Miracle-dz/UniFAR-FTUs huggingface dataset:
Same-day breast cancer surgery: a qualitative study of women's lived experiences.

PURPOSE/OBJECTIVES To understand the experiences of women having same-day breast cancer surgery and make recommendations to assist healthcare professionals effect change to enhance quality of care. RESEARCH APPROACH Thematic analysis of audiotaped interviews. SETTING Outpatient departments of two city hospitals on the east coast of Canada. PARTICIPANTS Purposive sample of 13 women who had undergone same-day breast cancer surgery. METHODOLOGIC APPROACH A constructivist approach with in-depth interviews and comparative analysis to develop and systemically organize data into four major interrelated themes and a connecting essential thread. MAIN RESEARCH VARIABLES Women's experiences with same-day breast cancer surgery. FINDINGS The themes of preparation, timing, supports, and community health nursing intervention were of paramount importance for effective coping and recovery. Women who had a positive experience with same-day breast cancer surgery also reported having adequate preparation, appropriate timing of preparation, strong support systems, and sufficient community health nursing intervention. Those reporting a negative experience encountered challenges in one or more of the identified theme areas. CONCLUSIONS Same-day surgery is a sign of the times, and the approach to it is changing. Healthcare systems need to be responsive to such changes. Although same-day surgery for breast cancer is not suitable for every patient, women undergoing this type of surgery should be assessed individually to determine whether it is appropriate for them. INTERPRETATION Women undergoing breast cancer surgery should be screened for same-day surgery suitability. Those having same-day breast cancer surgery should be prepared adequately with timely education. Most importantly, such women should receive community health nursing follow-up for assessment, continuing education, and psychosocial support.
Development of the blood vessels and extracellular spaces during postnatal maturation of rat cerebral cortex

As part of a larger study of the development of postnatal rat cerebral cortex, this report deals with the maturation of the cortex as a tissue from birth to twenty‐one days of age. The changes in the numerical density of cells and blood vessels and the thickness of the cortex at successive ages were followed on light micrographs, and both were related to the ultrastructural observations on routine electron microscopic preparations. The maturation of the cortex is divided into two periods: The first ten days during which the growth to adult dimensions occurs and few patent blood vessels but large extracellular spaces are to be found, and the second ten days in which the majority of the vessels develop patent lumina, the perivascular sheath of astrocyte end‐feet develops, and the large extracellular spaces disappear concomitant with the maturation of the neuropil.
THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCE

The method of calculation is shown whereby a formula has been derived that states approximately the ratio of the rate of accumulation of advantageous mutant genes in a population that undergoes recombination to the rate in an otherwise nonrecombining one. A table is given showing the ratios thus found for different frequencies of advantageous mutations and different degrees of their advantage. I t is shown that this calculation does not apply for mutant genes that act advantageously only when in some special combinations with one or more other mutant ,genes, and that as far as these cases of special synergism are concerned recombining lines have no evolutionary advantage over non-recombining ones. Other limitations of the formula are pointed out and assessed. I t is explained that most factors that retard the rate of recombination--for example, linkage, rari ty of outbreeding, intercalation of sexual reproduction between more frequent cycles of asexual propagation, and partial isolation between subpopulat ions--must usually cause little long-term retardation of the speed of advance that is fostered by recombination. Moreover, even where long-term evolution has virtually ceased, recombination of mutant genes still confers upon a population the means of adopting short-term genetic "dodges", that adjust it to ecological and "physical" changes in its circumstances, much more rapidly than would be possible for a comparable asexual population. Under conditions where only stability of type is needed, a non-recombining population does not actually degenerate as a result of an excess of mutation over selection, after the usual equilibrium between these pressures is reached. However, a kind of irreversible ratchet mechanism exists in the non-recombining species (unlike the recombining ones) that prevents selection, even if intensified, from reducing the mutational loads below the lightest that were in existence when the intensified selection started, whereas, contrariwise, "drif t" and what might be called "selective noise" must allow occasional slips of the lightest loads in the direction of increased weight.
Early feeding problems in a normal population

