Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing an Enterprise Business Intelligence Capability: The Norfolk Southern Journey

Although many IT and business managers today may be lured into business intelligence (BI) investments by the promise of predictive analytics and emerging BI trends, creating an enterprise-wide BI capability is a journey that takes time. This article describes Norfolk Southern Railway’s BI journey, which began in the early 1990s with departmental reporting, evolved into data warehousing and analytic applications, and has resulted in a company that today uses BI to support corporate strategy. We describe how BI at Norfolk Southern evolved over several decades, with the company developing strong BI foundations and an effective enterprise-wide BI capability. We also identify the practices that kept the BI journey “on track. ” These practices can be used by other IT and business leaders as they plan and develop BI capabilities in their own organizations.
Muslim Youth in Canadian Schools: Education and the Politics of Religious Identity

This article provides an ethnographic analysis of the schooling experiences of Muslim youth in Canada who are committed to maintaining an Islamic lifestyle despite the pressures of conformity to the dominant culture. Little attention has been paid to how religious identity intersects with other forms of social difference, such as race and gender in the schooling experiences of minoritized youth. Using a case study often Muslim students and parents, this article demonstrates how Muslim students were able to negotiate and maintain their religious identities within secular public schools. The participants' narratives address the challenges of peer pressure, racism, and Islamophobia. Their stories reveal how Muslim students are located at the nexus of social difference based on their race, gender, and religious identity. The discussion further explores the dynamics through which these youth were able to negotiate the continuity of their Islamic identity and practices within schools despite the challenges that they faced. Building upon existing theories of identity maintenance and construction, this research demonstrates how the interplay of the core factors of ambivalence, role performance, and interaction and isolation are implicated in the way Muslim students negotiate the politics of religious identity in their schooling experiences.
Long noncoding RNA PVT1 promotes cervical cancer progression through epigenetically silencing miR‐200b

Long noncoding RNA PVT1 has been reported to be dysregulated and play vital roles in a variety of cancers. However, the functions and molecular mechanisms of PVT1 in cervical cancer remain unclear. The objective of this study was to investigate the expression, clinical significance, biological roles, and underlying functional mechanisms of PVT1 in cervical cancer. Our results revealed that PVT1 is upregulated in cervical cancer tissues. Enhanced expression of PVT1 is associated with larger tumor size, advanced International Federation of Gynecology and Obstetrics stage, and poor prognosis of cervical cancer patients. Using gain‐of‐function and loss‐of‐function approaches, we demonstrated that overexpression of PVT1 promotes cervical cancer cells proliferation, cell cycle progression and migration, and depletion of PVT1 inhibits cervical cancer cell proliferation, cell cycle progression, and migration. Mechanistically, we verified that PVT1 binds to EZH2, recruits EZH2 to the miR‐200b promoter, increases histone H3K27 trimethylation level on the miR‐200b promoter, and inhibits miR‐200b expression. Furthermore, the effects of PVT1 on cervical cell proliferation and migration depend upon silencing of miR‐200b. Taken together, our findings confirmed that PVT1 functions as an oncogene in cervical cancer and indicated that PVT1 is not only an important prognostic marker, but also a potential therapy target for cervical cancer.
Involving children in reflective discussions about their perceived self-efficacy and learning experiences

Previous research indicates the importance of self-efficacy beliefs for young children's learning and achievement. However, the challenge has been to research young children's self-efficacy in authentic learning situations. Therefore, the aims of this study were to investigate young children's immediate experiences of confidence in specific classroom-learning situations and to explore the factors that support young children's self-efficacy. The participants (n = 24, children aged six to eight years) from four primary school classrooms were videotaped over the course of seven weeks. During recall discussions, the video clips from the videotaped classroom activities were used to stimulate children's memory regarding the confidence they experienced in specific learning situations. Three levels of confidence (high, moderate and low) were identified. The results showed that three interactive learning contexts (child-teacher-task, child-task and child-child-task) support the development of children's self-efficacy. The findings elucidate the factors influencing children's confidence and indicate it is essential to involve them in discussions about their learning experiences and self-efficacy beliefs. This paper adds to the literature on participatory approaches involving young children in aspects of the analysis and provides important information on how teachers can scaffold young children's confidence and promote self-efficacy in the classroom.
Dextrose 5% in water: fluid medium for maintaining electrical stimulation of peripheral nerves during stimulating catheter placement

