Miracle-dz/UniFAR-FTUs huggingface dataset:
Incidences of pelvic limb fractures in dogs: A survey of 478 cases -

A survey was undertaken to analyse pelvic limb fractures in dogs reported to Radiology Unit of the Madras Veterinary College, from April 2007-May 2009. A total 478 cases of pelvic limb fractures were reviewed in this study. The incidence was highest in young animals (46.02 percent) less than six months of age. Majority of the fractures were recorded in non-descript dogs (47.48 percent). Male dogs were affected more (61.5 percent) than female dogs of all the age groups. Among the various bones of the pelvic limb the incidence was highest in femur (47.48 percent) followed by tibia and fibula (42.67 percent). The occurrence of oblique/transverse fractures were more (44.8 percent) than comminuted (26.8 percent) and avulsion fractures (7.53 percent).
Risk factors and causes of stillbirths among pregnant women in Pakistan

Background Globally 3 million stillbirths occur per year, and Pakistan is ranked 3rd among the countries having the highest burden. Despite being a major public health problem, efforts to reduce this figure are insufficient. Objective The aim of the study was to identify and measure the inequalities in stillbirth associated risk factors, causes and fertility risk behaviors. Methods Data were derived from the Pakistan Demographic and Health Surveys (PDHS) 1990–2013. Inequalities on determinants were evaluated using rate differences and rate ratios; time trends computed with annualized reduction rate (ARR). Results Overall ARR determined for stillbirth was −12.52 percent per annum. The high ARR were recorded for mothers age <20, urban areas, educated mothers and for highest wealth quintile. The relative inequalities were most pronounced for wealth quintiles, education and age of mothers. Stillbirth causes were unexplained antepartum (33%), unexplained intrapartum (21%), intrapartum asphyxia (21%) and antepartum maternal disorders (19%). The high fertility risk behavior was found in mothers with age >34 and birth order >3. Conclusion The study concluded that to achieve gain in child survival, there is need to promote antenatal care, birth spacing, and family planning programs in developing countries.
Space-Charge Conduction in a Copper Phthalocyanine Static Induction Transistor

We have fabricated a static induction transistor structure by using copper phthalocyanine (CuPc) films. Its layerstructure is Au(drain)/CuPc/Al(gate)/CuPc/Au(source)/glass. The source-drain current is controlled by the Al gate bias-voltage when the drain voltage is positive but is almost independent of it when the drain voltage is negative. The current-voltage characteristics are governed by the space-charge-limited conduction which depends on shallow traps. key words: organic static induction transistor, space-charge-
Paleogenetic evidence for a past invasion of Onondaga Lake, New York, by exotic Daphnia curvirostris using mtDNA from dormant eggs

Cladocerans possess traits such as resistant diapausing eggs and rapid parthenogenetic reproduction that make them efficient invaders of new habitats. Nearly all known invasions have been successful, perhaps because failed invasions are difficult to detect. It is possible, however, to identify past failed invasions, by studying the diapausing egg bank. Daphnia ephippia were found in the sediments of Onondaga Lake, New York that could neither be hatched nor identified using egg‐case morphology. Instead, we used sequences of the 12S ribosomal ribonucleic acid (rRNA) gene of mitochondrial deoxyribonucleic acid (mtDNA) extracted from diapausing eggs to identify the unknown Daphnia. We compared these DNA sequences with those generated from morphologically identified Daphnia species collected in Onondaga Lake, and with published sequences for other North American Daphnia species. The invader was identified as Daphnia curvirostris, a Eurasian species that has been only reported once before from North America, in extreme northwestern Canada. The discovery of it in Onondaga Lake signifies a greater than 4,500‐km range extension for this species. On the basis of the sediment ephippial data, D. curvirostris first appeared in the lake about 1952, reached maximum abundance during the period of peak pollution (1950s–1980s), and then essentially disappeared after 1983 when lake water quality improved. As with the finding of another exotic cladoceran, D. exilis, in Onondaga Lake (Hairston et al. 1999a), it is likely that chemical industry activities on the lakeshores were the original source of invading D. curvirostris, that pollution allowed this species to become established in the lake, and that the reduction in pollution ultimately led to its disappearance from the water column.
Rating through Voting: An Iterative Method for Robust Rating

