Miracle-dz/UniFAR-FTUs huggingface dataset:
Evidential Morphology and Theory of Mind

The perennial fascination with the relationship between language and thought has generated much research across various disciplines. In recent years, commentators have called for closer examination of the connection between language acquisition and conceptual development (Bowerman & Levinson, 2001). Rather than assuming that language development always presupposes cognitive development, several researchers have started considering whether language learning could transform conceptual structure by making certain concepts available to the learner (e.g., de Villiers & Pyers, 1997; Gopnik & Choi, 1995; Bowerman, 1996). It has been suggested that linguistic categories might reasonably have cognitive consequences in domains far removed from perception, involving higher-level cognitive processing, where human cognitive representations appear to differ from those of other animals (Gentner & Boroditsky, 2001; Spelke & Tsivkin, 2001). The ability to attribute mental representations to oneself and to others, widely referred to as theory of mind, has been considered by many a promising arena for exploration of such effects (Carruthers, 1996; de Villiers & de Villiers, 1997). In this paper, we focus on one aspect of language and its potential effect on theory of mind development. Specifically, we examine the developmental relationship between children’s ability to reason about evidence for their own beliefs and the beliefs of others and the acquisition of evidential vocabulary. Human beings routinely make use of a variety of evidential sources in acquiring beliefs about the world (these sources include, e.g., direct perception, communication and inference). Humans also possess the ability to understand the connection between evidence and consequent effects on knowledge states. This ability is useful in tracking the pieces of evidence that led to the formation of a belief, assessing the reliability of a belief, and ultimately arriving at a set of
Using CSP to model and analyze Transmission Control Protocol vulnerabilities within the broadcast network

The spread of networks and their increasing complexity have complicated the task of security analysis. Accordingly, automatic verification approaches have received more attention recently. We have modeled a network, including a set of hosts (clients and servers), using the process algebra CSP (communicating sequential processes) in order to verify the Transmission Control Protocol (TCP) behavior against an active intruder. The model is verified using the FDR tool and, as a result, some attack scenarios which violate security are found. The scenarios show how an intruder can compromise the server trust to its clients. As the model is modular, extendable, and scalable, more complex attack scenarios (combinations of simple ones) can be detected using it.
Simulation of Seasonal Variation of Marine Boundary Layer Clouds over the Eastern Pacific with a Regional Climate Model

AbstractThe seasonal cycle of marine boundary layer (MBL) clouds over the eastern Pacific Ocean is studied with the International Pacific Research Center (IPRC) Regional Atmospheric Model (iRAM). The results show that the model is capable of simulating not only the overall seasonal cycle but also the spatial distribution, cloud regime transition, and vertical structure of MBL clouds over the eastern Pacific. Although the modeled MBL cloud layer is generally too high in altitude over the open ocean when compared with available satellite observations, the model simulated well the westward deepening and decoupling of the MBL, the rise in cloud base and cloud top of the low cloud decks off the Peru and California coasts, and the cloud regime transition from stratocumulus near the coast to trade cumulus farther to the west in both the southeast and northeast Pacific. In particular, the model reproduced major features of the seasonal variations in stratocumulus decks off the Peru and California coasts, includin.
Mastoparan, a G Protein Agonist Peptide, Differentially Modulates TLR4- and TLR2-Mediated Signaling in Human Endothelial Cells and Murine Macrophages1

