Miracle-dz/UniFAR-FTUs huggingface dataset:
A Window on the (Changing) Neighbourhood: The Role of Pubs in the Contested Spaces of Gentrification

This paper examines the effects of gentrification through the lens of the interactions and perceptions which can be found in local, neighbourhood pubs. By interviewing predominantly Dutch, non-gentrifying customers in the rapidly gentrifying Indische Buurt neighbourhood in Amsterdam, we uncovered discourses which are both welcoming to, and cautious of the process. Three themes were examined: changes in the neighbourhood, changes in the role of pubs in daily life and changes in the interactions within pubs. In many respects, the process of gentrification is welcomed because it represents something ‘Dutch’ coming into the neighbourhood after years of immigration. Divisions between gentrifiers and non-gentrifiers are not experienced as starkly as is often portrayed in the literature; our respondents tended to be much more ambivalent than other non-gentrifying groups portrayed in studies elsewhere. This may be due to the more managed-nature of Dutch gentrification. However, there is a sense that one's pub is impervious to the changes in the rest of the neighbourhood, a discourse which must be taken into account when drawing any long-term conclusions from this study.
Challenges in Multiple Cross-Sector Partnerships

This research examines challenges associated with partnerships among a group of cross-sector organizations. The context for this study is a nonprofit organization in Canada's sport system and its numerous partners in public, nonprofit, and commercial sectors. The results reveal challenges in the areas of structure and strategy. Specifically, data uncover structural challenges with respect to problems with governance, roles, and responsibilities guiding the partnerships and with the complexity of partnership forms and structures. The data also uncover strategic challenges, in light of the focus on competition versus collaboration among various partners and the changes in missions and objectives through the duration of the relationship. The results and implications for nonprofit organizations involved in multiple cross-sector partnerships are discussed.
A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus

In vitro infection by the human immunodeficiency virus (HIV) of CD4+ H9 lymphoblasts is inhibited by a mannose-binding protein (MBP) purified from human serum. In addition, MBP is able to selectively bind to HIV- infected H9 cells and HIV-infected cells from the monocyte cell line U937. These results indicate MBP most likely recognizes high mannose glycans known to be present on gp120 in the domain that is recognized by CD4 and thereby inhibits viral entry to susceptible cells. In support of this contention, recombinant gp120 binds directly to MBP; the binding is saturable, mannan inhibitable, removed by N-glycanase treatment, and dependent on divalent cations.
Use of Plant Extracts as an Effective Manner to Control Clostridium perfringens Induced Necrotic Enteritis in Poultry

Necrotic enteritis (NE) is an important concern in poultry industry since it causes economic losses, increased mortality, reduction of bird welfare, and contamination of chicken products for human consumption. For decades, the use of in-feed antimicrobial growth promoters (AGPs) has been the main strategy to control intestinal pathogens including Clostridium perfringens (CP), the causative agent of NE. However, the use of AGPs in animal diet has been linked to the emergence and transmission of antimicrobial resistance through food-borne microorganisms, which has led to the ban of AGPs in many countries. This scenario has challenged the poultry industry to search for safer alternative products in order to prevent NE. In this context, the utilization of natural plant extracts with antimicrobial properties appears as a promising and feasible tool to control NE in chicken. In this paper, we review the scientific studies analyzing the potential of plant extracts as alternative feed additives to reduce NE in poultry, with focus on two types of plant products that arise as promising candidates: tannins and essential oils. Some of these products showed antimicrobial activity against CP and coccidia in vitro and in vivo and are able to increase productive performance, emulating the bioactive properties of AGPs.
Evaluation of Rhamnetin as an Inhibitor of the Pharmacological Effect of Secretory Phospholipase A2

