Miracle-dz/UniFAR-FTUs huggingface dataset:
Nanofibrillated Cellulose Surface Modification: A Review

Interest in nanofibrillated cellulose (NFC) has increased notably over recent decades. This bio-based nanomaterial has been used essentially in bionanocomposites or in paper thanks to its high mechanical reinforcement ability or barrier property respectively. Its nano-scale dimensions and its capacity to form a strong entangled nanoporous network have encouraged the emergence of new high-value applications. It is worth noting that chemical surface modification of this material can be a key factor to achieve a better compatibility with matrices. In order to increase the compatibility in different matrices or to add new functions, surface chemical modification of NFC appears to be the prior choice to conserve its intrinsic nanofibre properties. In this review, the authors have proposed for the first time an overview of all chemical grafting strategies used to date on nanofibrillated cellulose with focus on surface modification such as physical adsorption, molecular grafting or polymer grafting.
Review of Macroinvertebrate Drift in Lotic Ecosystems

1 Stream ecologists have incorporated the landscape perspective for several decades when conducting ecological work in streams. Although macroinvertebrate drift has been studied for more than five decades in lotic systems, it has not sufficiently been incorporated into the modern stream ecology or ecotone ecology and instituted on a landscape level of investigation. An early review of drift of stream insects emphasized that there is not a distinct drift fauna. Rather it is the benthic community that participates in the drift due to many biotic and abiotic factors. Furthermore, spatial and temporal scales of drift vary considerably between stream systems and seasons (Table 1). Other reviews of the literature have been conducted typically with some limitation in time covered or subjects, concentrating on the underlying mechanisms behind drift. In several reviews on the effects of flow on benthic organisms drift was viewed purely as a mechanism of dispersal. Interestingly, they stated that little is known about the biological processes involved in water column entry (besides accidental drift), instream transport, and settlement. In particular, what are the key principles behind settlement of drifting individuals. In the past half century, most studies on stream drift have concentrated on the underlying biotic and abiotic processes (Fig. 1) involved in drift. It has even been suggested that drift be used as a standard component of bioassessment because it provides complimentary information to traditional benthic sampling. One of the most studied properties of drift is its diel periodicity. Investigations in tropical, subtropical, and temperate regions have shown that drift displays distinct circadian patterns. 2 Several studies have used drift to improve the understanding of life histories of Trichoptera communities in a wide range of biomes to include streams from Oregon, Denmark, Pyrénées, and Laurentia. One study from Scotland used drift as a metric for evaluating colonization
A Full Lifecycle Bioenergetic Model for Bluefin Tuna

We formulated a full lifecycle bioenergetic model for bluefin tuna relying on the principles of Dynamic Energy Budget theory. Traditional bioenergetic models in fish research deduce energy input and utilization from observed growth and reproduction. In contrast, our model predicts growth and reproduction from food availability and temperature in the environment. We calibrated the model to emulate physiological characteristics of Pacific bluefin tuna (Thunnus orientalis, hereafter PBT), a species which has received considerable scientific attention due to its high economic value. Computer simulations suggest that (i) the main cause of different growth rates between cultivated and wild PBT is the difference in average body temperature of approximately 6.5°C, (ii) a well-fed PBT individual can spawn an average number of 9 batches per spawning season, (iii) food abundance experienced by wild PBT is rather constant and sufficiently high to provide energy for yearly reproductive cycle, (iv) energy in reserve is exceptionally small, causing the weight-length relationship of cultivated and wild PBT to be practically indistinguishable and suggesting that these fish are poorly equipped to deal with starvation, (v) accelerated growth rate of PBT larvae is connected to morphological changes prior to metamorphosis, while (vi) deceleration of growth rate in the early juvenile stage is related to efficiency of internal heat production. Based on these results, we discuss a number of physiological and ecological traits of PBT, including the reasons for high Feed Conversion Ratio recorded in bluefin tuna aquaculture.
Insights into the Performance of Magnetoelectric Ceramic Layered Composites

