Miracle-dz/UniFAR-FTUs huggingface dataset:
Innovation in Robotics and Pediatric Urology: Robotic Ureteroureterostomy for Duplex Systems with Ureteral Ectopia.

INTRODUCTION Robotic technology has been increasingly utilized for complicated reconstructive surgeries in pediatric urology, such as ureteroureterostomy (UU). The literature is limited regarding the performance of minimally invasive UU in children, and the existing published series utilize indwelling ureteral stents. We sought to report on our pediatric experience with robot-assisted laparoscopic (RAL)-UU using a temporary ureteral catheter in duplex systems with ureteral ectopia. METHODS A retrospective chart review was performed of all pediatric patients who underwent RAL-UU at a single institution over a 2-year period. An externalized ureteral catheter was kept overnight and removed with the indwelling catheter on postoperative day 1. Intraoperative as well as postoperative complications, length of stay (LOS), and analgesia were recorded. Follow-up renal ultrasound (US) and evaluation for symptom resolution were completed 3 months postoperatively. RESULTS Twelve patients (four male, eight female) underwent RAL-UU at a mean age of 19.4 months (range 9-48 months) during the study period. The majority of patients (83.3%) presented with hydronephrosis, and all were found to have duplicated systems with ureteral ectopia. No child had ipsilateral vesicoureteral reflux. Two children had bilateral duplicated systems, one of which required bilateral surgery. Median operative time was 138 minutes (IQR 119-180 minutes), and mean estimated blood loss was 1.5 mL. There were no intraoperative complications, and no case required open conversion. Median hospital LOS was 31 hours (IQR 30-39 hours). Median follow-up time was 11 months (range 3-22 months). One patient developed a postoperative febrile upper respiratory infection. All patients had improved hydroureteronephrosis on US at 3 months postoperatively. One patient with preoperative urinary incontinence was dry postoperatively. Therefore, the overall success rate was 100%. CONCLUSION Our institutional results demonstrate that RAL-UU utilizing a temporary ureteral catheter is a safe and effective technique for managing duplicated, ectopic ureters in children and infants.
Towards clinical assessment of velopharyngeal closure using MRI: evaluation of real-time MRI sequences at 1.5 and 3 T.

OBJECTIVE The objective of this study was to demonstrate soft palate MRI at 1.5 and 3 T with high temporal resolution on clinical scanners. METHODS Six volunteers were imaged while speaking, using both four real-time steady-state free-precession (SSFP) sequences at 3 T and four balanced SSFP (bSSFP) at 1.5 T. Temporal resolution was 9-20 frames s(-1) (fps), spatial resolution 1.6 × 1.6 × 10.0-2.7 × 2.7 × 10.0 mm(3). Simultaneous audio was recorded. Signal-to-noise ratio (SNR), palate thickness and image quality score (1-4, non-diagnostic-excellent) were evaluated. RESULTS SNR was higher at 3 T than 1.5 T in the relaxed palate (nasal breathing position) and reduced in the elevated palate at 3 T, but not 1.5 T. Image quality was not significantly different between field strengths or sequences (p=NS). At 3 T, 40% acquisitions scored 2 and 56% scored 3. Most 1.5 T acquisitions scored 1 (19%) or 4 (46%). Image quality was more dependent on subject or field than sequence. SNR in static images was highest with 1.9 × 1.9 × 10.0 mm(3) resolution (10 fps) and measured palate thickness was similar (p=NS) to that at the highest resolution (1.6 × 1.6 × 10.0 mm(3)). SNR in intensity-time plots through the soft palate was highest with 2.7 × 2.7 × 10.0 mm(3) resolution (20 fps). CONCLUSIONS At 3 T, SSFP images are of a reliable quality, but 1.5 T bSSFP images are often better. For geometric measurements, temporal should be traded for spatial resolution (1.9 × 1.9 × 10.0 mm(3), 10 fps). For assessment of motion, temporal should be prioritised over spatial resolution (2.7 × 2.7 × 10.0 mm(3), 20 fps). Advances in knowledge Diagnostic quality real-time soft palate MRI is possible using clinical scanners and optimised protocols have been developed. 3 T SSFP imaging is reliable, but 1.5 T bSSFP often produces better images.
Consumer Influences on Pirated Software Purchases: Perspectives from an Emerging Gulf Nation

