Miracle-dz/UniFAR-FTUs huggingface dataset:
When environmental factors become stressors: interactive effects of vermetid gastropods and sedimentation on corals

Environmental stressors often interact, but most studies of multiple stressors have focused on combinations of abiotic stressors. Here we examined the potential interaction between a biotic stressor, the vermetid snail Ceraesignum maximum, and an abiotic stressor, high sedimentation, on the growth of reef-building corals. In a field experiment, we subjected juvenile massive Porites corals to four treatments: (i) neither stressor, (ii) sedimentation, (iii) vermetids or (iv) both stressors. Unexpectedly, we found no effect of either stressor in isolation, but a significant decrease in coral growth in the presence of both stressors. Additionally, seven times more sediment remained on corals in the presence (versus absence) of vermetids, likely owing to adhesion of sediments to corals via vermetid mucus. Thus, vermetid snails and high sedimentation can interact to drive deleterious effects on reef-building corals. More generally, our study illustrates that environmental factors can combine to have negative interactive effects even when individual effects are not detectable. Such ‘ecological surprises' may be easily overlooked, leading to environmental degradation that cannot be anticipated through the study of isolated factors.
Effect of litter treatment on broiler performance and certain litter quality parameters.

Litter-Aid, a product consisting primarily of ferrous sulfate but also containing propionic acid and magnesium and copper sulfate was incorporated into litter at three application rates (0, .73, and 1.46 kg/m2) to determine its effects on broiler chicken performance and various aspects of litter quality. In Trial 1, litter treatments were applied to litter used for two previous flocks with a 10-week layout period. In Trial 1, there were 10 replicate pens of 175 birds per treatment. In Trial 2, litter used in Trial 1 was retreated, after a 26-week layout period, at the same application rates as Trial 1 with five replicate pens of 175 birds per treatment. This product in Trial 1 at . 73 kg/m2 and in Trial 2 at 1.46 kg/m2 significantly (P less than .05) increased body weight without affecting feed conversion or mortality. The product did not significantly (P less than .05) affect litter moisture or litter nitrogen levels, but significantly (P less than .05) decreased litter pH. However, even at the application rate of 1.46 kg/m2, litter pH values rose above 8 as the birds reached 7 weeks of age. This product had no effect on bacteria counts and significantly (P less than .05) increased mold counts. These data indicate that Litter-Aid can be used without detrimental effects on broiler performance or litter quality.
Robust Transport Over Networks

We consider transportation over a strongly connected, directed graph. The scheduling amounts to selecting transition probabilities for a discrete-time Markov evolution which is designed to be consistent with initial and final marginal constraints on mass transport. We address the situation where initially the mass is concentrated on certain nodes and needs to be transported over a certain time period to another set of nodes, possibly disjoint from the first. The evolution is selected to be closest to a prior measure on paths in the relative entropy sense–such a construction is known as a Schrödinger bridge between the two given marginals. It may be viewed as an atypical stochastic control problem where the control consists in suitably modifying the prior transition mechanism. The prior can be chosen to incorporate constraints and costs for traversing specific edges of the graph, but it can also be selected to allocate equal probability to all paths of equal length connecting any two nodes (i.e., a uniform distribution on paths). This latter choice for prior transitions relies on the so-called Ruelle-Bowen random walker and gives rise to scheduling that tends to utilize all paths as uniformly as the topology allows. Thus, this Ruelle-Bowen law $({\mathfrak {M}}_{\mathrm {RB}})$ taken as prior, leads to a transportation plan that tends to lessen congestion and ensures a level of robustness. We also show that the distribution ${\mathfrak {M}}_{\mathrm {RB}}$ on paths, which attains the maximum entropy rate for the random walker given by the topological entropy, can itself be obtained as the time-homogeneous solution of a maximum entropy problem for measures on paths (also a Schrödinger bridge problem, albeit with prior that is not a probability measure). Finally we show that the paradigm of Schrödinger bridges as a mechanism for scheduling transport on networks can be adapted to graphs that are not strongly connected, as well as to weighted graphs. In the latter case, our approach may be used to design a transportation plan which effectively compromises between robustness and other criteria such as cost. Indeed, we explicitly provide a robust transportation plan which assigns maximum probability to minimum cost paths and therefore compares favorably with Optimal Mass Transportation strategies.
Learning a Neural-network-based Representation for Open Set Recognition