Finite element analysis is used to simulate the magnetoelectric response of magnetostrictive-piezoelectric NiFe2O4-Bi0.36Pb0. 64Sc0.36Ti0. 64O3 ceramic two-layer, three-layer, and multilayer structures considering finite geometry and introducing the conductivity of the magnetic component. Results are compared with those obtained with existing approximate analytical solutions, and with the experimental data available for high-quality layered composites. Limitations of the widely used analytical solution for a bilayer are revealed, and the reported good agreement with experimental coefficients is shown to be coincidental. Magnetoelectric coefficients obtained by simulation using realistic material parameters are systematically above the experimental values for three-layer and multilayer composites. Possible mechanisms for the reduction in response are analyzed. Strain relaxation across the piezoelectric layer, strongly associated with its mechanical performance, is shown to be the most feasible cause.
Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum.

Verticillium longisporum is a soil-borne vascular pathogen causing economic loss in rape. Using the model plant Arabidopsis this study analyzed metabolic changes upon fungal infection in order to identify possible defense strategies of Brassicaceae against this fungus. Metabolite fingerprinting identified infection-induced metabolites derived from the phenylpropanoid pathway. Targeted analysis confirmed the accumulation of sinapoyl glucosides, coniferin, syringin and lignans in leaves from early stages of infection on. At later stages, the amounts of amino acids increased. To test the contribution of the phenylpropanoid pathway, mutants in the pathway were analyzed. The sinapate-deficient mutant fah1-2 showed stronger infection symptoms than wild-type plants, which is most likely due to the lack of sinapoyl esters. Moreover, the coniferin accumulating transgenic plant UGT72E2-OE was less susceptible. Consistently, sinapoyl glucose, coniferyl alcohol and coniferin inhibited fungal growth and melanization in vitro, whereas sinapyl alcohol and syringin did not. The amount of lignin was not significantly altered supporting the notion that soluble derivatives of the phenylpropanoid pathway contribute to defense. These data show that soluble phenylpropanoids are important for the defense response of Arabidopsis against V. longisporum and that metabolite fingerprinting is a valuable tool to identify infection-relevant metabolic markers.
Bone marrow mesenchymal stem cell transplantation improves ovarian function and structure in rats with chemotherapy-induced ovarian damage.

BACKGROUND Many investigations have reported that mesenchymal stem cell (MSC) transplantation can ameliorate the structure and function of injured tissues. The purpose of this study was to explore the therapeutic potency of MSC transplantation for chemotherapy-induced ovarian damage. METHODS MSC were isolated and cultured in vitro. The cytokines, including vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF) and insulin-like growth factor-1 (IGF-1), were detected in the MSC cultures using enzyme-linked immunosorbent assay (ELISA). Phosphoramide mustard (PM) was added to the media of granulosa cells (GC) cultured alone or co-cultured with MSC. GC apoptosis was assayed by Annexin-V and DNA fragmentation analysis. Chemotherapy-induced ovarian damage was induced in rats by intraperitoneal injection of cyclophosphamide (CTX). After the injection, MSC labeled with green fluorescent protein (GFP) were transplanted directly into bilateral ovaries. The rats were killed at 2, 4, 6 and 8 weeks after transplantation. Ovarian function was evaluated by estrous cycle changes and sexual hormone levels. The follicle number was counted, and GC apoptosis was analyzed by TUNEL. The expressions of Bcl-2 and Bax proteins were detected by Western blotting. RESULTS MSC released VEGF, HGF and IGF-1 in vitro. The GC apoptosis was diminished by co-culture with MSC, which also resulted in increased Bcl-2 expression. The ovarian function of the rats exposed to CTX injection was improved after MSC transplantation. MSC reduced apoptosis of GC and induced up-regulation of Bcl-2 in vivo. DISCUSSION MSC transplantation can improve ovarian function and structure damaged by chemotherapy. The paracrine mediators secreted by MSC might be involved in the repair of damaged ovaries.
Thermogravimetric analysis of combustion characteristics and kinetics of hydrothermally treated and washed empty fruit bunch

