Miracle-dz/UniFAR-FTUs huggingface dataset:
The nature of trust in brands: a psychosocial model

Purpose – The paper seeks to explore empirically the lived experience of trust in consumer brands and to develop a model focusing on functional and symbolic brands.Design/methodology/approach – The paper presents an exploratory, grounded theory approach and the study conducted in‐depth interviews.Findings – The findings reveal that when consumers are facing buying choices of functional brands that do not involve much risk and the price is low, familiarity is sufficient for their action. When risk and price levels increase, consumers seek a safe purchase choice regarding functional brands through confidence and dependability, while in the case of symbolic brands consumers have to trust the brand in order to make a purchase choice.Research limitations/implications – By exploring the concept of trust within the consumer domain and in particular in relation to functional and symbolic brands, this study offers insights into an area that has received noticeably limited research up to today. Furthermore the deve.
Denitrification in the banks of fluctuating rivers: The effects of river stage amplitude, sediment hydraulic conductivity and dispersivity, and ambient groundwater flow

Hyporheic exchange induced by periodic river fluctuations leads to important biogeochemical processes, particularly nitrogen cycling, in riparian zones (RZs) where chemically distinct surface water and groundwater mix. We developed a two‐dimensional coupled flow, reactive transport model to study the role of bank storage induced by river fluctuations on removing river‐borne nitrate. Sensitivity analyses were conducted to quantify the effects of river amplitude, sediment hydraulic conductivity and dispersivity, and ambient groundwater flow on nitrate removal rate. The simulations showed that nitrification occurred in the shallower zone adjacent to the bank where oxic river water and groundwater interacted while denitrification occurred deeper into the aquifer and in the riverbed sediments where oxygen was depleted. River fluctuations greatly increased the amount of nitrate being removed; the nitrate removal rate increased as river amplitude increased. Similarly, increasing hydraulic conductivity increased overall nitrate removal since it expanded the denitrifying zone but decreased efficiency. In contrast, increasing sediment dispersivity increased the removal efficiency of nitrate because it promoted mixing between electron acceptors and donors. The presence and direction of ambient groundwater flow had a significant impact on nitrate removal rate when compared to neutral conditions. A losing river showed a larger nitrate removal rate, whereas a gaining river showed a smaller nitrate removal rate. Our results demonstrated that daily river fluctuations created denitrification hot spots within the RZ that would not otherwise exist under naturally neutral or gaining conditions.
A literature review to explore the link between treatment satisfaction and adherence, compliance, and persistence

Purpose To explore the published evidence on the link between treatment satisfaction and patients’ compliance, adherence, and/or persistence. Methods Articles published from January 2005 to November 2010 assessing compliance, adherence, or persistence and treatment satisfaction were identified through literature searches in Medline, Embase, and PsycInfo. Abstracts were reviewed by two independent researchers who selected articles for inclusion. The main attributes of each study examining the link between satisfaction and adherence, compliance, or persistence were summarized. Results The database searches yielded 1278 references. Of the 281 abstracts that met the inclusion criteria, 20 articles were retained. In the articles, adherence and compliance were often used interchangeably and various methods were used to measure these concepts. All showed a positive association between treatment satisfaction and adherence, compliance, or persistence. Sixteen studies demonstrated a statistically significant link between satisfaction and compliance or persistence. Of these, ten demonstrated a significant link between satisfaction and compliance, two showed a significant link between satisfaction and persistence, and eight demonstrated a link between either a related aspect or a component of satisfaction (eg, treatment convenience) or adherence (eg, intention to persist). An equal number of studies aimed at explaining compliance or persistence according to treatment satisfaction (n = 8) and treatment satisfaction explained by compliance or persistence (n = 8). Four studies only reported correlation coefficients, with no hypothesis about the direction of the link. The methods used to evaluate the link were varied: two studies reported the link using descriptive statistics, such as percentages, and 18 used statistical tests, such as Spearman’s correlation or logistic regressions. Conclusion This review identified few studies that evaluate the statistical association between satisfaction and adherence, compliance, or persistence. The available data suggested that greater treatment satisfaction was associated with better compliance and improved persistence, and with lower regimen complexity or treatment burden.
Performance Analysis of CSMA , MACA and MACAW Protocols for VANETs

