Miracle-dz/UniFAR-FTUs huggingface dataset:
A Preliminary Evaluation of the HEADLAMP Programme for Newly Appointed Headteachers

In recent times, governmental legislation has substantially changed the nature of the role of headteachers and in doing so has underlined the centrality of their contribution to school improvement. As a consequence the training of headteachers has become a major government priority. Against this backdrop, this paper presents a preliminary evaluation of the HEADLAMP scheme for newly appointed headteachers. It is based upon a series of interviews and group discussions with a small sample of headteachers which focused upon their experience of the scheme in general, and, in particular, their opinions of the needs analysis, the training and the impact of the training in their own schools.
Alcohol consumption, sensation seeking and ski injury: a case-control study.

OBJECTIVE Alcohol consumption is known to be associated with both risk of accidental injury and with sensation seeking, and sensation seeking has been found to be common among those engaging in such high-risk activities as skiing. However, few studies have examined the joint association of alcohol consumption and sensation seeking on injury. METHOD Alcohol consumption prior to injury and sensation-seeking disposition are analyzed on 389 injured skiers (clinic sample) and 899 randomly selected uninjured skiers (trailside sample) at a Northeastern ski resort. Cases and controls were asked questions pertaining to drinking within 24 hours, amount consumed, time lapsed between the last drink and the event, skiing ability, and sensation seeking. RESULTS The clinic sample was more likely to be female, to have less skiing experience, to score lower on sensation seeking and to have been drinking within 24 hours compared to the trailside sample. However, they were less likely to have had six or more drinks within 24 hours and were more likely to report a greater time lapse between the last drink and injury or interview. A larger proportion of those who reported drinking in both samples scored high on sensation seeking compared to those who reported not drinking. Logistic regression analysis found the following variables predictive of ski injury: female, low on sensation seeking, amount of alcohol consumed prior to the event, a longer time lapsed between drinking and the event, time of day (later) and day of the week (weekend). CONCLUSIONS The data suggest that, while drinking within 24 hours is positively associated with sensation seeking, drinking and not sensation seeking is positively predictive of injury. Drinking at least 12 hours prior to skiing, not drinking in close proximity to skiing, may increase risk for accidental injury, possibly due to a hangover or residual alcohol effect in which fatigue may play a part.
Consultation in Institutions for Child Development

The study upon which this paper is based explores how child-care institutions implement new programs and practices. Specifically, in what ways do institutions that develop and implement exemplary programs differ from those that do not? And how can consultation help the less effective institutions improve their practices? Subsequent questions deal with what conditions should hold before an organization can be expected to profit from consultation and the probable influence of each consultant's theory base, orientation, and personal style on the process and outcomes of a consultation. Four child-care institutions were selected to receive consultation. To each institution was assigned a professional consultant. Although each differed from the others in theoretical approach and operational style, all agreed on a common goal: to help the institution become more effective in terms of its stated mission vis-a-vis providing services to children. Each institution had approximately 40 days of direct consultation. Subsequent to the series of consultations, an independent evaluation assessed the outcomes. The course of each of the consultations, the evaluator's findings, and the insights derived from the entire study are discussed.
Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411.

PURPOSE The primary objective of this study was to assess the 1-year survival of patients with locally advanced, unresectable pancreatic cancer treated with the combination of bevacizumab, capecitabine, and radiation. Secondary end points were toxicity, progression-free survival (PFS), and response rate (RR). PATIENTS AND METHODS Patients with locally advanced pancreatic cancer without duodenal invasion were treated with 50.4 Gy per 28 fractions to the gross tumor with concurrent capecitabine 825 mg/m(2) orally twice daily on days of radiation and bevacizumab 5 mg/kg on days 1, 15, and 29 followed by maintenance gemcitabine 1 g/m(2) weekly for 3 weeks and bevacizumab 5 mg/kg every 2 weeks, both in 4-week cycles until progression. Treatment plans were reviewed for quality assurance (QA). RESULTS Between January 2005 and February 2006, 82 eligible patients were treated. The median and 1-year survival rates were 11.9 months (95% CI, 9.9 to 14.0 months) and 47% (95% CI, 36% to 57%). Median PFS was 8.6 months (95% CI, 6.9 to 10.5), and RR was 26%. Overall, 35.4% of patients had grade 3 or greater treatment-related gastrointestinal toxicity (22.0% during chemoradiotherapy, 13.4% during maintenance chemotherapy). Unacceptable radiotherapy protocol deviations (ie, inappropriately generous volume contoured) correlated with grade 3 or greater gastrointestinal toxicity during chemoradiotherapy (45% v 18%; adjusted odds ratio, 3.7; 95% CI, 0.98 to 14.1; P = .05). CONCLUSION The addition of bevacizumab to chemoradiotherapy followed by bevacizumab and gemcitabine resulted in a similar median survival to previous Radiation Therapy Oncology Group studies in patients with locally advanced pancreatic cancer. Prospective QA may help limit toxicity in future trials.
Observational evidence of alternating zonal jets in the world ocean

