Miracle-dz/UniFAR-FTUs huggingface dataset:
Ansiedad estado competitiva y estrategias de afrontamiento : su relación con el rendimiento en una muestra argentina de jugadores amateurs de golf

The aim of the study is to analyse whether there exists a relationship between the level of competitive state anxiety, the use of coping strategies and the performance of a sample of 77 Argentinian amateur golf players (mean age: 16.14). The design of the study was descriptive, correlational and transversal. For data collection the Spanish versions of the Competitive State Anxiety Inventory and the Approach to Coping in Sport Questionnaire were administered. While golf players who show a poorer handicap reveal higher levels of somatic anxiety (r = .30; p < .01), those who achieve better performance in tournaments are the ones who have higher levels of self-confidence (r = -.31; p < .01) and resort to social support as a coping strategy (r = -.27; p < .01).
Personal air and car travel - just don't do it!

Greenhouse gas emissions from personal transport have risen steadily in the UK and most other countries of the EU. Yet surprisingly little is known about who exactly is contributing to the problem at the personal level and the extent to which diff erent groups of the population will be aff ected by the any responses to the climate change problem. Th is paper describes an innovative methodology and evaluation tool for profi ling annual climate change emissions from personal travel across all modes of travel. A case study application of the methodology involving surveys of UK residents provides an improved understanding of the extent to which individual and household travel activity patterns, choice of transport mode, geographical location, socio-economic factors and vehicle technology choice impact on greenhouse gas emissions. Air travel dominates overall emissions, particularly when including climate eff ects of non-CO 2 greenhouse gas emissions. Conversely, land based public transport accounts for a very small proportion of emissions on average. Th ere is a highly unequal distribution of emissions amongst the population, independent of the mode of travel, location and unit of analysis (individual/household). In particular, there are large disparities between individuals/ households: some 20 % of the respondents drove but did not fl y although the same number fl ew but did not drive. Th e top 10 % of emitters are responsible for 43 % of emissions and the bottom 10 % for only 1 %, with those in the top 10 % fl ying 5 times more than the sample average. Th e area analysis (urban vs. rural) shows higher levels of urban emissions due to higher propensity to travel by air. Air travel emissions of fl yers and non-fl yers are also signifi cantly infl uenced by income levels. Key policy implications of the results are discussed. Th e paper concludes by suggesting potential applications of the methodology and evaluation tool.
Scattering Investigation of Acoustic Localization in Fused Silica.

Small angle neutron time-of-flight spectroscopy and inelastic x-ray scattering results are reported on the acoustic vibrations of fused silica. An expression for the dynamical structure factor is given that successfully describes the scattering from these vibrations, including the boson peak. The data analysis indicates an acoustic localization edge at > 1 THz, in agreement with the position of the thermal conductivity plateau. Scattering results on another strong glass support the generality of our description. [S0031-9007(96)01538-4]
An Approach to Identify Failure Factors of Enterprise Application Implementation in Indian Micro Enterprises

Enterprise Business Application or in other words ERP can be regarded as a novel business solution. Today organizations of any magnitude areimplementing and some are in the process of implementing such Enterprise Information System. Implementation of EnterpriseBusiness Application is quite difficult and complex process and has been subjected to substantial research. As cases of ERP failures have increased many researches have been carried out to identify which issues can lead to implementation successful. It has been observed while compiling the literature thatmajority of the previous studies and research projects have been conducted in identifying the critical success factorsrather than critical failure factors. From the literature it has been observed that most of the developed countries had been reaping the benefits of enterprise application integration since long time and because of itsadvantages now a day developing countries too are embracing such technology integration.Developing countries which mostlytackle with unique challenges have a diverse condition from the implicit assumptions of leading countries. India being one of these countries that many of its Information Technology implementation failures take place. Micro small and medium enterprises(MSME) can be considered as vital part of the Indian economy contributing over 45% of industrial production and around 40% of the totalexports. As per International Data Corporation (IDC) the awareness and the rate of adoption of ERP are highest among large organizations but it is the MSMEs that would fuel the future growth. In India there is a big market for ERP for MSMEs, given that there are over 20,000 small and mid size industries.Identifying the critical success factors of Enterprise Application implementation have been subjected t o substantial in-depth research, however while going through the literature it seems as such there is no comprehensive study has taken place that identifies the critical failure factors of Enterprise Application implementation incontext to Indian micro enterprises. The purpose of this paper is to present the findings of a study which is based on the resul ts of a comprehensive compilation of literature and subsequent analysis of ERP implementation failure factors in context to Indian Micro, Small and Mediu m scale Enterprises (MSMEs). This paper attempts to empirically assess which factors are most criticalin the ERP implementation process from the perspective of the Indian MSMEs.
N‐Acetylcysteine reduces hyperacute intermittent hypoxia‐induced sympathoexcitation in human subjects

