Miracle-dz/UniFAR-FTUs huggingface dataset:
Study the effectiveness of cognitive-behavioral intervention on the quality of life, job satisfaction, and nurses' organizational performance

Background and aims: Quality of life is an important concept in how to play the role of nursing care. In addition, the performance and job satisfaction of nurses as components of the effective health systems to provide better services to clients are in a particular significance. The aim of this study was to investigate the effectiveness of cognitive-behavioral intervention on the quality of life, organizational performance, and job satisfaction of nurses. Methods: The current study is a quasi-experimental research with pre-test and post-test with control group. The first experimental group received cognitive-behavioral training and the second group without training is studied. Both groups response the pre-test and post-test at the same time. The population studied in this research study comprised nurses who were working in Tabriz hospitals in the second half 2016. The primary samples in this study were 205 nurses who were determined in convenience after the implementation of a pilot study. 40 nurses first with lower scores on tests were selected and divided into two experimental and control groups (each 20 people). Tools of the research were questionnaires of The World Health Organization Quality of Life, Paterson Organizational Performance, Berry Field and Ruth job satisfaction questionnaire and Content of the Sessions of Cognitive Therapy Group. Data were analyzed using SPSS software and multivariate covariance analysis test. Results: The results of the research showed that the education of cognitive-behavioral intervention on the variables of quality of life, job satisfaction and organizational performance nurses have a significant positive effect (P<0.05). Conclusion: Regarding the effectiveness of cognitive-behavioral intervention training, it is recommended interventional programs for nurses be used in order to improve quality of life and increase job satisfaction and their organizational performance.
Hodgkin lymphoma: clinicopathologic features in Benin City, Nigeria and update on its biology and classification.

OBJECTIVE To review the age incidence, common pathohistologic subtypes, and anatomical nodal sites of lymph nodes involvement for histology. MATERIALS AND METHODS A 25 (May 1985-June 2010) years retrospective study of all patients who had lymph node biopsy. SETTING Department of Pathology and Haematology, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS Of 821 lymph node biopsies encountered, 56 (6.8%) cases biopsied were for Hodgkin lymphoma (HL). There was a bimodal peak incidence of age interval of 11-15 years and 21-25 years and the relationship between the age and sex distribution was statistically significant (P = 0.03). The overall median age was 23 years with a mean age of 25.6 ± 2.0 (SEM). Pathological re-appraisal of these 56 cases in the study indicates that mixed cellularity HL constituting 36 cases (64.3%) was the predominant subtype. This was followed by lymphocyte depleted HL with a total of 11 cases (19.6%). The major site of lymph node involvement where biopsy was taken for histological diagnosis was the cervical group of lymph nodes constituting 78.6%. Staging classification of the disease indicates low frequency of early stage disease (I-II) with 19 cases (33.9%) and high frequency of late stage (III-IV) with 37 cases (66.1%). CONCLUSION Patients are predominantly males, children and young adults presenting with cervical lymphadenopathy at late stage of the disease, and a dominance of mixed cellularity and lymphocyte depleted histological subtypes were observed.
Poetic prosumption of animation, comic, game and novel in a post-socialist China: A case of a popular video-sharing social media Bilibili as heterotopia

Based on the case of Bilibili, a popular Chinese video-sharing social media with a core focus on animation, comic, game and novel, this article examines the transnational prosumption practices of Chinese urban youth who mostly belong to Generation Z. I conduct ethnographic research and in-depth interviews with animation, comic, game and novel fans to investigate the construction of heterotopia on Bilibili through their various practices of tactical prosumption. This article demonstrates that young animation, comic, game and novel fans prosume, socialise and express themselves in a tactical and poetic way within the heterotopia, a place of otherness. Various tactics are employed to challenge and counter control, social norms as well as consumerism. Starting with a critical engagement with Azuma’s pessimistic view on animation, comic, game and novel fan culture, the notion of ‘database animals’, I argue that a neglected, albeit nuanced, poetic and tactical prosumption process is evident on Chinese social media. Being the results of an interdisciplinary study, the findings will be helpful to scholars who are interested in contemporary Chinese studies with a focus on the animation industry, fandom, consumption and social media.
On the solution of a finite element approximation of a linear obstacle plate problem

In this paper the solution of a finite element approximation of a linear obstacle plate problem is investigated. A simple version of an interior point method and a block pivoting algorithm have been proposed for the solution of this problem. Special purpose implementations of these procedures are included and have been used in the solution of a set of test problems. The results of these experiences indicate that these procedures are quite efficient to deal with these instances and compare favourably with the path-following PATH and the active-set MINOS codes of the commercial GAMS collection.
Efficacy and harm of pharmacological prevention of acute mountain sickness: quantitative systematic review

