Miracle-dz/UniFAR-FTUs huggingface dataset:
The sound of a mobile phone ringing affects the complex reaction time of its owner

Introduction Mobile phone conversation decreases the ability to concentrate and impairs the attention necessary to perform complex activities, such as driving a car. Does the ringing sound of a mobile phone affect the driver's ability to perform complex sensory-motor activities? We compared a subject's reaction time while performing a test either with a mobile phone ringing or without. Material and methods The examination was performed on a PC-based reaction time self-constructed system Reactor. The study group consisted of 42 healthy students. The protocol included instruction, control without phone and a proper session with subject's mobile phone ringing. The terms of the study were standardised. Results There were significant differences (p < 0.001) in reaction time in control (597 ms), mobile (633 ms) and instruction session (673 ms). The differences in female subpopulation were also significant (p < 0.01). Women revealed the longest reaction time in instruction session (707 ms), were significantly quicker in mobile (657 ms, p < 0.01) and in control session (612 ms, p < 0.001). In men, the significant difference was recorded only between instruction (622 ms) and control session (573 ms, p < 0.01). The other differences were not significant (p > 0.08). Men proofed to complete significantly quicker than women in instruction (p < 0.01) and in mobile session (p < 0.05). Differences amongst the genders in control session was not significant (p > 0.05). Conclusions The results obtained proofed the ringing of a phone exerts a significant influence on complex reaction time and quality of performed task.
Social Functioning, Victimization, and Mental Health among Female Offenders

Females who have experienced victimization or abuse during childhood tend to have poorer outcomes in adulthood with regard to criminal behavior, mental health, and social relationships. Although scholars have hypothesized that female offenders may benefit from programming that emphasizes empowerment and healthy relationships, empirical examination of this idea remains limited. Using a sample of 300 female offenders, this study empirically explored whether a history of victimization is a risk factor for future mental health problems and criminal behavior, and whether positive social functioning serves as a protective factor for females with histories of victimization. The results indicated that victimization history in this sample may not be associated with recidivism risk but with vulnerability to stress and mental health problems. In addition, the presence of social resources such as education and noncriminal friends appeared to act as a buffer against stress experienced as a result of life events.
Extended-Release Mixed Amphetamine Salts vs Placebo for Comorbid Adult Attention-Deficit/Hyperactivity Disorder and Cocaine Use Disorder: A Randomized Clinical Trial.

IMPORTANCE Adult attention-deficit/hyperactivity disorder (ADHD) is prevalent but often unrecognized, in part because it tends to co-occur with other disorders such as substance use disorders. Cocaine use disorder is one such disorder with high co-occurrence of ADHD. OBJECTIVE To examine whether treatment of co-occurring ADHD and cocaine use disorder with extended-release mixed amphetamine salts is effective at both improving ADHD symptoms and reducing cocaine use. DESIGN, SETTING, AND PARTICIPANTS Thirteen-week, randomized, double-blind, 3-arm, placebo-controlled trial of participants meeting DSM-IV-TR criteria for both ADHD and cocaine use disorder conducted between December 1, 2007, and April 15, 2013, at 2 academic health center substance abuse treatment research sites. One hundred twenty-six adults diagnosed as having comorbid ADHD and cocaine use disorder were randomized to extended-release mixed amphetamine salts or placebo. Analysis was by intent-to-treat population. INTERVENTIONS Participants received extended-release mixed amphetamine salts (60 or 80 mg) or placebo daily for 13 weeks and participated in weekly individual cognitive behavioral therapy. MAIN OUTCOMES AND MEASURES For ADHD, percentage of participants achieving at least a 30% reduction in ADHD symptom severity, measured by the Adult ADHD Investigator Symptom Rating Scale; for cocaine use, cocaine-negative weeks (by self-report of no cocaine use and weekly benzoylecgonine urine screens) during maintenance medication (weeks 2-13) and percentage of participants achieving abstinence for the last 3 weeks. RESULTS More patients achieved at least a 30% reduction in ADHD symptom severity in the medication groups (60 mg: 30 of 40 participants [75.0%]; odds ratio [OR] = 5.23; 95% CI, 1.98-13.85; P < .001; and 80 mg: 25 of 43 participants [58.1%]; OR = 2.27; 95% CI, 0.94-5.49; P = .07) compared with placebo (17 of 43 participants [39.5%]). The odds of a cocaine-negative week were higher in the 80-mg group (OR = 5.46; 95% CI, 2.25-13.27; P < .001) and 60-mg group (OR = 2.92; 95% CI, 1.15-7.42; P = .02) compared with placebo. Rates of continuous abstinence in the last 3 weeks were greater for the medication groups than the placebo group: 30.2% for the 80-mg group (OR = 11.87; 95% CI, 2.25-62.62; P = .004) and 17.5% for the 60-mg group (OR = 5.85; 95% CI, 1.04-33.04; P = .04) vs 7.0% for placebo. CONCLUSIONS AND RELEVANCE Extended-release mixed amphetamine salts in robust doses along with cognitive behavioral therapy are effective for treatment of co-occurring ADHD and cocaine use disorder, both improving ADHD symptoms and reducing cocaine use. The data suggest the importance of screening and treatment of ADHD in adults presenting with cocaine use disorder. TRIAL REGISTRATION clinicaltrials.gov Identifier:NCT00553319.
Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease

The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson's disease. The question is an important one because synchronization will increase postsynaptic efficacy at subsequent projection targets. We simultaneously recorded local potentials (LPs) from the globus pallidus interna (GPi) and subthalamic nucleus (STN) in four awake patients after neurosurgery for Parkinson's disease. Nuclei from both sides were recorded in two patients so that a total of six ipsilateral GPi–STN LP recordings were made. Without medication, the power within and the coherence between the GPi and STN was dominated by activity with a frequency <30 Hz. Treatment with the dopamine precursor levodopa reduced the low-frequency activity and resulted in a new peak at ∼70 Hz. This was evident in the power spectrum from STN and GPi and in the coherence between these nuclei. The phase relationship between the nuclei varied in a complex manner according to frequency band and the presence of exogenous dopaminergic stimulation. Synchronization of activity does occur between pallidum and STN, and its pattern is critically dependent on the level of dopaminergic activity.
Polymorphisms in the DNA Repair Gene XRCC 1 and Breast Cancer 1

X-ray repair cross complementing group 1 (XRCC1) encodes a protein involved in base excision repair. We examined the association of polymorphisms inXRCC1 (codon 194 Arg3Trp and codon 399 Arg3Gln) and breast cancer in the Carolina Breast Cancer Study, a populationbased case-control study in North Carolina. No association was observed betweenXRCC1codon 194 genotype and breast cancer, and odds ratios (ORs) were not modified by smoking or radiation exposure. A positive association for XRCC1codon 399 Arg/Gln or Gln/Gln genotypes compared with Arg/Arg was found among African Americans (253 cases, 266 controls; OR5 1.7, 95% confidence interval, 1.1– 2.4) but not whites (386 cases, 381 controls; OR51.0, 95% confidence interval, 0.8–1.4). Among African-American women, ORs for the duration of smoking were elevated among women withXRCC1codon 399 Arg/Arg genotype (trend test; P < 0.001) but not Arg/Gln or Gln/Gln (P 5 0.23). There was no difference in OR for smoking according to XRCC1codon 399 genotype in white women. ORs for occupational exposure to ionizing radiation were stronger for African-American and white women with codon 399 Arg/Arg genotype. High-dose radiation to the chest was more strongly associated with breast cancer among white women with XRCC1codon 399 Arg/Arg genotype. Our results suggest thatXRRC1codon 399 genotype may influence breast cancer risk, perhaps by modifying the effects of environmental exposures. However, interpretation of our results is limited by incomplete knowledge regarding the biological function of XRCC1alleles.
Acute effect of the proprioceptive neuromuscular facilitation method on vertical jump performance

