Miracle-dz/UniFAR-FTUs huggingface dataset:
El apoyo social percibido moderador entre el uso problemático de Internet y la sintomatología depresiva en jóvenes adultos

El uso problematico de las nuevas tecnologias puede tener consecuencias psicologicas negativas. El apoyo social y la autoestima pueden ser factores que intervengan en el desarrollo de las mismas. Por ello, este estudio tiene como objetivo analizar la relacion entre el uso problematico de Internet y el telefono movil y las variables psicologicas de depresion, ansiedad, autoestima y apoyo social percibido. Asimismo, debido a la importancia que el apoyo social tiene en este fenomeno, se ha querido saber si el apoyo social actua como moderador entre el uso problematico de las nuevas tecnologias y la sintomatologia depresiva, ansiosa y autoestima. Y, por ultimo, se ha querido comprobar si el uso problematico esta relacionado con la edad y el sexo. La muestra ha estado compuesta por 251 jovenes de entre 18 y 30 anos, con una edad media de 23, 67 anos (dt=3, 39) procedentes de la comunidad autonoma del Pais Vasco. Los participantes de este estudio han completado los cuestionarios relacionados con el uso problematico de las nuevas tecnologias (UPNT), apoyo social percibido (MOS), autoestima (Rosenberg) y sintomatologia ansiosa y depresiva (SCL-90). Los resultados han mostrado que existe relacion entre el uso problematico de Internet y el telefono movil y la sintomatologia depresiva, ansiosa, baja autoestima y bajo apoyo social percibido. Ademas, han mostrado que el apoyo social tiene un papel moderador entre el uso problematico de Internet y depresion, siendo importante profundizar en este punto en futuras investigaciones. uso problematico de las nuevas tecnologias, ansiedad, depresion, autoestima, apoyo social, jovenes.
Gene Classification and Mining of Molecular Markers Useful in Red Clover (Trifolium pratense) Breeding

Red clover (Trifolium pratense) is an important forage plant worldwide. This study was directed to broadening current knowledge of red clover's coding regions and enhancing its utilization in practice by specific reanalysis of previously published assembly. A total of 42,996 genes were characterized using Illumina paired-end sequencing after manual revision of Blast2GO annotation. Genes were classified into metabolic and biosynthetic pathways in response to biological processes, with 7,517 genes being assigned to specific pathways. Moreover, 17,727 enzymatic nodes in all pathways were described. We identified 6,749 potential microsatellite loci in red clover coding sequences, and we characterized 4,005 potential simple sequence repeat (SSR) markers as generating polymerase chain reaction products preferentially within 100–350 bp. Marker density of 1 SSR marker per 12.39 kbp was achieved. Aligning reads against predicted coding sequences resulted in the identification of 343,027 single nucleotide polymorphism (SNP) markers, providing marker density of one SNP marker per 144.6 bp. Altogether, 95 SSRs in coding sequences were analyzed for 50 red clover varieties and a collection of 22 highly polymorphic SSRs with pooled polymorphism information content >0.9 was generated, thus obtaining primer pairs for application to diversity studies in T. pratense. A set of 8,623 genome-wide distributed SNPs was developed and used for polymorphism evaluation in individual plants. The polymorphic information content ranged from 0 to 0.375. Temperature switch PCR was successfully used in single-marker SNP genotyping for targeted coding sequences and for heterozygosity or homozygosity confirmation in validated five loci. Predicted large sets of SSRs and SNPs throughout the genome are key to rapidly implementing genome-based breeding approaches, for identifying genes underlying key traits, and for genome-wide association studies. Detailed knowledge of genetic relationships among breeding material can also be useful for breeders in planning crosses or for plant variety protection. Single-marker assays are useful for diagnostic applications.
Construction and Validation of the Career and Educational Decision Self-Efficacy Inventory for Secondary Students (CEDSIS)

