Miracle-dz/UniFAR-FTUs huggingface dataset:
Two Approaches to Maternal Depression Screening During Well Child Visits

ABSTRACT. The US Preventive Services Task Force (USPSTF) has recommended depression screening for adults. Screening mothers has special importance to pediatricians because of the impact of maternal depression on children. The two screening questions endorsed by the USPSTF may allow pediatricians to screen mothers during routine well child care. This study explores the feasibility and yield of interview- and paper-based pediatric screening for maternal depression during well child visits. A structured interview script was developed to inquire about maternal depression. It included the two-question screen and required less than 1 minute to administer. An alternative paper-based screen asked the two questions after a brief written introduction providing the rationale. Four community pediatric practices in New Hampshire and Maine were trained in both screening approaches and developed plans on how to respond to positive screens (either question positive). The 11 providers at these sites tested the two approaches on two different series of mothers at well child visits. The pediatricians also reported barriers to the screening inquiries, maternal responses, and subsequent clinician actions and referrals. The pediatricians screened 250 mothers via the scripted interview. In a second trial, 223 women had paper-based depression screening. Yields from the paper-based screen were 22.9% versus 5.7% for the interview-based screener. Pediatricians also took on the new role of discussion of possible depression in about two thirds of cases. Subsequently, 7.6% of all women with paper-based screening were referred to mental health versus 1.6% with the interview-based screening. With the interview, mothers of children younger than 1 year of age were less likely to screen positive than those with older children (1.9% vs. 8.5%, p = .04). With the paper-based screener, no age differences in positive screen rates occurred. While both approaches to screening were feasible in primary care, the yield from the two different approaches differed substantially. This finding deserves exploration in future studies. With either of these screening approaches, pediatricians could enhance their detection of mothers at risk of depression. The outcomes of pediatrician screening and the best approach to follow-up care still need to be determined.
Effect of Lithium Disilicate Ceramic Thickness on the Color of Discromic Substate

The aim of this study was to evaluate the influence of the thickness of lithium disilicate ceramics (medium opacity) on the color perception of pressed full-ceramic restorations, in various situations of discromic substrate. The color parameters of ceramic disks (10 mm diameter, thickness 0.3, 0.6, 0.9, 1.2, 1.5mm), (n=5), of IPS e.max® Press MO 0 (Ivoclar Vivadent) were evaluated upon samples of light cured composite material that simulate the shade of prepared teeth (IPS Natural Die Material Kit, Ivoclar Vivadent) (disks 10mm diameter, 5mm thickness). Saturated sucrose solution was interposed between the ceramic disks and the composite disks. The color parameters CIE L*, a*, b* were recorded by using a spectrophotometer (VITA Easyshade® Advance, VITA Bad Säckingen, Germany). The color difference E was calculated. Statistical analysis of the data revealed that the increase in thickness of the ceramic layer will lead to an increased masking of the discolored background by the ceramic layer.
A Comparative Study of Selected Physical and Biochemical Traits of Wild-Type and Transgenic Sorghum to Reveal Differences Relevant to Grain Quality

Transgenic sorghum featuring RNAi suppression of certain kafirins was developed recently, to address the problem of poor protein digestibility in the grain. However, it was not firmly established if other important quality parameters were adversely affected by this genetic intervention. In the present study several quality parameters were investigated by surveying several important physical and biochemical grain traits. Important differences in grain weight, density and endosperm texture were found that serve to differentiate the transgenic grains from their wild-type counterpart. In addition, ultrastructural analysis of the protein bodies revealed a changed morphology that is indicative of the effect of suppressed kafirins. Importantly, lysine was found to be significantly increased in one of the transgenic lines in comparison to wild-type; while no significant changes in anti-nutritional factors could be detected. The results have been insightful for demonstrating some of the corollary changes in transgenic sorghum grain, that emerge from imposed kafirin suppression.
Molecules Clarify a Cnidarian Life Cycle – The “Hydrozoan” Microhydrula limopsicola Is an Early Life Stage of the Staurozoan Haliclystus antarcticus

