Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification of a virB10 protein aggregate in the inner membrane of Agrobacterium tumefaciens

Products of the virB operon are proposed components of a membrane-associated T-DNA transport apparatus in Agrobacterium tumefaciens. Here we identified the virB10 gene product and raised specific antiserum to the protein. While the virB10 reading frame contains two potential ATG translation start sites located 32 codons apart, we found that only the downstream ATG was required for efficient VirB10 synthesis. Cellular localization studies and analysis of translational fusions with the Escherichia coli alkaline phosphatase gene (phoA) indicated that VirB10 was anchored in the inner membrane and contained a periplasmic domain. This work also demonstrated the utility of alkaline phosphatase as a reporter for secreted proteins in A. tumefaciens. Several high-molecular-weight forms of VirB10 were observed after treatment of A. tumefaciens whole cells or inner membranes with protein cross-linking agents, suggesting that VirB10 exists as a native oligomer or forms an aggregate with other membrane proteins. These results provide the first biochemical evidence that a VirB protein complex is membrane associated in A. tumefaciens.
Who looks for casual dates on the internet? A test of the compensation and the recreation hypotheses

Research has dealt with the consequences of seeking casual partners online, but has been silent about its antecedents. To address this research gap, this study tested two hypotheses. The compensation hypothesis states that people high in dating anxiety and low in physical self-esteem seek casual dates online because the features of online communication (e.g. reduced cues, anonymity, controllability) allow them to compensate for the deficits experienced in offline dating. The recreation hypothesis proposes that sexually-permissive people and high sensation-seekers will look for casual partners online because they value the anonymity of the internet. Multivariate analyses of a survey of 729 Dutch adults supported the recreation hypothesis, but not the compensation hypothesis. Sexually-permissive people and high sensation-seekers looked for casual partners online more frequently than sexually-restrictive people and low sensation-seekers. Dating anxiety and physical self-esteem, in contrast, were unrelated to the seeking of casual partners online.
Hemispheric interaction: when and why is yours better than mine?

ix Table of contents xi Table of Figures xv Chapter 1 1 1.1 General Introduction 1 1.1.1 Historical Perspective 1 1.2 Hemispheric Interaction: What? Where? How? 5 1.3 Hemispheric Interaction and Behaviour 6 1.3. 1 Meta-Control 6 1.3. 2 Resource Sharing across Hemispheres: the Bilateral Distribution Advantage (BDA) 7 1.3. 3 Hemispheric Interaction, Functional Lateralisation, and Handedness . 11 1.3. 4 Hemispheric Interaction and Sex 12 1.3. 5 Hemispheric Interaction with Regard to Age 13 1.3. 6 Hemispheric Interaction and Attention 15 1.3. 7 Hemispheric Interaction and Practice 17 1.4 Interhemispheric Transfer and the Corpus Callosum 17 1.4. 1 Corpus Callosum: Structure and Function 18 1.4. 2 Corpus Callosum Development 22 1.4. 3 The Corpus Callosum, Lateralisation and Handedness 23 1.4. 4 Sexual Dimorphism of the Corpus Callosum 23 1.4. 5 Corpus Callosum and Ageing 24 1.4. 6 Behavioural Implications of Callosal Differences 25 1.5 Summary 28 Chapter 2 31 2.1 Methodology 31 2.2 The Measurement of Interhemispheric Transfer Time 31 2.2.1 Validity of the CUD as a Measure of IHTT 33 2.2.2 Variability of the CUD 35 2.2.3 Pathways Underlying Interhemispheric Transfer in the Poffenberger Paradigm 35 2.3 The Measurement of Hemispheric Interactions 37 2.3. 1 Number of Stimuli 38 2.3. 2 Stimulus Eccentricities 39 2.3. 3 Type of Match 39 2.3. 4 Shape of the Display 40 2.3. 5 Experiment 1 41 2.3. 6 Motor response 47
First-principles study of diffusion of Li, Na, K and Ag in ZnO

