Miracle-dz/UniFAR-FTUs huggingface dataset:
Regeneration of sensory cells after laser ablation in the lateral line system: hair cell lineage and macrophage behavior revealed by time- lapse video microscopy

The regeneration of sensory hair cells in lateral line neuromasts of axolotls was investigated via nearly continuous time-lapse microscopic observation after all preexisting hair cells were killed by a laser microbeam. The laser treatments left neuromasts with one resident cell type, which was supporting cells. Over the course of 1 week, replacement hair cells arose either directly via differentiation of cells present in the epithelium from the beginning of the time-lapse period or via the development of cells produced after one or two divisions of supporting cells. All of the cell divisions that produced hair cells were asymmetrical. During the first hour after the treatment, macrophages and smaller leukocytes were attracted to the laser-treated neuromasts. The smaller leukocytes returned to control levels 48-60 hr after the treatment, whereas macrophages remained active there throughout the period of hair cell replacement. Macrophage incidence peaked 36-48 hr after the laser treatment. Macrophages phagocytosed damaged hair cells and supporting cells, as well as new cells and preexisting cells without recognizable damage. The results provide direct evidence of hair cells arising as progeny produced from the divisions of supporting cells, evidence of hair cells and supporting cells arising from the same cell division, evidence relating to the timing of hair cell differentiation, and indirect evidence pertaining to proposals that hair cells sometimes arise via conversion of cells without an intervening division. The results also suggest that macrophages may influence early stages in the process of hair cell regeneration.
Clinical Assessment of Motor Imagery After Stroke

Objective . The aim of this study was to investigate: (1) the effects of a stroke on motor imagery vividness as measured by the Kinesthetic and Visual Imagery Questionnaire (KVIQ-20); (2) the influence of the lesion side; and (3) the symmetry of motor imagery. Methods. Thirty-two persons who had sustained a stroke, in the right (n = 19) or left (n = 13) cerebral hemisphere, and 32 age-matched healthy persons participated. The KVIQ-20 assesses on a 5-point ordinal scale the clarity of the image (visual scale) and the intensity of the sensations (kinesthetic scale) that the subjects are able to imagine from the first-person perspective. Results. In both groups, the visual scores were higher (P = .0001) than the kinesthetic scores and there was no group difference. Likewise, visual scores remained higher than kinesthetic scores irrespective of the lesion side. The visual scores poststroke were higher (P = .001) when imagining upper limb movements on the unaffected side than those on the affected side. When focusing on the lower limb only, however, the kinesthetic scores were higher (P = .001) when imagining movements of the unaffected compared to those on the affected side. Conclusions. The vividness of motor imagery poststroke remains similar to that of age-matched healthy persons and is not affected by the side of the lesion. However, after stroke motor imagery is not symmetrical and motor imagery vividness is better when imagining movements on the unaffected than on the affected side, indicating an overestimation possibly related to a hemispheric imbalance or a recalibration of motor imagery perception.
Explicit and Implicit Emotional Expression in Bulimia Nervosa in the Acute State and after Recovery

Expression of emotional state is considered to be a core facet of an individual's emotional competence. Emotional processing in BN has not been often studied and has not been considered from a broad perspective. This study aimed at examining the implicit and explicit emotional expression in BN patients, in the acute state and after recovery. Sixty-three female participants were included: 22 BN, 22 recovered BN (R-BN), and 19 healthy controls (HC). The clinical cases were drawn from consecutive admissions and diagnosed according to DSM-IV-TR diagnostic criteria. Self reported (explicit) emotional expression was measured with State-Trait Anger Expression Inventory-2, State-Trait Anxiety Inventory, and Symptom Check List-90 items-Revised. Emotional facial expression (implicit) was recorded by means of an integrated camera (by detecting Facial Feature Tracking), during a 20 minutes therapeutic video game. In the acute illness explicit emotional expression [anxiety (p<0.001) and anger (p<0.05)] was increased. In the recovered group this was decreased to an intermediate level between the acute illness and healthy controls [anxiety (p<0.001) and anger (p<0.05)]. In the implicit measurement of emotional expression patients with acute BN expressed more joy (p<0.001) and less anger (p<0.001) than both healthy controls and those in the recovered group. These findings suggest that there are differences in the implicit and explicit emotional processing in BN, which is significantly reduced after recovery, suggesting an improvement in emotional regulation.
The Impact of IT-Based Trading on Securities Markets

