Miracle-dz/UniFAR-FTUs huggingface dataset:
Salvage of chronic instability of the syndesmosis with distal tibiofibular arthrodesis: functional and radiographic results.

BACKGROUND Failure to treat an injury of the syndesmosis after an ankle fracture can lead to a poor functional outcome and posttraumatic arthritis. The results after reconstruction of an ankle with an incongruous mortise, chronic diastasis of the syndesmosis, and arthritis remain unknown. The purpose of the present study was to review the radiographic and clinical results of salvaging this condition through reduction and arthrodesis of the distal tibiofibular articulation. METHODS Ten patients (mean age, fifty-four years) with chronic syndesmotic instability who underwent salvage by a single surgeon were evaluated retrospectively. Five parameters of mortise and syndesmotic alignment were measured on weight-bearing radiographs that were made preoperatively and at the time of the latest follow-up. The extent of arthritis in the ankle was graded with use of an established classification system. Clinical rating scores that were recorded preoperatively and at the time of the latest follow-up were culled from the medical records and were compared. Each patient's stated satisfaction with the operation and willingness to undergo the operation again were retrieved from the medical records. RESULTS After a mean duration of follow-up of forty-one months (minimum, two years), the medial clear space, talocrural angle, and talar tilt had improved. No ankle demonstrated progression of arthritis on the basis of the radiographic grade. The clinical rating score improved significantly because of improvements in the pain, activity, maximum walking distance, and gait subscales. Two patients had a total of three additional procedures. Both had prominent implants removed, and one subsequently underwent an ankle arthroscopy. All patients reported satisfaction with and a willingness to undergo the procedure again. At the time of the latest follow-up, no patient had undergone an ankle arthrodesis. CONCLUSIONS The significant improvements in the radiographic and functional measures of outcome that were observed in this small cohort suggest that chronic syndesmotic instability after ankle fracture can be salvaged with reduction and arthrodesis of the distal tibiofibular articulation. Furthermore, the reconstruction of an incongruous and arthritic ankle is an alternative to and may postpone the subsequent need for ankle arthrodesis or arthroplasty.
A new prosody annotation protocol for live sports commentaries

This paper proposes a new prosody annotation protocol specific to live sports commentaries. Two levels of annotation are defined with HMM-based speech synthesis in view. Local labels are assigned to all syllables and refer to accentual phenomena. Global labels classify sequences of words into five distinct subgenres, defined in terms of valence and arousal. The objective of the study is to provide a set of labels both related to a specific function and characterized by a distinct acoustic realization. The consideration of these constraints should allow for an automatic prediction of the labels both from the text or from the speech signal. Reasonable inter-annotator scores are achieved for both annotation levels. A prosodic analysis of all labels also shows that they can usually be distinguished by specific acoustic realizations. The integration of this new annotation protocol within HMM-based speech synthesis shows promising results.
Longitudinally extensive myelopathy in Caucasians: a West Australian study of 26 cases from the Perth Demyelinating Diseases Database

Objectives To characterise West Australian cases of longitudinally extensive myelopathy (LEM). Methods Twenty six patients with LEM were identified from a cohort of 983 patients with demyelinating disease. Clinical and MRI data and AQP4-IgG results were reviewed. Results LEM cases were classified as conventional MS (CMS) 13, neuromyelitis optica (NMO) 7, and isolated LEM 6. LEM was the initial presentation in 13/26 cases. In CMS cases lesions were mainly in the lower cervical cord (C4–C7) whereas in NMO and isolated LEM they were more often thoracic and were longer. The severity of disability was highly variable but was greater in the NMO than the CMS group. Only one of 20 patients tested was seropositive for AQP4-IgG. Conclusion LEM occurred as part of CMS or NMO or in isolation. Patients with LEM had highly heterogeneous clinical characteristics and a low rate of AQP4-IgG seropositivity.
▼Lurasidone for schizophrenia

▼Lurasidone (Latuda—Sunovion) is a new oral second-generation antipsychotic licensed for treating adults with schizophrenia. Although less likely to cause extrapyramidal adverse effects than first-generation antipsychotics, some second-generation antipsychotics cause weight gain that may increase the risk of diabetes, hypertension and raised lipid levels.1,2 Lurasidone is promoted as offering a balance between efficacy and tolerability, with reported negligible effects on weight and minimal effects on glucose and cholesterol.3 Here we review evidence for lurasidone's efficacy and safety, and consider how it compares with other antipsychotics.
Context receptivity: innovation in an amateur sport organization.

