Miracle-dz/UniFAR-FTUs huggingface dataset:
Autogynephilia and the typology of male-to-female transsexualism: Concepts and controversies.

Abstract. Sexual scientists have recognized for over a century that biologic males who seek sex reassignment – male-to-female (MtF) transsexuals – are not a homogeneous clinical population but comprise two or more distinct subtypes with different symptoms and developmental trajectories. The most widely used typologies of MtF transsexualism have been based on sexual orientation and have distinguished between persons who are androphilic (exclusively sexually attracted to males) and those who are nonandrophilic (sexually attracted to females, both males and females, or neither gender). In 1989, psychologist Ray Blanchard proposed that most nonandrophilic MtF transsexuals display a paraphilic sexual orientation called autogynephilia, defined as the propensity to be sexually aroused by the thought or image of oneself as a woman. Studies conducted by Blanchard and colleagues provided empirical support for this proposal, leading to the hypothesis that almost all nonandrophilic MtF transsexuals are autogynephilic.
ISMIR 2004 Audio Description Contest

In this paper we report on the ISMIR 2004 Audio Description Contest. We first detail the contest organization, evaluation metrics, data and infrastructure. We then provide the details and results of each contest in turn. Published papers and algorithm source codes are given when originally available. We finally discuss some aspects of these contests and propose ways to organize future, improved, audio description contests.
PENGARUH ORGANIZATIONAL TRUST DAN JOB SATISFACTION TERHADAP EMPLOYEE ENGAGEMENT PADA KARYAWAN PT. BANGUN WISMA SEJAHTERA

Keberhasilan dalam mencapai tujuan perusahaan dipengaruhi oleh faktor sumber daya manusia, yaitu karyawan. Terdapat beberapa faktor yang mempengaruhi keterikatan karyawan pada perusahaan, yaitu kepercayaan dan kepuasan kerja karyawan terhadap perusahaan. Tujuan penelitian ini adalah untuk mengetahui pengaruh organizational trust dan job satisfaction terhadap Employee Engagement pada karyawan PT Bangun Wisma Sejahtera. Jenis penelitian ini adalah pendekatan kuantitatif. Penelitian ini menggunakan sampel sejumlah 47 karyawan. Teknik pengambilan sampel menggunakan sampling jenuh . Metode pengumpulan data berupa kuesioner dan teknik analisis data menggunakan analisis regresi linier berganda dengan alat bantu program IBM SPSS Statistics versi 20. Hasil penelitian ini menunjukkan bahwa organizational trust dan job satisfaction berpengaruh signifikan terhadap employee engagement karyawan PT Bangun Wisma Sejahtera baik secara parsial maupun simultan.
The effect of sports specific training on reducing the incidence of hamstring injuries in professional Australian Rules football players

Objectives: To assess in a single team of Australian Rules football players the effect of a specific intervention program on the incidence and consequence of hamstring muscle strain injuries. Method: A prospective study was performed with a single team being followed for four playing seasons for hamstring injury. Magnetic resonance imaging was used to confirm the diagnosis of hamstring muscle injury. After two playing seasons an intervention program was implemented with the number of athletes with hamstring injury, competition days missed, and incidence of hamstring match injuries per 1000 h of playing time being compared pre- and post-intervention. The intervention program involved stretching whilst fatigued, sport specific training drills, and an emphasis on increasing the amount of high intensity anaerobic interval training. Results: In the seasons prior to the intervention, nine and 11 athletes sustained hamstring injury compared to two and four following intervention. Competition days missed reduced from 31 and 38 to 5 and 16 following intervention and match incidence decreased from 4.7 to 1.3 per 1000 h of playing time. A beneficial effect was demonstrated with a smaller number of players having hamstring injuries (p = 0.05), a lower number of competition games missed being recorded (p<0.001), and a decrease in hamstring strain incidence per 1000 h of playing time (p = 0.01) following the intervention program. Conclusions: Increasing the amount of anaerobic interval training, stretching whilst the muscle is fatigued, and implementing sport specific training drills resulted in a significant reduction in the number and consequences of hamstring muscle strain injuries.
Agglomeration-Effects in Europe