The emergence of IT-based trading activities like algorithmic trading or high-frequency trading alters the traditional trading environment within financial markets. Thus, the question arises whether this technological arms race positively affects market quality or represents a risk related to market integrity. Within this study, we evaluate the order-to-trade-ratio for measuring overall IT-based trading activity. Furthermore, in a longitudinal study, we assess the impact of the order-to-trade-ratio on market quality. We find strong indications that price uncertainty has decreased with an increased order-to-trade-ratio and therefore has a positive impact on financial markets. However, the mere upgrade of the trading systems does not relate into increased market liquidity.
E-Learning: Investigating University Students Acceptance of Technology

Information Communication Technology (ICT) is reshaping form and mode of delivery of higher education world wide. Some of the main challenges in education are access issues, and costs. In order to overcome those challenges ICT can play an important role. The application of ICT in the education sector can be referred to as e-learning, and comprises the use of various web-based technological tools with the purpose of disseminating education. The purpose of this study is to investigate what determines university students' acceptance of e-learning by applying the technology acceptance model (TAM). The study was conducted at a Swedish University among business students. The results demonstrate that Perceived usefulness is the main determinant of a student's acceptance of e-learning
The Star-forming Region NGC 346 in the Small Magellanic Cloud with Hubble Space Telescope ACS Observations. II. Photometric Study of the Intermediate-Age Star Cluster BS 90

We present the results of our investigation of the intermediate-age star cluster BS 90, located in the vicinity of the H II region N66 in the SMC, observed with HST ACS. The high-resolution data provide a unique opportunity for a very detailed photometric study performed on one of the rare intermediate-age rich SMC clusters. The complete set of observations is centered on the association NGC 346 and contains almost 100,000 stars down to V ≃ 28 mag. In this study we focus on the northern part of the region, which covers almost the whole stellar content of BS 90. We construct its stellar surface density profile and derive structural parameters. Isochrone fits on the CMD of the cluster results in an age of about 4.5 Gyr. The luminosity function is constructed and the present-day mass function of BS 90 has been obtained using the mass-luminosity relation, derived from the isochrone models. We found a slope between -1.30 and -0.95, comparable to or somewhat shallower than a typical Salpeter IMF. Examination of the radial dependence of the mass function shows a steeper slope at larger radial distances, indicating mass segregation in the cluster. The derived half-mass relaxation time of 0.95 Gyr suggests that the cluster is mass segregated due to its dynamical evolution. From the isochrone model fits we derive a metallicity for BS 90 of [Fe/H] = -0.72, which adds an important point to the age-metallicity relation of the SMC. We discuss our findings on this relation in comparison to other SMC clusters.
TQM and Organization Performance : The Mediation and Moderation Fit

Total Quality Management (TQM) is a unified organizational setting to improve the quality at every function and level of organization . The objective of this study is to measure the effect of TQM practices on the performance of the telecom sector of Pakistan . Telecom sector is continuously striving to improve the quality of its service s to achieve business objectives . A conceptual framework model to investigate the said relationship is developed and tested . The results are based on a survey instrument developed through an extensive literature review . To analyze the complex relationship between the variables , Structural Equation Modeling (SEM) methodology was employed . The data collected from 212 respondents was used to test the model by using AMOS 16. Analysis of the data supports a strong and positive association between the TQM practices and quality performance, innovation performance and organization performance (OP) respectively . This study found that innovation performance has partial mediating impact between TQM and OP , whereas, QP mediation impact was not established . Moreover, culture of support has a moder ating role in the relationship between TQM practices an d the OP . ( Tahir Iqbal, Bilal Ahmad Khan, Nadeem Talib, Nawar Khan . TQM and Organization Performance: The Mediation and Moderation Fit . Life Sci J 2012;9( 4 ): 1571 - 1582 ) (ISSN:1097 - 8135). http://www.lifesciencesite. com . 239
Is carotid sonography a useful tool for predicting functional capabilities in ischemic stroke patients following carotid artery stenting?