The Amateur Boxing Association (ABA) is a Canadian provincial sport organization. Recently, the ABA has attempted many innovations in response to strong pressure for change. The success of these attempts has been mixed. This study uses Pettigrew, Ferlie and McKee's (1992) metaphor of context receptivity to explain this outcome variability. Context receptivity is a process-oriented perspective on organizational change behavior. This research is a qualitative, ethnographic case study focussing on two particular ABA innovations. One innovation failed; the other succeeded. These results are consistent with the expectations of context receptivity, which is a useful framework for understanding change outcomes in sport organizations.
Auf den Lehrer kommt es an. Empirische Evidenzen für Zusammenhänge zwischen Lehrerkompetenzen, Lehrerhandeln und dem Lernen der Schüler

Die Lehrer haben durch ihre Kompetenzen und ihr Handeln insbesondere durch ihr Wissen und ihre Uberzeugungen einen entscheidenden Einfluss auf die Lernentwicklung der Schuler. Die dargestellten Ergebnisse zeigen, dass ein Unterricht, der sich durch einen geringen Grad an Lehrersteuerung und durch starker zielorientierte, kooperative Arbeitsformen auszeichnet, sich in seiner Effektivitat steigern lasst, wenn die Schuler uber entsprechende Techniken und Kompetenzen zur selbstandigen Arbeit verfugen. Diese sollten trainiert werden. Daruber hinaus kommt es darauf an, dass der Lehrer in schulerorientierten Phasen der Lernarbeit eine aktive Rolle als Mediator spielt. (DIPF/Sch.)
The cellular networks of normal ovine medial collateral and anterior cruciate ligaments are not accurately recapitulated in scar tissue

The purpose of this study was to characterize the cellular organization of the ovine medial collateral ligament (MCL) and anterior cruciate ligament (ACL) and compare this organization with that found in ligaments undergoing healing. Indirect immunofluorescence microscopy, used in combination with antibodies to cytoskeletal proteins, was employed to visualize individual ligament cells. Normal ligaments contained fusiform cells arranged in rows, which were stacked at regular intervals across the body of the ligament forming a three‐dimensional cellular lattice. Each cell exhibited prominent cytoplasmic processes that extended for long distances through the extracellular matrix to adjacent cells, and these processes contained gap junctions. Thus the cells in rows and between rows were interconnected. The cells of the MCL and ACL scars were also arranged in rows, but these rows were shorter, irregularly arranged and closely packed into bundles resulting in tissue with a higher cellular density. In addition, cells transiting the cell cycle were detected in the scar but not in normal ligament. While the rows of cells in the normal ligament extended along the long axis of the ligament, the bundles of rows of ligament scar cells had a random orientation with respect to one another and to the region outside the scar. Over time both the ACL and the MCL scars displayed discontinuities in their cellular rows. In contrast to the scars of the MCL, which contained discontinuities filled with cellular projections and gap junctions, ACL scars contained discontinuities that were devoid of cells and gap junctions. These discontinuities as well as the differences between normal and scar cytoarchitecture may represent features of an inadequate healing response and/or may provide the structural basis for the altered biomechanics of healing ligaments.
Uso de álcool, tabaco e outras drogas entre estudantes universitários brasileiros

