Miracle-dz/UniFAR-FTUs huggingface dataset:
PENINGKATAN KUALITAS HIDUP LANJUT USIA (LANSIA) DI KOTA DEPOK DENGAN LATIHAN KESEIMBANGAN

Kualitas hidup lansia dipengaruhi berbagai faktor seperti kesehatan fisik, kesehatan psikologis, hubungan sosial dan lingkungan. Penelitian ini bertujuan mengetahui pengaruh latihan keseimbangan terhadap kualitas hidup lansia di Kota Depok. Penelitian quasi experiment ini dilakukan pada dua kelompok; 30 lansia sebagai kelompok kontrol dan 30 lansia sebagai kelompok perlakuan. Teknik pengambilan sampel yang digunakan adalah multistage random sampling. Hasil penelitian menunjukkan bahwa latihan keseimbangan berpengaruh signifikan, meningkatkan kualitas hidup lansia (p<0,001). Hal ini disebabkan karena latihan keseimbangan dapat meningkatkan kesehatan fisik, kesehatan psikologis, hubungan sosial dan lingkungan. Latihan keseimbangan lansia dapat digunakan sebagai salah satu upaya untuk meningkatkan kualitas hidup pada lansia di komunitas. Penelitian selanjutnya dapat melakukan penelitian pada kelompok usia yang berbeda untuk mengetahui keefektifan latihan keseimbangan lansia. Kata Kunci: lansia, latihan keseimbangan, kualitas hidup Abstract Quality Improvement of Elderly Life in Depok City with Balance Exercise. The quality of life (QOL) of the older adult is affected by various factors such as physical health, psychological health, social relationships and environment. This study aimed to investigate the effect of balance exercise on quality of life among older adults. This quasi-experimental design included two groups; 30 subjects as intervention groups and 30 subjects as control groups. The sample was taken by multistage random sampling. There were significant improvements in quality of life among older adults (p<0,001). Balance exercise can improve physical health, psychological health, social relationships, and environment. Balance exercise can be utilized as one of the preventive efforts to increase the quality of life among older adults in the community. Further research may consider a variety of age to know the effectiveness of balance exercise. Keywords: balance exercise, older adult, quality of life
A First Step towards Privacy Leakage Diagnosis and Protection

In this paper, we present a first step for designing a privacy leakage diagnosis and protection system using two privacy definitions and a new definition, and then evaluate a prototype program. The diagnosis is based on major notions of privacy: k-anonymity and (c, l)-diversity. Furthermore, the diagnosis include another method that analyze sensitivity of each attribute values. The prototype program realizes a computation time of less than 1 ms for the diagnosis and updating of data. Thus, it provides a privacy-leakage level within a feasible computation time.
The Dividual Self: Ethno-Psychology, Idioms of Distress and Explanatory Models of Mental Illness in Karachi, Pakistan

The Dividual Self: Ethno-Psychology, Idioms of Distress and Explanatory Models of Mental Illness in Karachi, Pakistan Taha Sabri Chair of the Supervisory Committee: Deepa Rao Department of Public Health Research on cultural manifestations of distress, by examining ethno-psychology, idioms of distress and explanatory models of mental illness in indigenous populations, is essential to develop culturally sensitive mental health screening tools and interventions. This exploratory study used qualitative methods to understand the cultural manifestations of distress in a population of mental health practitioners, patients and laypeople (N=30) in Karachi, Pakistan. We used a phenomenological approach to conduct 30 in-depth interviews followed by thematic analysis. The ethno-psychology revealed a sense of self that is ‘dividual’; composed of many parts (physical, mental, emotional, social, and spiritual) and influenced by the external environment. Idioms of distress and explanatory models of mental illness revolved around these parts of the self. Idioms of distress pertaining to the ‘heart’ and ‘mind-brain’ constructs were observed, the most salient of which was tension. The most common explanatory models were those attributing mental illness to adverse social experiences. Idioms of distress and explanatory models also showed somatization, spiritualization and socialization of distress, as opposed to the psychological manifestation prominent in Western cultures. Significant differences were observed in the use of idioms and
Evaluating the Persona Effect of an Interface Agent in an Intelligent Tutoring System

