Miracle-dz/UniFAR-FTUs huggingface dataset:
Real-time kinematic positioning with NASA ’ s Internet-based Global Differential GPS ( IGDG )

Keywords: global DGPS, kinematic positioning, real-time dm-accuracy The Global Differential GPS (GDGPS) system developed by JPL aims at seamless global real-time positioning at the dm accuracy level for dual-frequency receivers either static or mobile, anywhere and at any time. The GDGPS system relies on GPS data transmitted in real-time to a central processing center at JPL from a global network of permanently operating GPS dual-frequency receivers. At the processing center, the Internet-based Global Differential GPS (IGDG) system, the heart of JPL's GDGPS, generates and disseminates over the open Internet special 1-second global differential corrections (IGDG corrections) to the GPS broadcast ephemerides. The IGDG corrections enhance the accuracy of GPS broadcast orbits and clocks down to the dm level and are the key-factor in high-precise real-time positioning of a stand-alone receiver. An independent experimental verification of the dm positional accuracy of IGDG system was carried out, by means of both a static and a kinematic test in the Netherlands. In the static test, the means of the position coordinates, taken over individual days of data, agree with the known reference at the 1-2 cm level confirming that the IGDG position solutions are free of systematic biases. The standard deviation of individual real-time position solutions turned out to be 10 cm for the horizontal components and 20 cm for the vertical component. In the kinematic test, carried out with a small boat, the means of coordinate differences with an accurate ground-truth trajectory, are at 1-2 dm level over the almost 3 hour period; the standard deviations of individual positions were similar to values found in the static test, 10 cm for the horizontal components, and 20 cm for the vertical component. More than 99% of the IGDG-corrections were received in the field with the nominal interval of 1 second, using a GPRS cellular phone. The latency of the corrections was generally 7 to 8 seconds.
Criterion validity of the French version of Patient Health Questionnaire (PHQ) in a hospital department of internal medicine.

OBJECTIVES Depressive disorders are overrepresented among the patients admitted to non-psychiatric units in general hospitals. However, the majority of depressed patients fail to be identified within this care setting. Since a self-administered questionnaire (Patient Health Questionnaire, PHQ-9) has given encouraging results in English and Spanish, new research should test its criterion validity in a French-speaking environment. DESIGN The study included 292 patients admitted to the internal medicine units of the University Hospitals of Geneva. Each patient filled the PHQ-9; 212 patients also underwent a blinded DSM-IV diagnostic assessment by a psychiatrist. METHODS In order to assess the validity of PHQ-9 against the gold standard of the psychiatrist's DSM-IV diagnosis, we calculated overall accuracy, sensitivity, specificity, positive predictive value and Cohen kappa coefficients. We also studied the relationship between the PHQ-9 diagnostic and the severity of depression. Finally, analysis focused on the presence of a diagnosis of depression. RESULTS Within the framework of the study, PHQ-9 showed an acceptable level of specificity. However, its sensitivity in detecting major depression was low (about 50% of false-negative results). As regards the overall presence of depressive disorders, this instrument performed hardly any better (35% of false negatives). Other characteristics of the population under investigation may have affected the data. CONCLUSIONS The French version of PHQ-9 demonstrated low sensitivity as compared with psychiatrist-established diagnosis of DSM-IV A criterion and major depressive episode.
Attitude Estimation and Control Using Linearlike Complementary Filters: Theory and Experiment

This brief proposes new algorithms for attitude estimation and control, based on fused inertial vector measurements using a linear complementary filters principle. First, n-order direct and passive complementary filters combined with a TRIaxial Attitude Determination algorithm are proposed to give the attitude estimation solutions. These solutions that are efficient with respect to noise include the gyro-bias estimation. Thereafter, the same principle of data fusion is used to address the problem of attitude tracking based on the inertial vector measurements. Thus, instead of using noisy raw measurements in the control law, a new solution of control that includes a linearlike complementary filter to deal with the noise is proposed. The stability analysis of the tracking error dynamics based on the LaSalle's invariance theorem proved that almost all trajectories converge asymptotically to the desired equilibrium. Simulations and experimental results, obtained with DIY Quad equipped with the APM2.6 autopilot, show the effectiveness and the performance of the proposed solutions.
Money wage rigidity, monopoly power and hysteresis

