Miracle-dz/UniFAR-FTUs huggingface dataset:
Dissemination of methicillin-resistant Staphylococcus aureus SCCmec type IV and SCCmec type V epidemic clones in a tertiary hospital: challenge to infection control

SUMMARY Two-hundred MRSA strains from inpatients with healthcare-associated (HA) and 100 MRSA strains from outpatients with community-associated (CA) skin and soft tissue infections (SSTIs) were tested for antimicrobial susceptibility, staphylococcal cassette chromosome mec (SCCmec) typing, Panton–Valentine leucocidin (PVL) toxin, seh and arcA genes. Based on SCCmec typing, HA-MRSA isolates were further divided into HA-SCCmec I/II/III MRSA and HA-SCCmec IV/V MRSA, and CA-MRSA isolates into CA-SCCmec I/II/III MRSA and CA-SCCmec IV/V MRSA. SCCmec types were further characterized by pulsed-field gel electrophoresis, spa typing and multi-locus sequence typing. Seventy-five (37·5%) HA-MRSA isolates and 83/100 CA-MRSA isolates were SCCmec IV/V genotype. HA-SCCmec IV/V MRSA was associated with malignancy (P = 0·03) and bone fractures (P = 0·02) compared to CA-SCCmec IV/V MRSA. HA-SCCmec IV/V MRSA was associated with PVL gene carriage compared to HA-SCCmec I/II/III MRSA (P < 0·001). ST22-MRSA-IV (EMRSA-15), ST772-MRSA-V, and ST36-MRSA-IV and ST239:EMRSA-I:III were the major clones identified. Our study documents the emergence of SCCmec IV and SCCmec V MRSA clones in an Indian hospital.
Shared Constitutional Risks for Maternal Vascular-Related Pregnancy Complications and Future Cardiovascular Disease

Maternal predisposition to vascular and metabolic disease may underlie both vascular-related pregnancy complications, such as preeclampsia and intrauterine growth restriction, as well as future maternal cardiovascular disease. We aimed to substantiate this hypothesis with biochemical and anthropometric evidence by conducting an intergenerational case-control study in a Dutch isolated population including 106 women after preeclampsia or intrauterine growth restriction (median follow-up: 7.1 years) and their fathers (n=43) and mothers (n=64), as well as 106 control subjects after uncomplicated pregnancies with their fathers (n=51) and mothers (n=68). Cardiovascular risk profiles were assessed, including fasting glucose, lipids, anthropometrics, blood pressure, intima-media thickness, and metabolic syndrome. We found significantly higher fasting glucose levels, larger waist circumferences, and a 5-fold increased prevalence of hypertension in women with a history of preeclampsia as compared with control subjects (P<0.001). Likewise, their parents had higher glucose levels than control parents (P<0.05). Their mothers had larger waist circumferences and higher blood pressures (P<0.05). Also, women after pregnancies complicated by intrauterine growth restriction had higher glucose levels and increased prevalence of hypertension (P<0.01). Their fathers showed higher glucose levels as well (P<0.05). Mean carotid intima-media thickness was increased in a subset of women after preeclampsia diagnosed with chronic hypertension as compared with those without hypertension (P<0.01). Metabolic syndrome was more prevalent both in women with a history of preeclampsia and their mothers (P<0.05). We demonstrated intergenerational similarities in cardiovascular risk profiles between women after preeclampsia or intrauterine growth restriction and their parents. These findings suggest shared constitutional risks for vascular-related pregnancy complications and future cardiovascular disease.
3 D ShapeNets : A Deep Representation for Volumetric Shape Modeling

3D shape is a crucial but heavily underutilized cue in today’s computer vision system, mostly due to the lack of a good generic shape representation. With the recent availability of inexpensive 2.5D depth sensors (e.g. Microsoft Kinect), it is becoming increasingly important to have a powerful 3D shape model in the loop. Apart from object recognition on 2.5D depth maps, recovering these incomplete 3D shapes to full 3D is critical for analyzing shape variations. To this end, we propose to represent a geometric 3D shape as a probability distribution of binary variables on a 3D voxel grid, using a Convolutional Deep Belief Network. Our model, 3D ShapeNets, learns the distribution of complex 3D shapes across different object categories and arbitrary poses. It naturally supports joint object recognition and shape reconstruction from 2.5D depth maps, and further, as an additional application it allows active object recognition through view planning. We construct a largescale 3D CAD model dataset to train our model, and conduct extensive experiments to study our new representation.
Anthropogenic aerosols and the distribution of past large‐scale precipitation change

