Miracle-dz/UniFAR-FTUs huggingface dataset:
Primary adrenal angiosarcoma and functioning adrenocortical adenoma: an exceptional combined tumor.

CONTEXT Primary adrenal angiosarcoma is an extremely rare neoplasm, as are combined tumors within a given adrenal lesion. CLINICAL PRESENTATION AND INTERVENTION A 35-year-old man presented with hypokalemic hypertension leading to the discovery of a 6 cm diameter malignant-appearing right adrenal tumor. The lesion displayed marked (18)F-fluorodeoxyglucose uptake on positron emission tomography scanning. Endocrine investigations revealed secretion of both cortisol and aldosterone by the neoplasm. The entire right adrenal gland along with the periadrenal fat tissue was removed during laparoscopic surgery. RESULTS Histological examination revealed two intermingled tumor cell proliferations, namely an angiosarcoma and an adrenocortical adenoma. An extensive post-operative search revealed no other primary tumor site, nor metastases. The lesion was then considered to be a primary adrenal angiosarcoma combined with a secreting adrenocortical adenoma. The patient received four cycles of chemotherapy (adriamycin/ifosfamide). At 2-year follow-up, he is alive and well, with no sign of relapse. CONCLUSION To the best of our knowledge, this is the first case of an adrenal neoplasm combining a primary angiosarcoma and a functioning adrenocortical adenoma.
Benefits of formal training courses within a professional services firm

Examines the effects of two aspects of formal training courses (participation, value) on both work setting characteristics and work outcomes. Data were collected from a large sample of managerial and professional women and men (n = 1,208) using questionnaires completed anonymously. All were employees of a single large professional services firm. About 90 per cent had participated in internal courses and about 40 per cent had participated in external courses in the last two years. Women and men participated at almost identical rates. The perceived value of formal training courses more than having participated in them was related to work setting characteristics and work outcomes, making allowances for personal demographic characteristics.
Full-Duplex Relaying With Improper Gaussian Signaling Over Nakagami- $m$ Fading Channels

We study the potential employment of improper Gaussian signaling (IGS) in full-duplex relaying (FDR) with non-negligible residual self-interference (RSI) under Nakagami- $m$ fading. IGS is recently shown to outperform traditional proper Gaussian signaling (PGS) in several interference-limited settings. In this paper, IGS is employed as an attempt to alleviate RSI. We use two performance metrics, namely, the outage probability and the ergodic rate. First, we provide upper and lower bounds for the system performance in terms of the relay transmit power and circularity coefficient, a measure of the signal impropriety. Then, we numerically optimize the relay signal parameters based only on the channel statistics to improve the system performance. Based on the analysis, IGS allows FDR to operate even with high RSI. The results show that IGS can leverage higher power budgets to enhance the performance, meanwhile it relieves RSI impact via tuning the signal impropriety. Interestingly, 1-D optimization of the circularity coefficient, with maximum relay power, offers a similar performance as the joint optimization, which reduces the optimization complexity. From a throughput standpoint, it is shown that IGS-FDR can outperform not only PGS-FDR, but also half-duplex relaying with/without maximum ratio combining over certain regions of the target source rate.
Collusion with denial: leadership development and its evaluation

Purpose – The purpose of this paper is to investigate ways to gain deeper understanding of the evaluation challenge by reporting on insights about the impact of a leadership development program. It focusses on participants’ reflective post-course analysis of their learning, comparing this to a traditional evaluative analysis. Recently there has been a greater focus on programs to develop leaders who have the requisite cognitive and behavioral complexity to lead in challenging environments. However models for the evaluation of such programs often rely on methodologies that assume learning of specific skills rather than assessment of how well participants are able to cognitively and behaviorally adapt to uncertain and complex environments. Design/methodology/approach – The leadership development program was evaluated in two stages and the findings compared. Stage 1 elicited responses to the program using a traditional evaluation approach. Stage 2 involved 30 semi-structured interviews with the participants .
What Do You Think Would Make You Happier? What Do You Think You Would Choose?