The literature that addresses the effects on the level of aggregate demand of changes in the degree of monopoly typically assumes away the existence of an “inflation barrier” and an inflationtargeting central bank. The presence of these two institutional factors entails that any aggregate demand change brought about by changes in the functional distribution of income will tend to be offset by changes in real interest rates. We postulate a simple macroeconomic model for a closed economy with a government sector and hypothesize that a change in the average mark up affects the inflation rate, the “inflation-barrier” and aggregate demand. The model allows for the analysis of the effects on the employment rate of demand and supply shocks when the economy exhibits asymmetric inflation dynamics (AID) and hysteresis effects. Among other results we find that, if the economy exhibits AID and hysteresis, the effect on the employment rate of a change in the mark up is likely to be either ineffectual or counterproductive even if the associated demand shock is expansionary. We also show that an inadequate functional distribution of income may lead to the occurrence of an aggregate demand deficiency problem.
Mycobacterium tuberculosis infection of bilateral cervical lymph nodes after renal transplantation

We report the case of a 52‐year‐old man who underwent a renal transplantation and subsequently developed extrapulmonary tuberculosis. The immunosuppressive agent was intravenously administered continuously together with antituberculosis drugs. The tuberculosis improved and renal function has been well preserved for more than 3 years post transplantation.
Optimization of extraction of chitosan and carotenoids from shrimp waste

This study describes pigments and chitosan extraction from shrimp wastes under different methods. Chitosan were extracted and measured from shrimp waste according to the conventional method. But in step of deproteinization, three process acid, alkaline, and enzyme extraction was used. Carotenoids are also evaluated as by product. The degree of deacetylation and the moisture percent was also determined. The total chitosan level for acid, enzyme, and alkaline methods were 1.95±0.014, 1.33±0.014, and 0.183±0.007 mg/ml and total carotenoids 44.77±0.2, 184.58±0.447, and 85.17±0.9 respectively. These results demonstrated that good yields can be obtained enzymatic treatment. Subject to economic advantages, enzymatic can replace the other methods.
Activation of EphA Receptors Mediates the Recruitment of the Adaptor Protein Slap, Contributing to the Downregulation of N-Methyl-d-Aspartate Receptors

ABSTRACT Regulation of the activity of N-methyl-d-aspartate receptors (NMDARs) at glutamatergic synapses is essential for certain forms of synaptic plasticity underlying learning and memory and is also associated with neurotoxicity and neurodegenerative diseases. In this report, we investigate the role of Src-like adaptor protein (Slap) in NMDA receptor signaling. We present data showing that in dissociated neuronal cultures, activation of ephrin (Eph) receptors by chimeric preclustered eph-Fc ligands leads to recruitment of Slap and NMDA receptors at the sites of Eph receptor activation. Interestingly, our data suggest that prolonged activation of EphA receptors is as efficient in recruiting Slap and NMDA receptors as prolonged activation of EphB receptors. Using established heterologous systems, we examined whether Slap is an integral part of NMDA receptor signaling. Our results showed that Slap does not alter baseline activity of NMDA receptors and does not affect Src-dependent potentiation of NMDA receptor currents in Xenopus oocytes. We also demonstrate that Slap reduces excitotoxic cell death triggered by activation of NMDARs in HEK293 cells. Finally, we present evidence showing reduced levels of NMDA receptors in the presence of Slap occurring in an activity-dependent manner, suggesting that Slap is part of a mechanism that homeostatically modulates the levels of NMDA receptors.
Evaluation in öffentlichen Dienstleistungsorganisationen : eine empirische Untersuchung zur Entstehung des Publikumsurteils im Musiktheater

