Miracle-dz/UniFAR-FTUs huggingface dataset:
Dielectric rod waveguide components at sub-THz frequencies

Aalto University, P.O. Box 11000, FI-00076 Aalto www.aalto. fi Author Andrey Generalov Name of the doctoral dissertation Dielectric rod waveguide components at sub-THz frequencies Publisher School of Electrical Engineering Unit Department of Radio Science and Engineering Series Aalto University publication series DOCTORAL DISSERTATIONS 99/2015 Field of research Radio Engineering Manuscript submitted 13 May 2015 Date of the defence 7 August 2015 Permission to publish granted (date) 9 July 2015 Language English Monograph Article dissertation (summary + original articles)
Reliability in Theory and Practice

Quantitative measurement of software reliability remains an elusive goal. Simultaneously, there is an ever increasing critical dependency on software-based systems in the human infrastructure. There is a great deal of research in addition to well-intentioned methods and practices focused on improving the reliability of software-based systems. To date, most of which still only yields qualitative measurements except in very simple cases, e.g. a very few hundred lines of code. Probabilistic methods, such as reliability growth models, do offer a statistical inference for applications amenable to the methods. This talk will explore the meaning of software rcliahility in the context of safety, security, control, and quality attributes from an ultra-high assurance systems perspective, e.g. nuclear weapons. A systems level perspective will he taken related to the sources of defects (failure potential), including the “cross product” of software and hardware failure state spaces. The authors view of opportunities to improve the reliability of software-based will he presented.
Extended XML Tree Pattern Matching: Theories and Algorithms

As business and enterprises generate and exchange XML data more often, there is an increasing need for efficient processing of queries on XML data. Searching for the occurrences of a tree pattern query in an XML database is a core operation in XML query processing. Prior works demonstrate that holistic twig pattern matching algorithm is an efficient technique to answer an XML tree pattern with parent-child (P-C) and ancestor-descendant (A-D) relationships, as it can effectively control the size of intermediate results during query processing. However, XML query languages (e.g., XPath and XQuery) define more axes and functions such as negation function, order-based axis, and wildcards. In this paper, we research a large set of XML tree pattern, called extended XML tree pattern, which may include P-C, A-D relationships, negation functions, wildcards, and order restriction. We establish a theoretical framework about “matching cross” which demonstrates the intrinsic reason in the proof of optimality on holistic algorithms. Based on our theorems, we propose a set of novel algorithms to efficiently process three categories of extended XML tree patterns. A set of experimental results on both real-life and synthetic data sets demonstrate the effectiveness and efficiency of our proposed theories and algorithms.
Trends in Incidence and Outcome of Stroke in Perth, Western Australia During 1989 to 2001: The Perth Community Stroke Study

Background and Purpose— We studied temporal trends in major stroke outcomes in Perth, Western Australia (WA), comparing 3 12-month periods, roughly 5 years apart, between 1989 and 2001. Methods— The Perth Community Stroke Study (PCSS) used uniform definitions and procedures in a representative segment (approximately 143 000 people in the year 2000) of Perth, WA. Crude and age-standardized incidence and 28-day case fatality for stroke in the different study periods were compared using Poisson regression. We also undertook temporal comparisons of severity, risk factors, and management of stroke to define the basis for any changes in rates. Data are reported with 95% confidence intervals (CI). Results— There were 251, 213, and 183 first-ever strokes identified in the first, second, and third study periods, respectively, reflecting significant declines in stroke rates overall, for major age groups, and for both ischemic stroke and intracerebral hemorrhage. The decline in rates was greater in men than women. Compared with the 1989 to 1990 period, sex- and age-adjusted rates declined by 25% (95% CI 10% to 37%) in 1995 to 1996, and by 43% (95% CI 31% to 53%) in 2000 to 2001, corresponding to a 5.5% average annual decrease overall. There were correspondingly significant reductions in the frequencies of key risk factors among cases. However, early case fatality remained stable, both overall and for major pathological subtypes of stroke. Conclusions— These data confirm significant declines in the incidence of stroke on the western side of Australia, coincident with some improvement in the vascular risk profile of cases in the population. Decreasing risk rather than improving survival appears to be the main driver of falling mortality from stroke in this population.
On Neighbor Information Utilization in Distributed Receding Horizon Control for Consensus-Seeking

