Miracle-dz/UniFAR-FTUs huggingface dataset:
Two Amino Acid Residues of Transposase Contributing to Differential Transposability of IS1 Elements inEscherichia coli

ABSTRACT Escherichia coli W3110 contains four types of IS1 elements in the chromosome. Using an insertion element entrapping system, we collected 116 IS1 plasmid insertion mutants, which resulted from a minimum of 26 independent IS1 insertion events. All of them had insertions of IS1 of the IS1A (IS1E and IS1G) type. Inspection of the transposase sequences of the four IS1 types and the IS1 of the resistance plasmid R100 showed that two amino acid residues, His-193 and Leu-217 of transposase, might contribute to differential transposability of IS1 elements in W3110. The two amino acid residues of the transposase in IS1A (IS1E and IS1G) were altered separately by site-directed mutagenesis, and each mutant was found to mediate transposition at a frequency about 30-fold lower than that of IS1A (IS1E and IS1G). Thus, the assumption that His-193 and Leu-217 of transposase contribute to differential transposability of IS1 elements in W3110 was confirmed.
Wall-clutter mitigation using cross-beamforming in through-the-wall radar imaging

A new technique for removal of the wall EM returns in Through-the-Wall Radar Imaging is presented. It is based on the spatial notch-filtering to separate wall and target reflections. The proposed technique forms squint beams at the receiver using a divided aperture. In doing so, it removes the strong wall signature without eliminating those of the targets. The proposed scheme provides desirable 3D target detection which is evaluated using real data examples from Through-the-Wall radar imaging experiments.
High-risk behaviors among adult men and women in Botswana: Implications for HIV/AIDS prevention efforts

Abstract The government of Botswana has been spending a lot of money in the prevention, treatment, care and support for HIV/AIDS patient for decades. This paper uses data from the third Botswana AIDS Impact Survey (BAIS III) to explore high-risk behaviors of adults and how they affect government efforts to stop the spread of HIV/AIDS. The objective of this paper is to fill in the gap on the assessment of high-risk behaviors associated with HIV/AIDS and their implications on HIV/AIDS prevention efforts. A nationally representative sample of 10,159 men and women aged 20–64 years who had successfully completed the BAIS III individual questionnaire were used in the study. Both descriptive and binary logistic regression analyses were used for analysis. Crude odds ratios were obtained from gross effects model while adjusted odds ratios (AOR) were obtained from the net effects model. Statistically significant association was observed between multiple current partners and alcohol consumption (AOR = 1.5), drug abuse (AOR = 1.7), transactional sex (AOR = 2.6) and intergenerational sex (AOR = 1.07). Furthermore, statistically significant association was seen for inconsistent condom use and having tested for HIV (AOR = 1.5). These results show a worrying tendency that despite government's efforts to stop the spread of HIV/AIDS, adults in Botswana continue to indulge in high-risk behaviors. Therefore, any programs and policies on HIV/AIDS should first target these high-risk behaviors.
Regression From Game-Oriented to Traditional School

Pupils in Sweden are socialized in commercial off-the-shelf games, and, therefore, game-oriented formal education can constitute a foundation for further socialization of pupils excluded in school. However, digital illiteracy and traditional views among school staff forced a regression from the game-oriented formal trial education in this study back to the traditional education form. Research questions were as follows: How did the pupils act upon the consequences of the regression? How can these acts inform the design of education in digital culture? These questions were addressed using ethnography over 3 years. The pupils' acts differed depending on their socialization in school and in games. While the game-oriented formal education included all in the socialization process, the regression caused half of the pupils to drop out. The pupils' acts are discussed with a conceptual framework. Conclusions show the need for digital literacy and understanding pupils' perspectives on education among school staff.
Management of Transient Monocular Vision Loss and Retinal Artery Occlusions

ABSTRACT Acute transient or permanent retinal occlusive disease requires prompt medical attention and can be an ophthalmological emergency. Central retinal artery occlusion leads to permanent and severe monocular visual loss in the majority of patients. Transient monocular vision loss leaves no permanent deficits, but requires the same level of clinical vigilance, as it portends possible future adverse events, including loss of vision and stroke. Acute treatment options remain limited, and secondary prevention of cerebral ischemic events is the mainstay of management. This article reviews the current evidence for managing patients with retinal ischemia.
Adding Visual Annotations to Model Elements in Eclipse-Based Diagram Editors

