Miracle-dz/UniFAR-FTUs huggingface dataset:
The Impact of Social Media on Leetchi Crowdfunding Projects Success

Crowdfunding platforms have known an increasing interest during the last decade. The global crowdfunding industry estimates the fundraising volume to be up to $60 Billion in 2016, surpassing traditional forms of finance. Crowdfunding by counterparts and lending have been extensively studied but, until now, only a small amount of research was focused on donation-based platforms. In this paper, we propose a first analysis of the Leetchi donation crowdfunding platform and of an impact of social network activity on project success. The project success insights covered in this article could guide the project owners into more successful decisions and strategies on social media. We collected and analyzed the Twitter activity related to Leetchi projects from November 1st to November 30th , 2016 obtaining a set of 19,000 tweets mentioning 438 Leetchi projects. We define and investigate seven social media features: the number of tweets, number of profiles, number of influencers, audience of the top influencer, the average number of followers and friends and statuses of people mentioning the projects. We also model Leetchi social media campaigns as a diffusion graph and extend our analysis with eight additional features: the order, the size, the number of connected components, the average in/out-degrees, the weighted average in/out-degrees and the density of the diffusion graph. Finally, we study the predictive power of all 15 features on the various levels of success of Leetchi projects using machine learning algorithms. We found that while traditional social media metrics allows predicting the reach of small funding (from 1€ to 100€), social network features allow better distinguish projects with a high level of funding (from 100€ to 1,000€).
Efficient Lookup Table-Based Adaptive Baseband Predistortion Architecture for Memoryless Nonlinearity

Digital predistortion is an effective means to compensate for the nonlinear effects of a memoryless system. In case of a cellular transmitter, a digital baseband predistorter can mitigate the undesirable nonlinear effects along the signal chain, particularly the nonlinear impairments in the radiofrequency (RF) amplifiers. To be practically feasible, the implementation complexity of the predistorter must be minimized so that it becomes a cost-effective solution for the resource-limited wireless handset. This paper proposes optimizations that facilitate the design of a low-cost high-performance adaptive digital baseband predistorter for memoryless systems. A comparative performance analysis of the amplitude and power lookup table (LUT) indexing schemes is presented. An optimized low-complexity amplitude approximation and its hardware synthesis results are also studied. An efficient LUT predistorter training algorithm that combines the fast convergence speed of the normalized least mean squares (NLMSs) with a small hardware footprint is proposed. Results of fixed-point simulations based on the measured nonlinear characteristics of an RF amplifier are presented.
Analysis of Team Effectiveness at Center of Development and Empowerment for Teachers and Education Personnel Medan

This study tried to describe data of team effectiveness at Center of Development and Empowerment for Teachers and Education Personnel Medan and find out the indicators that are still weak on team effectiveness variables for enhanced in the future. Respondents are trainers and staff with a number of 127 people. Analysis of the data by using descriptive analysis. The results showed the highest scoring team effectiveness is 120, the lowest score is 64, the mean is 102.47 and standard deviation is 13.21, while the ideal highest score is 120, the ideal lowest score is 24, and the ideal mean score is 72 and ideal standard deviation is 16. Data tendency team effectiveness is 73.23% in the high category, 24.41% in the enough category and 2.36% in the low category. Indicators of team effectiveness in this study were achievement of the objectives, quality of work, timeliness of completion and creativity of unit. The weakness indicators of all are is the creativity of unit.
Plasma brain-derived neurotrophic factor in women with pelvic pain: a potential biomarker for endometriosis?

AIM To test whether plasma BDNF levels are useful to predict the presence of endometriosis in women with pelvic pain. PATIENTS & METHODS Prospective cross-sectional study including 67 consecutive women aged 24-49 years, scheduled for laparoscopy due to chronic pelvic pain. Preoperative plasma samples were assayed for BDNF using a commercial enzyme immunoassay. RESULTS Women with ovarian endometrioma had higher preoperative plasma BDNF (1063 ± 157 pg/ml) compared with women with other benign ovarian tumors (537 ± 131 pg/ml, F = 2.53; p = 0.02). However, plasma BDNF levels were not helpful to indicate the presence of peritoneal or deep infiltrating endometriosis. Plasma BDNF levels were positively correlated with the severity of pelvic pain (r = 0.489; p < 0.0001). CONCLUSION Plasma BDNF might be a biomarker of ovarian endometrioma but not a useful diagnostic marker to detect other forms of endometriosis in women with painful symptoms.
American Thoracic Society Documents An Official ATS / ERS / JRS / ALAT Statement : Idiopathic Pulmonary Fibrosis : Evidence-based Guidelines for Diagnosis and Management

