Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of dietary boron supplementation on egg production, shell quality, and calcium metabolism in aged broiler breeder hens.

Three experiments were conducted using aged broiler breeder hens (greater than 60 wk) to investigate the effects of supplemental B on egg production (EP), shell quality, and Ca metabolism. Experiment 1 had a 2 x 2 factorial arrangement of treatments: 1) high Ca (3.5%); 2) high Ca plus B; 3) low Ca (1.5%); and 4) low Ca plus B; using 32 60-wk-old hens. The B levels were basal and 100 ppm supplemental for the first 2 wk of the experiment and reduced to 60 ppm for the remaining 3 wk. Egg production, shell thickness (ST), and egg specific gravity (SG) were recorded weekly. In Experiment 2, 40 60-wk-old hens were divided into two groups: high and low shell quality. Each group was further divided into two subgroups and fed a low-Ca basal diet with or without supplemental B. The level of B supplementation and the experimental period was the same as in Experiment 1. In Experiment 3, 52 75-wk-old hens were force-molted. After molting, 36 hens were fed a commercial layer diet with the remaining 16 hens fed the control diet supplemented with 100 ppm B. Blood samples were taken during the nonlaying and laying periods, respectively. The results showed that B significantly (P less than .05) depressed EP in Experiment 1 but not in Experiments 2 and 3. Supplemental B decreased plasma Ca when hens were fed a diet containing high Ca levels (3.5%). Supplemental B did not affect SG, ST, or Ca retention, but did significantly increase tibial bone ash percentage (P less than .05). (ABSTRACT TRUNCATED AT 250 WORDS)
Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway

Cisplatin has been used effectively in the treatment of hepatocellular carcinoma (HCC). Long noncoding RNAs (lncRNAs) were recently reported to contribute to the pathogenesis and progression of HCC. Their molecular mechanism related to cisplatin treatment remains unclear. The purpose of this study is to identify specific lncRNAs and to clarify their functions in HCC after cisplatin exposure. Reannotation and identification of differentially expressed lncRNAs were performed using the microarray data set GSE38122 in the Gene Expression Omnibus database. Four significantly differentially expressed lncRNAs (RP11-134G8.8, RP11-612B6.2, RP11-363E7.4 and RP1-193H18.2) were identified in HepG2 cells exposed to cisplatin by bioinformatics methods. The upregulated RP11-134G8.8 and RP11-363E7.4 and the downregulated RP1-193H18.2 were confirmed by reverse transcription-quantitative polymerase chain reaction. Furthermore, 57 significant co-expressing genes and their corresponding pathways were annotated and identified. The p53 signaling pathway showed the most significant difference among all pathways. Based on these results, the cell cycle and three key genes, cyclin-dependent kinase inhibitor 1A (CDKN1A, also known as p21), tumor protein p53 inducible protein 3 (TP53I3) and wild-type p53-induced phosphatase 1 (Wip1, also known as PPM1D), were examined. CDKN1A, TP53I3 and PPM1D were all downregulated by RP1-193H18.2 but upregulated by RP11-134G8.8 and RP11-363E7.4. And obvious S phase arrest was induced by cisplatin treatment for 24 h in HepG2 cells. Finally, the immunofluorescence results showed upregulation of TP53I3 and Wip1 and downregulation of p21 at the protein level. The results suggested that the lncRNAs RP11-134G8.8, RP11-363E7.4 and RP1-193H18.2, and their co-expression genes, which annotated into the p53 signaling pathway, could be potential targets for cisplatin treatment.
Influence of Scouring Operations on the Properties of Control and DMEU-Finished Cotton Drill Fabric

Desized-mercerized (DM) cotton drill was scoured in the laboratory using three techniques— viz. pressure-kier-boil (PK), open-kier-boil (OK), and pad-roll-steam (PS). From the physicochemical data obtained on these fabrics, the descending order of purification attained is PK > OK > PS > DM. However, the evaluation for resilience and strength-abrasion properties has shown that the better the purification attained, the greater is the loss in these properties. On DMEU finishing, the improvement in conditioned wrinkle-recovery angle shows a descending order similar to the above with increasing purification. However, the gradation in the overall performance of DMEU-finished fabrics at the wash-and-wear level is DM>PS>OK>PK, and at the durable-press level it is PS>DM>OK>PK. The values for the slopes of these profiles show a reverse trend.
Explaining First Impressions: Modeling, Recognizing, and Explaining Apparent Personality from Videos