Rhamnetin (Rhm), 3-O-methylquercetin (3MQ), and Rhamnazin (Rhz) are methylated derivatives of quercetin commonly found in fruits and vegetables that possess antioxidant and anti-inflammatory properties. Phospholipase A2 (PLA2) displays several important roles during acute inflammation; therefore, this study aimed at investigating new compounds able to inhibit this enzyme, besides evaluating creatine kinase (CK) levels and citotoxicity. Methylated quercetins were compared with quercetin (Q) and were incubated with secretory PLA2 (sPLA2) from Bothrops jararacussu to determine their inhibitory activity. Cytotoxic studies were performed by using the J774 cell lineage incubated with quercertins. In vivo tests were performed with Swiss female mice to evaluate decreasing paw edema potential and compounds’ CK levels. Structural modifications on sPLA2 were made with circular dichroism (CD). Despite Q and Rhz showing greater enzymatic inhibitory potential, high CK was observed. Rhm exhibited sPLA2 inhibitory potential, no toxicity and, remarkably, it decreased CK levels. The presence of 3OH on the C-ring of Rhm may contribute to both its anti-inflammatory and enzymatic inhibition of sPLA2, and the methylation of ring A may provide the increase in cell viability and low CK level induced by sPLA2. These results showed that Rhm can be a candidate as a natural compound for the development of new anti-inflammatory drugs.
Large-Eddy Simulation of Pressure Transport Below the Mixed Layer

Deep convection energizes the entire water column. Large-eddy simulation of the oceanic boundary layer system predicts turbulence in the well-mixed layer as well as turbulence-induced internal waves propagating into the underlying stratified water column of the freely convecting wintertime Labrador Sea. Of particular interest is the downward propagation of energy from the turbulent boundary layer by pressure transport and the buildup of internal wave energy in response to local atmospheric forcing. A near equilibrium internal wave spectrum is approached after about two weeks of episodic storm cooling. A broad band omnidirectional internal wave field with peak energy near the buoyancy frequency N is forced mostly by the surface buoyancy flux. The pressure transport of mixed-layer kinetic energy carries about 30 % of the available energy into the stratified zone and causing entrainment. On average, 10 W/m or about 1% of the winter Labrador Sea mixed-layer energy escapes into the pycnocline where it is converted into internal wave energy.
TVD: A Reproducible and Multiply Aligned TV Series Dataset

We introduce a new dataset built around two TV series from different genres, The Big Bang Theory, a situation comedy and Game of Thrones, a fantasy drama. The dataset has multiple tracks extracted from diverse sources, including dialogue (manual and automatic transcripts, multilingual subtitles), crowd-sourced textual descriptions (brief episode summaries, longer episode outlines) and various metadata (speakers, shots, scenes). The paper describes the dataset and provide tools to reproduce it for research purposes provided one has legally acquired the DVD set of the series. Tools are also provided to temporally align a major subset of dialogue and description tracks, in order to combine complementary information present in these tracks for enhanced accessibility. For alignment, we consider tracks as comparable corpora and first apply an existing algorithm for aligning such corpora based on dynamic time warping and TFIDF-based similarity scores. We improve this baseline algorithm using contextual information, WordNet-based word similarity and scene location information. We report the performance of these algorithms on a manually aligned subset of the data. To highlight the interest of the database, we report a use case involving rich speech retrieval and propose other uses.
Porous Bead-Based Diagnostic Platforms: Bridging the Gaps in Healthcare

Advances in lab-on-a-chip systems have strong potential for multiplexed detection of a wide range of analytes with reduced sample and reagent volume; lower costs and shorter analysis times. The completion of high-fidelity multiplexed and multiclass assays remains a challenge for the medical microdevice field; as it struggles to achieve and expand upon at the point-of-care the quality of results that are achieved now routinely in remote laboratory settings. This review article serves to explore for the first time the key intersection of multiplexed bead-based detection systems with integrated microfluidic structures alongside porous capture elements together with biomarker validation studies. These strategically important elements are evaluated here in the context of platform generation as suitable for near-patient testing. Essential issues related to the scalability of these modular sensor ensembles are explored as are attempts to move such multiplexed and multiclass platforms into large-scale clinical trials. Recent efforts in these bead sensors have shown advantages over planar microarrays in terms of their capacity to generate multiplexed test results with shorter analysis times. Through high surface-to-volume ratios and encoding capabilities; porous bead-based ensembles; when combined with microfluidic elements; allow for high-throughput testing for enzymatic assays; general chemistries; protein; antibody and oligonucleotide applications.
Developmental Trajectories of Self-Control: Assessing the Stability Hypothesis

