Miracle-dz/UniFAR-FTUs huggingface dataset:
Spine Curvature Analysis between Participants with Obesity and Normal Weight Participants: A Biplanar Electromagnetic Device Measurement

To analyse and compare standing thoracolumbar curves in normal weight participants and participants with obesity, using an electromagnetic device, and to analyse the measurement reliability. Material and Methods. Cross-sectional study was carried out. 36 individuals were divided into two groups (normal-weight and participants with obesity) according to their waist circumference. The reference points (T1–T8–L1–L5 and both posterior superior iliac spines) were used to perform a description of thoracolumbar curvature in the sagittal and coronal planes. A transformation from the global coordinate system was performed and thoracolumbar curves were adjusted by fifth-order polynomial equations. The tangents of the first and fifth lumbar vertebrae and the first thoracic vertebra were determined from their derivatives. The reliability of the measurement was assessed according to the internal consistency of the measure and the thoracolumbar curvature angles were compared between groups. Results. Cronbach's alpha values ranged between 0.824 (95% CI: 0.776–0.847) and 0.918 (95% CI: 0.903–0.949). In the coronal plane, no significant differences were found between groups; however, in sagittal plane, significant differences were observed for thoracic kyphosis. Conclusion. There were significant differences in thoracic kyphosis in the sagittal plane between two groups of young adults grouped according to their waist circumference.
The Perceptual Grouping Criterion of Colinearity is Reflected by Anisotropies of Connections in the Primary Visual Cortex

An important step in the processing of visual patterns is the segmentation of the retinal image. Neuronal responses evoked by the contours of individual objects need to be identified and associated for further joint processing. These grouping operations are based on a number of Gestalt criteria. Here we report that connections in the visual cortex of the cat exhibit a highly significant anisotropy, preferentially linking neurons activated by contours that have similar orientation and are aligned colinearly. These anatomical data suggest a close relation between the perceptual grouping criterion of colinearity and the topology of tangential intracortical connections. We propose that tangential intracortical connections support perceptual grouping by modulating the saliency of distributed cortical responses in a context‐dependent way. The present data are compatible with the hypothesis that the criteria for this grouping operation are determined by the architecture of the tangential connections.
Adult Learners, Adult Education, And The Community

An overview of concepts and research independent adult learning - a conceptual analysis the adult learning iceberg community adult education adult learning groups, community development and community action identifying and researching adult learners in the community supporting adult learners in the community - the individual mode supporting adult learners in the community - the group mode. Conclusion - a personal postscript.
Comparison of Dimensional Accuracy between Open-Tray and Closed-Tray Implant Impression Technique in 15° Angled Implants

Statement of Problem: Various impression techniques have different effects on the accuracy of final cast dimensions. Meanwhile; there are some controversies about the best technique. Purpose: This study was performed to compare two kinds of implant impression methods (open tray and closed tray) on 15 degree angled implants. Materials and Method: In this experimental study, a steel model with 8 cm in diameter and 3 cm in height were produced with 3 holes devised inside to stabilize 3 implants. The central implant was straight and the other two implants were 15° angled. The two angled implants had 5 cm distance from each other and 3.5 cm from the central implant. Dental stone, high strength (type IV) was used for the main casts. Impression trays were filled with poly ether, and then the two impression techniques (open tray and closed tray) were compared. To evaluate positions of the implants, each cast was analyzed by CMM device in 3 dimensions (x,y,z). Differences in the measurements obtained from final casts and laboratory model were analyzed using t-Test. Results: The obtained results indicated that closed tray impression technique was significantly different in dimensional accuracy when compared with open tray method. Dimensional changes were 129 ± 37μ and 143.5 ± 43. 67μ in closed tray and open tray, while coefficient of variation in closed- tray and open tray were reported to be 27.2% and 30.4%, respectively. Conclusion: Closed impression technique had less dimensional changes in comparison with open tray method, so this study suggests that closed tray impression technique is more accurate.
Subharmonic resonant excitation of edge waves by breaking surface waves