Based on ab initio total energy calculations, Li, Na and Ag interstitials are found to be stable with at least a 1.56 eV energy barrier to transform to a zinc substitutional site in ZnO, whereas K interstitial has a relatively small energy barrier at 0.79 eV. The isolated dopant substitutional defects (LiZn, NaZn, KZn and AgZn) are found to be rather stable, with at least a 3.4 eV energy barrier to transform to an interstitial site. All of the dopant interstitials (Lii, Nai, Ki and Agi) are fast diffusers. The diffusion of Li interstitial is isotropic, whereas the diffusion of Na, K and Ag interstitials is highly anisotropic. Fundamental processes of the vacancy-assisted mechanisms are systematically investigated and specific values of the energy barriers are obtained.
Electrophysiological Correlates of Age and Gender Perception on Human Faces

In a previous experiment using scalp event-related potentials (ERPs), we have described the neuroelectric activities associated with the processing of gender information on human faces (Mouchetant-Rostaing, Giard, Bentin, Aguera, & Pernier, 2000). Here we extend this study by examining the processing of age on faces using a similar experimental paradigm, and we compare age and gender processing. In one session, faces were of the same gender (women) and of one age range (young or old), to reduce gender and age processing. In a second session, faces of young and old women were randomly intermixed but age was irrelevant for the task, hence, age discrimination, if any, was assumed to be incidental. In the third and fourth sessions, faces had to be explicitly categorized according to their age or gender, respectively (intentional discrimination). Neither age nor gender processing affected the occipito-temporal N170 component often associated with the detection of physiognomic features and global structural encoding of faces. Rather, the three age and gender discrimination conditions induced similar fronto-central activities around 145185 msec. In our previous experiment, this ERP pattern was also found for implicit and explicit categorization of gender from faces but not in a control condition manipulating hand stimuli (Mouchetant-Rostaing, Giard, Bentin, et al., 2000). Whatever their exact nature, these 145185 msec effects therefore suggest, first, that similar mechanisms could be engaged in age and gender perception, and second, that age and gender may be implicitly processed irrespective of their relevance to the task, through somewhat specialized mechanisms. Additional ERP effects were found at early latencies (4590 msec) in all three discrimination conditions, and around 200400 msec during explicit age and gender discrimination. These effects have been previously found in control conditions manipulating nonfacial stimuli and may therefore be related to more general categorization processes.
Support for families : helping children with learning disabilities

Part 1 Background: children with disabilities - an overview families and communities labelling and learning disabilities - a special case for research. Part 2 The research findings: the experience of learning disability in the family family support - informal networks family support - formal networks illustrations of learning disabilities in the family conclusions - getting the best for our children.
Exact Analysis of the Recurrence Relations Generalized from the Tower of Hanoi

In this paper, we analyze the recurrence relations generalized from the Tower of Hanoi problem of the form T(n, α, β) = min1≤t≤n{α T(n − t, α, β)+β S(t, 3)}, where S(t, 3) = 2t − 1 is the optimal solution for the 3-peg Tower of Hanoi problem. It is shown that when α and β are natural numbers and α ≥ 2, the sequence of differences of T(n, α, β)'s, i.e., T(n, α, β) − T(n − 1, α, β), consists of numbers of the form β2iαj (i, j ≥ 0) lined in the increasing order.
Plans as Emotion Regulation Tools? Examining the Consequences of Planning on Affect