In this paper we introduce an iterative voting algorithm and then use it to obtain a rating method which is very robust against collusion attacks as well as random and biased raters. Unlike the previous iterative methods, our method is not based on comparing submitted evaluations to an approximation of the final rating scores, and it entirely decouples credibility assessment of the cast evaluations from the ranking itself. The convergence of our algorithm relies on the existence of a fixed point of a continuous mapping which is also a stationary point of a constrained optimization objective. We have implemented and tested our rating method using both simulated data as well as real world data. In particular, we have applied our method to movie evaluations obtained from MovieLens and compared our results with IMDb and Rotten Tomatoes movie rating sites. Not only are the ratings provided by our system very close to IMDb rating scores, but when we differ from the IMDb ratings, the direction of such differences is essentially always towards the ratings provided by the critics in Rotten Tomatoes. Our tests demonstrate high efficiency of our method, especially for very large online rating systems, for which trust management is both of the highest importance and one of the most challenging problems.
Testing Lorentz and CPT Invariance with Neutrinos

Neutrino experiments can be considered sensitive tools to test Lorentz and CPT invariance. Taking advantage of the great variety of neutrino experiments, including neutrino oscillations, weak decays, and astrophysical neutrinos, the generic experimental signatures of the breakdown of these fundamental symmetries in the neutrino sector are presented.
Antimicrobial susceptibility of milk bacteria from healthy and drug-treated cow udder

ZDOLEC, N. , V. DOBRANIĆ, I. BUTKOVIĆ, A. KOTURIĆ, I. FILIPOVIĆ, V. MEDVID: Antimicrobial susceptibility of milk bacteria from healthy and drugtreated cow udder. Vet. arhiv 86, 163-172, 2016. ABSTRACT The aim of this study was to evaluate the antimicrobial susceptibility of milk microbiota, considering udder health status and drug treatment history. Composite milk samples were taken aseptically from healthy cows without any signs of mastitis (n = 17) and drug-treated cows with cured mastitis (n = 19). Antimicrobial susceptibility testing was performed for 56 enterococci, 30 Escherichia coli, 24 enterobacteria and 94 staphylococci. Depending on the bacterial group or species, the following antibiotic disks were used: ampicillin, rifampin, chloramphenicol, linezolid, tetracycline, erythromycin, nitrofurantoin, vancomycin, penicillin, trimethoprim, cefoperazone, kanamycin, trimethoprim/sulfamethoxazole, nalidixic acid, ciprofl oxacin, gentamicin, teicoplanin, sulfonamides, levofl oxacin, clindamycin and amoxicillin/clavulanic acid. The occurrence of multiresistant E. coli and staphylococci was signifi cantly higher (P<0.05) in the milk of drug-treated cows. The percentage ratio (drug-treated: healthy udders) of multiresistant E. coli was 56.3:0, enterobacteria 57.14:30 and staphylococci 56.5: 4.8. There was no signifi cant difference (P>0.05) between the prevalence of multiresistant enterococci in the milk of healthy cows and cows with cured mastitis (87.2:73.7). The high prevalence of resistance in enterococci isolated from milk samples of healthy cows could be the result of animal cohabitation and cross-contamination.
The Variant rs1867277 in FOXE1 Gene Confers Thyroid Cancer Susceptibility through the Recruitment of USF1/USF2 Transcription Factors

