Miracle-dz/UniFAR-FTUs huggingface dataset:
Incubators as Tools for Entrepreneurship Promotion in Developing Countries

This paper reviews the literature on incubators in developed and developing countries. We show that the concept of incubators has evolved in time according to market and firm needs. Contemporary successful incubators are profit-oriented, provide a wide range of services, focus more on intangible business services, and employ qualified managers and support staff. By drawing lessons from country experiences we assess the appropriateness of incubators as a tool for entrepreneurship promotion in developing countries. The main weaknesses of incubators in developing countries are: (i) focus on tangible services rather than intangible services, (ii) dependence on government, (iii) lack of management and qualified personnel, (iv) lack of incubator planning and creativeness in solving problems. Most successful incubators display a creative and innovative character in approaching problems of tenant companies. This is of course correlated with the quality of the incubator management staff. Moreover, incubators reflect the institutional set-up, creativity, and policy innovativeness in a society. Therefore policy on incubators should be well-integrated with other policies for entrepreneurship promotion and economic development, such as education and institutional deregulation.
Automatic Speech Emotion Recognition: A survey

The area of Automatic Speech Emotion Recognition (ASER) has garnered a lot of interest among researchers. The framework of ASER typically includes three steps viz. speech feature extraction, dimensionality reduction and feature classification. At the base of this framework lies the design and recording of the database of emotional states through which the most popular set of emotions-happiness, sadness, anger, fear, disgust, boredom (which are typically called as `archetypal emotions') and neutral among others have been obtained. This paper surveys the extent of work done in this field especially highlighting the three steps of the ASER framework. Starting with the different languages that have been explored till date for creating the databases, this paper attempts to categorize the features that have been typically extracted, enlist the dimensionality reduction techniques that have been chosen and discuss the pros and cons, if any, of the feature classifiers that have been modelled.
Characteristics of Microbial Communities in Crustal Fluids in a Deep-Sea Hydrothermal Field of the Suiyo Seamount

To directly access the sub-seafloor microbial communities, seafloor drilling has been done in a deep-sea hydrothermal field of the Suiyo Seamount, Izu-Bonin Arc, Western Pacific. In the present study, crustal fluids were collected from the boreholes, and the bacterial and archaeal communities in the fluids were investigated by culture-independent molecular analysis based on 16S rRNA gene sequences. Bottom seawater, sands, rocks, sulfide mound, and chimneys were also collected around the boreholes and analyzed for comparisons. Comprehensive analysis revealed the characteristics of the microbial community composition in the crustal fluids. Phylotypes closely related to cultured species, e.g., Alteromonas, Halomonas, Marinobacter, were relatively abundant in some crustal fluid samples, whereas the phylotypes related to Pelagibacter and the SUP05-group were relatively abundant in the seawater samples. Phylotypes related to other uncultured environmental clones in Alphaproteobacteria and Gammaproteobacteria were relatively abundant in the sand, rock, sulfide mound, and chimney samples. Furthermore, comparative analysis with previous studies of the Suiyo Seamount crustal fluids indicates the change in the microbial community composition for 3 years. Our results provide novel insights into the characteristics of the microbial communities in crustal fluids beneath a deep-sea hydrothermal field.
Cephalic neurulation in the mouse embryo analyzed by SEM and morphometry

