Miracle-dz/UniFAR-FTUs huggingface dataset:
Adverse Health Effects and Unhealthy Behaviors among Medical Students Using Facebook

Little is known about the relationships between adverse health effects and unhealthy behaviors among medical students using Facebook. The aim of this study was to determine the associations between adverse health effects and unhealthy behaviors with Facebook use. A cross-sectional study was conducted in a private university in Malaysia among 316 medical students. A self-administered questionnaire was used. It included questions on sociodemographics, pattern of Facebook use, social relationship, unhealthy behaviors, and health effects. Mean age was 20.5 (±2.7) years. All students had a Facebook account. The average daily Facebook surfing hours were 2.5 (±1.7). Significant associations were found between average hours of Facebook surfing and the following factors: isolation from family members and community, refusing to answer calls, musculoskeletal pain, headache, and eye irritation (P < 0.005). The average hours spent on Facebook were significantly associated with holding urination and defecation while online, surfing Facebook until midnight, and postponing, forgetting, or skipping meals (P < 0.005). The average hours spent on Facebook were associated with adverse health effects and unhealthy behaviors among medical students, as well as social isolation from the family and community.
Transbilayer and interbilayer phospholipid exchange in dimyristoylphosphatidylcholine/dimyristoylphosphatidylethanolamine large unilamellar vesicles.

The rates of spontaneous interbilayer and transbilayer exchange of [3H]dimyristoylphosphatidylcholine ([3H]DMPC) were examined in DMPC and DMPC/dimyristoylphosphatidylethanolamine (DMPE) large unilamellar vesicles in the liquid-crystalline-, gel-, and mixed-phase states. DMPC desorption rates from either gel or liquid-crystalline phases containing DMPE are very similar to the corresponding rates from pure DMPC gel or liquid-crystalline phases. This is not the case for DMPC desorption from distearoylphosphatidylcholine (DSPC)-containing gel phases, where the desorption rates are significantly faster than from a pure DMPC gel phase [Wimley, W. C. , & Thompson, T. E. (1990) Biochemistry 29, 1296-1303]. We proposed that the DMPC/DSPC behavior results from packing defects in gel phases composed of both DMPC and DSPC molecules because of the four-carbon difference in the acyl chain lengths of the two species. The present results strongly support this hypothesis because no such anomalous behavior is observed in DMPC/DMPE, which is similar to DMPC/DSPC in phase behavior but does not have the chain length difference. The inclusion of 10-30 mol % DMPE in DMPC bilayers was also found to have a significant effect on the rate of transbilayer movement (flip-flop) of [3H]DMPC in the liquid-crystalline phase. Between 10 and 30 mol % DMPE, flip-flop of DMPC is slowed by at least 10-fold relative to flip-flop in DMPC bilayers, and the entropy and enthalpy of flip-flop activation are both substantially decreased. (ABSTRACT TRUNCATED AT 250 WORDS)
Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition.

OBJECTIVE Results of previous studies suggest that memory complaints may predict cognitive decline and dementia among elderly people in whom cognitive impairment is already apparent. However, cognitive decline is often a gradual process, and elderly people may notice that their memory deteriorates before mental status tests are able to detect any change in cognitive functioning. Therefore, the authors hypothesized that memory complaints would predict incident Alzheimer's disease in elderly subjects with no signs of cognitive impairment. METHOD In the community-based Amsterdam Study of the Elderly, a sample of 3,778 nondemented persons, 65 to 84 years old, was selected and divided into two cognitive categories: normal (Mini-Mental State scores of 26-30) and borderline and impaired (Mini-Mental State scores less than 26). At baseline, the presence or absence of memory complaints was assessed. At follow-up, incident cases of Alzheimer's disease were diagnosed in a two-step procedure. RESULTS After an average of 3.2 years, 2,169 persons were reevaluated, of whom 77 had incident Alzheimer's disease. Multivariate logistic regression analyses showed that memory complaints were associated with incident Alzheimer's disease in subjects with normal baseline cognition but not in subjects with impaired baseline cognition. CONCLUSIONS The findings of this study suggest that memory complaints are a relatively strong predictor of incident Alzheimer's disease in older persons in whom cognitive impairment is not yet apparent. Furthermore, they suggest that older persons may be aware of a decline in cognition at a time when mental status tests are still unable to detect a decline from premorbid functioning.
Empirical Model of Dynamic Merger Enforcement - Choosing Ownership Caps in U.S. Radio