What is the central question of this study? This study evaluated the following central question: does N‐acetylcysteine (N‐AC), an antioxidant that readily penetrates the blood–brain barrier, have the capability to reduce the increase in sympathetic nerve activity observed during hyperacute intermittent hypoxia? What is the main finding and its importance? We demonstrate that N‐AC decreases muscle sympathetic nerve activity in response to hyperacute intermittent hypoxia versus placebo control. This finding suggests that antioxidants, such as N‐AC, have therapeutic potential in obstructive sleep apnoea.
Kinetics of Ca2+ binding to parvalbumin in bovine chromaffin cells: implications for [Ca2+] transients of neuronal dendrites

1 κS1. The effect of parvalbumin (PV) on [Ca2+] transients was investigated by perfusing adrenal chromaffin cells with fura‐2 and fluorescein isothiocyanate (FITC)‐labelled PV. As PV diffused into cells, the decay of [Ca2+] transients was transformed from monophasic into biphasic. The proportion of the initial fast decay phase increased in parallel with the fluorescence intensity of FITC, indicating that PV is responsible for the initial fast decay phase. 2 The relationship between the fast decay phase and the [Ca2+] level was investigated using depolarizing trains of stimuli. Within a train the relative amplitude of the fast decay phase was inversely dependent on the [Ca2+] level preceding a given stimulus. 3 Based on these observations, we estimated the Ca2+ binding ratio of PV (κP), the apparent dissociation constant of PV for Ca2+ (Kdc,app), and the unbinding rate constant of Ca2+ from PV (kc‐) in the cytosol of chromaffin cells. Assuming free [Mg2+] to be 0.14 mm, we obtained values of 51.4 ± 2.0 nm (n= 3) and 0.95 ± 0.026 s−1 (n= 3), for Kdc,app and kc‐, respectively. 4 With the parameters obtained in the perfusion study, we simulated [Ca2+] transients, using two different Ca2+ extrusion rates (γ) – 20 and 300 s−1– which represent typical values for chromaffin cells and neuronal dendrites, respectively. The simulation indicated that Ca2+ is pumped out before it is equilibrated with PV, when γ is comparable to the equilibration rates between PV and Ca2+, resulting in the fast decay phase of a biexponential [Ca2+] transient. 5 From these results we conclude that Ca2+ buffers with slow kinetics, such as PV, may cause biexponential decays in [Ca2+] transients, thereby complicating the analysis of endogenous Ca2+ binding ratios (κS) based on time constants. Nevertheless, estimates of κS based on Ca2+ increments provide reasonable estimates for Ca2+ binding ratios before equilibration with PV.
Disclosure and health: Enhancing the benefits of trauma writing through response training

