Miracle-dz/UniFAR-FTUs huggingface dataset:
Thiopentone Treatment of the Phobic Anxiety-depersonalization Syndrome a Preliminary Report [Abridged]

to such stresses, but it is considered that motivation in the ordinary sense cannot explain the chronicity of the majority of these cases, nor the stamp of a subtle cerebral disorder which is characteristic of them. Certain features suggest that a subtle, sustained disturbance in the function of the temporal lobes or limbic system may be involved in the perpetuation of the phenomenon. REFERENCES ACKNER, B. (1954) J. ment. Sci., 100, 838. BONHOEFFER, K. (1911) Allg. Z. Psychiat. , 68, 371. GAUPP, R. (1911) Z. ges. Neurol. Psychiat. , 5, 457. GRmNKER, R. R. , and SPIEGEL, J. P. (1945) War Neuroses. Philadelphia. Hoci, P., and POLATIN, P. (1949) Psychiat. Quart., 23, 248. KARDINER, A. (1941) Psychosom. Med. Monogr. SuppL., II-m. KLEIST, K. (1934) Kriegsverletzungen des Gehirns. Leipzig. KRETSCHMER, E. (1917) Z. ges. Neurol. Psychiat. , 37, 64. SARGANT, W. (1957) Battle for the Mind. London. 9 and SLATER, E. (1940) Lancet, ii, 1. SHORVON, H. J. (1946) Proc. R. Soc. Med., 39, 779. WETZEL, A. (1921) Z. ges. Neurol. Psychiat. , 65, 288. WrrrIELs, F. (1940) Psychoanal. Rev., 27, 57.
Filterbank precoders for blind equalization: polynomial ambiguity resistant precoders (PARP)

Filterbank precoding in the intersymbol interference (ISI) mitigation has recently attracted much attention. Two main areas of such research have been explored. One of them is on filterbank precoding when the ISI channel is known to both the transmitter and the receiver, while the other is on filterbank precoding when the ISI channel is not known to the transmitter or the receiver. This paper is in the second area and the aim is two-fold. We first summarize some recent results on ambiguity resistant filterbank precoders for the ISI mitigation when the ISI channel is not known at the transmitter or the receiver, i.e., for blind equalization. We then present some new results on the construction and characterization of such precoders. The theory presented in this paper applies to both single antenna (SISO) systems and multiple antenna (MIMO) systems as space-time precoding.
Quantifying and correcting for the winner's curse in genetic association studies

Genetic association studies are a powerful tool to detect genetic variants that predispose to human disease. Once an associated variant is identified, investigators are also interested in estimating the effect of the identified variant on disease risk. Estimates of the genetic effect based on new association findings tend to be upwardly biased due to a phenomenon known as the “winner's curse. ” Overestimation of genetic effect size in initial studies may cause follow‐up studies to be underpowered and so to fail. In this paper, we quantify the impact of the winner's curse on the allele frequency difference and odds ratio estimators for one‐ and two‐stage case‐control association studies. We then propose an ascertainment‐corrected maximum likelihood method to reduce the bias of these estimators. We show that overestimation of the genetic effect by the uncorrected estimator decreases as the power of the association study increases and that the ascertainment‐corrected method reduces absolute bias and mean square error unless power to detect association is high. Genet. Epidemiol. 33:453–462, 2009. © 2009 Wiley‐Liss, Inc.
Making Sense of Qualitative and Quantitative Findings in Mixed Research Synthesis Studies

The synthesis of qualitative and quantitative research findings is increasingly promoted, but many of the conceptual and methodological issues it raises have yet to be fully understood and resolved. In this article, we describe how we handled issues encountered in efforts to synthesize the findings in forty-two reports of studies of antiretroviral adherence in HIV-positive women in the course of an ongoing study to develop methods to synthesize qualitative and quantitative research findings in common domains of health-related research. Working with these reports underscored the importance of looking past method claims and ideals and directly at the findings themselves, differentiating between aggregative syntheses in which findings are assimilated and interpretive syntheses in which they are configured, and understanding the judgments involved in designating relationships between findings as confirmatory, divergent, or complementary.
The Immigration Paradox: Exploring Filipino American Psychological Distress

