Miracle-dz/UniFAR-FTUs huggingface dataset:
Do Multiple Forms of Social Capital Mediate the Relationship Between Parental Violence and Children’s Maladaptive Behaviors?

Many things can harm children’s well-being. Among them, exposure to parental violence makes children vulnerable and often leads to aggression and/or depression. However, not all children who have suffered parental violence show aggressive behavior or depressive mood. Social capital, defined as resources accruing from interpersonal relationships, was proposed to significantly mediate the relationships among adverse experiences and their negative impacts. In previous studies, social capital accrued from parents played a positive role for children in violent situations, but children exposed to parental violence need alternative sources of social capital. This study targeted fourth-grade Korean children and aimed to identify and test the role of various forms of social capital to help children overcome negative consequences from parental violence. Siblings, friends, teachers, neighbors, and online acquaintances were sources of social capital, and the results showed that social capital from siblings, teachers, neighbors, or online acquaintances mediated in the relationships between parental violence and aggressive behavior. In addition, social capital from siblings and online acquaintances mediated in the relationships between parental violence and depressive mood. The findings have implications in terms of intervention. It is suggested that multiple forms of social capital from children’s immediate environments are helpful in their adaptation from exposure to parental violence, and thus, relationship-based interventions are recommended.
Statistical Errors in Remote Passive Wireless SAW Sensing Employing Phase Differences

Passive remote wireless sensing employing properties of the surface acoustic wave (SAW) has gained currency during a couple of decades to measure different physical quantities such as temperature, force (pressure, torque, and stress), velocity, direction of motion, etc. with a resolution of about 1% [1]. The basic principle utilized in such a technique combines advantages of the precise piezoelectric sensors [2, 3, 4], high SAW sensitivity to the environment, passive (without a power supply) operation, and wireless communication between the sensor element and the reader (interrogator). Several passive wireless SAW devices have been manufactured to measure temperature [1], identify the railway vehicle at high speed [5], and pressure and torque [6]. The information bearer in such sensors is primarily the time delay of the SAW or the central frequency of the SAW device. Most passive SAW sensors are designed as reflective delay lines with
Environmental Change and Disease Dynamics: Effects of Intensive Forest Management on Puumala Hantavirus Infection in Boreal Bank Vole Populations

Intensive management of Fennoscandian forests has led to a mosaic of woodlands in different stages of maturity. The main rodent host of the zoonotic Puumala hantavirus (PUUV) is the bank vole (Myodes glareolus), a species that can be found in all woodlands and especially mature forests. We investigated the influence of forest age structure on PUUV infection dynamics in bank voles. Over four years, we trapped small mammals twice a year in a forest network of different succession stages in Northern Finland. Our study sites represented four forest age classes from young (4 to 30 years) to mature (over 100 years) forests. We show that PUUV-infected bank voles occurred commonly in all forest age classes, but peaked in mature forests. The probability of an individual bank vole to be PUUV infected was positively related to concurrent host population density. However, when population density was controlled for, a relatively higher infection rate was observed in voles trapped in younger forests. Furthermore, we found evidence of a “dilution effect” in that the infection probability was negatively associated with the simultaneous density of other small mammals during the breeding season. Our results suggest that younger forests created by intensive management can reduce hantaviral load in the environment, but PUUV is common in woodlands of all ages. As such, the Fennoscandian forest landscape represents a significant reservoir and source of hantaviral infection in humans.
Distribution trends of Indonesia's health care resources in the decentralization era

Indonesia has been decentralized since 2001, and we evaluated the distribution trends of physicians, puskesmas (community health centers), hospitals, and hospital beds in 34 provinces in Indonesia for 2000 to 2014. Inequality index of Gini showed improvement of the distribution of physicians and decreased from 0.38 to 0.29. The indices in distributions of hospitals and hospital beds also decreased from 0.26 to 0.17 and from 0.25 to 0.18, respectively. However, the index in the distribution of puskesmas increased from 0.19 to 0.28. We also investigated the legislative transitions of the laws concerning health resources and found the strong affects of compulsory work laws for physicians and the increment of health budget. In the decentralization era, the local governments have some political autonomy for the development of health resources; however, the national government should monitor the nationwide distribution of health resources and advice necessary recommendations to the local governments.
Molecular Basis of Differential B-Pentamer Stability of Shiga Toxins 1 and 2

