Miracle-dz/UniFAR-FTUs huggingface dataset:
Realities regarding the student perception of the education and development entrepreneurial spirit needs in the context of the actual economy. Study case

The development of the entrepreneurial skills has become an important source of economical growth because this can stimulate innovation and can successfully lead towards innovative and flourishing businesses which generate an economical growth in that specific region. This is much true as entrepreneurship is a mindset that centers on the creative discovery and the pursuit of opportunities, even when resources are scarce. In this article there will be presented the results of a comparative analyse after a questionnaire based survey was conducted in order to see the entrepreneurship spirit, entrepreneurial intentions and the entrepreneurial perceptions among students from West University of Timisoara, Faculty of Management (considered business studies) and students from Faculty of Pedagogy (considered non-business studies).
Potential Benefits from Sharing Rainwater Storages Depending on Characteristics in Demand

A rainwater harvesting system (RWHS) is an alternative water resource that collects and stores rainwater from rooftops. It helps smooth out variations in water supply and sustainable water resources management. In this study, we investigated the potential benefits from sharing RWHS with nearby neighbors in a community. We introduced different mean, variance, and correlation in water demand for each water user. A simple case of a community composed of four prospective users is introduced to investigate the benefit from sharing RWHSs. Using the historical rainfall records from four catchments in South Korea, a storage-reliability-yield analysis is applied to obtain the required storage and corresponding reliability for a given yield ratio. The results indicate that the required total storage is reduced when RWHSs are shared among users and the rate of reduction is proportional to the degree of sharing. The required total storage was reduced down to 61% compared to the original storage when RWHSs are shared for a target reliability of 80%. The benefit from sharing also depends on the demands, which are different among users. Test cases with different means and variances as well as correlation disclose the conditions when the benefit from sharing RWHSs is maximized. The result showed that difference in mean and variance additionally reduces the required storage up to 3% and correlation in demand also as much affects the required storage.
Imbalanced Multiple Noisy Labeling

It can be easy to collect multiple noisy labels for the same object via Internet-based crowdsourcing systems. Labelers may have bias when labeling, due to lacking expertise, dedication, and personal preference. These cause Imbalanced Multiple Noisy Labeling. In most cases, we have no information about the labeling qualities of labelers and the underlying class distributions. It is important to design agnostic solutions to utilize these noisy labels for supervised learning. We first investigate how imbalanced multiple noisy labeling affects the class distributions of training sets and the performance of classification. Then, an agnostic algorithm Positive LAbel frequency Threshold (PLAT) is proposed to deal with the imbalanced labeling issue. Simulations on eight UCI data sets with different underlying class distributions show that PLAT not only effectively deals with the imbalanced multiple noisy labeling problems that off-the-shelf agnostic methods cannot cope with, but also performs nearly the same as majority voting under the circumstances without imbalance. We also apply PLAT to eight real-world data sets with imbalanced labels collected from Amazon Mechanical Turk, and the experimental results show that PLAT is efficient and better than other ground truth inference algorithms.
Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility

Changes in protein subdomains through alternative splicing often modify protein‐protein interactions, altering biological processes. A relevant example is that of the stress‐induced up‐regulation of the acetylcholinesterase (AChE‐R) splice variant, a common response in various tissues. In germ cells of male transgenic TgR mice, AChE‐R excess associates with reduced sperm differentiation and sperm counts. To explore the mechanism(s) by which AChE‐R up‐regulation affects spermatogenesis, we identified AChE‐R's protein partners through a yeast two‐hybrid screen. In meiotic spermatocytes from TgR mice, we detected AChE‐R interaction with the scaffold protein RACK1 and elevated apoptosis. This correlated with reduced scavenging by RACK1 of the pro‐apoptotic TAp73, an outcome compatible with the increased apoptosis. In contrast, at later stages in sperm development, AChE‐R's interaction with the glycolytic enzyme enolase‐α elevates enolase activity. In transfected cells, enforced AChE‐R excess increased glucose uptake and adenosine tri‐phosphate (ATP) levels. Correspondingly, TgR sperm cells display elevated ATP levels, mitochondrial hyperactivity and increased motility. In human donors' sperm, we found direct association of sperm motility with AChE‐R expression. Interchanging interactions with RACK1 and enolase‐α may hence enable AChE‐R to affect both sperm differentiation and function by participating in independent cellular pathways.
Pharmacist's attitudes towards dispensing errors: their causes and prevention.

