Miracle-dz/UniFAR-FTUs huggingface dataset:
The psychological contract : personal and job–related variables and the intention to leave

The primary purpose of this research was to determine the relationship between job characteristics (the type of contract, gender, age, tenure) and the psychological contract (employer‘s obligation and employee‘s obligations), autonomy, employability, job satisfaction, life satisfaction and the intention to leave. A cross-sectional survey design was conducted among 297 security employees in a private company situated in Vanderbijlpark. A total number of 217 respondents completed the questionnaire, which is a response rate of 73%. No significant relationship was found between years of tenure and employability. A practically significant relationship with a large effect exists between employer obligations and job satisfaction, whereas a practical significant relationship with a medium effect was established between employee obligations and job satisfaction. If an employee shows job satisfaction, he/she is less likely to leave the employer.
Memory, Interference and Depression.

Is forgetting in the short-term due to decay with the mere passage of time, interference from other memoranda, or both? Past research on short-term memory (STM) has revealed some evidence for decay and a plethora of evidence showing that STM is worsened by interference. However, none of these studies has directly contrasted decay and interference in STM in a task that rules out the use of rehearsal processes. In this paper we present a series of studies using a novel paradigm to address this problem directly, by interrogating the operation of decay and interference in STM without rehearsal confounds. The results of these studies indicate that short-term memories are subject to very small decay effects with the mere passage of time, but that interference plays a much larger role in their degradation. We discuss the implications of these results for existing models of memory decay and interference.
Anti‐inflammatory drugs, analgesics and the risk of perforated colonic diverticular disease

Acute perforated colonic diverticular disease has a mortality rate of up to 30 per cent, but little is known about its aetiology. The aim of this study was to test the hypothesis that three classes of drugs, namely non‐steroidal anti‐inflammatory drugs (NSAIDs), opioid analgesics and corticosteroids, are risk factors for perforated diverticular disease.
Ab-Initio Investigations of Magnetic Properties and Induced Half-Metallicity in Ga1−xMnxP (x = 0.03, 0.25, 0.5, and 0.75) Alloys

Ab-initio calculations are performed to examine the electronic structures and magnetic properties of spin-polarized Ga1−xMnxP (x = 0.03, 0.25, 0.5, and 0.75) ternary alloys. In order to perceive viable half-metallic (HM) states and unprecedented diluted magnetic semiconductors (DMSs) such as spintronic materials, the full potential linearized augmented plane wave method is utilized within the generalized gradient approximation (GGA). In order to tackle the correlation effects on 3d states of Mn atoms, we also employ the Hubbard U (GGA + U) technique to compute the magnetic properties of an Mn-doped GaP compound. We discuss the emerged global magnetic moments and the robustness of half-metallicity by varying the Mn composition in the GaP compound. Using GGA + U, the results of the density of states demonstrate that the incorporation of Mn develops a half-metallic state in the GaP compound with an engendered band gap at the Fermi level (EF) in the spin–down state. Accordingly, the half-metallic feature is produced through the hybridization of Mn-d and P-p orbitals. However, the half-metallic character is present at a low x composition with the GGA procedure. The produced magnetic state occurs in these materials, which is a consequence of the exchange interactions between the Mn-element and the host GaP system. For the considered alloys, we estimated the X-ray absorption spectra at the K edge of Mn. A thorough clarification of the pre-edge peaks is provided via the results of the theoretical absorption spectra. It is inferred that the valence state of Mn in Ga1−xMnxP alloys is +3. The predicted theoretical determinations surmise that the Mn-incorporated GaP semiconductor could inevitably be employed in spintronic devices.
Carotene Hydroxylase Activity Determines the Levels of Both α-Carotene and Total Carotenoids in Orange Carrots[W]

