Miracle-dz/UniFAR-FTUs huggingface dataset:
Nondestructive inspection of phase transformation in zirconia-containing hip joints by confocal Raman spectroscopy

Abstract. Environmental metastability of zirconia (ZrO2) ceramic in the human body [represented by a tetragonal-to-monoclinic (t→m) phase transformation] takes place on the surface of the artificial joint and proceeds with time toward its interior. Its quantitative characterization is mandatory for the safety of joint implants and consists of the assessment of the in-depth monoclinic profile fraction as compared to that of the initially untransformed material. We attempt to fully establish a characterization protocol and present two different nondestructive approaches for resolving highly graded phase-transformation profiles along the hip-joint subsurface by confocal Raman microprobe technique. A series of partially transformed tetragonal zirconia polycrystal and zirconia-toughened alumina ceramics are used as screening samples. Probe biases could be eliminated and the real transformation profiles retrieved through a deconvolution procedure of Raman experimental data collected as a function of pinhole aperture and focal depth, respectively. Confirmation of the confocal assessments was made by a destructive cross-sectional inspection by both laser optical microscope and Raman spectral line scans. This study unveils for the first time the real quantitative amount of surface phase-transformation fractions and the related subsurface profiles in zirconia-based retrieved medical samples.
Constraining the rate of GRB visible afterglows with the CFHTLS very wide survey

Aims. We analyze images of the CFHTLS Very Wide Survey to search for visible orphan afterglows from gamma-ray bursts (GRBs). Methods. We have searched 490 square degrees down to magnitude r' = 22.5 for visible transients similar to GRB afterglows. We translate our observations into constraints on the number of GRB visible afterglows in the sky, by measuring the detection efficiency of our search with a simulation reproducing the characteristics of our observational strategy and the properties of on-axis GRB afterglows. Results. We have found only three potential candidates, of which two are most probably variable stars, and one presents similarities to an orphan afterglow. We constrain the number of visible afterglows to be less than 220 down to r' = 22.5 in the whole sky at any time. Our observations are marginally consistent with the most optimistic model, which predicts orphan afterglows to be about 10 times more frequent than GRBs. Conclusions. This search has led to the detection of one possible GRB afterglow, and provides the strongest constraints on the rate of GRB visible afterglows as well as an estimation of the observing time required to detect a significant number of GRB afterglows.
Intellectual Development in Adulthood: The Seattle Longitudinal Study

1. Introduction 2. Methodological issues 3. The data base 4. Cross sectional studies 5. Longitudinal studies 6. Studies of cohort and period differences 7. Intervention studies 8. Methodological studies 9. The relationship between cognitive styles and intellectual functioning 10. Health and maintenance of intellectual functioning 11. Life style variables that affect intellectual functioning 12. The longitudinal study of personality traits and attitudes 13. Family studies of intellectual abilities in adulthood 14. Subjective perceptions of cognitive change 15. Summary and conclusions.
LEXICAL COHESION IN SONG LYRIC PERRY’S FIREWORK

Penelitian ini berjudul “Bahasa kiasan dalam lyric lagu firework perry”. Topik terpilih karena bahasa kiasan yg digunakan dalam banyak cerita dan bnayak lagu dan kemudian terpilih lagu karena lagu yg berisi dengan banyak bahasa kiasan. Data penelitian ini diambil dari download di internet. Dan kemudian membaca serta menelaah lirik lagu yang dipilihdengan focus mengidentisifikasilagu tersebut. Setelah itu mengklasifikasikan bahasa kiasan yang ditemukan dalam lirik. Data yang terkumpul dianalisis dengan menggunakan teori Knickerbocker untuk menemukan jenis bahasa kiasan tersebut, apakah itu ironi, hiperbola atau personifikasi dan setelah itu, dan yang terakhir, mencoba menafsirkan maksud dari penulis didasarkan pada teori Leech.
Design of indomethacin-loaded nanoparticles: effect of polymer matrix and surfactant

