Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship between coronary atherosclerosis plaque characteristics and high sensitivity C-reactive proteins, interleukin-6.

BACKGROUND The relationship between inflammatory markers and the characteristics of coronary atherosclerosis plaques is uncertain. The aim of the present study was to evaluate the relationship between the characteristics of coronary atherosclerosis plaques and inflammatory markers such as high sensitivity C-reactive proteins (Hs-CRP) and interleukin-6 (IL-6). METHODS All patients suspected of having coronary heart disease (CHD) underwent Siemens 64-slice CT angiography (64-SCTA) to distinguish the quality of plaque of coronary artery lesions. Blood samples were taken to measure levels of serum Hs-CRP and IL-6 in different plaque groups and the control group and compared with the value of 64-SCTA for detection of coronary artery plaque. RESULTS The sensitivity of detecting coronary artery plaque by 64-SCTA was 87.4%, the specificity was 87.1%, the positive predictive value was 82.2%, and the negative predictive value was 91.0%. Comparing the levels of serum Hs-CRP and IL-6 among plaque groups, the mean levels of serum Hs-CRP and IL-6 in three plaque groups were significantly higher than those in the control group (P < 0.01). The mean levels of serum Hs-CRP and IL-6 in the soft plaque group and mixed plaque group were significantly higher than those in hard plaque group (P < 0.01). Plaque burden in the soft plaque group and mixed plaque group was significantly higher than in the hard plaque group (P < 0.01), but there was no statistical difference between the soft plaque group and mixed plaque group (P = 0.246). There was a negative correlation between the CT scale and Hs-CRP and IL-6 levels in the soft plaque group (r = -0.621, P < 0.01, and r = -0.593, P < 0.01 respectively). There was a positive correlation between the plaque burden and Hs-CRP and IL-6 levels in the soft plaque group (r = 0.579, P < 0.05 and r = 0.429, P < 0.05 respectively). CONCLUSIONS 64-SCTA is an effective way to distinguish the different quality of coronary atherosclerosis plaque. Serum Hs-CRP and IL-6 levels can be considered as the indexes to judge the degree of CHD and may reflect the activity of plaque in CHD patients. Thus it is important for clinical diagnosis and risk evaluation of acute coronary syndrome (ACS) patients.
The trade performance of the Middle East and North Africa

This paper characterizes the trade performance of the Middle East and North Africa (MENA) over the past 15 years. Cross-section results show that MENA's exports to the outside world were only one third of their potential in recent years, after controlling for the standard determinants of trade. Results from panel data show that MENA's exports have been expanding more rapidly than exports from the rest of the world, offering some evidence of convergence. Still, at historical growth rates, it would take 20 years for MENA countries to reach potential trade. When we exclude natural resources, exports are also only one third of the benchmark, but the improved export performance over time is much slower and implies it could take twice as long to reach potential. Interestingly, while MENA also under-trades within the region, the extent of under-trading is less acute than with the outside world. There is, however, no indication of more rapid regional integration over time, suggesting that recent trade agreements among MENA countries have not stimulated regional trade to a greater extent than external trade. Finally, the report examines intra-industry trade, which has characterized world trade growth over the period. East Asia and Europe show large and rising intra-industry trade, both globally and regionally, reflecting increased trade in differentiated goods and the expansion of supply chains. Despite neighboring these regions, the MENA countries have been largely left out of this transformation.
Evaluation of two posture survey instruments for assessing computing postures among college students.

OBJECTIVE To determine agreement between two posture assessment survey instruments and which, if any, were correlated with experiencing upper extremity musculoskeletal symptoms. METHODS Thirty undergraduate participants had three postural assessment surveys completed, one each for three separate 7-day data collection periods during a semester. Two observation assessment tools were used, a modified Rapid Upper Limb Assessment (mRULA) for computer users for the right and left limbs and the University of California Computer Use Checklist. Concurrently, upper extremity musculoskeletal symptom experience paired to each postural assessment was measured. Lin's concordance correlation coefficient evaluated survey agreement and multi-level statistical models described associations between survey responses and symptoms. RESULTS There was no agreement between the two postural assessment tool scores (p> 0.85). In adjusted models, the UC Computer Use Checklist was positively associated with symptoms occurrence (OR=1.4, 90% CI 1.2-1.6 for any symptoms; OR=1.3, 90% CI 1.0-1.6 for moderate or greater symptoms). Associations with mRULA scores were inconsistent in that they were sometimes protective and sometimes indicators of risk, depending on the covariates included in the models. CONCLUSION The mRULA for computer users and the UC Computer Use Checklist were independent of each other; however, due to the inconsistent associations with symptoms we cannot conclude one instrument is superior to the other. Our data do suggest the UC Computer Use Checklist demonstrates a traditional relationship with symptoms, where increasing scores signifiy greater risk. We observed a nontraditional relatioship with symptoms for the mRULA for computer users that needs to be further examined. This is a pilot study and, thus, findings should be interpreted as exploratory. Associations observed in the current study will be used to test hypotheses in the cohort study recently conducted.
Blinded by Growth

