Miracle-dz/UniFAR-FTUs huggingface dataset:
MOTIVASI UNTUK MELAKUKAN PEMERIKSAAN PAYUDARA SENDIRI (SADARI) SEBELUM DAN SESUDAH PENDIDIKAN KESEHATAN TENTANG KANKER PAYUDARA PADA WANITA USIA SUBUR

ABSTRACT Background: breast cancer is a cancer that often occurs in women and BSE attempt to do for the early detection of breast cancer. Objective: to determine differences in motivation to perform breast self-examination (BSE) before and after health education about breast cancer in fertile women in the village Sukolilo district Pati Methods: The type of pre-experimental research design with pre-post test in one group. The population is 309 souls fertile women. Sample of 47 respondents. Test statistic by using wilcoxon test. Result: motivation to perform breast-self examination (BSE) before health education among women of fertile women are mostly in the category of lacking motivation, namely a total of 32 respondents (68,1%), whereas after a given health education mostly in the category of quite as many as 31 respondents (66,0%). Conclusions: there are differences in motivation to perform breast self-examination (BSE) before and after health education in fertile women Wuwur Pati Village. Keywords: motivation, Breast Cancer, Breast Self Examination (BSE) ABSTRAK Latar Belakang : kanker payudara merupakan kanker yang sering terjadi pada perempuan dan SADARI merupakan upaya yang dapat dilakukan untuk deteksi dini kanker payudara. Tujuan : Mengetahui perbedaan motivasi untuk melakukan pemeriksaan payudara sendiri (SADARI) sebelum dan sesudah pendidikan kesehatan tentang kanker payudara pada wanita usia subur di Desa Wuwur Kabupaten Pati. Metode : jenis penelitian Pra-Eksperimental dengan rancangan Pra-Post Test Dalam Satu Kelompok (One Group Pretest-Postest Design). Populasi dalam penelitian ini adalah 309 jiwa wanita usia subur. Sample sebanyak 47 responden. Uji statistic dengan menggunakan uji wilcoxon. Hasil penelitian : motivasi untuk melakukan pemeriksaan payudara sendiri (SADARI) sebelum pendidikan kesehatan pada wanita usia subur sebagian besar dalam kategori motivasi kurang yaitu sebanyak 32 responden (68,1%), sedangkan setelah diberikan pendidikan kesehatan sebagian besar dalam kategori cukup yaitu sebanyak 31 responden (66,0). Kesimpulan : ada perbedaan motivasi untuk melakukan pemeriksaan payudara sendiri (SADARI) sebelum dan sesudah pendidikan kesehatan pada wanita usia subur di Desa Wuwur RW 1 Kabupaten Pati. Kata kunci: motivasi, kanker payudara, pemeriksaan payudara sendiri,
The Future of News: Presentation, Storytelling and Use of Web Technologies on Traditional and Startup News Websites

This explorative thesis research was conducted because there has been little to no literature researching the specific topic of presentation, storytelling and use of web technologies on online news websites in the last decade. At the same time a recent wave of new (startup) natively digital news websites show interesting differences with the online efforts of traditional news organizations and are able to somehow realize growth in a declining industry. In this thesis the topic is researched by performing both a content analysis of three traditional and startup news websites, and conducting interviews at traditional newspaper organization De Volkskrant and its parent organization de Persgroep. This thesis research proves that it is indeed useful for researchers to reconsider researching the topic, by finding extensive differences in the presentation, storytelling and use of web technologies between those two types of organizations and exploring several possible strategies, motivations and circumstances that could explain these differences.
Up-Regulated Expression and Aberrant DNA Methylation of LEP and SH3PXD2A in Pre-Eclampsia

