Miracle-dz/UniFAR-FTUs huggingface dataset:
Linear code derived from the primage of quadratic function

Linear codes have been an interesting topic in both theory and practice for many years. In this paper, for an odd prime power $q$, we construct some class of linear code over finite field $\mathbb{F}_q$ with defining set be the preimage of general quadratic form function and determine the explicit complete weight enumerators of the linear codes. Our construction cover all the corresponding result with quadratic form function and they may have applications in cryptography and secret sharing schemes.
Nasal Deformity in Subjects with Class III Facial Deformities

Las deformidades dentofaciales presentan algunos matices y variaciones que determinan la inclusion de diferentes componentes anatomicos dentro de la enfermedad; el objetivo de esta investigacion es conocer las caracteristicas de la nariz en pacientes con deformidad dentofacial de clase III. Se desarrollo un estudio descriptivo en 20 pacientes con diagnostico de deformidad facial declase III e indicacion quirurgica; se estudiaron analisis fotograficos frontales y laterales asi como tomografias computadorizadas para analizar variables de morfologia nasal y deformidades asociadas al puente nasal, punta nasal y septo nasal. Los resultados demostraron que los angulos nasales se encuentran fuera de los parametros de normalidad y que el ancho basal de la nariz es aproximadamente 3 mm menor que el ancho intercantal; el 45% de los sujetos presento desviacion lateral, 50% deformidad del puente nasal y el 80% desvio de septo nasal. Se concluye que existen deformidades nasales en sujetos con deformidad facial de clase III y que este componente debe ser evaluado criteriosamente en la etapa preoperatoria.
ProliferationStimulation Promotes B Cell Activation and Species in Response to B Cell Receptor Prolonged Production of Reactive Oxygen

We have investigated the intracellular sources and physiological function of reactive oxygen species (ROS) produced in primary B cells in response to BCR stimulation. BCR stimulation of primary resting murine B cells induced the rapid production of ROS that occurred within minutes and was maintained for at least 24 h after receptor stimulation. While the early production of ROS (0–2 h) was dependent on the Nox2 isoform of NADPH oxidase, at later stages of B cell activation (6–24 h) ROS were generated by a second pathway, which appeared to be dependent on mitochondrial respiration. B cells from mice deﬁcient in the Nox2 NADPH oxidase complex lacked detectable early production of extracellular and intracellular ROS after BCR stimulation but had normal proximal BCR signaling and BCR-induced activation and proliferation in vitro and mounted normal or somewhat elevated Ab responses in vivo. In contrast, neutralizing both pathways of BCR-derived ROS with the scavenger N -acetylcysteine resulted in impaired in vitro BCR-induced activation and proliferation and attenuated BCR signaling through the PI3K pathway at later times. These results indicate that the production of ROS downstream of the BCR is derived from at least two distinct cellular sources and plays a critical role at the later stages of B cell activation by promoting sustained BCR signaling via the PI3K pathway, which is needed for effective B cell responses to Ag. The Journal of Immunology , 2012, 189: 000–000.
Formation of triads without the dihydropyridine receptor alpha subunits in cell lines from dysgenic skeletal muscle

Muscular dysgenesis (mdg/mdg), a mutation of the skeletal muscle dihydropyridine receptor (DHPR) alpha 1 subunit, has served as a model to study the functions of the DHPR in excitation-contraction coupling and its role in triad formation. We have investigated the question of whether the lack of the DHPR in dysgenic skeletal muscle results in a failure of triad formation, using cell lines (GLT and NLT) derived from dysgenic (mdg/mdg) and normal (+/+) muscle, respectively. The lines were generated by transfection of myoblasts with a plasmid encoding a Large T antigen. Both cell lines express muscle-specific proteins and begin organization of sarcomeres as demonstrated by immunocytochemistry. Similar to primary cultures, dysgenic (GLT) myoblasts show a higher incidence of cell fusion than their normal counterparts (NLT). NLT myotubes develop spontaneous contractile activity, and fluorescent Ca2+ recordings show Ca2+ release in response to depolarization. In contrast, GLTs show neither spontaneous nor depolarization-induced Ca2+ transients, but do release Ca2+ from the sarcoplasmic reticulum (SR) in response to caffeine. Despite normal transverse tubule (T-tubule) formation, GLT myotubes lack the alpha 1 subunit of the skeletal muscle DHPR, and the alpha 2 subunit is mistargeted. Nevertheless, the ryanodine receptor (RyR) frequently develops its normal, clustered organization in the absence of both DHPR alpha subunits in the T-tubules. In EM, these RyR clusters correspond to T-tubule/SR junctions with regularly spaced feet. These findings provide conclusive evidence that interactions between the DHPR and RyR are not involved in the formation of triad junctions or in the normal organization of the RyR in the junctional SR.
THE STRENGTH OF STUD SHEAR CONNECTORS

