Miracle-dz/UniFAR-FTUs huggingface dataset:
Surface State Model for Conductance Responses During Thermal-Modulation of SnO$_{2}$-Based Thick Film Sensors: Part I—Model Derivation

Metal oxide gas sensors (MOXs) are widely used in olfactory electronic systems for their high sensitivity and low-cost. These sensors modify their conductivity in presence of oxidizing and reducing gases, and their performance is strictly dependent on the measurement technique adopted. In particular, it was already established by many works that a noticeable improvement in selectivity can be obtained by operating MOXs with a variable temperature. The temperature profile, however, must be tailored to the specific application, and the shape of the "optimum" profile for a given application depends both on the specific sensor and on the tested chemicals. In this context, there exists a strong interest in developing simplified models able to predict the sensor response, and aiming at a better comprehension of the mechanisms involved in sensing operations. In this paper, three simple gray-box models able to predict the behavior of some commercial thick film SnO2-based sensors in presence of oxygen and a reducing gas (CO) are proposed and discussed, whereas in a second paper the experimental validation of the model is presented
Frustrated double ionization in two-electron triatomic molecules

Using a semiclassical model, we investigate frustrated double ionization (FDI) in ${\mathrm{D}}_{3}{}^{+}$, a two-electron triatomic molecule, when driven by an intense, linearly polarized, near-infrared (800 nm) laser field. We compute the kinetic energy release of the nuclei and find a good agreement between experiment and our model. We explore the two pathways of FDI and show that, with increasing field strength, over-the-barrier ionization overtakes tunnel ionization as the underlying mechanism of FDI. Moreover, we compute the angular distribution of the ion fragments for FDI and identify a feature that can potentially be observed experimentally and is a signature of only one of the two pathways of FDI.
Conservative management of osteomyelitis in the feet of diabetic patients

Experience of conservative management of osteomyelitis in a specialized, multidisciplinary, diabetic foot clinic was reviewed. The records of all patients attending the clinic over a 10‐year period were examined retrospectively, and 22 patients with overt osteomyelitis were identified. Median age was 66 (31–87) years. In 12 cases the bone infection was a complication of a pre‐existing ulcer; the most prevalent organism cultured from swabs was Staphylococcus aureus. The main site of infection was the first toe. The total duration of antibiotic treatment was 12 weeks (median, range 5–72), and clindamycin was the most commonly used oral agent. Four patients did not respond to initial conservative therapy and proceeded to amputation, while 1 patient responded clinically but had a recurrence of osteomyelitis at the same site 6 years later. In the remaining 17 patients resolution of osteomyelitis was achieved with conservative management over a median period of follow‐up of 27 (range 5–73) months. The success of conservative therapy with prolonged courses of oral antibiotics challenges conventional advice that excision of infected bone is essential in the management of osteomyelitis affecting the foot in diabetes. © 1997 by John Wiley & Sons, Ltd.
Complex patterns of autopolyploid evolution in alfalfa and allies (Medicago sativa; Leguminosae).

PREMISE OF THE STUDY Although there is growing evidence that autopolyploidy is a widespread and important evolutionary phenomenon, it has received less attention than allopolyploidy. Medicago sativa comprises several diploid and autopolyploid taxa, including autotetraploid cultivated alfalfa, and affords an opportunity to elucidate the evolutionary history of a morphologically and genetically complex autopolyploid system. METHODS Phylogenies and haplotype networks were constructed from two chloroplast noncoding regions (rpl20-rps12 and trnS-trnG spacers) across seven diploid and polyploid infraspecific taxa of M. sativa and five additional closely related Medicago species, and genetic differentiation was estimated. KEY RESULTS The two most prominent M. sativa autopolyploids have contrasting evolutionary histories. Chloroplast data support a simple autopolyploid origin of subsp. sativa (alfalfa) from diploid subsp. caerulea, from which it is distinguishable in several quantitative characters. In contrast, morphologically identical diploid and autopolyploid cytotypes of subsp. falcata were found to possess very different chloroplast haplotypes, suggesting past introgression from M. prostrata into the polyploid. Despite the presence of hybrids between tetraploid subspecies falcata and sativa, there was little evidence of introgression of chloroplast genomes from either subspecies into the other. CONCLUSIONS Autopolyploid evolution in M. sativa is complicated and has followed very different paths in different subspecific taxa. The potential exists for gene flow in virtually all combinations of subspecies both within and between ploidies, yet despite the existence of hybrids, morphologically and genetically distinctive subspecies persist.
Convergence of discretized stochastic (interest rate) processes with stochastic drift term

