Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessing the Relative Efficacy of Cognitive and Non-cognitive Factors as Predictors of Dental Anxiety European Journal of Oral Sciences

Dental fear and anxiety is one of the main barriers to the use of dental care services and in treatment compliance. The prevalence of dental anxiety is high (1–5) and it has also been found to be associated with a poorer oral health status and impaired oral health-related quality of life (6–9). Therefore, extending the knowledge of those factors that are involved in the development of dental fear should be considered a priority task. Previous research has identified some antecedents of dental fear, and the role of traumatic experiences at the dentist has received much attention as a determinant of dental fear. Several studies have found that dental fearful patients often refer to early aversive dental experiences as the origin of their treatment-related anxiety (10–13). Individual characteristics are also associated with dental anxiety. For instance, personality traits, such as neuroticism or high negative mood, as well as other anxiety disorders, have been found to be more prevalent among dental fearful patients (14). Trait anxiety also appears to predict a personÕs predisposition to dental anxiety (15). Moreover, women usually exhibit a higher level of dental anxiety than do men (4, 16–18) and gender therefore also seems to have an effect on dental anxiety. Furthermore, previous research has indicated that patientsÕ levels of dental anxiety are connected to that of their relatives (19). This finding has been proposed as a rationale for a mechanism of modelling or Ôemotional contagionÕ of dental fear among family members (20), and also as a basis for the incorporation of a genetic component in the origins of dental fear (21). Recent reasearch has highlighted the influence of cognitive factors as determinants of dental anxiety. The Cognitive Vulnerability Model (5, 22) proposes that the key point is the automatic activation of a vulnerability schema when the fearful patient is exposed to dental stimuli, although previous learning experiences and factors such as personality traits or biological dispositions may play a role in dental fear responses. The vulnerability schema comprises appraisals of the dental event as being uncontrollable, unpredictable, potentially dangerous or harmful, and disgusting. Consistent with this model, the extent to which patients perceive a lack of control during dental treatments has been repeatedly pointed out as a factor involved in dental anxiety (23, 24). Cognitive research has also identified differences in the way that dentally fearful and dentally non-fearful patients process information about dental events. Dentally anxious people …
Pressure Derivatives of Elastic Constants of Single Crystal MgO and MgAl2O4

Ultrasonic velocities of single crystal MgO (periclase) and MgAl2O4 (spinel) were measured up to 7.78 GPa and 6.16 GPa, respectively, under hydrostatic pressure. The present success was attained by making various technical developments, such as a liquid-solid hybrid system and indium bond between sample and buffer-rod. Analytical procedures were also developed both in required corrections for apparent travel times, and in formulation of pressure effect on elasticity. A distinct shear softening was found in MgAl2O4, and was predicted to occur in MgO beyond 30 GPa. Isothermal equation of state of MgO was derived by combining the present results with shock hugoniot. Heat capacity, Gruneisen constant, and coefficient of thermal expansivity of MgO at high pressures were calculated by means of a new model equation of state. Negative thermal expansivity is expected to take place in MgO above -50 GPa. The pressure derivative of rigidity of γ-Mg2SiO4 is estimated to be 0.56-1.0 by means of a lattice dynamic analogy with MgAl2O4; the lower margin of the estimate leads to the pressure-induced shear softening of γ-Mg2SiO4 in the earth's upper mantle.
Prehospital loss of R-to-R interval complexity is associated with mortality in trauma patients.

