Miracle-dz/UniFAR-FTUs huggingface dataset:
Preferred-Habitat and Demand Factors in the Term Structure: Evidence from the Chinese Bond Market

Recent empirical studies suggest that demand and supply factors have important effects on bond yields. Both market segmentation and preferred habitat hypothesis are used to explain these demand and supply effects. In this paper, we use an affine preferred-habitat term structure model and the unique Chinese bond market data to study these two hypotheses. Chinese bond market is unique because there exists an official term structure of lending rates, set exogenously by the government, on preferred habitat investors' alternative investments of loans. We show that demands of both the preferred-habitat investors and the arbitrageurs affect bond yields and returns. Moreover, we find that the preferred-habitat investors' alternative investment opportunities have expected effect on bond yields and returns. We further show that the preferred-habitat and demand factors improve bond pricing and return predictability in a no-arbitrage term structure model. Variance decomposition analysis shows that the preferred-habitat factor explains an important part of bond yield variations.
Usefulness of sentinel lymph node biopsy for extramammary Paget disease

In the present study, we sequenced the RPL21 gene in a Chinese family and could not find any variant. However, we identified a recurrent mutation, c.26T>G (p.Leu9Arg), in the APCDD1 gene. The mutation p.Leu9Arg is located within the cleavage site of the APCDD1 protein which has been shown to be highly conserved during evolution among dog, horse, mouse and bat, and may be critical for the function of the protein.
Volunteers as tour guides: a stakeholder–agency theory case study†

The use of volunteer tour guides by commercial tour operators has attracted little scholarly attention. This paper presents a qualitative case study of a commercially organized tour led by volunteer tour guides, and explores how the guides' status as volunteers shaped experiences of tour customers. Analysis, underpinned by stakeholder–agency theory, highlighted a range of service delivery issues that emerged during the tour. Theoretical and applied implications are discussed, with particular reference to how tour operators might negotiate the vexed issue of managing service delivery quality in the context of tour services paid for by customers, yet delivered by volunteers. Further research is required to explore potential differences in the willingness of tour operators to invest in human resource development initiatives for paid versus volunteer tour guides, along with possible flow-on implications for tour guides' role performance and customer satisfaction.
Relationship between amniotic fluid and maternal blood nutrient levels

To study the relationships between amniotic fluid and maternal blood nutrient concentrations, we obtained amniotic fluid and blood samples simultaneously from 76 pregnant women at around 17 weeks gestation. Folate and vitamin B-12 levels were measured by microbiological assay and radioassay, respectively, and zinc, copper and iron levels by atomic absorption spectrophotometry. Mean concentrations of plasma and red blood cell (RBC) folate and plasma copper of the pregnant women were 38 (+/- 1, SD), 1,501 (+/- 374) nmol/L, and 32.7 (+/- 4.8) mumol/L, respectively, all of which were higher than those of healthy non-pregnant controls (p < 0.001). Mean concentrations of plasma vitamin B-12, zinc and iron levels and RBC zinc were 320 (+/- 130) pmol/L, 12.2 (+/- 2.3), 21.7 (+/- 6.1) and 177 (+/- 30) mumol/L and these were similar to those of non-pregnant controls. Amniotic fluid folate, zinc, copper and iron concentrations were 21 (+/- 13) nmol/L, 1.4 (+/- 0.6), 1.7 (+/- 0.6) and 6.8 (+/- 2.1) mumol/L, respectively, which were significantly lower than plasma levels (p < 0.001). However, this relationship was reversed for vitamin B-12 (650 +/- 420 pmol/L). Significant correlations were found between amniotic fluid and maternal plasma and RBC for folate, and between amniotic fluid and maternal plasma for vitamin B-12 (p < 0.001). No such correlations were observed for zinc, copper and iron. There was no correlation between amniotic fluid and/or blood nutrient concentrations and pregnancy outcome including birth weight of infants.
The Management of Blunt Fractures of the Thyroid Cartilage

Our experience with 20 cases of blunt fractures of the thyroid cartilage encountered over the last 15 years were reviewed. These injuries were classified into one of three categories: nondisplaced with minimal associated laryngeal injuries (four cases), moderately displaced with intralaryngeal defects (12 cases), and severe fractures with intralaryngeal avulsion injuries (four cases). Treatment consisted of either surgical reduction of fracture (and associated intralaryngeal injuries) or conservative, nonsurgical management. Results were graded subjectively as good, fair, or poor for airway and voice.
Chronic alcohol consumption alters periodontal health in rats.