Everybody loves a growth story. But that does not make growth by itself a good investment thesis. Fast‐growing countries and their companies often produce low returns for investors, and slow‐growing ones sometimes produce high returns. In exploring this apparent paradox, this article argues that valuation plays a critical role. It matters not only how fast a country or company may grow, but also how much investors pay for that growth. Blinded by growth, investors often pay too much to participate in the prospective growth of both countries and companies; and as result, they earn low returns. This tendency to overpay for growth helps explain what the author describes as indisputable evidence that, over the long term, value investing beats growth investing. This article discusses growth from three different points of view. First, it looks into the relationship between general economic growth and equity returns. Second, it examines the relationship between corporate growth and equity returns. And finally, it compares value investing with growth investing.
Public Sector Support for Sport Tourism Events: The Role of Cost-benefit Analysis

Economic analysis is important in assessing the impacts and net benefits of sport tourism. The economic impacts of sporting events include the contribution to employment and income, both nationally and regionally. Sport tourism is also regarded as associated with a range of other benefits (and costs) of a more ‘intangible’ nature that impact on local communities as well as on entire regions. This study provides an overview of the framework of event impact assessment, distinguishing between a ‘narrower’ and ‘wider’ set of economic impacts and also ‘intangible’ impacts. It then explores the role of cost benefit analysis in the public support of special events.
Effect of a 12-week yoga therapy program on mental health status in elderly women inmates of a hospice

Aim and Objectives: This study was undertaken to evaluate the effectiveness of yoga on the mental health status of elderly women inmates residing in a hospice in Puducherry. Materials and Methods: Forty elderly women were randomly divided into yoga and wait-listed control group. A yoga therapy program of 60 min was given twice a week for 12 weeks. This protocol was specially designed for senior citizens, keeping in mind their health status and physical limitations that included simple warm-up and breath-body movement coordination practices (jathis and kriyas), static stretching postures (asanas), breathing techniques (pranayamas), and relaxation. Hamilton anxiety scale for measuring anxiety, Hamilton rating scale for depression, and Rosenberg self-esteem scale to measure self-esteem were administered to both groups before and after the 12-week study period. Data were assessed for normality, and appropriate parametric and nonparametric statistical methods were applied for intra- and inter-group comparisons. Results: Overall, intra- and inter-group comparison of prepost data showed statistically significant (P < 0.001) differences for all three parameters. There was an overall improvement in the scores indicating decreased levels of depression and anxiety coupled with an increase in the level of self-esteem after the yoga therapy program. Discussion: The influence of yoga in the reduction of depression and anxiety scores and improvement in self-esteem scores in elderly women subjects is evident from this study. As reported in earlier studies, this may be attributed to changes in central neurotransmitters such as gamma-aminobutyric-acid coupled with increased parasympathetic tone and decreased sympatho-adrenal activity. Conclusion: It is recommended that yoga should be a part of health-care facilities for elderly as it can enhance the quality of life by improving their overall mental health status. It could provide a healthy and positive alternative from depressing negative thoughts, and give them a sense of purpose and hope.
Evaluating the mechanical properties of E-Glass fiber/carbon fiber reinforced interpenetrating polymer networks