High α-carotene levels present in orange carrots correlate with an insertion in the cytochrome P450 carotene hydroxylase gene CYP97A3/lut5. Overexpression of Arabidopsis lut5 in orange carrots reduces α-carotene and total carotenoid levels as well as the levels of phytoene synthase. This suggests feedback regulation by xanthophyll-derived metabolites acting at levels beyond transcription. The typically intense carotenoid accumulation in cultivated orange-rooted carrots (Daucus carota) is determined by a high protein abundance of the rate-limiting enzyme for carotenoid biosynthesis, phytoene synthase (PSY), as compared with white-rooted cultivars. However, in contrast to other carotenoid accumulating systems, orange carrots are characterized by unusually high levels of α-carotene in addition to β-carotene. We found similarly increased α-carotene levels in leaves of orange carrots compared with white-rooted cultivars. This has also been observed in the Arabidopsis thaliana lut5 mutant carrying a defective carotene hydroxylase CYP97A3 gene. In fact, overexpression of CYP97A3 in orange carrots restored leaf carotenoid patterns almost to those found in white-rooted cultivars and strongly reduced α-carotene levels in the roots. Unexpectedly, this was accompanied by a 30 to 50% reduction in total root carotenoids and correlated with reduced PSY protein levels while PSY expression was unchanged. This suggests a negative feedback emerging from carotenoid metabolites determining PSY protein levels and, thus, total carotenoid flux. Furthermore, we identified a deficient CYP97A3 allele containing a frame-shift insertion in orange carrots. Association mapping analysis using a large carrot population revealed a significant association of this polymorphism with both α-carotene content and the α-/β-carotene ratio and explained a large proportion of the observed variation in carrots.
The impact of entitled and humble attitudes on romantic satisfaction

Entitlement, the sense of deserving more than others, has been shown to be associated with several negative interpersonal outcomes. In this dissertation, the impact of entitlement on romantic relationship satisfaction was investigated. On the other hand, psychological literature suggests humility may benefit interpersonal relationships. The impact of humility on relationship satisfaction was also examined in this dissertation. A sample of 158 individuals in monogamous romantic relationships of at least one year completed self-report measures of trait entitlement, relational entitlement, humility, relationship satisfaction, positive affect maintenance skills, and negative affect reduction skills. As expected, trait entitlement and relational entitlement were both significant negative predictors of relationship satisfaction. Also as expected, humility was a significant positive predictor of relational satisfaction. Additionally, results showed trait entitlement significantly moderated the relationship between negative affect reduction and relational satisfaction, such that participants with low levels of trait entitlement showed a stronger relationship between negative affect reduction and relationship satisfaction than participants who scored high on entitlement. Degree Type Dissertation Rights Terms of use for work posted in CommonKnowledge. Comments Library Use: LIH This dissertation is available at CommonKnowledge: http://commons.pacificu.edu/spp/1096 Copyright and terms of use If you have downloaded this document directly from the web or from CommonKnowledge, see the “Rights” section on the previous page for the terms of use. If you have received this document through an interlibrary loan/document delivery service, the following terms of use apply: Copyright in this work is held by the author(s). You may download or print any portion of this document for personal use only, or for any use that is allowed by fair use (Title 17, §107 U.S.C.). Except for personal or fair use, you or your borrowing library may not reproduce, remix, republish, post, transmit, or distribute this document, or any portion thereof, without the permission of the copyright owner. [Note: If this document is licensed under a Creative Commons license (see “Rights” on the previous page) which allows broader usage rights, your use is governed by the terms of that license. ] Inquiries regarding further use of these materials should be addressed to: CommonKnowledge Rights, Pacific University Library, 2043 College Way, Forest Grove, OR 97116, (503) 352-7209. Email inquiries may be directed to:. copyright@pacificu.edu This dissertation is available at CommonKnowledge: http://commons.pacificu.edu/spp/1096 THE IMPACT OF ENTITLED AND HUMBLE ATTITUDES ON ROMANTIC SATISFACTION A DISSERTATION SUBMITTED TO THE FACULTY OF SCHOOL OF PROFESSIONAL PSYCHOLOGY PACIFIC UNIVERSITY HILLSBORO, OREGON BY CAMILLE C. CURRY IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PSYCHOLOGY
Cyclic RGD peptide-modified liposomal drug delivery system: enhanced cellular uptake in vitro and improved pharmacokinetics in rats