Escherichia coli strain O157:H7 is a major cause of food poisoning that can result in severe diarrhea and, in some cases, renal failure. The pathogenesis of E. coli O157:H7 is in large part due to the production of Shiga toxin (Stx), an AB5 toxin that consists of a ribosomal RNA-cleaving A-subunit surrounded by a pentamer of receptor-binding B subunits. There are two major isoforms, Stx1 and Stx2, which differ dramatically in potency despite having 57% sequence identity. Animal studies and epidemiological studies show Stx2 is associated with more severe disease. Although the molecular basis of this difference is unknown, data suggest it is associated with the B-subunit. Mass spectrometry studies have suggested differential B-pentamer stability between Stx1 and Stx2. We have examined the relative stability of the B-pentamers in solution. Analytical ultracentrifugation using purified B-subunits demonstrates that Stx2B, the more deadly isoform, shows decreased pentamer stability compared to Stx1B (EC50 = 2.3 µM vs. EC50 = 0.043 µM for Stx1B). X-ray crystal structures of Stx1B and Stx2B identified a glutamine in Stx2 (versus leucine in Stx1) within the otherwise strongly hydrophobic interface between B-subunits. Interchanging these residues switches the stability phenotype of the B-pentamers of Stx1 and Stx2, as demonstrated by analytical ultracentrifugation and circular dichroism. These studies demonstrate a profound difference in stability of the B-pentamers in Stx1 and Stx2, illustrate the mechanistic basis for this differential stability, and provide novel reagents to test the basis for differential pathogenicity of these toxins.
Does Landscape Fragmentation Influence Sex Ratio of Dioecious Plants? A Case Study of Pistacia chinensis in the Thousand-Island Lake Region of China

The Thousand-Island Lake region in Zhejiang Province, China is a highly fragmented landscape with a clear point-in-time of fragmentation as a result of flooding to form the reservoir. Islands in the artificial lake were surveyed to examine how population sex ratio of a dioecious plant specie Pistacia chinensis B. was affected by landscape fragmentation. A natural population on the mainland near the lake was also surveyed for comparison. Population size, sex ratio and diameter at breast height (DBH) of individuals were measured over 2 years. More than 1,500 individuals, distributed in 31 populations, were studied. Soil nitrogen in the different populations was measured to identify the relationship between sex ratio and micro-environmental conditions. In accordance with the results of many other reports on biased sex ratio in relation to environmental gradient, we found that poor soil nitrogen areas fostered male-biased populations. In addition, the degree of sex ratio bias increased with decreasing population size and population connectivity. The biased sex ratios were only found in younger individuals (less than 50 years old) in small populations, while a stable 1∶1 sex ratio was found in the large population on the mainland. We concluded that the effects of landscape fragmentation on the dioecious population sex ratio were mainly achieved in relation to changing soil nitrogen conditions in patches and pollen limitation within and among populations. Large populations could maintain a more suitable environment in terms of nutrient conditions and pollen flow, subsequently maintaining a stable sex ratio in dioecious plant populations. Both micro-environmental factors and spatial structure should be considered in fragmented landscape for the conservation of dioecious plant species.
Risk of Dying from Cancer by Socio-demographic Indicators in the Slovak Republic.