Previous studies have implicated a role for heterotrimeric G protein-coupled signaling in B cells, monocytes, and macrophages stimulated with LPS and have shown that G proteins coimmunoprecipitate with membrane-bound CD14. In this study, we have extended these observations in human dermal microvessel endothelial cells (HMEC) that lack membrane-bound CD14 and in murine macrophages to define further the role of heterotrimeric G proteins in TLR signaling. Using the wasp venom-derived peptide, mastoparan, to disrupt G protein-coupled signaling, we identified a G protein-dependent signaling pathway in HMEC stimulated with TLR4 agonists that is necessary for the activation of p38 phosphorylation and kinase activity, NF-κB and IL-6 transactivation, and IL-6 secretion. In contrast, HMEC activation by TLR2 agonists, TNF-α, or IL-1β was insensitive to mastoparan. In the murine macrophage cell line, RAW 264.7, and in primary murine macrophages, G protein dysregulation by mastoparan resulted in significant inhibition of LPS-induced signaling leading to both MyD88-dependent and MyD88-independent gene expression, while TLR2-mediated gene expression was not significantly inhibited. In addition to inhibition of TLR4-mediated MAPK phosphorylation in macrophages, mastoparan blunted IL-1R-associated kinase-1 kinase activity induced by LPS, but not by TLR2 agonists, yet failed to affect phosphorylation of Akt by phosphoinositol-3-kinase induced by either TLR2- or TLR4-mediated signaling. These data confirm the importance of heterotrimeric G proteins in TLR4-mediated responses in cells that use either soluble or membrane-associated CD14 and reveal a level of TLR and signaling pathway specificity not previously appreciated.
Downlink Distributed Beamforming through Relay Networks

Beamforming and relaying are two methods of improving wireless system performance. Until now, these techniques have been considered separately. In this paper, a single source (basestation) with multiple antennas broadcasts to multiple single-antenna destinations through a network of single-antenna relays. A transmit precoder is first proposed to optimize the system for a set of fixed relay gains and phases (beamforming weights). Next, by straightforwardly generalizing results from the recent literature, these distributed relay beam-forming weights are optimized for this transmit precoder. The process is performed iteratively, and both problems are solved using semidefinite relaxation. For the special case of a single destination, we also provide a closed-form solution for relay optimization using a fixed linear precoder at the transmitter. Simulation results quantify the tradeoffs between the number of antennas at the basestation versus the number of relays, in terms of total relay network transmit power savings.
Positive and negative reasons for sickness presenteeism in Norway and Sweden: a cross-sectional survey

Objectives This article investigates various reasons for sickness presenteeism (SP), that is, going to work despite illness. The research questions asked is: What are the main reported reasons for SP in Norway and Sweden? Design Cross-sectional survey in Norway and Sweden. Use of binomial logistic regression analysis. Participants A random sample of people aged between 20 and 60 years was obtained from complete and updated databases of the Norwegian and Swedish populations. A postal questionnaire was sent to the selected individuals, with response rate 33% (n=2843). 2533 workers responded to questions about SP during the last 12 months. Primary and secondary outcome measures The article informs about the distribution of reasons for SP in Norway and Sweden, selected by the respondents from a closed list. The article also examines which factors influence the most often reported reasons for SP. Results 56% of the Norwegian and Swedish respondents experienced SP in the previous year. The most frequently reported reasons for SP include not burden colleagues (43%), enjoy work (37%) and feeling indispensable (35%). A lower proportion of Norwegians state that they cannot afford taking sick leave adjusted OR (aOR 0.16 (95% CI 0.10 to 0.22)), while a higher proportion of Norwegians refer to that they enjoy their work (aOR=1.64 (95% CI 1.28 to 2.09)). Women and young workers more often report that they do not want to burden their colleagues. Managers (aOR=2.19 (95% CI 1.67 to 2.86)), highly educated persons and the self-employed more often report that they are indispensable. Conclusions Positive and negative reasons for SP are reported, and there are significant differences between respondents from the two countries. The response rate is low and results must be interpreted with caution. Study design Cross-sectional study.
Computational Modeling of Microabscess Formation