The paper estimates agglomeration-effects for France, Germany, Italy, Spain, and the UK. Estimation takes into account endogeneity of the spatial distribution of employment and spatial fixed-effects. Empirical results suggest that agglomeration-effects in these European countries are only slightly smaller than agglomeration- effects in the US: the estimated elasticity of average- labor-productivity with respect to employment-density is 4.5 percent compared to 5 percent in the US.
Assessment of dental students’ communication skills with patients

Introduction Establishment of effective communication between the clinician and patient is essential in order to increase the effectiveness of treatment. These skills have been less investigated among dental students. This study aimed to evaluate communication skills of dental students in Shiraz with patients through direct observation, patients' perspectives and students' self-assessments. Methods This cross-sectional study enrolled the fifth and sixth year dental students and one of each student’s patients who was chosen using simple random sampling method. We used a checklist for data collection. Students’ communication skills were assessed at three steps of the student-patient interview – at the beginning of the interview, during the interview, and at the end of the interview. The checklist was completed by three groups: 1) an observer, 2) the patient and 3) the student, as self-assessment. The validity of the checklist was confirmed by clinical professors and the reliability was determined by Cronbach's alpha test. Data were analyzed using descriptive statistics and Student’s t test. A repeated measure MANOVA was used to compare the mean communication skills in the researcher, patients, and students at each step of the patient interviews. Results There were 110 students (mean age: 22.3±8.4 years) and 110 patients (mean age: 32±8.8 years) who completed the checklists. Overall, the communication skills of dental students were rated as good according to the patients. However, the observer and student participants rated the skills at the moderate level. We observed significant differences between communication skills in all three groups and in the three steps of the patient interviews (p<0.001). According to patients' beliefs and students' self assessments, there were no differences between male and female students in communication skills in the three steps of the patient interviews (all p>0.05). However from the observer’s viewpoint, female students showed better communication skills during the interviews (p=0.001). Conclusion There was a degree of failure in communication skills of dental students with patients in the interview process. It will be necessary that communication skills be taught, particularly for students involved in clinical practice.
Applying Differential Privacy to Matrix Factorization

Recommender systems are increasingly becoming an integral part of on-line services. As the recommendations rely on personal user information, there is an inherent loss of privacy resulting from the use of such systems. While several works studied privacy-enhanced neighborhood-based recommendations, little attention has been paid to privacy preserving latent factor models, like those represented by matrix factorization techniques. In this paper, we address the problem of privacy preserving matrix factorization by utilizing differential privacy, a rigorous and provable privacy preserving method. We propose and study several approaches for applying differential privacy to matrix factorization, and evaluate the privacy-accuracy trade-offs offered by each approach. We show that input perturbation yields the best recommendation accuracy, while guaranteeing a solid level of privacy protection.
Sequential Recall and American Sign Language: A Look at LOT

Abstract:This article investigates the sequential recall of manual alphabet letters by signing deaf adolescents under two presentation conditions: fingerspelling and the listing and ordering technique (LOT) of American Sign Language. Fingerspelling presents each letter in a manner similar to the spelling of spoken words: A letter is produced and then is no longer available as the next letter in the sequence is produced. In addition, LOT allows for a letter to be presented on one hand and referenced to a finger on the other, nonmoving hand, providing a visuospatial anchor for the item. Recall of LOT- presented items proved superior to that of fingerspelled presentations.
A quantitative method to evaluate mesenchymal stem cell lipofection using real‐time PCR

