Miracle-dz/UniFAR-FTUs huggingface dataset:
Formations of feelings, constellations of things

This essay revisits Raymond Williams’s notion of ‘structures of feeling’ with the intention of clarifying what Williams meant by ‘feelings’, and of exploring the concept’s possible range and reach within the study of culture. It recovers the initial anthropological context for the phrase by reconnecting it to the work of Ruth Benedict and Gregory Bateson. It goes on to suggest that while the analysis of ‘structures of feeling’ has been deployed primarily in studies of literary and filmic culture it might be usefully extended towards the study of more ubiquitous forms of material culture such as clothing, housing, food, furnishings and other material practices of daily living. Indeed it might be one way of explaining how formations of feeling are disseminated, how they suture us to the social world and how feelings are embedded in the accoutrements of domestic, habitual life. The essay argues that by joining together a socially phenomenological interest in the world of things, accompanied by an attention to historically specific moods and atmospheres, ‘structures of feelings’ can direct analyses towards important mundane cultural phenomena.
HOW EFFECTIVE ARE MULTIPLE POPULATIONS IN GENETIC PROGRAMMING

The use of multiple populations in Genetic Programming is an area that is just beginning to be investigated. To date a number of conflicting reports have been generated with respect to the effectiveness of multiple populations in GP. We report here that these conflicting reports may be due a problem-dependent nature found in GP that has not been reported in GAs. This paper will review: what both multiple populations and speed-up mean in the areas of GA/GP, some conflicting results that have been reported in the GP literature on whether multiple populations gives speed-up to GP problems, and offer an answer as to why different GP problems show different kinds of speed-up when using multiple populations.
Dominant Negative Effectors of Heparin Affin Regulatory Peptide (HARP) Angiogenic and Transforming Activities*

Heparin affin regulatory peptide (HARP) is an heparin-binding growth factor, highly expressed in several primary human tumors and considered as a rate-limiting angiogenic factor in tumor growth, invasion, and metastasis. Implication of this protein in carcinogenesis is linked to its mitogenic, angiogenic, and transforming activities. Recently, we have demonstrated that the C-terminal residues 111–136 of HARP are required for its mitogenic and transforming activities (Bernard-Pierrot, I., Delbe, J., Caruelle, D., Barritault, D., Courty, J., and Milhiet, P. E. (2001) J. Biol. Chem. 276, 12228–12234). In this paper, HARP deleted of its last 26 amino acids was shown to act as a dominant negative effector for its mitogenic, angiogenic, transforming, and tumor-formation activities by heterodimerizing with the wild type protein. Similarly, the synthetic corresponding peptide P111–136 displayed in vitro inhibition of wild type HARP activities, but in this case, the inhibition was mainly explained by the competition of the peptide with HARP for the binding to the extracellular domain of the high affinity ALK receptor.
Contribution of different dispersal sources to the metabolic response of lake bacterioplankton following a salinity change

Dispersal can modify how bacterial community composition (BCC) changes in response to environmental perturbations, yet knowledge about the functional consequences of dispersal is limited. Here we hypothesized that changes in bacterial community production in response to a salinity disturbance depend on the possibility to recruit cells from different dispersal sources. To investigate this, we conducted an in situ mesocosm experiment where bacterial communities of an oligotrophic lake were exposed to different salinities (0, 18, 36 psu) for 2 weeks and subjected to dispersal of cells originating from sediments, air (mesocosms open to air deposition), both or none. BCC was determined using 454 pyrosequencing of the 16S rRNA gene and bacterial production was measured by 3 H leucine uptake. Bacterial production differed significantly among salinity treatments and dispersal treatments, being highest at high salinity. These changes were associated with changes in BCC and it was found that the identity of the main functional contributors differed at different salinities. Our results further showed that after a salinity perturbation, the response of bacterial communities depended on the recruitment of taxa, including marine representatives (e.g., Alphaproteobacteria Loktanella, Erythrobacter and the Gammaproteobacterium Rheiheimera) from dispersal sources, in which atmospheric deposition appeared to play a major role.
Aspergillus species identification in the clinical setting

Multiple recent studies have demonstrated the limited utility of morphological methods used singly for species identification of clinically relevant aspergilli. It is being increasingly recognised that comparative sequence based methods used in conjunction with traditional phenotype based methods can offer better resolution of species within this genus. Recognising the growing role of molecular methods in species recognition, the recently convened international working group meeting entitled “Aspergillus Systematics in the Genomic Era” has proposed several recommendations that will be useful in such endeavors. Specific recommendations of this working group include the use of the ITS regions for inter section level identification and the β-tubulin locus for identification of individual species within the various Aspergillus sections.
Paracetamol-induced fixed drug eruption at an unusual site.

