Miracle-dz/UniFAR-FTUs huggingface dataset:
DUALSIM: Parallel Subgraph Enumeration in a Massive Graph on a Single Machine

Subgraph enumeration is important for many applications such as subgraph frequencies, network motif discovery, graphlet kernel computation, and studying the evolution of social networks. Most earlier work on subgraph enumeration assumes that graphs are resident in memory, which results in serious scalability problems. Recently, efforts to enumerate all subgraphs in a large-scale graph have seemed to enjoy some success by partitioning the data graph and exploiting the distributed frameworks such as MapReduce and distributed graph engines. However, we notice that all existing distributed approaches have serious performance problems for subgraph enumeration due to the explosive number of partial results. In this paper, we design and implement a disk-based, single machine parallel subgraph enumeration solution called DualSim that can handle massive graphs without maintaining exponential numbers of partial results. Specifically, we propose a novel concept of the dual approach for subgraph enumeration. The dual approach swaps the roles of the data graph and the query graph. Specifically, instead of fixing the matching order in the query and then matching data vertices, it fixes the data vertices by fixing a set of disk pages and then finds all subgraph matchings in these pages. This enables us to significantly reduce the number of disk reads. We conduct extensive experiments with various real-world graphs to systematically demonstrate the superiority of DualSim over state-of-the-art distributed subgraph enumeration methods. DualSim outperforms the state-of-the-art methods by up to orders of magnitude, while they fail for many queries due to explosive intermediate results.
Successful Conversion From Parenteral Paricalcitol to Pulse Oral Calcitriol for the Management of Secondary Hyperparathyroidism in Hemodialysis Patients.

OBJECTIVE The management of hyperparathyroidism in hemodialysis patients involves the administration of phosphate binders, vitamin D receptor activators, and calcimimetics. Intravenous paricalcitol has been preferred over oral calcitriol as it may cause less hypercalcemia and hyperphosphatemia. However, there is little data looking at the efficacy and tolerability of oral calcitriol in the calcimimetic era particularly in a real practice-based experience. The University of California, Irvine free-standing dialysis center converted from routine intravenous paricalcitol to oral calcitriol due to pharmacy purchasing preferences. We report the efficacy, safety, and cost of such a change. SUBJECTS Ninety-three preconversion intravenous paricalcitol and 91 postconversion oral calcitriol. INTERVENTION Conversion to in-center, pulse, oral calcitriol (0.25 mcg = 1 mcg paricalcitol) 3 times a week from intravenous paricalcitol. Additional dose adjustments were made by the nephrologists based on clinical indications. MAIN OUTCOME MEASURE Five-month average serum calcium, phosphorous, and intact parathyroid hormone levels and cardiovascular events pretransition and posttransition. RESULTS There were 93 patients on intravenous paricalcitol between April 2013 and August 2013, of which 74 converted to oral calcitriol and were included in the postconversion group evaluated between October 2013 and February 2014. An additional 17 new patients had initiated calcitriol such that 91 patients were on oral therapy in the postconversion period. Sevelamer use increased from 41 (44.1%) patients preconversion to 48 (52.7%) postconversion, whereas calcium acetate use significantly dropped from 62 (66.7%) to 46 (50.5%) (P = .026). Cinacalcet use dropped slightly from 37 (39.7%) patients preconversion to 35 (38.4%) postconversion. Average serum calcium, phosphorus, and intact parathyroid hormone levels remained unchanged after conversion. Percent of values within Kidney Disease Outcome Quality Initiative guidelines were similarly maintained. Estimated vitamin D cost savings were $564 per person/year. No increase in the incidence of cardiovascular events was observed. CONCLUSIONS We conclude that in-center distributed pulse oral calcitriol may be an effective, safe, and economical treatment option for the management of hyperparathyroidism in hemodialysis patients.
UAV-Enabled Mobile Edge Computing: Offloading Optimization and Trajectory Design