Explainability and interpretability are two critical aspects of decision support systems. Within computer vision, they are critical in certain tasks related to human behavior analysis such as in health care applications. Despite their importance, it is only recently that researchers are starting to explore these aspects. This paper provides an introduction to explainability and interpretability in the context of computer vision with an emphasis on looking at people tasks. Specifically, we review and study those mechanisms in the context of first impressions analysis. To the best of our knowledge, this is the first effort in this direction. Additionally, we describe a challenge we organized on explainability in first impressions analysis from video. We analyze in detail the newly introduced data set, the evaluation protocol, and summarize the results of the challenge. Finally, derived from our study, we outline research opportunities that we foresee will be decisive in the near future for the development of the explainable computer vision field.
The MACHO Project LMC Variable Star Inventory. VII. The Discovery of RV Tauri Stars and New Type II Cepheids in the Large Magellanic Cloud

We report the discovery of RV Tauri stars in the Large Magellanic Cloud (LMC). In light- and color-curve behavior, the RV Tauri stars appear to be a direct extension of the type II Cepheids to longer periods. A single period-luminosity-color relationship is seen to describe both the type II Cepheids and the RV Tauri stars in the LMC. We derive the relation V0 = 17.89(±0.20)-2.95(±0.12) log P + 5.49(±0.35)⟨(V - R)0⟩, which is valid for type II Cepheids and RV Tauri stars in the period range 0.9 < log P < 1.75. Assuming a distance modulus to the LMC of 18.5, the relation in terms of the absolute luminosities becomes MV = -0.61(±0.20)-2.95(±0.12) log P + 5.49(±0.35)⟨(V - R)0⟩.
Effects of feeding Fusarium moniliforme culture material, containing known levels of fumonisin B1, on the young broiler chick.

The effects of feeding Fusarium moniliforme culture material, containing known concentrations of fumonisin B1 (FB1), were studied in broiler chicks. Day-old chicks were allotted randomly to dietary treatments containing 0, 1.02, 2.04, 3.06, 4.08, 5.10, 6.12, and 7.14% fumonisin culture material (FCM). These levels of FCM supplied 0, 75, 150, 225, 300, 375, 450, and 525 mg of FB1/kg of feed. Each dietary treatment was fed to four pen replicates of six birds each for 21 days. Chicks fed FCM that supplied 450 and 525 mg FB1/kg diet had lower (P < .05) feed intakes and BW gains; increased (P < .05) liver and kidney weights; and increased (P < .05) mean cell hemoglobin, and mean cell hemoglobin concentrations. Compared with controls, chicks fed FCM had increased (P < .05) free sphinganine levels and sphinganine:sphingosine ratios. Treatment-associated histological lesions were only observed in the liver of chicks fed diets containing FCM that supplied 225 mg FB1/kg or higher. Diets containing FCM that supplied levels as low as 75 mg FB1/kg affected the physiology of chicks by increasing free sphinganine levels and sphinganine:sphingosine ratios. Because inhibition of sphingolipid biosynthesis has been hypothesized as the mechanism of action of FB1, this suggests that diets containing 75 mg FB1/kg FCM may be toxic to young broiler chicks.
Crack Propagation Calculations for Optical Fibers under Static Bending and Tensile Loads Using Continuum Damage Mechanics

Static fatigue behavior is the main failure mode of optical fibers applied in sensors. In this paper, a computational framework based on continuum damage mechanics (CDM) is presented to calculate the crack propagation process and failure time of optical fibers subjected to static bending and tensile loads. For this purpose, the static fatigue crack propagation in the glass core of the optical fiber is studied. Combining a finite element method (FEM), we use the continuum damage mechanics for the glass core to calculate the crack propagation path and corresponding failure time. In addition, three factors including bending radius, tensile force and optical fiber diameter are investigated to find their impacts on the crack propagation process and failure time of the optical fiber under concerned situations. Finally, experiments are conducted and the results verify the correctness of the simulation calculation. It is believed that the proposed method could give a straightforward description of the crack propagation path in the inner glass core. Additionally, the predicted crack propagation time of the optical fiber with different factors can provide effective suggestions for improving the long-term usage of optical fibers.
Leptosphaeria maculans AvrLm9: a new player in the game of hide and seek with AvrLm4-7.

