Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of Organizations Resources on Performance for Digital Content Industry

A company could grow up steadily and create different values if it makes use of resource efficiently. In the growing process of the digital content industry, using resources efficiently and investing innovation activities are the essential factors in operation performance, R&D performance, and human performance. We build the research framework based on the resource-based theory in accordance with innovative technology and human resource, and explore the effect of resources on the performances about sustained advantage. The paper adopts the method of case study to investigate current situations about the relationship between resource features and performance in digital content industry. The result shows six propositions. (1) An organization with valuable, rare, and imperfectly imitable product upgrade could be superior operation performance. (2) An organization with valuable, rare, and imperfectly imitable IP rights could be superior operation performance. (3) An organization with valuable and rare disruptive innovation could be superior R&D performance. (4) An organization with valuable, rare, imperfectly imitable, and non-substitute R&D input could be superior R&D performance. (5) The staff of an organization with valuable and imperfectly imitable skill could be superior human performance. (6) The staff of an organization with valuable, rare, imperfectly imitable knowledge could be superior human performance.
Transcriptome characterization of Pocillopora grandis transplanted into reefs with different health conditions: potential stress indicators at the holobiont level

Understanding the potential of coral to adapt to environmental stressors that cause coral bleaching is urgent. The molecular responses of the coral holobiont to such stress conditions determine the success of symbiosis. Therefore, by characterizing molecular stress responses at the holobiont level, we can develop better tools to diagnose its health and resilience. However, only some genomic-scale resources are available for reefbuilding corals from the Eastern Tropical Pacific. This study aimed to perform a transcriptomic characterization of the Pocillopora grandis holobiont following transplantation into environments with different health conditions in Colima, Mexico. Healthy specimens of two color morphotypes (green and brown) were collected in Carrizales, a reef in good condition. Coral fragments from the two morphotypes were relocated within the source location (local transplant stress). In contrast, similar fragments were translocated into another reef with a poorer health state, La Boquita. After 24 h, the transplanted fragments were collected, and RNA-seq was performed with the Illumina system. De novo transcriptome assembly, functional annotation, identification of co-expression modules, and enrichment analysis of molecular pathways were performed. The analysis of rRNA LSU, rRNA SSU, and COI sequences confirmed the coral species, whereas analysis of Rubisco, psbA, and psaA transcripts revealed that the dominant endosymbiont was Durusdinium sp. Gene expression patterns observed across samples suggest that the transplantation to a reef with a poorer state of health affected processes such as photosynthesis, calcium homeostasis, and immune response. The transcriptomic indicators proposed here are valuable for further studies examining the adaptation of Pocillopora corals to global changes.
Novel Phylogenetic Algorithm to Monitor Human Tropism in Egyptian H5N1-HPAIV Reveals Evolution toward Efficient Human-to-Human Transmission

Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential. In an effort to better understand the viral determinants that facilitate human infections of the Egyptian H5N1-HPAIVvirus, we developed a new phylogenetic algorithm based on a new distance measure derived from the informational spectrum method (ISM). This new approach, which describes functional aspects of the evolution of the hemagglutinin subunit 1 (HA1), revealed a growing group G2 of H5N1-HPAIV in Egypt after 2009 that acquired new informational spectrum (IS) properties suggestive of an increased human tropism and pandemic potential. While in 2006 all viruses in Egypt belonged to the G1 group, by 2011 these viruses were virtually replaced by G2 viruses. All of the G2 viruses displayed four characteristic mutations (D43N, S120(D,N), (S,L)129Δ and I151T), three of which were previously reported to increase binding to the human receptor. Already in 2006–2008 G2 viruses were significantly (p<0.02) more often found in humans than expected from their overall prevalence and this further increased in 2009–2011 (p<0.007). Our approach also identified viruses that acquired additional mutations that we predict to further enhance their human tropism. The extensive evolution of Egyptian H5N1-HPAIV towards a preferential human tropism underlines an urgent need to closely monitor these viruses with respect to molecular determinants of virulence.
Laryngeal Mask Airway Positioning Is Related to Mallampati Grading in Adults

