Miracle-dz/UniFAR-FTUs huggingface dataset:
Design and implementation of smart HealthCare system using IoT

Diagnosis, and monitoring of health is a very important task in healthcare industry. Due to time constraint, people are not visiting hospitals, which might and possibly lead to a lot of health issues in one instant of time. Predominantly most of the healthcare systems have been developed to predict and diagnose the health of the patients by which people who are busy in their schedule can also monitor their health at regular intervals. Many studies show that early prediction is the best way to cure health because early diagnosis will help and alert the patients to know the health status. Healthcare being a global issue more particularly India being a most populated nation where majority of which live in villages deprived of healthcare facilities on real time basis continuously and regularly. With the increasing use of technology, there is an urgent need to have such a smart health monitoring system that can communicate between network devices and application which will help the patients and doctors to monitor, track and record the patient's sensitive data containing medical information. This paper depicts the idea of solving health issues using the latest technology, Internet of Things (IoT). It presents the architectural review of smart healthcare system using Internet of Things(IoT) which is aimed to provide a Better HealthCare to everyone. Using this system architecture, patient's body parameters can be measured in real time. Sensors collect patients body parameters and transfers that data to Microcontroller ATMEL 89s52 which further transfer that data to the MySQL database server. This MySQL database server manages the data and provides accessibility. The patient can view this data with the help of Android App. Which one can install in Smartphone, or Tablet. If data is abnormal then patient gets notification also care takers will get emergency message. With the help of different decision making algorithms decisions can be made easily and fast and according to it people can have access to the database. The patient can check their medical record Hence, the system provides a Better HealthCare to everyone and error free and smooth communication to patients.
Fcgamma receptor type IIIA polymorphisms influence treatment outcomes in patients with inflammatory arthritis treated with tumor necrosis factor alpha-blocking agents.

OBJECTIVE To determine whether polymorphisms in Fcgamma receptor type IIIA (FcgammaRIIIA) correlate with clinical efficacy in patients with rheumatoid arthritis (RA) and patients with psoriatic arthritis (PsA) being treated with tumor necrosis factor alpha (TNFalpha) inhibitors. METHODS The study group comprised 30 patients with RA and 5 patients with PsA. Patients were classified as being very good responders (n = 23) or nonresponders (n = 12) to therapy with TNF blocking agents. Whole blood was obtained from all patients, and DNA was extracted for FcgammaRIIIA analysis. The FcgammaRIIIA-158 polymorphism was determined using an allele-specific polymerase chain reaction assay. RESULTS The distribution of FcgammaRIIIA-158 genotypes was as follows: for F homozygous (F/F), 31.5%; for V homozygous (V/V), 11.5%; and for V/F heterozygous (V/F), 57%. Among very good responders, the distribution of alleles was as follows: for F/F, 48%; for V/V, 13%; and for V/F, 39%. Among nonresponders, the distribution of alleles was as follows: for F/F, 0%; for V/V, 8%; and for V/F, 92%. The low-affinity F/F homozygous genotype was found to be significantly associated with response to TNF inhibitor therapy (P < 0.01 by Fisher's exact test). CONCLUSION These results suggest that FcgammaRIIIA-158 polymorphisms may affect the outcome of treatment with TNF blocking agents. Better understanding of the factors affecting responses to these agents could result in improved outcomes of treatment.
Mid-Infrared Interferometry on Spectral Lines. II. Continuum (Dust) Emission Around IRC +10216 and VY Canis Majoris

