Miracle-dz/UniFAR-FTUs huggingface dataset:
SAYING SOMETHING FOR A PARTICULAR PURPOSE: CONSTRUCTIONAL COMPATIBILITY AND CONSTRUCTIONAL FAMILIES

This paper explores the compatibility of a group of speech predicates (i.e. speech verbs used to saying something for a particular purpose or with a specific result) with six constructional patterns (i.e. transitive construction, that-construction, motion construction, caused-motion construction, way construction, and resultative construction). In so doing, the present corpus-based research offers additional evidence in support of the hypothesis that constructional compatibility is semantically and pragmatically grounded. It is further argued that lexico-constructional compatibility can be either blocked or licensed by the different internal and external constraints at work in each concrete subsumption process. Finally, we point to the need of distinguishing between central and more peripheral instances of the same grammatical construction. In most cases, peripheral members will be shown to be metonymic extensions, thus providing yet another case in favor of metonymic links as a relevant type of inheritance link in the configuration of constructional families.
Dose-Response Associations Between Number and Frequency of Substance Use and High-Risk Sexual Behaviors Among HIV-Negative Substance-Using Men Who Have Sex With Men (SUMSM) in San Francisco

Abstract: We evaluated the relationship between frequency and number of substances used and HIV risk [ie, serodiscordant unprotected anal intercourse (SDUAI)] among 3173 HIV-negative substance-using MSM. Compared with nonusers, the adjusted odds ratio (AOR) for SDUAI among episodic and at least weekly users, respectively, was 3.31 [95% confidence interval (CI), 2.55 to 4.28] and 5.46 (95% CI, 3.80 to 7.84) for methamphetamine, 1.86 (95% CI, 1.51 to 2.29) and 3.13 (95% CI, 2.12 to 4.63) for cocaine, and 2.08 (95% CI, 1.68 to 2.56) and 2.54 (95% CI, 1.85 to 3.48) for poppers. Heavy alcohol drinkers reported more SDUAI than moderate drinkers [AOR, 1.90 (95% CI, 1.43 to 2.51)]. Compared with nonusers, AORs for using 1, 2, and ≥3 substances were 16.81 (95% CI, 12.25 to 23.08), 27.31 (95% CI, 18.93 to 39.39), and 46.38 (95% CI, 30.65 to 70.19), respectively. High-risk sexual behaviors were strongly associated with frequency and number of substances used.
The Xiphophorus‐derived antibody, XMEL, shows sensitivity and specificity for human cutaneous melanoma but is not a prognostic marker

XMEL is a monoclonal antibody raised against part of the extracellular domain of the putative tyrosine kinase receptor protein implicated in the pathogenesis of melanoma formation in the Xiphophorus fish melanoma model. Our objective in this study was to determine the diagnostic and prognostic utility of XMEL for human melanoma. Formalin‐fixed tissue from 82 melanomas, 42 carcinomas, 23 neural tumors, 12 lymphomas and 12 sarcomas were immunostained with XMEL and compared with a widely used melanoma antibody, HMB‐45. The sensitivity of HMB‐45 (83.1%) was similar to that of XMEL (79.8%). XMEL detected 7 melanomas that were HMB‐45 negative. Specificity for detection of melanoma was greater with HMB‐45 (95.5%) as compared to XMEL (80.9%). Of interest, all 4 prostatic adenocarcinomas were XMEL positive. These data suggest that XMEL is as sensitive but not as specific as HMB‐45 in the detection of cutaneous melanoma but may serve as an ancillary antibody to improve diagnostic yield. The consistent positivity of XMEL in melanoma lends support to the hypothesis that the detected protein plays a role in melanoma pathogenesis. XMEL reactivity is not an independent prognosticator of death from melanoma in 37 melanomas from patients with at least 10 years' follow‐up. These data and the fact that XMEL shows variable reactivity with metastatic melanomas but almost 100% reactivity with the primary melanomas suggest that the antigen recognized by the XMEL antibody may be important in the early stages of melanoma progression. This is supported by our earlier observation that XMEL is reactive with dysplastic nevi, a precursor of malignant melanoma.
A theoretical overview and empirical study of mediated learning experience: Prediction of preschool performance from mother‐infant interaction patterns

