Miracle-dz/UniFAR-FTUs huggingface dataset:
Life after unsuccessful IVF treatment in an assisted reproduction unit: a qualitative analysis of gains through loss among Chinese persons in Hong Kong.

BACKGROUND Previous studies examining experiences of infertility focused mainly on the aspect of loss but neglected the possible gains realized through surviving the experience of infertility. The success rate of IVF remains relatively low, and we used the strengths perspective to examine adjustment after unsuccessful treatment. This study aims to provide an in-depth description of the gains perceived by Chinese men and women and how they re-constructed their lives after unsuccessful IVF treatment. METHODS Four couples and another six women who experienced unsuccessful IVF treatment were recruited from an assisted reproduction clinic. Data were collected through in-depth interviews, using a grounded theory constructivist approach. RESULTS Of the 10 women and 4 men interviewed, 9 remained childless, 3 had adopted a child and 2 had conceived naturally. They reported gains on a personal level, interpersonal level and transpersonal level through surviving the experience of infertility. All, regardless of the eventual outcome, reported at least one form of personal gain: in personality or knowledge gain. Interpersonal gains were perceived in relationships with their spouses, children, parents, friends, colleagues and fellow IVF service users. More than half of them reported spiritual growth and a change in identity through integrating their experiences and offering help to others. CONCLUSION Despite the small sample size, this study makes a significant contribution by suggesting that while negative feelings provoked by the failure to conceive should be acknowledged, people in this situation should also be enabled to consolidate their negative experiences of IVF constructively, helping them to move on with their lives.
A search for solar-like oscillations in the Am star HD 209625

Aims. The goal is to test the structure of hot metallic stars, and in particular the structure of a near-surface convection zone using asteroseismic measurements. Indeed, stellar models including a detailed treatement of the radiative diffusion predict the existence of a near-surface convection zone in order to correctly reproduce the anomalies in surface abundances that are observed in Am stars. Methods. The Am star HD 209625 was observed with the harps spectrograph mounted on the 3.6-m telescope at the ESO La Silla Observatory (Chile) during 9 nights in August 2005. This observing run allowed us to collect 1243 radial velocity (RV) measurements ��� , with a standard deviation of 1.35 m s −1 . Results. The power spectrum associated with these RV measurements does not present any excess. Therefore, either the structure of the external layers of this star does not allow excitation of solar-like oscillations, or the amplitudes of the oscillations remain below 20–30 cm s −1 (depending on their frequency range).
How firm-specific is German apprenticeship training?

Firms participating in the German apprenticeship system do so voluntarily. Previous studies have found that on the average participating rms incur positive net cost from providing skills that appear to be easily transferable across rms. This is at variance with standard human capital theory that predicts that such training will be provided by rms operating in a com-petitve market only if workers bear all the cost of the training. This puzzle may be resolved if the training were found to be largely rm-speciic. In this paper, we try to estimate the degree to which German apprenticeship training is rm-speciic by comparing after-apprenticeship earnings of movers and stayers, as those who leave the training-rm forgo their share of any rm-speciic human capital accumulated during the apprenticeship. We obtain self-selectivity corrected estimates of the average earnings diierential by using both standard parametric as well as recently developed semiparametric techniques. On the average, we nd that there is no substantial earnings loss associated with leaving the apprenticeship rm for males. Our results provide evidence, though, for the hypothesis that the rm-speciic component of the training is considerably higher in large, industrial rms than in small rms in the crafts sector. 1 1 I am greatly indebted to Joel Horowitz and George Neumann for many helpful suggestions and disussions. Helpful comments were also made
Stereotype Accommodation: A Socio-Cognitive Perspective on Migrants’ Cultural Adaptation

