Miracle-dz/UniFAR-FTUs huggingface dataset:
GEOMETRICALLY DERIVED TIMESCALES FOR STAR FORMATION IN SPIRAL GALAXIES

We estimate a characteristic timescale for star formation in the spiral arms of disk galaxies, going from atomic hydrogen (H i) to dust-enshrouded massive stars. Drawing on high-resolution H i data from The H i Nearby Galaxy Survey and 24 μm images from the Spitzer Infrared Nearby Galaxies Survey, we measure the average angular offset between the H i and 24 μm emissivity peaks as a function of radius, for a sample of 14 nearby disk galaxies. We model these offsets assuming an instantaneous kinematic pattern speed, Ωp, and a timescale, tH i↦24 μm, for the characteristic time span between the dense H i phase and the formation of massive stars that heat the surrounding dust. Fitting for Ωp and tH i↦24 μm, we find that the radial dependence of the observed angular offset (of the H i and 24 μm emission) is consistent with this simple prescription; the resulting corotation radii of the spiral patterns are typically Rcor ≃ 2.7Rs, consistent with independent estimates. The resulting values of tH i↦24 μm for the sample are in the range 1–4 Myr. We have explored the possible impact of non-circular gas motions on the estimate of tH i↦24 μm and have found it to be substantially less than a factor of 2. This implies a short timescale for the most intense phase of the ensuing star formation in spiral arms, and implies that a considerable fraction of molecular clouds exist only for a few Myr before forming stars. However, our analysis does not preclude that some molecular clouds persist considerably longer. If much of the star formation in spiral arms occurs within this short interval tH i↦24 μm, then star formation must be inefficient, in order to avoid the short-term depletion of the gas reservoir.
Emergent publics of alcohol and other drug policymaking

ABSTRACT Alcohol and other drug (AOD) policy is developed within complex networks of social, economic, and political forces. One of the key ideas informing this development is that of the ‘public’ of AOD problems and policy solutions. To date, however, little scholarly attention has been paid to notions of the public in AOD policymaking. Precisely how are publics articulated by those tasked with policy development and implementation? In this article, we explore this question in detail. We analyze 60 qualitative interviews with Australian and Canadian AOD policymakers and service providers, arguing that publics figure in these interviews as pre-existing groups that must be managed – contained or educated – to allow policy to proceed. Drawing on Michael Warner’s work, we argue that publics should be understood instead as made in policy processes rather than as preceding them, and we conclude by reframing publics as emergent collectivities of interest. In closing, we briefly scrutinize the widely accepted model of good policy development, that of ‘consultation,’ arguing that, if publics are to be understood as emergent, and therefore policy’s opportunities as more open than is often suggested, a different figure – here that of ‘conference’ is tentatively suggested – may be required.
Infrequent Loss of Luminal Differentiation in Ductal Breast Cancer Metastasis

Lymph node involvement is a major prognostic variable in breast cancer. Whether the molecular mechanisms that drive breast cancer cells to colonize lymph nodes are shared with their capacity to form distant metastases is yet to be established. In a transcriptomic survey aimed at identifying molecular factors associated with lymph node involvement of ductal breast cancer, we found that luminal differentiation, assessed by the expression of estrogen receptor (ER) and/or progesterone receptor (PR) and GATA3, was only infrequently lost in node-positive primary tumors and in matched lymph node metastases. The transcription factor GATA3 critically determines luminal lineage specification of mammary epithelium and is widely considered a tumor and metastasis suppressor in breast cancer. Strong expression of GATA3 and ER in a majority of primary node-positive ductal breast cancer was corroborated by quantitative RT-PCR and immunohistochemistry in the initial sample set, and by immunohistochemistry in an additional set from 167 patients diagnosed of node-negative and –positive primary infiltrating ductal breast cancer, including 102 samples from loco-regional lymph node metastases matched to their primary tumors, as well as 37 distant metastases. These observations suggest that loss of luminal differentiation is not a major factor driving the ability of breast cancer cells to colonize regional lymph nodes.
Biological response in various compartments of the rat lens after in vivo exposure to UVR-B analyzed by HR-MAS 1H NMR spectroscopy.