This research is based on a 4-year longitudinal study of 51 normal, low SES infants and their mothers. It was conducted at the Clinical Infant Development Program sponsored by the Clinical Infant-Child Development Research Center (NIMH-HRSA). Infants' free-play sessions with their mothers were analyzed at 4, 8, 12, 24, and 36 months of age by use of an observation method based on Feuerstein's theory of Mediated Learning Experience (MLE). The participating children were tested with the Bayley Scales (to age 2 years) and the McCarthy Scales (at 36 and 48 months). Ten-minute observations of motherchild interactions, which used molar criteria of observation based on MLE theory, predicted cognitive performance at 2, 3, and 4 years of age. The observation made at 12 months was most predictive of long-term cognitive performance. Mother-infant interaction patterns were less predictive of cognitive performance in infancy than they were of performance at 2, 3, and 4 years of age. Each of the observed MLE criteria increased with age, although the frequency of some of the criteria remained low throughout the study. Stability of all MLE criteria was significant across most comparisons over time.
Reactive scheduling in holonic manufacturing systems : Architecture, dynamic model and co-operation strategy

: This paper presents an architecture for reactive scheduling that enables concurrent scheduling and schedule execution. When disturbances occur, the system reacts to them at several levels: an on-line shop floor control system reacts immediately, and the reactive scheduler responds more slowly, but with a higher response time. This approach enables a good combination of performance optimisation and reaction to disturbances. A Petri net models the co-operation strategy.
Combining Eye Gaze Input With a Brain–Computer Interface for Touchless Human–Computer Interaction

A Brain–Computer Interface (BCI) provides a new communication channel for severely disabled people who have completely or partially lost control over muscular activity. It is questionable whether a BCI is the best choice for controlling a device if partial muscular activity still is available. For example, gaze-based interfaces can be utilized for people who are still able to control their eye movements. Such interfaces suffer from the lack of a natural degree of freedom for the selection command (e.g., a mouse click). One workaround for this problem is based on so-called dwell times, which easily leads to errors if the users do not pay close attention to where they are looking. We developed a multimodal interface combining eye movements and a BCI to a hybrid BCI, resulting in a robust and intuitive device for touchless interaction. This system especially is capable of dealing with different stimulus complexities.
Towards Optimized Packet Classification Algorithms for Multi-Core Network Processors

In this paper, a novel packet classification scheme optimized for multi-core network processors is proposed. The algorithm, Explicit Cuttings (ExpCuts), adopts a hierarchical space aggregation technique to significantly reduce the memory usage. Consequently, without burst of memory usages, the time-consuming linear search in the conventional decision-tree based packet classification algorithms is eliminated, and an explicit worst-case search time is achieved. To evaluate the performance of ExpCuts, we implement the algorithm, as well as HiCuts and HSM, on the Intel IXP2850 network processor. Experimental results show that ExpCuts outperforms the existing best- known algorithms in terms of memory usage and classification speed.
Focal Low and Global High Permeability Predict the Possibility, Risk, and Location of Hemorrhagic Transformation following Intra-Arterial Thrombolysis Therapy in Acute Stroke