Cognitive heuristics, or people’s stereotypes, are central to human interaction. Yet, the literature has been concerned with inter-ethnic stereotypes held by migrants and therefore has insufficiently addressed what might happen to individuals’ cognitive heuristics in the process of acculturating to host cultures. The authors discuss this gap in the literature by drawing on the culture learning perspective and work on cultural adaptation to examine migrants’ cognitive cultural adaptation. The concept of stereotype accommodation is introduced as a cognitive process whereby migrants incorporate the stereotype-relevant information learned in their host cultures into their preexisting stereotypes. Furthermore, a framework is presented for how cross-cultural differences, learning opportunities, individual differences, and cognitive resources might contribute to stereotype accommodation. The conclusion of this analysis is that, like any other individuals, migrants hold cognitive heuristics about varying groups in society and, moreover, these can be influenced and potentially modified by the mental short-cuts that are relevant in their host cultures.
What Makes Growth Sustained?

Abstract We identify structural breaks in economic growth in 140 countries and use these to define “growth spells:” periods of high growth preceded by an upbreak and ending either with a downbreak or with the end of the sample. Growth spells tend to be shorter in African and Latin American countries than elsewhere. We find evidence that growth duration is positively related to: the degree of equality of the income distribution; democratic institutions; export orientation (with higher propensities to export manufactures, greater openness to FDI, and avoidance of exchange rate overvaluation favorable for duration); and macroeconomic stability.
Tourism and economic growth in developing countries: P-VAR approach.

3 Abstract: This Paper examines the causality and long-run relationships between economic growth and Tourism development in developing countries using P-VAR approach during 1995-2009. The findings reveal that there is a bilateral causality and positive long-run relationship between economic growth and Tourism development. In the other words, the tourism-led growth hypothesis is confirmed, as well as, output level which relates to economic well being and level of development is important in attracting tourist.
Cortical and Trabecular Bone Benefits of Mechanical Loading Are Maintained Long Term in Mice Independent of Ovariectomy

Skeletal loading enhances cortical and trabecular bone properties. How long these benefits last after loading cessation remains an unresolved, clinically relevant question. This study investigated long‐term maintenance of loading‐induced cortical and trabecular bone benefits in female C57BL/6 mice and the influence of a surgically induced menopause on the maintenance. Sixteen‐week‐old animals had their right tibia extrinsically loaded 3 days/week for 4 weeks using the mouse tibial axial compression loading model. Left tibias were not loaded and served as internal controls. Animals were subsequently detrained (restricted to cage activities) for 0, 4, 8, 26, or 52 weeks, with ovariectomy (OVX) or sham‐OVX surgery being performed at 0 weeks detraining. Loading increased midshaft tibia cortical bone mass, size, and strength, and proximal tibia bone volume fraction. The cortical bone mass, area, and thickness benefits of loading were lost by 26 weeks of detraining because of heightened medullary expansion. However, loading‐induced benefits on bone total area and strength were maintained at each detraining time point. Similarly, the benefits of loading on bone volume fraction persisted at all detraining time points. The long‐term benefits of loading on both cortical and trabecular bone were not influenced by a surgically induced menopause because there were no interactions between loading and surgery. However, OVX had independent effects on cortical bone properties at early (4 and 8 weeks) detraining time points and trabecular bone properties at all detraining time points. These cumulative data indicate loading has long‐term benefits on cortical bone size and strength (but not mass) and trabecular bone morphology, which are not influenced by a surgically induced menopause. This suggests skeletal loading associated with physical activity may provide long‐term benefits by preparing the skeleton to offset both the cortical and trabecular bone changes associated with aging and menopause. © 2014 American Society for Bone and Mineral Research.
D ec 2 00 8 NITheP-0812 ICMPA-MPA / 2008 / 18 Noncommutative supersymmetric quantum mechanics

Supersymmetric quantum mechanics is formulated on a two dimensional noncommutative plane and applied to the supersymmetric harmonic oscillator. We find that the ordinary commutative supersymmetry is partially broken and only half of the number of supercharges are conserved. It is argued that this breaking is closely related to the breaking of time reversal symmetry arising from noncommutativity.
Polymorphisms in the endothelial nitric oxide synthase gene are associated with Behçet's disease.

