Miracle-dz/UniFAR-FTUs huggingface dataset:
Small-Time Local Controllability and Stabilizability of Spacecraft Attitude Dynamics under CMG Actuation

The purpose of this paper is to examine whether the presence of singular configurations poses an obstruction to the small-time local controllability (STLC) and stabilizability of the attitude dynamics of a spacecraft actuated by single-gimbal control moment gyroscopes (CMGs). We identify a class of singular CMG configurations called critically singular configurations, at which the linearized dynamics fail to be controllable. Linear controllability, and hence STLC and stabilizability, hold at equilibria in which the CMG array is in a nonsingular or singular, but not critically singular, configuration. We give sufficient conditions and necessary conditions on critically singular configurations for STLC to hold. In particular, we show that STLC and stabilizability fail to hold at an equilibrium if the magnitude of the total spin angular momentum of the CMG array has a local maximum at the equilibrium.
Self-reported nonrestorative sleep in fibromyalgia – relationship to impairments of body functions, personal function factors, and quality of life

Purpose The purpose of this study was: 1) to determine variables that might characterize good or bad sleep; and 2) to describe the relationship between sleep, impairment of body functions, personal function factors, and quality of life based on quality of sleep in women with fibromyalgia (FM). Methods This cross-sectional descriptive study included 224 consecutive patients diagnosed at a specialist center. These patients were mailed a questionnaire concerning sleep, body functions, personal factors, and health-related quality of life. In total, 145 completed questionnaires were collected. Results Using sleep variables (sleep quality, waking up unrefreshed, and tiredness when getting up), we identified two subgroups – the good sleep subgroup and the bad sleep subgroup – of women with FM. These subgroups exhibited significantly different characteristics concerning pain intensity, psychological variables (depressed mood, anxiety, catastrophizing, and self-efficacy), impairments of body functions, and generic and health-related quality of life. The good sleep subgroup reported a significantly better situation, including higher employment/study rate. The bad sleep subgroup reported a greater use of sleep medication. Five variables determined inclusion into either a good sleep or a bad sleep subgroup: pain in the evening, self-efficacy, anxiety, and according to the Short Form health survey role emotional and physical functioning. Conclusion This study found that it was possible to identify two subgroups of women with FM based on quality of sleep variables. The two subgroups differed significantly with respect to pain, psychological factors, impairments of body functions, and perceived quality of life, where the subgroup with bad sleep had a worse situation.
The impact of diabetes mellitus on outcomes of endoscopic sinus surgery: a nested case‐control study

Given the immune impairment associated with diabetes mellitus (DM), its impact on chronic rhinosinusitis (CRS) is a potentially relevant concern; however, it has not been well‐studied. A single retrospective study reported worse postoperative quality of life outcomes in DM patients with CRS. Our study evaluated the effect of comorbid DM on outcomes of endoscopic sinus surgery (ESS) using a prospective study design.
Protease-Activated Receptor 1 Mediates Thrombin-Dependent, Cell-Mediated Renal Inflammation in Crescentic Glomerulonephritis

Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell–mediated renal injury was assessed in murine crescentic glomerulonephritis (GN). A pivotal role for thrombin in this model was demonstrated by the capacity of hirudin, a selective thrombin antagonist, to attenuate renal injury. Compared with control treatment, hirudin significantly reduced glomerular crescent formation, T cell and macrophage infiltration, fibrin deposition, and elevated serum creatinine, which are prominent features of GN. PAR-1–deficient (PAR-1−/−) mice, which have normal coagulation, also showed significant protection from crescentic GN compared with wild-type mice. The reductions in crescent formation, inflammatory cell infiltration, and serum creatinine were similar in PAR-1−/− and hirudin-treated mice, but hirudin afforded significantly greater protection from fibrin deposition. Treatment of wild-type mice with a selective PAR-1–activating peptide (TRAP) augmented histological and functional indices of GN, but TRAP treatment did not alter the severity of GN in PAR−/− mice. These results indicate that activation of PAR-1 by thrombin or TRAP amplifies crescentic GN. Thus, in addition to its procoagulant role, thrombin has proinflammatory, PAR-1–dependent effects that augment inflammatory renal injury.
Critical developments in the assessment of personality disorder.