With the emergence of diverse mobile applications (such as augmented reality), the quality of experience of mobile users is greatly limited by their computation capacity and finite battery lifetime. Mobile edge computing (MEC) and wireless power transfer are promising to address this issue. However, these two techniques are susceptible to propagation delay and loss. Motivated by the chance of short-distance line-of-sight achieved by leveraging unmanned aerial vehicle (UAV) communications, an UAV-enabled wireless powered MEC system is studied. A power minimization problem is formulated subject to the constraints on the number of the computation bits and energy harvesting causality. The problem is non-convex and challenging to tackle. An alternative optimization algorithm is proposed based on sequential convex optimization. Simulation results show that our proposed design is superior to other benchmark schemes and the proposed algorithm is efficient in terms of the convergence.
Management of Elevated Therapeutic Impedances on Deep Brain Stimulation Leads

Clinical Vignette A 64-year-old male with a history of essential tremor with bilateral thalamic ventralis intermedius deep brain stimulation implants had elevated therapeutic impedance values despite normal lead integrity impedances and good response to stimulation. Clinical Dilemma Do elevated therapeutic impedance values indicate a sign of hardware malfunction? What are the guidelines to approach deep brain stimulation hardware malfunction? Clinical Solution Lead integrity impedance values are a better evaluation of hardware integrity. The discrepancy between therapeutic and lead-integrity impedance values can arise when using low voltage settings. Gaps in Knowledge There are no established guidelines for the management of possible hardware malfunction in deep brain stimulation. The recommended approach is to distinguish between open and short circuit problems followed by an “inching” evaluation, assessing the structures from the implantable and programmable generator to the intracranial leads. Constant-current devices will deliver a more stable stimulation but the effect of their adoption is still not clear. Expert Commentary This case emphasizes the need for clinicians to understand fundamental differences in lead integrity and therapeutic impedance while utilizing a methodical approach in treating hardware malfunction. It highlights future avenues of investigation regarding the utility of constant current DBS technology.
Optimal routing for UWB-based sensor networks

This paper considers ultra-wideband (UWB)-based sensor networks and studies the following problem: given a set of source sensor nodes in the network each generating a certain data rate, is it possible to relay all these rates successfully to the base station? We will show that such problem is intrinsic cross-layer, and subsequently we formulate an optimization problem, with joint consideration of link-layer scheduling, power control, and network-layer routing. For large-sized networks, we propose an efficient heuristic algorithm by partitioning the given network into a core centered around the base station and a boundary edge. For the network core, we formulate a nonlinear programming problem, which can be solved by branch-and-bound approach. For data generated at network edge, we propose an algorithm to connect it to the network core. We use simulation results to demonstrate the efficacy of the proposed solution procedure, as well as the importance of cross-layer considerations.
Precipitation behavior of σ phase in UNS S32760 super duplex stainless steel

Precipitation behavior of σ phase in UNS S32760 super duplex stainless steel sheet after solution treating at 1100 ℃ for 60 min and followed by aging treatment at temperature from 760 ℃ to 1040 ℃ for 30 min was investigated by means of optical microscopy( OM),nano-indentation tests,scanning electron microscopy( SEM),energy dispersive spectrometer( EDS) analysis and transmission electron microscopy( TEM). The effect of W on the precipitation behavior was analyzed. The results show that σ phase is rich in Cr,Mo,W,poor in Ni and no N element contained. The stability of σ phase can be improved by W,leading to σ phase precipitation in a wide range from760 ℃ to 1020 ℃. The hardness of the sheet reaches its maximum value of 37. 1 HRC and the ferrite volume fraction decreases to 5. 3%after aging at the nose temperature of 880 ℃ for 30 min. With aging temperature increasing,the morphology of σ phase changes from granular to granular and short bar,further to eutectoid structure and finally block. Eutectoid σ phase and γ2phase are precipitated near the nose temperature( 880 ℃),while the morphology of γ2phase surrounded by σ phase appears at higher aging temperature( 960 ℃).
Selectivity and sensitivity enhancement methods for high‐data‐rate super‐regenerative receiver