Ganesh Raghu, Harold R. Collard, Jim J. Egan, Fernando J. Martinez, Juergen Behr, Kevin K. Brown, Thomas V. Colby, Jean-Franc xois Cordier, Kevin R. Flaherty, Joseph A. Lasky, David A. Lynch, Jay H. Ryu, Jeffrey J. Swigris, Athol U. Wells, Julio Ancochea, Demosthenes Bouros, Carlos Carvalho, Ulrich Costabel, Masahito Ebina, David M. Hansell, Takeshi Johkoh, Dong Soon Kim, Talmadge E. King, Jr., Yasuhiro Kondoh, Jeffrey Myers, Nestor L. Müller, Andrew G. Nicholson, Luca Richeldi, Moisés Selman, Rosalind F. Dudden, Barbara S. Griss, Shandra L. Protzko, and Holger J. Schünemann, on behalf of the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis
MANAGEMENT CONTROL SYSTEMS DURING EARLY LIFE CYCLE PHASES A case study in the social and healthcare services sector Master’s Thesis

OBJECTIVES OF THE STUDY The objective of this study is to investigate how and why an organization’s management control systems (MCS) package evolves during the birth and growth life cycle phases. As an organization grows, its administrative task becomes greater, and thus its control needs are expected to increase. This thesis will provide a holistic view of the changes in each element of the MCS package while also examining their interdependence. It will employ a life cycle perspective to capture the dynamic nature of organizational life. DATA AND METHODOLOGY The research was conducted as a case study using a single case company in the Finnish social and healthcare services sector. A qualitative approach was selected because of the high level of depth required to satisfactorily meet the objectives of the study. While some aspects of the MCS package can easily be identified, others can be more difficult to uncover. The main sources of data were 12 interviews supplemented with participant observation.
Contact inhibition of speed in 3T3 and its independence from postconfluence inhibition of cell division

The average speed of nuclear translocation of 3T3 cells, recorded in a time‐lapse film of a perfused culture, was negatively correlated with the number of contacting cells, and, to a lesser degree, with the amount of a cell's perimeter in contact with other cells. When a cell was in contact with five or more other cells, its speed was reduced by 50%, on the average, although the variation in individual cell speed was considerable at each level of contact. A partial correlation analysis showed that any extracellular soluble factors governed by the local cell density had little or no effect on speed, relative to the prominent effect of the number of cell‐cell contacts, and hence that 3T3 cells display true contact inhibition of speed. This confirms the original demonstration by Abercrombie and Heaysman (1952), who studied chick embryo heart fibrpolasts. In our study, the relationships between average speed and age of the culture was such that a possible independent contribution of a time‐associated factor other than contact to the diminution in average speed, although not necessary to account for the data, could not be excluded.
Thinking through breasts

This article begins by wondering how the writer’s transformation into motherhood affects her practice of reading, writing and research: how maternities are made academic. Specifically, this article is interested in thinking through lactating breasts, as a particularly complex and potentially subversive ‘performance’ of maternity. In addition, this article reframes ‘maternal thinking’ through 1990s theories of embodiment and corporeality, and asks how embodied practices like breastfeeding might be theorized, as well as how ‘embodied theory’ might be practised. In looking at various cultural texts about breasts and breastfeeding, the article is scripted into a series of connective and reflexive scenes around performance, space, language and knowledge, coming to rest in the imaginative project of an epistemology of breasts. It sets reflexive accounts of lived experience alongside theoretical reflections to create a dynamic and thoughtful reading of breasts, entwining personal and public discourses, maternal and academic writing, theorizing and cultural practices.
Developmental expression of the actin depolymerizing factor ADF in the mouse inner ear and spiral ganglia

