Miracle-dz/UniFAR-FTUs huggingface dataset:
Focused Reflection Reminiscence Group for Elders: Implementation and Evaluation

The majority of elders have at least one or more chronic conditions. Functional decline coupled with increased dependence can make elders more vulnerable to negative emotions. Reminiscence can be useful in maintaining a healthy psychological adaptation in the later years of life. This study examined the effectiveness of a specific type of reminiscence in reducing negative emotions in 32 elders residing in retirement communities. This type of reminiscence, called focused reflection, was organized into six weekly, 2-hour group sessions, each with a specific theme. Paired t tests suggested that the focused reflection program reduced symptoms of depression and anxiety but not those reflecting agitation. Overall, the participants gave high ratings to the program. Health care providers should develop focused reflection reminiscence programs to enhance the psychological well-being of elders. Further testing of the focused reflection in larger groups of elders is recommended.
Synaptopodin Regulates Spine Plasticity: Mediation by Calcium Stores

The role of synaptopodin (SP), an actin-binding protein residing in dendritic spines, in synaptic plasticity was studied in dissociated cultures of hippocampus taken from control and SP knock-out (SPKO) mice. Unlike controls, SPKO cultures were unable to express changes in network activity or morphological plasticity after intense activation of their NMDA receptors. SPKO neurons were transfected with SP-GFP, such that the only SP resident in these neurons is the fluorescent species. The localization and intensity of the transfected SP were similar to that of the native one. Because less than half of the spines in the transfected neurons contained SP, comparisons were made between SP-containing (SP(+)) and SP lacking (SP(−)) spines in the same dendritic segments. Synaptic plasticity was induced either in the entire network by facilitation of the activation of the NMDA receptor, or specifically by local flash photolysis of caged glutamate. After activation, spines that were endowed with SP puncta were much more likely to expand than SP(−) spines. The spine expansion was suppressed by thapsigargin, which disables calcium stores. The mechanism through which SP may promote plasticity is indicated by the observations that STIM-1, the sensor of calcium concentration in stores, and Orai-1, the calcium-induced calcium entry channel, are colocalized with SP, in the same dendritic spines. The structural basis of SP is likely to be the spine apparatus, found in control but not in SPKO cells. These results indicate that SP has an essential, calcium store-related role in regulating synaptic plasticity in cultured hippocampal neurons.
Functional Characteristics of the Flying Squirrel's Cecal Microbiota under a Leaf-Based Diet, Based on Multiple Meta-Omic Profiling

Mammalian herbivores rely on microbial activities in an expanded gut chamber to convert plant biomass into absorbable nutrients. Distinct from ruminants, small herbivores typically have a simple stomach but an enlarged cecum to harbor symbiotic microbes; however, knowledge of this specialized gut structure and characteristics of its microbial contents is limited. Here, we used leaf-eating flying squirrels as a model to explore functional characteristics of the cecal microbiota adapted to a high-fiber, toxin-rich diet. Specifically, environmental conditions across gut regions were evaluated by measuring mass, pH, feed particle size, and metabolomes. Then, parallel metagenomes and metatranscriptomes were used to detect microbial functions corresponding to the cecal environment. Based on metabolomic profiles, >600 phytochemical compounds were detected, although many were present only in the foregut and probably degraded or transformed by gut microbes in the hindgut. Based on metagenomic (DNA) and metatranscriptomic (RNA) profiles, taxonomic compositions of the cecal microbiota were dominated by bacteria of the Firmicutes taxa; they contained major gene functions related to degradation and fermentation of leaf-derived compounds. Based on functional compositions, genes related to multidrug exporters were rich in microbial genomes, whereas genes involved in nutrient importers were rich in microbial transcriptomes. In addition, genes encoding chemotaxis-associated components and glycoside hydrolases specific for plant beta-glycosidic linkages were abundant in both DNA and RNA. This exploratory study provides findings which may help to form molecular-based hypotheses regarding functional contributions of symbiotic gut microbiota in small herbivores with folivorous dietary habits.
Pragmatic Discourse and Gender Inequality in China

Using courtroom dialogues in actual court trials in China as data, this article analyzes an emerging “pragmatic discourse,” deployed by judges to assist but the same time to constrain divorcing women. Through questions, statements, rebuttals, and other interactional devices, Chinese judges define the premises that underpin the law’s understanding of gender equality and women’s welfare. By looking at how discourses are deployed by judges and litigants, we link micro linguistic practices to more general social forces and processes. Despite their honest effort to protect women’s rights, Chinese judges often inadvertently reinforce and reproduce the patriarchal norm. The data demonstrate how the hegemonic patriarchal order reasserts itself in an institutional forum that is meant to promote gender equality. The interaction of the discourses also highlights the tensions in Chinese society and displays the effect of changing social environment on the legal operation.
An Alternative Approach to Analyze Ipsative Data. Revisiting Experiential Learning Theory