Psychologists have studied extensively the consequences of planning for motivation and task performance, but little work has examined whether plan-making serves another function, that of helping us feel better about the yet-to-be completed task. In the present research, we examined whether making plans for completing a future task positively impacts feelings related to that task. In three studies, we tested the possibility that planning decreases negative emotions about the task planned for, and whether some types of planning are more beneficial for this than others. In Studies 1 and 2, participants were asked to nominate an important task they had yet to complete and that they had felt concerned about completing lately, and then instructed to either make a plan to complete the task using one of the specified planning types, or were not asked to make a plan. Participants then rated their feelings about the task on twenty emotions adjectives (PANAS; Watson, Clark, & Tellegen, 1988). In Study 3, participants were prompted to think about an upcoming exam, and then either (1) made a specific plan to prepare for it followed by giving affect ratings (experimental condition), or (2) rated their affect first and then made a specific plan (control condition). The results of Study 1 (N = 144) supported our hypothesis – following planning, mental simulation planners reported lower levels of negative affect than implementation intention planners and no plan controls. No differences were found for positive affect. These results were not replicated in Study 2 (N = 133) or Study 3 (N = 147), where feelings about the task did not differ depending on whether participants planned or not, or planning type. Overall, our findings did not yield consistent evidence that planning for an important future task has immediate affective benefits.
Pregnancy With SLE and Fetal Congenital Heart Block: A Case Report

Autoimmune AV block is usually seen in association with autoimmune antibodies in mother that cross the placenta and damage the AV node of fetus. A 24-year-old primigravida, diagnosed to have SLE, at 25 weeks period of gestation found to have fetal bradycardia. Her ANA was moderately positive, SS-A (Ro) antibodies and SS-B (La) antibodies were positive. Fetal ECHO showed no structural defect but heart rate was 55 - 60 beats per minute. She was put on dexamethasone (4 mg/day). She was lost on follow up and presented at term in emergency with labor pains and fetal bradycardia, underwent a lower segment caesarean section. Baby underwent a temporary cardiac pacing within 10 hours of birth followed by permanent pacing on day 3 of birth. Baby is doing well on follow up. Neonates with isolated congenital heart block who are monitored antenatally and delivered in a planned fashion at an institution capable of early pacing can have favorable outcomes.
Differential effects of acute alcohol on prepulse inhibition and event-related potentials in adolescent and adult Wistar rats.

BACKGROUND Previous studies have demonstrated that adolescent and adult rats show differential sensitivity to many of the acute effects of alcohol. We recently reported evidence of developmental differences in the effects of acute alcohol on the cortical electroencephalogram. However, it is unclear whether developmental differences are also observed in other neurophysiological and neurobehavioral measurements known to be sensitive to alcohol exposure. The present study determined the age-related effects of acute alcohol on behavioral and event-related potential (ERP) responses to acoustic startle (AS) and prepulse inhibition (PPI). METHODS Male adolescent and adult Wistar rats were implanted with cortical recording electrodes. The effects of acute alcohol (0.0, 0.75, and 1.5 g/kg) on behavioral and ERP responses to AS and PPI were assessed. RESULTS Acute alcohol (0.75 and 1.5 g/kg) significantly reduced the behavioral and electrophysiological response to AS in adolescent and adult rats. Both 0.75 and 1.5 g/kg alcohol significantly enhanced the behavioral response to PPI in adolescent, but not in adult rats. During prepulse + pulse trials, 1.5 g/kg alcohol significantly increased the N10 pulse response in the adolescent frontal cortex. Acute alcohol (0.75 and 1.5 g/kg) also increased the N1 ERP pulse response to prepulse stimuli in frontal and parietal cortices in adult rats, but not in adolescent rats. CONCLUSIONS These data suggest that alcohol's effect on behavioral and electrophysiological indices of AS do not differ between adults and adolescents whereas developmental stage does appear to significantly modify alcohol-influenced response to PPI.
Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of the variation in protein levels, indicating dominant post-transcriptional effects. However, the techniques underlying these conclusions, such as correlation and regression, yield biased results when data are noisy, missing systematically, and collinear—properties of mRNA and protein measurements—which motivated us to revisit this subject. Noise-robust analyses of 24 studies of budding yeast reveal that mRNA levels explain more than 85% of the variation in steady-state protein levels. Protein levels are not proportional to mRNA levels, but rise much more rapidly. Regulation of translation suffices to explain this nonlinear effect, revealing post-transcriptional amplification of, rather than competition with, transcriptional signals. These results substantially revise widely credited models of protein-level regulation, and introduce multiple noise-aware approaches essential for proper analysis of many biological phenomena.
Predictors of Physicians' Attitudes Toward Sharing Information With Patients and Addressing Psychosocial Needs: A Cross-Sectional Study in Greece

