Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficacy of telavancin, a lipoglycopeptide antibiotic, in experimental models of Gram-positive infection

Telavancin is a parenteral lipoglycopeptide antibiotic with a dual mechanism of action contributing to bactericidal activity against multidrug-resistant Gram-positive pathogens. It has been approved for the treatment of complicated skin and skin structure infections due to susceptible Gram-positive bacteria and hospital-acquired/ventilator-associated bacterial pneumonia due to Staphylococcus aureus when other alternatives are unsuitable. Telavancin has been demonstrated to be efficacious in multiple animal models of soft tissue, cardiac, systemic, lung, bone, brain and device-associated infections involving clinically relevant Gram-positive pathogens, including methicillin-resistant S. aureus, glycopeptide-intermediate S. aureus, heterogeneous vancomycin-intermediate S. aureus and daptomycin non-susceptible methicillin-resistant S. aureus. The AUC0–24h/MIC ratio is the primary pharmacodynamically-linked pharmacokinetic parameter. The preclinical data for telavancin supports further investigative clinical evaluation of its efficacy in additional serious infections caused by susceptible Gram-positive pathogens.
IL-Miner: Instance-Level Discovery of Complex Event Patterns

Complex event processing (CEP) matches patterns over a continuous stream of events to detect situations of interest. Yet, the definition of an event pattern that precisely characterises a particular situation is challenging: there are manifold dimensions to correlate events, including time windows and value predicates. In the presence of historic event data that is labelled with the situation to detect, event patterns can be learned automatically. To cope with the combinatorial explosion of pattern candidates, existing approaches work on a type-level and discover patterns based on predefined event abstractions, aka event types. Hence, discovery is limited to patterns of a fixed granularity and users face the burden to manually select appropriate event abstractions. We present IL-Miner, a system that discovers event patterns by genuinely working on the instance-level, not assuming a priori knowledge on event abstractions. In a multi-phase process, IL-Miner first identifies relevant abstractions for the construction of event patterns. The set of events explored for pattern discovery is thereby reduced, while still providing formal guarantees on correctness, minimality, and completeness of the discovery result. Experiments using real-world datasets from diverse domains show that IL-Miner discovers a much broader range of event patterns compared to the state-of-the-art in the field.
Notes on Countertransference

wo CONTRASTING approaches in regard to the concept of countertransference could be described. Let us call the first approach T the “classical” one, and define its concept of countertransference as the unconscious reaction of the psychoanalyst to the patient’s transference. This approach stays close to the use of the term as first proposed by Freud (8) and to his recommendation that the analyst overcome his countertransference (9). This approach also tends to view neurotic conflicts of the analyst as the main origin of the countertransference. Let us call the second approach the “totalistic” one; here countertransference is viewed as the total emotional reaction of the psychoanalyst to the patient in the treatment situation. This school of thought believes that the analyst’s conscious and unconscious reactions to the patient in the treatment situation are reactions to the patient’s reality as well as to his transference, and also to the analyst’s own reality needs as well as to his neurotic needs. This second approach also implies that these emotional reactions of the analyst are intimately fused, and that although countertransference should certainly be resolved, it is useful in gaining more understanding of the patient. In short, this approach uses a broader definition of countertransference and advocates a more active technical use of it. Some radical proponents of this approach
Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis

Summary A multicenter study was set up to evaluate the prevalence, clinical and biological significance of antiphosphatidylethanolamine antibodies (aPE) in thrombotic patients with or without the main known clinical and biological risk factors for thrombosis. APE and antibodies, defined as the laboratory criteria of antiphospholipid syndrome (APS) -lupus anticoagulant, anticardiolipin and anti-beta2-GPI antibodies were measured in 270 patients with thrombosis (234 venous and 37 arterial) and 236 matched controls. APE were found in 15% of thrombotic patients compared to 3% of controls (p<0.001) with no predominant isotype, no association with the main known clinical or biological risk factors for thrombosis neither with a type of thrombosis, arterial or venous. In a multivariate logistic regression analysis of antibodies, aPE showed the highest association with thrombosis (odds ratio [OR]: 4.2, p<0.001). Moreover, using a multivariate analysis in a case-control subgroup study on 158 patients, IgGaPE were found to be significantly associated with venous thrombosis (OR:6;p=0.005). Interestingly, 25 of the 40 aPE-positive patients (63%) were negative for the APS laboratory criteria. Most of them (21/25) had venous thrombosis, recurrent in ten of them. Four patients also suffered from early or late miscarriages. Our results underline the strength of the association between the presence of aPE and thrombosis and suggest their measurement in thrombotic patients, especially when lupus anticoagulant, anticardiolipin or anti-beta2-GPI antibodies are absent.
Effects of Cultural Collectivism on Terrorism Favorability