Results are described of tests on 47 push-out specimens designed to study the strength of stud shear connectors for composite steel and concrete construction. Different stud steels, two concrete types, and variations in concrete strength were examined, specimens with studs of different dimensions and having slabs with and without reinforcement were also tested. The shear stress-slip curves for low loads were predictable by modelling the connectors as a flexible elastic dowel on an elastic foundation. For high loads an empirical expression is developed defining the relative influences of the variables examined. The test results are compared with those of other investigators and with the requirements of the AISC specification and the British code CP 117. /A/
The OmpL37 Surface-Exposed Protein Is Expressed by Pathogenic Leptospira during Infection and Binds Skin and Vascular Elastin

Pathogenic Leptospira spp. shed in the urine of reservoir hosts into freshwater can be transmitted to a susceptible host through skin abrasions or mucous membranes causing leptospirosis. The infection process involves the ability of leptospires to adhere to cell surface and extracellular matrix components, a crucial step for dissemination and colonization of host tissues. Therefore, the elucidation of novel mediators of host-pathogen interaction is important in the discovery of virulence factors involved in the pathogenesis of leptospirosis. In this study, we assess the functional roles of transmembrane outer membrane proteins OmpL36 (LIC13166), OmpL37 (LIC12263), and OmpL47 (LIC13050), which we recently identified on the leptospiral surface. We determine the capacity of these proteins to bind to host tissue components by enzyme-linked immunosorbent assay. OmpL37 binds elastin preferentially, exhibiting dose-dependent, saturating binding to human skin (Kd, 104±19 nM) and aortic elastin (Kd, 152±27 nM). It also binds fibrinogen (Kd, 244±15 nM), fibrinogen fragment D (Kd, 132±30 nM), plasma fibronectin (Kd, 359±68 nM), and murine laminin (Kd, 410±81 nM). The binding to human skin elastin by both recombinant OmpL37 and live Leptospira interrogans is specifically enhanced by rabbit antiserum for OmpL37, suggesting the involvement of OmpL37 in leptospiral binding to elastin and also the possibility that host-generated antibodies may promote rather than inhibit the adherence of leptospires to elastin-rich tissues. Further, we demonstrate that OmpL37 is recognized by acute and convalescent leptospirosis patient sera and also by Leptospira-infected hamster sera. Finally, OmpL37 protein is detected in pathogenic Leptospira serovars and not in saprophytic Leptospira. Thus, OmpL37 is a novel elastin-binding protein of pathogenic Leptospira that may be promoting attachment of Leptospira to host tissues.
Automatic construction of intelligent diagram editors

The intelligent diagram is a recent metaphor for dia-gramming in which the underlying graphic editor parses the diagram as it is being constructed, performing error correction and collecting geometric constraints which capture the relationships between diagram components. During diagram manipulation a constraint solver uses these geometric constraints to maintain the diagram’s semantics. We describe the Penguins system. This auto-mates the development of graphical editors that support the intelligent diagram metaphor. It takes a grammatical speci(cid:12)cation of a particular diagram language and generates an editor that supports the creation, manipulation and parsing of diagrams in that visual language. Our empirical results show that the system can be used to generate specialized editors for a wide variety of diagram languages, ranging from state transition diagrams to mathematical equations, with real-time incremental parsing, error correction and direct manipulation.
Successful measurement of Content Management System implementation

