Miracle-dz/UniFAR-FTUs huggingface dataset:
Testing Moderating Effects for the Causal Structure Model of Self-Action- Outcome (SAO Model).

This study focuses on developing the Self-Action-Outcome (SAO) model and testing the moderating effects based on gender and academic performance. The SAO model examined the relationship between self-esteem, job-search intensity and career decision-making self-efficacy among graduating students. The instruments used to develop this model were, the Rosenberg Self-Esteem Scale, Job-Search Intensity Scale, and Career DecisionMaking Self-Efficacy Scale. Participants were recruited using a cluster sampling procedure. Data were collected using a self-reported questionnaire. Data collected from 678 graduating students were tested with confirmatory factor analysis to obtain three best-fit measurement models from the three latent variables. The results showed that the overall fit of the SAO model was adequate with CFI = . 977, TLI = . 971 and RMSEA = . 048. The statistics indicate that the parameters were free from offending estimates, ranging from . 52 to . 90. The moderators‟ variables such as gender and academic performance did not moderate the hypothesized SAO model means that the hypothesized SAO model is a good model among graduating students. Implications of the findings for social work practice such as guidance counsellor, research, theory, policy and education were also discussed.
Antecedents of Emotional Intelligence: An Empirical Study.

This study examined the relationships between emotional intelligence, locus of control, and mental boundaries. Three hundred and eighty-two county employees were sampled using a cross-sectional survey design. The results indicated internal locus of control and thin mental boundaries are positively related to emotional intelligence. A hierarchical regression revealed that internal locus of control and thin mental boundaries together explained 18% of the variance in emotional intelligence for this population. Implications and future research directions are discussed.
Individuation: Inner Work

The work of individuation proceeds in two movements, an analytic and a synthetic one. These are not sequential—first one, then the other—but rather take place in a rhythm specific to each individuation process. The analytic movement results in separation and differentiation; the synthetic movement builds up the transcendent function. Out of this process emerges an identity based on conscious and unconscious, personal and cultural (as well as archetypal) images and contents. Jungian analysis works in both directions through the analysis of identity and identifications, of transference contents and dynamics, of complexes and cultural assumptions as well as through the synthesis of emergent aspects of the self as they manifest in dreams, active imagination, and archetypal transference. The individuation process is lifelong and does not begin with entry into analysis or end with the termination of analysis.
Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

Purpose: Most treatments for patients with metastatic melanoma have a low rate of complete regression and thus overall survival in these patients is poor. We investigated the ability of adoptive cell transfer utilizing autologous tumor-infiltrating lymphocytes (TIL) to mediate durable complete regressions in heavily pretreated patients with metastatic melanoma. Experimental Design: Ninety-three patients with measurable metastatic melanoma were treated with the adoptive transfer of autologous TILs administered in conjunction with interleukin-2 following a lymphodepleting preparative regimen on three sequential clinical trials. Ninety-five percent of these patients had progressive disease following a prior systemic treatment. Median potential follow-up was 62 months. Results: Objective response rates by Response Evaluation Criteria in Solid Tumors (RECIST) in the 3 trials using lymphodepleting preparative regimens (chemotherapy alone or with 2 or 12 Gy irradiation) were 49%, 52%, and 72%, respectively. Twenty of the 93 patients (22%) achieved a complete tumor regression, and 19 have ongoing complete regressions beyond 3 years. The actuarial 3- and 5-year survival rates for the entire group were 36% and 29%, respectively, but for the 20 complete responders were 100% and 93%. The likelihood of achieving a complete response was similar regardless of prior therapy. Factors associated with objective response included longer telomeres of the infused cells, the number of CD8+CD27+ cells infused, and the persistence of the infused cells in the circulation at 1 month (all P2 < 0.001). Conclusions: Cell transfer therapy with autologous TILs can mediate durable complete responses in patients with metastatic melanoma and has similar efficacy irrespective of prior treatment. Clin Cancer Res; 17(13); 4550–7. ©2011 AACR.
The relationship between periodontal disease and preterm low birthweight: clinical and microbiological results.

