Miracle-dz/UniFAR-FTUs huggingface dataset:
Career Concerns and Management Earnings Guidance

This study provides evidence that managers' career concerns affect their earnings guidance decisions. We hypothesize that CEOs who are relatively more concerned about assessments of their abilities have stronger incentives to guide the market expectations of earnings downwards to increase the likelihood of meeting or beating the expectations. Consistent with this hypothesis, we find that (i) short-tenured CEOs, CEOs promoted from inside the firm, and nonfounder CEOs are more likely to provide downward earnings guidance when they have bad news, and (ii) their downward guidance tends to be more conservative. In response, analysts revise earnings forecasts less for the downward guidance provided by more career-concerned CEOs. This indicates that analysts rationally incorporate these CEOs' stronger incentives to be conservative in their earnings guidance. Consequently, we find that CEOs with greater career concerns are not more likely to beat the market expectations, even when they provide more conservative downward guidance. [ABSTRACT FROM AUTHOR]
The Impact of Nonclinical Factors on Care Use for Patients with Depression: A STAR*D Report

Introduction: This article presents baseline findings that describe how nonclinical factors were associated with patient use of psychiatric and general medical care and how those relationships changed after patients enrolled in the 41‐site Sequenced Treatment Alternatives to Relieve Depression study (STAR*D). Aims: STAR*D offered adult outpatients with major depression diligently delivered, measurement‐based care. To achieve full remission within a tolerable medication dose, recommendations for treatment based on routine symptom and side‐effect measurements were discussed with patients by clinical research coordinators and offered to clinicians who could flexibly tailor that guidance to accommodate individual patient needs. Medications were provided gratis. Pre‐ and post‐enrollment data came from provider records and from patient face‐to‐face, telephone, and computer‐assisted surveys. Two‐part nested mixed models assessed patient likelihood and volume of mental and general medical care services. Results: Prior to enrollment, predisposing (gender, race, education, and care attitude), affordability (private insurance), and clinical factors (depressive symptoms and mental and physical functioning) were found to be important drivers of patient use of psychiatric and general medical care. After STAR*D enrollment, however, predisposing factors were less important drivers of psychiatric service use but remained important drivers of general medical care. Conclusions: Data suggest diligent, measurement‐based mental health programs may reduce race, gender, and education disparities in the use of needed mental health care.
Environmental uncertainty and forward integration in marketing: theory and meta‐analysis

Purpose – This paper aims to present a meta‐analysis to test the competing hypotheses that arise from structural contingency theory (SCT) and transaction cost analysis (TCA) about how environmental uncertainty affects the strategic marketing policy of forward vertical integration (VI). Design/methodology/approach – The meta‐analysis focuses on directional hypothesis tests rather than effect sizes in a set of 84 tests drawn from 29 published studies. It employs the C‐OAR elements of Rossiter's C‐OAR‐SE framework to validate construct definitions and their measures within these studies.Findings – Although the results confirm the TCA hypothesis that asset specificity favours forward VI, the results for the effect of environmental uncertainty on forward VI do not favour either of the two competing hypotheses, but instead show that methodological orientation, international context, and historical time period moderate effects across studies and tests.Research limitations/implications – The findings imply that th.
Risk factors analysis for pneumocystis jiroveci pneumonia (PCP) in patients with haematological malignancies and pneumonia

A retrospective matched case-control investigation was conducted to assess risk factors suggesting Pneumocystis jiroveci pneumonia (PCP) when pneumonia occurs in adult patients with haematological malignancies. Cases and controls included were HIV-negative, presented with pneumonia and had benefited from a bronchoalveolar lavage (BAL). The presence of Pneumocystis jiroveci cysts was systematically investigated by cytochemical staining and/or immunofluorescence. Cases were patients with Pneumocystis jiroveci cysts isolated on BAL fluid (n=31, mean age 51±14 y; range 20–73 y). Controls were patients without Pneumocystis jiroveci cysts (n=62, mean age 54±13 y; range 25–75 y) and were matched to case patients by age and y of pneumonia diagnosis. Statistical analysis indicated that the following factors were associated with PCP: vincristine (p=0.009, odds ratio (OR)=2.11, 95% confidence interval (CI): 1.19–3.72), a daily corticosteroid therapy for more than 1 month (p=0.05) during the past y, and a lymphocyte count less than 0.5×109/l on the d of pneumonia diagnosis (p=0.04). Clinicians should be aware, in order to evoke this diagnosis when pneumonia occurs in patients with these risk factors. The goal of this exploratory study was to identify risk factors that could eventually be further investigated by a larger prospective multicentre study.
Student Motivation and Learning Strategies of Students from USA, China and Bangladesh