This paper investigates the issue on how to utilize neighbor information in the distributed receding horizon control (RHC)-based consensus problem for first-order multiagent systems. The distributed RHC-based consensus problem is first formulated in a general framework in terms of using neighbor information. Based on the framework, a sufficient condition on utilizing neighbor information to ensure consensus is developed for the finite horizon case. For the infinite horizon case, a necessary and sufficient condition is proposed, and the best way of using neighbor information to achieve fastest convergence rate is also presented. It is shown that: 1) the way of utilizing neighbor information plays an important role in reaching consensus; 2) the parameter that ensures consensus is related with the network topology; and 3) the best convergence rate in consensus can be attained if the neighbor information is appropriately utilized. Simulation studies verify the proposed theoretical results.
Reward Sensitivity of ACC as an Intermediate Phenotype between DRD4-521T and Substance Misuse

The development and expression of the midbrain dopamine system is determined in part by genetic factors that vary across individuals such that dopamine-related genes are partly responsible for addiction vulnerability. However, a complete account of how dopamine-related genes predispose individuals to drug addiction remains to be developed. Adopting an intermediate phenotype approach, we investigated whether reward-related electrophysiological activity of ACC—a cortical region said to utilize dopamine reward signals to learn the value of extended, context-specific sequences of goal-directed behaviors—mediates the influence of multiple dopamine-related functional polymorphisms over substance use. We used structural equation modeling to examine whether two related electrophysiological phenomena associated with the control and reinforcement learning functions of ACC—theta power and the reward positivity—mediated the relationship between the degree of substance misuse and genetic polymorphisms that regulate dopamine processing in frontal cortex. Substance use data were collected from 812 undergraduate students. One hundred ninety-six returned on a subsequent day to participate in an electrophysiological experiment and to provide saliva samples for DNA analysis. We found that these electrophysiological signals mediated a relationship between the DRD4-521T dopamine receptor genotype and substance misuse. Our results provide a theoretical framework that bridges the gap between genes and behavior in drug addiction and illustrate how future interventions might be individually tailored for specific genetic and neurocognitive profiles.
Clinical implications of variations in anti‐infliximab antibody levels in patients with inflammatory bowel disease

Background: The aim of the study was to investigate variations in anti‐infliximab (IFX) antibody (Ab) levels and clinical implications thereof in patients with inflammatory bowel disease (IBD). Methods: A retrospective, explorative, single‐center study of patients with IBD who developed anti‐IFX Ab and in whom anti‐IFX Ab were reassessed. Results: IFX was administered to 316 patients; anti‐IFX Ab was determined in 180 patients and detected in 83 (46%). During ongoing IFX maintenance therapy, anti‐IFX Ab disappeared at later reassessment in two‐thirds of patients with clinical response after median 4 (3–5) infusions. In contrast, anti‐IFX Ab persisted in all patients without clinical response. Anti‐IFX Ab appeared pharmacologically active, as IFX levels were high when anti‐IFX Ab disappeared (median 3.7 &mgr;g/mL, interquartile range [IQR] 2.8–5.5), while undetectable or low when anti‐IFX Ab persisted (median 0 &mgr;g/mL, IQR 0–0). In 56 patients, anti‐IFX Ab were assessed after IFX discontinuation. The proportion of patients with anti‐IFX Ab gradually declined over time, with a few patients having anti‐IFX Ab up to about 4 years after initial assessment. No variables were associated with anti‐IFX Ab disappearance in multivariate analysis. Conclusions: Discontinuation of IFX is advisable in patients with inadequate response and repeat positive anti‐IFX Ab measurements. Anti‐IFX Ab can persist for years after discontinuation, which could impact efficacy and safety at retreatment. Continued IFX treatment may, however, be considered in patients with clinical response and a single positive anti‐IFX Ab measurement, as anti‐IFX Ab disappears in two‐thirds of these during continued treatment. (Inflamm Bowel Dis 2012;)
PENERAPAN MODEL PEMBELAJARAN BIOLOGI BERBASIS READING – CONCEPT MAP –TEAMS GAMES TOURNAMENTS UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS DAN HASIL BELAJAR KOGNITIF SISWA KELAS X IPA 4 SMA LABORATORIUM UM