(such as routing, broadcasting, security and others) of VANET in the last decade covering both vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) scenarios. One specific area of VANET that still faces significant challenges is the design of reliable and robust media access control (MAC) protocols for V2V communications. Many algorithms of V2V MAC methods (including various VANET standards) have been proposed for VANETs over the last, few years that also focused on the benefits and limitations of the proposed MAC techniques as well as their ease of implementation in practice and future deployment. In this paper, we have made the performance analysis of Carrier sense multiple access (CSMA), Multiple Access with Collision Avoidance (MACA) and Multiple Access with Collision Avoidance for Wireless (MACAW) for VANET environment.
Comparison of data mining clustering algorithms

Data mining is an area of computer and information science with large perspective of knowledge discovery from large database or dataset. Various types of disciplines are available under data mining and clustering or the unsupervised learning in particular. Clustering is a division of data into similar groups; each similar group is called a cluster. Object in a cluster are similar or close to each other. Clustering algorithms can be implemented via number of different approaches. We conducted the comparison on WEKA (The Waikato Environment for Knowledge Analysis) that is open source. This paper shows that study and comparison between different clustering algorithms-partitioning method, hierarchical method and density based method. Here we have used parameter cluster instance, iterations, sum of squared errors, time taken, etc. for prediction of forest fire.
Effects of Induced Wheel Running on the Circadian Activity Rhythms of Syrian Hamsters: Entrainment and Phase Response Curve

The goal of this study was to provide an example of nonsocial and nonphotic entrainment in Syrian hamsters, together with a corresponding phase response curve (PRC). Fourteen male hamsters were given 2-hr bouts of induced activity (mostly wheel running) at 23.83-hr intervals in constant darkness (DD). The activity onsets of 10 hamsters entrained to this manipulation, with no anticipatory activity present. After entrainment, the rhythms re sumed free-running from a time 0.66-3.91 hr after the onset of the last bout of induced activity. Postentrainment free-running periods were shorter than pre-entrainment values. The PRC for 2-hr pulses of induced activity in DD revealed phase advances induced in some animals between circadian time (CT) 4 and CT 11 (approximately the last half of the hamsters' rest period), and delays between CT 23 and CT 3 and between CT 17 and CT 20. The CTs for phase advances are compatible with the phase angle differences observed between rhythm and zeitgeber at the end of entrainment. Many features of the results (not all animals entraining, PRC characteristics, lack of observable anticipation to the daily stimuli, phase relationship between zeitgeber and activity rhythms) are similar to those from a previous study on social entrainment in this species (Mrosovsky, 1988). These similarities reinforce the idea that in duced activity and social zeitgebers act on activity rhythms via a common mechanism.
CAR-modified anti-CD19 T cells for the treatment of B-cell malignancies: rules of the road

Introduction: Malignancies of the B lymphocyte or its precursor include B-cell non-Hodgkin lymphoma as well as chronic and acute lymphoid leukemias. These are among the most common hematologic malignancies and many patients with B-cell malignancies are incurable. Although most patients initially respond to first-line treatment, relapse is frequent and is associated with a poor prognosis. T cells that are genetically engineered to express chimeric antigen receptors (CARs) recognizing the B-cell-associated molecule CD19 have emerged as a potentially potent and exciting therapeutic modality in recent years. Areas covered: This review explores the current peer-reviewed publications in the field and a discussion of expert opinion. Expert opinion: Genetic engineering of T cells has become clinically feasible and appears to be safe. Here we provide an insight into the process of patient selection, engineered T-cell production, infusion procedure, expected toxicities and efficacy of this exciting approach as it is practiced in the treatment of B-cell malignancies. Anti-CD19-redirected T cells likely represent the vanguard of an exciting new approach to treating cancer.
Regulation of E2F1 Function by the Nuclear Corepressor KAP1*