BACKGROUND The assessment of personality disorder is currently inaccurate, largely unreliable, frequently wrong and in need of improvement. AIMS To describe the errors inherent in the current systems and to indicate recent ways of improving personality assessment. METHOD Historical review, description of recent developments, including temporal stability, and of studies using document-derived assessment. RESULTS Studies of interrater agreement and accuracy of diagnosis in complex patients with independently established personality status using document-derived assessment (PAS-DOC) with a four personality cluster classification, showed very good agreement between raters for the flamboyant cluster B group of personalities, generally good agreement for the anxious/dependent cluster C group and inhibited (obsessional) cluster D group, but only fair agreement for the withdrawn cluster A group. Overall diagnostic accuracy was 71%. CONCLUSIONS Personality function or diathesis, a fluctuating state, is a better description than personality disorder. The best form of assessment is one that uses longitudinal repeated measures using a four-dimensional system.
Early mobilization of patients hospitalized with community-acquired pneumonia.

STUDY OBJECTIVE To determine if early mobilization (EM) of hospitalized adults with community-acquired pneumonia (CAP) reduces hospital length of stay. DESIGN Group randomized trial. SETTING Three Midwestern hospitals. PARTICIPANTS Four hundred fifty-eight patients with CAP admitted to 17 general medical units between November 1997 and April 1998. INTERVENTION EM was defined as sitting out of bed or ambulating for at least 20 min during the first 24 h of hospitalization. Progressive mobilization occurred each subsequent day during hospitalization. MEASUREMENTS AND RESULTS Intervention (n = 227) and usual-care patients (n = 231) were similar in age, gender, disease severity, door-to-drug delivery time, and IV-to-po switchover time. Hospital length of stay for EM vs usual care was significantly less (mean, 5.8 vs 6.9 days; adjusted absolute difference, 1.1 days; 95% confidence interval, 0.0 to 2.2 days). There were no differences in adverse events or other secondary outcomes between treatment groups. CONCLUSIONS Like patients hospitalized with acute myocardial infarction and total knee replacements, EM of hospitalized patients with CAP reduces overall hospital length of stay and institutional resources without increasing the risk of adverse outcomes.
The Varying Effects of Uniaxial Compressive Stress on the Bainitic Transformation under Different Austenitization Temperatures

In this study, thermal simulation experiments under different austenitization temperatures and different stress states were conducted. High-temperature laser scanning confocal microscopy (LSCM), thermal dilatometry, and scanning electron microscope (SEM) were used to quantitatively investigate the effects of the uniaxial compressive stress on bainitic transformation at 330 °C following different austenitization temperatures. The transformation plasticity was also analyzed. It was found that the promotion degree of stress on bainitic transformation increases with the austenitization temperature due to larger prior austenite grain size as well as stronger promoting effect of mechanical driving force on selected variant growth at higher austenitization temperatures. The grain size and the yield strength of prior austenite are other important factors which influence the promotion degree of stress on bainitic transformation, besides the mechanical driving force provided by the stress. Moreover, the transformation plasticity increases with the austenitization temperature.
Switching loss characteristics of advanced DPWM methods using space vector based clamping sequences

This paper analyzes the inverter switching loss characteristics of space vector based discontinuous PWM (bus-clamping) sequences. The discontinuous PWM (DPWM) sequences considered in this paper are 012 and 721 sequences. Utilizing these two sequences and varying the zero state at a spatial angle γ where γ is between 0° and 60°an infinite number of advanced DPWM (ADPWM) methods can be generated. The aim of the paper is to analyze the inverter switching losses of ADPWM methods. Also it will be shown that steady state line current distortion during high modulation indices is reduced significantly compared with the conventional SVPWM (CSVPWM). So, compared with the CSVPWM the proposed ADPWM methods are advantageous both in reducing line current distortion as well as inverter switching losses.
Spatio-Temporal Analysis of the Accuracy of Tropical Multisatellite Precipitation Analysis 3B42 Precipitation Data in Mid-High Latitudes of China