BACKGROUND AND PURPOSE: The contrast volume transfer coefficient (Ktrans), which reflects blood-brain barrier permeability, is influenced by circulation and measurement conditions. We hypothesized that focal low BBB permeability values can predict the spatial distribution of hemorrhagic transformation and global high BBB permeability values can predict the likelihood of hemorrhagic transformation. MATERIALS AND METHODS: We retrospectively enrolled 106 patients with hemispheric stroke who received intra-arterial thrombolytic treatment. Ktrans maps were obtained with first-pass perfusion CT data. The Ktrans values at the region level, obtained with the Alberta Stroke Program Early CT Score system, were compared to determine the differences between the hemorrhagic transformation and nonhemorrhagic transformation regions. The Ktrans values of the whole ischemic region based on baseline perfusion CT were obtained as a variable to hemorrhagic transformation possibility at the global level. RESULTS: Forty-eight (45.3%) patients had hemorrhagic transformation, and 21 (19.8%) had symptomatic intracranial hemorrhage. At the region level, there were 82 ROIs with hemorrhagic transformation and parenchymal hemorrhage with a mean Ktrans, 0.5 ± 0.5/min, which was significantly lower than that in the nonhemorrhagic transformation regions (P < .01). The mean Ktrans value of 615 nonhemorrhagic transformation ROIs was 0.7 ± 0.6/min. At the global level, there was a significant difference (P = .01) between the mean Ktrans values of patients with symptomatic intracranial hemorrhage (1.3 ± 0.9) and those without symptomatic intracranial hemorrhage (0.8 ± 0.4). Only a high Ktrans value at the global level could predict the occurrence of symptomatic intracranial hemorrhage (P < .01; OR = 5.04; 95% CI, 2.01–12.65). CONCLUSIONS: Global high Ktrans values can predict the likelihood of hemorrhagic transformation or symptomatic intracranial hemorrhage at the patient level, whereas focal low Ktrans values can predict the spatial distributions of hemorrhagic transformation at the region level.
Cholera outbreaks in Malawi in 1998-2012: social and cultural challenges in prevention and control.

INTRODUCTION Cholera still remains a significant cause of morbidity and mortality in developing countries, although comprehensive surveillance data to inform policy and strategies are scarce. METHODOLOGY A desk review of the national cholera database and zonal and districts reports was conducted. Interviews were conducted with district health management teams, health workers, and participants in communities in six districts affected by cholera in 2011/2012 to obtain data on water, sanitation, and sociocultural issues. RESULTS From 1998 to 2012, cholera outbreaks occurred every year in Malawi, with the highest number of cases and deaths reported in 2001/2002 (33,546 cases, 968 deaths; case fatality rate [CFR] 2.3%). In 2011/2012, cholera outbreak was widespread in the southern region, affecting 10 out of 13 districts, where 1,806 cases and 38 deaths (CFR 2.1%) were reported. Unsafe water sources, lack of maintenance of broken boreholes, frequent breakdown of piped water supply, low coverage of pit latrines (range 40%-60%), lack of hand washing facilities (< 5%), salty borehole water, fishermen staying on Lake Chilwa, cross-border Malawi-Mozambique disease spread, and sociocultural issues were some of the causes of the persistent cholera outbreaks in Malawi. CONCLUSIONS Despite improvements in safe drinking water and sanitation, cholera is still a major public health problem. Introduction of a community-led total sanitation approach, use of social and cultural information in community mobilization strategies, and introduction of an oral cholera vaccine could help to eliminate cholera in Malawi.
Exact distribution of individual displacements in linear probing hashing

This paper studies the distribution of individual displacements for the standard and the Robin Hood linear probing hashing algorithms. When the a table of size m has n elements, the distribution of the search cost of a random element is studied for both algorithms. Specifically, exact distributions for fixed m and n are found as well as when the table is α-full, and α strictly smaller than 1. Moreover, for full tables, limit laws for both algorithms are derived.
Rho Kinase Inhibition Improves Endothelial Function in Human Subjects With Coronary Artery Disease

Investigations from basic biology suggest that activation of the Rho/Rho kinase pathway reduces the bioavailability of nitric oxide (NO) and thereby promotes atherosclerosis and its clinical complications. Yet, little information is available about the relationship of the Rho/Rho kinase pathway to NO bioavailability in humans with atherosclerosis. Accordingly, we determined whether inhibition of Rho kinase augments NO bioavailability and improves endothelial function in human subjects with coronary artery disease (CAD). Thirteen CAD subjects and 16 age- and sex-matched healthy controls were randomly assigned to receive the Rho kinase inhibitor, fasudil, or placebo for 1 month each in a double-blind crossover trial. Flow-mediated, endothelium-dependent and nitroglycerin-induced, endothelium-independent vasodilation were assessed by brachial artery ultrasonography. Rho kinase activity was measured in peripheral leukocytes. Fasudil increased endothelium-dependent vasodilation in CAD subjects from 9.4±1.9% to 13.4±1.9% (P=0.001) but not in healthy controls (from 11.3±1.4% to 7.7±1.1%; P=0.07). Endothelium-independent vasodilation was not affected by fasudil in either CAD or healthy subjects. Fasudil reduced Rho kinase activity by 59±18% in CAD subjects (P=0.001) but not in healthy subjects (by 3±6%; P=0.60). The change in endothelium-dependent vasodilation achieved with fasudil relative to placebo was inversely proportional to Rho kinase inhibition (ie, greater Rho kinase inhibition was associated with larger improvement in endothelium-dependent vasodilation) (r=−0.48; P=0.01). These findings suggest that Rho/Rho kinase activation promotes endothelial dysfunction in humans with atherosclerosis. Inhibition of the Rho/Rho kinase pathway should provide a useful strategy to restore NO bioavailability in humans with atherosclerosis.
Oral lichen planus in childhood

