Miracle-dz/UniFAR-FTUs huggingface dataset:
Benefits of recovery after work among Turkish manufacturing managers and professionals

Purpose – A body of research evidence has shown that job stressors are associated with lower levels of satisfaction and psychological well‐being. It has been suggested that recovery after the work day may reduce fatigue, restore mood and improve well‐being. The purpose of this paper is to examine predictors and consequences of four recovery experiences (psychological detachment, relaxation, mastery, and control) identified by Sonnentag and Fritz, to replicate and extend their work.Design/methodology/approach – Data were collected from 887 men and women managers and professionals working in the manufacturing sector in Turkey using anonymously completed questionnaires (a 58 percent response rate). Findings – Respondents at higher organizational levels made more use of both mastery and control. Personality factors (need for achievement and workaholism components) were also positively correlated with use of mastery and control. Hierarchical regression analyses controlling both personal demographic and work sit.
Changing Differences by Educational Attainment in Fathers’ Domestic Labour and Child Care

In understanding processes of change in family work, examining differences in the degree of change between different social groups (‘changing differences’) can be more informative than focusing either on overall changes or on cross-sectional differences by social group alone. British and US time-use data sets are used to examine 30-year changes in men’s contribution to domestic work and child care by differences in educational attainment. Changes are compared for fathers in dual-earner couples with different levels of education. The findings illustrate two contrasting changing differences: a ‘catch-up’ effect over time between fathers with different educational attainment in the case of domestic labour; and in the case of child care, a widening of the gap by education. The challenges posed by these changing differences for common structural explanations of change in family work are discussed.
MLbase: A Distributed Machine-learning System

Machine learning (ML) and statistical techniques are key to transforming big data into actionable knowledge. In spite of the modern primacy of data, the complexity of existing ML algorithms is often overwhelming|many users do not understand the trade-os and challenges of parameterizing and choosing between dierent learning techniques. Furthermore, existing scalable systems that support machine learning are typically not accessible to ML researchers without a strong background in distributed systems and low-level primitives. In this work, we present our vision for MLbase, a novel system harnessing the power of machine learning for both end-users and ML researchers. MLbase provides (1) a simple declarative way to specify ML tasks, (2) a novel optimizer to select and dynamically adapt the choice of learning algorithm, (3) a set of high-level operators to enable ML researchers to scalably implement a wide range of ML methods without deep systems knowledge, and (4) a new run-time optimized for the data-access patterns of these high-level operators.
Introduction to the neurophysiological study of sleep: central regulation of skeletal and ocular activities.

This paper investigates the historical evolution of the major experimental results in the field of the central mechanisms underlying the skeletal motor activities and the eye movements during sleep. First, the neurophysiological background of paradoxical sleep atonia and paradoxical sleep without atonia was examined. Then, the analysis was directed to the eye movements in humans and animals, their central command processes and their correlative electrophysiological activities: ponto-geniculo-occipital waves and eye movement potentials.
Increased chemosensitivity and radiosensitivity of human breast cancer cell lines treated with novel functionalized single-walled carbon nanotubes

Hypoxia is a major cause of treatment resistance in breast cancer. Single-walled carbon nanotubes (SWCNTs) exhibit unique properties that make them promising candidates for breast cancer treatment. In the present study, a new functionalized single-walled carbon nanotube carrying oxygen was synthesized; it was determined whether this material could increase chemosensitivity and radiosensitivity of human breast cancer cell lines, and the underlying mechanisms were investigated. MDA-MB-231 cells growing in folic acid (FA) free medium, MDA-MB-231 cells growing in medium containing FA and ZR-75-1 cells were treated with chemotherapy drugs or radiotherapy with or without tombarthite-modified-FA-chitosan (R-O2-FA-CHI)-SWCNTs under hypoxic conditions, and the cell viability was determined by water-soluble tetrazolium salts-1 assay. The cell surviving fractions were determined by colony forming assay. Cell apoptosis induction was monitored by flow cytometry. Expression of B-cell lymphoma 2 (Bcl-2), survivin, hypoxia-inducible factor 1-α (HIF-1α), multidrug resistance-associated protein 1 (MRP-1), P-glycoprotein (P-gp), RAD51 and Ku80 was monitored by western blotting. The novel synthesized R-O2-FA-CHI-SWCNTs were able to significantly enhance the chemosensitivity and radiosensitivity of human breast cancer cell lines and the material exhibited its expected function by downregulating the expression of Bcl-2, survivin, HIF-1α, P-gp, MRP-1, RAD51 and Ku80.
Beneficial Role of Antioxidants on Clinical Outcomes and Erythrocyte Antioxidant Parameters in Rheumatoid Arthritis Patients

