Miracle-dz/UniFAR-FTUs huggingface dataset:
Stress, Coping, and Emotions on the World Stage: The Experience of Participating in a Major Soccer Tournament Penalty Shootout

This study was designed to capture the first-hand experiences of stressors, coping, and emotions that elite professional soccer players have during a major soccer penalty shootout. Eight players who each took part in an important European Championships penalty shootout were interviewed. The results showed that the experience of stressors, coping, and emotions changed extensively throughout the event. Moreover, the participants experienced a series of different stressors, some of which were specific to the penalty shootout, and they employed a variety of coping strategies. Anxiety was the most common emotion. Practitioners can use these results to help design valid simulation protocols.
Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatids

Meiotic recombination initiates via programmed double-strand breaks (DSBs). We investigate whether, at a given initiation site, DSBs occur independently among the four available chromatids. For a single DSB “hot spot”, the proportions of nuclei exhibiting zero, one, or two (or more) observable events were defined by tetrad analysis and compared with those predicted by different DSB distribution scenarios. Wild-type patterns are incompatible with independent distribution of DSBs among the four chromatids. In most or all nuclei, DSBs occur one-per-pair of chromatids, presumptively sisters. In many nuclei, only one DSB occurs per four chromatids, confirming the existence of trans inhibition where a DSB on one chromosome interactively inhibits DSB formation on the partner chromosome. Several mutants exhibit only a one-per-pair constraint, a phenotype we propose to imply loss of trans inhibition. Signal transduction kinases Mec1 (ATR) and Tel1 (ATM) exhibit this phenotype and thus could be mediators of this effect. Spreading trans inhibition can explain even spacing of total recombinational interactions and implies that establishment of interhomolog interactions and DSB formation are homeostatic processes. The two types of constraints on DSB formation provide two different safeguards against recombination failure during meiosis.
Extended use of dabigatran, warfarin, or placebo in venous thromboembolism.

BACKGROUND Dabigatran, which is administered in a fixed dose and does not require laboratory monitoring, may be suitable for extended treatment of venous thromboembolism. METHODS In two double-blind, randomized trials, we compared dabigatran at a dose of 150 mg twice daily with warfarin (active-control study) or with placebo (placebo-control study) in patients with venous thromboembolism who had completed at least 3 initial months of therapy. RESULTS In the active-control study, recurrent venous thromboembolism occurred in 26 of 1430 patients in the dabigatran group (1.8%) and 18 of 1426 patients in the warfarin group (1.3%) (hazard ratio with dabigatran, 1.44; 95% confidence interval [CI], 0.78 to 2.64; P=0.01 for noninferiority). Major bleeding occurred in 13 patients in the dabigatran group (0.9%) and 25 patients in the warfarin group (1.8%) (hazard ratio, 0.52; 95% CI, 0.27 to 1.02). Major or clinically relevant bleeding was less frequent with dabigatran (hazard ratio, 0.54; 95% CI, 0.41 to 0.71). Acute coronary syndromes occurred in 13 patients in the dabigatran group (0.9%) and 3 patients in the warfarin group (0.2%) (P=0.02). In the placebo-control study, recurrent venous thromboembolism occurred in 3 of 681 patients in the dabigatran group (0.4%) and 37 of 662 patients in the placebo group (5.6%) (hazard ratio, 0.08; 95% CI, 0.02 to 0.25; P<0.001). Major bleeding occurred in 2 patients in the dabigatran group (0.3%) and 0 patients in the placebo group. Major or clinically relevant bleeding occurred in 36 patients in the dabigatran group (5.3%) and 12 patients in the placebo group (1.8%) (hazard ratio, 2.92; 95% CI, 1.52 to 5.60). Acute coronary syndromes occurred in 1 patient each in the dabigatran and placebo groups. CONCLUSIONS Dabigatran was effective in the extended treatment of venous thromboembolism and carried a lower risk of major or clinically relevant bleeding than warfarin but a higher risk than placebo. (Funded by Boehringer Ingelheim; RE-MEDY and RE-SONATE ClinicalTrials.gov numbers, NCT00329238 and NCT00558259, respectively.).
Controllable synthesis of flower- and rod-like ZnO nanostructures by simply tuning the ratio of sodium hydroxide to zinc acetate

A controlled synthesis of flower- and rod-like ZnO nanostructures in a hydrothermal phase has been realized in the absence of an additional template. The well-defined morphologies are obtained by simply tuning the ratio of sodium hydroxide to zinc acetate in a narrow range. The products are characterized by powder x-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The growth mechanism is suggested to be that the supersaturation of the precursor Zn(OH)42− results in various nucleation habits, which induce the ZnO nanostructures with different morphologies.
Young Musicians' Accounts of Significant Influences in their Early Lives. 1. The Family and the Musical Background

