Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic Image Haze Removal Based on Luminance Component

In this paper, we propose a simple but effective method for visibility restoration from a single image. The main advantage of the proposed algorithm is no user interaction is needed, this allows our algorithm to be applied for practical applications, such as surveillance, intelligent vehicle, etc. Another advantage compared with others is its speed, since the cost of obtaining transmission map is greatly cut down by using Retinex algorithm on luminance component. A comparative study and quantitative evaluation is proposed with the main present-day methods which demonstrate that similar or better quality results are obtained.
Dexrazoxane for anthracycline extravasation

Accidental extravasation of anthracycline-containing anticancer chemotherapy is a feared complication that may lead to progressive tissue damage. The condition may require extensive surgical intervention and often has severe long-term effects. Until a short while ago, there has been no effective treatment against the devastating effect of extravasated anthracycline. However, dexrazoxane has proven highly effective in preventing necrosis in both preclinical and clinical studies and is now approved in Europe (Savene™), and has orphan drug status in the USA (Totect™) for this indication. Hence, it is the first and only proven effective antidote against anthracycline extravasation injuries.
Evaluating the Feasibility of Traffic-Based Intrusion Detection in an 802.15.4 Sensor Cluster

We investigate the feasibility of a simple, traffic volume-based intrusion detection for an IEEE 802.15. 4 compliant sensor cluster operating in beacon-enabled, slotted CSMA-CA mode. We have used simple exponential averaging to filter out some of the inherent variability in individual device arrival rate, and introduced a small hysteresis in the decision process in order to avoid false alarms due to dithering. Initial results demonstrate that the intrusion detection implemented in this manner may indeed operate quickly and efficiently.
Transferring x-ray based automated threat detection between scanners with different energies and resolution

A significant obstacle to developing high performance Deep Learning algorithms for Automated Threat Detection (ATD) in security X-ray imagery, is the difficulty of obtaining large training datasets. In our previous work, we circumvented this problem for ATD in cargo containers, using Threat Image Projection and data augmentation. In this work, we investigate whether data scarcity for other modalities, such as parcels and baggage, can be ameliorated by transforming data from one domain so that it approximates the appearance of another. We present an ontology of ATD datasets to assess where transfer learning may be applied. We define frameworks for transfer at the training and testing stages, and compare the results for both methods against ATD where a common data source is used for training and testing. Our results show very poor transfer, which we attribute to the difficulty of accurately matching the blur and contrast characteristics of different scanners.
Enduring Gender Bias in Reporting on Political Elite Positions

In Belgium, like in numerous other democracies, the representation of women in parliament has risen sharply in recent decades, partly because of gender quota legislation. This rapid evolution implies that traditional notions on the presence of gender bias in media reporting need to be re-assessed. Relying on data from more than six thousand full newscasts, we examine the allotted speaking time to members of parliament (MPs) from 2003 until 2011 in the two main television news broadcasts in the Dutch-speaking region of Belgium. Multilevel regression analyses were conducted to determine which factors influence the probability and volume of television news coverage of MPs. The results indicate that—even controlling for alternative explanations—news media persist in a biased treatment of female MPs: Female MPs are significantly less likely to be allotted speaking time, and they receive less speaking time than their male colleagues. Moreover, results show that this gap in media coverage is present especially for elite and thus newsworthy positions. Apparently, gender bias in the media persists, even when the political system evolves rapidly toward equal representation.
The Milky Way Tomography with SDSS. I. Stellar Number Density Distribution

Using the photometric parallax method we estimate the distances to ~48 million stars detected by the Sloan Digital Sky Survey (SDSS) and map their three-dimensional number density distribution in the Galaxy. The currently available data sample the distance range from 100 pc to 20 kpc and cover 6500 deg2 of sky, mostly at high Galactic latitudes (|b| > 25). These stellar number density maps allow an investigation of the Galactic structure with no a priori assumptions about the functional form of its components. The data show strong evidence for a Galaxy consisting of an oblate halo, a disk component, and a number of localized overdensities. The number density distribution of stars as traced by M dwarfs in the solar neighborhood (D < 2 kpc) is well fit by two exponential disks (the thin and thick disk) with scale heights and lengths, bias corrected for an assumed 35% binary fraction, of H1 = 300 pc and L1 = 2600 pc, and H2 = 900 pc and L2 = 3600 pc, and local thick-to-thin disk density normalization ρthick(R☉)/ρthin(R☉) = 12% . We use the stars near main-sequence turnoff to measure the shape of the Galactic halo. We find a strong preference for oblate halo models, with best-fit axis ratio c/a = 0.64, ρH ∝ r−2.8 power-law profile, and the local halo-to-thin disk normalization of 0.5%. Based on a series of Monte Carlo simulations, we estimate the errors of derived model parameters not to be larger than ~20% for the disk scales and ~10% for the density normalization, with largest contributions to error coming from the uncertainty in calibration of the photometric parallax relation and poorly constrained binary fraction. While generally consistent with the above model, the measured density distribution shows a number of statistically significant localized deviations. In addition to known features, such as the Monoceros stream, we detect two overdensities in the thick disk region at cylindrical galactocentric radii and heights (R,Z) ∼ (6.5,1.5) kpc and (R,Z) ∼ (9.5,0.8) kpc and a remarkable density enhancement in the halo covering over 1000 deg2 of sky toward the constellation of Virgo, at distances of ~6-20 kpc. Compared to counts in a region symmetric with respect to the l = 0° line and with the same Galactic latitude, the Virgo overdensity is responsible for a factor of 2 number density excess and may be a nearby tidal stream or a low-surface brightness dwarf galaxy merging with the Milky Way. The u − g color distribution of stars associated with it implies metallicity lower than that of thick disk stars and consistent with the halo metallicity distribution. After removal of the resolved overdensities, the remaining data are consistent with a smooth density distribution; we detect no evidence of further unresolved clumpy substructure at scales ranging from ~50 pc in the disk to ~1-2 kpc in the halo.
Social interaction modulates autonomic, inflammatory, and depressive-like responses to cardiac arrest and cardiopulmonary resuscitation