Satellite-based precipitation data have contributed greatly to quantitatively forecasting precipitation, and provides a potential alternative source for precipitation data allowing researchers to better understand patterns of precipitation over ungauged basins. However, the absence of calibration satellite data creates considerable uncertainties for The Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) 3B42 product over high latitude areas beyond the TRMM satellites latitude band (38°NS). This study attempts to statistically assess TMPA V7 data over the region beyond 40°NS using data obtained from numerous weather stations in 1998–2012. Comparative analysis at three timescales (daily, monthly and annual scale) indicates that adoption of a monthly adjustment significantly improved correlation at a larger timescale increasing from 0.63 to 0.95; TMPA data always exhibits a slight overestimation that is most serious at a daily scale (the absolute bias is 103.54%). Moreover, the performance of TMPA data varies across all seasons. Generally, TMPA data performs best in summer, but worst in winter, which is likely to be associated with the effects of snow/ice-covered surfaces and shortcomings of precipitation retrieval algorithms. Temporal and spatial analysis of accuracy indices suggest that the performance of TMPA data has gradually improved and has benefited from upgrades; the data are more reliable in humid areas than in arid regions. Special attention should be paid to its application in arid areas and in winter with poor scores of accuracy indices. Also, it is clear that the calibration can significantly improve precipitation estimates, the overestimation by TMPA in TRMM-covered area is about a third as much as that in no-TRMM area for monthly and annual precipitation. The systematic evaluation of TMPA over mid-high latitudes provides a broader understanding of satellite-based precipitation estimates, and these data are important for the rational application of TMPA methods in climatic and hydrological research.
The X-ray emission of Lyman break galaxies

We present an analysis of the X-ray emission of a large sample of z∼3 Lyman break galaxies (LBGs), based on Chandra/ACIS observations of several LBG survey fields. A total of 24 LBGs are directly detected in the X-ray, approximately doubling the number of known detections. Thirteen of the LBGs have optical spectroscopic signatures of active galactic nucleus (AGN) activity, but almost all the other X-ray detections are also likely to host an accreting black hole based on their X-ray properties. The AGN exhibit a wide range in X-ray luminosity, from weak Seyferts to bright quasi-stellar objects (QSOs). An optical spectroscopy identified approximately one-third of the X-ray-detected sources as broad-line QSOs, one-third as narrow-line AGN (NLAGN) and one-third as normal star-forming LBGs. The fraction of X-ray-detected LBGs is 3 per cent, much lower than that which has been found for submillimetre-selected galaxies. Two galaxies have X-ray luminosities, spectra and fX/fopt values that are consistent with emission from star formation processes and are identified as candidate X-ray bright, pure starburst galaxies at z∼ 3. If powered solely by star formation, the sources would have star formation rates (SFRs) of 300–500 M⊙ yr−1. X-ray spectral analysis of the LBGs shows a mean photon index of Γ= 1.96 , similar to local AGN. There is evidence for absorption in at least 40 per cent of the objects. Significantly more absorption is evident in the NLAGN, which is consistent with AGN unification schemes. After correction for absorption, the narrow- and broad-line objects show the same average luminosity. X-ray-detected LBGs, spectroscopically classified as normal galaxies, however, are less luminous in both soft and hard X-ray bands, indicating that the host galaxy is outshining any optical AGN signature. Turning to the X-ray emission from LBGs without direct detections, stacking the X-ray flux in the two deepest Chandra fields under consideration [the Hubble Deep Field-North (HDF-N) and Groth–Westphal Strip (GWS)] produced significant detections in each, although the GWS result was marginal. The detection in the HDF-N gives an X-ray-derived SFR of 42.4 ± 7.8 M⊙ yr^−1 per LBG and, by comparing with the ultraviolet (UV) SFR, the implied UV extinction correction is 4.1 ± 0.8. The LBG sample was split into three bins based on UV magnitude to examine the correlation between UV and X-ray emission: for the limited statistics available, there was no evidence of any correlation.
Distinct subunit contributions to the activation of M-type potassium channels by PI(4,5)P2