AIM Cancer mortality distribution was investigated by detailed neoplasms groups, age, sex, marital status of deceased, and regions in the Slovak Republic, and examined how these determinants influence the odds of dying due to cancer. METHODS A retrospective analysis of cancer mortality statistics registered in the Slovak Republic during the years 1996-2014. For this time period, data was available only on the underlying subgroups of cancer deaths, place of death, age, year, sex, and marital status. Binary logistic regression was applied for odds of dying calculation influenced by these socio-demographic factors. RESULTS The most common are deaths from malignant neoplasms of digestive organs in males as well as females. The biggest difference among both genders is recognized in malignant neoplasms of lip, oral cavity and pharynx, where deaths among males are on average 7.9 times higher in comparison to females. As for place of death the Bratislava region reports the highest level of cancer mortality stated at 25.22% of all deaths, on the contrary the Banská Bystrica region reports only 21.40% of all deaths. Age has a negative influence on odds of dying due to neoplasms compared to all other causes of death by 1.7%. In all regions compared to the reference Bratislava region, the odds of dying from neoplasms are lower. Being female diminishes the odds of dying due to neoplasms by 25.7% compared to males. Yearly the relative ratio of dying from neoplasms increases with respect to all other causes of death. When single people are set as the reference category, the relation of the probability of death from cancer to the probability of death due to other causes of death is higher for married, divorced and widowed persons. CONCLUSIONS The results should be taken into account when comparing risk of dying due to cancer among people with the mentioned sociodemographic characteristics. Health policy makers should consider place of death and cancer types while planning hospital care units.
Does Patient Blood Glucose Monitoring Improve Diabetes Control?

OBJECTIVE The purpose of this systematic review was 2-fold: first, to perform a comprehensive review of relevant studies on the impact of self-monitoring of blood glucose (SMBG) on HbA1c levels for patients with type 2 diabetes mellitus and, second, to explore mediators and moderators within a self-regulation framework. DATA SOURCES Five databases-Medline, PsychInfo, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing & Allied Health Literature (CINAHL)-were searched. STUDY SELECTION Cross-sectional, longitudinal, and randomized control trials from 1990 to 2006, which included patients with type 2 diabetes not on insulin, were reviewed. In total, 6,769 studies were screened for inclusion, 89 were retrieved for detailed analysis, and 29 met criteria for inclusion in the review. DATA EXTRACTION Data on the impact of SMBG on HbA1c, potential mediators and moderators, study design and participants, and limitations of each study were retrieved. DATA SYNTHESIS Twenty-nine studies were included in this review: 9 cross-sectional studies, 9 longitudinal studies, and 11 randomized controlled trials. Evidence from the cross-sectional and longitudinal studies was inconclusive. Evidence from randomized controlled trials suggests that SMBG may lead to improvements in glucose control. Very few studies examined potential mediators or moderators of SMBG on HbA1c levels. CONCLUSIONS SMBG may be effective in controlling blood glucose for patients with type 2 diabetes. There is a need for studies that implement all the components of the process for self-regulation of SMBG to assess whether patient use of SMBG will improve HbA1c levels.
Body odour disgust sensitivity predicts authoritarian attitudes

Authoritarianism has resurfaced as a research topic in political psychology, as it appears relevant to explain current political trends. Authoritarian attitudes have been consistently linked to feelings of disgust, an emotion that is thought to have evolved to protect the organism from contamination. We hypothesized that body odour disgust sensitivity (BODS) might be associated with authoritarianism, as chemo-signalling is a primitive system for regulating interpersonal contact and disease avoidance, which are key features also in authoritarianism. We used well-validated scales for measuring BODS, authoritarianism and related constructs. Across two studies, we found that BODS is positively related to authoritarianism. In a third study, we showed a positive association between BODS scores and support for Donald Trump, who, at the time of data collection, was a presidential candidate with an agenda described as resonating with authoritarian attitudes. Authoritarianism fully explained the positive association between BODS and support for Donald Trump. Our findings highlight body odour disgust as a new and promising domain in political psychology research. Authoritarianism and BODS might be part of the same disease avoidance framework, and our results contribute to the growing evidence that contemporary social attitudes might be rooted in basic sensory functions.
Internet Traffic Classification Using Machine Learning: A Token-based Approach

