Miracle-dz/UniFAR-FTUs huggingface dataset:
Mutual Use of Trail-Following Chemical Cues by a Termite Host and Its Inquiline

Termite nests are often secondarily inhabited by other termite species ( = inquilines) that cohabit with the host. To understand this association, we studied the trail-following behaviour in two Neotropical species, Constrictotermes cyphergaster (Termitidae: Nasutitermitinae) and its obligatory inquiline, Inquilinitermes microcerus (Termitidae: Termitinae). Using behavioural experiments and chemical analyses, we determined that the trail-following pheromone of C. cyphergaster is made of neocembrene and (3Z,6Z,8E)-dodeca-3,6,8-trien-1-ol. Although no specific compound was identified in I. microcerus, workers were able to follow the above compounds in behavioural bioassays. Interestingly, in choice tests, C. cyphergaster prefers conspecific over heterospecific trails while I. microcerus shows the converse behaviour. In no-choice tests with whole body extracts, C. cyphergaster showed no preference for, while I. microcerus clearly avoided heterospecific trails. This seems to agree with the hypothesis that trail-following pheromones may shape the cohabitation of C. cyphergaster and I. microcerus and reinforce the idea that their cohabitation is based on conflict-avoiding strategies.
Towards the classification of static vacuum spacetimes with negative cosmological constant

We present a systematic study of static solutions of the vacuum Einstein equations with negative cosmological constant which asymptotically approach the generalized Kottler (“Schwarzschild–anti-de Sitter”) solution, within (mainly) a conformal framework. We show connectedness of conformal infinity for appropriately regular such spacetimes. We give an explicit expression for the Hamiltonian mass of the (not necessarily static) metrics within the class considered; in the static case we show that they have a finite and well-defined Hawking mass. We prove inequalities relating the mass and the horizon area of the (static) metrics considered to those of appropriate reference generalized Kottler metrics. Those inequalities yield an inequality which is opposite to the conjectured generalized Penrose inequality. They can thus be used to prove a uniqueness theorem for the generalized Kottler black holes if the generalized Penrose inequality can be established.
Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide

Significance Depression is a seriously disabling disorder, twice as common in women as in men. Lack of efficacy of existing pharmacotherapies in subsets of patients has led to an intensive search for new targets for antidepressant development, including receptors for neuropeptides such as galanin (GAL). In this study, we explore GAL and its three receptors, GAL1–3, comparing postmortem brain regions from depressed suicide patients and controls. Using quantitative PCR and bisulfite pyrosequencing, we report significant changes in the transcript and DNA methylation levels of GAL and galanin receptor 3 (GALR3) in the locus coeruleus and dorsal raphe nucleus, two regions important for mood regulation. Our findings suggest GAL3 involvement in depressive disorder, making it a possible drug target for this disease. Major depressive disorder (MDD) is a substantial burden to patients, families, and society, but many patients cannot be treated adequately. Rodent experiments suggest that the neuropeptide galanin (GAL) and its three G protein-coupled receptors, GAL1–3, are involved in mood regulation. To explore the translational potential of these results, we assessed the transcript levels (by quantitative PCR), DNA methylation status (by bisulfite pyrosequencing), and GAL peptide by RIA of the GAL system in postmortem brains from depressed persons who had committed suicide and controls. Transcripts for all four members were detected and showed marked regional variations, GAL and galanin receptor 1 (GALR1) being most abundant. Striking increases in GAL and GALR3 mRNA levels, especially in the noradrenergic locus coeruleus and the dorsal raphe nucleus, in parallel with decreased DNA methylation, were found in both male and female suicide subjects as compared with controls. In contrast, GAL and GALR3 transcript levels were decreased, GALR1 was increased, and DNA methylation was increased in the dorsolateral prefrontal cortex of male suicide subjects, however, there were no changes in the anterior cingulate cortex. Thus, GAL and its receptor GALR3 are differentially methylated and expressed in brains of MDD subjects in a region- and sex-specific manner. Such an epigenetic modification in GALR3, a hyperpolarizing receptor, might contribute to the dysregulation of noradrenergic and serotonergic neurons implicated in the pathogenesis of MDD. Thus, one may speculate that a GAL3 antagonist could have antidepressant properties by disinhibiting the firing of these neurons, resulting in increased release of noradrenaline and serotonin in forebrain areas involved in mood regulation.
Impression creep behavior of SiC particle-MoSi_2 composites