This paper describes the evaluation of the persona effect of a speech-driven anthropomorphic agent that has been embodied in the interface of an Intelligent Tutoring System (ITS). This agent is responsible for guiding the student in the environment and communicating the system’s feedback messages. The agent was evaluated during an experiment in terms of the effect that it could have on students’ learning, behaviour and experience. The participants in the experiment were divided into two groups: half of them worked with a version of the ITS which embodied the agent and the rest worked with an agent-less version. The results from this study confirm the hypothesis that a pedagogical agent incorporated in an ITS can enhance students’ learning experience. On the other hand, the hypothesis that the presence of the agent improves short-term learning effects was rejected based on our data.
Design of a compact RF energy harvester for wireless sensor networks

We present a method for powering electronic devices from ambient Radio Frequency (RF) signals. Our proposed design of RF energy harvester is made of a compact ferrite rod antenna together with the electronics necessary for converting the received signal into a form that can directly replace batteries. We show that our device can, in principal, power a wireless sensor node from ambient medium wave transmissions so long as the node is within 120 km of a 150kW transmitter.
Identification of Major Epitopes of Mycobacterium tuberculosis AG85B That Are Recognized by HLA-A*0201-Restricted CD8+ T Cells in HLA-Transgenic Mice and Humans1

CD8+ T cells are thought to play an important role in protective immunity to tuberculosis. Although several nonprotein ligands have been identified for CD1-restricted CD8+ CTLs, epitopes for classical MHC class I-restricted CD8+ T cells, which most likely represent a majority among CD8+ T cells, have remained ill defined. HLA-A*0201 is one of the most prevalent class I alleles, with a frequency of over 30% in most populations. HLA-A2/Kb transgenic mice were shown to provide a powerful model for studying induction of HLA-A*0201-restricted immune responses in vivo. The Ag85 complex, a major component of secreted Mycobacterium tuberculosis proteins, induces strong CD4+ T cell responses in M. tuberculosis-infected individuals, and protection against tuberculosis in Ag85-DNA-immunized animals. In this study, we demonstrate the presence of HLA class I-restricted, CD8+ T cells against Ag85B of M. tuberculosis in HLA-A2/Kb transgenic mice and HLA-A*0201+ humans. Moreover, two immunodominant Ag85 peptide epitopes for HLA-A*0201-restricted, M. tuberculosis-reactive CD8+ CTLs were identified. These CD8+ T cells produced IFN-γ and TNF-α and recognized Ag-pulsed or bacillus Calmette-Guérin-infected, HLA-A*0201-positive, but not HLA-A*0201-negative or uninfected human macrophages. This CTL-mediated killing was blocked by anti-CD8 or anti-HLA class I mAb. Using fluorescent peptide/HLA-A*0201 tetramers, Ag85-specific CD8+ T cells could be visualized in bacillus Calmette-Guérin-responsive, HLA-A*0201+ individuals. Collectively, our results demonstrate the presence of HLA class I-restricted CD8+ CTL against a major Ag of M. tuberculosis and identify Ag85B epitopes that are strongly recognized by HLA-A*0201-restricted CD8+ T cells in humans and mice. These epitopes thus represent potential subunit components for the design of vaccines against tuberculosis.
A simple nonlinear PID control for global finite-time regulation of robot manipulators without velocity measurements

A simple nonlinear proportional-integral-derivative (PID) controller is proposed for global finite-time regulation of robot manipulators without velocity measurements. A Lyapunov-based stability argument is employ to prove global finite-time stabilization. The proposed control algorithm does not involve the model parameters in the control law formulation and the control gains can be explicitly determined based on some well-known bounds extracted from the robot dynamics, and thus permits easy implementation. Simulations are included to demonstrate the expected properties of the proposed approach.
Mathematics Learned by Young Children in an Intervention Based on Learning Trajectories: A Large-Scale Cluster Randomized Trial