BACKGROUND AND OBJECTIVE Findings on the effect of periodontal disease on preterm low birthweight are inconclusive. The objective of this study was to compare periodontal clinical measures and the levels and proportions of 39 bacterial species in subgingival biofilm samples in puerperal women with preterm low birthweight and nonpreterm low birthweight. MATERIAL AND METHODS A case-control study with 116 postpartum women over 30 years of age was conducted. Four case groups of subjects with preterm and/or low birthweight [preterm (n = 40), low birthweight (n = 35), preterm and/or low birthweight (n = 50) and preterm and low birthweight (n = 25)] were compared with normal nonpreterm low-birthweight controls (n = 66). Periodontal clinical parameters of dental plaque, calculus, bleeding on probing, periodontal pocket depth and clinical attachment level were recorded. Covariates included socio-demographic and anthropometric characteristics, smoking, alcohol consumption, obstetric history, prenatal care and diseases during pregnancy. Two subgingival biofilm samples per women were analyzed for 39 bacterial species using a checkerboard DNA-DNA hybridization technique. RESULTS The mean periodontal pocket depth was significantly higher in nonpreterm low-birthweight controls than in subjects in the preterm low birthweight, preterm and/or low birthweight, and preterm and low-birthweight groups. Clinical attachment level measures were not different between all pairs of cases and control groups. Groups did not differ with respect to the mean proportions of different microbial complexes. The mean counts of Treponema socranskii were lower in all case groups compared with the control group. CONCLUSION Maternal periodontal microbiota and clinical characteristics of periodontal disease were not associated with having preterm low-birthweight babies.
PENGEMBANGAN POSDAYA (POS PEMBERDAYAAN KELUARGA) UPAYA PEMBERDAYAAN MASYARAKAT LINGKAR KAMPUS (Development of Family Empowerment Program for the Communities Empowerment Surrounding the Campus)

Posdaya sebagai model pemberdayaan masyarakat di Indonesia telah bergulir sejak 2006. Dalam rangka pengembangan masyarakat di lingkar kampus IPB telah dilakukan upaya pemberdayaan masyarakat melalui Posdaya, namun belum mencakup seluruh desa binaan. Kajian ini merupakan implementasi pengembangan Posdaya, sosialisasi gerakan untuk lingkungan sehat dan penyuluhan untuk pengelolaan sampah. Pemilihan lokasi kajian dilakukan secara purposif dengan mempertimbangkan bahwa Kelurahan Situgede terletak di sekitar kampus IPB dan belum pernah dikembangkan Posdaya di wilayah tersebut. Berdasarkan hasil kajian yang dilakukan terhadap para tokoh masyarakat dan para kader Posdaya dapat diketahui bahwa pengetahuan masyarakat tentang Posdaya relatif baik dan mereka sudah memahami apa dan bagaimana tentang Posdaya. Namun masyarakat pada umumnya belum sepenuhnya mendukung karena realisasi dalam bentuk yang kongkrit tentang program dan dampak yang dikembangkan oleh Posdaya belum terwujud secara nyata. Faktor penting dalam pelaksanaan kegiatan Geulis Plus di Kelurahan Situgede, Kecamatan Bogor Barat, Kota Bogor ini adalah aspek keteladanan dari Tim Inti sebagai penggerak sekaligus pelaksana. Peserta pelatihan untuk pengelolaan sampah di tingkat rumah tangga akan lebih efektif jika melibatkan ibu-ibu rumah tangga, karena pada umumnya merekalah yang mengurusi sampah rumah tangga setiap harinya. Kata kunci : Pos pemberdyaan keluarga, POSDAYA, pemberdayaan masyarakat.
Molecular Determinants of CaV2.1 Channel Regulation by Calcium-binding Protein-1*

