Miracle-dz/UniFAR-FTUs huggingface dataset:
A study on extruded filament bonding in fused filament fabrication

Purpose The performance of parts produced by fused filament fabrication is directly related to the printing conditions and to the rheological phenomena inherent to the process, specifically the bonding between adjacent extruded paths/raster. This paper aims to study the influence of a set of printing conditions and parameters, namely, envelope temperature, extrusion temperature, forced cooling and extrusion rate, on the parts performance. Design/methodology/approach The influence of these parameters is evaluated by printing a set of test specimens that are morphologically characterized and mechanically tested. At the morphological level, the external dimensions and the voids content of the printed specimens are evaluated. The bonding quality between adjacent extruded paths is assessed through the mechanical performance of test specimens, subjected to tensile loads. These specimens are printed with all raster oriented at 90º relative to the tensile axis. Findings The best performance, resulting from a compromise between surface quality, dimensional accuracy and mechanical performance, is achieved with a heated printing environment and with no use of forced cooling. In addition, for all the conditions tested, the highest dimensional accuracy is achieved in dimensions defined in the printing plane. Originality/value This work provides a relevant result as the majority of the current printers comes without enclosure or misses the heating and envelope temperature control systems, which proved to be one of the most influential process parameter.
A Review of the Opinion Target Extraction using Sequence Labeling Algorithms based on Features Combinations

In recent years, the opinion analysis is one of the key research fronts of any domain. Opinion target extraction is an essential process of opinion analysis. Target is usually referred to noun or noun phrase in an entity which is deliberated by the opinion holder. Extraction of opinion target facilitates the opinion analysis more precisely and in addition helps to identify the opinion polarity i.e. users can perceive opinion in detail of a target including all its features. One of the most commonly employed algorithms is a sequence labeling algorithm also called Conditional Random Fields. In present article, recent opinion target extraction approaches are reviewed based on sequence labeling algorithm and it features combinations by analyzing and comparing these approaches. The good selection of features combinationswill in some way give a good or better accuracy result. Features combinations are an essential process thatcan be used to identify and remove unneeded, irrelevant and redundant attributes from data that do not contribute to the accuracy of a predictive model or may in fact decrease the accuracy of the model.Hence, in general this review eventually leads to the contribution for the opinion analysis approach and assist researcher for the opinion target extraction in particular. ☞ keyword : Features Combinations, Opinion Target Extraction, Text sentiment analysis, Conditional Random Field and Sequence Labeling Algorithm
miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer

MicroRNA (miRNA) dysfunction is associated with a variety of human diseases, including cancer. Our previous study showed that miR-671-5p was deregulated throughout breast cancer progression. Here, we report for the first time that miR-671-5p is a tumor-suppressor miRNA in breast tumorigenesis. We found that expression of miR-671-5p was decreased significantly in invasive ductal carcinoma (IDC) compared to normal in microdissected formalin-fixed, paraffin-embedded (FFPE) tissues. Forkhead Box M1 (FOXM1), an oncogenic transcription factor, was predicted as one of the direct targets of miR-671-5p, which was subsequently confirmed by luciferase assays. Forced expression of miR-671-5p in breast cancer cell lines downregulated FOXM1 expression, and attenuated the proliferation and invasion in breast cancer cell lines. Notably, overexpression of miR-671-5p resulted in a shift from epithelial-to-mesenchymal transition (EMT) to mesenchymal-to-epithelial transition (MET) phenotypes in MDA-MB-231 breast cancer cells and induced S-phase arrest. Moreover, miR-671-5p sensitized breast cancer cells to cisplatin, 5-fluorouracil (5-FU) and epirubicin exposure. Host cell reactivation (HCR) assays showed that miR-671-5p reduces DNA repair capability in post-drug exposed breast cancer cells. cDNA microarray data revealed that differentially expressed genes when miR-671-5p was transfected are associated with cell proliferation, invasion, cell cycle, and EMT. These data indicate that miR-671-5p functions as a tumor suppressor miRNA in breast cancer by directly targeting FOXM1. Hence, miR-671-5p may serve as a novel therapeutic target for breast cancer management.
Contribution of Substance P and Neurokinin A to the Differential Injury-Induced Thermal and Mechanical Responsiveness of Lamina I and V Neurons

