Miracle-dz/UniFAR-FTUs huggingface dataset:
Transition-metal-doped group-IV monochalcogenides: a combination of two-dimensional triferroics and diluted magnetic semiconductors

We report the first-principles evidence of a series of two-dimensional triferroics (ferromagnetic + ferroelectric + ferroelastic), which can be obtained by doping transition-metal ions in group-IV monochalcogenide (SnS, SnSe, GeS, GeSe) monolayers, noting that a ferromagnetic Fe-doped SnS2 monolayer has recently been realized (Li B et al 2017 Nat. Commun. 8 1958). The ferroelectricity, ferroelasticity and ferromagnetism can be coupled and the magnetization direction may be switched upon ferroelectric/ferroelastic switching, rendering electrical writing + magnetic reading possible. They can be also two-dimensional half-metals or diluted magnetic semiconductors, where p/n channels or even multiferroic tunneling junctions can be designed by variation in doping and incorporated into a monolayer wafer.
Complement Factor H Variant Y 402 H Is a Major Risk Determinant for Geographic Atrophy and Choroidal Neovascularization in Smokers and Nonsmokers

RESULTS. The frequencies of the C allele and CC genotype were significantly higher in cases than in controls. In comparison to the TT genotype, the odds ratios for AMD associated with the CT and CC genotypes were 3.1 (CI 2.0 – 4.6) and 6.3 (CI 3.8 –10.4), respectively. The results were similar in subgroup analyses confined to cases with GA or CNV. The findings were also similar for subgroup analyses restricted to subjects who had never smoked, moderate smokers, or heavier smokers ( 20 pack years of smoking). Heavier smokers with the CC genotype may be particularly at risk. The frequency of the CC genotype did not differ significantly between cases with and without a family history of AMD. There was no evidence that genotype had any influence on age at onset of disease.
Epidemiology of Hospitalized Burn Patients in Shandong Province: 2001–2005

The aim of the article was to describe the epidemiology of burn injuries requiring hospitalization at Shandong Provincial Hospital and to provide information necessary for the design and implementation of effective prevention programs. The records of patients with burn injury admitted to our burn unit over a 5-year period (1 January 2001 to 31 December 2005) were reviewed. Medical record review provided basic demographic information and details on the extent of injury, time of day burns occurred, month of admission, cause of burn, accident site, first aid, number of operations, length of hospital stay, and mortality. There was no trend in annual admissions. The male-to-female ratio was 3:1. The age distribution of burn patients showed peaks occurring at the age groups of 0 to 10 and 20 to 30 years. Over the course of a day, burn injuries occurred most frequently from 1700 to 1900 hours. Scalds accounted for 45.23% (502) of the 1110 patients, and flame burns accounted for 42.33% (471). Only 29% of all patients received proper first aid with cool water or burn cream. The average length of hospital stay was 22 days. Children under 10 years and adults between 20 and 30 years of age are the most susceptible populations, and first aid is performed poorly in Shandong Province. Burn prevention and first aid education campaigns should be launched to encourage safe lifestyle and work habits.
Genome-wide Analysis of Alternative Splicing in An Inbred Cabbage (Brassica oleracea L.) Line ‘HO’ in Response to Heat Stress

Introduction: High-throughput RNA sequencing (RNA-Seq) studies demonstrate that Alter-native Splicing (AS) is a widespread mechanism that enhances transcriptome diversity, particularly in plants exposed to environmental stress. In an attempt to determine the transcriptome and AS patterns of cabbage inbred line “HO” under Heat Stress (HS), RNA-Seq was carried out using HS-treated and con-trol samples. Genome-wide analysis indicated that AS is differentially regulated in response to HS. The number of AS events markedly increased in HS-treated samples compared to the control. Conclusion: We identified 1,864 genes, including Heat shock transcription factor (Hsf) and heat shock protein (Hsp) genes, that exhibited >4-fold changes in expression upon exposure to HS. The enriched Gene Ontology (GO) terms of the 1,864 genes included ‘response to stress/abiotic stimulus/chemical stimulus’, among, which the genes most highly induced by HS encode small Hsps and Hsf proteins. The heat-induced genes also showed an increased number of AS events under HS conditions. In addi-tion, the distribution of AS types was altered under HS conditions, as the level of Intron Retention (IR) decreased, whereas other types of AS increased, under these conditions. Severe HS-induced AS was al-so observed in Hsfs and Hsps, which play crucial roles in regulating heat tolerance. Our results support the notion that AS of HS-related genes, such as HsfA2 and HsfB2a, are important for heat stress adapta-tion in cabbage.
Representing the dosimetric impact of deformable image registration errors