A key proposition of Gottfredson and Hirschi’s (1990) self-control theory is the stability hypothesis which suggests that an individual’s level of self-control, once established between the ages of 8-10, is stable over the life course. Empirical results from examinations of the stability hypothesis have been mixed. Prior tests of the stability hypothesis have employed aggregate assessment methods (e.g., mean-level and correlational analyses). Such approaches fail to take into account the possibility that individual developmental pathways may differ. This study employs individual longitudinal data over a four year period for 3,249 7 to 10 grade subjects to assess the stability hypothesis using both traditional stability estimation techniques (e.g., ANOVAs and zero-order correlations), as well as heterogeneity assessment methods – semiparametric group-based trajectory modeling (SPGM). Multinomial logistic regression (MLOGIT) of theoretically and empirically relevant risk factors (i.e., parenting, parental criminality, deviant peers, bonds to school) was employed to distinguish between developmental trajectories. SPGM results suggest that self-control is stable for a majority of the sample; however, a sizeable portion of the sample evinced trajectories for which self-control was marked by considerable change. Specifically, 6 unique trajectories in the development of self-control were identified – two groups were identified with high stable trajectories of self-control and four groups were identified that had lower, less stable trajectories of self-control. Additionally, several risk factors
Evolution of asexual reproduction in leaves of the genus Kalanchoë

Plant somatic cells have the remarkable ability to regenerate an entire organism. Many species in the genus Kalanchoë, known as “mother of thousands,” develop plantlets on the leaf margins. Using key regulators of organogenesis (STM) and embryogenesis (LEC1 and FUS3) processes, we analyzed asexual reproduction in Kalanchoë leaves. Suppression of STM abolished the ability to make plantlets. Here, we report that constitutive plantlet-forming species, like Kalanchoë daigremontiana, form plantlets by coopting both organogenesis and embryogenesis programs into leaves. These species have a defective LEC1 gene and produce nonviable seed, whereas species that produce plantlets only upon stress induction have an intact LEC1 gene and produce viable seed. The latter species are basal in the genus, suggesting that induced-plantlet formation and seed viability are ancestral traits. We provide evidence that asexual reproduction likely initiated as a process of organogenesis and then recruited an embryogenesis program into the leaves in response to loss of sexual reproduction within this genus.
Sensorimotor experience enhances automatic imitation of robotic action

Recent research in cognitive neuroscience has found that observation of human actions activates the ‘mirror system’ and provokes automatic imitation to a greater extent than observation of non-biological movements. The present study investigated whether this human bias depends primarily on phylogenetic or ontogenetic factors by examining the effects of sensorimotor experience on automatic imitation of non-biological robotic, stimuli. Automatic imitation of human and robotic action stimuli was assessed before and after training. During these test sessions, participants were required to execute a pre-specified response (e.g. to open their hand) while observing a human or robotic hand making a compatible (opening) or incompatible (closing) movement. During training, participants executed opening and closing hand actions while observing compatible (group CT) or incompatible movements (group IT) of a robotic hand. Compatible, but not incompatible, training increased automatic imitation of robotic stimuli (speed of responding on compatible trials, compared with incompatible trials) and abolished the human bias observed at pre-test. These findings suggest that the development of the mirror system depends on sensorimotor experience, and that, in our species, it is biased in favour of human action stimuli because these are more abundant than non-biological action stimuli in typical developmental environments.
Genetic instability in bladder cancer assessed by the comet assay.