Within the framework of the comprehensive reforms known as ‚New Public Management’, the issue of measuring performance quality in public opera companies comes to the fore. Since quality in opera companies is generally considered difficult to measure (Heinze, 1994; Lipp, 1994; Hoegl, 1995; Allmann, 1997) and quality concepts both for for-profit and nonprofit companies are not applicable (Boerner, 2002), there exists no valid and reliable scientific tool that is able to grasp the performance quality of an opera company. Therefore the aim of this paper is to close this gap by conducting research in the evaluation of opera performances. By using a modified version of the questionnaire that is based on Boerner’s componential framework of performance quality in the opera and was developed by Moser (2005) und Renz (2006) to understand the perception of performance quality in the opera this study examines two objects: First of all it investigates the content, the structure and the agreement in judgments on performance quality in the opera. The second part of this work focuses on the audience’s judgment on the whole evening in the opera as the analysis of the literature suggests that there are other criteria besides the performance quality used by the audience. Members of the audience of a performance of “Die Zauberflote” by Wolfgang Amadeus Mozart were asked to answer the questionnaire after attending a performance in the opera house of Dessau (n = 120). In terms of the performance’s content, factor analysis yields that the audience separates between the fit between the musical dimension and the staging dimension, the fit within the musical dimension, the fit within the staging dimension, the orchestra, the choir, the soloists and the staging/scenery. A following path analysis confirms a hierarchical structure of the perception of performance quality as assumed by the componential framework of Boerner (2002). Furthermore, the fit between the musical dimension and the staging dimension is shown to be the most important component with regard to the weight within the audience’s judgment concerning the performance quality. The agreement about the assessment within both the sample of non-experts and of experts is high. While identifying the determinants of the audience’s judgment on the whole evening in the opera house, path analysis yields the affective response to the performance as a better predictor of enjoyment than the perceived quality of the performance. Additional variables (such as the complexity of the production or the audience’s satisfaction with the auditorium) were shown to make virtually no contribution to the audience’s overall enjoyment of the evening in the opera. Again, the agreement within the sample of both the non-experts and the experts about the assessment of the different aspects is generally high.
TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells1

In the past, ZAP70 was considered a T cell-specific kinase, and its aberrant expression in B-CLL cells was interpreted as a sign of malignant transformation and dedifferentiation. It was only recently that ZAP70 was detected in normal human B cells. In this study, we show that TLR9-activated B cells resemble B-cell chronic lymphocytic leukemia cells with regard to CD5, CD23, CD25, and heat shock protein 90 expression. Furthermore, stimulatory CpG and GpC DNA oligonucleotides target CD27+IgM+ and CD27−IgM+ B cells (but not IgM− B cells) and enhance ZAP70 expression predominantly in the IgM+CD27+ B cell subset. ZAP70 is induced via activation of TLR-7 or -9 in a MyD88-dependent manner, depends on protein kinase B (PKB)/mammalian target of rapamycin signaling and is rapamycin sensitive. Furthermore, ZAP70 expression levels correlate with induction of cyclin A2, prolonged B cell proliferation, and sustained induction of PKB. These events are not observed upon CD40 ligation. However, this deficit can be overcome by the expression of constitutively active PKB, given that CD40 ligation of PKB-transgenic B cells induces B cell proliferation and ZAP70 expression. These results highlight a major difference between CD40- and TLR-7/9-mediated B cell activation and suggest that ZAP70 expression levels in B cells give an estimate of the proliferative potential and the associated PKB availability.
Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.