Abstract This study aims to study the fuel properties, combustion behaviors and kinetics of hydrothermally treated and washed empty fruit bunch (HTW-EFB). For the lab-scale samples, EFB was hydrothermally treated (HT) at 180, 200 or 220 °C for 30 min and washed using water at 60 °C for 15 min to remove alkaline metals. For the commercial-scale sample, EFB was HT at 2 MPa for 30 min and washed with room temperature water using a centrifugal machine. Results indicate that a combination of hydrothermal and washing treatments (HTW) improved fuel properties of EFB significantly, with an increase in calorific value to 2.33 × 104 kJ kg−1 and a reduction in the alkaline contents. Significant shifts in combustion behavior were observed when EFB underwent HTW. The ignition temperature of the hydrochars was 290–296 °C with the burnout temperature at 438–485 °C. From the kinetic study, a first-order reaction and one-dimensional diffusion is the main mechanism in the combustion of volatiles, while one-dimensional diffusion is the main mechanism for the combustion of the fixed carbon of the hydrochars. The activation energy of HTW-EFBs was between 99.96 and 138.26 kJ mol−1 in the devolatilization stage and 10.97–27.56 kJ mol−1 in the char oxidation stage.
Funnel libraries for real-time robust feedback motion planning

We consider the problem of generating motion plans for a robot that are guaranteed to succeed despite uncertainty in the environment, parametric model uncertainty, and disturbances. Furthermore, we consider scenarios where these plans must be generated in real time, because constraints such as obstacles in the environment may not be known until they are perceived (with a noisy sensor) at runtime. Our approach is to pre-compute a library of “funnels” along different maneuvers of the system that the state is guaranteed to remain within (despite bounded disturbances) when the feedback controller corresponding to the maneuver is executed. We leverage powerful computational machinery from convex optimization (sums-of-squares programming in particular) to compute these funnels. The resulting funnel library is then used to sequentially compose motion plans at runtime while ensuring the safety of the robot. A major advantage of the work presented here is that by explicitly taking into account the effect of uncertainty, the robot can evaluate motion plans based on how vulnerable they are to disturbances. We demonstrate and validate our method using extensive hardware experiments on a small fixed-wing airplane avoiding obstacles at high speed (~12 mph), along with thorough simulation experiments of ground vehicle and quadrotor models navigating through cluttered environments. To our knowledge, these demonstrations constitute one of the first examples of provably safe and robust control for robotic systems with complex nonlinear dynamics that need to plan in real time in environments with complex geometric constraints.
Molar incisor hypomineralization. Morphological and chemical aspects, onset and possible etiological factors.

UNLABELLED OVERALL AIM: The general objective of this thesis was to enhance the understanding of Molar Incisor Hypomineralization (MIH) in areas of the histological, chemical and mechanical properties of the hypomineralized enamel, objective and subjective clinical symptoms in relation to bacteria findings. Further, to estimate a time for onset of the disturbance and investigate possible etiological factors. MATERIAL & METHODS 22 teeth diagnosed with MIH were used in the histological and chemical studies. A number of analytical methods were used; Light microscopy, Polarized light microscopy, Scanning electron microscopy, X-ray microanalysis, Vickers hardness test and X-ray Micro Computed Tomography. Decalcified sections were stained with bacterial staining. An ozone device was tested for the ability to kill strains of oral bacteria. In collaboration with the prospective ABIS study, 17.000 individuals were examined and possible etiological causes of severe demarcated opacities were tested. RESULTS & CONCLUSIONS The hypomineralized enamel was mainly located in the buccal enamel of the teeth and had a high degree of porosity extending from enamel-dentin-junction with a distinct border to the normal cervical enamel. Teeth diagnosed MIH had lower hardness values in hypomineralized enamel and differences in the chemical composition. Bacteria were observed in the enamel and deep into the dentin. Ozone treatment for 20 seconds or more was effective to kill oral microorganisms. Significant relations were found between MIH in first molars and breast feeding more than 6 months, late introduction to gruel and infant formula (later than 6 months). The onset for the hypomineralized enamel was estimated to around 200 days from start of the enamel mineralization.
Melanoma Cells Can Adopt the Phenotype of Stromal Fibroblasts and Macrophages by Spontaneous Cell Fusion in Vitro