BACKGROUND To improve our ability to identify physiologic deterioration caused by critical injury, we applied nonlinear analysis to the R-to-R interval (RRI) of the electrocardiogram of prehospital trauma patients. METHODS Ectopy-free, 800-beat sections of electrocardiogram from 31 patients were identified. Twenty patients survived (S) and 11 died (NonS) after hospital admission. Demographic data, heart rate, blood pressure, field Glasgow Coma Scale (GCS) score, and survival times were recorded. RRI complexity was assessed via nonlinear statistics, which quantify entropy or fractal properties. RESULTS Age and field heart rate and blood pressure were not different between groups. Mean survival time (NonS) was 129 hours +/- 62 hours. NonS had a lower GCS score (8.6 +/- 1.7 vs. 13.2 +/- 0.8, p < 0.05). RRI approximate entropy (ApEn; 0.87 +/- 0.06 vs. 1.09 +/- 0.07, p < 0.01), sample entropy (SampEn; 0.80 +/- 0.08 vs. 1.10 +/- 0.05, p < 0.01) and fractal dimension by dispersion analysis (1.08 +/- 0.02 vs. 1.13 +/- 0.01, p < 0.05) were lower in NonS. Distribution of symbol 2 (Dis_2), a symbol-dynamics measure of RRI distribution, was higher in NonS (292.6 +/- 34.4 vs. 222 +/- 21.3, p < 0.10). For RRI data, logistic regression analysis revealed ApEn and Dis_2 as independent predictors of mortality (area under the receiver-operating characteristic curve = 0.96). When GCSMOTOR was considered, it replaced Dis_2 whereas ApEn was retained (area under curve = 0.92). When Injury Severity Score was considered, it replaced GCSMOTOR; ApEn was retained. CONCLUSIONS Prehospital loss of RRI complexity, as evidenced by decreased entropy, was associated with mortality in trauma patients independent of GCS score or Injury Severity Score.
Evening Bat Summer Roost-Site Selection on a Managed Pine Landscape

Abstract Creation and maintenance of forested corridors to increase landscape heterogeneity has been practiced for decades but is a new concept in intensively managed southern pine (Pinus spp.) forests. Additionally, more information is needed on bat ecology within such forest systems. Therefore, we examined summer roost-site selection by evening bats (Nycticeius humeralis) in an intensively managed landscape with forested corridors in southeastern South Carolina, USA, 2003–2006. We radiotracked 53 (26 M, 27 F) adult evening bats to 75 (31 M, 44 F) diurnal roosts. We modeled landscape-level roost-site selection with logistic regression and evaluated models using Akaike's Information Criterion for small samples. Model selection results indicated that mature (≥40 yr) mixed pine–hardwood stands were important roost sites for male and lactating female evening bats. Upland forested corridors, comprised of mature pine or mixed pine–hardwoods, were important roosting habitats for males and, to a lesser extent, lactating females. Male roosts were farther from open stands and lactating female roosts were farther from mid-rotation stands than randomly selected structures. Our results suggest roost structures (i.e., large trees and snags) in mature forests are important habitat components for evening bats. We recommend maintaining older (>40 yr old) stand conditions in the form of forest stands or corridors across managed landscapes to provide roosting habitat. Furthermore, our results suggest that an understanding of sex-specific roost-site selection is critical for developing comprehensive guidelines for creating and maintaining habitat features beneficial to forest bats.
Developmental Programming of Offspring Obesity, Adipogenesis, and Appetite

A newly recognized primary cause of the obesity epidemic is the developmental programming effects of infants born to mothers with obesity or gestational diabetes, intrauterine growth–restricted newborns, and offspring exposed to environmental toxins including bisphenol A. The mechanisms which result in offspring obesity include the programming of the hypothalamic appetite pathway and adipogenic signals regulating lipogenesis. Processes include nutrient sensors, epigenetic modifications, and alterations in stem cell precursors of both appetite/satiety neurons and adipocytes which are modulated to potentiate offspring obesity. Future strategies for the prevention and therapy of obesity must address programming effects of the early life environment.
Cytogenetic studies and karyotype nomenclature of three wild canid species: maned wolf (Chrysocyon brachyurus), bat-eared fox (Otocyon megalotis) and fennec fox (Fennecus zerda)