Genetic modification of human mesenchymal stem cells (MSC) is a powerful tool to improve the therapeutic utility of these cells and to increase the knowledge on their regulation mechanisms. In this context, strong efforts have been made recently to develop efficient nonviral gene delivery systems. Although several studies addressed this question most of them use the end product of a reporter gene instead of the DNA uptake quantification to test the transfection efficiency. In this study, we established a method based on quantitative real‐time PCR (RT‐PCR) to determine the intracellular plasmid DNA copy number in human MSC after lipofection. The procedure requires neither specific cell lysis nor DNA purification. The influence of cell number on the RT‐PCR sensitivity was evaluated. The method showed good reproducibility, high sensitivity, and a wide linear range of 75–2.5 × 106 plasmid DNA copies per cell. RT‐PCR results were then compared with the percentage of transfected cells assessed by flow cytometry analysis, which showed that flow cytometry‐based results are not always proportional to plasmid cellular uptake determined by RT‐PCR. This work contributed for the establishment of a rapid quantitative assay to determine intracellular plasmid DNA in stem cells, which will be extremely beneficial for the optimization of gene delivery strategies. © 2010 American Institute of Chemical Engineers Biotechnol. Prog. , 2010
PSD-95 Assembles a Ternary Complex with theN-Methyl-d-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain*

Nitric oxide (NO) biosynthesis in cerebellum is preferentially activated by calcium influx throughN-methyl-d-aspartate (NMDA)-type glutamate receptors, suggesting that there is a specific link between these receptors and neuronal NO synthase (nNOS). Here, we find that PSD-95 assembles a postsynaptic protein complex containing nNOS and NMDA receptors. Formation of this complex is mediated by the PDZ domains of PSD-95, which bind to the COOH termini of specific NMDA receptor subunits. In contrast, nNOS is recruited to this complex by a novel PDZ-PDZ interaction in which PSD-95 recognizes an internal motif adjacent to the consensus nNOS PDZ domain. This internal motif is a structured “pseudo-peptide” extension of the nNOS PDZ that interacts with the peptide-binding pocket of PSD-95 PDZ2. This asymmetric interaction leaves the peptide-binding pocket of the nNOS PDZ domain available to interact with additional COOH-terminal PDZ ligands. Accordingly, we find that the nNOS PDZ domain can bind PSD-95 PDZ2 and a COOH-terminal peptide simultaneously. This bivalent nature of the nNOS PDZ domain further expands the scope for assembly of protein networks by PDZ domains.
Effects of dark matter substructures on gravitational lensing: results from the Aquarius simulations

We use the high-resolution Aquarius simulations of the formation of Milky Way-sized haloes in the Λ cold dark matter cosmology to study the effects of dark matter substructures on gravitational lensing. Each halo is resolved with ∼108 particles (at a mass resolution mp∼ 103 to 104 h−1 M⊙) within its virial radius. Subhaloes with masses msub≳ 105 h−1 M⊙ are well resolved, an improvement of at least two orders of magnitude over previous lensing studies. We incorporate a baryonic component modelled as a Hernquist profile and account for the response of the dark matter via adiabatic contraction. We focus on the ‘anomalous’ flux ratio problem, in particular on the violation of the cusp–caustic relation due to substructures. We find that subhaloes with masses less than ∼108 h−1 M⊙ play an important role in causing flux anomalies; such low-mass subhaloes have been unresolved in previous studies. There is large scatter in the predicted flux ratios between different haloes and between different projections of the same halo. In some cases, the frequency of predicted anomalous flux ratios is comparable to that observed for the radio lenses, although in most cases it is not. The probability for the simulations to reproduce the observed violations of the cusp lenses is ≈10−3. We therefore conclude that the amount of substructure in the central regions of the Aquarius haloes is insufficient to explain the observed frequency of violations of the cusp–caustic relation. These conclusions are based purely on our dark matter simulations which ignore the effect of baryons on subhalo survivability.
The Potential of Diffusive Load Balancing at Large Scale

Dynamic load balancing with diffusive methods is known to provide minimal load transfer and requires communication between neighbor nodes only. These are very attractive properties for highly parallel systems. We compare diffusive methods with state-of-the-art geometrical and graph-based partitioning methods on thousands of nodes. When load balancing overheads, i.e. repartitioning computation time and migration, have to be minimized, diffusive methods provide substantial benefits.
Compressed sensing for Synthetic Aperture Radar imaging