CONTEXTO: Pesquisas tem demonstrado que a entrada na universidade e um periodo critico, de vulnerabilidade para o inicio e a manutencao do uso de alcool e outras drogas. No Brasil, grandes levantamentos domiciliares e entre estudantes do ensino medio foram realizados nos ultimos 20 anos; porem, os levantamentos referentes ao consumo de drogas entre universitarios sao representados por dados dos ultimos dez anos. OBJETIVOS: Revisar a evolucao desses estudos e relaciona-los aos principais resultados encontrados, referindo a necessidade de novos levantamentos para estimativa do perfil e prevalencia dos universitarios diante do consumo de drogas no contexto estudado. METODOS: Revisao bibliografica das bases de dados MEDLINE, LILACS, PubMed e Scirus de 1997 a 2007. RESULTADOS: Foram encontradas 12 publicacoes referentes ao consumo de drogas entre universitarios brasileiros. Estao apresentados como estudos de prevalencia de uso e estudos de comportamentos de risco, os quais nao caracterizam fidedignamente essa populacao. CONCLUSOES: Ha necessidade de estudos que viabilizem a comparacao dos resultados, possibilitem adequacoes de programas de prevencao nessa comunidade, auxiliem na melhoria da qualidade de vida e desenvolvam novas frentes preventivas. A repeticao podera informar como as variaveis se comportam ao longo do tempo e se possibilitam avaliar tendencias vindo a constituir estudos seriados.
Factors influencing information privacy concern in cloud computing environment

Cloud computing technology is one of the newest technologies widely used by consumers globally due to its advantages. One of the common advantages is that users can get access to applications and their own files and data on demand. However, there are privacy concerns and issues which discourage users from being active in cloud computing. This paper attempts to investigate the factors that influence information privacy concern in cloud computing environment by using a quantitative research approach. A total of 340 cases were gathered from a sampled population of students. Based on SPSS analysis, the study found that perceived privacy risk is influencing information privacy concern in cloud computing environment. Meanwhile, perceived privacy control and perceived effectiveness of privacy policy have no significant impact on information privacy concern in cloud computing environment.
Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines

Abstract Sex hormone imbalance is causally related with visceral adipose tissue (AT) dysfunction and visceral obesity – an etiological component of metabolic syndrome (MetS), associated with high risk of both cardiovascular disease (CVD) and type 2 diabetes. In general, premenopausal women appear to be protected from CVD and the dramatic decline in sex steroid hormone occurring during menopausal transitions or other sex-related disorders influence the regional distribution, function, and metabolism of AT and increase the risk of CVD. Visceral AT dysfunction, manifesting as abnormality of fatty acid metabolism, increased oxidative stress, endothelial dysfunction, and excessive production of adipokines have been proposed in the pathogenesis of MetS. However, direct evidence of molecular mechanisms of depot-specific AT alterations, and dysfunction causally related to MetS is limited in studies on postmenopausal women due to difficulty in collecting discrete AT specimens at different ages and repeated sampling from different fat depots. This can be overcome using animal models that can mimic the cluster of pathology leading to MetS and help establish the molecular basis of links between loss of gonadal function on various AT depots and their contribution to MetS. Our group used sex hormone imbalance FSH receptor knock out (FORKO) female mice to recapitulate different aspects of the MetS and addressed the mechanism of visceral obesity related to MetS and discover two novel sex steroid hormone-regulated deep mesenteric estrogen-dependent adipose (MEDAs) genes. Taken together, such recent studies raise hopes for pharmacologic intervention strategies targeting sex steroid hormone signaling in AT to provide protection against AT dysfunction.
Penerapan “Caregiver Skill Program” untuk Mereduksi Inatensi pada Anak ADHD

Parents attempt to resolve inattention symptom problem in child with ADHD. This research involves a major redesigning of parenting techniques into a medication-free approach called the Caregiver Skill Program (CSP). This study focuses to reduce attention deficit in ADHD child with Caregiver Skill Program (CSP). CSP is a skill method where parents give child considerable attention and assistance by giving time out sanction. When CSP was done at home, parents always got feedback written in the daily report card everyday from the class teacher. The subject of the research is a boy, aged 9 years old. He is an ADHD child based on DSM IV. The method of the research was a single subject design (ABC with 1 month follow up). After the parents were trained and began implementing the CSP, inattention as a target behavior seemed decrease. After one month follow up, it indicated that the attention of the this child had improved and be stable . The result of the study showed that CSP may reduce the attention deficiency of ADHD child. Key words : CSP; parent home-based management; inattention; the daily report card; time out
The First Turkish Case of Hypoparathyroidism, Deafness and Renal Dysplasia (HDR) Syndrome