In a previous report, we compared the properties of lamina V neurons of the spinal cord dorsal horn in wild-type mice and in mice with a deletion of the preprotachykinin-A (PPT-A) gene, which encodes substance P (SP) and neurokinin A (NKA). The mutant mice had pronounced deficits in the response to thermal stimulation, both before and after mustard oil induced sensitization. Here, we extended our analysis to the properties of lamina I neurons and also examined responsiveness to mechanical stimulation. Consistent with the properties of lamina V neurons, in the PPT-A mutant mice we found significantly reduced responses of lamina I neurons to noxious thermal stimulation, and mustard oil sensitization of these neurons to heat was lost. In contrast, not only were the responses of lamina I neurons to noxious mechanical stimulation unchanged in the mutant mice, but in neither the wild-type nor the mutant mice could sensitization be induced. However, mustard oil profoundly sensitized lamina V neurons to mechanical stimulation in both wild-type and mutant mice. We conclude that SP and/or NKA are required for the transmission of noxious thermal stimulation by lamina I and V neurons, both before and after tissue injury. The persistence of mechanical sensitization of lamina V neurons in the mutant mice further shows that mustard oil induces mechanical and thermal sensitization through different mechanisms. Finally, we conclude that lamina I sensitization to mechanical stimulation is not required for this form of injury-increased responsiveness of lamina V neurons.
TREC 2013 Microblog Track Experiments at Kobe University

This paper describes our approach to real-time ad hoc task processing in the TREC 2013 microblog track. The approach uses a concept-based query expansion method based on a temporal relevance model that uses the temporal variation of concepts (e.g. terms or phrases) on microblogs. Our model extends an effective existing word and concept-based relevance models by tracking the concept frequency over time in microblogging services. The experimentally ob- tained results demonstrate that our concept-based query expansion method im- prove search performance, especially when using tweet selection feedback.
Neural Correlates of Variations in Event Processing during Learning in Basolateral Amygdala

The discovery that dopamine neurons signal errors in reward prediction has demonstrated that concepts empirically derived from the study of animal behavior can be used to understand the neural implementation of reward learning. Yet the learning theory models linked to phasic dopamine activity treat attention to events such as cues and rewards as static quantities; other models, such as Pearce–Hall, propose that learning might be influenced by variations in processing of these events. A key feature of these accounts is that event processing is modulated by unsigned rather than signed reward prediction errors. Here we tested whether neural activity in rat basolateral amygdala conforms to this pattern by recording single units in a behavioral task in which rewards were unexpectedly delivered or omitted. We report that neural activity at the time of reward is providing an unsigned error signal with characteristics consistent with those postulated by these models. This neural signal increased immediately after a change in reward, and stronger firing was evident whether the value of the reward increased or decreased. Further, as predicted by these models, the change in firing developed over several trials as expectations for reward were repeatedly violated. This neural signal was correlated with faster orienting to predictive cues after changes in reward, and abolition of the signal by inactivation of basolateral amygdala disrupted this change in orienting and retarded learning in response to changes in reward. These results suggest that basolateral amygdala serves a critical function in attention for learning.
Plasmonic Structure Integrated Single-Photon Detectors Optimized to Maximize Polarization Contrast

Numerical optimization was performed via COMSOL multiphysics to maximize the polarization contrast of superconducting nanowire single photon detectors (SNSPDs). SNSPDs were integrated with four different types of 1D periodic plasmonic structures capable of mediating p-polarized photon selectivity to the niobium-nitride superconducting nanowire pattern. Optimization with two different criteria regarding the maximal tilting resulted in wavelength-scaled periodic integrated structures, which have different geometrical parameters, and exhibit different polar angle dependent optical responses and dispersion characteristics, as well as accompanying near-field phenomena at the extrema. Polarization contrast of 6.4·10<sup>2</sup> and 3.3·10<sup>2</sup>/6.9·10<sup> 11</sup> and 1.4·10<sup>11</sup>/1.8·10<sup>13</sup> and 7.9·10<sup>12</sup>/1.9·10 <sup>3</sup> and 1.2·10<sup>5</sup> can be achieved in nanocavity-/nanocavity-deflector-/nanocavity-double-deflector-/nanocavity-trench-array-integrated P-SNSPDs optimized with 85° and 80° criterion, regarding the maximal tilting.
On the Horizontal Deviation of a Spinning Projectile Penetrating into Granular Systems

The absence of a general theory that describes the dynamical behavior of the particulate materials makes the numerical simulations the most current powerful tool that can grasp many mechanical problems relevant to the granular materials. In this paper, based on a two-dimensional soft particle discrete element method (DEM), a numerical approach is developed to investigate the consequence of the orthogonal impact into various granular beds of projectile rotating in both clockwise (CW) and counterclockwise (CCW) directions. Our results reveal that, depending on the rotation direction, there is a significant deviation of the -coordinate of the final stopping point of a spinning projectile from that of its original impact point. For CW rotations, a deviation to the right occurs while a left deviation has been recorded for CCW rotation case.
Ant colony optimization with local search applied to the Flexible Job Shop Scheduling Problems

