Miracle-dz/UniFAR-FTUs huggingface dataset:
A neural marker for social bias towards in-group accents

Accents provide information about the speaker ’ s geographical, socio-economic, and ethnic background. Research in applied psychology and sociolinguistics suggests that we generally prefer our own accent to other varieties of our native language and attribute more positive traits to it. Despite the widespread in ﬂ uence of accents on social interactions, educational and work settings the neural underpinnings of this social bias toward our own accent and, what may drive this bias, are unexplored. We measured brain activity while participants from two different geographical backgrounds listened passively to 3 English accent types embedded in an adaptation design. Cerebral activity in several regions, including bilateral amygdalae, revealed a signi ﬁ cant interaction between the participants ’ own accent and the accent they listened to: while repetition of own accents elicitedanenhancedneuralresponse,repetitionoftheothergroup ’ saccentresultedinreducedresponsesclassicallyassociated with adaptation. Our ﬁ ndings suggest that increased social relevance of, or greater emotional sensitivity to in-group accents, may underlie the own-accent bias. Our results provide a neural marker for the bias associated with accents, and show, for the ﬁ rst time, that the neural response to speech is partly shaped by the geographical background of the listener.
Targeted employee retention: Performance-based and job-related differences in reported reasons for staying

What makes employees stay with a particular employer? To find out, we developed a content model of 12 retention factors in the context of previous theory and research and analyzed open-ended responses from 24,829 employees in the leisure and hospitality industry. Our coding of their comments supported the identified framework and revealed that job satisfaction, extrinsic rewards, constituent attachments, organizational commitment, and organizational prestige were the most frequently mentioned reasons for staying. High performers and nonhourly workers were more likely to cite advancement opportunities and organizational prestige as reasons for staying, whereas low performers and hourly employees were more likely to cite extrinsic rewards. These findings highlight the importance of differentiating human resource management practices when the goal is to retain valued employees. © 2009 Wiley Periodicals, Inc.
Evaluation of nutritional and biochemical parameters in spontaneously hypertensive rats following antihypertensive treatment.

INTRODUCTION One side effect of antihypertensive drugs is their impact on nutritional status and metabolism. The purpose of this study was to assess the nutritional and biochemical parameters in spontaneously hypertensive rats following treatment with antihypertensive drugs. MATERIAL AND METHODS The experiment was performed on 50 male spontaneously hypertensive rats (SHR), which were assigned to five groups: control (C), with perindopril (PR), with metoprolol (MT), with indapamide (ID), and with amlodipine (AM). All rats were provided ad libitum standard diet (with or without drugs) and distilled water. After 45 days, the animals were weighed and killed. Liver, kidney, heart, spleen, pancreas, and blood samples were collected. Concentrations of glucose, cholesterol, triglycerides, and albumin were assayed in serum. Morphology parameters, such as white blood cell, red blood cell, hematocrit, and lymphocyte counts were measured in the blood. Blood pressure was measured using a tail-cuff plethysmograph. RESULTS The results obtained indicate that the hypotensive drugs under investigation had no effect on the selected nutritional parameters. Perindopril significantly decreased the relative mass of the heart and amlodipine markedly decreased the relative mass of the pancreas. A markedly higher concentration of glucose in the group with indapamid, and a significantly lower concentration of triglycerides in the group with metoprolol, were observed. Indapamide and amlodipine markedly increased the value of red blood cells and hematocrit in the blood of SHR. CONCLUSIONS Long-term therapy with antihypertension drugs may influence tissue mass and biochemical and morphological status in the body.
Stability enhancement of power system by controlling HVDC power flow through the same AC transmission line

HVDC power transmission employing power electronic device provides a wide range of control in power transmission. Remote generators are sometimes used to supply power to infinite bus through a single circuit long ac transmission line. The system may loose stability after the clearance of a fault if the pre-fault power transfer or the fault clearance time is high. Simultaneous ac-dc power transfer through the transmission line may be used for power flow enhancement. It needs conversion of the line for simultaneous ac-dc power flow to keep the system stable with high values of pre fault power and fault clearance time. During the transient period after the clearance of the fault, ac power supply is kept off and the dc power flow is increased to produce a retarding torque to bring back the generator to its normal speed. HVDC current regulator having very fast control facility may be employed for this purpose. AC circuit breakers are then switched on and the ac power flow is resumed at its pre fault value without any oscillation. The power swing is low and the system is optimally damped at the end of first swing. If the augmentation facility of HVDC power controller is limited, proper governor control of remote generators may be used to reduce the total power flow and to maintain the dc power flow only. After the system becomes stable the ac power supply is switched-on and the power oscillation is minimized with HVDC power controller.
Determining Factors of Audit Committee Attributes: Evidence from Spain