Open set recognition problems exist in many domains. For example in security, new malware classes emerge regularly; therefore malware classification systems need to identify instances from unknown classes in addition to discriminating between known classes. In this paper we present a neural network based representation for addressing the open set recognition problem. In this representation instances from the same class are close to each other while instances from different classes are further apart, resulting in statistically significant improvement when compared to other approaches on three datasets from two different domains.
The Dopamine Receptor D4 Gene (DRD4) and Financial Risk-Taking: Stimulating and Instrumental Risk-Taking Propensity and Motivation to Engage in Investment Activity

The Dopamine receptor D4 gene (DRD4) has been previously linked to financial risk-taking propensity. Past works demonstrated that individuals with a specific variant of the DRD4 gene (7R+) are more risk-seeking than people without it (7R−). The most prominent explanation for this effect is the fact that 7R+ individuals are less sensitive to dopamine and thus seek more stimulation to generate “normal” dopaminergic activity and feel pleasure. However, results about this relationship have not been conclusive, and some revealed a lack of the relationship. In the current work, we tested if those unclear results might be explained by the motivation that underlies the risk-taking activity; i.e., if people take risks to feel excitement or if they take risk to obtain a specific goal. In our study we tested the differences in risk-taking between 7R+ and 7R− among people who are experienced in financial risk-taking (113 investors) and non-experienced financial decision makers (104 non-investors). We measured risk-taking propensity with the Holt-Laury test and the Stimulating-Instrumental Risk Inventory. Moreover, we asked investors about their motivations for engaging in investment activity. Our study is the next one to report a lack of differences in risk-taking between 7R+ and 7R− individuals. As well, our results did not indicate any differences between the 7R+ and 7R− investors in motivation to engage in investment activity. We only observed that risk-taking propensity was higher among investors than non-investors and this was noticed for all measures. More research is needed to better understand the genetic foundations of risk-taking, which could answer the question about the substantial variation in the domain of risky financial decisions.
Epidemiology and predictors of recurrence of Marjolin’s ulcer: experience from Mansoura Universityxs

INTRODUCTION Marjolin’s ulcer (MU) is an uncommon malignancy occurring on top of old scars. Once thought to be more common in Caucasians, is now detected increasingly in Africa. METHODS This was a retrospective study of patients with MU attending a tertiary centre within Mansoura University (Egypt) from 2004 to 2015. An institutional‐based registry of skin and soft‐tissue malignancies in this period revealed 560 cases, from which there were 26 cases of MU. RESULTS The most common underlying cause of MU was burns (92% of patients), followed by trauma. A predilection towards males was detected. The latent period was 4‐70 (median, 25) years. Recurrence occurred in 12 cases, with multiple recurrences occurring in 5 cases. MU recurrence was noted as early as 3 months and as late as 25 years after surgery. CONCLUSIONS Young patients with MU are at higher risk of recurrence and should be followed up closely. A thorough search for nodal metastasis (especially in those with high‐grade tumours) should be done. Wide local excision and leaving wounds to heal by secondary intention seems to be a viable treatment option.
Explicit Scaffolding Increases Simple Helping in Younger Infants

Infants become increasingly helpful during the second year. We investigated experimentally whether adults’ explicit scaffolding influences this development. Infants (N = 69, 13–18 months old) participated in a series of simple helping tasks. Half of infants received explicit scaffolding (encouragement and praise), whereas the other half did not. Among younger infants (below 15 months), infants who received explicit scaffolding helped twice as often as infants in the control group, and also helped more on several subsequent trials when no scaffolding was provided. As predicted, older infants were not affected by explicit scaffolding. These results demonstrate the influence of social experiences in early helping, but also how the effects of scaffolding may depend on the developmental level of the child. Less explicit forms of scaffolding may be effective when children are older.
Constitutive modeling of nonlinear reversible and irreversible ferromagnetic behaviors and application to multiferroic composites

The coupling of magnetic and mechanical fields due to the constitutive behavior of a material is commonly denoted as magnetostrictive effect. The latter is only observed with large coupling coefficients in ferromagnetic materials, where coupling is caused by the rotation of the domains as a result of magnetic (Joule effect) or mechanical (Villari effect) loads. However, only a few elements (e.g. Fe, Ni, Co, and Mn) and their compositions exhibit such a behavior. In this article, the constitutive modeling of nonlinear ferromagnetic behavior under combined magnetomechanical loading as well as the finite element implementation is presented. Both physically and phenomenologically motivated constitutive models have been developed for the numerical calculation of principally different nonlinear magnetostrictive behaviors. On this basis, magnetization, strain, and stress are predicted, and the resulting effects are analyzed. The phenomenological approach covers reversible nonlinear behavior as it is observed, for example, in cobalt ferrite. Numerical simulations based on the physically motivated model focus on the calculation of hysteresis loops and the prediction of local domain orientations and residual stress going along with the magnetization process. Finally, a model for ferroelectric materials is applied in connection with the physically based ferromagnetic approach, in order to predict magnetoelectric coupling coefficients in multifunctional composite.
The reporting of harms in publications on randomized controlled trials funded by the “Programme Hospitalier de Recherche Clinique,” a French academic funding scheme