Acute effect of the proprioceptive neuromuscular facilitation method on vertical jump performance Study aim: To assess the acute effect of the proprioceptive neuromuscular facilitation method (PNF) on the explosive strength of lower extremities of male soldiers. Material and methods: A group of 26 male soldiers performed two exercise sessions on different days, in a random order: without stretching (control exercise) or by applying PNF (experimental exercise). Before and after the PNF (0, 10, 20, 40 and 60 min), 3 vertical counter-movement jumps on a tensometric platform were executed. Results: CMJ results in the experimental sessions were significantly (p<0.001) decreased after the PNF exertion in relation to the initial (pre-session) value. No significant post-session decreases were found in the control exercise. However, the differences between the experimental and control results were significant (p<0.05) only immediately after the PNF exertion and 10 min later. Conclusion: The PNF method negatively affects the vertical jump performance and, thus, ought not to be used as part of warm-ups.
Weight-of-the-evidence evaluation of 2,4-D potential for interactions with the estrogen, androgen and thyroid pathways and steroidogenesis

Abstract A comprehensive weight-of-the-evidence evaluation of 2,4-dichlorophenoxyacetic acid (2,4-D) was conducted for potential interactions with the estrogen, androgen and thyroid pathways and with steroidogenesis. This assessment was based on an extensive database of high quality in vitro, in vivo ecotoxicological and in vivo mammalian toxicological studies. Epidemiological studies were also considered. Toxicokinetic data provided the basis for determining rational cutoffs above which exposures were considered irrelevant to humans based on exceeding thresholds for saturation of renal clearance (TSRC); extensive human exposure and biomonitoring data support that these boundaries far exceed human exposures and provide ample margins of exposure. 2,4-D showed no evidence of interacting with the estrogen or androgen pathways. 2,4-D interacts with the thyroid axis in rats through displacement of thyroxine from plasma binding sites only at high doses exceeding the TSRC in mammals. 2,4-D effects on steroidogenesis parameters are likely related to high-dose specific systemic toxicity at doses exceeding the TSRC and are not likely to be endocrine mediated. No studies, including high quality studies in the published literature, predict significant endocrine-related toxicity or functional decrements in any species at environmentally relevant concentrations, or, in mammals, at doses below the TSRC that are relevant for human hazard and risk assessment. Overall, there is no basis for concern regarding potential interactions of 2,4-D with endocrine pathways or axes (estrogen, androgen, steroidogenesis or thyroid), and thus 2,4-D is unlikely to pose a threat from endocrine disruption to wildlife or humans under conditions of real-world exposures.
A new Bayesian lower bound on the mean square error of estimators

In this paper, the Weiss-Weinstein family of Bayesian lower bounds on the mean-square-error of estimators is extended to an integral form. A new class of Bayesian lower bounds is derived from this integral form by approximating each entry of the vector of estimation error in a closed Hilbert subspace of L2. This Hilbert subspace is spanned by a set of linear transformations of elements in the domain of an integral transform of a particular function, which is orthogonal to any function of the observations. It is shown that new Bayesian bounds can be derived from this class by selecting the particular function from a known set and modifying the kernel of the integral transform. A new computationally manageable lower bound is derived from the proposed class using the kernel of the Fourier transform. The bound is computationally manageable and provides better prediction of the signal-to-noise ratio threshold region, exhibited by the maximum a-posteriori probability estimator. The proposed bound is compared with other known bounds in terms of threshold SNR prediction in the problem of frequency estimation.
Association of Parity and Time since Last Birth with Breast Cancer Prognosis by Intrinsic Subtype