BACKGROUND The aim of this study was to assess the effects of chronic alcohol consumption on periodontitis development in rats. METHODS Periodontal disease was experimentally induced by lipopolysaccharide (LPS; 2 mg/ml) injections into the gingival tissue around first upper and lower molar's neck, and into the interdental space between first and second molars. This protocol was repeated for 6 weeks on days 1, 3, and 5 of each week. Chronic alcohol consumption was induced by 20% ethanol (EtOH) as the only liquid source during 4 months. RESULTS Chronic alcohol consumption by itself increased alveolar bone loss and biological mediators of periodontal disease such as prostaglandin E2 (PGE2 ) content on gingival tissue, and inducible nitric oxide synthase activity plus PGE2 content in submandibular gland. Unexpectedly, alcohol consumption did not increase the damage evoked by the proved model of LPS injections for periodontitis induction. CONCLUSIONS Results suggest 20% alcohol consumption during 4 months generates differential effects on oral health of rats, depending on its pathophysiological state: It would exacerbate the inflammatory condition when periodontal damage is absent, but it would not when damage is installed.
Geographies of Politics, Geographies of Literature: Ezra Pound and Italian Modernism

Abstract Ezra Pound's commitment to Italian Fascism has been the subject of much critical debate. What has received less attention is the influence of Italian literary modernist culture(s) on his poetic project, in particular on the Cantos. This paper discusses Pound's response to Italy and Italian culture firstly by examining his engagement with the work of the Victorian poet Robert Browning. By showing the ways in which Pound viewed Browning's version of Italian history as limited in its scope, the paper demonstrates how the groundwork was laid for an interest in the more 'vigorous' literary cultures of Italian modernism, particularly those associated with Gabriele D'Annunzio and Filippo Tommasso Marinetti. D'Annunzio's and Marinetti's forging of a modern, nationalistic literature was, this paper suggests, an important step on the way towards Pound's whole-hearted adoption of Fascist politics. A detailed examination of Pound's poetry, political prose and correspondence shows how the American poet's engagement with these Italian figures can be seen to rest on the crossroads of aesthetic and political spheres.
Effect of systematic psychological preparation using visual illustration prior to gastrointestinal endoscopy on the anxiety of both pediatric patients and parents.

BACKGROUND Anxiety, a psychological response to stress, can affect a child undergoing medical procedures, and their family members. The purpose of the present study was to evaluate the benefit of detailed systematic information using a set of real photograph-based technical illustrations provided to both parents and patients before performing endoscopy on the level of anxiety. MATERIAL AND METHOD All children eligible for gastrointestinal endoscopy were consecutively enrolled from December 2003 to May 2004. Before and after providing systematic psychological preparation, the parents and patients older than five years of age were asked to score their anxiety on the procedures using visual analogue scale (VAS). RESULTS There were fifty-four patients enrolled during the study period Of these, twenty-five children were older than five years of age. The most common indication of gastrointestinal endoscopy was lower gastrointestinal bleeding. The esophagogastroduodenoscopy, colonoscopy, and both upper and lower endoscopies were performed in 50%, 37%, and 13% of the cases, respectively. The mean and standard deviation of VAS on anxiety of the parents (n = 54) before and after providing systematic information were 3.89 +/- 3.45 and 1.90 +/- 2.46, respectively (p < 0.001). These values on anxiety of the children older than 5 years of age before and after providing systematic information were 4.38 +/- 3.72 and 3.36 +/- 3.69, respectively (p = 0.143). There was no statistically significant impact of types ofp rocedure, level of education, family s income, age of children, and birth order on the level of anxiety. CONCLUSION The preparatory intervention using systematic visual illustration of the technical procedures in children undergoing gastrointestinal endoscopy could significantly reduce the parents' anxiety.
LINEAR PROGRAMMING APPLIED TO FINANCE - BUILDING A GREAT PORTFOLIO INVESTMENT