It is well documented that a higher electrical current is required to elicit a motor response following a normal saline (NS) injection during the placement of stimulating catheters for peripheral nerve block. We present three cases of continuous brachial plexus catheter placement in which Dextrose 5% in water (D5W) was used to dilate the perineural space instead of NS. Three brachial plexus blocks (two interscalene and one axillary) were performed in three different patients for pain relief. In each case, an insulated needle was advanced towards the brachial plexus. A corresponding motor response was elicited with a current less than 0.5 mA after needle repositioning. A stimulating catheter was advanced with ease after 3–5 ml of D5W was injected to dilate the perineural space. A corresponding motor response was maintained when the current applied to the stimulating catheter was less than 0.5 mA. Local anesthetic was then injected and the motor response immediately ceased. All blocks were successful and provided excellent pain relief with the continuous infusion of local anesthetics.
A Cross-Cultural Verification of a Social Control Theory

The most discussed social control theory of crime has been put forth by Travis Hirschi. In this paper we are interested in examining the relationship between the elements of the bond and self-reported delinquent behavior. In methodology, the paper is a replication of Hirschi's analysis on a random sample of French speaking adolescents of Montreal. We were able to replicate Hirschi's findings on commitment, belief, and involvement; but there were some differences concerning attachment. There seems to be a cultural difference in the importance of the attachment to school: it is much less significant in the French sample.
Explicit argumentation instruction to facilitate conceptual understanding and argumentation skills

Background: Argumentation is accepted by many science educators as a major component of science education. Many studies have investigated students’ conceptual understanding and their engagement in argumentative activities. However, studies conducted in the subject of chemistry are very rare. Purpose: The present study aimed to investigate the effects of argumentation-based chemistry lessons on pre-service science teachers’ understanding of reaction rate concepts, their quality of argumentation, and their consideration of specific reaction rate concepts in constructing an argument. Moreover, students’ perceptions of argumentation lessons were explored. Sample: There were 116 participants (21 male and 95 female), who were pre-service first-grade science teachers from a public university. The participants were recruited from the two intact classes of a General Chemistry II course, both of which were taught by the same instructor. Design and methods: In the present study, non-equivalent control group design was used as a part of quasi-experimental design. The experimental group was taught using explicit argumentation activities, and the control group was instructed using traditional instruction. The data were collected using a reaction rate concept test, a pre-service teachers’ survey, and the participants’ perceptions of the argumentation lessons questionnaire. For the data analysis, the Wilcoxon Signed Rank Test, the Mann–Whitney U-test and qualitative techniques were used. Results: The results of the study indicated that an argumentation-based intervention caused significantly better acquisition of scientific reaction rate-related concepts and positively impacted the structure and complexity of pre-service teachers’ argumentation. Moreover, the majority of the participants reported positive feelings toward argumentation activities. Conclusions: As students are encouraged to state and support their view in the chemistry classroom when studying reaction rate, it was observed that their understanding increased in terms of both the context and the quality of the argumentation that they produced. In light of the findings, it is suggested that argumentation activities should be developed to promote students’ science content knowledge and argumentation skills.
The interaction of socioeconomic position and type 2 diabetes mellitus family history: a cross-sectional analysis of the Lifelines Cohort and Biobank Study

Background Low socioeconomic position (SEP) and family history of type 2 diabetes mellitus (T2DM) contribute to increased T2DM risk, but it is unclear whether they exacerbate each other’s effect. This study examined whether SEP reinforces the association of T2DM family history with T2DM, and whether behavioural and clinical risk factors can explain this reinforcement. Methods We used cross-sectional data on 51 725 participants from Lifelines. SEP was measured as educational level and was self-reported, just as family history of T2DM. T2DM was diagnosed based on measured fasting plasma glucose and glycated haemoglobin, combined with self-reported disease and recorded medication use. We assessed interaction on the additive scale by calculating the relative excess risk due to interaction (RERI). Results ORs of T2DM were highest for males (4.37; 95% CI 3.47 to 5.51) and females (7.77; 5.71 to 10.56) with the combination of low SEP and a family history of T2DM. The RERIs of low SEP and a family history of T2DM were 0.64 (−0.33 to 1.62) for males and 3.07 (1.53 to 4.60) for females. Adjustment for behavioural and clinical risk factors attenuated associations and interactions, but risks remained increased. Conclusion Low SEP and family history of T2DM are associated with T2DM, but they also exacerbate each other’s impact in females but not in males. Behavioural and clinical risk factors partly explain these gender differences, as well as the associations underlying the interaction in females. The exacerbation by low SEP of T2DM risks in T2DM families deserves attention in prevention and community care.
Separating the ‘teaching’ from the ‘academic’: possible unintended consequences