Background Life cycles of medusozoan cnidarians vary widely, and have been difficult to document, especially in the most recently proposed class Staurozoa. However, molecular data can be a useful tool to elucidate medusozoan life cycles by tying together different life history stages. Methodology/Principal Findings Genetic data from fast-evolving molecular markers (mitochondrial 16S, nuclear ITS1, and nuclear ITS2) show that animals that were presumed to be a hydrozoan, Microhydrula limopsicola (Limnomedusae, Microhydrulidae), are actually an early stage of the life cycle of the staurozoan Haliclystus antarcticus (Stauromedusae, Lucernariidae). Conclusions/Significance Similarity between the haplotypes of three markers of Microhydrula limopsicola and Haliclystus antarcticus settles the identity of these taxa, expanding our understanding of the staurozoan life cycle, which was thought to be more straightforward and simple. A synthetic discussion of prior observations makes sense of the morphological, histological and behavioral similarities/congruence between Microhydrula and Haliclystus. The consequences are likely to be replicated in other medusozoan groups. For instance we hypothesize that other species of Microhydrulidae are likely to represent life stages of other species of Staurozoa.
Cooperative output regulation of multi-agent systems

In this paper, we will describe the cooperative output regulation problem for multi-agent systems. The formulation of this problem generalizes the leader-following consensus problem in the sense that the problem simultaneously addresses asymptotic tracking and disturbance rejection, accounts for model uncertainty, and accommodates a general leader system. Like the classical output regulation problem, this problem can be handled by the feedforward control approach and the internal model approach. These two approaches can also be used to handle other cooperative control problems of multi-agent systems such as formation, rendezvous, and flocking. We will also briefly overview some recent results on this problem, and point out some possible new avenues of this research problem.
Möbius syndrome

© 2016 Journal of Neurosciences in Rural Practice | Published by Wolters Kluwer Medknow A 6‐year‐old female child presented to our hospital with intellectual disability, global developmental delay, seizures, bilateral congenital squint, and features of facial weakness. On examination, the patient had lower motor facial nerve palsy and was unable to move both sides of her face and forehead. Her skin was devoid of wrinkles. She was unable to close her mouth, raise her eyebrows, or speak clearly. The patient also suffered from bilateral abducens nerve palsy with congenital internal strabismus and associated partial ophthalmoplegia. Lateral gaze paralysis was also present, indicating medial longitudinal fascicular involvement. The child also had syndactyly and small uneven‐sized limbs. Magnetic resonance imaging (MRI) of the brain [Figures 1 and 2] revealed depression of the floor of the fourth ventricle, hypoplasia of the medulla, pons, and bilateral middle cerebellar peduncles with absent facial colliculi. The cisternal and canalicular segments of bilateral facial nerves were absent. These features are suggestive of Möbius syndrome.
Which firms benefit more from the “own-firm” and spillover effects of inward foreign direct investment?

An interesting issue in the research of host country effects of foreign direct investment (FDI) that is highly relevant to the government policy of the FDI in the host country would be the following. Are the benefits of inward FDI in the form of “own-firm” effects of FDI in foreign subsidiaries and positive spillover effects to the rest of firms captured to larger extent by some certain types of enterprises in the host economy? Are there particular characteristics of a firm (often called absorptive capacity, e.g. by Cohen, Levinthal 1989) that determine whether it can benefit from positive spillovers? In this paper we try to assess these issues based on enterprise level panel data from Estonia. We find that for the total factor productivity and labour productivity effects of FDI at the subsidiary level, the characteristics like export or domestic market orientation of the affiliate may matter. We do not find that the selected indicators like exporting, R&D activity, technology intensity of the sector matter for benefiting from horizontal spillovers of FDI in Estonia.
Vitamin D intake and lung cancer risk in the Women's Health Initiative.