DISCLOSURE AND HEALTH: ENHANCING THE BENEFITS OF TRUAMA WRITING THROUGH RESPONSE TRAINING By: Andrea Konig, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University Virginia Commonwealth University, 2011. Major Director: Scott R. Vrana, Ph.D. Professor of Psychology Department of Psychology Writing about a personal traumatic event has been found to have psychological and physical health benefits. Focusing on traumatic memories in writing may be a form of exposure. In imagery exposure and trauma writing, greater physiological reactivity was predictive of better outcomes. Given the importance of physiological output in emotional processing, response training was developed and found to be effective in increasing appropriate physiological reactivity in imagery exposure. If response training amplifies physiological reactivity and the benefits of writing, the hypothesis that writing is a form of exposure would be strengthened, and training may be a valuable tool to improve the efficacy of psychotherapy approaches that use writing as a form of exposure. The present study examined whether response training enhances the benefits of trauma writing. In this study, participants wrote for 20 minutes on three occasions about a personal traumatic event (n = 113) or a trivial topic (n = 133) and received response imagery training (n = 79), stimulus imagery training (n = 84) or no training (n = 83). Heart rate and skin conductance were recorded in sessions one and three throughout a 10-minute baseline, writing, and a ten-minute recovery period. Self-reported trauma symptoms and emotion were assessed in each session. One month after completing the sessions, participants completed follow-up assessments of psychological and physical health outcomes. As predicted, trauma writing elicited greater physiological reactivity and self-reported trauma symptoms and emotion than neutral writing. Response training amplified physiological reactivity to trauma writing more than neutral writing, without amplifying levels of self-reported emotion or trauma symptoms. The physiological reactivity and self-reported emotion elicited by trauma writing habituated across sessions and response training enhanced these effects. Finally, increased heart rate predicted better outcomes for all trauma writers; however, response trained trauma writers who evidenced greater heart rate showed the greatest reductions in trauma, depression and physical illness symptoms at follow-up. These results support previous research which found that greater physiological reactivity was predictive of writing outcomes. The findings are the first to demonstrate that response training facilitates emotional processing and thus may be a beneficial adjunct to trauma writing.
Timing of gastrostomy insertion in children with a neurodisability: a cross-sectional study of early versus late intervention

Objectives The aim of the study was to assess whether gastrostomy placement before 18 months of age results in a greater increase in z-score for weight and to assess whether admission rates were reduced postgastrostomy in this age group. Design Retrospective cross-sectional study. Setting Single-centre secondary care District General Hospital. Participants All children with a neurodisability with a gastrostomy in situ in September 2011 were included. Those with primary neoplasia and undergoing chemo or radiotherapy or being palliated for an aggressive neurodegenerative disorder were excluded. Those with cystic fibrosis, primary congenital heart disease or Inflammatory bowel disease were also excluded. Forty-one children underwent final analysis. Twenty-four children underwent gastrostomy insertion less than 18 months and 17 children were older than 18 months. Primary and secondary outcome measures Primary outcome was z-scores for weight immediately pregastrostomy and 12 months postgastrostomy. Secondary outcomes were hospital admission rates pregastrostomy and postgastrostomy. Values were compared for those with gastrostomy insertion less than or equal to 18 months against those older than 18 months at insertion. Results Z-score for weight increased significantly in both age groups. There was significantly increased mean difference in the z-score for weight of +1.33 pregastrostomy and postgastrostomy in the less than 18 months age group as compared with an increased mean difference in the z-score for weight of +0.45 in the older age group (p=0.021). There was no significant difference in the admission rates postgastrostomy insertion in either age group. Conclusions Gastrostomy insertion before 18 months of age results in greater z-score for weight gain in children with a neurodisability. This conclusion is limited by the lack of height and skin-fold thickness measurements. Further long-term matched control studies are required to determine the neurodevelopmental and clinical benefit of early gastrostomy placement in such children.
Gulf War illness: an overview of events, most prevalent health outcomes, exposures, and clues as to pathogenesis