The Mallampati classification is a commonly used means of preoperatively predicting a difficult endotracheal intubation.As the laryngeal portion of the laryngeal mask airway (LMA) must sit over the larynx, we wondered whether the Mallampati classification also predicts difficulty in achieving adequate seating of the LMA. LMA positioning was assessed prospectively in 100 adult patients by fiberoptic bronchoscopy to determine whether there was a relationship between the ease of seating of the LMA and the Mallampati classification. In 72 patients, optimal seating of the LMA was achieved on the first attempt at insertion, and all these patients were classified as Mallampati class 1 or 2. In all 28 cases of difficulty with LMA insertion, the patients were Mallampati class 2 or 3. In two cases the LMA was abandoned, and in these cases both patients were Mallampati class 3, (P = 0.0001 by chi squared analysis). We conclude that the Mallampati classification indicates difficulty not only in tracheal intubation but also in achieving an adequate airway with the LMA. (Anesth Analg 1995;81:1001-4)
Optimal correlating transform for erasure channels

In this letter, we derive a gradient-based algorithm for computing the optimal transform when coefficients are transmitted over an erasure channel whose statistics are known. The discrete transform introduces correlation among the coefficients with consequent performance improvement against losses. Simulations show appreciable improvements over standard schemes and also good robustness when loss probabilities are only roughly estimated.
A high signal-to-noise ratio map of the Sunyaev–Zel’dovich increment at 1.1-mm wavelength in Abell 1835

We present an analysis of an 8-arcmin diameter map of the area around the galaxy cluster Abell 1835 from jiggle-map observations at a wavelength of 1.1 mm using the Bolometric Camera (Bolocam) mounted on the Caltech Submillimeter Observatory (CSO). The data are well described by a model including a extended Sunyaev–Zel’dovich (SZ) emission from the cluster gas plus emission from the cluster central galaxy and two bright background submm galaxies magnified by the gravitational lensing of the cluster. We measure flux densities of the two bright point sources in the field: SMM J14011+0252 and SMM J14009+0252 to be 6.5 ± 2.0 ± 0.8 and 11.3 ± 1.9 ± 1.3 mJy, respectively. Fitting the map to a sky model consisting of the point sources and the SZ emission from the cluster gas with a beta model density profile with parameters, θ_c= 33.6 arcsec and β= 0.69, we find the peak surface brightness of the SZ emission to be I_c= 3.73 ± 0.45 ± 0.60 × 10^(−21) W m^(−2)sr^(−1) Hz^(−1), where the first error is the statistical uncertainty in the fit and the second error represents the calibration uncertainty and additional systematics. Assuming zero cluster peculiar velocity and an X-ray temperature of T_e= 9 keV, this surface brightness corresponds to a central Comptonization of y_0= (4.41 ± 0.53 ± 0.70) × 10^(−4). The cluster image represents one of the highest significance SZ detections of a cluster in the positive region of the thermal SZ spectrum to date. We compare the measured central intensity at 1.1 mm to other SZ measurements of Abell 1835 at different wavelengths to obtain values for y_0= (3.58 ± 0.28) × 10^(−4) and the cluster peculiar velocity v_z=−538 ± 414 km s^(−1).
Quantitative analysis of K-ras gene mutation in pancreatic tissue obtained by endoscopic ultrasonography-guided fine needle aspiration: clinical utility for diagnosis of pancreatic tumor