It's a required for higher education institution to implement a system that supports learning and teaching processes. Using Content Management Systems (CMS) helped the institution to improve learning quality. aims to evaluate user satisfaction at Bina Nusantara University as case study. Bina Nusantara University, itself already implement CMS since 15 years ago which call with Binusmaya and along the year proved helps many Subject Matter Expert (SME) to create content material, on the other hand, the course number are increase and complexity of content making difficult to monitor and some important feature is not available. This study focuses on critical success factor from user perception. A questionnaire created according to Delone & McLean Information System Impact Model and divided into 2 sections, which is closed question and open question. Questionnaires answered by respondents who are 80% have experience using Binusmaya system more than 1 year and as a result, only 47% user satisfied using Binusmaya system and some recommendation about what feature need to be added.
Assessing Sexual Arousal with Adolescent Males Who Have Offended Sexually: Self-Report and Unobtrusively Measured Viewing Time

Sexual arousal was assessed using three approaches: the Affinity (Version. 1.0) computerized assessment of unobtrusively measured viewing time (VT), Affinity self-report ratings of sexual attractiveness, and a self-report sexual arousal graphing procedure. Data were collected from 78 males, aged 12–18 (M=15.09; SD=1.62), who acknowledged their sexual assaults. The pattern of responses to all three assessment techniques was remarkably similar, with maximal sexual interest demonstrated and reported for adolescent and adult females. Both self-report procedures could significantly distinguish those adolescents who assaulted a child from those who assaulted peers or adults. The self-report procedures could also significantly discriminate those adolescents with male child victims. The Affinity VT approach significantly differentiated those adolescents who assaulted male children from those who assaulted other individuals. No assessment technique could accurately identify those adolescents with exclusively female child victims. Overall, the results suggest that structured, self-report data regarding sexual interests can be useful in the assessment of adolescents who have offended sexually.
Biomechanical Comparison of Arthroscopic Single- and Double-Row Repair Techniques for Acute Bony Bankart Lesions

Background: Single- and double-row arthroscopic reconstruction techniques for acute bony Bankart lesions have been described in the literature. Hypothesis: The double-row fixation technique would provide superior reduction and stability of a simulated bony Bankart lesion at time zero in a cadaveric model compared with the single-row technique. Study Design: Controlled laboratory study. Methods: Testing was performed on 14 matched pairs of glenoids with simulated bony Bankart fractures with a defect width of 25% of the glenoid diameter. Half of the fractures were repaired with a double-row technique, while the contralateral glenoids were repaired with a single-row technique. The quality of fracture reduction was measured with a coordinate measuring machine. To determine the biomechanical stability of the repairs, specimens were preconditioned with 10 sinusoidal cycles between 5 and 25 N at 0.1 Hz and then pulled to failure in the anteromedial direction at a rate of 5 mm/min. Loads at 1 mm and 2 mm of fracture displacement were determined. Results: The double-row technique required significantly higher forces to achieve fracture displacements of 1 mm (mean, 60.6 N; range, 39.0-93.3 N; P = .001) and 2 mm (mean, 94.4 N; range, 43.4-151.2 N; P = .004) than the single-row technique (1 mm: mean, 30.2 N; range, 14.0-54.1 N and 2 mm: mean, 63.7 N; range, 26.6-118.8 N). Significantly reduced fracture displacement was seen after double-row repair for both the unloaded condition (mean, 1.1 mm; range, 0.3-2.4 mm; P = .005) and in response to a 10-N anterior force applied to the defect (mean, 1.6 mm; range, 0.5-2.7 mm; P = .001) compared with single-row repair (unloaded: mean, 2.1 mm; range, 1.3-3.4 mm and loaded: mean, 3.4 mm; range, 1.9-4.7 mm). Conclusion: The double-row fixation technique resulted in improved fracture reduction and superior stability at time zero in this cadaveric model. Clinical Relevance: This information may influence the surgical technique used to treat large osseous Bankart fractures and the postoperative rehabilitation protocols implemented when such repair techniques are used.
The Argo YBJ Daq System and the GRID Based Data Transfer

The Argo-YBJ experiment has now reached its final design configuration. The detector system consists of a full coverage array (about 5800 square meters) of resistive plate chambers (RPCs). The throughput depends on the trigger rate and threshold. The DAQ system must be able to sustain a maximum transfer rate of the order of 15 MB/s and a high peak data flow. Data are read out using a typical front-end acquisition chain built around a custom bus. Specialized electronics have been designed and dedicated software has been written to perform this task. Data are sent to the online farm through a switch exploiting a gigabit ethernet protocol. A solution to transfer data from the YBJ laboratory to the laboratories belonging to the Argo-YBJ collaboration exploiting the GRID middleware has also been implemented. In this paper we describe the daq and the data mover main characteristics and performance.
Ischemic Postconditioning Protects Liver From Ischemia-Reperfusion Injury by Modulating Mitochondrial Permeability Transition