Blackleg disease of Brassica napus caused by Leptosphaeria maculans (Lm) is largely controlled by the deployment of race-specific resistance (R) genes. However, selection pressure exerted by R genes causes Lm to adapt and give rise to new virulent strains through mutation and deletion of effector genes. Therefore, a knowledge of effector gene function is necessary for the effective management of the disease. Here, we report the cloning of Lm effector AvrLm9 which is recognized by the resistance gene Rlm9 in B. napus cultivar Goéland. AvrLm9 was mapped to scaffold 7 of the Lm genome, co-segregating with the previously reported AvrLm5 (previously known as AvrLmJ1). Comparison of AvrLm5 alleles amongst the 37 re-sequenced Lm isolates and transgenic complementation identified a single point mutation correlating with the AvrLm9 phenotype. Therefore, we renamed this gene as AvrLm5-9 to reflect the dual specificity of this locus. Avrlm5-9 transgenic isolates were avirulent when inoculated on the B. napus cultivar Goéland. The expression of AvrLm5-9 during infection was monitored by RNA sequencing. The recognition of AvrLm5-9 by Rlm9 is masked in the presence of AvrLm4-7, another Lm effector. AvrLm5-9 and AvrLm4-7 do not interact, and AvrLm5-9 is expressed in the presence of AvrLm4-7. AvrLm5-9 is the second Lm effector for which host recognition is masked by AvrLm4-7. An understanding of this complex interaction will provide new opportunities for the engineering of broad-spectrum recognition.
Characteristics of Implicit Sensorimotor Adaptation Revealed by Task-irrelevant Clamped Feedback

Sensorimotor adaptation occurs when there is a discrepancy between the expected and actual sensory consequences of a movement. This learning can be precisely measured, but its source has been hard to pin down because standard adaptation tasks introduce two potential learning signals: task performance errors and sensory prediction errors. Here we employed a new method that induces sensory prediction errors without task performance errors. This method combines the use of clamped visual feedback that is angularly offset from the target and independent of the direction of motion, along with instructions to ignore this feedback while reaching to targets. Despite these instructions, participants unknowingly showed robust adaptation of their movements. This adaptation was similar to that observed with standard methods, showing sign dependence, local generalization, and cerebellar dependency. Surprisingly, adaptation rate and magnitude were invariant across a large range of offsets. Collectively, our results challenge current models of adaptation and demonstrate that behavior observed in many studies of adaptation reflect the composite effects of task performance and sensory prediction errors.
Fibres of Failure: Classifying errors in predictive processes

We describe Fibres of Failure (FiFa), a method to classify failure modes of predictive processes using the Mapper algorithm from Topological Data Analysis. Our method uses Mapper to build a graph model of input data stratified by prediction error. Groupings found in high-error regions of the Mapper model then provide distinct failure modes of the predictive process. We demonstrate FiFa on misclassifications of MNIST images with added noise, and demonstrate two ways to use the failure mode classification: either to produce a correction layer that adjusts predictions by similarity to the failure modes; or to inspect members of the failure modes to illustrate and investigate what characterizes each failure mode.
Effect of application of biogas slurry with potassium on orchard soil properties and soil microorganism and fruit quality.