Background Integrins αvβ3 and αvβ5, both of which specifically recognize the Arg-Gly-Asp (RGD) motif, are overexpressed on many solid tumors and in tumor neovasculature. Thus, coupling the RGD motif to the liposomal surface for achieving active targeting can be a promising strategy for the treatment of tumors. Methods Cyclo(Arg-Gly-Asp-D-Phe-Cys) (cRGD) was covalently coupled with the liposomal membrane surface, followed by coating with poly(ethylene glycol) (PEG) using the post-insertion technique. The coupling efficiency of cRGD was determined. Doxorubicin as a model anticancer drug was loaded into liposomes using an ammonium sulfate gradient method to investigate the encapsulation efficiency, cellular uptake by the integrin-overexpressing human glioma cell line U87MG in vitro, and pharmacokinetic properties in Sprague-Dawley rats. Results cRGD was conjugated to the liposomal surface by a thiol-maleimide coupling reaction. The coupling efficiency reached 98%. The encapsulation efficiency of doxorubicin in liposomes was more than 98%. The flow cytometry test result showed that cRGD-modified liposomes (RGD-DXRL-PEG) had higher cell uptake by U87MG cells, compared with nontargeted liposomes (DXRL-PEG). The cellular uptake was significantly inhibited in the presence of excess free cRGD. Both the targeted (t1/2 = 24.10 hours) and non-targeted (t1/2 = 25.32 hours) liposomes showed long circulating properties in rat plasma. The area under the curve of the targeted and nontargeted liposomes was 6.4-fold and 8.3-fold higher than that of doxorubicin solution, respectively. Conclusion This study indicates preferential targeting and long circulating properties for cRGD-modified liposomes in vivo, which could be used as a potential targeted liposomal drug delivery system to treat human glioma.
A Common Runtime for High Performance Data Analysis

Modern analytics applications combine multiple functions from different libraries and frameworks to build increasingly complex workﬂows. Even though each function may achieve high performance in isolation, the performance of the combined workﬂow is often an order of magnitude below hardware limits due to extensive data movement across the functions. To address this problem, we propose Weld, a runtime for data-intensive applications that optimizes across disjoint libraries and functions. Weld uses a common intermediate representation to capture the structure of diverse data-parallel workloads, including SQL, machine learning and graph analytics. It then performs key data movement optimizations and generates efﬁcient parallel code for the whole workﬂow. Weld can be integrated incrementally into existing frameworks like Tensor-Flow, Apache Spark, NumPy and Pandas without changing their user-facing APIs. We show that Weld can speed up these frameworks, as well as applications that combine them, by up to 30 × .
Primary argon laser trabeculoplasty vs. pilocarpine Short‐term effects

Abstract This is a prospective study of 82 newly discovered patients with simplex or capsular glaucoma from two centres, collected between 1984 and 1989 and selected at random for primary treatment by either laser or pilocarpine. Preliminary two‐year follow‐up shows that primary laser treatment gives a significantly higher number of patients where the intraocular pressure is successfully controlled. Primary argon laser trabeculoplasty has been carried out in 40 patients. The first treatment was given to either the upper or to the lower half of the trabecular meshwork. In the second treatment after one month the other half was treated. In both groups the first treatment gave the highest pressure reduction. The somewhat higher pressure reduction after upper treatment versus lower was insignificant. The degree of trabecular pigmentation did not influence the two month follow‐up result, neither did the type of glaucoma. Of the eyes treated with laser, peripheral anterior synechiae could be seen in 18%. Acute intraocular pressure rises greater than 5 mmHg occurred in 21% of the eyes after the first treatment and in 37% after the second treatment. Pressure rises greater than 10 mmHg occurred in 5% after the first and in 10% after the second treatment. No pressure‐lowering substances were given. Considering that 16% of the eyes had an intraocular pressure that was higher than baseline pressure even 6 h after either first or second treatment, it is recommended that a pressure‐lowering medication on the day of treatment should be administered.
Halo mass function and scale-dependent bias from N-body simulations with non-Gaussian initial conditions