This paper describes selectivity and sensitivity performance evaluations and improvement methods for an on–off keying super‐regenerative (SR) receiver. A slope‐controlled quasi‐exponential quench waveform, generated by a low‐complexity PVT‐tolerant quench generator circuit, is proposed to increase data rate and reduce the receiver 3‐dB bandwidth, thereby preventing oscillation caused by out‐of‐band injected signals and improving the receiver selectivity. The SR receiver sensitivity is also enhanced by a noise‐canceling front‐end topology with single‐ended to differential (S2D) signal converter. To exemplify these techniques, we designed an SR receiver with the proposed front‐end and quench waveform generator in a 0.18‐μm CMOS technology. Theoretical analyses and circuit simulations show 30% and 65% reduction in 3‐dB bandwidth of the SR receiver at 25 Mbps data rate by employing the proposed quench signal compared with piecewise‐linear and trapezoidal quench waveforms, respectively. Performance of the proposed front‐end is evaluated by a fast bit‐error‐rate estimation procedure, based on circuit noise simulations and statistical analyses, without the need for time‐consuming transient‐noise simulations. Accuracy of the procedure has been verified by comparing its results with transient‐noise simulations. According to the estimated bit‐error‐rate curves, the noise‐canceling topology with S2D converter enhances the SR receiver sensitivity by 9 dB. Copyright © 2017 John Wiley & Sons, Ltd.
Influence of single-trial results on clinical practice: example of adenotonsillectomy in children.

OBJECTIVE To establish whether the results of a 2004 trial on the effectiveness of adenotonsillectomy in children with mild to moderate symptoms of throat infection or adenotonsillar hypertrophy affected physicians' beliefs about the benefits of the operation and influenced clinical practice. DESIGN Prospective prior-posterior study. SETTING Academic research. PARTICIPANTS We evaluated beliefs prior and posterior to the 2004 trial regarding the benefits of adenotonsillectomy in a random sample of 120 Dutch otolaryngologists and 120 Dutch general practitioners. MAIN OUTCOME MEASURE Physicians were asked to give their estimates of the probability of recovery during 1 year after adenotonsillectomy or a nonsurgical strategy in 3 scenarios of children aged 3 to 4 years with recurrent throat infection, upper respiratory tract infection (with or without fever), or sleep-related breathing disorder. RESULTS Ninety-four percent of otolaryngologists (n = 46) and 31% of general practitioners (n = 14) were familiar with the 2004 trial results. Posterior beliefs of otolaryngologists and general practitioners did not differ substantially from prior beliefs; overall expectations regarding the benefits of adenotonsillectomy remained high. CONCLUSION Dissemination of the 2004 trial results did not seem to affect the beliefs of physicians regarding the benefits of adenotonsillectomy. TRIAL REGISTRATION isrctn.org Identifier: ISRCTN04973569.
Combined Analysis of Extant Rhynchonellida (Brachiopoda) using Morphological and Molecular Data

Abstract. Independent molecular and morphological phylogenetic analyses have often produced discordant results for certain groups which, for fossil‐rich groups, raises the possibility that morphological data might mislead in those groups for which we depend upon morphology the most. Rhynchonellide brachiopods, with more than 500 extinct genera but only 19 extant genera represented today, provide an opportunity to explore the factors that produce contentious phylogenetic signal across datasets, as previous phylogenetic hypotheses generated from molecular sequence data bear little agreement with those constructed using morphological characters. Using a revised matrix of 66 morphological characters, and published ribosomal DNA sequences, we performed a series of combined phylogenetic analyses to identify conflicting phylogenetic signals. We completed a series of parsimony‐based and Bayesian analyses, varying the data used, the taxa included, and the models used in the Bayesian analyses. We also performed simulation‐based sensitivity analyses to assess whether the small size of the morphological data partition relative to the molecular data influenced the results of the combined analyses. In order to compare and contrast a large number of phylogenetic analyses and their resulting summary trees, we developed a measure for the incongruence between two topologies and simultaneously ignore any differences in phylogenetic resolution. Phylogenetic hypotheses generated using only morphological characters differed among each other, and with previous analyses, whereas molecular‐only and combined Bayesian analyses produced extremely similar topologies. Characters historically associated with traditional classification in the Rhynchonellida have very low consistency indices on the topology preferred by the combined Bayesian analyses. Overall, this casts doubt on the use of morphological systematics to resolve relationships among the crown rhynchonellide brachiopods. However, expanding our dataset to a larger number of extinct taxa with intermediate morphologies is necessary to exclude the possibility that the morphology of extant taxa is not dominated by convergence along long branches.
Multiple Intussusceptions Associated with Polycythemia in an Anabolic Steroid Abuser, A Case Report and Literature Review