The primary mechanism underlying pre-eclampsia (PE) remains one of the most burning problems in the obstetrics and gynecology. In this study, we performed an expression profiling screen and detected 1312 genes that were differentially expressed (p<0.05 and fold change >1.5) in PE placentas, including LEP and SH3PXD2A. After validating the microarray results, we conducted the quantitative methylation analysis of LEP and SH3PXD2A in preeclamptic (n = 16) versus normal placentas (n = 16). Our results showed that many CpG sites close to the transcriptional start site (TSS) of LEP gene were hypomethylated in placentas from pregnancies with PE compared with those of in controls, including the TSS position (p = 0.001), the binding sites of Sp1 (p = 1.57×10−4), LP1 (p = 0.023) and CEBPα (p = 0.031). Luciferase reporter analysis confirmed the aberrant methylation of LEP promoter and CEBPα co-transfection had a role in the regulation of gene expression. Our results indicated the aberrant LEP promoter methylation was involved in the development of PE. We did not find a significant methylation differences between groups in the promoter region of SH3PXD2A, however, a CGI region in the gene body (CGI34) presented a higher methylation in preeclamptic placentas (p = 1.57×10−4), which might promote the efficiency of gene transcription. We speculated that SH3PXD2A may take part in the pathogenesis of PE through its role in the regulation of trophoblast cell invasion in the period of placenta formation.
Wechsler Çocuklar İçin Zeka Ölçeği Geliştirilmiş Formunun Doğrulayıcı Faktör Analizi : Normal Zihinsel Gelişim Gösteren Çocukların Oluşturduğu Bir Örneklem

Wechsler Intelligence Scale for Children-Revised (WISC-R) is one of scales commonly used in intellectual assessment in our country for many years. There hasn’t been any research aimed at testing construct validity of this scale after its norm study was conducted in 1995. The aim of this study is to test construct validity of the scale by performing confirmatory factor analysis for WISC-R scores of children who has intellectually normal development. The sample of the research consisted of 932 children whose General Intelligence Quantity (IQ) ranged between 80-120. In the research, WISC-R’s IQ’s and scores of 10 main subtests were used. In the research, mean age of the children is 10.97 ± 2.78 and General IQ is 101.93 ± 9.88. One-factor model (g factor) and two-factor model (verbal and performance) was tested and it was found that fit index values of two-factor model [χ2 (32, N = 932) = 132.05, χ2/sd = 4.12, GFI = . 97, AGFI = . 95, CFI = . 88, RMSEA = . 05] was better than one-factor model [χ2 (33, N = 932) = 141.10, χ2/sd = 4.27, GFI = . 97, AGFI = . 95, CFI = . 86, RMSEA = . 06]. The research findings suggested that the two-factor model existed in structure of the WISC-R presented by Wechsler was supported in this sample. Given WISC-R is commonly used in both clinical and educational fields; it is considered that two-factor model can give more useful information about individuals with normal intellectual development than one-factor model.
Correlated Detection of sub-mHz Gravitational Waves by Two Optical-Fiber Interferometers

Results from two optical-fiber gravitational-wave interferometric detectors are reported. The detector design is very small, cheap and simple to build and operate. Using two detectors has permitted various tests of the design principles as well as demonstrating the first simultaneous detection of correlated gravitational waves from detectors spatially separated by 1.1 km. The frequency spectrum of the detected gravitational waves is sub-mHz with a strain spectral index 1.4 0.1. As well as characterising the wave effects the detectors also show, from data collected over some 80 days in the latter part of 2007, the dominant earth rotation effect and the earth orbit effect. The detectors operate by exploiting light speed anisotropy in optical-fibers. The data confirms previous observations of light speed anisotropy, earth rotation and orbit effects, and gravitational waves.
Government Purchases Over the Business Cycle: the Role of Heterogeneity and Wealth Bias in Political Decision Making

This paper sets up and computes a stochastic neoclassical growth model where agents face uninsurable idiosyncratic labor income risk and heterogenous discount factors. Households value government purchases which are financed by income taxes. The government cannot commit to future streams of government purchases. We thus study the Markov perfect equilibria of such an economy. We also introduce a wealth bias into the political aggregation process. When exposed to standard aggregate productivity shocks, we show that such a model can explain three important features of government purchases in the data: government purchases are mildly procyclical, their dynamic correlation with one-year lagged output is higher than the corresponding contemporaneous correlation, and they are the most persistent component of aggregate demand. We also show that a representative agent model, models with insufficient wealth inequality and models with no wealth bias cannot explain these features of the data.
An Introduction to Nonlinear Dimensionality Reduction by Maximum Variance Unfolding