Hypoparathyroidism, deafness and renal dysplasia (HDR) syndrome is an autosomal dominant genetic disorder characterized by hypoparathyroidism, sensorineural deafness and renal dysplasia. We herein present the first Turkish patient with HDR syndrome, who has a p.R367X mutation. This report indicates that p.R367X is not a mutation specific for the Far Eastern populations and also that urological findings in infants with hypoparathyroidism should be carefully examined because clinical findings relating to the p.R367X mutation may show a variable age of onset.
An Iranian Normative Sample of the Color Trails Test

The aim of the present study was to evaluate the psychometric properties of the Color Trail Test (CTT) in an Iranian sample. Six hundred seventeen healthy participants (311 male [50.4%] and 306 female [49.6%]) were assessed. The stepwise regression analysis showed that age and education significantly predicted completion time on the CTT. The percentiles for the 2 parts of the CTT (CTT-A and CTT-B) are presented based on age and education. The older subjects who had less education had lower test completion times. To determine the reliability of the CTT, the participants were tested again 4 weeks later. The correlation coefficients between the first performance and retest were . 909 and . 912 for the CCT-A and CTT-B, respectively. These results suggest that the CTT is a valid and reliable tool that can be applied in Iranians.
Infinite limits of the duplication model and graph folding

We study infinite limits of graphs generated by the duplication model for biological networks. We prove that with probability 1, the sole nontrivial connected component of the limits is unique up to isomorphism. We describe certain infinite deterministic graphs which arise naturally from the model. We characterize the isomorphism type and induced subgraph structure of these infinite graphs using the notion of dismantlability from the theory of vertex pursuit games, and graph homomorphisms. Much recent attention has focused on stochastic models of real-world massive self-organizing networks. The reader is directed to the two recent surveys (1, 2). In self-organizing networks, each node acts as an independent agent, which will base its decision on how to link to the existing network on local knowledge. As a result, the neighbourhood of a new node will often be similar to that of an existing node. An important example of such a network consists of the protein-protein interactions in a living cell. The duplication model of (7) was designed to model such biological networks. The two parameters of the model are a real number p 2 (0,1), and a finite undirected graph H. New nodes are introduced over a countable sequence of discrete time-steps, with the graph at G0 at time t = 0 equalling H. At time t + 1, a node u is chosen uniformly at random from the existing nodes in Gt. To form Gt+1, a new node vt+1 is added. For each of the neighbours z of u, we add the edge zvt+1 to the edges of Gt+1 with probability p. In this paper, we study the infinite graphs that result when time is allowed to go to infinity. The study of infinite limits of random graph models can give new insight into the properties of the model. If p 2 (0,1), then the classical results of Erd˝
Guided Self-Help as Intervention for Traumatic Stress in Parents of Children with Cancer: Conceptualization, Intervention Strategies, and a Case Study

Being a parent of a child diagnosed with cancer poses an enormous stressor. Indeed, several parents have difficulties adjusting to such a situation and react with symptoms of traumatic stress, depression, and reduced quality of life. However, there is little conceptual work on behavioral mechanisms that contribute to suboptimal adaptation in these parents. The authors present a conceptualization in which experiential avoidance and rumination are suggested to contribute to increased levels of traumatic stress and suboptimal adaption. Based on this conceptualization, a recently developed intervention for parents of children with cancer, in the form of guided self-help, is presented. Finally, the authors present a successful case study as an example of the application of this intervention. Clinical implications and suggestions for future research are discussed.
Feedback in Questioning and Marking: The Science Teacher's Role in Formative Assessment

This article describes some outcomes of a project in which teachers from six schools worked with a group at King’s College to develop formative assessment in their science classrooms. Much of the description uses extracts from the teachers’ own accounts of their experiences. Three main areas of work are discussed, namely questioning in classroom dialogue, the quality of such questions, and the giving of feedback on homework by way of comments with no marks. Overall, teachers saw that the changes were transferring more of the responsibility for the learning work to the students. A later article will describe changes in the student’s role.
Do emotional and behavioural difficulties in primary school predict adolescent victimisation trajectories?

