Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementing Creating Lasting Family Connections with reentry fathers: A partial replication during a period of policy change

ABSTRACT The present study is a replication of the Creating Lasting Family Connections Fatherhood Program (CLFCFP) using a randomized controlled trial (RCT). CLFCFP has been shown in prior studies to have a positive impact on relationship skills and recidivism using weaker quasi-experimental designs (McKiernan et al., 2013). Survey data on relationship skills and recidivism data came from 280 men in prison reentry. Findings for relationship skills were replicated in this RCT, suggesting CLFCFP participants had larger sustained improvements in relationship skills. Policy changes occurring shortly before the study possibly serve as an explanation for our inability to replicate recidivism findings.
Why Trump and Clinton won and lost: the roles of hypermasculinity and androgyny

Purpose The purpose of this study is to examine perceptions of the “Ideal President” (IP) and presidential candidates in the 2016 U.S. presidential election in relation to gender stereotypes and leader prototypes. Design/methodology/approach Three hundred seventy-eight business students assessed perceptions of either the IP or a particular candidate on measures of masculinity and femininity. Androgyny (balance of masculinity and femininity) and hypermasculinity (extremely high masculinity) scores were calculated from these measures. Findings The IP was perceived as higher in masculinity than femininity, but less similar to the male (Donald Trump) than the female (Hillary Clinton) candidate. IP perceptions were more androgynous than in the 2008 U.S. presidential election. Respondents’ political preferences were related to their IP perceptions on hypermasculinity, which in turn were consistent with perceptions of their preferred candidate. Originality/value The study extends the literature on the linkages b.
Variations of Soil Microbial Community Structures Beneath Broadleaved Forest Trees in Temperate and Subtropical Climate Zones

Global warming has shifted climate zones poleward or upward. However, understanding the responses and mechanism of microbial community structure and functions relevant to natural climate zone succession is challenged by the high complexity of microbial communities. Here, we examined soil microbial community in three broadleaved forests located in the Wulu Mountain (WLM, temperate climate), Funiu Mountain (FNM, at the border of temperate and subtropical climate zones), or Shennongjia Mountain (SNJ, subtropical climate). Although plant species richness decreased with latitudes, the microbial taxonomic α-diversity increased with latitudes, concomitant with increases in soil total and available nitrogen and phosphorus contents. Phylogenetic NRI (Net Relatedness Index) values increased from -0.718 in temperate zone (WLM) to 1.042 in subtropical zone (SNJ), showing a shift from over dispersion to clustering likely caused by environmental filtering such as low pH and nutrients. Similarly, taxonomy-based association networks of subtropical forest samples were larger and tighter, suggesting clustering. In contrast, functional α-diversity was similar among three forests, but functional gene networks of the FNM forest significantly (P < 0.050) differed from the others. A significant correlation (R = 0.616, P < 0.001) between taxonomic and functional β-diversity was observed only in the FNM forest, suggesting low functional redundancy at the border of climate zones. Using a strategy of space-for-time substitution, we predict that poleward climate range shift will lead to decreased microbial taxonomic α-diversities in broadleaved forest.
The Fallacy of Crowding-Out: A Note on "Native Internal Migration and the Labor Market Impact of Immigration"

In â€œNative Internal Migration and the Labor Market Impact of Immigration,â€ George Borjas (2006) identifies a strong negative correlation between immigration and native-born employment in the US using local area data. This relationship is particularly strong at the metropolitan area level, weaker but still significant at the state level, and weakest at the Census region level. In this note, we show that Borjasâ€™s negative correlation arises due to the construction of the dependent and explanatory variables rather than from any true negative association between the employment growth of immigrants and natives. Borjas regresses log native employment, ln(Nt), on the share of foreign-born employment, pt = Mt/(Mt + Nt), across skill-state-year cells. The specification therefore includes native employment in the numerator of the dependent variable and in the denominator of the explanatory variable. This builds a negative correlation into the model that is particularly strong if the variance of Nt relative to Mt is large. To illustrate, we first show that state and city level regressions of the standardized native employment change, (Nt+10âˆ’Nt)/(Mt+Nt), on standardized immigration, (Mt+10 âˆ’Mt)/(Mt+Nt), always find a positive and mostly significant correlation between the two. Second, we randomly simulate changes in the native and foreign-born workforce with a data generating process that has zero or positive correlation between the shocks I”Mt and I”Nt (i.e., so that immigration is associated with either no change or an increase in native employment). Borjas specifications employing this simulated data estimate large and significantly negative coefficients as long as the variance of I”Nt is larger than the variance of I”Mt, which is true in observed state-level and city-level data.
Activity of the beta 3 nicotinic receptor promoter is a marker of neuron fate determination during retina development