Deformable image registration (DIR) is emerging as a tool in radiation therapy for calculating the cumulative dose distribution across multiple fractions of treatment. Unfortunately, due to the variable nature of DIR algorithms and dependence of performance on image quality, registration errors can result in dose accumulation errors. In this study, landmarked images were used to characterize the DIR error throughout an image space and determine its impact on dosimetric analysis. Ten thoracic 4DCT images with 300 landmarks per image study matching the end-inspiration and end-expiration phases were obtained from ‘dir-labs’. DIR was performed using commercial software MIM Maestro. The range of dose uncertainty (RDU) was calculated at each landmark pair as the maximum and minimum of the doses within a sphere around the landmark in the end-expiration phase. The radius of the sphere was defined by a measure of DIR error which included either the actual DIR error, mean DIR error per study, constant errors of 2 or 5 mm, inverse consistency error, transitivity error or the distance discordance metric (DDM). The RDUs were evaluated using the magnitude of dose uncertainty (MDU) and inclusion rate (IR) of actual error lying within the predicted RDU. The RDU was calculated for 300 landmark pairs on each 4DCT study for all measures of DIR error. The most representative RDU was determined using the actual DIR error with a MDU of 2.5 Gy and IR of 97%. Across all other measures of DIR error, the DDM was most predictive with a MDU of 2.5 Gy and IR of 86%, closest to the actual DIR error. The proposed method represents the range of dosimetric uncertainty of DIR error using either landmarks at specific voxels or measures of registration accuracy throughout the volume.
Assessment of the Causes of Indicated Defects in Forgings

The article deals with analysis of defects indicated in large forgings in the course of ultrasonic testing. The aim of the metallographic analysis of the defects was to establish whether and to what extent casting or filling powders took part in their emergence that had been used when casting the ingots from which the forgings were made.
Toxicity of glyphosate‐based pesticides to four North American frog species

Gyphosate‐basedherbicides are among the most widely used pesticides in the world. We compared the acute toxicity of the glyphosate end‐use formulation Roundup Original® to four North American amphibian species (Rana clamitans, R. pipiens, R. sylvatica, and Bufo americanus) and the toxicity of glyphosate technical, the polyethoxylated tallowamine surfactant (POEA) commonly used in glyphosate‐based herbicides, and five newer glyphosate formulations to R. clamitans. For R. clamitans, acute toxicity values in order of decreasing toxicity were POEA > Roundup Original > Roundup Transorb® > Glyfos AU®; no significant acute toxicity was observed with glyphosate technical material or the glyphosate formulations Roundup Biactive®, Touchdown®, or Glyfos BIO®. Comparisons between the four amphibian species showed that the toxicity of Roundup Original varied with species and developmental stage. Rana pipiens tadpoles chronically exposed to environmentally relevant concentrations of POEA or glyphosate formulations containing POEA showed decreased snout‐vent length at metamorphosis and increased time to metamorphosis, tail damage, and gonadal abnormalities. These effects may be caused, in some part, by disruption of hormone signaling, because thyroid hormone receptor β mRNA transcript levels were elevated by exposure to formulations containing glyphosate and POEA. Taken together, the data suggest that surfactant composition must be considered in the evaluation of toxicity of glyphosate‐based herbicides.
EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002 Geneva, Switzerland. Consensus statement (long version).