This study employed a cluster randomized trial design to evaluate the effectiveness of a research-based intervention for improving the mathematics education of very young children. This intervention includes the Building Blocks mathematics curriculum, which is structured in research-based learning trajectories, and congruous professional development emphasizing teaching for understanding via learning trajectories and technology. A total of 42 schools serving low-resource communities were randomly selected and randomly assigned to 3 treatment groups using a randomized block design involving 1,375 preschoolers in 106 classrooms. Teachers implemented the intervention with adequate fidelity. Pre- to posttest scores revealed that the children in the Building Blocks group learned more mathematics than the children in the control group (effect size, g = 0.72). Specific components of a measure of the quantity and quality of classroom mathematics environments and teaching partially mediated the treatment effect.
Th 17 Cell Related Cytokine Profiles in Narcolepsy and Other Types of Excessive Daytime Sleepiness

Background and Objective: Narcolepsy is a chronic neurological disorder caus ed by loss of hypocretin (Hcrt) neurons. Both genetic and environmental factors pla y an important role for the development of narcolep sy. The mechanism of Hcrt loss in narcolepsy is elusive; ho wever, an autoimmune mediated destruction of Hcrt n eurons is suspected. The purpose of this study was to assess Th17 related cytokines: interleukin-6 (IL-6), IL-17 , IL-23, and transforming growth factor beta (TGFβ) in the pathophysiology of narcolepsy and other ty pes of excessive daytime sleepiness (EDS). Materials and Methods: A total of 15 narcoleptic patients, 35 other patien ts with EDS and 48 age and sex matched healthy subjects were enrolled in this case-control study. Serum IL-6, IL-17, IL-23, and TGFβ levels were measured using sandwich enzyme-linked immunosorbent assay. Results: There was no significant difference in IL-6 (P = 0. 0618) and IL-23 (P = 0.7717) level among participan ts with narcolepsy, other patients with EDS and contro ls, whereas TGFβ was significantly decreased in the ones with narcolepsy and other EDS compared to healthy contro ls (P = 0.0039). Conclusion: Decreased level of TGFβ in narcolepsy and other patients with EDS indicate s a clue for the presence of dysregulation of inflammatory cascades in these patients. This study sheds a new insight o n the pathophysiology of narcolepsy. © 2016 Tehran University of Medical Sciences. All r ights reserved.
Dynamic access class barring for M2M communications in LTE networks

When incorporating machine-to-machine (M2M) communications into Long Term Evolution (LTE) networks, one of the challenges is the traffic overload due to a large number of machine type communications (MTC) devices with bursty traffic. One approach to tackle this problem is to use the access class barring (ACB) mechanism to regulate the opportunity of MTC devices to transmit request packets. In this paper, we first present an analytical model to determine the expected total access delay of all the MTC devices. For the ideal case that the LTE base station (eNodeB) knows the number of backlogged users, we determine the optimal value of the ACB factor, which can best reduce the congestion and access delay. For the practical scenario, we propose a heuristic algorithm to adaptively change the ACB factor without the knowledge of the number of backlogged users. Results show that the proposed heuristic algorithm achieves near optimal performance in reducing access delay.
Brain and behavioral correlates of action semantic deficits in autism

Action-perception circuits containing neurons in the motor system have been proposed as the building blocks of higher cognition; accordingly, motor dysfunction should entail cognitive deficits. Autism spectrum conditions (ASC) are marked by motor impairments but the implications of such motor dysfunction for higher cognition remain unclear. We here used word reading and semantic judgment tasks to investigate action-related motor cognition and its corresponding fMRI brain activation in high-functioning adults with ASC. These participants exhibited hypoactivity of motor cortex in language processing relative to typically developing controls. Crucially, we also found a deficit in semantic processing of action-related words, which, intriguingly, significantly correlated with this underactivation of motor cortex to these items. Furthermore, the word-induced hypoactivity in the motor system also predicted the severity of ASC as expressed by the number of autistic symptoms measured by the Autism-Spectrum Quotient (Baron-Cohen etal., 2001). These significant correlations between word-induced activation of the motor system and a newly discovered semantic deficit in a condition known to be characterized by motor impairments, along with the correlation of such activation with general autistic traits, confirm critical predictions of causal theories linking cognitive and semantic deficits in ASC, in part, to dysfunctional action-perception circuits and resultant reduction of motor system activation.
The role of endometrial and subendometrial blood flows measured by three-dimensional power Doppler ultrasound in the prediction of pregnancy during IVF treatment.