This research aims to enhance critical thinking skills and cognitive learning outcomes of students of class X IPA 4 SMA Laboratorium UM, through the aplication of Biology learning model based on Reading – Concept Map – Teams Games Tournaments . This research is a Classroom Action Research (CAR) which consisted of two cycles. Cycle I carried as many as eleven times of meetings and the cycle II carried as many as twelve times of meetings. The subjects of this research are the 31 of class X IPA 4 SMA Laboratorium UM, comprising 11 male students and 12 female students. The increased results of the students’s critical thinking abilities can be seen from the end of the cycle test as follows. The test results were analyzed using critical thinking skills assessment rubric adapted from Hart. The assessment is done on the basis of some musty among other truths answers given, the ability to provide the right answers and reasons and in accordance with the order of the sentences logically correct and proper language rules. Cognitive learning outcomes data obtained from the test results were analyzed using the answer key cognitive learning outcomes based on the truth of the material.This research shows that the results, critical thinking skills of students has increased from cycle I to cycle II. In the cycle I, the class average grade is 46,22; while in the cycle II, the class average grade is 72,71. As in critical thinking ability, the increased cognitive learning outcomes also can be known from the end of the cycle test results. In the cycle I, it has a class average grade of 49,74; while in cycle II, it has a class average grade of 69,69. Keywords: Biology Learning Model Based on Reading – Concept Map – Teams Games Tournaments , Critical Thinking Skills, Cognitive Learning Outcomes
Effects of Colistin Sulphate, Tigecycline, and Cefoperazone-Sulbactam on the Multi-Drug Resistant Acinetobacter baumannii Experimental Mouse Sepsis Model

Amac: Turkiye’de ve dunyada Acinetobacter enfeksiyonlarinin gorulme sikligi giderek artmaktadir. Acinetobacter turleri hizli direnc gelistirme yetenegi sayesinde ozellikle yenidogan ve cocukluk yas grubunda, immun sistemi baskilanmis hastalarda ve yogun bakim yatisi gerektiren hastalarda mortalite ve morbiditeye sebep olmaktadir. Karbapenem direnci gelisen Acinetobacter enfeksiyonlarinda tedavi secenekleri kisitlidir. Bu calismada karbapenem direncli Acinetobacter baumanii-calcaetecus complex susu ile olusturulan deneysel sepsis modelinde kolistin sulfat, tigesiklin ve sefoperazon-sulbaktam’in in vitro etkinliklerinin karsilastirilmasi planlandi. Gerec ve Yontemler: Calismaya her antibiyotik grubunda ve kontrol grubunda sekiz deney hayvani olacak sekilde 32 adet Wistar cinsi albino rat alindi. Siklofosfamid ile notropeni olusturulan ratlara Acinetobacter baumannii/calcoaceticus complex (107 koloni) inokulumu intraperitoneal olarak verildi. Tum tedavi gruplarinda ve kontrol grubunda 24. saatte kan kulturu ve 72. saatte akciger, karaciger ve bobrek orneklerinde ureme saptananlarda koloni sayimi yapildi. Bulgular: Tigesiklin tedavisi uygulanan grupta 24. saat kan kulturu uremesi kontrol grubuna gore dusuk olarak saptandi (p=0,01). Akciger orneklerinde kulturde ureme sikliginin tigesiklin (p<0,05), kolistin (p<0,05)ve sefoperazon-sulbaktam (p<0,05) gruplarinda kontrol grubuna gore istatistiksel olarak dusuk saptandi. Karaciger orneklerinde kulturde ureme sikliginin kolistin (p<0,05) ve sefoperazon-sulbaktam Abstract
Comparative Evaluation of Ketamine - Propofol, Fentanyl - Propofol and Butorphanol-Propofol on Haemodynamics and Laryngeal Mask Airway Insertion Conditions