The prevalence of parentally experienced infant feeding problems was explored in two samples (N = 841 and N = 567) of infants, aged between 30 and 71 weeks. Correlates to specific problem types were sought. One-fourth of the parents had experienced feeding problems during the infant's first 6 months and more than 10% reported ongoing problems. Colic was the most commonly reported early appearing problem, while refusal of solids, poor appetite, and general refusal to eat were the most common problems after the first 6 months. Maternal health factors, severe and longlasting breastfeeding problems, and problematic mealtime behaviors were associated with colic, while vomiting was only related to breastfeeding problems. The refusal-to-eat group presented the largest number of correlates including family feeding problems, problematic meal behaviors, and health problems. The only aspects distinguishing all problem groups from controls were parental anxiety about infant health and sibling feeding problems.
Abundances and Evolution of Lithium in the Galactic Halo and Disk

We have measured the Li abundance of 18 stars with -2 ≲ [Fe/H] ≲ -1 and 6000 ≲ Teff ≲ 6400 K, a parameter range that was poorly represented in previous studies. We examine the Galactic chemical evolution (GCE) of this element, combining these data with previous samples of turnoff stars over the full range of halo metallicities. We find that A(Li) increases from a level of ~2.10 at [Fe/H] = -3.5 to ~2.40 at [Fe/H] = -1.0, where A(Li) =(n(Li)/n(H)) + 12.00. We compare the observations with several GCE calculations, including existing one-zone models and a new model developed in the framework of inhomogeneous evolution of the Galactic halo. We show that Li evolved at a constant rate relative to iron throughout the halo and old disk epochs but that during the formation of young disk stars, the production of Li relative to iron increased significantly. These observations can be understood in the context of models in which postprimordial Li evolution during the halo and old disk epochs is dominated by Galactic cosmic-ray fusion and spallation reactions, with some contribution from the ν-process in supernovae. The onset of more efficient Li production (relative to iron) in the young disk coincides with the appearance of Li from novae and asymptotic giant branch (AGB) stars. The major challenge facing the models is to reconcile the mild evolution of Li during the halo and old disk phases with the more efficient production (relative to iron) at [Fe/H] > -0.5. We speculate that cool-bottom processing (production) of Li in low-mass stars may provide an important late-appearing source of Li, without attendant Fe production, that might explain the Li production in the young disk.
Testing Hypotheses about Other People

This investigation examined the influence of the manner in which hypotheses about other people. are framed on the strategies that individuals formulate to test these hypotheses. Male and female participants formulated question-asking strategies to test hypotheses about other people. For some participants, hypotheses were framed exclusively in terms of attributes that would confirm the hypothesis. For other participants, hypotheses were framed both in terms of attributes that would confirm and in terms of attributes that would disconfirm the hypothesis. In each case participants planned to test their hypotheses by preferentially soliciting, by means of the questions they chose to ask, behavioral evidence that would confirm their hypotheses.
Cultures of mixing: understanding partnerships across ethnicity

This article presents an extensive analysis of ‘cultures of mixing’―that is, relationships between partners from different ethnic backgrounds―based on 2001 British census data. The data is used to show how ‘mixed’ partnerships are relevant to aspects of current debates about the nature of ethnic relations in contemporary Britain. We begin with a discussion of dominant stereotypes around mixed race/ethnicity partnerships in Britain and their links to dystopian visions of majority and minority ethnic relations, before looking at frameworks of understanding that offer a challenge to these gloomy diagnoses, and in particular the concept of ‘convivial culture’. This discussion is followed by an analysis of the location and socio-economic characteristics of ‘cultures of mixing’. We argue that ‘cultures of mixing’ are spatially and socially uneven, and appear to be underpinned by more material and equity-based features of social life and provision.
Results of Infrapopliteal Endovascular Procedures Performed in Diabetic Patients with Critical Limb Ischemia and Tissue Loss from the Perspective of an Angiosome-Oriented Revascularization Strategy