This article reports qualitative findings of an interview study in which 42 students (aged 10–18) from a specialist music school were encouraged to talk about various experiences in their lives which the individual children perceived as having been potentially significant influences on their progress in learning musical instruments. The parents of half the children were also interviewed. Observations concerning the following sources of influence are reported: the family background; sibling influences; listening to music. The insights of children and their parents, which complement and add depth to quantitative findings concerning the biographical precursors of musical excellence, help to provide a rich source of descriptive information about the circumstances in which children become competent young musicians.
The Communicative Development Inventory-WORDS Short Form as an index of language production

ABSTRACT This longitudinal study was designed to examine the CDI-WORDS Short Form vocabulary checklist (Reznick & Goldsmith, 1989) as an index of language production. In particular, we were curious about: (1) the concurrent associations between the CDI-WORDS Short Form checklist measure and directly observed measures of lexical production; (2) the associations between Short Form checklists administered at different ages; and (3) the predictive associations between Short Form scores and subsequent measures of more general intellectual abilities (i.e. the Wechlser Preschool and Primary Scale of Intelligence; WPPSIR; Wechsler, 1989). In a sample of 32 children, significant correlations were found between CDI-WORDS Short Form scores and directly observed measures of lexical production at both 1;6 and 2;0. Further, both the Short Form checklist and the observed measure of lexical production were found to predict WPPSI-R Verbal IQ scores but not the Performance IQ scores at 4;0. Additional analyses demonstrated the predictive and convergent validity of the CDI-WORDS Short Form, and underscored the additional value of direct observational measures of lexical production during early lexical development.
Clozapine, Olanzapine, Risperidone, and Haloperidol in the Treatment of Patients With Chronic Schizophrenia and Schizoaffective Disorder

OBJECTIVE: The authors compared the efficacy and safety of three atypical antipsychotics (clozapine, olanzapine, and risperidone) with one another and with haloperidol in the treatment of patients with chronic schizophrenia or schizoaffective disorder. METHOD: In a double-blind trial, 157 inpatients with a history of suboptimal treatment response were randomly assigned to treatment with clozapine, olanzapine, risperidone, or haloperidol for 14 weeks (an 8-week escalation and fixed-dose period followed by a 6-week variable-dose period). RESULTS: Clozapine, risperidone, and olanzapine (but not haloperidol) resulted in statistically significant improvements in total score on the Positive and Negative Syndrome Scale. Improvements seen in total and negative symptom scores with clozapine and olanzapine were superior to haloperidol. The atypical drugs, particularly olanzapine and clozapine, were associated with weight gain. CONCLUSIONS: The effects of atypical antipsychotics in this population were statistically.
Statically balanced direct drive manipulator

SUMMARY A practical architecture, using a four-bar-linkage, is considered for the University of Minnesota direct drive rotot. This statically-balanced direct drive robot has been constructed for stability analysis of the robot in constrained maneuvers.2–6 As a result of the elimination of the gravity forces (without any counter weights), smaller actuators and consequently smaller amplifiers were chosen. The motors yield acceleration of 5 g at the robot end point without overheating. High torque, low speed, brush-less AC synchronous motors are used to power the robot. Graphite-epoxy composite material is used for the construction of the robot links. A 4-node parallel processor has been used to control the robot. The dynamic tracking accuracy-with the feedforward torque method as a control law- has been derived experimentally.
Iatrogenic Cushing's syndrome and topical steroid therapy: case series and review of the literature

Topical corticosteroids are considered first-line therapy in patients with chronic inflammatory oral mucosal diseases; among them, clobetasol propionate is one of the most widely used in oral medicine. Under physiological conditions, the transmucosal application is characterized by a significantly greater absorption than the skin application. Contrary to many publications about the side effects of topical corticosteroids in dermatology, few studies have investigated the systemic effects due to local application of these drugs on oral mucosa. Although topical steroid therapy for the management of oral diseases is generally associated with local adverse effects (candidiasis, stomatopyrosis, and hypogeusia), these drugs can also lead to systemic side effects, such as suppression of the hypothalamic-pituitary-adrenal axis and Cushing's syndrome. This review reports five cases of systemic adverse effects caused by clobetasol propionate topical treatment.
Stakeholder inclusivity in social and environmental report assurance