We perform a series of high-resolution N-body simulations of cosmological structure formation starting from Gaussian and non-Gaussian initial conditions. We adopt the best-fitting cosmological parameters from the third- and fifth-year data releases of the Wilkinson Microwave Anisotropy Probe, and we consider non-Gaussianity of the local type parametrized by eight different values of the non-linearity parameter f NL . Building upon previous work based on the Gaussian case, we show that, when expressed in terms of suitable variables, the mass function of friends-of-friends haloes is approximately universal (i.e. independent of redshift, cosmology and matter transfer function) to good precision (nearly 10 per cent) also in non-Gaussian scenarios. We provide fitting formulae for the high-mass end (M > 10 13 h -1 M ⊙ ) of the universal mass function in terms of f NL , and we also present a non-universal fit in terms of bothfN L and z to be used for applications requiring higher accuracy. For Gaussian initial conditions, we extend our fit to a wider range of halo masses (M > 2.4 x 10 10 h -1 M ⊙ ) and we also provide a consistent fit of the linear halo bias. We show that, for realistic values of f NL , the matter power spectrum in non-Gaussian cosmologies departs from the Gaussian 1 by up to 2 per cent on the scales where the baryonic-oscillation features are imprinted on the two-point statistics. Finally, using both the halo power spectrum and the halo-matter cross spectrum, we confirm the strong k-dependence of the halo bias on large scales (k < 0.05 h Mpc 1- ) which was already detected in previous studies. However, we find that commonly used parametrizations based on the peak-background split do not provide an accurate description of our simulations which present extra dependencies on the wavenumber, the non-linearity parameter and, possibly, the clustering strength. We provide an accurate fit of the simulation data that can be used as a benchmark for future determinations of f NL with galaxy surveys.
Durational properties of emphatically lengthened consonants in Japanese

Languages can make use of phonetic duration to signal two kinds of meanings. The first is a lexical, phonological contrast. For example, in Japanese [kata] with a short [t] means ‘frame’ and [katta] with a long [tt] means ‘bought’. This sort of contrast is usually limited to a binary distinction, and its phonetic properties have been well studied for many diverse languages. The other use of phonetic duration is to express pragmatic emphasis. Speakers of some languages can use lengthening to express emphasis, as in the English example Thank you sooooooo much. This lengthening can employ multiple degrees of duration, beyond the more standard binary contrast. This second use of duration has been understudied, and this paper attempts to fill that gap. To that end, this paper reports the first experimental documentation of the consonant lengthening pattern in Japanese, which expresses pragmatic emphasis. The results show that at least some speakers show six levels of durational distinctions, while other speakers show less clear-cut distinctions among different levels of emphatically lengthened consonants. Nevertheless, all but one speaker showed a linear correlation between duration and level of emphasis.
Use of Fluorescence, a Novel Technique to Determine Reduction in Bemisia tabaci (Hemiptera: Aleyrodidae) Nymph Feeding When Exposed to Benevia and Other Insecticides

ABSTRACT The sweet potato whitefly, Bemisia tabaci (Gennadius), is an economically important pest in the United States and other countries. Growers in many places rely on the use of insecticides to reduce populations of B. tabaci. However, insecticides may take a few days to cause B. tabaci mortality and some do not reduce feeding before death. Earlier reduction of feeding of whiteflies would decrease the physiological effects on plants, reduce the production of sooty mold and potentially reduce the transmission of viruses. Measuring the reduction in feeding after the exposure of B. tabaci to an insecticide has proven difficult. This series of laboratory experiments demonstrate the usefulness of fluorescence in determining B. tabaci feeding cessation. Fluorescein sodium salt is systemically transported in the xylem from the roots to the plant leaves and absorbed by B. tabaci nymphs feeding on these plants. Nymphs start fluorescing shortly after the cotton plant root system is submerged in the fluorescein sodium salt. Using this novel technique, the effect of three insecticides with different modes of action, cyantraniliprole, imidacloprid, and spirotetramat on B. tabaci was evaluated and compared to determine reduction in feeding. Results indicate that B. tabaci nymphs feeding on a plant treated with Benevia have a significant reduction of feeding when compared with nymphs feeding on plants treated with imidacloprid or spirotetramat. Both Benevia and spirotetramat caused significant nymphal mortality by 48 h after exposure. This novel technique will be useful to demonstrate the feeding cessation or reduction in feeding produced by different insecticides in several sucking insect groups.
Expectation Enhances the Regional Brain Metabolic and the Reinforcing Effects of Stimulants in Cocaine Abusers