PURPOSE The purpose of the present study was to investigate metabolic changes in different compartments of the rat lens (anterior, nuclear, posterior, and equatorial) after exposure to an acute double threshold dose of ultraviolet-B radiation (UVR-B) by using high-resolution magic angle spinning (HR-MAS) (1)H nuclear magnetic resonance (NMR) spectroscopy and pattern recognition (PR) METHODS: methods. One eye in each of 28 6-week-old female albino Sprague-Dawley rats was exposed to in vivo 7.5 kJ/m2 UVR-B for 15 minutes. The contralateral eye was left unexposed. One week after irradiation, all rats were killed, and both lenses were isolated. Each lens was cored by a trephine, and the cylinder was sliced into three portions (anterior, nuclear, and posterior). The lens material that remained after the coring process was analyzed as the equatorial region. Analysis of lens metabolism was performed by HR-MAS 1H NMR spectroscopy (14.1 T; Avance DRX600; Bruker BioSpin GmbH, Rheinstetten, Germany), and the metabolic profiles were statistically analyzed by the PR method of principal component analysis (PCA). RESULTS Metabolic differences were detected among the compartments in the lens, both in samples from the contralateral nonexposed lenses and in samples from lenses exposed to in vivo UVR-B. In the rat lens, exposure to UVR-B caused changes in GSH, phosphocholine, myo-inositol, succinate, formate, and adenosine triphosphate (ATP)/adenosine diphosphate (ADP) and in levels of the amino acids phenylalanine, taurine, hypo-taurine, tyrosine, alanine, valine, isoleucine, and glutamate, that varied among lens compartments. CONCLUSIONS HR-MAS 1H NMR spectroscopy, combined with PR methods (PCA), is effective for analysis of separate parts of the intact rat lens. To understand the biochemistry of the lens, it is important to divide the lens into sections, representing functionally and anatomically distinct compartments.
User Interface Design and Evaluation

Whether you are a professional new to the user-centered design field, or an experienced designer who needs to learn the fundamentals of user interface design and evaluation, this book can lead the way. What will you get from this book? Based on a course from the Open University, UK which has been taught to over a thousand professionals and students, this book presents an overview of the field. It illustrates the benefits of a user-centered approach to the design of software, computer systems, and web sites, and provides a clear and practical discussion of requirements gathering; developing interaction design from user requirements; and user interface evaluation. The book's coverage includes established HCI topics-for example, visibility, affordance, feedback, metaphors, mental models, and the like-combined with practical guidelines for contemporary designs and current trends, which makes for a winning combination. You get a clear presentation of ideas, illustrations of concepts, using real-world applications. This book will help you develop all the skills necessary for iterative user-centered design, and provides a firm foundation for user interface design and evaluation on which to build. The readership for this book will include seasoned professionals in user interface design and usability engineering (looking for new tools with which to expand their knowledge), new people who enter the HCI field with no prior educational experience, and software developers, web application developers, and information appliance designers, who need to know more about interaction design and evaluation.
VOT production by Spanish heritage speakers in a trilingual context

ABSTRACT In several studies it is highlighted that the early acquisition of a language in the home results in phonetic and phonological benefits, and that it is not uncommon for early learners to achieve native-like pronunciation in their heritage language. However, most of these studies have been carried out with bilinguals. The present contribution aims at extending the research focus to trilingual teens, and more specifically to Spanish heritage speakers (HSs), schooled mainly in English, and taking part in a French immersion programme. How do they manage the task of learning a third phonological system? We set out to explore whether and to what extent these sequential trilinguals can produce native-like speech in all of their languages. To this end, we recorded a group of Spanish HSs while completing three picture-naming tasks (in English, Spanish, and French), which led to the production of monosyllabic and disyllabic words with a voiceless stop in stressed onset position. Our results show that they tend to produce monolingual-like stops in their dominant languages, Spanish and English, but seem to fail to do so in French. In our discussion, we resort to language dominance and context of acquisition to shed light on our findings.
An architecture for identifying emergent behavior in multi-agent systems

