Miracle-dz/UniFAR-FTUs huggingface dataset:
LATITUDE VARIATIONS OF 7 MEV AND > 300 MEV COSMIC RAY ELECTRON FLUXES IN THE HELIOSPHERE : ULYSSES COSPIN/KET RESULTS AND IMPLICATIONS

The 160◦ latitude scan performed in less than one year between summer 1994 and summer 1995 by Ulysses allowed us to obtain unique data about the latitudinal dependence of the cosmic ray fluxes. We present in this paper results on the electron component derived from the COSPIN/KET instrument onboard Ulysses, both at MeV and GeV energies. The variations of the 1 to 7 GV electron fluxes do not show any feature which could be attributed to a latitude dependence. This observation deviates from the variations of the proton fluxes of similar rigidities. The electron/proton ratio is shown to depend unambiguously on latitude during the fast latitude scan of Ulysses. This latitudinal dependence can in fact be traced back in our data to at least mid 1993 when Ulysses left the streamer belt region. The time profiles of high energy electrons and protons are also compared with the predictions of a time dependent modulation model. It is found that our data can be reasonably well accounted for by assuming time-dependent increasing drift effects, asymmetric perpendicular diffusion and a rigidity (P ) dependence for the parallel mean free path derived by Bieber et al. (1994), i.e. ∝ P 0.3 between 0.9 and 2.5 GV. Regarding the ∼ 7 MeV electrons, we do not see any flux excess at the poles. This is in contradiction with the claim made by Simnett et al. (1995) of an entry of MeV galactic electrons over the poles. The flux excess they claim to have detected is inconsistent with our electron data by 30 to 60 standard deviations, depending on the spectral shape. We argue that this inconsistency may be attributed to a proton induced background in the Simnett et al. data. The KET data imply a conservative upper limit of 3.2 elec/m2.s. sr.MeV for the galactic electron flux at this energy.
Better Living Through Chemistry: Evolving GasNets for Robot Control

This paper introduces a new type of artificial neural network (GasNets) and shows that it is possible to use evolutionary computing techniques to find robot controllers based on them. The controllers are built from networks inspired by the modulatory effects of freely diffusing gases, especially nitric oxide, in real neuronal networks. Evolutionary robotics techniques were used to develop control networks and visual morphologies to enable a robot to achieve a target discrimination task under very noisy lighting conditions. A series of evolutionary runs with and without the gas modulation active demonstrated that networks incorporating modulation by diffusing gases evolved to produce successful controllers considerably faster than networks without this mechanism. GasNets also consistently achieved evolutionary success in far fewer evaluations than were needed when using more conventional connectionist style networks.
Treatment of intracerebellar haemorrhage: Poor outcome and high long-term mortality

Background: Intracerebellar haemorrhage constitutes around 10% of all spontaneous, non-aneurysmal intracerebral haemorrhages (ICHs) and often carries a grim prognosis. In symptomatic patients, surgical evacuation is usually regarded the standard treatment. Our objective was to compare the in-hospital mortality and functional outcome at hospital discharge in either medically or surgically treated patients, and the impact of either treatment on long-term mortality after a cerebellar ICH. Methods: An observational, retrospective, single-centre consecutive series of 114 patients with cerebellar ICH. We assessed the effect of different demographic factors on functional outcome and in-hospital mortality using logistic regression. We also divided the patients in medical and surgical treatment groups based on how they had been treated and compared the clinical and radiological parameters, in-hospital, and long-term mortality in the different groups. Results: In our series, 38 patients (33.3%) underwent haematoma evacuation and 76 (66.7%) received medical treatment. Glasgow coma scale <8, blocked quadrigeminal cistern, and severe hydrocephalus were associated with in-hospital death or poor functional outcome at discharge (modified Rankin scale 4-6). Surgically treated patients were younger, had larger haematomas both in volume and diameter, were in a worse clinical condition, and suffered more from hydrocephalus and brainstem compression. There were no statistically significant differences in in-hospital or long-term mortality. However, the surgically treated patients remained in a poor clinical condition. Conclusions: Surgical treatment of cerebellar ICH can be life-saving but often leads to a poor functional outcome. New studies are needed on long-term functional outcome after a cerebellar ICH.
Perihematomal Edema in Primary Intracerebral Hemorrhage Is Plasma Derived