Due to the increasing unreliability of traditional port-based methods, Internet traffic classification has attracted a lot of research efforts in recent years. Quite a lot of previous papers have focused on using statistical characteristics as discriminators and applying machine learning techniques to classify the traffic flows. In this paper, we propose a novel machine learning based approach where the features are extracted from packet payload instead of flow statistics. Specifically, every flow is represented by a feature vector, in which each item indicates the occurrence of a particular token, i.e., a common substring, in the payload. We have applied various machine learning algorithms to evaluate the idea and used different feature selection schemes to identify the critical tokens. Experimental result based on a real-world traffic data set shows that the approach can achieve high accuracy with low overhead.
Effect of pollution on the fluctuating asymmetry in the grass goby Zosterisessor ophiocephalus Pallas, 1811 as contamination indicator of Eastern Tunisia.

In this work, we study the effect of habitat degradation and environmental stress on fluctuating asymmetry, a morphological parameter of the grass goby Zosterisessor ophiocephalus Pallas, 1811, sampled from eastern coasts of Tunisia. Ninety-six specimens of Zosterisessor ophiocephalus were collected during SeptemberNovember 2012 from two sites: one polluted (Khniss) and one control (Chebba) in eastern littoral zone of Tunisia. Six bilateral metric and two meristic characters were used to assess fluctuating asymmetry. Statistical analysis showed that assessed asymmetries are fluctuating. FA of sub-orbital and post-orbital distances, orbital diameter, and pelvic and pectoral fin lengths, are higher in polluted site compared to control. Chemical and organic pollution from sewage discharge seems to be responsible for this high FA. Many actions should be taken to save the khniss ecosystem: control the quality of waste water, push the current treatment of certain plants to tertiary treatment, act on the current discharge to improve the conditions of his release in sea and move rejection seaward to a minimum depth of 15 m to prevent pollution reaching the coast and for better dilution and dispersion of pollutants
Efficient delivery of therapeutic siRNA into glioblastoma cells using multifunctional dendrimer-entrapped gold nanoparticles.

AIM To synthesize the arginine-glycine-aspartic (RGD) functionalized dendrimer-entrapped gold nanoparticles (Au DENPs) for siRNA delivery to induce gene silencing of cancer cells in vitro and in vivo. MATERIALS & METHODS Au DENPs modified with RGD peptide via a polyethylene glycol spacer were used as a vector of two distinct small interfering RNAs (siRNAs) (VEGFvascular endothelial growth factor siRNA and B-cell lymphoma/leukemia-2 siRNA), and the physicochemical properties, cytocompatibility and transfection efficiency of Au DENP/siRNA polyplexes were characterized. RESULTS The Au DENP/siRNA polyplexes with good cytocompatibility and highly efficient transfection capacity can be used for the transfection of siRNAs. CONCLUSION The developed functional RGD-modified Au DENPs may be used for efficient gene therapy of different types of cancer.
Transitions in sex determination and sex chromosomes across vertebrate species

Despite the prevalence of sexual reproduction across eukaryotes, there is a remarkable diversity of sex‐determination mechanisms. The underlying causes of this diversity remain unclear, and it is unknown whether there are convergent trends in the directionality of turnover in sex‐determination mechanisms. We used the recently assembled Tree of Sex database to assess patterns in the evolution of sex‐determination systems in the remarkably diverse vertebrate clades of teleost fish, squamate reptiles and amphibians. Contrary to theoretical predictions, we find no evidence that the evolution of separate sexes is irreversible, as transitions from separate sexes to hermaphroditism occur at higher rates than the reverse in fish. We also find that transitions from environmental sex determination to genetic sex determination occur at higher rates than the reverse in both squamates and fish, suggesting that genetic sex determination is more stable. However, our data are not consistent with the hypothesis that heteromorphic sex chromosomes are an “evolutionary trap. ” Rather, we find similar transition rates between homomorphic and heteromorphic sex chromosomes in both fish and amphibians, and to environmental sex determination from heteromorphic vs. homomorphic sex chromosome systems in fish. Finally, we find that transitions between male and female heterogamety occur at similar rates in amphibians and squamates, while transitions to male heterogamety occur at higher rates in fish. Together, these results provide the most comprehensive view to date of the evolution of vertebrate sex determination in a phylogenetic context, providing new insight into long‐standing questions about the evolution of sexual reproduction.
Divergent Changes in Plant Community Composition under 3-Decade Grazing Exclusion in Continental Steppe