A detailed account of mouse neurulation is given based mostly on SEM analysis over 20 hr of development. Many observations and measurements were made on staged living embryos and on embryos prepared for scanning and light microscopy to help deduce what mechanisms may contribute to neural tube formation. Each‐lateral half of the early cephalic neural plate makes a convex bulge, opposite to the way it must fold to form a tube. Underlying mesenchyme and matrix are reported to have a role in forming these bulges. Processes that form the tube must overcome this opposed folding and the forces that produce it. Cranial flexure begins long before tube formation. The flexure commences at the rostral tip of the cephalic neural plate, then the apex of the flexure migrates caudally to the mesencephalic region. Early appearance of this flexure imposes a mechanical impediment to tube closure in forebrain and midbrain regions. Tube closure begins in the cervical region exactly where the neural plate is reflected dorsally by a bend in the embryo. This bend may mechanically assist closure in this region. Cells of the mouse neural plate are reported to contain organized microfilaments and microtubules, and the plate cells appear to change shape (reduce apical area and increase cell height) in the same manner as that suggested in embryos of some other species to contribute to neural tube formation. Measurements show that the lateral edges of the cephalic neural plate elongate craniocaudally more than the midline of the plate through each period. This elongation could contribute to the folding of the plate into a tube. The progress of cranial ventral flexure pauses while tube formation occurs, but edge elongation continues, presumably contributing to tube formation. There is considerable increase in volume of the neural plate during tube closure, and cell proliferation and enlargement of daughter cells seem sufficient to account for this growth. Mitotic spindles are positioned to place the majority of the daughter cells into the long axis of the neural plate, so ordered growth may be the main mechanism of elongation of the plate in the craniocaudal direction, which in turn may assist in tube formation. Mouse cephalic neural plates appear overlying already segmented cranial mesenchyme according to previous reports, and neuromeres develop precociously in the open plates, where their positions correlate exactly with the underlying segmented mesenchyme.
A bit-map-assisted energy-efficient MAC scheme for wireless sensor networks

Low-energy characteristics of wireless sensor networks (WSNs) pose a great design challenge for MAC control design. Recent studies have proposed different intra-cluster communication bit-map-assisted (BMA) MAC protocol for large-scale cluster-based WSNs. BMA is intended for event-driven applications, where sensor nodes transmit data to the cluster head only if significant events are observed. In addition, we provide the energy and packet latency analytical models for BMA, conventional TDMA, and energy efficient TDMA (E-TDMA) when used as intra-cluster MAC schemes. Our results show that BMA is superior for the cases of low and medium traffic loads, relatively few sensor nodes per cluster, and relatively large data packet sizes. In addition, BMA performs better than the TDMA-based MAC schemes in terms of average packet latency.
Developmental Change in Action Perception: Is Motor Experience the Cause?

Human actions are complex stimuli containing several perceptual dimensions an observer could attend to. Research indicates that attention to the perceptual dimensions of action undergoes a process of perceptual narrowing between 4 and 10 months, during which infants’ attention to configural and temporal information in action decreases over time, while attention to hand information is maintained. This research explored whether infants’ active experience with grasping is related to perceptual narrowing in action. Across two studies, we tested 6-month-old infants’ attention to changes in these action dimensions and also assessed their grasping ability. Infants who were more proficient at grasping showed a pattern more consistent with perceptual narrowing (decreasing attention to configural and temporal information) relative to those less proficient at grasping, especially for attention to configural information. In addition, attention to hand information appears to undergo U-shaped development between 4 and 10 months, as 6-month-olds did not recover attention to the hand change. These findings add to a growing body of research showing that infants’ motor experience broadly influences their perception of others’ action and may follow a complex developmental pathway that diverges from perceptual narrowing over the first year.
Relationship between Personality and Organizational Citizenship Behavior: Does Personality Influence Employee Citizenship?

This study examines the relationship between personality and Organizational Citizenship Behavior (OCB). Hierarchical regression analysis on data from 164 employees working in the service sector in Dubai-after controlling for work locus of control and organizational justice- indicated that openness to experience, conscientiousness, and emotional stability were valid predictors for OCB. However, both extraversion and agreeableness showed no significant relationship with OCB. The intriguing finding of this study is that openness was significantly related to OCB. This differs from prior research on openness that found few significant relationships. The current study shows that openness to experience is a crucial personality characteristic that is related to a person’s capability to perform OCB.
Characterization of a Small Auxin-Up RNA (SAUR)-Like Gene Involved in Arabidopsis thaliana Development