Abstract. Parametric excitation of edge waves with a frequency 2 times less than the frequency of surface waves propagating perpendicular to the inclined bottom is investigated in laboratory experiments. The domain of instability on the plane of surface wave parameters (amplitude–frequency) is found. The subcritical instability is observed in the system of parametrically excited edge waves. It is shown that breaking of surface waves initiates turbulent effects and can suppress the parametric generation of edge waves.
Training and Evaluating a German Named Entity Recognizer with Semantic Generalization

We present a freely available optimized Named Entity Recognizer (NER) for German. It alleviates the small size of available NER training corpora for German with distributional generalization features trained on large unlabelled corpora. We vary the size and source of the generalization corpus and find improvements of 6% F1 score (in-domain) and 9% (out-of-domain) over simple supervised training.
In Vitro Demonstration of Focused Ultrasound Thrombolysis Using Bifrequency Excitation

Focused ultrasound involving inertial cavitation has been shown to be an efficient method to induce thrombolysis without any pharmacological agent. However, further investigation of the mechanisms involved and further optimization of the process are still required. The present work aims at studying the relevance of a bifrequency excitation compared to a classical monofrequency excitation to achieve thrombolysis without any pharmacological agent. In vitro human blood clots were placed at the focus of a piezoelectric transducer. Efficiency of the thrombolysis was assessed by weighing each clot before and after sonication. The efficiencies of mono- (550 kHz) and bifrequency (535 and 565 kHz) excitations were compared for peak power ranging from 70 W to 220 W. The thrombolysis efficiency appears to be correlated to the inertial cavitation activity quantified by passive acoustic listening. In the conditions of the experiment, the power needed to achieve 80% of thrombolysis with a monofrequency excitation is reduced by the half with a bifrequency excitation. The thermal effects of bifrequency and monofrequency excitations, studied using MR thermometry measurements in turkey muscle samples where no cavitation occurred, did not show any difference between both types of excitations when using the same power level.
Near-optimal routing for contour detection in wireless sensor networks

Wireless sensor networks are often deployed to monitor scalar fields. Commonly, these networks employ a query-based architecture, where specific data are requested by the sink node, and the network responds. Contours or isolines are compact representations of the state of a scalar field, and are useful abstractions of scalar field behavior. Previously researchers have examined algorithms and policies for detecting contours in query-based sensor networks, but have only addressed individual components of the process. In this paper we present a set of algorithms for contour detection in WSNs, and associated oracle functions to provide an unbiased optimality comparison. We show that our algorithms, and in particular our response and aggregation policy provide near-optimal performance in simulated networks measuring physically realistic scalar fields.
Recovery from early blindness : a case study

Photograph: Tobias cures his father's blindness-Bernardo Strozzi 1581–1644 [The Metropolitan Museum of Art, Purchase 1957 Mary Wetmore Shively Bequest, in memory of her husband, Henry L. Shively] Recovery from Early Blindness-A Case Study 2 Foreword Although it is nearly 300 years since Molyneux posed his celebrated query, interest in the problem of recovery of vision after early and long-standing blindness is of comparatively recent origin. In 1932, Dr. M. von Senden carefully reviewed the literature on the perception of space and shape in the congenitally blind before and after operation and arrived at some important conclusions. In particular, he stressed the slow, laborious and imperfect way in which the perception of form is acquired by these patients and their liability to emotional " crises " as they come to discover the true extent of their disability as sighted persons. Unfortunately, Dr. von Senden's monograph remained little known to psychologists, at all events in this country, and it was not until 1949, when Dr. Donald Hebb published his fascinating book on The Organisation of Behavior, that its significance came to be at all widely appreciated. As every psychologist knows, Dr. Hebb placed considerable weight on Herr von Senden's evidence and believed it to throw important light on the nature of visual perception and its development in infancy. Although there is disagreement regarding the interpretation of this evidence, there can be no doubt as to the fresh and stimulating influence which Dr. Hebb's ideas have had upon contemporary psychological thought. One of the main obstacles to informed discussion of Dr. Hebb's theories has been the inaccessibility of the clinical evidence. This, it is true, has been remedied to some extent by the publication, in 1960, of an English translation of Dr. von Senden's monograph but even so the position is far from satisfactory. It was never the author's intention to assemble detailed case reports and it is not always easy to distinguish between the facts as recorded by others and the interpretation which Dr. von Senden has placed upon them. If for only this reason, the addition of a fresh and well-studied case to the widely dispersed literature will be warmly welcomed. The authors of this monograph have provided a full description of the history and progress of a man, effectively blind almost from birth, who underwent two operations for corneal grafting at the age of 52, as a result of which …
Trees, windows and tiles for wavelet image compression