In this paper, we introduce a new Synthetic Aperture Radar (SAR) imaging modality that provides a high resolution map of the spatial distribution of targets and terrain based on a significant reduction in the number of transmitted and/or received electromagnetic waveforms. This new imaging scheme, which requires no new hardware components, allows the aperture to be compressed and presents many important applications and advantages among which include resolving ambiguities, strong resistance to countermesasures and interception, and reduced on-board storage constraints.
Heat Sensing Receptor TRPV1 Is a Mediator of Thermotaxis in Human Spermatozoa

The molecular bases of sperm thermotaxis, the temperature-oriented cell motility, are currently under investigation. Thermal perception relies on a subclass of the transient receptor potential [TRP] channels, whose member TRPV1 is acknowledged as the heat sensing receptor. Here we investigated the involvement of TRPV1 in human sperm thermotaxis. We obtained semen samples from 16 normozoospermic subjects attending an infertility survey programme, testis biopsies from 6 patients with testicular germ cell cancer and testis fine needle aspirates from 6 patients with obstructive azoospermia undergoing assisted reproductive technologies. Expression of TRPV1 mRNA was assessed by RT-PCR. Protein expression of TRPV1 was determined by western blot, flow cytometry and immunofluorescence. Sperm motility was assessed by Sperm Class Analyser. Acrosome reaction, apoptosis and intracellular-Ca2+ content were assessed by flow cytometry. We found that TRPV1 mRNA and protein were highly expressed in the testis, in both Sertoli cells and germ-line cells. Moreover, compared to no-gradient controls at 31°C or 37°C (Ctrl 31°C and Ctrl 37°C respectively), sperm migration towards a temperature gradient of 31–37°C (T gradient) in non-capacitated conditions selected a higher number of cells (14,9 ± 4,2×106 cells T gradient vs 5,1± 0,3×106 cells Ctrl 31°C and 5,71±0,74×106 cells Ctrl 37°C; P = 0,039). Capacitation amplified the migrating capability towards the T gradient. Sperms migrated towards the T gradient showed enriched levels of both TRPV1 protein and mRNA. In addition, sperm cells were able to migrate toward a gradient of capsaicin, a specific agonist of TRPV1, whilst capsazepine, a specific agonist of TRPV1, blocked this effect. Finally, capsazepine severely blunted migration towards T gradient without abolishing. These results suggest that TRPV1 may represent a facilitating mediator of sperm thermotaxis.
Effects of Acupuncture Stimulation at Different Acupoints on Formalin-Induced Pain in Rats

Acupuncture is the process of stimulating skin regions called meridians or acupoints and has been used to treat pain-related symptoms. However, the pain-relieving effects of acupuncture may be different depending on acupoints. In the present study, the effects of acupuncture on behavioral responses and c-Fos expression were evaluated using a formalin test in male Sprague-Dawley rats in order to clarify the analgesic effects of three different acupoints. Each rat received manual acupuncture at the ST36 (Zusanli), SP9 (Yinlingquan) or BL60 (Kunlun) acupoint before formalin injection. Flinching and licking behaviors were counted by two blinded investigators. Fos-like immunoreactivity was examined by immunohistochemistry in the rat spinal cord. Manual acupuncture treatment at BL60 acupoint showed significant inhibition in flinching behavior but not in licking. Manual acupuncture at ST36 or SP9 tended to inhibit flinching and licking behaviors but the effects were not statistically significant. The acupuncture at ST36, SP9, or BL60 reduced c-Fos expression as compared with the control group. These results suggest that acupuncture especially at the BL60 acupoint is more effective in relieving inflammatory pain than other acupoints.
Can Distrust Enhance Public Engagement? Insights From a National Survey on Energy Issues in Canada

