Miracle-dz/UniFAR-FTUs huggingface dataset:
When Virtual Meets Physical at the Edge

The wide deployment of virtualization in datacenters catalyzes the emergence of virtual traffic that delivers the network demands between the physical network and the virtual machines hosting clients' services. Virtual traffic presents new opportunities for reducing physical network demands, as well as challenges of increasing management complexity. Given the plethora of prior art on virtualization technologies in datacenters, surprisingly little is still known about such virtual traffic, and its dependence on the physical network and virtual machines. This paper provides a multi-faceted analysis of the patterns and impacts of multiplexing the virtual traffic onto the physical network, particularly from the perspective of the network edge. We use a large collection of field data from production datacenters hosting a large number of diversified services from multiple enterprise tenants. Our first focus is on uncovering the temporal and spatial characteristics of the virtual and physical traffic, i.e., network demand growth and communication patterns, with special attention paid to the traffic of migrating virtual machines. The second focus is on characterizing the effect of network multiplexing in terms of communication locality, traffic load heterogeneity, and the dependency on CPU processing power at the edges of the network. Last but not least, we conduct a mirroring analysis on service QoS, defined by the service unavailability induced by network related issues, e.g., loads. We qualitatively and quantitatively discuss the implications and opportunities that virtual traffic presents for network capacity planning of virtualized networks and datacenters.
[Frequency analysis of NOD2 gene mutations in Korean patients with Crohn's disease].

BACKGROUND/AIMS Several studies from Western populations have recently shown that three mutations in NOD2 gene (C2104T, G2722C, and 3020insC) are associated with susceptibility to Crohn's disease (CD). However, three mutations were shown not to be associated with CD in Japanese and Chinese population. Here, we have analyzed the frequency of three NOD2 mutations in Korean patients to determine whether the NOD2 mutations are associated with susceptibility to CD in Korean population. METHODS Blood samples were obtained from 128 patients with CD, 47 patients with ulcerative colitis, 19 Behcet's colitis, and 200 healthy controls. DNA in the region of three NOD2 mutations was sequenced by single base extension method, and the frequency of mutations were analyzed. RESULTS Among the subjects in our study groups, including patients with CD, ulcerative colitis, Behcet's colitis, and healthy controls, none had NOD2 mutations. CONCLUSIONS Our results indicate that although three NOD2 mutations are associated with susceptibility to CD in Western populations, these might be rare and may not be associated with susceptibility to CD in Korean patients.
Rethinking the Logics: A Conceptual Framework for the Mediatization of Politics

This article suggests a conceptual framework for the mediatization of politics. It critically discusses the concepts of “media logic” and “political logic” emanating from the political communication literature and argues that “normative logic” and “market logic” are more appropriate concepts for the theoretical understanding and empirical analysis of the behavior of mass media and political actors. These two logics guide media and political actors' issue selection and presentation to different degrees. The mediatization of politics in this account takes place when both media and political actors adapt their behavior to the audience-oriented market logic. This process works in parallel with the economic integration and technological progress comprised by the term globalization, thereby challenging established institutional mechanisms in advanced democracies.
Category predication work, discursive leadership and strategic sensemaking

Categorization is known to play an important role in organizations because categories ‘frame’ situations in particular ways, informing managerial sensemaking and enabling managerial intervention. In this article, we advance existing work by examining the role of categorization practices in discursive leadership during periods of strategic change. Drawing on data from an ethnographic action research study of a strategic change initiative in a multi-national corporation, we use membership categorization analysis to develop a framework for studying ‘category predicates’ − defined as the stock of organizational knowledge and associated reasoning procedures concerning the kinds of activities, attributes, rights, responsibilities, expectations, and so on, that are ‘tied’ or ‘bound’ to organizational categories. Our analysis shows that discursive leadership enabled a radical shift in sensemaking about organizational structure categories through a process of ‘frame-breaking’ and ‘re-framing’. In so doing, the leader co-constructed a ‘definition of the situation’ that built a compelling vision and concrete plan for strategic change. We go on to trace the organizational consequences and material outcomes of this shift in sensemaking for the company in question. We conclude by arguing that ‘category predication work’ comprises a key leadership competence and plays an important role in organizational and strategic change processes.
Cognitive and Academic Functioning in Children With Sickle-Cell Disease