We investigate the task of compressing an image by using different probability models for compressing different regions of the image. In an earlier paper, we introduced a class of probability models for images, the k-rectangular tiling of an image, which is formed by partitioning the image into k rectangular regions and generating the coefficients within each region by using a probability model selected from a finite class C of probability models. We also describe a computationally efficient sequential probability assignment algorithm that is able to code an image with a code length that is close to the code length produced by the best model in the class. In this paper, we investigate the performance of the algorithm experimentally on the task of compressing wavelet subbands. We compare the method with compression methods that aim to compress as well as the best pruning of a quadtree and compression methods that exploit the local statistics in a window around the coefficient being compressed. For a class C consisting of a small number of Laplacian distributions and the uniform distribution, we find that the best tiling method works best, but the difference in performance is significant for only a few of the images tested.
Using-greedy reinforcement learning methods to further understand ventromedial prefrontal patients ’ deficits on the Iowa Gambling Task

An important component of decision making is evaluating the expected result of a choice, using past experience. The way past experience is used to predict future rewards and punishments can have profound effects on decision making. The aim of this study is to further understand the possible role played by the ventromedial prefrontal cortex in decision making, using results from the Iowa Gambling Task (IGT). A number of theories in the literature offer potential explanations for the underlying cause of the deficit(s) found in bilateral ventromedial prefrontal lesion (VMF) patients on the IGT. An error-driven -greedy reinforcement learning method was found to produce a good match to both human normative and VMF patient groups from a number of studies. The model supports the theory that the VMF patients are less strategic (more explorative), which could be due to a working memory deficit, and are more reactive than healthy controls. This last aspect seems consistent with a ‘myopia’ for future consequences. c © 2007 Elsevier Ltd. All rights reserved.
Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study[S]

Chronic alcohol consumption is associated with fatty liver disease in mammals. The object of this study was to gain an understanding of dysregulated lipid metabolism in alcohol-fed C57BL/6 mice using a targeted lipidomic approach. Liquid chromatography tandem mass spectrometry was used to analyze several lipid classes, including free fatty acids, fatty acyl-CoAs, fatty acid ethyl esters, sphingolipids, ceramides, and endocannabinoids, in plasma and liver samples from control and alcohol-fed mice. The interpretation of lipidomic data was augmented by gene expression analyses for important metabolic enzymes in the lipid pathways studied. Alcohol feeding was associated with i) increased hepatic free fatty acid levels and decreased fatty acyl-CoA levels associated with decreased mitochondrial fatty acid oxidation and decreased fatty acyl-CoA synthesis, respectively; ii) increased hepatic ceramide levels associated with higher levels of the precursor molecules sphingosine and sphinganine; and iii) increased hepatic levels of the endocannabinoid anandamide associated with decreased expression of its catabolic enzyme fatty acid amide hydrolase. The unique combination of lipidomic and gene expression analyses allows for a better mechanistic understanding of dysregulated lipid metabolism in the development of alcoholic fatty liver disease.
The role of stereotactic radiotherapy in patients with growth hormone-secreting pituitary adenoma.