KAP1 is a nuclear corepressor with conserved domains for RING finger, B boxes, leucine zipper α helical coiled-coil region, plant homeo domain finger, and bromo domain. The plant homeo domain finger and bromo domain of KAP1 cooperatively function as a transcription repression domain by recruiting the histone deacetylase complex NuRD and histone H3 lysine 9-specific methyltransferase SETDB1. Here we report that KAP1 binds the E2F1 transcription factor in a retinoblastoma protein (pRb)-independent fashion and inhibits E2F1 activity. KAP1 stimulates formation of E2F1-HDAC1 complex and inhibits E2F1 acetylation. Ectopic expression of KAP1 represses E2F1 transcription and apoptosis functions independent of pRb. Depletion of endogenous KAP1 in pRb-deficient Saos2 cells by RNA interference increases E2F1 acetylation level, stimulates E2F1 transcriptional activity, and sensitizes apoptosis response to DNA damage. Therefore, KAP1 contributes to the negative regulation of E2F1 and may serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of pRb.
Key Challenges to Ecological Modernization Theory

We raise four challenges to the claim of ecological modernization theory (EMT) that continued modernization is necessary for ecological sustainability. First, EMT needs to go beyond merely demonstrating that societies modify their institutions in reaction to environmental problems and show that such modifications lead to ecological improvements. Second, EMT must show that late stages of modernizing processes lead to the ecological transformation of production and consumption at relatively high frequency. Third, EMT must demonstrate that industries or firms that are reducing their direct impact on the environment are not contributing to the expansion of negative impacts by other industries or firms. Fourth, EMT must show not only that economies are becoming more resource efficient but also that the pace of increase in efficiency exceeds the pace of increase in overall production. In this article, we review the existing evidence and find that EMT has insufficiently addressed these four issues.
Effect on plasma lipids and lipoproteins of replacing partially hydrogenated fish oil with vegetable fat in margarine

We have compared the effects on lipoproteins and haemostatic variables of two hard margarines with similar functional properties, one traditional margarine containing partially hydrogenated fish oil (PHFO), and one experimental margarine based on vegetable oil (VO). Both were all-purpose cooking margarines with nearly identical functional properties. Trans fatty acids from PHFO in the traditional margarine were replaced mostly by saturated, monounsaturated and trans fatty acids of vegetable origin in the new formulation. Both test margarines contained approximately the same amount of cis polyunsaturated fatty acids. Sixteen female normolipidaemic students consumed each diet with the two test margarines for 14 d in random order (crossover design). The amount of fat was 31 % energy in the PHFO diet and 32 % energy in the VO diet. The test margarines provided approximately 26% energy in both diets. In the PHFO diet 7.8 % of the energy was derived from trans fatty acids and 9.2 % from saturated fatty acids (12:0, 14:0 and 16:0) while in the VO diet, 1.1 % energy was derived from trans fatty acids and 13.3% from saturated fatty acids (12:0, 14:0 and 16:0). The natural content of cholesterol in PHFO was deliberately not balanced by addition of cholesterol to the VO diet, thus the PHFO diet contained 215 mg and the VO diet 86 mg cholesterol per 8.5 MJ. LDL-cholesterol concentration was 19 % higher in subjects on the PHFO diet compared with the VO diet (P < 0.01). The ratio LDL-cholesterol:HDL-cholesterol was 12.6 % higher in subjects on the PHFO diet compared with the VO diet (P < 0.01). The level of apolipoprotein (apo)A-I was 6 % lower in subjects on the PHFO diet compared with the VO diet (P < 0.01). The ratio apoB:apoA-I was 10.4 % higher in subjects on the PHFO diet than on the VO diet (P < 0.01). There were no significant differences in total cholesterol, HDL-cholesterol, triacylglycerols, apoB, lipoprotein(a) and haemostatic variables between the diets. Our results demonstrate that PHFO, with its unfavourable effects on plasma lipids, can be replaced by vegetable oils in margarine without appreciable loss of functional properties but with significant improvement in the effects on plasma lipoproteins.
DNA Damage, Glutathione, and Total Antioxidant Capacity in Anesthesia Nurses