Purpose - The purpose of the research was to discover the process of social and environmental report assurance (SERA) and thereby evaluate the benefits, extent of stakeholder inclusivity and/or managerial capture of SERA processes and the dynamics of SERA as it matures. Design/methodology/approach - This paper used semi-structured interviews with 20 accountant and consultant assurors to derive data, which were then coded and analysed, resulting in the identification of four themes. Findings - This paper provides interview evidence on the process of SERA, suggesting that, although there is still managerial capture of SERA, stakeholders are being increasingly included in the process as it matures. SERA is beginning to provide dual-pronged benefits, adding value to management and stakeholders simultaneously. Through the lens of Freirian dialogic theory, it is found that SERA is starting to display some characteristics of a dialogical process, being stakeholder inclusive, demythologising and transformative, with assurors perceiving themselves as a “voice” for stakeholders. Consequently, SERA is becoming an important mechanism for driving forward more stakeholder-inclusive SER, with the SERA process beginning to transform attitudes of management towards their stakeholders through more stakeholder-led SER. However, there remain significant obstacles to dialogic SERA. The paper suggests these could be removed through educative and transformative processes driven by assurors. Originality/value - Previous work on SERA has involved predominantly content-based analysis on assurance statements. However, this paper investigates the details of the SERA process, for the first time using qualitative interview data.
Cell Phone Decision Making

The primary aim of this study was to examine how and why adolescents make decisions regarding whether to conduct their communication via texting versus calling features of cellular telephones. Individual semistructured qualitative interviews were conducted with 41 adolescents aged 14 to 18 focusing on their use of calling and texting when communicating with friends, parents, and romantic partners. Through grounded theory analysis, a conceptual decision-tree emerged depicting a process of decision making based on communication content, communication partner, and situational limitations. Further analysis indicated that the adolescents consistently perceived texting as easier than calling in ways that were meaningful to their everyday lives. Findings reflect the complex interweaving of logic, personal preference, and concession to social constraints that goes into adolescents’ choices to call versus text.
Working in music: Becoming a performer-teacher

Performer-teachers are defined here as performers for whom instrumental teaching is integral to their professional identity. This study explores the careers of performer-teachers who are alumni of a UK conservatoire. Performer-teachers emerge as focused 'career performers' who fall among those experts known as 'accomplished novices', rather than 'answer-filled experts. ' Their enthusiasm for learning broadly reflects their belief that teaching informs their performing, and helps to explain why teaching is integral to their professional identity. Students who aspire to become professors could model themselves on their teachers: by ensuring that their repertoire remains broad and by drawing lessons about performing from activities including teaching.
Neural Processing in the Subsecond Time Range in the Temporal Cortex

The hypothesis that cortical processing of the millisecond time range is performed by latency competition between the first spikes produced by neuronal populations is analyzed. First, theorems that describe how the mechanism of latency competition works in a model cortex are presented. The model is a sequence of cortical areas, each of which is an array of neuronal populations that laterally inhibit each other. Model neurons are integrate-and-fire neurons. Second, the model is applied to the ventral pathway of the temporal lobe, and neuronal activity of the superior temporal sulcus of the monkey is reproduced with the model pathway. It consists of seven areas: V1, V2/V3, V4, PIT, CIT, AIT, and STPa. Neural activity predicted with the model is compared with empirical data. There are four main results: (1) Neural responses of the area STPa of the model showed the same fast discrimination between stimuli that the corresponding responses of the monkey did: both were significant within 5 ms of the response onset. (2) The hypothesis requires that the response latency of cortical neurons should be shorter for stronger responses. This requirement was verified by both the model simulation and the empirical data. (3) The model reproduced fast discrimination even when spontaneous random firing of 9 Hz was introduced to all the cells. This suggests that the latency competition performed by neuronal populations is robust. (4) After the first few competitions, the mechanism of latency competition always detected the strongest of input activations with different latencies.
Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations

Alkali (Li+, Na+, K+, Rb+, and Cs+) and halide (F−, Cl−, Br−, and I−) ions play an important role in many biological phenomena, roles that range from stabilization of biomolecular structure, to influence on biomolecular dynamics, to key physiological influence on homeostasis and signaling. To properly model ionic interaction and stability in atomistic simulations of biomolecular structure, dynamics, folding, catalysis, and function, an accurate model or representation of the monovalent ions is critically necessary. A good model needs to simultaneously reproduce many properties of ions, including their structure, dynamics, solvation, and moreover both the interactions of these ions with each other in the crystal and in solution and the interactions of ions with other molecules. At present, the best force fields for biomolecules employ a simple additive, nonpolarizable, and pairwise potential for atomic interaction. In this work, we describe our efforts to build better models of the monovalent ions within the pairwise Coulombic and 6-12 Lennard-Jones framework, where the models are tuned to balance crystal and solution properties in Ewald simulations with specific choices of well-known water models. Although it has been clearly demonstrated that truly accurate treatments of ions will require inclusion of nonadditivity and polarizability (particularly with the anions) and ultimately even a quantum mechanical treatment, our goal was to simply push the limits of the additive treatments to see if a balanced model could be created. The applied methodology is general and can be extended to other ions and to polarizable force-field models. Our starting point centered on observations from long simulations of biomolecules in salt solution with the AMBER force fields where salt crystals formed well below their solubility limit. The likely cause of the artifact in the AMBER parameters relates to the naive mixing of the Smith and Dang chloride parameters with AMBER-adapted Åqvist cation parameters. To provide a more appropriate balance, we reoptimized the parameters of the Lennard-Jones potential for the ions and specific choices of water models. To validate and optimize the parameters, we calculated hydration free energies of the solvated ions and also lattice energies (LE) and lattice constants (LC) of alkali halide salt crystals. This is the first effort that systematically scans across the Lennard-Jones space (well depth and radius) while balancing ion properties like LE and LC across all pair combinations of the alkali ions and halide ions. The optimization across the entire monovalent series avoids systematic deviations. The ion parameters developed, optimized, and characterized were targeted for use with some of the most commonly used rigid and nonpolarizable water models, specifically TIP3P, TIP4PEW, and SPC/E. In addition to well reproducing the solution and crystal properties, the new ion parameters well reproduce binding energies of the ions to water and the radii of the first hydration shells.
A Somaclonal Variant of Rose-Scented Geranium (Pelargonium spp.) with Moderately High Content of Isomenthone in its Essential Oil