Bacterial infections can be of two types: acute or chronic. The chronic bacterial infections are characterized by being a large bacterial infection and/or an infection where the bacteria grows rapidly. In these cases, the immune response is not capable of completely eliminating the infection which may lead to the formation of a pattern known as microabscess (or abscess). The microabscess is characterized by an area comprising fluids, bacteria, immune cells (mainly neutrophils), and many types of dead cells. This distinct pattern of formation can only be numerically reproduced and studied by models that capture the spatiotemporal dynamics of the human immune system (HIS). In this context, our work aims to develop and implement an initial computational model to study the process of microabscess formation during a bacterial infection.
Tropopause and hygropause variability over the equatorial Indian Ocean during February and March 1999

Measurements of temperature, water vapor, total water, ozone, and cloud properties were made above the western equatorial Indian Ocean in February and March 1999. The cold-point tropopause was at a mean pressure-altitude of 17 km, equivalent to a potential temperature of 380 K, and had a mean temperature of 190 K. Total water mixing ratios at the hygropause varied between 1.4 and 4.1 ppmv. The mean saturation water vapor mixing ratio at the cold point was 3.0 ppmv. This does not accurately represent the mean of the measured total water mixing ratios because the air was unsaturated at the cold point for about 40% of the measurements. As well as unsaturation at the cold point, saturation was observed above the cold point on almost 30% of the profiles. In such profiles the air was saturated with respect to water ice but was free of clouds (i.e., backscatter ratio <2) at potential temperatures more than 5 K above the tropopause and hygropause. Individual profiles show a great deal of variability in the potential temperatures of the cold point and hygropause. We attribute this to short timescale and space-scale perturbations superimposed on the seasonal cycle. There is neither a clear and consistent “setting” of the tropopause and hygropause to the same altitude by dehydration processes nor a clear and consistent separation of tropopause and hygropause by the Brewer-Dobson circulation. Similarly, neither the tropopause nor the hygropause provides a location where conditions consistently approach those implied by a simple “tropopause freeze drying” or “stratospheric fountain” hypothesis.
MAPGEN: Mixed-Initiative Planning and Scheduling for the Mars Exploration Rover Mission

The Mars Exploration Rover mission is one of NASA's most ambitious science missions to date. Launched in the summer of 2003, each rover carries instruments for conducting remote and in site observations to elucidate the planet's past climate, water activity, and habitability. Science is MER's primary driver, so making best use of the scientific instruments, within the available resources, is a crucial aspect of the mission. To address this criticality, the MER project team selected MAPGEN (mixed initiative activity plan generator) as an activity-planning tool. MAPGEN combines two existing systems, each with a strong heritage: the APGEN activity-planning tool from the Jet Propulsion Laboratory and the Europa planning and scheduling system from NASA Ames Research Center. We discuss the issues arising from combining these tools in this mission's context. MAPGEN is the first AI-based system to control a space platform on another planet's surface.
The role of dopamine in risk taking: a specific look at Parkinson’s disease and gambling

An influential model suggests that dopamine signals the difference between predicted and experienced reward. In this way, dopamine can act as a learning signal that can shape behaviors to maximize rewards and avoid punishments. Dopamine is also thought to invigorate reward seeking behavior. Loss of dopamine signaling is the major abnormality in Parkinson’s disease. Dopamine agonists have been implicated in the occurrence of impulse control disorders in Parkinson’s disease patients, the most common being pathological gambling, compulsive sexual behavior, and compulsive buying. Recently, a number of functional imaging studies investigating impulse control disorders in Parkinson’s disease have been published. Here we review this literature, and attempt to place it within a decision-making framework in which potential gains and losses are evaluated to arrive at optimum choices. We also provide a hypothetical but still incomplete model on the effect of dopamine agonist treatment on these value and risk assessments. Two of the main brain structures thought to be involved in computing aspects of reward and loss are the ventral striatum (VStr) and the insula, both dopamine projection sites. Both structures are consistently implicated in functional brain imaging studies of pathological gambling in Parkinson’s disease.
Host–Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity

The measles virus (MeV) is a contagious pathogenic RNA virus of the family Paramyxoviridae, genus Morbillivirus, that can cause serious symptoms and even fetal complications. Here, we summarize current molecular advances in MeV research, and emphasize the connection between host cells and MeV replication. Although measles has reemerged recently, the potential for its eradication is promising with significant progress in our understanding of the molecular mechanisms of its replication and host-pathogen interactions.
Effectiveness of Diabetes Self-Management Education on Quality of Life in Diabetic Elderly Females

Introduction: Diabetes is a chronic illness that requires continuing medical care and patient self-management education to reduce the risk of long-term and acute complications. The aim of the present study was to determine the effectiveness of diabetes self-management education on quality of life in elderly females with diabetic mellitus (type 2) in Shiraz, Iran, 2013. Method: The study was conducted from January to April 2014 at the Jahandidegan center, a day center affiliated to Shiraz welfare organization. The instrument used for the study was the Quality of life Questionnaire (WHO QOL-BREF) SF26. After an explanation of the aim of the study by the researcher, 90 participants with all the required criteria and G.H. Q score ≤ 23 were selected as the study sample for the intervention. Participants divided into experimental and control groups, and completed WHO QOL-BREF before the intervention, 2 and 3 months after the last session of education. Result: It is shown that 2 and 3 months after the intervention, QOL scores had a significant difference between the two groups. In other words, the training sessions improved the score of QOL in the intervention group (P < 0.001) versus control group (P = 0.5). Conclusion: The Behavioral Intervention Program significantly improved the quality of life outcomes of the diabetic elderly females. Thus, it is concluded that the diabetic individuals can be significantly improved following instruction by health care providers.
Detection and characterization of high affinity plasma membrane receptors for human interleukin 1

Interleukin 1 (IL-1) is a polypeptide hormone that acts as a central mediator of inflammation. Since IL-1 action is presumably mediated by specific cell surface receptor(s), we have characterized the binding of this hormone to cells. Purified human IL-1 was labeled to high specific activity with 125I, using Bolton-Hunter reagent. The labeled protein binds specifically to LBRM-33-1A5 (a murine T lymphoma line previously shown to produce IL-2 in response to phytohemagglutinin and IL-1) with an affinity of approximately 0.2-2 X 10(10)/M and, at saturation, to approximately 500 receptors per cell, on intact cells at 8 degrees C in the presence of sodium azide. The affinity of unmodified IL-1 for the murine plasma membrane receptor is 0.9-2 X 10(10)/M, as measured by the inhibition of 125I-IL-1 binding. The murine receptor specificity has been confirmed by demonstrating that, among a series of 12 polypeptide hormones, only IL-1 inhibits 125I-IL-1 binding to LBRM-33-1A5 cells. Treatment of surface-bound 125I-IL-1 with bivalent water-soluble crosslinkers identified a membrane polypeptide of Mr 79,500 to which IL- 1 is crosslinked. A variety of cell types have been surveyed for the capacity to bind 125I-IL-1 specifically. The presence of specific binding correlates with the capacity of the cells tested to respond to IL-1. Our results indicate that the biological effects of the polypeptide hormone IL-1 are mediated by high affinity plasma membrane receptors. The identification of these receptors should provide valuable insight into the apparently diverse biological activities of IL-1.
Travelers with cutaneous leishmaniasis cured without systemic therapy.

