Miracle-dz/UniFAR-FTUs huggingface dataset:
Shared atypical default mode and salience network functional connectivity between autism and schizophrenia

Schizophrenia and autism spectrum disorder (ASD) are two prevalent neurodevelopmental disorders sharing some similar genetic basis and clinical features. The extent to which they share common neural substrates remains unclear. Resting‐state fMRI data were collected from 35 drug‐naïve adolescent participants with first‐episode schizophrenia (15.6 ± 1.8 years old) and 31 healthy controls (15.4 ± 1.6 years old). Data from 22 participants with ASD (13.1 ± 3.1 years old) and 21 healthy controls (12.9 ± 2.9 years old) were downloaded from the Autism Brain Imaging Data Exchange. Resting‐state functional networks were constructed using predefined regions of interest. Multivariate pattern analysis combined with multi‐task regression feature selection methods were conducted in two datasets separately. Classification between individuals with disorders and controls was achieved with high accuracy (schizophrenia dataset: accuracy = 83%; ASD dataset: accuracy = 80%). Shared atypical brain connections contributing to classification were mostly present in the default mode network (DMN) and salience network (SN). These functional connections were further related to severity of social deficits in ASD (p = 0.002). Distinct atypical connections were also more related to the DMN and SN, but showed different atypical connectivity patterns between the two disorders. These results suggest some common neural mechanisms contributing to schizophrenia and ASD, and may aid in understanding the pathology of these two neurodevelopmental disorders. Autism Res 2017, 10: 1776–1786. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.
Proteomic Analysis of Matrix of Dental Biofilm Formed under Dietary Carbohydrate Exposure

To evaluate whether protein changes in extracellular matrix of dental biofilm are a unique property of sucrose, this in situ study was conducted using as active control glucose and fructose, the sucrose monosaccharide constituents. Proteins were analyzed by two-dimensional electrophoresis followed by LC-MS/MS after trypsin digestion. Absence or lower abundance of calcium-binding proteins and higher abundance of prolactin-induced proteins were found in biofilm formed in the presence of sucrose or its monosaccharide constituents compared with water, the negative control group. The data suggest that besides sucrose, other dietary carbohydrates may also provoke a change in the protein profile of extracellular matrix of dental biofilm formed.
Couples Sharing Recovery from a Husband's Addiction to Pornography: A Qualitative Study

COUPLES SHARING RECOVERY FROM A HUSBAND’S SEXUAL ADDICTION TO PORNOGRAPHY: A QUALITATIVE STUDY Spencer T. Zitzman Department of Marriage and Family Therapy Masters of Science This study evaluated the therapy process for married couples recovering from addictive use of pornography. The author’s proposal was that in conjoint couple therapy, clinicians are able to help organize the relationship to sponsor recovery while helping both members of the relationship heal individually. The prevalence and effects of pornography are discussed through a review of the current literature. Six couples were interviewed following the termination of their treatment in marital therapy to gain a holistic view of the process of recovery and gain groundwork for future development of a concise model of treatment. Results demonstrated that an increase in understanding of each other’s position in the sexual addiction and recovery process (i.e., emotional, cognitive and behavioral) increases a) marital trust and faith in the future, b) softening towards each other, c) the ability to discern key points of intervention in helping the other spouse during recovery, and d) client-perceived marital enhancement. These preliminary findings suggest that couples perceive that conjoint marital therapy is a useful component in treating addiction to pornography.
PKS 2123-463: a confirmed γ -ray blazar at high redshift

