Miracle-dz/UniFAR-FTUs huggingface dataset:
Dataflow Notebooks: Encoding and Tracking Dependencies of Cells

Computational notebooks have seen widespread adoption among scientists in many fields, and allow users to view interactive graphical results inline, to embed text and code together, to organize code into cells, and to selectively edit and re-execute cells. Because they allow quick and recordable analyses, they play an important role in documenting experiments. However, the reproducibility of notebooks can vary significantly due to the ordering of cells or changes in global state that affect the re-execution of those cells. In addition, in many popular notebook environments, cells are tagged with transient identifiers that change when a cell is re-executed so it is impossible to robustly reference other cells. We introduce dataflow notebooks as a method to allow users to explicitly encode dependencies between cells by adding a unique, persistent identifier to each cell and expanding incode references to results in other cells. In these notebooks, we can both pose and answer provenance queries about dependencies between cells. This permits new notebook operations like downstream updates which, given a change to one cell, allow users to update all cells that may be impacted by the change while leaving all other cells alone. At the same time, dataflow notebooks increase reproducibility and enable greater reuse by making dependencies clear.
The Role of Emotion in Global Warming Policy Support and Opposition

Prior research has found that affect and affective imagery strongly influence public support for global warming. This article extends this literature by exploring the separate influence of discrete emotions. Utilizing a nationally representative survey in the United States, this study found that discrete emotions were stronger predictors of global warming policy support than cultural worldviews, negative affect, image associations, or sociodemographic variables. In particular, worry, interest, and hope were strongly associated with increased policy support. The results contribute to experiential theories of risk information processing and suggest that discrete emotions play a significant role in public support for climate change policy. Implications for climate change communication are also discussed.
Heterogeneity and Learning in Labor Markets 1

This paper examines the role of agent heterogeneity and learning on wage dispersion and employment dynamics. In the rst half of the paper, I present an equilibrium matching model where heterogeneous workers and rms learn about match quality and bargain over wages. The model generalizes Jovanovic (1979) to the case of heterogeneous workers and rms. Equilibrium wage dispersion arises due to productivity di¤erences across workers, technological di¤erences across rms, and heterogeneity in beliefs about match quality. Under a simple CRS technology, the equilibrium wage is additively separable in workerand rm-speci c components, and in the posterior mean of beliefs about match quality. This parallels the person and rm e¤ectsempirical speci cation of Abowd et. al. (1999, AKM) and others. It consequently provides a theoretical context for the AKM model, and a formal economic interpretation of their empirical person and rm e¤ects. The model also yields an assortative matching result that predicts a negative correlation between estimated person and rm e¤ects, which is consistent with most empirical evidence. Finally, the model makes novel predictions about the relationship between the person and rm e¤ects and separation behavior, job duration, and rm size. In the second half of the paper, I test the models empirical predictions. I estimate xed and mixed e¤ects speci cations of the equilibrium wage function on the LEHD database. The mixed e¤ect speci cations generalize the earlier work of AKM and others. The learning component of the matching model implies a speci c structure for the error covariance. I exploit this structure to test whether earnings residuals are consistent with Bayesian learning, and to estimate structural parameters of the matching model. I nd considerable support for the matching model in these data.
Building Collective Efficacy: How Leaders Inspire Teachers to Achieve. Issue Brief.

Four years earlier the principal, Ed Carli, had organized his faculty into “cadres” with a leader-teacher of each cadre serving on the School Leadership Team (SLT). According to teachers and staff members, this organizational change improved communication and fostered shared decision making among teachers and school leaders. Despite improvements in student behavior and school climate, however, student performance continued to lag.
Complexity of 4-Manifolds

We define and study a notion of complexity for smooth, closed and orientable 4-manifolds. This notion, based on the theory of Turaev shadows, represents the 4-dimensional analogue of Matveev's complexity of 3-manifolds. We classify complexity-0 and complexity-1 4-manifolds and provide examples of manifolds of higher complexity.
Academic Resilience and Burnout Relationship of The Student of Qom University of Medical Sciences

Background and Aims: The main result of stress is academic burnout and academic resilience is flexibility and adaptability against stressors. It seems resilience is one of the most important influential factors on burnout. In this study the relation of academic resilience and burnout was investigated among the students of Qom University of Medical Sciences. Methods: In this cross-sectional study, 260 students were selected randomly in year 2016, from the list of all students of Qom University of Medical Sciences who were the statistical population of this study. Maslach academic burnout and Samuels academic resilience questionnaires were used to collect data. Data were analyzed by Spss software version 16. The significance level was 0.05 p. Results: In this study, the mean score of academic burnout was 34.32 ±14.87 and the mean score of academic resilience was 103.30 ±12.23. When variables were into multivariate regression model by ENTER, study in public health field had an increase in academic burnout by 9.73 (OR=9.73 95% CI=1.50-63.04). Optimism by 20% (OR=0.80 95% CI=0.71- 0.91) and communication skills by 5% (OR=0.95 95% CI=0.91- 0.99) had an effective role in academic burnout reduction. Conclusions: According to the results, resilient students had less vulnerability against academic burnout. So, the amplification of this variable among medical science students who are exposed to academic burnout can improve their academic performance.
An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation

Molecular mechanisms that control oligodendrocyte myelination during mammalian central nervous system (CNS) development are poorly understood. In this study, we identified Zfp488, an oligodendrocyte-specific zinc-finger transcription regulator, by screening for genes downregulated in the optic nerves of Olig1-null mice. The predicted primary structure of Zfp488 is evolutionarily conserved in vertebrates and invertebrates. In the developing CNS, Zfp488 is specifically expressed in oligodendrocytes but not their precursors. Its expression increases in parallel with that of major myelin genes Mbp and Plp1. Zfp488 is a nuclear protein that possesses transcriptional repression activity. In the developing chick neural tube, Zfp488 can promote oligodendrocyte precursor formation upon Notch activation. In addition, Zfp488 can interact and cooperate with the bHLH transcription factor Olig2 to promote precocious and ectopic oligodendrocyte differentiation. Furthermore, knockdown of Zfp488 via RNAi in an oligodendroglial cell line leads to the downregulation of myelin gene expression. Taken together, these data suggest that Zfp488 functions as an oligodendrocyte-specific transcription co-regulator important for oligodendrocyte maturation and that zinc-finger/bHLH cooperation can serve as a mechanism for oligodendroglial differentiation.
Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor.

CONTEXT Both GH releasing- and orexigenic properties of the gut-to-brain hormone ghrelin are mediated by the GH secretagogue receptor (GHSR). Recently in several patients, a missense mutation (p.A204E) resulting in a complete loss of GHSR constitutive activity has been implicated in short stature with dominant transmission. OBJECTIVE The objective of the study was to describe the phenotype associated with partial isolated GH deficiency of a young patient born to unrelated parents and identify the molecular basis of his disease. RESULTS The growth delay (-3.0 sd) was associated with recurrent episodes of abdominal pain, vomiting, ketosis, hypoglycemia, and a low body mass index. GHSR sequencing revealed that the patient was compound heterozygous for two new defects: 1) an early occurring transition predicting a premature stop codon (c.6G>A, p.W2X) inherited from his unaffected father, therefore strongly arguing against haploinsufficiency as a disease mechanism, and 2) a missense mutation (c.709A>T, p.R237W) inherited from his healthy mother, involving an evolutionary invariant residue from the third intracellular loop. In vitro experiments showed that the p.R237W mutation would result in a partial loss of constitutive activity of the receptor, whereas both its ability to respond to ghrelin and its cell surface expression are preserved. CONCLUSION These data, which describe the first case of recessive partial isolated GH deficiency due to GHSR mutations and emphasize the physiological importance of the GHSR in somatic growth, are discussed in light of the dominantly expressed p.A204E mutation.
Integrated Multi-Trophic Aquaculture ( IMTA ) on Growth of Abalones ( Haliotis squamata ) , Vannamei Shrimps ( Litopenaneus vannamei ) and Macroalgae ( Ulva lactuca )

10.21276/sajb.2018. 6.12. 7 Abstract: The study about modification of the integrated multi-trophic aquaculture (IMTA) was examined by adding components of scavenger organism namely Vannamei shrimp (Litopenaeus vannamei). The purpose of this study is to compare the production abalone per unit volume of water between the integrated system of abalone and macroalgae (Ulva lactuca) with the integrated system of shrimp, abalone and ulva. The completely randomized design (CRD) was using with three treatments, i.e. a) biomass ratio of shrimp: abalone: ulva = 4: 1: 40; b) biomass ratio of shrimp biomass: abalone: ulva = 2: 1: 40; and c) biomass ratio of shrimps: abalones: ulva = 0: 1: 40 (as a control), with three replication respectively. The results of the variance analysis (ANOVA) showed that the ulva cultivated in condition of high nitrogen compounds from residual metabolites of shrimp, grew faster than the ulva cultivated without shrimp. Enhancement of the shrimp biomass in the system will increase the growth of ulva. Aquaculture systems with larger shrimp biomass will produce ulva with a higher protein content than ulva harvested from nature. Abalone is consuming ulva in an integrated aquaculture system with larger shrimp biomass, grew faster than abalone no consuming ulva cultivated without shrimp.
Excellence in Technical Education: The Pathway of Quality Management