Abstract Introduction: During or very soon after the 1990–1991 Persian Gulf War, veterans of the conflict began to report symptoms of illness. Common complaints included combinations of cognitive difficulties, fatigue, myalgia, rashes, dyspnea, insomnia, gastrointestinal symptoms and sensitivity to odors. Gradually in the USA, and later in the UK, France, Canada, Denmark and Australia, governments implemented medical assessment programs and epidemiologic studies to determine the scope of what was popularly referred to as “the Gulf War syndrome”. Attention was drawn to numerous potentially toxic deployment-related exposures that appeared to vary by country of deployment, by location within the theater, by unit, and by personal job types. Identifying a single toxicant cause was considered unlikely and it was recognized that outcomes were influenced by genetic variability in xenobiotic metabolism. Methods: Derived from primary papers and key reports by the Research Advisory Committee on Gulf War Veterans’ Illnesses and the Institute of Medicine, a brief overview is presented of war related events, symptoms and diagnostic criteria for Gulf War illness (GWV), some international differences, the various war-related exposures and key epidemiologic studies. Possible exposure interactions and pathophysiologic mechanisms are discussed. Results: Exposures to pyridostigmine bromide, pesticides, sarin and mustard gas or combinations thereof were most associated with GWI, especially in some genotype subgroups. The resultant oxidant stress and background exposome must be assumed to have played a role. Conclusion: Gulf War (GW) exposures and their potential toxic effects should be considered in the context of the human genome, the human exposome and resultant oxidant stress to better characterize this unique environmentally-linked illness and, ultimately, provide a rationale for more effective interventions and future prevention efforts.
Patient-centred care, health behaviours and cardiovascular risk factor levels in people with recently diagnosed type 2 diabetes: 5-year follow-up of the ADDITION-Plus trial cohort

Objective To examine the association between the experience of patient-centred care (PCC), health behaviours and cardiovascular disease (CVD) risk factor levels among people with type 2 diabetes. Design Population-based prospective cohort study. Setting 34 general practices in East Anglia, UK, delivering organised diabetes care. Participants 478 patients recently diagnosed with type 2 diabetes aged between 40 and 69 years enrolled in the ADDITION-Plus trial. Main outcome measures Self-reported and objectively measured health behaviours (diet, physical activity, smoking status), CVD risk factor levels (blood pressure, lipid levels, glycated haemoglobin, body mass index, waist circumference) and modelled 10-year CVD risk. Results Better experiences of PCC early in the course of living with diabetes were not associated with meaningful differences in self-reported physical activity levels including total activity energy expenditure (β-coefficient: 0.080 MET h/day (95% CI 0.017 to 0.143; p=0.01)), moderate-to-vigorous physical activity (β-coefficient: 5.328 min/day (95% CI 0.796 to 9.859; p=0.01)) and reduced sedentary time (β-coefficient: −1.633 min/day (95% CI −2.897 to −0.368; p=0.01)). PCC was not associated with clinically meaningful differences in levels of high-density lipoprotein cholesterol (β-coefficient: 0.002 mmol/L (95% CI 0.001 to 0.004; p=0.03)), systolic blood pressure (β-coefficient: −0.561 mm Hg (95% CI −0.653 to −0.468; p=0.01)) or diastolic blood pressure (β-coefficient: −0.565 mm Hg (95% CI −0.654 to −0.476; p=0.01)). Over an extended follow-up of 5 years, we observed no clear evidence that PCC was associated with self-reported, clinical or biochemical outcomes, except for waist circumference (β-coefficient: 0.085 cm (95% CI 0.015 to 0.155; p=0.02)). Conclusions We found little evidence that experience of PCC early in the course of diabetes was associated with clinically important changes in health-related behaviours or CVD risk factors. Trial registration number ISRCTN99175498; Post-results.
SU-8 based piezoresistive mechanical sensor

We present the first SU-8 based piezoresistive mechanical sensor. Conventionally, silicon has been used as a piezoresistive material due to its high gauge factor and thereby high sensitivity to strain changes in a sensor. By using the fact that SU-8 is much softer than silicon and that a gold resistor is easily incorporated in SU-8, we have proven that a SU-8 based cantilever sensor is almost as sensitive to stress changes as the silicon piezoresistive cantilever. We demonstrate the chip fabrication, and characterization with respect to sensitivity, noise and device failure.
Bile salts-containing vesicles: promising pharmaceutical carriers for oral delivery of poorly water-soluble drugs and peptide/protein-based therapeutics or vaccines

