Miracle-dz/UniFAR-FTUs huggingface dataset:
Uncovering network tarpits with degreaser

Network tarpits, whereby a single host or appliance can masquerade as many fake hosts on a network and slow network scanners, are a form of defensive cyber-deception. In this work, we develop degreaser, an efficient fingerprinting tool to remotely detect tarpits. In addition to validating our tool in a controlled environment, we use degreaser to perform an Internet-wide scan. We discover tarpits of non-trivial size in the wild (prefixes as large as/16), and characterize their distribution and behavior. We then show how tarpits pollute existing network measurement surveys that are tarpit-naïve, e.g. Internet census data, and how degreaser can improve the accuracy of such surveys. Lastly, our findings suggest several ways in which to advance the realism of current network tarpits, thereby raising the bar on tarpits as an operational security mechanism.
Deciphering principles of morphogenesis from temporal and spatial patterns on the integument

Background: How tissue patterns form in development and regeneration is a fundamental issue remaining to be fully understood. The integument often forms repetitive units in space (periodic patterning) and time (cyclic renewal), such as feathers and hairs. Integument patterns are visible and experimentally manipulatable, helping us reveal pattern formative processes. Variability is seen in regional phenotypic specificities and temporal cycling at different physiological stages. Results: Here we show some cellular/molecular bases revealed by analyzing integument patterns. (1) Localized cellular activity (proliferation, rearrangement, apoptosis, differentiation) transforms prototypic organ primordia into specific shapes. Combinatorial positioning of different localized activity zones generates diverse and complex organ forms. (2) Competitive equilibrium between activators and inhibitors regulates stem cells through cyclic quiescence and activation. Conclusions: Dynamic interactions between stem cells and their adjacent niche regulate regenerative behavior, modulated by multi‐layers of macro‐environmental factors (dermis, body hormone status, and external environment). Genomics studies may reveal how positional information of localized cellular activity is stored. In vivo skin imaging and lineage tracing unveils new insights into stem cell plasticity. Principles of self‐assembly obtained from the integumentary organ model can be applied to help restore damaged patterns during regenerative wound healing and for tissue engineering to rebuild tissues. Developmental Dynamics 244:905–920, 2015. © 2015 Wiley Periodicals, Inc.
Thermal infrared directional emissivity of powdered quartz

Thermal infrared directional emissivity of quartz was measured for several particle size ranges and packing fractions. The samples measured were (1) a polished quartz slab; (2) a 75–250 μm powdered quartz sample, cleansed of clinging fines; (3) a 0–75 μm powdered quartz sample, sifted into a fairy castle structure; and (4) the same sample compressed to minimize porosity. The spectra of the particulate samples showed a strong dependence on exitance angle, particle size and packing fraction. In addition, thermal gradient effects significantly affected the measured emissivity of the fine, sifted sample. The measured directional emissivity was modeled by first using Mie theory to calculate single-particle scattering properties of a quartz spheres of appropriate size at a single wavelength and radiative transfer theory to calculate the flux reflected from an optically thick, plane-parallel “atmosphere” composed of particles with these scattering properties. For the 75–250 μm sample, close packing of individual particles was accounted for by subtracting the diffraction contribution to the scattering cross section. These calculations are repeated wavelength-by-wavelength to determine the spectral directional hemispherical reflectance of the quartz sample. Kirchhoff s law was then used to obtain spectral directional emissivity. This model, which uses optical constants derived from widely used oscillator parameters for quartz, reproduces the directional emissivity spectrum of the large powdered quartz to better than 10%. However, model calculations for 0–75 μm particle size quartz were less successful. This could be due to the several approximations used in the model, or to a possible error in the oscillator parameters. More successful calculations based on different optical constants suggest that the widely used oscillator parameters may well be wrong.
Tephra studies in New Zealand: an historical review

The development of tephra studies in New Zealand may be divided into four main periods: Period 1, late 19th century to late 1920s; Period 2, late 1920s to early 1950s; Period 3, early 1950s to 1973; Period 4, 1973 to late 1980s. The important events and advances that characterise each of these periods, and their causes and influences, are described with reference to contemporary scientists and their publications. Period 1: determination by dendrochronol ogy of first numerical age of a prehistorical eruptive (Burrell Lapilli); first isopach map (Tarawera Tephra). Period 2: first tephra mapping in central North Island (for soil survey). Period 3: first use of I4C dating; establishment of late Quaternary tephrostratigraphic framework by 'hand-over-hand' mapping in central North Island and Taranaki; initial development of tephra 'fingerprinting' using laboratory methods; application of tephrochronol ogy to many disciplines. Period 4: revision and refinement of proximal stratigraphy, particularly in central TVZ calderas and on Mayor Island; extension of tephra mapping to distal regions, on and offshore, and to older deposits; advances in tephra correlation and dating methods; new tephrochronological applications; revolutionary studies of pyroclastic deposits for determining nature and effects of eruptions (physical volcanology and petrology); renewed awareness of volcanic hazards associated with tephra eruptions. The advances relate to indigenous, external, and 'individualistic' factors. They generally parallelled overseas trends but in some topics preceded or lagged behind them. Tephra studies, or "tephrology", may be regarded as having "come of age" early in the 1980s, about 100 years after the first tephrostratigraphic studies in New Zealand.
Antiproliferative Activity and Apoptosis Induction of Crude Extract and Fractions of Avicennia Marina