【Objective】 The present experiment is aiming at studying how the coordination use of biogas slurry and potassium in apple orchard influences the physiochemical characteristics of its soil, the quantity of microorganisms in its soil, and its fruit quality, and thus providing a theoretical basis for properly use of biogas slurry in Weibei Rainfed Highland of Shaanxi. 【Method】 The 10-year-old apple trees were used as test materials in the experiment and the effects of combined use of biogas slurry and potassium in apple orchard on the physiochemical characteristics of soil, the quantity of microorganisms in soil, and fruit quality were studied to screen the application rate of biogas slurry alone and the biogas slurry together with potassium. 【Result】 The results showed that biogas slurry dressing decreased soil bulk density and increased soil porosity, available nitrogen, and available potassium. Biogas slurry at 100 kg/tree decreased soil bulk density by 10.6% and increased soil porosity by 7.6% compared with the control. Biogas slurry at 50 kg/tree with potassium at 1 kg increased soil potassium by 20.5% compared with the control. Biogas slurry applied with potassium increased the number of soil bacteria, fungi, and antinomies. Biogas slurry applied at 100 kg increased the numbers of bacteria,fungi and actinomycetes by 132.7%, 38.3%, and 58.2% compared with the control. There was a promoting effect of combined application of biogas slurry with potassium on apple red fruit surface area rate, average single fruit weight, firmness, soluble solids and anthocyanin. Biogas slurry applied at 50 kg/tree and potassium applied at 0.5kg/tree increased anthocyanidin by 48%, colored area increased by 29.9% compared with the control. 【Conclusion】 The study proposed that biogas slurry applied at 100 kg per plant and biogas slurry applied at 50 kg with K fertilizer 0.5 kg per plant were the best for apple production and should be popularized.
Cytomorphologic patterns of Pap and PAS‐stained oral exfoliative cytology smears in adult Saudi diabetic patients as compared to healthy controls

Diabetes mellitus (DM) is one of the most common metabolic disorders worldwide and 425 million people were estimated to have diabetes by 2017. Oral manifestations reflect the metabolic control of diabetes. Exfoliative cytology using Papanicolaou (Pap) and periodic acid Schiff (PAS) stains is a practical technique to evaluate oral epithelial cytomorphologic changes in diabetes.
Factors influencing scores on the social responsiveness scale.

BACKGROUND The Social Responsiveness Scale (SRS) is a parent-completed screening questionnaire often used to measure autism spectrum disorders (ASD) severity. Although child characteristics are known to influence scores from other ASD-symptom measures, as well as parent-questionnaires more broadly, there has been limited consideration of how non-ASD-specific factors may affect interpretation of SRS scores. Previous studies have explored effects of behavior problems on SRS specificity, but have not addressed influences on the use of the SRS as a quantitative measure of ASD-symptoms. METHOD Raw scores (SRS-Raw) from parent-completed SRS were analyzed for 2,368 probands with ASD and 1,913 unaffected siblings. Regression analyses were used to assess associations between SRS scores and demographic, language, cognitive, and behavior measures. RESULTS For probands, higher SRS-Raw were associated with greater non-ASD behavior problems, higher age, and more impaired language and cognitive skills, as well as scores from other parent report measures of social development and ASD-symptoms. For unaffected siblings, having more behavior problems predicted higher SRS-Raw; male gender, younger age, and poorer adaptive social and expressive communication skills also showed small, but significant effects. CONCLUSIONS When using the SRS as a quantitative phenotype measure, the influence of behavior problems, age, and expressive language or cognitive level on scores must be considered. If effects of non-ASD-specific factors are not addressed, SRS scores are more appropriately interpreted as indicating general levels of impairment, than as severity of ASD-specific symptoms or social impairment. Additional research is needed to consider how these factors influence the SRS' sensitivity and specificity in large, clinical samples including individuals with disorders other than ASD.
MINE: Mutual Information Neural Estimation

This paper presents a Mutual Information Neural Estimator (MINE) that is linearly scalable in dimensionality as well as in sample size. MINE is back-propable and we prove that it is strongly consistent. We illustrate a handful of applications in which MINE is succesfully applied to enhance the property of generative models in both unsupervised and supervised settings. We apply our framework to estimate the information bottleneck, and apply it in tasks related to supervised classification problems. Our results demonstrate substantial added flexibility and improvement in these settings.
Quantification and Correlation of Oral Candida with Caries Index Among Different Age Groups of School Children: A Case–Control Study

