Miracle-dz/UniFAR-FTUs huggingface dataset:
The Modified Technology Acceptance Model for Private Clinical Physicians: A Case Study in Malaysia, Penang

Abstrast Malaysia’s private clinic is wealth creator. To enhance its sustainable future, healthcare Information Technology (IT) change is inevitable. However, its’ IT acceptance is limited. The past literatures showed physicians have different technology acceptance decision as compare to common users. Hence, understanding the physicians’ technology acceptance is critical for technology management success. This study aims to gauge the factors influence technology acceptance decision among the physicians in Malaysia, Penang private clinics. Due to different trait of physicians, a modified Technology Acceptance Model has been proposed with seven independent variables: physician’s attitude, perceived usefulness, perceived ease of use, IT vendor support, cost factor, training and education and social influence. Questionnaire was distributed to 350 registered private clinics under Penang Medical Practitioner Society. Total 189 questionnaires were returned and useable. Result of multiple regression analysis showed all the independent variables have a significant relationship with the physician’s behavioral intention of IT usage. The proposed model fitness is confirmed with coefficient of determination (R²) of 90.8%. The proposed model provides a platform to enhance understanding and direction to conceptualize the clinical physician’s technology acceptance.
Fast energy evaluation of embedded applications for many-core systems

The growing concerns of energy efficiency and performance scalability motivate research in the area of many-core embedded systems. The software development of such systems plays an important role on the system performance, while accounting for a significant part of the total energy consumption. Thus, it becomes imperative to consider the software energy consumption at early stages of the software development. This paper proposes an instruction-driven energy analysis approach that provides an accurate and practical way of evaluating software energy cost at the speed of up to 1.8 MIPS. Results show that the accuracy of our approach varies from 0.06% to 8.05% when compared to a gate-level implementation.
The Ambiguous Construction of Nondominant Masculinity: Configuring the “New” Man through Narratives of Choice, Involved Fatherhood, and Gender Equality

This article explores the development of gender equality-oriented (heterosexual) masculinity discussing the challenges of constructing nondominant masculine identities in the context of the Danish welfare state. Combining narrative methods with the theoretical framework of masculinity as cultural repertoire, the article offers a qualitative study examining how three Danish men construct (gender) identity in relation to being the partners of career-oriented and high-achieving women. Analyzing the men’s narrative negotiations of power, gender, and self, the article identifies three central narratives produced by the men to render themselves and their family arrangements intelligible and desirable. Considering how the narratives of (1) choice, (2) involved fatherhood, and (3) gender equality work as strategies to negotiate and reconstruct the meaning of compliance and autonomy, I delineate and discuss how traditional notions of what it means to be a man are simultaneously preserved and destabilized. Thus, the article demonstrates that, while nurturing practices and the loss of traditional male breadwinner authority can be positively reconstituted within the Nordic ideals of intensive parenting and gender equality, a fear of male subordination still seems to affect the construction of masculine selves even among gender equality–oriented “new” men.
Insulin and Metformin Regulate Circulating and Adipose Tissue Chemerin

OBJECTIVE To assess chemerin levels and regulation in sera and adipose tissue from women with polycystic ovary syndrome (PCOS) and matched control subjects. RESEARCH DESIGN AND METHODS Real-time RT-PCR and Western blotting were used to assess mRNA and protein expression of chemerin. Serum chemerin was measured by enzyme-linked immunosorbent assay. We investigated the in vivo effects of insulin on serum chemerin levels via a prolonged insulin-glucose infusion. Ex vivo effects of insulin, metformin, and steroid hormones on adipose tissue chemerin protein production and secretion into conditioned media were assessed by Western blotting and enzyme-linked immunosorbent assay, respectively. RESULTS Serum chemerin, subcutaneous, and omental adipose tissue chemerin were significantly higher in women with PCOS (n = 14; P < 0.05, P < 0.01). Hyperinsulinemic induction in human subjects significantly increased serum chemerin levels (n = 6; P < 0.05, P < 0.01). In adipose tissue explants, insulin significantly increased (n = 6; P < 0.05, P < 0.01) whereas metformin significantly decreased (n = 6; P < 0.05, P < 0.01) chemerin protein production and secretion into conditioned media, respectively. After 6 months of metformin treatment, there was a significant decrease in serum chemerin (n = 21; P < 0.01). Importantly, changes in homeostasis model assessment–insulin resistance were predictive of changes in serum chemerin (P = 0.046). CONCLUSIONS Serum and adipose tissue chemerin levels are increased in women with PCOS and are upregulated by insulin. Metformin treatment decreases serum chemerin in these women.
Young and restless: validation of the Mind-Wandering Questionnaire (MWQ) reveals disruptive impact of mind-wandering for youth

