Miracle-dz/UniFAR-FTUs huggingface dataset:
An Individualized Music Intervention for Agitation

Persons with cognitive impairment as in Alzheimer's disease and related disorders have a progressive decline in their stress threshold. Agitation results when this stress threshold is exceeded. A proposed mid-range theory incorporates these elements to discuss the use of individualized music to alleviate agitation. Music may provide a method of communicating with this population even in advanced stages when the person is unable to understand verbal language and has decreased ability to interpret environmental stimuli. It is predicted that the presentation of music carefuUy selected for meaningfulness to the person during his or heryoungeryears wil stimulate memory for remote events, and elicitation of memories associated with positive feelings will have a soothing effect and will alleviate or decrease agitated behaviors. Results from a pilot study andpreliminaryfindingsfrom a study currently underway are provided as beginning efforts to support this mid-range theory. An individualized music intervention that flows from this mid-range theory is discussed.
Hey Mom, What’s on Your Facebook? Comparing Facebook Disclosure and Privacy in Adolescents and Adults

People of all ages are increasingly exposed to online environments that encourage them to share and connect with others. However, there is a perception that adolescents are particularly susceptible to these cues and share more online than do other age groups. With a group of 288 adolescents and 285 adults, we explored differences and similarities in use of Facebook for information sharing and use of the controls to protect their privacy. Adolescents reported disclosing more information on Facebook and using the privacy settings less than adults. Despite these differences, the results indicated that adolescents and adults were more similar than different in the factors that predicted information disclosure and control. Adolescents spent more time on Facebook, which partially mediated the relationship between group (adolescents vs. adults) and disclosure. Self-esteem partially mediated the relationship between group and information control, with adults having higher self-esteem than adolescents.
Social Exchange at Work and Emotional Exhaustion: The Role of Personality

Unbalanced social-exchange processes at work have been linked to emotional exhaustion. In addition to organizational factors, individual differences are important determinants of reciprocity perceptions. This study explored whether broad and narrow personality traits were associated with perceived lack of reciprocity (organizational and interpersonal levels), and whether personality moderated the relationship between reciprocity and emotional exhaustion, in a sample of 322 civil servants. Extraversion, agreeableness, emotional stability, internal locus of control, and Type A behavior predicted reciprocity. The relationship between perceived lack of reciprocity with the organization and emotional exhaustion was stronger for individuals reporting lower negative affect or higher extraversion. These findings highlight the importance of personality for understanding perceived reciprocity at work and its impact on emotional exhaustion. jasp_812 2165.2199
Acetylcholine activates non‐selective cation and chloride conductances in canine and guinea‐pig tracheal myocytes.

1. Membrane currents activated by acetylcholine (ACh) were investigated in isolated canine and guinea‐pig tracheal myocytes using the nystatin perforated patch configuration of whole‐cell recording. ACh caused depolarization accompanied by a membrane conductance increase. 2. When cells were held under voltage clamp (holding potential, Vh = ‐60 mV), ACh elicited inward current (IACh) of up to 3900 pA, with a reversal potential (Erev) of approximately ‐20 mV. 3. Removal of extracellular Na+ (Na+o) reduced but did not eliminate IACh. IACh remaining in the absence of Na+ reversed direction close to the predicted equilibrium potential for Cl‐. Erev shifted 32 +/‐ 4 mV per 10‐fold change of [Cl‐]i. Increasing external [K+] caused Erev to shift in the positive direction. These results suggest that ACh activated chloride and non‐selective cation conductances. 4. In the absence of Na+o, the Cl‐ channel blockers SITS or niflumic acid reversibly antagonized IACh. 5. Caffeine and ryanodine elicited currents both in the presence and absence of Na+o; these currents had a reversal potential similar to that of IACh. Caffeine applied before ACh occluded the response to ACh. 6. We also observed two types of spontaneous membrane currents. Spontaneous transient outward currents (STOCs) may represent Ca(2+)‐activated K+ currents. Spontaneous inward currents were also observed which were reduced in magnitude (but not eliminated) by removal of Na+o and reversed direction at approximately the Cl‐ equilibrium potential. The spontaneous inward currents and STOCs were coincident and were reversibly suppressed by ACh. 7. ACh elicited contractions of cells under voltage clamp at ‐60 mV, an effect also observed in the absence of extracellular Ca2+ or when IACh was reduced by omission of Na+o and exposure to Cl‐ channel blockers. The number of cells which did contract in response to ACh decreased, however, when the concentration of internal Cl‐ decreased. 8. All effects of ACh on contraction and membrane currents were antagonized by atropine. 9. We conclude that activation of muscarinic receptors in mammalian tracheal myocytes causes release of Ca2+ from intracellular stores and subsequent activation of Cl‐ and non‐selective cation conductances. This is the first direct demonstration of these conductances in tracheal smooth muscle cells. Activation of these conductances does not appear to be required for contraction. However, regulation of cytosolic Cl‐ levels may be important for release and uptake of Ca2+ from internal stores.
Career Development of Black Males: Case Studies

