Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental and Numerical Study on Enhanced Heat Transfer of Solid-Liquid PCM by Ultrasonic Wave

The present study is investigated the causes of enhanced heat transfer during the melting process of solid-liquid PCM (Phase Change Material) using an ultrasonic vibration. Paraffin (noctadecane) was selected as a PCM and experimental studies were performed as following. Heat transfer coefficient and enhancement ratio of heat transfer was measured, acoustic streaming induced by ultrasonic waves observed using a PIV (Particle Image Velocimetry) and thermally oscillating flow phenomenon observed using an infrared thermal camera during the melting process. For the numerical study, a coupled FE-BEM (Finite Element-Boundary Element Method) was applied to investigate acoustic pressure occurred by acoustic streaming in a medium. And then, the profiles of pressure variation compared with the enhancement ratio of heat transfer. The results of this study revealed that ultrasonic vibrations accompanied the effects like acoustic streaming and thermally oscillating flow. Such effects are a prime mechanism in the overall melting process when ultrasonic vibrations are applied. Also, as the acoustic pressure occurred by acoustic streaming increases, the higher enhancement ratio of heat transfer is obtained.
Flexible and scalable storage management for data-intensive stream processing

Data Stream Management Systems (DSMS) operate under strict performance requirements. Key to meeting such requirements is to efficiently handle time-critical tasks such as managing internal states of continuous query operators, traffic on the queues between operators, as well as providing storage support for shared computation and archived data. In this paper, we introduce a general purpose storage management framework for DSMSs that performs these tasks based on a clean, loosely-coupled, and flexible system design that also facilitates performance optimization. An important contribution of the framework is that, in analogy to buffer management techniques in relational database systems, it uses information about the access patterns of streaming applications to tune and customize the performance of the storage manager. In the paper, we first analyze typical application requirements at different granularities in order to identify important tunable parameters and their corresponding values. Based on these parameters, we define a general-purpose storage management interface. Using the interface, a developer can use our SMS (Storage Manager for Streams) to generate a customized storage manager for streaming applications. We explore the performance and potential of SMS through a set of experiments using the Linear Road benchmark.
Frequent Directions: Simple and Deterministic Matrix Sketching

We describe a new algorithm called FrequentDirections for deterministic matrix sketching in the row-update model. The algorithm is presented an arbitrary input matrix A \in \mathbb{R}^{n \times d} one row at a time. It performs O(d\ell) operations per row and maintains a sketch matrix B \in \mathbb{R}^{\ell \times d} such that for any k < \ell, \|A^TA - B^TB \|_2 \leq \|A - A_k\|_F^2 / (\ell-k) {\;and\;} \|A - \pi_{B_k}(A)\|_F^2 \leq (1 + \frac{k}{\ell-k}) \|A-A_k\|_F^2. Here, A_k stands for the minimizer of \|A - A_k\|_F over all rank k matrices (similarly for B_k) and \pi_{B_k}(A) is the rank k matrix resulting from projecting A on the row span of B_k. We show that both of these bounds are the best possible for the space allowed. The summary is mergeable and hence trivially parallelizable. Moreover, FrequentDirections outperforms exemplar implementations of existing streaming algorithms in the space-error tradeoff. This paper combines, simplifies, and extends the results of Liberty [Proceedings of the 1.
Optimality of size-degree tradeoffs for polynomial calculus

There are methods to turn short refutations in <i>polynomial calculus</i> (Pc) and <i>polynomial calculus with resolution</i> (Pcr) into refutations of low degree. Bonet and Galesi [1999, 2003] asked if such size-degree tradeoffs for Pc [Clegg et al. 1996; Impagliazzo et al. 1999] and Pcr [Alekhnovich et al. 2004] are optimal. We answer this question by showing a polynomial encoding of the <i>graph ordering principle</i> on <i>m</i> variables which requires Pc and Pcr refutations of degree Ω(&sqrt; <i>m</i>). Tradeoff optimality follows from our result and from the short refutations of the graph ordering principle in Bonet and Galesi [1999, 2001]. We then introduce the algebraic proof system Pcr<i><sub>k</sub></i> which combines together polynomial calculus and <i>k-DNF resolution</i> (Res<i><sub>k</sub></i>). We show a size hierarchy theorem for Pcr<i><sub>k</sub></i>: Pcr<i><sub>k</sub></i> is exponentially separated from Pcr<i><sub>k+1</sub></i>. This follows from the previous degree lower bound and from techniques developed for Res<i><sub>k</sub></i>. Finally we show that random formulas in conjunctive normal form (3-CNF) are hard to refute in Pcr<i><sub>k</sub></i>.
The attention system of the human brain.