For applications in finance, we study the stochastic differential equation dXs = (2βXs + δs) ds + g(Xs) dBs with β a negative real number, g a continuous function vanishing at zero which satisfies a Holder condition and δ a measurable and adapted stochastic process such that ∫t0 δu du < ∞ a.e. for all t ∈ ℝ+ and which may have a random correlation with the process X itself. In this paper, we concentrate on the Euler discretization scheme for such processes and we study the convergence in L1-supnorm and in ℋ1-norm towards the solution of the stochastic differential equation with stochastic drift term. We also check the order of strong convergence. © 1998 John Wiley & Sons, Ltd.
Cognitive Multihoming System for Energy and Cost Aware Video Transmission

To alleviate the spectrum scarcity problem in the licensed cellular networks (LCNs), we introduce a new paradigm called cognitive multihoming (CM), where a cognitive radio (CR)-enabled base station transmits to the users simultaneously over the licensed cellular bands and primary user bands in CR networks (CRNs). The CR aspect incurs lower cost, however, at the expense of higher energy consumption due to intermittent channel sensing. On the other hand, transmission via LCN is expensive because of its licensing premium. To minimize the transmission cost while meeting the users energy and received video quality constraints, sensing duration and transmission rate over CRN, transmission rate over LCN, and network selection for retransmission of lost packets are adjusted. Solution to the multiuser resource allocation optimization problem is obtained by solving the cost minimization problem of a single-user system. The problem is nonconvex which is solved using convex-concave procedure. The proposed scheme is compared with the cases where a user operates over a single network, either LCN or CRN. The system performance results indicate that the proposed CM strategy significantly decreases the cost to the users as well as serves a higher number of users while maintaining the desired video quality and energy consumption constraints.
Multimicronutrient supplementation for undernourished pregnant women and the birth size of their offspring: a double-blind, randomized, placebo-controlled trial.

OBJECTIVE To evaluate the effect of multimicronutrient supplementation for undernourished pregnant women on the birth size of their offspring, incidence of low-birth-weight infants (<2500 g), and early neonatal morbidity. DESIGN Randomized, double-blind, placebo-controlled trial. SETTING Tertiary care hospital. PARTICIPANTS Two hundred pregnant women (of 13 465 approached) with a body mass index (calculated as weight in kilograms divided by the square of height in meters) of less than 18.5 and/or a hemoglobin level of 7 to 9 g/dL were enrolled at 24 to 32 weeks of gestation. One hundred forty-six neonates (73.0%) were available for analysis of birth size and 170 (85.0%) for analysis of morbidity in the 7 days after delivery. Intervention The micronutrient supplementation group (n = 99) received a multimicronutrient supplement containing 29 vitamins and minerals once a day, from enrollment until delivery (median duration, 58 days; interquartile range, 37-77 days; compliance, 87%). The comparison group (n = 101) received placebo for 52 (15-66) days, with 85% compliance. All subjects also received supplements of iron (given in the form of ferrous sulfate, containing 60 mg of elemental iron), 60 mg/d, and folic acid, 500 mug/d. MAIN OUTCOME MEASURES Birth weight, length, midarm circumference, incidence of low birth weight, and early neonatal morbidity. RESULTS Infants in the micronutrient group were heavier by 98 g (95% confidence interval [CI], -16 to 213 g) and measured 0.80 cm (95% CI, 0.03-1.57 cm) longer and 0.20 cm (95% CI, 0.04-0.36 cm) larger in midarm circumference compared with the placebo group. Incidence of low birth weight declined from 43.1% to 16.2% with multimicronutrient supplementation a (a 70% decrease; relative risk, 0.30; 95% CI, 0.13-0.71; P=.006), and that of early neonatal morbidity declined from 28.0% to 14.8% (a 58% decrease; relative risk, 0.42; 95% CI, 0.19-0.94; P=.04). CONCLUSION Compared with iron and folic acid supplementation, the administration of multimicronutrients to undernourished pregnant women may reduce the incidence of low birth weight and early neonatal morbidity.
Predicting Unobserved Phenotypes for Complex Traits from Whole-Genome SNP Data