Graphical models are useful for discussing different aspects of processes, structures or requirements. The visual syntax of a standard modelling language cannot support all such aspects. There are several cases where it would be desirable to decorate the symbols in a diagram with additional visual annotations. This way, it is possible to include specific information (such as security requirements) that cannot be expressed graphically when using the standard modelling language. In our paper, we present plug-ins for the Eclipse Modelling Framework that make it possible to decorate diagrams with additional visual annotations. These plug-ins can be added to Eclipse-based modelling tools, thus allowing them to enrich the expressiveness of their diagrams.
Employees’ intention to blow the whistle: The role of fairness and moral identity

In acest studiu ne-am concentrat pe concepte cheie - identitate morală și corectitudine - cu scopul de a explica intenția de a denunța neregulile din organizație. Am examinat relația dintre intenția de a denunța neregulile din organizație și identitatea morală, precum și efectul de moderare al percepției corectitudinii procedurale a sefului direct in această relație. Rezultatele noastre au arătat că in cazul angajaților (N = 278) cu un nivel inalt de identitate morală se intâlnește o probabilitate mai mare de a raporta din proprie inițiativă neregulile pe care le-au identificat, in timp ce acest lucru este mai puțin probabil in cazul angajaților cu un nivel scăzut de identitate morală. In plus, am constatat că impactul identității morale asupra intenției de a denunța neregulile este amplificat de un grad ridicat de corectitudine procedurală, in timp ce un grad redus nu influențează semnificativ relația. Aceste constatări aduc perspective noi in studiul intenției de a denunța neregulile din organizație.
Setting Priorities for Optimizing Vascular Access Decision Making – An International Survey of Patients and Clinicians

Background Many decisions around vascular access for haemodialysis warrant a collaborative treatment decision-making process, involving both clinician and patient. Yet, patients’ experiences in this regard have been suboptimal. Although clinical practice guidelines could facilitate collaborative decision making, they often focus on the clinicians’ side of the process, while failing to address the patients’ perspective. The objective of this study was to explore and compare kidney patients’ and clinicians’ views on what vascular access-related decisions deserved priority for developing guidelines that will contribute to optimizing collaborative decision making. Methods In the context of updating their vascular access guideline, European Renal Best Practice surveyed an international panel of 85 kidney patients, 687 nephrologists, 194 nurses, and 140 surgeons/radiologists. In an electronic questionnaire, respondents rated 42 vascular access-related topics on a 5-point Likert scale. Based on mean standardized ratings, we compared priority ratings between patients and each clinician group. Results Selection of access type and site, as well as prevention of access infections received top priority across all respondent groups. Patients generally assigned higher priority to decisions regarding managing adverse effects of arteriovenous access and patient involvement in care, while clinicians more often prioritized decisions around sustaining patients’ access options, technical aspects of access creation, and optimizing fistula maturation and patency. Conclusion Apart from identifying the most pressing knowledge gaps, our study provides pointers for developing guidelines that may improve healthcare professionals’ understanding of when to involve patients along the vascular access pathway.
Socialization of adolescents' weight-related behaviors: The roles of best friend and group contagion and adolescent popularity

Diana Rancourt: Socialization of Adolescents’ Weight-Related Behaviors: The Roles of Best Friend and Group Contagion and Adolescent Popularity (Under the direction of Mitchell J. Prinstein) This study examined two peer relations concepts that may be relevant for understanding weight-related behaviors in adolescents: socialization and popularity. Data from 582 youth in grades 6-8 at an initial time point were used to examine best friend and friendship group socialization of weight-related behaviors, as well as the reciprocal effects of popularity on weight-related behaviors. Measures were administered at two time points and included selfreport indices of body dissatisfaction, body-related cognitions, and dieting practices. Sociometric assessments were conducted to examine friendships and two forms of popularity (i.e., preferenceand reputation-based). Results suggested that both best friend and friendship group socialization were important predictors of body dissatisfaction, musclegaining behaviors, and diet-based exercise, and that gender moderated these processes. Popularity was both an outcome and predictor of weight-related behaviors, and moderated best friend socialization of diet-based exercise. Overall, results were modest and suggest complex processes in peer socialization of weight-related behaviors.
The Tight-Junction Protein Claudin-6 Induces Epithelial Differentiation from Mouse F9 and Embryonic Stem Cells

During epithelialization, cell adhesions and polarity must be established to maintain tissue assemblies and separate the biological compartments in the body. However, the molecular basis of epithelial morphogenesis, in particular, a role of cell adhesion molecules in epithelial differentiation from stem cells, remains unclear. Here, we show that the stable and conditional expression of a tight-junction protein, claudin-6 (Cldn6), triggers epithelial morphogenesis in mouse F9 stem cells. We also demonstrate that Cldn6 induces the expression of other tight-junction and microvillus molecules including Cldn7, occludin, ZO-1α+, and ezrin/radixin/moesin-binding phosphoprotein50. These events were inhibited by attenuation of Cldn6 using RNA interference or the C-terminal half of Clostridium Perfringens enterotoxin. Furthermore, similar results were obtained in mouse embryonic stem cells. Thus, we have uncovered that the Cldn6 functions as a novel cue to induce epithelial differentiation.
Tight and Simple Web Graph Compression

