Miracle-dz/UniFAR-FTUs huggingface dataset:
Heritability of Subclinical Atherosclerosis in Latino Families Ascertained Through a Hypertensive Parent

Although clinical coronary heart disease and many cardiovascular risk factors are well known to aggregate within families, the heritability of carotid artery intima-media thickness (IMT) is less well documented. We report IMT heritability estimates in Mexican American, Salvadoran American, or Guatemalan American (all referred to as Latino) families ascertained through a hypertensive proband. IMT and cardiovascular risk factors (age, sex, blood pressure, body mass index, lipids, fasting glucose, and insulin sensitivity) were measured in 204 adult offspring of 69 hypertensive probands, along with 82 parents (54 probands and 28 spouses). In the offspring, variance component analysis revealed a heritability for IMT of 64% (P < 0.0001) after adjustment for significant cardiovascular risk factors. Genetic factors accounted for 50% of the total variation in IMT, whereas significant cardiovascular risk factors explained 22% (14% were due to age). For offspring and parents combined, adjusted IMT heritability was less, 34% (P =0.0005), with genetic factors accounting for 18% of the total IMT variation, whereas significant cardiovascular risk factors explained 46% (38% were due to age). We conclude that variation in c ommon carotid artery IMT is heritable in Latino families with a hypertensive proband. Heritability is particularly evident in younger family members, suggesting that acquired factors contribute progressively to IMT variability with aging.
Stress Reactivity, Social Anxiety, and Alcohol Consumption in People With Alcoholism: A Laboratory Study

Objective: Social anxiety may maintain alcohol dependence through increased reactivity to stressful events, a propensity to drink to cope with stressful events, or both. The current study is a secondary analysis of an existing data set that examined differences between individuals with alcohol dependence and concurrent high and low social anxiety in objective and subjective stress reactivity to a laboratory stressor (Trier Social Stress Test [TSST]), as well as consumption of alcohol following the stressor. Methods: Forty participants with alcohol dependence (20 women) were randomly assigned to the TSST condition as part of the parent study. Post hoc analysis of social anxiety measures yielded high (n = 19) and low (n = 21) social anxiety groups. Participants completed the TSST, followed by a small dose of their favorite alcoholic beverage (target blood alcohol concentration 0.03 g/dL) to prime subsequent laboratory drinking. Participants received a sham beer taste test of 2 glasses (710 mL total) of beer. Differences between high and low social anxiety groups were assessed via subjective and objective (mean arterial pressure, serum cortisol) reactivity to the TSST and consumption of alcohol during the taste test (total mLs consumed, mLs/kg of body weight, and likelihood of consuming all the beer available). Results: No differences emerged in either objective or subjective measures of stress reactivity between high and low social anxiety groups. There were also no differences between social anxiety groups in amount of alcohol consumed during the taste test. Conclusions: No differences were observed between high and low social anxiety participants with concurrent alcohol dependence on stress reactivity or alcohol consumption following a stressor. Given that all participants in this study had alcohol dependence, negative results may suggest that heightened stress reactivity and drinking to cope are more relevant to the development of alcohol dependence and that other factors may maintain alcohol use once dependence has developed.
A Discussion on Armington Trade Substitution Elasticities

Applied partial and general equilibrium models used to examine trade policy are almost universally sensitive to trade elasticities. Indeed, the Armington elasticity, the degree of substitution between domestic and imported goods, is a key behavioral parameter that drives the quantitative, and sometimes the qualitative, results that policymakers use. While standard transparent approaches to econometric estimation of these elasticities have been offered for the last 30 years, the estimates are viewed as too small by many trade economists. A few robust findings emerge from the econometric literature: (1) more disaggregate analyses find higher elasticities, (2) long-run estimates are higher than short-run estimates, and (3) time series analyses generally find lower elasticities relative to cross-sectional studies. We offer simulation results to illustrate the sensitivity of general equilibrium models to Armington elasticites. We conclude with remarks on the current challenges that remain in determining these important parameters.
The Multilinear Structure of ReLU Networks

We study the loss surface of neural networks equipped with a hinge loss criterion and ReLU or leaky ReLU nonlinearities. Any such network defines a piecewise multilinear form in parameter space. By appealing to harmonic analysis we show that all local minima of such network are non-differentiable, except for those minima that occur in a region of parameter space where the loss surface is perfectly flat. Non-differentiable minima are therefore not technicalities or pathologies; they are heart of the problem when investigating the loss of ReLU networks. As a consequence, we must employ techniques from nonsmooth analysis to study these loss surfaces. We show how to apply these techniques in some illustrative cases.
The Role of Human Resource Development in Preventing Organisational Stagnation