This study aims to construct and validate the Career and Educational Decision Self-Efficacy Inventory for Secondary Students (CEDSIS) by using a sample of 2,631 students in Hong Kong. Principal component analysis yielded a three-factor structure, which demonstrated good model fit in confirmatory factor analysis. High reliability was found for the whole scale and each subscale, and construct validity was exhibited by the positive correlations with general self-esteem. Overall, evidence indicates that CEDSIS is a valid and reliable tool for effectively and efficiently assessing the educational and career decision-making self-efficacy of secondary students. Finally, implications and limitations of this study are discussed.
Vaccine Development Specificity of the Clones and Implications for Characterization of the Fine Antigenic Antigens Cross-React with Live Tachyzoites: Excretory-Secretory Toxoplasma gondii with Infected Healthy Humans by Stimulation T Cell Clones Raised from Chronically

Excreted-secreted Ags (ESA) of Toxoplasma gondii (Tg) play an important role in the stimulation of the host immune system in both acute and chronic infections. To identify the parasite Ag(s) involved in the maintenance of T cell-mediated long term immunity, 40 ESA-speciﬁc T cell clones were derived from three chronically infected healthy subjects. All the clones were CD4 1 and recognized both ESA and live tachyzoites in a HLA-DR-restricted manner. Conversely, CD4 1 tachyzoite-speciﬁc T cell clones from the same subjects proliferated in response to ESA, pointing to shared immunodominant Ags between ESA and Tg tachyzoites. By T cell blot analysis using SDS-PAGE-fractionated parasite extracts, the following patterns of reactivity were detected. Of 25 clones, 6 recognized Tg fractions in the 24- to 28-kDa range and proliferated to puriﬁed GRA2, 5 reacted with Tg fractions in the 30- to 33-kDa range; and 4 of them proved to be speciﬁc for rSAg1. Although surface Ag (SAg1) is not a member of ESA, small amounts of this protein were present in ESA preparation by Western blot. Of 25 clones, 8 responded to Tg fractions in the 50- to 60-kDa range but not to the 55-kDa recombinant rhoptries-2 parasite Ag, and 6 did not react with any Tg fraction but proliferated in response to either ESA or total parasite extracts. In conclusion, CD4 1 T cells speciﬁc for either ESA (GRA2) or SAg1 may be involved in the maintenance of long (v/v) ﬁnal Cells The cell-associated determined The capacity of anti-MHC products mAb to inhibit the tachyzoite/Ag-induced of T cell was investigated as In T cell were with autologous irradiated (60 Gy) in the or of dilutions of or anti-HLA-ABC Cell was assessed To investigate the of cell
Diesel engine exhaust and lung cancer: an unproven association.

The risk of lung cancer associated with diesel exhaust has been calculated from 14 case-control or cohort studies. We evaluated the findings from these studies to determine whether there is sufficient evidence to implicate diesel exhaust as a human lung carcinogen. Four studies found increased risks associated with long-term exposure, although two of the four studies were based on the same cohort of railroad workers. Six studies were inconclusive due to missing information on smoking habits, internal inconsistencies, or inadequate characterization of diesel exposure. Four studies found no statistically significant associations. It can be concluded that short-term exposure to diesel engine exhaust (< 20 years) does not have a causative role in human lung cancer. There is statistical but not causal evidence that long-term exposure to diesel exhaust (> 20 years) increases the risk of lung cancer for locomotive engineers, brakemen, and diesel engine mechanics. There is inconsistent evidence on the effects of long-term exposure to diesel exhaust in the trucking industry. There is no evidence for a joint effect of diesel exhaust and cigarette smoking on lung cancer risk. Using common criteria for determining causal associations, the epidemiologic evidence is insufficient to establish diesel engine exhaust as a human lung carcinogen. Imagesp812-a
Photometric properties and scaling relations of early‐type Brightest Cluster Galaxies