Genome-wide association studies (GWAS) for quantitative traits and disease in humans and other species have shown that there are many loci that contribute to the observed resemblance between relatives. GWAS to date have mostly focussed on discovery of genes or regulatory regions habouring causative polymorphisms, using single SNP analyses and setting stringent type-I error rates. Genome-wide marker data can also be used to predict genetic values and therefore predict phenotypes. Here, we propose a Bayesian method that utilises all marker data simultaneously to predict phenotypes. We apply the method to three traits: coat colour, %CD8 cells, and mean cell haemoglobin, measured in a heterogeneous stock mouse population. We find that a model that contains both additive and dominance effects, estimated from genome-wide marker data, is successful in predicting unobserved phenotypes and is significantly better than a prediction based upon the phenotypes of close relatives. Correlations between predicted and actual phenotypes were in the range of 0.4 to 0.9 when half of the number of families was used to estimate effects and the other half for prediction. Posterior probabilities of SNPs being associated with coat colour were high for regions that are known to contain loci for this trait. The prediction of phenotypes using large samples, high-density SNP data, and appropriate statistical methodology is feasible and can be applied in human medicine, forensics, or artificial selection programs.
A Comparison of Algorithms for Maximum Entropy Parameter Estimation

Conditional maximum entropy (ME) models provide a general purpose machine learning technique which has been successfully applied to fields as diverse as computer vision and econometrics, and which is used for a wide variety of classification problems in natural language processing. However, the flexibility of ME models is not without cost. While parameter estimation for ME models is conceptually straightforward, in practice ME models for typical natural language tasks are very large, and may well contain many thousands of free parameters. In this paper, we consider a number of algorithms for estimating the parameters of ME models, including iterative scaling, gradient ascent, conjugate gradient, and variable metric methods. Sur-prisingly, the standardly used iterative scaling algorithms perform quite poorly in comparison to the others, and for all of the test problems, a limited-memory variable metric algorithm outperformed the other choices.
The glossyhead1 Allele of ACC1 Reveals a Principal Role for Multidomain Acetyl-Coenzyme A Carboxylase in the Biosynthesis of Cuticular Waxes by Arabidopsis[C][W][OA]

A novel mutant of Arabidopsis (Arabidopsis thaliana), having highly glossy inflorescence stems, postgenital fusion in floral organs, and reduced fertility, was isolated from an ethyl methanesulfonate-mutagenized population and designated glossyhead1 (gsd1). The gsd1 locus was mapped to chromosome 1, and the causal gene was identified as a new allele of Acetyl-Coenzyme A Carboxylase1 (ACC1), a gene encoding the main enzyme in cytosolic malonyl-coenzyme A synthesis. This, to our knowledge, is the first mutant allele of ACC1 that does not cause lethality at the seed or early germination stage, allowing for the first time a detailed analysis of ACC1 function in mature tissues. Broad lipid profiling of mature gsd1 organs revealed a primary role for ACC1 in the biosynthesis of the very-long-chain fatty acids (C20:0 or longer) associated with cuticular waxes and triacylglycerols. Unexpectedly, transcriptome analysis revealed that gsd1 has limited impact on any lipid metabolic networks but instead has a large effect on environmental stress-responsive pathways, especially senescence and ethylene synthesis determinants, indicating a possible role for the cytosolic malonyl-coenzyme A-derived lipids in stress response signaling.
Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen

alpha 3 beta 1 (VLA-3), a member of the integrin family of cell adhesion receptors, may function as a receptor for fibronectin, laminin, and collagen. A partial cDNA clone (2.4 kb) for the human alpha 3 subunit was selected from an endothelial cell lambda gt11 cDNA library by specific antibody screening. Several overlapping cDNA clones were subsequently obtained, of a total length of 4.6 kb from various cDNA libraries. The reconstructed alpha 3 cDNA was expressed on the surface of chinese hamster ovary cells as detected by an alpha 3- specific mAb after transfection, suggesting that the cDNA is authentic. Within this sequence was an open reading frame, encoding for 1,051 amino acids, including a signal peptide of 32 residues, a long extracellular domain (959 residues), a transmembrane domain (28 residues), and a short cytoplasmic segment (32 residues). Overall, the alpha 3 amino acid sequence was 25-37% similar to the other integrin alpha subunits that are cleaved, with most similarity to the alpha 6 sequence (37%), and less similarity to those alpha subunits that have I domains (15-20%, excluding the I domain sequence itself). Features most like those in other alpha subunits are (a) the positions of 18/19 cysteine residues, (b) three potential metal binding domains of the general structure DX(D/N)X(D/N)GXXD, and (c) the predicted transmembrane domain. The mass of alpha 3 calculated from its amino acid sequence is 113,505. The human alpha 3 sequence was 89% identical to hamster galactoprotein b3, and 70% similar to the chicken CSAT antigen band 2 protein partial sequence, suggesting that these two polypeptides are homologues of human alpha 3.
ReLink: recovering links between bugs and changes

Software defect information, including links between bugs and committed changes, plays an important role in software maintenance such as measuring quality and predicting defects. Usually, the links are automatically mined from change logs and bug reports using heuristics such as searching for specific keywords and bug IDs in change logs. However, the accuracy of these heuristics depends on the quality of change logs. Bird et al. found that there are many missing links due to the absence of bug references in change logs. They also found that the missing links lead to biased defect information, and it affects defect prediction performance. We manually inspected the explicit links, which have explicit bug IDs in change logs and observed that the links exhibit certain features. Based on our observation, we developed an automatic link recovery algorithm, ReLink, which automatically learns criteria of features from explicit links to recover missing links. We applied ReLink to three open source projects. ReLink reliably identified links with 89% precision and 78% recall on average, while the traditional heuristics alone achieve 91% precision and 64% recall. We also evaluated the impact of recovered links on software maintainability measurement and defect prediction, and found the results of ReLink yields significantly better accuracy than those of traditional heuristics.
EFFECT OF ABSCISIC ACID AND JASMONIC ACID (or JA-Me) ON THE PHOTOSYNTHETIC ELECTRON TRANSPORT AND OXYGEN EVOLVING REACTIONS IN PEA PLANTS

Summary.The effect of prolonged ABA and JA-Me application to the growth medium of pea seedlings on PSII light reactions was assessed by monitoring of Hill reaction activity, fluorescence induction, kinetic behaviour of oxygen evolving PSII centres and polypeptide analysis of thylakoids and purified PSII oxygen evolving complexes (PSII OEC). Results show the significant inhibitory effect of the two endogenous plant growth regulators on PSII activity and some specific alterations in the structural organization of chloroplast membranes. Restoration of Hill reaction activity with DPC led to the conclusion that the used phytohormones have a direct effect on the PSII donor side and oxygen evolving enzyme complex itself. In addition, ABA and JA-Me treatment led to an increase in the number of PSII β centres situated in stroma lamellae regions, which are functioning by the cooperative mechanism for O 2 production. The polypeptide composition of grana and stroma lamellae vesicles confirmed this conclusion.
Deep Multi-User Reinforcement Learning for Dynamic Spectrum Access in Multichannel Wireless Networks