Would people choose what they think would maximize their subjective well-being (SWB)? We present survey respondents with hypothetical scenarios and elicit both choice and predicted SWB rankings of two alternatives. While choice and predicted SWB rankings usually coincide in our data, we find systematic reversals. We identify factors-such as predicted sense of purpose, control over one's life, family happiness, and social status-that help explain hypothetical choice controlling for predicted SWB. We explore how our findings vary by SWB measure and by scenario. Our results have implications regarding the use of SWB survey questions as a proxy for utility.
Evidence that heterogeneity of cerebral blood flow does not involve vascular recruitment.

Recent studies indicate that blood flow to cerebral cortex is not homogeneous but may vary both spatially and temporally. In addition, some investigators have reported that capillaries and arterioles can be recruited to increase cerebral blood flow, an issue that is extremely controversial. The goal of this study was to determine whether recruitment of cerebral blood vessels is an important mechanism in spatial and temporal heterogeneity of cerebral blood flow. In seven anesthetized ventilated rats, different fluorescent tracers were injected 45 and 10 s before decapitation. In addition, [14C]iodoantipyrine also was injected 10 s before decapitation. After the brains were sectioned, fields in the cerebral cortex were examined microscopically for fluorescence and processed for measurement of cerebral blood flow with techniques of quantitative autoradiography and image analysis. With examination of 24 +/- 2 (SE) points in cerebral cortex of each rat, similar numbers of small blood vessels (< or = 10 microns) were counted that contained fluorescent tracers injected 45 and 10 s before decapitation (346 +/- 48 and 355 +/- 42 vessels/mm2, respectively; P > 0.05). Large blood vessels (20-60 microns; 73 +/- 6 vessels in each rat) contained both fluorescent tracers. In addition, adjacent regions of high and low blood flow contained similar numbers of small and large vessels. Our findings indicate that vascular recruitment is not an important mechanism in temporal or spatial heterogeneity of cerebral blood flow.
Concurrent Determination of Brain Dopamine and 5‐Hydroxytryptamine Turnovers in Individual Freely Moving Rats Using Repeated Sampling of Cerebrospinal Fluid

Abstract: 5‐Hydroxytryptamine (5‐HT) turnover and dopamine (DA) turnover values were obtained in individual conscious rats by measuring the rates of accumulation of 5‐hydroxyindoleacetic acid (5‐HIAA), 3,4‐dihydroxy‐phenylacetic acid (DOPAC), and homovanillic acid (HVA) in cisternal CSF samples taken from each rat at 0, 30, and 60 min after probenecid (200 mg/kg i.p.) administration. In a separate experiment, 5‐HT and DA turnover values were determined in CSF, striatum, and rest of brain of groups of rats killed 0, 30, or 60 min after probenecid. Whole brain turnover values were calculated from striatal and rest of brain values. Mean turnover values using CSF were comparable with both procedures. DA turnover values were greater when based on total (i.e., free + conjugated) DA metabolites than when based on free metabolites. After partial inhibition of monoamine synthesis with the decarboxylase inhibitor DL‐α‐monofluoromethyl‐DOPA (MFMD, 100 mg/kg p.o.) DA and 5HT turnover values were comparably reduced in whole brain, rest of brain, and CSF but more markedly reduced in the striatum. Mean DA and 5‐HT turnover values obtained using CSF were similar with probenecid doses over the range 150‐250 mg/kg i.p. but were variable when repeatedly determined in the same rats after administration of 200 mg/kg probenecid. Results in general show that the CSF procedure may be used to determine concurrently both 5‐HT and DA turnover (when estimated from the sum of total but not free metabolites) and that it provides a good index of whole brain turnover of these transmitters in the conscious individual rat.
CD127low Expression in CD4+CD25high T Cells as Immune Biomarker of Renal Function in Transplant Patients