The flat spectrum radio quasar (FSRQ) PKS 2123−463 was associated in the first Fermi-Large Area Telescope (LAT) source catalogue with the γ-ray source 1FGL J2126.1−4603, but when considering the full first two years of Fermi observations, no γ-ray source at a position consistent with this FSRQ was detected, and thus PKS 2123−463 was not reported in the second Fermi-LAT source catalogue. On 2011 December 14 a γ-ray source positionally consistent with PKS 2123−463 was detected in flaring activity by Fermi-LAT. This activity triggered radio-to-X-ray observations by the Swift, Gamma-ray Optical/Near-Infrared Detector (GROND), Australia Telescope Compact Array (ATCA), Ceduna and Seven Dishes Karoo Array Telescope (KAT-7) observatories. Results of the localization of the γ-ray source over 41 months of Fermi-LAT operation are reported here in conjunction with the results of the analysis of radio, optical, ultraviolet (UV) and X-ray data collected soon after the γ-ray flare. The strict spatial association with the lower energy counterpart together with a simultaneous increase of the activity in optical, UV, X-ray and γ-ray bands led to a firm identification of the γ-ray source with PKS 2123−463. A new photometric redshift has been estimated as z = 1.46 ± 0.05 using GROND and Swift Ultraviolet/Optical Telescope (UVOT) observations, in rough agreement with the disputed spectroscopic redshift of z = 1.67. We fit the broad-band spectral energy distribution with a synchrotron/external Compton model. We find that a thermal disc component is necessary to explain the optical/UV emission detected by Swift/UVOT. This disc has a luminosity of ∼1.8 × 1046 erg s−1, and a fit to the disc emission assuming a Schwarzschild (i.e. non-rotating) black hole gives a mass of ∼2 × 109 M⊙. This is the first black hole mass estimate for this source.
Efficacy of the methoxyflurane as bridging analgesia during epidural placement in laboring parturient

Background: Establishing an epidural in an agitated laboring woman can be challenging. The ideal pain control technique in such a situation should be effective, fast acting, and short lived. We assessed the efficacy of inhalational methoxyflurane (Penthrox™) analgesia as bridging analgesia for epidural placement. Materials and Methods: Sixty-four laboring women who requested epidural analgesia with pain score of ≥7 enrolled in an observational study, 56 of which completed the study. The parturients were instructed to use the device prior to the onset of uterine contraction pain and to stop at the peak of uterine contraction, repeatedly until epidural has been successfully placed. After each (methoxyflurane inhalation-uterine contraction) cycle, pain, Richmond Agitation Sedation Scale (RASS), nausea and vomiting were evaluated. Maternal and fetal hemodynamics and parturient satisfaction were recorded. Results: The mean baseline pain score was 8.2 ± 1.5 which was reduced to 6.2 ± 2.0 after the first inhalation with a mean difference of 2.0 ± 1.1 (95% confidence interval 1.7-2.3, P < 0.0001), and continued to decrease significantly over the study period (P < 0.0001). The RASS scores continuously improved after each cycle (P < 0.0001). Only 1 parturient from the cohort became lightly sedated (RASS = −1). Two parturients vomited, and no significant changes in maternal hemodynamics or fetal heart rate changes were identified during treatment. 67% of the parturients reported very good or excellent satisfaction with treatment. Conclusion: Penthrox™ provides rapid, robust, and satisfactory therapy to control pain and restlessness during epidural placement in laboring parturient.
Towards the development of a cognitive-behavioural model of relationship dissolution distress

There is a large body of research demonstrating that the dissolution of a romantic relationship remains a prospective risk factor for the development of a variety of emotional and clinical problems. Nevertheless, research into the factors that contribute to the variance in distress experienced between individuals has been relatively overlooked in terms of systematic enquiry. A literature review was therefore carried out with a view of understanding further those variables most salient in accounting for individual difference reactions following relationship dissolution. 21 studies examining correlates of relationship dissolution distress were reviewed. Results suggested that a range of variables significantly influence the distress experienced following loss including attachment orientation, personality characteristics, cognitive-behavioural variables and relationship-specific factors. However, it has not yet been examined how such variables may systematically be related and an empirically validated model of relationship dissolution distress has not yet been be proposed within the clinical literature. Twenty-seven participants reporting difficulties adjusting following the dissolution of a relationship were therefore interviewed about their experiences and completed self-report measures pertaining to attachment style and personality characteristics. The aim of the research was to assess for commonality of themes and contribute to the development of a theoretical model of relationship attachment, similar to those available in the research for other emotional disorders. Research objectives were met. Consistency of themes across individuals led to the proposal of a cognitive-behavioural model of relationship dissolution distress. The model is both theoretically and clinically derived and incorporates a number of factors hypothesised to exacerbate and maintain distress over time. The findings have useful clinical implications and point to promising targets of cognitive and behavioural intervention. A critical appraisal contextualises the researcher’s motives for wishing to investigate this particular area and provides a reflective account of the antecedents of this research, borne out of ‘bottom up’ clinical practice.
Social Policy, Employment and Family Change in Comparative Perspective