The purpose of this paper is to argue that how HRD is undertaken needs careful consideration, since some HRD implementation schemes may actually prevent the acquisition of new knowledge, thereby developing stagnation. The paper uses qualitative data derived from learning and non-learning organisations. The data were collected from four companies via open-ended questionnaires and structured interviews. The paper demonstrates how strongly shared mental models may affect organisational HRD processes in such a way as to trigger closure to new knowledge and learning. The types of learning and knowledge present in the organisations are found to limit the possibility of radical change.HRD implementation systems themselves may strengthen mental models, thereby allowing the difficulties to emerge because the learning and knowledge being developed will only support incremental change if any. The potential reversion of the direction of organisational learning is mooted, indicating that new ideas may either not enter the system or be rejected once they are perceived. HRD systems need to be designed to develop and maintain organisational openness. The danger of HRD exacerbating organisational closure is explained. An alternative role for HRD professionals is outlined, with the new focus being on developing ongoing challenge at all times. The paper concludes that, although properly structured and thoughtfully implemented HRD can be a positive driver for organisational learning, HRD developments need to focus on the type of knowledge being developed as well as the level of learning.
Star-Analysts’ Forecast Accuracy and the Role of Corporate Governance

type="main" xml:lang="en"> In this article we examine whether star-analysts have better forecasting abilities than non-star-analysts. Our results reveal that star-analysts' earnings forecasts outperform their peers' forecasts. Because the level of corporate governance plays an important role for the general level of forecast accuracy, we furthermore investigate whether star-analysts benefit from higher levels of governance. Our findings suggest that forecast accuracy of star-analysts increases with the level of both country- and company-specific corporate governance. Investors in capital markets do not seem to be aware of this fact because they do not react differently to forecasts issued by star-analysts compared to those of non-star-analysts.
Ameloblastic carcinoma: a Brazilian collaborative study of 17 cases

Ameloblastic carcinoma (AMECA) is an odontogenic malignancy that combines the histological features of ameloblastoma and cytological atypia. Because of its rarity, it poses difficulties in diagnosis. The aim of this study was to investigate the socio‐demographic data, histopathology, immunohistochemical features, treatment and outcomes of 17 cases.
Determinants of Income Inequality in Botswana

This paper utilizes regression based inequality decomposition methodology developed by Field (2003) to determine factors driving income inequality at household level in Botswana. Using the Household Income and Expenditure Survey of 2002/03 an income generating function is estimated using OLS. This provides an efficient and flexible way to quantify the roles of household variables like education and age on inequality in a multivariate context. Results of the inequality decomposition indicate that secondary school education, training, Value Added Tax, number of children and number of working adults in the household contribute significantly to inequality in Botswana. On the other hand, variables like primary education, age and owning between 1 and 10 head of livestock equalises income inequality.
Isolation of the left subclavian artery from the pulmonary artery in a patient with CHARGE association

A male infant diagnosed with CHARGE association presented with respiratory insufficiency and a cardiac murmur. Diagnostic evaluation showed a right sided aortic arch with an isolation of the left subclavian artery arising from the pulmonary artery through a left patent arterial duct. This is a rare cardiac disorder not previously described in patients with CHARGE association, detected with a 3D computed tomography scan, which emphasizes the importance of a thorough cardiac screening in patients with CHARGE association.
External Information Search Behavior of Visitors to Turkey

ABSTRACT The purpose of this study is to analyze the influence of information search behavior of travelers from 36 countries to Turkey. The data used in this study were obtained from a larger research project which was carried out by Ministry of Tourism and Culture and State Statistics Association of Turkey in 2001. The study revealed seven dimensions of external information sources as a part of search behavior of visitors such as “friends and relatives,” “trade exhibition,” “promotion offices,” “media,” “tourism entities,” “others” (Internet, catalog and in-flight information) and “outside of the above sources. ” The data were analyzed by two different techniques. First, a series of Chi-square tests were conducted to examine the information sources of visitors arriving in Turkey. Second, Correspondence Analysis (CA) was utilized to identify the differences in the information sources of visitors. Six external information sources were examined in the study.
A Portrait of Prisoner Reentry in Texas

The number of people released from Texas prisons and state jails in 2001 was over five times the number released two decades ago. One-quarter of those released in 2001 returned to Harris County, and many were even more concentrated within a few distressed neighborhoods. This report describes the process of prisoner reentry in Texas by examining the policy context surrounding reentry, the characteristics of Texas's returning prisoners, their geographic distribution after release, and the social and economic climates of the communities that are home to the highest concentrations of returning prisoners. [View the corresponding press release ]
Very Long-chain Polyunsaturated Fatty Acids Are the Major Acyl Groups of Sphingomyelins and Ceramides in the Head of Mammalian Spermatozoa*