Mind-wandering is the focus of extensive investigation, yet until recently there has been no validated scale to directly measure trait levels of task-unrelated thought. Scales commonly used to assess mind-wandering lack face validity, measuring related constructs such as daydreaming or behavioral errors. Here we report four studies validating a Mind-Wandering Questionnaire (MWQ) across college, high school, and middle school samples. The 5-item scale showed high internal consistency, as well as convergent validity with existing measures of mind-wandering and related constructs. Trait levels of mind-wandering, as measured by the MWQ, were correlated with task-unrelated thought measured by thought sampling during a test of reading comprehension. In both middle school and high school samples, mind-wandering during testing was associated with worse reading comprehension. By contrast, elevated trait levels of mind-wandering predicted worse mood, less life-satisfaction, greater stress, and lower self-esteem. By extending the use of thought sampling to measure mind-wandering among adolescents, our findings also validate the use of this methodology with younger populations. Both the MWQ and thought sampling indicate that mind-wandering is a pervasive—and problematic—influence on the performance and well-being of adolescents.
A Qualitative Examination of the Self-Medicating Hypothesis Among Female Juvenile Offenders

Substance misuse among criminally delinquent youth has typically been described as a concurrent part of their participation in risky and delinquent behavior. Using Khantzian’s self-medication hypothesis, this article presents an alternative view by presenting qualitative data which suggests that substance misuse for female juvenile offenders may serve as self-medication for mental health problems stemming from early trauma, often at the hands of their families. Based on the narratives of 30 female juvenile offenders, this article examines the lived experiences of girls with childhood trauma and substance misuse, followed by arrest and incarceration. The paper concludes with recommendations for juvenile justice and child welfare practitioners.
La percepción de los estilos de crianza y su relación con las autopercepciones de los niños de Buenos Aires: Diferencias en función del género

The aim of this work was to study the influence of perceived parenting styles in children's self-perceptions considering differences by gender. The Self-Perception Profile for Children (SPPC) and the Argentine Scale of the Perception of the Relationship with Parents was administered to a sample of 98 children of both genders (males 43.90 %, mean = 9.86 years, SD = 1.28) of Buenos Aires (Argentina). We found that the perception of the relationships with parents predicted the level of girls’ self-perceptions in all the assessed domains (physical/social, academic/behavioral, and global self-esteem) while only the acceptance perceived in the relationship with the mother predicted boys’ self-perceptions in the physical/social domain.
A modified differential evolution algorithm with self-adaptive control parameters

Parameters setting is an important problem of evolution algorithms, include differential evolution algorithm. It has an effect on the performance of evolution algorithms. Although there is only three control parameters in differential evolution (DE) algorithm, the parameters setting is also a difficult problem. Self-adaptation is highly beneficial for adjusting the control parameters, especially when done without any user interaction. This paper presents differential evolution algorithm, called (AdaptDE), which use self-adaptive mechanisms applied to the control parameters. It can get the optimal control parameters for different optimization problem without user interaction. Experimental results indicate that AdaptDE algorithm is efficient and feasible. It is superior to jDE algorithm and FADE algorithm on the quality of solution.
Sequent Calculi for the classical fragment of Bochvar and Halldén's Nonsense Logics