The immigrant paradox is the empirical trend that immigrants have better mental health than second and subsequent generations. Mossakowski (2007) found that Filipinos follow this trend, and using the same data this study builds upon the previous research by examining the relationship between cultural (ethnic identification, native language) and structural (nativity, age at immigration, and poverty in city of birth) variables. The results indicate that cultural variables are important in understanding psychological distress among Filipino Americans. Relative deprivation was not associated with psychological distress, and the effect of selective migration is explained away when language and ethnic identification are controlled. Use of native language benefits U.S. born and adult immigrant Filipinos, but is damaging to child immigrants with low ethnic identification. Suggestions for future research are discussed.
Exploring the Feasibility of a Therapeutic Music Video Intervention in Adolescents and Young Adults During Stem-Cell Transplantation

The purpose of this study was to explore the feasibility and preliminary efficacy of a therapeutic music video (TMV) intervention for adolescents and young adults (AYAs) undergoing stem-cell transplantation (SCT). Twelve AYAs (aged 11-24 years) were randomized to the TMV or an audio-book protocol. The TMV was designed to diminish symptom distress and improve coping, derived meaning, resilience, and quality of life by supporting AYAs in exploring thoughts and feelings. Six sessions with a board-certified music therapist were held twice a week for 3 weeks. The Adolescent Resilience Model guided the selection of a large, comprehensive battery of outcome measures. Major data collections occurred before admission, after intervention, and at 100 days after transplantation. Participants completed a brief set of measures at presession/postsessions 2, 4, and 6. Rates of consent, session completion, and questionnaire completion supported feasibility. Immediate follow-up measures suggest positive trends in the TMV group for hope, spirituality, confidence/mastery, and self-transcendence. Positive trends at 100 days include MOS, symptoms distress, defensive coping, spirituality, and self-transcendence. Therapeutic music video participants also demonstrated gains in quality of life. The TMV intervention may buffer the immediate after-effects of the stem-cell transplantation experience, and a larger study is warranted.
An inductorless wideband Balun-LNA for spin torque oscillator-based field sensing

This paper presents a wideband inductorless Balun-LNA targeting spin torque oscillator-based magnetic field sensing applications. The LNA consists of a CS stage combined with a cross-coupled CG stage, which offers wideband matching, noise/distortion cancellation and gain boosting, simultaneously. The Balun-LNA is implemented in a 65 nm CMOS technology, and it is fully ESD-protected and packaged. Measurement results show a bandwidth of 2 GHz-7 GHz, a voltage gain of 20 dB, an IIP3 of +2 dBm, and a maximum NF of 5 dB. The LNA consumes 3.84 mW from a 1.2 V power supply and occupies a total silicon area of 0.0044 mm2. The measurement results demonstrate that the proposed Balun-LNA is highly suitable for the STO-based field sensing applications.
Mean-field kinetic theory approach to evaporation of a binary liquid into vacuum

Evaporation of a binary liquid into near vacuum conditions has been studied using numerical solutions of a system of two coupled Enskog-Vlasov equations. Liquidvapor coexistence curves have been mapped out for different liquid compositions. The evaporation process has been investigated at a range of liquid temperatures sufficiently lower than the critical one for the vapor not to significantly deviate from the ideal behaviour. It is found that the shape of the distribution functions of evaporating atoms is well approximated by an anisotropic Maxwellian distribution with different characteristic temperatures for velocity components normal and parallel to the liquid-vapor interface. The anisotropy reduces as the evaporation temperature decreases. Evaporation coefficients are computed based on the separation temperature and the maximum concentration of the less volatile component close to the liquid-vapor interface. This choice leads to values which are almost constant in the simulation conditions.
Bayesian Inverse Reinforcement Learning