Using a cylindrical indenter (or punch), the impression creep behavior of MoSi_2-SiC composites containing 0–40% SiC by volume, was characterized at 1000–1200 °C, 258–362 MPa punch pressure. Through finite element modeling, an equation that depends on the material stress exponent was derived that converts the stress distribution beneath the punch to an effective compressive stress. Using this relationship, direct comparisons were made between impression and compressive creep studies. Under certain conditions, compressive creep and impression creep measurements yield comparable results after correcting for effective stresses and strain rates beneath the punch. However, rate-controlling mechanisms may be quite different under the two stressing conditions, in which case impression creep data should not be used to predict compressive creep behavior. The addition of SiC affects the impression creep behavior of MoSi_2 in a complex manner by pinning grain boundaries during pressing, thus leading to smaller MoSi_2 grains and by obstructing or altering both dislocation motion and grain boundary sliding.
Does the low FODMAP diet improve symptoms of radiation-induced enteropathy? A pilot study

Abstract Rationale: Patients with radiation-induced enteropathy (RE) after cancer treatment show similar symptoms as patients with irritable bowel syndrome (IBS). The low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet (LFD) is a widespread management strategy for IBS. We aimed to investigate if there may be a positive effect of LFD on symptoms and health-related quality of life (HRQOL) in patients with RE. Methods: In an open non-controlled pilot study, 11 patients (all female) with RE-related IBS symptoms were recruited largely based on own initiative. All followed LFD for four weeks. IBS Severity Scoring System (IBS-SSS) and IBS Symptom Questionnaire (IBS-SQ) were used to assess symptoms. Short Form Nepean Dyspepsia Index (SF-NDI) and 12-item Short Form Health Survey (SF-12) evaluated HRQOL. A three day food record was used to estimate baseline intake of FODMAPs and to reveal dietary changes. Results: FODMAP intake was successfully reduced, although LFD was found a burdensome intervention. IBS symptoms improved significantly based on mean total score of IBS-SSS and IBS-SQ, which changed from 310.2 ± 60.7 to 171.4 ± 107.2 (p = .001) and 27.4 ± 4.1 to 15.7 ± 10.1 (p = .002). HRQOL improved based on SF-NDI total score (30.5 ± 9.4 to 18.3 ± 8.2, p = .001) and based on mental (p = .047) and physical (p = .134) score of SF-12. Main additional dietary changes were reduced intake of energy, carbohydrates, and fiber. Conclusion: Our findings from this small-scaled pilot study indicate that the LFD may alleviate symptoms and improve HRQOL in patients with RE. Further controlled studies with larger sample size should be conducted to verify our results and hopefully enable implementation of LFD as a future part of the management strategy for RE.
ALICE's adventures in cultural computing

In the paradigm of cultural computing, different cultures need different approaches to address the cultural determinants that strongly influences our way of thinking, feeling and worldview in general. For the western culture, our answer to this need is an artistic and interactive installation (ALICE) based on the narrative 'Alice's Adventures in Wonderland'. To address the western culture characteristics highlighted in the narrative, six stages were selected and implemented as an interactive experience. From start to end, the user undergoes an immersive environment that integrates embodied and virtual agents, real and nature mimicking, and both virtual and augmented reality. Every stage challenges the hardware and software design to provide the intended experience, which at the overall system level yet have to be seamlessly integrated. A distributed and multi-layered architecture is designed to accommodate this need. After several pilot tests, the installation is ready as a cultural computing platform for the experiments that address the western cultural determinants.
HER 2 status in molecular apocrine breast cancer : associations with clinical , pathological , and molecular features