ABSTRACT The possibilities of a potential mutagenic/carcinogenic action of waste anesthetic gases in occupationally exposed anesthesia personnel have been previously reported in several studies. The aim of this study was to assess the DNA damage, reduced glutathione (GSH), and total antioxidant capacity (TAC) in anesthesia nurses. DNA damage was determined with comet assay, GSH levels were measured spectrophotometrically, and TAC was determined by using Randox kit. Anesthesia nurses (n = 40) showed increased DNA damage in terms of mean percentage of the total DNA in the comet tail compared to controls (n = 40) (p < .001). Mean TAC and GSH levels of the anesthesia nurses were significantly lower than that of the controls (p < .001, p < .05, respectively). The results of this study indicate that occupational exposure to anesthetic gases induce DNA damage, which may lead to changes in TAC and GSH levels.
Neural sources involved in auditory target detection and novelty processing: an event-related fMRI study.

We used event-related functional magnetic resonance imaging (erfMRI) techniques to examine the cerebral sites involved with target detection and novelty processing of auditory stimuli. Consistent with the results from a recent erfMRI study in the visual modality, target processing was associated with activation bilaterally in the anterior superior temporal gyrus, inferior and middle frontal gyrus, inferior and superior parietal lobules, anterior and posterior cingulate, thalamus, caudate, and the amygdala/hippocampal complex. Analyses of the novel stimuli revealed activation bilaterally in the inferior frontal gyrus, insula, inferior parietal lobule, and in the inferior, middle, and superior temporal gyri. These data suggest that the scalp recorded event-related potentials (e.g., N2 and P3) elicited during similar tasks reflect an ensemble of neural generators located in spatially remote cortical areas.
Frontiers in Integrative Neuroscience Integrative Neuroscience Materials and Methods Animal Preparation

This study focuses on the role of MD in the timing of actions, using the action differentiation paradigm. Action differentiation is the process by which different actions are generated despite identical stimulus conditions (Platt et al. Here we examined the temporal differentiation of action duration (the period between the pressing and the release of a lever) and inter-response-times (IRT, time between two adjacent lever presses) to further investigate the role of the MD in instrumental learning. We used 65 male Long–Evans rats (∼7 weeks at the beginning of the experiments). All procedures followed Duke University Animal Care and Use Committee guidelines. Surgery was performed under general anesthesia with isofl urane (2%). Anesthetized animals were mounted in a stereotaxic device (Kopf, CA, USA). The scalp was cut to expose the skull surface and small burr holes were drilled bilaterally (AP −3.0; ML ±0.7 − 0.8; DV −5.5). Lesions were created by infusing 0.4 µl NMDA (0.1 M in PBS) per side over 2 min; and to allow the drug to diffuse, the needle was left in the brain for another 5 min after the end of injection. Sham lesions were created using the same procedures except 0.9% saline was injected instead of NMDA. Training took place in six Med Associates (St. Albans, VT, USA) operant chambers. Rats were food deprived by feeding them 10–12 g of home chow each day after training and testing, to maintain their body weight at about 85% of their normal weight. Water was always available in the home cages. Each chamber was equipped with a food magazine that received pellets from a pellet dispenser (Bio-Serv 45 mg dustless precision pellets, Bio-Serv,
Distribution, magnitudes, reactivities, ratios and diurnal patterns of volatile organic compounds in the Valley of Mexico during the MCMA 2002 & 2003 field campaigns