Background: This study aims to investigate the effect of antioxidants supplement on clinical outcomes and antioxidant parameters in rheumatoid arthritis (RA). Methods: The pre-post study was conducted on 40 female patients with RA in 12 weeks that taken daily one Selenplus capsule contained 50 μg selenium, 8 mg zinc, 400 μg vitamin A, 125 mg vitamin C, and 40 mg vitamin E. About 5 mL venous blood sample was taken from all participants and disease activity score (DAS) was determined by DAS-28 formula and high-sensitive C-reactive protein (hs-CRP). Glutathione peroxidase (GPX) and superoxide dismutase (SOD) were measured by spectrophotometric kit and catalase (CAT) was measured by Abei method. Total antioxidant capacity (TAC) was determined by spectrophotometric kit. Distribution of the variables was assessed using histogram with normal curve as well as Kolmogorov-Smirnov test and data were analyzed with paired t-test for differences between pre-post data using SPSS software version 13.5. Conclusions: Our findings showed that antioxidants may improve disease activity significantly, but it did not affect the number of painful and swollen joints and increased erythrocyte antioxidant levels. Antioxidants may be useful for controlling of clinical outcomes and oxidative stress in RA.
You cope by breaking down in private: fathers and Ptsd following childbirth

Literature on birth trauma has focused on women's experiences and the evidence of post-traumatic stress disorder (PTSD) following childbirth. For some fathers witnessing a traumatic birth involving their partner and/or baby, symptoms of post-traumatic stress disorder may also be apparent. In this New Zealand study descriptive phenomenology was used to explore the phenomenon of post-traumatic stress following childbirth as twenty-one fathers narrated their experiences of witnessing a traumatic birth. Four themes encapsulated their experiences: it's not a spectator sport; it's about being included; it's sexual scarring; it's toughing it out. These results demonstrate that some men are left with a negative emotional experience that has serious consequences for their relationships and families. Midwives should be aware that many men have ambiguous expectations about being at the birth. If fathers are witness to a traumatic birth, as they perceive it, they need resolution.
Home divided, home reconstructed: children in rural–urban migration in contemporary China†

This article is centred on the geographies of Chinese children in contemporary China – an area which has been problematically overlooked in geographical literature on childhood. In employing unique mobile research methods by tracking migrant children through the migration cycle, the author conducted an extensive ethnographic study of rural migrant children aged 8–17 in China. The article explores rural children's everyday lived experience of migration and how migrant children negotiate and articulate home and belonging while on the move. The study demonstrates the dynamic environment that migrant children inhabit, the fluid, contextual and mobile nature of their life in rural migrant households, their migrancy and their active involvement in homemaking.
EMDR: An Evidence-Based Treatment for Victims of Trauma

Abstract More than half of the United States population has been affected by psychological trauma. Many individuals who survive traumatic experiences develop post-traumatic stress disorder (PTSD) and related psychological problems. Eye Movement Desensitization and Reprocessing (EMDR) is an effective treatment for such disorders. EMDR focuses on reprocessing the dysfunctionally stored memories of the traumatic experience, enabling the client to progress through appropriate stages of affect and insight to reach an adaptive resolution regarding critical issues such as personal responsibility, safety in the present, and the availability of choices in the future. This article describes EMDR, discusses studies of its effectiveness, and concludes with recommendations for trauma-related policy and practice.
Penalized logistic regression for high-dimensional DNA methylation data with case-control studies

