suspect a reduction in ice-discharge in the most recent period. Yet, these multidecadal changes in ice-discharge cannot be measured from the available observations and thus are only estimated with relatively large errors as a residual of the mass continuity equation. Our study presents the multidecadal evolution of the dynamics and mass balance of a tidewater glacier and illustrates the errors introduced by inferring one unmeasured mass-balance component from the others.
Topical Word Embeddings

Most word embedding models typically represent each word using a single vector, which makes these models indiscriminative for ubiquitous homonymy and polysemy. In order to enhance discriminativeness, we employ latent topic models to assign topics for each word in the text corpus, and learn topical word embeddings (TWE) based on both words and their topics. In this way, contextual word embeddings can be flexibly obtained to measure contextual word similarity. We can also build document representations, which are more expressive than some widely-used document models such as latent topic models. In the experiments, we evaluate the TWE models on two tasks, contextual word similarity and text classification. The experimental results show that our models outperform typical word embedding models including the multi-prototype version on contextual word similarity, and also exceed latent topic models and other representative document models on text classification.
Quotient Spaces of Boundedly Rational Types

By identifying types whose low-order beliefs – up to level li – about the state of nature coincide, we obtain quotient type spaces that are typically smaller than the original ones, preserve basic topological properties, and allow standard equilibrium analysis even under bounded reasoning. Our Bayesian Nash (li; l-i)-equilibria capture players’ inability to distinguish types belonging to the same equivalence class. The case with uncertainty about the vector of levels (li; l-i) is also analyzed. Two examples illustrate the constructions.
Purification and Identification of G Protein-coupled Receptor Protein Complexes under Native Conditions*S

G protein-coupled receptors (GPCRs) constitute the largest family of membrane receptors and are of major therapeutic importance. The identification of GPCR-associated proteins is an important step toward a better understanding of these receptors. However, current methods are not satisfying as only isolated receptor domains (intracellular loops or carboxyl-terminal tails) can be used as “bait. ” We report here a method based on tandem affinity purification coupled to mass spectrometry that overcomes these limitations as the entire receptor is used to identify protein complexes formed in living mammalian cells. The human MT1 and MT2 melatonin receptors were chosen as model GPCRs. Both receptors were tagged with the tandem affinity purification tag at their carboxyl-terminal tails and expressed in human embryonic kidney 293 cells. Receptor solubilization and purification conditions were optimized. The method was validated by the co-purification of Gi proteins, which are well known GPCR interaction partners but which are difficult to identify with current protein-protein interaction assays. Several new and functionally relevant MT1- and MT2-associated proteins were identified; some of them were common to both receptors, and others were specific for each subtype. Taken together, our protocol allowed for the first time the purification of GPCR-associated proteins under native conditions in quantities suitable for mass spectrometry analysis.
Work-related peak flow and asthma symptoms in a damp building.

BACKGROUND Working in damp conditions is associated with asthma, but few studies have used objective testing to document work-related patterns. AIMS To describe the relationship of peak flow measurements to work-related asthma (WRA) symptoms and WRA among occupants in a damp office building. METHODS At the beginning of the study, all workers were offered a questionnaire and methacholine challenge testing. Participants were then instructed to perform serial spirometry using handheld spirometers five times per day over a 3 week period. Peak flow data were analysed using OASYS-2 software. We calculated the area between the curves (ABC score) using hours from waking. We considered a score >5.6 L/min/h to be indicative of a work-related pattern. RESULTS All 24 employees participated in the questionnaire. Seven participants (29%) reported physician-diagnosed asthma with onset after starting work in the building. Almost two-thirds (63%) of participants reported at least one lower respiratory symptom (LRS) occurring one or more times per week in the last 4 weeks. Twenty-two (92%) consented to participate in serial spirometry. Fourteen participants had adequate quality of serial spirometry, five of whom had ABC scores >5.6, ranging from 5.9-23.0. Of these five, two had airways responsiveness, three had current post-hire onset physician-diagnosed asthma and four reported work-related LRS. CONCLUSIONS We found evidence of work-related changes in serial peak flows among some occupants of an office building with a history of dampness. Serial peak flows may be a useful measure to determine WRA in office settings.
ANALYSIS OF EARNINGS QUALITY IN PHARMACEUTICAL SUB-SECTOR COMPANIES LISTED ON THE INDONESIAN STOCK EXCHANGE

Earnings quality is the accuracy of performance data that must be reported in the company's financial statements and shows the actual financial condition, so that earnings that are open to the public can show how much the company's profits affect decisions and can be used by shareholders when evaluating company performance. This analysis has the aim of knowing whether Investment Opportunity Set, capital structure and profitability affect the quality of earnings in pharmaceutical sub-sector companies listed on the IDX for the period 2017-2022. There are 12 populations in pharmaceutical companies, obtained as many as 5 companies as samples using purposive sampling technique. The method of analysis is multiple linear regression analysis. The results prove that simultaneously 10S, capital structure, and profitability have a significant effect on earnings quality. Partially 105 affects earnings quality, capital structure affects earnings quality, and profitability has no effect on earningsquality.
A general framework for measuring system complexity

In this work, we are motivated by the observation that previous considerations of appropriate complexity measures have not directly addressed the fundamental issue that the complexity of any particular matter or thing has a significant subjective component in which the degree of complexity depends on available frames of reference. Any attempt to remove subjectivity from a suitable measure therefore fails to address a very significant aspect of complexity. Conversely, there has been justifiable apprehension toward purely subjective complexity measures, simply because they are not verifiable if the frame of reference being applied is in itself both complex and subjective. We address this issue by introducing the concept of subjective simplicity—although a justifiable and verifiable value of subjective complexity may be difficult to assign directly, it is possible to identify in a given context what is “simple” and, from that reference, determine subjective complexity as distance from simple. We then propose a generalized complexity measure that is applicable to any domain, and provide some examples of how the framework can be applied to engineered systems. © 2016 Wiley Periodicals, Inc. Complexity, 2016
Presynaptic Gating of Postsynaptically Expressed Plasticity at Mature Thalamocortical Synapses

