Miracle-dz/UniFAR-FTUs huggingface dataset:
Female Adolescent Sexuality

Abstract In this paper, I explore the resonance between experiences that are labeled “sexual problems” among adult women and adolescent girls' normative descriptions of their sexual experiences. Noting that female adolescent sexual dysfunction is an oxymoron, I review the feminist phenomenological research on female adolescent sexuality to support this claim. This review demonstrates and underscores the ways in which becoming sexual as an adolescent girl within the confines and constructs of patriarchy lays the groundwork for the kinds of “sexual problems” that are most evident in the female adult population. A developmental perspective on female sexuality is suggested as a way to support and extend the New View of Women's Sexual Problems.
Effects of treatment by laser-assisted uvuloplasty on sleep energy expenditure in obstructive sleep apnea patients.

The purpose of this study was to evaluate the effect of successful laser-assisted uvulopalatoplasty (LAUP) on sleep energy expenditure (EE) in obstructive sleep apnea syndrome (OSAS) patients. Fifteen healthy subjects (group I) and 25 patients with moderately severe or severe OSAS (group II) proven by overnight sleep study and who wanted LAUP were enrolled. During the night of the sleep studies, EE was measured with a metabolic cart (indirect calorimetry with canopy), including basal metabolic rate (BMR), mean sleep EE, lowest sleep EE, ratios of mean sleep EE/BMR, and lowest sleep EE/BMR. For the OSAS patients, a second sleep study with EE measurement was performed 3 months after LAUP. Based on this assessment of their sleep architecture, they were divided into 2 groups: responders (group IIa) and nonresponders (group IIb). The mean sleep EE, the ratio of mean sleep EE/BMR and lowest EE/BMR were significantly higher in group II than group I. After LAUP in group II, 6 patients were found to be responders (group IIa) and 19 patients were nonresponders (group IIb). Group IIa had decreased mean sleep EE, ratios of mean sleep EE/BMR, and lowest sleeping EE/BMR after LAUP than before LAUP compared with no significant changes in group IIb after LAUP. In conclusion, there is increased sleep EE in moderately severe OSAS patients when compared with normal controls. LAUP, when effective in reversing the sleep abnormalities, also normalizes the sleep EE. If it does not adequately treat the OSAS, however, the sleep EE remains abnormal.
Amiodarone for the prevention of sudden cardiac death: a meta-analysis of randomized controlled trials.

AIMS Not all patients at risk for sudden cardiac death (SCD) are eligible for, or have access to implantable cardioverter defibrillator (ICD) implantation. There are conflicting data regarding the efficacy and safety of amiodarone for the prevention of SCD. METHODS AND RESULTS We conducted a meta-analysis of all randomized controlled trials examining the use of amiodarone vs. placebo/control for the prevention of SCD. We identified 15 trials, which randomized 8522 patients to amiodarone or placebo/control. Amiodarone decreased the incidence of SCD [7.1 vs. 9.7%; OR 0.71 (0.61-0.84), P < 0.001] and cardiovascular death (CVD) [14.0 vs. 16.3%; OR 0.82 (0.71-0.94), P = 0.004]. There was a 1.5% absolute risk reduction in all-cause mortality which did not meet statistical significance (P = 0.093). Amiodarone therapy increased the risk of pulmonary [2.9 vs. 1.5%; OR 1.97, (1.27-3.04), P = 0.002], and thyroid [3.6 vs. 0.4%; OR 5.68, (2.94-10.98), P < 0.001] toxicity. CONCLUSION Amiodarone reduces the risk of SCD by 29% and CVD by 18%, and therefore, represents a viable alternative in patients who are not eligible for or who do not have access to ICD therapy for the prevention of SCD. However, amiodarone therapy is neutral with respect to all-cause mortality and is associated with a two- and five-fold increased risk of pulmonary and thyroid toxicity.
Serum inhibin concentration in dogs with adrenal gland disease and in healthy dogs.