The University of California Berkeley Infrared Spatial Interferometer has measured the mid-infrared visibilities of the carbon star IRC +10216 and the red supergiant VY CMa. The dust shells around these sources have been previously shown to be time variable, and these new data are used to probe the evolution of the dust shells on a decade timescale, complementing contemporaneous studies at other wavelengths. Self-consistent, spherically symmetric models at maximum and minimum light both show the inner radius of the IRC +10216 dust shell to be much larger (150 mas) than expected from the dust-condensation temperature, implying that dust production has slowed or stopped in recent years. Apparently, dust does not form every pulsational cycle (638 days), and these mid-infrared results are consistent with recent near-infrared imaging, which indicates little or no new dust production in the last 3 yr. Spherically symmetric models failed to fit recent VY CMa data, implying that emission from the inner dust shell is highly asymmetric and/or time variable.
THE 31 DEG2 RELEASE OF THE STRIPE 82 X-RAY SURVEY: THE POINT SOURCE CATALOG

We release the next installment of the Stripe 82 X-ray survey point-source catalog, which currently covers 31.3 deg2 of the Sloan Digital Sky Survey (SDSS) Stripe 82 Legacy field. In total, 6181 unique X-ray sources are significantly detected with XMM-Newton (>5σ) and Chandra (>4.5σ). This catalog release includes data from XMM-Newton cycle AO 13, which approximately doubled the Stripe 82X survey area. The flux limits of the Stripe 82X survey are 8.7 × 10−16 erg s−1 cm−2, 4.7 × 10−15 erg s−1 cm−2, and 2.1 × 10−15 erg s−1 cm−2 in the soft (0.5–2 keV), hard (2–10 keV), and full bands (0.5–10 keV), respectively, with approximate half-area survey flux limits of 5.4 × 10−15 erg s−1 cm−2, 2.9 × 10−14 erg s−1 cm−2, and 1.7 × 10−14 erg s−1 cm−2. We matched the X-ray source lists to available multi-wavelength catalogs, including updated matches to the previous release of the Stripe 82X survey; 88% of the sample is matched to a multi-wavelength counterpart. Due to the wide area of Stripe 82X and rich ancillary multi-wavelength data, including coadded SDSS photometry, mid-infrared WISE coverage, near-infrared coverage from UKIDSS and VISTA Hemisphere Survey, ultraviolet coverage from GALEX, radio coverage from FIRST, and far-infrared coverage from Herschel, as well as existing ∼30% optical spectroscopic completeness, we are beginning to uncover rare objects, such as obscured high-luminosity active galactic nuclei at high-redshift. The Stripe 82X point source catalog is a valuable data set for constraining how this population grows and evolves, as well as for studying how they interact with the galaxies in which they live.
Expression of Extracellular Matrix Components Versican, Chondroitin Sulfate, Tenascin, and Hyaluronan, and Their Association with Disease Outcome in Node-Negative Breast Cancer

Purpose: The purpose is to determine whether the levels of expression of extracellular matrix components in peritumoral stroma are predictive of disease outcome for women with node-negative breast cancer. Experimental Design: Tumor tissue from 86 patients with node-negative breast cancer was examined by immunohistochemical staining for the expression of versican, chondroitin sulfate (CS), tenascin, and hyaluronan (HA). With the exception of HA, the expression of the extracellular matrix components was measured by video image analysis. Statistical correlation of the immunohistochemical data with clinicopathological characteristics and disease outcome was performed. Results: All of the extracellular matrix components were present in the peritumoral stroma of the entire study cohort. In contrast, immunoreactivity within the cancer cell was observed in 82% of tumors for HA, 12% for CS, and 4% for tenascin; no immunostaining of cancer cells for versican was observed for any of the tumors. Cox regression and Kaplan-Meier analyses indicated that elevated expression of stromal versican predicted increased risk and rate of relapse in this cohort. Elevated expression of tenascin was predictive of increased risk and rate of death only. Although neither CS nor HA were predictive of disease outcome in this cohort, tumor size was predictive of increased risk and rate of both relapse and survival. Conclusions: Elevated expression within peritumoral stromal matrix of versican and tenascin was predictive of relapse-free and overall survival, respectively, in women with node-negative breast cancer.
Evidence for two subtypes of alpha adrenergic receptors in canine airway smooth muscle.