Our aim was to describe our experience with infrapopliteal endovascular procedures performed in diabetic patients with ischemic ulcers and critical ischemia (CLI). A retrospective study of 101 procedures was performed. Our cohort was divided into groups according to the number of tibial vessels attempted and the number of patent tibial vessels achieved to the foot. An angiosome anatomical classification of ulcers were used to describe the local perfusion obtained after revascularization. Ischemic ulcer healing and limb salvage rates were measured. Ischemic ulcer healing at 12 months and limb salvage at 24 months was similar between a single revascularization and multiple revascularization attempts. The group in whom none patent tibial vessel to the foot was obtained presented lower healing and limb salvage rates. No differences were observed between obtaining a single patent tibial vessel versus more than one tibial vessel. Indirect revascularization of the ulcer through arterial-arterial connections provided similar results than those obtained after direct revascularization via its specific angiosome tibial artery. Our results suggest that, in CLI diabetic patients with ischemic ulcers that undergo infrapopliteal endovascular procedures, better results are expected if at least one patent vessel is obtained and flow is restored to the local ischemic area of the foot.
A look at the acts of identity theory through a social network analysis of Portuguese-based creoles in West Africa

This paper examines a hypothesis in the Acts of Identity theory that suggests a complementary relationship between the variant attributes of an individual's linguistic presentation and the individual's social identity. Through the mathematical modeling of social network analysis, the paper examines 169 lexical relationships between 29 speakers of Portuguese-based Creoles in West Africa. The resulting sociometric graphs, at the lexical and phonetic levels, find six network clusters in the data. The research also finds complementary relationships between these six network clusters and other social grouping features. The paper thus concludes with the objective mathematical modeling of social network analysis substantiating the notion of a complementary relationship between the variant attributes of an individual's linguistic presentation and the individual's social identity. The conclusion finds that the phonetic level may carry most of the load in marking social identity, and that the lexical level may carry a lighter load in this area. The conclusion thus finds that the lexicon may be a rather weak feature in the function of marking social identity, and therefore flexible and open to lexical enrichment, adlexification (or relexification? ), as the stronger identity marking features of the phonetic level can be overlaid on the lexical additions. The conclusion also suggests that the social structure of the post-creole continuum may be one of social fractures and clusters, like any other language, rather than one analogous with a linear continuum of lects.
CEACAM1 expression in cutaneous malignant melanoma predicts the development of metastatic disease.

PURPOSE The cell adhesion molecule CEACAM1 is involved in intercellular adhesion and subsequent signal transduction events in a number of epithelia. CEACAM1 downregulation has been demonstrated in colorectal and prostate carcinomas. This study sought to analyze whether its expression in malignant melanoma is associated with metastasis. PATIENTS AND METHODS CEACAM1 expression was immunohistochemically evaluated in 100 primary cutaneous malignant melanomas and correlated with metastasis in a 10-year follow-up. Furthermore, CEACAM1 expression was analyzed in metastatic lesions (11 distant metastases and six sentinel lymph node metastases). Univariate Kaplan-Meier analysis and multivariate Cox proportional hazard regression analysis adjusted for standard prognostic indicators were performed to assess the prognostic relevance of CEACAM1 expression. RESULTS A total of 28 of 40 patients with CEACAM1-positive primary melanomas developed metastatic disease, compared with only six of 60 patients with CEACAM1-negative melanomas. Often, the strongest CEACAM1 expression was observed at the invading front. In addition, CEACAM1 expression was preserved in the metastatic lesions. Kaplan-Meier analysis revealed a highly significant association between CEACAM1 expression and metastasis (P <.0001); multivariate Cox regression analysis, including CEACAM1 expression status adjusted for tumor thickness, presence of ulceration, and mitotic rate, confirmed that CEACAM1 is an independent factor for the risk of metastasis and demonstrated that the predictive value of CEACAM1 expression is superior to that of tumor thickness. CONCLUSION Expression of the cell adhesion molecule CEACAM1 in the primary tumors in melanoma patients is associated with the subsequent development of metastatic disease. This raises the possibility of a functional role for this cell adhesion molecule in the metastatic spread it indicates.
Carbamazepine-Associated Severe Left Ventricular Dysfunction