BACKGROUND Prior research suggests that vitamin D protects against lung cancer only among certain subgroups. OBJECTIVES We investigated whether vitamin D intake was associated with lung cancer and explored whether vitamin A intake modified the association. DESIGN Prospective cohort data from 128,779 postmenopausal women, including 1771 incident lung cancers in the Women's Health Initiative (Clinical Trials and Observational Study) 1993-2010, were analyzed. Twelve percent of women received active intervention (1 g Ca + 400 IU vitamin D3/d) in the Calcium/Vitamin D Trial. Baseline total intake included both dietary intake (from food-frequency questionnaires) and supplement intake (from bottle labels). HRs were estimated by Cox proportional hazard models. RESULTS No significant association was observed overall. Among never smokers, a total vitamin D intake ≥400 IU/d was significantly associated with lower risks of lung cancer (HR: 0.37; 95% CI: 0.18, 0.77 for ≥800 compared with <100 IU/d; P-trend = 0.01). No significant effect modification of total vitamin A intake on the association between total vitamin D intake and lung cancer was found. However, the Calcium/Vitamin D Trial active intervention was significantly associated with a lower lung cancer risk only among women with a vitamin A intake <1000 μg/d retinol activity equivalents (HR: 0.69; 95% CI: 0.50, 0.96; P-interaction = 0.09). CONCLUSIONS Vitamin D intake was associated with a lower lung cancer risk in never-smoking, postmenopausal women. Lower vitamin A intake may be important for a beneficial association of 1 g Ca + 400 IU vitamin D3 supplementation with lung cancer. This trial was registered at clinicaltrials.gov as NCT00000611.
Service Selection Based on Fuzzy TOPSIS Method

With rapid development of service-oriented architecture and cloud computing, web services have been widely adopted for developing various kinds of applications. A set of non-functional requirements such as QoS has become important criteria for service selection. The nature of QoS based service selection can be treated as a multiple criteria group decision making (MCDM) problem. This article presents an evaluation method based on the technique for Order Preference by Similarity to an Ideal Solution (TOPSIS) to help service consumers and providers to analyze available web services with fuzzy opinions. A set of pre-defined linguistic variables parameterized by triangular fuzzy numbers, are used by the group to evaluate the weights of various criteria and the ratings of each alternative web service. As a result, the available alternative web services can be ordered according to group preference. Finally, a numerical example is provided to demonstrate the computational efficiency of the proposed fuzzy TOPSIS method.
Nutritional and anthropometric profile of adolescent volleyball athletes

Women's participation in volleyball began in 1928. In 1944, the first Brazilian volleyball championship happened. Flexibility, strength, power, agility and aerobic fitness are all necessary to be a master in this sport. Women's participation in sport activity has increased. However, there are only a few studies in Brazil about nutrition assessment, especially amongst female volleyball players. Therefore, the aim of this study is to assess the dietetic and anthropometric profiles of 25 female adolescent volleyball players of Rio de Janeiro (15-20 years old). Anthropometric assessment was obtained by body mass, stature, skinfold and circumference measurements. Prospective 3-day records, that include two weekdays and one weekend day were analyzed by a Brazilian nutrition software (CIS/EPM, 1993) to obtain the nutrient intake and the results were compared to the American recommendations. The results of anthropometric evaluation showed that athletes had body mass of 64.35 ± 6.12 kg, stature of 1.74 ± 0.06 m and fat mass of 20.51 ± 2.43%. Diets consisted of high energy and protein intake, and low carbohydrate intake. The consumption of calcium, folate and vitamin E was below the recommendations. Since these athletes are going through a period of intense growth and development associated with rigorous training, it becomes, therefore, necessary for them to receive individualized nutritional orientation to improve their performance and quality of life.
Asthma is associated with acute chest syndrome, but not with an increased rate of hospitalization for pain among children in France with sickle cell anemia: a retrospective cohort study

Asthma and sickle cell disease are two common chronic diseases that may exist as co-morbid conditions. Our group has recently demonstrated that asthma, the most common chronic disease among children, is a distinct co-morbid condition among children with sickle cell anemia (SCA)[1][1] and has a
Average and randomized communication complexity