We have previously shown that transcription of the beta 3 nicotinic receptor gene within the chick CNS is regulated by a promoter 143 base pairs (bp) in length. Here, we demonstrate that in the developing visual system this promoter is active in a subset of retinal cells, the majority of which are ganglion cells. Because the beta 3 promoter is activated very early during retina development, it can provide a marker of ganglion cell induction and differentiation. Transfection of neuroretina explants enabled us to detect activity of the beta 3 promoter in premigratory cells localized on the ventricular side of the retina. Double-labeling experiments showed that activation of the beta 3 promoter takes place before the last S-phase, suggesting that this particular phenotypic trait is determined when precursor cells are still proliferating. The beta 3 phenotype is induced in about one-tenth of the total pool of retinal progenitor cells and is stable upon changing the cellular environment. Our study suggests that at the very early stages of retina neurogenesis, some lineage restrictions have already occurred in the population of retinal progenitor cells.
On the Anonymization of Sparse High-Dimensional Data

Existing research on privacy-preserving data publishing focuses on relational data: in this context, the objective is to enforce privacy-preserving paradigms, such as k- anonymity and lscr-diversity, while minimizing the information loss incurred in the anonymizing process (i.e. maximize data utility). However, existing techniques adopt an indexing- or clustering- based approach, and work well for fixed-schema data, with low dimensionality. Nevertheless, certain applications require privacy-preserving publishing of transaction data (or basket data), which involves hundreds or even thousands of dimensions, rendering existing methods unusable. We propose a novel anonymization method for sparse high-dimensional data. We employ a particular representation that captures the correlation in the underlying data, and facilitates the formation of anonymized groups with low information loss. We propose an efficient anonymization algorithm based on this representation. We show experimentally, using real-life datasets, that our method clearly outperforms existing state-of-the-art in terms of both data utility and computational overhead.
Multigrid solution of the Eu-ler equations for aircraft configurations

A multigrid scheme for solving the Euler equations is presented. The method has been successfully applied to two-dimensional airfoil calculations on both O-type and C-type meshes. In three dimensions the scheme has proved equally effective and calclations of flows over wing/body combinations are possible with convergence achieved in less than 100 cycles.
INVESTIGATING MOTHERS ’ EMPATHIC INCLINATION AND MIND READING LEVELS FROM EYES WHO HAVE CHILDREN WITH AUTISM AND TYPICALLY DEVELOPING CHILDREN

The purpose of this study was to investigate empathic inclination and mind reading levels from eyes of mothers‟ who have children with autism (N=26) and typically developing children (N=28). It was a descriptive study which examines comparatively mind reading skills of mothers of children with autism and mothers of typically developed children. In order to assess mind reading skills of mothers “Eyes Test” was used. Also “Empathic Tendency Scale” was used for assessing empathic tendencies and skills of the mothers. According to results, mothers who have normally developed children performed better at mind reading from eyes, than mothers who have children with autism. On the other hand, there was no significant difference between two groups in empathic inclination results. This study has similar results with prior studies.
Cornea in Helminth-Mediated Keratitis Essential for Neutrophil Recruitment to the Chemokine Receptor 1 Expression Is CXC Chemokine Receptor 2 But Not C-C