Objective(s): Regarding the presence of many active biological constituents in Avicennia marina, the present investigation was carried out to study cytotoxic activity of crude methanol leave extract and column chromatographic fractions of A. marina against MDA-MB 231 cell line (human breast cancer cell) and HEK (Human embryonic kidney cell) line. Materials and Methods: The anticancer activity of crude methanol extract and sub-fractions were evaluated, using MTT assay. The induction of apoptosis was determined by analyzing DNA fragmentation in breast cancer cells treated with active fraction of crude methanol extract using agarose gel electrophoresis. To investigate molecular mechanism of apoptosis, gene expression levels of p53 and Bcl-2 were measured using quantitative real time PCR. Results: Fraction 10 was the most active fraction and was detected with HPLC as luteolin. The 50% cell cytotoxic concentration (CC50) of crude methanol extract and luteolin was 250 and 28 µg/ml, respectively. This fraction was found to be an apoptotic agent against MDA-MB 231 cells, which leads to causing DNA fragmentation. The mRNA expression level of Bcl-2 and p53 was significantly decreased and increased respectively in cancer cells treated by luteolin. Conclusion: The results suggested that Luteolin isolated from Avicennia marina could probably induce apoptosis on breast cancer cell line by the regulation of p53 and Bcl-2 pathways.
Influence of common sedimentary structures on fluid flow in reservoir models

This study summarizes the state of the art of deriving detailed permeability-distribution models on the basis of cores, sidewall samples, and logs. Reservoir heterogeneities such as clay drapes and intercalations, cross-bedding, sand laminations, slumping and burrowing in various major depositional environments are examined. 30 refs.
The Role of the Right Prefrontal Cortex in Self-evaluation of the Face: A Functional Magnetic Resonance Imaging Study

Individuals can experience negative emotions (e.g., embarrassment) accompanying self-evaluation immediately after recognizing their own facial image, especially if it deviates strongly from their mental representation of ideals or standards. The aim of this study was to identify the cortical regions involved in self-recognition and self-evaluation along with self-conscious emotions. To increase the range of emotions accompanying self-evaluation, we used facial feedback images chosen from a video recording, some of which deviated significantly from normal images. In total, 19 participants were asked to rate images of their own face (SELF) and those of others (OTHERS) according to how photogenic they appeared to be. After scanning the images, the participants rated how embarrassed they felt upon viewing each face. As the photogenic scores decreased, the embarrassment ratings dramatically increased for the participant's own face compared with those of others. The SELF versus OTHERS contrast significantly increased the activation of the right prefrontal cortex, bilateral insular cortex, anterior cingulate cortex, and bilateral occipital cortex. Within the right prefrontal cortex, activity in the right precentral gyrus reflected the trait of awareness of observable aspects of the self; this provided strong evidence that the right precentral gyrus is specifically involved in self-face recognition. By contrast, activity in the anterior region, which is located in the right middle inferior frontal gyrus, was modulated by the extent of embarrassment. This finding suggests that the right middle inferior frontal gyrus is engaged in self-evaluation preceded by self-face recognition based on the relevance to a standard self.
Cell-to-cell movement of the CAPRICE protein in Arabidopsis root epidermal cell differentiation

CAPRICE (CPC), a small, R3-type Myb-like protein, is a positive regulator of root hair development in Arabidopsis. Cell-to-cell movement of CPC is important for the differentiation of epidermal cells into trichoblasts (root hair cells). CPC is transported from atrichoblasts (hairless cells), where it is expressed, to trichoblasts, and generally accumulates in their nuclei. Using truncated versions of CPC fused to GFP, we identified a signal domain that is necessary and sufficient for CPC cell-to-cell movement. This domain includes the N-terminal region and a part of the Myb domain. Amino acid substitution experiments indicated that W76 and M78 in the Myb domain are critical for targeted transport, and that W76 is crucial for the nuclear accumulation of CPC:GFP. To evaluate the tissue-specificity of CPC movement, CPC:GFP was expressed in the stele using the SHR promoter and in trichoblasts using the EGL3 promoter. CPC:GFP was able to move from trichoblasts to atrichoblasts but could not exit from the stele, suggesting the involvement of tissue-specific regulatory factors in the intercellular movement of CPC. Analyses with a secretion inhibitor, Brefeldin A, and with an rhd3 mutant defective in the secretion process in root epidermis suggested that intercellular CPC movement is mediated through plasmodesmata. Furthermore, the fusion of CPC to tandem-GFPs defined the capability of CPC to increase the size exclusion limit of plasmodesmata.
The role of radiation geometry in the climate response of mount kenya's glaciers, part 2: Sloping versus horizontal surfaces