BACKGROUND Protein expression profiling for differences indicative of early cancer has promise for improving diagnostics. This report describes the first stage of a National Cancer Institute/Early Detection Research Network-sponsored multiinstitutional evaluation and validation of this approach for detection of prostate cancer. METHODS Two sequential experimental phases were conducted to establish interlaboratory calibration and standardization of the surface-enhanced laser desorption (SELDI) instrumental and assay platform output. We first established whether the output from multiple calibrated Protein Biosystem II SELDI-ionization time-of-flight mass spectrometry (TOF-MS) instruments demonstrated acceptable interlaboratory reproducibility. This was determined by measuring mass accuracy, resolution, signal-to-noise ratio, and normalized intensity of three m/z "peaks" present in a standard pooled serum sample. We next evaluated the ability of the calibrated and standardized instrumentation to accurately differentiate between selected cases of prostate cancer and control by use of an algorithm developed from data derived from a single site 2 years earlier. RESULTS When the described standard operating procedures were established at all laboratory sites, the across-laboratory measurements revealed a CV for mass accuracy of 0.1%, signal-to-noise ratio of approximately 40%, and normalized intensity of 15-36% for the three pooled serum peaks. This was comparable to the intralaboratory measurements of the same peaks. The instrument systems were then challenged with sera from a selected group of 14 cases and 14 controls. The classification agreement between each site and the established decision algorithm were examined by use of both raw peak intensity boosting and ranked peak intensity boosting. All six sites achieved perfect blinded classification for all samples when boosted alignment of raw intensities was used. Four of six sites achieved perfect blinded classification with ranked intensities, with one site passing the criteria of 26 of 28 correct and one site failing with 19 of 28 correct. CONCLUSIONS These results demonstrate that "between-laboratory" reproducibility of SELDI-TOF-MS serum profiling approaches that of "within-laboratory" reproducibility as determined by measuring discrete m/z peaks over time and across laboratories.
Modeling the Temperature Dependence of Hysteresis Based on Jiles–Atherton Theory

A temperature-dependent model is necessary in order to understand the behavior of magnetization processes in ferromagnetic materials at different temperatures. In the present study, a physical model based on Jiles-Atherton (JA) theory was developed to study the effects of temperature on magnetic hysteresis. The thermal effects were incorporated through temperature-dependent hysteresis parameters of the existing model, adding critical exponent and Curie temperature as additional parameters. The temperature-dependent JA model was validated against measurements made on substituted cobalt ferrite material, and the results were in good agreement.
ACRIM‐gap and TSI trend issue resolved using a surface magnetic flux TSI proxy model

The ACRIM‐gap (1989.5–1991.75) continuity dilemma for satellite TSI observations is resolved by bridging the satellite TSI monitoring gap between ACRIM1 and ACRIM2 results with TSI derived from Krivova et al.'s (2007) proxy model based on variations of the surface distribution of solar magnetic flux. ‘Mixed’ versions of ACRIM and PMOD TSI composites are constructed with their composites' original values except for the ACRIM gap, where Krivova modeled TSI is used to connect ACRIM1 and ACRIM2 results. Both ‘mixed’ composites demonstrate a significant TSI increase of 0.033 %/decade between the solar activity minima of 1986 and 1996, comparable to the 0.037 % found in the ACRIM composite. The finding supports the contention of Willson (1997) that the ERBS/ERBE results are flawed by uncorrected degradation during the ACRIM gap and refutes the Nimbus7/ERB ACRIM gap adjustment Fröhlich and Lean (1998) employed in constructing the PMOD.
Impact différentiel de l'œstradiol sur la fonction mnésique selon l’âge et le type de mémoire