Black American men are among the nation’s most unemployed and underemployed groups (Leonard, 1985). The unemployment rate among Black Americans was 10.4% in 1995, as compared with 4.9% among White Americans, 9.3% among Hispanics, and 5.6% among all Americans (Table 644 in Bureau of the Census, 1997). In addition to racism (Brown & Ford, 1977), this situation may be partly explained by the educational attainment and vocational choices of Black males. Comparing Black and White men, Karweit (1977) found that Black men tend to have lower educational attainments, terminate formal schooling earlier, resume schooling less often and after a longer absence, and pursue non-degree oriented courses more often. Other studies suggest that Black and White college men have different vocational interests. Black males tend to prefer artistic occupations (Slaney & Brown, 1983) and services to people, whereas White men are more interested in math and science occupations (Hager & Elton, 1971). While math and science related careers tend to require more education and imply higher prestige and financial rewards, these racial differences in educational attainment and vocational choice, together with racial discrimination, may contribute to Black men’s higher rate of unemployment and underemployment and their underrepresentation in occupations with higher socioeconomic status.
Intraventricular Hemorrhage and Post Hemorrhagic Hydrocephalus among Very-Low-Birth-Weight Infants in Korea

Here, we aimed to evaluate the incidence and mortality of intraventricular hemorrhage (IVH) and post-hemorrhagic hydrocephalus (PHH) among very-low-birth-weight (VLBW) infants in Korea and assess the associated factors of PHH. This cohort study used prospectively collected data from the Korean Neonatal Network (KNN). Among 2,386 VLBW infants in the KNN database born between January 2013 and June 2014, 63 infants who died without brain ultrasonography results were excluded. Maternal demographics and neonatal clinical characteristics were assessed. The overall incidence of IVH in all the VLBW infants was 42.2% (987 of 2,323), while those of IVH grade 1, 2, 3, and 4 were 25.1%, 7.0%, 4.8%, and 5.5%, respectively. The incidence and severity of IVH showed a negatively correlating trend with gestational age and birth weight. PHH developed in 0%, 3.5%, 36.1%, and 63.8% of the surviving infants with IVH grades 1, 2, 3, and 4, respectively. Overall, in the VLBW infants, the IVH-associated mortality rate was 1.0% (24/2,323). Only IVH grade severity was proven to be an associated with PHH development in infants with IVH grades 3-4. This is the first Korean national report of IVH and PHH incidences in VLBW infants. Further risk factor analyses or quality improvement studies to reduce IVH are warranted.
The “Sugar Pack” Health Marketing Campaign in Los Angeles County, 2011-2012