Multiple zonal jets with the east‐west velocity direction alternating with latitude are discovered in satellite altimetry data. The time‐varying jets are shown to populate every part of the world ocean and its marginal seas and are best seen in the anomaly of geostrophic vorticity. At midlatitudes the jets have a meridional wavelength of about 300 kms with r.m.s. sea level, velocity and vorticity values of 2.4 cm, 6.9 cm/s and 1.5 · 10−6 s−1, correspondingly. Realistic data from the high‐resolution OGCM run on the Earth Simulator are used to justify high vertical coherence of the jets structure and relevance of the jets to an evolving mesoscale eddy field. Strong coupling between the jets and mesoscale eddies is hypothesized.
The influence of psycholinguistic variables on articulatory errors in naming in progressive motor speech degeneration

We describe an analysis of speech errors on a confrontation naming task in a man with progressive speech degeneration of 10-year duration from Pick’s disease. C.S. had a progressive non-fluent aphasia together with a motor speech impairment and early assessment indicated some naming impairments. There was also an absence of significant phonological or semantic impairment. In order to examine naming difficulties and the factors that influence his speech production errors, we selected 210 words varying in frequency, age of acquisition (AoA), imageability, phonemic length and syllable length and conducted a logistic regression analysis on a range of speech production error types (phone omissions, additions, substitutions, response delays, overall errors). No significant naming errors due to lexical access were found. The only significant predictor of speech articulation errors was phonemic length, with none of the other lexical variables influencing speech production error. The only error type predicted was phone omissions. Results suggest that C.S. ’s speech and naming errors indicate compromised speech programming/planning rather than lexical selection and we conclude that this pattern of findings is indicative of problems with motor speech production.
Feelings towards child–teacher relationships, and emotions about the teacher in kindergarten: effects on learning motivation, competence beliefs and performance in mathematics and literacy

ABSTRACT This study examined the role of kindergarten children's feelings about the perceived quality of their relationships with their teachers and their emotions towards their teachers in their competence beliefs and learning motivation (intrinsic interest, learning goals), in the impact of competence beliefs on learning motivation, and in turn in school performance in mathematics and literacy. A total of 200 kindergarten children of both genders, and a total of 30 teachers participated in this research. The children were interviewed individually in their classrooms during a regular lesson in the middle of a kindergarten year. The results showed that emotions and feelings had moderate and positive effects on competence beliefs and learning motivation (low in learning goals), and enhanced the impact of competence beliefs on learning motivation, mainly in mathematics. Competence beliefs, compared to the other variables, proved the most powerful contributor of school performance.
Leader orientation and organizational transience: An investigation using Fiedler's LPC Scale.

In spite of the increased interest in the role of situational factors as moderators of leader orientation-performance relationships, the possible role of organizational transience as a mediating variable has been ignored. The authors used Fiedler's Least Preferred Co-worker (LPC) Scale in a study of 39 construction site managers. It was found that these managers have a stronger task orientation than other occupational groups who are typically located in relatively permanent organizations. The degree of transience of construction sites (i.e. the length of projects) moderated the LPC-performance relationship.
Using the student learning framework to explore the variation in academic performance of European business students

The primary focus of this study is to explore the variation in academic performance of European Business (EB) students, using the student learning framework. Prior research has shown that students' approaches to learning and preferences for teaching influence the quality of their learning outcomes. The Approaches and Study Skills Inventory for Students (ASSIST) is used in this study to obtain quantitative information about students' approaches to learning and preferences for teaching. Academic performance is represented by students' average mark across all first-year modules. The results show that high-achieving students are more likely to adopt a strategic approach to learning and have a preference for teaching that supports understanding. They are less inclined to adopt an instrumental approach to learning.
Comparison of Transforaminal and Parasagittal Epidural Steroid Injections in Patients With Radicular Low Back Pain