Background: Regulation of calcium channels by calcium-sensor proteins mediates short term synaptic plasticity. Results: Calcium-binding protein-1 (CaBP1) inhibits calcium channels through its N terminus and second EF-hand, which is inactive in calcium binding. Conclusion: Specific domains of CaBP1 are responsible for differential regulation, including an EF-hand inactive in calcium binding. Significance: These results reveal the molecular code used by calcium-sensor proteins to differentially regulate short term synaptic plasticity. Presynaptic CaV2.1 channels, which conduct P/Q-type Ca2+ currents, initiate synaptic transmission at most synapses in the central nervous system. Regulation of CaV2.1 channels by CaM contributes significantly to short term facilitation and rapid depression of synaptic transmission. Short term synaptic plasticity is diverse in form and function at different synapses, yet CaM is ubiquitously expressed. Differential regulation of CaV2.1 channels by CaM-like Ca2+ sensor (CaS) proteins differentially affects short term synaptic facilitation and rapid synaptic depression in transfected sympathetic neuron synapses. Here, we define the molecular determinants for differential regulation of CaV2.1 channels by the CaS protein calcium-binding protein-1 (CaBP1) by analysis of chimeras in which the unique structural domains of CaBP1 are inserted into CaM. Our results show that the N-terminal domain, including its myristoylation site, and the second EF-hand, which is inactive in Ca2+ binding, are the key molecular determinants of differential regulation of CaV2.1 channels by CaBP1. These findings give insight into the molecular code by which CaS proteins differentially regulate CaV2.1 channel function and provide diversity of form and function of short term synaptic plasticity.
MODELING CONTROL OF RABIES OUTBREAKS IN RED FOX POPULATIONS TO EVALUATE CULLING, VACCINATION, AND VACCINATION COMBINED WITH FERTILITY CONTROL

A predictive model of spread and control of rabies in red fox (Vulpes vulpes) populations was used to evaluate efficacy of culling, oral vaccination, and oral vaccination and fertility control (V+FC) as rabies control strategies. In addition, effects of season, fox population density, and a delay in starting control were modeled. At fox densities of 0.5 fox families/km2 or greater, a single oral vaccination campaign with bait uptake rates of less than 50% resulted in ineffective rabies control. An uptake rate of at least 80% was required to give a better than 80% chance of eliminating rabies. Vaccination was least effective at controlling rabies if applied 1 or 2 mo before the foxes gave birth. Seasonal timing of poison or V+FC had little effect on efficacy, which was always more successful than the oral vaccination alone. The longer the delay between the simulated start of the rabies infection and the application of a single vaccination campaign, the less successful was the control, particularly at the higher fox densities tested. At a fox density of 0.25 families/km2, all the strategies were equally successful at eliminating rabies. At higher fox densities V+FC was slightly less successful than culling, whereas vaccination-only was considerably less successful. The sole use of vaccination is not considered a viable control method for areas with high fox densities. The model suggests that an area of culling centered on the disease focus, plus an outer ring of vaccine or V+FC, could be the best strategy to control a point-source wildlife rabies outbreak.
Effects of changing sea ice on marine mammals and subsistence hunters in northern Alaska from traditional knowledge interviews

Marine mammals are important sources of food for indigenous residents of northern Alaska. Changing sea ice patterns affect the animals themselves as well as access to them by hunters. Documenting the traditional knowledge of Iñupiaq and Yupik hunters concerning marine mammals and sea ice makes accessible a wide range of information relevant to understanding the ecosystem to which humans belong. We interviewed hunters in 11 coastal villages from the northern Bering Sea to the Beaufort Sea. Hunters reported extensive changes in sea ice and weather that have affected the timing of marine mammal migrations, their distribution and behaviour and the efficacy of certain hunting methods. Amidst these changes, however, hunters cited offsetting technological benefits, such as more powerful and fuel-efficient outboard engines. Other concerns included potential impacts to subsistence hunting from industrial activity such as shipping and oil and gas development. While hunters have been able to adjust to some changes, continued environmental changes and increased disturbance from human activity may further challenge their ability to acquire food in the future. There are indications, however, that innovation and flexibility provide sources of resilience.
Neurophysiological Manifestations of Phonological Processing: Latency Variation of a Negative ERP Component Timelocked to Phonological Mismatch