To better understand the motivation and strategies used by students around the world, a comparative study among three different countries was performed.The current study used the Motivated Strategies for Learning Questionnaire (MSLQ) questionnaire to collect responses from students in public and private universities of Bangladesh.The results were also used to compare the differences between public and private universities of Bangladesh, as there is a national debate on the quality of these two types of universities in Bangladesh.The number of students that participated in this study was 164 with 143 from private universities and 21 from public universities. The number of lower responses from public universities may be an indicator of their lack of motivation to participate in this study. MSLQ questionnaires have been used and adapted by universities across the world as a valid instrument to measure the level of motivation and the learning process.The survey consists of 18 questions to evaluate motivation and learning strategies. The results of the responses from Bangladesh were compared with a previous study between students of USA and China [9] . There was no significant difference between public and private universities in Bangladesh in most of the categories.However, some differences were observed among these three countries indicating that students from different geographical regions may have different levels of motivation and learn differently. DOI: http://dx.doi. org/10.11591/ijere.v3i4. 6288 Normal 0 false false false MS ZH-CN X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:. 0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} table.MsoTableGrid {mso-style-name:"Table Grid"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-unhide:no; border:solid windowtext 1.0pt; mso-border-alt:solid windowtext . 5pt; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-border-insideh:. 5pt solid windowtext; mso-border-insidev:. 5pt solid windowtext; mso-para-margin:0in; mso-para-margin-bottom:. 0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";}
Why do regime‐switching models forecast so badly?

Most non-linear techniques give good in-sample fits to exchange rate data but are usually outperformed by random walks or random walks with drift when used for out-of-sample forecasting. In the case of regime-switching models it is possible to understand why forecasts based on the true model can have higher mean squared error than those of a random walk or random walk with drift. In this paper we provide some analytical results for the case of a simple switching model, the segmented trend model. It requires only a small misclassification, when forecasting which regime the world will be in, to lose any advantage from knowing the correct model specification. To illustrate this we discuss some results for the DM/dollar exchange rate. We conjecture that the forecasting result is more general and describes limitations to the use of switching models for forecasting. This result has two implications. First, it questions the leading role of the random walk hypothesis for the spot exchange rate. Second, it suggests that the mean square error is not an appropriate way to evaluate forecast performance for non-linear models. Copyright © 1999 John Wiley & Sons, Ltd.
Globalisation, informalisation and the state in the Indian garment industry

Globalisation has affected the industrial trajectories of developing countries, producing an increasing disarticulation between the management of production and regimes of labour control. While production regimes have been projected into the global arena, labour regimes have remained apparently anchored to regulatory mechanisms provided by local social structures, and gone through increasing processes of informalisation. Examining the case of the Indian garment sector, this paper argues that the informalisation of labour should not be conceived as necessarily taking place ‘in the shadow of the state’. In fact, in the case presented here, the state was a strong active agency behind the process of informalisation, which it supported through formal policies and through its progressive alignment with the interests of capital.
Schooltime subjective sleepiness and performance in Italian primary school children

ABSTRACT Despite its clinical importance, the issue of the diurnal time course of sleepiness and performance in children remains largely unexplored. The objective of this study is to draw a profile of daytime subjective sleepiness and performance, at simple and complex tasks, in a cohort of Italian primary school children.To this aim, a sample of 316 children (age range: 5–11 years; mean 8.2 ± 1.5) was recruited and sub-divided into three groups, according to age: Group 1 (5–7 years; N = 127), Group 2 (8–9 years; N = 108), Group 3 (10–11 years; N = 81). Subjective sleepiness and simple performance were evaluated, respectively, through the Pictorial Sleepiness Scale and the Simple Reaction Time Task. Executive functions were addressed by means of the “Go/No-Go Task. ” Measurements were made in the children’s class three times a day, one day a week over a 3-week period in order to reliably reflect the habitual time course of sleepiness and performance, within the following time intervals: a) 8:30 am–10:30 am; b) 11 am–1 pm; c) 2 pm–4 pm.For the global sample, a significant increase of subjective sleepiness was found at the end of school day (2–4 pm), although at relatively low levels. No significant differences were observed in reaction times across the day, whereas a significant worsening was detected in performance at complex task already since mid-morning. Significant correlations were found between subjective sleepiness and complex performance at all points.Slight age-related differences were found in the time courses of subjective sleepiness: in fact, a significant overday reduction of vigilance levels, from mid-morning onwards, was observed in children aged 5–9 years, but not in the older children (10–11 years). However, the daily time course of both simple and complex performances did not differ among children of the three age groups. Our results show changes in vigilance and cognitive functions across a typical school day in childhood, as well as age-related differences in sleepiness profile, that we suggest to thoroughly consider when conceiving chronopsychological interventions in the school context.
An Investigation of Factors Affecting Job Satisfaction