The goal of this paper is to determine the factors that explain voluntary improvements in audit committee activity, independence and financial expertise, both individually and jointly, within a corporate governance environment other than those used in previous works. These audit committee characteristics have been selected because previous authors have found that these attributes improve the effectiveness of this monitoring committee. The findings included a relatively high level of the proxies of audit committee effectiveness for those companies which display the best practices in terms of their board of directors' independence and activities. At the same time, we observed a non‐linear relationship of substitution among internal control mechanisms, management ownership and audit committee characteristics.
Inside the unions: A comparative analysis of policy-making in Australian and British printing and telecommunication trade unions

This thesis consists of a comparative analysis of policy making in Australian and British telecommunications and printing trade unions. It tests empirically the validity of different models of union policy making and behaviour, whilst also assessing the strength of the research hypothesis, that informal micro-political influences inside unions - such as personal friendships, enmities and loyalties - affect union policy making to a greater extent than is acknowledged in the literature. In order to address the subject the following research questions were posed: How, and why, do unions adopt specific policies? What factors explain the different behaviour of similar unions, when faced with comparable policy choices? To ensure that policies of strategic significance were focused upon, three key areas were selected for study: recruitment, amalgamations and union efforts to influence the labour process. As a former senior union officer I realised that trade unions were often loathe to publically disclose those factors which informed their policy making processes. For this reason a qualitative, interview rich, methodology was adopted, which involved a longitudinal study, in which over 220 officers and staff, of the relevant unions were rviewed. The research revealed that policy making in all the featured unions was a rich and complex process, in which occupational, geographical, ideological and personality based factional groups all had a significant influence on policy makers, along with the institutional and political context within which the unions operated. The empirical evidence also showed that micro-political factors, in particular enmities and personal loyalties, along with the individual beliefs, values and ideologies of policy makers, profoundly influenced their policy choices. Finally the research corroborated the assertion that strategic policy choices, made by trade unions, have a significant affect on their success or failure as organisations.
Differential plasma proteome analysis in patients with high-altitude pulmonary edema at the acute and recovery phases

This study aimed to investigate the differential expression of plasma proteins in patients suffering from high-altitude pulmonary edema (HAPE) at different phases. A complete proteomic analysis was performed using two-dimensional gel electrophoresis followed by mass spectrometry in three patients with HAPE at the acute stage and recovery phase. Comparisons between the expression patterns of the patients with HAPE at the two different phases led to the identification of eight protein spots with a >1.5-fold difference in expression between the acute and recovery phases. These differentially expressed proteins were apolipoproteins, serum amyloid P component, complement components and others. Apolipoprotein A-I (Apo A-I), serum amyloid P component and fibrinogen were overexpressed in the patients with HAPE in the acute stage compared with their expression levels in the recovery phase. However, Apo A-IV and antithrombin-III were overexpressed in the patients with HAPE in the recovery phase compared with their expression levels in the acute stage. The results indicate that the differential plasma proteome in patients with HAPE may be associated with the occurrence of HAPE, and the expression changes of Apo A-I and A-IV may offer further understanding of HAPE to aid its prognosis, diagnosis and treatment.
Legal Minimum Wages and the Wages of Formal and Informal Sector Workers in Costa Rica

The classic dual economy models of developing countries hold minimum wages (among other institutions) accountable for persistent dualism. They note that applying or enforcing minimum wage laws in only one sector of the economy will create wage differentials which will not be eroded with labor mobility to the high wage sector. In this paper we use 12 years of micro data on thousands workers living in Costa Rica to test whether legal minimum wages have a differential impact on the wages of workers in the formal sector vs. informal sector, defined in various ways in accordance with the dual development models. The evidence from Costa Rica is contrary to the assumptions of these models. We find that increases in minimum wages not only raise the wages of workers in the urban formal sector (large urban enterprises) who are covered by minimum wage law, but they also increase the wages of all other workers covered by minimum wage legislation in what are traditionally regarded as informal sectors and where the legislation is often considered not to be enforced. Specifically, we provide evidence that minimum wages increase the wages of workers in small urban enterprises, large rural enterprises and small rural enterprises. Further, our results suggest that higher legal minimum wages raise the average wage of workers in these "informal" sectors more than in the urban formal sector. We concluded that in Costa Rica minimum wages are being enforced in the rural and small scale sectors and may actually work to reduce average wage differentials between these sectors and the urban formal sector. On the other hand, minimum wages have no significant impact on the wages of workers in another sector that is regarded as informal but which is not covered by minimum wage legislation: the self-employed workers (both urban and rural). Thus, one could argue that minimum wages may contribute to dualism between the formal and informal, defined as self-employed vs. salaried workers. However, we find no evidence of the bleaker scenario, that self-employed earnings are being lowered by minimum wages.
Human leukemia K562 cells: induction to erythroid differentiation by guanine, guanosine and guanine nucleotides.