CHAIRPERSONS & INVITED SPEAKERS: Alfredo Alberti, Italy; Miriam Alter, USA; Yves Benhamou, France; Paolo Bonanni, Italy; Feruccio Bonino, Italy; Flavia Bortolotti, Italy; Jordi Bruix, Spain; Maurizia Brunetto, Italy; Massimo Colombo, Italy; Graham Cooksley, Australia; Antonia Craxi, Italy; Valeer Desmet, Belgium; Philippe Duclos, Switzerland; Geoffrey Dusheiko, UK; Rafael Esteban, Spain; Patrizia Farci, Italy; Giovanna Fattovich, Italy; Carlo Ferrari, Italy; Stephanos Hadziyannis, Greece; Jenny Heathcote, Canada; Jay Hoofnagle, USA; Yun-Fan Liaw, Taiwan; Stephen Locarnini, Australia; Michael Manns, Germany; Patrick Marcellin, France; Pem Namgyal, Switzerland; Nikolai Naoumov, UK; Jean-Michel Pawlotsky, France; Robert Perrillo, USA; Stanislas Pol, France; Patrizia Pontisso, Italy; Giovanni Raimondo, Italy; Mario Rizzetto, Italy; Michael Roggendorf, Germany; Didier Samuel, France; Solko Schalm, The Netherlands; Daniel Shouval, Israel; Howard Thomas, UK; Christian Trépo, France; Pierre Van Damme, Belgium; Hans Will, Germany; Theresa Wright, USA; Stephan Zeuzem, Germany; Fabien Zoulim, France
Social personalized ranking recommendation algorithm by trust

The problem with previous studies of social personalized ranking (SPR) algorithms is that they simply integrated the user's social network information into their model, without taking into account the transmission of social trust networks between users. To solve this problem, a new social personalized ranking recommendation algorithm (TrustSPR) based on ListRank algorithm and the newest TrustMF algorithm is proposed, which aims to improve the performance of personalized ranking recommendation algorithm. Experimental results on a real-world dataset showed that the TrustSPR algorithm outperformed state-of-the-art SPR approachs over different evaluation metrics, and that the TrustSPR algorithm possesses good expansibility.
MultiNet: Multi-Modal Multi-Task Learning for Autonomous Driving

Autonomous driving requires operation in different behavioral modes ranging from lane following and intersection crossing to turning and stopping. However, most existing deep learning approaches to autonomous driving do not consider the behavioral mode in the training strategy. This paper describes a technique for learning multiple distinct behavioral modes in a single deep neural network through the use of multi-modal multi-task learning. We study the effectiveness of this approach, denoted MultiNet, using self-driving model cars for driving in unstructured environments such as sidewalks and unpaved roads. Using labeled data from over one hundred hours of driving our fleet of 1/10th scale model cars, we trained different neural networks to predict the steering angle and driving speed of the vehicle in different behavioral modes. We show that in each case, MultiNet networks outperform networks trained on individual modes while using a fraction of the total number of parameters.
Short-lived brominated hydrocarbons – observations in the source regions and the tropical tropopause layer

We conducted measurements of the five important short-lived organic bromine species in the marine boundary layer (MBL). Measurements were made in the Northern Hemisphere mid-latitudes (Sylt Island, North Sea) in June 2009 and in the tropical Western Pacific during the TransBrom ship campaign in October 2009. For the one-week time series on Sylt Island, mean mixing ratios of CHBr3, CH2Br2, CHBr2Cl and CH2BrCl were 2.0, 1.1, 0.2, 0.1 ppt, respectively. We found maxima of 5.8 and 1.6 ppt for the two main components CHBr3 and CH2Br2. Along the cruise track in the Western Pacific (between 41° N and 13° S) we measured mean mixing ratios of 0.9, 0.9, 0.2, 0.1 and 0.1 ppt for CHBr3, CH2Br2, CHBrCl2, CHBr2Cl and CH2BrCl. Air samples with coastal influence showed considerably higher mixing ratios than the samples with open ocean origin. Correlation analyses of the two data sets yielded strong linear relationships between the mixing ratios of four of the five species (except for CH2BrCl). Using a combined data set from the two campaigns and a comparison with the results from two former studies, rough estimates of the molar emission ratios between the correlated substances were: 9/1/0.35/0.35 for CHBr3/CH2Br2/CHBrCl2/CHBr2Cl. Additional measurements were made in the tropical tropopause layer (TTL) above Teresina (Brazil, 5° S) in June 2008, using balloon-borne cryogenic whole air sampling technique. Near the level of zero clear-sky net radiative heating (LZRH) at 14.8 km about 2.25 ppt organic bromine was bound to the five short-lived species, making up 13% of total organic bromine (17.82 ppt). CH2Br2 (1.45 ppt) and CHBr3 (0.56 ppt) accounted for 90% of the budget of short-lived compounds in that region. Near the tropopause (at 17.5 km) organic bromine from these substances was reduced to 1.35 ppt, with 1.07 and 0.12 ppt attributed to CH2Br2 and CHBr3, respectively.
Fixed-bed biomass pyrolysis: mechanisms and biochar production