ABSTRACT The measurement of job satisfaction has become an important issue in tourism because this industry requires a great interaction between the contact personnel (frontline employees) and the individual customer and because quality perceptions are evaluated mostly on the basis of the performance of subjective (intangible) criteria. Thus, the extent to which employees are satisfied with what they are responsible for may directly influence the level of customer satisfaction with their services. Using an improved form of job descriptive index, this study aims to evaluate the predictors of hotel employees' both job satisfaction and their intention to stay in the hotel business. The discussion is based upon the findings of a survey carried out among those working in the Turkish hotel industry. Findings suggest that such attributes as the work itself, supervision, and promotion are the determinants of the level of overall job satisfaction. The level of overall job satisfaction in turn leads to changes in the employees' intention to continue working in the hotel business. Theoretical and practical implications are also discussed.
Who Takes Care of Whom in the United States? Time Transfers by Age and Sex

type="main"> Non-monetary transfers of time represent a largely unknown, yet pivotal component, of the support system in the United States. We map flows of time transfers, by age and sex, related to informal childcare and adult care in the US. We develop methods to estimate intra- and inter-household time transfers using data from the American Time Use Survey (2011–2013). We summarize the results in matrices of time flows by age and sex for the general US population, as well as for the “sandwich generation. ” Most time transfers flow downwards from parents to young children, with relevant gender differences. The time produced by the sandwich generation is directed toward a more diverse population spectrum, including substantial intra-generational transfers to spouses. Extrapolations based on our findings reveal a projected rise in demand, relative to supply, of informal care, indicating that, to maintain current levels of care, US society will have to rely more heavily either on the market or on an increased effort of caregivers.
Prevention and Treatment of Chemotherapy-Induced Neutropenia with the Biosimilar Filgrastim: A Non-Interventional Observational Study of Clinical Practice Patterns

Background: Biosimilars are similar but non-identical versions of existing biological drugs. The HEXAFIL study was an observational study that assessed the clinical usage, safety and efficacy of the biosimilar filgrastim in routine clinical practice in Germany. Patients and Methods: A total of 1,337 cancer patients received the biosimilar filgrastim for primary prophylaxis (PP), secondary prophylaxis (SP) or interventional treatment (TX) plus chemotherapy. Data including neutropenic complications and adverse events (AEs) were documented for up to 3 consecutive cycles. Results: In cycle 1, 44.9% of the patients received the biosimilar filgrastim as PP, 31.0% as SP, and 23.6% as TX. Approximately 90% of the patients required no modifications to their chemotherapy regimen, with lower rates among the PP/SP versus the TX patients. Neutropenic complications occurred in 7.9%, 6.9%, and 3.9% of the patients (cycles 1, 2, and 3, respectively). Only 1.8% of the patients experienced febrile neutropenia during cycle 1. Earlier and longer filgrastim treatment reduced grade 3/4 leukopenia and neutropenic complications. The observed safety/tolerability profile was as expected; the most common AE (4.3%) was musculoskeletal back/bone pain. Conclusion: In this observational real-life study of clinical practice, the biosimilar filgrastim was effective and well tolerated, with results consistent with those reported in phase II and phase III trials.
Osteotomy at low-speed drilling without irrigation versus high-speed drilling with irrigation: an experimental study.

INTRODUCTION Excessively traumatic surgery can adversely affect the maturation of bone tissue and consequently diminish the predictability of osseointegration so the mechanical and thermal damage should be minimized during surgical procedure. The purpose of this study is to evaluate immediate histological alterations in rabbit tibias, produced by low speed drilling (50 rpm) without irrigation and conventional drilling (800 rpm) under profuse irrigation. MATERIAL AND METHODS Thirty-six implant osteotomies were created in the tibias of 6 White female rabbits. Drilling began with a 1.5 mm round bur, followed by 2.0 mm, 2.5 mm and 3.5 mm helical drills. The posterior tibial cortex was evaluated as the positive control, and it was preserved during the surgical procedure. The receptor beds were collected for histological analysis. RESULTS All defects showed regular edges. Hematoxylin eosin (HE) sections showed that both techniques preserved the bone structure and the presence of living cells. No histological differences between the two surgical drilling techniques were found. CONCLUSIONS Based on our results, we can conclude that the effects of implant site preparation on bone by low speed drilling (50 rpm) without irrigation and conventional drilling (800 rpm) under abundant irrigation are similar. Both surgical drilling techniques preserve bone-cell viability and the clinician can decide which drilling technique to use, based on other criteria.
Environmentally Sustainable Development through Stakeholder Engagement in Developed and Emerging Countries