Low-threshold voltage-gated M-type potassium channels (M channels) are tetraheteromers, commonly of two Kv7.2 and two Kv7.3 subunits. Though gated by voltage, the channels have an absolute requirement for binding of the membrane phospholipid phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) to open. We have investigated the quantitative relation between the concentration of a water-soluble PI(4,5)P2 analog, dioctanoyl-PI(4,5)P2 (DiC8-PI(4,5)P2), and channel open probability (Popen) by fast application of increasing concentrations of DiC8-PI(4,5)P2 to the inside face of membrane patches excised from Chinese hamster ovary cells expressing M channels as heteromeric Kv7.2/7.3 subunits. The rationale for the experiments is that this will mimic the effect of changes in membrane PI(4,5)P2 concentration. Single-channel conductances from channel current–voltage relations in cell-attached mode were 9.2 ± 0.1 pS with a 2.5-mM pipette [K+]. Plots of Popen against DiC8-PI(4,5)P2 concentration were best fitted using a two-component concentration–Popen relationship with high and low affinity, half-maximal effective concentration (EC50) values of 1.3 ± 0.14 and 75.5 ± 2.5 µM, respectively, and Hill slopes of 1.4 ± 0.06. In contrast, homomeric channels from cells expressing only Kv7.2 or Kv7.3 constructs yielded single-component curves with EC50 values of 76.2 ± 19.9 or 3.6 ± 1.0 µM, respectively. When wild-type (WT) Kv7.2 was coexpressed with a mutated Kv7.3 subunit with >100-fold reduced sensitivity to PI(4,5)P2, the high-affinity component of the activation curve was lost. Fitting the data for WT and mutant channels to an activation mechanism with independent PI(4,5)P2 binding to two Kv7.2 and two Kv7.3 subunits suggests that the two components of the M-channel activation curve correspond to the interaction of PI(4,5)P2 with the Kv7.3 and Kv7.2 subunits, respectively, that channels can open when only the two Kv7.3 subunits have bound DiC8-PI(4,5)P2, and that maximum channel opening requires binding to all four subunits.
Secondary processing effects and damage mechanisms in continuous-fiber ceramic composites

Continuous-fiber ceramic composites (CFCC) are a relatively new area of composite materials in research. Therefore, the feasibility of using abrasive waterjets (AWJ) as a secondary CFCC process was explored. Continuous fiber-reinforced advanced ceramic composite materials have been machined with the AWJ piercing and cutting process. The topography and morphology of the machined surfaces were evaluated with surface profilometry and scanning electron microscopy (SEM). The surface characteristics, in terms of roughness and the micro-mechanisms of material removal, were evaluated. The AWJ surface characteristics and associated damage to the CFCC were compared with that of a conventional diamond saw cut surface. The AWJ generated surface was found to be significantly different from that of the diamond saw machining surface and the micromechanical behavior of the material removal was strongly dependent on the fiber orientation.
Single-crystal CuIn1−xGaxSe2 films grown on lattice-matched Ge by low-temperature Pulsed Electron Deposition technique

We report on the epitaxial growth of Cu(In,Ga)Se2 (CIGS) thin films on n-type Ge substrates using the Pulsed Electron Deposition (PED) technique. Single-crystal films with smooth interface and no dislocations were obtained at a substrate temperature of 300°C with thickness above 1. 5μm. CIGS/Ge epilayers were characterized in terms of Transmission Electron Microscopy, X-Ray Diffraction and Photoluminescence. Preliminary results are very promising for a variety of potential applications as absorber layer in single and multi-junction thin-film solar cells.
Bilateral Reflex Fluctuations during Rhythmic Movement of Remote Limb Pairs