The ritualistic use of statistical models regardless of the type of data actually available is a common practice across disciplines which we dare to call type zero error. Statistical models involve a series of assumptions whose existence is often neglected altogether, this is specially the case with ipsative data. This paper illustrates the consequences of this ritualistic practice within Kolb's Experiential Learning Theory (ELT) operationalized through its Learning Style Inventory (KLSI). We show how using a well-known methodology in other disciplines—compositional data analysis (CODA) and log ratio transformations—KLSI data can be properly analyzed. In addition, the method has theoretical implications: a third dimension of the KLSI is unveiled providing room for future research. This third dimension describes an individual's relative preference for learning by prehension rather than by transformation. Using a sample of international MBA students, we relate this dimension with another self-assessment instrument, the Philosophical Orientation Questionnaire (POQ), and with an observer-assessed instrument, the Emotional and Social Competency Inventory (ESCI-U). Both show plausible statistical relationships. An intellectual operating philosophy (IOP) is linked to a preference for prehension, whereas a pragmatic operating philosophy (POP) is linked to transformation. Self-management and social awareness competencies are linked to a learning preference for transforming knowledge, whereas relationship management and cognitive competencies are more related to approaching learning by prehension.
Women's Perception of Life Following Breast Reduction: A Phenomenological Study

Problem Little is known about the lived experiences of women following breast reduction surgery. Many studies addressed surgical technique or physical symptoms, but few looked at quality-of-life issues. Aims The aim of this qualitative study was to understand subjective issues of life after breast reduction surgery. Increased knowledge about this group of women may direct or guide nursing practice. Procedure A convenience sample of 9 English-speaking women aged 23—53 years were recruited during their follow-up visit. Patients were asked, “What is life like following your breast reduction? ” Analysis A phenomenological approach was used to provide a rigorous, critical, and systematic study of the phenomenon. Analysis involved looking for themes. Giorgi's method guided the analysis. Findings Themes that emerged were improved physical health, increased self-esteem, self-confidence, and enhanced body image. In addition, preoperative expectations of the postoperative period varied from those of actual recovery, creating issues for some women. Significance Following breast reduction surgery, women experienced enhanced quality of life and improved physical symptoms.
Maximal sharing in the Lambda calculus with letrec

Increasing sharing in programs is desirable to compactify the code, and to avoid duplication of reduction work at run-time, thereby speeding up execution. We show how a maximal degree of sharing can be obtained for programs expressed as terms in the lambda calculus with letrec. We introduce a notion of 'maximal compactness' for λletrec-terms among all terms with the same infinite unfolding. Instead of defined purely syntactically, this notion is based on a graph semantics. λletrec-terms are interpreted as first-order term graphs so that unfolding equivalence between terms is preserved and reflected through bisimilarity of the term graph interpretations. Compactness of the term graphs can then be compared via functional bisimulation. We describe practical and efficient methods for the following two problems: transforming a λletrec-term into a maximally compact form; and deciding whether two λletrec-terms are unfolding-equivalent. The transformation of a λletrec-terms L into maximally compact form L0 proceeds in three steps: (i) translate L into its term graph G = [[L]] ; (ii) compute the maximally shared form of G as its bisimulation collapse G0 ; (iii) read back a λletrec-term L0 from the term graph G0 with the property [[L0]] = G0. Then L0 represents a maximally shared term graph, and it has the same unfolding as L. The procedure for deciding whether two given λletrec-terms L1 and L2 are unfolding-equivalent computes their term graph interpretations [[L1]] and [[L2]], and checks whether these are bisimilar. For illustration, we also provide a readily usable implementation.
Resonance Based Target Recognition Using Ultrawideband Polarimetric Signatures

Automated target recognition based on resonances embedded in the ultrawideband transient signatures has been of significant research interest throughout the years. In most studies, targets are usually illuminated and measured using a linear polarized basis. This could lead to an incorrect result for target recognition as some resonant modes may not be well excited at that particular incident aspect and polarization state. In this communication, the possibility of using a full-polarimetric ultrawideband target signature is investigated. Target recognition of some simple wire targets using the extinction pulse technique demonstrate that it would be easier to fully excite all of the important resonances using a circular polarization basis with due consideration of the co- and cross-polarized target signatures.
A Structural Analysis of the Qualitative Networks Regulating the Cell Cycle and Apoptosis

This paper proposes an integration and modular organization of the complex regulatory networks involved in the mammalian cell cycle, apoptosis, and related intracellular signaling cascades. A common node linking the cell cycle and apoptosis permits the possibility of coordinate control between the initiation of these two cellular processes. From this node, pathways emanate that lead to the activation of cyclin-dependent kinases (in the cell cycle) and caspases (in apoptosis). Computer simulations are carried out to demonstrate that the proposed network architecture and certain module-module interactions can account for the experimentally observed sequence of cellular events (quiescence, cell cycle, and apoptosis) as the transcriptional activities of E2F-1 and c-Myc are increased. Despite the lack of quantitative kinetic data on most of the pathways, it is demonstrated that there can be meaningful conclusions regarding system stability that arise from the topology of the network. It is shown that only cycles in the network graph determine stability. Thus, several positive and negative feedback loops are identified from a literature review of the major pathways involved in the initiation of the cell cycle and of apoptosis.
Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH.

Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on its diagnostic value in adults. We conducted a single-center retrospective study of 78 consecutive adults who had sIL-2r measured for suspected HLH. Serum sIL-2r levels were measured by enzyme-linked immunosorbent assay (adult reference range, 241-846 U/mL). There were 38 patients with HLH and 40 with a non-HLH diagnosis (such as sepsis, liver disease, histiocyte disorders, autoimmune disease, leukemia, or lymphoma). The receiver operating characteristic curve demonstrated that sIL-2r is a good to excellent diagnostic test for adult HLH, with an area under the curve (AUC) of 0.90 (95% confidence interval, 0.83-0.97) compared with AUC 0.78 (95% confidence interval, 0.67-0.88) for ferritin. The optimal threshold for sIL-2r was 2515 U/mL (sensitivity, 100%; specificity, 72.5%). Although there was a large indeterminate range for sIL-2r, a level of 2400 U/mL or less was helpful for ruling out HLH (sensitivity, 100%), and more than 10 000 U/mL was helpful for ruling in HLH (specificity, 93%). Higher mean sIL-2r levels were seen in malignancy-associated HLH (20 241 U/mL) compared with infection-associated HLH and macrophage activation syndrome (9720 and 5008 U/mL, respectively; P < .05). Levels above 10 000 U/mL were not associated with worse prognosis in patients with HLH. Serum sIL-2r is a sensitive test for diagnosis of adult HLH, but is not as specific as previously reported in children. Additional studies enriched with patients without HLH who have conditions associated with T-cell activation, such as lymphoma and autoimmune lymphoproliferative syndrome, are needed.
Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

A majority of human genes use alternative cleavage and polyadenylation to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs). Here, Lianoglou et al. develop a sequencing method, 3′-seq, to measure 3′ UTR isoform expression across diverse human tissues and isogenic transformation systems. The analyses reveal that during transformation and differentiation, single-UTR genes typically change their mRNA abundance levels, while multi-UTR genes change 3′ UTR isoform ratios to achieve tissue specificity. This study offers surprising new insights into how cell type-specific gene expression is achieved.
Convergence culture in the creative industries

• This article maps the emerging practices in media professions like journalism, advertising, marketing communications and public relations in adapting to a new global environment, characterized by an increasingly participatory media culture. Among creatives and brand managers in ad agencies `interactive advertising' is at the center of the contemporary buzz. Marketers in the cultural industries brainstorm about the potential of upstream marketing, while in public relations the opportunities of two-way symmetrical communication are explored. Editors of news publications increasingly jump on the `citizen journalism' bandwagon. All these trends are part of the same phenomenon: a convergence of the cultures of media production and consumption. In this essay, these developments are discussed in terms of their potential impact on consensual assumptions about the nature of media work, seen through the lens of the combination of individual creativity and mass production, also known as creative industries. •
Expectancy-Value Relationships of Shame Reactions and Shame Resiliency.

This study investigated expectancy-value predictors for experiencing shame from test feedback and the possible consequences of these shame reactions. Those who experienced shame included a broader range of students than previously thought, including some high achievers who had high self-perceptions of competence. Main expectancy-value predictors of shame were lower self-efficacy ratings and higher intrinsic as well as extrinsic goal orientations. Also, although having important future goals for which the course had instrumental value was not predictive of inducing shame, such goals appeared to exert influence on whether a person would be resilient from a shame reaction with increased motivation, motivated behavior, and higher academic exam scores. If students believe they have the capabilities and are committed to a clear future goal for which the course grade or course information is relevant, then a shame reaction may be a warning signal that current actions are not in line with future goal attainment. For these students, a personal evaluation of goal commitment may result in increased motivated behavior.
Access to education in sub‐Saharan Africa: patterns, problems and possibilities