OBJECTIVES:Endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) has become established in the diagnosis of pancreatic cancer. The combination of pathological diagnosis and analysis for mutant K-ras gene was investigated to improve the accuracy of diagnosis.METHODS:EUS-FNA was performed in 34 patients with pancreatic masses (26 adenocarcinomas and eight chronic pancreatitis). Mutant ras gene was analyzed semiquantitatively in the specimens obtained by EUS-FNA as well as in pancreatic juice obtained by ERCP.RESULTS:Mutant gene was detected at high amounts (more than 2% of total ras genes) in 20 of 26 (77%) specimens of EUS-FNA and in 12 of 19 (63%) of pancreatic juice in cases with pancreatic carcinoma. Cytological diagnosis of malignancy by EUS-FNA was found in 16 of 26 (62%) patients with pancreatic cancer. Accurate diagnosis of the carcinoma was 21 of 26 (81%) by combined cytology and molecular method of EUS-FNA, and increased to 23 of 26 (88%) by adding molecular analysis of pancreatic juice. In contrast, mutant gene was absent or low level despite suspicious cytology in patients with benign pancreatic lesion.CONCLUSION:Quantitative analysis of mutant ras gene supplemented conventional cytology of EUS-FNA and ERCP. Detection of mutation at high amounts may represent pancreatic cancer, whereas its absence increased the possibility of benign lesion.
Thermal Properties and Drying Shrinkage Performance of Palm Kernel Shell Ash and Rice Husk Ash-Based Geopolymer Concrete

This study aims to develop suitable formulations of geopolymer concrete (GPC) by varying the percentages of the geopolymer with aggregates and evaluating the performances in thermal and mechanical properties of palm kernel shell ash (PKSA)-GPC compared to rice husk ash (RHA)-GPC and ordinary Portland cement concrete (OPCC). Preliminary tests were conducted to select the best mix design ratios before casting the specimens. Then, the performance of the PKSA-GPC, RHA-GPC and OPCC specimens was evaluated based on their thermal performance and drying shrinkage. The mix designs of PKSA-GPC 70:30, PKSA-GPC 60:40, PKSA-GPC 50:50 and PKSA-GPC 66.6:33.3 were found to produce an acceptable consistency, rheological and thixotropic behaviour for the development of the GPC. PKSA-GPC showed a better thermal performance than the RHA-GPC and OPCC due to their strong and dense intumescent layers and slow temperature increment upon exposure to a high flame temperature from ambient temperature to 169 °C. The low molar ratio of the Si/Al present in the PKSA-GPC created a thermally stable intumescent layer. In the drying shrinkage test, PKSA-GPC 60:40 and RHA-GPC 60:40 shared an equal drying shrinkage performance (5.040%) compared to the OPCC (8.996%). It was observed that microcrack formation could significantly contribute to the high shrinkage in the PKSA-GPC 50:50 and RHA-GPC 70:30 specimens. The findings of this study show that PKSA could be incorporated into GPC as a fire-retardant material due to its capability of prolonging the spread of fire upon ignition and acting as an alternative to the conventional OPCC.
Effects of a Randomized Intervention to Improve Workplace Social Capital in Community Health Centers in China

Objective To examine whether workplace social capital improved after implementing a workplace social capital intervention in community health centers in China. Methods This study was conducted in 20 community health centers of similar size in Jinan of China during 2012–2013. Using the stratified site randomization, 10 centers were randomized into the intervention group; one center was excluded due to leadership change in final analyses. The baseline survey including 447 staff (response rate: 93.1%) was conducted in 2012, and followed by a six-month workplace social capital intervention, including team building courses for directors of community health centers, voluntarily public services, group psychological consultation, and outdoor training. The follow-up survey in July 2013 was responded to by 390 staff members (response rate: 86.9%). Workplace social capital was assessed with the translated and culturally adapted scale, divided into vertical and horizontal dimensions. The facility-level intervention effects were based on all baseline (n = 427) and follow-up (n = 377) respondents, except for Weibei respondents. We conducted a bivariate Difference-in-Difference analysis to estimate the facility-level intervention effects. Results No statistically significant intervention effects were observed at the center level; the intervention increased the facility-level workplace social capital, and its horizontal and vertical dimensions by 1.0 (p = 0.24), 0.4 (p = 0.46) and 0.8 (p = 0.16), respectively. Conclusions The comprehensive intervention seemed to slightly improve workplace social capital in community health centers of urban China at the center level. High attrition rate limits any causal interpretation of the results. Further studies are warranted to test these findings.
Infinite Latent Harmonic Allocation: A Nonparametric Bayesian Approach to Multipitch Analysis

