Miracle-dz/UniFAR-FTUs huggingface dataset:
B-Ephrin Reverse Signaling Is Required for NMDA-Independent Long-Term Potentiation of Mossy Fibers in the Hippocampus

The mossy fiber to CA3 pyramidal neuron synapse in the hippocampus displays an atypical form of NMDA receptor-independent long-term potentiation (LTP). Plasticity at this synapse is expressed in the presynaptic terminal as an elevated probability of neurotransmitter release. However, evidence indicates that postsynaptic mechanisms and trans-synaptic signaling through an association between postsynaptic EphB receptors and presynaptic B-ephrins are necessary for the induction of LTP. Here we show that ephrin-B3 protein is highly expressed in mossy fiber axons and terminals. There are specific deficits in mossy fiber LTP in mice in which the cytoplasmic C-terminal signaling domain of the ephrin-B3 protein is replaced with β-galactosidase. These deficits are not observed in ephrin-B3 null mutant mice because of functional redundancy by virtue of other B-ephrins. These results indicate that B-ephrin reverse signaling into the presynaptic mossy fiber bouton is required for the induction of NMDA receptor-independent LTP at this synapse.
The longitudinal relation between positive self-defining memories, self-esteem and depressive symptoms among the general population

Objective: Previous research suggested that there is a relationship between positive self-defining memories, self-esteem and depressive symptoms. This research aims to investigate the relationship between those variables. Method: In 2012, a longitudinal questionnaire study was carried out with three measurements of self-defining memories and one measurement of self-esteem and depressive symptoms among 1193 Dutch participants (51,6 % female, mean age: 59 years). The relationship between these variables were analyzed with a mediation analyses. Results: Positive self-defining memories over time were related to self-esteem. Positive self-defining memories over time were related to depressive symptoms. Self-esteem was related to depressive symptoms and the relationship of positive self-defining memories with depressive symptoms was partially mediated by self-esteem. Conclusion: The results indicate that positive self-defining memories are related to self-esteem which in turn is related to depressive symptoms. Self-esteem accounts for some, but not all, of the relationship between positive self-defining memories and depressive symptoms. The findings of this research support models and theories about the relationship between self-defining memories, self-esteem and depressive symptoms. However, further research is needed in order to make a causal statement about the relationship between positive self-defining memories, self-esteem and depressive symptoms. The current results support the theory of the upward spiral of depressive symptoms. Moreover, positive self-defining memories could be used as an approach to prevent a depressive episode.
Bell-type quantum field theories

In his paper (1986 Beables for quantum field theory Phys. Rep. 137 49? 54) John S Bell proposed how to associate particle trajectories with a lattice quantum field theory, yielding what can be regarded as a |? |2-distributed Markov process on the appropriate configuration space. A similar process can be defined in the continuum, for more or less any regularized quantum field theory; we call such processes Bell-type quantum field theories. We describe methods for explicitly constructing these processes. These concern, in addition to the definition of the Markov processes, the efficient calculation of jump rates, how to obtain the process from the processes corresponding to the free and interaction Hamiltonian alone, and how to obtain the free process from the free Hamiltonian or, alternatively, from the one-particle process by a construction analogous to 'second quantization'. As an example, we consider the process for a second quantized Dirac field in an external electromagnetic field.
Correlation between Emotional Quotient and Caring Behavior of Nurses in Adult Inpatient Ward

Caring is an important thing for a nurse in delivering nursing care to the patient in the form of caring behavior. Emotional quotient is an ability of a person to recognize feelings of self and others. The purpose of this study was to determine the relationship of emotional quotient and caring behavior of nurses in adult inpatient wards at dr. Dradjat Prawiranegara Serang Hospital. This study was correlational study with cross-sectional design. 63 nurses were involved as respondents in this study. The results showed that most of nurses show caring (54%), while most of them showed low category of emotional quotient (52.4%). Chi-square test showed that there was a significant correlation between emotional quotient and caring behavior of nurses (p-value 0.001), in which the odd value ratio was 9.2. This study encourages hospital to present a training of improving emotional quotient and caring behavior of nurses to their patients.
Some radio implementation challenges in 3G-LTE context

This paper addresses some radio implementation related RF impairment issues in long-term evolution (LTE) of 3G mobile radio system context, with special emphasis on the so-called I/Q imbalance and the resulting mirror-frequency interference problems. The relative roles of transmitter and receiver mirror-frequency attenuation characteristics on the overall link and system performance are discussed and analyzed, with most focus on the LTE uplink. Furthermore, we demonstrate that the limited mirror-frequency attenuation of the transmitter and receiver analog front-ends can be greatly improved using proper DSP techniques. Realistic example case studies in LTE uplink are given, demonstrating the feasibility and efficiency of such I/Q compensation or calibration techniques. Based on the obtained results, analog front-end attenuations typically around 25-40 dB can easily be improved up to 50-80 dB range or so, under very reasonable assumptions on the implementation resources allocated to the calibration and compensation circuitries.
Land, irrigation water, greenhouse gas, and reactive nitrogen burdens of meat, eggs, and dairy production in the United States