We have analysed the chromosomes of three wild and endangered canid species: the maned wolf (Chrysocyon brachyurus), the bat-eared fox (Otocyon megalotis) and the fennec fox (Fennecuszerda) using classical and molecular cytogenetic methods. For the first time detailed and encompassing descriptions of the chromosomes are presented including the chromosomal assignment of nucleolar organizer regions and the 5S rRNA gene cluster. We propose a karyotype nomenclature with ideograms including more than 300 bands per haploid set for each of these three species which will form the basis for further research. In addition, we propose four basic different patterns of karyotype organization in the family Canidae. A comparison of these patterns with the most recent molecular phylogeny of Canidae revealed that the karyotype evolution of a species is not always strongly connected with its phylogenetic position. Our findings underline the need and justification for basic cytogenetic work in rare and exotic species.
A network-based detection scheme for the jet stream core

Abstract. The polar and subtropical jet streams are strong upper-level winds with a crucial influence on weather throughout the Northern Hemisphere midlatitudes. In particular, the polar jet is located between cold arctic air to the north and warmer subtropical air to the south. Strongly meandering states therefore often lead to extreme surface weather. Some algorithms exist which can detect the 2-D (latitude and longitude) jets' core around the hemisphere, but all of them use a minimal threshold to determine the subtropical and polar jet stream. This is particularly problematic for the polar jet stream, whose wind velocities can change rapidly from very weak to very high values and vice versa. We develop a network-based scheme using Dijkstra's shortest-path algorithm to detect the polar and subtropical jet stream core. This algorithm not only considers the commonly used wind strength for core detection but also takes wind direction and climatological latitudinal position into account. Furthermore, it distinguishes between polar and subtropical jet, and between separate and merged jet states. The parameter values of the detection scheme are optimized using simulated annealing and a skill function that accounts for the zonal-mean jet stream position (Rikus, 2015). After the successful optimization process, we apply our scheme to reanalysis data covering 1979–2015 and calculate seasonal-mean probabilistic maps and trends in wind strength and position of jet streams. We present longitudinally defined probability distributions of the positions for both jets for all on the Northern Hemisphere seasons. This shows that winter is characterized by two well-separated jets over Europe and Asia (ca. 20° W to 140° E). In contrast, summer normally has a single merged jet over the western hemisphere but can have both merged and separated jet states in the eastern hemisphere. With this algorithm it is possible to investigate the position of the jets' cores around the hemisphere and it is therefore very suitable to analyze jet stream patterns in observations and models, enabling more advanced model-validation.
Spectrum of the Y=2 pentaquarks

Based on an assumed mass formula for the spectrum of the Y=2 pentaquarks, where the chromo-magnetic interaction plays an important role, and identifying the lightest state with the Θ+(1540), we predict a spectrum in good agreement with the few I=0 and I=1 candidates proposed in the past.
SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner

Androgen receptor (AR) plays an important regulatory role in prostate cancer. AR's transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications, such as SUMOylation. To study the role of AR SUMOylation in genuine chromatin environment, we compared androgen-regulated gene expression and AR chromatin occupancy in PC-3 prostate cancer cell lines stably expressing wild-type (wt) or doubly SUMOylation site-mutated AR (AR-K386R,K520R). Our genome-wide gene expression analyses reveal that the SUMOylation modulates the AR function in a target gene and pathway selective manner. The transcripts that are differentially regulated by androgen and SUMOylation are linked to cellular movement, cell death, cellular proliferation, cellular development and cell cycle. Fittingly, SUMOylation mutant AR cells proliferate faster and are more sensitive to apoptosis. Moreover, ChIP-seq analyses show that the SUMOylation can modulate the chromatin occupancy of AR on many loci in a fashion that parallels their differential androgen-regulated expression. De novo motif analyses reveal that FOXA1, C/EBP and AP-1 motifs are differentially enriched at the wtAR- and the AR-K386R,K520R-preferred genomic binding positions. Taken together, our data indicate that SUMOylation does not simply repress the AR activity, but it regulates AR's interaction with the chromatin and the receptor's target gene selection.
walk2friends: Inferring Social Links from Mobility Profiles

