Miracle-dz/UniFAR-FTUs huggingface dataset:
Personal agency in children

The aim of this study is to develop a multidimensional measure for assessing children’s personal agency to handle parental conflict through their coping self-efficacy beliefs (Bandura, 1997). Coping self-efficacy beliefs are individuals’ perceived ability to motivate themselves, access cognitive resources, and perform the actions required to take control of stressful situations. This study examines the psychometric properties and validation of the newly created Parental Conflict Coping Self-Efficacy Scale (PCC-SES). The study was based on 663 children, in grades 5 and 7 and their mothers. An exploratory factor analysis and confirmatory factor analysis through structural equation modeling supported the structure of the PCC-SES. The PCC-SES’s structure was facilitated by three global strategies, namely Proactive Behavior (problem solving and seeking social support), Avoiding Maladaptive Cognitions (avoiding preoccupation, avoiding self-blame and distancing) and Avoiding Maladaptive Behavior (avoiding aggression and avoiding overinvolvement).
Analysis and Optimization of Convolutional Neural Network Architectures

Convolutional Neural Networks (CNNs) dominate various computer vision tasks since Alex Krizhevsky showed that they can be trained effectively and reduced the top-5 error from 26.2 % to 15.3 % on the ImageNet large scale visual recognition challenge. Many aspects of CNNs are examined in various publications, but literature about the analysis and construction of neural network architectures is rare. This work is one step to close this gap. A comprehensive overview over existing techniques for CNN analysis and topology construction is provided. A novel way to visualize classification errors with confusion matrices was developed. Based on this method, hierarchical classifiers are described and evaluated. Additionally, some results are confirmed and quantified for CIFAR-100. For example, the positive impact of smaller batch sizes, averaging ensembles, data augmentation and test-time transformations on the accuracy. Other results, such as the positive impact of learned color transformation on the test accuracy could not be confirmed. A model which has only one million learned parameters for an input size of 32x32x3 and 100 classes and which beats the state of the art on the benchmark dataset Asirra, GTSRB, HASYv2 and STL-10 was developed.
Molecular Epidemiology and Clinical Impact of Acinetobacter calcoaceticus-baumannii Complex in a Belgian Burn Wound Center

Multidrug resistant Acinetobacter baumannii and its closely related species A. pittii and A. nosocomialis, all members of the Acinetobacter calcoaceticus-baumannii (Acb) complex, are a major cause of hospital acquired infection. In the burn wound center of the Queen Astrid military hospital in Brussels, 48 patients were colonized or infected with Acb complex over a 52-month period. We report the molecular epidemiology of these organisms, their clinical impact and infection control measures taken. A representative set of 157 Acb complex isolates was analyzed using repetitive sequence-based PCR (rep-PCR) (DiversiLab) and a multiplex PCR targeting OXA-51-like and OXA-23-like genes. We identified 31 rep-PCR genotypes (strains). Representatives of each rep-type were identified to species by rpoB sequence analysis: 13 types to A. baumannii, 10 to A. pittii, and 3 to A. nosocomialis. It was assumed that isolates that belonged to the same rep-type also belonged to the same species. Thus, 83.4% of all isolates were identified to A. baumannii, 9.6% to A. pittii and 4.5% to A. nosocomialis. We observed 12 extensively drug resistant Acb strains (10 A. baumannii and 2 A. nosocomialis), all carbapenem-non-susceptible/colistin-susceptible and imported into the burn wound center through patients injured in North Africa. The two most prevalent rep-types 12 and 13 harbored an OXA-23-like gene. Multilocus sequence typing allocated them to clonal complex 1 corresponding to EU (international) clone I. Both strains caused consecutive outbreaks, interspersed with periods of apparent eradication. Patients infected with carbapenem resistant A. baumannii were successfully treated with colistin/rifampicin. Extensive infection control measures were required to eradicate the organisms. Acinetobacter infection and colonization was not associated with increased attributable mortality.
Delayed intestinal absorption of levothyroxine.