In two patients in whom diclofenac" and lithium carbonate"* were considered to be responsible for linear IgA dermatosis. the bullous eruption appeared 12 months after the start of these medications, in contrast with the brief delay of approximately 10 days seen with vancomycin. There was a recurrence of lesions in both cases when therapy was reintroduced. but in the patient on lithium carbonate the skin lesions disappeared within a week of starting dapsone therapy, despite continuation of lithium. Godfrey et a! '* reported a series of 70 cases of linear IgA dermatosis in which they studied various associations. A subgroup of 35 patients was assessed with regard to possible triggering factors. They considered that drugs, particularly non-steroidal anti-inflammatory agents and antibiotics, might possibly have triggered the eruption in some patients. A number of these patients also had associated pathology, including severe respiratory tract infection, and burns/ trauma. The role of vancomycin in triggering linear IgA dermatosis appears to be clearly established, on the basis of development of the eruption after a relatively constant interval from the start of treatment, and regression after its discontinuation. In addition. it is noteworthy that the second biopsy in our patient was negative on immunofluorescence. However, the mechanism whereby vancomycin triggers the eruption is unknown. Is it directly responsible for the production of igA antibodies directed against certain proteins of the basement membrane, as some authors have shown in idiopathic IgA disease. ' "* or does it only act as a triggering factor in predisposed patients who have other background pathology?
Lemons, Market Shutdowns and Learning

I study a dynamic economy featuring adverse selection in financial markets. Investment is undertaken by borrowing-constrained entrepreneurs. They sell their past projects to finance new ones, but asymmetric information about project quality creates a lemons problem. The magnitude of this friction responds to aggregate shocks, amplifying the responses of asset prices and investment. Indeed, negative shocks can lead to a complete shutdown in financial markets. I then introduce learning from past transactions. This makes the degree of informational asymmetry endogenous and makes the liquidity of assets depend on the experience of market participants. Market downturns lead to less learning, worsening the future adverse selection problem. As a result, transitory shocks can create highly persistent responses in investment and output. (JEL E22, E44, D83, G14)
Enterprise systems and labor productivity : disentangling combination effects

This study analyzes the relationship between the three main enterprise systems (Enterprise Resource Planning (ERP), Supply Chain Management (SCM), Customer Relationship Management (CRM)) and labor productivity. It reveals the performance gains due to different combinations of these systems. It also tests for complementarity among the enterprise systems with respect to their interacting nature. Using German firm-level data the results show that the highest productivity gains due to enterprise system usage are realized through use of the three main enterprise systems together. In addition, SCM and CRM function as complements, especially if ERP is also in use.
Sibling-Implemented Intervention for Skill Development With Children With Disabilities

The research synthesis presented here reviewed the currently available evidence on the effectiveness of sibling-implemented interventions for their siblings with disabilities. The search for appropriate research literature spanned from 1975 to 2008 and resulted in a total of eight studies that met the inclusion criteria. All eight studies in this synthesis employed single-case design as the primary research methodology. The analysis of the eight studies is summarized into (a) experimental design and participants, (b) intervention features, (c) measurement procedures, and (d) findings. Taken together, the outcomes of this research synthesis provide support for the effectiveness of sibling-implemented intervention for children with disabilities. Furthermore, implications for further research are discussed including taking into account specific siblings’ characteristics (e.g., socialization, intellectual ability) and ensuring that future studies sufficiently address generalization and maintenance of intervention effect and collect rigorous data on implementation fidelity.
CSF Neuropeptides in Euthymic Bipolar Patients and Controls