The numbers of children with access to basic education in sub‐Saharan Africa have increased substantially over the last two decades but many still remain out of school. Some fail to enrol at all, especially in fragile states, and many more start school but do not complete the basic cycle. Education for All (EFA) and the Millennium Development Goals (MDGs) have generated commitments to improve greatly access to education. This paper first develops an expanded vision of access. Second, it analyses participation by grade and identifies five different country patterns. Third, changes in enrolments over time are explored which show that in some countries progress has been very uneven and that overall expansion may conceal large increases in lower grades and little change in completion rates. Fourth, data on age in grade are used to show that many children are overage and this may have consequences for attempts to lower dropout and improve completion rates. Fifth, participation by household income remains very uneven, especially at secondary level and wealth remains the most powerful determinant of progression to higher educational levels. Sixth, there has been good progress on some other sources of inequality, e.g. gender disparities, but much remains to be achieved, especially in fragile states. Concluding remarks draw out some policy related conclusions for future EFA priorities.
Optimistic Bias, Sexual Assault, and Fear

ABSTRACT A survey of 431 adults documents optimistic bias regarding people's perceived risk of sexual victimization. The findings extend optimistic bias to crime victimization and contribute to the literature by considering a motivational factor, fear, as a predictor of optimistic bias. The study also yielded significant relationships between optimistic bias and demographic variables, including age, gender, and family structure.
Canine leptospirosis infections - clinical signs and outcome with different suspected Leptospira serogroups (42 cases).

OBJECTIVES The aim of the study was to investigate the presence of serum antibodies to different Leptospira serogroups in dogs with a clinical diagnosis of leptospirosis in southern Germany and to compare seroreactivity to different serogroups with history, clinical signs, laboratory findings and survival rate. METHODS In this study, the data of 42 dogs with the diagnosis of leptospirosis were evaluated retrospectively. Dogs were presented to the Small Animal Medicine Teaching Hospital (Medizinische Kleintierklinik) of the Ludwig Maximilians University Munich, Germany, between 1990 to 2003. RESULTS Reactivity to the serogroup grippotyphosa (13/42) was most frequently present, followed by reactivity to the serogroup saxkoebing (10/42). There was no difference in the clinical picture and the laboratory changes between dogs whose sera were reactive to different serogroups. CLINICAL SIGNIFICANCE Most of the dogs with leptospirosis in southern Germany had sera reacting to serogroups other than icterohaemorrhagiae and canicola, which are contained in the vaccine. Thus, currently available vaccines in Europe do not protect against the most common Leptospira organisms associated with clinical disease.
Planning, urban design and the night-time city

The planning system was constrained by a neo-liberalist insistence on land-use planning in the 1980s and early 1990s, thereby providing the institutional framework for deregulation of the numbers, capacities and types of licensed premises in town and city centres. This had a direct impact on levels of crime, violence and anti-social behaviour. Criminologists have criticized planners for their complicity in this process. The article argues that entertainment uses have been marginal to the social and ecological preoccupations of the planning profession. It suggests that the reintroduction of spatial planning by the New Labour government has allowed planners to reassert social and environmental objectives into their development plans and potentially to introduce a greater degree of regulatory control. The article examines the changes to the planning system and its complex relation to licensing. Finally, it questions whether this new opportunity for planners to intervene will be realized in the current economic downturn.
The experimental study of cultural transmission: A pilot study on when and who people copy

Abstract : Culture influences behavior, and the way cultures change over time profoundly affects the way people's behavior changes. Cultural evolution -- the change in the content of a given culture over time -- is based on individual choices, whether it is what music people choose to listen to, whether people choose to adopt the latest technology or whether they absorb the tenets of violent fundamentalism. Unfortunately, scientists chronically lack evidence on how human psychological biases affect cultural evolution. In this research we have attempted to address this problem by experimentally probing the conditions under which people are more likely to turn to social information over their own existing knowledge or beliefs, and when they do, which kind of individuals are more likely to be chosen as information sources. Given the huge impact even a single, fanatically motivated individual can have in the era of modern terrorism, understanding the factors that lead individuals to be influenced toward and away from certain behavior patterns is essential strategic knowledge in any effort to reduce the influence of violent fundamentalism. This research provides an opportunity to begin creating essential foundational knowledge for the understanding of cultural change built by the choices of many individuals.
Grateful recounting enhances subjective well-being: The importance of grateful processing

We used a randomized controlled trial to test the effectiveness of a gratitude 3-blessings treatment for enhancing subjective well-being. Although several experimental studies have investigated gratitude interventions, many of these have used inadequate control conditions, and currently we know little about how gratitude treatments work. In this study, subjects were randomly assigned to one of three daily 1-week treatments: memory placebo, pride 3-blessings, or gratitude 3-blessings. The gratitude 3-blessings treatment significantly outperformed the comparison treatments in enhancing well-being. Moreover, the well-being of those in the gratitude treatment continued to climb after the treatment phase, similar to the findings of Seligman, Steen, Park, and Peterson (2005). We also found that the gratitude treatment enhanced the accessibility of positive memories compared to the comparison treatments. Our results suggest that exercises like the gratitude 3-blessings treatment may train cognitive biases that are salubrious to subjective well-being.