Sharing information with patients and addressing their psychosocial needs are recognized as fundamental practices of patient-centered physicians. Our study explored predictors of physicians' patient-centered attitudes and yielded a better understanding of the relative influences of job satisfaction, employment status, specialty, previous communication skills training, and sociodemographic factors. Physicians who participated in 13 identical workshops offered throughout Greece were invited to complete a battery of anonymous questionnaires (demographics, job satisfaction scale, Patient–Practitioner Orientation Scale-Sharing subscale, and Physician Belief Scale). Prediction models were used to identify predictors of patient-centered attitudes. In total, 400 fully completed questionnaires were returned (response rate 79.8%). Job satisfaction, previous training in communication skills, younger age and lower socioeconomic status were predictors of positive attitudes toward sharing information with patients. Job satisfaction, previous training in communication skills, and stronger religious beliefs were predictors of higher psychosocial orientation. Job satisfaction and training in communication skills should be ensured in the effort to develop and maintain patient-centered attitudes in physicians. Religious beliefs, age, and socioeconomic status should be taken into consideration in the effort to help physicians become aware of their biases.
Androgen and Behavior in the Male Three-Spined Stickleback, Gasterosteus aculeatus
 II. Castration and 11-Ketoandrostenedione Effects on Courtship and Parental Care during the Nesting Cycle

Courtship declines and ceases while parental care increases in the presence of developing eggs during the nesting cycle of the male three-spined stickleback, Gasterosteus aculeatus. Furthermore, circulating 11-ketotestosterone (11KT) levels are higher during the initial "courtship phase" than during the later "parental phase," similar to that found in other paternal fishes. This study aimed to investigate a possible functional relationship between changes in 11KT levels and changes in reproductive behavior during the nesting cycle. To this end, groups of nonspawned and spawned male sticklebacks were sham-operated, castrated, or castrated and treated with 11-ketoandrostenedione (11KA), and the effects of the treatments on courtship and parental care were studied. Castration removed circulating 11KT, while 11KA replacement prevented the natural decline in 11KT during the parental phase (11KA converts to 11KT extratesticularly), as assessed by radioimmunoassay. Regardless of treatment, parental care remained low and courtship was present in all nonspawned males, even at the end of the experiment. However, courtship did eventually decline in castrated nonspawned males compared to the other two nonspawned groups. In all treatments of spawned males there was a drastic decline in courtship and an increase in parental care. In castrated spawned males, however, the decline in courtship came earlier than in the other two spawned groups. 11KA treatment did not prevent the natural decline in courtship/increase in parental care in spawned males, indicating that the natural decline in 11KT is not responsible for the main portion of the rapid changes in these behaviors over the stickleback's nesting cycle. The limited effects of castration also exclude other gonadal hormones from being responsible for most of these changes.
Stakeholder Perspectives on the Stigma of Suicide Attempt Survivors

Background: Past scholarly efforts to describe and measure the stigma surrounding suicide have largely viewed suicide stigma from the perspective of the general public. Aims: In the spirit of community-based participatory research (CBPR), the current study brought together a diverse stakeholder team to qualitatively investigate the suicide stigma as experienced by those most intimately affected by suicide. Method: Seven focus groups (n = 62) were conducted with suicide attempt survivors, family members of those who died by suicide, and suicide loss therapists. Results: Themes were derived for stereotypes (n = 30), prejudice (n = 3), and discrimination (n = 4). People who attempted suicide were seen as attention-seeking, selfish, incompetent, emotionally weak, and immoral. Participants described personal experiences of prejudice and discrimination, including those with health professionals. Conclusion: Participants experienced public stigma, self-stigma, and label avoidance. Analyses reveal that the stigma of suicide shares similarities with stereotypes of mental illness, but also includes some important differences. Attempt survivors may be subject to double stigma, which impedes recovery and access to care.
The method of hypersequents in the proof theory of propositional non-classical logics