Hair cells, the inner ear's sensory cells, are characterized by tens to hundreds of actin‐rich stereocilia that form the hair bundle apparatus necessary for mechanoelectrical transduction. Both the number and length of actin filaments are precisely regulated in stereocilia. Proper cochlear and vestibular function also depends on actin filaments in nonsensory supporting cells. The formation of actin filaments is a dynamic, treadmill‐like process in which actin‐binding proteins play crucial roles. However, little is known about the presence and function of actin binding molecules in the inner ear, which set up, and maintain, actin‐rich structures and regulate actin turnover. Here we examined the expression and subcellular location of the actin filament depolymerizing factor (ADF) in the cochlea and vestibular organs. By means of immunocytochemistry and confocal microscopy, we analyzed whole‐mount preparations and cross‐sections in fetal and postnatal mice (E15–P26). We found a transient ADF expression in immature hair cells of the organ of Corti, the utricle, and the saccule. Interestingly, the stereocilia were not labeled. By P26, ADF expression was restricted to supporting cells. In addition, we localized ADF in presynaptic terminals of medio‐olivocochlear projections after hearing onset. A small population of spiral ganglion neurons strongly expressed ADF. Based on their relative number, peripheral location within the ganglion, smaller soma size, and coexpression of neurofilament 200, we identified these cells as Type II spiral ganglion neurons. The developmentally regulated ADF expression suggests a temporally restricted function in the stereocilia and, thus, a hitherto undescribed role of ADF. J. Comp. Neurol. 518:1724–1741, 2010. © 2009 Wiley‐Liss, Inc.
Steroids in leptospiral uveitis: Does the route of administration matter?

Treatment of leptospiral uveitis primarily consists of steroid therapy[4] ocular as topical preparations, or posterior sub tenon (PST) steroid injections, and systemic steroid supplementation. We looked at the records of patients with leptospiral uveitis with a view to correlate the modality of steroid administration with clinical treatment outcomes, namely an improvement in visual acuity and decrease of inflammatory reaction in the affected eyes.
Multiple selection filters ensure accurate tail-anchored membrane protein targeting

Accurate protein localization is crucial to generate and maintain organization in all cells. Achieving accuracy is challenging, as the molecular signals that dictate a protein’s cellular destination are often promiscuous. A salient example is the targeting of an essential class of tail-anchored (TA) proteins, whose sole defining feature is a transmembrane domain near their C-terminus. Here we show that the Guided Entry of Tail-anchored protein (GET) pathway selects TA proteins destined to the endoplasmic reticulum (ER) utilizing distinct molecular steps, including differential binding by the co-chaperone Sgt2 and kinetic proofreading after ATP hydrolysis by the targeting factor Get3. Further, the different steps select for distinct physicochemical features of the TA substrate. The use of multiple selection filters may be general to protein biogenesis pathways that must distinguish correct and incorrect substrates based on minor differences. DOI: http://dx.doi. org/10.7554/eLife.21301. 001
ACE 2 / Ang-( 1 – 7 ) / Mas axis stimulates vascular repair-relevant functions of CD 34 cells

Neha Singh, Shrinidh Joshi, Lirong Guo, Matthew B. Baker, Yan Li, Ronald K. Castellano, Mohan K. Raizada, and Yagna P. R. Jarajapu Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota; Department of Pathophysiology, College of Basic Medical Science, Jilin University, Changchun, Jilin, China; Department of Chemistry, University of Florida, Gainesville, Florida; and Department of Physiology and Functional Genomics, College of Medicine, University of Florida, Gainesville, Florida
The Influence of Shyness on the Use of Facebook in an Undergraduate Sample

Researchers have suggested that individual differences will help to determine which online communication tools appeal to and are used by different individuals. With respect to the domain of computer-mediated communication, shyness is a particular personality trait of interest, as forums provide opportunities for social interactions that shy individuals might otherwise avoid. The present study investigated the personality trait of shyness and its relation with certain features of an online communication tool (Facebook). We hypothesized that shyness would be significantly related to the quantity of time spent on Facebook, the number of contacts added to one's Facebook profile, and attitudes toward Facebook. Our findings supported that shyness was significantly positively correlated with the time spent on Facebook and having favorable attitudes toward the social networking site. Furthermore, shyness was significantly negatively correlated with the number of Facebook "Friends. '' Limitations of the present study and suggestions for future research are addressed.
Molecular and Pharmacological Characterization of Serotonin 5-HT2α and 5-HT7 Receptors in the Salivary Glands of the Blowfly Calliphora vicina