In this paper sequent calculi for the classical fragment (that is, the conjunction-disjunction-implication-negation fragment) of the nonsense logics B3, introduced by Bochvar, and H3, introduced by Halld\'en, are presented. These calculi are obtained by restricting in an appropriate way the application of the rules of a sequent calculus for classical propositional logic CPL. The nice symmetry between the provisos in the rules reveal the semantical relationship between these logics. The Soundness and Completeness theorems for both calculi are obtained, as well as the respective Cut elimination theorems.
Origin of X‐ray emission from transient black hole candidates in quiescence

We report results from a systematic study of X-ray emission from black hole transients in quiescence. In this state, mass accretion is thought to follow the geometry of an outer optically thick, geometrically thin disc and an inner optically thin, geometrically thick radiatively inefficient accretion flow (RIAF). The inner flow is likely also coupled to the jets near the black hole that are often seen in such systems. The goal of the study is to see whether the X-ray emission in the quiescent state is mainly powered by the accretion flow or by the jets. Using data from deep XMM-Newton observations of selected black hole transients, we have found that the quiescent X-ray spectra are, to a high precision, of power-law shape in the cases of GRO J1655-40 and V404 Cyg. Such spectra deviate significantly from the expected X-ray spectrum of the RIAF at very low-accretion rates. On the other hand, they can naturally be explained by emission from the jets, if the emitting electrons follow a power-law spectral distribution (as is often assumed). The situation remains ambiguous in the case of XTE J1550-564, due to the relatively poorer quality of the data. We discuss the implication of the results.
A Super-Alfvénic Model of Dark Clouds

Supersonic random motions are observed in dark clouds and are traditionally interpreted as Alfvén waves, but the possibility that these motions are super-Alfvénic has not been ruled out. In this work we report the results of numerical experiments in two opposite regimes: ℳA ~ 1 and ℳA ≫ 1, where ℳA is the initial Alfvénic Mach number—the ratio of the rms velocity to the Alfvén speed. Our results show that models with ℳA ≫ 1 are consistent with the observed properties of molecular clouds that we have tested (statistics of extinction measurements, distribution of integrated antenna temperature, Zeeman-splitting measurements of magnetic field strength, line width versus integrated antenna temperature of molecular emission-line spectra, statistical B-n relation, and scatter in that relation), while models withℳA ~ 1 have properties that are in conflict with the observations. We find that both the density and the magnetic field in molecular clouds may be very intermittent. The statistical distributions of the magnetic field and gas density are related by a power law, with an index that decreases with time in experiments with decaying turbulence. After about one dynamical time it stabilizes at B ∝ n0.4. Magnetically dominated cores form early in the evolution, while later on the intermittency in the density field wins out, and also cores with a weak field can be generated by mass accretion along magnetic field lines.
Numerical Simulation of RF Noise in Si Devices

The workhorse of today's TCAD is the drift-diffusion (DD) model, which in the special formulation of the impedance field method has been used for a long time for noise calculation, but there has been much debate over its noise source. The derivation of the DD noise model from the Langevin-type Boltzmann equation (LBE) is discussed in detail and it is shown that the DD noise source should be local in the real space, white and given by the power spectral density (PSD) of the velocity fluctuations at zero frequency calculated under homogeneous bulk conditions in analogy to the mobility. The white noise source and frequency independent mobility of the DD model reflect the neglect of certain acceleration terms in the LBE. By comparison of solutions of the LBE with and without these terms it is found that the DD model works well up to frequencies of about 100 GHz in silicon devices. Comparison of solutions of the LBE and DD model for different definitions of the noise source shows that the best device results are obtained with the PSD of the velocity fluctuations calculated under bulk conditions. Use of the Einstein relation to calculate the noise source for nonequilibrium, as is often done, leads to an underestimation of noise. While the DD model delivers good results in sub-micron devices, it fails in very small devices resulting in spurious super shot noise. Based on the LBE it is found that excess noise in devices is mostly due to scattering of cold or warm electrons, whereas hot electrons contribute little in the absence of electron-hole pair generation
The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