Background. Noninvasive tests measuring cellular immunity could help predict immunologic risk and subsequent allograft dysfunction in transplant patients. CD25 is a promising marker of activation. Recent descriptions of CD127 expression as a discriminating factor between regulatory and activated T cells suggest its potential utility. Methods. Expression of CD127 in CD4+CD25high T cells was analyzed by flow cytometry in peripheral blood from 62 renal transplanted patients and 30 healthy controls. Forty patients presented stable graft function and 22 suffered renal failure. Results. Renal transplant patients showed higher levels of CD127high and a lower frequency of CD127low than healthy controls (0.63% vs. 0.29% [P<0.001] and 1.4% vs. 2.4% [P<0.001], respectively). However, high frequencies of not only CD127high but also CD127low showed a significant correlation with serum creatinine levels (P=0.012 and P=0.003, respectively). Allogenic stimulation in vitro increased the frequency of CD127low subset in a dose dependent manner. Furthermore, in patients with a high frequency of CD127low subset, this consisted mostly of FoxP3 negative cells, discarding their regulatory origin. Median frequency of CD127low, but not CD127high, cells showed significant differences between patients with stable function and with renal failure (P<0.005), with 16.7% and 53.1% of individuals above the median CD127low value (1.4%), respectively. Conclusion. Quantification of CD127low subset through staining of CD4+ T cells with the combined markers CD127/CD25/CD45RO has been demonstrated to be a significant tool for monitoring the outcome course of renal transplant patients.
Constant mean curvature surfaces with Delaunay ends

In this paper we shall present a construction of complete surfaces M in R3 with finitely many ends and finite topology, and with nonzero constant mean curvature (CMC). This construction is parallel to the well-known original construction by Kapouleas [5], but we feel that ours is somewhat simpler analytically, and controls the resulting geometry more closely. On the other hand, the surfaces we construct have a rather different, and usually simpler, geometry than those of Kapouleas; in particular, all of the surfaces constructed here are noncompact, so we do not obtain any of his immersed compact examples. The method we use here closely parallels the one we developed recently [10] to study the very closely related problem of constructing Yamabe metrics on the sphere with k isolated singular points, just as Kapouleas’ construction parallels the earlier construction of singular Yamabe metrics by Schoen [18]. The original examples of noncompact CMC surfaces were those in the one-parameter family of rotationally invariant surfaces discovered by Delaunay in 1841 [2]. One extreme element of this family is the cylinder; the ‘Delaunay surfaces’ are periodic, and the embedded members of this family (which are called unduloids) interpolate between the cylinder and an infinite string of spheres arranged along a common axis. The family continues beyond this, but the elements now are immersed (and are called nodoids). The role of Delaunay surfaces in the theory of complete CMC surfaces is analogous to the role of catenoids (and planes) in the study of complete minimal surfaces of finite total curvature. For example, just as any complete minimal surface with two ends must be a catenoid [19], it was proved by Meeks [14] and Korevaar, Kusner and Solomon [8] that any Alexandrov embedded constant mean curvature surface with at most two ends is necessarily a Delaunay surface. A rather more remarkable theorem, paralleling the fact that any end of a complete minimal surface of finite total curvature must be asymptotic to a catenoid or a plane, is the fact that any embedded end of a CMC surface must be asymptotic to one of these rotationally symmetric Delaunay surfaces (and in particular, must be cylindrically bounded).
Temporal Contiguity and Negativity Bias in the Impact of Online Word of Mouth

Prior research shows that positive online reviews are less valued than negative reviews. The authors argue that this is due to differences in causal attributions for positive versus negative information such that positive reviews tend to be relatively more attributed to the reviewer (vs. product experience) than negative reviews. The presence of temporal contiguity cues, which indicate that review writing closely follows consumption, reduces the relative extent to which positive reviews are attributed to the reviewer and mitigates the negativity bias. An examination of 65,531 Yelp.com restaurant reviews shows that review value is negatively related to review valence but that this negative relationship is absent for reviews that contain temporal contiguity cues. A series of lab studies replicates these findings and suggests that temporal contiguity cues enhance the value of a positive review and increase the likelihood of choosing a product with a positive review by changing reader beliefs about the cause of the review.
Anxiety, Depression and Self-Esteem in Secondary School Children