Until not too many years ago, all logics except classical logic (and, perhaps, intuitionis-tic logic too) were considered to be things esoteric. Today this state of aaairs seems to have completely been changed. There is a growing interest in many types of nonclassical logics: modal and temporal logics, substructural logics, paraconsistent logics, non-monotonic logics { the list is long. The diversity of systems that have been proposed and studied is so great that a need is felt by many researchers to try to put some order in the present logical jungle. Thus Cl91], Ep90] and Wo88] are three recent books in which an attempt is made to develop a general theoretical framework for the study of logics. On the more pragmatic side, several systems have been developed with the goal of providing a computerized logical framework in which many diierent logical systems can be implemented in a uniform way. An example is the Edinburgh LF((HHP91]). It is clear that there is no limit to the number of logics that logicians (and non-logicians) can produce. Logical frameworks should only be expected, therefore, to be able to handle those that are \good" or \interesting". But what is a \good" logic? One simple answer might be: a logic which has applications. This answer is not satisfactory, though. First, systems of logics are frequently introduced before they nd actual applications. Moreover: there is a tendency to choose for application exactly those that are \good" in some sense. Second: Logic is an autonomous mathematical discipline, and as such 1
Musical Creativity and the Brain

Editor’s note: On the spot, as great jazz performers expertly improvise solo passages, they make immediate decisions about which musical phrases to invent and to play. Researchers, like authors Mónica López-González and Dana Foundation grantee Charles J. Limb, are now using brain imaging to study the neural underpinnings of spontaneous artistic creativity, from jazz riffs to freestyle rap. So far, they have found that brain areas deactivated during improvisation are also at rest during dreaming and meditation, while activated areas include those controlling language and sensorimotor skills. Even with relatively few completed studies, researchers have concluded that musical creativity clearly cannot be tied to just one brain area or process.
Turbo-Like Codes for Transmission of Correlated Sources over Noisy Channels

In this article we focus on distributed coding of correlated sources that are transmitted through either separated noisy channels (one per source) or over a multiple access channel (MAC). For simplicity, we consider only two sources, but the proposed approach can be easily extended to the case of more sources. The two sources are encoded independently of each other (i.e., for a given source neither the realization from the other source nor the correlation model are available at the encoder site) and transmitted through the channel. Then, the correlation between the sources is exploited at a common receiver, aiming at the reconstruction of the two sources. Although this problem has many practical applications e.g., in the case of sensor networks (where correlated data has to be communicated between the different nodes) and video/image applications, we will focus in the key ideas without discussing specific applications. For simplicity, we will assume simple correlation models and binary sources.
IMAGE WATERMARKING BASED DCT

Particle swarm optimization (PSO) is a new promising evolutionary algorithm for the optimization and search problem. One problem of PSO is its tendency to trap into local optima due to its mechanism in information sharing. This paper proposes a novel hybrid PSO, namely (HPSO) technique by merging both a mutation operator and natural selection to solve the problem of premature convergence. By introducing Cauchy mutation and evolutionary selection strategy based on roulette wheel selection, HPSO could greatly reduce the probability of trapping into local optimum. HPSO is proposed to improve the performance of fragile watermarking based DCT which results in enhancing both the quality of the watermarked image and the extracted watermark. After embedding watermark to the original image in the frequency domain, the conversion of real numbers of the modified coefficients in frequency domain to integer numbers in spatial domain produces some rounding errors problem. This problem results in completely different of the extracted watermark from the embedded watermark. The new developed PSO with evolutionary operators is carried out for correcting the rounding errors by training a translation map used to modify the inverse DCT (IDCT) coefficients from real to integer numbers. The experimental results show the superiority of the proposed algorithm comparing with the standard PSO for improving the performance of DCT fragile watermarking. Besides, it has been shown that the developed PSO is faster in convergence and the obtained results proved to have higher fitness than the other algorithm.