As part of a comprehensive approach to combating the obesity epidemic, the Los Angeles County Department of Public Health launched the “Sugar Pack” health marketing campaign in fall 2011. Carried out in three stages, the campaign sought to educate and motivate the public to reduce excess calorie intake from sugar-sweetened beverage consumption. The primary Sugar Pack creative concepts provided consumers with information about the number of sugar packs contained in sugary drinks. Data from formative market research as well as lessons from previous campaigns in other U.S. jurisdictions informed the development of the materials. These materials were disseminated through a multipronged platform that included paid outdoor media on transit and billboards and messaging using social media (i.e., Twitter, Facebook, YouTube, and sendable e-cards). Initial findings from a postcampaign assessment indicate that the Sugar Pack campaign reached broadly into targeted communities, resulting in more than 515 million impressions. Lessons learned from the campaign suggest that employing health marketing to engage the public can lead to increased knowledge, favorable recognition of health messages, and self-reported intention to reduce sugar-sweetened beverage consumption, potentially complementing other obesity prevention strategies in the field.
When Do Warmth and Competence Sell Best? The “Golden Quadrant” Shifts as a Function of Congruity With the Product Type, Targets’ Individual Differences, and Advertising Appeal Type

Three experiments reported here uniquely test the effectiveness of warm versus competent advertising strategy as a function of congruence with other elements of the advertising context. These are product involvement (Experiment 1, n = 96), consumers’ smartphone anxiety (Experiment 2, n = 60), or self-versus other-profitability (Experiment 3, n = 100). As expected, the “golden quadrant” (optimum warmth and competence for advertising effectiveness) does shift: Competence is more important for high-involving products, but warmth wins for highly anxious participants or when the highly involving service is accompanied by people-focused appeals. An expansion of the stereotype content model is discussed in the context of the congruity principle.
Evidence that anticipated stigma predicts poorer depressive symptom trajectories among emerging adults living with concealable stigmatized identities

Abstract People living with concealable stigmatized identities are vulnerable to experiencing greater depressive symptoms as a result of occupying a lower social status. In the present research, we examine the effect of changes in enacted stigma and changes in anticipated stigma on trajectories of depressive symptoms over time. A sample of 192 college-aged emerging adults (81.0% female, 81.9% Caucasian, Mage = 18.82 years) living with a concealable stigmatized identity (e.g., mental illness and sexual minority status) completed measures of enacted stigma, anticipated stigma, and depressive symptoms at two time points across eight weeks. Hierarchical linear modeling analyses indicate that increases in anticipated stigma, but not enacted stigma, predicted poorer trajectories of depressive symptoms, controlling for the effect of baseline rumination and other identity-related variables. These data are among the first to demonstrate that worries about future devaluation predict poorer depressive symptom trajectories over time among college-aged emerging adults.
Human papillomavirus type 6b DNA required for initiation but not maintenance of transformation of C127 mouse cells

We describe the transformation of C127 mouse fibroblasts with human papillomavirus type 6b (HPV-6b) DNA, which is associated primarily with benign tumors of the human genital tract. The major transformed phenotype of the HPV-6b-transfected cells lines, which had been G418 selected, pooled, and maintained without subsequent selection, was tumorigenicity in nude mice. We found that, unlike that reported for other HPVs or papovaviruses, the transformed phenotype was expressed after a delay, in which the cells had undergone extensive culture passages (about 20 passages or 100 generations). Interestingly, the HPV-6b DNA had become reduced or nondetectable in copy number in the cells by the time the transformed phenotype was expressed and in most of the tumors induced by the cells in nude mice, indicating that high levels of HPV-6b DNA were not required for maintenance of the transformed phenotype. Clonal cell lines gave similar results. When continued G418 selection was used to maintain high-copy-number HPV-6b DNA, the cells were tumorigenic, indicating that high levels of HPV-6b DNA did not suppress tumorigenesis. These studies suggest that HPV-6b DNA initiates transformation of C127 cells but is dispensable for expression or maintenance of the transformed phenotype. Transformation by HPV-6b DNA in vitro may provide insights into the HPV type-specific association with benign versus malignant lesions in vivo and may elucidate some of the oncogenic processes involved in tumor progression.
The Neurite Outgrowth Inhibitory Nogo-A-Δ20 Region Is an Intrinsically Disordered Segment Harbouring Three Stretches with Helical Propensity