Significance Livestock-based food production is an important and pervasive way humans impact the environment. It causes about one-fifth of global greenhouse gas emissions, and is the key land user and source of water pollution by nutrient overabundance. It also competes with biodiversity, and promotes species extinctions. Empowering consumers to make choices that mitigate some of these impacts through devising and disseminating numerically sound information is thus a key socioenvironmental priority. Unfortunately, currently available knowledge is incomplete and hampered by reliance on divergent methodologies that afford no general comparison of relative impacts of animal-based products. To overcome these hurdles, we introduce a methodology that facilitates such a comparison. We show that minimizing beef consumption mitigates the environmental costs of diet most effectively. Livestock production impacts air and water quality, ocean health, and greenhouse gas (GHG) emissions on regional to global scales and it is the largest use of land globally. Quantifying the environmental impacts of the various livestock categories, mostly arising from feed production, is thus a grand challenge of sustainability science. Here, we quantify land, irrigation water, and reactive nitrogen (Nr) impacts due to feed production, and recast published full life cycle GHG emission estimates, for each of the major animal-based categories in the US diet. Our calculations reveal that the environmental costs per consumed calorie of dairy, poultry, pork, and eggs are mutually comparable (to within a factor of 2), but strikingly lower than the impacts of beef. Beef production requires 28, 11, 5, and 6 times more land, irrigation water, GHG, and Nr, respectively, than the average of the other livestock categories. Preliminary analysis of three staple plant foods shows two- to sixfold lower land, GHG, and Nr requirements than those of the nonbeef animal-derived calories, whereas irrigation requirements are comparable. Our analysis is based on the best data currently available, but follow-up studies are necessary to improve parameter estimates and fill remaining knowledge gaps. Data imperfections notwithstanding, the key conclusion—that beef production demands about 1 order of magnitude more resources than alternative livestock categories—is robust under existing uncertainties. The study thus elucidates the multiple environmental benefits of potential, easy-to-implement dietary changes, and highlights the uniquely high resource demands of beef.
Designing for emotion (among other things)

Using computational approaches to emotion in design appears problematic for a range of technical, cultural and aesthetic reasons. After introducing some of the reasons as to why I am sceptical of such approaches, I describe a prototype we built that tried to address some of these problems, using sensor-based inferencing to comment upon domestic ‘well-being’ in ways that encouraged users to take authority over the emotional judgements offered by the system. Unfortunately, over two iterations we concluded that the prototype we built was a failure. I discuss the possible reasons for this and conclude that many of the problems we found are relevant more generally for designs based on computational approaches to emotion. As an alternative, I advocate a broader view of interaction design in which open-ended designs serve as resources for individual appropriation, and suggest that emotional experiences become one of several outcomes of engaging with them.
Experimental analysis of the toughness mechanism of rubber concrete

In this study, the Rubber Concrete (RC) specimen is manufactured by mixing the rubber particles with the size of 10 mesh, 40 mesh and 80 mesh instead of the refine aggregates with the volume fraction of 5% ~ 35% into the Plain Concrete (PC), and the complete stressstrain curves of RC are tested and compared to PC, and the results show that the mixing rubbers decrease the compressive strength, the flexural strength of the RC materials, but the RC has light weight and good toughness than ordinary concrete.
Energy and nutrient digestibilities in wheat dried distillers' grains with solubles fed to growing pigs

The aim of this study was to characterize the nutritional profile and to determine the digestibilities of nutrients in wheat-based dried distillers' grains with solubles (DDGS) fed to growing pigs. Six ileal cannulated barrows individually housed in metabolism crates were fed experimental diets which consisted of a basal wheat-based diet or the basal diet with wheat replaced by 400gkg −1 mixed wheat or winter wheat DDGS in a replicated 3 × 3 Latin square design. Ileal digesta and fecal samples were collected for determining apparent ileal (AID) and apparent total tract digestibilities (ATTD), respectively. The contents of proximate components and amino acids in DDGS were about three times higher than in wheat. The AID and ATTD of dry matter, nitrogen and energy were lower (P < 0.05) in DDGS compared with wheat. The DDGS samples had lower (P < 0.05) AID of amino acids compared with wheat; average values for lysine, threonine and isoleucine in DDGS were 43.8, 62.9 and 68.0%, respectively. The ileal and fecal digestible energy content in DDGS averaged 9.7 ± 1.18 and 13.5 ± 0.61 MJkg −1 , respectively. Respective values for wheat were 13.3 ± 0.52 and 14.6 ± 0.22 MJkg −1 and both were higher (P < 0.05) than in DDGS.  2005 Society of Chemical Industry
Refined Parameters of the Planet Orbiting HD 189733