Abstract Carotid stenosis is a major cause of stroke and timely intervention with stenting manipulation can significantly reduce the risk of secondary stroke. The impact of stenting procedures on patient functional capabilities has not yet been explored. The primary aim of this study was to examine associations between periprocedural carotid sonography parameters and post-treatment functional capabilities in stroke patients. Sixty-seven patients who received carotid stenting at 1 angiography laboratory were included. Prestenting and poststenting carotid duplex data were recorded and resistance index (RI) differences at various carotid system locations were compared. The modified Rankin Scale (mRS) was used to assess functional capability. All of the studied parameters were analyzed by SPSS (version 16.0, SPSS Inc, Chicago, IL). Following stenting, mRS scores improved (n = 44) or remained stationary (n = 23). Net contralateral internal carotid artery (ICA) RI for patients with improved mRS was lower compared to that for patients with stationary mRS (median = 0.040 vs 0.11; P = 0.003). The contralateral common carotid artery RI before and after stenting differed significantly (P < 0.050) in both. The ipsilateral ICA RI differed (P < 0.050) only in patients with improved mRS. The difference in mean transit time, Barthel index, net ipsilateral ICA RI, net contralateral external carotid artery RI, postipsilateral common carotid artery RI, and postipsilateral ICA RI differed significantly between different baseline stroke severity groups (P < 0.050). Carotid artery stenting improved physical function in a proportion of ischemic stroke patients with carotid stenosis. Carotid ultrasound is a useful assessment tool to predict likely functional outcomes following carotid artery stenting.
Survival of the Fittest or the Fattest ?

This paper studies the impact that capital market imperfections have on the natural selection of the most eecient rms by estimating the eeect of the pre-deregulation level of leverage on the survival of trucking rms after the Carter deregulation. Highly leveraged carriers are less likely to survive the deregulation shock, even after controlling for various measures of eeciency. This eeect is stronger in the imperfectly competitive segment of the motor carrier industry. High debt seems to aaect survival by curtailing investments and reducing the price per-ton-mile that a carrier can aaord to charge after deregulation. I wish to thank Abhay Pande for interesting me in the trucking industry,
Discovery of X-ray emission from the eclipsing brown-dwarf binary 2MASS J05352184-0546085

The eclipsing brown-dwarf binary system 2MASS J05352184-0546085 is a case sui generis. For the first time, it allows a detailed analysis of the individual properties of young brown dwarfs, in particular, masses, and radii, and the temperature ratio of the system components can be determined accurately. The system shows a “temperature reversal" with the more massive component being the cooler one, and both components are found to be active. We analyze X-ray images obtained by Chandra and XMM-Newton containing 2MASS J05352184-0546085 in their respective field of view. The Chandra observatory data show a clear X-ray source at the position of 2MASS J05352184-0546085, whereas the XMM-Newton data suffer from contamination from other nearby sources, but are consistent with the Chandra detection. No indications of flaring activity are found in either of the observations (together ≈70 ks), and we thus attribute the observed flux to quiescent emission. With an X-ray luminosity of 3 × 10 28 erg/ sw e fi nd anLX/Lbol-ratio close to the saturation limit of 10 −3 and an LX/LHα-ratio consistent with values obtained from low-mass stars. The X-ray detection of 2MASS J05352184-0546085 reported here provides additional support for the interpretation of the temperature reversal in terms of magnetically suppressed convection, and suggests that the activity phenomena of young brown dwarfs resemble those of their more massive counterparts.
Critical thinking and employability of computer-related graduates: The Malaysian context

This quantitative study examines the relationship between critical thinking and employability in the Malaysian higher education context. This research seeks future ICT graduates’ perceptions of their perceived ability and importance to employment of critical thinking strategies in relation to employer needs. The setting of this research was 10 public universities located in Malaysia and the Multimedia Super Corridor (MSC) where the employers of ICT companies were located. The research methodology consisted of surveys aimed at both future graduates and employers of ICT related companies following a mixed model approach. Three surveys were developed for this study, firstly, to capture the concerns of soon-to-be graduates in the IT sector and secondly, employers in relation to the employability of graduates. Thirdly, the research examines the critical thinking capabilities of students in relation to their future employment. Results indicate that student respondents rated their own critical thinking ability lower than what they perceived is needed in future work. Employers also express reservations about graduates’ readiness for employment. Findings suggest that the most basic employability skill apart from literacy and numeracy were communication skills, closely associated with soft skills. Additionally, findings stress the role of English language competency and a proactive, problem-solving approach as being welcome by employers. Both future graduates and employers stress the importance of non-job specific skills and this is supported overall by findings. This research suggests that faculties of higher level institutions should aim to design courses which include the skills that graduates need and employers expect. Employers need to communicate and collaborate with academia in relation to the competency levels of graduates to ensure undergraduates are provided with employability skills suited to Malaysia’s role in the 21st century global economy.
Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Apoptotic cells are considered to be a major source for autoantigens in autoimmune diseases such as systemic lupus erythematosus (SLE). In agreement with this, defective clearance of apoptotic cells has been shown to increase disease susceptibility. Still, little is known about how apoptotic cell–derived self-antigens activate autoreactive B cells and where this takes place. In this study, we find that apoptotic cells are taken up by specific scavenger receptors expressed on macrophages in the splenic marginal zone and that mice deficient in these receptors have a lower threshold for autoantibody responses. Furthermore, antibodies against scavenger receptors are found before the onset of clinical symptoms in SLE-prone mice, and they are also found in diagnosed SLE patients. Our findings describe a novel mechanism where autoantibodies toward scavenger receptors can alter the response to apoptotic cells, affect tolerance, and thus promote disease progression. Because the autoantibodies can be detected before onset of disease in mice, they could have predictive value as early indicators of SLE.
A New Quantum Data Processing Inequality