Estradiol (E2) is a potential therapeutic target against age-related memory decline. Indeed, E2 promotes synaptic plasticity processes impaired in aging and thought to underlie mnemonic retention. However, the literature reveals a much more complex picture, leading to reconsider the relationships between E2 and memory. The aim of my PhD work was to improve our understanding of the mnemonic effects of a chronic supplementation of E2 in young and aged male mice. In aged animals, E2 supplementation reduces hippocampal-dependent memory deficits called declarative memory, by improving the capacity to link temporally distant event which depends on CA1 functionality. However, the supplementation had no effect on the severe deficits of short-term/working memory which solicits not only retention but also the organization of learned information and forgetting to avoid interference. In young animals, E2 can induce deleterious effects on regular mnemonic function. Indeed, the prolongation of mnemonic retention can paradoxically imapir working memory by aggravating interference effects. This effect was associated with a functional alteration centered on dentate gyrus. Our behavioral results show that E2 prolongs mnemonic retention but, in accordance with our hypotheses, but depending on the age of the subject and the type of memory involved in the task, this promnesic effect does not necessarily induce an improved performance.Our work confirms the therapeutic interest of E2 in the context of mnemonic aging and allows pinpointing its limits. This work also invites to carefully consider the consequences of a growing exposition to environmental estrogenic compounds on public health.
Decoding Trajectories from Posterior Parietal Cortex Ensembles

High-level cognitive signals in the posterior parietal cortex (PPC) have previously been used to decode the intended endpoint of a reach, providing the first evidence that PPC can be used for direct control of a neural prosthesis (Musallam et al., 2004). Here we expand on this work by showing that PPC neural activity can be harnessed to estimate not only the endpoint but also to continuously control the trajectory of an end effector. Specifically, we trained two monkeys to use a joystick to guide a cursor on a computer screen to peripheral target locations while maintaining central ocular fixation. We found that we could accurately reconstruct the trajectory of the cursor using a relatively small ensemble of simultaneously recorded PPC neurons. Using a goal-based Kalman filter that incorporates target information into the state-space, we showed that the decoded estimate of cursor position could be significantly improved. Finally, we tested whether we could decode trajectories during closed-loop brain control sessions, in which the real-time position of the cursor was determined solely by a monkey's neural activity in PPC. The monkey learned to perform brain control trajectories at 80% success rate (for 8 targets) after just 4–5 sessions. This improvement in behavioral performance was accompanied by a corresponding enhancement in neural tuning properties (i.e., increased tuning depth and coverage of encoding parameter space) as well as an increase in off-line decoding performance of the PPC ensemble.
Long-term effects of pediatric intensive care unit hospitalization on families with young children.

OBJECTIVE The purpose of this study was to prospectively examine the long-term effects of the pediatric intensive care unit experience on parents and on family adaptation. DESIGN A three-group prospective, comparison, convenience sample was used in this study. SETTING The study took place in a midwestern university-affiliated tertiary pediatric medical center. SUBJECTS Three groups of parents (parents with children in the pediatric intensive care unit, parents with children in a general care unit, and parents with nonhospitalized ill children) were studied. The children were ages 5 years or younger. OUTCOME MEASURES Indicators of family adaptation included parental stress, stress symptoms, family functioning, and life events. RESULTS The mothers' stress symptoms in all groups were more prevalent than a normative sample, and they perceived their families as dysfunctional after discharge from the hospital. Slope analysis was used to examine the patterns of stress symptoms and family functioning and indicated little directional change over time for the mothers. CONCLUSION Despite the smaller than expected sample sizes over time, results suggest that parents are still having stress-related symptoms and difficulties with family functioning as long as 6 months after a child's illness event.
Time to gain trust and change—Experiences of attachment and mindfulness-based cognitive therapy among patients with chronic pain and psychiatric co-morbidity

The treatment of patients with chronic pain disorders is complex. In the rehabilitation of these patients, coping with chronic pain is seen as important. The aim of this study was to explore the meaning of attachment and mindfulness-based cognitive therapy (CT) among patients with chronic pain and psychiatric co-morbidity. A phenomenological approach within a lifeworld perspective was used. In total, 10 patients were interviewed after completion of 7- to 13-month therapy. The findings reveal that the therapy and the process of interaction with the therapist were meaningful for the patients’ well-being and for a better management of pain. During the therapy, the patients were able to initiate a movement of change. Thus, CT with focus on attachment and mindfulness seems to be of value for these patients. The therapy used in this study was adjusted to the patients’ special needs, and a trained psychotherapist with a special knowledge of patients with chronic pain might be required.