The climate response of precipitation to the effects of anthropogenic aerosols is a critical while not yet fully understood aspect in climate science. Results of selected models that participated the Coupled Model Intercomparison Project Phase 5 and the data from the Twentieth Century Reanalysis Project suggest that, throughout the tropics and also in the extratropical Northern Hemisphere, aerosols have largely dominated the distribution of precipitation changes in reference to the preindustrial era in the second half of the last century. Aerosol‐induced cooling has offset some of the warming caused by the greenhouse gases from the tropics to the Arctic and thus formed the gradients of surface temperature anomaly that enable the revealed precipitation change patterns to occur. Improved representation of aerosol‐cloud interaction has been demonstrated as the key factor for models to reproduce consistent distributions of past precipitation change with the reanalysis data.
Predictors of Self-rated Health Status Among Texas Residents

Introduction The purpose of this study was to investigate the predictors of self-rated health status for Texas adults using the current 2003 Behavioral Risk Factor Surveillance System data. Self-rated health is generally accepted as a valid measure of health status in population studies, and understanding its correlates may help public health professionals prioritize health-promotion and disease-prevention interventions. Methods The two research questions addressed by this study involved the predictors of self-rated health: 1) "Do demographic characteristics, health care coverage, leisure-time physical activity, and body mass index predict self-rated health status for Texas residents aged 18 to 64 years? " and 2) "Does choice of interview language (English vs Spanish) predict self-rated health status for Texas residents of Hispanic ethnicity aged 18 to 64 years? " Key analysis variables were identified, and descriptive statistics were used to describe the major variables and determine whether the number of respondents for each variable was sufficient for analysis. Multivariate regression analysis was used to assess the variables. Results Multiple logistic regression analysis (controlling for diabetes and arthritis) of the self-rated health predictors indicated that older age, lack of health care coverage, lack of a college education, being Hispanic, having a lower income, obesity, and not exercising explained 19.4% of the variance of fair and poor self-rated health. The interview language (English or Spanish), age, sex, education, income, obesity, health insurance coverage, and physical activity (controlling for chronic illness) explained 22.8% of the variance in fair and poor self-rated health for Hispanic respondents. Conclusion The results of this study suggest that a college education, a lower body mass index, non-Hispanic ethnicity, and participation in physical activity are associated with good, very good, or excellent self-rated health status. The finding that the interview language significantly predicted fair and poor self-rated health substantiates previous research and emphasizes the importance of culturally sensitive approaches to health care services.
The BDNF Val 66 Met polymorphism moderates early deprivation effects on attention problems

Adverse early care is associated with attention regulatory problems, but not all so exposed develop attention problems. In a sample of 612 youth (girls=432, M=11.82 yrs, SD=1.5) adopted from institutions (e.g., orphanages) in 25 countries, we examined whether the Val66Met polymorphism of the BDNF gene moderates attention problems associated with the duration of institutional care. Parent-reported attention problem symptoms were collected using the MacArthur Health and Behavior Questionnaire. DNA was genotyped for the BDNF Val66Met (rs6265) SNP. Among youth from SE Asia, the predominant genotype was Val/Met, while among youth from Russia/ Europe and Caribbean/South America the predominant genotype was Val/Val. For analysis, youth were grouped as carrying Val/Val or AnyMet alleles. Being female, being from SE Asia, and being younger when adopted were associated with fewer attention regulatory problem symptoms. Youth carrying at least one copy of the Met allele were more sensitive to the duration of deprivation, yielding an interaction that followed a differential susceptibility pattern. Thus, youth with Val/Met or Met/Met genotypes exhibited fewer symptoms than Val/Val genotypes when adoption was very early and more symptoms when adoption occurred later in development. Similar patterns were observed when SE Asian youth and youth from other parts of the world were analyzed separately.
Cultural adaptation, compounding vulnerabilities and conjunctures in Norse Greenland

Norse Greenland has been seen as a classic case of maladaptation by an inflexible temperate zone society extending into the arctic and collapse driven by climate change. This paper, however, recognizes the successful arctic adaptation achieved in Norse Greenland and argues that, although climate change had impacts, the end of Norse settlement can only be truly understood as a complex socioenvironmental system that includes local and interregional interactions operating at different geographic and temporal scales and recognizes the cultural limits to adaptation of traditional ecological knowledge. This paper is not focused on a single discovery and its implications, an approach that can encourage monocausal and environmentally deterministic emphasis to explanation, but it is the product of sustained international interdisciplinary investigations in Greenland and the rest of the North Atlantic. It is based on data acquisitions, reinterpretation of established knowledge, and a somewhat different philosophical approach to the question of collapse. We argue that the Norse Greenlanders created a flexible and successful subsistence system that responded effectively to major environmental challenges but probably fell victim to a combination of conjunctures of large-scale historic processes and vulnerabilities created by their successful prior response to climate change. Their failure was an inability to anticipate an unknowable future, an inability to broaden their traditional ecological knowledge base, and a case of being too specialized, too small, and too isolated to be able to capitalize on and compete in the new protoworld system extending into the North Atlantic in the early 15th century.
Initial Clinical Experience with Robotic Lateral Pelvic Lymph Node Dissection for Advanced Rectal Cancer