The contractile response of canine tracheal muscle to i.a. phenylephrine, clonidine and norepinephrine was studied isometrically in situ in 32 dogs after beta adrenergic and ganglionic blockade. Intra-arterial phenylephrine caused dose-related tracheal contraction which was not altered by yohimbine (5 microgram/kg i.a.). Prazosin (4 mg/kg i.v.) caused a 77 +/- 3% decrease in tracheal response to i.a. phenylephrine. Clonidine also caused dose-related tracheal contraction, which was not altered by prazosin (4 mg/kg i.v.) but was 95 +/- 2% blocked by 5 microgram/kg i.a. of yohimbine. Norepinephrine caused tracheal muscle contraction which was greater than both phenylephrine (P less than .05) and yohimbine (P less than .001). Prazosin (4 mg/kg i.v.) caused 53 +/- 6% blockade and yohimbine (5 microgram/kg i.a.) caused 76 +/- 2% blockade of the response to i.a. norepinephrine; prazosin plus yohimbine caused greater than 98% blockade of the response to i.a. norepinephrine. The dose-response curve to i.a. acetylcholine was not altered by treatment with prazosin (4 mg/kg i.v.) plus yohimbine (5 microgram/kg i.a.). These results demonstrate that tracheal contraction induced by sympathomimetic amines is mediated by two subtypes of alpha adrenergic receptors on tracheal muscle, alpha-1 for phenylephrine, alpha-2 for clonidine and both alpha-1 and alpha-2 for norepinephrine.
Social Skills Instruction for Adolescents with Emotional Disabilities: A Technology-Based Intervention

This study explored the use of multimedia, student-generated social skills lessons coupled with teacher facilitation to improve the social skills of middle-school students with emotional disabilities. The effects of teacher-led social skills instruction and the combination of teacher-led and multimedia student-generated social skills instruction on the perceived social behaviors of the students were compared. Maintenance of perceived student social skills over time was examined. Also evaluated were the effects of traditional and combined interventions on student knowledge of social skills. The results indicated that both interventions were effective in improving the students' social skills and their knowledge of social skills. Teachers, parents, and students all perceived that student social skills improved over the course of the study. Students appeared to have maintained the improvements from both interventions over the maintenance periods. The participating teachers perceived that the combined intervention was more effective than the traditional intervention in improving maintenance of social skills. However, parents and students did not perceive any differences in the effectiveness of the two interventions or of the two interventions over time on improving students' social skills performance.
Activity-Dependent Presynaptic Regulation of Quantal Size at the Mammalian Neuromuscular Junction In Vivo

Changes in synaptic activity alter quantal size, but the relative roles of presynaptic and postsynaptic cells in these changes are only beginning to be understood. We examined the mechanism underlying increased quantal size after block of synaptic activity at the mammalian neuromuscular junction in vivo. We found that changes in neither acetylcholinesterase activity nor acetylcholine receptor density could account for the increase. By elimination, it appears likely that the site of increased quantal size after chronic block of activity is presynaptic and involves increased release of acetylcholine. We used mice with muscle hyperexcitability caused by mutation of the ClC-1 muscle chloride channel to examine the role of postsynaptic activity in controlling quantal size. Surprisingly, quantal size was increased in ClC mice before block of synaptic activity. We examined the mechanism underlying increased quantal size in ClC mice and found that it also appeared to be located presynaptically. When presynaptic activity was completely blocked in both control and ClC mice, quantal size was large in both groups despite the higher level of postsynaptic activity in ClC mice. This suggests that postsynaptic activity does not regulate quantal size at the neuromuscular junction. We propose that presynaptic activity modulates quantal size at the neuromuscular junction by modulating the amount of acetylcholine released from vesicles.
Regulation of allantoate transport in wild-type and mutant strains of Saccharomyces cerevisiae