CONTEXT Single-session stereotactic radiotherapy (SR) may be a potential adjuvant treatment in acromegaly. OBJECTIVE We analyzed the safety and efficacy of SR in patients who had previously received maximal surgical debulking at our center. DESIGN The study was a retrospective analysis of hormonal, radiological, and ophthalmologic data collected in a predefined protocol from 1994 through 2006. SETTING The study was performed at a university hospital. PATIENTS Eighty-three acromegalic patients, 52 women and 31 men, with a mean age of 42.6 +/- 1.2 yr, participated in the study. The median follow-up was 69 months (interquartile range 44-107 months). INTERVENTION The patients were treated with SR for residual or recurrent GH-secreting adenoma. MAIN OUTCOME MEASURE Normalization of age- and sex-adjusted IGF-I levels together with a basal GH level below 2.5 microg/liter without concomitant GH-suppressive drugs was the goal of therapy. RESULTS Fifty patients (60.2%) reached the main outcome of the study. The rate of remission was 52.6% at 5 yr [95% confidence interval (CI) 40.6-64.6%]. Another 13 patients (15.7%), who were resistant to somatostatin analogs, were in remission after SR. Multivariate analysis showed that low basal GH and IGF-I levels were associated with a favorable outcome. No serious side effects occurred after SR. The 5-yr cumulative risk of new onset hypogonadism, hypothyroidism, or hypoadrenalism was 3.6% (95% CI 0-8.6%), 3.3% (95% CI 0-7.7%), and 4.9% (95% CI 0-10.4%), respectively. CONCLUSION In a highly selected group of acromegalic patients, SR treatment had good efficacy and safety. This may lead to reconsider the role of SR in the therapeutic algorithm of acromegaly.
A Bridgeless Boost Rectifier for Low-Voltage Energy Harvesting Applications

In this paper, a single-stage ac–dc power electronic converter is proposed to efficiently manage the energy harvested from electromagnetic microscale and mesoscale generators with low-voltage outputs. The proposed topology combines a boost converter and a buck-boost converter to condition the positive and negative half portions of the input ac voltage, respectively. Only one inductor and capacitor are used in both circuitries to reduce the size of the converter. A 2 cm × 2 cm, 3.34-g prototype has been designed and tested at 50-kHz switching frequency, which demonstrate 71% efficiency at 54.5 mW. The input ac voltage with 0.4-V amplitude is rectified and stepped up to 3.3-V dc. Detailed design guidelines are provided with the purpose of minimizing the size, weight, and power losses. The theoretical analyses are validated by the experiment results.
Low-molecular-weight AGEs are associated with GFR and anemia in patients with type 2 diabetes.

BACKGROUND Advanced glycation end products (AGEs) are implicated in the development and progression of diabetic nephropathy. We examined the predictors of low-molecular-weight (LMW) AGEs in a cross-sectional survey of 604 patients with type 2 diabetes in a single clinic. METHODS A clinical history and results of routine blood and urine testing were obtained for all patients over a 2-year period. Fluorescent LMW AGEs were estimated in serum samples taken concurrently, using an established flow injection method. Predictors of LMW AGEs were identified using multiple regression analysis. RESULTS LMW AGEs were 34% higher in patients with diabetes than nondiabetic volunteers from the same community (P < 0.001). Independent predictors for LMW AGEs in patients with diabetes were glomerular filtration rate (GFR) and hemoglobin (both P < 0.001). While patients with renal impairment and anemia had the highest levels of LMW AGEs, both GFR and hemoglobin remained predictive when patients with a serum creatinine or hemoglobin within the "normal range" were analyzed separately. Patients with hyperfiltration had significantly lower LMW AGEs than those with normal renal function. Gender was also a significant independent predictor of LMW AGEs in patients without anemia. However, LMW AGEs were not associated with metabolic control or the presence of macrovascular disease. CONCLUSION Circulating levels of LMW AGEs are elevated in patients with diabetes, especially those with impaired renal function or anemia. These findings extend the evidence for an association between AGEs and progressive renal injury in patients with type 2 diabetes. Whether LMW AGEs contribute to, or are a marker of, renal damage needs to be established by prospective studies.
Yes: The Symptoms of OCD and Depression Are Discrete and Not Exclusively Negative Affectivity