Background and Purpose— The mechanisms of perihematomal injury in primary intracerebral hemorrhage (ICH) are incompletely understood. An MRI study was designed to elucidate the nature of edema and blood flow changes after ICH. Methods— Perihematomal blood flow and edema were studied prospectively with perfusion-weighted MRI (PWI) and diffusion-weighted MRI in 21 ICH patients. MRI and computed tomography (CT) images were coregistered to ensure perfusion and diffusion changes were outside of the hematoma. Edema volumes were measured on T2-weighted images. Apparent diffusion coefficient (ADC) values of the edematous regions were calculated. Results— Mean patient age was 64.2 years (45 to 89), and median National Institutes of Health stroke scale score was 12 (3 to 24). Median time to MRI was 21 hours (4.5 to 110). Average hematoma volume on CT was 26.1 (4 to 84) mL. PWI demonstrated perihematomal relative mean transit time (rMTT) was significantly correlated with hematoma volume (r =0.60; P =0.004) but not edema volume. Perihematomal oligemia (rMTT >2 s) was present in patients with hematoma volumes of >15 mL (average rMTT 4.6±2.0 s). Perihematomal edema was present in all patients. ADC values within this region (1178±213×10−6 mm2 /s) were increased 29% relative to contralateral homologous regions. Increases in perihematomal ADC predicted edema volume (r =0.54; P =0.012) and this was confirmed with multivariate analysis. Conclusions— Acute perihematomal oligemia occurs in acute ICH but is not associated with MRI markers of ischemia and is unrelated to edema formation. Increased rates of water diffusion in the perihematomal region independently predict edema volume, suggesting the latter is plasma derived.
The Effect of Media on Citizens' Fear of Crime in Turkey.

This study was conducted on-site in Istanbul, Turkey, to determine the effects that mass media has on citizens' perceptions about fear of crime, in particular, and fear, in general. Specifically, the study was designed to (1) determine the tendency of citizens' media consumption, (2) determine the level of fear of crime among Turkish citizens, (3) establish the effect of media on citizens' fear of crime, and (4) determine if gender, age, educational level, neighborhood, and monthly income have an independent effect on fear of crime. To achieve this purpose, after administering a survey in Istanbul, the researcher collected appropriate data and then utilized regression analysis to examine the relationship between media variables and fear of crime. A survey consisting of three parts was administered to 545 Turkish citizens over the age of 18 who currently reside in Istanbul, Turkey. In Part I of the survey, respondents were asked to identify their trends in relation to media consumption, and in Part II respondents were asked to report their feelings about fear of crime. Finally, Part III consisted of socio-demographic characteristics including gender, age, marital status, level of education, and income. The media variables used for this study were, general TV viewing, watching crime drama, watching TV news, listening to radio news, reading newspaper news, and reading Internet news. Regarding the independent effects of socio-demographic variables on fear of crime, only gender was found to be significantly related thereby supporting the research hypothesis. From six media variables, only watching crime drama show and reading Internet news found to be related with individuals' fear of crime; however, this relation disappeared after controlling with socio-demographic variables. In addition, no cultivation effect could be found among the sub-groups of sample.
A probable planetary companion to HD 39091 from the Anglo-Australian Planet Search

We report the detection of a extrasolar planet candidate orbiting the G1 V star HD 39091. The orbital period is 2083 d and the eccentricity is 0.62. With a minimum (M sin i) mass of 10.3 MJUP this object falls near the high mass end of the observed planet mass function, and may plausibly be a brown dwarf. Other characteristics of this system, including orbital eccentricity and metallicity, are typical of the well populated class of radial velocity planets in eccentric orbits around metal-rich stars.
Inhaled lead affects lung pathology and inflammation in sensitized and control guinea pigs