Contents: Foreword1. Introduction Jonathan Bradshaw and Aksel Hatland2. Family Change Naomi Finch3. The Parental Employment Context Emese Mayhew4. State Recognition of New Family Forms? Cecilie Wehner and Peter Abrahamson5. Parental Rights and Obligations Aksel Hatland and Emese Mayhew6. Family Benefit Packages Jonathan Bradshaw and Emese Mayhew7. Childcare and Parental Leave Naomi Finch8. Fertility Rates in Europe: The Influence of Policy, Economy and Culture Arieke Rijken9. First Births: A Comparative Study of the Patterns of Transition to Parenthood in Europe Katja Forssen and Veli-Matti Ritakallio10. Men and (Their) Families: Comparative Perspectives on Men's Roles and Attitudes Towards Family Formation Trudie Knijn, Ilona Ostner and Christoph Schmitt11. Education, Employment and Family Formation: Differing Patterns Ulla Bjornberg, Stefan A"lafsson and Guony Bjork Eydal12. Working Their Way Out of Poverty? Lone Mothers in Policies and Labour Markets Anne Skevik13. Family Poverty in the European Union Veli-Matti Ritakallio and Jonathan Bradshaw14. Gender Equity and Time Use: How Do Mothers and Fathers Spend Their Time? Naomi Finch15. ConclusionsUlla Bjornberg and Jonathan BradshawIndex
Size Signals Success: Evidence from Real Estate Private Equity

Anecdotal evidence suggests that clout and connections matter more in private equity fundraising than do actual performance. In this article, a unique real estate private equity dataset with buy-side and sell-side information is created by the authors to construct and analyze stacked interaction networks for each vintage year. Calculating and regressing centrality measures for industry embeddedness, the authors find that fund managers can benefit from their established connections to plan sponsors while fundraising. By adding fund size into the equation, they demonstrate that the total capital under management and the size of previous funds have a significant and positive effect on fundraising speed.
Book Review Essay : Catherine Cassel and Gillian Symon (eds.): Qualitative Methods in Organizational Research: A Practical Guide 1994, London: Sage. 253 pages

of the standards and agendas inherent in quantitative methods. The book under review pursues a different aim in that it tries to go beyond the traditional discussions of ’techniques’ in qualitative research, even though some of those techniques are also included. The editors and many of the authors give considerable attention to the fact that talk about quantitative and qualitative methods invariably implies talk about very different epistemological assumptions, a topic that only gets a side glance, if at all, in most methods books addressing organizational research. More importantly, this book not only attempts to look at qualitative methods with respect to different epistemologies. It also attempts to make a start at focusing implicitly and explicitly on different research agendas, i.e. different aims and fundamental assumptions in doing research, research which takes qualitative methods and their fundamental assumptions seriously. The aim of this text, therefore, seems to be to help in redirecting the meaning of qualitative research away from being understood only as an appendage to research agendas that characterize quantitative research. This is a powerful idea! It can be understood to argue that with respect
Modeling the Spread of Influence for Independent Cascade Diffusion Process in Social Networks

Modeling the spread of influence in online social networks is important for predicting the influence of individualsand better understanding many scenarios in social networks, such as the influence maximization problem. The previous work on modeling the spread of influence makes the assumption that the statuses of nodes in a network are independent of each other,which is apparently not correct for social networks. The goal of this work is to derive an accurate mathematical model to characterize the spread of influence for the independent cascade diffusion process in online social networks. Specifically, we apply the susceptible-infected-recovered epidemic model from epidemiology to characterize the independent cascade diffusion processand derive a general mathematical framework. To approximate the complex spatial dependence among nodes in a network, we propose a Markov model to predict the spread of influence. Through the extensive simulation study over several generated topologies and a real coauthorship network,we show that our designed Markov model has much better performance than the existing independent model in predicting the influence of individuals in online social networks.
The Psychology of Self-Esteem: A Revolutionary Approach to Self-Understanding that Launched a New Era in Modern Psychology