Inverse Reinforcement Learning (IRL) is the problem of learning the reward function underlying a Markov Decision Process given the dynamics of the system and the behaviour of an expert. IRL is motivated by situations where knowledge of the rewards is a goal by itself (as in preference elicitation) and by the task of apprenticeship learning (learning policies from an expert). In this paper we show how to combine prior knowledge and evidence from the expert's actions to derive a probability distribution over the space of reward functions. We present efficient algorithms that find solutions for the reward learning and apprenticeship learning tasks that generalize well over these distributions. Experimental results show strong improvement for our methods over previous heuristic-based approaches.
Local Group Invariant Representations via Orbit Embeddings

Invariance to nuisance transformations is one of the desirable properties of effective representations. We consider transformations that form a \emph{group} and propose an approach based on kernel methods to derive local group invariant representations. Locality is achieved by defining a suitable probability distribution over the group which in turn induces distributions in the input feature space. We learn a decision function over these distributions by appealing to the powerful framework of kernel methods and generate local invariant random feature maps via kernel approximations. We show uniform convergence bounds for kernel approximation and provide excess risk bounds for learning with these features. We evaluate our method on three real datasets, including Rotated MNIST and CIFAR-10, and observe that it outperforms competing kernel based approaches. The proposed method also outperforms deep CNN on Rotated-MNIST and performs comparably to the recently proposed group-equivariant CNN.
DeepProf: Performance Analysis for Deep Learning Applications via Mining GPU Execution Patterns

Deep learning applications are computation-intensive and often employ GPU as the underlying computing devices. Deep learning frameworks provide powerful programming interfaces, but the gap between source codes and practical GPU operations make it difficult to analyze the performance of deep learning applications. In this paper, through examing the features of GPU traces and deep learning applications, we use the suffix tree structure to extract the repeated patten in GPU traces. Performance analysis graphs can be generated from the preprocessed GPU traces. We further present \texttt{DeepProf}, a novel tool to automatically process GPU traces and generate performance analysis reports for deep learning applications. Empirical study verifies the effectiveness of \texttt{DeepProf} in performance analysis and diagnosis. We also find out some interesting properties of Tensorflow, which can be used to guide the deep learning system setup.
Effects of Depressive Symptoms and Family Satisfaction on Health Related Quality of Life: The Hong Kong FAMILY Study

Objective To examine the effect of depressive symptoms and satisfaction with family support (FS) on physical and mental Health Related Quality of Life (HRQoL). Methods Data were obtained from the Hong Kong FAMILY Project baseline survey in 2009–2011, which included 16,039 community residents (age ≥20). The FS was measured using the Family Adaptation, Partnership, Growth, Affection, Resolve (APGAR, range 0–10) Questionnaire. HRQoL were assessed using the SF-12 version 2. Depressive symptoms were recorded using the Patient Health Questionnaire-9 (PHQ-9). Demographic and lifestyle variables, stressful life events, perceived neighborhood cohesion were also assessed. Results In a multilevel regression model, socio-demographic and behavioral variables explained 21% and 19% of the variance in physical and mental HRQoL. The presence of depressive symptoms (PHQ-9 score ≥10, standardized coefficients, β of −1.73) and high FS (APGAR score 7–10, 1.15) were associated with mental HRQoL, after adjustment for age, education, household monthly income, drinking status, physical activity, chronic conditions, life stress and neighborhood cohesion. Not FS but the presence of depressive symptoms (β of −0.88) was associated with physical HRQoL. The presence of depressive symptoms in women than men were more associated with a poorer physical HRQoL (p<0.01) while depressive symptoms in men were associated with a decrease in mental HRQoL (p<0.001). The interaction between FS and depressive symptoms was nonsignificant in relation to HRQoL. Among those with depressive symptoms, high FS was associated with a better mental HRQoL (41.1 vs. 37.9, p<0.001) in women but not contribute to variance in men. Conclusions Higher FS and presence of depressive symptoms were significantly associated with HRQoL in general population in Hong Kong. Among those with depressive symptoms, high FS was associated with a favorable mental HRQoL in women but not men.
Statistical modelling of citation exchange between statistics journals