The root of Arabidopsis thaliana is used as a model system to unravel the molecular nature of cell elongation and its arrest. From a micro-array performed on roots that were treated with aminocyclopropane-1-carboxylic acid (ACC), the precursor of ethylene, a Small auxin-up RNA (SAUR)-like gene was found to be up regulated. As it appeared as the 76th gene in the family, it was named SAUR76. Root and leaf growth of overexpression lines ectopically expressing SAUR76 indicated the possible involvement of the gene in the division process. Using promoter::GUS and GFP lines strong expression was seen in endodermal and pericycle cells at the end of the elongation zone and during several stages of lateral root primordia development. ACC and IAA/NAA were able to induce a strong up regulation of the gene and changed the expression towards cortical and even epidermal cells at the beginning of the elongation zone. Confirmation of this up regulation of expression was delivered using qPCR, which also indicated that the expression quickly returned to normal levels when the inducing IAA-stimulus was removed, a behaviour also seen in other SAUR genes. Furthermore, confocal analysis of protein-GFP fusions localized the protein in the nucleus, cytoplasm and plasma membrane. SAUR76 expression was quantified in several mutants in ethylene and auxin-related pathways, which led to the conclusion that the expression of SAUR76 is mainly regulated by the increase in auxin that results from the addition of ACC, rather than by ACC itself.
A hybrid BLE and Wi-Fi localization system for the creation of study groups in smart libraries

Campus libraries in modern universities provide students with group study areas where they can work and study collaboratively. In this paper, we propose a complete solution for the creation of study groups in future smart libraries featuring (i) a smartphone application to create study groups, (ii) a hybrid Bluetooth Low Energy (BLE) and Wi-Fi indoor positioning system to localize study groups and (iii) a server-based infrastructure based on MQTT and Node-RED to advertise study groups to other students. We describe in details all components of the architecture and perform an experimental evaluation of the indoor positioning system in a realistic scenario.
Azide interference with bilirubin determinations in which Ehrlich's reagent is used.

A recent Letter by Eckfeldt et al. (1) recalled some of our unpublished findings of a few years ago, showing the effect of sodium azide on continuous-flow (SMA 12/60) measurements (Table 1). The azide interference with total bilirubin determinations they reported can be also be seen in our results, although not conspicuously. As can be seen in Table 1, measurements other than bili-. rubin may be affected, and quite possibly, creatine kinase and alkaline phosphatase are depressed and apparent calcium is elevated with increased aside concentrations. Tests that were unaffected include lactate dehydrogenase, aspartate aminotransferase, creatinine, uric acid, phosphorus, albumin, protein, and cholesterol. The analysis of lyophilized sera (Versatol) reconstituted with identical concentrations of sodium azide gave similar, confirming results.
Algorithm of athletes’ fitness structure individual features’ determination with the help of multidimensional analysis (on example of basketball)

Мета : представити основні закономірності визначення індивідуальних особливостей структури підготовленості атлетів за допомогою методів багатовимірного аналізу (на прикладі баскетболу). Матеріал : У дослідженні взяли участь кваліфіковані баскетболісти (n = 54). Педагогічне тестування проводилося за 12 тестами, що застосовуються в збірних командах України та Росії. При виконанні кожного тесту надавалися 3 спроби, фіксувався кращий результат. Тести проводилися протягом 2-3 тренувальних занять. Результати : розроблена загальна схема шляхів індивідуалізації процесу підготовки атлетів. Для кожного атлета визначалися групи провідних і відстаючих факторів в індивідуальній структурі підготовленості. Процес підготовки атлетів повинен містити базовий і варіативний компонент. Базовий компонент становить 70% засобів в загальній системі підготовки атлетів. Варіативний компонент становить 30% засобів: є застосування індивідуальних програм підготовки. Процентне співвідношення засобів в індивідуальних програмах підготовки варіює залежно від: провідного фактору в індивідуальній структурі підготовленості; періоду індивідуальної динаміки змагальної результативності. У кожному мікроциклі 30% часу відводиться на індивідуальну підготовку гравців: атлети отримують індивідуальні завдання; в міру необхідності формуються групи на основі даних кластерного аналізу. Висновки. При розробці індивідуальних програм підготовки акцент слід робити на розвиток провідних факторів в індивідуальній факторній структурі підготовленості атлетів. Застосування індивідуальних програм підготовки в поєднанні з універсальними методами індивідуалізації створює передумови для підвищення ефективності змагальної діяльності.
Teacher Evaluation Policy Tools: Principals’ Selective Use in Instructional Leadership