OBJECTIVE Reduced plasma nitric oxide (NO) levels in Behçet's disease (BD) patients have been implicated in the development of the endothelial abnormalities and thrombotic complications occurring in these patients. This study investigated the association of the endothelial NO Synthase (eNOS) gene polymorphisms with BD. METHODS A case-control study was carried out using 193 unrelated Turkish BD patients and 106 healthy controls. All individuals were genotyped by PCR for two single-nucleotide polymorphisms (SNPs): -786 T-->C in the promoter region and 894 G-->T in exon 7 (Glu298Asp). A variable number of tandem repeats (VNTR) polymorphism in intron 4 was also investigated. RESULTS The VNTR polymorphism was associated with BD, detected by an increased frequency of the b allele (odds ratio = 1.9, P = 0.0069) and b/b genotype (odds ratio = 2.2, P = 0.002) in patients. After the stratification of cases according to the family history, a significant difference between familial cases and controls in the -786 SNP was observed, with an increase in the frequency of the T allele (odds ratio = 2.5, P = 0.0016) and T/T genotype (odds ratio = 2.5, P = 0.0085), and the association of the VNTR polymorphism with BD became stronger. The -786*T and VNTR*b alleles were in linkage disequilibrium (D' = 0.65, P <0.0001), and the number of individuals homozygous for the -786*T/VNTR*b haplotype was significantly increased in the patients. CONCLUSIONS eNOS gene polymorphisms are associated with BD, which might contribute to the reduced NO activity observed in BD patients.
Ordinal Optimization: A Large Deviations Perspective

An improved high electrical current conductive marine sweep cable. The cable includes an elongated flotation core having electrical conductors juxtaposed to the outer surface thereof with thin insulation about each of the conductors, providing high thermal conductivity therethrough. An outer jacket surrounds the associated insulated conductors and core. Structure is arranged to conduct seawater radially through the jacket for effecting heat transfer between the conductors and the ambient seawater suitable to prevent the temperature increase in the conductors resulting from the desired current flow therethrough from rising above a preselected maximum value preventing degradation of the cable.
CPU and/or GPU: Revisiting the GPU Vs. CPU Myth

Parallel computing using accelerators has gained widespread research attention in the past few years. In particular, using GPUs for general purpose computing has brought forth several success stories with respect to time taken, cost, power, and other metrics. However, accelerator based computing has signifi- cantly relegated the role of CPUs in computation. As CPUs evolve and also offer matching computational resources, it is important to also include CPUs in the computation. We call this the hybrid computing model. Indeed, most computer systems of the present age offer a degree of heterogeneity and therefore such a model is quite natural. We reevaluate the claim of a recent paper by Lee et al.(ISCA 2010). We argue that the right question arising out of Lee et al. (ISCA 2010) should be how to use a CPU+GPU platform efficiently, instead of whether one should use a CPU or a GPU exclusively. To this end, we experiment with a set of 13 diverse workloads ranging from databases, image processing, sparse matrix kernels, and graphs. We experiment with two different hybrid platforms: one consisting of a 6-core Intel i7-980X CPU and an NVidia Tesla T10 GPU, and another consisting of an Intel E7400 dual core CPU with an NVidia GT520 GPU. On both these platforms, we show that hybrid solutions offer good advantage over CPU or GPU alone solutions. On both these platforms, we also show that our solutions are 90% resource efficient on average. Our work therefore suggests that hybrid computing can offer tremendous advantages at not only research-scale platforms but also the more realistic scale systems with significant performance gains and resource efficiency to the large scale user community.
Identification and characterization of a highly motile and antibiotic refractory subpopulation involved in the expansion of swarming colonies of Paenibacillus vortex