The association between lead exposure and respiratory diseases including asthma is controversial. Some studies indicate that exposure to environmental lead pollution may cause asthma; however, there is not sufficient data in this regard. The effect of lead on lung pathological findings and serum inflammatory mediators in sensitized and non‐sensitized guinea pigs exposed to inhaled lead was examined. Eleven animal groups including control, sensitized, three groups of non sensitized animals, three groups during sensitization, and three groups after sensitization exposed to aerosol of three lead concentrations (n = 6 for each group) were studied. Serum inflammatory mediators levels and lung pathological changes were evaluated. All pathological changes and serum ET‐1, EPO, NO levels were significantly higher in the sensitized and non sensitized animals exposed to lead than control group (p < 0.05 to p < 0.001). There was no significant difference between non sensitized groups exposed to high lead concentration and sensitized group. Serum inflammatory mediators levels and pathological findings in sensitized groups exposed to lead both during and after sensitization were significantly higher than sensitized non exposed group (p < 0.05 to p < 0.001). The data of exposed animals to high lead concentration were significantly higher than those of medium and low concentrations; those of medium concentration were also higher than low concentration (p < 0.05 to p < 0.001). In summary, the present study indicates that exposure to inhaled lead is able to induce respiratory changes similar to asthma. In addition, the results indicated that exposure to environmental lead is able to aggravate asthma severity both during development of asthma or after its manifestation. © 2014 Wiley Periodicals, Inc. Environ Toxicol 31: 452–460, 2016.
Emergence and Spread of Epidemic Multidrug-Resistant Pseudomonas aeruginosa

Abstract Pseudomonas aeruginosa (P. aeruginosa) is one of the most common nosocomial pathogens worldwide. Although the emergence of multidrug-resistant (MDR) P. aeruginosa is a critical problem in medical practice, the key features involved in the emergence and spread of MDR P. aeruginosa remain unknown. This study utilized whole genome sequence (WGS) analyses to define the population structure of 185 P. aeruginosa clinical isolates from several countries. Of these 185 isolates, 136 were categorized into sequence type (ST) 235, one of the most common types worldwide. Phylogenetic analysis showed that these isolates fell within seven subclades. Each subclade harbors characteristic drug resistance genes and a characteristic genetic background confined to a geographic location, suggesting that clonal expansion following antibiotic exposure is the driving force in generating the population structure of MDR P. aeruginosa. WGS analyses also showed that the substitution rate was markedly higher in ST235 MDR P. aeruginosa than in other strains. Notably, almost all ST235 isolates harbor the specific type IV secretion system and very few or none harbor the CRISPR/CAS system. These findings may help explain the mechanism underlying the emergence and spread of ST235 P. aeruginosa as the predominant MDR lineage.
The Effects of Cognitive-Behavioral Motivation for Health Improvement on Anthropometric Measurements in High Risk Individuals

Abstract : Unhealthy lifestyles cost businesses, governmental organizations, and the United States military billions of dollars every year. To fight this rising cost as well as potentially save lives this study sought to understand if a cognitive-behavioral motivation treatment could positively affect the cognitive variables (attitude, self-efficacy, and locus of control) that induce long term behavior change. Anthropometric measurements, specifically body mass index, abdominal circumference, and abdominal height, were used to determine if long term behavior change resulted from the treatment. The Theory of Planned Behavior was the basis of this thesis? model, while the Valence, Instrumentality, and Expectancy (VIE) theory was the foundation for the cognitive-behavioral motivation treatment. Structural Equation Modeling (SEM) tested the theory based model and found two results: a cognitive-behavioral motivation treatment can positively affect cognitive changes that improve behavior and health and, a causal or mediation relationship among the cognitive variables of locus of control and self-efficacy was found instead of the predicted parallel relationship. Effective implementation of an intervention like the one used in this study could lower the United States Air Force? s health care bill by as much as $40 million, improve employee efficiency and mission capability, enable longer healthier lives, and prevent premature death.
Effect of digital frequency compression (DFC) on speech recognition in candidates for combined electric and acoustic stimulation (EAS).