Thalamocortical (TC) projections provide the major pathway for ascending sensory information to the mammalian neocortex. Arrays of these projections form synaptic inputs on thalamorecipient neurons, thus contributing to the formation of receptive fields (RFs) in sensory cortices. Experience-dependent plasticity of RFs persists throughout an organism's life span but in adults requires activation of cholinergic inputs to the cortex. In contrast, synaptic plasticity at TC projections is limited to the early postnatal period. This disconnect led to the widespread belief that TC synapses are the principal site of RF plasticity only in neonatal sensory cortices, but that they lose this plasticity upon maturation. Here, we tested an alternative hypothesis that mature TC projections do not lose synaptic plasticity but rather acquire gating mechanisms that prevent the induction of synaptic plasticity. Using whole-cell recordings and direct measures of postsynaptic and presynaptic activity (two-photon glutamate uncaging and two-photon imaging of the FM 1-43 assay, respectively) at individual synapses in acute mouse brain slices that contain the auditory thalamus and cortex, we determined that long-term depression (LTD) persists at mature TC synapses but is gated presynaptically. Cholinergic activation releases presynaptic gating through M1 muscarinic receptors that downregulate adenosine inhibition of neurotransmitter release acting through A1 adenosine receptors. Once presynaptic gating is released, mature TC synapses can express LTD postsynaptically through group I metabotropic glutamate receptors. These results indicate that synaptic plasticity at TC synapses is preserved throughout the life span and, therefore, may be a cellular substrate of RF plasticity in both neonate and mature animals.
Predictive Value of Acute Kidney Injury in Medical Intensive Care Patients With Sepsis Originating From Different Infection Sites

Introduction: Sepsis is the most common noncoronary cause of mortality in intensive care units (ICUs). This study compared different systems for predicting outcomes in a population of critically ill patients with sepsis originating from different infection sites, including intra-abdominal and pulmonary infections. Methods: This post hoc analysis of an accumulated database enrolled 161 heterogeneous critically ill patients diagnosed as severe sepsis and septic shock patients admitted to medical ICUs from June 2005 to May 2007. Demographic characteristics, clinical and laboratory variables, comorbidities and infection source were prospectively recorded on the first day of ICU admission. Patient evaluations included acute physiology and chronic health evaluation (APACHE) II, APACHE III, sequential organ failure assessment scores, organ system failure and risk of renal failure, injury to kidney, failure of kidney function, loss of kidney function and end-stage renal failure (RIFLE) classification. Results: Regarding the different originating sites of severe sepsis, intra-abdominal infections and pulmonary infections had the highest mortality rates (83.3% and 48.5%, respectively; P < 0.001). The APACHE III was the best mortality predictor for the overall sepsis population [areas under the receiver operating characteristic curve (AUROC) 0.800], whereas RIFLE classification was the best predictor in those with intra-abdominal infection (AUROC 0.856). The AUROC analyses verified that RIFLE classification had significantly (P < 0.05) better discriminatory power for predicting hospital mortality in patients with intra-abdominal infections than in those with pulmonary infections (AUROC 0.545). Conclusions: This investigation confirms that different infection sites have different outcomes. In terms of mortality prediction, outcome scoring systems are significantly more accurate in patients with intra-abdominal infections than in those with pulmonary infections.
The relationship between RASSF1A promoter methylation and thyroid carcinoma

Background: DNA promoter methylation can suppresses gene expression and shows an important role in the biological functions of Ras association domain family 1A (RASSF1A). Many studies have performed to elucidate the role of RASSF1A promoter methylation in thyroid carcinoma, while the results were conflicting and heterogeneous. Here, we analyzed the data of databases to determine the relationship between RASSF1A promoter methylation and thyroid carcinoma. Methods: We used the data from 14 cancer–normal studies and Gene Expression Omnibus (GEO) database to analyze RASSF1A promoter methylation in thyroid carcinoma susceptibility. The data from the Cancer Genome Atlas project (TCGA) database was used to analyze the relationship between RASSF1A promoter methylation and thyroid carcinoma susceptibility, clinical characteristics, prognosis. Odds ratios were estimated for thyroid carcinoma susceptibility and hazard ratios were estimated for thyroid carcinoma prognosis. The heterogeneity between studies of meta-analysis was explored using H, I2 values, and meta-regression. We adopted quality criteria to classify the studies of meta-analysis. Subgroup analyses were done for thyroid carcinoma susceptibility according to ethnicity, methods, and primers. Results: Result of meta-analysis indicated that RASSF1A promoter methylation is associated with higher susceptibility to thyroid carcinoma with small heterogeneity. Similarly, the result from GEO database also showed that a significant association between RASSF1A gene promoter methylation and thyroid carcinoma susceptibility. For the results of TCGA database, we found that RASSF1A promoter methylation is associated with susceptibility and poor disease-free survival (DFS) of thyroid carcinoma. In addition, we also found a close association between RASSF1A promoter methylation and patient tumor stage and age, but not in patients of different genders. Conclusions: The methylation status of RASSF1A promoter is strongly associated with thyroid carcinoma susceptibility and DFS. The RASSF1A promoter methylation test can be applied in the clinical diagnosis of thyroid carcinoma.