Multi-agent systems exhibit unexpected, emergent behavior as a result of the complexity of agent behaviors and their interactions. Despite significant research interest in the past decades, computational methods to identify and analyze emergence as it happens are still needed. This paper proposes a software architecture for identifying emergent behavior in a multi-agent system as it happens, using interval-based snapshots and emergent behavior metrics. We propose various distance functions to compare between the multi-agent system under analysis and systems that have been previously shown to exhibit emergent behavior.
Gravitational Waves from Gravitational Collapse

Gravitational wave emission from stellar collapse has been studied for more than three decades. Current state-of-the-art numerical investigations of collapse include those that use progenitors with more realistic angular momentum profiles, properly treat microphysics issues, account for general relativity, and examine non-axisymmetric effects in three dimensions. Such simulations predict that gravitational waves from various phenomena associated with gravitational collapse could be detectable with ground-based and space-based interferometric observatories. This review covers the entire range of stellar collapse sources of gravitational waves: from the accretion induced collapse of a white dwarf through the collapse down to neutron stars or black holes of massive stars to the collapse of supermassive stars.
Textual Construction of Comparative Space: How Analyst Corporate Governance Reports Redefine and Create ‘Best Practice’

Purpose The purpose of this paper is to contribute to scholarly work on the role of sell-side financial analysts in corporate governance (CG). It examines the more recent work products pertaining specifically to CG that analysts based in the USA and UK have generated in the past two decades, namely, their CGCG reports. Specifically, this paper focusses on analysing how analyst CG reports constitute a comparative space in which the governance procedures of companies are evaluated and “best practices” are created. Design/methodology/approach This study involves a social constructivist textual analysis of 48 CG reports produced by analysts based in the USA and UK between 1998 and 2009. Findings Analyst CG reports textually construct a comparative space comprising four dimensions. First, the space is constructed for some carefully edited users to evaluate the governance of companies. Second, the construction of this space requires the selection of “building materials”, i.e., governance issues included in the space that render companies amenable to evaluation and comparison. Third, by linking the range of governance issues chosen to formal regulations, firms are rendered governable and regulatory requirements reinterpreted. Lastly, by using different types of inscriptions, such as narratives and tables, the space highlights “winners”, i.e., those companies which do better than others, and constructs their governance procedures as “best practices”. Research limitations/implications This research provides a first step towards an in-depth understanding of analyst CG reports. The insights from this paper generate a range of areas for future research, including how these reports are produced and used. Originality/value This paper adds to the existing literature focussing on the role of analysts in CG. It extends previous studies by examining the more recent and debatable work products generated by analysts, namely, their CG reports, and suggests an extended CG role for them. Theoretically, analyst CG reports are conceptualised as “inscriptions” that construct “documentary reality”. The notion of “editing” is also drawn upon, to analyse a particular way in which documentary reality is constructed. Accordingly, this paper broadens the theoretical perspectives used in CG research.
Comparison of the short-term postoperative results of prone positioning and lateral decubitus positioning during thoracoscopic esophagectomy