Accumulation of intracellular allantoin and allantoate is mediated by two distinct active transport systems in Saccharomyces cerevisiae. Allantoin transport (DAL4 gene) is inducible, while allantoate uptake is constitutive (it occurs at full levels in the absence of any allantoate-related compounds from the culture medium). Both systems appear to be sensitive to nitrogen catabolite repression, feedback inhibition, and trans-inhibition. Mutants (dal5) that lack allantoate transport have been isolated. These strains also exhibit a 60% loss of allantoin transport capability. Conversely, dal4 mutants previously described are unable to transport allantoin and exhibit a 50% loss of allantoate transport. We interpret the pleiotropic behavior of the dal4 and dal5 mutations as deriving from a functional interaction between elements of the two transport systems.
The Dual brain : hemispheric specialization in humans

Contributors to this volume have investigated and demonstrated a number of processes that function asymmetrically within the two hemispheres of the brain. This includes research concerning the extent to which cerebral hemispheres constitute distinct and complete cognitive systems with different perceptions, memories, problem-solving strategies, and personalities. The wide-ranging implications, as well as the apparent limitations, of dual brain theory are covered in detail.
High Field fMRI Reveals Thalamocortical Integration of Segregated Cognitive and Emotional Processing in Mediodorsal and Intralaminar Thalamic Nuclei

Thalamocortical loops, connecting functionally segregated, higher order cortical regions, and basal ganglia, have been proposed not only for well described motor and sensory regions, but also for limbic and prefrontal areas relevant for affective and cognitive processes. These functions are, however, more specific to humans, rendering most invasive neuroanatomical approaches impossible and interspecies translations difficult. In contrast, non-invasive imaging of functional neuroanatomy using fMRI allows for the development of elaborate task paradigms capable of testing the specific functionalities proposed for these circuits. Until recently, spatial resolution largely limited the anatomical definition of functional clusters at the level of distinct thalamic nuclei. Since their anatomical distinction seems crucial not only for the segregation of cognitive and limbic loops but also for the detection of their functional interaction during cognitive–emotional integration, we applied high resolution fMRI on 7 Tesla. Using an event-related design, we could isolate thalamic effects for preceding attention as well as experience of erotic stimuli. We could demonstrate specific thalamic effects of general emotional arousal in mediodorsal nucleus and effects specific to preceding attention and expectancy in intralaminar centromedian/parafascicular complex. These thalamic effects were paralleled by specific coactivations in the head of caudate nucleus as well as segregated portions of rostral or caudal cingulate cortex and anterior insula supporting distinct thalamo–striato–cortical loops. In addition to predescribed effects of sexual arousal in hypothalamus and ventral striatum, high resolution fMRI could extent this network to paraventricular thalamus encompassing laterodorsal and parataenial nuclei. We could lend evidence to segregated subcortical loops which integrate cognitive and emotional aspects of basic human behavior such as sexual processing.
Linguistic Processes in Sociocultural Practice

Starting from the point of view that language is essentially a social phenomenon, this book explores the interconnectedness of linguistic and social matters in a wide vareity of texts ranging from casual conversations to extracts from coursebooks. Kress demonstrates that, rather than being powerless in the face of a monolithic language system, the individual language user is constantly engaged in the processes of linguistic reconstitution and change.
Theories of perception and the concept of structure.

A condition responsive electrical switch is provided with a housing, and means is movable in the housing between opposite positions for controlling the flow of power through the switch. Means is pivotally movable in the housing for effecting actuation of the controlling means between its opposite positions, and means is operable generally in response to a certain condition for driving the actuation means to pivot it and conjointly move the controlling means toward one of its opposite positions. Means is selectively operable for biasing the actuation means against the driving means to also pivot the actuation means and effect conjoint movement of the controlling means toward the other of its opposite positions.
Fiscal storms: public spending and revenues in the aftermath of natural disasters