Background: Laryngeal mask airway is a non invasive supraglottic device which has led to a radical change in the management of modern general anaesthesia. Propofol as a single agent is unsatisfactory and to overcome problems associated with LMA insertions. In the present study, we evaluated the haemodynamic changes and laryngeal mask airway insertion conditions comparing ketamine and opioids as adjuncts to propofol. Patients and Methods: 90 patients were randomly divided into 3 groups of 30 each. In Group PK-ketamine 0.5mg kg-1, in Group PF-fentanyl 1ug kg-1 and in Group PB - butorphanol 20ug kg-1 was given intravenously immediately before induction with propofol 2.5 mg kg-1. Jaw relaxation was assessed according to Young's criteria and the overall conditions according to modified Scheme of Lund and Stovener. Results: The mean total dose of propofol required in Group PK was 160.37 ± 15.75mg, in Group PF 156.22 ± 17.18 mg and in Group PB 140.08 ± 18.97 mg. The incidence of absolute jaw relaxation was highest in Group PB (93.33%) patients, intermediate in Group PF (53.33%) patients and lowest in Group PK i.e. 36.66% patients. Excellent insertion conditions were observed in 12 (40%) patients in Group PK and 13 (43.33%) patients in Group PF and in 26 (86.67%) patients in Group PB. Group PK showed more rise in systolic and diastolic blood pressure and heart rate post LMA insertion as compared to Group PF and Group PB. Conclusion: It is concluded that addition of butorphanol to propofol for LMA insertion provided absolute jaw relaxation and excellent insertion conditions with stable haemodynamics Side effects like coughing, gagging, lacrimation and laryngospasm were lower as compared to the other two groups.
The effect of developmental regulation on visual attention: The example of the "biological clock"

The current study investigated the attentional mechanisms associated with goal engagement and disengagement in a lifespan context. Women approaching the end of their childbearing years (N = 29) were compared with women who had passed that deadline (N = 28). Participants' goal engagement was measured with a goal nomination task, an incidental recall task of goal-relevant sentences, visual attention to goal-relevant vs. goal-irrelevant images, and a memory task of goal-relevant images. The attention data indicated that women approaching the deadline had a longer first fixation on baby images than women who had passed the deadline. This novel finding was supported by a replication of the previous finding that women approaching the deadline were more engaged with the goal of childbearing than women who had passed the deadline. The connection between attention and memory of goal-relevant information is explored as evidence of cognition working in the service of motivation and developmental regulation.
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

Summary: A tool to predict the effect that newly discovered genomic variants have on known transcripts is indispensible in prioritizing and categorizing such variants. In Ensembl, a web-based tool (the SNP Effect Predictor) and API interface can now functionally annotate variants in all Ensembl and Ensembl Genomes supported species. Availability: The Ensembl SNP Effect Predictor can be accessed via the Ensembl website at http://www.ensembl. org/. The Ensembl API (http://www.ensembl.org/info/docs/api/api_installation.html for installation instructions) is open source software. Contact: wm2@ebi.ac. uk; fiona@ebi.ac. uk Supplementary information: Supplementary data are available at Bioinformatics online.
Hybrid Deep Learning for Face Verification

This paper proposes a hybrid convolutional network (ConvNet)-Restricted Boltzmann Machine (RBM) model for face verification in wild conditions. A key contribution of this work is to directly learn relational visual features, which indicate identity similarities, from raw pixels of face pairs with a hybrid deep network. The deep ConvNets in our model mimic the primary visual cortex to jointly extract local relational visual features from two face images compared with the learned filter pairs. These relational features are further processed through multiple layers to extract high-level and global features. Multiple groups of ConvNets are constructed in order to achieve robustness and characterize face similarities from different aspects. The top-layer RBM performs inference from complementary high-level features extracted from different ConvNet groups with a two-level average pooling hierarchy. The entire hybrid deep network is jointly fine-tuned to optimize for the task of face verification. Our model achieves competitive face verification performance on the LFW dataset.
Association between standard clinical and pathologic characteristics and the 21‐gene recurrence score in breast cancer patients

The 21‐gene recurrence score (RS) assay has been reported to accurately predict the risk of disease recurrence and chemotherapy benefit in women with estrogen receptor (ER)‐positive, lymph node (LN)‐negative breast cancer who are treated with tamoxifen. To the authors' knowledge, the association between the RS and clinicopathologic characteristics has been studied in randomized and case‐control trials, but not in the general population.
The Novel Toll-Like Receptor 2 Agonist SUP3 Enhances Antigen Presentation and T Cell Activation by Dendritic Cells