MOTIVATION DNA methylation is a molecular modification of DNA that plays crucial roles in regulation of gene expression. Particularly, CpG rich regions are frequently hypermethylated in cancer tissues, but not methylated in normal tissues. However, there are not many methodological literatures of case-control association studies for high-dimensional DNA methylation data, compared with those of microarray gene expression. One key feature of DNA methylation data is a grouped structure among CpG sites from a gene that are possibly highly correlated. In this article, we proposed a penalized logistic regression model for correlated DNA methylation CpG sites within genes from high-dimensional array data. Our regularization procedure is based on a combination of the l(1) penalty and squared l(2) penalty on degree-scaled differences of coefficients of CpG sites within one gene, so it induces both sparsity and smoothness with respect to the correlated regression coefficients. We combined the penalized procedure with a stability selection procedure such that a selection probability of each regression coefficient was provided which helps us make a stable and confident selection of methylation CpG sites that are possibly truly associated with the outcome. RESULTS Using simulation studies we demonstrated that the proposed procedure outperforms existing main-stream regularization methods such as lasso and elastic-net when data is correlated within a group. We also applied our method to identify important CpG sites and corresponding genes for ovarian cancer from over 20 000 CpGs generated from Illumina Infinium HumanMethylation27K Beadchip. Some genes identified are potentially associated with cancers.
Teachers' understandings of forgiveness in a troubled society: an empirical exploration and implications for forgiveness pedagogies

The purpose of this article is to explore how teachers define forgiveness in a society troubled with political conflict and historical trauma, what reservations they have and what pedagogical opportunities (if any) are created to teach about/for forgiveness in schools. More specifically, this is a phenomenological study of how a group of Greek-Cypriot teachers who teach in a troubled society (Cyprus) understand forgiveness; the authors examine how forgiveness pedagogies might or might not become part of Greek-Cypriot curricula and teaching practices. This article shows that some forgiveness pedagogies will not take place in schools unless there is political settlement in Cyprus. This finding does not preclude the possibility of engaging in some forms of forgiveness pedagogies before reconciliation is reached; however, these pedagogies will vary widely in value, depending on their context and motivation. An important contribution of forgiveness pedagogies is the creation of learning spaces which restore the humanness that is often lost in troubled societies.
Recipient‐derived angiogenesis with short term immunosuppression increases bone remodeling in bone vascularized composite allotransplantation: A pilot study in a swine tibial defect model

Current vascularized composite allotransplantation (VCA) transplantation protocols rely upon life‐long immune modulation to maintain tissue perfusion. Alternatively, bone‐only VCA viability may be maintained in small animal models using surgical angiogenesis from implanted autogenous vessels to develop a neoangiogenic bone circulation that will not be rejected. This study tests the method's efficacy in a large animal model as a bridge to clinical practice, quantifying the remodeling and mechanical properties of porcine tibial VCAs. A segmental tibial defect was reconstructed in Yucatan miniature swine by transplantation of a matched tibia segment from an immunologically mismatched donor. Microsurgical repair of nutrient vessels was performed in all pigs, with simultaneous intramedullary placement of an autogenous arteriovenous (AV) bundle in Group 2. Group 1 served as a no‐angiogenesis control. All received 2 weeks of immunosuppression. After 16 weeks, micro‐CT and histomorphometric analyses were used to evaluate healing and remodeling. Axial compression and nanoindentation studies evaluated bone mechanical properties. Micro‐CT analysis demonstrated significantly more new bone formation and bone remodeling at the distal allotransplant/recipient junction and on the endosteal surfaces of Group 2 tibias (p = 0.03). Elastic modulus and hardness were not adversely affected by angiogenesis. The combination of 2 weeks of immunosuppression and autogenous AV‐bundle implantation within a microsurgically transplanted tibial allotransplant permitted long‐term allotransplant survival over the study period of 16 weeks in this large animal model. Angiogenesis increased bone formation and remodeling without adverse mechanical effects. The method may allow future composite‐tissue allotransplantation of bone without the risks associated with long‐term immunosuppression. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1242–1249, 2017.
Calculation Method for the Three-Dimensional Ising Ferromagnet Thermodynamics within the Frames of $\rho^6$ Model