Background/aims: Accurate information on harms arising from medical interventions is essential for assessing benefit–risk ratios. Since 2004, there has been an extension of the Consolidated Standards of Reporting Trials statement for reporting harms data in publications on randomized clinical trials. The objective of our study was to assess the quality of this reporting from academic randomized clinical trials on drugs. Methods: We searched for articles on randomized clinical trials funded between 2004 and 2008 by the “Programme Hospitalier de Recherche Clinique. ” We included all published randomized clinical trials that assessed drugs. Harm-related data were extracted and compared with the Consolidated Standards of Reporting Trials Harms extension, and the space in the articles devoted to harms data was measured. Results: In total, 37 randomized clinical trials met the inclusion criteria. The median harm score was 9/18. In 73.0% of the randomized clinical trials, the reporting of adverse events was selective. Less than 50% of articles provided information on reasons for drug discontinuation that were related to adverse events. The score and the space allocated to harms were higher in antineoplastic and immunomodulating drugs randomized clinical trials, while the median proportion of the space in the results section allocated to harms was 16.8%. In 67.6% of the articles, the space allocated to the authors’ list and affiliations was greater than the space in the results section allocated to descriptions of harms. No significant improvement in the score or the space allocation was observed during the study period. Conclusion: Reporting of harms in French academic drug randomized clinical trials is suboptimal; moreover, this shortcoming is a critical barrier to evaluating the benefit–risk ratio of drug randomized clinical trials. Thus, the authors should be encouraged to adhere to the Consolidated Standards of Reporting Trials Harms extension.
Diagnostic accuracy, risk assessment, and cost‐effectiveness of component‐resolved diagnostics for food allergy: A systematic review

Component‐resolved diagnostics (CRD) are promising tools for diagnosing food allergy, offering the potential to determine specific phenotypes and to develop patient‐tailored risk profiles. Nevertheless, the diagnostic accuracy of these tests varies across studies; thus, their clinical utility remains unclear. Therefore, we synthesized the evidence from studies investigating the diagnostic accuracy, risk assessment ability, and cost‐effectiveness of CRD for food allergy.
Ambient Air Pollution and Cancer Mortality in the Cancer Prevention Study II

Background: The International Agency for Research on Cancer classified both outdoor air pollution and airborne particulate matter as carcinogenic to humans (Group 1) for lung cancer. There may be associations with cancer at other sites; however, the epidemiological evidence is limited. Objective: The aim of this study was to clarify whether ambient air pollution is associated with specific types of cancer other than lung cancer by examining associations of ambient air pollution with nonlung cancer death in the Cancer Prevention Study II (CPS-II). Methods: Analysis included 623,048 CPS-II participants who were followed for 22 y (1982–2004). Modeled estimates of particulate matter with aerodynamic diameter <2. 5µm (PM2.5) (1999–2004), nitrogen dioxide (NO2) (2006), and ozone (O3) (2002–2004) concentrations were linked to the participant residence at enrollment. Cox proportional hazards models were used to estimate associations per each fifth percentile–mean increment with cancer mortality at 29 anatomic sites, adjusted for individual and ecological covariates. Results: We observed 43,320 nonlung cancer deaths. PM2.5 was significantly positively associated with death from cancers of the kidney {adjusted hazard ratio (HR) per 4.4 μg/m3=1.14 [95% confidence interval (CI): 1.03, 1.27]} and bladder [HR=1.13 (95% CI: 1.03, 1.23)]. NO2 was positively associated with colorectal cancer mortality [HR per 6.5 ppb=1.06 (95% CI: 1.02, 1.10). The results were similar in two-pollutant models including PM2.5 and NO2 and in three-pollutant models with O3. We observed no statistically significant positive associations with death from other types of cancer based on results from adjusted models. Conclusions: The results from this large prospective study suggest that ambient air pollution was not associated with death from most nonlung cancers, but associations with kidney, bladder, and colorectal cancer death warrant further investigation. https://doi.org/10.1289/EHP1249
Multi-resolution spectral input for convolutional neural network-based speech recognition