Rankings of scholarly journals based on citation data are often met with scepticism by the scientific community. Part of the scepticism is due to disparity between the common perception of journals’ prestige and their ranking based on citation counts. A more serious concern is the inappropriate use of journal rankings to evaluate the scientific influence of researchers. The paper focuses on analysis of the table of cross‐citations among a selection of statistics journals. Data are collected from the Web of Science database published by Thomson Reuters. Our results suggest that modelling the exchange of citations between journals is useful to highlight the most prestigious journals, but also that journal citation data are characterized by considerable heterogeneity, which needs to be properly summarized. Inferential conclusions require care to avoid potential overinterpretation of insignificant differences between journal ratings. Comparison with published ratings of institutions from the UK's research assessment exercise shows strong correlation at aggregate level between assessed research quality and journal citation ‘export scores’ within the discipline of statistics.
Incorporation of PCSK9 inhibitors into prevention of atherosclerotic cardiovascular disease

ABSTRACT Primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD) has become recently more complex than ever, leaving the clinicians perplexed with outdated guidelines and emerging evidence about new LDL-C lowering therapies. 2013 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines have focused on high intensity statin therapy for specific groups of patients, while abandoning long established LDL-C goals, a strategy which no longer seems valid. PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors have emerged as the add-on therapy on top of statins and/or ezetimibe for the treatment of hypercholesterolemia and ASCVD prevention. In several clinical trials, PCSK9 inhibitors have demonstrated their safety and robust LDL-C-lowering power. One completed cardiovascular (CV) outcomes trial (FOURIER; Further Cardiovascular Outcomes Research with PCSK9 Inhibitions in Subjects with Elevated Risk) has demonstrated that PCSK9 inhibition reduces rates of CV death as well as non-fatal stroke and MI, while another major CV outcome trial is under way (ODYSSEY-OUTCOMES). Several trials studying CV benefits of novel LDL-C-lowering therapies are also being conducted. Prompt revision of ACC/AHA guidelines is necessary. In the meantime, physicians need to use clinical judgment integrating the most recent evidence into their practice.
Scale up of BioGrout: A biological ground reinforcement method

BioGrout is a new soil improvement method based on microbiologically induced precipitation of calcium carbonate. Bacteria, which are able to convert urea into ammonium and carbonate, are injected in the soil, followed by a solution containing urea and calcium chloride. The produced carbonate precipitates with calcium. The calcium carbonate crystals form bridges between the sand grains, which increases the strength of the sand mass. The remaining ammonium chloride is extracted. In the laboratory, we proved the prospect of BioGrout as soil improvement method with sand column experiments. The next challenge was to establish homogeneous strengthening over larger soil volumes. We evaluated the new technology in a step-wise scale-up approach. First, biogrouting was applied in sand filled boxes of 1 cubic meter, simulating a single point injection. Recently, we used a large scale sand box (100 m) in which the sand was treated over a distance of 5 m using screens of injection and extraction wells. The tests showed that it was possible to turn sand biologically into sandstone (UCS up to 12 MPa) using conditions and techniques as encountered in practice. Special attention is paid to the distribution of the calcium carbonate content and geomechanical parameters within the grouted sand bodies. RÉSUMÉ BioGrout est une méthode nouvelle pour la consolidation des sols basée sur la précipitation de carbonate de calcium causée par des bactéries. Ces bactéries sont capables de convertir l'urée en ammonium et carbonate. Quand sont injectées successivement dans le sol, ces bactéries et une solution contenant du chlorure de calcium et de l'urée, le carbonate produit précipite avec le calcium. Les cristaux de carbonate de calcium soudent les grains de sable entre eux et consolide ainsi les formations sableuses. Le chlorure d'ammonium est extrait au cours du traitement. En laboratoire, la faisabilité de BioGrout en tant que méthode d'aménagement de sols a été prouvée par des expériences sur colonne de sable. Pour déterminer la faisabilité de BioGrout dans des conditions et des techniques d'injection, réalisable a l’échelle, des expériences ont été effectuées dans des conteneurs de 1 m remplies de sable, simulant un point d’injection unique et dans un conteneur plus grand de 100 m dans lequel la solution était injectée en plusieurs points et extraite à 5 M de distance des points d’injection. Les essais ont prouvé qu'il était possible de transformer biologiquement le sable en grès (UCS jusqu'à 12 MPa) dans des conditions et des techniques semblables a celles utilisées en pratique. Une attention particulière est apportée à la distribution de la teneur en carbonate de calcium et aux paramètres géo mécaniques du sable consolidé.
Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma

This randomized, controlled trial assessed the efficacy of transarterial Lipiodol (Lipiodol Ultrafluide, Laboratoire Guerbet, Aulnay‐Sous‐Bois, France) chemoembolization in patients with unresectable hepatocellular carcinoma. From March 1996 to October 1997, 80 out of 279 Asian patients with newly diagnosed unresectable hepatocellular carcinoma fulfilled the entry criteria and randomly were assigned to treatment with chemoembolization using a variable dose of an emulsion of cisplatin in Lipiodol and gelatin‐sponge particles injected through the hepatic artery (chemoembolization group, 40 patients) or symptomatic treatment (control group, 40 patients). One patient assigned to the control group secondarily was excluded because of unrecognized systemic metastasis. Chemoembolization was repeated every 2 to 3 months unless there was evidence of contraindications or progressive disease. Survival was the main end point. The chemoembolization group received a total of 192 courses of chemoembolization with a median of 4.5 (range, 1‐15) courses per patient. Chemoembolization resulted in a marked tumor response, and the actuarial survival was significantly better in the chemoembolization group (1 year, 57%; 2 years, 31%; 3 years, 26%) than in the control group (1 year, 32%; 2 years, 11%; 3 years, 3%; P = .002). When adjustments for baseline variables that were prognostic on univariate analysis were made with a multivariate Cox model, the survival benefit of chemoembolization remained significant (relative risk of death, 0.49; 95% CI, 0.29‐0.81; P = .006). Although death from liver failure was more frequent in patients who received chemoembolization, the liver functions of the survivors were not significantly different. In conclusion, in Asian patients with unresectable hepatocellular carcinoma, transarterial Lipiodol chemoembolization significantly improves survival and is an effective form of treatment.
Flow cytometric detection of bicarbonate‐induced changes in lectin binding in boar and ram sperm populations

Boar and ram spermatozoa were incubated in Tyrode's medium in the presence or absence of bicarbonate/CO2, a component believed essential for capacitation. At intervals, samples were stained with a range of FITC‐lectins to detect changes in surface glycoconjugates, using a rapid staining technique to avoid problems of lectin toxicity. The samples were then analysed directly by flow cytometry, using propidium iodide to distinguish dead cells. In the presence of bicarbonate, a live subpopulation of spermatozoa developed, which in both animal species showed higher binding affinities towards Phaseolus Vulgaris Agglutinin (PHA‐E), Sophora Japonica Agglutinin (SJA), and Soybean Agglutinin (SBA), and lower binding affinity towards Erythrina Cristagalli Lectin (ECL). In boar samples, the modified subpopulation reached a maximum after 3 hr incubation, whereas in ram samples it maximized after 1.5 hr. No changes were seen when spermatozoa were incubated in bicarbonate‐free medium. The bicarbonate‐induced changes in lectin binding were not due to the onset of acrosome reactions, because spermatozoa induced to undergo acrosome reactions with the ionophore A23187 displayed very different lectin‐binding patterns. Tested on boar spermatozoa, seminal plasma not only inhibited but reversed the bicarbonate‐induced development of the modified subpopulation. EGTA also inhibited development of boar sperm subpopulations; excess Ca2+ was unable to overcome this inhibition, suggesting that multivalent metal ions might be involved in bicarbonate's action. We conclude that bicarbonate causes a loss of surface coating material with affinity for ECL and an unmasking of binding sites for SBA, SJA and PHA‐E. A modified subpopulation of live spermatozoa is thereby established, which appears to maximize at a rate in accord with reported capacitation times. © 1995 Wiley‐Liss, Inc.