Cultural orientation has long been known to play a substantial role in the decisions individuals make on a range of subjects. This research proposes that participation in acts defined as “terrorism” is strongly correlated to an individual's cultural orientation to collective values. Drawing upon Geehrt Hofstede's extensive work on culture, collectivism describes integration into strong, cohesive in-groups which offer protection in exchange for unquestioning loyalty. Considering the overlap between this cultural perspective and the motivations for participation in terrorism, we hypothesize that acts of terrorism will be more prevalent in cultures Hofstede identifies as highly collective. Utilizing the Worldwide Incidents Tracking System (WITS), we identified events where the nationality of perpetrators was known. A correlation analysis with Hofstede's measure of national collective culture was conducted. Given the inconsistent results generated by militaristic and invasive counter-terrorism strategies, an emphasis on creating programs for collective cultures that are locally appropriate is suggested. Limitations and implications of the study are highlighted.
Fluoxetine Treatment of Depressed Patients with HIV Infection

Objective: The aim of this paper is to describe the outcome of fluoxetine treatment of depressed patients with HIV infection. Method: An open study was made of 20 patients with varying stages of HIV infection treated for depression with fluoxetine. Results: 15 of 20 patients improved with fluoxetine treatment; the drug was generally well tolerated, with no significant drug-drug interactions. Conclusions: Fluoxetine appears to be effective for the treatment of depression in patients with HIV infection.
AN INVESTIGATION INTO THE PSYCHOMETRIC PROPERTIES OF THE COGNITIVE THERAPY SCALE FOR PSYCHOSIS (CTS-Psy)

Recent research suggests that cognitive-behaviour therapy (CBT) can significantly improve outcomes for patients with severe mental health problems. However, there are no tools specifically designed to assess competence in delivering CBT to psychotic patients. This study investigates the psychometric properties of the Cognitive Therapy Scale for Psychosis (the CTS-Psy) for assessing the quality of CBT with psychotic patients. Inter-rater reliability of trained raters using the CTS-Psy was investigated using taped therapy of trainees engaged in a CBT oriented psychosis training course. Validity was investigated in relation to examining the degree to which the scale could be used to assess a range of therapist ability and patient severity and by assessing the degree to which the CTS-Psy could pick up changes in skill acquisition during the training course over a 9-month period. The CTS-Psy demonstrated excellent inter-rater reliability and good validity in relation to it being able to rate all standards of therapy and all types of patient sessions in the sample studied. In addition, the scale was sensitive to changes in clinical skills during a training course and could discriminate between those who had received training and those who had not.
Color text extraction from camera-based images: the impact of the choice of the clustering distance

Character recognition has a continuous importance for several years and recently, new challenges appeared with camera-based pictures. This paper deals with text extraction for color natural scenes images. Many papers try to combine several color spaces or to choose the best one for a particular database. We show that the main problem is not in the choice of color spaces for generic text extraction but in the choice of clustering distances to handle alt degradations present in this kind of images. Comparative results are given using a public database.
Indigenous Pedagogy as a Force for Change

Abstract Indigenous academics over the past decade and a half have been focusing strongly, in terms of theory development, on Indigenous epistemologies and research methodologies. What has not been given equal academic attention is the theoretical articulation of Indigenous pedagogy, not only as a valid system of knowledge and skill transfer, but also as one that conveys meaning, values and identity. In this paper, we want to explore some of the practical aspects of Indigenous pedagogy in a tertiary setting by way of a student-teacher dialogue and also discuss the wider implications of a theoretical articulation from our perspective as researchers and academics. We argue that at the intersection of the discourses on transformative pedagogy and Indigenous education in Australia lays an unexplored concept which, properly articulated and implemented, could have great benefits for all learners. Having been afforded attention elsewhere, particularly in North America, it is time to discuss Indigenous pedagogy as a teaching methodology based on Indigenous values and philosophies in Australia today.
Strong convergence of the empirical distribution of eigenvalues of large dimensional random matrices

Let X be n - N containing i.i. d. complex entries with E X11 - EX112 = 1, and T an n - n random Hermitian nonnegative definite, independent of X. Assume, almost surely, as n --> [infinity], the empirical distribution function (e.d.f.) of the eigenvalues of T converges in distribution, and the ratio n/N tends to a positive number. Then it is shown that, almost surely, the e.d. f. of the eigenvalues of (1/N) XX*T converges in distribution. The limit is nonrandom and is characterized in terms of its Stieltjes transform, which satisfies a certain equation.
Sport and Belonging