The convolutional deep neural network component applied frequently in current speech recognizers is trained on a context of consecutive spectral feature vectors. Here, we investigate whether we can extend the time span of this input and reduce the number of spectral features at the same time by using a multi-resolution spectrum as input. In the proposed multi-resolution scheme, the network processes the nearby neighbors of the actual frame using the standard resolution, while it applies a gradually coarser resolution for more distant frames. Using this solution, we managed to extend the input of our network to a time context of 45 frames without increasing the number of input features, and we also achieved a relative error rate reduction of 3–4% compared to the conventional high-resolution representation. We report a phone error rate of 17.0% on the TIMIT core test set, which is competitive with the best scores published on this data set.
Are efforts to attract graduate applicants to UK medical schools effective in increasing the participation of under-represented socioeconomic groups? A national cohort study

Introduction Attracting graduates was recommended as a means of diversifying the UK medical student population. Graduates now make up nearly a quarter of the total medical student population. Research to date has focused on comparing the sociodemographic characteristics of applicants to and/or students on traditional and graduate entry programmes (GEMs), yet GEMs account for only 40% of the graduate medical student population. Thus, we aimed to compare the sociodemographic characteristic and outcomes of graduates and non-graduate applicants across a range of programmes. Methods This was an observational study of 117 214 applicants to medicine who took the UK Clinical Aptitude Test (UKCAT) from 2006 to 2014 and who applied to medical school through Universities and Colleges Admissions Service (UCAS). We included applicant demographics, UKCAT total score and offers in our analysis. Applicants were assigned as graduates or non-graduates on the basis of their highest qualification. Multiple logistic regression was used to predict the odds of receiving an offer, after adjusting for confounders. Results Irrespective of graduate or non-graduate status, most applicants were from the highest socioeconomic groups and were from a white ethnic background. Receiving an offer was related to gender and ethnicity in both graduates and non-graduates. After adjusting for UKCAT score, the OR of an offer for graduates versus non-graduates was approximately 0.5 (OR=0.48, 95% CI 0.46 to 0.49). Discussion Our findings indicate that the aim of diversifying the medical student population on socioeconomic grounds by attracting graduates has been only marginally successful. Graduate applicants from widening access backgrounds are less likely than others to be offered a place at medical school. Different approaches must be considered if medicine is to attract and select more socially diverse applicants.
Selective breeding for high and low antibody responses to inactivated Newcastle disease virus in Japanese quails.

Two lines of Japanese quail were divergently selected for high and low antibody responses after being twice injected at 4 and 6 weeks of age with inactivated Newcastle disease virus antigen. After seven generations of selection, the serum antibody level in the high line was 24% greater than the level in the unselected control lines, whereas the low line antibody level was approximately 37% less than that in the control line. The estimated heritability (H2S + D) was approximately . 12 +/- . 50. The realized h2, calculated from coefficient of regression formula on seven generations (G3 to G9 ), was . 07.
A New Algorithm Using the Non-Dominated Tree to Improve Non-Dominated Sorting

Non-dominated sorting is a technique often used in evolutionary algorithms to determine the quality of solutions in a population. The most common algorithm is the Fast Non-dominated Sort (FNS). This algorithm, however, has the drawback that its performance deteriorates when the population size grows. The same drawback applies also to other non-dominating sorting algorithms such as the Efficient Non-dominated Sort with Binary Strategy (ENS-BS). An algorithm suggested to overcome this drawback is the Divide-and-Conquer Non-dominated Sort (DCNS) which works well on a limited number of objectives but deteriorates when the number of objectives grows. This article presents a new, more efficient algorithm called the Efficient Non-dominated Sort with Non-Dominated Tree (ENS-NDT). ENS-NDT is an extension of the ENS-BS algorithm and uses a novel Non-Dominated Tree (NDTree) to speed up the non-dominated sorting. ENS-NDT is able to handle large population sizes and a large number of objectives more efficiently than existing algorithms for non-dominated sorting. In the article, it is shown that with ENS-NDT the runtime of multi-objective optimization algorithms such as the Non-Dominated Sorting Genetic Algorithm II (NSGA-II) can be substantially reduced.
Differentially Private Federated Learning: A Client Level Perspective

Federated learning is a recent advance in privacy protection. In this context, a trusted curator aggregates parameters optimized in decentralized fashion by multiple clients. The resulting model is then distributed back to all clients, ultimately converging to a joint representative model without explicitly having to share the data. However, the protocol is vulnerable to differential attacks, which could originate from any party contributing during federated optimization. In such an attack, a client's contribution during training and information about their data set is revealed through analyzing the distributed model. We tackle this problem and propose an algorithm for client sided differential privacy preserving federated optimization. The aim is to hide clients' contributions during training, balancing the trade-off between privacy loss and model performance. Empirical studies suggest that given a sufficiently large number of participating clients, our proposed procedure can maintain client-level differential privacy at only a minor cost in model performance.