Functional recovery from central neurotrauma, such as spinal cord injury, is limited by myelin-associated inhibitory proteins. The most prominent example, Nogo-A, imposes an inhibitory cue for nerve fibre growth via two independent domains: Nogo-A-Δ20 (residues 544–725 of the rat Nogo-A sequence) and Nogo-66 (residues 1026–1091). Inhibitory signalling from these domains causes a collapse of the neuronal growth cone via individual receptor complexes, centred around sphingosine 1-phosphate receptor 2 (S1PR2) for Nogo-A-Δ20 and Nogo receptor 1 (NgR1) for Nogo-66. Whereas the helical conformation of Nogo-66 has been studied extensively, only little structural information is available for the Nogo-A-Δ20 region. We used nuclear magnetic resonance (NMR) spectroscopy to assess potential residual structural propensities of the intrinsically disordered Nogo-A-Δ20. Using triple resonance experiments, we were able to assign 94% of the non-proline backbone residues. While secondary structure analysis and relaxation measurements highlighted the intrinsically disordered character of Nogo-A-Δ20, three stretches comprising residues 561EAIQESL567, 639EAMNVALKALGT650, and 693SNYSEIAK700 form transient α-helical structures. Interestingly, 561EAIQESL567 is situated directly adjacent to one of the most conserved regions of Nogo-A-Δ20 that contains a binding motif for β1-integrin. Likewise, 639EAMNVALKALGT650 partially overlaps with the epitope recognized by 11C7, a Nogo-A-neutralizing antibody that promotes functional recovery from spinal cord injury. Diffusion measurements by pulse-field gradient NMR spectroscopy suggest concentration- and oxidation state-dependent dimerisation of Nogo-A-Δ20. Surprisingly, NMR and isothermal titration calorimetry (ITC) data could not validate previously shown binding of extracellular loops of S1PR2 to Nogo-A-Δ20.
Sources of Perceived Self-Efficacy as Predictors of Physical Activity in Older Adults

According to Bandura's self-efficacy theory, there are four sources of self-efficacy: past experience, vicarious experience, verbal persuasion, and perception of physical states. The aims of the study were twofold: To review previous research on the sources of self-efficacy and to examine the sources in predicting self-efficacy for exercise in older adults. A sample of 309 older adults was assessed at two time points for exercise, exercise-specific self-efficacy, and four sources of self-efficacy. Past experiences, vicarious experiences, and subjective health had significant direct effects on self-efficacy and indirect effects on exercise via self-efficacy. Persuasive arguments did not predict self-efficacy. This suggests that future research should target past experience and vicarious experience as sources of self-efficacy.
Job Characteristics, Employee Voice and Well-Being in Britain

Job characteristics are often omitted when analysing job satisfaction, but these are crucial to work psychology models, such as the Karasek model. There has also been a neglect of non-union voice. This study uses data from the 2004 Workplace Employee Relations Survey to investigate the associations between job characteristics and employee voice and well-being. Improvements in the survey from that of 1998 mean that we can examine two dimensions of well-being: job satisfaction and the less studied anxiety–contentment. Support is found for the basic Karasek model that both measures of well-being are negatively related to job demands and positively related to job control; moreover, high job controls reduce the negative association between job demands and both measures. Supportive management is also related to both measures but does not play the buffering role between demands and well-being that job control does. Union membership is found to be unrelated to job satisfaction and anxiety–contentment, but a perception of consultative management is.
Country of origin, encounter norms, and crowding in a frontcountry setting

Existing normative studies have focused on backcountry encounter norms reported by North Americans. This study compares encounter norms and perceptions of crowding reported by visitors from five different countries of origin—Canada, United States, Japan, Germany, and England—to a frontcountry day‐use recreation area. Data were obtained from random samples of two types of visitors—those riding in “snocoach” tour vehicles (n = 463) and those on the toe of the glacier (n = 375)—at the Columbia Icefield in Jasper National Park, Alberta. Results indicated both similarities and differences among the visitors. In terms of differences, Anglo American respondents were least likely to specify a norm, while the Germans and Japanese were most likely. Among those who reported an encounter norm, however, the average tolerance limit did not vary by country of origin. Few differences were also apparent for perceived crowding levels among the five visitor groups. Irrespective of country of origin, when contacts exceeded t.
“It Was Like a Revolution”