PURPOSE To compare the effects of conventional amplification (CA) and digital frequency compression (DFC) amplification on the speech recognition abilities of candidates for a partial-insertion cochlear implant, that is, candidates for combined electric and acoustic stimulation (EAS). METHOD The participants were 6 patients whose audiometric thresholds at 500 Hz and below were <or=60 dB HL and whose thresholds at 2000 Hz and above were >or=80 dB HL. Six tests of speech understanding were administered with CA and DFC. The Abbreviated Profile of Hearing Aid Benefit (APHAB) was also administered following use of CA and DFC. RESULTS Group mean scores were not statistically different in the CA and DFC conditions. However, 2 patients received substantial benefit in DFC conditions. APHAB scores suggested increased ease of communication, but also increased aversive sound quality. CONCLUSION Results suggest that a relatively small proportion of individuals who meet EAS candidacy will receive substantial benefit from a DFC hearing aid and that a larger proportion will receive at least a small benefit when speech is presented against a background of noise. This benefit, however, comes at a cost-aversive sound quality.
Opening the climate envelope reveals no macroscale associations with climate in European birds

Predicting how species distributions might shift as global climate changes is fundamental to the successful adaptation of conservation policy. An increasing number of studies have responded to this challenge by using climate envelopes, modeling the association between climate variables and species distributions. However, it is difficult to quantify how well species actually match climate. Here, we use null models to show that species–climate associations found by climate envelope methods are no better than chance for 68 of 100 European bird species. In line with predictions, we demonstrate that the species with distribution limits determined by climate have more northerly ranges. We conclude that scientific studies and climate change adaptation policies based on the indiscriminate use of climate envelope methods irrespective of species sensitivity to climate may be misleading and in need of revision.
International Conference on Information Systems ( ICIS ) 2010 IT CHALLENGES IN M & A TRANSACTIONS – THE IT CARVE-OUT VIEW ON DIVESTMENTS

Carve-outs belong to the most disruptive events companies – especially IT departments – are subject to. Yet the impact of these events on the IT alignment of the involved business units is largely unknown. This paper utilizes an alignment model to analyze specific IT-related challenges of divesting a strategic business unit (SBU). Hereby it focuses on the functional alignment between business strategy and IT at SBU level as well as on the organizational alignment between corporate and SBU. Based on five in-depth case studies of carve-outs taken place between 2004 and 2008, IT related challenges could be identified due to interdependent SBU information systems, a lack of IT governance, changing strategic scopes and the inability to preserve competencies. Dynamic capabilities were discovered as possible determinants for carve-out success. Carve-out management teams can utilize the analytical framework to make a SBU carveout ready, to guide IT due diligence and to prioritize IT issues.
Towards Representation Learning with Tractable Probabilistic Models

Probabilistic models learned as density estimators can be exploited in representation learning beside being toolboxes used to answer inference queries only. However, how to extract useful representations highly depends on the particular model involved. We argue that tractable inference, i.e. inference that can be computed in polynomial time, can enable general schemes to extract features from black box models. We plan to investigate how Tractable Probabilistic Models (TPMs) can be exploited to generate embeddings by random query evaluations. We devise two experimental designs to assess and compare different TPMs as feature extractors in an unsupervised representation learning framework. We show some experimental results on standard image datasets by applying such a method to Sum-Product Networks and Mixture of Trees as tractable models generating embeddings.
Beyond Revenge: The Evolution of the Forgiveness Instinct