Abstract Most of the new drugs, biological therapeutics (proteins/peptides) and vaccines have poor performance after oral administration due to poor solubility or degradation in the gastrointestinal tract (GIT). Though, vesicular carriers exemplified by liposomes or niosomes can protect the entrapped agent to a certain extent from degradation. Nevertheless, the harsh GIT environment exemplified by low pH, presence of bile salts and enzymes limits their capabilities by destabilizing them. In response to that, more resistant bile salts-containing vesicles (BS-vesicles) were developed by inclusion of bile salts into lipid bilayers constructs. The effectiveness of orally administrated BS-vesicles in improving the performance of vesicles has been demonstrated in researches. Yet, these attempts did not gain considerable attention. This is the first review that provides a comprehensive overview of utilizing BS-vesicles as a promising pharmaceutical carrier with a special focus on their successful applications in oral delivery of therapeutic macromolecules and vaccines. Insights on the possible mechanisms by which BS-vesicles improve the oral bioavailability of the encapsulated drug or immunological response of entrapped vaccine are explained. In addition, methods adopted to prepare and characterize BS-vesicles are described. Finally, the gap in the scientific researches tackling BS-vesicles that needs to be addressed is highlighted.
A promising jail reentry program revisited: results from a quasi-experimental design

Prisoner reentry remains a significant challenge for the criminal justice system with millions of offenders returning to society each year from the nation’s prisons and jails. Employment, housing, and access to substance abuse and mental health treatment are common, often unmet, challenges for the returning offender. In response, state and local jurisdictions have implemented reentry programming designed to assist in the transition from incarceration to the community. While most of these programs have targeted offenders in prisons, a growing number of local jurisdictions have implemented reentry initiatives through federal funding. This study examines the second cohort (2011–2013) of the Auglaize County (OH) transition program (ACT), a BJA-designated ‘promising’ reentry program. This evaluation sought to determine if the program maintained its positive impact on participant recidivism. Findings indicate that the treatment group had significantly lower rates of rearrest and probation violations at the bivariate level, but that these results did not hold for rearrest after the inclusion of relevant control variables in the multivariate analysis. Participation remained significantly associated with reduced probation violations at the multivariate level.
Relationship between morphoelectrotonic properties of motoneuron dendrites and their trajectory

The distribution and geometry of the dendritic trees of spinal motoneurons obey several well‐established rules. Some of these rules are based on systematic relationships between quantitative geometrical features (e.g., total dendritic length) and the three‐dimensional trajectory followed by dendrites from their origin to their termination. Because dendritic geometry partially determines the transmission of current and voltage signals generated by synapses on the dendritic tree, our goal was to compare the efficacy of signal transmission by dendritic trajectories that followed different directions. To achieve this goal, we constructed detailed compartmental models of the dendritic trees of three intracellularly stained biventer cervicis/complexus (BCCM) motoneurons and calculated the electronic properties of 361 dendritic paths. Each trajectory was classified according to its orientation, e.g., rostral, rostral‐dorsal‐lateral. The attenuation of current and voltage signals en route to the soma was strongly related to trajectory orientation. Trajectories with similar attenuation factors formed functional subunits that were arranged in distinct domains within the ventral horn. Changes in Rm or Ri had little effect on which trajectories belonged to each functional subunit. However, differences in the efficacy of signal transmission between subunits increased during high network activity (mimicked by decreases in Rm). The most efficient subunit delivered two times more current and four times more voltage to the soma than the least efficient subunit. These results indicate that the input‐output properties of motoneurons depend on the direction of the path taken by dendrites from their origin at the cell body to their terminals. J. Comp. Neurol. 473:562–581, 2004. © 2004 Wiley‐Liss, Inc.