Comparing cognitive processing and academic functioning among children with sickle-cell syndrome and nondiseased siblings who were comparable in age, socioeconomic status, and sex, this study found that children with sickle-cell syndrome scored significantly lower than nondiseased siblings on a reading decoding achievement test and a sustained attention task associated with frontal-lobe functioning. No support was found for either the hypothesis of an age-related decrement of cognitive functioning or the hypothesis that youth with the homozygous condition (HbSS) would perform more poorly on cognitive and academic tasks than would children with heterozygous forms of sickle-cell syndrome (HbSC and HbS-beta thalassemia). The majority of measures were, however, related to social class, suggesting that there is variability in the cognitive functioning of youth in whom sickle-cell disease had been diagnosed which may, in part, be attributed to social class. The finding that hemoglobin is a predictor of intellec.
Toward a self-organizing pre-symbolic neural model representing sensorimotor primitives

The acquisition of symbolic and linguistic representations of sensorimotor behavior is a cognitive process performed by an agent when it is executing and/or observing own and others' actions. According to Piaget's theory of cognitive development, these representations develop during the sensorimotor stage and the pre-operational stage. We propose a model that relates the conceptualization of the higher-level information from visual stimuli to the development of ventral/dorsal visual streams. This model employs neural network architecture incorporating a predictive sensory module based on an RNNPB (Recurrent Neural Network with Parametric Biases) and a horizontal product model. We exemplify this model through a robot passively observing an object to learn its features and movements. During the learning process of observing sensorimotor primitives, i.e., observing a set of trajectories of arm movements and its oriented object features, the pre-symbolic representation is self-organized in the parametric units. These representational units act as bifurcation parameters, guiding the robot to recognize and predict various learned sensorimotor primitives. The pre-symbolic representation also accounts for the learning of sensorimotor primitives in a latent learning context.
Utility of galectin-3 as a prognostic biomarker in heart failure: where do we stand?

Background Heart failure (HF) continues to be an illness of daunting proportions with a four- year mortality touching 50%. Biomarkers for prognosticating patients with heart failure have generated immense interest. Several studies have been conducted on a novel biomarker, galectin-3 to assess its prognostic effect in heart failure populations. However, the studies have generated conflicting results. Hence a systematic review was done to assess the utility of galectin-3 as a prognostic biomarker in HF. Design This study was a systematic review. Methods A literature search was done using terms ‘galectin-3 and heart' and ‘galectin-3 and heart failure' in MEDLINE, Science Direct, Scopus, Springer Link, Cochrane Library and Google Scholar for original articles using a predefined inclusion/exclusion criteria. Results Altogether 27 original articles were selected for the systematic review. Multivariate analysis showed galectin-3 to be ineffective in predicting all-cause mortality and cardiovascular mortality especially under the influence of factors such as estimated glomerular filtration rate (eGFR), left ventricular ejection fraction (LVEF) and N-terminal pro-B-type natriuretic peptide (NTproBNP). Galectin-3 was not found to be superior to NTproBNP, sST2, GDF-15 or C-reactive protein (CRP) as a predictor of mortality. However the combination of natriuretic peptides and galectin-3 has been observed to be superior in predicting mortality compared to either of the biomarkers alone. The role of galectin-3 in remodelling has not been conclusively proven as seen in earlier pre-clinical studies. Conclusion The current weight of evidence does not suggest galectin-3 to be a predictor of mortality. However, assessment of galectin-3 in a multi-biomarker panel may have a distinct advantage in prognosticating patients with heart failure.
Prevalência dos transtornos mentais na população adulta brasileira: uma revisão sistemática de 1997 a 2009

INTRODUCTION: This systematic review of literature aims to verify prevalence rates of mental disorders in the Brazilian adult population. METHODS: We searched the Medline and Lilacs in the period from 1997 to 2009 using the following descriptors: "mental disorders", "cross-section studies", "Brazil". Exclusion criteria of articles were: no abstract, no description of cross-sectional study, did not contain the estimate that would verify the prevalence of mental disorders, studies with specific populations and further studies with children, adolescents and elderly, and written in other languages other than Portuguese, English and Spanish. These criteria resulted in the selection of 25 articles. RESULTS: In the studies reviewed found high rates of overall prevalence of mental disorders in adults. These rates varied between 20% and 56%, affecting mainly women and workers. DISCUSSION: The studies analyzed in this review show an overview of mental disorders in Brazilian adult population, describing how is their distribution in this population, pointing to high rates, often associated with sex, age, socioeconomic, work conditions and lifestyles of individuals.
Predicting Worker Turnover: An Assessment of Intent on Actual Separations