The communication complexity of a two-variable function f(x,y) is the number of information bits two communicators need to exchange to compute f when, initially, each knows only one of the variables. There are several communication-complexity measures corresponding to whether (1) the worst case or average number of bits is considered, (2) computation errors are allowed and (3) randomization is allowed. Tight bounds are provided for the typical behavior of all bounded-error communication-complexity measures of Boolean functions. In the present work, the authors formally define the deterministic model. They describe randomized protocols and compare them to deterministic ones. They both survey previous work and describe original results. >
Coupled grain boundary and surface diffusion in a polycrystalline thin film constrained by substrate

Abstract It has recently been shown [1] that constrained grain boundary diffusion in a stressed polycrystalline thin film causes exponential relaxation of grain boundary traction, leading to formation of crack-like diffusion wedges via mass transport between the grain boundaries and the free surface of the film. It was assumed in [1] that surface diffusion is very fast compared to grain boundary diffusion and surface tension is very large so that the film surface remains perfectly flat during the diffusion process. In this paper, we try to relax some of these assumptions by extending the analysis of [1] to coupled grain boundary and surface diffusion. We use Mullins’ equation to describe surface evolution, with mass conservation and continuity of chemical potential strictly enforced at the junctions between grain boundaries and the free surface. The surface diffusion is treated as a matter source or sink for the grain boundary diffusion and, assuming the surface slope is small, we neglect the effect of surface slope on the normal stress and chemical potential along the grain boundary. No sliding or diffusion is allowed at the film/substrate interface. We develop singular integral equation techniques to numerically solve the integro-differential governing equations for the strongly coupled deformation and diffusion problem. The characteristic time for constrained grain boundary diffusion is found to scale with the cubic power of the film thickness and depends on an effective diffusivity combining surface diffusivity and grain boundary diffusivity. The results indicate that constrained grain boundary diffusion leads to the formation of crack-like grain boundary diffusion wedges.
Transcriptomic Analysis of Soil-Grown Arabidopsis thaliana Roots and Shoots in Response to a Drought Stress

Drought stress has a negative impact on crop yield. Thus, understanding the molecular mechanisms responsible for plant drought stress tolerance is essential for improving this beneficial trait in crops. In the current study, a transcriptional analysis was conducted of gene regulatory networks in roots of soil-grown Arabidopsis plants in response to a drought stress treatment. A microarray analysis of drought-stressed roots and shoots was performed at 0, 1, 3, 5, 7, and 9 days. Results indicated that the expression of many drought stress-responsive genes and abscisic acid biosynthesis-related genes was differentially regulated in roots and shoots from days 3 to 9. The expression of cellular and metabolic process-related genes was up-regulated at an earlier time-point in roots than in shoots. In this regard, the expression of genes involved in oxidative signaling, chromatin structure, and cell wall modification also increased significantly in roots compared to shoots. Moreover, the increased expression of genes involved in the transport of amino acids and other solutes; including malate, iron, and sulfur, was observed in roots during the early time points following the initiation of the drought stress. These data suggest that plants may utilize these signaling channels and metabolic adjustments as adaptive responses in the early stages of a drought stress. Collectively, the results of the present study increases our understanding of the differences pertaining to the molecular mechanisms occurring in roots vs. shoots in response to a drought stress. Furthermore, these findings also aid in the selection of novel genes and promoters that can be used to potentially produce crop plants with increased drought tolerance.
Lactococcus lactis As a Versatile Vehicle for Tolerogenic Immunotherapy

Genetically modified Lactococcus lactis bacteria have been engineered as a tool to deliver bioactive proteins to mucosal tissues as a means to exert both local and systemic effects. They have an excellent safety profile, the result of years of human consumption in the food industry, as well as a lack of toxicity and immunogenicity. Also, containment strategies have been developed to promote further application as clinical protein-based therapeutics. Here, we review technological advancements made to enhanced the potential of L. lactis as live biofactories and discuss some examples of tolerogenic immunotherapies mediated by mucosal drug delivery via L. lactis. Additionally, we highlight their use to induce mucosal tolerance by targeted autoantigen delivery to the intestine as an approach to reverse autoimmune type 1 diabetes.
CANOPY GAP CHARACTERISTICS AND DROUGHT INFLUENCES IN OAK FORESTS OF THE COWEETA BASIN ’