Purpose This study was conducted to evaluate the technical feasibility and safety of robotic extended lateral pelvic lymph node dissection (LPLD) in patients with advanced low rectal cancer. Methods A review of a prospectively-collected database at Kyungpook National University Medical Center from January 2011 to November revealed a series of 8 consecutive robotic LPLD cases with a preoperative diagnosis of lateral node metastasis. Data regarding patient demographics, operating time, perioperative blood loss, surgical morbidity, lateral lymph node status, and functional outcome were analyzed. Results In all eight patients, the procedures were completed without conversion to open surgery. The mean operative time of extended pelvic node dissection was 38 minutes (range, 20 to 51 minutes), the mean number of lateral lymph nodes harvested was 4.1 (range, 1 to 13), and 3 patients (38%) were found to have lymph node metastases. Postoperative mortality and morbidity were 0% and 25%, respectively, but, there was no LPLD-related morbidity. The mean hospital stay was 7.5 days (range, 5 to 12 days). Conclusion Robotic LPLD is safe and feasible, with the advantage of being a minimally invasive approach. Further large-scale studies comparing robotic and conventional surgery with long-term follow-up evaluation are needed to confirm these findings.
Overexpression of HMGB 2 is associated with tumor aggressiveness and prognosis of hepatocellular carcinoma

Jung-Hee Kwon, Jongmin Kim, Jin Young Park, Sun Mi Hong, Chang Wook Park , Seok Joo Hong, Sun Young Park, Yoon Jung Choi, In-Gu Do, Jae-Won Joh, Dae Shick Kim, Kwan Yong Choi Department of Life Science, Pohang University of Science and Technology, Pohang 790-784, Korea; CbsBioscience, Inc., 59-5 Jang-Dong, Yuseong-gu, Daejeon 305-343, Korea; Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Goyang-city, Gyeonggi-do 410-719, Korea; Department of Pathology, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea
Tai Chi Chuan in Medicine and Health Promotion

Tai Chi Chuan (Tai Chi) is a Chinese traditional mind-body exercise and recently, it becomes popular worldwide. During the practice of Tai Chi, deep diaphragmatic breathing is integrated into body motions to achieve a harmonious balance between body and mind and to facilitate the flow of internal energy (Qi). Participants can choose to perform a complete set of Tai Chi or selected movements according to their needs. Previous research substantiates that Tai Chi has significant benefits to health promotion, and regularly practicing Tai Chi improves aerobic capacity, muscular strength, balance, health-related quality of life, and psychological well-being. Recent studies also prove that Tai Chi is safe and effective for patients with neurological diseases (e.g., stroke, Parkinson's disease, traumatic brain injury, multiple sclerosis, cognitive dysfunction), rheumatological disease (e.g., rheumatoid arthritis, ankylosing spondylitis, and fibromyalgia), orthopedic diseases (e.g., osteoarthritis, osteoporosis, low-back pain, and musculoskeletal disorder), cardiovascular diseases (e.g., acute myocardial infarction, coronary artery bypass grafting surgery, and heart failure), chronic obstructive pulmonary diseases, and breast cancers. Tai Chi is an aerobic exercise with mild-to-moderate intensity and is appropriate for implementation in the community. This paper reviews the existing literature on Tai Chi and introduces its health-promotion effect and the potential clinical applications.
Perceived Low Self-Actualization and External Fatalistic Determinism as a Function of Aging

Abstract This paper reports the results of research which tested for perceived differences in the locus of control orientation among the elderly. Two samples of institutionalized and noninstitutionalized men and women (N = 48), 64 to 90 years of age, were examined with respect to self-actualization and internal-external locus of control tendencies. The experimental group of 24 preselected Ss were interviewed in a nursing home; the remaining 24 Ss were interviewed in their own homes. The results suggest that a substantial difference in self-actualization and social control tendencies existed between the two groups. Both the institutionalized and noninstitutionalized group members were found to score lower than the standardized norm on self-actualization and the internal dimension; however, the institutionalized Ss recorded consistently lower scores on both self-actualization and internal locus of control than did those of the control group. Additionally, members of both groups were found to be high on the .
Emotional exhaustion in day-care workers