Dendritic cells (DCs) are highly specialized antigen-presenting cells that play crucial roles in innate and adaptive immunity. Previous studies suggested that Toll-like receptor (TLR) agonists could be used as potential adjuvants, as activation of TLRs can boost DC-induced immune responses. TLR2 agonists have been shown to enhance DC-mediated immune responses. However, classical TLR2 agonists such as Pam3CSK4 are not stable enough in vivo, which limits their clinical applications. In this study, a novel structurally stable TLR2 agonist named SUP3 was designed. Functional analysis showed that SUP3 induced much stronger antitumor response than Pam3CSK4 by promoting cytotoxic T lymphocytes activation in vivo. This effect was achieved through the following mechanisms: SUP3 strongly enhanced the ability of antigen cross-presentation by DCs and subsequent T cell activation. SUP3 upregulated the expression of costimulatory molecules on DCs and increased antigen deposition in draining lymph nodes. More interestingly, SUP3 induced less amount of pro-inflammatory cytokine production in vivo compared to other TLR agonists such as lipopolysaccharide. Taken together, SUP3 could serve as a novel promising immune adjuvant in vaccine development and immune modulations.
Coronary and visceral vasoactivity associated with eating and digestion in the conscious dog.

VATNER, STEPHEN F. , DEAN FRANKLIN, AND ROBERT L. VAN CTTTERS. Goronmy and uixmzl uasoactioity associated with eating and digestion in the conscious dog. Am. J. Physiol. 219(5):1380-1385. 1970. -The modifications in regional blood flow and vasoactivity in response to eating and digestion were studied in conscious dogs after full recovery from instrumentation with ultrasonic or electromagnetic flow probes on the ascending aorta, left circumflex coronary, mesenteric, renal and iliac arteries, and miniature pressure gauges in the aorta. The presentation and ingestion of food by the resting conscious dog caused cardiac output (62yQ), arterial pressure (33%), heart rate ( 79y0), mesenteric resistance (4@&), and renal resistance (24y0) to increase transiently while iliac (337~) and coronary (62y0) resistance decreased transiently. Mesenteric flow began to increase within 5 min after eating and reached a peak of 132y0 b a ove control within 30-90 min (avg 55 min) and gradually returned to preprandial control levels over the next 2-6 hr. Iliac flow was decreased slightly (10%) 30-60 min postprandially as long as the dog did not walk about. Within lo-30 min renal and coronary flow and resistance returned to preprandial control levels and remained there during peak mesenteric vasodilatation.
Eating out of home in Vietnamese adolescents: socioeconomic factors and dietary associations.

BACKGROUND Out-of-home (OH) eating in developed countries is associated with suboptimal dietary intakes, but evidence is scarce on the situation in developing countries. OBJECTIVE The objective of this study was to determine the nutritional contribution of OH eating and related socioeconomic determinants in Vietnamese adolescents. DESIGN A 24-h recall was used to collect food intake data in a cross-sectional study of 1172 adolescents living in urban and rural areas. Multilevel analysis compared the mean daily intakes of energy, energy density, energy from fat, food groups, vitamin A, iron, and zinc in low, middle, and high consumers of OH food. Socioeconomic associations of OH eating were analyzed in a subsample of 870 adolescents. RESULTS OH foods contributed 42% of fruit and vegetables, 23% of sodium, 21% of energy, 21% of vitamin A, 21% of iron, and 21% of zinc consumed per day. OH eating was negatively associated with total energy intake and energy density and positively associated with dietary diversity, energy contribution from fat, and consumption of sugar products. In rural areas, OH eating was positively associated with iron, fruit, meat, poultry, and offal intake. Female sex (P < 0.001), residence in urban areas (P < 0.001), and amount of pocket money (P < 0.001) were positively associated with consumption of OH foods. CONCLUSIONS OH eating added a number of desirable foods and nutrients but was also associated with higher consumption of energy from fat and sugar products. Independent of household wealth and locality, pocket money and sex are important determinants of OH eating.
Cognitive Styles and Approaches To Studying in Management Education

This article examines the role of intuition and/or analysis cognitive styles and approaches to studying in business education. The Cognitive Style Index (CSI) and Revised Approaches to Studying Inventory (RASI) were administered to 222 American undergraduate business students. The authors found a relationship between analytic orientation and grade point average. Furthermore, the authors found a correlation between academic performance and higher scores on the Deep, Strategic, Metacognitive Awareness, and Academic Self-Confidence Scales of the RASI. Women adopted a more analytic style and scored higher on the Surface and Strategic Scales of the RASI. The authors discuss implications of these findings for management education.