BACKGROUND Latent genetic instability has been associated with an increased risk for several cancers. We used the comet assay (single-cell gel electrophoresis) to assess whether genetic instability, as reflected by susceptibility to DNA damage, was associated with the risk of bladder cancer in a case-control study. METHODS We used the comet assay to measure baseline and benzo[a]pyrene diol epoxide (BPDE)- and gamma-radiation-induced DNA damage in individual peripheral blood lymphocytes from 114 incident case patients with bladder cancer and 145 matched healthy control subjects. All subjects provided personal information, including smoking history. DNA damage was visualized with the comet assay and quantified by the Olive tail moment parameter, a relative measure. Multivariable analysis was used to assess relative risks for bladder cancer associated with DNA damage. All statistical tests were two-sided. RESULTS Baseline levels of DNA damage were statistically significantly higher in case patients (tail moment = 1.40) than in control subjects (tail moment = 1.21) (difference = 0.19, 95% confidence interval [CI] = 0.04 to 0.32; P =.015), as were gamma-radiation-induced (tail moment = 4.76 versus 4.22; difference = 0.54, 95% CI = 0.11 to 0.96; P =.013) and BPDE-induced (tail moment = 4.06 versus 3.45; difference = 0.61, 95% CI = 0.23 to 0.99; P =.002) DNA damage. When data were dichotomized at the median value for DNA damage in control subjects and adjusted for age, sex, ethnicity, and smoking status, an increased estimated relative risk of bladder cancer was statistically significantly associated with DNA damage at baseline (odds ratio [OR] = 1.84, 95% CI = 1.07 to 3.15) and after gamma-radiation (OR = 1.81, 95% CI = 1.04 to 3.14) but not after BPDE treatment (OR = 1.69, 95% CI = 0.98 to 2.93). CONCLUSION Latent genetic instability as measured by the comet assay is associated with an increased estimated relative risk of bladder cancer.
Moral disengagement in sport

Historically, theories of morality have focused predominantly on moral cognition at the expense of moral action. One theory that considers moral action as well as moral cognition is Bandura's (1991) Social Cognitive Theory of Moral Thought and Action. One aspect of this theory that has recently proved particularly popular with researchers investigating sport morality is that of moral disengagement. Moral disengagement is a collective term for eight psychosocial mechanisms that selectively inhibit moral standards from preventing reprehensible conduct by disengaging self-reproof when one engages in conduct that contravenes one's moral standards. In this review, research examining moral disengagement in the sport context is discussed. Research in this area can be grouped into two broad categories: (a) moral disengagement and behaviours that occur during sport participation; and (b) moral disengagement and doping in sport. The present review considers work addressing both categories. Within each category, the main findings of pertinent studies are discussed, and strengths and weaknesses of these studies are identified. The review concludes with directions for future research.
Evaluation of a commercial ligase chain reaction kit (Abbott LCx) for direct detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary specimens

Direct detection of Mycobacterium tuberculosis by means of a commercial ligase chain reaction DNA amplification method (LCx M. tuberculosis; Abbott Diagnostics Division, Abbott Park, Ill.) was investigated with 511 (including 147 extrarespiratory) specimens collected from 358 patients. LCx results were compared with standard microbiological data, and conflicting cases were resolved according to the final clinical diagnosis. M. tuberculosis was detected in 45 of 358 subjects by means of the LCx test. The test was negative for all 30 specimens with mycobacteria other than M. tuberculosis. The sensitivity, specificity, and positive and negative predictive values for the LCx test, compared with culture results, were 93.90, 92.31, 70.00, and 98.75%, respectively; these values rose in resolved cases to 95.53, 99.25, 97.27, and 98.75%, respectively. With respiratory specimens, for which the LCx system is licensed, the sensitivity reached 98.97%. In patients with a final clinical diagnosis of tuberculosis the sensitivity of the LCx system was 89.36% compared to 82.98% for cultures and 78.72% for microscopy. We conclude that the LCx test is user friendly, rapid, fairly sensitive, and highly specific. It can also be effectively used on extrapulmonary specimens provided possible false-negative results are taken into account. However, the use of LCx test appears to be less appropriate for the monitoring of antituberculosis therapy, as the majority of samples from treated tuberculosis patients gave consistently positive results, despite the sterilization of cultures.
The Relationship between Socio-Demographics and Stress Levels, Stressors, and Coping Mechanisms among Undergraduate Students at a University in Barbados