Intussusceptions are generally associated with mechanical lead points or localized inflammation that function as foci for intestinal telescoping. We present the case of a patient whose abuse of anabolic steroids resulted in the development of multiple simultaneous intussusceptions. Our patient had no additional identifiable risk factors for intussusception. Consistent with previous reports, corticosteroid induced polycythemia and its consequent hyperviscosity led to intravascular sludging and mesenteric ischemia with associated bowel wall thickening. The localized intestinal induration then served as mechanical foci for intussusception. Due to the illicit nature of anabolic androgenic steroid (AAS) abuse, the physiologic effects of supraphysiologic doses are sparsely reported and poorly understood. The scope of AAS abuse and its consequences are likely under-reported and under-recognized within the medical community. Our case presented a unique diagnostic and therapeutic challenge with which we aim to increasing awareness and clinical suspicion for AAS among healthcare personnel.
Feasibility and Utility of Online Dementia Care Training for Hospital Staff: The CARES® Dementia-Friendly Hospital™ Program.

The current project tested the feasibility and utility of the CARES® Dementia-Friendly Hospital™ (CDFH) program, a 4-module, online training program for nursing assistants (NAs) and allied hospital workers (AHWs) who provide care to individuals with dementia. A single group pretest/posttest design was used for 25 hospital NAs/AHWs, and quantitative and qualitative data were collected to determine whether NAs'/AHWs' knowledge of hospital-based dementia care significantly increased, and if CDFH was perceived as useful and acceptable. Dementia care knowledge increased significantly (p < 0.001). Open- and closed-ended data suggested that the delivery of online training to NAs/AHWs to enhance dementia care is feasible, useful, and efficient. Ongoing gaps in care exist for individuals with dementia in hospitals, and delivering robust training for NAs/AHWs may serve as an effective modality to enhance quality of dementia care in such settings. [Res Gerontol Nurs. 2017; 10(2):58-65. ].
Back to Sports After Arthroscopic Revision Bankart Repair

Background: Recurrent instability following primary arthroscopic stabilization of the shoulder is a common complication. Young, athletic patients are at the greatest risk of recurring instability. To date, the literature contains insufficient description regarding whether return to sports is possible after revision arthroscopic Bankart repair. Hypothesis: Patients presenting with recurrent instability after primary arthroscopic stabilization should expect limitations in terms of their ability to partake in sporting activities after revision surgery. Study Design: Case series; Level of evidence, 4. Methods: Twenty athletes who underwent arthroscopic revision stabilization of the shoulder after failed primary arthroscopic Bankart repair were included in the study after completing inclusion and exclusion criteria surveys. Athletic Shoulder Outcome Scoring System (ASOSS), Shoulder Sport Activity Score (SSAS), and the Subjective Patient Outcome for Return to Sports (SPORTS) scores were determined to assess the participants’ ability to partake in sporting activities. Furthermore, sport type and sport level were classified and recorded. To assess function and stability, Rowe, American Shoulder and Elbow Surgeons, Constant-Murley, and Walch-Duplay scores were measured and recorded. Results: Follow-up consultations were carried out after a mean of 28.7 months. The mean age at follow-up examination was 27.75 years. At the time of follow-up, 70% of the patients were able to return to their original sporting activities at the same level. However, 90% of patients described a limitation in their shoulder when participating in their sports. At 28.7 months after surgery, the mean ASOSS score was 76.8; the SSAS score decreased from 7.85 before first-time dislocation to 5.35 at follow-up (P < .005). The SPORTS score was 5.2 out of 10 at the follow-up consultation. Function- and instability-specific scores showed good to excellent results. The mean external rotational deficit for high external rotation was 9.25°, and for low external rotation it was 12°. Conclusion: Patients can return to their original type and level of sport after arthroscopic revision Bankart repair, but they must expect persistent deficits and limitations to the shoulder when put under the strains of sporting activity. Patients with shoulder injuries who partake in sports that put greater demand on the shoulder show the smallest probabilities of returning to sporting activity.
Harms of cervical cancer screening in the United States and the Netherlands