Background. We tested the effectiveness of ischemic postconditioning (iPoC) in mitigating ischemia-reperfusion (I/R) injury of liver and the mechanism involves inhibiting the opening of the mitochondrial permeability transition pore (mPTP). Methods. iPoC, performed by three cycles of 1 min I/R of the liver, was tested on a partial liver I/R model on rats. The serum alanine transaminase levels, terminal deoxynucleotidyl transferase dUTP nick-end labeling staining, cytochrome c release, the formation of 4-hydroxy-2-nonnenal-modified proteins, and mitochondrial membrane potential (&Dgr;&psgr;m) were measured. Atractyloside (ATR) and NIM811, which modify the opening of mPTP, were administered in selected groups. Results. iPoC, and NIM811, diminished the elevation of serum alanine transaminase level after I/R injury (174.0±28.3 U/L for iPoC; 94.3±25.4 U/L for control+NIM811) when compared with others (416.3±16.7 U/L for control, 557.0±86.7 U/L for iPoC+ATR, P<0.05). The expressions of cytosolic cytochrome c after I/R injury were decreased in iPoC and control+NIM811 groups when compared with others. After I/R, the apoptosis and the 4-hydroxy-2-nonnenal-modified proteins were attenuated in iPoC group when compared (apoptotic counts/50 HPF: 723.3±98.7 for iPoC, 1274±201.2 for control, 1057.6±39 for iPoC+ATR, P<0.05). The &Dgr;&psgr;m measured by flow cytometry was better preserved in iPoC and NIM811 groups. Conclusions. iPoC attenuated cell deaths after I/R injury of liver. The protective effects were negated by the addition of ATR—a mPTP opener—and mimicked by injection of NIM811—a mPTP opening inhibitor. The study indicated iPoC conferred protection by modulating mPTP.
Anatomy of Escherichia coli σ70 promoters

Information theory was used to build a promoter model that accounts for the −10, the −35 and the uncertainty of the gap between them on a common scale. Helical face assignment indicated that base −7, rather than −11, of the −10 may be flipping to initiate transcription. We found that the sequence conservation of σ70 binding sites is 6.5 ± 0.1 bits. Some promoters lack a −35 region, but have a 6.7 ± 0.2 bit extended −10, almost the same information as the bipartite promoter. These results and similarities between the contacts in the extended −10 binding and the −35 suggest that the flexible bipartite σ factor evolved from a simpler polymerase. Binding predicted by the bipartite model is enriched around 35 bases upstream of the translational start. This distance is the smallest 5′ mRNA leader necessary for ribosome binding, suggesting that selective pressure minimizes transcript length. The promoter model was combined with models of the transcription factors Fur and Lrp to locate new promoters, to quantify promoter strengths, and to predict activation and repression. Finally, the DNA-bending proteins Fis, H-NS and IHF frequently have sites within one DNA persistence length from the −35, so bending allows distal activators to reach the polymerase.
A Simple Multipath Delay Estimator Based on Alternating Projection Algorithm

Multipath propagation causes errors to delay esti- mates and, thus, to location estimates. There exist a number of multipath error reduction techniques including delay lock loops with a narrow correlator spacing and multiparameter techniques like the maximum likelihood method, which typically are computationally rather demanding. This paper proposes a computationally simple multipath estimator based on the alternating projection (AP) algorithm, which is a way to solve the maximum likelihood problem. The algorithm uses the outputs of the code matched filter or the correlator bank, applies the AP algorithm simplified as much as possible to the found peak and, finally, interpolates to increase accuracy. The simulation results show that the multipath estimation capability of the proposed algorithm is better than that of the similar estimator using a single path model and the instantaneous early-late estimator. I. INTRODUCTION
Effect of insoluble fiber supplementation applied at different ages on digestive organ weight and digestive enzymes of layer-strain poultry