BACKGROUND Cutaneous leishmaniasis (CL) is a disfiguring but not life-threatening disease. Because antileishmanial drugs are potentially toxic, the World Health Organization (WHO) recommends simple wound care or local therapy as first-line treatment, followed or replaced by systemic therapy if local therapy fails or cannot be performed. METHODS To determine the feasibility and impact of the recommended approach, we analyzed the results of a centralized referral treatment program in 135 patients with parasitologically proven CL. RESULTS Infections involved 10 Leishmania species and were contracted in 29 different countries. Eighty-four of 135 patients (62%) were initially treated without systemic therapy. Of 109 patients with evaluable charts, 23 of 25 (92%) treated with simple wound care and 37 of 47 (79%) treated with local antileishmanial therapy were cured by days 42-60. In 37 patients with large or complex lesions, or preexisting morbidities, or who had not been cured with local therapy, the cure rate with systemic antileishmanial agents was 60%. Systemic adverse events were observed in 15 patients, all receiving systemic therapy. CONCLUSIONS In this population of CL patients displaying variable degrees of complexity and severity, almost two-thirds of patients could be initially managed without systemic therapy. Of these, 60 were cured before day 60. The WHO-recommended stepwise approach favoring initial local therapy therefore resulted in at least 44% of all patients being cured without exposure to the risk of systemic adverse events. Efforts are needed to further simplify local therapy of CL and to improve the management of patients with complex lesions and/or preexisting comorbidities.
Comparison of aortic diameter in normal subjects and patients with systemic hypertension.

BACKGROUND Standard aortic root dimensional measurement by the two dimensional echocardiography should be routinely performed in all patients. There is limited data on the normal reference on Thai population. OBJECTIVE Aims of this study were (1) to determine the normal reference of aortic root dimension in Thai population and (2) to determine the difference in the aortic root size in patients with hypertension comparing with normal population. MATERIAL AND METHOD We retrospectively reviewed 81 patients who had the transthoracic echocardiographic examinations in our echocardiographic lab and had the aortic root measurement data. The patients with ascending aortic aneurysm, aortic dissection, aortic stenosis and/or regurgitation more than mild in degree, Marfan's syndrome and annuloaortic ectasia were excluded. The echocardiographic data of were collected; the aortic root dimensions at four levels; aortic valve annulus, sinus of Valsava, sinotubular junction and tubular parts. Hypertension was indentified if the patient had the prior diagnosis of hypertension and on antihypertensive medications, or who had blood pressure more than 140/90 mmHg for two or more occasions. RESULTS Eighty-one patients were enrolled. Sixty patients (74.1%) were diagnosed hypertension. Mean age was 66.9 +/- 11.2 years in hypertensive patients and 49.1 +/- 16.4 years in normotensive patients. Normal reference values based on 95% upper normal limit of aortic valve annulus, sinus of Valsava, sinotubular junction and tubular part were 2.30 (2.21-2.38), 3.56 (3.35-3.77), 2.79 (2.61-2.97), and 3.36 (3.13-3.59), respectively. Patients with hypertension had significant larger sinus of Valsava and tubular part of aortic root than patients with normotension. CONCLUSION We reported a normal reference value for aortic root size in Thai population. The aortic root sizes are influenced by hypertensive status, age and gender.
Understanding staff nurse responses to change: utilization of a grief-change framework to facilitate innovation. 1994 [classical article].

This paper reviews the literature on the psychological effects of change and discusses the impact of an overarching organizational change on the staff nurses of a large oncology unit in the Midwest. Their reactions are compared with a grief-change framework synthesized from the literature. This framework was useful in explaining staff nurse behaviors and attitudes, and offered interventions specific to each stage of the change process useful to the CNS. Dissemination of this information is discussed, as well as implications for advanced nursing practice.
Social Preferences and Open Source Software Development

Open source software (OSS), and open innovation in general, has received increasing attention from both researchers and practitioners. Based on recent literature on social preference from behavior economics, we propose a finite-horizon dynamic model to study the interactions between OSS developers who are either purely self-interested or conditional cooperators. We find that selfinterested developers who are predicted to free ride under conventional analysis may contribute to a public good, and the existence of purely these developers may, under certain conditions, even benefit the provision of a public good. We further analyze how code architecture affects OSS development outcome and propose that a higher level of code modularity leads to more code contributions overall, due to the strategic behavior of self-interested developers. However, a right mix of the two types of developers plays a critical role for modular design to make an impact. The findings bear important theoretical as well as practical implications and provide guidelines for OSS development and the collective innovation in general.