Despite recent advances in nonsteroidal anti-inflammatory drug (NSAID) formulations, the design of targeted delivery systems to improve the efficacy and reduce side effects of NSAIDs continues to be a focus of much research. Enteric nanoparticles have been recognized as a potential system to reduce gastrointestinal irritations caused by NSAIDs. The aim of this study was to evaluate the effect of EUDRAGIT® L100, polyethylene glycol, and polysorbate 80 on encapsulation efficiency of indomethacin within enteric nanoparticles. Formulations were developed based on a multilevel factorial design (three factors, two levels). The amount of polyethylene glycol was shown to be the factor that had the greatest influence on the encapsulation efficiency (evaluated response) at 95% confidence level. Some properties of nanoparticles like process yield, drug–polymer interaction, particle morphology, and in vitro dissolution profile, which could affect biological performance, have also been evaluated.
SURVEI TINGKAT KEBUGARAN JASMANI DENGAN MENGGUNAKAN TES KEBUGARAN JASMANI INDONESIA PADA SISWA SEKOLAH DASAR

Abstrak: Tujuan penelitian adalah untuk mengetahui tingkat kebugaran jasmani siswa kelas VI Sekolah Dasar Negeri 36 Sungai Raya Kabupaten Kubu Raya. Metode yang digunakan dalam penelitian ini adalah metode deskriptif serta menggunakan instrumen Tes Kebugaran Jasmani Indonesia (TKJI) kelompok anak umur 10-12 tahun. Populasi dalam penelitian ini adalah seluruh siswa Sekolah Dasar Negeri 36 Sungai Raya Kabupaten Kubu Raya. Sampel penelitian ini adalah 20 siswa (15 putera dan 5 puteri). Hasil penelitian tersebut dengan menggunakan perhitungan deskriptif persentase bahwa tingkat kebugaran jasmani siswa VI Sekolah Dasar Negeri 36 Sungai Raya Kabupaten Kubu Raya tahun 2014 untuk putera sebagian sebesar memiliki kriteria sedang yaitu 47%, sedangkan untuk puteri memiliki kriteria kurang yaitu 40%. Disimpulkan hasilnya adalah tingkat kebugaran jasmani pada siswa kategori baik. Kata Kunci : Kebugaran jasmani, Tes Kebugaran Jasmani Indonesia Abstract: The purpose of the study was to assess the physical fitness of students of class VI Public Elementary School 36 Sungai Raya, Kubu Raya district. The method used in this research is descriptive method and the use of instruments Indonesian Physical Fitness Test (TKJI) group of 10-12 year olds. The population in this study were all students of State Elementary School 36 Sungai Raya, Kubu Raya district. The sample was 20 students (15 sons and 5 daughters) The results of the study using descriptive calculation of the percentage of students that physical fitness level VI Public Elementary School 36 Sungai Raya, Kubu Raya district 2014 to the son of the majority of the criteria was 47%, while to have a daughter that is 40% less criteria. Summed result is the level of physical fitness in students either category. Keywords: Physical Fitness, Physical Fitness Tests Indonesia
Differential Privacy and Machine Learning: a Survey and Review

The objective of machine learning is to extract useful information from data, while privacy is preserved by concealing information. Thus it seems hard to reconcile these competing interests. However, they frequently must be balanced when mining sensitive data. For example, medical research represents an important application where it is necessary both to extract useful information and protect patient privacy. One way to resolve the conflict is to extract general characteristics of whole populations without disclosing the private information of individuals. In this paper, we consider differential privacy, one of the most popular and powerful definitions of privacy. We explore the interplay between machine learning and differential privacy, namely privacy-preserving machine learning algorithms and learning-based data release mechanisms. We also describe some theoretical results that address what can be learned differentially privately and upper bounds of loss functions for differentially private algorithms. Finally, we present some open questions, including how to incorporate public data, how to deal with missing data in private datasets, and whether, as the number of observed samples grows arbitrarily large, differentially private machine learning algorithms can be achieved at no cost to utility as compared to corresponding non-differentially private algorithms.
Regulation of Aldo–Keto Reductases in Human Diseases