We report four female patients with nodular goiter (in two of the four due to Hashimoto's thyroiditis) and one male patient with frank hypothyroidism due to Hashimoto's thyroiditis in whom TSH-suppressive or replacement L-T4 therapy failed to suppress or, respectively, normalize serum TSH. As is typical in our country, our patients took L-T4 15-20 min before a light breakfast. Gastrointestinal or other diseases and drugs known to interfere with the intestinal absorption of L-T4 were not the cause of this failure. The gastrointestinal absorption test of L-T4 (1000 micrograms) was performed in four patients; in three patients it revealed peculiar abnormalities in that (i) the absorption peak was > 70% but occurred at 4 hr vs an average of 2 hr in 12 euthyroid controls (EC) and 3 hr in the 10 primary hypothyroid controls (HC); (ii) 50% of the maximal absorption occurred at 110 min vs 45 min in EC and 50 min in HC; (iii) the maximal increment in T4 absorption was between 90 and 120 min (+111%) vs between 30 and 60 min in EC (+312%) and HC (+354%). In sum, only the first part of the absorption curve of T4 was shifted to the right (in three of the four women) and this shift was more pronounced and extended to the second part of the curve in the fourth patient; in this last patient absorption peak was 44% at 180 min. Based on these results, we obtained full suppression or normalization of TSH by postponing breakfast for at least 60 min after T4 ingestion. (ABSTRACT TRUNCATED AT 250 WORDS)
A GIOVE Derived Galileo Electron Spectrum and Comparison to Models

Two precursor satellites for the European satellite navigation system, Galileo have been launched, GIOVE-A and -B. Both spacecraft carry monitors to characterise the radiation environment in the MEO environment. CEDEX, built by the University of Surrey and Merlin, built by QinetiQ, are carried on GIOVE-A and SREM built by Oerlikon Space is on board GIOVE-B. All three monitors have been operating since their respective launches and have measured the trapped electron population as well as solar protons and GCRs. An electron energy spectrum has been derived from Merlin measurements and validated with data from GIOVE-B/SREM and the IREM instrument on the INTEGRAL observatory. The derived energy spectra are compared to environment models, suggesting a harder energy spectrum than expected, but not exceeding worst-case FLUMIC predictions.
Prenatal diagnosis of isovaleric acidaemia by enzyme and metabolite assay in the first and second trimesters

Isovaleric acidaemia (IVA) is caused by a deficiency of isovaleryl CoA dehydrogenase. The diagnosis can be established biochemically by the demonstration of increased levels of isovalerylglycine (IVG) and 3‐hydroxyisovaleric acid in urine and by the deficiency of incorporation of radiolabel from [14C]isovaleric acid in macromolecules in cultured fibroblasts. This paper reports a consecutive series of 24 prenatal diagnoses in pregnancies at high risk, using both methods‐metabolite and indirect enzyme assay. Affected fetuses were diagnosed in four pregnancies: three in the second trimester and one recent case in the first trimester. The latter represents the first reported case of a first‐trimester diagnosis of IVA by direct analysis of chorionic villi. We also report the first demonstration of strongly accumulated IVG in the amniotic fluid in the 12th week of an affected pregnancy.
Culture as a Moderator in High Commitment Management: Affective Commitment Link

Affective organizational and occupational commitment is crucial for organizations. It has been proven that usage of High Commitment Management (HCM) practices improves affective organizational commitment, but no attention was paid to its influence on occupational type of commitment. They also measured direct influence of national culture on both construct; however, their findings often did not support with each other. By conducting a comparative research among university employees in the Netherlands and Poland HCM was proven to positively influence affective organizational and occupational commitment. Obtaining mixed results from moderated linear regression (only one cultural dimension had actual impact on the correlation between HCM and a focus of commitment) led to leaving the issue of influence of national culture on this correlation. Yet, there are perquisites that led to conclusion that confirmatory studies need to be done in the future to support these findings.
Expressed attachment to Russia and social integration: the case of young Russian speakers in Latvia, 2004–2010