Calculation of thermodynamic functions of the three-dimensional Ising ferromagnet above and below critical temperature is performed in the approximation of sixfold basis distribution ($\rho^6$ model). Comparison with the results for the $\rho^4$ model indicates that dependence of the thermodynamic functions on the renormalization group parameter $s$ becomes weaker. The optimal interval of the renormalization group parameter values is determined.
Illness Labels and Social Distance

The authors examine a key proposition in the modified labeling theory—that a psychiatric label increases vulnerability to negative evaluation and social rejection—using an experimental design wherein female participants interact with a female teammate over a computer. The authors also evaluate a hypothesis derived from the disease-avoidance account of disgust by examining this same process for a nonpsychiatric illness: food poisoning. In addition, they introduce a composite measure of social distance behavior that is easy to implement in a laboratory experiment. The authors find, as predicted, that women seek greater social distance from teammates with a history of psychiatric or food poisoning hospitalization than they do from teammates with no hospitalization history. But, contrary to predictions, a teammate’s hospitalization history does not affect participants’ ratings of her likability. The results also do not vary significantly by psychiatric diagnosis (depression vs. schizophrenia), suggesting that the stigma of depression may be just as strong as the stigma of schizophrenia when information about symptoms is not available. The authors discuss the implications of these findings for the modified labeling theory of mental illness and for the literature on disgust and stigma. They also outline avenues for future research.
Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Somatic mutations of DNMT3A gene have recently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We examined the entire coding sequences of DNMT3A gene by high-resolution melting analysis and sequencing in Chinese patients with myeloid malignancies. R882 mutations were found in 12/182 AML and in 4/51 MDS, but not in either 79 chronic myeloid leukemia (CML), or 57 myeloproliferative neoplasms (MPNs), or 4 chronic monomyelocytic leukemia. No other DNMT3A mutations were detected in all patients. R882 mutations were associated with old age and more frequently present in monoblastic leukemia (M4 and M5, 7/52) compared to other subtypes (5/130). Furthermore, 14/16 (86.6%) R882 mutations were observed in patients with normal karyotypes. The overall survival of mutated MDS patients was shorter than those without mutation (median 9 and 25 months, respectively). We conclude that DNMT3A R882 mutations are recurrent molecular aberrations in AML and MDS, and may be an adverse prognostic event in MDS.
Association of Umbilical Venous With Inferior Vena Cava Blood Flow Velocities

The fetal cardiac and placental circulations are interconnected through the umbilical venous and arterial vasculature. We hypothesized that alterations in umbilical venous blood flow velocities are present in fetuses with abnormal umbilical arterial circulation, and further, that changes in inferior vena cava blood flow velocities occur with, and might explain, these variations in umbilical venous blood flow velocities. Umbilical venous and inferior vena cava blood flow velocities were examined in 15 normal fetuses and in 59 fetuses with abnormalities that included absent end-diastolic umbilical artery blood flow velocities (N=21) or abnormal heart rates (N=27). Inferior vena cava velocities were also analyzed in 11 other fetuses with anomalies or known growth or placental abnormalities who had abnormal umbilical venous blood flow velocities. In normal fetuses, variations in umbilical venous velocities occurred during fetal activity or with fetal breathing; however, no variation in velocity corresponded with heart rate. Eleven of 21 fetuses with absent end-diastolic velocities in the umbilical artery demonstrated decreases in umbilical venous velocities (“venous pulsations”) during arterial diastole. Blood flow velocities in the reverse direction, from the right atrium into the inferior vena cava with atrial contraction, were significantly greater in these fetuses than in those without umbilical venous pulsations (27.5 ± 14.9% and 7.5 ± 5.7% of total forward flow velocity, respectively;P<.001). Venous pulsations were also seen in fetuses with abnormally fast or slow heart rates; reverse flow with atrial contraction in the inferior vena cava was likewise greater than normal in these fetuses. We conclude that umbilical venous pulsations with heart rate are abnormal in human fetuses and that these pulsations are associated with and probably result from increases in inferior vena cava reverse flow velocity with atrial contraction, which signal alterations in cardiac function. Fetuses with umbilical venous pulsations should be examined carefully for further evidence of cardiovascular or circulatory abnormalities.
Aging Effects on Cobalt Availability in Soils