BACKGROUND A good blood supply towards the endometrium is usually considered to be an essential requirement for implantation. We aimed to evaluate the role of endometrial and subendometrial blood flows in the prediction of pregnancy during IVF treatment. METHODS Patients undergoing the first IVF cycle were recruited. A three-dimensional (3D) ultrasound examination with power Doppler was performed on the day of oocyte retrieval to determine endometrial thickness, endometrial pattern, pulsatility index (PI) and resistance index (RI) of uterine vessels, endometrial volume, vascularization index (VI), flow index (FI) and vascularization flow index (VFI) of endometrial and subendometrial regions. RESULTS Uterine RI, endometrial VI and VFI were significantly lower in the pregnant group than the non-pregnant group. There was a non-significant trend of higher implantation and pregnancy rates in patients with absent endometrial or subendometrial blood flow. The number of embryos replaced and endometrial VI were the only two predictive factors for pregnancy. Receiver operator characteristic curve analysis revealed that the area under the curve was approximately 0.5 for all ultrasound parameters for endometrial receptivity. CONCLUSION Endometrial and subendometrial blood flows measured by 3D power Doppler ultrasound were not good predictors of pregnancy if they were measured at one time-point during IVF treatment.
Unprimed, M1 and M2 Macrophages Differentially Interact with Porphyromonas gingivalis

Porphyromonas gingivalis is a keystone pathogen in the development of chronic periodontitis. Tissue macrophages are amongst the first immune cells to respond to bacteria and depending on the cytokine profile at the infection site, macrophages are primed to react to infection in different ways. Priming of naive macrophages with IFN-γ produces a classical pro-inflammatory, antibacterial M1 macrophage after TLR ligation, whereas priming with IL-4 induces an anti-inflammatory tissue-repair M2 phenotype. Previous work has shown that M1 are preferentially generated in gingival tissue following infection with P. gingivalis. However, few studies have investigated the interactions of macrophage subsets with P. gingivalis cells. The aim of this study was to determine the ability of naive, M1 and M2 macrophages to phagocytose P. gingivalis and investigate how this interaction affects both the bacterial cell and the macrophage. M1 and M2 macrophages were both found to have enhanced phagocytic capacity compared with that of naive macrophages, however only the naive and M1 macrophages were able to produce a respiratory burst in order to clear the bacteria from the phagosome. P. gingivalis was found to persist in naive and M2, but not M1 macrophages for 24 hours. Phagocytosis of P. gingivalis also induced high levels of TNF-α, IL-12 and iNOS in M1 macrophages, but not in naive or M2 macrophages. Furthermore, infection of macrophages with P. gingivalis at high bacteria to macrophage ratios, while inducing an inflammatory response, was also found to be deleterious to macrophage longevity, with high levels of apoptotic cell death found in macrophages after infection. The activation of M1 macrophages observed in this study may contribute to the initiation and maintenance of a pro-inflammatory state during chronic periodontitis.
Ranking for BioMinT : Investigating Performance , Local Search and Homonymy Recognition