The stock market has grown steadily in recent years, and several indices have also been created in this market, like IGC, ISE and IBOVESPA. Thinking about this market growth, this paper aims to build an optimal portfolio using linear programming, based on companies simultaneously present in the indices: IGC and ISE. The constraints of the problem will be based on indicators of IBOVESPA. The model will be created to meet the restrictions set and to maximize the portfolio return, always comparing with the return of IBOVESPA, with a time horizon from 2007 until 2012. As results, the developed model was capable to provide better returns in fourteen of the twenty two periods under consideration. Besides, the average return considering all the periods was 0,03404 for the proposed model and -0,02086 for the IBOVESPA portfolio.
Multiproduct Duopoly with Vertical Differentiation

This paper investigates a two-stage competition in a vertically differentiated industry, where each firm produces an arbitrary number of similar qualities and sells them to heterogeneous consumers. The number of products, qualities, prices, and the extent of the market coverage are endogenously determined. We show that when unit costs of quality improvement are increasing and quadratic, each firm has an incentive to provide a disconnected set of similar qualities approximating a continuum. The finding contrasts sharply with the single-quality outcome when the market coverage is exogenously determined. We also show that allowing for multiple qualities intensifies the level of competition, lowers the profit of each firm, and raises the consumer surplus and the social welfare in comparison to the single-quality duopoly.
An Effective Approach to Evaluate the Training and Modeling Efficacy in MIMO Time-Varying Fading Channels

The efficacy of channel modeling and training for multiple-input multiple-output (MIMO) time-varying flat faded Rayleigh channels is studied herein from the information-theoretical perspective. To characterize the channel dynamics in wide-sense stationary uncorrelated scattering wireless environments, proper autoregressive (AR) channel models for different fading speeds are discussed from the viewpoints of the mean squared error (MSE) and Bayesian Cramér-Rao lower bound (BCRB) of channel estimation. Furthermore, the training efficacy is examined with the achievable capacity when the MSE of channel estimation attains the BCRB. Our numerical simulations show that neither is the first-order AR model enough, nor is a large-order AR model needed for modeling time-varying fading channels. The analysis on BCRB also shows that the influence of the multiple access interference among transmit antennas is not negligible for channel estimation in time-varying fading channels even if using orthogonal sequences for training. As channel tracking can utilize the current and all past training symbols, the optimal training lengths for each data packet may be less than the number of transmit antennas. These results help re-examine the efficacy of model complexity and training overhead, and characterize the achievable rate for MIMO systems that use more practical methods in estimating Rayleigh fading channels.
The bent-end morphology of Treponema phagedenis is associated with short, left-handed, periplasmic flagella

Treponema phagedenis Kazan 5 is a spirochete with multiple periplasmic flagella attached near each end of the cell cylinder. Dark-field microscopy revealed that most of the cell is right-handed (helix diameter, 0.23 micron; helix pitch, 1.74 microns), and the ends appear bent. These ends could move and gyrate while the central part of the cell remained stationary. The present study examines the basis for the bent-end characteristic. Motility mutants deficient in periplasmic flagella were found to lack the bent ends, and spontaneous revertants to motility regained the periplasmic flagella and bent-end characteristic. The length of the bent ends (2.40 microns) was found to be similar to the length of the periplasmic flagella as determined by electron microscopy (2.50 microns). The helix diameter of the bent ends was 0.57 micron, and the helix pitch of the bent ends was 1.85 microns. The periplasmic flagella were short relative to the length of the cells (15 microns) and, in contrast to the reports of others, did not overlap in the center of the cell. Similar results were found with T. phagedenis Reiter. The results taken together indicate that there is a causal relationship between the bent-end morphology and the presence of short periplasmic flagella. We report the first three-dimensional description of spirochete periplasmic flagella. Dark-field microscopy of purified periplasmic flagella revealed that these organelles were left-handed (helix diameter, 0.36 microns; helix pitch, 1.26 microns) and only 1 to 2 wavelengths long. Because of a right-handed cell cylinder and left-handed periplasmic flagella along with bent ends having helix diameters greater than those of either the cell cylinder or periplasmic flagella, we conclude that there is a complex interaction of the periplasmic flagella and the cell cylinder to form the bent ends. The results are discussed with respect to a possible mechanism of T. phagedenis motility.
Spatio-Temporal Feature-Extraction Techniques for Isolated Gesture Recognition in Arabic Sign Language