This cross-country study investigates the antecedents and outcomes of corporate environmental responsibility (CER) practices in developed and emerging countries. Based on stakeholder and institutional theory, we conducted an empirical study among firms in Germany, USA, India and China. We found support for a significant positive relationship between regulatory, market and social stakeholder influences, CER practices and business outcomes in the total and individual country samples. Regarding country differences, our data reveal significant similarities and differences between developed and emerging countries. Market stakeholder influences are stronger in developed countries, whereas regulatory and social stakeholder influences do not differ significantly between the two country groups. The relationship between CER practices and positive business outcomes is stronger in emerging than in developed countries. Implications for institutional theory and organizations are outlined. Copyright © 2014 John Wiley & Sons, Ltd and ERP Environment
Platform Investments and Volatility Exchange Rates: Direct Investment in the U.S. by Japanese Electronic Companies

This study examines the effects of previous entry on the subsequent decisions of Japanese electronics companies to invest in the United States. By gathering data at the firm level, the empirical analysis provides a fine-grain sorting out of firm and industry effects on foreign direct investment decisions. The findings show that investment behavior is highly heterogeneous across firms and reflects their individual technological capabilities and their history of previous investments in the United States. Real exchange rate levels are also important. The results suggest that initial investments serve as platforms for subsequent entry, with the timing of entry triggered by movements in real exchange rates. Copyright 1996 by MIT Press.
Amphibian Limb Regeneration: Rebuilding a Complex Structure

The ability to regenerate complex structures is widespread in metazoan phylogeny, but among vertebrates the urodele amphibians are exceptional. Adult urodeles can regenerate their limbs by local formation of a mesenchymal growth zone or blastema. The generation of blastemal cells depends not only on the local extracellular environment after amputation or wounding but also on the ability to reenter the cell cycle from the differentiated state. The blastema replaces structures appropriate to its proximodistal position. Axial identity is probably encoded as a graded property that controls cellular growth and movement through local cell interactions. The molecular basis is not understood, but proximodistal identity in newt blastemal cells may be respecified by signaling through a retinoic acid receptor isoform. The possibility of inducing a blastema on a mammalian limb cannot be discounted, although the molecular constraints are becoming clearer as we understand more about the mechanisms of urodele regeneration.
The Evolution of Sex: a Perspective from the Fungal Kingdom

SUMMARY Sex is shrouded in mystery. Not only does it preferentially occur in the dark for both fungi and many animals, but evolutionary biologists continue to debate its benefits given costs in light of its pervasive nature. Experimental studies of the benefits and costs of sexual reproduction with fungi as model systems have begun to provide evidence that the balance between sexual and asexual reproduction shifts in response to selective pressures. Given their unique evolutionary history as opisthokonts, along with metazoans, fungi serve as exceptional models for the evolution of sex and sex-determining regions of the genome (the mating type locus) and for transitions that commonly occur between outcrossing/self-sterile and inbreeding/self-fertile modes of reproduction. We review here the state of the understanding of sex and its evolution in the fungal kingdom and also areas where the field has contributed and will continue to contribute to illuminating general principles and paradigms of sexual reproduction.
Short intensive exercise increases the migratory activity of mesenchymal stem cells

Background: It is known that exercise increases the number of stem cells within the circulation; however, it has not been clear which cellular processes are responsible for this increase. To answer this question, we analysed the influence of athletes’ blood sera on human mesenchymal stem cells (MSC). Methods: Sera were taken before and after short intensive exercise. As cellular parameters of MSC proliferation, apoptosis and migratory activity were analysed. Results: A change in stimulation of proliferation or apoptosis was not seen after exercise. In contrast, the migratory activity of MSC was significantly increased after exercise. To identify potential factors that could be responsible for this effect, we also analysed the semiquantitative serum concentration of 120 cytokines. Of these factors brain-derived neurotrophic factor, cutaneous T-cell-attracting chemokine, epidermal growth factor receptor, glucocorticoid-induced tumour necrosis factor receptor ligand, growth-regulated oncogene-α, interleukin (IL)1a, IL6, IL8, IL15, pulmonary and activation-regulated chemokine and soluble tumour necrosis factor receptor II showed a significant increase whereas migration inhibitory factor howed a decrease in concentration after exercise. Conclusions: IL6 is known to stimulate migration in MSC. It is recognised that contracting skeletal muscles synthesise and release IL6 into the systemic circulation in response to exercise. We therefore hypothesise that there is a direct relationship between exercise, IL6 release and stem cell recruitment.