Analysing Web graphs has applications in determining page ranks, fighting Web spam, detecting communities and mirror sites, and more. This study is however hampered by the necessity of storing a major part of huge graphs in the external memory, which prevents efficient random access to edge (hyperlink) lists. A number of algorithms involving compression techniques have thus been presented, to represent Web graphs succinctly but also providing random access. Those techniques are usually based on differential encodings of the adjacency lists, finding repeating nodes or node regions in the successive lists, more general grammar-based transformations or 2-dimensional representations of the binary matrix of the graph. In this paper we present two Web graph compression algorithms. The first can be seen as engineering of the Boldi and Vigna (2004) method. We extend the notion of similarity between link lists, and use a more compact encoding of residuals. The algorithm works on blocks of varying size (in the number of input lines) and sacrifices access time for better compression ratio, achieving more succinct graph representation than other algorithms reported in the literature. The second algorithm works on blocks of the same size, in the number of input lines, and its key mechanism is merging the block into a single ordered list. This method achieves much more attractive space-time tradeoffs.
Cooptive Corporate Actor Networks: A Reconsideration of Interlocking Directorates Involving American Manufacturing

*Writing and analysis for this article were accomplished during a leave of absence spent in the Department of Sociology, State University of New York at Albany. I greatly appreciate the excellent facilities made available to me there by R. Farrell, R. Hall, and N. Lin. As part of the ongoing work under the Project in Structural Analysis at the Survey Research Center, University of California at Berkeley, this research was supported by a grant from the National Science Foundation (SOC77-22938). Able research assistance in coding the data on directors and establishments was provided by N. Anderson, K.P. Christman, J. Geschwind, and M. Lundgren. The data analyzed here, part of a more complete data set on market structure and cooptive relations, are available from the Reprint Librarian, Survey Research Center, UC, Berkeley, CA 94720 as Working Paper 21: "Market structure and cooptive networks for two-digit SIC manufacturing industries in the 1967 U.S. economy. " I have benefited from comments by R. Hall, E. Litwak, and an anonymous ASQ reviewer. Portions of this article were presented at the 1979 annual meetings of the American Sociological Association. Cooptive Corporate Actor Networks
The Extent of Adoption of HRIS: An Empirical Investigation with Mediators & Moderators

Existing literature on the HRIS acceptance is exploratory with little emphasis on rigorous theoretical development. In the current study, we bring together disparate threads of HRIS research and employ the innovation diffusion model and the TAM model to explicate the extent of adoption of HRIS among Indian firms. The findings of empirical research show that OHR, FHR and SHR contribute to the performance of HR systems which further drives the extent of adoption within the organization. Further, the variable ‘performance consideration’ acts as a mediator and the variation in organizational size and work experience do not lead to drastic changes in extent of adoption. These results suggest that the impact of HRIS functions does not vary with the intensity of organization size, work experience and technology facilitation. Lastly, the study demonstrates the progressive emergence of strategic HR function within HRIS which is a major deviation from previous works.
Developing a conceptual model for investigating adoption of knowledge management system in Saudi Arabian public sector

This paper employed literature analysis approach and the Technology-Organisation-Environment TOE as a guiding theoretical framework to propose and discuss a research model for investigating the factors responsible for influencing the adoption of knowledge management systems KMS in public sector organisations in Saudi Arabia. A cautious analysis of different models has been the basis for selecting the TOE framework as the guiding model to be used for this research. This is due to the fact that this framework not only covers the technological aspects of analysing the adoption of KM systems but more importantly also explores their organisational and environmental contexts. Hence, this model provides a complete analysis of the possible aspects to be considered for KM systems adoption in public sector organisations. The paper discussed and formulated 21 hypotheses describing the overall adoption of KM systems.
A Note on Mood, Modality, Tense and Aspect Affixes in Turkish