The objective of this thesis is to gain a deeper understanding on the slow pyrolytic conversion of biomass in conditions similar to the ones present at industrial scale. The purpose of this is to contribute to two topics of signi cant relevance in the biomass thermochemical conversion community nowadays. Firstly, the need for further development of more detailed pyrolysis mechanisms, which account not only for chemical reactions pathways, but also for the in uence of transport phenomena on these chemical reactions, enhanced in conditions typical of industrial scale, due to bigger particle and bed sizes. Secondly, the use of slow pyrolysis for production of biochar, in particular, the understanding of how pyrolysis conditions may a ect biochar properties and consequently its behavior in soil. To this end, a technical-scale xed bed reactor has been built, together with a novel combination of on-line characterization techniques, to perform an exhaustive on-line evaluation of the pyrolysis process. These techniques include temperature measurements inside the bed, characterization of permanent gas composition with gas chromatography thermal conductivity detection (GC-TCD) and detection of uorescence emitting compounds with laser-induced uorescence spectroscopy (LIF). Di erentiation between primary pyrolysis and secondary reactions of primary volatiles has been achieved, thanks to the selective detection of targeted species, products of these secondary reactions. Investigation on the source and production enhancement mechanisms of these species has been also carried out. In a second stage, several characterization methodologies have been developed and applied to get a deep characterization of the solid product (biochar), from two perspectives: structural properties and potential behavior in soil. The objective is to establish clear relations to ”engineer” biochar, according to soil application demands and certication requirements. Besides, development of characterization techniques which may lead to a more complete evaluation and therefore better certi cation of this biochar has been considered, in particular for porosity characterization.
Design of a multi-carrier different chaos shift keying communication system in doubly selective fading channels

In this paper, a novel chaos modulation scheme, which combines code-shifted differential chaos shift keying (CS-DCSK) with orthogonal frequency division multiplexing (OFDM) is presented, namely OFDM-CS-DCSK. In the proposed scheme, the reference signal and the information bearing signal of CS-DCSK are firstly formed by Walsh code sequences, then different chips of the CS-DCSK signal are mapped onto different subcarriers of OFDM. Utilizing the characteristics of OFDM and CS-DCSK, the proposed scheme has robust performance over time-frequency doubly selective fading channel. In addition, the proposed system has low complexity because channel estimation, channel equalizer and the radio frequency (RF) delay circuits are not required at its receiver. By the computer simulations, bit error rate (BER) performances of the proposed scheme are compared with OFDM-DCSK and CS-DCSK under various channel parameters. Simulation results indicate that the proposed scheme has significant performance advantages over OFDM-DCSK and CS-DCSK in time-frequency doubly selective fading channel.
Application of 3D Printing for Smart Objects with Embedded Electronic Sensors and Systems

Applications of a 3D printing process are presented. This process integrates liquid-state printed components and interconnects with IC chips in all three dimensions, various orientations, and multiple printing layers to deliver personalized system-level functionalities. As an example application, a form-fitting glove is demonstrated with embedded programmable heater, temperature sensor, and the associated control electronics for thermotherapeutic treatment.
Evolutionary Patterns and Processes: Lessons from Ancient DNA