This paper presents various spatio-temporal feature-extraction techniques with applications to online and offline recognitions of isolated Arabic Sign Language gestures. The temporal features of a video-based gesture are extracted through forward, backward, and bidirectional predictions. The prediction errors are thresholded and accumulated into one image that represents the motion of the sequence. The motion representation is then followed by spatial-domain feature extractions. As such, the temporal dependencies are eliminated and the whole video sequence is represented by a few coefficients. The linear separability of the extracted features is assessed, and its suitability for both parametric and nonparametric classification techniques is elaborated upon. The proposed feature-extraction scheme was complemented by simple classification techniques, namely, K nearest neighbor (KNN) and Bayesian, i.e., likelihood ratio, classifiers. Experimental results showed classification performance ranging from 97% to 100% recognition rates. To validate our proposed technique, we have conducted a series of experiments using the classical way of classifying data with temporal dependencies, namely, hidden Markov models (HMMs). Experimental results revealed that the proposed feature-extraction scheme combined with simple KNN or Bayesian classification yields comparable results to the classical HMM-based scheme. Moreover, since the proposed scheme compresses the motion information of an image sequence into a single image, it allows for using simple classification techniques where the temporal dimension is eliminated. This is actually advantageous for both computational and storage requirements of the classifier
Research and Policy: Can Online Learning Communities Foster Professional Development?

This column posits enhancing professional development through uses of digital tools to create professional learning communities (PLCs) designed to support collective inquiry and action research leading to schoolwide improvement. These digital tools include a social networking/discussion forum for teacher collaboration; teachers’ individual personal learning networks (PLNs); students' online work collected in blogs, wikis, podcasts, or e-portfolios; and a school online curriculum repository containing lesson plans and units addressing standards that are linked together to create a central “learning commons. ”— Implementing this “learning commons” requires initial pilot testing of the uses of these tools prior to full-scale implementation. Research supporting the use of digital tools for enhancing professional development is also cited.
Dialysate calcium concentration and the risk of sudden cardiac arrest in hemodialysis patients.

BACKGROUND AND OBJECTIVES The optimal dialysate calcium concentration to maintain normal mineralization and reduce risk of cardiovascular events in hemodialysis patients is debated. Guidelines suggest that dialysate Ca concentration should be lowered to avoid vascular calcification, but cardiac arrhythmias may be more likely to occur at lower dialysate Ca. Concurrent use of QT-prolonging medications may also exacerbate arrhythmic risk. This study examined the influence of serum Ca, dialysate Ca, and QT interval-prolonging medications on the risk of sudden cardiac arrest in a cohort of hemodialysis patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This case-control study among 43,200 hemodialysis patients occurred between 2002 and 2005; 510 patients who experienced a witnessed sudden cardiac arrest were compared with 1560 matched controls. This study examined covariate-adjusted sudden cardiac arrest risk associations with serum Ca, dialysate Ca, serum dialysate Ca gradient, and prescription of QT-prolonging medications using logistic regression techniques. RESULTS Patients assigned to low Ca dialysate<2.5 mEq/L were more likely to be exposed to larger serum dialysate Ca gradient and had a greater fall in BP during dialysis treatment. After accounting for covariates and baseline differences, low Ca dialysate<2.5 mEq/L (odds ratio=2.00, 95% confidence interval=1.40-2.90), higher corrected serum Ca (odds ratio=1.10, 95% confidence interval=1.00-1.30), and increasing serum dialysate Ca gradient (odds ratio=1.40, 95% confidence interval=1.10-1.80) were associated with increased risk of sudden cardiac arrest, whereas there were no significant risk associations with QT-prolonging medications. CONCLUSIONS Increased risk of sudden cardiac arrest associated with low Ca dialysate and large serum dialysate Ca gradients should be considered in determining the optimal dialysate Ca prescription.
Dural Ectasia in Marfan Syndrome: A Case Control Study