Background: Epidural steroid injection (ESI), including transforaminal (TF) epidural injections and interlaminar (IL) epidural steroid injections are commonly performed procedures for the management of lumbosacral radicular pain. Parasagittal interlaminar (PIL) approach could enable higher ventral epidural spread, with fewer complications than TF. Objectives: This study aims to compare the effectiveness of PIL and TF ESI in relieving the pain and disability of patients with lumbosacral pain. Patients and Methods: This prospective study enrolled 64 patients, aged between 18 to 75 years, with a diagnosis of low back pain and unilateral lumbosacral radicular pain. The patients were randomized to receive fluoroscopically guided epidural injection, through either the PIL or TF approach. Patients were evaluated for effective pain relief [numerical rating scale (NRS) < 3] by 0 - 10 numeric rating scale (NRS) and functional improvement by the Oswestry Disability Index (ODI). Results: Effective pain relief [numeric rating scale (NRS) < 3] was observed in 77.3% (95% CI: 67‒90.5%) of patients in PIL group and 74.2% (95% CI: 62.4 - 89.4%) of patients in the TF group (P = 0.34), at 4 weeks. Mean NRS score was not significantly different between the PIL group compared to the TF group, at 4 weeks (P = 0.19). Number of patients with improved disability (measured by ODI < 20%) was not significantly different in PIL group (78% of cases) compared to the TF group (76% of cases), at 4 weeks (P = 0.21). There were no adverse effects observed in any of our patients. Conclusions: The PIL epidural injection is as effective as TF epidural injection in improving pain and functional status, in patients with chronic lumbosacral low back pain, due to disc degeneration.
Senior High School Students’ Reading Comprehension of Graded Readers

This study investigates senior high school students’ reading comprehension of graded readers outside of the classroom. Seventy-eight participants were assigned to read three graded readers written respectively from 600-word, 1200-word, and 1700-word wordlists and labeled as Level 2 (L2), Level 3 (L3), and Level 4 (L4). All participants completed post-reading comprehension tests, follow-up reading tests, and post-reading questionnaires. T-test results showed that first, females’ reading comprehension ability had grown significantly. Second, there were no significant differences between males and females’ comprehension of L2 and L3 readers, but females achieved significantly higher scores than males in L4 graded reader. Third, females significantly used more strategies than their counterparts to understand L4 graded reader. Finally, the interpretation of females’ adding and reducing the strategies to comprehend difficult text were provided. Instructional suggestions for senior high school students’ outside reading were presented.
Interference pricing in 5G ultra-dense small cell networks: a Stackelberg game approach

Being one of core characteristics for 5G cellular networks, ultra-dense small cell network is an effective approach to reuse the spectrum and achieve high data rate transmission in the wireless communication networks. However, because of sharing the spectrum resources, the interference problem among the macrocell base stations (MBS) and the small cell base stations (SCBSs) is hard to address. In this study, the authors model the scenario as a Stackelberg game, where the MBS act as the leader and all SCBSs act as followers. In the game, the MBS set its interference penalty price first, based on the prices the MBS then determines its channel allocation schemes to all SCBSs. Observing the interference penalty price and the amount of allocated channels performed by the MBS, each SCBS then determines its transmit power to achieve its optimal utility. Because of the first-move advantage, the MBS is able to predict the reactions of each SCBS and make optimal strategies. Simulation results show the correctness of the analysis and the significant benefits when the power control and channel allocation are jointly considered in the proposed schemes.
Phenolic Content and Antioxidant Activity of Hibiscus cannabinus L. Seed Extracts after Sequential Solvent Extraction

A sequential solvent extraction scheme was employed for the extraction of antioxidant compounds from kenaf (Hibiscus cannabinus L.) seeds. Yield of extracts varied widely among the solvents and was the highest for hexane extract (16.6% based on dry weight basis), while water extract exhibited the highest total phenolic content (18.78 mg GAE/g extract), total flavonoid content (2.49 mg RE/g extract), and antioxidant activities (p < 0.05). DPPH and hydroxyl radical scavenging, β-carotene bleaching, metal chelating activity, ferric thiocyanate and thiobarbituric acid reactive substances assays were employed to comprehensively assess the antioxidant potential of different solvent extracts prepared sequentially. Besides water, methanolic extract also exhibited high retardation towards the formation of hydroperoxides and thiobarbituric acid reactive substances in the total antioxidant activity tests (p < 0.05). As conclusion, water and methanol extracts of kenaf seed may potentially serve as new sources of antioxidants for food and nutraceutical applications.
Non-compliance and instrumental variation in EU democracy promotion

Abstract This article analyses the EU's response pattern to events of democratic wrongdoing in third countries. Why does the EU in some cases take a harsh position by using coercive measures and confines itself in other cases to soft instruments such as rhetorical engagement? It sheds light on this issue by employing an original dataset of non-compliance events in the ex-Soviet republics between 1993 and 2005. While existing scholarship lacks precision and is often biased towards making self-regarding motives within the foreign policy machinery the main subject of the discussion, this article widens the focus to resource, institutional and normative explanations.
StalemateBreaker: A Proactive Content-Introducing Approach to Automatic Human-Computer Conversation