We report on the BVRI multiband follow-up photometry of the transiting extrasolar planet HD 189733b. We revise the transit parameters and find a planetary radius of RP = 1.154 ± 0.033RJ and an inclination of iP = 85. °79 ± 0. °24. The new density (~1 g cm-3) is significantly higher than the former estimate (~0.75 g cm-3); this shows that from the current sample of nine transiting planets, only HD 209458 (and possibly OGLE-10b) have anomalously large radii and low densities. We note that due to the proximity of its parent star, HD 189733b currently has one of the most precise radius determinations among extrasolar planets. We calculate new ephemerides, P = 2.218573 ± 0.000020 days and T0 = 2453629.39420 ± 0.00024 (HJD), and estimate the timing offsets of the 11 distinct transits with respect to the predictions of a constant orbital period, which can be used to reveal the presence of additional planets in the system.
Distributed dynamic pricing for MIMO interfering multiuser systems: A unified approach

Wireless networks are composed of many users that usually have conflicting objectives and generate interference to each other. The system design is typically formulated as the optimization of the weighted sum of the users' utility functions. In an attempt to obtain distributed algorithms in the case this sum is nonconvex, researchers have proposed pricing mechanisms which however are based on heuristics and valid only for a restricted class of problems. In this paper we propose a general framework for the distributed optimization of the nonconvex sum-utility function. Our main contributions are: i) the derivation for the first time of a general dynamic pricing mechanism, ii) a framework that can be easily particularized to well-known applications, giving rise to very efficient practical algorithms that outperform existing methods; and iii) the solution to the currently open problem of social optimization for MIMO multiuser systems.
A note on zeros of $L$-series of elliptic curves

In this note we study an analogy between a positive definite quadratic form for elliptic curves over finite fields and a positive definite quadratic form for elliptic curves over the rational number field. A question is posed of which an affirmative answer would imply the analogue of the Riemann hypothesis for elliptic curves over the rational number field.
HIV, human papillomavirus, and cervical neoplasia and cancer in the era of highly active antiretroviral therapy

The objective of this study was to review the literature on the epidemiological association between human papillomavirus (HPV), HIV, and cervical neoplasia, and the impact of highly active antiretroviral therapy (HAART) on this association. MEDLINE was searched using the terms ‘human papillomavirus’, ‘HPV’, ‘HIV’, ‘cervix’, ‘neoplasm’, and ‘antiretroviral’ to identify articles published before December 2006. HIV-infection was strongly associated with a higher prevalence, incidence, and persistence of HPV infection and correlated with prevalence, incidence, persistence, and progression of squamous intraepithelial lesions. The association between HIV and invasive cervical carcinoma has been more difficult to establish, but is now fully recognized. HAART seems to have little, if any, beneficial effect on the natural history of intraepithelial lesions in HIV-positive women. Despite this fact, HAART, does increase the life expectancy of HIV-positive women. Therefore, it remains important to closely monitor HPV-related disease in women with HIV who are receiving HAART, particularly in regions of the world where cervical screening is not available routinely.
Changes in axial length and choroidal thickness after intraocular pressure reduction resulting from trabeculectomy

Purpose To evaluate changes in axial length and choroidal thickness after trabeculectomy. Patients and methods Fourteen patients under 80 years of age with glaucoma, were enrolled. The choroid was imaged using prototypical high-penetration optic coherence tomography (OCT) and the thickness was measured. Axial length, choroidal thickness, and intraocular pressure (IOP) were measured bilaterally at 3 pm 1 day before and 6 days after trabeculectomy. The choroidal thickness was measured at the fovea and four other locations (2 mm superior, temporal, inferior, and nasal to the center of the optic nerve head). Results The IOP and axial length significantly decreased in eyes that underwent trabeculectomy (P < 0.0001 for the IOP; P < 0.001 for axial length comparisons). The mean choroidal thicknesses significantly increased in eyes that underwent trabeculectomy compared to preoperatively (P < 0.0001 for the fovea; P < 0.01 for four locations around the optic disc). The mean magnitude of change in IOP was correlated positively with the mean magnitude of change in axial length, but not correlated with the mean magnitude of change in choroidal thickness at the fovea that underwent trabeculectomy. The sum of the axial length and subfoveal choroidal thickness in eyes decreased significantly postoperatively (P < 0.05). Conclusion The axial length shortened, the choroid thickened, and the sum of the axial length and subfoveal choroidal thickness decreased with IOP reduction early after trabeculectomy.
Statins for the prevention and treatment of infections: a systematic review and meta-analysis.