Preface to the 32nd Anniversary Edition Introduction Part One: The Foundations 1. Psychology as a Science 2. Man: A Living Being 3. Man: A Rational Being 4. Man: A Being of Volitional Consciousness 5. Emotions 6. Mental Health Part Two: The Psychology of Self-Esteem 7. The Nature and Source of Self-Esteem 8. Pseudo-Self-Esteem 9. Pathological Anxiety: A Crisis of Self-Esteem 10. Social Metaphysics 11. Self-Esteem and Romantic Love 12. Psychotherapy Epilogue: Working with Self-Esteem in Psychotherapy Notes Index.
The Bank of Standardized Stimuli (BOSS), a New Set of 480 Normative Photos of Objects to Be Used as Visual Stimuli in Cognitive Research

There are currently stimuli with published norms available to study several psychological aspects of language and visual cognitions. Norms represent valuable information that can be used as experimental variables or systematically controlled to limit their potential influence on another experimental manipulation. The present work proposes 480 photo stimuli that have been normalized for name, category, familiarity, visual complexity, object agreement, viewpoint agreement, and manipulability. Stimuli are also available in grayscale, blurred, scrambled, and line-drawn version. This set of objects, the Bank Of Standardized Stimuli (BOSS), was created specifically to meet the needs of scientists in cognition, vision and psycholinguistics who work with photo stimuli.
Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans

Recently, the prevalence of Fasciola hepatica in some areas has increased considerably and the availability of a vaccine to protect livestock from infection would represent a major advance in tools available for controlling this disease. To date, most vaccine-target discovery research on this parasite has concentrated on proteomic and transcriptomic approaches whereas little work has been carried out on glycosylation. As the F. hepatica tegument (Teg) may contain glycans potentially relevant to vaccine development and the Newly Excysted Juvenile (NEJ) is the first lifecycle stage in contact with the definitive host, our work has focused on assessing the glycosylation of the NEJTeg and identifying the NEJTeg glycoprotein repertoire. After in vitro excystation, NEJ were fixed and NEJTeg was extracted. Matrix-assisted laser desorption ionisation-time of flight-mass spectrometry (MALDI-TOF-MS) analysis of released N-glycans revealed that oligomannose and core-fucosylated truncated N-glycans were the most dominant glycan types. By lectin binding studies these glycans were identified mainly on the NEJ surface, together with the oral and ventral suckers. NEJTeg glycoproteins were affinity purified after targeted biotinylation of the glycans and identified using liquid chromatography and tandem mass spectrometry (LC-MS/MS). From the total set of proteins previously identified in NEJTeg, eighteen were also detected in the glycosylated fraction, including the F. hepatica Cathepsin B3 (FhCB3) and two of the Cathepsin L3 (FhCL3) proteins, among others. To confirm glycosylation of cathepsins, analysis at the glycopeptide level by LC-ESI-ion-trap-MS/MS with collision-induced dissociation (CID) and electron-transfer dissociation (ETD) was carried out. We established that cathepsin B1 (FhCB1) on position N80, and FhCL3 (BN1106_s10139B000014, scaffold10139) on position N153, carry unusual paucimannosidic Man2GlcNAc2 glycans. To our knowledge, this is the first description of F. hepatica NEJ glycosylation and the first report of N-glycosylation of F. hepatica cathepsins. The significance of these findings for immunological studies and vaccine development is discussed.
ABSTRACT Title of dissertation: A MULTILEVEL INVESTIGATION OF LEADER EMPOWERING BEHAVIORS: INTEGRATING THE JOB DEMANDS-CONTROL MODEL AND TRANSACTIVE MEMORY SYSTEM THEORY