We investigate the photometric properties of the early-type Brightest Cluster Galaxies (BCGs) using a carefully selected sample of 85 BCGs from the C4 cluster catalogue with a redshift of less than 0.1. We perform accurate background subtractions and surface photometry for these BCGs to 25 mag arcsec -2 in the Sloan r band. By quantitatively analysing the gradient of the Petrosian profiles of BCGs, we find that a large fraction of BCGs have extended stellar envelopes in their outskirts; more luminous BCGs tend to have more extended stellar haloes that are likely to be connected with mergers. A comparison sample of elliptical galaxies was chosen with similar apparent magnitude and redshift ranges, for which the same photometric analysis procedure is applied. We find that BCGs have steeper size-luminosity (R oc L") and Faber-Jackson (L oc σ β ) relations than the bulk of early-type galaxies. Furthermore, the power-law indices (a and β) in these relations increase as the isophotal limits become deeper. For isophotal limits from 22 to 25 mag arcsec -2 , BCGs are usually larger than the bulk of early-type galaxies, and a large fraction (∼49 per cent) of BCGs have discy isophotal shapes. The differences in the scaling relations are consistent with a scenario where the dynamical structure and formation route of BCGs may be different from the bulk of early-type galaxies; in particular dry (dissipationless) mergers may play a more important role in their formation. We highlight several possible dry merger candidates in our sample.
Nonhyperbolic reflection moveout in anisotropic media

The standard hyperbolic approximation for reflection moveouts in layered media is accurate only for relatively short spreads, even if the layers are isotropic. Velocity anisotropy may significantly enhance deviations from hyperbolic moveout. Nonhyperbolic analysis in anisotropic media is also important because conventional hyperbolic moveout processing on short spreads is insufficient to recover the true vertical velocity (hence the depth). We present analytic and numerical analysis of the combined influence of vertical transverse isotropy and layering on long‐spread reflection moveouts. Qualitative description of nonhyperbolic moveout on “intermediate” spreads (offset‐to‐depth ratio x/z < 1.7–2) is given in terms of the exact fourth‐order Taylor series expansion for P, SV, and P‐SV traveltime curves, valid for multilayered transversely isotropic media with arbitrary strength of anisotropy. We use this expansion to provide an analytic explanation for deviations from hyperbolic moveout, such as the strong.
Co-evolution of proteins with their interaction partners.

The divergent evolution of proteins in cellular signaling pathways requires ligands and their receptors to co-evolve, creating new pathways when a new receptor is activated by a new ligand. However, information about the evolution of binding specificity in ligand-receptor systems is difficult to glean from sequences alone. We have used phosphoglycerate kinase (PGK), an enzyme that forms its active site between its two domains, to develop a standard for measuring the co-evolution of interacting proteins. The N-terminal and C-terminal domains of PGK form the active site at their interface and are covalently linked. Therefore, they must have co-evolved to preserve enzyme function. By building two phylogenetic trees from multiple sequence alignments of each of the two domains of PGK, we have calculated a correlation coefficient for the two trees that quantifies the co-evolution of the two domains. The correlation coefficient for the trees of the two domains of PGK is 0. 79, which establishes an upper bound for the co-evolution of a protein domain with its binding partner. The analysis is extended to ligands and their receptors, using the chemokines as a model. We show that the correlation between the chemokine ligand and receptor trees' distances is 0.57. The chemokine family of protein ligands and their G-protein coupled receptors have co-evolved so that each subgroup of chemokine ligands has a matching subgroup of chemokine receptors. The matching subfamilies of ligands and their receptors create a framework within which the ligands of orphan chemokine receptors can be more easily determined. This approach can be applied to a variety of ligand and receptor systems.
Neuroprotective Action of Cycloheximide Involves Induction of Bcl-2 and Antioxidant Pathways

The ability of the protein synthesis inhibitor cycloheximide (CHX) to prevent neuronal death in different paradigms has been interpreted to indicate that the cell death process requires synthesis of “killer” proteins. On the other hand, data indicate that neurotrophic factors protect neurons in the same death paradigms by inducing expression of neuroprotective gene products. We now provide evidence that in embryonic rat hippocampal cell cultures, CHX protects neurons against oxidative insults by a mechanism involving induction of neuroprotective gene products including the antiapoptotic gene bcl-2 and antioxidant enzymes. Neuronal survival after exposure to glutamate, FeSO4, and amyloid β-peptide was increased in cultures pretreated with CHX at concentrations of 50–500 nM; higher and lower concentrations were ineffective. Neuroprotective concentrations of CHX caused only a moderate (20–40%) reduction in overall protein synthesis, and induced an increase in c-fos, c-jun, and bcl-2 mRNAs and protein levels as determined by reverse transcription–PCR analysis and immunocytochemistry, respectively. At neuroprotective CHX concentrations, levels of c-fos heteronuclear RNA increased in parallel with c-fos mRNA, indicating that CHX acts by inducing transcription. Neuroprotective concentrations of CHX suppressed accumulation of H2O2 induced by FeSO4, suggesting activation of antioxidant pathways. Treatment of cultures with an antisense oligodeoxynucleotide directed against bcl-2 mRNA decreased Bcl-2 protein levels and significantly reduced the neuroprotective action of CHX, suggesting that induction of Bcl-2 expression was mechanistically involved in the neuroprotective actions of CHX. In addition, activity levels of the antioxidant enzymes Cu/ Zn-superoxide dismutase, Mn-superoxide dismutase, and catalase were significantly increased in cultures exposed to neuroprotective levels of CHX. Our data suggest that low concentrations of CHX can promote neuron survival by inducing increased levels of gene products that function in antioxidant pathways, a neuroprotective mechanism similar to that used by neurotrophic factors.
Clinical usefulness of narrow band imaging magnifying colonoscopy for assessing ulcerative colitis-associated cancer/dysplasia