This study sought to learn about stress experienced by students enrolled in the Faculty of Social Sciences (FSS) at the University of the West Indies (UWI) in Barbados. This research was primarily undertaken to help UWI administrators/academic staff understand and address student stress. One hundred and six FSS students responded to:- (1) student perceptions on whether summer school courses were less stressful compared to semester courses, (2) the mean stress level associated with summer and semester courses, (3) FSS student stressors, and (4) coping mechanisms used by FSS students to handle stressors. The research revealed a statistically significant difference in the mean stress levels that students experienced between summer and semester courses. The key stressors identified were: (i) amount of work in each course, (ii) group projects being a nightmare, (iii) studying and working full-time, (iv) stress associated with work impacting studies, and (v) taking too many courses per semester. The primary coping strategies used by FSS students were: (i) taking some quiet time and then resuming studies, (ii) praying for renewed strength, (iii) sleeping more, (iv) eating more, and (v) engaging in a hobby. Statistically significant results were observed on several of the key stressors and coping mechanisms. The paper concludes by discussing implications for policy and practice which can aid UWI administration/academic staff to craft strategies that can assist in reducing the amount of stress experienced by students.
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE GROUP INVESTIGATION TERHADAP HASIL BELAJAR SISWA PADA MATERI POKOK SUHU DAN KALOR KELAS X SMA NEGERI I PERBAUNGAN

ABSTRAK Tujuan penelitian ini adalah untuk mengetahui pengaruh model pembelajaran kooperatif tipe Group Investigation terhadap hasil belajar siswa pada materi pokok suhu dan kalor di SMA Negeri I Perbaungan. Jenis penelitian adalah kuasi eksperimen. Populasi pada penelitian ini seluruh siswa kelas X SMA Negeri I Perbaungan sebanyak 6 kelas. Sampel dalam penelitian ini diambil dua kelas secara random sampling . Instrumen yang digunakan untuk mengetahui hasil belajar siswa pada materi suhu dan kalor dalam bentuk pilihan berganda yang berjumlah 20 soal dan lembar observasi. Hasil pengujian hipotesis diperoleh bahwa ada pengaruh yang signifikan antara penggunaan model pembelajaran kooperatif tipe Group Investigation terhadap hasil belajar siswa. Kata kunci: Model kooperatif tipe group investigation ABSTRACT The purpose of this study was to determine the effect of cooperative learning model Group Investigation on learning outcomes of students in the subject matter of temperature and heat in SMA I Perbaungan. This type of research is quasi-experimental. The population of this entire class X SMA Negeri I Perbaungan much as 6 classes. The sample in this study was taken as a random sampling of two classes. The instrument used to determine student learning outcomes in the material temperature and heat in the form of multiple-choice questions numbered 20 and the observation sheet. The results obtained by testing hypotheses is concluded that there is a significant relationship between the use of cooperative learning model Group Investigation on student learning outcomes. Keywords: Cooperative learning model group investigation .
Getting Wasted: Why College Students Drink Too Much and Party So Hard

Preface Acknowledgments 1 This Is the Shit Show! An Introduction to College Drinking 2 Getting Wasted: The Intoxication Process 3 Being Wasted: Fun, Adventure, and Transformation in the World of College Drinking 4 When Everything Falls Apart: Meeting the Challenges of the College Drinking Scene 5 The Morning After: Hangovers and Regrets 6 Using Drunk Support: Responding to the Persistence of Heavy Drinking Methodological Appendix Notes Bibliography Index About the Author
An investigation of intraday price discovery in cross-listed emerging market equities

ABSTRACT We investigate multi-market price discovery using two year intraday data for Egyptian and Argentinean depository receipts and their underlying stock. The contribution of the local versus international exchange to price discovery is assessed using the Gonzalo and Granger's permanent-transitory common factor model. Whereas price discovery in the local market for Egyptian equities accounted for 75,8% of the price discovery in the DR, the result was mixed for the Argentinean equities, with an average of only 41,67% of DR prices determined in the local market. We find that size of the company, liquidity and trading volume explain the contribution of each market.