The reinforcing effects of drugs of abuse result from the complex interaction between pharmacological effects and conditioned responses. Here we evaluate how expectation affects the response to the stimulant drug methylphenidate in 25 cocaine abusers. The effects of methylphenidate (0.5 mg/kg, i.v.) on brain glucose metabolism (measured by [18F]deoxyglucose-positron emission tomography) and on its reinforcing effects (self-reports of drug effects) were evaluated in four conditions: (1) expecting placebo and receiving placebo; (2) expecting placebo and receiving methylphenidate; (3) expecting methylphenidate and receiving methylphenidate; (4) expecting methylphenidate and receiving placebo. Methylphenidate increased brain glucose metabolism, and the largest changes were in cerebellum, occipital cortex, and thalamus. The increases in metabolism were ∼50% larger when methylphenidate was expected than when it was not, and these differences were significant in cerebellum (vermis) and thalamus. In contrast, unexpected methylphenidate induced greater increases in left lateral orbitofrontal cortex than when it was expected. Methylphenidate-induced increases in self-reports of “high” were also ∼50% greater when subjects expected to receive it than when they did not and were significantly correlated with the metabolic increases in thalamus but not in cerebellum. These findings provide evidence that expectation amplifies the effects of methylphenidate in brain and its reinforcing effects. They also suggest that the thalamus, a region involved with conditioned responses, may mediate the enhancement of the reinforcing effects of methylphenidate by expectation and that the orbitofrontal cortex mediates the response to unexpected reinforcement. The enhanced cerebellar activation with expectation may reflect conditioned responses that are not linked to conscious responses.
Real-Time Augmented Reality for Robotic-Assisted Surgery

Training in robotic-assisted minimally invasive surgery is crucial, but the training with actual surgery robots is relatively expensive. Therefore, improving the efficiency of this training is of great interest in robotic surgical education. One of the current limitations of this training is the limited visual communication between the instructor and the trainee. As the trainee’s view is limited to that of the surgery robot’s camera, even a simple task such as pointing is difficult. We present a compact system to overlay the video streams of the da Vinci surgery systems with interactive three-dimensional computer graphics in real time. Our system makes it possible to easily deploy new user interfaces for robotic-assisted surgery training. The system has been positively evaluated by two experienced instructors in robot-assisted surgery.
Effective Pākehā teachers of Māori Students

To teach in primary schools in Aotearoa-New Zealand means to encounter students from diverse backgrounds. A significant proportion of those students are M a ori and a significant proportion of M a ori students are not achieving to their potential in school. There are several reasons for this under-achievement, which this thesis explores, and there is substantial research evidence as to what will turn this situation around, which is also explored. Some argue that the answer is for M a ori learners to be taught by M a ori teachers, and in M a ori medium contexts. This approach has achieved considerable success for a small number of M a ori learners; however, the demographic data tell us that for now, the significant majority of M a ori learners are in English language medium classrooms, taught by non-M a ori teachers. At present, there are not enough M a ori teachers to teach all M a ori learners. The New Zealand Ministry of Education has goals for improving the achievement of M a ori learners through providing “high-quality, culturally responsive education that incorporates the identity, language and culture of M a ori students, and engages their parents, families and wh a nau” (Ministry of Education, 2008). The Ministry and the New Zealand Teachers Council expect all teachers to be ‘culturally competent’, that is, to teach in culturally responsive ways. The Ministry of Education’s research and development project, Te K o tahitanga, continues to provide evidence of ‘what works’ for M a ori learners in New Zealand secondary schools. The effective teaching profile that was developed as part of this project informs this thesis. The thesis describes qualitative, social justice-based case study research undertaken between late 2004 and 2006 with four effective P a keh a primary teachers of M a ori children, and with children from those classes and their parents/wh a nau. The study sought to glean insights about what characterises effective P a keh a primary teachers of M a ori students.