Background: Parity and time since last birth influence breast cancer risk and vary by intrinsic tumor subtype, but the independent effects of these factors on prognosis have received limited attention. Methods: Study participants were 1,140 invasive breast cancer patients from phases I and II of the population-based Carolina Breast Cancer Study, with tissue blocks available for subtyping using immunohistochemical markers. Breast cancer risk factors, including pregnancy history, were collected via in-person interviews administered shortly after diagnosis. Vital status was determined using the National Death Index. The association of parity and birth recency with breast cancer–specific and overall survival was assessed using Cox proportional hazards models. Results: During follow-up (median = 13.5 years), 450 patients died, 61% due to breast cancer (n = 276). High parity (3+ births) and recent birth (<5 years before diagnosis) were positively associated with breast cancer–specific mortality, independent of age, race, and selected socioeconomic factors [parity, reference = nulliparous, adjusted HR = 1.76; 95% confidence interval (CI) = 1.13–2.73; birth recency, reference = 10+ years, adjusted HR = 1.29; 95% CI, 0.79–2.11]. The associations were stronger among patients with luminal tumors and those surviving longer than 5 years. Conclusions: Parity and recent birth are associated with worse survival among breast cancer patients, particularly among luminal breast cancers and long-term survivors. Impact: The biologic effects of parity and birth recency may extend from etiology to tumor promotion and progression. Cancer Epidemiol Biomarkers Prev; 25(1); 60–67. ©2015 AACR.
Reasoning about Conditional Promises and Warnings: Darwinian Algorithms, Mental Models, Relevance Judgements or Pragmatic Schemas?

It is proposed that reasoning about social contracts, such as conditional promises and warnings, is under the control of a compound schema made of two pragmatic schemas (Cheng & Holyoak, 1985), expressing an obligation and a permission. Two experiments were run using thematic versions of the Wason selection task in which the rule and the core of the scenario were kept constant and the point of view of the actor (e.g. promisor or promisee) was varied. The results supported the predictions (including the occurrence of a correct pattern of response that consists of all four cards) and falsified predictions derived from Cosmides' (1989) theory of social exchange. The mental models theory and Evans' two-stage theory of reasoning are also discussed in the light of the present results.
Testing Interval Independence Versus Configural Weighting Using Judgments of Strength of Preference

Judges made choices and raced strengths of preference between gambles composed of 50-50 chances to receive either of 2 monetary outcomes (x, y). Others judged how much they would pay to play their chosen gamble rather than the other gamble. Judged strengths of preference violated interval independence, because they depended on the value of a common outcome. For example, judges offered to pay an average of $44 to play ($74, $100) instead of ($8, $100) but offered to pay only $24 to play ($6, $74) instead of ($6, $8). Results violated the theory that utility of gambles is a nonconfigural average of the values of the outcomes and that strengths of preference are monotonically related to utility differences. Results can be explained by a configural weight model in which the lowest outcome receives greater weight.
Some developmental patterns in the speech of 6-, 8- and 10-year old children: an acoustic phonetic study

The process of the development of fine motor speech skills co-occurs with the maturation of the vocal apparatus. This brief study presents some acoustic phonetic characteristics of the speech of twenty pre-adolescent (6-, 8- and 10-year-olds) boys and girls. The speech data were elicited via a picture-naming task. Both age and sex differences in the acoustic phonetic characteristics of selected vowels and consonants are examined. The acoustic phonetic characteristics that were investigated included formant frequency values and coarticulation (or gestural overlap) patterns. Age, sex and age-by-sex differences for the acoustic phonetic characteristics are presented and discussed for the data with reference to speech development and the sexual dimorphism of the vocal apparatus.
Very Deep Convolutional Networks for Natural Language Processing

The dominant approach for many NLP tasks are recurrent neural networks, in particular LSTMs, and convolutional neural networks. However, these architectures are rather shallow in comparison to the deep convolutional networks which are very successful in computer vision. We present a new architecture for text processing which operates directly on the character level and uses only small convolutions and pooling operations. We are able to show that the performance of this model increases with the depth: using up to 29 convolutional layers, we report significant improvements over the state-of-the-art on several public text classification tasks. To the best of our knowledge, this is the first time that very deep convolutional nets have been applied to NLP.
Self‐determination within Australian school transition programmes for students with a disability