In this paper we investigate several hypotheses concerning document relevance ranking for biological literature. More specifically, we focus on three topics: performance, risk of local searching, and homonymy recognition. Surprisingly, we find that a simple ranker based on the occurrence of a single word performs best. Adding this word as a new search term to each query yields even better results. The risk of local searching, i.e. retrieving documents by query followed by local indexing vs. maintaining a local repository and index of the full MEDLINE database, is found to be negligible – contrary to intuition, the latter approach even performs worse on some queries. The removal of automatically determined homonyms yields almost indistinguishable results to the original query, so it is not inconceivable that the problem of homonymy in biological literature has been overstated. Concluding, our work shows that simple rankers may be competitive to vastly more complex ensemble systems which include biological background knowledge and part-of-speech tagging which have been previously applied to task. The result reconfirms common wisdom within this research field.
Why Social Preferences Matter - the Impact of Non-Selfish Motives on Competition, Cooperation and Incentives

A substantial number of people exhibit social preferences, which means they are not solely motivated by material self-interest but also care positively or negatively for the material payoffs of relevant reference agents. We show empirically that economists fail to understand fundamental economic questions when they disregard social preferences, in particular, that without taking social preferences into account, it is not possible to understand adequately (i) effects of competition on market outcomes, (ii) laws governing cooperation and collective action, (iii) effects and the determinants of material incentives, (iv) which contracts and property rights arrangements are optimal, and (v) important forces shaping social norms and market failures. Economics may be called the dismal science because economists routinely make worst case assumptions regarding people’s motives. Economic reasoning is typically based on the self-interest hypothesis, ie, on the assumption that all people are exclusively motivated by their material self-interest. This assumption rules out any heterogeneity with respect to other-regarding, social, preferences. It also contrasts sharply with economists’ emphasis on the heterogeneity of people’s tastes with regard to consumption activities. Our models typically allow heterogeneous tastes with regard to apples and bananas, with regard to hazardous and safe jobs, etc., but in the important realm of social preferences mainstream economics adheres to the extreme self-interest assumption. The purpose of this paper is to show that economists fail to understand core questions in economics if they insist on the self-interest hypothesis and rule out heterogeneity in the realm of social preferences. This is so for two reasons. First, during the last decade experimental economists have gathered overwhelming evidence that systematically refutes the self-interest hypothesis and suggests that a substantial fraction of the people exhibit social preferences, in particular, preferences for reciprocal fairness. Second, there is also strong evidence indicating that the deviations from self-interest have a fundamental impact on core issues in economics.
Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal

Stem cell function declines with age largely due to the biochemical imbalances in their tissue niches, and this work demonstrates that aging imposes an elevation in transforming growth factor β (TGF-β) signaling in the neurogenic niche of the hippocampus, analogous to the previously demonstrated changes in the myogenic niche of skeletal muscle with age. Exploring the hypothesis that youthful calibration of key signaling pathways may enhance regeneration of multiple old tissues, we found that systemically attenuating TGF-β signaling with a single drug simultaneously enhanced neurogenesis and muscle regeneration in the same old mice, findings further substantiated via genetic perturbations. At the levels of cellular mechanism, our results establish that the age-specific increase in TGF-β1 in the stem cell niches of aged hippocampus involves microglia and that such an increase is pro-inflammatory both in brain and muscle, as assayed by the elevated expression of β2 microglobulin (B2M), a component of MHC class I molecules. These findings suggest that at high levels typical of aged tissues, TGF-β1 promotes inflammation instead of its canonical role in attenuating immune responses. In agreement with this conclusion, inhibition of TGF-β1 signaling normalized B2M to young levels in both studied tissues.
An asynchronous [(n - 1)/3]-resilient consensus protocol

A consensus protocol enables a system of <italic>n</italic> asynchronous processes, some of them malicious, to reach agreement. No assumptions are made on the behaviour of the processes and the message system; both are capable of colluding to prevent the correct processes from reaching decision. A protocol is <italic>t</italic>-resilient if in the presence of up to <italic>t</italic> malicious processes it reaches agreement with probability 1. In a recent paper, <italic>t</italic>-resilient consensus protocols were presented for <italic>t</italic><<italic>n</italic>/5. We improve this to <italic>t</italic><<italic>n</italic>/3, thus matching the lower bound on the number of correct processes necessary for consensus. The protocol restricts the behaviour of the malicious processes to that of merely fail-stop processes, which makes it interesting in other contexts.