Abstract Objective: To quantify efficacy and harm of pharmacological prevention of acute mountain sickness. Data sources: Systematic search (Medline, Embase, Cochrane Library, internet, bibliographies, authors) in any language, up to October 1999. Study selection: Randomised placebo controlled trials. Data extraction: Dichotomous data on efficacy and harm from 33 trials (523 subjects received 13 different interventions, 519 a placebo). Data synthesis: At above 4000 m the mean incidence of acute mountain sickness with placebo was 67% (range 25% to 100%); incidence depended on the rate of ascent, but not on the altitude or the mode of ascent. Across all ascent rates, dexamethasone 8–16 mg prevented acute mountain sickness (relative risk 2.50 (95% confidence interval 1.71 to 3.66); number needed to treat (NNT) 2.8 (2.0 to 4.6)), without evidence of dose responsiveness. Acetazolamide 750 mg was also efficacious (2.18 (1.52 to 3.15); NNT 2.9 (2.0 to 5.2)), but 500 mg was not. In two trials, adverse reaction (including depression) occurred after dexamethasone was stopped abruptly (4.45 (1.08 to 18); NNT 3.7 (2.5 to 6.9)). With acetazolamide, paraesthesia (4.02 (1.71 to 9.43); NNT 3.0 (2.0 to 6.0)) and polyuria (4.24 (1.92 to 9.37); NNT 3.6 (2.5 to 6.2)) were reported. Data were sparse on nifedipine, frusemide (furosemide), dihydroxyaluminium-sodium, spironolactone, phenytoin, codeine, phenformin, antidiuretic hormone, and ginkgo biloba. Conclusions: At above 4000 m, with a high ascent rate, fewer than three subjects need to be treated with prophylactic dexamethasone 8–16 mg or acetazolamide 750 mg for one subject not to experience acute mountain sickness who would have done so had they all received a placebo. Acetazolamide 500 mg does not work.
Fruit removal increases root-zone respiration in cucumber

Background and Aims Many attempts have been made to avoid the commonly observed fluctuations in fruit initiation and fruit growth in crop plants, particularly in cucumber (Cucumis sativus). Weak sinks of the fruit have been assumed to result in low sink/source ratios for carbohydrates, which may inhibit photosynthesis. This study focuses on the effects of low sink–source ratios on photosynthesis and respiration, and in particular root-zone respiration. Methods Mature fruit-bearing cucumber plants were grown in an aerated nutrient solution. The root containers were designed as open chambers to allow measurement of CO2 gas exchange in the root zone. A similar arrangement in a gas-exchange cuvette enabled simultaneous measurements of CO2 exchange in the shoot and root zones. Key Results Reducing the sinks for carbohydrates by removing all fruit from the plants always resulted in a doubling of CO2 exchange in the root zone within a few hours. However, respiration of the shoot remained unaffected and photosynthesis was only marginally reduced, if at all. Conclusions The results suggest that the increased level of CO2 gas exchange in the root zone after removing the carbon sinks in the shoot is due primarily to the exudation of organic compounds by the roots and their decomposition by micro-organisms. This hypothesis must be tested in further experiments, but if proved correct it would make sense to include carbon leakage by root exudation in cucumber production models. In contrast, inhibition of photosynthesis was measurable only at zero fruit load, a situation that does not occur in cucumber production systems, and models that estimate production can therefore ignore (end-product) inhibition of photosynthesis.
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major

Previous studies with inhibitors of inducible nitric oxide synthase (iNOS) suggested that high-output production of nitric oxide (NO) is an important antimicrobial effector pathway in vitro and in vivo. Here, we investigated the tissue expression of iNOS in mice after infection with Leishmania major. Immunohistochemical staining with an iNOS-specific antiserum revealed that in the cutaneous lesion and draining lymph nodes (LN) of clinically resistant mice (C57BL/6), iNOS protein is found earlier during infection and in significantly higher amounts than in the nonhealing BALB/c strain. Similar differences were seen on the mRNA level as quantitated by competitive polymerase chain reaction. Anti-CD4 treatment of BALB/c mice not only induced resistance to disease, but also restored the expression of iNOS in the tissue. In situ, few or no parasites were found in those regions of the skin lesion and the draining LN which were highly positive for iNOS. By double labeling experiments, macrophages were identified as iNOS expressing cells in vivo. In the lesions of BALB/c mice, cells staining positively for transforming growth factor beta (TGF-beta), a potent inhibitor of iNOS in vitro, were strikingly more prominent than in C57BL/6, whereas no such difference was found for interleukin 4 or interferon gamma (IFN-gamma). In vitro, production of NO was approximately threefold higher in C57BL/6 than in BALB/c macrophages after stimulation with IFN-gamma. We conclude that the pronounced expression of iNOS in resistant mice is an important mechanism for the elimination of Leishmania in vivo. The relative lack of iNOS in susceptible mice might be a consequence of macrophage deactivation by TGF-beta and reduced responsiveness to IFN-gamma.
Comparative Effectiveness of Mixed Reality-Based Virtual Environments in Collaborative Design