Education and especially technical education is recognized as a builder of both society and the nation. However, the precondition that it is fit in all respects must have been satisfied. The haziness in the definition of quality and hence ‘the fitness’ notwithstanding, requirements and expectations have been rightly raised to so called ‘excellence’ in education. The present work seeks to map the roadmap of improvement of (technical) education towards excellence, using quality, and/or quality management as the stimulus. By underpinning the triad model of Juran, the development of a case of quality utilizes the Joiner’s model to achieve total quality improvement. This may not have excluded the paradigm of TQM in (technical) education, and rather considers it as a label or as an ardent part of the same package within the conceptual initiative. The modulation of requirements of quality management makes a case that the total quality improvement process accents on the various core activities associated with the knowledge transfer to students through an environment which sustains the proliferation of ‘quality culture’ and plethoric use of quality, its management, through the optimal use of the quality management standard. The quality of their exploration as core technology, use of quality management (standard) as a tool and pursuance of quality as advised by Juran’s model and the institution’s quality culture shall determine what level of excellence will be achieved. Keywords: Quality assurance, TQM, quality management standard, Thareja's adaptation of Joiner’s model, 4-A model, PDCA Cite this Article Priyavrat Thareja. Excellence in Technical Education: The Pathway of Quality Management. Omni Science: A Multi-disciplinary Journal. 2017; 7(3): 7–22p.
Muscle-Derived Stem Cells for Bone and Cartilage Repair

Mathews Journal of Orthopedics Muscle-Derived Stem Cells for Bone and Cartilage Repair Xueqin Gao1,2, Johnny Huard1,2* 1Department of Orthopaedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas. 2Steadman Philippon Regenerative Institute, Center for Regenerative Sports Medicine. Corresponding Author: Johnny Huard, Department of Orthopaedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, Email: Johnny.Huard@uth.tmc. edu
photon view of an enzyme at work : Crotalus atrox venom PLA 2 interaction with single-lipid and mixed-lipid giant unilamellar vesicles

We describe the interaction of Crotalus atrox-secreted phospholipase A2 (sPLA2) with giant unilamellar vesicles (GUVs) composed of single and binary phospholipid mixtures visualized through two-photon excitation fluorescent microscopy. The GUV lipid compositions that we examined included 1-palmitoyl-2-oleoyl-phosphatidylcholine, 1,2-dipalmitoyl-snglycero-3-phosphocholine (DPPC), and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) (above their gel-liquid crystal transition temperatures) and two well characterized lipid mixtures, 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE):DMPC (7:3) and 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC)/1,2-diarachidoyl-sn-glycero-3-phosphocholine (DAPC) (1:1) equilibrated at their phase-coexistence temperature regime. The membrane fluorescence probes, 6-lauroyl-2(dimethylamino) napthalene, 6-propionyl-2-(dimethylamino) naphthalene, and rhodamine-phosphatidylethanolamine, were used to assess the state of the membrane and specifically mark the phospholipid domains. Independent of their lipid composition, all GUVs were reduced in size as sPLA2-dependent lipid hydrolysis proceeded. The binding of sPLA2 was monitored using a fluorescein-sPLA2 conjugate. The sPLA2 was observed to associate with the entire surface of the liquid phase in the single phospholipid GUVs. In the mixed-lipid GUV’s, at temperatures promoting domain coexistence, a preferential binding of the enzyme to the liquid regions was also found. The lipid phase of the GUV protein binding region was verified by the introduction of 6-propionyl-2-(dimethylamino) naphthalene, which partitions quickly into the lipid fluid phase. Preferential hydrolysis of the liquid domains supported the conclusions based on the binding studies. sPLA2 hydrolyzes the liquid domains in the binary lipid mixtures DLPC:DAPC and DMPC:DMPE, indicating that the solid-phase packing of DAPC and DMPE interferes with sPLA2 binding, irrespective of the phospholipid headgroup. These studies emphasize the importance of lateral packing of the lipids in C. atrox sPLA2 enzymatic hydrolysis of a membrane surface.
Dimensions of Market Demand Associated with Dance Schools

Dimensions of Market Demand Associated with Dance Schools Therefore the purpose of this study was to identify dimensions of market demand for dance schools. Dance is an activity requiring a strong relationship between the artist, marketer and audience. Marketing has generated sufficient commercial interest in the field, transforming dance into a thriving business. The growth of the dance industry has resulted in a highly competitive business environment. Effective management and marketing strategies (market segmentation, market promotion, program differentiation, and pricing strategy) may be formed for dance schools to ultimately satisfy consumer needs and also achieve business success. Cultural Learning, Personal Benefits, Program Offering, School Operation, Instruction Quality, and Economic Consideration would be positively predictive of the consumption level at dance schools. New technologies might also influence of purchase intent and must be consider by marketers.
Adoption of antitakeover legislation and R&D expenditure