Illustration de trois fonctions principales qui sont predominantes dans l'etude de l'intervention de l'attention dans les processus cognitifs: 1) orientation vers des evenements sensoriels; 2) detection des signaux par processus focal; 3) maintenir la vigilance en etat d'alerte
STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites

The yeast cell type regulator MATα (α2) is degraded through two ubiquitylation pathways, one of which has been minimally characterized. We identify two regions in α2 important for this pathway and show that these regions overlap specific binding sites for α2 corepressors, suggesting that α2 degradation is coordinated with its functional status.
Bottom-up Retinotopic Organization Supports Top-down Mental Imagery

Finding a path between locations is a routine task in daily life. Mental navigation is often used to plan a route to a destination that is not visible from the current location. We first used functional magnetic resonance imaging (fMRI) and surface-based averaging methods to find high-level brain regions involved in imagined navigation between locations in a building very familiar to each participant. This revealed a mental navigation network that includes the precuneus, retrosplenial cortex (RSC), parahippocampal place area (PPA), occipital place area (OPA), supplementary motor area (SMA), premotor cortex, and areas along the medial and anterior intraparietal sulcus. We then visualized retinotopic maps in the entire cortex using wide-field, natural scene stimuli in a separate set of fMRI experiments. This revealed five distinct visual streams or ‘fingers’ that extend anteriorly into middle temporal, superior parietal, medial parietal, retrosplenial and ventral occipitotemporal cortex. By using spherical morphing to overlap these two data sets, we showed that the mental navigation network primarily occupies areas that also contain retinotopic maps. Specifically, scene-selective regions RSC, PPA and OPA have a common emphasis on the far periphery of the upper visual field. These results suggest that bottom-up retinotopic organization may help to efficiently encode scene and location information in an eye-centered reference frame for top-down, internally generated mental navigation. This study pushes the border of visual cortex further anterior than was initially expected.
Sulfation of lithocholate as a possible modifier of chenodeoxycholic acid-induced elevations of serum transaminase in patients with gallstones.

Chenodeoxycholic acid (CDC), through its metabolite, lithocholic acid (LC), is hepatotoxic in certain species. The cause of elevations of serum transaminase in 25% of humans ingesting CDC, however, is unknown, but also may be due to LC. Because efficient hepatic sulfation of LC may protect against hepatic injury, the aim of this study was to determine if sulfation of LC might modify CDC-induced elevations of transaminase. Pretreatment sulfation fraction (SF) was estimated in 63 randomly selected patients with gallstones in a double-blind randomized trial of CDC, 750 mg/d, 375 mg/d, or placebo; in 27 of these, SF was repeated at 1 or 2 yr. In four other patients, the SF was measured at 2 yr only. Serum glutamic oxaloacetic transaminase and serum glutamic pyruvic transaminase were determined monthly for 3 mo and then every 3 or 4 mo; an elevation of transaminase was defined as > 150% of the normal upper limit in asymptomatic patients. 10 muCi of (3)H-glyco-LC (sp act 84 mCi/mol) was ingested 10-12 h before fasting duodenal biliary drainage. Bile acids in bile were separated by thin-layer chromatography. The SF was estimated as a percentage of total radioactivity (scintillation counting) in sulfated glyco-LC. The standard deviation for replicate SF determinations (n = 311) was 2.1% The pretreatment SF (mean 60.7+/-1.7 SEM) correlated inversely with age (r = 0.336, P < 0.005) and directly with the obesity index (r = 0.495, P > 0.001), but was independent of sex. The SF, remeasured at 1 or 2 yr, did not change significantly with time or CDC. Among CDC-treated patients, elevations of transaminase occurred in 75% of patients with a SF < 45% vs. 11% with a SF > 45% (P < 0.001). In conclusion, a SF < 45% occurred in patients with gallstones who had a high probability of developing elevated serum transaminase when treated with CDC. Thus, sulfation of lithocholate may modify CDC-induced elevations of serum transaminase.
Phosphorylation of Slx4 by Mec1 and Tel1 Regulates the Single-Strand Annealing Mode of DNA Repair in Budding Yeast