Aging processes in soils can significantly affect the potential biological availability of introduced metals via incorporation into crystal lattices, diffusion into micropores, or formation of metal precipitates on the surfaces of soil minerals. Over time, metals in contact with the soil solid phase are less freely exchangeable with the soil solution and, hence, less available to soil biota. In the present study, the effects of aging on the fate and behavior of added divalent cobalt (Co2+) in a range of soils with varying physicochemical characteristics was assessed using isotope‐exchange techniques, chemical extraction, and plant growth. Following addition to soil, the Co2+ salt rapidly partitioned to the soil solid phase. Particularly in soils with neutral to alkaline pH, a large percentage of the surface‐bound Co was fixed in forms no longer in equilibrium with soil solution cobalt through aging reactions. Using techniques commonly applied to estimate metal bioavailability in soil, the lability (E values), plant availability (L values), and extractability of added Co2+ salts with the mild chemical extractants calcium chloride (CaCl2) and ammonium nitrate (NH4NO3) were observed to markedly decrease with time, particularly in soils with high pH or those containing appreciable quantities of iron/ manganese oxyhydroxide minerals. Results indicated rapid partitioning of added Co2+ into isotopically nonexchangeable pools, with more than 60% of the aging occurring within 15 d in most soils. Soil pH was the primary factor controlling the rate of cobalt aging and extent of exchangeability in the soils examined. Understanding the influence of long‐term aging on cobalt availability in soils is necessary to accurately assess the potential risk associated with cobalt contamination of soil environments.
The ethics of pandering in Boston Public Schools’ school assignment plan

How can access to public elementary schools of variable quality be justly distributed within a school district? Two reasonable criteria are: (a) that children should have equal opportunity to attend high-quality schools, and (b) school assignment policies should foster an overall increase in the number of high-quality schools. This article analyzes Boston Public Schools’ new school assignment plan in light of these criteria. It shows that Boston Public Schools’ plan violates equal opportunity by giving middle-class families privileged access to existing high-quality schools. Boston Public Schools arguably panders to more-advantaged families, however, in order to pull them into the system and deploy their economic, political, and social capital to increase the total number of high-quality schools. Is this ethically defensible? To answer this question, we need to develop an ethical theory of pandering: of privileging the interests and preferences of already unjustly privileged actors because the consequences tend to benefit everyone. Such a theory will need to be ethically pluralistic and weighted along a contextually sensitive continuum, rather than rendered in all-or-nothing terms.
Preoccupied and Avoidant Coping during Middle Childhood

Prior research on attachment to caregivers during middle childhood has failed to include assessments of the divergent coping styles that insecure attachment can take. In this study, self-report scales were developed to assess children's preoccupied coping (strong need for mother during stress but inability to be soothed by her) and avoidant coping (denial of need for mother and avoidance of her during stress). The scales were administered to 229 boys and girls in the third through seventh grades (mean age 11.3 years) and were associated in theoretically meaningful ways with peers' reports of the children's adjustment at school. The advantage of including assessments of coping style in studies of attachment-adjustment relations in middle childhood is noted.