ABSTRACT The aim of this article is to establish if expressed attachment to Russia, amongst surveyed Russian-speaking youths in 2004 and 2010 in Latvia, demonstrates any noteworthy correlations with factors promoting integration and feelings of belonging to Latvia. The correlation analysis shows that a sense of belonging to Russia and a sense of belonging to Latvia are not mutually exclusive. However, those Russian speakers in Latvia expressing a closer sense of belonging to Russia are also more likely to prefer an all-Russian environment, are skeptical of their rights and influence in Latvia, and are more likely to perceive discrimination in terms of citizenship status and ethnicity. These preferences suggest either a lack of integration or an “external homeland” influence.
Female Patients Undergoing TEVAR May Have an Increased Risk of Postoperative Spinal Cord Ischemia

Background: There is a paucity of literature regarding thoracic endovascular aneurysm repair (TEVAR) in women. We report our institutional experience with TEVAR. Methods: Retrospective chart review was performed from 2004 to 2008. TEVAR was performed in 59 patients; 29 (49%) were female. Results: Mean age was 73.5 years. Mean thoracic aortic aneurysm (TAA) diameter was larger for women (5.9 cm vs 4.7 cm). A trend toward an increase in paraplegia was noted in women, 10.3% vs 4.8%. This may be related to increase in length of aortic coverage in women, 18.2 cm vs 15.2 cm (P < .05). Conclusion: TEVAR in women is safe and effective. The length of aortic coverage is greater in women, which may be related to larger aneurysms and more diffuse disease. This may be associated with a concerning increase in postoperative paraplegia. Women undergoing TEVAR should be considered for prophylactic maneuvers to prevent spinal cord ischemia (SCI), including minimizing length of coverage.
Get around 360° hypervideo

In traditional video, the user is locked to the angle where the camera was pointing to during the capture of the video. With 360° video recording, there are no longer these boundaries, and 360° video capturing devices are becoming more common and affordable to the general public. Hypervideo stretches boundaries even further, allowing to explore the video and to navigate to related information. In this paper, we describe an approach to the design and development of an immersive and interactive interface for the visualization and navigation of 360° hypervideos over the internet. Such videos allow users to pan around to view the contents in different angles and effectively access related information through the hyperlinks. Challenges for presenting this type of hypervideo include: providing users with an appropriate interface capable to explore 360° contents, where the video should change perspective so that the users actually get the feeling of looking around; and providing the appropriate affordances to understand the hypervideo structure and to navigate it effectively in a 360° hypervideo space, even when link opportunities arise in places outside the current viewport.
Synaptic dynamics control the timing of neuronal excitation in the activated neocortical microcircuit

It is well established that sensory stimulation results in the activity of multiple functional columns in the neocortex. The manner in which neurones within each column are active in relation to each other is, however, not known. Multiple whole‐cell recordings in activated neocortical slices from rat revealed diverse correlation profiles of excitatory synaptic input to different types of neurones. The specific correlation profile between any two neurones could be predicted by the settings of synaptic depression and facilitation at the input synapses. Simulations further showed that patterned activity is essential for synaptic dynamics to impose the temporal dispersion of excitatory input. We propose that synaptic dynamics choreograph neuronal activity within the neocortical microcircuit in a context‐dependent manner.
Blockade of CD40–CD154 Costimulatory Pathway Promotes Long‐Term Survival of Full‐Thickness Porcine Corneal Grafts in Nonhuman Primates: Clinically Applicable Xenocorneal Transplantation