BACKGROUND Studies in humans identified the synthesis and secretion of inhibin from adrenocortical tumors, but not pheochromocytoma (PHEO). Inhibin has not been examined in dogs as a serum biomarker for adrenal gland tumors. OBJECTIVE To determine serum inhibin concentration in dogs with adrenal gland disease and in healthy dogs. ANIMALS Forty-eight neutered dogs with adrenal disease including pituitary-dependent hyperadrenocorticism (PDH, 17), adrenocortical tumor (18), and PHEO (13), and 41 healthy intact or neutered dogs. METHODS Prospective observational study. Dogs were diagnosed with PDH, adrenocortical tumor (hyperadrenocorticism or noncortisol secreting), or PHEO based on clinical signs, endocrine function tests, abdominal ultrasound examination, and histopathology. Inhibin concentration was measured by radioimmunoassay in serum before and after ACTH stimulation, and before and after treatment. RESULTS In neutered dogs, median inhibin concentration was significantly higher in dogs with adrenocortical tumors (0.82 ng/mL) and PDH (0.16 ng/mL) than in dogs with PHEO and healthy dogs (both undetectable). Median inhibin concentration was significantly higher in dogs with adrenocortical tumors than in those with PDH and decreased after adrenalectomy. Median inhibin concentration was significantly higher in intact than in neutered healthy dogs and was similar in pre- and post-ACTH stimulation. Sensitivity, specificity, and accuracy of serum inhibin concentration for identifying an adrenal tumor as a PHEO were 100, 88.9, and 93.6%, respectively. CONCLUSIONS AND CLINICAL IMPORTANCE Adrenocortical tumors and PDH but not PHEOs are associated with increased serum inhibin concentration; undetectable inhibin is highly supportive of PHEO in neutered dogs with adrenal tumors.
What Works for Parent Involvement Programs for Adolescents: Lessons from Experimental Evaluations of Social Interventions. Fact Sheet. Publication #2009-48.

Adopting healthy and positive behaviors and avoiding risky ones are key developmental tasks of adolescence. Parents can play an important role in helping their adolescent children acquire or strengthen the behaviors, skills, attitudes, and motivation that promote physical and mental health and overall wellbeing. Recognizing this, a variety of programs and interventions seek to engage parents in efforts to achieve one or more outcomes for their adolescents: academic achievement; a reduction in internalizing behaviors such as depression and anxiety, or in disruptive or delinquent behaviors; a reduction or avoidance of substance use; avoidance of sexual risk-taking; and achieving/maintaining health and fitness.
Applying Ajzen's Theory of Planned Behavior to a Study of Online Course Adoption in Public Relations Education.

APPLYING AJZEN'S THEORY OF PLANNED BEHAVIOR TO A STUDY OF ONLINE COURSE ADOPTION IN PUBLIC RELATIONS EDUCATION Ann Peru Knabe, B.A, M.A., APR Marquette University, 2012 This study used Icek Ajzen’s Theory of Planned Behavior to research public relations faculty intentions of teaching online. All of the main predictor variables (Subjective Norms, Attitude toward the Act and Perceived Behavioral Control) were statistically significant at varying degrees in predicting intent to teach public relations online. Of the three, Subjective Norms was found to be the strongest predictor of Intention. Collectively, Subjective Norms, Attitude toward the Act and Perceived Behavioral Control explained 49% of the variance in intent to teach a public relations course online. Subsequent tests, however, revealed a poor model fit when the Theory of Planned Behavior is applied to faculty intentions of teaching public relations online. There were no significant relationships between the demographic variables age, gender and past experience teaching public relations and intentions to teach a public relations course online. Additional analysis revealed a crossover effect, a relationship between Attitude toward the Act and Subjective Norms.
The assessment of accuracy and reproducibility of cephalometric analyses using Computer-Assisted Simulation System for Orthognathic Surgery ( CASSOS ) software

Cephalometric analyses using computer software have more advantages than manual analyses. However, the software should be evaluated for the accuracy and reproducibility before it can be used. The aims of the present study were: 1) to compare the differences in accuracy and precision between utilizing scanned images and soft copy images with the software 2) to assess the reproducibility of software and manual cephalometric analyses. Fifteen cephalograms were selected randomly from the Record Unit, Hospital Universiti Sains Malaysia. All films had 10 fiducial points marked and were scanned at 75 dots per inch (dpi) and 300 dpi. Manual and digital measurements were compared to obtain magnification factors. Seven digital x-ray images of a caliper were taken. The mean differences were measured between the fixed caliper measurement and digital measurements. Subsequently, 37 cephalograms were traced manually and digitally with Computer-Assisted Simulation System for Orthognathic Surgery (CASSOS) software to assess its accuracy and reproducibility after applying the obtained magnification factor. Steiner analysis was utilized and T tests were used to evaluate the mean difference. P<0.01 was considered significant. The magnification factors of 300dpi and 75dpi for both horizontal and vertical measurements were 0.50 and 0.95 respectively, while magnification factor for softcopy image measurements was 0.89. Cephalometric comparisons between original and digital images showed statistically significant differences for several variables but the mean differences were clinically insignificant. Although some distortion was noted, it was clinically acceptable after correction of the enlarged images with magnification factors. The reproducibility of CASSOS is excellent and as good as other commercially available cephalometric software.
A Survey of App Store Analysis for Software Engineering