BACKGROUND AND OBJECTIVE Human leukemic K562 cells are able to undergo erythroid differentiation in vitro when cultured with a variety of inducers, leading to increased expression of embryo-fetal globin genes such as the zita, epsilon and gamma-globin genes. Therefore the K562 cell line has been proposed as a very useful in vitro model system for determining the therapeutical potential of new differentiating compounds as well as for studying the molecular mechanism(s) that regulate changes in the expression of embryonic and fetal human globin genes. In this study we explored whether nucleoside triphosphates and related compounds are able to induce differentiation of K562 cells. METHODS K562 cell differentiation was studied using the benzidine test; hemoglobins were characterized by cellulose acetate gel electrophoresis and mRNA accumulation was investigated by Northern blot analysis. RESULTS The main conclusion of this paper is that guanine, guanosine and guanine ribonucleotides are effective inducers of K562 cell differentiation. Expression of both Hb Portland and Hb Gower 1 is increased in GTP-induced K562 cells. This increase is associated with greater gamma-globin mRNA accumulation. By contrast, ATP, CTP and UTP are not able to induce erythroid differentiation. INTERPRETATION AND CONCLUSIONS These findings suggest that guanine, guanosine and guanine ribonucleotides are inducers of erythroid differentiation of K562 cells. This is of some relevance since differentiating compounds have been proposed as antitumor agents. In addition, inducers of erythroid differentiation that stimulate gamma-globin synthesis might be considered in the experimental therapy of hematological diseases associated with a failure in the expression of adult beta-globin genes.
Assessment of methodological quality of primary studies by systematic reviews: results of the metaquality cross sectional study

Abstract Objectives To describe how the methodological quality of primary studies is assessed in systematic reviews and whether the quality assessment is taken into account in the interpretation of results. Data sources Cochrane systematic reviews and systematic reviews in paper based journals. Study selection 965 systematic reviews (809 Cochrane reviews and 156 paper based reviews) published between 1995 and 2002. Data synthesis The methodological quality of primary studies was assessed in 854 of the 965 systematic reviews (88.5%). This occurred more often in Cochrane reviews than in paper based reviews (93.9% v 60.3%, P < 0.0001). Overall, only 496 (51.4%) used the quality assessment in the analysis and interpretation of the results or in their discussion, with no significant differences between Cochrane reviews and paper based reviews (52% v 49%, P = 0.58). The tools and methods used for quality assessment varied widely. Conclusions Cochrane reviews fared better than systematic reviews published in paper based journals in terms of assessment of methodological quality of primary studies, although they both largely failed to take it into account in the interpretation of results. Methods for assessment of methodological quality by systematic reviews are still in their infancy and there is substantial room for improvement.
Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse.

Fourteen patients with chronic myeloid leukemia (CML) relapsing after allogeneic bone marrow transplant (BMT) were treated with leukocyte transfusions from the original marrow donor (sibling, n = 9; volunteer unrelated, n = 5). The relapse was defined at the molecular level in two cases, cytogenetically in five cases and hematologically in seven cases. Ten patients responded, seven of seven patients with cytogenetic/molecular relapse compared with three of seven with hematologic relapse (P < .03). All five recipients of cells from unrelated donors responded. Eight of the 10 responders have achieved polymerase chain reaction-negative status and this persisted in three patients for more than 2 years; no responder has shown sign of relapse. Reversible marrow aplasia occurred in two patients, both treated in hematologic relapse. Severe graft-versus-host disease occurred in four patients and was fatal in one. We confirm previous reports that donor leukocyte transfusions are effective in the management of CML in relapse after BMT. In this series, therapeutic intervention before the onset of hematologic relapse was associated with an increased likelihood of response and no marrow aplasia.
Constraint-Based Question Answering with Knowledge Graph

WebQuestions and SimpleQuestions are two benchmark data-sets commonly used in recent knowledge-based question answering (KBQA) work. Most questions in them are ‘simple’ questions which can be answered based on a single relation in the knowledge base. Such data-sets lack the capability of evaluating KBQA systems on complicated questions. Motivated by this issue, we release a new data-set, namely ComplexQuestions, aiming to measure the quality of KBQA systems on ‘multi-constraint’ questions which require multiple knowledge base relations to get the answer. Beside, we propose a novel systematic KBQA approach to solve multi-constraint questions. Compared to state-of-the-art methods, our approach not only obtains comparable results on the two existing benchmark data-sets, but also achieves significant improvements on the ComplexQuestions.
Modeling individual differences in text reading fluency: a different pattern of predictors for typically developing and dyslexic readers