This paper presents a statistical method called Infinite Latent Harmonic Allocation (iLHA) for detecting multiple fundamentalfrequenciesin polyphonicaudiosignals. Conventional methods face a crucial problem known as model selection becausetheyassume thatthe observedspectra are superpositions of a certain fixed number of bases (sound sources and/or finer parts). iLHA avoids this problem by assuming that the observed spectra are superpositions of a stochastically-distributed unbounded (theoretically infinite) number of bases. Such uncertainty can be treated in a principled way by leveraging the state-of-the-art paradigm of machine-learning called Bayesian nonparametrics. To represent a set of time-sliced spectral strips, we formulated nested infinite Gaussian mixture models (GMMs) based on hierarchical and generalized Dirichlet processes. Each strip is allowed to contain an unbounded number of sound sources (GMMs), each of which is allowed to contain an unbounded number of harmonic partials (Gaussians). To train the nested infinite GMMs efficiently, we used a modern inference technique called collapsed variational Bayes (CVB). Our experiments using audio recordingsof real piano and guitar performances showed that fully automated iLHA based on noninformativepriorsperformedas well as optimally tuned conventional methods.
Ain't necessarily so: review and critique of recent meta-analyses of behavioral medicine interventions in health psychology.

OBJECTIVE We examined four meta-analyses of behavioral interventions for adults (Dixon, Keefe, Scipio, Perri, & Abernethy, 2007; Hoffman, Papas, Chatkoff, & Kerns, 2007; Irwin, Cole, & Nicassio, 2006; and Jacobsen, Donovan, Vadaparampil, & Small, 2007) that have appeared in the Evidence Based Treatment Reviews section of Health Psychology. DESIGN Narrative review. MAIN OUTCOME MEASURES We applied the following criteria to each meta-analysis: (1) whether each meta-analysis was described accurately, adequately, and transparently in the article; (2) whether there was an adequate attempt to deal with methodological quality of the original trials; (3) the extent to which the meta-analysis depended on small, underpowered studies; and (4) the extent to which the meta-analysis provided valid and useful evidence-based recommendations. RESULTS Across the four meta-analyses, we identified substantial problems with the transparency and completeness with which these meta-analyses were reported, as well as a dependence on small, underpowered trials of generally poor quality. CONCLUSION Results of our exercise raise questions about the clinical validity and utility of the conclusions of these meta-analyses. Results should serve as a wake up call to prospective authors, reviewers, and end-users of meta-analyses now appearing in the literature.
Bioinformatics analysis of experimentally determined protein complexes in the yeast, S. cerevisiae

Many important cellular functions are implemented by protein complexes that act as sophisticated molecular machines of varying size and temporal stability. Here we demonstrate quantitatively that protein complexes in the yeast, Saccharomyces cerevisiae, are comprised of a core in which subunits are highly coexpressed, display the same deletion phenotype (essential or non-essential) and share identical functional classification and cellular localization. This core is surrounded by a functionally mixed group of proteins, which likely represent short-lived- or spurious attachments. The results allow us to define the deletion phenotype and cellular task of most known complexes, and to identify with high confidence the biochemical role of hundreds of proteins with yet unassigned functionality.
Personal health records

Personal health record (PHR) systems are a subject of intense interest in the move to improve healthcare accessibility and quality. Although a number of vendors continue to put forward PHR systems, user-centered design research has lagged, and it has not been clear what features are important to prospective PHR users. Here, we report on a user-centered design study that combines qualitative and quantitative approaches to investigate several dimensions relevant to PHR design, and to look at the effect of health status on user needs. The results indicate that health status, especially disability and chronic illness, is relevant to PHR design. Further, the results provide empirical evidence about the role of privacy and security in users’ attitudes toward PHR use. The exact nature of these attitudes differs from widely held perceptions about consumer values in healthcare information management.
Threshold Bandit, With and Without Censored Feedback

We consider the Threshold Bandit setting, a variant of the classical multi-armed bandit problem in which the reward on each round depends on a piece of side information known as a threshold value . The learner selects one of K actions (arms), this action generates a random sample from a ﬁxed distribution, and the action then receives a unit payoff in the event that this sample exceeds the threshold value. We consider two versions of this problem, the uncensored and censored case, that determine whether the sample is always observed or only when the threshold is not met. Using new tools to understand the popular UCB algorithm, we show that the uncensored case is essentially no more difﬁcult than the classical multi-armed bandit setting. Finally we show that the censored case exhibits more challenges, but we give guarantees in the event that the sequence of threshold values is generated optimistically.
The upregulation of heat shock protein 47 expression in human buccal fibroblasts stimulated with arecoline.