Introduction: The cardiovascular effects of carbamazepine are well-known but left ventricular dysfunction is rarely reported. Case Report: We describe 2 cases of severe carbamazepine-associated left ventricular dysfunction during massive self intoxications in young patients without preexistent cardiac disease. We compare our cases to the available literature and discuss the mechanisms implied in the development of left ventricular dysfunction following carbamazepine overdose. Bedside echocardiography was useful in both diagnosis and treatment.
Is There a Relationship Between the Myers-Briggs Type Indicator and Emotional Intelligence?

Presents the results of a research study, covering 177 managers. This research was designed specifically to examine the relationship between emotional intelligence (EI) and the Myers‐Briggs type indicator (MBTI) profiles of the sample population. Indicates that the dominant MBTI function of Intuition (and the associated MBTI profiles) is significantly and positively related to higher levels of EI. In looking at specific MBTI scales, the lack of significant relationships between high Feeling scores and EI is seen as somewhat surprising. However, this may in part be due to under‐representation of high “feeling” participants in the research study and, in part, due to methodological limitations of comparing data from normative and ipsative instruments. Provides some support overall for the proposed relationship between the MBTI and EI and also highlights potential areas for future research.
The mobile phone in street protest: Texting, tweeting, tracking, and tracing

This paper examines the role of information provision through mobile communication in mass street protest. The argument is based on two case studies: (a) the civic outrage of young people concerning the destruction of a youth centre in Copenhagen, Denmark in 2006 and (b) the use of mobile phones in antifascist protests in Dresden, Germany in 2011. The cases are analysed across three dimensions that are relevant to mobile communication tactics for providing information in protest: Actors, power relations between the actors, and goals. By identifying the affordances of the mobile phone for providing information across these dimensions, we argue that mobile communication can be appropriated to increase activists’ repertoire of actions, foster resistance, and shut down opportunities. The ways in which the affordances of mobile phones limit and empower resistance are located at the intersection of coordination, mobilisation, and the creation of counter narratives as well as of the surveillance and maintenance of existing power relations.
Phonological similarity in free and serial recall: The effect of increasing retention intervals

The phonological similarity effect (or acoustic confusion effect) consists of poor serial recall performance for lists composed of similar‐sounding words compared to lists of dissimilar‐sounding items. Building on the work of Nairne and Kelley (1999), the extent to which this classical verbal short‐term memory effect changes over the course of a retention interval was investigated. The impact of the phonological similarity on memory performance over time was compared in three paradigms: order reconstruction, serial recall, and free recall. Participants were presented with two blocks of 15 lists composed of five monosyllabic words, one block containing phonologically similar words and the other phonologically distinct words. Recall occurred either after 2, 8, or 24 seconds retention interval filled with a digit shadowing task. Our results confirmed and extended those of Nairne and Kelley. In order reconstruction and serial recall tasks, a classical phonological similarity effect (i.e., decrement in perform.
Evaluation of ‘vision screening’ program for three to six-year-old children in the Republic of Iran