Flexible job-shop scheduling problem known as FJSSP is a NP-hard problem which attracts great attentions from researchers for decades. In this paper, a new approach of ant colony optimization with local search (ACOLS) is presented to solve the FJSSP. In the ACOLS, a new heuristic information is designed to balance the workloads between machines while ants tend to select the machine with less processing time for those operations. SPT scheduling rule is used to sequence the operations on each machine. In each iteration, a designed local search is used to search the neighborhood of the optimal solution obtained in each iteration for possible better solutions by the criterions of less total workloads and their variance for all machines. Simulation results show that the proposed ACOLS is very efficient compared with the basic ACO and other algorithms to deal with FJSSP.
An Extension of the Moser-Tardos Algorithmic Local Lemma

A recent theorem of Bissacot, et al. proved using results about the cluster expansion in statistical mechanics extends the Lov\'asz Local Lemma by weakening the conditions under which its conclusions holds. In this note, we prove an algorithmic analog of this result, extending Moser and Tardos's recent algorithmic Local Lemma, and providing an alternative proof of the theorem of Bissacot, et al. applicable in the Moser-Tardos algorithmic framework.
Physical activity and sedentary behavior in patients with systemic lupus erythematosus and rheumatoid arthritis

Objective Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are at increased risk of cardiovascular disease (CVD). As sedentary behavior and lack of physical activity are known cardiovascular risk factors, we compared habitual activity between SLE patients, RA patients, and healthy control participants. Patients and methods For this cross-sectional study, RA and SLE patients were recruited from rheumatology clinics at an academic medical center from April 2013 to December 2014. Healthy control participants were recruited through local advertising during the same time period. Habitual activity was measured using a triaxial accelerometer worn during waking hours for 7 consecutive days. Minutes per day of sedentary, light, and moderate–vigorous physical activity (MVPA) were recorded and compared between SLE, RA, and healthy participants using ANOVA. Results There were 59 participants included in the analysis: 20 SLE patients, 19 RA patients, and 20 healthy controls. Disease activity was quiescent in both the SLE and RA groups. All three groups demonstrated high sedentary behavior (mean ± SD sedentary time for all participants: 10.1±1.3 hours/day; 76.4% total wear time). There were no significant differences between SLE, RA, and healthy participants in time spent in sedentary behavior (p=0.80) or light activity (p=0.17). Total MVPA (mean ± SD, minutes/day) was significantly lower in SLE (34.5±22.7; p<0.001) and RA (41.5±21.3; p=0.005) patients compared to controls (64.9±22.4). Conclusion SLE and RA patients demonstrate suboptimal MVPA despite well-controlled disease. Given their increased CVD risk, effective interventions are required to improve habitual physical activity levels in both populations.
Thermochemoradiotherapy Improves Oxygenation in Locally Advanced Breast Cancer

Purpose: The purpose of this research was to evaluate toxicity, response, and changes in oxygenation (pO2) in patients with locally advanced breast cancer (LABC) treated with concurrent taxol, hyperthermia (HT), and radiation therapy (RT) followed by mastectomy. Experimental Design: Eighteen patients with LABC were enrolled from October 1995 through February 1999. Treatment consisted of taxol (175 mg/m2) given every 3 weeks for three cycles. Radiation therapy included the breast and regional nodes with a dose of 50 Gy, followed by a boost to 60–65 Gy for those not undergoing surgery. Mastectomy was performed for patients deemed resectable after this neoadjuvant program. HT was administered twice per week. Oxygenation was measured before the first HT treatment and 24 h after the first HT treatment. Results: Fifteen of 18 patients responded, 6 with a clinical complete response, 9 with a partial clinical response, and 3 nonresponders. Thirteen underwent mastectomy with 3 pathological complete responses. Tumor hypoxia was present in 8 of 13 patients (pO2 = 4.7 ± 1.2 mmHg). Five patients had well-oxygenated tumors (pO2 = 27.6 ± 7.8 mmHg). Patients with well-oxygenated tumors before treatment as well as those with significant reoxygenation had a favorable clinical response. Tumor reoxygenation appeared to be temperature dependent and associated with the lower thermal doses. Conclusions: This novel therapeutic program resulted in a high response rate in patients with LABC. Hyperthermia may offer a strategy for improving tumor reoxygenation with consequent treatment response. However, the effect of hyperthermia on tumor reoxygenation appears to depend on thermal dose and requires additional investigation.
Assessment and Determinants of Spinal Pain in the Course of Disc Disorders Treated Surgically