The development of positioning technologies has resulted in an increasing amount of mobility data being available. While bringing a lot of convenience to people's life, such availability also raises serious concerns about privacy. In this paper, we concentrate on one of the most sensitive information that can be inferred from mobility data, namely social relationships. We propose a novel social relation inference attack that relies on an advanced feature learning technique to automatically summarize users' mobility features. Compared to existing approaches, our attack is able to predict any two individuals' social relation, and it does not require the adversary to have any prior knowledge on existing social relations. These advantages significantly increase the applicability of our attack and the scope of the privacy assessment. Extensive experiments conducted on a large dataset demonstrate that our inference attack is effective, and achieves between 13% to 20% improvement over the best state-of-the-art scheme. We propose three defense mechanisms -- hiding, replacement and generalization -- and evaluate their effectiveness for mitigating the social link privacy risks stemming from mobility data sharing. Our experimental results show that both hiding and replacement mechanisms outperform generalization. Moreover, hiding and replacement achieve a comparable trade-off between utility and privacy, the former preserving better utility and the latter providing better privacy.
Spectral Domain-Optical Coherence Tomography As a New Diagnostic Marker for Idiopathic Normal Pressure Hydrocephalus

Purpose Characterized by a progressive onset of gait disturbances, dementia, and urinary incontinence, idiopathic normal pressure hydrocephalus (iNPH) is considered a rare, but under-diagnosed disease. Non-invasive diagnostic markers are still insufficient to enable the diagnosis of iNPH with certainty and yet early treatment with ventriculoperitoneal (VP) shunting can reverse symptoms and stop disease progression. Vascular circulation abnormalities in iNPH may be reflected by changes in subfoveal and peripapillary choroidal thickness (PPChT). This study uses spectral domain-optical coherence tomography (SD-OCT)-based measures of retinal and choroidal thickness to test this hypothesis and to assess ophthalmological non-invasive markers for iNPH. Methods Twelve patients who displayed neurological and neuroradiological characteristics of iNPH were subject to a full ophthalmological examination including enhanced depth imaging (EDI) SD-OCT. Of the 12 included iNPH patients, 6 had undergone VP shunting with beneficial outcome. Parameters studied with EDI SD-OCT were macular retinal thickness (MT), subfoveal choroidal thickness (SFChT), retinal nerve fiber layer thickness (RNFL), and PPChT. Results were compared with 13 healthy, age-matched controls. Results Macular thickness and RNFL and MT values of iNPH patients did not reflect atrophy. Non-shunted iNPH patients showed significantly lowered median PPChT and SFChT values compared to healthy controls. Shunted iNPH patients displayed a significantly higher median PPChT and SFChT compared to non-shunted iNPH patients. SFChT and PPChT values in shunted patients were not significantly different to values in healthy controls. Conclusion Although limited by small sample size, SD-OCT measures in this study reveal significant changes of choroidal thickness and support the hypothesis of choroidal susceptibility to hemodynamic alterations in iNPH. Non-shunted iNPH patients in this study show choroidal thinning in combination with normal RNFL and MT values. In addition to neurological and neuroradiological exams, this pattern may aid in the challenging diagnosis of iNPH.
Brain or veinoxygenation or flow? On signal physiology in functional MRI of human brain activation

Stimulus‐related signal changes in functional MRI of human brain activation not only reflect associated adjustments of cerebral blood flow and oxygen consumption, but strongly depend on the MRI technique chosen and the actual experimental setting. A list of relevant parameters includes static field homogeneity of the magnet, MR pulse sequence and signal type, TE, TR, flip angle, gradient strengths, gradient waveforms, receiver bandwidth and voxel size. In principle, a local signal increase during functional activation may reflect a regional change in cerebral blood flow or deoxyhemoglobin concentration or both. This ambiguity was demonstrated using long TE FLASH MRI at high spatial resolution. Subsequently, experimental strategies were evaluated that either discriminate MRI effects in large vessels from those in the cortical microvasculature or separate changes in blood flow velocity from those in blood oxygenation. Examples comprise studies of the human visual and motor cortex.
A Luna étale slice theorem for algebraic stacks