This paper presents two mixed-reality (MR) environments that provide alternative mediums that allow groups of people to share the same work and communication space in face-to-face and remote manners. Two experiments were executed to test the capabilities of the two MR systems in realistic environment and collaborative tasks against prevalent methods. Results indicated that the two MR systems significantly reduced the performance time for the collaborative design error detection task. Results also indicated less mental effort for the MR systems, suggesting that some of the mental interpretation for the error detection task is offloaded to the MR systems.
OUTBURSTS OF IRRADIATED ACCRETION DISCS

I thank Hans Ritter, John Cannizzo and Henk Spruit for very helpful discussions, Graham Wynn for help with curve– fitting, and the U.K. Particle Physics and Astronomy Research Council for a Senior Fellowship. Theoretical astrophysics research at Leicester is supported by a PPARC Rolling Grant.
On the hydrological cycle under paleoclimaticconditions as derived from AGCM simulationsGerrit

The atmospheric hydrological cycle is compared for diierent time slices of the late Quaternary. Simulations have been conducted with an atmospheric circulation model at T42 resolution, and we have performed a global evaluation of the atmospheric water vapor transport. The water export from the Atlantic catchment area, important for driving the large-scale thermohaline ocean circulation, is analyzed in detail. For the Last Glacial Maximum (LGM), we examine the model's sensitivity with respect to tropical cooling relative to the CLIMAP reconstruction which is motivated by recent data. We nd that the LGM experiment with tropical cooling is in better agreement with proxy data available. Our experiments indicate that the water vapor transport is strongly aaected by three mechanisms: continental drying, eddy moisture transport, and changes in the tropical circulation. Except for the continental drying and the blocking eeect of the Laurentide ice sheet, the hydrological cycle is substancially diierent for both LGM experiments. We nd that the hydrological system is rather sensitive to tropical temperature change which is important to understand paleoclimate and future climate changes.
Identifying scalar behavior in CUDA kernels

We propose a compiler analysis pass for programs expressed in the Single Program, Multiple Data (SPMD) programming model. It identifies statically several kinds of regular patterns that can occur between adjacent threads, including common computations, memory accesses at consecutive locations or at the same location and uniform control flow. This knowledge can be exploited by SPMD compilers targeting SIMD architectures. We present a compiler pass developed within the Ocelot framework that performs this analysis on NVIDIA CUDA programs at the PTX intermediate language level. Results are compared with optima obtained by simulation of several sets of CUDA benchmarks.
The IMMUTANS Variegation Locus of Arabidopsis Defines a Mitochondrial Alternative Oxidase Homolog That Functions during Early Chloroplast Biogenesis

Nuclear gene–induced variegation mutants provide a powerful system to dissect interactions between the genetic systems of the nucleus–cytoplasm, the chloroplast, and the mitochondrion. The immutans (im) variegation mutation of Arabidopsis is nuclear and recessive and results in the production of green- and white-sectored leaves. The green sectors contain cells with normal chloroplasts, whereas the white sectors are heteroplastidic and contain cells with abnormal, pigment-deficient plastids as well as some normal chloroplasts. White sector formation can be promoted by enhanced light intensities, but sectoring becomes irreversible early in leaf development. The white sectors accumulate the carotenoid precursor phytoene. We have positionally cloned IM and found that the gene encodes a 40.5-kD protein with sequence motifs characteristic of alternative oxidase, a mitochondrial protein that functions as a terminal oxidase in the respiratory chains of all plants. However, phylogenetic analyses revealed that the IM protein is only distantly related to these other alternative oxidases, suggesting that IM is a novel member of this protein class. We sequenced three alleles of im, and all are predicted to be null. Our data suggest a model of variegation in which the IM protein functions early in chloroplast biogenesis as a component of a redox chain responsible for phytoene desaturation but that a redundant electron transfer function is capable of compensating for IM activity in some plastids and cells.
Naturopathic Cancer Treatment: Associated with Increased Quality of Life

The purpose of this investigation was to assess the effects of an individualized naturopathic treatment plan on the overall quality of life (QOL) of cancer patients as pertaining to fatigue, pain and overall mood. Twenty-two male (n = 10) and female (12) cancer patients ranging in age from 32 to 82 years-of-age volunteered from a cancer rehabilitation center in Kalispell, MT. Subjects were given the option to utilize a naturopathic treatment option via their physician. Each subject completed a FACT-G questionnaire at the beginning and the end of the study. This short survey asked the subjects a range of questions pertaining to subscales including personal well-being (PWB), social well-being (SWB), emotional well-being (EWB), functional well-being (FWB) and total score. A Dependent t-test was used to examine whether difference (s) existed within the cancer patients from pre to post survey scores (P < 0.05). Significant differences were found in PWB, SWB, EWB and total score (P < 0.05). In all categories, the QOL subscales favorably increased from the pre to post values. These findings demonstrate that naturopathic rehabilitation can be a positive alternative treatment for cancer patients undergoing therapy.
Do offenders have distinct offending patterns before they join adult gang criminal groups? Analyses of crime specialization and escalation in offence seriousness