BACKGROUND AND PURPOSE: Dural ectasia (DE) is one of the major criteria of Marfan syndrome (MFS). Our aim was to establish the prevalence of DE in an adult population fulfilling the Ghent criteria for MFS and to assess definitions of DE. MATERIALS AND METHODS: One hundred five adults with suspected MFS were included. MR imaging at 1.5T was performed unless contraindicated; then CT was obtained. Lumbosacral anteroposterior vertebral body diameters (VBD) and dural sac diameters (DSD) were measured. Dural sac ratios (DSR = DSD/VBD) at levels L3 through S1 were calculated. Anterior meningoceles, herniations of nerve root sleeves, and scalloping were characterized. One hundred one sex- and age-matched patients were included as controls. RESULTS: We identified 3 patient groups: 1) fulfilling Ghent criteria independent of DE (n = 73), 2); fulfilling Ghent criteria dependent on DE (n = 14), and 3); and suspected MFS, not fulfilling Ghent criteria (n = 18). DE was found in 86% of group 1. At levels L4-S1, mean DSRs were significantly higher in group 1 than in group 3 and controls (P < .001). Herniations of the nerve root sleeves were present in 73% in group 1 versus 1% in controls. Anterior meningoceles were found in 37% and 14% in groups 1 and 2, respectively, but not in group 3 or controls. CONCLUSIONS: The diagnosis of DE on MR imaging or CT should be based on the presence of at least 1 of the following criteria: anterior meningoceles or nerve root sleeve herniation, DSD at S1 or below larger than DSD at L4, and DSR at S1 >0.59.
Efficient rescue of infectious bursal disease virus from cloned cDNA: evidence for involvement of the 3'-terminal sequence in genome replication.

To study the mechanism of replication of infectious bursal disease virus (IBDV), and to determine factors on the IBDV RNA which are involved in viral replication, we used cloned full-length cDNA of both the A- and B-segments to generate infectious IBDV. Infectious IBDV was rescued from plasmids that contained full-length IBDV cDNA behind a T7 promoter, by transfecting these plasmids into cells which were infected with a recombinant Fowlpox virus that expressed T7 RNA polymerase. By using the cDNA transfection system we evaluated the effect of the length of the 3' terminus of the A-segment plus strand of IBDV. Although wild-type IBDV predominantly contains four cytosines at the 3' terminus, no difference in virus yield was found when virus was rescued from cDNAs containing three to six adjacent cytosines. When the 3' terminus was shorter than three cytosines the efficiency to generate infectious IBDV from cDNA was reduced, but IBDV could still be recovered reproducibly. The rescued viruses from cDNAs containing 3'-terminal deletions appeared to have a restored 3'-terminal sequence. The missing nucleotides are probably restored by using complementary bases of a stem-loop structure as template.
In vitro effects of penicillin and telithromycin on the expression of Streptococcus pneumoniae capsule.

OBJECTIVE To evaluate the effects of subinhibitory concentrations of penicillin and telithromycin on capsular formation by Streptococcus pneumoniae. METHODS A total of 60 isolates of S. pneumoniae, 20 susceptible, 20 intermediately resistant and 20 resistant to penicillin, were studied. All isolates were susceptible to telithromycin. RESULTS All isolates were capsulate when grown without antibiotics. Encapsulation was lower after incubation with telithromycin as compared with penicillin in isolates susceptible to penicillin (20% versus 75%), in those intermediately resistant to penicillin (25% versus 95%) and in isolates fully resistant to penicillin (15% versus 100%) (P < 0.01). CONCLUSIONS Telithromycin appears to be superior to penicillin in reducing the expression of the capsule by S. pneumoniae.
Process Options Impact on ESD Diode Performance in Bulk FinFET Technology

Bulk FinFET is the main technology option for sub-20-nm CMOS nodes. However, newly introduced process options in advanced bulk FinFET technologies can result in significant deterioration of intrinsic electrostatic discharge (ESD) performance. In this paper, the impact on ESD performance induced by the process options beyond 20-nm nodes is explored on the ESD protection diodes.