The limited goal of this contribution is to analyse the order of the mood, modality, tense and aspect, verbal suffixes of Turkish in the light of my (1999) proposal on the functional structure of the clause. My hope is that the exercise, besides explaining away certain apparent counterexamples to a rigid hierarchy of functional projections, may shed a partly new light on this area of the grammar of Turkish. In Cinque (1999), I examined the relative order of free (particles) and bound (suffixes) grammatical morphemes corresponding to mood, modality, tense, aspect and voice distinctions in the languages of the world. The recurrent picture that one finds in this domain is that they not only are rigidly ordered with respect to each other (as partly anticipated in such works as Bybee 1985, Foley and Van Valin 1984, and Dik 1989), but that each of the mood, modality, tense, aspect, and voice categories is made up, at a finer level, of a number of distinct heads, which also appear to be rigidly ordered. The striking match between the order of these grammatical heads and the order of the corresponding adverbs was further taken there to suggest a rich and articulated functional structure above the lexical VP of the clause, where each adverb class corresponds to a mood, modality, tense, aspect or voice head in a one-to-one fashion (as does the specifier to a head in a classical X-bar structure Chomsky 1970, Kayne 1994). The order of such X-bar projections is approximately that shown in (1):
The Adoption of Personal Internet Banking in Vietnam

Based on previous studies a model of the determinants of an individual’s intentions to use Personal Internet Banking (PIB) services was formulated, tested and developed to arrive at a final model. Independent determinants included an individual’s personal characteristics, personality traits, and level of trust in the bank. New findings stressed the important mediation roles played by Perceived Ease of Use and Perceived Usefulness in the total effect of Trust on Behavioral Intention while all of the personal characteristics, except for Position Description, were found to be less important than in several previous studies. Among the personality traits the direct effect of Agreeableness on Perceived Ease of Use and Neuroticism on Behavioral Intention had not been reported in previous PIB studies and the same was true for other significant correlations involving Extraversion, Conscientiousness, and Openness to Experience. Based on the final causal model practical implications of the findings are discussed. Based on previous studies a model of the determinants of anindividual’s intentions to use Personal Internet Banking (PIB) services wasformulated, tested and developed to arrive at a final model. Independentdeterminants included an individual’s personal characteristics, personalitytraits, and level of trust in the bank. New findings stressed the importantmediation roles played by Perceived Ease of Use and PerceivedUsefulness in the total effect of Trust on Behavioral Intention while all of thepersonal characteristics, except for Position Description, were found to beless important than in several previous studies. Among the personalitytraits the direct effect of Agreeableness on Perceived Ease of Use andNeuroticism on Behavioral Intention had not been reported in previousPIB studies and the same was true for other significant correlationsinvolving Extraversion, Conscientiousness, and Openness to Experience.Based on the final causal model practical implications of the findings arediscussed.Keywords: Five-Factor Model, Personal Internet Banking, StructuralEquation Modeling, Technology Acceptance Model
Labor Epidural Analgesia and Breastfeeding

Despite widespread use of epidural analgesia during labor, no consensus has been reached among obstetric and anesthesia providers regarding its effects on breastfeeding. The purpose of this review was to examine the relationship between labor epidural analgesia and breastfeeding in the immediate postpartum period. PubMed, Cochrane Library, and Cumulative Index to Nursing and Allied Health Literature were searched for articles published in 1990 or thereafter, using the search term breastfeeding combined with epidural, labor epidural analgesia, labor analgesia, or epidural analgesia. Of 117 articles, 23 described empirical studies specific to labor epidural analgesia and measured a breastfeeding outcome. Results were conflicting: 12 studies showed negative associations between epidural analgesia and breastfeeding success, 10 studies showed no effect, and 1 study showed a positive association. Most studies were observational. Of 3 randomized controlled studies, randomization methods were inadequate in 2 and not evaluable in 1. Other limitations were related to small sample size or inadequate study power; variation and lack of information regarding type and dosage of analgesia or use of other intrapartum interventions; differences in timing, definition, and method of assessing breastfeeding success; or failure to consider factors such as mothers’ intention to breastfeed, social support, siblings, or the mother’s need to return to work or school. It is also unclear to what extent results are mediated through effects on infant neurobehavior, maternal fever, oxytocin release, duration of labor, and need for instrumental delivery. Clinician awareness of factors affecting breastfeeding can help identify women at risk for breastfeeding difficulties in order to target support and resources effectively.
Understanding Why Medication Administration Errors May Not Be Reported

Because the identification and reporting of medication administration errors (MAE) is a nonautomated and voluntary process, it is important to understand potential barriers to MAE reporting. This paper describes and analyzes a survey instrument designed to assist in evaluating the relative importance of 15 different potential MAE-reporting barriers. Based on the responses of over 1300 nurses and a confirmatory LISREL analysis, the 15 potential barriers are combined into 4 subscales: Disagreement Over Error, Reporting Effort, Fear, and Administrative Response. The psychometric properties of this instrument and descriptive profiles are presented. Specific suggestions for enhancing MAE reporting are discussed.