Researchers have put serious efforts into identifying youth at high risk of joining gangs. Their main focus has been on street gangs, whereas risk factors for joining adult gang criminal groups have received less attention. This study examines crime specialization and crime seriousness prior to gang initiation among 564 adult gang members, 800 outlaw bikers and matched comparison groups of offenders (up to three offenders convicted of the same number of offences) who stayed out of such gangs. The data stem from Statistics Denmark and the Police Intelligence Database. The study findings demonstrate that the gang members and the outlaw bikers commit more serious offences than their non-gang counterparts, but the study also provides evidence that it is difficult – most likely impossible – to identify upcoming members of gangs by paying attention to crime patterns only.
Memory centric thread synchronization on platform FPGAs

Concurrent programs are difficult to write, reason about, re-use, and maintain. In particular, for system-level descriptions that use a shared memory abstraction for thread or process synchronization, the current practice involves manual scheduling of processes, introduction of guard conditions, and clocking tricks, to enforce memory dependencies. This process is tedious, time consuming, and error-prone. At the same time, the need for a concurrent programming model is becoming ever essential to bridge the productivity gap that is widening with every manufacturing process generation. In this paper, we present two novel techniques to automatically enforce memory dependencies in platform FPGAs using on-chip memories, starting from a system-level description. Both the techniques utilize static analysis to generate circuits for enforcing these dependencies. This paper investigates these two techniques for their generality, overhead in implementation, and usefulness or otherwise for different application requirements
Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells.

AIMS Sphingosine-1-phosphate (S1P), a key regulator of vascular homeostasis and angiogenesis, promotes endothelial cell migration via stimulation of phosphoinositide 3-kinase (PI3K). The aim of this study was to identify the role of PI3Kbeta and gamma isoforms and their downstream effector pathways in mediating endothelial cell migration induced by S1P. METHODS AND RESULTS Experiments were performed in human umbilical vein endothelial cells (HUVEC) and murine lung endothelial cells (MLEC). A combination of specific inhibitors, RNA interference, and PI3Kgamma(-/-) mice were used to investigate the role of PI3Kbeta and gamma isoforms in endothelial cell migration. Both PI3Kbeta and gamma isoforms are required for full migration induced by S1P, with Rac1 being a major mediator downstream of both isoforms. In addition, PI3Kbeta but not PI3Kgamma mediates migration via Akt but independent of Rac1 and endothelial NO synthase (eNOS). Further, a S1P-mediated activation of extracellular signal-regulated kinases (Erk) 1/2 contributes to the chemotactic response independent of PI3Kbeta or PI3Kgamma. CONCLUSIONS Our data demonstrate that both PI3Kbeta and PI3Kgamma isoforms are required for S1P-induced endothelial cell migration through activation of Rac1. In addition, PI3Kbeta initiates an Akt-sensitive chemotactic response which is independent of Rac1 and eNOS. Thus, PI3Kbeta and PI3Kgamma have both overlapping and distinct roles in regulating endothelial cell migration, which may underlie S1P-triggered angiogenic differentiation.
Efficient Lipschitz Extensions for High-Dimensional Graph Statistics and Node Private Degree Distributions

Lipschitz extensions were recently proposed as a tool for designing node differentially private algorithms. However, efficiently computable Lipschitz extensions were known only for 1-dimensional functions (that is, functions that output a single real value). In this paper, we study efficiently computable Lipschitz extensions for multi-dimensional (that is, vector-valued) functions on graphs. We show that, unlike for 1-dimensional functions, Lipschitz extensions of higher-dimensional functions on graphs do not always exist, even with a non-unit stretch. We design Lipschitz extensions with small stretch for the sorted degree list and for the degree distribution of a graph. Crucially, our extensions are efficiently computable. We also develop new tools for employing Lipschitz extensions in the design of differentially private algorithms. Specifically, we generalize the exponential mechanism, a widely used tool in data privacy. The exponential mechanism is given a collection of score functions that map datasets to real values. It attempts to return the name of the function with nearly minimum value on the data set. Our generalized exponential mechanism provides better accuracy when the sensitivity of an optimal score function is much smaller than the maximum sensitivity of score functions. We use our Lipschitz extension and the generalized exponential mechanism to design a node-differentially private algorithm for releasing an approximation to the degree distribution of a graph. Our algorithm is much more accurate than algorithms from previous work.