Existing open-domain human-computer conversation systems are typically passive: they either synthesize or retrieve a reply provided a human-issued utterance. It is generally presumed that humans should take the role to lead the conversation and introduce new content when a stalemate occurs, and that the computer only needs to "respond. " In this paper, we propose StalemateBreaker, a conversation system that can proactively introduce new content when appropriate. We design a pipeline to determine when, what, and how to introduce new content during human-computer conversation. We further propose a novel reranking algorithm Bi-PageRank-HITS to enable rich interaction between conversation context and candidate replies. Experiments show that both the content-introducing approach and the reranking algorithm are effective. Our full StalemateBreaker model outperforms a state-of-the-practice conversation system by +14.4% p@1 when a stalemate occurs.
Supporting Text: Inferring Genome-wide Recombination Landscapes from Ad- Vanced Intercross Lines: Application to Yeast Crosses 1 Data Generation and Preprocessing 1.1 Isolation and Sequencing of Individual Segregants 1.2 Calling of Segregating Sites and Genotyping from next Generation Se- Quencing D

We sequenced 192 segregants isolated from an advanced intercross line (F12) between S. cerevisiae strains YPS128 and DBVPG6044 [1]. The F12 diploid pools, from replica 1 and 2, were sporulated in KAc for 10 days. Approximately 90% of the cells produced meiotic segregants (spores) contained in ascus. Non sporulated cells were killed by ether treatment and the ascus was digested for 1 hour using 100 µl of Zymolase (10 mg/ml) [1]. Cells were washed in sterile water and vortexed vigorously for five minutes to disperse the spores. Serial dilutions were plated in YPDA to isolate single colonies. Segregants were genotyped for the mating type (using haploid tester strains), LYS and URA (using lys and ura drop out media respectively). For each replica (1 and 2), we selected 48 Mat α, URA + segregants (genotype Mat α, We extracted DNA from the 192 segregants using the MasterPureTM DNA Purification Kit (Epicentre) using a slightly modified protocol from the one indicated by the manufacturer. Cells were inoculated in 1 ml liquid YPD at 30 • C in 1.5 ml Eppendorf tubes without shaking. The overnight cultures were washed in distilled water and resuspended in 200 µl of 50 mM EDTA and 20 µl of Zymolase (10 mg/ml) were added. Cells were incubated at 37 • C per 30 minutes to obtain spheroplast. The manufacturer protocol was followed thereafter. 50 µl of TE buffer were added to the DNA pellet and incubated 20 minutes at 65 • C to facilitate resuspension. The 192 segregants for the 4-way cross were obtained in a similar way except that meiotic spores were isolated by micromanipulation (Cubillos et al., manuscript in preparation). The extracted DNA samples were sequenced using 2 lanes of Illumina HiSeq 2000 paired end sequencing each lane containing 96 multiplexed samples. The sequencing reads and the associated statistics are available in European Nucleotide Archive (ENA) under access number ERP000780. Reads for the parental strains YPS128, DBVPG6044, Y12 and DBVPG6765 were cleaned from adapter contaminants using cutadapt 0.9 S288C reference genome (Release R64-1-1) using Stampy 1.0.18 [2] in hybrid mode with BWA 0.5. 9 [3]. Non-primary alignments and non-properly paired reads were filtered out and duplicate reads were removed using Picard 1.69 (http://picard.sourceforge.net/). Local realignment was performed on the four strains simultaneously using SRMA [4]. Base qualities were capped by their Base Alignment Qualities [5] as computed by SAMtools 0.1. 18 [6]. Single-nucleotide polymorphisms were then called …
Safety and efficacy of sperm washing in HIV-1-serodiscordant couples where the male is infected: results from the European CREAThE network

Objective:To examine the safety and effectiveness of assisted reproduction using sperm washing for HIV-1-serodiscordant couples wishing to procreate where the male partner is infected. Design and methods:A retrospective multicentre study at eight centres adhering on the European network CREAThE and involving 1036 serodiscordant couples wishing to procreate. Sperm washing was used to obtain motile spermatozoa for 3390 assisted reproduction cycles (2840 intrauterine inseminations, 107 in-vitro fertilizations, 394 intra-cytoplasmic sperm injections and 49 frozen embryo transfers). An HIV test was performed in female partners at least 6 months after assisted reproduction attempt. The outcome measures recorded were number of assisted reproduction cycles, pregnancy outcome and HIV test on women post-treatment. Results:A total of 580 pregnancies were obtained from 3315 cycles. Pregnancy outcome was unknown in 47 cases. The 533 pregnancies resulted in 410 deliveries and 463 live births. The result of female HIV testing after assisted reproduction was known in 967 out of 1036 woman (7.1% lost to follow-up). All tests recorded were negative. The calculated probability of contamination was equal to zero (95% confidence interval, 0–0.09%). Conclusion:This first multicentre retrospective study of assisted reproduction following sperm washing demonstrates the method to be effective and to significantly reduce HIV-1 transmission risk to the uninfected female partner. These results support the view that assisted reproduction with sperm washing could not be denied to serodiscordant couples in developed countries and, where possible, could perhaps be integrated into a global public health initiative against HIV in developing countries.