Psychological factors, including depression and social isolation, are important determinants of cardiovascular health. The current study uses a well-validated mouse model of cardiac arrest/cardiopulmonary resuscitation (CA/CPR) to examine the effect of social environment on several pathophysiological and behavioral responses to cerebral ischemia. Male experimental mice were either housed in pairs with an ovariectomized female or socially isolated for the duration of the experiment. Cardiac arrest increased the mRNA expression of the proinflammatory cytokines TNF-α, IL-1β, and IL-6, as well as the microglia marker MAC-1; expression of each of these factors, except IL-6, was further increased among socially isolated mice. Furthermore, socially isolated animals exposed to the CA/CPR procedure displayed significantly higher levels of neuronal cell death and microglia staining within the hippocampus at 7 d following surgery. Social isolation also exacerbated CA/CPR-induced depressive-like behavior and cardiac autonomic dysregulation. In the absence of ischemic damage, social environment had no significant effect on the expression of neuronal cell death, autonomic cardiac control, or behavior. Together, these data suggest that social factors influence the pathophysiological trajectory following cardiac arrest.
Comparative study of the distribution of the α‐subunits of voltage‐gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

We compared the distribution of the α‐subunit mRNAs of voltage‐gated sodium channels Nav1.1–1.3 and Nav1.6–1.9 and a related channel, Nax, in histochemically identified neuronal subpopulations of the rat dorsal root ganglia (DRG). In the naïve DRG, the expression of Nav1.1 and Nav1.6 was restricted to A‐fiber neurons, and they were preferentially expressed by TrkC neurons, suggesting that proprioceptive neurons possess these channels. Nav1.7, ‐1.8, and ‐1.9 mRNAs were more abundant in C‐fiber neurons compared with A‐fiber ones. Nax was evenly expressed in both populations. Although Nav1.8 and ‐1.9 were preferentially expressed by TrkA neurons, other α‐subunits were expressed independently of TrkA expression. Actually, all IB4+ neurons expressed both Nav1.8 and ‐1.9, and relatively limited subpopulations of IB4+ neurons (3% and 12%, respectively) expressed Nav1.1 and/or Nav1.6. These findings provide useful information in interpreting the electrophysiological characteristics of some neuronal subpopulations of naïve DRG. After L5 spinal nerve ligation, Nav1.3 mRNA was up‐regulated mainly in A‐fiber neurons in the ipsilateral L5 DRG. Although previous studies demonstrated that nerve growth factor (NGF) and glial cell‐derived neurotrophic factor (GDNF) reversed this up‐regulation, the Nav1.3 induction was independent of either TrkA or GFRα1 expression, suggesting that the induction of Nav1.3 may be one of the common responses of axotomized DRG neurons without a direct relationship to NGF/GDNF supply. J. Comp. Neurol. 510:188–206, 2008. © 2008 Wiley‐Liss, Inc.
Role of the renal sympathetic nerves in renal sodium/potassium handling and renal damage in spontaneously hypertensive rats