ABSTRACT This longitudinal, qualitative study examined perspectives of principals as they implemented a dramatically changed teacher evaluation system. The concept of policy tools was used to analyze principals’ responses. Multiple policy components were legislated and intended to be equally adopted by schools. However, principals did not equally support or use all the tools to the same degree. They supported and extensively used the rubric for instructional leadership and supervision with teachers, and integrated instructional growth components into their leadership practices. Principals modified or minimally supported accountability policy tools likely to promote conflict or competition instead of collaboration and professional growth.
Differential Responses to Wnt and PCP Disruption Predict Expression and Developmental Function of Conserved and Novel Genes in a Cnidarian

We have used Digital Gene Expression analysis to identify, without bilaterian bias, regulators of cnidarian embryonic patterning. Transcriptome comparison between un-manipulated Clytia early gastrula embryos and ones in which the key polarity regulator Wnt3 was inhibited using morpholino antisense oligonucleotides (Wnt3-MO) identified a set of significantly over and under-expressed transcripts. These code for candidate Wnt signaling modulators, orthologs of other transcription factors, secreted and transmembrane proteins known as developmental regulators in bilaterian models or previously uncharacterized, and also many cnidarian-restricted proteins. Comparisons between embryos injected with morpholinos targeting Wnt3 and its receptor Fz1 defined four transcript classes showing remarkable correlation with spatiotemporal expression profiles. Class 1 and 3 transcripts tended to show sustained expression at “oral” and “aboral” poles respectively of the developing planula larva, class 2 transcripts in cells ingressing into the endodermal region during gastrulation, while class 4 gene expression was repressed at the early gastrula stage. The preferential effect of Fz1-MO on expression of class 2 and 4 transcripts can be attributed to Planar Cell Polarity (PCP) disruption, since it was closely matched by morpholino knockdown of the specific PCP protein Strabismus. We conclude that endoderm and post gastrula-specific gene expression is particularly sensitive to PCP disruption while Wnt-/β-catenin signaling dominates gene regulation along the oral-aboral axis. Phenotype analysis using morpholinos targeting a subset of transcripts indicated developmental roles consistent with expression profiles for both conserved and cnidarian-restricted genes. Overall our unbiased screen allowed systematic identification of regionally expressed genes and provided functional support for a shared eumetazoan developmental regulatory gene set with both predicted and previously unexplored members, but also demonstrated that fundamental developmental processes including axial patterning and endoderm formation in cnidarians can involve newly evolved (or highly diverged) genes.
Cooperative networked stabilisability of linear systems with measurement noise

This paper investigates the problem of stabilising a linear, time-invariant plant with multiple controllers and noisy sensors over a digital network. A necessary and (almost) sufficient condition for determining networked uniform stabilisability, is derived, in terms of the feasibility of a set of linear inequalities involving the unstable eigenvalues of the plant and the various channel data rates. This provides a nearly exact characterisation, up to boundary points, of the region of all channel data rate combinations that permit uniform stability to be achieved. The auxiliary variables in this characterisation have a natural interpretation as the effective rates of information flow through the network, associated with each unstable mode. When channel rates are set to either zero or infinity, this agrees with a classical result on decentralised stabilisability under linear time-varying control.
The MATCHIT Automaton: Exploiting Compartmentalization for the Synthesis of Branched Polymers

We propose an automaton, a theoretical framework that demonstrates how to improve the yield of the synthesis of branched chemical polymer reactions. This is achieved by separating substeps of the path of synthesis into compartments. We use chemical containers (chemtainers) to carry the substances through a sequence of fixed successive compartments. We describe the automaton in mathematical terms and show how it can be configured automatically in order to synthesize a given branched polymer target. The algorithm we present finds an optimal path of synthesis in linear time. We discuss how the automaton models compartmentalized structures found in cells, such as the endoplasmic reticulum and the Golgi apparatus, and we show how this compartmentalization can be exploited for the synthesis of branched polymers such as oligosaccharides. Lastly, we show examples of artificial branched polymers and discuss how the automaton can be configured to synthesize them with maximal yield.
Beyond Endoscopy and special forms on GL(2)