The modulation of spinal cord excitability during rhythmic limb movement reflects the neuronal coordination underlying actions of the arms and legs. Integration of network activity in the spinal cord can be assessed by reflex variability between the limbs, an approach so far very little studied. The present work addresses this question by eliciting Hoffmann (H-) reflexes in both limbs to assess if common drive onto bilateral pools of motoneurons influence spinal cord excitability simultaneously or with a delay between sides. A cross-covariance (CCV) sequence between reflexes in both arms or legs was evaluated under conditions providing common drive bilaterally through voluntary muscle contraction and/or rhythmic movement of the remote limbs. For H-reflexes in the flexor carpi radialis (FCR) muscle, either contraction of the FCR or leg cycling induced significant reduction in the amplitude of the peak at the zero lag in the CCV sequence, indicating independent variations in spinal excitability between both sides. In contrast, for H-reflexes in the soleus (SO) muscle, arm cycling revealed no reduction in the amplitude of the peak in the CCV sequence at the zero lag. This suggests a more independent control of the arms compared with the legs. These results provide new insights into the organization of human limb control in rhythmic activity and the behavior of bilateral reflex fluctuations under different motor tasks. From a functional standpoint, changes in the co-variability might reflect dynamic adjustments in reflex excitability that are subsumed under more global control features during locomotion.
Transcriptional Analysis of Tendril and Inflorescence Development in Grapevine (Vitis vinifera L.)

In grapevine (Vitis vinifera L.), the lateral meristem can give rise to either tendrils or inflorescences which are determined organs. To get insights into the processes of tendril and inflorescence development, we characterized the transcriptional variation taking place in both organs. The results of the global transcriptional analyses along tendril and inflorescence development suggested that these two homologous organs initially share a common transcriptional program related to cell proliferation and growth functions. In later developmental stages they showed organ specific gene expression programs related to the particular differentiation processes taking place in each organ. In this way, tendrils showed higher transcription of genes related to photosynthesis, hormone signaling and secondary metabolism than inflorescences, while inflorescences displayed higher transcriptional activity for genes encoding transcription factors, mainly those belonging to the MADS-box gene family. The expression profiles of selected transcription factors related with inflorescence and flower meristem identity and with flower organogenesis were generally conserved with respect to their homologs in model species. Regarding tendrils, it was interesting to find that genes related with reproductive development in other species were also recruited for grapevine tendril development. These results suggest a role for those genes in the regulation of basic cellular mechanisms common to both developmental processes.
Enhancing Native Forb Establishment and Persistence Using a Rich Seed Mixture

Establishing native forbs is crucial for invasive plant management and restoring a desirable plant community. Our objectives were to determine (1) if increasing forb seed density results in increased forb establishment; (2) if a species‐rich mixture of forbs has greater establishment and survivorship than a single species; and (3) if mixtures of forbs are more competitive with Spotted knapweed (Centaurea maculosa) than a forb monoculture. To test our first two objectives, we seeded monocultures of Purple coneflower (Echinacea angustifolia), Arrowleaf balsamroot (Balsamorhiza sagittata), Annual sunflower (Helianthus annuus), Dotted gayfeather (Liatris punctata), Western white yarrow (Achillea millefolium), Sticky geranium (Geranium viscosissimum), as well as a mixture of all forbs. Pots were seeded at 800 or 2,000 seeds/m2 and watered twice or thrice weekly. The highest seed density produced the highest plant density, which averaged 4.35 plants/pot. The density of the mixture was similar to the mean density seen for individual species, and it doubled in response to the highest seed density. To test our third objective, Spotted knapweed and Purple coneflower were arranged in an addition series matrix with a maximum total density of 4,000 seeds/pot. We found that the forb mixture was seven times more competitive with Spotted knapweed than Purple coneflower alone. Using a mixture of forbs rather than a single species enhances forb establishment in various and unpredictable environments because the mixture possesses a variety of traits that may match year–year and site–site conditions. Once established, the mixture may have a greater chance of persisting than a monoculture.