After the removal of primary cutaneous melanoma some patients develop local recurrences, even after having histologically tumor-free re-excision. A potential explanation behind this phenomenon is that tumor cells switch their phenotype, making their recognition via standard histopathological assessments extremely difficult. Tumor-stromal cell fusion has been proposed as a potential mechanism for tumor cells to acquire mesenchymal traits; therefore, we hypothesized that melanoma cells could acquire fibroblast- and macrophage-like phenotypes via cell fusion. We show that melanoma cells spontaneously fuse with human dermal fibroblasts and human peripheral blood monocytes in vitro. The hybrid cells’ nuclei contain chromosomes from both parental cells and are indistinguishable from the parental fibroblasts or macrophages based on their morphology and immunophenotype, as they could lose the melanoma specific MART1 marker, but express the fibroblast marker smooth muscle actin or the macrophage marker CD68. Our results suggest that, by spontaneous cell fusion in vitro, tumor cells can adopt the morphology and immunophenotype of stromal cells while still carrying oncogenic, tumor-derived genetic information. Therefore, melanoma–stromal cell fusion might play a role in missing tumor cells by routine histopathological assessments.
Sensing-based interaction for information navigation on handheld displays

Information navigation on handheld displays is characterized by the small display dimensions and limited input capabilities of today's mobile devices. Special strategies are required to help users navigate to off-screen content and develop awareness of spatial layouts despite the small display. On the other hand, handheld devices offer interaction possibilities that desktop computers do not. Handheld devices can easily be moved in space and used as a movable window into a large virtual workspace. We investigate different information navigation methods for small-scale handheld displays using a range of sensor technologies for spatial tracking. We compare user performance in an map navigation task and discuss the tradeoffs of the different sensor and visualization techniques.
18 F-FDG PET / CT and Melanoma Value of Fourth and Subsequent Posttherapy Follow-up Scans for Patient Management

Purpose: We aimed to evaluate the added value of performing fourth and subsequent follow-up F-FDG-PET/CT scans to clinical assessment and impact on the patient’s management in patients with melanoma. Methods: This was a retrospective study of 232 biopsy-proven melanoma patients who underwent 18F-FDG-PET/CT scans. Of these, 71 patients had 4 or more follow-up F-FDG-PET/CT scans after completion of primary treatment, with a total of 246 fourth or subsequent follow-up PET/CT scans. The added value of each follow-up PET/CT scan to the patient’s clinical assessment and treatment management was established. Kaplan-Meier plots with a Mantel-Cox log-rank test were used to establish the patient’s overall survival. Results: Of the 246 fourth and subsequent follow-up PET/CT scans, 61% (150/246) were negative for malignancy, and 39.0% (96/246) were positive for recurrence/metastases. FDG-PET/CTwas helpful in identifying malignancy in 6.5% of the scans performed without prior clinical suspicion, which ruled out malignancy in 28.5% of the scans obtained with prior clinical signs suggestive of recurrence or for secondary therapy assessment. The PET/CT scan resulted in change of the patient’s management in approximately 16.7% (41/246) of the scans. Change in management was significantly greater in patients whose scans were done with prior clinical signs suggestive of malignancy, or for therapy assessment than without prior clinical suspicion (29.3% vs 4.1%; P < 0.0001). Statistically significant difference was seen in the overall survival between patients with at least 1 positive and all negative fourth and subsequent follow-up PET/CT scans at patient level (P = 0.001). Conclusions: The fourth and subsequent F-FDG-PET/CT scans obtained after completion of primary treatment added value to clinical assessment in patients with melanoma. Patients with clinical signs suggestive of recurrence or metastases or being monitored for treatment response are more likely to benefit from the fourth or subsequent FDG PET/CT than those without prior clinical suspicion.
Detecting hybridization of DNA by highly sensitive evanescent field etched core fiber Bragg grating sensors