Abstract We carry out (with technical modifications) some cases of a procedure proposed by R. Langlands in Beyond Endoscopy. This gives a new proof of the classification of “dihedral forms” on GL(2), avoiding endoscopic methods: instead, it uses an infinite limiting process in the trace formula. We also explain the relationship of Langlands' idea to the results of [10] that count automorphic forms associated to Galois representations. We prove results of a similar nature over an arbitrary number field. The main tool is a version of the relative trace formula, namely a slight variant (for PGL(2)) of the Kuznetsov-Bruggeman-Miatello formula.
Outcome of childhood acute promyelocytic leukemia treated using a modified AIDA protocol

Background Combination treatment with all-trans-retinoic acid (ATRA) and anthracycline-based chemotherapy has led to major advances in the treatment of acute promyelocytic leukemia (APL). Methods In this study, we reviewed the outcome of pediatric APL patients treated using a modified AIDA protocol at our institution. Results Between May 1999 and December 2007, 23 patients were diagnosed with APL at the Department of Pediatrics, Saint Mary's Hospital, The Catholic University of Korea. Eleven patients were male (48%) (median age at diagnosis, 11 (range, 2-14) years). The treatment protocol consisted of remission induction (achieved by coadministration of ATRA and idarubicin), 3 courses of consolidation treatment, and 2 years of maintenance treatment during which ATRA was also administered. Three patients died early during remission induction due to CNS hemorrhage. The remaining 20 patients achieved complete remission (CR), with an overall CR rate of 87%. Two patients relapsed and died, and another patient died of pneumonia unrelated to APL. Four patients (17%) were diagnosed with ATRA syndrome, and all patients showed resolution of symptoms. The event-free survival (EFS) and overall survival (OS) of the cohort were 78.3±8.6% and 76.3±9.5%, respectively. Initial WBC count at diagnosis was the only significant prognostic factor for the rate of CR (P=0.039) and OS (P=0.039). Conclusion A modified AIDA protocol for the treatment of childhood APL leads to improved EFS and OS, with limited ATRA syndrome-associated toxicity. Active monitoring and treatment of patients with high initial WBC counts may help in reducing mortality.
Transition

Zusammenfassung Entzündlich-rheumatische Erkrankungen des Kindes- und Jugendalters, wie z. B. die juvenile idiopathische Arthritis, gehen mit erhöhten Risiken für Morbidität, funktionelle Behinderung und Einschränkungen im sozialen Bereich einher. Bei jedem zweiten Jugendlichen ist die Erkrankung beim Eintritt ins Erwachsenenalter noch aktiv. Somit besteht bei vielen Patienten ein fachspezifischer Betreuungsbedarf über das Jugendalter hinaus und dementsprechend die Notwendigkeit einer Weiterbetreuung in der Erwachsenenmedizin. Der Übergang in die Erwachsenenmedizin ist für Jugendliche ein eher schwieriger Prozess und bedarf beim Vorliegen einer chronischen Erkrankung einer genauen Vorbereitung und Begleitung, damit eine kontinuierliche qualifizierte Betreuung gesichert und gesundheitliche Schäden verhindert werden. Hierfür wurden in den letzten Jahren an mehreren kinder- und jugendrheumatologischen Einrichtungen spezielle Betreuungsangebote geschaffen und dadurch die Versorgungssituation junger Rheumatiker verbessert. Nach einem Gutachten des Sachverständigenrates ist sie dennoch weiterhin als defizitär einzuschätzen. Viele junge Rheumatiker sind mit ungenügendem Krankheitswissen ausgestattet und unzureichend auf den Betreuungswechsel vorbereitet. Von denjenigen, die die internistische Rheumatologie erreichen, kommt ein Teil nicht mit der neuen Betreuungssituation zurecht und ist entsprechend unzufrieden. Eine weitere Verbesserung der Versorgungsstrukturen ist deshalb notwendig, um einen harmonischen, medizinisch erfolgreichen und auch kontinuierlichen Wechsel in die Erwachsenenmedizin sicherzustellen.