Background Intervertebral disc disease is defined as a complex of structural changes in the aftermath of disorders of mutual elements, the structure of which form the discus intervertebralis and the spinal canal. The present work assessed pain in patients who were surgically treated due to spinal discopathy and analyzed factors that determine the condition. Material/Methods The research was carried on a group of 187 patients diagnosed with discopathy of the lumbosacral and cervical segment. The data are discussed in the context of medical records and the Visual Analogue Scale used for pain assessment. We used a prospective study plan with a 3-time assessment. Results The pain level observed among patients prior to the procedure (M=6.52) was higher than after 7 days (M=3.15) and 6 months from the operation (M= 3.45). The highest level of pain (M=6.88), with a relatively high consistency among the patients (SD=2.25), was observed in the case of left-side hernia (H=7.31; p=0.023). The influence of the analyzed factors on pain experience markedly increased by the third assessment (R2=0.14), and was strongly associated with the type of work performed by the patient. Conclusions Surgical operation significantly reduces pain in patients with disc disorders. The level of pain is predominantly affected by the location of the hernia and the type of work performed by the patient.
Evaluation of IgA measurements as a method for detecting maternal blood contamination of cord blood samples

Several studies have evaluated the value of cord blood IgE concentrations for predicting the risk of allergic disease in children. In all of these studies it is necessary to exclude cord blood samples in which the IgE may be falsely elevated due to admixing of maternal and fetal blood during parturition. The most common method for detecting mixing of fetal and maternal blood is measurement of cord blood IgA concentrations. We have examined the theoretical basis of IgA measurements for detecting maternal blood contamination and reexamined our own data to evaluate IgA measurements. Our data suggest that the average IgA concentration of 28. 2 μg/ml used in previous studies may not adequately exclude contaminated cord blood sample. Failure to reject contaminated cord blood samples would reduce the positive predictive value of cord btood IgE measurements.
Methods for Lower Approximation Reduction in Inconsistent Decision Table Based on Tolerance Relation

It is well known that most of information systems are based on tolerance relation instead of the classical equivalence relation because of various factors in real-world. To acquire brief decision rules from the information systems, lower approximation reduction is needed. In this paper, the lower approximation reduction is proposed in inconsistent information systems based on tolerance relation. Moreover, the properties are discussed. Furthermore, judgment theorem and discernibility matrix are obtained, from which an approach to lower reductions can be provided in the complicated information systems.
An Evaluation of Induction Machine Stray Load Loss From Collated Test Results

The international standards for determining induction motor efficiency are not in agreement with each other. At the heart of the differences is the stray load loss (SLL). The way this loss is quantified is continuously debated. For many years, the IEC standard for motor efficiency measurement has assigned a fixed percentage to stray load loss. This fixed percentage value has been criticized throughout the history of the standard. A new version of the standard published in September 2007 replaced the fixed percentage with one that is dependent on motor kW rating through a specific relationship. One of the goals of this paper is to determine whether the new formula for assigning the SLL can be confirmed with actual test data. This paper presents a collection of test data on about 1000 motors to show the distribution of stray load losses in induction motors. The analysis clearly demonstrates the need for determining stray loss from test measurements rather than assigning an arbitrary value.
German wine in an American bottle: the spread of modern psychiatry in China, 1898–1949

Modern psychiatry was first introduced to mainland China around 1900 by Western missionaries. By 1949 the field had developed gradually as a result of contact with Western psychiatry and especially its American practitioners. This paper analyses the role played by key individuals and events in this process in the years prior to 1949. It argues that modern psychiatry was introduced to China through a process of cultural adaptation in which the USA served as a bridge for German thought.
Preparation and Thermal Properties of Polypropylene Foils Filled with Talc or Boron Nitride Microparticles

The preparation and thermal properties of polypropylene foils, filled with ceramic microparticles, talc or boron nitride, are described. A slow, linear increase of thermal conductivity with volume percent of filler up to 30 vol % is detected. Reduction of the foil thickness bellow 200 micrometers leads to a significant increase of thermal conductivity. Specific thermal capacities of foils are temperature dependent, they decrease with filler incorporation.
BLUElink> Development of Operational Oceanography and Servicing in Australia

The Bureau of Meteorology is scheduled in 2007 to expand its oceanographic services for the Australian community to include operational mesoscale ocean forecasts. The past decade has seen the rapid development of a near real-time global ocean observing system which includes both insitu and satellite instrumentation. The spatial coverage and frequency of observations has provided the capacity for developing ocean prediction systems. Operational oceanography is a significant investment both in terms of human and computational resources, which is being actively pursued in public centres throughout the world. BLUElink is a joint initiative of the Bureau of Meteorology, Commonwealth Scientific and Industrial Research Organisation and the Royal Australian Navy to develop this capability for Australia’s regional and territorial waters. Numerical ocean prediction is a computationally intensive task with the prototype system requiring resources comparable with numerical weather prediction and similarly takes full advantage of the very latest in high performance computing. In addition, the volume of observational, model and analysis data has demanded a comprehensive data management system. Effective information technology solutions are essential for managing, maintaining and servicing this new capacity to fulfil the needs of the Australian community.