ABSTRACT Research examining the relationship between trust, public engagement, and natural resource management asserts that trust fosters positive behavior and enhanced cooperation. Yet some scholars are finding that certain kinds of distrust are helpful in achieving democratic outcomes by providing would-be participants with the motivation to engage in issues of public concern. This article seeks to clarify this apparent disjuncture in the trust literature by examining the multidimensional nature of trust as it relates to public engagement on energy-related issues in Canada. Based on a national online survey (n = 3000) we use a binary probit model to explore the connections between trust, knowledge, and public engagement. About 70% of respondents had participated in at least one form of public engagement over the last 3 years. Drawing on a two-dimensional conception of trust, we find that general trust on its own is not positively linked to public engagement. A combination of general trust and skepticism, however, is positively associated with public engagement and confirms our hypothesis that at least some concern regarding credibility, bias, and vested interest can motivate public engagement. In this sense, trust is not uniformly good for public engagement. These results signal a need to further refine our assumptions about the relationship between public trust, public engagement and environmental governance.
Exploring the Influence of Trust on Mobile Payment Adoption

The objective of this study is to explore antecedents of trust and the influence of trust on intention to use mobile payments. The research examines three dimensions of trust antecedents including trust perceptions of the mobile service provider, the mobile payment vendor and mobile technology. The results are based on a survey sample of 302 participants. PLS-SEM is employed in the data analysis. Results reveal that trust is a crucial factor of consumer’s intention to adopt mobile payment. Results highlight that characteristics of the mobile service provider, mobile payment vendor and mobile technology influence the development of trust on mobile payment. In particular, consumer’s perceptions of structural assurance and environmental risks of mobile technology have strong influence on mobile payment trust. Results also highlight that consumers’ perceived reputation of the mobile service provider and mobile payment vendor positively relate to mobile payment trust.
Feedbacks and responses of coral calcification on the Bermuda reef system to seasonal changes in biological processes and ocean acidification

Abstract. Despite the potential impact of ocean acidification on ecosystems such as coral reefs, surprisingly, there is very limited field data on the relationships between calcification and seawater carbonate chemistry. In this study, contemporaneous in situ datasets of seawater carbonate chemistry and calcification rates from the high-latitude coral reef of Bermuda over annual timescales provide a framework for investigating the present and future potential impact of rising carbon dioxide (CO2) levels and ocean acidification on coral reef ecosystems in their natural environment. A strong correlation was found between the in situ rates of calcification for the major framework building coral species Diploria labyrinthiformis and the seasonal variability of [CO32-] and aragonite saturation state Ωaragonite, rather than other environmental factors such as light and temperature. These field observations provide sufficient data to hypothesize that there is a seasonal "Carbonate Chemistry Coral Reef Ecosystem Feedback" (CREF hypothesis) between the primary components of the reef ecosystem (i.e., scleractinian hard corals and macroalgae) and seawater carbonate chemistry. In early summer, strong net autotrophy from benthic components of the reef system enhance [CO32-] and Ωaragonite conditions, and rates of coral calcification due to the photosynthetic uptake of CO2. In late summer, rates of coral calcification are suppressed by release of CO2 from reef metabolism during a period of strong net heterotrophy. It is likely that this seasonal CREF mechanism is present in other tropical reefs although attenuated compared to high-latitude reefs such as Bermuda. Due to lower annual mean surface seawater [CO32-] and Ωaragonite in Bermuda compared to tropical regions, we anticipate that Bermuda corals will experience seasonal periods of zero net calcification within the next decade at [CO32-] and Ωaragonite thresholds of ~184 μmoles kg−1 and 2.65. However, net autotrophy of the reef during winter and spring (as part of the CREF hypothesis) may delay the onset of zero NEC or decalcification going forward by enhancing [CO32-] and Ωaragonite. The Bermuda coral reef is one of the first responders to the negative impacts of ocean acidification, and we estimate that calcification rates for D. labyrinthiformis have declined by >50% compared to pre-industrial times.