This paper examines the factors that influence consumer attitude towards software purchase of pirated software in Saudi Arabia. Based on a review of literature, a model is developed that examines the personal, social, attitudinal and other factors that influence an intention to purchase pirated software. Results reveal that four social and personal factors are important in influencing consumer attitudes. Study also finds significant differences in attitude towards software purchase by buyers and non-buyers. Other findings are also reported. This research is one of the first to examine the software piracy issue in Saudi Arabia. Several practice implications are discussed.
Intravenous versus nebulized terbutaline in patients with acute severe asthma; a double-blind randomized study.

Twenty-three patients with acute severe asthma were treated in a randomized double-blind way by either intravenous terbutaline two times at an hour interval 6 micrograms/kg or inhaled terbutaline two times 0.1 mg/kg. Peak expiratory flow rate in percent of expected value rose from 89 L/min to 128 L/min (P less than .01) in the intravenous group and from 97 L/min to 122 L/min (P less than .02) in the inhalation group; this was comparable for both groups. PaO2 initially was 7.55 kPa in the intravenous group and rose by 1.4 after 60 minutes (P less than .02) and by 1.33 after 120 minutes (P less than .01). The mean PaO2 did not change in the inhalation group. The pulse rate and blood pressure did not vary significantly in either of the two groups. We conclude that both the intravenous and inhalational administration of terbutaline are effective in acute severe asthma, but that the intravenous route is possibly better for increasing PaO2.
Regulation of Expression of Microvillus Membrane Proteins by Estrogen in Baboon Fetal Ovarian Oocytes1

Abstract We previously demonstrated that the number and height of oocyte microvilli were reduced in baboon fetuses deprived of estrogen in utero and restored to normal in animals supplemented with estradiol. Phosphorylated ezrin and Na+/H+ exchange regulatory factor 1 (NHERF, now termed SLC9A3R1) link f-actin bundles to the membrane, whereas alpha-actinin cross-links f-actin to form microvilli. Therefore, we determined whether these proteins were expressed in oocytes of the fetal baboon ovary and whether expression and/or localization were altered between mid and late gestation in association with an increase in estrogen and in late gestation in animals in which estrogen was suppressed (>95%) or restored by treatment with an aromatase inhibitor with or without estradiol. Expression of alpha-actinin was low at mid gestation, increased on the surface of oocytes of primordial follicles in late gestation, and was negligible in the ovaries of estrogen-suppressed fetuses and normal in animals treated with estrogen. Ezrin (total and phosphorylated) and SLC9A3R1 expression was localized to the surface of oocytes at mid and late gestation in estrogen-replete baboons and to the cytoplasm in late gestation after estrogen suppression. These results are the first to show that the fetal baboon oocyte expressed ezrin, SLC9A3R1, and alpha-actinin, and that these proteins were localized to the oocyte surface consistent with their role in microvilli development in epithelial cells. The current study also showed that the developmental increase in oocyte expression of alpha-actinin is regulated by estrogen and correlated with the estrogen-dependent increase in oocyte microvilli demonstrated previously. Therefore, we propose that development of oocyte microvilli requires expression of alpha-actinin and that expression of alpha-actinin and localization of ezrin-phosphate and SLC9A3R1 to the oocyte membrane are regulated by estrogen.
Symposium - Market Inefficiency in Person-to-Person Betting: Examining ‘Known Loser’ Insider Trading on the Exchanges

Applying the Shin z-measure of market efficiency to the relatively new person-to-person internet betting exchanges, Smith, Paton, and Vaughan Williams found "significantly lower market biases" compared to bookmaker-dominated markets. A reduced favorite-longshot bias is interpreted as evidence that insider trading on the exchanges "is not widespread" and "not as commonplace … as is sometimes portrayed in the media. " Given that the Shin measure assumes "betting with bookies," whereas the exchanges represent "betting without bookies," the present study employs the notion of ‘significant mover’ to empirically test for the presence of ‘known loser’ insider trading on the exchanges where traditional notions of bookmaking do not apply. Findings indicate that, far from being less problematized by insider trading compared to racetrack betting, activity aimed at profiting from "known losers" may be potentially commonplace on the exchanges. This includes profiting from horses that are unplaced. This study offers new insight into the efficiency of betting markets.
Measuring E-Service Quality for Online Travel Agencies