Inﬁltration of neutrophils and eosinophils into the mammalian cornea can result in loss of corneal clarity and severe visual impairment. To identify mediators of granulocyte recruitment to the corneal stroma, we determined the relative contribution of chemokine receptors CXC chemokine receptor (CXCR)-2 (IL-8R homologue) and CCR1 using a murine model of ocular onchocerciasis (river blindness) in which neutrophils and eosinophils migrate from peripheral vessels to the central cornea. CXCR2 2 / 2 and CCR1 2 / 2 mice were immunized s.c. and injected into the corneal stroma with Ags from the parasitic helminth Onchocerca volvulus . We found that production of macrophage-inﬂammatory protein (MIP)-2, KC, and MIP-1 a was localized to the corneal stroma, rather than to the epithelium, which was consistent with the location of neutrophils in the cornea. CCR1 deﬁciency did not inhibit neutrophil or eosinophil inﬁltration to the cornea or development of corneal opaciﬁcation. In marked contrast, neutrophil recruitment to the corneas of CXCR2 2 / 2 mice was signiﬁcantly impaired ( p < 0.0001 compared with control, BALB/c mice) with only occasional neutrophils detected in the central cornea. Furthermore, CXCR2 2 / 2 mice developed only mild corneal opaciﬁcation compared with BALB/c mice. These differences were not due to impaired KC and MIP-2 production in the corneal stroma of CXCR2 2 / 2 mice, which was similar to BALB/c mice. Furthermore, although MIP-1 a production was lower in CXCR2 2 / 2 mice than BALB/c mice, eosinophil recruitment to the cornea was not impaired. These observations demonstrate the critical role for CXCR2 expression in neutrophil inﬁltration to the cornea and may indicate a target for immune intervention in neutrophil-mediated corneal inﬂammation. The Journal of Immunology, 2001, 166: 4035–4041.
In Vitro Evaluation of Antiprotozoal and Antiviral Activities of Extracts from Argentinean Mikania Species

The aim of this study was to investigate the antiprotozoal and antiviral activities of four Argentinean Mikania species. The organic and aqueous extracts of Mikania micrantha, M. parodii, M. periplocifolia, and M. cordifolia were tested on Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes, and dengue virus type 2. The organic extract of M. micrantha was the most active against T. cruzi and L. braziliensis exhibiting a growth inhibition of 77.6 ± 4.5% and 84.9 ± 6.1%, respectively, at a concentration of 10 μg/ml. The bioguided fractionation of M. micrantha organic extract led to the identification of two active fractions. The chromatographic profile and infrared analysis of these fractions revealed the presence of sesquiterpene lactones. None of the tested extracts were active against dengue virus type 2.
Development of ST-246® for Treatment of Poxvirus Infections

ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced cytopathic effects. The antiviral activity is specific for orthopoxviruses and the compound does not inhibit the replication of other RNA- and DNA-containing viruses or inhibit cell proliferation at concentrations of compound that are antiviral. ST-246 targets vaccinia virus p37, a viral protein required for envelopment and secretion of extracellular forms of virus. The compound is orally bioavailable and protects multiple animal species from lethal orthopoxvirus challenge. Preclinical safety pharmacology studies in mice and non-human primates indicate that ST-246 is readily absorbed by the oral route and well tolerated with the no observable adverse effect level (NOAEL) in mice measured at 2000 mg/kg and the no observable effect level (NOEL) in non-human primates measured at 300 mg/kg. Drug substance and drug product processes have been developed and commercial scale batches have been produced using Good Manufacturing Processes (GMP). Human phase I clinical trials have shown that ST-246 is safe and well tolerated in healthy human volunteers. Based on the results of the clinical evaluation, once a day dosing should provide plasma drug exposure in the range predicted to be antiviral based on data from efficacy studies in animal models of orthopoxvirus disease. These data support the use of ST-246 as a therapeutic to treat pathogenic orthopoxvirus infections of humans.
Brand (In)fidelity: when flirting with the competition strengthens brand relationships