In order to identify genetic factors related to thyroid cancer susceptibility, we adopted a candidate gene approach. We studied tag- and putative functional SNPs in genes involved in thyroid cell differentiation and proliferation, and in genes found to be differentially expressed in thyroid carcinoma. A total of 768 SNPs in 97 genes were genotyped in a Spanish series of 615 cases and 525 controls, the former comprising the largest collection of patients with this pathology from a single population studied to date. SNPs in an LD block spanning the entire FOXE1 gene showed the strongest evidence of association with papillary thyroid carcinoma susceptibility. This association was validated in a second stage of the study that included an independent Italian series of 482 patients and 532 controls. The strongest association results were observed for rs1867277 (OR[per-allele] = 1.49; 95%CI = 1.30–1.70; P = 5.9×10−9). Functional assays of rs1867277 (NM_004473.3:c.−283G>A) within the FOXE1 5′ UTR suggested that this variant affects FOXE1 transcription. DNA-binding assays demonstrated that, exclusively, the sequence containing the A allele recruited the USF1/USF2 transcription factors, while both alleles formed a complex in which DREAM/CREB/αCREM participated. Transfection studies showed an allele-dependent transcriptional regulation of FOXE1. We propose a FOXE1 regulation model dependent on the rs1867277 genotype, indicating that this SNP is a causal variant in thyroid cancer susceptibility. Our results constitute the first functional explanation for an association identified by a GWAS and thereby elucidate a mechanism of thyroid cancer susceptibility. They also attest to the efficacy of candidate gene approaches in the GWAS era.
Excitatory/inhibitory response types in the cochlear nucleus: relationships to discharge patterns and responses to electrical stimulation of the auditory nerve.

We have studied the response properties of single units in the cochlear nucleus of unanesthetized decerebrate cats. The purpose of the study was to compare the properties of cochlear nucleus units as described in two commonly used classification schemes. Units were first classified according to their receptive-field properties based on the relative prominence of excitatory and inhibitory responses to tones and noise. Units were then classified on the basis of their discharge patterns to short tone bursts at their best frequencies (BFs). Our results show that systematic relationships exist between the receptive-field properties and discharge patterns of cochlear nucleus units. Type I units give only excitatory responses to tones and noise. They are characterized by primary-like and chopper discharge patterns. Some units in the anteroventral cochlear nucleus have prepotentials in their spike waveforms. Prepotential units most often show primary-like discharge patterns, but prepotential units characterized by nonprimary-like discharge patterns are also found. Most prepotential units lack detectable inhibitory sidebands (type I), but two of the nonprimary-like prepotential units encountered in this study had inhibitory sidebands (type III). Type III units also give excitatory responses to BF tones, but they have inhibitory sidebands. Most type III units give chopper discharge patterns, and these units can be recorded throughout the cochlear nucleus. Some type III units in the dorsal cochlear nucleus give complex discharge patterns that can be described as a composite of the pauser pattern and other patterns. The complexity of these responses seems to increase as the amount of inhibition at BF increases. Type I/III units give excitatory responses to tones and noise, but have little or no spontaneous activity so they cannot be tested directly for inhibitory responses. Type I/III units typically show chopper discharge patterns. One group of type I/III units have rate-level functions with sloping saturation, suggesting that these may receive a predominance of input from low spontaneous rate auditory nerve fibers. Type II units are nonspontaneous and give excitatory responses to tones, but give weak or no responses to noise. While type II units are homogeneous as a group in terms of their response maps. BF rate-level functions, and responses to noise, they show a variety of discharge patterns in response to short tone bursts at BF. (ABSTRACT TRUNCATED AT 400 WORDS)
Transcriptome Analysis of Human Diabetic Kidney Disease