The precise regulation of S-phase–specific genes is critical for cell proliferation. How the repressive chromatin configuration mediated by the retinoblastoma protein and repressor E2F factors changes at the G1/S transition to allow transcription activation is unclear. Here we show ChIP-on-chip studies that reveal that the chromatin remodeller CHD8 binds ∼2000 transcriptionally active promoters. The spectrum of CHD8 target genes was enriched in E2F-dependent genes. We found that CHD8 binds E2F-dependent promoters at the G1/S transition but not in quiescent cells. Consistently, CHD8 was required for G1/S-specific expression of these genes and for cell cycle re-entry on serum stimulation of quiescent cells. We also show that CHD8 interacts with E2F1 and, importantly, loading of E2F1 and E2F3, but not E2F4, onto S-specific promoters, requires CHD8. However, CHD8 recruiting is independent of these factors. Recruiting of MLL histone methyltransferase complexes to S-specific promoters was also severely impaired in the absence of CHD8. Furthermore, depletion of CHD8 abolished E2F1 overexpression-dependent S-phase stimulation of serum-starved cells, highlighting the essential role of CHD8 in E2F-dependent transcription activation.
Neural plasticity of mushroom body-extrinsic neurons in the honeybee brain

SUMMARY Central interneurons exiting the alpha lobe of the mushroom bodies were studied with respect to their plasticity by electrically stimulating their presynaptic inputs, the Kenyon cells. Special attention was given to the analysis of a single, identified neuron, the PE1. Three stimulation protocols were tested: double pulses, tetanus (100 Hz for 1 s), and tetanus paired with intracellular de- or hyper-polarization of the recorded cell. Double-pulse stimulations revealed short-term facilitation and depression, tuning the responses of these interneurons to frequencies in the range of 20–40 Hz. The tetanus may lead to augmentation of responses to test stimuli lasting for several minutes, or to depression followed by augmentation. Associative long-term potentiation (LTP) was induced in the PE1 neuron by pairing a presynaptic tetanus with depolarization. This is the first time that associative LTP has been found in an interneuron of the insect nervous system. These data are discussed in the context of spike tuning in the output of the mushroom body, and the potential role of associative LTP in olfactory learning. It is concluded that the honeybee mushroom body output neurons are likely to contribute to the formation of olfactory memory.
Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium

Cytomegalovirus (CMV) infection elicits a very strong and sustained intravascular T cell immune response which may contribute towards development of accelerated immune senescence and vascular disease in older people. Virus-specific CD8+ T cell responses have been investigated extensively through the use of HLA-peptide tetramers but much less is known regarding CMV-specific CD4+ T cells. We used a range of HLA class II-peptide tetramers to investigate the phenotypic and transcriptional profile of CMV-specific CD4+ T cells within healthy donors. We show that such cells comprise an average of 0.45% of the CD4+ T cell pool and can reach up to 24% in some individuals (range 0.01–24%). CMV-specific CD4+ T cells display a highly differentiated effector memory phenotype and express a range of cytokines, dominated by dual TNF-α and IFN-γ expression, although substantial populations which express IL-4 were seen in some donors. Microarray analysis and phenotypic expression revealed a profile of unique features. These include the expression of CX3CR1, which would direct cells towards fractalkine on activated endothelium, and the β2-adrenergic receptor, which could permit rapid response to stress. CMV-specific CD4+ T cells display an intense cytotoxic profile with high level expression of granzyme B and perforin, a pattern which increases further during aging. In addition CMV-specific CD4+ T cells demonstrate strong cytotoxic activity against antigen-loaded target cells when isolated directly ex vivo. PD-1 expression is present on 47% of cells but both the intensity and distribution of the inhibitory receptor is reduced in older people. These findings reveal the marked accumulation and unique phenotype of CMV-specific CD4+ T cells and indicate how such T cells may contribute to the vascular complications associated with CMV in older people.
Extension of Gutenberg‐Richter distribution to MW −1.3, no lower limit in sight