Levels of vasopressin, somatostatin, neurotensin, vasoactive intestinal peptide, corticotrophin-releasing factor and adrenocorticotrophin in CSF were determined in lithium-treated and unmedicated euthymic bipolar patients and controls, in a search for a trait marker in affective disorder. No group differences in levels of these peptides were found. Highly significant positive correlations were found among these peptides (with the exception of neurotensin), suggesting that their presence in CSF is functionally significant, as opposed to the result of random diffusion from the interstitial space of the brain.
The Cambridge Handbook of Phonology: The interaction of tone, sonority, and prosodic structure

The aim of this chapter is to link the major aspects of suprasegmental phonology discussed in this part of the Handbook (i.e. tone – Yip Ch.10, Gussenhoven Ch.11; sonority – Zec Ch.8; prosodic structure – Zec Ch.8, Kager Ch.9). It shows how sonority and tone can both influence and be influenced by prosodic structure. It argues that there is a unifying theoretical mechanism that accounts for such influences and how this same mechanism accounts for interactions at all prosodic levels, from below the syllable to the Utterance. To illustrate the theoretical points, the initial empirical focus will be on the influence that sonority can have on foot structure, often called ‘sonority-driven stress’. Relevant data from the North New Guinea language Takia are provided in (1).
Vascular Endothelial Growth Factor and Microvascular Permeability

Vascular Endothelial Growth Factors (VEGFs) are endogenously produced vascular cytokines which result in angiogenesis, vasodilatation, and increased microvascular permeability in vivo. They are endothelial specific and result in mitosis, migration, stress fiber formation and increased permeability of endothelial cells in culture. They have been critically implicated in a host of pathological conditions including solid tumor growth and diabetes, and been proposed as a therapy for coronary and peripheral ischemic disease. However, the potent permeability‐enhancing properties of VEGFs are very poorly understood. The pharmacology, signal transduction pathways, intracellular signaling mechanisms, and ultrastructural changes which result in increased permeability are still not clear. This review discusses the available evidence for how VEGFs increase permeability in vivo, and some of the pitfalls in interpreting experiments which do not take into account the vasoactive properties of VEGFs. It also discusses the clinical implications of the permeability enhancing effect of VEGFs, and the relevance of these studies to development of new therapies.
An Attributional (Causal Dimensional) Analysis of Perceptions of Sexual Harassment1

Female and male subjects read one of three scenarios depicting a social-sexual interaction between a man and a woman. The scenarios varied in severity of the stimulus male's behavior according to whether sexual harassment had occurred. Subjects then rated the offensiveness of his behavior and whether it constituted sexual harassment. Subjects also rated the stimulus male's behavior on Weiner's (1986) three basic dimensions of causality: locus of causality, or the perceived cause of the behavior as internal or external; stability, or the likelihood of its recurrence; and controllability, or the amount of volitional influence he exercised during the interaction. Additionally, subjects reported their anger at the target male and sympathy for the target female. Findings generally indicated that for both women and men, as the scenarios increased in severity, these ratings were elevated. Gender comparisons also showed elevations in these ratings for female but not for male subjects, and only in the scenarios of lesser severity. Regression analyses revealed attribution variables—control, stability, and anger—as reliable predictors of perceived offensiveness and harassment in the most severe scenario, whereas affects were the most reliable predictors in scenarios of lesser severity. The implications of these findings for perception of sexual harassment are discussed.
Spiritual and Religious Transformation in Women Who Were Parentally Bereaved as Adolescents

This article is based on a larger research study that focused on how an adolescent girl's identity development is influenced by the death of a parent. A sample of 18 women was recruited for the study. This article highlights the transformation of these women's spiritual and religious beliefs as part of their identity development following the death of their parents. The different pathways the women took with respect to their views on religion and spirituality are exemplified in what follows, highlighting themes of struggle and connection.