Many problems in AI are simplified by clever representations of sensory or symbolic input. How to discover such representations automatically, from large amounts of unlabeled data, remains a fundamental challenge. The goal of statistical methods for dimensionality reduction is to detect and discover low dimensional structure in high dimensional data. In this paper, we review a recently proposed algorithm-- maximum, variance unfolding--for learning faithful low dimensional representations of high dimensional data. The algorithm relies on modem tools in convex optimization that are proving increasingly useful in many areas of machine learning.
Measurement of Technology Behaviors: A Look at Texting Scales

The measurement of technology behaviors occurs in everyday interactions with websites and smart devices, and can be applied to customize interfaces to improve users’ experiences as well as increasing revenues via targeted ads. This is possible because technology behaviors can reflect underlying personal and psychological characteristics about users that can be utilized to deliver custom-tailored content to each user. Texting is a one technology behavior that has been shown to be associated with a variety of psychological variables, including personality, depression, and anxiety, and has been shown to relate to socio-developmental differences among different age groups. Thus, the measurement of texting behaviors could have potential applications for researchers and practitioners. The present study examined a new scale to measure texting behavior: the Texting Behaviors Index (TBX; Schroeder & Sims, 2017), alongside two scales that measure problematic aspects of mobile phone use (Merlo, Stone, & Bibbey, 2013) and motivations for texting (Reid & Reid, 2007). Results indicate that measures from the TBX converge with the other texting scales, and support the TBX’s usefulness as a measure of texting behavior.
Categorical perception of English /r/ and /l/ by Japanese bilinguals

ABSTRACT Categorical perception of a synthetic /r/-/l/ continuum was investigated with Japanese bilinguals at two levels of English language experience. The inexperienced Japanese group, referred to as Not-experienced, had had little or no previous training in English conversation. The Experienced Japanese group had had intensive training in English conversation by native American-English speakers. The tasks used were absolute identification, AXB discrimination, and oddity discrimination. Results showed classic Categorical perception by an American-English control group. The Not-experienced Japanese showed near-chance performance on all tasks, with performance no better for stimuli that straddled the /r/-/l/ boundary than for stimuli that fell in either category. The Experienced Japanese group, however, perceived /r/ and /l/ categorically. Their identification performance did not differ from the American-English controls, but their overall performance levels on the discrimination tests were somewhat lower than for the Americans. We conclude that native Japanese adults learning English as a second language are capable of Categorical perception of /r/ and /l/. Implications for perceptual training of phonemic contrasts are discussed.
Long-Term Followup Comparing Two Treatment Dosing Strategies of 125I Plaque Radiotherapy in the Management of Small/Medium Posterior Uveal Melanoma

Objective. To investigate the efficacy of two different dosing strategies of radioactive iodine-125 (125I) in the management of small- and medium-sized posterior uveal melanoma. Patients and Methods. The medical records of consecutive patients with choroidal melanomas between 1.5 and 5.0 mm in apical height treated initially with 125I plaque radiotherapy were reviewed. Patients were treated with one of the following two treatment dosing strategies: (1) 85 Gy to the apical height of the tumor (group 1) or (2) 85 Gy to a prescription point of 5.0 mm (group 2). Results. Of 95 patients, 55 patients were treated to the apical height of the tumor, and 40 were treated to a prescription point of 5.0 mm. Comparative analysis of the incidence rates of specific complications between the two groups demonstrates that group 2 had a significantly higher incidence of radiation retinopathy, radiation optic neuropathy, and/or visually significant cataract formation than group 1 (P = 0.028). Conclusion. Treatment of choroidal melanomas less than 5 mm in apical height with 125I brachytherapy to the true apical height is equally effective when compared to treatment with 85 Gy to 5.0 mm. Treatment to the apical height of the tumor may result in lower incidence of radiation-related complications.
Prion-like spreading of pathological α-synuclein in brain