Renal sympathetic nerve activity has an important role in renal disease-associated hypertension and in the modulation of fluid homeostasis. In the present study, changes in renal function and renal sodium/potassium handling were investigated in groups of 12-week-old male, spontaneously hypertensive rats with renal denervation (RDNX group) or sham denervation (sham group). The RDNX group excreted significantly more sodium than the sham group during the 2-week observation period (P<0.05). Following bilateral renal denervation, the fractional lithium excretion was elevated in the RDNX group compared with the sham group, but no significant effect was observed of renal denervation on the fractional distal reabsorption rate of sodium or the fractional excretion of potassium. Furthermore, the glomerular injury score and the wall-to-lumen ratio of the interlobular artery were significantly lower in the RDNX group than in the sham group (P<0.05). In conclusion, the present study indicates an involvement of the renal sympathetic nerves in the regulation of renal tubular sodium reabsorption in spontaneously hypertensive rats and in the renal damage associated with hypertension.
Portable mapping of data parallel programs to OpenCL for heterogeneous systems

General purpose GPU based systems are highly attractive as they give potentially massive performance at little cost. Realizing such potential is challenging due to the complexity of programming. This paper presents a compiler based approach to automatically generate optimized OpenCL code from data-parallel OpenMP programs for GPUs. Such an approach brings together the benefits of a clear high level-language (OpenMP) and an emerging standard (OpenCL) for heterogeneous multi-cores. A key feature of our scheme is that it leverages existing transformations, especially data transformations, to improve performance on GPU architectures and uses predictive modeling to automatically determine if it is worthwhile running the OpenCL code on the GPU or OpenMP code on the multi-core host. We applied our approach to the entire NAS parallel benchmark suite and evaluated it on two distinct GPU based systems: Core i7/NVIDIA GeForce GTX 580 and Core 17/AMD Radeon 7970. We achieved average (up to) speedups of 4.51× and 4.20× (143× and 67×) respectively over a sequential baseline. This is, on average, a factor 1.63 and 1.56 times faster than a hand-coded, GPU-specific OpenCL implementation developed by independent expert programmers.
Inhibition of the fungal fatty acid synthase type I multienzyme complex

Fatty acids are among the major building blocks of living cells, making lipid biosynthesis a potent target for compounds with antibiotic or antineoplastic properties. We present the crystal structure of the 2.6-MDa Saccharomyces cerevisiae fatty acid synthase (FAS) multienzyme in complex with the antibiotic cerulenin, representing, to our knowledge, the first structure of an inhibited fatty acid megasynthase. Cerulenin attacks the FAS ketoacyl synthase (KS) domain, forming a covalent bond to the active site cysteine C1305. The inhibitor binding causes two significant conformational changes of the enzyme. First, phenylalanine F1646, shielding the active site, flips and allows access to the nucleophilic cysteine. Second, methionine M1251, placed in the center of the acyl-binding tunnel, rotates and unlocks the inner part of the fatty acid binding cavity. The importance of the rotational movement of the gatekeeping M1251 side chain is reflected by the cerulenin resistance and the changed product spectrum reported for S. cerevisiae strains mutated in the adjacent glycine G1250. Platensimycin and thiolactomycin are two other potent inhibitors of KSs. However, in contrast to cerulenin, they show selectivity toward the prokaryotic FAS system. Because the flipped F1646 characterizes the catalytic state accessible for platensimycin and thiolactomycin binding, we superimposed structures of inhibited bacterial enzymes onto the S. cerevisiae FAS model. Although almost all side chains involved in inhibitor binding are conserved in the FAS multienzyme, a different conformation of the loop K1413–K1423 of the KS domain might explain the observed low antifungal properties of platensimycin and thiolactomycin.
A functional neuroimaging investigation of deep brain stimulation in patients with obsessive-compulsive disorder.

OBJECT Deep brain stimulation (DBS) of the ventral [anterior internal] capsule/ventral striatum (VC/VS) is under investigation as an alternative to anterior capsulotomy for severe obsessive-compulsive disorder (OCD). In neuroimaging studies of patients with OCD, dysfunction in the orbitofrontal and anterior cingulate cortex, striatum, and thalamus has been identified; and modulation of activity in this circuit has been observed following successful nonsurgical treatment. The purpose of the current study was to test hypotheses regarding changes in regional cerebral blood flow (rCBF) during acute DBS at the VC/VS target in patients with OCD who were participating in a clinical DBS trial. METHODS Six patients enrolled in a DBS trial for OCD underwent positron emission tomography to measure rCBF; the rCBF measured during acute DBS at high frequency was then compared with those measured during DBS at low frequency and off (control) conditions. On the basis of neuroanatomical knowledge about the VC/VS and neuroimaging data on OCD, the authors predicted that acute DBS at this target would result in modulation of activity within the implicated frontal-basal ganglia-thalamic circuit. Data were analyzed using statistical parametric mapping. In a comparison of acute high-frequency DBS with control conditions, the authors found significant activation of the orbitofrontal cortex, anterior cingulate cortex, striatum, globus pallidus, and thalamus. CONCLUSIONS Acute DBS at the VC/VS target is associated with activation of the circuitry implicated in OCD. Further studies will be necessary to replicate these findings and to determine the neural effects associated with chronic VC/VS DBS. Moreover, additional data are needed to investigate whether pretreatment imaging profiles can be used to predict a patient's subsequent clinical response to chronic DBS.
Students’ experiences of active engagement through cooperative learning activities in lectures