Molecular apocrine breast cancer (MABC) is a distinct subtype of breast cancer. The purpose of this study was to investigate the relationship between HER2 status and clinicopathologic characteristics of MABCs from Chinese Han cohort. A cohort of 90 MABC patients were enrolled. Immunohistochemical method was performed to analyze the molecular expression, and the human epidermal growth factor receptor 2 (HER2) amplification was verified by fluorescence in situ hybridization (FISH). By studying these 90 MABC cases, the majority of studied patients were premenopausal young women (median age 48 yr) with high grade tumors. We also found that MABCs had high positive expression rates of HER2, CK8, CD44, CD166, p53 and BRCA1, the elevated Ki-67 labeling index, and favorable prognosis. There was a significantly higher incidence of lymph node metastasis and lower CD166 positive rate in HER2-negative patients compared to HER2-positive patients (54.5% vs. 37.0%, P = 0.044 and 72.7% vs. 91.3%, P = 0.021, respectively). The CK5/6 and EGFR expression rates were significant higher in HER2-negative cases than in HER2-positive cases, suggesting that there is overlap between MABC with HER2-negative phenotype and basal-like breast cancer. In addition, HER2 positive was found to be significantly associated a poor overall survival in MABCs. In conclusion, HER2 are highly expressed, and HER2 positivity could be considered as a significant biomarker of poor prognosis in MABC. The results also suggest that a subtype tumor with distinct patterns of molecule expression depending on HER2 status presented in MABC.
Relaxed Stability and Performance Conditions for Takagi–Sugeno Fuzzy Systems With Knowledge on Membership Function Overlap

This correspondence presents a relaxation of some earlier linear matrix inequality (LMI) conditions, which allow setting up less conservative stability or performance conditions for Takagi-Sugeno fuzzy models. Unlike the previous literature, this correspondence takes into account the knowledge of the membership functions' shape by considering bounds on them and their cross products (interpreted as an overlap measure), introducing auxiliary LMI variables. Numerical examples illustrate the achieved improvements
icenReg: Regression Models for Interval Censored Data in R

The non-parametric maximum likelihood estimator and semi-parametric regression models are fundamental estimators for interval censored data, along with standard fullyparametric regression models. The R package icenReg is introduced which contains fast, reliable algorithms for fitting these models. In addition, the package contains functions for imputation of the censored response variables and diagnostics of both regression effects and baseline distribution.
DEVELOPMENT OF PROCESS TECHNOLOGY FOR PREPARATION OF BANANA BEVERAGES

The present investigation entitles "development of process technology for preparation of banana beverages" was undertaken with the object to develop the process technology and evaluate the product for its shelf life. Basically three types of beverages were prepared viz; banana beverages, fermented banana beverages and fermented enzyme treated banana beverages by manipulating the ratio of banana pulp, water and sorghum flour. Fresh prepared beverages were subjected for physico-chemical analysis and sensory evaluation. The beverages were then filled in glass bottles and stored in a refrigerator at 5-7° C for 15 days. After 15 days all the beverages were again analysed for physicochemical changes and also evaluated by the panel of six judges on nine-point hedonic scale. All the samples stored have shown the significant variation in major physico-chemical properties. In the preparations like viscosity, titrable acidity, reducing sugar, total sugar, optical density, alcohol content and pellet per cent were found to have been changed significantly where as the other properties like pH and total soluble solids did not show any significant change. The data on sensory evaluation of all the beverages also show some deterioration in the quality as indicated by the scores given to the samples. Out of 21 different types of beverages, 1:4 ratio of banana beverages, 1:4:0.83 ratio of fermented banana beverages and 1:4:0.83 ratio of fermented amylase extract enzyme banana beverages were found to have been accepted highly after 15 days storage period. The beverage 1:4:0.83 was found to be the best among all upon sensory evaluation after 15 days storage. However, the beverages could be stored safely at 5-7° C for about 15 days without any appreciable deterioration in the quality. It can be concluded that 1:4:0.83 (Pulp:Water:Sorghum flour) ratio of fermented banana beverage was found to be the best on the basis of cost, overall acceptability and other physico-chemical properties.
Specialized impulse conduction pathway in the alligator heart