Summary Bacteria often use sophisticated cooperative behaviours, such as the development of complex colonies, elaborate biofilms and advanced dispersal strategies, to cope with the harsh and variable conditions of natural habitats, including the presence of antibiotics. Paenibacillus vortex uses swarming motility and cell-to-cell communication to form complex, structured colonies. The modular organization of P. vortex colony has been found to facilitate its dispersal on agar surfaces. The current study reveals that the complex structure of the colony is generated by the coexistence and transition between two morphotypes – ‘builders’ and ‘explorers’ – with distinct functions in colony formation. Here, we focused on the explorers, which are highly motile and spearhead colonial expansion. Explorers are characterized by high expression levels of flagellar genes, such as flagellin (hag), motA, fliI, flgK and sigD, hyperflagellation, decrease in ATP (adenosine-5′-triphosphate) levels, and increased resistance to antibiotics. Their tolerance to many antibiotics gives them the advantage of translocation through antibiotics-containing areas. This work gives new insights on the importance of cell differentiation and task distribution in colony morphogenesis and adaptation to antibiotics.
Ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms

Cyclooxygenase (COX) 2-derived prostaglandin E(2) (PGE(2)) promotes colorectal carcinoma growth and invasion, and inhibition of COX2 by non-steroidal anti-inflammatory drugs is known to inhibit these processes. There is controversy regarding the effect of ligand activation of peroxisome proliferator-activated receptor (PPAR)-beta/delta on colon carcinogenesis, although collective evidence from independent laboratories suggest that ligand activation of PPARbeta/delta leads to the induction of terminal differentiation coupled with inhibition of cell growth in a variety of models. The present study examined the hypothesis that ligand activation of PPARbeta/delta and inhibition of COX2 attenuate colon cancer through independent mechanisms and that combining these two mechanisms will enhance this inhibition. Colon cancer was induced by administering azoxymethane to wild-type and PPARbeta/delta-null mice. Cohorts of mice were treated with GW0742 (a PPARbeta/delta ligand), nimesulide (a COX2 inhibitor) or a combination of GW0742 and nimesulide. Inhibition of COX2 by nimesulide attenuated colon cancer and ligand activation of PPARbeta/delta by GW0742 had inhibitory effects. However, the combined treatment of GW0742 and nimesulide did not cause an enhancement in the attenuation of colon cancer. Mechanistically, the effects of these compounds occurred through independent mechanisms as increased levels of differentiation markers as a result of ligand activation of PPARbeta/delta were not found with COX2 inhibition, and a reduction in PGE(2) levels resulting from COX2 inhibition was not observed in response to ligand activation of PPARbeta/delta. Results from these studies effectively dissociate COX2 inhibition and PPARbeta/delta activity during colon carcinogenesis.
Custom-designed and safe-space coaching: Australian beginning principals supported by experienced peers form pipeline of confident future leaders

ABSTRACT Transition from teacher to principal involves both a technocratic response based on ‘yearning for certainty’ that requisite leadership skills will be learned, and a critically-reflexive approach to adopting a new professional identity (Crow and Møller 2017. “Professional Identities of School Leaders across International Contexts: An Introduction and Rationale.” Educational Management and Leadership 45 (5): 749–758, 750). Globally, the maintenance of pipelines of confident and capable principals is a priority, but principal preparation programmes have often been described as decontextualised and inadequate (Cheung and Walker 2006. “Inner Worlds and Outer Limits: The Formation of Beginning School Principals in Hong Kong.” Journal of Educational Administration 44 (4): 389–407). Consequently, without opportunity to develop leadership strategies and reflect critically with a trusted mentor, newly-appointed principals often leave the role prematurely (Marks 2013. “Leadership Succession and Retention: It's Time to Get Serious about a Principal Retention Policy.” Leading and Managing 19 (2): 1–14). This Australian study aimed to evaluate the effectiveness of a Queensland Department of Education and Training coaching programme for beginning principals, designed to secure future quality leaders. A custom-built philosophy incorporated support from local master principals and a high degree of autonomy. One-on-one interviews with programme participants confirmed that: enduring professional relationships resulted from a safe-space approach; knowledge and understanding of the Australian Professional Standards for Principals (AITSL 2014. Australian Professional Standard for Principals and the Leadership Profiles. Canberra: Australian Government) increased; and feelings of empowerment and control of leadership situations accelerated. For the benefit of leadership pipelines worldwide, new principals in other contexts may be energised to continue with the complex role of being effective school leaders through similar, autonomous and peer-supported programmes.
Rethinking the Growth Diagnostics Approach: Questions from the Practitioners