Two experiments examined phonological priming effects on reaction times, error rates, and event-related brain potential (ERP) measures in an auditory lexical decision task. In Experiment 1 related prime-target pairs rhymed, and in Experiment 2 they alliterated (i.e., shared the consonantal onset and vowel). Event-related potentials were recorded in a delayed response task. Reaction times and error rates were obtained both for the delayed and an immediate response task. The behavioral data of Experiment 1 provided evidence for phonological facilitation of word, but not of nonword decisions. The brain potentials were more negative to unrelated than to rhyming word-word pairs between 450 and 700 rnsec after target onset. This negative enhancement was not present for word-nonword pairs. Thus, the ERP results match the behavioral data. The behavioral data of Experiment 2 provided no evidence for phonological Facilitation. However, between 250 and 450 msec after target onset, i.e., considerably earlier than in Experiment 1, brain potentials were more negative for unrelated than for alliterating Word-word and word-nonword pairs. It is argued that the ERP effects in the two experiments could be modulations of the same underlying component, possibly the N400. The difference in the timing of the effects is likely to be due to the fact that the shared segments in related stimulus pairs appeared in different word positions in the two experiments.
eaf chlorophyll constraint on model simulated gross primary roductivity in agricultural systems

Leaf chlorophyll content (Chll) may serve as an observational proxy for the maximum rate of carboxylation (Vmax), which describes leaf photosynthetic capacity and represents the single most important control on modeled leaf photosynthesis within most Terrestrial Biosphere Models (TBMs). The parameterization of Vmax is associated with great uncertainty as it can vary significantly between plants and in response to changes in leaf nitrogen (N) availability, plant phenology and environmental conditions. Houborg et al. (2013) outlined a semi-mechanistic relationship between V25 max(Vmax normalized to 25 ◦C) and Chll based on inter-linkages between V25 max, Rubisco enzyme kinetics, N and Chll. Here, these relationships are parameterized for a wider range of important agricultural crops and embedded within the leaf photosynthesis-conductance scheme of the Community Land Model (CLM), bypassing the questionable use of temporally invariant and broadly defined plant functional type (PFT) specific V25 max values. In this study, the new Chll constrained version of CLM is refined with an updated parameterization scheme for specific application to soybean and maize. The benefit of using in-situ measured and satellite retrieved Chll for constraining model simulations of Gross Primary Productivity (GPP) is evaluated over fields in central Nebraska, U.S.A between 2001 and 2005. Landsat-based Chll time-series records derived from the Regularized Canopy Reflectance model (REGFLEC) are used as forcing to the CLM. Validation of simulated GPP against 15 site-years of flux tower observations demonstrate the utility of Chll as a model constraint, with the coefficient of efficiency increasing from 0.91 to 0.94 and from 0.87 to 0.91 for maize and soybean, respectively. Model performances particularly improve during the late reproductive and senescence stage, where the largest temporal variations in Chll (averaging 35–55 g cm−2 for maize and 20–35 g cm−2 for soybean) are observed. While prolonged periods of vegetation stress did not occur over the studied fields, given the usefulness of Chll as an indicator of plant health, enhanced GPP predictabilities should be expected in fields exposed to longer periods of moisture and nutrient stress. While the results support the use of Chll as an observational proxy for V25 max, future work needs to be directed towards improving the Chll retrieval accuracy from space observations and developing consistent and physically realistic modeling schemes that can be parameterized with acceptable accuracy over spatial and temporal domains.
Buffer and channel adaptive modulation for transmission over fading channels

We consider the problem of adaptive modulation for increasing the throughput of transmission over fading channels. In the model, packets arrive at a finite-length buffer according to a Poisson distribution and are mapped into M-ary quadrature amplitude modulated (MQAM) symbols for transmission over a correlated Rayleigh fading channel. We assume that buffer and channel state information are always available at the transmitter. Our objective is to vary the transmit power and the signal constellation size of the modulator according to both the buffer and channel states so that the system throughput is maximized under some average transmit power and bit error rate (BER) constraints. We formulate this optimization problem as a Markov decision process (MDP) and use dynamic programming techniques to obtain the solution. More importantly, we show that, under certain conditions, the optimal transmission rate increases when the channel gain decreases toward the outage threshold - the point below which communication is not possible. This is in contrast to the water-filling structure of the link adaptive policy that achieves capacity on fading channels.
Dynamic Aspects of Acute Mitral Regurgitation: Effects of Ventricular Volume, Pressure and Contractility on the Effective Regurgitant Orifice Area