ABSTRACT Budding yeast (Saccharomyces cerevisiae) Slx4 is essential for cell viability in the absence of the Sgs1 helicase and for recovery from DNA damage. Here we report that cells lacking Slx4 have difficulties in completing DNA synthesis during recovery from replisome stalling induced by the DNA alkylating agent methyl methanesulfonate (MMS). Although DNA synthesis restarts during recovery, cells are left with unreplicated gaps in the genome despite an increase in translesion synthesis. In this light, epistasis experiments show that SLX4 interacts with genes involved in error-free bypass of DNA lesions. Slx4 associates physically, in a mutually exclusive manner, with two structure-specific endonucleases, Rad1 and Slx1, but neither of these enzymes is required for Slx4 to promote resistance to MMS. However, Rad1-dependent DNA repair by single-strand annealing (SSA) requires Slx4. Strikingly, phosphorylation of Slx4 by the Mec1 and Tel1 kinases appears to be essential for SSA but not for cell viability in the absence of Sgs1 or for cellular resistance to MMS. These results indicate that Slx4 has multiple functions in responding to DNA damage and that a subset of these are regulated by Mec1/Tel1-dependent phosphorylation.
Online Experiences and Virtual Goods Purchase Intention

Purpose – The purpose of this paper is to examine the effects of interactive and social features on users' online experiences and their purchase intention of virtual goods from a social network site.Design/methodology/approach – A banner with a hyperlink that connected to the author's web survey was posted on the homepage of Facebook. Of the 258 responses returned, 176 were fully completed. Measurement items were adapted from previous literature. Structural equation modeling (SEM) was used to evaluate the research model and hypotheses testing.Findings – The results of an empirical study supported the use of the stimuli‐organism‐response (S‐O‐R) model in a social networking site and showed how environmental features should be incorporated to enhance users' online experiences and purchase intentions. Specifically, social identity showed the strongest influence on involvement and flow. More specifically, affective involvement showed the greatest influence on purchase intention compared to flow and cognitive .
VSI: A Visual Saliency-Induced Index for Perceptual Image Quality Assessment

Perceptual image quality assessment (IQA) aims to use computational models to measure the image quality in consistent with subjective evaluations. Visual saliency (VS) has been widely studied by psychologists, neurobiologists, and computer scientists during the last decade to investigate, which areas of an image will attract the most attention of the human visual system. Intuitively, VS is closely related to IQA in that suprathreshold distortions can largely affect VS maps of images. With this consideration, we propose a simple but very effective full reference IQA method using VS. In our proposed IQA model, the role of VS is twofold. First, VS is used as a feature when computing the local quality map of the distorted image. Second, when pooling the quality score, VS is employed as a weighting function to reflect the importance of a local region. The proposed IQA index is called visual saliency-based index (VSI). Several prominent computational VS models have been investigated in the context of IQA and the best one is chosen for VSI. Extensive experiments performed on four largescale benchmark databases demonstrate that the proposed IQA index VSI works better in terms of the prediction accuracy than all state-of-the-art IQA indices we can find while maintaining a moderate computational complexity. The MATLAB source code of VSI and the evaluation results are publicly available online at http://sse.tongji. edu.cn/linzhang/IQA/VSI/VSI.htm.
Measuring the Field Corrosion Activity of Bridge Decks Built with Bare and Epoxy Coated Steel

Epoxy coated steel became the prevalent corrosion protection methods starting in the early 1980s. Since then, studies have shown that epoxy coating does not prevent corrosion, but instead will debond from the steel reinforcement in as little as four years, allowing instead a much more insidious form of corrosion to take place under the coating. Therefore, it is important to determine if nondestructive corrosion activity detection methods are applicable to epoxy coated reinforcing steel as well as institute guidelines for interpreting the results. Based on comparisons of measurements distributions, this study shows that there is an indication that these nondestructive test methods may be applicable to structures reinforced with epoxy coated steel.
Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men.