The predictive ability of most turnover models emanates from a key construct measuring a worker's intention to withdraw from a work organization. Empirical evidence to collaborate this cardinal assumption has, however, only moderate support. To test the predictive value of intention to leave, a logistic regression model of combined cross-sectional and longitudinal survey data on workers'potential and actual turnover was initiated. The results demonstrate that actual turnover and intent are influenced by a separate set of factors with intent a poor predictor of turnover behavior. Age, tenure, wage level, and perceived chances for improvement at the job were found to have a significant impact on actual separation, but not on the intent to leave. Work repetitiveness, importance of improvement, and perception of co-workers' intent influence the intent to move, but not turnover. Perception of co-workers' intentions to leave and importance of improvement played a dual role for both intent and turnover, but much more so for intentions. Further confirmation of these differences was sought by in/excluding intentions into the logistic regression of all the independent variables on actual separation. No improvement in the model occurred indicating the negligible impact of intent on explaining turnover. A parsimonious regression equation to optimize prediction of actual turnover was created, leading to a high and low risk leaver-stayer profile with probabilities ranging from 85.3% to 3.9%. The overall conclusion confirms the distinctiveness of intention and turnover as distinct constructs which are only superficially linked. As they differ in their basic explanatory antecedents, only variables linked to turnover predict work separations. Intentions do not.
Temporal Variations of Coagulation Factor VII Activity in Mice Are Influenced by Lighting Regime

It was recently reported that the circadian clock machinery controls plasma levels of factor (F) VII, the serine protease triggering blood coagulation. Here, by exploiting the mouse model, this study showed that variations of photoperiod (i.e., winter or summer conditions or simulated chronic jetlag conditions) have a strong impact on plasma FVII activity levels. Under conditions mimicking summer or winter photoperiods, FVII activity showed a clear 24 h rhythmicity. Interestingly, mean daily FVII activity levels were significantly reduced in mice exposed to summer photoperiods. Behavioral activity rhythms under both photoperiods were synchronized to LD cycles, and the amount of activity per 24 h was comparable. The authors also investigated the influence of chronic jetlag (CJL) on the FVII activity rhythms, which can be easily mimicked in mice through continuous abrupt shifts in the lighting schedule. The exposure of mice to simulated CJL of either consecutive westward or consecutive westward and eastward flights for 15 days did not abolish the behavioral activity rhythms but was associated with a period significantly different from 24 h. Intriguingly, both types of CJL exerted a strong influence on FVII activity rhythms, which were virtually suppressed. Moreover, the mean daily FVII activity was significantly lower in the CJL than in the winter photoperiod condition. Taken together, these findings in mice provide novel insights into the modulation of FVII activity levels, which might have implications for human pathophysiology.
Usefulness of Pravastatin in Primary Prevention of Cardiovascular Events in Women: Analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA Study)

Background— It is well known that statins reduce the risk of cardiovascular disease. However, the effect of statins in women for the primary prevention of cardiovascular disease has not been determined. We conducted an exploratory analysis of the effect of diet plus pravastatin therapy on the primary prevention of cardiovascular events in women with data from a large-scale primary prevention trial with pravastatin. Methods and Results— Patients with hypercholesterolemia (5.7 to 7.0 mmol/L) and no history of coronary heart disease or stroke were randomized to diet or diet plus pravastatin 10 to 20 mg/d and followed up for ≥5 years. We investigated the effect of diet plus pravastatin treatment on cardiovascular events in 5356 women during the 5-year follow-up. The incidence of cardiovascular events in the women was 2 to 3 times lower than that in men. The occurrence of cardiovascular events was 26% to 37% lower in the diet plus pravastatin treatment group than in the diet alone group. Although these differences did not reach statistical significance, the overall risk reductions were similar to those in men. Notably, women ≥60 years of age treated with diet plus pravastatin had markedly higher risk reductions for coronary heart disease (45%), coronary heart disease plus cerebral infarction (50%), and stroke (64%) than did women treated with diet alone. Conclusions— Treatment with pravastatin in women with elevated cholesterol but no history of cardiovascular disease provides a benefit similar to that seen in men, and this benefit is more marked in older women. This treatment should be considered routinely for primary cardiovascular protection in women with elevated cholesterol levels.
Aryans reading Adorno: cyber-culture and twenty-firstcentury racism

This article examines the ways in which digital technology is being used in contemporary forms of racist culture within white nationalist movements. It argues that new types of racist culture are made possible in cyberspace. This both challenges popular conceptions of what 'The Racist' is supposed to look like and points the ways in which technological innovation is reinvigorating anti-Semitism and racisms that work in and through the boundaries of nation-states. It is argued that it is possible to situate racism and white nationalism at the centre of the so-called postmodern condition.
Interprovincial Return Migration in China: Individual and Contextual Determinants in Sichuan Province in the 1990S