This study was aimed at predicting individual differences in text reading fluency. The basic proposal included two factors, i.e., the ability to decode letter strings (measured by discrete pseudo-word reading) and integration of the various sub-components involved in reading (measured by Rapid Automatized Naming, RAN). Subsequently, a third factor was added to the model, i.e., naming of discrete digits. In order to use homogeneous measures, all contributing variables considered the entire processing of the item, including pronunciation time. The model, which was based on commonality analysis, was applied to data from a group of 43 typically developing readers (11- to 13-year-olds) and a group of 25 chronologically matched dyslexic children. In typically developing readers, both orthographic decoding and integration of reading sub-components contributed significantly to the overall prediction of text reading fluency. The model prediction was higher (from ca. 37 to 52% of the explained variance) when we included the naming of discrete digits variable, which had a suppressive effect on pseudo-word reading. In the dyslexic readers, the variance explained by the two-factor model was high (69%) and did not change when the third factor was added. The lack of a suppression effect was likely due to the prominent individual differences in poor orthographic decoding of the dyslexic children. Analyses on data from both groups of children were replicated by using patches of colors as stimuli (both in the RAN task and in the discrete naming task) obtaining similar results. We conclude that it is possible to predict much of the variance in text-reading fluency using basic processes, such as orthographic decoding and integration of reading sub-components, even without taking into consideration higher-order linguistic factors such as lexical, semantic and contextual abilities. The approach validity of using proximal vs. distal causes to predict reading fluency is discussed.
Directive functions in intra-corporate cross-border email interaction

Alatalo, Pirjo Directive Functions in Intra-corporate Cross-border Email Interaction Jyvaskyla: University of Jyvaskyla, 2006, 470 p. (Jyvaskyla Studies in Humanities ISSN 1459-4331; 54) ISBN 951-39-2531-5 Finnish Summary Diss. This dissertation examines directive language use in English-language crossborder email interaction within a multinational company. Directivity is approached as a social, interactional and linguistic phenomenon in the participants’ sequences of email message initiations and responses. The contextual analysis focuses on 147 emails appearing in different message chains initiated by emails conveying a request for action. The study investigates how directives are realized lexico-grammatically and which contextual functions the diverse manifestations serve in different messages. The study also aims to find out how the interactants’ roles are established, maintained and re-established through different directive realizations, and how different participants are linguistically engaged in the on-going sequences of interactions. A transmethodological approach is used to analyze the email interaction. The linguistic analysis draws from a functionaldialogic approach and the intaractants’ directive behaviour is analyzed through the lens of the grammatical systems of mood and modulation within the interpersonal metafunction. Theoretically, the study aims to test the applicability of and develop two functional networks suggested by previous research. The findings showed that a full variety of congruent and incongruent mood selections were used in realizing directive functions. The two functional networks contributed to identifying, describing, and explaining different contextually nuanced directive functions. The lexico-grammatical realizations conveying the directive functions varied in their functions in different messages and, therefore, it was difficult to pinpoint distinct generalizable tendencies in the use of the mood structures. The in-depth contextual analysis of the nuanced directive functions showed that the identification, description, and interpretation of the different directive functions contributed to positioning the participants interactionally in dynamically shifting roles in the email sequences of initiations and responses. In sum, the functional-dialogic framework used in analyzing directive functions and examining role assignment and role positioning has introduced a new and challenging angle to analyzing naturally occurring email interaction in the business domain.
C-Terminal Truncation of NR2A Subunits Impairs Synaptic But Not Extrasynaptic Localization of NMDA Receptors

NMDA receptors interact via the extended intracellular C-terminal domain of the NR2 subunits with constituents of the postsynaptic density for purposes of retention, clustering, and functional regulation at central excitatory synapses. To examine the role of the C-terminal domain of NR2A in the synaptic localization and function of NR2A-containing NMDA receptors in hippocampal Schaffer collateral–CA1 pyramidal cell synapses, we analyzed mice which express NR2A only in its C-terminally truncated form. In CA1 cell somata, the levels, activation, and deactivation kinetics of extrasynaptic NMDA receptor channels were comparable in wild-type and mutant NR2AΔC/ΔCmice. At CA1 cell synapses, however, the truncated receptors were less concentrated than their full-length counterparts, as indicated by immunodetection in cultured neurons, synaptosomes, and postsynaptic densities. In the mutant, the NMDA component of evoked EPSCs was reduced in a developmentally progressing manner and was even more reduced in miniature EPSCs (mEPSCs) elicited by spontaneous glutamate release. Moreover, pharmacologically isolated NMDA currents evoked by synaptic stimulation had longer latencies and displayed slower rise and decay times, even in the presence of an NR2B-specific antagonist. These data strongly suggest that the C-terminal domain of NR2A subunits is important for the precise synaptic arrangement of NMDA receptors.