A series of vinyl ester and polyurethane interpenetrating polymer networks were prepared by changing the component ratios of VER (Vinyl ester) and PU (Polyurethane) and the polymerization process was confirmed with Fourier Transform infrared spectroscopy. IPN (Inter Penetrating Polymer Network - VER/PU) reinforced Glass and carbon fiber composite laminates were made using the Hand lay up technique. The Mechanical properties of the E-glass and carbon fiber specimens were compared from tests including Tensile, Compressive, Flexural, ILSS (Inter Laminar Shear Strength), Impact & Head Deflection Test (HDT). The IPN Reinforced Carbon fiber specimen showed better results in all the tests than E-Glass fibre reinforced IPN laminate with same thickness of the specimen, according to ASTM standards. It was found that the combination of 60%VER and 40%PU IPN exhibits better impact strength and maximum elongation at break, but at the slight expense of mechanical properties such as tensile, compressive, flexural, ILSS properties. The morphology of the unreinforced and reinforced composites was analyzed with help of scanning electron microscopy.
A major QTL on mouse chromosome 17 resulting in lifespan variability in SOD1-G93A transgenic mouse models of amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis is a late-onset degenerative disease affecting motor neurons in the spinal cord, brainstem, and motor cortex. There is great variation in the expression of ALS symptoms even between siblings who both carry the same Cu/Zn superoxide dismutase (SOD1) mutations. One important use of transgenic mouse models of SOD1-ALS is the study of genetic influences on ALS severity. We utilized multiple inbred mouse strains containing the SOD1-G93A transgene to demonstrate a major quantitative trait locus (QTL) on mouse chromosome 17 resulting in a significant shift in lifespan. Reciprocal crosses between long- and short-lived strains identified critical regions, and we have narrowed the area for potential genetic modifier(s) to < 2Mb of the genome. Results showed that resequencing of this region resulted in 28 candidate genes with potentially functional differences between strains. In conclusion, these studies provide the first major modifier locus affecting lifespan in this model of FALS and, once identified, these candidate modifier genes may provide insight into modifiers of human disease and, most importantly, define new targets for the development of therapies.
The Composition of Sovereign Debt: A Description

Who has access to cheaper forms of borrowing: AAA-rated US corporations or developing countries? In contrast to all expectations, data from the World Bank suggests that the average spread on all forms of borrowing by developing countries is smaller than for top-rated US corporate bonds. Part of this phenomenon is due to official lending, which is extremely cheap, but even average private lending spreads are near or below zero. The paper documents these facts (with particukar care for resolving various data problems), and then looks behind the averages. Once identifying various sub-types of borrowing, I find that official and other private lending (trade-related, or at least more firm-level lending) are the main source of the surprisingly low average spreads: these two types of lending react very little to movements in international interest rates, which - together with a not sufficiently large constant term - makes these types of loans very cheap. This also gives an "interest rate smoohing" result for official and other private lending. Bond and commercial bank lending shows reasonable spreads, and both move nearly one in one with world interest rates. All types of private lending significantly differ from each other in the way they incorporate country-specific or worldwide economic conditions. Moreover, low-income countries actively change their disbursement portfolio in response to world interest rates, which leads to "interest rate smoothing" of commercial bank lending rates as well.
Real-Time Approach to Flow Cell Imaging of Candida albicans Biofilm Development

The ability of Candida albicans to form biofilms is a virulence factor that allows tissue attachment and subsequent infection of host tissues. Fungal biofilms have been particularly well studied, however the vast majority of these studies have been conducted under static conditions. Oral biofilms form in the presence of salivary flow, therefore we developed a novel flow system used for real-time imaging of fungal biofilm development. C. albicans wild-type (WT) cells readily attached to the substrate surface during the 2 h attachment phase, then formed heterogeneous biofilms after 18 h flow. Quantitative values for biomass, rates of attachment and detachment, and cell–cell adhesion events were obtained for C. albicans WT cells and for a hyperfilamentous mutant Δhog1. Attachment rates of C. albicans WT cells were nearly 2-fold higher than C. albicans Δhog1 cells, although Δhog1 cells formed 4-fold higher biomass. The reduced normalized detachment rate was the primary factor responsible for the increased biomass of Δhog1 biofilm, showing that cell detachment rates are an important predictor for ultimate biofilm mass under flow. Unlike static biofilms, C. albicans cells under constant laminar flow undergo continuous detachment and seeding that may be more representative of the development of in vivo biofilms.
Pricing response to entry and agglomeration effects

In contrast to the traditional approach that typically views entry solely as a threat, we argue that our understanding of this important phenomenon will remain incomplete until we consider the possibility that entry may also provide opportunity for incumbent firms. Drawing from agglomeration theory, which describes the benefit from colocating with competitors, we explicitly examine the combined impact of the competitive and agglomeration effects of entry using a unique dataset of Texas hotels. We find that incumbent establishments price higher when facing entrants whose agglomeration benefits are more likely to outweigh their competitive effects. This association is stronger for incumbents that have greater experience with entry. Our results bring a new perspective to the entry response literature helping clarify inconsistent empirical results. Further, we apply agglomeration theory to a new question, incumbent behavior, and demonstrate that experience appears to play an important role in recognizing situations that generate agglomeration externalities. Copyright © 2009 John Wiley & Sons, Ltd.
Explaining Legislative Leadership Influence

Why are the leaders in some U.S.-style legislatures more influential than others? This study uses individual-level data on lawmakers’ perceptions of their leaders’ influence to test three general theories of legislative power delegation: legislative leaders have no real power, simple collective action theory, and Conditional Party Government theory. These perceptions of speakers’ legislative influence are modeled with varying intercept, multilevel, ordered probit models. The analyses strongly support the simple collective action problem explanation of legislative leadership influence, in particular suggesting that collective problems caused by the internal dynamics of the legislative process drive the delegation of influence to leaders.
Sex differences in posttraumatic stress disorder.