Very long-chain (C24 to C34) polyunsaturated fatty acids (VLCPUFA) are important constituents of sphingomyelin (SM) and ceramide (Cer) in testicular germ cells. In the present paper we focused on the SM and Cer and their fatty acids in spermatozoa and their main regions, heads and tails. In bull and ram spermatozoa, SM was the third most abundant phospholipid and VLCPUFA were the major acyl groups (∼70%) of SM and Cer. In rat epididymal spermatozoa the SM/Cer ratio was low in the absence of and could be maintained high in the presence of the cation chelator EDTA, added to the medium used for sperm isolation. This fact points to the occurrence of an active divalent cation-dependent sphingomyelinase. Bull and rat sperm had an uneven head-tail distribution of phospholipid, with virtually all the VLCPUFA-rich SM located at the head, the lower SM content in the rat being determined by the lower sperm head/tail size ratio. Most of the SM from bull sperm heads was readily solubilized with 1% Triton X-100 at 4 °C. The detergent-soluble SM fraction was richer in VLCPUFA than the nonsoluble fraction and richer in saturated fatty acids. Cer was produced at the expense of SM, thus decreasing severalfold the SM/Cer ratio in rat spermatozoa incubated for 2 h in presence of the sperm-capacitating agents, calcium, bicarbonate, and albumin. The generation of Cer from SM in the sperm head surface may be an early step among the biochemical and biophysical changes known to take place in the spermatozoon in the physiological events preceding fertilization.
Return distributions and volatility forecasting in metal futures markets: Evidence from gold, silver, and copper

The characterization of return distributions and forecast of asset‐price variability play a critical role in the study of financial markets. This study estimates four measures of integrated volatility—daily absolute returns, realized volatility, realized bipower volatility, and integrated volatility via Fourier transformation (IVFT)—for gold, silver, and copper by using high‐frequency data for the period 1999 through 2008. The distributional properties are investigated by applying recently developed jump detection procedures and by constructing financial‐time return series. The predictive ability of a GARCH (1,1) forecasting model that uses various volatility measures is also examined. Three important findings are reported. First, the magnitude of the IVFT volatility estimate is the greatest among the four volatility measures. Second, the return distributions of the three markets are not normal. However, when returns are standardized by IVFT and realized volatility, the corresponding return distributions bear closer resemblance to a normal distribution. Notably, the application of financial‐time sampling technique is helpful in obtaining a normal distribution. Finally, the IVFT and realized volatility proxies produce the smallest forecasting errors, and increasing the time frequency of estimating integrated volatility does not necessarily improve forecast accuracy. © 2010 Wiley Periodicals, Inc. Jrl Fut Mark 31:55–80, 2011
Hospital Costs for Stroke Care in Singapore

We performed this prospective study to determine the cost of care for acute stroke patients admitted to hospital. Stroke was subtyped into subarachnoid hemorrhage (SAH), intraparenchymal hemorrhage (IPH), nonlacunar infarct (NLC), lacunar infarct (LAC) and transient ischemic attack (TIA). Cost of care was computed for the various services the patient received. At the time of the study, US$ 1 = S$1.50. 426 patients were studied. Mean length of stay (LOS) was 17 days. Mean cost/discharge was S$7,547. Ward charges accounted for 38.2%, radiology 14.5%, doctors’ fees 10.3%, drugs 8.4%, therapy 7.3%. Cost was highly correlated with LOS, r2 = 0.73. Mean cost/discharge was SAH S$28,539, IPH S$14,398, NLC S$7,476, LAC S$3,517, TIA S$1,962. Initial hospitalization cost for stroke is highly correlated with LOS. The bulk of cost is attributable to ward stay. Cost/discharge is highest with SAH, and in descending order IPH, NLC, LAC, TIA.
Retesting the Uncertainty Effect Using Lotteries with Real Products and Money

In the current study, several experiments re‐examine the uncertainty effect using lotteries that include real products, monetary outcomes and electronic gift cards in a between‐subjects design. The study also takes the selling position into consideration, in addition to the buying position considered by all previous works on the uncertainty effect. The results indicate that for all types of lotteries, the bids are higher than the bids for the worst possible realization. These findings are consistent with the internality axiom and do not support the uncertainty effect.
Monetary policy transmission in the CEECs : a comprehensive analysis

This paper aims at providing better supported results regarding monetary policy transmission in Central and Eastern European countries (CEECs). In the general frame of VAR models, our study differs from previous research in two main respects. Firstly, we provide estimations which do not rely on the hypothesis of cointegration usually exploited in the related literature, but economically meaningless over less than ten years spans and statistically very fragile. Secondly, we present another set of results, relying on real GDP monthly data that have been rebuilt using the Chow and Lin (1971) method ; this allows for an alternative to the traditional industrial production data, a partial and highly unstable proxy variable for output. These original methodological insights lead to results emphasizing the general prevalence of exchange rate and domestic credit channels for monetary policy transmission across the studied countries, despite some persistent national specificities. The empirical evidence also incites to be reasonably optimistic regarding the relevancy of a close integration of these countries into euro area.
Drug compliance among hypertensive patients in Port Harcourt, Nigeria.

