Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of gender on transformational leadership and job satisfaction among Saudi nurses

AIM To compare nurses' job satisfaction and perceptions of transformational leadership style of their manager among four different nurse/manager gender dyads in Saudi Arabia. BACKGROUND Women and men differ on many behavioural characteristics and are influenced by the cultural environment. Understanding these differences may have an impact on leadership behaviours and job satisfaction. DESIGN A descriptive analysis of one-time survey data collected in 2011 from Saudi nurses employed in six general public hospitals located in three cities. METHOD Three hundred and eight (51.3%) of 600 Saudi nurses solicited to participate completed anonymous questionnaires that measured their job satisfaction and perceptions of transformational leadership style of their manager. FINDINGS Factorial ANOVA tested the main effects of gender of the nurse, gender of the manager and the interaction term on the nurse's job satisfaction, and perceived transformational leadership style of their manager. These analyses indicated a main effect of gender of the manager on both job satisfaction and perceived transformational leadership style of the manager (p < .05) with no significant effect of the gender of the nurse or the interaction term on these variables. Post hoc analysis indicated that nurses regardless of their gender reported higher job satisfaction and perceived transformational leadership style of their manager when their manager was male. CONCLUSION These findings contrast with what other researchers have reported that nurse job satisfaction and perceived leadership characteristics of their manager are independent of the gender of the manager. These perceptions of Saudi nurses may be a result of "sex-role spillover" in a male-dominated, gender-segregated society.
Serial cerebrospinal fluid neurofilament heavy chain levels in severe Guillain‐Barré syndrome

Proximal axonotmesis results in the release of neurofilament (Nf) proteins into the cerebrospinal fluid (CSF) in patients with Guillain‐Barré syndrome (GBS). High CSF levels of the phosphorylated form of Nf‐heavy chain (NfHSMI35) at GBS onset have been reported to be a poor prognostic marker, but routine measurement of CSF NfHSMI35 levels has not been done and the longitudinal profile of CSF NfHSMI35 levels in GBS is not known.
The Relationship between Parenting Styles and Adolescents’ Social Anxiety in Migrant Families: A Study in Guangdong, China

Previous studies indicated that parenting styles were important influencing factors for the development of children’s well-being. It is known that mass migration to the cities in China will affect family relations. However, few studies focused on the relationship between parenting styles and adolescents’ mental health in migrant families. Thus, this study aimed to investigate how parenting styles could affect adolescent’s social anxiety in migrant families. A total number of 1,345 adolescents in migrant families from four non-government-funded junior middle schools in Guangdong province formed the research sample. Parenting styles were measured using short-form of the Egna Minnen Beträffande Uppfostran, and social anxiety was evaluated using Social Anxiety Subscale of Self-Consciousness Scale. The results showed that emotional warmth, overprotection and rejection were significantly more often perceived from mothers than from fathers. Significant group differences between high social anxiety group and low social anxiety group were found in both father’s rearing styles and mother’s rearing styles. Furthermore, in migrant families, paternal emotional warmth could decrease adolescents’ social anxiety, whereas maternal overprotection could increase it.
Further results on the stability of distance-based multi-robot formations

An important class of multi-robot formations is specified by desired distances between adjacent robots. In previous work, we showed that distance-based formations can be globally stabilized by negative gradient, potential field based, control laws, if and only if the formation graph is a tree. In this paper, we further examine the relation between the cycle space of the formation graph and the resulting equilibria of cyclic formations. In addition, the results are extended to the case of distance based formation control for nonholonomic agents. The results are supported through computer simulations.
The Emergence and Potential Impact of Medicine 2.0 in the Healthcare Industry

Abstract Medicine 2.0 has emerged within healthcare information technology to enable more defined relationships among providers and patients. Physicians, hospitals, and patients are using Medicine 2.0 through social networking to maintain their foothold in the evolution of medical technologies. The authors’ purpose was to determine potential improvements that Medicine 2.0 has on communication and collaboration of healthcare information. Research has shown that Medicine 2.0 has integrated into the healthcare industry and is enabling an increase in communication in healthcare matters. The provider-patient relationship is improving through the use of Medicine 2.0 and has positively impacted society so far.
Measuring semantic content in distributional vectors