Rose-scented geranium (Pelargonium spp.), which is highly valued for its essential oil, is exclusively propagated vegetatively. Hence no genetic improvement work is possible through conventional breeding. Somaclonal variation was generated with and without in vitro mutagenesis using N-nitroso-N-methyl urea (NMU) in an Indian cultivar ‘Bourbon’, and a clone ‘Narmada’. A somaclonal variant (N75) with a moderately high content of isomenthone in its essential oil was isolated from somaclones generated after treatment of internodal explants of clone, ‘Narmada’ with 0.25 mM NMU for 1 h. The contents of isomenthone in its essential oil were 26% and 35%, respectively, in SC2/VM2 and SC3/VM3 generations (second and third vegetative generations, respectively, after in vitro mutagen treatment) as compared with 0.7% and 0.3%, respectively, in the parental clone, ‘Narmada’. The contents of alcohols and their esters (linalool, citronellol, geraniol, citronellyl formate and geranyl formate) in the essential oil of N75 in SC2/VM2 and SC3/VM3 generations were 49% and 35%, respectively, as compared with 69% and 63%, respectively, in the parental clone, ‘Narmada’. This is the first report on a chemovariant of rose-scented geranium with a moderately high content of isomenthone. All earlier reported isomenthone-rich variants of rose-scented geranium had quite high contents of isomenthone (64-71%) in their essential oils. The probable modes of origin of this somaclonal variant, its parental clone ‘Narmada’ (with very low content of isomenthone) and four earlier reported isomenthone-rich variants of Indian cultivars of geranium are discussed.
Pay for Creativity? The Complementarity between Individual Rewards And Subjective Evaluations of Non-Task-Related Performance in Incentive System Design

In this paper, I empirically investigate the impact of an organization’s reliance on collaborative creativity on the design of incentive systems. In creativity-reliant firms, i.e., firms for which the primary source of value creation lies in the creativity of their core employees, incentive system design is particularly challenging, since the nature of creative work constrains the feasibility of extrinsic incentives but at the same time creates a need for them. Accordingly, literature seems to suggest that the use of incentives renders people not creative enough, while a lack of them makes them “too creative”. I argue that a solution to this dilemma can be found in (1) acknowledging that the decision to use individual rewards is not made in isolation, and (2) viewing the incentive system as a set of complementary choices. I theoretically argue and empirically show that subjective evaluations of non-task-related performance and individual rewards are complements in creativity-reliant settings. Given the implications of this complementarity for incentive system design, I further show that reliance on collaborative creativity increases the use of individual rewards in the presence of such subjective evaluations, while it decreases its use in the their absence.
Invitation to Sociology: A Humanistic Perspective

Without belittling its scientific procedures, Professor Berger stresses the humanistic affinity of sociology with history and philosophy. It is a discipline which encourages a fuller awareness of the human world, with the purpose of bettering it. The author's comments on the social institutions which men have shaped and on the men whom these institutions, in their turn, have moulded (together with his outline of the contributions of such major sociologists as Weber, Durkheim, Veblen and Mead, among others) tell the reader just what sociology is and define the larger purpose of this social self-consciousness.
The Influence of Investment in Workplace Learning on Learning Outcomes and Organizational Performance.

Although the importance of workplace learning has been recognized in research and practice, there is little empirical support that describes how workplace learning, including both formal and informal learning, is linked to organizational performance. This study investigated the influence of investment in workplace learning on learning outcomes and organizational performance using the 2005 and 2007 Human Capital Corporate Panel survey of South Korean companies. The data were analyzed using structural equation modeling. The study found that investment in workplace learning influences organizational performance through the outcomes of workplace learning. Implications for human resource development research and practice are discussed.