OBJECTIVE Diabetic kidney disease (DKD) is the single leading cause of kidney failure in the U.S., for which a cure has not yet been found. The aim of our study was to provide an unbiased catalog of gene-expression changes in human diabetic kidney biopsy samples. RESEARCH DESIGN AND METHODS Affymetrix expression arrays were used to identify differentially regulated transcripts in 44 microdissected human kidney samples. DKD samples were significant for their racial diversity and decreased glomerular filtration rate (~25–35 mL/min). Stringent statistical analysis, using the Benjamini-Hochberg corrected two-tailed t test, was used to identify differentially expressed transcripts in control and diseased glomeruli and tubuli. Two different web-based algorithms were used to define differentially regulated pathways. RESULTS We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli, and 330 probesets were commonly differentially expressed in both compartments. Pathway analysis highlighted the regulation of Ras homolog gene family member A, Cdc42, integrin, integrin-linked kinase, and vascular endothelial growth factor signaling in DKD glomeruli. The tubulointerstitial compartment showed strong enrichment for inflammation-related pathways. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomeruli and tubuli and was associated with increased glomerulosclerosis even in a different set of DKD samples. CONCLUSIONS Our studies have cataloged gene-expression regulation and identified multiple novel genes and pathways that may play a role in the pathogenesis of DKD or could serve as biomarkers.
Delayed Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Incidence, and Current Management

Even when chemotherapy-induced nausea and vomiting (CINV) can be effectively controlled in the acute phase, it may still occur in the delayed phase. Identifying at-risk patients is complex and requires consideration of clinical, personal, demographic, and behavioral factors. Delayed CINV has a significant detrimental effect on patients’ daily life and is responsible for significant healthcare resource utilization. Patients who do not experience acute CINV are not necessarily exempt from delayed CINV, and healthcare professionals have been shown to underestimate the incidence of delayed CINV. Failure to protect against CINV during the first cycle of chemotherapy is the most significant independent risk factor for delayed CINV during subsequent cycles. Addition of a neurokinin-1 receptor antagonist to antiemetic prophylactic regimens involving a 5-hydroxytryptamine type 3 receptor antagonist and a corticosteroid helps to ameliorate delayed CINV, particularly vomiting. Netupitant and rolapitant are second-generation neurokinin-1 receptor antagonists that provide effective prophylaxis against delayed chemotherapy-induced vomiting and also have an antinausea benefit. All of the neurokinin-1 receptor antagonists with the exception of rolapitant inhibit or induce cytochrome P450 3A4 (CYP3A4), and a reduced dose of dexamethasone (a CYP3A4 substrate) should be administered with aprepitant or netupitant; by contrast, this is not necessary with rolapitant. Here we review specific challenges associated with delayed CINV, its pathophysiology, epidemiology, treatment, and outcomes relative to acute CINV, and its management within the larger context of overall CINV.
Lexicon-Based Sentiment Analysis for Reviews of Products in Brazilian Portuguese

This paper presents some results on lexicon-based classification of sentiment polarity in web reviews of products written in Brazilian Portuguese. They represent a first step towards a robust opinion miner from reviews of technology products. The evaluation shows the performance of 3 different sentiment lexicons combined with simple strategies. It is also discussed the risk of considering the rating provided by the writers for the purpose of evaluating the algorithms. The results show that the better combination is the version of the algorithm that deals also with negation and intensification and uses the sentiment lexicon Sent ilex. The average F-measure achieved 0.73.
Field Significance Revisited: Spatial Bias Errors in Forecasts as Applied to the Eta Model

Abstract The spatial structure of bias errors in numerical model output is valuable to both model developers and operational forecasters, especially if the field containing the structure itself has statistical significance in the face of naturally occurring spatial correlation. A semiparametric Monte Carlo method, along with a moving blocks bootstrap method is used to determine the field significance of spatial bias errors within spatially correlated error fields. This process can be completely automated, making it an attractive addition to the verification tools already in use. The process demonstrated here results in statistically significant spatial bias error fields at any arbitrary significance level. To demonstrate the technique, 0000 and 1200 UTC runs of the operational Eta Model and the operational Eta Model using the Kain–Fritsch convective parameterization scheme are examined. The resulting fields for forecast errors for geopotential heights and winds at 850, 700, 500, and 250 hPa over a period .
Anisotropic patterned population synchrony in climatic gradients indicates nonlinear climatic forcing