OBJECTIVE To assess the attitudes of pharmacists towards the issue of dispensing errors. METHOD A postal survey was undertaken among all Tasmanian-registered pharmacists residing in Australia. The anonymous questionnaire sought opinions on whether the risk of dispensing errors and the actual numbers of errors are increasing, the major factors contributing to the occurrence of dispensing errors, factors that can best minimize the risk of dispensing errors, the number of prescription items that one pharmacist can safely dispense in a day and whether Australia should have a regulatory maximum dispensing load, and an estimation of the number of recent errors at the pharmacist's workplace. RESULTS Completed questionnaires were received from 209 pharmacists (50% response rate). Most pharmacists (82%) believed that the risk of dispensing errors is increasing. The principal contributing factors nominated were: high prescription volumes, pharmacist fatigue, pharmacist overwork, interruptions to dispensing, and similar or confusing drug names. The main factors identified as being important in reducing the risk of dispensing errors were: having mechanisms for checking dispensing procedures, having a systematic dispensing workflow, checking the original prescription (duplicate) when dispensing repeats, improving the packaging and labelling of drug products, having drug names that are distinctive, counselling patients at the time of supply, keeping one's knowledge of drugs up-to-date, avoiding interruptions, reducing workloads on pharmacists, improving doctors' handwriting, and privacy when counselling patients. Most pharmacists (72%) stated that they were aware of dispensing errors that had left the pharmacy undetected, in their place of practice during the past 6 months. The median number of such dispensing errors that they were aware of was three. A median of 150 was nominated as the maximum number of prescription items that can be safely dispensed per 9-h day (i.e. 17 items per hour) by or in the presence of one pharmacist. Most pharmacists (58%) stated that there should be a regulatory guideline for the safe dispensing load in Australia. CONCLUSION Dispensing errors are occurring in numbers well above reports to regulatory authorities or professional indemnity insurance companies, and seem to be accepted as part of practice. High prescription volumes, pharmacist fatigue and overwork appear to be important factors. The profession needs to be proactive and standards must be set appropriately high (i.e. zero error tolerance).
A distributed deterministic help scheme to improve the system fault tolerance

This paper proposes some methods to improve the fault-tolerance in distributed systems specifically in deterministic situations by distributed decision-making and coordination. Providing a distributed system with fault tolerance is a feasible but hard problem due to the intrinsic aspects of such systems such as: independency, unpredictability and communication problem. A multi-agent system as an instance of distributed system, can handle different kinds of fault by using traditional fault tolerance techniques. But what focused in this paper are agent-based techniques. In fact proposed methods are based on agent-based help provision by distributed cooperation among helper agents. The helpers try to tune their normal roles such that they can undertake the faulty agents' tasks too. These helpers go through a sub-optimal task selection algorithm, to decide whom to help. It is important to remark that there is no explicit interaction; instead they coordinate their decisions implicitly by adopting the most appropriate task in terms of their speed, relative reliability and the task's criticality coefficient. Proposed ideas are tested on a DCS-like tested to improve its fault tolerance. The results illustrate the effectiveness of the approaches in comparison to the case of no help situation and the case of using purely redundant components.
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells

Ampelopsin (AMP), a plant flavonoid, has been reported to inhibit cell growth and/or induce apoptosis in various types of tumor. The aim of the present study was to assess the apoptosis-inducing activity of AMP in A549 human lung adenocarcinoma epithelial cells and the associated underlying mechanism. A549 cells were incubated with different concentrations of AMP in culture medium. Cell growth and apoptosis were evaluated by MTT assay and Annexin V/propidium iodide double staining and flow cytometry, respectively. In addition, western blotting and reverse transcription quantitative polymerase chain reaction analysis were used to examine the time-dependent changes in protein expression. Certain changes in apoptotic protein expression were detected following exposure to AMP, including X-linked inhibitor of apoptosis protein release, reduced B-cell lymphoma 2, myeloid cell leukemia 1 and survivin expression levels, increased Bcl-2-associated X protein expression levels and cleaved-poly ADP ribose polymerase expression. The results revealed that AMP was a potent inhibitor of A549 cell proliferation. The c-Myc/S-phase kinase-associated protein 2 (Skp2) and histone deacetylase (HDAC)1/2 pathways were found to exert an important role in AMP-induced A549 cell apoptosis, as increased levels of c-Myc mRNA and reduced levels of c-Myc/Skp2 and HDAC1 and 2 proteins following AMP treatment were observed. The levels of F-box and WD repeat-containing protein 7α (Fbw7α), Fbw7β, Fbw7γ, phosphorylated-(p−)c-Myc (Thr58) and glycogen synthase kinase 3β (GSK3β) proteins involved in c-Myc ubiquitin-dependent degradation were also analyzed. Following exposure to AMP, the expression levels of Fbw7α, Fbw7γ and GSK3β were reduced and p-c-Myc (Thr58) expression levels were increased. The results suggest that AMP exerts an anticancer effect, which is associated with the degradation of c-Myc, Skp2 and HDAC1 and 2. The ability of AMP to induce apoptosis independently of Fbwα and Fbw7γ suggests a possible use in drug-resistant cancer associated with Fbw7 deficiency. Understanding the exact underlying mechanism requires further investigation of the association between c-Myc and Fbw7α/γ reversal, and analysis of whether Thr58 phosphorylation of c-Myc is dependent on GSK3β.
A home-based care model for outpatient cardiac rehabilitation based on mobile technologies