To determine the relation between habitual endurance exercise status and the age-associated decline in maximal aerobic capacity [i.e., maximal O(2) consumption (Vo(2 max))] in men, we performed a well-controlled cross-sectional laboratory study on 153 healthy men aged 20-75 yr: 64 sedentary and 89 endurance trained. Vo(2 max) (ml. kg(-1). min(-1)), measured by maximal treadmill exercise, was inversely related to age in the endurance-trained (r = -0.80) and sedentary (r = -0.74) men but was higher in the endurance-trained men at any age. The rate of decline in Vo(2 max) with age (ml. kg(-1). min(-1)) was greater (P < 0.001) in the endurance-trained than in the sedentary men. Whereas the relative rate of decline in Vo(2 max) (percent decrease per decade from baseline levels in young adulthood) was similar in the two groups, the absolute rate of decline in Vo(2 max) was -5.4 and -3.9 ml. kg(-1). min(-). decade(-1) in the endurance-trained and sedentary men, respectively. Vo(2 max) declined linearly across the age range in the sedentary men but was maintained in the endurance-trained men until approximately 50 yr of age. The accelerated decline in Vo(2 max) after 50 yr of age in the endurance-trained men was related to a decline in training volume (r = 0.46, P < 0.0001) and was associated with an increase in 10-km running time (r = -0.84, P < 0.0001). We conclude that the rate of decline in maximal aerobic capacity during middle and older age is greater in endurance-trained men than in their sedentary peers and is associated with a marked decline in O(2) pulse.
Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent

Treatment of cancers by means of viruses, that specifically replicate in (oncotropism) and kill (oncolysis) neoplastic cells, is increasingly gaining acceptance in the clinic. Among these agents, parvoviruses have been shown to possess not only direct oncolytic but also immunomodulating properties, serving as an adjuvant to prime the immune system to react against infected tumors. Here, we aimed to establish whether immunomodulating mechanisms participate in the recently reported therapeutic potential of parvoviruses against pancreatic carcinoma. Using adoptive transfer experiments we discovered that the transfer of splenocytes of donor rats harboring H-1PV-treated orthotopic PDAC tumors could significantly prolong the survival of naïve tumor-bearing recipients, compared to those receiving cells from mock-treated donors. Closer investigation of immunological parameters in infected donor rats revealed that virus-induced interferon gamma production and cellular immune response played an important role in this effect. These data have also preclinical relevance since abortive H-1PV infection of human peripheral blood mononuclear cells or cocultivation of these cells with H-1PV-preinfected pancreatic cancer cells, resulted in enhancement of innate and adaptive immune reactivity. Taken together our data reveal that oncolytic H-1PV modulates the immune system into an anticancer state, and further support the concept of using parvoviruses in the fight against pancreatic cancer.
Effect of tool rotation rate on microstructure and mechanical properties of friction stir welded copper

Defect free copper welds were achieved by friction stir welding (FSW) carried out at a constant welding speed of 100 mm min−1. The influence of tool rotation rate on microstructure, mechanical properties and fracture location was investigated. As the tool rotation rate increased, the grains of nugget zone grew significantly, the thermomechanically affected zone became indistinct and the grain size increased, but the effect of tool rotation rate on the grain size of heat affected zone was limited. Both ultimate tensile strength (UTS) and elongation increased first and then decreased with increasing rotation rate and the UTS achieved a highest value of 282 MPa at the rotation rate of 400 rev min−1 together with the welding speed of 100 mm min−1, which was on the level of the base metal. The fracture occurred at the cavity defect on the advancing side of the joint when the FSW was performed at a low tool rotation rate, while it occurred on the retreating side when the tool rotation rate was relatively high.
Ionically Crosslinked Chitosan Hydrogels for the Controlled Release of Antimicrobial Essential Oils and Metal Ions for Wound Management Applications