Academics' development as teachers is traditionally considered independently from their development in other aspects of their work, or from their development as an academic holistically. Through the analysis of two previous phenomenographic studies of academics' experiences of: (1) their growth and development as an academic holistically; and (2) their growth and development as a university teacher in particular, this paper explores interrelationships between the experience of developing as an academic and developing as a teacher. This allows consideration of what may be lost by separating teaching and teaching development from other aspects of academic work and academic development.
Delineation of Streptococcus dysgalactiae, Its Subspecies, and Its Clinical and Phylogenetic Relationship to Streptococcus pyogenes

ABSTRACT The taxonomic status and structure of Streptococcus dysgalactiae have been the object of much confusion. Bacteria belonging to this species are usually referred to as Lancefield group C or group G streptococci in clinical settings in spite of the fact that these terms lack precision and prevent recognition of the exact clinical relevance of these bacteria. The purpose of this study was to develop an improved basis for delineation and identification of the individual species of the pyogenic group of streptococci in the clinical microbiology laboratory, with a special focus on S. dysgalactiae. We critically reexamined the genetic relationships of the species S. dysgalactiae, Streptococcus pyogenes, Streptococcus canis, and Streptococcus equi, which may share Lancefield group antigens, by phylogenetic reconstruction based on multilocus sequence analysis (MLSA) and 16S rRNA gene sequences and by emm typing combined with phenotypic characterization. Analysis of concatenated sequences of seven genes previously used for examination of viridans streptococci distinguished robust and coherent clusters. S. dysgalactiae consists of two separate clusters consistent with the two recognized subspecies dysgalactiae and equisimilis. Both taxa share alleles with S. pyogenes in several housekeeping genes, which invalidates identification based on single-locus sequencing. S. dysgalactiae, S. canis, and S. pyogenes constitute a closely related branch within the genus Streptococcus indicative of recent descent from a common ancestor, while S. equi is highly divergent from other species of the pyogenic group streptococci. The results provide an improved basis for identification of clinically important pyogenic group streptococci and explain the overlapping spectrum of infections caused by the species associated with humans.
Intentions and actual physical activity behavior change in a community‐based sample of middle‐aged women: Contributions from the theory of planned behavior and self‐determination theory

Abstract This two‐study research assessed intentions and actual physical activity behavior change in a community‐based sample of Canadian middle‐aged women by integrating concepts from two strong and complimentary psychological theories: the Theory of Planned Behavior (TPB) and Self‐Determination Theory (SDT). Specific objectives were 1) to examine associations among TPB variables, motivation, and intention to increase physical activity and 2) to examine the relative influence of intentions and motivation on reported physical activity behavior change over time. First, in a cross‐sectional study, French‐speaking women (n = 109) recruited from community‐based facilities completed validated measures of TPB variables (attitudes, perceived behavioral control, subjective norms, and intentions) and motivation (autonomous and controlled). In a follow‐up longitudinal study, one hundred and forty‐nine English‐speaking women from similar facilities completed these measures and reported on actual physical activity at baseline and at six months. In the first study, attitudes, perceived behavioral control, and autonomous motivation were significantly associated with physical activity intentions. In the second study, attitudes, subjective norms, and autonomous motivation were significantly related to intentions to increase physical activity. In turn, intentions predicted change in physical activity behavior over time; however, the relationship was modest. Results highlight the role of intentions in physical activity behavior change among middleaged women and are discussed in light of current research and theory. Future research directions are proposed
Acoustic startle at baseline and during acute alcohol withdrawal in replicate mouse lines selectively bred for high or low alcohol preference.

BACKGROUND Previous data in both rat and mouse genetic models suggest that there is a genetic relationship between acute alcohol withdrawal responses and innate alcohol drinking behavior. The purpose of the present study was to examine whether acute alcohol withdrawal responses, as measured by acoustic startle and prepulse inhibition (PPI) of acoustic startle, may be genetically related to innate differences in alcohol preference in 2 mouse lines selectively bred for high (HAP1 and HAP2) or low (LAP1 and LAP2) alcohol preference. Line differences in startle responses at baseline, prior to alcohol or saline treatment, were also measured. METHODS Alcohol-naive, male and female HAP1 (n = 35) and LAP1 (n = 32) and HAP2 (n = 43) and LAP2 (n = 40) mice were tested under baseline conditions and during withdrawal from a single injection of 4.0 g/kg alcohol or equal volume of saline at 4, 8, and 12 hours post-injection. RESULTS On most trial types, baseline startle responses and PPI were greater in both HAP lines than in both LAP lines, and startle responses were greater in males than in females. During acute alcohol withdrawal, both male LAP lines, and LAP1 females, showed reduced startle responses at the 4-hour time point during acute alcohol withdrawal. In contrast, both HAP1 males and females showed a trend toward enhanced startle at 4 hours in withdrawal. No clear differences in PPI during withdrawal were evident. CONCLUSIONS These findings indicate good evidence for a genetic relationship between greater baseline acoustic startle responses and PPI and high alcohol preference. Modest support for a genetic correlation between low alcohol preference and reduced startle responses at 4 hours in withdrawal was found in male mice. The suppression in acoustic startle during acute alcohol withdrawal in male LAP lines but not in male HAP lines suggests that a genetic propensity toward low alcohol preference may be related to greater sensitivity to alcohol as measured by acoustic startle responses during acute alcohol withdrawal.
Agency Practitioner Theories of How Advertising Works