ABSTRACT We estimate and quantify the fiscal consequences of natural disasters using quarterly fiscal data for a large panel of countries. In our estimations, we employ a panel vector autoregression framework that also controls for the business cycle. In developed countries, we find fiscal behavior in the aftermath of disasters that can best be characterized as counter-cyclical. In contrast, we find pro-cyclical decreased spending and increasing revenues in developing countries following large natural catastrophes. These pro-cyclical fiscal dynamics are likely to worsen the adverse consequences of natural disasters on middle- and low-income countries. We quantify these dynamics. The canton of Unterwald in Switzerland is frequently ravaged by storms and inundations, and is thereby exposed to extraordinary expences. Upon such occasions the people assemble, and every one is said to declare with the greatest frankness what he is worth in order to be taxed accordingly. (The Wealth of Nations by Adam Smith, book V, chapter II, p. 359).
Freedom for speech : outdoor play and its potential for young children's conceptual, linguistic and communicative development

This research investigates the opportunities provided in different play contexts, both indoor and outdoor, for three-year-old children to play, talk and listen with peers. The analysis draws on data from an ethnographic study of boys’ and girls’ play in two family centres, two college creches and a nursery class. Observations of naturally occurring informal talk between three-year-olds were documented via note-taking, audio and video recordings and verbatim descriptions of events. One hundred and sixteen recordings of naturally occurring informal talk between three-year-olds were transcribed. Whilst analysing the linguistic strategies of questioning, repetition and appropriation within the children’s discourse it became clear that they were simultaneously learning the language system, learning in an intellectual sense and learning to communicate effectively. The study demonstrates the gendered nature of children’s peer talk as well as illustrating how peers can provide a scaffold and model for children with language delay. Various excerpts show how the transition from solitary/parallel play to collaborative play is discursively managed and expressed. The research results suggest that outdoor play facilities can be particularly beneficial for children’s conceptual, linguistic and communicative development.
Enterotoxigenic Escherichia coli TibA Glycoprotein Adheres to Human Intestine Epithelial Cells

ABSTRACT Enterotoxigenic Escherichia coli (ETEC) is capable of invading epithelial cell lines derived from the human ileum and colon. Two separate invasion loci (tia and tib) that direct noninvasive E. coli strains to adhere to and invade cultured human intestine epithelial cells have previously been isolated from the classical ETEC strain H10407 . The tib locus directs the synthesis of TibA, a 104-kDa outer membrane glycoprotein. Synthesis of TibA is directly correlated with the adherence and invasion phenotypes of the tib locus, suggesting that this protein is an adhesin and invasin. Here we report the purification of TibA and characterization of its biological activity. TibA was purified by continuous-elution preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Purified TibA was biotin labeled and then shown to bind to HCT8 human ileocecal epithelial cells in a specific and saturable manner. Unlabeled TibA competed with biotin-labeled TibA, suggesting the presence of a specific TibA receptor in HCT8 cells. These results show that TibA acts as an adhesin. Polyclonal anti-TibA antiserum inhibited invasion of ETEC strain H10407 and of recombinantE. coli bearing tib locus clones, suggesting that TibA also acts as an invasin. The ability of TibA to direct epithelial cell adhesion suggests a role for this protein in ETEC pathogenesis.
Carcinoembryonic antigen (CEA) in colonic cancer. Use in preoperative and postoperative diagnosis and prognosis.

Radioimmunoassay for serum carcinoembryonic antigen (CEA) was performed in 127 colonic cancer patients. The test results were positive in 57 (72%) of 79 patients in whom tumor was present at the time of assay. In the 51 patients tested prior to tumor resection, the incidence of positivity varied from 19% in those with localized tumors to 100% in those with metastatic disease. Preoperatively, undetectable CEA in patients with known colonic cancer suggested localized tumor and good prognosis. Strongly positive CEA test results in such patients correlated with extensive tumors and poor prognosis. Postoperatively, a positive result for serum CEA indicated presence of residual tumor. A negative CEA test result postoperatively, however, did not exclude residual tumor. Periodic CEA determination in the patients who have undergone resection of colonic cancer may detect tumor recurrence that is at a treatable stage.
The Role of Constructs in Psychological and Educational Measurement

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