Although climatic forcing has been suspected to be the most common cause of spatial population synchrony owing to the Moran effect, it has proved difficult to disentangle the impact of climate from other possible causes of synchrony based on population survey data. Nonlinear population responses to climatic variation may be a part of this difficulty, but they can also provide an opportunity to highlight the climate impacts through targeted survey designs. In particular, when species distribution ranges encompass consistent spatial gradients in climate (e.g. according to latitude or altitude), such gradients can be strategically included in the spatial design of population surveys as to facilitate comparisons of spatial synchrony patterns across and along the gradient. In that case, we predict that nonlinear impacts of climatic variation on population growth rates will result in anisotropic (direction specific) synchrony patterns in the sense that synchrony will drop faster with distance along the climatic gradient than across it. We provide an empirical case study to exemplify survey design and analyses. Of two sympatric species of geometrids, inhabiting an altitudinal gradient in subarctic birch forest, one (Operophtera brumata L.) showed anisotropic synchrony consistent with a strongly nonlinear sensitivity to climatic variation, whereas the other (Epirrita autumnata Bkh.) did not. These results are interpreted in light of the biological characteristics of the species.
Computational aspects of approval voting and declared-strategy voting

Computational social choice is a relatively new discipline that explores issues at the intersection of social choice theory and computer science. Designing a protocol for collective decision-making is made difficult by the possibility of manipulation through insincere voting. In approval voting systems, voters decide whether to approve or disapprove available alternatives; however, the specific nature of rational approval strategies has not been adequately studied. This research explores aspects of strategy under three different approval systems, from chiefly a computational viewpoint. While traditional voting systems elicit only the outcome of a voter's strategic thinking, a Declared-Strategy Voting (DSV) system accepts such strategies directly and applies them according to the voter's preferences over the available alternatives. Ideally, when rational strategies are employed on behalf of the voters, voters are discouraged from expressing insincere preferences. Approval voting is a natural fit for use with DSV, but, unlike for the common plurality voting system, there is no extant theory regarding the most effective approval strategies in a DSV context. We propose such a theory.
Media use and political learning: Comparing Trump supporters to celebrity candidate voters

ABSTRACT This study examines whether political media use behaviors of voters who supported Donald Trump in the 2016 presidential election align with those of “celebrity candidate voters” portrayed in the literature. The study used a national online survey (N = 1,608) conducted during the 2016 primary, and findings reveal that Trump supporters, more than other voters, are driven by entertainment motivations and follow campaign news using entertainment media: specifically, the video-sharing site YouTube. Although Trump voters are interested in the campaign, their level of political knowledge is lower than other voters, and no one media outlet made a significant contribution to their learning. A comparison group of other voters showed significant knowledge gains from news websites and Twitter. Results for Trump voters are consistent with scholars’ characterization of the celebrity candidate audience, particularly in studies suggesting that celebrity politicians may increase citizens’ engagement through entertainment gratifications rather than by a desire to become informed.
Parent–Adolescent Communication and Problematic Internet Use: The Mediating Role of Fear of Missing Out (FoMO)

With the growing attention paid to the role of Fear of Missing Out (FoMO) as a mediator, linking deficits in psychological needs to Problematic Internet Use (PIU), this study explored the role of FoMO in partially explaining the connection between parent–child communication and the child’s PIU. Data were gathered from 270 participants of whom 45.6% 13- to 15-year-old youth (middle school students), and 54.5% 15.5- to 18-year-old adolescents (high school students). Path analysis results have corroborated the main research hypothesis, according to which positive communication activities of parents, such as listening to their children, trying to understand how they feel and what they think, and creating a positive and supportive atmosphere for discussions, can reduce FoMO experiences among adolescents, which in turn might decrease their PIU. Limitations, conclusions, and directions for further research are discussed.