App Store Analysis studies information about applications obtained from app stores. App stores provide a wealth of information derived from users that would not exist had the applications been distributed via previous software deployment methods. App Store Analysis combines this non-technical information with technical information to learn trends and behaviours within these forms of software repositories. Findings from App Store Analysis have a direct and actionable impact on the software teams that develop software for app stores, and have led to techniques for requirements engineering, release planning, software design, security and testing. This survey describes and compares the areas of research that have been explored thus far, drawing out common aspects, trends and directions future research should take to address open problems and challenges.
Türkiye’de cep telefonu cihazı pazarında marka sadakati için bir model denemesi (A model of brand loyalty in Turkish cellular phone market)

Yapisal Esitlik Modelleri araciligiyla marka sadakatine etki eden unsurlarin belirlenmeye calisildigi bu makalede marka sadakati, guven, musteri memnuniyeti, algilanan urun degeri, algilanan kalite, musteri beklentileri ve marka imaji latent degiskenleri icin olcme modeli kurulduktan sonra bu latent degiskenler arasindaki esanli iliskiler belirlenmis ve Turkiye’de cep telefonu cihazi pazarinda, cep telefonu markalari icin bir marka sadakati modeli olusturulmustur. 770 cep telefonu kullanicisina (universite ogrencisine) uygulanan anketin verileri kullanilarak, modeldeki degiskenler arasindaki iliskiler test edilmis ve kuramsal olarak ortaya konulan; musteri memnuniyetinin, guveninin ve algilanan urun kalitesinin sadakat ustunde; guvenin ve algilanan degerin musteri memnuniyeti ustunde; marka imaji, algilanan kalite ve urunden beklentilerin algilanan deger ustunde; marka imaji ve algilanan kalitenin guvenin ustunde dogrudan etkileri bulunmaktadir hipotezleri desteklenmistir.
Metalworking Fluid-Related Aerosols in Machining Plants

Respiratory problems are observed in machinists using soluble metalworking fluid (MWF). Evidences suggest that these problems could be related to the aerosolized microorganisms and their byproducts from MWF. To establish MWF aerosol exposure thresholds and to better understand their effect on human health, these aerosols must be fully characterized. This article evaluates airborne microorganisms and aerosols from soluble MWF in the working environment. Air quality parameters (endotoxin levels, culturable airborne microorganisms, fluid mist, inhalable dust and air exchange rates) were evaluated at 44 sites, in 25 shops in Quebec, Canada. Microorganism concentrations were also measured in MWF. Culturable airborne bacteria concentrations were low, ranging from 1.2 × 101 to 1.5 × 103 CFU (colony forming units) m− 3, even for metalworking fluid highly contaminated by bacteria (up to 2.4 × 109 CFU mL− 1). Inhalable dust varied between < 0.1 to 2.6 mg m− 3, while air exchange rates were mostly below the standard (4 h− 1) for this type of workplace, between 0.6 to 14.2 h− 1. Only nine of 44 sites respected the suggested minimum value for air exchange rates. Fluid mist ranged from 0.02 to 0.89 mg m− 3, which is below the threshold limit value (TLV) (ACGIH) of 5 mg m− 3. Airborne endotoxin concentrations ranged from undetectable to 183 EU m− 3 (endotoxin units), showing no correlation with airborne microorganisms or inhalable dust. Most workstations respected the suggested minimum values for fluid mist and showed low concentrations of airborne endotoxin, culturable microorganisms and inhalable dust despite fluid contamination, even when air exchange rates were below the recommendations. Airborne Pseudomonas pseudoalcaligenes was recovered from many sites at significant concentrations. Health-associated risks following exposure to this microorganism should be further investigated.
Role of Escherichia coli histone-like nucleoid-structuring protein in bacterial metabolism and stress response--identification of targets by two-dimensional electrophoresis.