With twelve years of seismic data from TauTona Gold Mine, South Africa, we show that mining‐induced earthquakes follow the Gutenberg‐Richter relation with no scale break down to the completeness level of the catalog, at moment magnitude MW −1.3. Events recorded during relatively quiet hours in 2006 indicate that catalog detection limitations, not earthquake source physics, controlled the previously reported minimum magnitude in this mine. Within the Natural Earthquake Laboratory in South African Mines (NELSAM) experiment's dense seismic array, earthquakes that exhibit shear failure at magnitudes as small as MW −3.9 are observed, but we find no evidence that MW −3.9 represents the minimum magnitude. In contrast to previous work, our results imply small nucleation zones and that earthquake processes in the mine can readily be scaled to those in either laboratory experiments or natural faults.
CLINICAL COMMENTS

These can take the form of case studies or brief reports of research. The purpose of all clinical comments is to illustrate something concisely. There must be a clear focus on a central theme. Clinical comments should be under four (double spaced) pages, and minimize tables and references. The title should appear on top. At the end of the text, include name(s) of author(s), highest earned degree(s), and institutional affiliation (or city if in private practice). Please submit four copies with a self-addressed, stamped envelope.
Is Inhibition of Return Modulated by Involuntary Orienting of Spatial Attention: An ERP Study

Inhibition of return (IOR) is a mechanism that indicates individuals’ faster responses or higher accuracy to targets appearing in the novel location relative to the cued location. According to the “reorienting hypothesis,” disengagement from the cued location is necessary for the generation of IOR. However, more and more studies have questioned this theory because of dissociation between voluntary or involuntary spatial orienting and the IOR effect. To further explore the “reorienting hypothesis” of IOR, the present experiment employed an atypical cue-target paradigm which combined a spatially non-predictive peripheral cue that was presumed to trigger IOR with a spatially non-predictive central cue that was used to reflexively trigger a shift of attention. The results showed that a significant IOR effect did not interact with automatic spatial orienting as measured in mean RTs and accuracy as well as the Nd component. These findings suggested that the IOR effect triggered by peripheral cue was independent of automatic orienting generated by a central cue. Therefore, the present study provided evidence from location task and neural aspects, which again challenged the “reorienting hypothesis” of IOR.
Single-Case Analysis to Determine Reasons for Failure of Behavioral Treatment via Telehealth

Functional communication training (FCT) is a widely used and effective function-based treatment for problem behavior. The purpose of this article is to present two cases in which FCT was unsuccessful in reducing the occurrence of problem behavior displayed by two young children with an autism spectrum disorder. Both children received the same functional analysis plus FCT treatment package via telehealth that had proven to be highly successful for the other participants. The FCT package was conducted within tightly controlled single-case designs for each participant, which permitted subsequent analyses to determine why FCT was unsuccessful. These analyses suggested distinct reasons for the treatment failure for each child. Although the negative results of treatment appeared to be similar for both children, the specific reasons for treatment failure were highly individualistic and identifiable via the single-case analyses conducted. We present findings from both our initial and subsequent analyses and discuss the implications.
A low-complexity 3D spatio-temporal FIR filter for enhancing linear trajectory signals

A low-complexity 3D FIR filter is proposed for selectively enhancing severely corrupted linear trajectory spatio-temporal signals. The proposed 3D FIR filter is separable and consists of a 3D spatio-temporal wide-angle FIR cone filter between two 2D spatial variable-shift filters. Low complexity of the 3D spatio-temporal wide-angle FIR cone filter is achieved by exploiting the spatial-symmetry of the passband and by employing maximal decimation in the temporal dimension. Compared to existing techniques, the proposed 3D FIR filter provides significant reduction of the computational complexity for similar SINR improvement.