Although Obsessive-Compulsive Disorder (OCD) and Depression are classified as separate disorders, the high incidence of co-morbidity and the strong correlations between measures of each has led to debate about the nature of their relationship. Some authors have proposed that OCD is in fact a mood disorder while others have suggested that the two disorders are grounded in negative affectivity. A third proposition is that depression is an essential part of OCD but that OCD is a separate disorder from depression. The aim in this study was to investigate these diverse propositions in a non-clinical sample and also to determine whether factors implicated in each, that is anxious and depressive cognitions, hopelessness, and self-criticism, would demonstrate commonality as predictors of the symptoms of OCD and of depression. Two hundred participants (59% female) (M age = 34 years, SD = 16) completed the Padua Inventory, Carroll Rating Scale, Cognitions Checklist, Self-Criticism Scale, Beck Hopelessness Scale, Buss-Durkee Hostility Inventory-Revised and a Negative Affectivity Schedule. Results indicated a strong correlation between OCD and depression, depression, and negative affectivity but a weaker relationship between OCD and negative affectivity. Path analyses revealed that both anxious and depressive cognitions, as well as hostility predicted both disorders but the Beta-weights were stronger on OCD. Self-criticism predicted only depression while hopelessness failed to predict either disorder but was itself predicted by depressive cognitions. Depression was a stronger indicator of negative affect than OCD and while OCD positively predicted depression, depression was a negative indicator of OCD. These results support the hypothesis that OCD and depression are discrete disorders and indicate that while depression is implicated in OCD, the reverse does not hold. While both disorders are related to negative affectivity, this relationship is much stronger for depression thus failing to confirm that both are subsumed by a common factor, in this case, negative affectivity. The proposition that depression is part of OCD but that OCD is not necessarily implicated in depression and is, in fact, a separate disorder, is supported by the current model. Further research is required to support the utility of the model in clinical samples.
Stability and variability of motivation to change in anorexia nervosa

Resistance to treatment is common among anorexic clients. Three studies indicated that although readiness to change and self-efficacy are applicable to this population, there is a large degree of variability and stability between symptoms. Multi-dimensional, continuous measures of readiness to change and self-efficacy may provide a more accurate, informative assessment.
Immunoglobulin Expressions Are Only Associated With MCPyV-positive Merkel Cell Carcinomas But Not With MCPyV-negative Ones: Comparison of Prognosis

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer, often associated with Merkel cell polyomavirus (MCPyV). Recently, immunoglobulin (Ig) expression was reported in MCC, thereby suggesting that B cells might be their cellular ancestors. We tested 30 MCCs (20 MCPyV-positive and 10 MCPyV-negative) using immunohistochemistry for the expressions of IgG, IgA, IgM, Ig&kgr;, Ig&lgr;, terminal desoxynucleotidyl transferase, paired box gene 5 (PAX5), octamer transcription factor-2 (Oct-2), and sex-determining region Y-box 11 (SOX11). We performed in situ hybridization for Ig&kgr;-mRNA or Ig&lgr;-mRNA and Ig heavy chain (IgH) gene rearrangement (IgH-R) analyses. The expressions of PAX5, TdT, Oct-2, and SOX11 were not significantly different between MCPyV-positive and MCPyV-negative MCCs. At least 1 of IgG, IgA, IgM, or Ig&kgr; was expressed in MCPyV-positive (14/20, 70%) and none in MCPyV-negative MCCs (P=0.0003). There was a higher tendency for Ig&kgr;-mRNA expression (7/19, using in situ hybridization) and IgH-R (10/20, using polymerase chain reaction) in MCPyV-positive than in MCPyV-negative MCCs (0/10 and 2/10, respectively), thus suggesting a different Ig production pattern and pathogenesis between the 2 types of MCC. Ig expression or IgH-R in MCPyV-positive MCCs might be associated with MCPyV gene integration or expression in cancer cells but do not necessarily suggest a B-cell origin for MCCs. IgH expression or IgH-R nonsignificantly correlated with improved prognosis. However, these might be important factors that influence the survival of neoplastic cells and might allow the development of novel therapies for patients with MCPyV-positive MCCs.