The histone-like nucleoid-structuring protein, H-NS, is a major bacterial chromatin component which influences DNA structure and gene expression. Mutations in hns, the structural gene of H-NS protein, have been shown to result in highly pleiotropic effects in Escherichia coli cells. In this study, we have initiated an index of the proteins whose synthesis is, directly or indirectly regulated by H-NS. Using two-dimensional gel electrophoresis, we have examined the global changes in gene expression which occured in an hns background compared with its wild-type parent. In addition, we analysed the effects of mutations in two other genes i.e. lrp and pta, which are also involved in global regulatory pathways. Although these comparative analyses revealed several common differences, thus suggesting possible interactions between these regulatory mechanisms, i.e. H-NS, Lrp (leucine-responsive regulatory protein) and acetylphosphate, the most extensive modifications occurred in an hns mutant. Among the polypeptides whose level of synthesis was specifically altered in an hns mutant, several corresponded to H-NS targets previously identified by classical selection methods. Moreover, the present study allows us to characterize several H-NS targets, which were identified either by comparison with the E. coli two-dimensional reference maps or by microsequencing procedure. Many of these newly identified polypeptides are involved in adaptation of E. coli cells to environmental challenges, and one of them could be involved in bacterial virulence. Finally, synthesis of several proteins belonging to the heat-shock regulon, more particularly molecular chaperones, was induced in an hns mutant.
Immunoconglutinin and Complement Studies in Congenital Nephrotic Syndrome and Nephritis of Henoch-Schönlein Purpura in Children

Evidence of complement activation in 6 children with congenital nephrotic syndrome and 9 children with nephritis associated with Henoch-Schönlein purpura was sought by estimating the concentration and by immunoelectrophoretic analysis of the complement component C3, and by immunoconglutinin titration (IK: an autoantibody to reacted complement components). IK and quantitative C3 levels did not differ significantly from control values in either disease; in vivo C3 conversion was not detected in plasma from congenital nephrotic patients, but was present in 2 of 9 patients with Henoch-Schönlein nephritis. The data do not provide consistent evidence of complement involvement in either disease.
[Variations in the use of hospital resources in treating patients with chronic obstructive pulmonary disease].

AIM To analyze factors associated with the length of stay and pharmaceuticals expense for patients admitted with chronic obstructive pulmonary disease (COPD) and to evaluate whether treatment by different physicians means greater or less use of hospital resources. METHODS We retrospectively studied a cohort of 1033 COPD patients admitted to the Hospital de Mataró, Catalonia, Spain, during the years 1996 through 1998 in order to analyze factors associated with length of stay and pharmaceuticals use. We used the Minimum Basic Data Set, laboratory databases, and pharmacy single-dose database. We also analyzed the differences among patients treated by different physicians and developed multiple linear regression models to evaluate differences in treatment between one physician and another. RESULTS The length of stay increased with patient age, the number of times admitted, the presence of atrial fibrillation or respiratory insufficiency, ventilatory alterations, chronicity, a forced expiratory volume in 1 second less than 50% of predicted, and treatment by certain physicians. Medication costs showed a similar pattern. Although the characteristics of patients treated by different physicians were quite homogeneous, the median length of stay varied from 9 to 11 days depending on the physician, while the median cost for medication varied from;43.62 to;54.39 (from $41.07 to $51.21). After removing the effects of several covariables by multiple regression analysis, an effect of physician persisted. CONCLUSIONS Significant differences in length of hospital stay and consumption of pharmaceuticals are related to attending physician and continue to have an important effect after controlling for the differences in the severity of patient status.
Attenuation correction for whole-body PET imaging using automated fuzzy clustering-based segmentation method

Segmented-based attenuation correction is now a widely accepted technique to reduce noise contribution of measured attenuation correction. In this paper, we present a new method for segmenting transmission images in positron emission tomography. This reduces the noise on the correction maps while still correcting for differing attenuation coefficients of specific tissues. Based on the Fuzzy C-Means (FCM) algorithm, the method segments the PET transmission images into a given number of clusters to extract specific areas of differing attenuation such as air, the lungs and soft tissue, preceded by a median filtering procedure. The reconstructed transmission image voxels are therefore segmented into populations of uniform attenuation based on the human anatomy. The clustering procedure starts with an over-specified number of clusters followed by a merging process to group clusters with similar properties and remove some undesired substructures using anatomical knowledge.
Subjectivity as a site of struggle: refusing neoliberalism?