The paper introduces a method to conduct a forward-looking antitrust review of horizontal mergers. The method utilizes a dynamic oligopoly model in which mergers, entry/exit, and product repositioning are endogenous. The model provides long-run industry trajectories with and without the merger under review, enabling the regulator to obtain dynamically robust welfare comparisons. The paper demonstrates the framework’s application to regulate the U.S. radio broadcasting industry. In particular, it investigates the long-run efficacy of two commonly used merger heuristics: radio station ownership caps (see the Telecom Act of 1996) and static merger simulations. The paper finds that raising the ownership cap results in higher total welfare and demonstrates varying long-run effectiveness of merger simulations. This paper was accepted by Mathew Shum, marketing. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2022. 4599 .
Qualitative Case Study Guidelines

Although widely used, the qualitative case study method is not well understood. Due to conflicting epistemological presuppositions and the complexity inherent in qualitative case-based studies, scientific rigor can be difficult to demonstrate, and any resulting findings can be difficult to justify. For that reason, this paper discusses methodological problems associated with qualitative case-based research and offers guidelines for overcoming them. Due to its nearly universal acceptance, Yin’s six-stage case study process is adopted and elaborated on. Moreover, additional principles from the wider methodological literature are integrated and explained. Finally, some modifications to the dependencies between the six case study stages are suggested. It is expected that following the guidelines presented in this paper may facilitate the collection of the most relevant data in the most efficient and effective manner, simplify the subsequent analysis, as well as enhance the validity of the resulting findings. The paper should be of interest to students (honour, masters, doctoral), academics, and practitioners involved with conducting and reviewing qualitative case-based studies.
Centralized caching in two-layer networks: Algorithms and limits

The problem of the centralized caching is studied in a two-layer network. The first layer of the network is constructed by a server and K1 helpers, and the second layer consists of K1 orthogonal sub-networks, each of which contains a helper and K2 users. The pioneer caching design in the two-layer network is to directly apply the Maddah-Ali & Niesen (MAU) centralized caching [1] into individual layers, such that single-layer multicast opportunities (SMO) are deployed. In this paper, a joint caching (JC) algorithm is developed by exploiting both the SMO and the correlations of caching contents across two layers, namely, cross-layer storage correlations (CSC). Furthermore, cross-layer multicast opportunities (CMO) can also be created by applying the MAU scheme between the server and users. In order to simultaneously obtain the caching gains from SMO, CSC, and CMO, a hybrid caching scheme is proposed and demonstrated to be order-optimal when the storage sizes at both helpers and users are limited. In other words, the achievable rate region lies within a constant multiplicative and additive gap of the information-theoretic bounds. In particular, the multiplicative and additive factors can be carefully characterized to be 1/48 and 4, respectively.
DAB2IP in cancer

DOC-2/DAB2 is a member of the disable gene family that features tumor-inhibiting activity. The DOC-2/DAB2 interactive protein, DAB2IP, is a new member of the Ras GTPase-activating protein family. It interacts directly with DAB2 and has distinct cellular functions such as modulating different signal cascades associated with cell proliferation, survival, apoptosis and metastasis. Recently, DAB2IP has been found significantly down regulated in multiple types of cancer. The aberrant alteration of DAB2IP in cancer is caused by a variety of mechanisms, including the aberrant promoter methylation, histone deacetylation, and others. Reduced expression of DAB2IP in neoplasm may indicate a poor prognosis of many malignant cancers. Moreover, DAB2IP stands for a promising direction for developing targeted therapies due to its capacity to inhibit tumor cell growth in vitro and in vivo. Here, we summarize the present understanding of the tumor suppressive role of DAB2IP in cancer progression; the mechanisms underlying the dysregulation of DAB2IP; the gene functional mechanism and the prospects of DAB2IP in the future cancer research.
Ileal digestibility of nutrients and amino acids in unfermented, fermented soybean meal and canola meal for weaning pigs.