This part of the study expands the modelling of incident solar radiation on Mount Kenya and its glaciers to include the behaviour for sloping as compared to horizontal surfaces. It is concluded that for the purposes of the ongoing climate study the broad-scale generalizations reached in part 1 of the study for horizontal reference surfaces remain inviolate for sloping reference surfaces. However, significant additional information is brought out by reference to sloping surfaces. Further, differences in absolute radiation magnitudes are significant for realistic situations of cloudiness and shading when modelling short-term (e.g. monthly) radiation means. In the annual case, these differences are small for glaciers having mean gradients up to 45°; for the one extremely steep glacier with mean slope approaching 60°, these differences are significant. It is anticipated that for higher latitudes the discrepancies between sloping and horizontal reference surfaces in the annual case may well be more substantial. For Mount Kenya, located as it is almost directly under the Equator, it must be concluded that the conventional horizontal reference surface is indeed appropriate for climatic heat and mass budget analyses.
Growth Culture Conditions and Nutrient Signaling Modulating Yeast Chronological Longevity

The manipulation of nutrient-signaling pathways in yeast has uncovered the impact of environmental growth conditions in longevity. Studies using calorie restriction show that reducing glucose concentration of the culture media is sufficient to increase replicative and chronological lifespan (CLS). Other components of the culture media and factors such as the products of fermentation have also been implicated in the regulation of CLS. Acidification of the culture media mainly due to acetic acid and other organic acids production negatively impacts CLS. Ethanol is another fermentative metabolite capable of inducing CLS reduction in aged cells by yet unknown mechanisms. Recently, ammonium was reported to induce cell death associated with shortening of CLS. This effect is correlated to the concentration of NH4 + added to the culture medium and is particularly evident in cells starved for auxotrophy-complementing amino acids. Studies on the nutrient-signaling pathways regulating yeast aging had a significant impact on aging-related research, providing key insights into mechanisms that modulate aging and establishing the yeast as a powerful system to extend knowledge on longevity regulation in multicellular organisms.
Endovascular Stent Placement for Hemodialysis Arteriovenous Access Stenosis

This study aims to report the outcomes of nitinol and polytetrafluoroethylene covered stent placement to treat hemodialysis arteriovenous access stenosis at a single center over a five-year period. Clinical and radiological information was reviewed retrospectively. Poststent primary and secondary patency rates were determined using Kaplan-Meier analysis. Ten clinical variables were subjected to multivariate Cox regression analysis to determine predictors of patency after stent placement. During the study period 60 stents were deployed in 45 patients, with a mean follow-up of 24.5 months. The clinical and anatomical success rate was 98.3% (59/60). Poststent primary patency rates at 6, 12, and 24 months were 64%, 46%, and 35%, respectively. Poststent secondary patency rates at 6, 12, and 24 months were 95%, 89%, and 85%, respectively. Stent placement for upper arm lesions and in access less than 12 months of age was associated with reduced primary patency (adjusted hazards ratio [HR] 5.1, p = 0.0084, and HR 3.5, p = 0.0029, resp.). Resistant or recurrent stenosis can be successfully treated by endovascular stent placement with durable long-term patency, although multiple procedures are often required. Stent placement for upper arm lesions and in arteriovenous access less than 12 months of age was associated with increased risk of patency loss.
Why Does Population Aging Matter So Much for Asia? Population Aging, Economic Security and Economic Growth in Asia

Asia as a whole is experiencing a rapid demographic transition toward older population structures. Within this broader region-wide trend, there is considerable heterogeneity, with different countries at different stages of the demographic transition. In this paper, we document Asia’s population aging, describe the region’s old-age support systems, and draw out the regional socioeconomic implications of population aging and old-age support systems. Population aging gives rise to two fundamental challenges for the region – (1) developing socioeconomic systems that can provide economic security to the growing number of elderly and (2) sustaining strong growth in the face of aging over the next few decades. Successfully addressing those two challenges will be vital for ensuring Asia’s continued economic success in the medium and long term.
Climbing‐ripple successions in turbidite systems: depositional environments, sedimentation rates and accumulation times