Abstrac t . Canopy gaps in southern Appalachian mixed-Quercus forests were characterized to assess the impact of the 1985-l 988 record drought on patterns of tree mortality in relation to topographic variables and changes in overstory composition. Using permanent transects, we sampled 68 canopy gaps within the Coweeta Basin. Among l-5 yr old gaps, the most common gap type was the I-yr-old single-tree snag, accounting for 49% of all gaps sampled; 65% of all gaps occurred within 2 yr of the drought peak. Gap area ranged from 40 to 850 m’, averaged 239 m’, with a median of 152 m’. Analysis of 1988 color infrared (IR) aerial imagery yielded a gap formation rate of 0.8 gaps’ha’ . yr ’ in mixedQuercus stands affecting 2.00/o of the area in this forest type in 1988. The most frequent gap-forming species were Quercus coccinea, Q. ruhra, and Q. velutina, respectively. Evidence suggests that moisture stress brought on by severe drought increases the susceptibility of Quercus species to the shoe-string fungus Armillaria mellea, which may result in significant shifts in canopy composition in these forests. Kc>. v words: canopy gaps; Coweta; di.rtwbance; drought; mi.recl-oak,forests; predisposal; southern Appalachians; trm mortality
Customizing Internal Activity Behaviour for Flexible Process Enforcement

Workflow technology has met with success in a variety of industries, although several limitations have emerged. One such drawback is the inflexibility of specification languages, including a lack of support for inter-task dependencies. Expressiveness of the specification language is believed to be a determining factor of workflows applicability and its industrial value as solution for process support.This paper attempts to address this limited language expressiveness by suggesting an alternative approach to modelling that more accurately captures behavioural information about tasks and enables greater precision when modelling inter-task dependencies.Current workflow technology associates one generic, predefined finite state machine with each activity in a process, and inter-task dependencies of the type 'completion of one activity triggers scheduling of the next activity' are also enforced.The potential improvement relaxes these constraints to enable the specification of user-defined finite state machines to represent each activity and support the modelling of inter-task constraints at the activity state level. In this paper, we present an introduction to this modelling extension and demonstrate the applicability of existing workflow verification algorithms to these more descriptive process models.
fMRI neurofeedback facilitates anxiety regulation in females with spider phobia

Background: Spider phobics show an exaggerated fear response when encountering spiders. This fear response is aggravated by negative and irrational beliefs about the feared object. Cognitive reappraisal can target these beliefs, and therefore has a fear regulating effect. The presented study investigated if neurofeedback derived from functional magnetic resonance imaging (fMRI) would facilitate anxiety regulation by cognitive reappraisal, using spider phobia as a model of anxiety disorders. Feedback was provided based on activation in left dorsolateral prefrontal cortex and right insula, as indicators of engagement and regulation success, respectively. Methods: Eighteen female spider phobics participated in a randomized, controlled, single-blinded study. All participants completed a training session in the MRI scanner. Participants assigned to the neurofeedback condition were instructed to shape their regulatory strategy based on the provided feedback. Participants assigned to the control condition were asked to adapt their strategy intuitively. Results: Neurofeedback participants exhibited lower anxiety levels than the control group at the end of the training. In addition, only neurofeedback participants achieved down-regulation of insula activation levels by cognitive reappraisal. Group differences became more pronounced over time, supporting learning as a mechanism behind this effect. Importantly, within the neurofeedback group, achieved changes in insula activation levels during training predicted long-term anxiety reduction. Conclusions: The conducted study provides first evidence that fMRI neurofeedback has a facilitating effect on anxiety regulation in spider phobia.