The aldo–keto reductases (AKRs) are a superfamily of NAD(P)H-linked oxidoreductases, which reduce aldehydes and ketones to their respective primary and secondary alcohols. AKR enzymes are increasingly being recognized to play an important role in the transformation and detoxification of aldehydes and ketones generated during drug detoxification and xenobiotic metabolism. Many transcription factors have been identified to regulate the expression of human AKR genes, which could have profound effects on the metabolism of endogenous mediators and detoxication of chemical carcinogens. This review summarizes the current knowledge on AKR regulation by transcription factors and other mediators in human diseases.
The immunomodulatory effects induced by dietary Zearalenone in pregnant rats

Abstract Context: Zearalenone (ZEN) is a common contaminant that is present in feedstuff of high humidity and high temperatures. Objective: The aim of this study was to investigate the effects of diets contaminated with different concentrations of ZEN on immunomodulation in early pregnant rats. Materials and methods: Forty-eight pregnant Sprague Dawley (SD) rats were randomly divided into four treatment groups fed on a diet supplemented with one of four concentrations of ZEN: 0 mg/kg (ZEN 0), 50 mg/kg (ZEN 50), 100 mg/kg (ZEN 100) and 150 mg/kg (ZEN 150). The pregnant rats were fed ZEN-treated diets from gestation days 0 to 7 and a basal diet from gestation days 8 to 20. Results: ZEN exposure (ZEN 100 and 150) caused significant decreases in splenic coefficients, viability of splenocyte and T-cell proliferation and induced histopathological damage in the spleen of early pregnant rats compared with other groups. Levels of IgG and IgA were decreased, while IgM was increased, in high doses of ZEN (ZEN 100 and ZEN 150) compared with other groups. ZEN 150 caused increases in white blood cells and hemoglobin and induced a significant decrease in platelets in blood of the pregnant rats compared with other groups. ZEN 150 increased the mRNA expression levels of interleukin (IL)-6, IL-18 and IL-1β and decreased the mRNA expression levels of interferon-γ, tumor necrosis factor-α and IL-10 in the spleen of pregnant rats compared with ZEN 0. Conclusion: High doses of ZEN-induced immunomodulatory effects on early pregnant rats by altering immunological parameters.
Low grade squamous intraepithelial lesion, epithelial cell abnormality‐adjusted workload, and the thinprep imaging system

Previous studies have shown a negative correlation between screening sensitivity using the ThinPrep Imaging System (TIS) and epithelial cell abnormality (ECA) adjusted workload (ECA rate × actual slides screened/day) at the thresholds of atypical squamous cells of undetermined significance (ASCUS) and high‐grade squamous intraepithelial lesion (HSIL). We sought to determine if a similar correlation could be shown at the threshold of low grade squamous intraepithelial lesion (LSIL). Using data in seven manuscripts from the literature that contain sufficient information, the change in screening sensitivity using the TIS compared with manual screening was negatively correlated with ECA adjusted workload (y = −3.75x + 54, R2 = 0.104). Using the sensitivity of manual screening of 79% for manual screening at a threshold of LSIL from the original TIS trial, 100% sensitivity could be achieved at an ECA adjusted workload of approximately seven slides/day, the same workload that achieves 100% sensitivity at a threshold of ASCUS and slightly higher than the threshold for HSIL. We conclude that the ECA adjusted workload is a valuable method to assess workload for the TIS at the threshold of LSIL. Laboratories using the TIS should restrict workload to seven ECA adjusted slides/day (maximum actual slides/day = 700/ECA percentage). Diagn. Cytopathol. 2012. © 2010 Wiley Periodicals, Inc.
Comparative Anatomy of Mouse and Human Nail Units

Recent studies of mice with hair defects have resulted in major contributions to the understanding of hair disorders. To use mouse models as a tool to study nail diseases, a basic understanding of the similarities and differences between the human and mouse nail unit is required. In this study we compare the human and mouse nail unit at the macroscopic and microscopic level and use immunohistochemistry to determine the keratin expression patterns in the mouse nail unit. Both species have a proximal nail fold, cuticle, nail matrix, nail bed, nail plate, and hyponychium. Distinguishing features are the shape of the nail and the presence of an extended hyponychium in the mouse. Expression patterns of most keratins are similar. These findings indicate that the mouse nail unit shares major characteristics with the human nail unit and overall represents a very similar structure, useful for the investigation of nail diseases and nail biology. Anat Rec, 296:521–532, 2013. © 2013 Wiley Periodicals, Inc.
Hypoglycaemia and predisposing factors among clinical subgroups treated with intensive insulin therapy