BACKGROUND Hypertension contributes significantly to cardiovascular morbidity and mortality. Adequate blood pressure control would therefore reduce cardiovascular morbidity and mortality, however adequate blood pressure control requires good treatment compliance. METHODS One hundred consecutive patients aged 30-79 years attending the cardiac clinic of the medical out-patients clinic of the University of Port Harcourt Teaching Hospital were directly questioned about compliance with their antihypertensive drugs and results entered into the questionnaire designed for the study. RESULTS Compliance was good in sixty percent (60%) of respondents, fair in twenty nine percent (29%) and poor in eleven percent (11%). Compliance was also found to be good in sixty-seven percent (67%) of patients with tertiary education, good in forty one percent (41%) of those with primary education. Compliance was good in seventy four percent (74%) of those taking one drug, good in only thirty three percent (33%) of those taking four drugs. Patients taking single daily dose drugs had good compliance in seventy percent (70%), twice daily dosing had good compliance in fifty five percent (55%) and among those taking thrice daily dosage, compliance was good in only seventeen percent (17%). CONCLUSION The study shows that good compliance with anti-hypertensive therapy is best achieved with monotherapy given as single dosage. It also shows the role of education in the level of compliance.
Associations between workers' health, and non-standard hours and insecurity: the case of home care workers in Ontario, Canada

This article examines associations between home care workers' health, and non-standard hours and insecurity. Health refers to symptoms of stress and musculoskeletal disorders (MSDs), non-standard hours refer to part-time and casual hours, and insecurity refers to job and employability insecurity. Data come from our 2002 survey of 532 home care workers (nurses, therapists and personal support workers) in a medium-sized city in Ontario, Canada. Path analysis regression results for the conceptual model show that (1) part-time and casual hours and job insecurity are positively and significantly associated with symptoms of stress, (2) the associations between part-time and casual hours and MSDs are mediated by symptoms of stress, and (3) job and employability insecurity are directly associated with MSDs. Results provide evidence that non-standard hours and insecurity must be addressed in order to improve home care workers' health. We show the detrimental effects of non-standard hours and insecurity on workers' health, and the results have implications for employers, human resource managers, trade unionists and government policy-makers.
Financing Higher Education in Tunisia

This paper focuses on Tunisia, which like other developing countries, has allocated increasing levels of resources to education, particularly higher education, mainly through public funding over the past few decades. In 2005-2008, public expenditure on education amounted to around 7.4 percent of GDP, with 2 percent allocated to higher education. However, in the last few years, the budgetary constraints have increased, and are likely to remain so in the near future. These budgetary constraints exist within a context of rapidly increasing student enrollment, and the need to improve the quality of education to insure better employability of graduates. In light of this situation, public policy is obliged to define orientations and programs, improving quality and efficiency while reducing costs and resource wastage, to enhance access and equity. This paper is organized as follows: it begins with an assessment of public expenditure on higher education in Tunisia, with respect to its adequacy, efficiency and equity. Next, in section 2, we explore the challenges posed to financing by demographic evolution, the quality of education and private provision. Section 3 examines some financing reinforcement strategies, and analyzes feasible measures to raise private funding contributions. Section 4 provides some concluding remarks.
Cancer incidence among Icelandic deck officers in a population-based study.

OBJECTIVES The aim of this study was to define the cancer pattern in an Icelandic cohort of deck officers while indirectly controlling for their smoking habits. METHODS A cohort of 3874 male deck officers was followed from 1966 to 1998. It was record-linked by the deck officers' personal identification numbers to population-based registers containing each person's vital and emigration status and cancer diagnosis. Standardized incidence ratios (SIR) were calculated for all cancers and different cancer sites in relation to different lag times and years of birth. Information on smoking habits was obtained by from a questionnaire administered to a sample of the cohort (N=728). RESULTS In the total cohort 436 cancers were observed, equal to the expected 436 [SIR 1.0, 95% confidence interval (95% CI) 0.9-1.1], and a significantly increased risk of soft-tissue sarcoma (SIR 2.7, 95% CI 1.2-5.1) was found together with a decreased risk of testis cancer (SIR 0.0, 95% CI . -0.7) and urinary bladder cancer (SIR 0.5, 95% CI 0.3-0.8). The deck officers' smoking habits were similar to those found in a sample of the general population. The predictive value was 1.11 for lung cancer CONCLUSIONS An increased incidence of soft-tissue sarcoma was found among deck officers. This increase resembles that previously found for Swedish deck officers, and it warrants further study.