Although childcare workers have the second-worst occupation for work-related health problems and the number of professional day-care centers is growing throughout Europe, few studies have examined these workers’ emotional well-being. This study investigates the effect of position, competence, work role, role clarity, and work tasks on emotional exhaustion (EE) in a sample of almost 2500 Norwegian day-care center employees, representing 588 centers. We expected that preschool teachers would report higher levels of EE than assistants; role clarity, being confident in work role, and having a sense of co-worker support would correlate negatively with EE; and administrative tasks would correlate with higher levels of EE. We found that preschool teachers did display higher levels of EE until the work tasks were included. Competence, work role, and support were correlated negatively as expected. Parent-oriented tasks and teaching tasks were correlated with higher levels of EE.
Direct execution of OLSR MANET routing daemon in ns-3

Direct code execution framework recently developed for ns-3 is tested running open source OLSR implementation. It is shown that current DCE version is capable to run the unmodified production quality MANET routing daemon. Native ns-3 OLSR model is calibrated against DCE with rather didactic results. Finally, large-scale topologies are used for model and DCE comparison. The conclusion about the applicability areas of modeling and direct code execution are given.
Bridging the divide in work and organizational psychology: evidence from practice

This study explores the extent to which work and organizational (W&O) psychology practitioners use evidence, how they apply it to the everyday contexts in which they work, and the types of barriers they encounter in so doing. It adopts a mixed methods approach involving the administration of a survey to a UK sample (N = 163) of W&O psychologists and a series of semi-structured interviews (N = 25) exploring in greater depth how evidence is applied in practice. Findings reveal that practitioners consult a wide range of different types of evidence which they employ at various stages of engagement with client organizations and that this evidence is pressed into service in the pursuit of solutions which are both acceptable from the client perspective and consistent with the scientific standards underpinning professional knowledge and expertise in W&O psychology. Barriers to evidence-use were mainly practical in nature, concerning issues around managing the client–consultant relationship and the particularities of implementation context, both of which were shown to influence evidence utilization. The study contributes to current debate on the extent to which W&O psychologists adopt an evidence-based approach and provides a valuable and much called-for empirical insight into the enactment of the scientist–practitioner model in W&O psychology.
Evaluating the Utilisation of Mobile Devices in Online Payments from the Consumer Perspective

This paper presents empirical results of a study intended to evaluate the use of mobile devices for online payments. The mobile device can be used as an assistance device to increase consumer use of online payment systems. The data reported in this study was collected by surveying participant opinions in a free simulation experiment of mobile payment attributes. The study adopted some factors that were developed specifically for this research and some attributes reported in the literature as success factors in determining consumers’ acceptance of mobile payment systems. It was argued that the success of a mobile payment system needed to be considered from the consumer viewpoint. From this perspective, the scales used to measure the study attributes were adapted for use by consumers within the specified simulated experiment. Frequency percentage analysis was also used to examine factors that could affect mobile payment success. Consequential results from this study supported the use of mobile devices for online payments. The results showed that the use of mobile devices for online payments had a positive effect on persuading consumers to use online payments. The results also showed that such utilisation significantly increased the degree of consumer trust in online payments.
Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells

Modified mRNA vaccines have developed into an effective and well-tolerated vaccine platform that offers scalable and precise antigen production. Nevertheless, the immunological events leading to strong antibody responses elicited by mRNA vaccines are largely unknown. In this study, we demonstrate that protective levels of antibodies to hemagglutinin were induced after two immunizations of modified non-replicating mRNA encoding influenza H10 encapsulated in lipid nanoparticles (LNP) in non-human primates. While both intradermal (ID) and intramuscular (IM) administration induced protective titers, ID delivery generated this response more rapidly. Circulating H10-specific memory B cells expanded after each immunization, along with a transient appearance of plasmablasts. The memory B cell pool waned over time but remained detectable throughout the 25-week study. Following prime immunization, H10-specific plasma cells were found in the bone marrow and persisted over time. Germinal centers were formed in vaccine-draining lymph nodes along with an increase in circulating H10-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells, a population shown to correlate with high avidity antibody responses after seasonal influenza vaccination in humans. Collectively, this study demonstrates that mRNA/LNP vaccines potently induce an immunological repertoire associated with the generation of high magnitude and quality antibodies.