Secretion in blowfly (Calliphora vicina) salivary glands is stimulated by the biogenic amine serotonin (5-hydroxytryptamine, 5-HT), which activates both inositol 1,4,5-trisphosphate (InsP3)/Ca2+ and cyclic adenosine 3′,5′-monophosphate (cAMP) signalling pathways in the secretory cells. In order to characterize the signal-inducing 5-HT receptors, we cloned two cDNAs (Cv5-ht2α, Cv5-ht7) that share high similarity with mammalian 5-HT2 and 5-HT7 receptor genes, respectively. RT-PCR demonstrated that both receptors are expressed in the salivary glands and brain. Stimulation of Cv5-ht2α-transfected mammalian cells with 5-HT elevates cytosolic [Ca2+] in a dose-dependent manner (EC50 = 24 nM). In Cv5-ht7-transfected cells, 5-HT produces a dose-dependent increase in [cAMP]i (EC50 = 4 nM). We studied the pharmacological profile for both receptors. Substances that appear to act as specific ligands of either Cv5-HT2α or Cv5-HT7 in the heterologous expression system were also tested in intact blowfly salivary gland preparations. We observed that 5-methoxytryptamine (100 nM) activates only the Cv5-HT2α receptor, 5-carboxamidotryptamine (300 nM) activates only the Cv5-HT7 receptor, and clozapine (1 µM) antagonizes the effects of 5-HT via Cv5-HT7 in blowfly salivary glands, providing means for the selective activation of each of the two 5-HT receptor subtypes. This study represents the first comprehensive molecular and pharmacological characterization of two 5-HT receptors in the blowfly and permits the analysis of the physiological role of these receptors, even when co-expressed in cells, and of the modes of interaction between the Ca2+- and cAMP-signalling cascades.
Bronchopulmonary dysplasia: incidence, risk factors and resource utilization in a population of South American very low birth weight infants.

OBJECTIVE To determine the incidence of bronchopulmonary dysplasia, its risk factors and resource utilization in a large South American population of very low birth weight infants. METHODS Prospectively collected data in infants weighing 500 to 1,500 g born at 16 NEOCOSUR Network centers from 10/2000 through 12/2003. Multivariate relative risk and 95% confidence intervals were estimated by Poisson regression with robust error variance to find factors that affected the risk of bronchopulmonary dysplasia. RESULTS 1,825 very low birth weight infants survivors were analyzed. Mean birth weight and gestational age were 1085+/-279 g and 29+/-3 weeks respectively. Bronchopulmonary dysplasia incidence averaged 24.4% and survival without bronchopulmonary dysplasia augmented with increasing gestational age. A higher birth weight and gestational age and a female gender all decreased the risk for bronchopulmonary dysplasia. Factors that independently increased that risk were surfactant requirement, mechanical ventilation, airleak, patent ductus arteriosus, late onset sepsis and necrotizing enterocolitis. Bronchopulmonary dysplasia infants had more days of hospitalization (91+/-27 vs. 51+/-19), of mechanical ventilation (19+/-20 vs. 4+/-7) and oxygen therapy (72+/-30 vs. 8+/-14) in comparison with non BPD infants. CONCLUSIONS Bronchopulmonary dysplasia incidence was 24.4% in a large South American population and is related to greater resource utilization. Risk factors for bronchopulmonary dysplasia in this study were: surfactant requirement, mechanical ventilation, airleak, patent ductus arteriosus, late onset sepsis and necrotizing enterocolitis. These studies may provide useful information in the design of effective preventive perinatal strategies.
Impact of Biopsychosocial Factors on Chronic Pain in Persons With Myotonic and Facioscapulohumeral Muscular Dystrophy