Some words are more contentful than others: for instance, make is intuitively more general than produce and fifteen is more ‘precise’ than a group. In this paper, we propose to measure the ‘semantic content’ of lexical items, as modelled by distributional representations. We investigate the hypothesis that semantic content can be computed using the KullbackLeibler (KL) divergence, an informationtheoretic measure of the relative entropy of two distributions. In a task focusing on retrieving the correct ordering of hyponym-hypernym pairs, the KL divergence achieves close to 80% precision but does not outperform a simpler (linguistically unmotivated) frequency measure. We suggest that this result illustrates the rather ‘intensional’ aspect of distributions.
Effect of recombinant human granulocyte macrophage‐colony stimulating factor in long‐term marrow cultures from patients with aplastic anemia

The hematopoietic system in patients with aplastic anemia (AA) shows both quantitative and qualitative deficiencies, i.e., reduced numbers of hematopoietic progenitor cells (HPC) and impaired HPC proliferation in long‐term marrow cultures (LTMC). Since recombinant human granulocyte macrophage‐colony stimulating factor (rhGM‐CSF) has been shown to be a potent stimulator of normal hematopoiesis, both in vivo and in vitro, in the present study we wanted to assess the possibility of stimulating hematopoiesis in LTMC from 17 patients with AA, by weekly addition of rhGM‐CSF (10 ng/ml). In LTMC from 11 patients (group of responders), rhGM‐CSF induced a significant increase (4.8‐fold, compared with untreated cultures) in the levels of myeloid progenitor cells; in contrast, in six patients (group of nonresponders), myeloid progenitors were refractory to this cytokine. In the group of responders, rhGM‐CSF also induced a pronounced increment in the levels of nonadherent and adherent cells (5.99‐ and 5.18‐fold, respectively, compared with untreated cultures). Among the different myelopoietic lineages, rhGM‐CSF preferentially stimulated the macrophagic lineage; this was evident both at the progenitor and mature cell levels. Interestingly, the effect of rhGM‐CSF in LTMC from AA patients was only transient. Indeed, the effects mentioned above were observed only during the first three weeks of culture; afterwards, myeloid progenitor and nonadherent cell levels in treated cultures declined, practically reaching the levels observed in untreated cultures. At the moment, we do not know whether this transient stimulatory effect is due to the production of inhibitory cytokines, by macrophages generated in response to rhGM‐CSF, or to the exhaustion of the HPC pool in AA cultures. In all 17 patients, rhGM‐CSF had no effect on the kinetics of erythroid or multipotent progenitor cells. These results are in keeping with clinical studies in which it has been observed that most AA patients treated with rhGM‐CSF show increments in circulating monocytes and granulocytes, as well as in bone marrow cellularity. However, little or no effect is observed on erythropoiesis. The actual mechanisms involved in the in vitro effects of rhGM‐CSF on myeloid progenitor cells from AA bone marrow are still not completely understood. Future studies on this issue should be encouraged, since they may help to understand the in vivo (clinical) effects of this cytokine. Am. J. Hematol. 61:107–114, 1999. © 1999 Wiley‐Liss, Inc.
Modeling and Inferring Cleavage Patterns in Proliferating Epithelia