Abstract Ever since its emergence in 1984, the field of ancient DNA has struggled to overcome the challenges related to the decay of DNA molecules in the fossil record. With the recent development of high-throughput DNA sequencing technologies and molecular techniques tailored to ultra-damaged templates, it has now come of age, merging together approaches in phylogenomics, population genomics, epigenomics, and metagenomics. Leveraging on complete temporal sample series, ancient DNA provides direct access to the most important dimension in evolution—time, allowing a wealth of fundamental evolutionary processes to be addressed at unprecedented resolution. This review taps into the most recent findings in ancient DNA research to present analyses of ancient genomic and metagenomic data.
Gender bias in sentiment analysis

Purpose The purpose of this paper is to test if there are biases in lexical sentiment analysis accuracy between reviews authored by males and females. Design/methodology/approach This paper uses data sets of TripAdvisor reviews of hotels and restaurants in the UK written by UK residents to contrast the accuracy of lexical sentiment analysis for males and females. Findings Male sentiment is harder to detect because it is less explicit. There was no evidence that this problem could be solved by gender-specific lexical sentiment analysis. Research limitations/implications Only one lexical sentiment analysis algorithm was used. Practical implications Care should be taken when drawing conclusions about gender differences from automatic sentiment analysis results. When comparing opinions for product aspects that appeal differently to men and women, female sentiments are likely to be overrepresented, biasing the results. Originality/value This is the first evidence that lexical sentiment analysis is less able to detect the opinions of one gender than another.
A nationwide cross-sectional survey of pharmacy students on pharmacogenetic testing in The Netherlands.

AIM To benchmark knowledge and attitude of pharmacy students toward pharmacogenetics (PGx) and PGx testing and compare the results with practicing colleagues. METHODS All pharmacy students in The Netherlands were invited to participate in a web-based survey consisting of 28 questions. Out of the 824 invited students, 148 individuals (18.0%) completed the questionnaire. All responders believed in the concept of PGx and had high expectations toward PGx. The majority (96.6%) had received some form of education on PGx, but only 12.8% felt adequately informed. RESULTS When compared with practicing pharmacists, differences were observed in the use of information and feeling qualified to recommend PGx testing. CONCLUSION More education on PGx is required in the curriculum to fill the perceived knowledge gap among future pharmacists.
The Effect of Fluoride Varnish on Enamel Shear Bond Strength of Pit and Fissure Sealants.

PURPOSE The purpose of this study was to determine the effects of fluoride varnish on the enamel shear bond strength of pit and fissure sealants. METHODS Ninety-six teeth were divided into three duplicated test groups: sealant (S)/sealant thermocycle (ST) received Clinpro Sealant only; varnish sealant (VS)/varnish sealant thermocycle (VST) received five percent sodium fluoride (NaF) varnish plus sealant (VPS); and VPS/VPS thermocycle (VPST) received NaF, polish with Clinpro Prophy Paste, plus sealant. One set of each group (ST, VST, VPST) was thermocycled to represent aging, and one set (S, VS, PVS) was not. The shear bond strengths for the thermocycled groups and nonthermocycled groups were determined, and two-way analysis of variance tested the effects of thermocycling and varnish. RESULTS Thermocycling did not have a significant effect on the peak stresses of the groups (P=0.0552), so sets were combined. The peak stress for S/ST was significantly higher than for VS/VST (P<0.0001). The peak stress for VPS/VPST was significantly higher than for VS/VST (P<0.0001). The peak stress for S/ST was significantly higher than VPS/VPST (P=0.025). CONCLUSION Fluoride varnish applied immediately before pit and fissure sealant placement negatively affected the shear bond strength of the sealant. Mechanically cleaning a fluoride varnish-coated tooth with prophy paste did not provide pit and fissure sealant enamel shear bond strengths comparable to those of untreated enamel.
Anemia tolerance during normo‐, hypo‐, and hypervolemia

Restrictive intraoperative fluid management has been demonstrated to improve outcome of visceral and lung surgery in several studies. However, subsequent hypovolemia (HOV) may be accompanied by a decrease of anemia tolerance, resulting in increased transfusion needs. We therefore investigated the effect of volume status on anemia tolerance.