Introduction The conventional approach during thoracoscopic esophagectomy was performed in the left lateral decubitus position (LLDP). Recently, thoracoscopic esophagectomy in the prone position (PP) has attracted the attention of surgeons. Aim To report institutional experience with thoracoscopic esophagectomy in PP and compare it with the conventional LLDP approach. Material and methods We reviewed 59 consecutive patients who had presented with esophageal cancer undergoing three-stage thoracoscopic/laparoscopic esophagectomy (TLE) from May 2011 to Dec 2013. The TLE was sequentially performed on enrolled patients in LLDP from May 2011 to Oct 2012 and in PP from Nov 2012 to Dec 2013. Immediate postoperative outcomes were collected and compared to determine differences between the 2 groups. Results Thirty-eight patients had their operations in LLDP and 21 in PP. No differences in blood loss, respiratory condition during surgery, or postoperative pain scores were observed between the 2 groups. The PP had a shorter thoracic stage duration (3.4 vs. 3.9 h; p = 0.03) and shorter intensive care unit (ICU) stay (1.0 vs. 1.5 days; p = 0.03) but yielded a similar number of lymph nodes. Incidence of complications was similar between the 2 groups, except significantly lower incidence of pneumonia in PP (0% vs. 21.1%; p = 0.04) and higher incidence of hoarseness in PP (52.4% vs. 23.7%; p = 0.03). The symptoms resolved within 3 months in all patients except in the 2 patients with vocal cord palsy. Conclusions It is feasible and safe to perform thoracoscopic esophagectomy by adopting the prone position. Thoracoscopic esophagectomy in the prone position is potentially associated with fewer major complications and shorter ICU stay.
Development of a robot balanced on a ball — Application of passive motion to transport —

This paper proposes a robot balanced on a ball. In contrast to an inverted pendulum with two wheels, such as the Segway Human Transporter, an inverted pendulum using a ball can traverse in any direction without changing its orientation, thereby enabling stable motion. Such robots can be used in place of the two-wheeled robots. The robot proposed in this paper is equipped with three omnidirectional wheels with stepping motors that drive the ball and two sets of rate gyroscopes and accelerometers as attitude sensors. The robot has a simple design; it is controlled with a 16-bit microcontroller and runs on Ni-MH batteries. It can not only stand still but also traverse on floor and pivot around its vertical axis. Inverted pendulum control is applied in two axes for attitude control, and commanded motions are converted into velocity commands for the three wheels. The mechanism, control method, and experimental results including application to transport are described in this paper.
GLOBULAR CLUSTERS WITHIN 5 OF THE GALACTIC CENTER

In the recent years we have concentrated efforts to collect Colour-Magnitude Diagrams of the globular clusters projected in the central parts of the Galaxy. So far we were able to gather photometric data in the V, I and Gunn z bandpasses, for 16 out of the 17 known clusters in the central 5 radius, most of them severely reddened. Reddening, distance and metallicity are estimated from the horizontal and red giant branches. We study the resulting cluster spatial distribution and con- clude that essentially no cluster is detected beyond the Galactic Center distance. The results favour a flattened bulge extending from the Galactic Center to 4.5 kpc from the Sun. The density distribution of the clusters follows the current models for bulge field stars. We estimate that missing clusters on the opposite side of the Galaxy bulge may amount 15 clusters similar to those detected on our side. The projected distribution of clusters is asymmetrical, with higher absorption in the southern Galactic hemisphere. The metallicity distribution of our sample clusters results similar to that of bulge field stars. The present ground-based results coupled to main sequence data of two genuine bulge clusters using the Hubble Space Tele- scope, point to a scenario of an old flat bulge with common origin for the stellar populations in both globular clusters and field. consequently not much could be inferred about their spatial distribution (Racine & Harris 1989). We now have gathered CCD Colour-Magnitude Diagrams (CMD) data for 16 out of 17 known globular clusters within 5, and these data make it possible to study the properties of this inner system. Most of these CMDs are now published with individual analyses of the clusters, and in the present work we complement them with some new results to build up the most homogeneous and updated set of information for this central sample. Globular clusters are suitable probes to trace the bulge shape. In this work we address questions related to the spatial distri- bution of the globular clusters projected close to the Galactic center such as: are clusters detected on the far side of the Galaxy; how do the detected cluster distances compare with that of the Galactic center; what is the shape of this subsystem? In Sect. 2 we determine the sample parameters. In Sect. 3 we discuss the results. Finally, in Sect. 4 the concluding remarks are given.
A new, brief questionnaire (PEQ) developed in primary health care for measuring patients' experience of interaction, emotion and consultation outcome.