BACKGROUND Epidemiologic surveys in the general population documented a higher rate of posttraumatic stress disorder (PTSD) in women than in men. To date, the finding has received little scientific attention. This study examines the extent to which sex differences in PTSD might be explained by previously identified risk factors and whether the sex difference in PTSD varied by age at exposure to traumatic events. METHODS The NIMH-DIS (NIMH Diagnostic Interview Schedule, Version III Revised) was used to measure DSM-IIIR disorders in a random sample of 1007 young adults. Cox proportional hazards models were used to estimate changes in the hazards ratio for PTSD associated with sex when potential risk factors were included. RESULTS Lifetime prevalence of exposure to traumatic events and number of traumatic events did not vary by sex. The prevalence of PTSD was higher for women than for men exposed to traumatic events (hazards ratio, 2.3; 95% confidence interval, 1.5-3.6). Preexisting anxiety disorders or major depressive disorders played a part in the observed sex difference in PTSD. Family history of anxiety disorder and early separation from parents, although significant risk factors for PTSD in subjects of both sexes, were unrelated to the sex difference in PTSD. The sex difference in PTSD was markedly greater if exposure occurred in childhood than later on. CONCLUSIONS Posttraumatic stress disorder is more likely to develop in females than in males after exposure to a traumatic event. Susceptibility to PTSD in females might be greater in childhood than after age 15 years. Explanations of the sex difference might involve characteristics of individuals and of the traumatic experiences.
Advances in Credit Risk Modelling and Corporate Bankruptcy Prediction

The field of credit risk and corporate bankruptcy prediction has gained considerable momentum following the collapse of many large corporations around the world, and more recently through the sub-prime scandal in the United States. This book provides a thorough compendium of the different modelling approaches available in the field, including several new techniques that extend the horizons of future research and practice. Topics covered include probit models (in particular bivariate probit modelling), advanced logistic regression models (in particular mixed logit, nested logit and latent class models), survival analysis models, non-parametric techniques (particularly neural networks and recursive partitioning models), structural models and reduced form (intensity) modelling. Models and techniques are illustrated with empirical examples and are accompanied by a careful explanation of model derivation issues. This practical and empirically-based approach makes the book an ideal resource for all those concerned with credit risk and corporate bankruptcy, including academics, practitioners and regulators.
Doping in Sport and Competition Design

We develop a game-theoretic model of doping which focuses on the economic aspects of competitive sports. According to the model, incentives for athletes to use doping increase when (i) the efficiency of the drug test system is low, (ii) the number of competitions during one season is high, (iii) the spread of prizes from sports events is large, (iv) the perceived health cost is low. Implications for anti-doping policy are derived. We also discuss the optimal (anti-doping) competition design.
Household Level Financial Incentives to Adoption of Conservation Agricultural Technologies in Africa

Although several studies have been conducted to determine the viability of conservation agriculture in Sub-Saharan Africa, almost all such studies are fragmented – often country specific – and with undue emphasis on output effects. However, assessment of the attractiveness of these technologies in Sub-Saharan Africa requires a detailed case-by-case comparison of changes in output and input costs and benefits. This paper reviews a set of responses known collectively as “conservation” or “sustainable” agriculture. Though definitions vary, these technologies typically involve agricultural management practices that prevent degradation of soil and water resources and thereby permit sustainable farm productivity without environmental degradation.
Exploring soft versus hard factors for TQM implementation in small and medium‐sized enterprises

Purpose – This paper aims to rank the emphasis placed on critical factors and quality management principles that determine the success of total quality management (TQM) as it applies to quality management system implementation in small and medium‐sized enterprises (SMEs). Design/methodology/approach – This paper is a synthesis of the literature on TQM implementation in SMEs operating in a developing environment and identifies critical factors. These factors are prioritised according to the frequency in which they appeared by number of articles. The compliance requirements of the ISO 9001:2000 standard is mapped to one or a combination of quality management principles (QMPs) on which the standard is based. These principles are grouped as soft and hard and ranked in terms of the number of compliance requirements they represent.Findings – The paper identifies critical factors of TQM implementation for SMEs operating in a developing economy. Although exploratory in nature, evidence shows that, while researcher.
Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution

An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.