Even though it is a common understanding among policymakers that playing sport creates feelings of belonging to a community, there is little research that confirms this assumption. The present article focuses on the relationship between sport and belonging. The study is based on life history interviews with 21 young Norwegian Muslim women with immigrant backgrounds, aged between 16 and 25 years. The article suggests that there are different forms of belonging produced through sport. The analysis separates between traditional sport communities that produce social support and more expressivity based sport communities that contribute to identity confirmation and self-image building. Moreover, the article points to the finding that young Muslim women experience a sense of belonging within sports because playing sports is sometimes perceived as a `place of refuge'.
Signs of Recognition

Webb Keane argues that by looking at representations as concrete practices we may find them to be thoroughly entangled in the tensions and hazards of social existence. This book explores the performances and transactions that lie at the heart of public events in contemporary Anakalang, on the Indonesian island of Sumba. Weaving together sharply observed narrative, close analysis of poetic speech and valuable objects, and far-reaching theoretical discussion, Signs of Recognition explores the risks endemic in representational practices. An awareness of risk is embedded in the very forms of ritual speech and exchange. The possibilities for failure and slippage reveal people's mutual vulnerabilities and give words and things part of their power. Keane shows how the dilemmas posed by the effort to use and control language and objects are implicated with general problems of power, authority, and agency. He persuades us to look differently at ideas of voice and value. Integrating the analysis of words and things, this book contributes to a wide range of fields, including linguistic anthropology, cultural studies, social theory, and the studies of material culture, art, and political economy.
Inference of Brain Mental States from Spatio-temporal Analysis of EEG Single Trials

We present an efficient and robust computational model for brain state interpretation from EEG single trials. This includes identification of the most relevant time points and electrodes that may be active and contribute to differentiation between the mental states investigated during the experiment. The model includes a regularized logistic regression classifier trained with cross-validation to find the optimal model and its regularization parameter. The proposed framework is generic and can be applied to different classification tasks. In this study we applied it to a classical visual task of distinction between faces and houses. The results show that the obtained single trial prediction is significantly better than chance. Moreover, correct choice of the regularization parameter significantly improves classification results. In addition, the obtained spatial-temporal information of brain activity can give an indication to correlated activity of regions of the brain (spatial) as well as temporal activity correlations between and within EEG electrodes. This spatialtemporal analysis can render a far more holistic interpretability for visual perception mechanism without any a priori bias on certain time periods or scalp locations.
New Kludge scheme for the construction of approximate waveforms for extreme-mass-ratio inspirals

We introduce a new kludge scheme to model the dynamics of generic extreme mass-ratio inspirals (stellar compact objects spiraling into a spinning supermassive black hole) and to produce the gravitational waveforms that describe the gravitational-wave emission of these systems. This scheme combines tools from different techniques in General Relativity: It uses a multipolar, post-Minkowskian (MPM) expansion for the far-zone metric perturbation (which provides the gravitational waveforms, here taken up to mass hexadecapole and current octopole order) and for the local prescription of the self-force (since we are lacking a general prescription for it); a post-Newtonian expansion for the computation of the multipole moments in terms of the trajectories; and a BH perturbation theory expansion when treating the trajectories as a sequence of self-adjusting Kerr geodesics. The orbital evolution is thus equivalent to solving the geodesic equations with time-dependent orbital elements, as dictated by the MPM radiation-reaction prescription. To complete the scheme, both the orbital evolution and wave generation require to map the Boyer-Lindquist coordinates of the orbits to the harmonic coordinates in which the different MPM quantities have been derived, a mapping that we provide explicitly in this paper. This new kludge scheme is thus a combination of approximations that can be used to model generic inspirals of systems with extreme mass ratios to systems with more moderate mass ratios, and hence can provide valuable information for future space-based gravitational-wave observatories like LISA and even for advanced ground detectors. Finally, due to the local character in time of our MPM self-force, this scheme can be used to perform studies of the possible appearance of transient resonances in generic inspirals.
“Diamond in the Rough”: The Impact of a Remedial Program on College Access and Opportunity for Black Males at an Historically Black Institution

Researchers, policymakers, and administrations have shown great concern over the efficacy of college remediation, which has prompted some states to eliminate remedial programs from public 4–year institutions. However, research suggests that eliminating these programs may have unintended consequences on college access and opportunity for underrepresented minority students, particularly African Americans. This study explores the impact of a remedial program on 11 African-American male students at a public 4–year historically Black institution. Findings illuminate the importance of college remediation in promoting college access and opportunity for underprepared Black male students, and how remedial programs increase academic and social integration for these students.
Bayesian Comparison of Several Continuous Time Models of the Australian Short Rate