The porcine cornea may be a good solution for the shortage of human donor corneas because its size and refractive properties are comparable to those of the human cornea. However, antigenic differences need to be overcome to apply xenocorneal transplantation in actual clinical practice. We aimed to investigate the feasibility of full‐thickness porcine corneas as human corneal substitutes using a CD40–CD154 costimulatory pathway blocking strategy in a clinically applicable pig‐to‐nonhuman primate corneal transplantation model. As a result, the mean survival time of the xenocorneal grafts in recipients who received anti‐CD154 antibody‐based immunosuppressants (POD318 (n = 4); >933, >243, 318 and >192) was significantly longer than that in controls (POD28 (n = 3); 21, 28 and 29; p = 0.010, log‐rank test). Administration of anti‐CD154 antibodies markedly reduced inflammatory cellular infiltrations (predominantly CD8 T cells and macrophages) into the xenocorneal grafts and almost completely blocked xenoantigen‐triggered increases in Th1‐associated cytokines, chemokines and C3a in the aqueous humor. Moreover, systemic expansion of memory T cells was effectively controlled and responses of anti‐Gal/donor pig‐specific antibodies were considerably diminished by programmed injection of anti‐CD154 antibodies. Consequently, porcine corneas might be promising human corneal substitutes when the transplantation is accompanied by potent immunosuppression such as a CD40–CD154 costimulatory pathway blockade.
MOSIX Evaluation on a Linux Cluster

Multicomputer Operating System for Unix (MOSIX) is a cluster-computing enhancement of Linux kernel that supports preemptive process migration. It consists of adaptive resource sharing algorithms for high performance scalability by migrating processes across a cluster. Message passing Interface (MPI) is a library standard for writing message passing programs, which has the advantage of portability and ease of use. This paper highlights the advantages of a process migration model to utilize computing resources better and gain considerable speedups in the execution of parallel and multi-tasking applications. We executed several CPU bound tests under MPI and MOSIX. The results of these tests show the advantage of using MOSIX over MPI. At the end of this paper, we present the performance of the executions of those tests, which showed that in some cases improvement in the performance of MOSIX over MPI can reach tens of percents.
KEPLER ECLIPSING BINARY STARS. I. CATALOG AND PRINCIPAL CHARACTERIZATION OF 1879 ECLIPSING BINARIES IN THE FIRST DATA RELEASE

The Kepler space mission is devoted to finding Earth-size planets orbiting other stars in their habitable zones. Its large, 105 deg2 field of view features over 156,000 stars that are observed continuously to detect and characterize planet transits. Yet, this high-precision instrument holds great promise for other types of objects as well. Here we present a comprehensive catalog of eclipsing binary stars observed by Kepler in the first 44 days of operation, the data being publicly available through MAST as of 2010 June 15. The catalog contains 1879 unique objects. For each object, we provide its Kepler ID (KID), ephemeris (BJD0, P0), morphology type, physical parameters (Teff, log g, E(B − V)), the estimate of third light contamination (crowding), and principal parameters (T2/T1, q, fillout factor, and sin i for overcontacts, and T2/T1, (R1 + R2)/a, esin ω, ecos ω, and sin i for detached binaries). We present statistics based on the determined periods and measure the average occurrence rate of eclipsing binaries to be ∼1.2% across the Kepler field. We further discuss the distribution of binaries as a function of galactic latitude and thoroughly explain the application of artificial intelligence to obtain principal parameters in a matter of seconds for the whole sample. The catalog was envisioned to serve as a bridge between the now public Kepler data and the scientific community interested in eclipsing binary stars.
Kernel Regression with Order Preferences

We propose a novel kernel regression algorithm which takes into account order preferences on unlabeled data. Such preferences have the form that point x1 has a larger target value than that of x2, although the target values for x1, x2 are unknown. The order preferences can be viewed as side information or a form of weak labels, and our algorithm can be related to semi-supervised learning. Learning consists of formulating the order preferences as additional regularization in a risk minimization framework. We define a linear program to effectively solve the optimization problem. Experiments on benchmark datasets, sentiment analysis, and housing price problems show that the proposed algorithm outperforms standard regression, even when the order preferences are noisy.
Sensitivity of Sclerotinia Homoeocarpa to Demethylation- Inhibiting Fungicides in Ontario, Canada, after a Decade of Use