α-Synuclein is the major component of filamentous inclusions that constitute the defining characteristic of neurodegenerative α-synucleinopathies. However, the molecular mechanisms underlying α-synuclein accumulation and spread are unclear. Here we show that intracerebral injections of sarkosyl-insoluble α-synuclein from brains of patients with dementia with Lewy bodies induced hyperphosphorylated α-synuclein pathology in wild-type mice. Furthermore, injection of fibrils of recombinant human and mouse α-synuclein efficiently induced similar α-synuclein pathologies in wild-type mice. C57BL/6J mice injected with α-synuclein fibrils developed abundant Lewy body/Lewy neurite-like pathology, whereas mice injected with soluble α-synuclein did not. Immunoblot analysis demonstrated that endogenous mouse α-synuclein started to accumulate 3 months after inoculation, while injected human α-synuclein fibrils disappeared in about a week. These results indicate that α-synuclein fibrils have prion-like properties and inoculation into wild-type brain induces α-synuclein pathology in vivo. This is a new mouse model of sporadic α-synucleinopathy and should be useful for elucidating progression mechanisms and evaluating disease-modifying therapy.
When cyberbullies meet gamers: what do young adults think?

Abstract Background Cyberbullying is connected with online gaming in complex ways. Although cyberbullying can occur while people play games, it is also the case that gaming may have the potential to address cyberbullying and bullying problems. Purpose This study examines young adults’ beliefs and experiences related to cyberbullying and gaming. Sample The participants were 357 students who were enrolled in a university on the East coast of the United States of America. Design and methods A survey instrument, consisting of mainly Likert-type scale questions, was developed, refined and analysed quantitatively, in order to investigate young adults’ views and opinions. Results More than half of the participants reported that they were directly involved in cyberbullying, either as a victim or a harasser, while playing online games. Close to 70% of participants observed cyberbullying incidents in gaming contexts. Action games, role-playing games and sports games were perceived as the main genres of game where cyberbullying may take place. In addition, a vast majority of the young adults reported that they were willing to play anti-cyberbullying games. A series of essential game elements were identified, based on young adults’ preferred gaming styles. A correlational analysis suggested some associations between participants’ beliefs and actions. The limitations of the study and further development of the survey instrument are discussed, in terms of its potential for further research. Conclusions The high percentage of students involved in cyberbullying while gaming suggests that online gaming may be an environment where cyberbullying proliferates. Equally, though, the finding that the majority of the participants in this study would consider playing anti-cyberbullying games indicates the potential contribution of games for addressing cyberbullying issues. It is hoped that the specific gaming elements that were identified by the participants will help with the effective design of intervention and prevention anti-bullying programmes that involve games.
Mild cognitive impairment represents early-stage Alzheimer disease.

BACKGROUND Mild cognitive impairment (MCI) is considered to be a transitional stage between aging and Alzheimer disease (AD). OBJECTIVE To determine whether MCI represents early-stage AD by examining its natural history and neuropathologic basis. DESIGN A prospective clinical and psychometric study of community-living elderly volunteers, both nondemented and minimally cognitively impaired, followed up for up to 9.5 years. Neuropathologic examinations were performed on participants who had undergone autopsy. SETTING An AD research center. PARTICIPANTS All participants enrolled between July 1990 and June 1997 with Clinical Dementia Rating (CDR) scores of 0 (cognitively healthy; n = 177; mean age, 78.9 years) or 0.5 (equivalent to MCI; n = 277; mean age, 76.9 years). Based on the degree of clinical confidence that MCI represented dementia of the Alzheimer type (DAT), 3 subgroups of individuals with CDR scores of 0.5 were identified: CDR 0.5/DAT, CDR 0.5/incipient DAT, and CDR 0.5/uncertain dementia. MAIN OUTCOME MEASURE Progression to the stage of CDR 1, which characterizes mild definite DAT. RESULTS Survival analysis showed that 100% of CDR 0.5/DAT participants progressed to greater dementia severity over a 9.5-year period. At 5 years, rates of progression to a score of CDR 1 (or greater) for DAT were 60.5% (95% confidence interval [CI], 50.2%-70.8%) for the CDR 0.5/DAT group, 35.7% (95% CI, 21.0%-50.3%) for the CDR 0.5/incipient DAT group, 19.9% (95% CI, 8.0%-31.8%) for the CDR 0.5/uncertain dementia group, and 6.8% (95% CI, 2.2%-11.3%) for CDR 0/controls. Progression to greater dementia severity correlated with degree of cognitive impairment at baseline. Twenty-four of the 25 participants with scores of CDR 0.5 had a neuropathologic dementing disorder, which was AD in 21 (84%). CONCLUSIONS Individuals currently characterized as having MCI progress steadily to greater stages of dementia severity at rates dependent on the level of cognitive impairment at entry and they almost always have the neuropathologic features of AD. We conclude that MCI generally represents early-stage AD.
Automated thermal image segmentation of knee rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the systemic autoimmune disorders characterized by chronic inflammation in multiple joints eventually leading to bone erosion and cartilage damage. The main symptoms are (i) morning stiffness (ii) joint swelling (iii) inflammation (iv) neovascularisation (v) cell infiltration and (vi) synovial hyperplasia. Early diagnosis helps in the effective treatment of the disease, however, in the early stages there may not be apparent joint swelling and often present negative radiographs. The common diagnostic methods include Magnetic Resonance (MR) imaging and clinical and health assessment questionnaire. However, MRI is quite expensive; hence, there is a need for cost-effective and safer technique for the diagnosis of RA. Therefore, this study focuses on the application of non-invasive, radiation-free, cost economic technique namely thermography in the diagnosis of early stage RA. The main aim of this paper is to compare various segmentation algorithms, namely manual, colour and k-means image segmentation and to find out the best suitable segmentation algorithm for thermal images. The hot spot region is extracted using three different image segmentation algorithms and compared with the normal thermograph to determine the effective segmentation algorithm in the detection of early stage RA.
Entropy Fluctuations in Brane Inflation Models