Climbing‐ripple cross‐lamination is most commonly deposited by turbidity currents when suspended load fallout and bedload transport occur contemporaneously. The angle of ripple climb reflects the ratio of suspended load fallout and bedload sedimentation rates, allowing for the calculation of the flow properties and durations of turbidity currents. Three areas exhibiting thick (>50 m) sections of deep‐water climbing‐ripple cross‐lamination deposits are the focus of this study: (i) the Miocene upper Mount Messenger Formation in the Taranaki Basin, New Zealand; (ii) the Permian Skoorsteenberg Formation in the Tanqua depocentre of the Karoo Basin, South Africa; and (iii) the lower Pleistocene Magnolia Field in the Titan Basin, Gulf of Mexico. Facies distributions and local contextual information indicate that climbing‐ripple cross‐lamination in each area was deposited in an ‘off‐axis’ setting where flows were expanding due to loss of confinement or a decrease in slope gradient. The resultant reduction in flow thickness, Reynolds number, shear stress and capacity promoted suspension fallout and thus climbing‐ripple cross‐lamination formation. Climbing‐ripple cross‐lamination in the New Zealand study area was deposited both outside of and within channels at an inferred break in slope, where flows were decelerating and expanding. In the South Africa study area, climbing‐ripple cross‐lamination was deposited due to a loss of flow confinement. In the Magnolia study area, an abrupt decrease in gradient near a basin sill caused flow deceleration and climbing‐ripple cross‐lamination deposition in off‐axis settings. Sedimentation rate and accumulation time were calculated for 44 climbing‐ripple cross‐lamination sedimentation units from the three areas using TDURE, a mathematical model developed by Baas et al. (2000) . For Tc divisions and Tbc beds averaging 26 cm and 37 cm thick, respectively, average climbing‐ripple cross‐lamination and whole bed sedimentation rates were 0·15 mm sec−1 and 0·26 mm sec−1 and average accumulation times were 27 min and 35 min, respectively. In some instances, distinct stratigraphic trends of sedimentation rate give insight into the evolution of the depositional environment. Climbing‐ripple cross‐lamination in the three study areas is developed in very fine‐grained to fine‐grained sand, suggesting a grain size dependence on turbidite climbing‐ripple cross‐lamination formation. Indeed, the calculated sedimentation rates correlate well with the rate of sedimentation due to hindered settling of very fine‐grained and fine‐grained sand–water suspensions at concentrations of up to 20% and 2·5%, respectively. For coarser grains, hindered settling rates at all concentrations are much too high to form climbing‐ripple cross‐lamination, resulting in the formation of massive/structureless S3 or Ta divisions.
Limitations of methods for measuring out-of-pocket and catastrophic private health expenditures.

OBJECTIVE To investigate the effect of survey design, specifically the number of items and recall period, on estimates of household out-of-pocket and catastrophic expenditure on health. METHODS We used results from two surveys--the World Health Survey and the Living Standards Measurement Study--that asked the same respondents about health expenditures in different ways. Data from the World Health Survey were used to compare estimates of average annual out-of-pocket spending on health care derived from a single-item and from an eight-item measure. This was done by calculating the ratio of the average obtained with the single-item measure to that obtained with the eight-item measure. Estimates of catastrophic spending from the two measures were also compared. Data from the Living Standards Measurement Study from three countries (Bulgaria, Jamaica and Nepal) with different recall periods and varying numbers of items in different modules were used to compare estimates of average annual out-of-pocket spending derived using various methods. FINDINGS In most countries, a lower level of disaggregation (i.e. fewer items) gave a lower estimate for average health spending, and a shorter recall period yielded a larger estimate. However, when the effects of aggregation and recall period are combined, it is difficult to predict which of the two has the greater influence. CONCLUSION The magnitude of both out-of-pocket and catastrophic spending on health is affected by the choice of recall period and the number of items. Thus, it is crucial to establish a method to generate valid, reliable and comparable information on private health spending.
Challenges and opportunities for water resources management in southeast Asia

Abstract The issues of water resources management are addressed with specific reference to the available water resources and water demand for the Chao Phraya River basin in Thailand. The water resources management practices in most of the countries in southeast Asia have been generally on a sectoral level without consideration of any intersectoral interference and trade-off. A change of paradigm is needed with a holistic approach giving due regard to the requirement of equitable distribution of water, adequate governance, efficient economic performance and maintenance of environmental quality. Technological intervention, probable institutional reforms, community participation, water conservation and re-use, water policy and legal frameworks are some of the feasible measures that provide opportunities to evolve a systematic approach to water resources management.