ABSTRACT Online travel agencies face intense competition, and thus have a great need to evaluate the e-service quality of their websites to succeed or even just to survive. The present study explores the underlying dimensions used by online customers to evaluate the e-service quality of online travel agencies, as well as the relationship of these dimensions to customer satisfaction and the repurchase intention, using both qualitative and quantitative data collection techniques. Six underlying dimensions of e-service quality are identified from the results of factor analysis; namely, Website Functionality, Information Quality and Content, Fulfillment and Responsiveness, Safety and Security, Appearance and Presentation, and Customer Relationship. Furthermore, four dimensions—Website Functionality, Information Quality and Content, Safety and Security, and Customer Relationship—are found to significantly influence online customers' evaluation of overall satisfaction and their repurchase intention. The results of multiple regression analysis show Website Functionality to be the most powerful factor in predicting customer satisfaction and the repurchase intention. Implications of the study findings are discussed, and important guidelines for the development of online travel agencies are provided.
Rent Destruction and the Political Viability of Free Trade Agreements

This paper studies the political viabihty of free trade agreements (FTAs). The key element of the analysis is the "rent destruction" that these arrangements induce: by eliminating intrabloc trade barriers, an FT A lowers the incentives of import-competing industries to lobby for higher external tariffs, thereby inducing a reduction of the rents created in the lobbying process. Using a conventional competitive model, I show that the prospect of rent destruction can critically undermine (and in some cases rule out entirely) the political viability of welfare-reducing FTAs. This result contrasts sharply with findings from the earlier regionalism literature.
Topological-Insulator Passively Q-Switched Double-Clad Fiber Laser at 2  $\mu$m Wavelength

In this paper, Topological insulator (TI) Bi2Se3 as a saturable absorber (SA) is exploited to Q-switch fiber lasers at 2 μm wavelength for the first time. Few-layer TI:Bi 2Se 3 nanosheets in CS-HAc solution are prepared by the liquid-phase exfoliation method, and the thin 2-D structure with the thickness of 3-5 layers is well characterized. The open-aperture Z-scan experiment shows that the few-layer TI:Bi 2Se 3 has the saturable optical intensity of 41 MW/cm 2 at 800 nm and the modulation depth of 3.7%. The optical deposition technique is used to efficiently assemble the TI:Bi 2Se 3 nanosheets in the solution onto a fiber ferrule, therefore constructing a fiber-compatible TI-based SA (FC-TISA). By further inserting the FC-TISA into a diode-pumped Tm 3+-doped double-clad fiber laser (TM-DCFL), stable Q-switching operation at 1.98 μm is successfully achieved with the shortest pulse width of 4.18 μs and the tunable repetition rate from 8.4 to 26.8 kHz. In particular, the TM-DCFL can deliver large-energy Q-switched pulses with the pulse energy as high as 313 nJ (corresponding to average output power of 8.4 mW). Our results suggest that TI-based SA is suitable for pulsed laser operation in the eye-safe region of 2 μm, and potentially develops as an ultra-broadband photonics device.
The Changes in the Mortality Rates of Low Birth Weight Infant and Very Low Birth Weight Infant in Korea over the Past 40 Years

