Miracle-dz/UniFAR-FTUs huggingface dataset:
Care in Collaboration: Preventing Secondary Victimisation Through a Holistic Approach 
to Pre-Court Sexual Violence Interventions

Although men's sexual violence is well known as a problem of epidemic proportions and a cause of significant harm, effective prevention strategies have yet to be developed and the effectiveness of services for victims cannot be guaranteed. Most victims of sexual violence choose not to report, but those who do may still incur exacerbation of rape's destructive effects by those who are meant to help. Interested to know how responsiveness could be improved, I began this study by examining the literature on services for victims in order to identify the ingredients of good practice. Integrated specialist services which include support and advocacy with legal/forensic services emerged as the ideal. Finding that such systems had been positively evaluated in their real-life applications, New Zealand' s responsiveness was analysed with reference to this multi-agency model. I was particularly interested to know what supported the development of such a model and what the impediments might be to its development in New Zealand. Since literature indicated that government input was vital to implementation of specialist holistic practice, examination of New Zealand government and its Police responsiveness became the primary goal of data-gathering. With Police Districts as the units of study, data was collected from site visits and semi-structured interviews with police in each District. This data was triangulated through prolonged participant observation and interviews with medical/forensic and support/advocacy personnel. I found that specialist holistic services were regularly available for child sexual abuse victims. In contrast, for adult sexual violence victims these were rare and service gaps were rife. This was due to governance bodies failing to coordinate nationally or locally in funding and supporting service development. Explanations for this failure are found in feminist critiques of the patriarchal systems which privilege men' s needs over women's safety. I argue that with women's movement into public life and with the political will, nationally-based reform of services is now possible. Given its small size, New Zealand is particularly well-placed to achieve this reform if current governance structures are employed in constructing a national framework for nationwide development of specialist multi-agency practice.
Local Kelvin-Helmholtz instability and synchrotron modulation in Pulsar Wind Nebulae

We present here a series of numerical simulations of the development of Kelvin-Helmholtz instability in a relativistically hot plasma. The physical parameters in the unperturbed state are chosen to be representative of local conditions encountered in Pulsar Wind Nebulae (PWNe), with a main magnetic field perpendicular to a mildly relativistic shear layers. By using a numerical code for Relativistic MHD, we investigate the effect of an additional magnetic field component aligned with the shear velocity, and we follow the evolution of the instability to the saturation and turbulent regimes. Based on the resulting flow structure, we then compute synchrotron maps in order to evaluate the signature of Kelvin-Helmholtz instability on the emission and we investigate how the time scale and the amplitude of the synchrotron modulations depend on shear velocity and magnetic field. Finally we compare our results to the observed variable features in the Crab Nebula. We show that the Kelvin-Helmholtz instability cannot account for the wisps variability, but it might be responsible for the time dependent filamentary structure observed in the main torus.
Credit in Rural India: A Case Study

This paper presents a case study of credit transactions in Palanpur, a north Indian village. Drawing on detailed informtion from all borrowers and lenders in the village, we examine a number of issues related to the functioning of rural credit markets. These include the segmentation of the credit market, the achievements and failure of public lending institutions, the role of interest-free lending, the lending strategies of village moneylenders, social inequalities in access to credit, and the politics of rural credit, among others. An attempt is also made to relate these findings to those of other studies of credit in rural India.
A constructive algorithm for training cooperative neural network ensembles

Presents a constructive algorithm for training cooperative neural-network ensembles (CNNEs). CNNE combines ensemble architecture design with cooperative training for individual neural networks (NNs) in ensembles. Unlike most previous studies on training ensembles, CNNE puts emphasis on both accuracy and diversity among individual NNs in an ensemble. In order to maintain accuracy among individual NNs, the number of hidden nodes in individual NNs are also determined by a constructive approach. Incremental training based on negative correlation is used in CNNE to train individual NNs for different numbers of training epochs. The use of negative correlation learning and different training epochs for training individual NNs reflect CNNEs emphasis on diversity among individual NNs in an ensemble. CNNE has been tested extensively on a number of benchmark problems in machine learning and neural networks, including Australian credit card assessment, breast cancer, diabetes, glass, heart disease, letter recognition, soybean, and Mackey-Glass time series prediction problems. The experimental results show that CNNE can produce NN ensembles with good generalization ability.
Aberrant expression of angiopoietins-1 and -2 and vascular endothelial growth factor-A in peri-implantation endometrium after gonadotrophin stimulation.