Quantum data processing inequality bounds the set of bipartite states that can be generated by two far apart parties under local operations; having access to a bipartite state as a resource, two parties cannot locally transform it to another bipartite state with a mutual information greater than that of the resource state. But due to the additivity of quantum mutual information under tensor product, the data processing inequality gives no bound when the parties are provided with arbitrary number of copies of the resource state. In this paper, we introduce a measure of correlation on bipartite quantum states, called maximal correlation, that is not additive and gives the same number when computed for multiple copies. Then by proving a data processing inequality for this measure, we find a bound on the set of states that can be generated under local operations even when an arbitrary number of copies of the resource state is available.
Lying Pose Recognition for Elderly Fall Detection

This paper proposes a pipeline for lying pose recognition from single images, which is designed for health-care robots to find fallen people. We firstly detect object bounding boxes by a mixture of viewpoint-specific part based model detectors and later estimate a detailed configuration of body parts on the detected regions by a finer tree-structured model. Moreover, we exploit the information provided by detection to infer a reasonable limb prior for the pose estimation stage. Additional robustness is achieved by integrating a viewpointspecific foreground segmentation into the detection and body pose estimation stages. This step yields a refinement of detection scores and a better color model to initialize pose estimation. We apply our proposed approach to challenging data sets of fallen people in different scenarios. Our quantitative and qualitative results demonstrate that the part-based model significantly outperforms a holistic model based on same feature type for lying pose detection. Moreover, our system offers a reasonable estimation for the body configuration of varying lying poses.
Technical Differences and Inter-industry Trade in the Nordic Countries

Interindustry specialization in intra-Nordic trade is studied in the context of a simple model where technical differences and capital-labor ratios interact in determining net export. The empirical test largely concurs with the theory. Countries are net exporters in industries where their relative labor productivity is high and where they have high R&D expenditures. In addition, countries are net exporters in industries that make intensive use of their abundant factor. Copyright 1996 by The editors of the Scandinavian Journal of Economics.
Quality of life in elderly patients following coronary artery bypass grafting

Background Surgical revascularization of the coronary arteries leads to changes in quality of life (QoL) for patients with coronary heart disease. The aim of this work was to monitor QoL, considering cognitive function, depression, and activities of daily living in elderly patients after coronary artery bypass grafting (CABG). Methods This study included 65 patients (29 women and 36 men) aged 61–74 years with stable coronary heart disease who underwent CABG. The control group included 29 women and 36 men aged 61–74 years who were not suffering from coronary heart disease. The questionnaires used in the study canvassed QoL (Nottingham Health Profile), cognitive function, depression, and basic and instrumental activities of daily living. The research was conducted before surgery and repeated 6 and 12 months after surgery. Results QoL was comparable between women and men and was lower than in the control group (P<0.05). After CABG, the values for particular domains of QoL improved more in men than in women. There was a reduction in the severity of depression 6 months after surgery in men and 12 months after surgery in women. Conclusion Elderly patients with coronary heart disease have decreased QoL, which normalizes in men and improves in women after CABG.
Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S 97

Many cell types exhibit an asymmetric subdivison of the plasma membrane and the underlying cytocortex into discrete domains with specialized structural and functional properties. This is mediated by the differential localization of distinct, membrane-anchored protein complexes including those forming cellular junctions. The importance of such partitioning is particularly evident in epithelial cells, in which apico-basal polarity largely depends on the well-ordered juxtaposition of molecularly distinct junctions, e.g. adherens junctions, tight junctions or septate junctions (Tepass et al., 2001; Knust, 2002; Knust and Bossinger, 2002). Similarly, diverse multi-protein complexes are established side-by-side along the pre-and postsynaptic membranes of neurons or their non-neuronal targets (Baude et al. The precise spatial arrangement of such complexes relies on the efficient sorting and selective retention of their components. Studies addressing these requirements have revealed that complex-specific combinations of submembraneous proteins provide a scaffold of adapter modules, primarily PDZ-type domains, to which transmembrane proteins and cytoplasmic components