China's massive volume of and dramatic increase in migration have stimulated increasing research in this area. However, researchers have not paid sufficient attention to return migration until recently when the issue of migrant labor shortage in Southern China has been linked to return migration back to the rural areas. Taking advantage of information contained in the 1995 China 1% Population Sample Survey and the 2000 China Census, this paper provides a systematic analysis of interprovincial return migration to Sichuan province, one of the most important migrant-sending provinces in China. We focus on return migrant selectivity, the impact of local labor-market conditions and migration networks on return migration, and nonfarm work participation among return migrants. Return migration in the late 1990s shows positive selection on education and return migrants are more likely to engage in nonfarm work. The pattern for the early 1990s is just the opposite of what is observed in the late 1990s. Our multilevel models show that labor-market conditions as well as migration networks in destination areas play important roles in the return migration process. Policy implications of this trend of return migration are discussed.
The Products of the Drosophila stoned Locus Interact with Synaptic Vesicles via Synaptotagmin

The stoned locus of Drosophila melanogaster encodes two novel proteins, stonedA (STNA) and stonedB (STNB), both of which are expressed in the nervous system. Flies with defects at the stoned locus have abnormal behavior and altered synaptic transmission. Genetic interactions, in particular with the shibire (dynamin) mutation, indicated a presynaptic function for stoned and suggested an involvement in vesicle cycling. Immunological studies revealed colocalization of the stoned proteins at the neuromuscular junction with the integral synaptic vesicle protein synaptotagmin (SYT). We show here that stoned interacts genetically with synaptotagmin to produce a lethal phenotype. The STNB protein is found by co-immunoprecipitation to be associated with synaptic vesicles, and glutathione S-transferase pull-downs demonstrate an in vitro interaction between the μ2-homology domain of STNB and the C2B domain of the SYTI isoform. The STNA protein is also found in association with vesicles, and it too exhibits an in vitro association with SYTI. However, we find that the bulk of STNA is in a nonmembranous fraction. By using the shibire mutant to block endocytosis, STNB is shown to be present on some synaptic vesicles before exocytosis. However, STNB is not associated with all synaptic vesicles. We hypothesize that STNB specifies a subset of synaptic vesicles with a role in the synaptic vesicle cycle that is yet to be determined.
Experiments in Mobile Social Networking

Number: CR-PRL-2008-02-0003Date: February 7th 2008Abstract: In this report we consider a mobile ad hoc network settingwhere users of Bluetooth enabled devices meet and communicate op-portunistically as when random people meet in a cafe, or researchersmeet at a conference. Ad hoc opportunistic contacts are built on thebasis of pre-deﬁned relationships in online social networks. Our ap-proach distinguishes itself from previous work in the area by threecharacteristics: the removal of a need for a central server to conductexchanges, the focus on the transitive closure of relationships, andthe use of existing social networks as a reference point for under-standing whether an exchange is desirable. We design MobiClique,a social interaction communication software package that we imple-ment on smartphones. We develop three applications: ad hoc socialconnections, epidemic newsgroups and asynchronous messaging. Wedescribe our experience with 28 users at a networking conference. Wediscover that despite the usual experimental hazards, MobiClique wassuccessful at building a local social network and delivering more than300 user generated messages over 3 days through multi-hop epidemiccommunication.
On the diphthong/hiatus contrast in Spanish: some experimental results

Some Spanish dialects have a lexical contrast between sequences in hiatus and diphthongs. Thus, whereas, for instance, dueto 'duet' admits a trisyllabic pronunciation with the sequence ue realized in hiatus [du.e. to], the word duelo 'sorrow' can only be pronounced as bisyllabic [dwe.lo]. Similarly, [pi.e] I chirped' contrasts with [pje] foot' in this manner. The interest of this phenomenon lies in the fact that it represents a clear case of phonological contrasts between hiatus and diphthong or, in other terms, between high vowels and glides. What remains largely unknown is the dialectal extension of this contrast and how consistently specific items are classified as belonging to either the hiatus or the diphthong class within a given dialect or across dialects. In this paper we report on an experiment designed to test the consistency of the distinction in Madrid Spanish, as a first step in the crossdialectal investigation of the phenomenon. We measured the duration of the sequence ia in a group of test words inserted in a uniform carrier sentence. The results show that for all six speakers tested, the hypothesized hiatus and diphthong classes present different durational distributions, the sequence ia tending to be longer in hiatus-class words, although there is a certain amount of overlap between the groups and some variation.
The Problem of Legitimacy in the Experience of Work-Related Back Injury

In an ethnographic study of work-related back injury, the problem of legitimacy was a central feature of workers' experiences. Injured workers encountered suspicion in their workplaces regarding the validity of their claims to back injury and their need for compensable time off work. The experience was associated, in most instances, with damaged relations at work and jeopardized job security. Underpinning workers' experience were the nature of medical knowledge on back injuries and the design of the workers' compensation system. The relationship of this analysis to the issues of malingering and moral evaluation in the workplace is examined, as is the possibility that the problem of legitimacy contributes to chronic disability from work-related back injury.