This article reports on students’ experiences of lectures which included many opportunities for active engagement through cooperative learning activities. At the end of a 13-week semester-long unit, 113 students completed a questionnaire which contained five open-ended questions focusing on the extent to which the students thought that the lecture activities helped them to learn and understand the course content and to maintain their interest and attention during the sessions. Results indicate that students valued the mix of traditional lecturing and cooperative learning tasks, particularly the variety of activities, the opportunities for small-group and whole-class discussions, the clear focus on one or two central ideas, and the authenticity of the tasks.
Values, autonomy and well-being: implications for learning and teaching in physical education

The paper focuses on the possibilities for physical education as an effective policy conduit and constructive contributor to the type of life-affirming values which are widely endorsed. After a critical review of recent well-being theorising, ideas on how values central to physical education and well-being could be coherently conceptualised are advanced. Underpinning discussion is a focus on merging subjective and objective character traits in ways which recognise the importance of pupil autonomy, time for reflection and respect for others. This is followed by a review of how such values could inform learning arrangements, where there is an added emphasis on dialogue and shared discussion, and strategies which use language to help make pupils’ reasoning more explicit. The paper concludes by highlighting how clarity on subject values coupled with pedagogical changes could help physical education articulate its benefits better during a time of heightened policy expectancy.
The hidden value of sporadic customers in e-retailing: An empirical investigation

Purpose – To analyze empirically the transaction profitability derived from sporadic and frequent customers in the e‐retailing sector of minor home appliances in Brazil.Design/methodology/approach – A company's database was analyzed quantitatively to assess the transaction profitability derived from sporadic and frequent customers purchasing via the firm's digital channel, namely its web site. Besides, qualitative evidence was also collected from interviews with the main professionals involved in marketing and e‐commerce in the firm and through analysis of the company's web site and e‐mail communications with customers.Findings – The commercial transaction profitability associated with sporadic customers can be higher than that derived from frequent purchasers.Research limitations/implications – The study concentrated on a single company within a specific industry (minor home appliance e‐retailing) based in a specific country, namely Brazil.Practical implications – The benefits of web consumer retention w.
Subliminal Interdependence Priming Modulates Congruent and Incongruent Facial Reactions to Emotional Displays

To investigate how facial reactions to facial emotional displays are modulated by cues about social interdependence processed outside of awareness, 84 women were subliminally primed with cooperation or competition or neutrally primed. Thereafter, they viewed computer-generated faces with happy, neutral, sad, and angry expressions while facial EMG was recorded over three muscles. As expected, we observed congruent facial reactions in the neutral and cooperation conditions to happy and sad but not to angry faces. In the competition condition, we found almost no congruent reactions. Furthermore, we observed incongruent reactions to angry expressions: participants primed with competition and participants primed with cooperation showed positive reactions, but on different muscles. We argue that these incongruent reactions are based on reward contingencies and on habitual communicative goals to support a partner, respectively.
Evaluation of recellularization on decellularized aorta scaffolds engineered by ultrasonication treatment

Aortic scaffolds prepared using sonication decellularization treatment has provided a successful medium for repopulation with vascular smooth muscle cells (VSMCs). The objective of this study is to explore the potential of tissue decellularization using ultrasonication treatment and its recellularization before implantation of the cell-seeded scaffolds into host. Aorta tissue samples are decellularized in 2% SDS with sonication for 10 hours and compared with the native tissues. The 4′,6-diamidino-2-phenylindole (DAPI) staining was used to evaluate the decellularization and Hematoxylin-Eosin (H-E) staining was used to compare the VSMCs infiltrations onto the decellularized tissues at day-0 and day-6 after cell-seeding. The results histologically showed complete DNA removal from scaffolds after decellularization and subsequent recellularization resulted in successful VSMCs infiltration. Accordingly, the decellularized tissues treated with 2% SDS in sonication demonstrated successful VSMCs repopulation afterward and is speculated to have less toxicity and able to be effectively implanted into host.
Identifying Student Traits and Motives to Service-Learn: Public Service Orientation among New College Freshmen.

Among college students, public service motives influence choice of major or job. Although the link between public service motives and prosocial behavior has been established among working adults, researchers have not adequately examined how these motives affect the reported behavior of precareer students. In this article, the authors explored how public service motives and certain demographic characteristics were related to the service orientation of college freshmen. More specifically, they exam ined whether public service motivation was related to a student’s proclivity to enroll in service-learning courses and volunteer frequently. Results indicated that public service motives were positively associated with both curricular and extracurricular public service activities among first-year college students. Race and gender were found to be key traits affecting engagement. The implications of these findings for public service research and education are discussed.