Cardiac rehabilitation programs offer effective means to prevent recurrence of a cardiac event. However, poor uptake of current programs have been reported globally. Home based model is considered as an alternative to avoid barriers related to hospital based programs. The challenge in a home based program is to re-establish the link between the patient and clinician regardless of their location. Mobile phones and internet technologies can potentially be used to enable a comprehensive home based care model. We developed tools and integrated model for home based cardiac rehabilitation based on a mobile phone with integrated accelerometer to measure physical exercise and diary to collect information on physiological risk factors and other health information. Video and teleconferencing are used for mentoring sessions and educational multimedia content is transferred via messaging systems to the patients phone to be viewed on demand. The model can be extended to management of other chronic conditions.
National Annuity Markets: Features and Implications

This paper describes a number of national annuity markets, the types of products typically available, the demand for these products, the value for money on offer and the dynamics of the supply side. It explores supply and demand characteristics, asking what the main forces are that drive these dynamics and how they might be recognised and responded to by policymakers. Marches nationaux des rentes viageres : caracteristiques et implications Ce papier decrit un certain nombre de marches nationaux des rentes viageres, le type de produits disponibles, la demande pour ces produits, la valeur de l‘argent sur l‘offre et la dynamique de la demande. Il explore les caracteristiques de l‘offre et de la demande, recherchant quelles sont les forces guidant cette dynamique et comment elles pourraient etre reconnues et traitees par les responsables politiques.
Development of a Test of Suprathreshold Acuity in Noise in Brazilian Portuguese: A New Method for Hearing Screening and Surveillance

This paper describes the development of a speech-in-noise test for hearing screening and surveillance in Brazilian Portuguese based on the evaluation of suprathreshold acuity performances. The SUN test (Speech Understanding in Noise) consists of a list of intervocalic consonants in noise presented in a multiple-choice paradigm by means of a touch screen. The test provides one out of three possible results: “a hearing check is recommended” (red light), “a hearing check would be advisable” (yellow light), and “no hearing difficulties” (green light) (Paglialonga et al., Comput. Biol. Med. 2014). This novel test was developed in a population of 30 normal hearing young adults and 101 adults with varying degrees of hearing impairment and handicap, including normal hearing. The test had 84% sensitivity and 76% specificity compared to conventional pure-tone screening and 83% sensitivity and 86% specificity to detect disabling hearing impairment. The test outcomes were in line with the degree of self-perceived hearing handicap. The results found here paralleled those reported in the literature for the SUN test and for conventional speech-in-noise measures. This study showed that the proposed test might be a viable method to identify individuals with hearing problems to be referred to further audiological assessment and intervention.
Coupled Quantum-Scattering Modeling of Thermoelectric Properties of Si / Ge / Si Quantum Well Superlattice

Confined structures presumably offer enhanced performance of thermoelectric devices. 1) Interfaces and boundaries create scattering sites for phonons, which reduces the thermal conductivity. 2) Reduced dimensionality increases the local density of states near the Fermi level, which increases the Seebeck coefficient. From these two phenomena, the net effect should be an increase in ZT, the performance parameter used to evaluate different materials and structures. These effects have been measured and modeled, but none of the models attempts to quantify the electron-phonon coupled effects particularly in the regime where quantum and scattering influences are found. Using the non-equilibrium Green's function (NEGF) approach, quantum wells composed of Si and Ge are studied and the important physics isolated. Results show a competing effect between the decrease in the electrical conductivity due to scattering with the increase in electrical conductivity with doping, leading to 77% decrease in the value of the power factor for the case of electron-optical phonon scattering.
Socialbots: voices from the fronts

The Social Mediator forum was created to bridge the gaps between the theory and practice of social media research and development. The articles are intended to promote greater awareness of new insights and experiences in the rapidly evolving domain of social media, some of which may influence perspectives and approaches in the more established areas of human-computer interaction. Each article in the forum is made up of several short contributions from people representing different perspectives on a particular topic. Previous installments of this forum have woven together diverse perspectives on the ways that social media is transforming relationships among different stakeholders in the realms of healthcare and government. The current article highlights some of the ways social robots (socialbots)---programs that operate autonomously on social networking sites---are transforming relationships within those sites, and how these transformations may more broadly influence relationships among people and organizations in the future. A recent article in Communications of the ACM called "The Social Life of Robots" reported that "researchers have started to explore the possibilities of 'social' machines capable of working together with minimal human supervision" [1]. That article illuminates recent developments involving interactions between humans and robots in the physical world; this article focuses on the interactions between humans and robots in the virtual world. Our authors are exploring and expanding the frontiers of designing, deploying, and analyzing the behavior and impact of robots operating in online social networks, and they have invited a number of other frontierspeople to share some of their insights, experiences, and future expectations for social robotics.
Monkeys (Macaca mulatta and Cebus apella) and Human Adults and Children (Homo sapiens) Enumerate and Compare Subsets of Moving Stimuli Based on Numerosity