BACKGROUND A deepened understanding of patients' perspectives is essential in order to improve medical communication. By changing focus from patient satisfaction to patient experiences, more immediate, personal and affective responses may be captured. OBJECTIVE Our aim was to develop a new consultation-specific questionnaire on patient experiences. METHODS The questionnaire was developed in Norwegian primary care in three main phases. Phase 1: focus groups with patients in order to identify important aspects of patients' experiences, and their words and language when describing such experiences. Phase 2: a questionnaire survey with 110 items including 660 patients. Extensive testing resulted in a reduction to 25 items on six dimensions. Phase 3: a questionnaire survey with 25 items including 1092 patients. Psychometric analyses and feedback from patients and physicians involved dimensionality and tests of validity and reliability. RESULTS A final questionnaire was produced with 18 items on five dimensions: communication; emotions; short-term outcome; barriers; and relations with the auxiliary staff. The validity and reliability estimates were highly satisfactory. Three scales were skewed while two were more equally distributed. Forty-eight per cent of the patients described less than optimal communication experiences; some communication barriers were detected in 70% of the visits and less helpful experiences with the staff were reported in 55% of the visits. Twenty-four per cent of patients left with no positive feelings, and 48% scored low on the outcome scale (knowledge, perceived result). CONCLUSIONS The patient experience questionnaire (PEQ) emphasizes what patients value the most, i.e. interaction, emotions and outcome, and may represent a valuable tool for doctors who want feedback from their patients on the function of their doctor-patient relationships.
Gene-Expression Signatures Can Distinguish Gastric Cancer Grades and Stages

Microarray gene-expression data of 54 paired gastric cancer and adjacent noncancerous gastric tissues were analyzed, with the aim to establish gene signatures for cancer grades (well-, moderately-, poorly- or un-differentiated) and stages (I, II, III and IV), which have been determined by pathologists. Our statistical analysis led to the identification of a number of gene combinations whose expression patterns serve well as signatures of different grades and different stages of gastric cancer. A 19-gene signature was found to have discerning power between high- and low-grade gastric cancers in general, with overall classification accuracy at 79.6%. An expanded 198-gene panel allows the stratification of cancers into four grades and control, giving rise to an overall classification agreement of 74.2% between each grade designated by the pathologists and our prediction. Two signatures for cancer staging, consisting of 10 genes and 9 genes, respectively, provide high classification accuracies at 90.0% and 84.0%, among early-, advanced-stage cancer and control. Functional and pathway analyses on these signature genes reveal the significant relevance of the derived signatures to cancer grades and progression. To the best of our knowledge, this represents the first study on identification of genes whose expression patterns can serve as markers for cancer grades and stages.
Measuring Trust in the Press in a Changing Media Environment

ABSTRACT The only long term trend data on trust in the American press comes from the General Social Survey (GSS). The erosion of trust in the press as measured by the GSS indicator is indisputable, but its implications for the functioning of American democracy depend on what, precisely, is being measured. In this study we use an experimental design embedded in a representative national probability sample to shed light on what people are thinking of when they say they trust or distrust the American press. Are they thinking about the sources they themselves use for news? The sources that are most popular with the population at large? An average of all possible media sources? We find that individuals express much greater trust in the press when they are asked to consider specific news sources than when they are asked to evaluate a generic news media. Our results suggest that an accessibility bias combined with the proliferation of news sources in recent years may lead individuals to think of distrusted sources when asked to answer generic media trust questions. We therefore argue that different measurement strategies are needed to successfully address trust in the press in the current news environment.