Total 36 reports on the mortality rates (MRs) of low birth weight infants (LBWI) and very LBWI (VLBWI) in Korea from the 1967 through 2001 were analyzed. We compared the changes in the MR by 5 and 10-yr interval. The MRs observed by 5-yr intervals from the early 1960s through the 1990s have drastically decreased. TheMRs of LBWI are as follows: 23.1% and 23.6% in the 1960s, 17.3% and 16.8% in the 1970s, 14.1% and 14.4% in the 1980s, and 8.1% in the early 1990s. The MRsof VLBWI have also fallen and were reported as follows: 68.2% and 63.7% in the 1960s, 55.8% and 57.6% in the 1970s, 56.2% and 48.1% in the 1980s, 33.5% and 24.5% in the 1990s, and 11.7% in the early 2000s. In every 10-yr period, the MRs of LBWI have decreased from 23.4% in 1960, to 17.0% in 1970, to 14.2% in 1980, and to 8.1% in 1990. The MRs of VLBWI also have decreased from 66.2% in 1960, to 56.7% in 1970, to 50.8% in 1980, to 32.9% in 1990, and to 11.7% in 2000. TheMR of LBWI and VLBWI has gone down remarkably due to improvements in neonatology in Korea as shown above.
Harvesting Productivity and Cost of Whole-Tree Clear Cutting Using a Tower Yarder in a Larix leptolepis Stand

The productivity and cost of clear cutting operations were examined to broaden our knowledge on the harvesting system in a Larix leptolepis stand of Korea. The harvesting system was divided into tree operations which were chainsaw (STIHL MS440) felling, tower yarder (Koller301-4) yarding and harvester (WOODY H50) processing. The average cycle time of felling, yarding and processing were 98 s/cycle, 245 s/cycle and 150 s/cycle. The total stump-to-pile operational productivity was 43.07 . The highest production activity was the felling 17.93 , followed by the productivity of processing 15.62 and then by the productivity of yarding 9.52 . In addition the total stump-to-pile operational cost was 24,086 . The highest cost activity was the yarding 14,557 (60.4% of the total cost), followed by the costs of processing 8,461 (35.2%) and then by the costs of felling 1,068 .
Cathepsin L affects apoptosis of glioblastoma cells: a potential implication in the design of cancer therapeutics.

BACKGROUND Previous studies indicate that Cathepsin L (CatL) is involved in brain tumour progression. Here, CatL in tumour cell invasion and apoptosis has been studied. MATERIALS AND METHODS Human glioblastoma cell line U87 was transfected with CatL cDNA in sense and antisense orientations. The in vitro invasiveness was tested in modified Boyden chambers. Apoptosis was determined by fluorescent staining, caspase activity, and by Bax and Bcl-2 mRNA levels. RESULTS Surprisingly, the invasiveness of U87 cells was not impaired by genetic down-regulation of CatL expression. In the CatL antisense clones, the apoptotic rate induced by either intrinsic or extrinsic stimuli was increased, whereas CatL sense transfection seemed to protect the cells from apoptosis. CONCLUSION Increased chemoresistance of tumour cells may be associated with increased levels of CatL and may have potential application in gene therapy, which would augment the apoptosis of glioblastoma cells induced by chemotherapy.
Spatial distribution of organic farming in Germany: does neighbourhood matter?

The spatial distribution of organic farming can be explained by combining the traditional location factors that account for spatial heterogeneity with the concept of spatial dependence. We present a theoretical model that explains a farmer's decision to convert to organic farming, and this conceptual framework is then implemented in a spatial lag model by using secondary data for Germany at the county level. The results support the assertion that agglomeration effects are important in the organic farming sector. Potential policy implications include a concentration of development measures for organic farming in certain regions. , Oxford University Press.
How Cyclical Is Bank Capital?

Using annual data since 1834 and quarterly data since 1959, I find a negative correlation between aggregate output and the bank capital ratio, though the numbers are mostly small and insignificant, even when considering leads and lags. Somewhat stronger negative correlations arise with the Tier 1 to risk-weighted assets ratio. The most significant correlations tend to reflect movements in bank assets, rather than capital itself, and although the pattern of aggregate correlations matches that of large banks, small banks show a different pattern, with strongly pro-cyclical capital ratios.
Remembrance of Things Past? The Dynamics of Organizational Forgetting

How organizations create, transfer, and retain knowledge has been the focus of intensive investigation by management researchers. However, one aspect of the dynamics of knowledge--organizational forgetting--has received comparatively little attention. In this paper, we draw on an exploratory, multiple-case study of learning in international strategic alliances to explore how and why organizations forget. Based on our case study, we develop a theory of organizational forgetting, discuss the role of forgetting in the dynamics of organizational knowledge, and present a typology of types of organizational forgetting.
China's Intellectual Property Protection Strength and its Evaluation – Based on the Accession to Trips Agreement (Agreement on Trade‐Related Aspects of Intellectual Property Rights)