(2011). Monkeys (Macaca mulatta and Cebus apella) and human adults and children (Homo sapiens) enumerate and compare subsets of moving stimuli based on numerosity. Frontiers in Psychology, 2:61. Within the set of studies that involve judgments between sets of stimuli, however, there must be a distinction made between those studies that require animals to discriminate the number of items from those studies that afford other stimulus properties that could successfully guide performance. For example, many studies have used homogeneous food items as the stimuli to be discriminated and this allows the animal to make the quantity judgment using the total amount of stimuli rather than the number of stimuli. Other studies control for non-numerical properties, so that quantity judgments must be made on the basis of the number of items in sets, and some species succeed in these tests showing that their judgments are truly numerical and could be rightly called numerousness judgments (e. In some cases, the numerical processing of non-human animals has been directly compared to that of humans on the same task. For example, monkeys and human children have shown some similarities in the way they process numerical stimuli in a bisection task, in which they had to classify stimuli as being of large or small numbers (Jordan and Brannon, 2006b; Beran et al., 2008). Humans and monkeys also show similarities in their ordinal sequencing of stimuli based on numerical properties (e.g., Cantlon and Brannon, 2006). They show semantic congruity effects where they are faster to choose the correct response when there is congruity between the task rule (such as " choose smaller " or " choose larger ") and the magnitude of the choice sets (small or large numbers of dots; see
VLT UVES Observations of Interstellar Molecules and Diffuse Bands in the Magellanic Clouds

We discuss the abundances of interstellar CH, CH+, and CN in the Magellanic Clouds, derived from spectra of seven SMC and 13 LMC stars obtained (mostly) with the VLT UVES. CH and/or CH+ have now been detected toward three SMC and nine LMC stars; CN is detected toward Sk 143 (SMC) and Sk -67 2 (LMC). These data represent nearly all the optical detections of these molecular species in interstellar media beyond the Milky Way. In the LMC, the CH/H2 ratio is comparable to that found for diffuse Galactic molecular clouds in four sight lines but is lower by factors of 2.5-4.0 in two others. In the SMC, the CH/H2 ratio is comparable to the local Galactic value in one sight line but is lower by factors of 10-15 in two others. The abundance of CH in the Magellanic Clouds thus appears to depend on local physical conditions and not just on metallicity. In both the SMC and the LMC, the observed relationships between the column density of CH and those of CN, CH+, Na I, and K I are generally consistent with the trends observed in our Galaxy. Using existing data for the rotational populations of H2 in these sight lines, we estimate temperatures, radiation field strengths, and local hydrogen densities for the diffuse molecular gas. The inferred temperatures range from about 45 to 90 K, the radiation fields range from about 1 to 900 times the typical local Galactic field, and the densities (in most cases) lie between 100 and 600 cm-3. Densities estimated from the observed N(CH), under the assumption that CH is produced via steady state gas-phase reactions, are considerably higher than those derived from H2. Much better agreement is found by assuming that the CH is made via the (still undetermined) process(es) responsible for the observed CH+. A significant fraction of the CH and CH+ in diffuse molecular material in the SMC and LMC may be produced in photon-dominated regions. The excitation temperature obtained from the populations of the two lowest CN rotational levels toward Sk -67 2 is quite consistent with the temperature of the cosmic microwave background radiation measured with COBE. Toward most of our targets, the UVES spectra also reveal absorption at velocities corresponding to the Magellanic Clouds ISM from several of the strongest of the diffuse interstellar bands (DIBs; at 5780, 5797, and 6284 Å). On average, the three DIBs are weaker by factors of 7-9 (LMC) and about 20 (SMC), compared to those typically observed in Galactic sight lines with similar N(H I), presumably due to the lower metallicities and stronger radiation fields in the LMC and SMC. The three DIBs are also weaker (on average, but with some exceptions), by factors of order 2-6, relative to E(B-V), N(Na I), and N(K I) in the Magellanic Clouds. The detection of several of the so-called C2 DIBs toward Sk 143 and Sk -67 2 with strengths similar to those in comparable Galactic sight lines, however, indicates that no single, uniform scaling factor (e.g., one related to metallicity) applies to all DIBs (or for all sight lines) in the Magellanic Clouds.