We document the existence and consequences of brand flirting: a short-lived experience in which a consumer engages with and/or indulges in the alluring qualities of a brand without committing to it. We propose that brand flirting is exciting, and that when consumers flirt with a brand other than their typically preferred brand in the same product category, they can transfer this excitement to their preferred brand—resulting in even greater love and desire for it. Consistent with this conceptual account, we demonstrate that this brand flirting effect is mediated by excitement. Moreover, the brand flirting effect is most likely to emerge under conditions that facilitate arousal transfer: when consumers are highly committed to their preferred brand, and when the brand with which consumers flirt is similar to their preferred brand.
Component-specific, cigarette particle deposition modeling in the human respiratory tract

Abstract Inhalation of cigarette smoke particles (CSP) leads to adverse health effects in smokers. Determination of the localized dose to the lung of the inhaled smoke aids in determining vulnerable sites, and identifying components of the smoke that may be responsible for the adverse effects; thus providing a roadmap for harm reduction of cigarette smoking. A particle deposition model specific to CSP was developed for the oral cavity and the lung by accounting for cigarette particle size growth by hygroscopicity, phase change and coagulation. In addition, since the cigarette puff enters the respiratory tract as a dense cloud, the cloud effect on particle drag and deposition was accounted for in the deposition model. Models of particle losses in the oral cavities were developed during puff drawing and subsequent mouth-hold. Cigarette particles were found to grow by hygroscopicity and coagulation, but to shrink as a result of nicotine evaporation. The particle size reached a plateau beyond which any disturbances in the environmental conditions caused the various mechanisms to balance each other out and the particle size remain stable. Predicted particle deposition considering the cloud effects was greater than when treated as a collection of non-interacting particles (i.e. no cloud effects). Accounting for cloud movement provided the necessary physical mechanism to explain the greater than expected, experimentally observed and particle deposition. The deposition model for CSP can provide the necessary input to determine the fate of inhaled CSP in the lung. The knowledge of deposition will be helpful for health assessment and identification and reduction of harmful components of CSP.
Improving social bookmark search using personalised latent variable language models

Social tagging systems have recently become very popular as a method of categorising information online and have been used to annotate a wide range of different resources. In such systems users are free to choose whatever keywords or "tags" they wish to annotate each resource, resulting in a highly personalised, unrestricted vocabulary. While this freedom of choice has several notable advantages, it does come at the cost of making searching of these systems more difficult as the vocabulary problem introduced is more pronounced than in a normal information retrieval setting. In this paper we propose to use hidden topic models as a principled way of reducing the dimensionality of this data to provide more accurate resource rankings with higher recall. We first describe Latent Dirichlet Allocation (LDA), a simple topic model and then introduce 2 extended models which can be used to personalise the results by including information about the user who made each annotation. We test these 3 models and compare them with 3 non-topic model baselines on a large data sample obtained from the Delicious social bookmarking site. Our evaluations show that our methods significantly outperform all of the baselines with the personalised models also improving significantly upon unpersonalised LDA.
Selection of Suitable Reference Genes for RT-qPCR Normalization under Abiotic Stresses and Hormone Stimulation in Persimmon (Diospyros kaki Thunb)

The success of quantitative real-time reverse transcription polymerase chain reaction (RT-qPCR) to quantify gene expression depends on the stability of the reference genes used for data normalization. To date, systematic screening for reference genes in persimmon (Diospyros kaki Thunb) has never been reported. In this study, 13 candidate reference genes were cloned from 'Nantongxiaofangshi' using information available in the transcriptome database. Their expression stability was assessed by geNorm and NormFinder algorithms under abiotic stress and hormone stimulation. Our results showed that the most suitable reference genes across all samples were UBC and GAPDH, and not the commonly used persimmon reference gene ACT. In addition, UBC combined with RPII or TUA were found to be appropriate for the "abiotic stress" group and α-TUB combined with PP2A were found to be appropriate for the "hormone stimuli" group. For further validation, the transcript level of the DkDREB2C homologue under heat stress was studied with the selected genes (CYP, GAPDH, TUA, UBC, α-TUB, and EF1-α). The results suggested that it is necessary to choose appropriate reference genes according to the test materials or experimental conditions. Our study will be useful for future studies on gene expression in persimmon.
Functional Fields in Human Auditory Cortex Revealed by Time-Resolved fMRI without Interference of EPI Noise