BACKGROUND Ovarian stimulation affects normal endometrial development. The expression of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A) and the vascular state in the peri-implantation endometrium in women with natural and gonadotrophin-stimulated cycles were compared. METHODS The expression of these angiogenesis-associated molecules in endometrial biopsies, collected on Day 7 after human chorionic gonadotrophin injection or luteinizing hormone surge in stimulated or natural cycles respectively, or at mid-luteal phase of women undergoing diagnositic laparoscopy, were analysed. RESULTS Women with gonadotrophin-stimulation had lower Ang-1, but higher Ang-2, mRNA and protein expression (P < 0.05), and increased concentrations of von Willebrand factor (vWF) and blood vessel density than those with natural cycles (P < 0.05). Although stimulated cycles had higher VEGF-A mRNA expression (P = 0.023), VEGF-A protein expression was similar between the groups. Lower Ang-1/Ang-2 but higher Ang-2/VEGF-A mRNA ratios (P = 0.025) were found after gonadotrophin-stimulation. The ratios were negatively (P < 0.001) and positively correlated (P < 0.001) with estradiol levels, respectively. Cyclical changes in Ang-1 and Ang-2, but not in VEGF-A expression were noted. CONCLUSIONS The decreased Ang-1 concentration and Ang-1/Ang-2 ratio and the increased Ang-2 concentration, with the increased vWF concentration and blood vessel density, in stimulated cycles suggests advanced endometrial angiogenesis after gonadotrophin-stimulation.
A Candidate Gene Analysis of Methylphenidate Response in Attention-Deficit / Hyperactivity Disorder

Laboratorio per la Salute Materno Infantile ADHD ATTENTION DEFICIT HYPERACTIVITY DISORDER Per la ricerca degli articoli pubblicati nella letteratura scientifica nel mese in esame sono state consultate le banche dati Medline, Embase, PsycINFO e PsycArticle utilizzando le seguenti parole chiave (o i loro sinonimi): 'Attention deficit disorder', 'Attention deficit hyperactivity disorder', 'Infant', 'Child', 'Adolescent', 'Human'. Sono qui riportate le referenze considerate rilevanti e pertinenti. • realizzare un network stabile dei Centri di Riferimento per l'ADHD in Lombardia.
The Rise and Fall of Small Worlds: Exploring the Dynamics of Social Structure

This paper explores the interplay between social structure and economic action by examining some of the evolutionary dynamics of an emergent network that coalesces into a small-world system. The study highlights the small-world system’s evolutionary dynamics at both the macro level of the network and the micro level of an individual actor. This dual analytical lens helps establish that, in competitive and information-intensive settings, a small-world system could be a highly dynamic structure that follows an inverted U-shaped evolutionary pattern, wherein an increase in the smallworldliness of the system is followed by its later decline due to three factors: (1) the recursive relationship between the evolving social structure and individual actors’ formation of bridging ties, which eventually homogenizes the information space and decreases actors’ propensity to form bridging ties, creating a globally separated network; (2) self-containment of the small-world network, or increasing homogenization of the social system, which makes the small world less accepting of and less attractive to new actors, thereby limiting formation of bridging ties to outside clusters; and (3) fragmentation of the small-world network, or the small-world system’s inability to retain current clusters. The study uses data on interorganizational tie formation in the global computer industry in the period from 1996 to 2005 to test the hypothesized relationships. may to the same cluster thus each other little informational differently, they offer a lower incentive for establishing a bridging connection than firms come from a different cluster, linking to which provides an entrée into an entirely new community of firms with potentially rich and novel knowledge and resource pools. We therefore expected between-cluster bridging ties, rather than simply ties to disconnected contacts, to play a very significant role in accessing diverse knowledge and resources. To ensure that we are not sidestepping an important empirical factor in small-world dynamics, throughout the paper we also discuss results based on a within-cluster metric of brokerage, such as network constraint
Connecting, Trusting, and Participating: The Direct and Interactive Effects of Social Associations

In recent years, research has come to recognize that nonpolitical associations have unintended but important consequences for citizens’ participation in public affairs. Scholars theorize that these associational activities—embedded within social networks and sustained by confidence in the motives of others—encourage and facilitate participation in civic life. This study tests and broadens these theses by (1) assessing the relative impact of different types of associational activities (i.e., informal socializing, public attendance, and religious participation) and (2) examining interactive relationships between these activities and generalized interpersonal trust. Findings show that all of these associational activities significantly contribute to civic engagement. Furthermore, all three interactions between the social associations and social trust are significant, indicating that those involved in associational activities are even more likely to become civic participants when they hold trusting attitudes toward others.
Epigenetic programming by early‐life stress: Evidence from human populations