To assess the role of biopsychosocial factors in patients with type 1 myotonic and facioscapulohumeral muscular dystrophy (MMD1/FSHD) with chronic pain. Associations between psychosocial factors were found to be important in other samples of persons with pain and both psychological functioning and pain interference in a sample of patients suffering from MMD/FSHD. Prospective, multiple group, survey study of 182 patients with confirmed MMD1 and FSHD. Participants completed surveys assessing pain interference and psychological functioning, as well as psychosocial, demographic, and injury-related variables. Analyses indicated that greater catastrophizing was associated with increased pain interference and poorer psychological functioning, pain attitudes were significantly related to both pain interference and psychological functioning, and coping responses were significantly related only to pain interference. In addition, greater perceived social support was associated with better psychological functioning. The results support the use of studying pain in persons with MMD/FSHD from a biopsychosocial perspective, and the importance of identifying psychosocial factors that may play a role in the adjustment to and response to pain secondary to MMD/FSHD.
Chronic Maternal Vitamin B12 Restriction Induced Changes in Body Composition & Glucose Metabolism in the Wistar Rat Offspring Are Partly Correctable by Rehabilitation

Maternal under-nutrition increases the risk of developing metabolic diseases. We studied the effects of chronic maternal dietary vitamin B12 restriction on lean body mass (LBM), fat free mass (FFM), muscle function, glucose tolerance and metabolism in Wistar rat offspring. Prevention/reversibility of changes by rehabilitating restricted mothers from conception or parturition and their offspring from weaning was assessed. Female weaning Wistar rats (n = 30) were fed ad libitum for 12 weeks, a control diet (n = 6) or the same with 40% restriction of vitamin B12 (B12R) (n = 24); after confirming deficiency, were mated with control males. Six each of pregnant B12R dams were rehabilitated from conception and parturition and their offspring weaned to control diet. While offspring of six B12R dams were weaned to control diet, those of the remaining six B12R dams continued on B12R diet. Biochemical parameters and body composition were determined in dams before mating and in male offspring at 3, 6, 9 and 12 months of their age. Dietary vitamin B12 restriction increased body weight but decreased LBM% and FFM% but not the percent of tissue associated fat (TAF%) in dams. Maternal B12R decreased LBM% and FFM% in the male offspring, but their TAF%, basal and insulin stimulated glucose uptake by diaphragm were unaltered. At 12 months age, B12R offspring had higher (than controls) fasting plasma glucose, insulin, HOMA-IR and impaired glucose tolerance. Their hepatic gluconeogenic enzyme activities were increased. B12R offspring had increased oxidative stress and decreased antioxidant status. Changes in body composition, glucose metabolism and stress were reversed by rehabilitating B12R dams from conception, whereas rehabilitation from parturition and weaning corrected them partially, highlighting the importance of vitamin B12 during pregnancy and lactation on growth, muscle development, glucose tolerance and metabolism in the offspring.
Early Life Traumatic Stressors and the Mediating Role of PTSD in Incident HIV Infection Among US Men, Comparisons by Sexual Orientation and Race/Ethnicity: Results From the NESARC, 2004–2005

Background:Stressful life events in childhood during critical periods of development have long-term psychological and neurobiological sequelae, which may affect risk for HIV infection across the life course. Methods:Data were from a nationally representative sample of 13,274 US men (National Epidemiologic Survey on Alcohol and Related Conditions, 2004-2005). Weighted multivariable logistic regression models examined (1) the association of childhood violent events before age 18 on 12-month incident HIV infection and (2) whether posttraumatic stress disorder (PTSD) diagnosis (clinical interview) mediated the association between early life events and HIV. Results:Overall, the 12-month HIV incidence was <1% (0.35%); 44% of new infections were among racial/ethnic minorities and 31% among men who have sex with men). One-third of the sample (33.5%) reported one or more early life stressors (physical abuse, sexual abuse, neglect, verbal violence, or witnessed violence). In a weighted multivariable logistic regression model adjusted for age, education, family's socioeconomic position, and sexual behaviors, each additional early life violent event was associated with an elevated odds of HIV infection [adjusted odds ratio (aOR) = 1.32; 95% confidence interval (CI): 1.16 to 1.50]. Adding PTSD to this adjusted model, PTSD was highly associated with incident HIV infection (aOR = 5.75; 95% CI: 4.76 to 6.95). There was evidence that PTSD partially mediated the relationship between early life events and HIV (aOR = 1.14; 95% CI: 1.02 to 1.28). Conclusions:Experiencing early life violent family stressors was associated with HIV infection among men. Early life events and HIV infection were mediated by PTSD, which has implications for understanding disparities in HIV infection. Interventions are urgently needed that address the long-term sequelae of childhood violence.