We study the development of entropy fluctuations in brane inflation in a warped throat, including the brane-antibrane tachyon as the waterfall field. We find that there is a period at the end of inflation during which the entropy mode associated with the tachyon field increases exponentially. In turn, the induced entropy seeds a contribution to the curvature fluctuation on cosmological scales which grows rapidly and could exceed the primordial curvature perturbation. We identify parameter values for which in the absence of back-reaction the induced curvature fluctuations are larger than the primordial adiabatic ones. In the specific model we study, however, back-reaction limits the growth of the entropy fluctuations. We discuss situations in which back-reaction effects are less constraining. The lesson of our investigation is that the study of the development of entropy fluctuations at the end of the period of inflation can lead to constraints on models of brane inflation and suggests that the curvaton mechanism may contribute significantly to the spectrum of cosmological perturbations.
Enhancing Security in Correlated Channel With Maximal Ratio Combining Diversity

In this correspondence, we consider a confidential communication through slow non-selective correlated Rayleigh fading channel, where a single antenna transmitter communicates at a pre-decided constant rate with a legitimate receiver in the presence of an eavesdropper. Both the legitimate receiver and eavesdropper are equipped with multiple antennas and employ maximal ratio combining (MRC) reception scheme. With the presence of channel diversity, we find the closed-form expressions for the probability of non-zero secrecy capacity and the outage probability of secrecy capacity in terms of channel parameters such as correlation coefficient and the ratio of main and eavesdropper channel gains that will be called average channel gain ratio (CGR). The analysis of secure outage performance with the MRC diversity scheme tells how the channel diversity enhances the secrecy capacity. We quantify the effect of antenna correlation on the probability of positive secrecy capacity and the secure outage probability. We also investigate how the target secrecy rate influences the effect of antenna correlation on the secure outage probability. Moreover, as a result of obtaining the closed-form expressions for the probability of positive secrecy capacity and the outage probability, it is insightful to see how the channel parameters affect the secure outage performance of the correlated channels.
An explicit solution for an optimal stopping/optimal control problem which models an asset sale.

In this article we study an optimal stopping/optimal control problem which models the decision facing a risk-averse agent over when to sell an asset. The market is incomplete so that the asset exposure cannot be hedged. In addition to the decision over when to sell, the agent has to choose a control strategy which corresponds to a feasible wealth process. We formulate this problem as one involving the choice of a stopping time and a martingale. We conjecture the form of the solution and verify that the candidate solution is equal to the value function. The interesting features of the solution are that it is available in a very explicit form, that for some parameter values the optimal strategy is more sophisticated than might originally be expected, and that although the setup is based on continuous diffusions, the optimal martingale may involve a jump process. One interpretation of the solution is that it is optimal for the risk-averse agent to gamble.