Apparent ileal digestibility (AID) of energy, dry matter, nitrogen and amino acids and standardized ileal digestibility (SID) of nitrogen and amino acids were evaluated in six weanling pigs ((Landrace × Yorkshire) × Duroc)) fed unfermented soybean meal (SM), yeast fermented soybean meal (SMY), bacillus fermented soybean meal (SMB), yeast and bacillus fermented soybean meal (SMYB), canola meal (CM) and nitrogen-free diet. Pigs having body weights 17.00 ± 0.3 kg were surgically equipped with T-cannulas of approximately 15 cm prior to the ileo-cecal junction and randomly allotted to one of five dietary treatments and a nitrogen-free diet in 6 × 6 Latin squares. AID and SID of nitrogen (N) was greater (P < 0.05) in SMYB and SMB compared with SM and CM. AID and SID of amino acids such as, Lys (lysine) and Phe (phenylalanine) as well as total essential amino acids were greater (P < 0.05) in SMB and tended to be low in CM compared with SM. AID and SID of aspartic acid (Asp) and glycine (Gly) tended to be higher in SMB compared with SM and other diets except CM. In conclusion, fermentation of soybean meal by Bacillus showed better digestibility of amino acid and nutrients.
Mispricing of Sovereign Risk and Multiple Equilibria in the Eurozone

This paper finds evidence that a significant part of the surge in the spreads of the PIGS countries (Portugal, Ireland, Greece and Spain) in the eurozone during 2010-11 was disconnected from underlying increases in the debt-to-GDP ratios, and was the result of negative market sentiments that became very strong since the end of 2010. We also find evidence that after years of neglecting high government debt, investors became increasingly worried about this in the eurozone, and reacted by raising the spreads. No such worries developed in stand-alone countries despite the fact that debt-to-GDP ratios were equally high and increasing in these countries. We interpreted this evidence as validating the hypothesis formulated in De Grauwe (2011) according to which government bond markets in a monetary union are more fragile and more susceptible to self-fulfilling liquidity crises than in stand-alone countries. We argue that the systematic mispricing of sovereign risk in the eurozone intensifies macroeconomic instability, leading to bubbles in good years and excessive austerity in bad years.
Detecting interspecific recombination with a pruned probabilistic divergence measure

MOTIVATION A promising sliding-window method for the detection of interspecific recombination in DNA sequence alignments is based on the monitoring of changes in the posterior distribution of tree topologies with a probabilistic divergence measure. However, as the number of taxa in the alignment increases or the sliding-window size decreases, the posterior distribution becomes increasingly diffuse. This diffusion blurs the probabilistic divergence signal and adversely affects the detection accuracy. The present study investigates how this shortcoming can be redeemed with a pruning method based on post-processing clustering, using the Robinson-Foulds distance as a metric in tree topology space. RESULTS An application of the proposed scheme to three synthetic and two real-world DNA sequence alignments illustrates the amount of improvement that can be obtained with the pruning method. The study also includes a comparison with two established recombination detection methods: Recpars and the DSS (difference of sum of squares) method. AVAILABILITY Software, data and further supplementary material are available at the following website: http://www.bioss. sari.ac. uk/~dirk/Supplements/
Choice of image features for depth-axis control in image based visual servo control