BACKGROUND Paracetamol (acetaminophen) is a widely used analgesic/antipyretic drug for which hypersensitivity reactions appear to be increasingly frequent. OBJECTIVE We report the case of a woman who experienced several delayed selective reactions induced by paracetamol: fixed drug eruptions (FDEs) with typical features but an unusual distribution (hard palate and a maculopapular rash. METHODS Skin tests: prick, intradermal and patch tests as well as a single-blind oral challenge test (OCT) were performed. RESULTS Skin tests were negative. The OCT was necessary to confirm the diagnosis. Interestingly, the challenge test elicited an FDE-type lesion instead of a maculopapular rash. CONCLUSIONS Our findings could reflect 2 different clinical patterns of delayed allergic reactions, or, more probably, the initial phase of a unique clinical entity that was stopped by the corticosteroids prescribed during the challenge. However, we were unable to confirm these hypotheses. The uncommon anatomical site of the lesions (hard palate) is noteworthy. Some relevant patents are also summarized in this paper.
The seroprevalence of leptospirosis in Anatolian buffaloes in Turkey

SUMMARY Leptospirosis is a commonly zoonosis in many rainy countries caused by Leptospira interrogans. The aim of the study was to determine the leptospirosis seroprevalence using microagglutination test for the first time in Anatolian buffaloes. Blood serum samples were collected from 93 buffaloes stemming from 6 different farms located in different provinces of the Anatolia region. The overall leptospirosis seroprevalence was 32.26% and similar infection frequencies were recorded in males and females as well as in young animals (0-2 years old) and adults (> 2 year old). Only 3 serovars were identified among positive buffaloes, the hardjo-hardjoprajitma strain being largely predominant (found in 66.67% of positive sera) whereas the grippotyphosa and icterohaemorrhagiae serovars were evidenced in 9 and 1 cases respectively. As these serovars are also identified in humans, these results show that Anatolian buffaloes as cattle in Turkey may contribute to the man contamination.
Early categorization abilities in young children with Williams syndrome

The present study investigated whether 2- to 6-year-old children with Williams syndrome can form new object categories based on either visual or verbal information alone. Children were presented with six triads of objects. In each triad, two objects either shared visual properties, or were given the same name. Following the presentation of each triad, categorization based on the shared visual or verbal property was evaluated through object manipulation. While the children categorized the objects according to visual cues, they failed to use the verbal cues. These results contrast with previous research showing that typically developing toddlers, who were much younger than the children with Williams syndrome and much less advanced in their vocabulary development, could perform both types of categorization. The present study hence supports the claim that vocabulary acquisition in Williams syndrome develops atypically.
Are Inmates With Military Backgrounds “Army Strong?”

We use data from the Survey of Inmates in State and Federal Correctional Facilities 2004 to examine the relationship between prior military service and misbehavior for a nationally representative sample of incarcerated inmates. Our regression analyses, based on 18,185 respondents across 326 prisons, suggest that inmates with military backgrounds tend to fare better than others across 12 negative prison outcomes. In contrast, we do not find much support for the argument—implied by violentization and other theories—that inmates with military backgrounds fare worse than others, with the exception of high levels of post-traumatic stress disorder (PTSD) and violent victimization. Supplementary analyses also show conditional patterns based on exposure to combat as well as honorable versus dishonorable discharge.
The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

Background—Endothelial lipase is a phospholipase with activity against high-density lipoprotein. Although a small number of mutations in LIPG have been described, the role of LIPG in protection against atherosclerosis is unclear. Methods and Results—We identified 8 loss-of-function (LOF) mutations in LIPG in individuals with high-density lipoprotein cholesterol. Functional analysis confirmed that most rare mutations abolish lipase activity in vitro, indicating complete LOF, whereas 2 more common mutations N396S and R476W reduce activity by ≈50%, indicating partial LOF and implying ≈50% and ≈75% remaining endothelial lipase function in heterozygous complete LOF and partial LOF mutation carriers, respectively. complete LOF mutation carriers had significantly higher plasma high-density lipoprotein cholesterol levels compared with partial LOF mutation carriers. Apolipoprotein B-depleted serum from complete LOF carriers showed significantly enhanced cholesterol efflux acceptor capacity, whereas only trends were observed in partial LOF carriers. Carriers of LIPG mutations exhibited trends toward reduced coronary artery disease in 4 independent cohorts (meta-analysis odds ratio, 0.7; P=0.04). Conclusions—Our data suggest that the impact of LIPG mutations is directly related to their effect on endothelial lipase function and support that antagonism of endothelial lipase function improves cardioprotection.
AFM, STM and Ellipsometry Characterization of a Monolayer of Azurin Molecules Self-Assembled on a Gold Surface in Air

th , 2005 Posted: May 5 th , 2005 Abstract Abstract We use several techniques to characterize the monolayer formed in air by the electron transfer protein, azurin, self-assembled on a gold substrate in a stable way. Tapping Mode Atomic Force Microscopy and Scanning Tunnelling Microscopy scans reveal the presence of individual molecules highly packed and stably bound to gold. The height of the single molecules, as determined by Atomic Force Microscopy is consistent with the thickness of the protein monolayer as measured with spectroscopic ellipsometry. Scanning Tunnelling Microscopy, operating in constant current mode, is able to image single molecules with a lateral size in agreement with the crystallographic dimension. Sweeps of bias voltage in tunnelling conditions point out a good electric contact of the single protein molecules with some rectifying behaviour.
Management of Articular Cartilage Defects of the Knee