BACKGROUND Emerging epidemiological evidence suggests that statin use may reduce the risk of infections and infection-related complications. Our objective was to examine the association between statin use and the risk of infections and related outcomes. METHODS We searched several electronic databases from inception through December 2007 for randomized trials and cohort studies that examined the association between statin use and the risk or outcome of infections. Data on study characteristics, measurement of statin use, outcomes (adjusted for potential confounders), and quality assessment were extracted. RESULTS Sixteen cohorts were eligible and differed in representativeness, outcome assessment, and comparability of exposed (statin) and unexposed (nonstatin) groups. Nine cohorts addressed the role of statins in treating infections: bacteremia (n = 3), pneumonia (n = 3), sepsis (n = 2), and bacterial infection (n = 1). The pooled adjusted effect estimate was 0.55 (95% confidence interval, 0.36-0.83; I(2) = 76.5%) in favor of statins. Seven cohorts addressed infection prevention in patients with vascular diseases (n = 3), chronic kidney disease (n = 1), diabetes (n = 1), intensive care unit-acquired infections (n = 1), and in general practice (n = 1). The pooled effect estimate was 0.57 (95% confidence interval, 0.43-0.75; I(2) = 82%) in favor of statin use; there was some evidence of publication bias for this analysis (Egger test; P = .07). Meta-regression did not identify potential effect modifiers that explain the between-study heterogeneity. CONCLUSIONS Results for our meta-analysis suggest that statin use may be associated with a beneficial effect in treating and preventing different infections. Given the presence of heterogeneity and publication bias, there is a need for randomized trials to confirm the benefit of statin use in this context.
Agribusiness and the Efficiency of Agricultural Policy

A common finding in agricultural policy analysis is that agricultural policies fail to achieve their main objective of farm income support efficiently. Here it is argued that this might be the case because beside the explicit goal of supporting farm income government also pursues the implicit policy objective of supporting agribusiness. In particular, it is shown for the Austrian bread grains market that if we add agribusiness as a targeted group to government’s objective function the actually observed policy turns out to be quite efficient. This stimulates the question of the influence of the dimensions on the efficiency of a policy observed. *) Research associate, Department of Economics, Politics, and Law, Universität für Bodenkultur Wien, Tel. : ++43 1 47654 3653, FAX: ++43 1 47654 3692, Email: salhofer@edv1.boku. ac.at The author is grateful to David S. Bullock and participants of the 73 Annual Conference of the Western Economic Association International, in particular Evan W. Osborne, for helpful comments. The paper is a revised version of the winning entree of the 1997 Price Essay Competition of The Agricultural Economics Society.
Exploring new window manipulation techniques

Moving and resizing desktop windows are frequently performed but largely unexplored interaction tasks. The standard title bar and border dragging techniques used for window manipulation have not changed much over the years. We studied three new methods to move and resize windows. The new methods are based on proxy and goal-crossing techniques to eliminate the need of long cursor movements and acquiring narrow window borders. Instead, moving and resizing actions are performed by manipulating proxy objects close to the cursor and by sweeping cursor motions across window borders. We compared these techniques with the standard techniques. The results indicate that further investigations and redesigns of window manipulation techniques are worthwhile: all new techniques were faster than the standard techniques, with task completion times improving more than 50% in some cases. Also, the new resizing techniques were found to be less error-prone than the traditional click-and-drag method.
Social Responsibility in Transition of Stakeholders: From the School to the University

Abstract This chapter guides the reader to an understanding of social responsibility in educational settings, namely on school/university social responsibility (USR). The phenomenon of social responsibility in these settings is nuanced when encountering stakeholders, either external or internal. This chapter conceptualizes school/USR and describes related stakeholders and their management strategies. In addition to this, the chapter discusses eight transition lines of stakeholders developed on the expectations of stakeholders, the degree and the format of engagement and impacts on society and institutions: pupil–student; teachers-academics; parents; alumni; future employers; business sector; funding providers; and society at large. It concludes that a managerial pattern while implementing social responsibility by involving stakeholders differs by educational setting. This is to say that school social responsibility is rather carried out through process, whereas USR concerns both process and outputs. This distinction results in introducing the definition of school/USR as a commitment toward performance based on ethical and other conventional principles that are respectively substantiated in the mission, values and related activities in the interplay with all possible stakeholders in order to create social value foremost.