This paper is concerned with choosing image features for image based visual servo control and how this choice influences the closed-loop dynamics of the system. In prior work, image features tend to be chosen on the basis of image processing simplicity and noise sensitivity. In this paper we show that the choice of feature directly influences the closed-loop dynamics in task-space. We focus on the depth axis control of a visual servo system and compare analytically various approaches that have been reported recently in the literature. The theoretical predictions axe verified by experiment.
Use of Molecular Diagnostic Tools for the Identification of Species Responsible for Snakebite in Nepal: A Pilot Study

Snakebite is an important medical emergency in rural Nepal. Correct identification of the biting species is crucial for clinicians to choose appropriate treatment and anticipate complications. This is particularly important for neurotoxic envenoming which, depending on the snake species involved, may not respond to available antivenoms. Adequate species identification tools are lacking. This study used a combination of morphological and molecular approaches (PCR-aided DNA sequencing from swabs of bite sites) to determine the contribution of venomous and non-venomous species to the snakebite burden in southern Nepal. Out of 749 patients admitted with a history of snakebite to one of three study centres, the biting species could be identified in 194 (25.9%). Out of these, 87 had been bitten by a venomous snake, most commonly the Indian spectacled cobra (Naja naja; n = 42) and the common krait (Bungarus caeruleus; n = 22). When both morphological identification and PCR/sequencing results were available, a 100% agreement was noted. The probability of a positive PCR result was significantly lower among patients who had used inadequate “first aid” measures (e.g. tourniquets or local application of remedies). This study is the first to report the use of forensic genetics methods for snake species identification in a prospective clinical study. If high diagnostic accuracy is confirmed in larger cohorts, this method will be a very useful reference diagnostic tool for epidemiological investigations and clinical studies.
Arsenic speciation in rice-based food for adults with celiac disease

Celiac disease (CD) may affect up to 1% of the Western population. It is a disease whose diagnosis has been made mainly in childhood, but now the profile has changed, with one out of five newly diagnosed individuals being over 65 years old. The only treatment for this population is a gluten-free diet. Therefore, the objective of this study was to analyse the occurrence of arsenic (As) in gluten-free products, basically those rice-based, intended for celiac adult consumers. The current study demonstrated that these rice-based products contained important contents of total arsenic (t-As) (up to 120 μg kg−1) and inorganic arsenic (i-As) (up to 85.8 μg kg−1). It was estimated that the contents of t-As and i-As in rice used as the main ingredient of these foods were as high as 235 and 198 μg kg−1, respectively. The estimated daily intake of i-As was 0.46 and 0.45 μg kg−1 bw in women and men of 58 and 75 kg of body weight (bw), respectively. These values indicate that a health risk to these consumers cannot be excluded. Finally, legislation is needed to delimit the safety intake by health agencies and to improve the labelling of these special rice-based foods for celiac adult consumers. The label should include information about percentage, geographical origin and cultivar of the rice used; besides and if companies want to clearly prove the safety of their products, the exact content of i-As should also be included. Graphical Abstract
Attitudes toward long-acting reversible contraception among young women seeking abortion.

AIMS Use of long-acting reversible contraceptive (LARC) methods can reduce rates of unplanned pregnancy and abortion, but for a range of reasons, these methods are underused by young women. A third of women seeking abortion return for a subsequent abortion during their reproductive years and could benefit from using effective long-acting methods. We aimed to explore the attitudes of women seeking abortion toward contraception, with a focus on long-acting methods. METHODS Thirty women aged 16-25 (of Maori, Pacific Island, and European ethnicities) were recruited at a public hospital abortion clinic to participate in a semistructured interview. Participants were asked about past use of contraception, their understanding of pregnancy risk, reasons for method choice; and views on long-acting methods. Qualitative data were analyzed using thematic content analysis. RESULTS There was a lack of prior knowledge about LARC methods (particularly intrauterine devices [IUD] and implants). Once information was provided, these methods were generally viewed favorably. Cost was a key factor in contraceptive choice, prohibiting choice of the Mirena® levonorgestrel intrauterine system (LNG-IUS) or an implant for many women. Other important factors that determined method use and choice were familiarity with methods, whether or not they contained hormones, likely effect on periods, and other side effects. CONCLUSIONS Access issues relating to LARC methods (including cost and awareness) need to be urgently addressed. When discussing postabortion contraceptive options, women would benefit from simple explanations about LARC: their appropriateness for women of all reproductive ages, reversible nature, mechanisms of action, impact on menstruation, and other potential side effects.
Reliability and Validity of the Implicit Association Test Measuring Shame