Abstract Articular cartilage injuries of the knee present a difficult clinical dilemma and their treatment is controversial. Hyaline articular cartilage is an avascular, low-friction, and wear-resistant weightbearing surface that has limited capacity for self-repair. The optimal treatment for cartilage lesions has yet to be established. Various treatment methods are employed to reestablish a stable cartilage surface, including microfracture, autologous and allograft osteochondral transplantation, autologous chondrocyte implantation, matrix-associated chondrocyte implantation, and scaffold-assisted methods. Treatment algorithms help to guide physicians' decision making in the care of these injuries. In this article, results from outcomes studies as well as prospective randomized clinical trials comparing treatment methods are reviewed, and current practice guidelines are summarized.
Burnout among nurses

In this study, an investigation focussing on the relationship between stresses of person-helping professionals and their so-called burnout syndromes was conducted. Nine-hundred seventy nurses working at 10 different hospitals in Kyoto prefecture participated to this investigation.The Maslach Burnout Inventory (MBI; Maslach & Jackson, 1981), translated and revised for personhelping professionals in Japan, was used to measure the degree of burnout. As a result of factor analysis, three dimensions-emotional exhaustion, depersonalization, reduced personal acoomplishment-were extracted. Multiple regression analyses were conducted to examine the relationship between stresses and burnout. Several stresses related significantly to the three dimensions of burnout. Further, the relationship between personal characteristics and burnout, and the effect of social support on burnout were confirmed. These findings suggest that stresses induce burnout and that both personal characteristics and social supports play a significant role in the processes.
The Importance of Safe Patient Handling to Create a Culture of Safety: An Evidential Review

Manual patient handling has been linked to musculoskeletal disorders (MSDs) in healthcare workers. It can expose the musculoskeletal (MS) system of nurses and other healthcare workers to stress, and may put patients at risk for injury, pain and negative health outcomes. Creating a culture of safety around minimising manual patient handling is therefore thought to have a positive impact in diminishing the scope of this problem. Patient mobility is also an important clinical issue, and safe patient handling (SPH) and mobility technology can be used to promote mobilisation, to improve patient independence and quality of life. There is evidence to suggest that multifactor interventions based on a risk assessment programme have the most likely chance of success in reducing risk factors associated with patient handling activities. The introduction of a structured SPH programme that pairs training with ergonomic intervention and mechanical aid use is now believed to be the most effective workplace intervention to prevent injuries relating to manual patient handling. The aim of this review is to investigate available evidence for the effectiveness of SPH programmes from the perspectives of healthcare worker safety, patient safety and cost. It is hoped that this will provide a broad view on the current state, significance and future potential of such programmes. Further, we consider what is missing from the available evidence, and how we can improve our understanding of SPH programme effectiveness in the healthcare setting.
Simulation of unmanned air vehicle flocking

Flocking style behavior is commonplace in nature. It provides a number of benefits for groups of creatures on the move at little cost. Unmanned air vehicles are becoming increasingly popular for a variety of applications and are often used in groups. Manually controlling many UAVs at high densities can be difficult. The simple, efficient and safe nature of flocking as an automated flight control method, potentially make it an ideal solution for maneuvering groups of UAVs. The paper investigates the implementation of a real-time graphical simulation of flocking UAVs. Of particular interest is simulating simplified realistic aircraft dynamics in real-time and allowing flocking rule parameters and weightings to be interactively adjusted in order to investigate the effects they have on flocking behavior. The paper describes work carried out for an MSc. research project, which is now being utilized for the authors Ph.D research.
Adolescent Romantic Relationship Partners, Characteristics, Satisfaction, and Commitment