Highly sensitive fiber Bragg grating sensors were developed by etching away the cladding and part of the core of the fiber and detecting the change of Bragg wavelength due to the change of index of the surrounding medium. A sensitivity of 1394 nm/riu was achieved when the diameter of the grating core was 3.4 /spl mu/m and the index of the surrounding medium was close to the index of the core of the fiber. Assuming a detectable spectral resolution of 0.01 nm realized in the experiment, the sensor achieves a minimum detectable index resolution of 7.2/spl times/10/sup -6/. Higher sensitivity at lower surrounding index was achieved by using higher order modes excited in the Bragg grating region. The use of the fiber Bragg grating sensor was further investigated to detect hybridization of DNA. Single stranded DNA oligonucleotide probes of 20 bases were immobilized on the surface of the fiber grating using relatively common glutarahyldehyde chemistry. Hybridization of complimentary target single strand DNA oligonucleotide was monitored in situ and successfully detected. The demonstrated fiber Bragg grating sensors provide an elegant method to monitor biological changes in an in situ manner, and provide temporal information in a single experiment.
A ciphertext-policy attribute-based encryption scheme with constant ciphertext length

An Attribute-Based Encryption (ABE) is an encryption scheme, where users with some attributes can decrypt ciphertexts associated with these attributes. However, the length of the ciphertext depends on the number of attributes in previous ABE schemes. In this paper, we propose a new Ciphertext-Policy Attribute-Based Encryption (CP-ABE) with constant ciphertext length. Moreover, the number of pairing computations is also constant.
Characterisation of invasive clinical Haemophilus influenzae isolates in Queensland, Australia using whole-genome sequencing

SUMMARY Haemophilus influenzae is an important aetiological organism of both adult and child respiratory disease. The number of non-typeable (NTHi) invasive H. influenzae isolates referred to the Queensland (QLD) Public Health Microbiology laboratory has increased notably year-by-year. In this study we used whole-genome sequencing to molecularly characterise 100 referred invasive H. influenzae, including 74 NTHi isolates over a 15-year period, observing the carriage of capsular and putative virulence genes, including the major adhesins, antimicrobial resistance genes and population diversity. Encapsulated isolates were largely clonal, however NTHi isolates displayed high genetic variability by MLST and single nucleotide polymorphism typing with no dominant clone observed. The only mechanism for β-lactam resistance identified in the QLD isolates was β-lactamase production. No single set of virulence determinants was conclusively associated with invasive QLD NTHi isolates.
High-quality Health Information Provision for Stroke Patients

Objective: High-quality information provision can allow stroke patients to effectively participate in healthcare decision-making, better manage the stroke, and make a good recovery. In this study, we reviewed information needs of stroke patients, methods for providing information to patients, and considerations needed by the information providers. Data Sources: The literature concerning or including information provision for patients with stroke in English was collected from PubMed published from 1990 to 2015. Study Selection: We included all the relevant articles on information provision for stroke patients in English, with no limitation of study design. Results: Stroke is a major public health concern worldwide. High-quality and effective health information provision plays an essential role in helping patients to actively take part in decision-making and healthcare, and empowering them to effectively self-manage their long-standing chronic conditions. Different methods for providing information to patients have their relative merits and suitability, and as a result, the effective strategies taken by health professionals may include providing high-quality information, meeting patients’ individual needs, using suitable methods in providing information, and maintaining active involvement of patients. Conclusions: It is suggested that to enable stroke patients to access high-quality health information, greater efforts need to be made to ensure patients to receive accurate and current evidence-based information which meets their individual needs. Health professionals should use suitable information delivery methods, and actively involve stroke patients in information provision.