Acknowledgments. Introduction: Three Simple Truths About Revenge and Forgiveness. 1 Putting Vengeance and Forgiveness Back into Human Nature. 2 Revenge Is a Problem: Counting the Costs. 3 Revenge Is a Solution: Three Evolutionary Hypotheses. 4 The Retribution Solution: The Evidence for Adaptation. 5 Family, Friendship, and the Functions of Forgiveness. 6 The Forgiveness Instinct. 7 The Forgiving Brain. 8 "To Promote and to Maintain Friendly Relations": Making Forgiveness Happen. 9 From Neurons to Nations. 10 Divine Forgiveness and Righteous Revenge. 11 Homo ignoscens. Notes. Bibliography. The Author. Index.
Molecular characteristics of class 1 and class 2 integrons and their relationships to antibiotic resistance in clinical isolates of Shigella sonnei and Shigella flexneri.

OBJECTIVES To analyse the gene cassettes and determine the roles of class 1 and class 2 integrons in antibiotic-resistant strains of Shigella sonnei (n=31) and Shigella flexneri (n=33). METHODS Various molecular techniques, including PCR and Southern-blotting analysis, were used to analyse various markers of class 1 and class 2 integrons in these 64 S. sonnei and S. flexneri isolates collected in Hangzhou, China. The gene cassette arrays in integrons were identified by DNA sequencing and/or restriction fragment length polymorphism. Two genomic DNA fragments, one containing intI1 from a S. flexneri isolate that contains intI1 but lacks 3'-conserved region and another containing intI2 from a S. sonnei isolate, were cloned into pUC19 vectors and sequenced. The links between integron gene cassette arrays and antibiotic resistance were analysed. RESULTS Class 2 integrons were present in 80.6% (25/31) of the S. sonnei isolates and 87.9% (29/33) of the S. flexneri isolates. All of these integron 2-positive isolates contained constant gene cassette arrays of dfrA1+sat1+aadA1 which confer resistance to trimethoprim and streptomycin. It was demonstrated that the class 2 integron was located in the Tn7 region inside the attTn7 locus downstream of glmS in Shigella. Class 1 integrons were found in 9.4% (6/64) of Shigella spp. isolates. An atypical class 1 integron without a 3'-conserved segment on the Shigella chromosome, termed Shigella atypical class 1 integron (SAI), was present in 84.9% (28/33) of S. flexneri isolates. The SAI contained two gene cassettes, bla(OXA30) and aadA1; however, the SAI conferred resistance to ampicillin, but not to streptomycin, in Escherichia coli host. The bla(OXA30) and aadA1 cassettes of the SAI seemed to be always coordinately excised or integrated. CONCLUSIONS Multiple and complex mechanisms involving mobile genetic elements in class 1 and class 2 integrons and antibiotic resistance have been developed in the evolution of Shigella strains.
Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome

The majority of microbial genomic diversity remains unexplored. This is largely due to our inability to culture most microorganisms in isolation, which is a prerequisite for traditional genome sequencing. Single-cell sequencing has allowed researchers to circumvent this limitation. DNA is amplified directly from a single cell using the whole-genome amplification technique of multiple displacement amplification (MDA). However, MDA from a single chromosome copy suffers from amplification bias and a large loss of specificity from even very small amounts of DNA contamination, which makes assembling a genome difficult and completely finishing a genome impossible except in extraordinary circumstances. Gel microdrop cultivation allows culturing of a diverse microbial community and provides hundreds to thousands of genetically identical cells as input for an MDA reaction. We demonstrate the utility of this approach by comparing sequencing results of gel microdroplets and single cells following MDA. Bias is reduced in the MDA reaction and genome sequencing, and assembly is greatly improved when using gel microdroplets. We acquired multiple near-complete genomes for two bacterial species from human oral and stool microbiome samples. A significant amount of genome diversity, including single nucleotide polymorphisms and genome recombination, is discovered. Gel microdroplets offer a powerful and high-throughput technology for assembling whole genomes from complex samples and for probing the pan-genome of naturally occurring populations.