Chronic victimisation in adolescence is a traumatic experience with potential negative long-term health consequences. Given that victimisation has been shown to increase over the transition from primary to secondary school, longitudinal data from 1810 students transitioning from primary to secondary school were used to identify victimisation trajectory groups; classified as low-increasing, low-stable, medium-stable and not-bullied. Males with emotional and behavioural difficulties (both internalising and externalising behaviours) and females with externalising behaviours were more likely to be in the increasing and stable victimised groups than the not-bullied group. The results of this study suggest whole-school bullying intervention programmes need to occur before students reach secondary school, and that transition programmes need to emphasise and support social interaction between peers to reduce victimisation and the harms caused by long-term exposure to bullying.
Medication adherence and hospitalization among patients with schizophrenia treated with antipsychotics.

OBJECTIVE This analysis assessed rates of medication adherence and predictors of nonadherence and hospitalization among patients treated with long-acting injectable and oral antipsychotic therapies. METHODS Data were from a retrospective analysis of Florida Medicaid recipients with schizophrenic disorder (ICD-9-CM code 295.XX) who received a prescription for an antipsychotic between July 1, 2004, and June 30, 2005. Patients were required to have filled one additional antipsychotic prescription during follow-up. Adherence measures included medication possession ratio (MPR), medication persistence, medication consistency, and maximum gap in treatment. Multivariate logistic regression models identified predictors of nonadherence and hospitalization. RESULTS Patients were considered adherent if they had an MPR ≥ . 8. A total of 12,032 patients met selection criteria. The mean ± SD MPR was . 79 ± . 23, medication persistence was 94.1% ± 16.4%, medication consistency was 83.3% ± 16.4%, and the maximum gap in treatment was 29.7 ± 41.4 days. Thirty-seven percent of patients were hospitalized for any cause, and 32% had a psychiatric hospitalization. Predictors of nonadherence included newly starting treatment; younger age; a substance abuse diagnosis; use of a mood stabilizer, antidepressant, anxiolytic, or anticholinergic; and receipt of long-acting first-generation antipsychotics. Receipt of long-acting second-generation therapy or receipt of both first- and second-generation medications was associated with lower likelihood of nonadherence. Predictors of hospitalization risk included a diagnosis of other psychoses or substance abuse, anticholinergic use, and nonadherence to therapy. CONCLUSIONS Results document rates of antipsychotic adherence and predictors of nonadherence and hospitalization. Findings may be useful to health plan administrators, formulary decision makers, and physicians.
Personal Educational Planning at Secondary School: Vision and Voice

iii ACKNOWLEDGEMENTS . v LIST OF FIGURES . xiii LIST OF TABLES . xv CHAPTER ONE: Pathways to . 1 Defining an Educational Trajectory . 2 Educational Policy Reform and Personal Educational Planning . 4 The New Zealand Background to the Study . 6 Teachers’ Roles in PEP . 7 The Research and the Researcher . 8 Early School Days . 9 Teaching . 11 The Significance of the Research Topic . 12 Student Voice . 12 The Structure of the Thesis . 13 CHAPTER TWO: The Learner: Position and Educational Change . 15 The Purpose(s) of Schooling: A Shifting Discourse . 16 The Student, the System and the World of Work . 16 Investment in Secondary Education . 17 Students’ Educational Pathways Emerge as a Problem . 19 The Student and the Neoliberal State . 21 Transition Education and Disadvantaged Groups . 23 The Precariat Student . 26 The Emergence of Student Support Programmes in the Twentieth Century . 26 A New Century . 29 The Counselling ‘Gap’ in Aotearoa/New Zealand . 31 Positioning of the Secondary School Student . 33 Cultural Capital and Institutional Habitus . 34 Culturally Responsive Teaching . 35 Perceptions of Today’s Learners . 37 Lifelong Learning . 39 Student Voice, Roles and Rights to Participate . 40 The Voices of Young Māori . 42 Chapter Summary . 43 The Next Chapter . 44 CHAPTER THREE: What Really is Behind PEP? 45 Bronfenbrenner’s Systems Framework and PEP . 46