The gradient switching during fast echoplanar functional magnetic resonance imaging (EPI-fMRI) produces loud noises that may interact with the functional activation of the central auditory system induced by experimental acoustic stimuli. This interaction is unpredictable and is likely to confound the interpretation of functional maps of the auditory cortex. In the present study we used an experimental design which does not require the presentation of stimuli during EPI acquisitions and allows for mapping of the auditory cortex without the interference of scanner noise. The design relies on the physiological delays between the onset, or the end, of stimulation and the corresponding hemodynamic response. Owing to these delays and through a time-resolved acquisition protocol it is possible to analyze the decay of the stimulus-specific signal changes after the cessation of the stimulus itself and before the onset of the EPI-acoustic noise related activation (decay-sampling technique). This experimental design, which might permit a more detailed insight in the auditory cortex, has been applied to the study of the cortical responses to pulsed 1000 Hz sine tones. Distinct activation clusters were detected in the Heschl's gyri and the planum temporale, with an increased extension compared to a conventional block-design paradigm. Furthermore, the comparison of the hemodynamic response of the most anterior and the posterior clusters of activation highlighted differential response patterns to the sound stimulation and to the EPI-noise. These differences, attributable to reciprocal saturation effects unevenly distributed over the superior temporal cortex, provided evidence for functionally distinct auditory fields.
CORRELATION BETWEEN SELF-EFFICACY AND SELF-ESTEEM IN STUDENTS

McKenzie Jill K. The purpose of this study was to determine the correlation between self-efficacy and self-esteem in students. Historical framework was based on Alfed Bandura and Mark Sherer's research. Data was collected on the research areas of self-efficacy and self-esteem theories and the role of education on self-efficacy and self-esteem and education's affect on students. Data analysis was constructed by use of the Pearson r coefficient and t-tests. The research data collected found that the only statistically significant difference was found on self-esteem and gender, with males having a significantly higher overall score on self-esteem than females. Further study is recommended to determine effects of self-esteem enhancement programs for females.
Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization.

AIMS Erythropoietin (EPO) improves cardiac function and induces neovascularization in chronic heart failure (CHF), although the exact mechanism has not been elucidated. We studied the effects of EPO on homing and incorporation of endothelial progenitor cells (EPC) into the myocardial microvasculature and myocardial expression of angiogenic factors. METHODS AND RESULTS CHF was induced in rats by coronary artery ligation resulting in myocardial infarction (MI) after bone marrow had been replaced by human placental alkaline phosphatase (hPAP) transgenic cells. We studied the effects of darbepoetin alfa treatment (EPO, 40 microg/kg, every 3 weeks, starting 3 weeks after MI) on longitudinal changes in left ventricular (LV) function, circulating EPC, myocardial histology, and expression of vascular endothelial growth factor (VEGF) determined 9 weeks after MI. EPO prevented LV-dilatation and improved cardiac function (all P < 0.05), which was associated with 42% increased capillary growth (P < 0.01). EPO-induced mobilization of EPC from the bone marrow (P < 0.01), which resulted in a three-fold increased homing of EPC into the cardiac microvasculature. The percentage of the endothelium that consisted of bone marrow derived cells was significantly increased (3.9 +/- 0.5 vs. 11.4 +/- 1%, P < 0.001) comprising 30% of the newly formed capillaries. In addition, EPO treatment resulted in a 4.5-fold increased myocardial expression of VEGF, which correlated strongly with neovascularization (r = 0.67; P < 0.001). VEGF was equally expressed by endothelial cells of myocardial and bone marrow origin. CONCLUSION EPO-induced neovascularization in post-MI heart failure is mediated through a combination of EPC recruitment from the bone marrow and increased myocardial expression of VEGF.