ii TABLE OF CONTENTS iii LIST OF FIGURES iv LIST OF TABLES v Shame and Guilt 1 Functions 2 Shame and Guilt in Psychopathology 3 Cognitive Biases 3 Avoidance 4 Abuse-Psychopathology Link 4 Measuring Shame in Research 5 Explicit Measurement 5 Explicit Processing 7 Implicit Processing 8 The Implicit Association Test 9 Benefits of the IAT-Shame 10 Empirical Benefits 10 Additional Clinical Benefits 11 Specific Aims 11 Methods 13 Research Design Overview 13 Materials 14 Explicit Self-Report Measures. 14 Implicit Measure: IAT-Shame 16 Improved Scoring Algorithm 19 Procedure 20 Results 22 Discussion 27 REFERENCES 32 APPENDICES 36 Appendix A: Demographics 36 Appendix B: ESS 37 Appendix C: TOSCA-3 40 Appendix D: BDI-II 49 Appendix E: STAI 51 Appendix G: SF-36 55 Appendix H: CTQ 59 Appendix J: MCSDS 64
Effect of immune reconstitution on resistance to Brugia pahangi in congenitally athymic nude mice.

The dichotomy of resistance to Brugia pahangi (Nematoda: Filarioidea) between nonsusceptible, euthymic C3H/HeN mice, heterozygotic for the "nu" gene (+/nu), and susceptible, congenitally-athymic "nude" (nu/nu) C3H/HeN mice, suggests that resistance is thymus-dependent. To test this hypothesis, the effect of syngeneic neonatal thymus grafts and neonatal thymus cell suspensions on recovery of worms at day 40 PI, and responses to Concanavalin A (Con A) were examined in reconstituted nudes. Nude recipients of a thymus graft 7 or 14 wk before subcutaneous inoculation with 50 infective larvae (L3) yielded no worms and responded strongly to Con A. Serum from these mice reacted in two lines of identity with serum from similarly-infected heterozygotes by double radial immunodiffusion against an adult worm saline extract. Nude recipients of a thymus 2 days or 3 wk before inoculation harbored an average of three or two worms, respectively. Intravenous injection of nude recipients with 10(7) or 10(8) neonatal thymus cells seven weeks before inoculation was less effective in conferring resistance to B. pahangi and responsiveness to Con A. Complete resistance to B. pahangi could be adoptively transferred to nude mice by 10(8) spleen cells obtained from infection-primed heterozygotes and injected intravenously on the day of larval inoculation. The same numbers of worms were significantly reduced. less effective when injected 3 wk before inoculation, although numbers of worms were significantly reduced. Passive transfer of primed heterozygote serum, containing high titers of antibodies to adult worm and larval antigens, failed to protect nude recipients against a larval inoculum in the absence of cellular reconstitution. (ABSTRACT TRUNCATED AT 250 WORDS)
A Study of Search Attention and Stock Returns Cross Predictability

This study investigates a novel application of correlated online searches in predicting stock performance across supply chain partners. If two firms are economically dependent through supply-chain relationship and if information related to both firms diffuses in the market slowly (rapidly), then our ability to predict stock returns increases (vanishes). Using supply-chain data and weekly co-search network of supply-chain partners from Bloomberg and Yahoo! Finance, respectively, we find that when investors of a focal stock pay less attention to its supply-chain partners, we can use lagged partner returns to predict the future return of the focal stock. When investors’ co-attention to focal and partner stocks is high, the predictability is low. We contribute to the growing literature on aggregate search and economics of networks by demonstrating the inferential power and economic implications of search networks.