We consider the problem of dynamic spectrum access for network utility maximization in multichannel wireless networks. The shared bandwidth is divided into K orthogonal channels, and the users access the spectrum using a random access protocol. In the beginning of each time slot, each user selects a channel and transmits a packet with a certain attempt probability. After each time slot, each user that has transmitted a packet receives a local observation indicating whether its packet was successfully delivered or not (i.e., ACK signal). The objective is to find a multi-user strategy that maximizes a certain network utility in a distributed manner without online coordination or message exchanges between users. Obtaining an optimal solution for the spectrum access problem is computationally expensive in general due to the large state space and partial observability of the states. To tackle this problem, we develop a distributed dynamic spectrum access algorithm based on deep multi-user reinforcement leaning. Specifically, at each time slot, each user maps its current state to spectrum access actions based on a trained deep-Q network used to maximize the objective function. Experimental results have demonstrated that users are capable to learn good policies that achieve strong performance in this challenging partially observable setting only from their ACK signals, without online coordination, message exchanges between users, or carrier sensing.
Vitamin B-12 and homocysteine status in a folate-replete population: results from the Canadian Health Measures Survey.

BACKGROUND Vitamin B-12 is an important cofactor required for nucleotide and amino acid metabolism. Vitamin B-12 deficiency causes anemia and neurologic abnormalities-a cause for concern for the elderly, who are at increased risk of vitamin B-12 malabsorption. Vitamin B-12 deficiency is also associated with an increased risk of neural tube defects and hyperhomocysteinemia. The metabolism of vitamin B-12 and folate is interdependent, which makes it of public health interest to monitor biomarkers of vitamin B-12, folate, and homocysteine in a folic acid-fortified population. OBJECTIVE The objective was to determine the vitamin B-12, folate, and homocysteine status of the Canadian population in the period after folic acid fortification was initiated. DESIGN Blood was collected from a nationally representative sample of ∼5600 participants aged 6-79 y in the Canadian Health Measures Survey during 2007-2009 and was analyzed for serum vitamin B-12, red blood cell folate, and plasma total homocysteine (tHcy). RESULTS A total of 4.6% of Canadians were vitamin B-12 deficient (<148 pmol/L). Folate deficiency (<320 nmol/L) was essentially nonexistent. Obese individuals were less likely to be vitamin B-12 adequate than were individuals with a normal BMI. A total of 94.9% of Canadians had a normal tHcy status (≤13 μmol/L), and individuals with normal tHcy were more likely to be vitamin B-12 adequate and to have high folate status (>1090 nmol/L). CONCLUSIONS Approximately 5% of Canadians are vitamin B-12 deficient. One percent of adult Canadians have metabolic vitamin B-12 deficiency, as evidenced by combined vitamin B-12 deficiency and high tHcy status. In a folate-replete population, vitamin B-12 is a major determinant of tHcy.
Detection of occult nodal metastases in patients with colorectal carcinoma

Immunohistochemical study may be used for detecting micrometastases by their expression of tumor‐associated antigens. In 48 specimens of colorectal cancer from 47 patients, 49 of 249 lymph nodes (median, five per patient; range, 2‐11) examined by light microscopic study contained tumor deposits. Sections of all lymph nodes were also examined by immunohistochemical study for carcinoembryonic antigen (CEA) and epithelial membrane antigen (EMA) expression using the indirect immunoperoxidase staining method. All 49 lymph node metastases (100%) from 20 patients stained positively for CEA and 45 (92%) expressed EMA. Of the 200 lymph nodes without metastases on light microscopic examination, anti‐CEA revealed a single micrometastasis in a patient staged as Dukes' B. No additional metastases were detected with anti‐EMA. In this series of patients immunohistochemical study has, therefore, influenced the histologic staging in only one patient (2%) and thus does not offer a significant benefit over conventional histologic staging.
A retrospective study of phonetic inventory complexity in acquisition of Spanish: Implications for phonological universals

This study evaluates 39 different phonetic inventories of 16 Spanish‐speaking children (ages 0;11 to 5;1) in terms of hierarchical complexity. Phonetic featural differences are considered in order to evaluate the proposed implicational hierarchy of Dinnsen et al.'s phonetic inventory typology for English. The children's phonetic inventories are examined independently and in relation to one another. Five hierarchical complexity levels are proposed, similar to those of English and other languages, although with some language‐specific differences. These findings have implications for theoretical assumptions about the universality of phonetic inventory development, and for remediation of Spanish‐speaking children with phonological impairments.