We study the effect of the adoption of antitakeover legislation at the state level in the 1980s, on firm R&D expenditure. These laws limit hostile takeovers and hence effectively increase managerial discretion. Prior studies, using adoption of one or a few antitakeover measures report inconsistent evidence on the relation between antitakeover provisions and R&D expenditure. We contribute to this area of inquiry by examining the effect of state-level adoption of antitakeover laws during the 1980’s on firm-level R&D expenditure. Adopting a difference-in-difference methodology, we fail to find a significant change in R&D expenditure following the adoption of state antitakeover laws. Since state antitakeover laws are exogenous to managerial discretion, our results suggest that prior evidence documenting a significant association between antitakeover protection and R&D could be attributable to unobservable variables correlated with both antitakeover protection and R&D.
foxD 5 a , a Xenopus Winged Helix Gene , Maintains an Immature Neural Ectoderm via Transcriptional Repression That Is Dependent on the C-Terminal Domain

Xenopus foxD5a, the full-length fork head gene previously described as a PCR fragment (XFLIP), is first detectable at stage II of oogenesis. Low-abundance maternal transcripts are localized to the animal hemisphere of the cleavage embryo, and protein can be translocated to the nucleus prior to the onset of zygotic transcription. Zygotic expression is strongest in the presumptive neural ectoderm at gastrula and neural plate stages, but there is minor paraxial mesodermal expression during primary gastrulation that becomes significant in the tail bud during secondary gastrulation. Expression of foxD5a in animal cap explants induces elongation and expression of mesodermal, neural-inducing, and early neural-specifying genes, indicating a role in dorsal axis formation. Zygotic foxD5a expression is induced strongly by siamois, moderately by cerberus, weakly by Wnt8 and noggin, and not by chordin in animal cap explants. Expression of foxD5a in whole embryos has differential dorsal and ventral effects. Ventral mRNA injection induces partial secondary axes composed of expanded mesodermal and epidermal tissues, but does not induce ectopic neural tissues. Dorsal mRNA injection causes hypertrophy of the neural plate and expansion of early neural genes (sox3 and otx2), but this is not the result of increased proliferation or expanded neural-inducing mesoderm. The neural plate appears to be maintained in an immature state because otx2 expression is expanded and expression of en2, Krox20, proneural genes (Xnrgn1, neuroD) and a neural differentiation gene (n-tubulin) is repressed in foxD5a-expressing cells. These results indicate that foxD5a maintains an undifferentiated neural ectoderm after neural induction. Expression of foxD5a constructs fused with the engrailed repressor domain or with the VP16 activation domain demonstrates that FoxD5a acts as a transcriptional repressor in axis formation and neural plate expansion. Deletion constructs indicate that this activity requires the C-terminal domain of the protein.
Stability of Tempo Perception in Music Listening

This study was designed to determine whether listeners from different age groups and musical backgrounds (musicians and non-musicians) could set tempi in a consistent manner over an extended period. The variables of musical style, familiarity, and preference were also considered. Subjects heard the same six compositions on four separate occasions. The order of the presentation and the initial tempo of the examples were varied systematically in each session. Subjects were asked to listen to each composition and indicate whether the experimenter should set the tempo faster or slower until it sounded ‘right’ to them; they had to adjust an initially ‘wrong’ tempo to a personally preferred tempo . Results indicated that the initial tempo significantly dominated subjects' ‘correct’ tempo judgements: the slower initial tempo generally evoked slower tempo selections, and so on. However, a relatively small number of adults, mostly musicians, were remarkably consistent in their tempo judgements across all four trials. It appeared that these individuals possess an exceptional ability with respect to acute stability of large-scale timing in music. There was also evidence that the degree of consistency in correct tempo judgements gradually increased from preadolescence through adulthood. Few statistically significant differences in consistency of tempo judgements were found as a result of musical background. The findings strongly suggested that the style of musical examples influenced the degree of tempo consistency across trials. Moreover, there was statistically significant evidence that an increase of familiarity with, and preference for, the musical examples and the musical styles resulted in an increase of consistency of correct tempo judgements. The study concludes with recommendations for music education.
Is Growth Rate Implicit In Ipo Prices

This study examines (a) the cash flow growth rate implicit by offer prices of IPOs in an emerging market using a reverse engineering DCF model and (b) the bias of implicit growth relative to the realized growth rate. We find that the estimated growth in cash flows is slightly higher than realized growth rate, which indicates that the median IPO firm is overvalued by 81% at the offering. It is observed that the estimation errors increase as a result of higher underpricing and diversified ownership. In addition, post- IPO returns are smaller for issues whose implicit growth rates are biased upward. We also find that IPOs underperform in long-run while employing a buy-and-hold investment strategy.