This paper provides an empirical analysis of a range of alternative single-factor continuous time models for the Australian short-term interest rate. The models are nested in a general single-factor diffusion process for the short rate, with each alternative model indexed by the level effect parameter for the volatility. The inferential approach adopted is Bayesian, with estimation of the models proceeding through a Markov chain Monte Carlo simulation scheme. Discrimination between the alternative models is based on Bayes factors. A data augmentation approach is used to improve the accuracy of the discrete time approximation of the continuous time models. An empirical investigation is conducted using weekly observations on the Australian 90 day interest rate from January 1990 to July 2000. The Bayes factors indicate that the square root diffusion model has the highest posterior probability of all models considered.
Drugs, hopes and dreams: appreciative inquiry with marginalized young people using drugs and alcohol

Drugs and alcohol misuse in young people is a major public health problem with substantial levels of morbidity and mortality. Social, economic and cultural factors play a major part in the initiation and maintenance of substance misuse in young people. Many young people who misuse drugs have multiple antecedent and co-occurring mental health problems, unrecognized learning difficulties, family difficulties and deeply entrenched social problems. Given the heterogeneity of the patterns of substance misuse in these young people, and the potential for persistence of serious problems into their adult lives, a range of interventions should be developed to address the risk factors across biological, psychological and social domains. Family/systemic interventions provide the best outcomes for young people with substance misuse, though even the most intensive forms of systemic therapies may fall short of producing enduring changes, especially for marginalized young people and communities. Appreciative inquiry (AI) is one of the most significant innovations in action research in the past decade and a method of producing long-lasting changes to the larger social system. AI is an attempt to generate a collective image of a new and better future by exploring the best of what is and has been. We describe an anecdotal experience of using AI in producing long-lasting changes in a group of marginalized young people in South Africa, who were engaged in drug and alcohol misuse and antisocial behaviour. The principles and practice of AI are described in detail, followed by a discussion of the implications of these findings for a UK population.
Complications on a general surgery service: incidence and reporting.

OBJECTIVES To determine the incidence and nature of complications on a general surgery service and to compare these results with pre-existing institutional recording and reporting methods. DESIGN A single observer prospectively monitored the presence and documentation of complications for all patients admitted to the general surgery service at the Wellesley Central Hospital over a 2-month period, through daily chart reviews, attendance at rounds and surgical operating rooms, frequent patient visits on the ward and interviews with the health care team. SETTING The general surgery service of an urban, university-affiliated teaching hospital. PATIENTS One hundred and ninety-two general surgery inpatients over 1277 patient-days from June 16, 1996, until Aug. 15, 1996. Same-day surgery patients were not included. RESULTS Seventy-five (39%) of the 192 patients suffered a total of 144 complications. Two complications (1%) were fatal, 10 (7%) were life threatening, 90 (63%) were of moderate severity and 42 (29%) were trivial. Of these 144 complications, 26 (18%) were deemed potentially attributable to error. One hundred and twelve (78%) of the complications occurred during or after a surgical operation and were related directly or indirectly to it. Only 9 (6%) complications were not documented in the progress notes of the patients' charts. However, 115 (80%) were not presented at weekly morbidity and mortality rounds, and 95 (66%) were not documented on the face sheet of the patients' final medical records. CONCLUSIONS Complications are common and are underreported by traditional methods. Since hospital funding and quality improvement efforts depend on accurate identification and recording of adverse events, strategies to improve the recording and reporting of complications must be developed.
Measuring the 3-D Flow of the Lowell Glacier with InSAR

| In this paper, we use single and dualpass satellite-based interferometric radar to measure the ow magnitude of a large alpine glacier. Since the radar measurements alone are not su cient to resolve the 3-D ow direction of the glacier, several ow directions assumptions are made, and checked for mutual consistency. The assumptions that the horizontal component of ow is parallel to the medial moraine, and that the ow is parallel to the glacier surface give the best results over most of the glacier. With one or both of these assumptions, we are able to measure the glacier ow along its centreline to an accuracy of approximately 3 cm/day.
LEADERSHIP TRAINING IN ORGANIZATIONAL JUSTICE TO INCREASE CITIZENSHIP BEHAVIOR WITHIN A LABOR UNION: A REPLICATION

In a replication of a quasi-experiment by Skarlicki and Latham (1996), we investigated the effect of training union leaders (N= 25) in the administration of organizational justice principles on union members' (N= 177) perceptions of their leaders' fairness and the members' subsequent citizenship behavior toward their union. Despite the fact that the union members were also shareholders of the company, the results were replicated. Union leader training increased members' perceptions of their leaders' fairness as well as union members' citizenship behavior directed both toward the union as an organization (OCBO) and fellow union members (OCBI). Organizational justice was found to partially mediate the effect of the training on OCBO, but not OCBI.