This paper builds China's intellectual property protection strength from the aspects of intellectual property legislation protection strength and law enforcement protection strength, and calculates by using the actual data from 1985 to 2010. The results show that China's intellectual property protection strength has always been enhanced, and Chow test shows that the structural breakpoints appeared in China's intellectual property protection strength in 2001(when China joined TRIPS Agreement). The further Granger causality test shows that the economic development level and technological innovation ability are the factors promoting China's intellectual property protection strength, which, however, has not effectively promoted economic development and technological innovation ability due to the impact of the overall economic development level.
gerR, a Novel ger Operon Involved in l-Alanine- and Inosine-Initiated Germination of Bacillus cereus ATCC 14579

ABSTRACT Bacillus cereus endospores germinate in response to particular nutrients. Spores are able to sense these nutrients in the environment by receptors encoded by the gerA family of operons. Analysis of the Bacillus cereus ATCC 14579 genome revealed seven gerA family homologues. Using a transposon Tn917-based insertional mutagenesis approach followed by an enrichment procedure to select for l-alanine-induced germination mutants, we isolated a mutant with a defect in the l-alanine germination pathway. The transposon disrupted the last gene of a tricistronic gerA family operon, designated gerR, with the order gerRA, gerRC, gerRB. A second mutant was created by insertion of pMUTIN4 in gerRC. Both mutants showed the same phenotype for nutrient-induced germination. Spores of the gerR mutant strains were blocked in their l-alanine-initiated germination pathway and showed a delayed inosine-induced germination response. Apparently, germination mediated by l-alanine and inosine cannot be compensated for completely by the other germinant receptors, and this points towards an essential role of the gerR-encoded receptor in the receptor complex. In food products, spores of the mutant strains showed a reduced germination response compared to spores of the parental strain. High-pressure-initiated germination was not affected by the gerR mutations, as experiments with 100 and 550 MPa showed no difference with spores of the parental strain.
Initial online trust formation: the role of company location and web assurance

Purpose - Prior research suggests that significant impediments to the growth in electronic commerce exist, particularly in relation to international exchanges. This paper aims to investigate the respective roles of vendor location (domestic vs international) and web assurance seals in the development of initial trusting beliefs about a vendor's web site, and to determine whether these beliefs ultimately influence online purchase intentions. Design/methodology/approach - A model is developed and tested using a controlled laboratory experiment in which 181 subjects are randomly allocated to one of six web site treatments corresponding to two possible locations of the web site vendor (domestic vs international) and three web assurance states (no Web seal vs TRUSTe seal vs WebTrust seal). Data are analysed using ANCOVA and multiple regression analysis. Findings - As hypothesised, the results suggest that geographical location does appear to influence the formation of initial trusting beliefs (perceived trustworthiness) about a vendor's websites. In contrast, web assurance seals, in general, were found to have little influence on trusting beliefs; and accountants' seals, in particular, were found to be equally ineffective as those issued by other providers. Overall, trusting beliefs were seen to strongly influence online purchase intentions. Research limitations/implications - Future research aimed at evaluating the relative effectiveness of various trust-building mechanisms applicable to international vendors is warranted, as is research advancing the understanding of why assurance seals appear to be ineffective as trust-building mechanisms. The implications of using students as surrogates for online consumers and other limitations inherent in experimental analyses ought to be considered in interpreting the study's findings. Practical implications - The study's findings indicate that international vendors ought to consider implementing targeted trust-building mechanisms to compensate for being at a competitive disadvantage to their domestic counterparts. Suggested strategies are discussed in the paper. In relation to assurance seals, results suggest that the accounting profession can no longer assume to successfully leverage off its reputation for trustworthiness and integrity in extending its claims to expertise into new markets. Originality/value - No previous study has examined the role of vendor location in the development of initial trusting beliefs. In relation to web assurance, previous studies have produced conflicting results and employed a range of research models. This study attempts to address these concerns through the use of a comprehensive and integrated theoretical model.