With the introduction of a new curriculum and increased targets for schools, children are facing increased pressure to succeed in examinations at increasingly earlier ages. It is therefore necessary to emphasize the need for greater awareness of the distress that may be experienced by young children and adolescents as a result and implement provision for early interventions. The aim of this study was to investigate changes occurring in anxiety, affect, depression and self-esteem in secondary school children as they approached important school examinations and to examine variations between schools of differing design and status. There were a total of 520 participants, from four different schools in two school years (year 9, age 13-14 and year 11, age 15-16). Participants completed self-report questionnaires at two time points—firstly during regular term time and the second in the week immediately prior to the examinations. Gender differences were found in the majority of measures with females displaying greater levels of anxiety and negative affect immediately before the examinations, whereas males reported higher positive affect and self-esteem and lower depression and anxiety, even within the week prior to the examinations. Differences between the schools were also found. However, there were no significant differences between the two school years and the two times of testing. A number of trends were identified in relation to both gender differences and the influence of the type of school attended. Females, particularly those attending independent or grammar schools, reported a greater negative mood overall and before the examinations. It is suggested that there is a need for a school-based provision aimed at pro-actively increasing pupils self-esteem and to develop skills for dealing with stressful situations—particularly important examinations.
The social context of risk: Status and motivational predictors of alienation in middle school.

This study investigated the relations among 2 sociological predictors of risk for school leaving (race and social class), motivational context, and behavioral indicators of withdrawal from school in a sample of 405 7th grade students. Students completed questionnaires to assess their perceptions of the 3 aspects of their school motivational context, including the academic expectations and support of teachers and peers and the economic opportunity structure. Behavioral indicators of alienation were teachers' ratings of engagement and students' disciplinary problems. Students with more indicators of potential risk (i.e., low-income, African American, or both) were less engaged, had more disciplinary problems, and perceived their motivational contexts as more negative than students with fewer risk factors. Motivational context variables were stronger predictors of alienation than were status variables and partially mediated the relations between status indicators of potential risk and signs of alienation from school.
Ternary Neural Networks with Fine-Grained Quantization

We propose a novel fine-grained quantization (FGQ) method to ternarize pre-trained full precision models, while also constraining activations to 8 and 4-bits. Using this method, we demonstrate a minimal loss in classification accuracy on state-of-the-art topologies without additional training. We provide an improved theoretical formulation that forms the basis for a higher quality solution using FGQ. Our method involves ternarizing the original weight tensor in groups of $N$ weights. Using $N=4$, we achieve Top-1 accuracy within $3.7\%$ and $4.2\%$ of the baseline full precision result for Resnet-101 and Resnet-50 respectively, while eliminating $75\%$ of all multiplications. These results enable a full 8/4-bit inference pipeline, with best-reported accuracy using ternary weights on ImageNet dataset, with a potential of $9\times$ improvement in performance. Also, for smaller networks like AlexNet, FGQ achieves state-of-the-art results. We further study the impact of group size on both performance and accuracy. With a group size of $N=64$, we eliminate $\approx99\%$ of the multiplications; however, this introduces a noticeable drop in accuracy, which necessitates fine tuning the parameters at lower precision. We address this by fine-tuning Resnet-50 with 8-bit activations and ternary weights at $N=64$, improving the Top-1 accuracy to within $4\%$ of the full precision result with $<30\%$ additional training overhead. Our final quantized model can run on a full 8-bit compute pipeline using 2-bit weights and has the potential of up to $15\times$ improvement in performance compared to baseline full-precision models.
The Sociology of Professions and the Profession of Gender