In-depth interviews with senior-level agency practitioners (creative, planning, and account directors) were conducted to explore their thoughts about how advertising works. The study was designed to add to the understanding of the academician-practitioner gap in advertising by uncovering practitioners' hypothesized knowledge autonomy in the context of the sociological theory of professionalization. Results provide evidence for the existence of such autonomous practitioner knowledge schemas. Agency practitioners' core theories include a two-step "break through and engage" process and the longitudinal "mutation of effects" idea. They also believe in the primacy of emotional effects. Creativity is identified as the singularly most important factor in effectiveness, and agency professionals resisted any other regularities that may curtail creativity and result in formulaic advertising. Practitioners also emphasized the importance of defining boundary conditions when making claims about how advertising works, and identified strategic campaign objective, product category, medium used, and historical time period as key domains to consider. Implications for both academia and practice are offered, as are possible future research directions.
Combining Supervised and Unsupervised Parsing for Distributional Similarity

In this paper, we address the role of syntactic parsing for distributional similarity. On the one hand, we are exploring distributional similarities as an extrinsic test bed for unsupervised parsers. On the other hand, we explore whether single unsupervised parsers, or their combination, can contribute to better distributional similarities, or even replace supervised parsing as a preprocessing step for word similarity. We evaluate distributional thesauri against manually created taxonomies both for English and German for five unsupervised parsers. While for English, a supervised parser is the best single parser in this evaluation, we find an unsupervised parser to work best for German. For both languages, we show significant improvements in word similarity when combining features from supervised and unsupervised parsers. To our knowledge, this is the first work where unsupervised parsers are systematically evaluated extrinsically in a semantic task, and the first work to show that unsupervised parsing can complement and even replace supervised parsing, when used as a pre-processing feature.
A Random Effects Multinomial Logit Analysis of Using Medicare and VA Healthcare Among Veterans With Dementia

This study aimed to examine longitudinal patterns of VA-only use, dual VA and Medicare use, or Medicare-only use among veterans with dementia. Data on VA and Medicare use (1998–2001) were obtained from VA administrative datasets and Medicare claims for 2,137 male veterans with a formal diagnosis of Alzheimer's disease or vascular dementia enrolled in the National Longitudinal Caregiver Study. A random effects multinomial logit model accounting for unobserved individual heterogeneity was used to estimate the effects of patient and caregiver characteristics on use group over time. Compared to VA-only use, dual VA and Medicare use was associated with being white, married, higher education, having private insurance, Medicaid, low VA priority level, more functional limitations, and having lived in a nursing home or died in that year. Medicare-only use was associated with older age, being married, higher education, having private insurance, low VA priority level, living further from a VA Medical Center, having more comorbidities, functional limitations, and having lived in a nursing home or died. Veterans whose caregivers reported better health were more likely to be dual users, but those whose caregivers reported more comorbidities were more likely to use Medicare only. Different aspects of veterans' needs and caregiver characteristics have differential effect on where veterans seek care. Efforts to coordinate care between VA and Medicare providers are necessary to ensure patients receive high quality care.
VETSA: The Vietnam Era Twin Study of Aging

The Vietnam Era Twin Study of Aging (VETSA) is a longitudinal behavioral genetic study with a primary focus on cognitive and brain aging in men. It comprises a subset of over 1,200 twins from the Vietnam Era Twin Registry. Like many other studies of aging, the VETSA includes many different phenotypes, but there are some key features that distinguish it from most other behavioral genetic aging studies. First, the initial assessment was conducted when all participants were middle-aged. Second, the age range of participants is narrow; all were in their 50s at the time of the initial recruitment. Third, the study includes an extensive and demanding neurocognitive test battery that was designed to provide good coverage of different cognitive abilities and avoid ceiling effects in middle-aged adults. Fourth, young adult cognitive test data (at an average age of 20 years) are available to provide a gauge of cognitive change. These features make the VETSA ideal for studying the heterogeneity of within-individual trajectories from midlife to old age, and for early detection of risk factors for cognitive decline.