Background: A substantial body of experimental and epidemiological evidence has been accumulated suggesting that stressful events in early life including acute perinatal stress, maternal deprivation or separation, and variation in maternal care may lead to neuroendocrine perturbations thereby affecting reproductive performance, cognitive functions, and stress responses as well as the risk for infectious, cardio‐metabolic and psychiatric diseases in later life. Results: Findings from recent studies based on both genome‐wide and candidate gene approaches highlighted the importance of mechanisms that are involved in epigenetic regulation of gene expression, such as DNA methylation, histone modifications, and non‐coding RNAs, in the long‐term effects of exposure to stress in early life. Conclusions: This review is focused on the findings from human studies indicating the role of epigenetic mechanisms in the causal link between early‐life stress and later‐life health outcomes. Developmental Dynamics 244:254–265, 2015. © 2014 Wiley Periodicals, Inc.
Attractive Faces Are Only Average

Scientists and philosophers have searched for centuries for a parsimonious answer to the question of what constitutes beauty. We approached this problem from both an evolutionary and information-processing rationale and predicted that faces representing the average value of the population would be consistently judged as attractive. To evaluate this hypothesis, we digitized samples of male and female faces, mathematically averaged them, and had adults judge the attractiveness of both the individual faces and the computer-generated composite images. Both male (three samples) and female (three samples) composite faces were judged as more attractive than almost all the individual faces comprising the composites. A strong linear trend also revealed that the composite faces became more attractive as more faces were entered. These data showing that attractive faces are only average are consistent with evolutionary pressures that favor characteristics close to the mean of the population and with cognitive processes that favor prototypical category members.
Performance analysis and redistribution among RIPv2, EIGRP & OSPF Routing Protocol

In a network topology, it is very usual to use various kinds of routing protocol for forwarding packets. A routing table is used in the memory of a router that keeps the track of routes to particular network destination and the most popular routing algorithms used to forward packets are Routing Information Protocol (RIPv2), Enhanced Interior Gateway Routing Protocol (EIGRP) and Open Shortest Path First (OSPF). The ultimate concentration of this research work is to depict the performance analysis comparison of these three dynamic routing protocols and redistribution among the protocols. Eight Cisco routers and a switch are used in our simulated network topology where four routers with different protocols directly connected with the switch take the responsibility for the redistribution algorithm.
Olfactometric and rhinomanometric outcomes in post-menopausal women treated with hormone therapy: a prospective study.

BACKGROUND The aim of this prospective study was to evaluate the effects of hormone therapy (HT) on olfactory sensitivity in post-menopausal women. METHODS Forty-six naturally post-menopausal women underwent rhinomanometric and olfactometric measurements to compare nasal airflow resistance values and olfactometric thresholds during the eighth month of HT treatment with baseline levels prior to starting HT. Eighteen women used an oral HT regimen, and twenty-eight women used transdermal patch HT. RESULTS Rhinomanometric values during HT were statistically differ from those at baseline (P < 0.001). Olfactometric threshold data indicated a higher sensitivity during the HT treatment than at baseline (P < 0.001). Finally, no statistically significant difference was observed among women using oral or patch HT administration on rhinomanometric and olfactometric values. CONCLUSIONS Our study demonstrates that 8 months of treatment with estrogen and progestogens in HT preparations has an effect on nasal airflow resistance and the olfactory thresholds to odours. We believe that estrogens could influence neuronal plasticity, and the neuronal conduction time into the olfactory system. Our findings confirm that gonadal steroids such as estrogen have an influence on non-genital targets; this relationship might have a beneficial impact on sensorineural communication and emotional behaviour.
Non-Intrusive Efficiency Determination of In-Service Induction Motors using Genetic Algorithm and Air-Gap Torque Methods

In-service testing poses particular difficulties for experimentally determining induction machine efficiency. This paper focuses on non-intrusive methods for testing in-service machines and proposes a hybrid method based on the air-gap torque method and genetic algorithms. The proposed method has been verified from the experimental results from three induction motors rated at 7.5 hp, 100 hp and 225 kW. The overall efficiency estimation accuracy is approximately within 4-5% errors.
Rating-Based Investment Practices and Bond Market Segmentation

This paper documents a new channel for rating-based bond market segmentation, which, in contrast to prior research, is based on nonregulatory investment management practices. A 2005 Lehman Brothers index redefinition provides a quasinatural experiment in which a number of previously high-yield split-rated bonds were mechanically relabeled as investment grade. Although their regulatory standing was unaffected, these bonds had abnormal yield declines of 21 basis points. These valuation changes can be traced to buying by asset-class-sensitive institutional investors for whom these bonds became investable. Reputation, regulation, indexation, and liquidity cannot explain the observed price and trading patterns.
No 2015:3 Closed Form Valuation of Three-Asset Spread Options With a view towards Clean Dark Spreads

We perform a slight generalization of the Bjerksund and Stensland (2011) spread option valuation formula to cover three-asset spread options. We investigate the pricing performance of the model against the corresponding version of the Kirk formula and the true price calculated with Monte Carlo methods. The numerical setting of the evaluation is designed to mimic a real market situation in the German OTC market for clean dark spread options. The results show that both models give similar and accurate price estimates (compared to the true option price). Comparing the performance between the models we conclude that the three-asset Bjerksund-Stensland formula performs marginally better compared to the three-asset Kirk formula (counting the number of test cases with the lowest absolute pricing error against the true option price).
Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence

Desmoplasia, a fibrotic mass including cancer-associated fibroblasts (CAFs) and self-sustaining extracellular matrix (D-ECM), is a puzzling feature of pancreatic ductal adenocarcinoma (PDACs). Conflicting studies have identified tumor-restricting and tumor-promoting roles of PDAC-associated desmoplasia, suggesting that individual CAF/D-ECM protein constituents have distinguishable tumorigenic and tumor-repressive functions. Using 3D culture of normal pancreatic versus PDAC-associated human fibroblasts, we identified a CAF/D-ECM phenotype that correlates with improved patient outcomes, and that includes CAFs enriched in plasma membrane-localized, active α5β1-integrin. Mechanistically, we established that TGFβ is required for D-ECM production but dispensable for D-ECM-induced naïve fibroblast-to-CAF activation, which depends on αvβ5-integrin redistribution of pFAK-independent active α5β1-integrin to assorted endosomes. Importantly, the development of a simultaneous multi-channel immunofluorescence approach and new algorithms for computational batch-analysis and their application to a human PDAC panel, indicated that stromal localization and levels of active SMAD2/3 and α5β1-integrin distinguish patient-protective from patient-detrimental desmoplasia and foretell tumor recurrences, suggesting a useful new prognostic tool. DOI: http://dx.doi. org/10.7554/eLife.20600. 001
Toxic-Selenium and Low-Selenium Transcriptomes in Caenorhabditis elegans: Toxic Selenium Up-Regulates Oxidoreductase and Down-Regulates Cuticle-Associated Genes

Selenium (Se) is an element that in trace quantities is both essential in mammals but also toxic to bacteria, yeast, plants and animals, including C. elegans. Our previous studies showed that selenite was four times as toxic as selenate to C. elegans, but that deletion of thioredoxin reductase did not modulate Se toxicity. To characterize Se regulation of the full transcriptome, we conducted a microarray study in C. elegans cultured in axenic media supplemented with 0, 0.05, 0.1, 0.2, and 0.4 mM Se as selenite. C. elegans cultured in 0.2 and 0.4 mM Se displayed a significant delay in growth as compared to 0, 0.05, or 0.1 mM Se, indicating Se-induced toxicity, so worms were staged to mid-L4 larval stage for these studies. Relative to 0.1 mM Se treatment, culturing C. elegans at these Se concentrations resulted in 1.9, 9.7, 5.5, and 2.3%, respectively, of the transcriptome being altered by at least 2-fold. This toxicity altered the expression of 295 overlapping transcripts, which when filtered against gene sets for sulfur and cadmium toxicity, identified a dataset of 182 toxic-Se specific genes that were significantly enriched in functions related to oxidoreductase activity, and significantly depleted in genes related to structural components of collagen and the cuticle. Worms cultured in low Se (0 mM Se) exhibited no signs of deficiency, but low Se was accompanied by a transcriptional response of 59 genes changed ≥2-fold when compared to all other Se concentrations, perhaps due to decreases in Se-dependent TRXR-1 activity. Overall, these results suggest that Se toxicity in C. elegans causes an increase in ROS and stress responses, marked by increased expression of oxidoreductases and reduced expression of cuticle-associated genes, which together underlie the impaired growth observed in these studies.
THE DARK HALO—SPHEROID CONSPIRACY AND THE ORIGIN OF ELLIPTICAL GALAXIES

Dynamical modeling and strong-lensing data indicate that the total density profiles of early-type galaxies are close to isothermal, i.e., ρtot∝rγ with γ ≈ −2. To understand the origin of this universal slope we study a set of simulated spheroids formed in isolated binary mergers as well as the formation within the cosmological framework. The total stellar plus dark matter density profiles can always be described by a power law with an index of γ ≈ −2.1 with a tendency toward steeper slopes for more compact, lower-mass ellipticals. In the binary mergers the amount of gas involved in the merger determines the precise steepness of the slope. This agrees with results from the cosmological simulations where ellipticals with steeper slopes have a higher fraction of stars formed in situ. Each gas-poor merger event evolves the slope toward γ ∼ −2, once this slope is reached further merger events do not change it anymore. All our ellipticals have flat intrinsic combined stellar and dark matter velocity dispersion profiles. We conclude that flat velocity dispersion profiles and total density distributions with a slope of γ ∼ −2 for the combined system of stars and dark matter act as a natural attractor. The variety of complex formation histories as present in cosmological simulations, including major as well as minor merger events, is essential to generate the full range of observed density slopes seen for present-day elliptical galaxies.