BACKGROUND Heat shock protein (HSP) 47, a collagen-specific molecular chaperone, is involved in the processing and/or secretion of procollagen. HSP47 is consistently and dramatically upregulated in a variety of fibrotic diseases. The aim of this study was to compare HSP47 expression in normal human buccal mucosa and oral submucous fibrosis (OSF) specimens and further to explore the potential mechanisms that may lead to induce HSP47 expression. METHODS The mRNA levels of HSP47 from fibroblasts cultured from 20 OSF and 10 normal buccal mucosal fibroblasts (BMFs) were evaluated by reverse transcription polymerase chain reaction. The effect of arecoline, the major areca nut alkaloid, was added to explore the potential mechanisms that may lead to induce HSP47 expression. Furthermore, mitogen-activated protein kinase kinase (MEK) inhibitor U0126, phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002, p38 inhibitor SB203580, cyclo-oxygenase-2 (COX-2) inhibitor NS-398, and glutathione precursor N-acetyl-l-cysteine were added to find the possible mechanisms. RESULTS OSF demonstrated significantly higher HSP47 mRNA expression than BMFs (P < 0.001). Arecoline was also found to elevate HSP47 mRNA expression in a dose-dependent manner (P < 0.05). The amount of HSP47 was about 3.7-fold at a concentration level of 80 microg/ml arecoline when compared with control (P < 0.05). In addition, pre-treatment with pharmacologic agents markedly inhibited the arecoline-induced HSP47 mRNA expression (P < 0.05). CONCLUSIONS Taken together, HSP47 is significantly upregulated in OSF from areca quid chewers and HSP47 expression induced by arecoline in fibroblasts may be mediated by MEK, PI3K, and COX-2 signal transduction pathways.
Economic Gardening in Australia: measuring attitudes towards growth

In 2006 University of Wollongong researchers were invited to participate in an Economic Gardening project being implemented in the New South Wales local government areas of Shellharbour and Kiama. This paper outlines the history of the “economic gardening” concept and the challenges for participant selection and training. We propose an alterative approach to that undertaken by previous economic gardening proponents based on a direct measure of attitudes towards employment growth. A new methodological approach is presented which aims to derive more reliable predictors of participant selection for future economic gardening projects.
Helicobacter pylori in Colorectal Carcinoma Tissue

Helicobacter pylori ([1][1]) is associated with the development of chronic gastritis, peptic ulcer, and gastric adenocarcinoma ([2][2]-[4][3]). Previous studies reported positive ([5][4], [6][5]) and negative ([7][6], [8][7]) associations between infection and colorectal neoplasia. Recent reports
Different bifurcation Scenarios of Neural Firing Patterns observed in the Biological Experiment on identical pacemakers

Two different bifurcation scenarios of spontaneous neural firing patterns with decreasing extracellular calcium concentrations were observed in the biological experiment on identical pacemakers when potassium concentrations were fixed at two different levels. Six typical experimental scenarios manifesting dynamics closely matching those previously simulated using the Hindmarsh–Rose model and Chay model are provided as representative examples. Bifurcation scenarios from period-1 bursting to period-1 spiking via a complex process and via a simple process, period-doubling bifurcation to chaos, period-adding bifurcation with chaos, and period-adding bifurcation with stochastic burstings were identified. The results not only reveal that an experimental neural pacemaker is capable of generating different bifurcation scenarios but also provide a basic framework for bifurcations in neural firing patterns in a two-dimensional parameter space.