Background: Since 1996, vision screening of three to six-year-old children is conducted every year in Iran. We present outcomes of project review held in August 2006. Materials and Methods: Kindergarten teachers examined vision by using Snellen's illiterate ‘E’ chart. They used torchlight to detect strabismus. On a repeat test, if either eye had vision <20/30, the child was referred to the optometrist. A pediatric ophthalmologist examined and managed children with strabismus or amblyopia. Provincial managers supervised the screening program. The evaluator team assessed the coverage, yield, quality and feasibility, and cost-effectiveness of vision screening, as well as magnitude of amblyopia, and its risk factors. Result: In 2005, 1.4 million (67%) children were examined in all provinces of Iran. Opticians examined 90,319 (61%) children with defective vision that were referred to them. The prevalence of uncorrected refractive error, strabismus and amblyopia was 3.82% (95% CI 3.79 – 3.85), 0.39% (95% CI 0.38 – 0.40) and 1.25% (95% CI 1.24 – 1.26) respectively. Validity test of 7,768 children had a sensitivity of 74.5% (95% CI 72.7 – 76.3) and specificity of 97.2% (95% CI 96.7 – 97.7). The cost of amblyopia screening was US $ 1.5 per child. While the cost of screening and treating one child with amblyopia was US $ 245. Conclusion: A review of the vision screening of children in Iran showed it with screening and useful exercise and had a yield of 1:21. The coverage of vision screening was low and the management of children with amblyopia, low vision and refractive error needed strengthening.
Development of job-seeking ability in people with arthritis: evaluation of a pilot program

Working Horizons is an intervention designed to prevent work disability by addressing the internal and external barriers faced by people with arthritis in their attempts to enter or maintain their positions in the employment arena. The aim of the pilot study was to determine whether Working Horizons influenced participants' self-efficacy and psychological well-being and to describe the experience of Working Horizons from the perspectives of participants and employment advisors (EAs). The study was a pre-test post-test design with an Intervention Group (n=22) and Comparison Control Group (n=22). Quantitative data were collected by self-completed questionnaires at baseline and at six-months follow-up. Qualitative data were collected via open questions on the questionnaires, interviews with a sub-sample of 10 participants, and a focus group with EAs at the end of the programme. Pilot data suggested that Working Horizons was effective in terms of increasing participants' job-seeking self-efficacy. In addition, the Intervention Group showed significant improvements on self-esteem and satisfaction with life. Qualitative findings confirmed that participants felt more ‘confident’ in relation to seeking employment, were more accepting of their condition, felt more positive and had greater awareness of the social model of disability. Participants valued the emotional and instrumental support provided by the EAs, who acted as successful ‘work’ role models. Interventions, such as Working Horizons, may be an effective means of addressing work disability, acting as a gateway to statutory services. The value of suitable role models in mentoring capacities was highlighted.
Two independent genetic factors responsible for the associations of the IBD5 locus with Crohn's disease in the Czech population

Background: The role of the IBD5 locus in development of Crohn's disease (CD) has not been clarified. In the Czech population we examined its genetic association using variants of the SLC22A4 (rs1050152), SLC22A5 (rs2631367), two single nucleotide polymorphisms (SNPs) shown to be associated with CD in genome‐wide studies (rs6596075 and rs2188962), and four SNPs previously shown to tag the haplotype blocks 4, 7, 9, 10 of the IBD5 locus (IGR2063b_1, IGR2230a_1, IGR100Xa_1, IGR3236a_1). Methods: The genotype, phenotype, and allelic frequencies were compared between 469 unrelated patients with CD (177 pediatric‐onset, 292 adult‐onset) and 470 unrelated healthy controls, all Caucasians of Czech ancestry. Results: The most significant difference between patients and controls was found for the SNP rs6596075 (odds ratio [OR] = 0.70 for the G allele; 95% CI 0.52‐0.94) in the dominant model and SNP IGR2063b_1 (OR = 1.38 for the G allele; 95% CI 1.14‐1.67) in the log‐additive model. We found a strong linkage disequilibrium across the IBD5 locus except rs6596075. The haplotype consisting of minor alleles of all tested SNPs except rs6596075 was carried by 31% patients and 23% control subjects (OR = 1.35, 95% CI 1.06‐1.72). The association of variants in SLC22A4 and SLC22A5 was dependent on this risk haplotype, while the strong association of the rs6596075 was seemingly independent. In the analysis of subphenotypes we found only an association of the penetrating disease with rs6596075 (OR = 2.13; 95% CI 1.31‐3.47). Conclusions: Our study confirms the importance of IBD5 in determining CD susceptibility, and demonstrates that two independent genetic factors may be responsible for the association observed within this locus. (Inflamm Bowel Dis 2010)