The regulation of cleavage plane orientation is one of the key mechanisms driving epithelial morphogenesis. Still, many aspects of the relationship between local cleavage patterns and tissue-level properties remain poorly understood. Here we develop a topological model that simulates the dynamics of a 2D proliferating epithelium from generation to generation, enabling the exploration of a wide variety of biologically plausible cleavage patterns. We investigate a spectrum of models that incorporate the spatial impact of neighboring cells and the temporal influence of parent cells on the choice of cleavage plane. Our findings show that cleavage patterns generate “signature” equilibrium distributions of polygonal cell shapes. These signatures enable the inference of local cleavage parameters such as neighbor impact, maternal influence, and division symmetry from global observations of the distribution of cell shape. Applying these insights to the proliferating epithelia of five diverse organisms, we find that strong division symmetry and moderate neighbor/maternal influence are required to reproduce the predominance of hexagonal cells and low variability in cell shape seen empirically. Furthermore, we present two distinct cleavage pattern models, one stochastic and one deterministic, that can reproduce the empirical distribution of cell shapes. Although the proliferating epithelia of the five diverse organisms show a highly conserved cell shape distribution, there are multiple plausible cleavage patterns that can generate this distribution, and experimental evidence suggests that indeed plants and fruitflies use distinct division mechanisms.
Molecular and Functional Characterization of a Trypanosoma cruzi Nuclear Adenylate Kinase Isoform

Trypanosoma cruzi, the etiological agent of Chagas' disease, is an early divergent eukaryote in which control of gene expression relies mainly in post-transcriptional mechanisms. Transcription levels are globally up and down regulated during the transition between proliferating and non-proliferating life-cycle stages. In this work we characterized a nuclear adenylate kinase isoform (TcADKn) that is involved in ribosome biogenesis. Nuclear adenylate kinases have been recently described in a few organisms, being all related to RNA metabolism. Depending on active transcription and translation, TcADKn localizes in the nucleolus or the cytoplasm. A non-canonical nuclear localization signal was mapped towards the N-terminal of the protein, being the phosphate-binding loop essential for its localization. In addition, TcADKn nuclear exportation depends on the nuclear exportation adapter CRM1. TcADKn nuclear shuttling is governed by nutrient availability, oxidative stress and by the equivalent in T. cruzi of the mammalian TOR (Target of Rapamycin) pathway. One of the biological functions of TcADKn is ribosomal 18S RNA processing by direct interaction with ribosomal protein TcRps14. Finally, TcADKn expression is regulated by its 3′ UTR mRNA. Depending on extracellular conditions, cells modulate protein translation rates regulating ribosome biogenesis and nuclear adenylate kinases are probably key components in these processes.
Effects of ISO 9000 certification on companies ’ profitability : an empirical study Prof

In this article the authors analyzed the effects on certified companies of the implementation and certification according to ISO 9000 standards. Firstly, the authors synthesized the benefits achieved by the application of this standard according to both the theoretical and empirical research of recent years. The authors emphasized the need to focus on issues related to the effects of the standards on the companies’ performance in order to objectify the benefits that the companies achieve. To analyze some of the questions formulated by this line of reasoning, the authors conducted an empirical investigation. In summary, the authors analyzed the consequences of compliance with ISO 9000 standards on the companies’ economic performance by means of an empirical survey conducted with a business information database composed of one group of 400 certified companies, and another group of 400 noncertified companies.
Hepatitis B virus replication is cell cycle independent during liver regeneration in transgenic mice

The content of hepatitis B virus (HBV) replicative forms and HBV core protein in the liver of HBV transgenic mice is transiently reduced during massive liver regeneration following partial hepatectomy while the steady-state content of viral RNA is unchanged. This antiviral effect is triggered by interferon and tumor necrosis factor that are induced in the liver following hepatectomy and either prevent the formation or accelerate the degradation of viral nucleocapsids in the cytoplasm of the hepatocyte. Despite massive hepatocellular turnover, this effect is independent of liver cell division, indicating that HBV replicates efficiently in resting and dividing hepatocytes.
Microwave, Spark Plasma and Conventional Sintering to Obtain Controlled Thermal Expansion β‐Eucryptite Materials

Lithium aluminosilicate was fabricated by conventional and nonconventional sintering: microwave and spark plasma sintering, from 1200 to 1300°C. A considerable difference in densification, microstructure, coefficient of thermal expansion behavior and hardness and Young's modulus was observed. Microwave technology made possible to obtain fully dense glass-free lithium aluminosilicate bulk material (>99%) with near-zero and controlled coefficient of thermal expansion and relatively high mechanical properties (7.1 GPa of hardness and 110 GPa of Young's modulus) compared with the other two processes. It is believed that the heating mode and effective particle packing by microwave sintering are responsible to improve these properties.
Efektivitas Ekstrak Daun Dewa (Gynura Pseudochina (Lour.) Dc) Terhadap Pertumbuhan Candida Albicans Pada Plat Dasar Gigi Tiruan Resin Akrilik