The concept of self‐determination has gained prominence over recent years in parallel with the recognition of the rights of people with a disability. Services are being pressured to make radical changes to the restrictive philosophies and practices of the past. This paper reviews seven Australian transition programmes for young people with disabilities as they moved from school to adult options. It examines the extent to which self‐determination principles are evident and whether they led to a wider range of opportunities and a reshaping of the service system. The studies showed that participation in decision‐making by young people and their families resulted in increased service responsiveness and greater achievement of preferred outcomes. However, the restructuring of service systems to become more flexible and responsive has been slower than expected. One contributing factor appears to be that an increasing demand for resources creates pressures for more bureaucratic and less person‐oriented approaches.
Sensitivity of inverse estimation of annual mean CO2 sources and sinks to ocean‐only sites versus all‐sites observational networks

Inverse estimation of carbon dioxide (CO2) sources and sinks uses atmospheric CO2 observations, mostly made near the Earth's surface. However, transport models used in such studies lack perfect representation of atmospheric dynamics and thus often fail to produce unbiased forward simulations. The error is generally larger for observations over the land than those over the remote/marine locations. The range of this error is estimated by using multiple transport models (16 are used here). We have estimated the remaining differences in CO2 fluxes due to the use of ocean‐only versus all‐sites (i.e., over ocean and land) observations of CO2 in a time‐independent inverse modeling framework. The fluxes estimated using the ocean‐only networks are more robust compared to those obtained using all‐sites networks. This makes the global, hemispheric, and regional flux determination less dependent on the selection of transport model and observation network.
The Effects of Perceived Management Concern for Frontline Employees and Customers on Turnover Intentions

This study develops and tests a turnover intentions model, which examines the effects of frontline employees' perceptions of management concern for employees and customers on turnover intentions, mediated by job satisfaction and affective organizational commitment. Using this model as a framework, the authors explore the role of employment status (full-time vs. part-time) as a moderator of the aforementioned relationships. The results indicate that perceived management concern for employees and customers has significant effects on employees' turnover intentions. Employment status moderates the relationships between perceived management concern for employees and affective organizational commitment, perceived management concern for customers and job satisfaction, and affective organizational commitment and turnover intentions. Implications of the findings are discussed and future research avenues are offered.
Forty-five years of schizophrenia: personal reflections

Views about schizophrenia can change dramatically, even within one lifetime. In order to illustrate such changes over the last forty-five years, this article uses the example of ‘Mandy’, a composite woman patient with a diagnosis of schizophrenia. It shows that, although there have been many advances over this period, understanding of schizophrenia continues to be elusive, and treatments remain imperfect. Therefore, as perspectives shift and the ground moves beneath us, the psychiatric profession needs to anchor itself firmly in the stories our patients tell us.
Mental Health and Suicidal Behaviours in LGBTI Populations and Access to Care in Australia : A Literature Review

There is evidence for greater vulnerability to various mental health issues among lesbian, gay, bisexual, transgender, and intersex (LGBTI) people in Australia, depression, anxiety, and suicidal behaviours in particular. There is therefore a gap in addressing the psychological distress of LGBTI people, who experience disproportionately negative mental health outcomes in comparison with the general community, yet despite these poorer outcomes, are less likely to seek help than their mainstream counterparts (beyondblue, 2014). There are also clear barriers to change, including discrimination, social exclusion and isolation, reluctance to access help, and the failure of generic health interventions and prevention strategies to be inclusive of LGBTI people and their needs (Rosenstreich, 2013). Currently, the idea that treating everyone the same is best practice constitutes the biggest barrier to change in LGBTI mental health and recent Australian research demonstrates that such a policy reinforces the current situation and that this approach is not enough (Barrett & Stephens, 2012).
Partial product reduction based on look-up tables

In this paper a new technique for partial product reduction based on the use of look-up tables for efficient processing is presented. We describe how to construct counter devices with pre-calculated data and their subsequent integration into the whole operation. The development of reduction trees organizations for this kind of devices uses the inherent integration benefits of computer memories and offers an alternative implementation to classic operation methods. Therefore, in our experiments we compare our implementation model with CMOS technology model in homogeneous terms.