Background: Dental caries is the most common infectious disease affecting humans and is the predominant cause of tooth loss in children. Although Candida's role in dental caries has been studied extensively, limited homogenous studies have been conducted and none have been found, that associate Candida with dental caries, while correlating it to different age groups. Aim: The study aimed to quantify oral Candida in school children and correlate candidal carriage to the caries index and further analyze an age association. Subjects and Methods: Decayed-Filled teeth/Decayed-Missing-Filled Teeth (dft/DMFT) index scores of 150 subjects were evaluated, and concentrated oral rinse samples were collected from each participant for mycologic investigation. Based on the age and caries activity, the participants were categorized into three groups consisting of 50 each such as Group-I (caries active participants of 6–12 years age), Group-II (caries active participants in 13–18 years age), and Group-III (caries-free participants in 6–18 years age); CHROMagar™ was used as a primary culture medium for candidal growth. The data was statistically analyzed using Unpaired t-test, Chi-square test and Spearman's rank order. Results: The results demonstrated that as age increases, the dft/DMFT scores as well as the candidal growth decreased. In addition, the oral candidal carriage levels were found to be low in caries-free group (Group-III) when compared to the study groups. Conclusion: The presence of Candida was directly related to the caries status and inversely proportional to the age.
The effect of rapeseed meal and methimazole on levels of plasma hormones in growing broiler cockerels.

The effects of feeding a heat treated rapeseed meal, which has goitrogenic properties, on the concentrations of plasma pituitary and thyroid gland hormones was investigated in broiler cockerels of between 3 and 10 weeks of age. For purposes of comparison, two other groups were included in the study; one was fed the goitrogen, methimazole, and the other a normal control diet. The hormones measured were thyroxine (T4), triiodothyronine (T3), growth hormone (GH), prolactin, and luteinizing hormone (LH). In birds fed methimazole the thyroid glands were greatly enlarged, the concentrations of plasma T4 and T3 were depressed and the concentrations of growth hormone, prolactin, and LH were elevated. The high level of plasma LH in the birds fed methimazole was not due to the absence of sufficient concentrations of plasma testosterone to exert a negative feedback effect. Although the inclusion of rapeseed meal in the diet caused the thyroid glands to enlarge, the concentrations of all the hormones studied, with the exception of T3, were similar to those in the control birds. However, there was a tendency, which was more pronounced in birds of between 3 and 5 weeks of age, for rapeseed meal to depress the concentrations of plasma T4, GH, and LH and to increase the concentration of plasma prolactin. The most significant observation was that between 3 and 5 weeks of age the inclusion of rapeseed meal in the diet significantly (P less than .001) depressed the concentration of plasma T3.
Median Nerve Conduction in Healthy Nigerians: Normative Data

Background: Because of lack of local normative data, electrodiagnostic laboratories in Nigeria apply standard values generated in the USA and Europe to diagnose different median nerve abnormalities. Aim: To develop normative values for motor and sensory median nerve conduction studies (NCSs) in Nigerian population. Subjects and Methods: In a cross-sectional study design, a total of 200 healthy volunteers were selected after clinical evaluation to exclude systemic or neuromuscular disorders. NCS of the median nerves was conducted on all the healthy volunteers according to a standardized protocol. The data included in the final analysis were amplitude, latency, and nerve conduction velocity. Ethical approval was obtained for the study. Results: The reference range for median nerve (motor) velocity, distal latency, and amplitude were 49.48–66.92, 1.95–4.52, and 4.3–11.3, respectively. The reference range for median nerve F-wave latency was 44.8–70.5. The reference range for median nerve (sensory) velocity, distal latency, and amplitude were 44.8–70.5, 1.98–4.52, and 16.6–58.4, respectively. Conclusion: Reference values for the nerve conduction parameters of the median (motor and sensory) in the study population were similar to those obtained in the literature.
A Paradigm-Shift in Molecular Therapy of Cystic Fibrosis? Gene Therapy versusPharmacological Correction of Protein Function

Since the early 1990ies Cystic Fibrosis (CF), an autosomal-recessive disease due to mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene and its protein product, is seen as one of the main disease-targets for gene therapy . About 2000 different CF-causing gene-mutations have been identified. Some mutations are particularly common in certain populations, most notably a trinucleotide deletion called DeltaF508, which is observed in 70-80% of the CF-alleles in Caucasians. The presently most pursued gene therapy strategy for autosomal recessive diseases such as CF aims at introducing a functional copy of the mutated gene into the affected cells of the patient. This gene sequence should then provide sufficient non-mutated protein as required for normal cell function. This strategy has the great advantage that it should work for any kind of CFTR-mutation, irrespective of its exact sequence.