Notwithstanding the growing numbers of women entering the professions and considerable public debate concerned with equal opportunity and barriers to women's advancement, attempts to theorise the relation between gender and profession within the discipline of sociology remain relatively rare. This paper draws on recent work on the gendering of organisation and bureaucracy to suggest that a key issue for consideration is not so much the exclusion of women from work defined as professional, but rather their routine inclusion in ill-defined support roles. This adjunct work of women, it is argued, facilitates the `fleeting encounter' of professional practice, thereby resting on, and celebrating, a specific historical and cultural construction of masculinity and a masculinist vision of professional work. In an era where professions are under unprecedented public scrutiny, sociological attention to their renewal needs to recognise that a key feature of profession, as presently defined, is that it professes gender.
Marriage In A Culture Of Divorce

Acknowledgments Introduction: Watershed in the Meaning of Marriage 1. Marriage and the Construction of Ideology: From Marriage Culture to Divorce Culture 2. The Shifting Grounds for Divorce: Structural and Cultural Conditions for Change 3. The Push of Marriage Culture Among '50s Spouses 4. The '50s Dominicks: Dominating with Divorce Culture 5. The '50s Hamptons and Other Couples: Redefining Marriage Culture in Terms of Gender Equality 6. '50s Spouses Secure Equal Footing in Divorce Culture 7. The '50s Era in Rearview Mirror 8. The Pull of Divorce Culture: Divorce Anxiety Among '70s Spouses 9. '70s Couples Aim for Relational Equality 10. The '70s Greens: Traditionalism in the 1990s 11. "Topsy-Turvy" Mariages Among '70s Spouses 12. Divorce Culture: A Quest for Relational Equality in Marriage Appendix: Methodological Notes Notes Bibliography Index
Obtaining presentations from group actions without making choices

Consider a group $G$ acting nicely on a simply-connected simplicial complex $X$. Numerous classical methods exist for using this group action to produce a presentation for $G$. For the case that $X/G$ is 2-connected, we give a new method that has the novelty that one does not have to identify a fundamental domain for the action. Indeed, the resulting presentation is canonical in the sense that no arbitrary choices need to be made. It can be viewed as a nonabelian analogue of a simple result in the study of equivariant homology.
Mechanisms of collective cell migration at a glance

This article is part of a Minifocus on collective cell migration. For further reading, please see related articles: `Wound repair at a glance' by Tanya Shaw and Paul Martin ( J. Cell Sci. 122 , [3209-3213][1]) and `Collective cell migration in development' by Cornelis Weijer ( J. Cell Sci. 122 , [
Effects of Tiered Training on General Educators' Use of Specific Praise

Research suggests a compelling correlation between teacher behavior and effective learning environments. Focusing on the evidence-based teaching skill of offering behavior-specific praise (BSP), the researchers worked with three elementary-level general educators in a tiered model of training generally known as response to intervention (RtI). Although RtI commonly provides targeted instructional support to students, this study used the RtI framework to provide professional development instruction to teachers. The researchers also tracked the behavior of three students identified by the teachers as having behavioral difficulties, who became the focus of each teacher's BSP. Results showed increases in rates of BSP following the Tier 2 and Tier 3 interventions (video self-monitoring and peer coaching), but not following the Tier 1 intervention (school-wide in-service training). Averages for all three students' on-task behavior increased with increased teacher BSP.
Analysis and Design of the Classical CMOS Schmitt Trigger in Subthreshold Operation

In this paper, the classical CMOS Schmitt trigger (ST) operating in the subthreshold regime is analyzed. The complete DC voltage transfer characteristic of the CMOS ST is determined. The metastable segment of the characteristic is explained in terms of the negative resistance of the NMOS and PMOS subcircuits of the ST. Small-signal analysis is carried out to determine the minimum supply voltage at which the hysteresis appears and to obtain a rough estimation of the hysteresis width. It is shown that the theoretical minimum supply voltage required to obtain hysteresis is 2ln( $2+\surd 5$ )kT/q = 75 mV at room temperature. A test chip with CMOS Schmitt triggers was designed and fabricated in a 180 nm technology in order to study their operation at supply voltages between 50 mV and 1000 mV.