Daun dewa is tradional medicine plants, containts flavonoid, saponin alkaloid, tannin and atsiri oil. The aim of this research is to know the effect of daun dewa extract to the growth of candida albicans on acrylic resin denture base. The research used 31 heat cured acrylic resin discuses with 10 mm in diameterÂ and 2 mm in thickness. The subjects were incubated in 10 ml candida albicans suspension for 24 hours at 37 â° C. the subjects were divided into 3 groups . each group consisted of 10 acrilic resin discuses soaked in daun dewa extract with different concentration , 25%, 5%, 10%. The control was soaked in sterile aquades. The duration of soaking was 8 hours at room temperature. The solution 0. ,01 ml from serial dilutions 10 â» Â³ were planted in sabouraund dextrose Agar Media. They were incubated. Four 48 hours at 37 â° and the colonies of candida albicans were counted. The collected data were analyzed by using one way Analysis varian and t-test. The result showed that there was a significant difference of daun dewa extract among 2,5%, 5% and 10% concentrations to the growth of candida albicans (p<0.05). the conclution of this research was that the daun dewa extrac has an effect to reduce the growth of candida albicans on acrylic resin denture base. 10% concentrations of daun dewa extract is the most effective in reducing to the growth of candida albicans. Keyword : daun dewa, candida albicans, acrylic resin denture base
LOSSES IN M=GI=m=n QUEUES

The M/GI/m/n queueing system with m homogeneous servers and the finite number n of waiting spaces is studied. Letbe the customers arrival rate, and let µ be the reciprocal of the expected service time of a customer. Under the assumption � = mµ it is proved that the expected number of losses during a busy period is the same value for all n � 1, while in the particular case of the Markovian system M/M/m/n the expected number of losses during a busy period is m m m! for all n � 0. Under the additional assumption that the probability distribution function of a service time belongs to the class NBU or NWU, the paper establishes simple inequalities for those expected numbers of losses in M/GI/m/n queueing systems. Analysis of loss queueing systems is very important from both the theoretical and practical points of view. While the multiserver loss queueing system M=GI=m=0 and its network extensions have been intensively studied (see the review paper of Kelly (20), the book of Ross (27) and references in these sources), the information about M=GI=m=n queueing systems (n � 1) is very scanty, because explicit results for characteristics of these queueing systems are unknown. (In the present paper, for multiserver queueing systems the notation M=GI=m=n is used, where m denotes the number of servers and n denotes the number of waiting places. Another notation which is also acceptable in the literature is M=GI=m=m + n.) From the practical point of view, M=GI=m=n queueing systems serve as a model for telephone systems, where n is the maximally possible number of calls that can wait in the line before their service start. The loss probability is one of the most significant performance characteristics. In the present paper, we study the expected number of losses during a busy period (the characteristic closely related to the stationary loss probability) under the assumption that the arrival rate (�) is equal to the maximum service capacity (m�), which seems to be the most interesting from the theoretical point of view. There are two main reasons for studying this case. The first reason is that the case � = mis a critical case for queueing systems with m identical servers, i.e. the case associated with critically loaded systems. The theoretical and practical interest in studying heavily loaded loss systems is very high, and there are many results in the literature related to the analysis of the loss probability in heavily loaded systems. The asymptotic results for losses in heavily loaded single server systems (n ! 1 ) such as M=GI=1=n and GI=M=1=n
Differential Expression of Serum Clusterin Isoforms in Colorectal Cancer*