We prove that every algebraic stack, locally of finite type over an algebraically closed field with affine stabilizers, is etale-locally a quotient stack in a neighborhood of a point with a linearly reductive stabilizer group. The proof uses an equivariant version of Artin's algebraization theorem proved in the appendix. We provide numerous applications of the main theorems.
Increased functional coupling between the left fronto‐parietal network and anterior insula predicts steeper delay discounting in smokers

In previous work, smokers showed steeper devaluation of delayed rewards than non‐smokers. While the neural correlates of this link between nicotine dependence and delay of discounting are not established, altered activity in executive networks may relate to impaired delayed gratification. The goal of this study was to examine neural correlates of discounting and their relation to nicotine dependence. Thirty‐nine smokers and 33 non‐smokers completed a functional magnetic resonance imaging (fMRI) intertemporal choice task in which they made individualized Hard (similarly valued), easy (dissimilarly valued), and control monetary choices. FMRI data were analyzed using a group independent component analysis and dual regression. Smokers discounted more steeply than non‐smokers, although this difference was only significant among severely dependent smokers. Intertemporal choices recruited distinct left‐ and right‐lateralized fronto‐parietal networks. A group‐by‐difficulty interaction indicated that smokers, relative to non‐smokers, exhibited less difficulty‐sensitivity in the right fronto‐parietal network. In contrast, smokers showed greater functional connectivity between the left fronto‐parietal network and the left fronto‐insular cortex. Moreover, the degree of functional connectivity between the left fronto‐parietal network and left fronto‐insular cortex was significantly correlated with individual differences in discounting. Thus, greater functional coupling between the anterior insula and left fronto‐parietal network is a candidate neural substrate linking smoking and impulsivity. Given the anterior insula's role in interfacing cognitive and interoceptive processing, this altered functional connectivity may relate to an addiction‐related bias towards immediate rewards. Hum Brain Mapp 35:3774–3787, 2014. © 2014 Wiley Periodicals, Inc.
Legacies of Land Use and Recent Climatic Change: The Small Mammal Fauna in the Mountains of Utah

Climate warming will continue alongside human modification of the landscape. Therefore, studying systems modified by land use may highlight factors that mitigate or exacerbate predicted biological responses to ongoing climate warming. Using historical museum specimen records and recent field surveys, I examine temporal patterns in the ecological dynamics of the small mammal fauna on five mountain ranges in central Utah over time intervals of 27–53 years during the past century. This landscape was heavily modified by livestock grazing early in the twentieth century and since then has witnessed a steady decline in grazing intensity. In general, at regional and landscape scales, species preferring mesic habitats increased in percent abundance, rank abundance, and rank occurrence over time. This result is opposite that predicted from regional climate trends and probably represents the recovery of forest conditions following a release over time from earlier periods of severe overgrazing. Decreased grazing intensity may thus mitigate the predicted biological effects of climatically driven environmental change for small mammals. This work also illustrates that abundance data gleaned from natural history collections can be an appropriate tool for assessing temporal changes in composition, especially when comparisons are drawn using time‐ and space‐averaged data sets.
Isotope shift in the electron affinity of chlorine.

The specific mass shift in the electron affinity between $^{35}\mathrm{Cl}$ and $^{37}\mathrm{Cl}$ has been determined by tunable-laser photodetachment spectroscopy to be -0.51(14) GHz. The isotope shift was observed as a difference in the onset of the photodetachment process for the two isotopes. In addition, the electron affinity of Cl was found to be 29 138.59(22) ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$, giving a factor of 2 improvement in the accuracy over earlier measurements. Many-body calculations including lowest-order correlation effects demonstrate the sensitivity of the specific mass shift and show that the inclusion of higher-order correlation effects would be necessary for a quantitative description.