This paper extends the author’s previous enquiries and discussions of governmentality and neoliberal policy technologies in a number of ways. The paper explores the specificity and generality of performativity as a particular contemporary mode of power relations. It addresses our own imbrication in the politics of performative truths, through our ordinary everyday life and work. The paper is about the here and now, us, you and me, and who we are in neoliberal education. It draws upon and considers a set of ongoing email exchanges with a small group of teachers who are struggling with performativity. It enters the ‘theoretical silence’ of governmentality studies around the issues of resistance and contestation. Above all, the paper attempts to articulate the risks of refusal through Foucault’s notion of fearless speech or truth-telling (parrhesia).
Ratio of anogenital warts between different anatomical sites in homosexual and heterosexual individuals in Australia, 2002–2013: implications for susceptibility of different anatomical sites to genital warts

SUMMARY There is little known regarding the transmissibility of human papillomavirus (HPV) between different sites in men who have sex with men (MSM) and heterosexual individuals. We conducted a retrospective analysis investigating all new patients attending the Melbourne Sexual Health Centre in Australia between 2002 and 2013. We describe the prevalence and ratio of the first episode of anogenital warts in MSM and heterosexual males and females. The proportion of new MSM clients with anal and penile warts was 4·0% (362/8978) and 1·6% (141/8978), respectively; which gave an anal-to-penile wart ratio of 1:2·6. About 13·7% (1656/12112) of heterosexual males had penile warts and 10·0% (1121/11166) of females had vulval warts, which yielded a penile-to-vulval wart ratio of 1:0·7. Penile–anal transmission has a higher ratio than penile–vulval transmission, suggesting that the anal epithelium may be more susceptible to HPV infection than the vulval epithelium in females; these ratios are important in modelling the control of HPV in MSM.
[Energy expenditure of healthy Brazilian adults: a comparison of methods].

UNLABELLED There are many available methods to measure the human energy consumption. Due to the high cost and small number of laboratories able to perform it, the direct calorimetry and doubly labeled water technique are rarely used to measure the energy expenditure. As consequence, there is an increase use of the indirect calorimetry and bioelectrical impedance analysis methods by researchers and predictive equations by physicians to calculate the total energy requirements in research and in clinic. OBJECTIVE To evaluate the basal energy expenditure (GEB) and total energy expenditure (GET) of healthy subjects comparing results of indirect calorimetry (CI), bioelectrical impedance analysis (BIA) and predictive equations such as estimated energy requirements (EER), Fleish, FAO/WHO/UNU 1985 and 2001. MATERIAL AND METHODS It was evaluated the energy expenditure in 81 subjects of both gender by CI and BIA. Of these, the GEB by predictive equations FAO/WHO/UNU 1985 and 2001 and the GET by EER, Fleisch and FAO/WHO/UNU 1985 and 2001 were calculated. The data was analyzed with the software Sigma Stat for Windows version 2.03 and Dunn's test was used for comparison of mean obtained with methods and equations (p < 0.05). RESULTS It was verified that 60.5% of the participants were men. The majority of subjects were eutrofic. BIA showed significant differences between men and women. The differences between the values of GEB, obtained by BIA and CI, were statistically significant only for women (p < 0.05) with an underestimation of the GEB results obtained by BIA in relation to those obtained by CI. Significant difference was found between the predictive equations and CI for both sexes, also demonstrating an underestimation of the equations in relation to CI. It was observed an overestimation of GET with the predictive equations of FAO/WHO/UNU/85 and 2001 in relation to EER and Fleisch for both sexes. CONCLUSION The estimation of GEB can be carried out by both BIA and CI, although BIA must be used with criteria since it underestimates in a significant way for women. In relation to the predictive equations, overestimation can develop positive energy balance in populations with risks for overweight and obesity. Thus, it is necessary comparisons to identify the limitations of each method.