An understanding of the factors controlling plant community composition will allow improved prediction of the responses of plant communities to natural and anthropogenic environmental change. Using monitoring data from 1980 to 2009, we quantified the changes in community composition in Leymus chinensis and Stipa grandis dominated grasslands in Inner Mongolia under long-term grazing-exclusion and free-grazing conditions, respectively. We demonstrated that the practice of long-term grazing exclusion has significant effects on the heterogeneity, the dominant species, and the community composition in the two grasslands. The community composition of L. chinensis and S. grandis grasslands exhibited directional changes with time under long-term grazing exclusion. Under free grazing, the L. chinensis community changed directionally with time, but the pattern of change was stochastic in the S. grandis community. We attributed the divergent responses to long-term grazing exclusion in the S. grandis and L. chinensis grasslands to litter accumulation and changes in the microenvironment after grazing exclusion, which collectively altered the growth and regeneration of the dominant species. The changes in the grazed grasslands were primarily determined by the selective feeding of sheep during long-term heavy grazing. Overall, the responses of the community composition of the Inner Mongolian grasslands to long-term grazing exclusion and heavy grazing were divergent, and depended primarily on the grassland type. Our findings provide new insights into the role of grazing in the maintenance of community structure and function and therefore have important implications for grassland management.
Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma

Objective To investigate the expression of androgen receptor (AR) and its correlation with disease status and survival outcome in uterine leiomyosarcoma with other hormone receptors. Methods The medical records and paraffin blocks of 42 patients were reviewed. The immunohistochemical expression of AR, estrogen receptor (ER), progesterone receptor (PR), gonadotropin releasing hormone (GnRH), and cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1) were assessed using tissue microarray. Results In total, AR expression was observed in 11 patients (26.2%). International Federation of Gynecology and Obstetrics (FIGO) stage and AR were independent factors for disease-free survival (DFS) in multivariate regression analysis (odds ratio [OR]=5.8; 95% confidence interval [CI]=1.2–28.4 and OR=0.2; 95% CI=0.05–0.90; p=0.029 and 0.032, respectively). There were no deaths in the AR expression group, whereas the 5-year overall survival (OS) was 54.8% in the no expression group (p=0.014). Co-expression of ER and/or PR with AR was associated with significantly better 5-year DFS and OS than those with negative AR (72.7% vs. 28.6% and 100% vs. 64.3%; p=0.020 and 0.036, respectively). AR may be an independent prognostic marker regardless of ER/PR. Conclusion AR can be a potential prognostic biomarker in uterine leiomyosarcoma.
Salient Object Detection via Adaptive Region Merging

Most existing salient object detection algorithms commonly employed segmentation techniques to eliminate background noise and reduce computation by treating each segment as a processing unit. However, individual small segments provide little information about global contents. Such schemes have limited capability on modeling global perceptual phenomena. In this paper, a novel salient object detection algorithm is proposed based on region merging. An adaptive-based merging scheme is developed to reassemble regions based on their color dissimilarities. The merging strategy can be described as that a region R is merged with its adjacent region Q if Q has the lowest dissimilarity with Q among all Q’s adjacent regions. To guide the merging process, superpixels that located at the boundary of the image are treated as the seeds. However, it is possible for a boundary in the input image to be occupied by the foreground object. To avoid this case, we optimize the boundary influences by locating and eliminating erroneous boundaries before the region merging. We show that even though three simple region saliency measurements are adopted for each region, encouraging performance can be obtained. Experiments on four benchmark datasets including MSRA-B, SOD, SED and iCoSeg show the proposed method results in uniform object enhancement and achieve state-of-the-art performance by comparing with nine existing methods.