A wide array of volatile organic compound (VOC) measurements was conducted in the Valley of Mexico during the MCMA-2002 and 2003 field campaigns. Study sites included locations in the urban core, in a heavily industrial area and at boundary sites in rural landscapes. In addition, a novel mobile-laboratory-based conditional sampling method was used to collect samples dominated by fresh on-road vehicle exhaust to identify those VOCs whose ambient concentrations were primarily due to vehicle emissions. Four distinct analytical techniques were used: whole air canister samples with Gas Chromatography/Flame Ionization Detection (GC-FID), on-line chemical ionization using a Proton Transfer Reaction Mass Spectrometer (PTR-MS), continuous real-time detection of olefins using a Fast Olefin Sensor (FOS), and long path measurements using UV Differential Optical Absorption Spectrometers (DOAS). The simultaneous use of these techniques provided a wide range of individual VOC measurements with different spatial and temporal scales. The VOC data were analyzed to understand concentration and spatial distributions, diurnal patterns, origin and reactivity in the atmosphere of Mexico City. The VOC burden (in ppbC) was dominated by alkanes (60%), followed by aromatics (15%) and olefins (5%). The remaining 20% was a mix of alkynes, halogenated hydrocarbons, oxygenated species (esters, ethers, etc.) and other unidentified VOCs. However, in terms of ozone production, olefins were the most relevant hydrocarbons. Elevated levels of toxic hydrocarbons, such as 1,3-butadiene, benzene, toluene and xylenes, were also observed. Results from these various analytical techniques showed that vehicle exhaust is the main source of VOCs in Mexico City and that diurnal patterns depend on vehicular traffic in addition to meteorological processes. Finally, examination of the VOC data in terms of lumped modeling VOC classes and its comparison to the VOC lumped emissions reported in other photochemical air quality modeling studies suggests that some alkanes are underestimated in the emissions inventory, while some olefins and aromatics are overestimated.
Effect of tibial plateau leveling on cranial and caudal tibial thrusts in canine cranial cruciate-deficient stifles: an in vitro experimental study.

OBJECTIVES To investigate the effect of tibial plateau leveling (TPL) on tibial subluxation and tibial axial rotation; to determine the minimal tibial plateau rotation (MinTPR) angle that provides stifle stability; and to evaluate caudal cruciate ligament (CaCL) strain following tibial plateau rotation in cranial cruciate ligament (CrCL)-deficient stifles. ANIMALS Fifteen canine cadaver hind limbs. METHODS Tibial subluxation was measured from lateral radiographs in intact, loaded stifles and after sequential CrCL transection, MinTPR, TPL, and CaCL transection. The MinTPR angle was determined using a custom-made hinge plate and compared with the TPL angle. Tibial axial rotation was evaluated in CrCL-deficient stifles before and after TPL. Finally, CaCL strain was recorded in intact, loaded stifles, and following MinTPR, TPL, and tibial plateau over-rotation (MaxTPR) using a force probe. RESULTS Cranial tibial subluxation in CrCL-deficient stifles was eliminated with TPL. Tibial plateau rotation, however, induced caudal tibial subluxation, which significantly increased from MinTPR to TPL before and after CaCL transection. The MinTPR angle was 6.5 degrees +/- 0.9 degrees less than the TPL angle (P <.05). Tibial internal rotation decreased significantly after TPL in CrCL-deficient stifles. Finally, CaCL strain increased with increasing tibial plateau rotation. CONCLUSIONS This study suggests that, during stance phase, TPL transforms cranial tibial thrust into caudal tibial thrust, thereby stabilizing the stifle in the cranio-caudal plane via the constraint of the CaCL. The increase in CaCL stress, which results from tibial plateau rotation, could predispose the CaCL to fatigue failure and therefore would caution against tibial plateau over-rotation.
Control algorithms for a fault-tolerant PMSM drive

This paper proposes control algorithms for a fault-tolerant permanent-magnet synchronous motor (PMSM) drive. In order to improve the reliability of the drive, an algorithm for achieving sensorless control that operates properly also in fault mode is proposed. Furthermore, it is shown how a closed-loop field-weakening controller needs to be modified in order to operate properly in fault mode. The application in mind is electric vehicle propulsion and the algorithms presented are verified with experimental results using an in-wheel PMSM. With the proposed modifications, the reliability of the drive can be increased.