Clusterin is an enigmatic protein altered in tumors of colorectal cancer patients. Because there is no information available about serum clusterin regarding this pathology, we applied proteomic techniques to analyze its isoforms in donors and patients. First we separated serum proteins through concanavalin A, obtaining a fraction with non- and O-glycosylated proteins (FI) and a second fraction enriched in N-glycoproteins (FII) wherein clusterin was supposed to elute on the basis of its glycosylation. Surprisingly analysis of the FI fraction revealed the existence of an unexpected and aberrantly N-glycosylated clusterin that was overexpressed in patients and comprised at least five isoforms with different isoelectric points. On the other hand, two-dimensional electrophoretic analysis of the clusterin eluted in FII detected one isoform that was increased and 15 isoforms that were decreased or absent in serum of patients. Finally immunoquantification by slot blot showed that in total serum and in FI the clusterin levels were significantly increased in patients, whereas in FII there was no significant variation. Therefore, serum clusterin and some of its isoforms could have a potential value as colorectal tumor markers and are interesting subjects for biomarker studies.
SEU-Mitigation Placement and Routing Algorithms and Their Impact in SRAM-Based FPGAs

In this paper, the authors propose a new SEU-mitigative placement and routing of circuits in the FPGAs which is based on the popular VPR tool. The VPR tool is modified so that during placement and routing, decisions are taken with awareness of SEU-mitigation. Moreover, no redundancies during the placement and routing are used but the algorithms are based on the SEU avoidance. Using the modified tool, i.e., S-VPR, the role of placement and routing algorithms on the fault-tolerance of circuits implemented on FPGAs is achieved. The secondary propose of this paper is to find which of placement or routing is more suited for decreasing SEU sensibility of circuits and to find whether these SEU sensibility reductions are cumulative or not when they applied in sequence. We have investigated the effect of S-VPR on several MCNC benchmarks and the results of the placement and routing have been compared to the traditional one. The evaluations of results show that placement and routing can decrease the SEU rate of circuits implemented on FPGAs about 18% and 12%, respectively. However, it increases critical path delay and power consumptions of the circuits up to 5% and 8%, respectively. This means that without any redundancies, just by means of fault-avoidance method, mitigation of SEU effects would decrease up to 22% significantly and this method is notable compared to previous TMR and DWC mechanisms
The relationship between an inflammation-based prognostic score (Glasgow Prognostic Score) and changes in serum biochemical variables in patients with advanced lung and gastrointestinal cancer

Background: The Glasgow Prognostic Score (GPS), an inflammation-based prognostic score formed from standard thresholds of C reactive protein (CRP) and albumin, has prognostic value in patients with advanced cancer. Little is known about the general biochemical disturbance associated with the systemic inflammatory response in cancer. Aim: To examine the relationship between the GPS and blood biochemistry in patients with advanced lung and gastrointestinal cancer. Methods: The GPS (albumin <35 g/l = 1 and CRP >10 mg/l = 1 combined to form a prognostic score of 0 (normal) and 1 or 2 (abnormal)) and a variety of biochemical variables were examined in patients (n = 50) with advanced lung or gastrointestinal cancer and in a healthy control group (n = 13). Results: The GPS was normal in all the controls, but abnormal in 78% of the cancer group. Serum levels of sodium, chloride, creatine kinase, zinc and vitamin D were lower in the cancer group (all p<0.01), whereas levels of calcium, copper (both p<0.05), alkaline phosphatase, γ-glutamyl transferase (both p<0.001) and lactate dehydrogenase (p<0.10) were raised. In the patient group, with increasing GPS, there was a median reduction in Karnofsky Performance Status (25%), haemoglobin (22%), sodium (3%), zinc (15%) and survival (93%, all p<0.05) and a median increase in white cell count (129%), alkaline phosphatase (217%), γ-glutamyl transferase (371%) and lactate dehydrogenase (130%, all p<0.05). CRP levels were strongly and similarly correlated with alkaline phosphatase and γ-glutamyl transferase, accounting for more than 25% of the variation in their activities. Conclusion: Several correlations were seen between biochemical variables and increasing GPS. In particular, chronic activation of the systemic inflammatory response in cancer was associated with increase in γ-glutamyl transferase and alkaline phosphatase activity in patients with advanced lung and gastrointestinal cancer.