The growth diagnostics methodology pioneered by Hausmann et al. (2005) is becoming a key component of the toolkit for donor agencies to formulate their operational strategies. This paper aims at clarifying the primary objectives of the approach, and at highlighting some limitations for operational use. The key to benefiting from the full potential that this approach offers lies in a proper understanding of what it does. This requires being forewarned about the indiscriminate application of the approach to any developing country, irrespective of its circumstances, for it can lead to misguided conclusions.
Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome.

BACKGROUND Human papillomavirus (HPV)-associated anogenital malignancies occur frequently in patients with human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). The purpose of our study was to determine if the high frequency of these cancers is due to lifestyle factors associated with both HPV and HIV infections or to immunosuppression following HIV infection. METHODS We studied invasive and in situ HPV-associated cancers among 309 365 U.S. patients with HIV infection/AIDS (257 605 males and 51 760 females) from 5 years before the date of AIDS onset to 5 years after this date. Sex-, race-, and age-standardized ratios of observed-to-expected cancers served as measures of relative risk (RR). Trend tests were used to evaluate changes in the RRs during the 10 years spanning AIDS onset. All statistical tests were two-sided. RESULTS All HPV-associated cancers in AIDS patients occurred in statistically significant excess compared with the expected numbers of cancers. For in situ cancers, overall risks were significantly increased for cervical (RR = 4.6; 95% confidence interval [CI] = 4.3-5.0), vulvar/vaginal (RR = 3.9; 95% CI = 2.0-7. 0), anal (in females, RR = 7.8 [95% CI = 0.2-43.6]; in males, RR = 60.1 [95% CI = 49.2-72.7]), and penile (RR = 6.9; 95% CI = 4.2-10.6) cancers, and RRs increased during the 10 years spanning AIDS onset for carcinomas in situ of the cervix (P: for trend <.001), vulva/vagina (P: for trend =.04), and penis (P: for trend =.04). For invasive cancers, overall risks were significantly increased for cervical (RR = 5.4; 95% CI = 3.9-7.2), vulvar/vaginal (RR = 5.8; 95% CI = 3.0-10.2), and anal (RR = 6.8; 95% CI = 2.7-14.0) cancers in females and for anal (RR = 37.9; 95% CI = 33.0-43.4), penile (RR = 3. 7; 95% CI = 2.0-6.2), tonsillar (RR = 2.6; 95% CI = 1.8-3.8), and conjunctival (RR = 14.6; 95% CI = 5.8-30.0) cancers in males. However, RRs for invasive cancers changed little during the 10 years spanning AIDS onset. CONCLUSIONS HPV-associated malignancies occur at increased rates in persons with HIV/AIDS. Increasing RRs for in situ cancers to and beyond the time of AIDS onset may reflect the gradual loss of control over HPV-infected keratinocytes with advancing immunosuppression. However, the lack of a similar increase for invasive HPV-associated cancers suggests that late-stage cancer invasion is not greatly influenced by immune status.
X-ray source overdensities in Chandra distant cluster fields: a new probe to map the cosmic tapestry?

The first systematic study of the serendipitous X-ray source density around 10 high z (0.24 2σ per field, and >5σ overall) only on scales 8 � × 8 � and peculiar to cluster fields. The blank field fluctuations, i.e. the most sensitive measurements to date of the X-ray cosmic variance on this scale, indicate 1σ variations within ∼15-25% around the average value. The first marginal evidence that these overdensities increase with cluster redshift is also presented. We speculate that the most likely explanation for what has been observed is that the X-ray sources are AGNs which trace filaments connected to the clusters. Nevertheless other possible explanations such as an "X-ray Butcher-Oemler" effect are not ruled out by the present results. If the association of the overdensities with large-scale structures and their positive relation with cluster redshift is confirmed, these studies could represent a new, direct, way of mapping the cosmic web and its parameters at high z.