According to Self-Determination Theory (SDT), individuals are motivated by three psychological needs: relatedness, competence, and autonomy. These needs can be met or challenged through the characteristics of one's romantic partner and relationships, leading to healthy outcomes such as satisfaction. In this study, SDT was applied to assess the extent to which underlying needs are important to middle adolescent romantic relationship desires, experiences, and outcomes. This study had two key aims: to assess the importance of developmentally-salient partner characteristics and to assess the adequacy with which partner characteristics and relationship characteristics account for the relationship outcomes of satisfaction and commitment among middle adolescents. Survey data were collected from 235 adolescents (M_age= 15.66; SD = 1.08) who were currently or recently in romantic relationships. A new measure of developmentally-salient partner characteristics was created for this study and functioned largely as expected, though partner intimacy and social status emerged as a single factor rather than as distinct factors. Adolescent relationships were generally healthy as indicated through relatively high ratings of partner personality (which includes expression of intimacy and social status), partner autonomy support, relationship intimacy, relationship passion, and low ratings of relationship abuse. As hypothesized, partner characteristics that more directly serve underlying needs (i.e., personality, identity support, autonomy support) were predictive of relationship outcomes, while those that indirectly serve needs (i.e., attractiveness) or do not serve needs (i.e. financial status) were not. Further, relationship characteristics of intimacy, passion, and abuse were related to, yet distinct from, partner characteristics and explained a significant proportion of additional variance in outcomes. Taken together, the extent to which partners and relationships can serve underlying needs was important to well-being as indicated through the outcomes of relationship satisfaction and commitment. The relations among partner and relationship characteristics and between these and outcomes add credence to the assertion that romantic relationships can be healthy contexts for adolescent development.
Validation of the Five Minute Speech Sample in Measuring Expressed Emotion*

The relationship of the Five Minute Speech Sample (FMSS) to the Camberwell Family Interview and its coding system were evaluated. The Camberwell Family Interview and the FMSS were administered to twenty-three relatives of patients diagnosed with schizophrenia. Overall, the results supported the utility of the FMSS and its coding system as a brief screening device for measuring expressed emotion.
Weak Shareholder Rights: A Product Market Rationale

In product markets where customers care about firm survival, strong shareholder power, by affecting the likelihood that the firm will be acquired, can have detrimental implications on firm performance. We use a framework where firms choose their level of shareholder rights after comparing the costs of acquisition exposure, i.e, the loss of customers, with the synergistic benefits of an acquisition to generate two testable implications. First, we show that it is optimal to have weak shareholder rights in competitive markets. Second, we show that the link between weak shareholder rights and competition is stronger when the number of firms in the industry is lower. Using data on shareholder rights in the corporate charter, we find that indeed firms have stronger shareholder rights in concentrated industries and that this link is stronger in industries with fewer firms. Additionally, the link between concentration and shareholder rights is stronger in industries characterized by long-term customer relationships. We also document that weak shareholder rights are associated with worse performance only in non-competitive industries. We then discuss the implications of this framework for the design of various governance mechanisms. In conclusion, the paper provides a rationale for why shareholders themselves might not want strong shareholder rights.
Female Reproductive Factors and Differentiated Thyroid Cancer

Differentiated thyroid cancer (DTC) is markedly more common in women than men, the highest female-to-male ratio being recorded during the reproductive period. This evidence has led to the suggestion that female hormonal and reproductive factors may account for the observed DTC gender disparity. This review focuses on current evidence on the risk of DTC in conjunction with major female reproductive factors, including the impact of pregnancy on DTC occurrence and progression/recurrence. Overall, studies exploring the link between the risk of DTC and menstrual and menopausal factors, oral contraceptives and/or hormone replacement therapy, showed these associations, if any, to be generally weak. Nonetheless, there is some evidence that higher levels of exposure to estrogens during reproductive years may confer an increased risk of DTC. As far as pregnancy is concerned, it is unclear whether a potential association between parity and risk of DTC actually exists, and whether it is enhanced in the short-term following delivery. A possible role for pregnancy-related factors in DTC progression has been recently suggested by some reports, the results of which are consistent with a worse outcome in the short-term of women diagnosed with DTC during gestation compared to non-pregnant control patients. Also, some progression of disease has been described in women with structural evidence of disease prior to pregnancy. However, there seems to be no impact from pregnancy in DTC-related death or overall survival. Several in vitro and animal studies have evaluated the influence of estrogens (E) and estrogen receptors (ERs) on thyroid cell proliferation. Presently available data are indicative of a role of E and ERs in thyroid cancer growth, although considerable discrepancies in respect to ER expression patterns in thyroid cancer tissues actually exist. Further studies providing more direct evidence on the possible role of E and of placental hormones and growth factors on thyroid growth may expand our knowledge on the mechanisms beyond the gender disparity of proliferative thyroid diseases.
A Common Progenitor for Retinal Astrocytes and Oligodendrocytes

Developing neural tissue undergoes a period of neurogenesis followed by a period of gliogenesis. The lineage relationships among glial cell types have not been defined for most areas of the nervous system. Here we use retroviruses to label clones of glial cells in the chick retina. We found that almost every clone had both astrocytes and oligodendrocytes. In addition, we discovered a novel glial cell type, with features intermediate between those of astrocytes and oligodendrocytes, which we have named the diacyte. Diacytes also share a progenitor cell with both astrocytes and oligodendrocytes.