We studied harms related to cervical cancer screening and management of screen‐positive women in the United States (US) and the Netherlands. We utilized data from four US integrated health care systems (SEARCH), the US National Health Interview Survey, New Mexico state, the Netherlands national histopathology registry, and included studies on adverse health effects of cervical screening. We compared the number of Papanicolaou (Pap) smear tests, abnormal test results, punch biopsies, treatments, health problems (anxiety, pain, bleeding and discharge) and preterm births associated with excisional treatments. Results were age‐standardized to the 2007 US population. Based on SEARCH, an estimated 36 million Pap tests were performed in 2007 for 91 million US women aged 21–65 years, leading to 2.3 million abnormal Pap tests, 1.5 million punch biopsies, 0.3 million treatments for precancerous lesions, 5 thousand preterm births and over 8 million health problems. Under the Netherlands screening practice, fewer Pap tests (58%), abnormal test results (64%), punch biopsies (75%), treatment procedures (40%), preterm births (60%) and health problems (63%) would have occurred. The SEARCH data did not differ much from other US data for 2007 or from more recent data up to 2013. Thus compared to the less intensive screening practice in the Netherlands, US practice of cervical cancer screening may have resulted in two‐ to threefold higher harms, while the effects on cervical cancer incidence and mortality are similar. The results are also of high relevance in making recommendations for HPV screening. Systematic collection of harms data is needed for monitoring and for better incorporation of harms in making screening recommendations.
Sensitivity of Erythemally Effective UV Irradiance and Daily Exposure to Temporal Variability in Total Ozone

The provision of information to the public about current levels of the erythemally effective UV radiation is an important issue in health care. The quality of promoted values is therefore of special importance. The atmospheric parameter which affects the erythemally effective UV radiation under clear sky most is the total ozone content of the atmosphere. In this paper we examined the sensitivity of the erythemally effective irradiance and daily radiant exposure to the temporal variability of total ozone on time scales from 1 to 15 days. The results show that the sensitivity is highest for the first 24 h. Larger time scales do not exhibit a similar influence. Total ozone measurements of the previous day may already cause uncertainties higher than 0.5 UV index (UVI) independent of the geolocation. For comparison, a temporal persistence of 15 days may cause uncertainties of 1.2 UVI at 50°N, 1 UVI at 30°S and less than 1 UVI at the equator. The results of this study allow finding the necessary temporal resolution of total ozone values when a certain accuracy for the UVI or for the purpose of sun protection is required. The results are compared with those of two preceding studies where we quantified the influence of measurement uncertainties and spatial total ozone variability to the erythemally effective irradiance at noon and to the daily dose. We conclude that temporal variability of total ozone is the most critical issue, but also measurement uncertainties do have a noticeable influence on the erythemally effective radiation.
Parent Praise to Toddlers Predicts Fourth Grade Academic Achievement via Children’s Incremental Mindsets

In a previous study, parent–child praise was observed in natural interactions at home when children were 1, 2, and 3 years of age. Children who received a relatively high proportion of process praise (e.g., praise for effort and strategies) showed stronger incremental motivational frameworks, including a belief that intelligence can be developed and a greater desire for challenge, when they were in 2nd or 3rd grade (Gunderson et al., 2013). The current study examines these same children’s (n = 53) academic achievement 1 to 2 years later, in 4th grade. Results provide the first evidence that process praise to toddlers predicts children’s academic achievement (in math and reading comprehension) 7 years later, in elementary school, via their incremental motivational frameworks. Further analysis of these motivational frameworks shows that process praise had its effect on fourth grade achievement through children’s trait beliefs (e.g., believing that intelligence is fixed vs. malleable), rather than through their learning goals (e.g., preference for easy vs. challenging tasks). Implications for the socialization of motivation are discussed.