The dynamics of acute mitral regurgitation were studied in six open-chest dogs in whom a portion of the anterior leaflet was excised. Phasic mitral and aortic flows were measured electromagnetically and left ventricular filling volume, regurgitant volume (RV) and forward stroke volume (SV) were calculated. The systolic pressure gradient (SPG) between the left ventricle (LV) and left atrium (LA) was obtained from highfidelity pressure transducers. The effective mitral regurgitant orifice area (MRA) was calculated from the hydraulic equation of Gorlin.Volume infusion resulted in significant increases in both left atrial and left ventricular pressures; thus, the SPG was unchanged and the increase in RV was due primarily to the increase in MRA. Angiotensin infused to raise arterial pressure resulted in greater increments in left ventricular than left atrial pressure, so that SPG rose significantly. The increase in RV was due to increases in both MRA and SPG. Norepinephrine infusion increased systolic left ventricular pressure and SPG, while left ventricular end-diastolic pressure and left atrial pressure diminished. Despite a significant increase in SPG, RV did not increase, due to a substantial decrease in MRA. Thus, angiotensin and volume infusion induced a substantial increase in regurgitation due to the increase in MRA, while augmentation of contractility after norepinephrine infusion resulted in a decrease in regurgitation through reduction of MRA. These findings support the clinical view that maintaining a small LV with sustained myocardial contractility will reduce mitral regurgitation. Alternatively, left ventricular dilatation can enhance mitral regurgitation by increasing the effective regurgitant orifice independent of SPG.
Everyday Life Cognitive Instability Predicts Simple Reaction Time Variability: Analysis of Reaction Time Distributions and Delta Plots

Summary The goal of this study is to understand the interface between subjectively assessed and objectively measured attention functioning. To this end, we assessed both self-report data using the Cognitive Failures Questionnaire (CFQ) and sustained-attention performance using a low-demand psychomotor vigilance task that required participants to respond to visual targets. Unlike previous studies, reliability of task performance was ensured, testing individuals twice within a retest interval of 1 week. Given that everyday life attentional lapse tendencies vary even in normal-population samples, we asked whether there is a relationship with laboratory performance, in general and as a consequence of time on task (TOT). As a result, low (versus high) CFQ scorers were somewhat different in their average response speed but became particularly prone to lapsing during the task period, as reflected in standard measures of response-speed variability as well as ex-Gaussian parameters of distributional skewness. In conclusion, we argue that persistence to sustained demand might be an important aspect of construct validity that must be evoked by a manipulation of TOT, which may be useful for the evaluation of questionnaires in ecologically valid situations. Copyright © 2015 John Wiley & Sons, Ltd.
Efficient Semiparametric Estimation of Short‐Term and Long‐Term Hazard Ratios with Right‐Censored Data

The proportional hazards assumption in the commonly used Cox model for censored failure time data is often violated in scientific studies. Yang and Prentice (2005) proposed a novel semiparametric two‐sample model that includes the proportional hazards model and the proportional odds model as sub‐models, and accommodates crossing survival curves. The model leaves the baseline hazard unspecified and the two model parameters can be interpreted as the short‐term and long‐term hazard ratios. Inference procedures were developed based on a pseudo score approach. Although extension to accommodate covariates was mentioned, no formal procedures have been provided or proved. Furthermore, the pseudo score approach may not be asymptotically efficient. We study the extension of the short‐term and long‐term hazard ratio model of Yang and Prentice (2005) to accommodate potentially time‐dependent covariates. We develop efficient likelihood‐based estimation and inference procedures. The nonparametric maximum likelihood estimators are shown to be consistent, asymptotically normal, and asymptotically efficient. Extensive simulation studies demonstrate that the proposed methods perform well in practical settings. The proposed method successfully captured the phenomenon of crossing hazards in a cancer clinical trial and identified a genetic marker with significant long‐term effect missed by using the proportional hazards model on age‐at‐onset of alcoholism in a genetic study.