Background and study aims: Colitis-associated cancer/dysplasia (CC/D) can affect the life expectancy of patients with ulcerative colitis (UC). Although the utility of magnifying chromocolonoscopy has been shown, the use of optical magnification with narrow band imaging (NBI) for distinguishing CC/D from non-neoplastic lesions in patients with UC has not been reported. We evaluated whether endoscopic findings are distinguishing and thus assessed the clinical usefulness of NBI magnification for differentiating UC-associated lesions. Patients and methods: The study involved 27 patients diagnosed and treated at Hiroshima University Hospital between September 2005 and March 2015: a neoplasia group (16 lesions) and a non-neoplasia group (17 lesions). The neoplasias comprised 9 dysplastic lesions, 5 intramucosal carcinomas, and 2 submucosal carcinomas, and 17 non-neoplastic lesions. Targeted biopsy samples of suspicious lesions detected by conventional colonoscopy were classified pathologically as neoplastic or non-neoplastic, and NBI magnifying colonoscopy findings (i. e., the surface [unclear/regular/irregular/amorphous] and vascular [same as the background mucosa/regular/irregular/avascular] patterns) of the 2 lesion types were compared. Results: Irregular/amorphous surface patterns were significantly more common in neoplastic lesions than in non-neoplastic lesions (81 % [13/16] vs. 18 % [3/17], respectively, P < 0.001). Irregular/avascular vessel pattern tended to be more common in neoplastic lesions (75 % [12/16] vs. 41 % [7/17], respectively). The surface pattern correctly predicted 82 % of neoplastic lesions, and the vessel pattern correctly predicted 67 % of non-neoplastic lesions. The 2 endoscopic findings together correctly predicted 91 % of neoplastic lesions. Conclusion: Surface pattern, determined by magnifying colonoscopy with NBI, is useful for differenting between UC-associated neoplastic and non-neoplastic lesions.
The 2QZ BL Lac survey

We have optically identified a sample of 56 featureless continuum objects without significant proper motion from the 2dF quasi-stellar object (QSO) redshift survey (2QZ). The steep number-magnitude relation of the sample, n(bj) oc 10 0 . 7 b J, is similar to that derived for QSOs in the 2QZ and inconsistent with any population of Galactic objects. Follow-up high-resolution, high signal-to-noise spectroscopy of five randomly selected objects confirms the featureless nature of these sources. Assuming the objects in the sample to be largely featureless active galactic nuclei (AGN), and using the QSO evolution model derived for the 2QZ, we predict the median redshift of the sample to be z = 1.1. This model also reproduces the observed number-magnitude relation of the sample using a renormalization of the QSO luminosity function, Φ* = Φ* Q S O / 6 6 ≃ 1.65 x 10 - 8 mag - 1 Mpc - 3 . Only ∼20 per cent of the objects have a radio flux density of S 1 . 4 > 3 mJy, and further Very Large Array observations at 8.4 GHz place a 5σ limit of S 8 . 4 < 0.2 mJy on the bulk of the sample. We postulate that these objects could form a population of radio-weak AGN with weak or absent emission lines, whose optical spectra are indistinguishable from those of BL Lac objects.
Measurements of wave damping by a grease ice slick in Svalbard using off-the-shelf sensors and open-source electronics