In previous studies, conflicting intensive insulin therapy (IIT) results have been observed, whereby IIT‐related mortality seems to be lower in specific clinical subgroups. The aim of this study was to assess differences in glycaemic control, the risk of critical hypoglycaemia (≤ 2.2 mmol/l), the associated predisposing factors, and the in‐hospital mortality in different clinical subgroups treated with IIT.
Advances in Social Network Analysis: Research in the Social and Behavioral Sciences

Introduction - Joseph Galaskiewicz and Stanley Wasserman Advances in the Social and Behavioral Sciences from Social Network Analysis PART ONE: SOCIAL PSYCHOLOGY AND DIFFUSION Network Studies of Social Influence - Peter V Marsden and Noah E Friedkin Epidemiology and Social Networks - Martina Morris Modeling Structured Diffusion Statistical Models for Social Support Networks - Michael E Walker, Stanley Wasserman and Barry Wellman Social Cognition in Context - Philippa Pattison Some Applications of Social Network Analysis PART TWO: ANTHROPOLOGY AND COMMUNICATION Anthropological Contributions to the Study of Social Networks - Jeffrey C Johnson A Review Primate Social Networks - Donald Stone Sade and Malcolm M Dow Network Analysis and Computer-Mediated Communication Systems - Ronald E Rice PART THREE: POLITICS AND ORGANIZATIONS Intraorganizational Networks - David Krackhardt and Daniel J Brass The Micro Side Networks of Interorganizational Relations - Mark S Mizruchi and Joseph Galaskiewicz Marketing and Social Networks - Phipps Arabie and Yoram Wind Networks of Elite Structure and Decision Making - David Knoke
Stress reactivity in borderline personality disorder

• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Analysis of Al-Qaeda Terrorist Attacks to Investigate Rational Action

Many studies have been conducted to demonstrate the collective rationality of traditional terrorist groups; this study seeks to expand this and apply collective rationality to Islamic terrorist groups. A series of statistical analyses were conducted on terrorist attacks carried out by Al-Qaeda and affiliated terrorist organization; these were then compared to two more conventional terrorist groups: the Euskadi Ta Askatasuna (ETA) and the Liberation Tigers of Tamil Eelam (LTTE). When viewed through the context of the groups’ various motivations and objectives, the results of these analyses demonstrates collective rationality for those terrorist groups examined.
Staff induction practices and organizational socialization: A review and extension of the debate

Purpose – Socialization is one of the fundamental processes that define how collectivities emerge. Socialization underpins the social structures that shape not only how social actors interact in community but also the boundaries of action and the rules of engagement. In the context of organizations, socialization is a process that significantly shapes organization in the way core practices shape how things are done and why they are done in particular ways. This emphasis on consistency within and between practices is seen to be greatly facilitated by specific practices like staff induction. The purpose of this paper is to review the current conceptual and empirical research on staff induction as a process of organizational socialization and outlines some of the areas for future research particularly if a social practice perspective is adopted.Design/methodology/approach – The paper presents a systematic review of the relevant literature on organizational socialization and staff induction and outlines theme.
Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes

A subgroup of colorectal cancer (CRC) shows non‐random accumulation of aberrant DNA methylation, so‐called CpG island methylator phenotype (CIMP), which was associated with microsatellite instability and BRAF mutation. As just one group of methylation markers was suitable to extract CIMP+/CIMP‐high, and had been commonly used in the “one‐panel method”, it had been unclear whether another cluster of CRC with DNA methylation accumulation exists in microsatellite‐stable CRC. We therefore epigenotyped CRC by a comprehensive approach, that is, the two‐way unsupervised hierarchical clustering method using highly quantitative methylation data by a single detection method, MALDI‐TOF mass spectrometry, on novel regions selected genome‐widely through methylated DNA immunoprecipitation on array analysis. CRC was clearly clustered into three DNA methylation epigenotypes, high‐, intermediate‐ and low‐methylation epigenotypes (HME, IME, and LME, respectively). Methylation markers are clustered into two distinct groups: Group‐1 methylated specifically in HME and including most reported CIMP‐related markers; and Group‐2 methylated both in HME and IME. While suitable markers to detect a subgroup of CRC with intermediate methylation and correlation to KRAS mutation have been expected to be developed, our data indicated that a “two‐panel method” is necessary to properly classify CRC into three epigenotypes, the first panel to extract HME using Group‐1 markers, and the second panel to divide the remaining into IME and LME using Group‐2 markers. Here we review and compare our recent study and reported CRC classification methods by DNA methylation information, and propose the use of two panels of methylation markers as CRC classifiers. (Cancer Sci 2011; 102: 18–24)
Stable small quantum dots for synaptic receptor tracking on live neurons.

We developed a coating method to produce functionalized small quantum dots (sQDs), about 9 nm in diameter, that were stable for over a month. We made sQDs in four emission wavelengths, from 527 to 655 nm and with different functional groups. AMPA receptors on live neurons were labeled with sQDs and postsynaptic density proteins were visualized with super-resolution microscopy. Their diffusion behavior indicates that sQDs access the synaptic clefts significantly more often than commercial QDs.
Gouvernance familiale et politique de distribution aux actionnaires

(VF)L’objectif de cette etude est d’analyser la relation entre les politiques de distribution des entreprises familiales cotees et deux grands types de conflits d’agence dans les entreprises familiales, entre actionnaires et dirigeant (type I), et entre actionnaires majoritaires et minoritaires (type II). Les resultats sur les entreprises du SBF 250 montrent que les montants distribues sont lies a ces deux composantes du conflit d’agence, qui est globalement moins fort dans les entreprises familiales. (VA)This paper studies payout policies of listed family firms. The recent evolution of family firm models allows for a study of two types of agency conflicts, the one between shareholders and the manager (type I), and the one between majority and minority shareholders (type II). Our results show that payout policies are related to the intensity of the two types of agency conflicts which are overall weaker than in non family firms.
Coherent Functions in Autonomous Systems

A fuzzy controller can be seen as an algorithm that, given a fuzzy set (input) and a set of linguistic rules, computes the degree of possibility of every control value. Using a valid and complete proof system for possibilistic logic, we will prove that fuzzy controllers enjoy the following property: every possibility measure that satisfies the degrees of possibility of the input and of the linguistic rules also satisfies, for every control value, the degree of possibility computed by the fuzzy controller. We will call such property the coherence between input, task description and output. A general definition of coherent function is given, and we will see that coherent functions form a class of functions that properly contains fuzzy controllers. Moreover, we will present an application of coherent functions to a task different from control, namely localization in mobile robotics.
Assortment Optimization under the Multinomial Logit Model with Random Choice Parameters

We consider assortment optimization problems under the multinomial logit model, where the parameters of the choice model are random. The randomness in the choice model parameters is motivated by the fact that there are multiple customer segments, each with different preferences for the products, and the segment of each customer is unknown to the firm when the customer makes a purchase. This choice model is also called the mixture‐of‐logits model. The goal of the firm is to choose an assortment of products to offer that maximizes the expected revenue per customer, across all customer segments. We establish that the problem is NP complete even when there are just two customer segments. Motivated by this complexity result, we focus on assortments consisting of products with the highest revenues, which we refer to as revenue‐ordered assortments. We identify specially structured cases of the problem where revenue‐ordered assortments are optimal. When the randomness in the choice model parameters does not follow a special structure, we derive tight approximation guarantees for revenue‐ordered assortments. We extend our model to the multi‐period capacity allocation problem, and prove that, when restricted to the revenue‐ordered assortments, the mixture‐of‐logits model possesses the nesting‐by‐fare‐order property. This result implies that revenue‐ordered assortments can be incorporated into existing revenue management systems through nested protection levels. Numerical experiments show that revenue‐ordered assortments perform remarkably well, generally yielding profits that are within a fraction of a percent of the optimal.