Title of dissertation: A MULTILEVEL INVESTIGATION OF LEADER EMPOWERING BEHAVIORS: INTEGRATING THE JOB DEMANDS-CONTROL MODEL AND TRANSACTIVE MEMORY SYSTEM THEORY Yuntao Dong Doctor of Philosophy, 2013 Dissertation directed by: Dr. Kathryn M. Bartol Robert H. Smith Professor of Management and Organization Empowering leader behaviors have been generally suggested to motivate employees and facilitate their goal achievement, but they can also be challenging and demanding. Yet questions regarding why employees may feel challenged and even concerned when empowered and how leaders can reduce such unfavorable reactions have been largely ignored in the literature. To examine the multifaceted impacts of empowering leadership and, at the same time, consider how the empowerment climate created by the leader at the team level may help facilitate the individual-level leadership processes, this research integrates the job demandscontrol (JD-C) model and the transactive memory system (TMS) literature to advance and test a model of the impacts of leader empowering behaviors on individuals and teams, as well as interrelationships of the multilevel dynamics. Applying the JD-C model, I propose that empowering leadership can provide team members with learning opportunities but also generate perceptions of role overload, which then influence, in opposite directions, their engagement and performance. Further incorporating the TMS literature, I propose that by creating an empowerment climate, leaders can help foster the development of TMS within the team. TMS will, in turn, benefit team performance as well as produce a positive cross-level influence on individual team members. Using survey data from 74 research and development teams in 14 high-technology companies in China, hierarchical linear modeling and hierarchical regression analyses provided overall support for the model. Theoretical and practical implications are also discussed in this dissertation. A MULTILEVEL INVESTIGATION OF LEADER EMPOWERING BEHAVIORS: INTEGRATING THE JOB DEMANDS-CONTROL MODEL AND TRANSACTIVE MEMORY SYSTEM THEORY
The Logic of Intuitive Decision Making: A Research-Based Approach for Top Management

Weston Agor has with scholarly thoroughness taken intuition out of the classroom and out of the business closet. He shows how it can be used as a powerful business tool. Roy Rowan, Author of The Intuitive Manager The Message of The Logic of Intuitive Decision Making is: 'Actively seek input and advice from all sources you possibly can before making a key decision,' according to the author. What follows is an outline of how to use intuition--an often-overlooked source--to make key management and personal decisions, a discussion of how to develop your intuition, and case studies of intuitive decision-making. Association Management
Sudden cardiac arrest during sports.

This editorial refers to ‘Major regional disparities in outcomes after sudden cardiac arrest during sports’, by E. Marijon et al. doi:10.1093/eurheartj/eht282 and ‘Exercise-related out-of-hospital cardiac arrest in the general population: incidence and prognosis’, by J. Berdowski et al. doi:10.1093/eurheartj/eht401 Exercise can trigger an acute cardiac event which may precipitate sudden cardiac arrest (SCA). 1 On the other hand, exercise is important for physical fitness and prevention of cardiovascular disease,1 and the medical community should therefore inform the general public of the health benefits of sports and exercise.2 At the same time, the public are exposed to alarmist mass media coverage of athletes or ordinary people collapsing during different sport activities, raising uncertainties, questions, and debate within communities. The worst possible consequence would be that the public abstain from physical exercise. It is therefore of utmost importance to document the current reality of sports-related SCA. In two studies from France and The Netherlands, the incidence and prognosis of exercise-related out-of-hospital cardiac arrest (OHCA) have now been reported.3,4 Different epidemiological characteristics and factors associated with improved survival were explored, analysed, and investigated. In a 5-year community-based French registry assessing the incidence and outcome of SCA during sports in subjects of 10–75 years old, Marijon and co-workers recorded 820 SCAs, with a mean age of 46 years and a 20:1 predominance of male victims. Half of the SCAs occurred in typical sports facilities. Their major finding was huge regional disparities related to survival. The overall survival at hospital discharge was 16%, varying from 3% in the worst regions up to 44% in the best regions. As in OHCA in general, bystander cardiopulmonary resuscitation (CPR) was a main contributor to the survival differences, …
Maintaining multiple motion model hypotheses over many views to recover matching and structure

In order to recover structure from images it is desirable to use many views to obtain the best possible estimates. However, whilst recovering projective structure and motion from such extended sequences problems arise that are not apparent from a general view-point/structure approach. Foremost amongst these are (a) maintaining image correspondences consistently through many images, and (b) identifying images, within the sequence, for which structure cannot be reliably recovery. Within this paper the use of multiple motion model hypotheses is explored as an aid to solve both of these problems.