In late 2003, nine populations of Sclerotinia homoeocarpa in Ontario Canada (seven of which had been previously sampled in early 1994, prior to the registration of sterol demethylation-inhibiting (DMI) fungicides for turf disease control in Canada) were sampled and tested for sensitivity to propiconazole. Four of the nine populations had not been treated with DMI fungicides during the intervening years, and isolates from these locations were sensitive to propiconazole (geometric mean EC 50 values of 0·005–0·012 µ g mL − 1 , compared with 0·005–0·008 µ g mL − 1 for the original 1994 populations). Among the five populations from 2003 that had been exposed to DMI fungicides, mean EC 50 values were significantly greater, ranging from 0·020 to 0·048 µ g mL − 1. A significant correlation of determination was found between estimated number of fungicide applications and log EC 50 (R 2 = 0·832, P = 0·0001), and the equation predicted that 42·3 applications of propiconazole would be needed to bring a sensitive population (EC 50 < 0·01 µ g mL − 1) to a resistant level (EC 50 > 0·10 µ g mL − 1). Fungicide sensitivity vs. duration of fungicide efficacy was also tested, and it was found that isolates with decreased sensitivity were able to more quickly overcome the inhibitory effects of fungicide application, reducing the duration of control from 3 weeks to 2 weeks.
Therapeutic drug monitoring of infliximab: performance evaluation of three commercial ELISA kits

Abstract Background: Therapeutic drug monitoring (TDM) of infliximab (IFX, Remicade®) can aid to optimize therapy efficacy. Many assays are available for this purpose. However, a reference standard is lacking. Therefore, we evaluated the analytical performance, agreement and clinically relevant differences of three commercially available IFX ELISA kits on an automated processing system. Methods: The kits of Theradiag (Lisa Tracker Infliximab), Progenika (Promonitor IFX) and apDia (Infliximab ELISA) were implemented on an automated processing system. Imprecision was determined by triplicate measurements of patient samples on five days. Agreement was evaluated by analysis of 30 patient samples and four spiked samples by the selected ELISA kits and the in-house IFX ELISA of Sanquin Diagnostics (Amsterdam, The Netherlands). Therapeutic consequences were evaluated by dividing patients into four treatment groups using cut-off levels of 1, 3 and 7 μg/mL and determining assay concordance. Results: Within-run and between-run imprecision were acceptable (≤12% and ≤17%, respectively) within the quantification range of the selected ELISA kits. The apDia assay had the best precision and agreement to target values. Statistically significant differences were found between all assays except between Sanquin Diagnostics and the Lisa Tracker assay. The Promonitor assay measured the lowest IFX concentrations, the apDia assay the highest. When patients were classified in four treatment categories, 70% concordance was achieved. Conclusions: Although all assays are suitable for TDM, significant differences were observed in both imprecision and agreement. Therapeutic consequences were acceptable when patients were divided in treatment categories, but this could be improved by assay standardization.
Multi-class AUC metrics and weighted alternatives

The area under the receiver operating characteristic curve (AUC) is a useful and widely used measure to evaluate the performance of binary and multi-class classification models. However, it does not take into account the exact numerical output of the models, but rather looks at how the output ranks the cases. AUC metrics that incorporate the exact numerical output have been developed for binary classification. In this paper, we try to extend such weighted metrics to the multi-class case. Several metrics are suggested. Using real world data, we investigate intercorrelations between these metrics and demonstrate their use.
Load Dependency of Postural Control - Kinematic and Neuromuscular Changes in Response to over and under Load Conditions

Introduction Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL) and under loading (UL) used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms. Methods Balance performance was recorded under normal loading (NL, 1g), UL (0.16g; 0.38g) and OL (1.8g) in monopedal stance. Center of pressure (COP) displacement and frequency distribution (low 0.15-0.5Hz (LF), medium 0.5-2Hz (MF), high 2-6Hz (HF)) as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios). Results Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL. Conclusion Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal segments to adjust the center of gravity above the base of support.