The emerging problems posed by antibiotic resistance complicate the treatment regime required for wound infections and are driving the need to develop more effective methods of wound management. There is growing interest in the use of alternative, broad spectrum, pre-antibiotic antimicrobial agents such as essential oils (e.g., tea tree oil, TTO) and metal ions (e.g., silver, Ag+). Both TTO and Ag+ have broad spectrum antimicrobial activity and act on multiple target sites, hence reducing the likelihood of developing resistance. Combining such agents with responsive, controlled release delivery systems such as hydrogels may enhance microbiocidal activity and promote wound healing. The advantages of using chitosan to formulate the hydrogels include its biocompatible, mucoadhesive and controlled release properties. In this study, hydrogels loaded with TTO and Ag+ exhibited antimicrobial activity against P. aeruginosa, S. aureus and C. albicans. Combining TTO and Ag+ into the hydrogel further improved antimicrobial activity by lowering the effective concentrations required, respectively. This has obvious advantages for reducing the potential toxic effects on the healthy tissues surrounding the wound. These studies highlight the feasibility of delivering lower effective concentrations of antimicrobial agents such as TTO and Ag+ in ionically crosslinked chitosan hydrogels to treat common wound-infecting pathogens.
Determining MPPT and anti-islanding techniques in a grid-tie PV inverter

Numerous methods are known for grid-tie photovoltaic inverters to track the maximum power point and to avoid islanding operation, but the inverter manufacturers generally do not publish which of these methods they have implemented in their products. This paper reviews the most common maximum power point tracking and anti-islanding methods and points out to power quality signatures they may leave in the voltage and current waveforms on both the AC and DC sides of the inverter. Armed with this information, input and output waveforms of a commercial 2 kW grid-tie PV system are examined in an effort to identify which MMPT and active anti-islanding techniques are embedded in the inverter. The inverter response to different levels of over voltages is also reported.
The CP of clefts

In the pages that follow I would like to review the main arguments for i. -ii. in light of the different kinds of focalization that the two CP structures lead to in clefts. The main emphasis of the discussion here will be on the particular shape of the articulated CP projection in clefts. Throughout I will limit my attention to structures where the clefted constituent is a DP (or a PP), either a subject or a direct /indirect object.
Finding coexpressed genes in counts-based data: an improved measure with validation experiments

MOTIVATION Expressed sequence tag (EST) data reflects variation in gene expression, but previous methods for finding coexpressed genes in EST data are subject to bias and vastly overstate the statistical significance of putatively coexpressed genes. RESULTS We introduce a new method (LNP) that reports reasonable p-values and also detects more biological relationships in human dbEST than do previous methods. In simulations with human dbEST library sizes, previous methods report p-values as low as 10(-30) on 1/1000 uncorrelated pairs, while LNP reports significance correctly. We validate the analysis on real human genes by comparing coexpressed pairs to gene ontology annotations and find that LNP is more sensitive than the three previous methods. We also find a small but statistically significant level of coexpression between interacting proteins relative to randomized controls. The LNP method is based on a log-normal prior on the distribution of expression levels.
Architecture blueprints—the “4+1” view model of software architecture

A portable cement mixer is provided with an improved supporting frame. The supporting frame includes a first, generally triangularly-shaped end frame comprising two upwardly-converging struts and intermediate cross struts. The second end frame comprises a single upright member. A transverse strut connects a central portion of the cross struts of the first end frame with an intermediate portion of the upright strut of the second end frame. The transverse strut is of rectangular cross section but varying in width and thickness from one end to the other. The new supporting frame is of simple construction and is easier to assemble. It is also sturdier and provides a three-point support for the mixer which can be more readily adapted to uneven ground.