In 1997, a multinational company in northern Mexico replaced a work policy that required women to quit on marriage or pregnancy. Analysis of extensive data from a qualitative case study shows how the women perceive the policy change as shaping work–family choices. The women interpret the change as significant because it recognizes women’s “right to work” and grants them access to family-friendly workplace policies. But their interpretations of how it plays out in practice vary over the gendered life course. Furthermore, evidence of obstacles to women’s advancement indicates that workplace practices remain gendered and vary by occupational status and age. This analysis demonstrates the importance of situating women’s workplace experiences within a particular context with its distinct cultural and sociopolitical framings of work and family.
Diabetes Mellitus Impact on Periodontal Status in Children and Adolescents

Diabetes mellitus is a systemic disease with several major complications affecting both the quality and length of life. One of these complications is periodontal disease. Periodontal disease (periodontitis) is much more than a localized oral infection, recent data indicating that periodontitis may cause changes in systemic physiology. The interrelationships between periodontitis and diabetes provide an example of systemic disease predisposing to oral infection, and once that infection is established, the oral infection exacerbates systemic disease. The relationship between periodontitis and diabetes has been extensively investigated over the last years, but despite of the numerous scientific studies on the influence of periodontal treatments on glycemic control, there is limited knowledge on the impact of glycemic control upon periodontal status. Moreover, the impact of periodontal treatment on sugar metabolic control in diabetics has not been fully elucidated, the present chapter intending an outlining of the features that governs the interrelationship diabetes mellitus – periodontal disease, a discussion of the present scientific evidences, mainly focusing on clinic-biological research in juvenile groups of population.
Tying the King's Hands

Historians commonly assume that the Old Regime monarchy in France attempted to eliminate corporate society in order to create liberal institutions. They also assume that the centralization of state power occurred at the expense of such corporate bodies as provincial estates, the municipal corporations, and the village communities. By contrast, I argue that those institutions were not vestiges of an earlier society waiting to be swept away by the stronger, more unified modern state. Instead, I believe that corporate bodies not only flourished under the Old Regime, but contributed to the functioning of the absolute state.
Pathogenic Strains of Yersinia enterocolitica Isolated from Domestic Dogs (Canis familiaris) Belonging to Farmers Are of the Same Subtype as Pathogenic Y. enterocolitica Strains Isolated from Humans and May Be a Source of Human Infection in Jiangsu Province, China

ABSTRACT We isolated 326 Yersinia enterocolitica strains from 5,919 specimens from patients with diarrhea at outpatient clinics, livestock, poultry, wild animals, insect vectors, food, and the environment in the cities of Nantong and Xuzhou in Jiangsu Province, China, from 2004 to 2008. The results showed that the 12 pathogenic strains were of the O:3 serotype. Six strains were isolated from domestic dogs (Canis familiaris) belonging to farmers and were found to be the primary carriers of pathogenic Y. enterocolitica strains, especially in Xuzhou. Pulsed-field gel electrophoresis analysis of the pathogenic strains from dogs belonging to farmers showed that they shared the same patterns as strains from diarrhea patients isolated in 1994. This indicates that the strains from domestic dogs have a close correlation with the strains causing human infections.
Effortful Control and Impulsivity as Concurrent and Longitudinal Predictors of Academic Achievement

The goal of this study was to test if both effortful control (EC) and impulsivity, a reactive index of temperament, uniquely predict adolescents’ academic achievement, concurrently and longitudinally (Time 1: N = 168, x ¯ age = 12 years). At Time 1, parents and teachers reported on students’ EC and impulsivity. At both time points, spaced 2 years apart, parents and teachers reported on students’ achievement. In a concurrent regression, both EC and impulsivity were positively related to achievement. At T1, there was evidence of a nonlinear relation between impulsivity and achievement, and the shape of the quadratic was dependent on if EC was simultaneously considered. Results from a longitudinal analysis demonstrated that although parent-reported impulsivity was generally negatively correlated with achievement, EC, but not impulsivity, was prospectively, uniquely related to achievement. The discussion highlights the value of considering adolescents’ EC and impulsivity in models of school success.