ABSTRACT Versatile instruments assembled from off-the-shelf sensors and open-source electronics are used to record wave propagation and damping measured by Inertial Motion Units (IMUs) in a grease ice slick near the shore in Adventfjorden, Svalbard. Viscous attenuation of waves due to the grease ice slick is clearly visible by comparing the IMU data recorded by the different instruments. The frequency dependent spatial damping of the waves is computed by comparing the power spectral density obtained from the different IMUs. We model wave attenuation using the one-layer model of Weber from 1987. The best-fit value for the effective viscosity is ν = (0.95 ± 0.05 × 10−2)m2 s−1, and the coefficient of determination is R 2 = 0.89. The mean absolute error and RMSE of the damping coefficient are 0.037 and 0.044m−1, respectively. These results provide continued support for improving instrument design for recording wave propagation in ice-covered regions, which is necessary to this area of research as many authors have underlined the need for more field data.
The Impact Of Teachers’ Perceptions Of Students With High Functioning Autism On The Student’s Learning Environment

This qualitative research study examines, explores, and describes teachers' perceptions towards high functioning autistic (ASD) students and its impact on the student's learning environment in suburban elementary school inclusion classrooms. Significant themes and subthemes emerged while analyzing the data. The emergent themes categorized were 1) enriching experiences, 2) classroom challenges, 3) preparedness and knowledge, 4) accommodations, and 5) needed supports. Based on the data I concluded that teachers perceived students with ASD to positively impact the learning environment their classroom. Participants reported that ASD students are challenging to work with due to their disruptive behaviors and lower level of functioning, which impacts the student’s academic capabilities. Shifts in teaching strategies and lesson plans were reported in order to best address the student’s ASD diagnosis. Participants also reported a lack of training and feeling underprepared on how to best meet the academic and social needs of ASD students. Recommendation for school systems and educators based on the findings are for schools districts to ensure the proper training programs for teachers surround ASD; implement better systems for utilizing a team approach when working with ASD students; and implement policy change surrounding teacher schedules when teaching a class with an ASD student in it.
Genetic Algorithms as a feasible re-planning mechanism for Belief-Desire-Intention Agents

Belief-Desire-Intention (BDI) agents traditionally use a fixed, pre-defined plan library with the assumption that the environments in which they operate remain unchanged. Often agents have to operate in changing environments with the results that plans become outdated or even fail completely. The result has been much research on several approaches to re-planning mechanisms for BDI agents. Genetic Algorithms (GA) are well known as an optimization technique with wide application, however they have not been applied as a re-planning mechanism for BDI agents. This paper explores the application of GAs as a mechanism for re-planning in BDI agents in a controlled, simulated environment and shows that GAs are a feasible re-planning mechanism for BDI agents.
Cervical Cancer Screening Among Women Who Gave Birth in the US-Mexico Border Region, 2005: The Brownsville-Matamoros Sister City Project for Women’s Health

Introduction The objective of this study was to examine correlates of ever having had a Papanicolaou (Pap) test among women who recently delivered a live infant and who resided near the US-Mexico border. Methods This cross-sectional study included women who delivered a live infant in Matamoros, Mexico (n = 488) and Cameron County, Texas (n = 453). Women were interviewed in the hospital before discharge between August 21 and November 9, 2005. Multivariable logistic regression was used to estimate the odds of ever having had a Pap test. Results Significantly fewer Matamoros women (62.1%) than Cameron County women (95.7%) reported ever having had a Pap test. Only 12% of Matamoros women said they received their most recent Pap test during prenatal care, compared with nearly 75% of Cameron County women. After adjusting for potential confounders, the odds of ever having had a Pap test were 7.41 times greater in Cameron County than in Matamoros (95% confidence interval, 4.07-13.48). Conclusion The Healthy Border 2010 goals are to cut cervical cancer mortality by 20% to 30% in the border region. The significant difference in Pap test prevalence among our survey respondents may reflect that routine prenatal Pap testing is more common in the United States than in Mexico. Because women who are receiving prenatal care have increased interaction with health care providers, Matamoros providers may need to be educated about the need to screen for cervical cancer during this time.