Abstract Two experiments were conducted to study effects of dietary insoluble fiber (IF) on digestive enzyme function in layer poultry. In Experiment 1, 8 wk old pullets were fed a control diet (Group C) or a diet (Group IF) supplemented with 1% IF (Arbocel RC). After 5 wk, 6 pullets per group were killed and organ samples collected. The remaining pullets in Group C were divided into two groups: half were fed the control diet (Group C) and half were given the IF diet (Group C-IF). Similarly, half the pullets in Group IF continued on the IF diet (Group IF) and half on the control diet (Group IF-C). At 10 wk, organ samples were collected. BW at wk 5 (IF, 1364.8g; C, 1342.9g) and 10 wk (IF, 1678.1g; IF-C, 1630.5g; C-IF, 1617.1g; C, 1580.4g) were not different. At wk 5, the relative proventricular weight (0.41 g/100g BW) and activities of pepsin (75.3 pepsin units/g proventriculus/min) and pancreatic general proteolytic activity (GP) (122.9 μmol tyrosine produced/g tissue) were greater (P < 0.05) than those of Group C (proventricular relative weight, 0.36; pepsin activity, 70.6; GP activity, 94.3). At wk 10, relative weights of liver and gizzard of Group IF were heavier (P < 0.05) than other treatments; activities of pepsin, GP, trypsin and chymotrypsin of IF pullets were significantly greater than other treatments as was mRNA expression for pepsinogens A (25.9 vs. 22.9) and C (13.1 vs. 10.8). In Experiment 2, 19 wk old hens were fed a control diet or a diet containing 0.8% IF (Arbocel RC) for 12 wk. Final BW after 12 wk was not different (IF, 1919.4 g; C, 1902.1 g). Pancreatic GP activity was greater (P < 0.05) in Group IF hens than Group C at wk 12 (122.2 vs. 97.0 μmol tyrosine released/min/g tissue)) as was relative gizzard weight (1.32 vs 1.10 g/100 g BW). The significantly improved digestive organ weights and enzyme activities in IF pullets may contribute to an improvement in feed utilization.
Divergent Cortical Generators of MEG and EEG during Human Sleep Spindles Suggested by Distributed Source Modeling

Background Sleep spindles are ∼1-second bursts of 10–15 Hz activity, occurring during normal stage 2 sleep. In animals, sleep spindles can be synchronous across multiple cortical and thalamic locations, suggesting a distributed stable phase-locked generating system. The high synchrony of spindles across scalp EEG sites suggests that this may also be true in humans. However, prior MEG studies suggest multiple and varying generators. Methodology/Principal Findings We recorded 306 channels of MEG simultaneously with 60 channels of EEG during naturally occurring spindles of stage 2 sleep in 7 healthy subjects. High-resolution structural MRI was obtained in each subject, to define the shells for a boundary element forward solution and to reconstruct the cortex providing the solution space for a noise-normalized minimum norm source estimation procedure. Integrated across the entire duration of all spindles, sources estimated from EEG and MEG are similar, diffuse and widespread, including all lobes from both hemispheres. However, the locations, phase and amplitude of sources simultaneously estimated from MEG versus EEG are highly distinct during the same spindles. Specifically, the sources estimated from EEG are highly synchronous across the cortex, whereas those from MEG rapidly shift in phase, hemisphere, and the location within the hemisphere. Conclusions/Significance The heterogeneity of MEG sources implies that multiple generators are active during human sleep spindles. If the source modeling is correct, then EEG spindles are generated by a different, diffusely synchronous system. Animal studies have identified two thalamo-cortical systems, core and matrix, that produce focal or diffuse activation and thus could underlie MEG and EEG spindles, respectively. Alternatively, EEG spindles could reflect overlap at the sensors of the same sources as are seen from the MEG. Although our results generally match human intracranial recordings, additional improvements are possible and simultaneous intra- and extra-cranial measures are needed to test their accuracy.
Self-regulatory Efficacy as a Mediator between Attributions and Intention for Health-related Physical Activity

The purpose of the present study was to examine whether self-regulatory efficacy would mediate the relationship between individual attributional dimensions for typical exercise levels and intentions to maintain these levels during final exams among university students. Using a prospective design, participants completed measures of attributions for typical activity levels, self-regulatory efficacy and intention to be active during a forthcoming exam period. Results revealed that self-regulatory efficacy partially mediated the relationship between attributional dimensions and intentions for both moderate and mild exercise levels. The results provide initial support for the suggestion that when examining moderate and mild intensity exercise, it is plausible that causality flows from stability of attributions to intentions, at least partially through self-regulatory efficacy.