Mammals and birds have a specialized cardiac atrioventricular conduction system enabling rapid activation of both ventricles. This system may have evolved together with high heart rates to support their endothermic state (warm-bloodedness) and is seemingly lacking in ectothermic vertebrates from which first mammals then birds independently evolved. Here, we studied the conduction system in crocodiles (Alligator mississippiensis), the only ectothermic vertebrates with a full ventricular septum. We identified homologues of mammalian conduction system markers (Tbx3-Tbx5, Scn5a, Gja5, Nppa-Nppb) and show the presence of a functional atrioventricular bundle. The ventricular Purkinje network, however, was absent and slow ventricular conduction relied on trabecular myocardium, as it does in other ectothermic vertebrates. We propose the evolution of the atrioventricular bundle followed full ventricular septum formation prior to the development of high heart rates and endothermy. In contrast, the evolution of the ventricular Purkinje network is strongly associated with high heart rates and endothermy.
Carboxyl of Poly(D,L-lactide-co-glycolide) Nanoparticles of Perfluorooctyl Bromide for Ultrasonic Imaging of Tumor

Perfluorooctyl bromide (PFOB) enclosed nanoparticles (NPs) as ultrasonic contrasts have shown promising results in the recent years. However, NPs display poor contrast enhancement in vivo. In this work, we used the copolymers poly(lactide-co-glycolide) carboxylic acid (PLGA-COOH) and poly(lactide-co- glycolide) poly(ethylene glycol) carboxylic acid (PLGA-PEG-COOH) as a shell to encapsulate PFOB to prepare a nanoultrasonic contrast agent. The NPs were small and uniform (210.6 ± 2.9 nm with a polydispersity index of 0.129 ± 0.016) with a complete shell nuclear structure under the transmission electron microscopy (TEM). In vitro, when concentration of NPs was ≥10 mg/ml and clinical diagnostic frequency was ≥9 MHz, NPs produced intensive enhancement of ultrasonic gray-scale signals. NPs could produce stable and obvious gray enhancement with high mechanical index (MI) (MI > 0.6). In vivo, the NPs offered good ultrasound enhancement in tumor after more than 24 h and optical imaging also indicated that NPs were mainly located at tumor site. Subsequent analysis confirmed that large accumulation of fluorescence was observed in the frozen section of the tumor tissue. All these results caused the conclusion that NPs encapsulated PFOB has achieved tumor-selective imaging in vivo.
A functional variant in ST2 gene is associated with risk of hypertension via interfering MiR‐202‐3p

Recent studies have suggested that interleukin 1 receptor‐like 1 (ST2) plays a critical role in pathogenesis of several cardiovascular disease conditions. In this study, we examined association of 13 single nucleotide polymorphisms (SNPs) of ST2 gene with essential hypertension (EH) risk in 1151 patients with EH and 1135 controls. Our study showed that variants rs11685424, rs12999364 and rs3821204 are highly associated with an increase in risk of EH, while rs6543116 is associated with a decrease risk of EH. Notably, in silico analyses suggested the G>C change of rs3821204, which located within the 3′UTR of soluble ST2 mRNA, disrupted a putative binding site for miR202‐3p. Functional analyses suggested that miR‐202‐3p significantly decreased soluble ST2‐G mRNA stability and inhibited its endogenous expression. Furthermore, we found increased plasma‐soluble ST2 (sST2) level was highly associated with CC genotype of rs3821204 in vivo. Taken together, our findings provide the first evidence that genetic variants in ST2 gene are associated with EH risk and variant rs3821204 may influence the development of EH by controlling sST2 expression.
Effects of Combining 2 Weeks of Passive Sensory Stimulation with Active Hand Motor Training in Healthy Adults

The gold standard to acquire motor skills is through intensive training and practicing. Recent studies have demonstrated that behavioral gains can also be acquired by mere exposure to repetitive sensory stimulation to drive the plasticity processes. Single application of repetitive electric stimulation (rES) of the fingers has been shown to improve tactile perception in young adults as well as sensorimotor performance in healthy elderly individuals. The combination of repetitive motor training with a preceding rES has not been reported yet. In addition, the impact of such a training on somatosensory tactile and spatial sensitivity as well as on somatosensory cortical activation remains elusive. Therefore, we tested 15 right-handed participants who underwent repetitive electric stimulation of all finger tips of the left hand for 20 minutes prior to one hour of motor training of the left hand over the period of two weeks. Overall, participants substantially improved the motor performance of the left trained hand by 34%, but also showed a relevant transfer to the untrained right hand by 24%. Baseline ipsilateral activation fMRI-magnitude in BA 1 to sensory index finger stimulation predicted training outcome for somatosensory guided movements: those who showed higher ipsilateral activation were those who did profit less from training. Improvement of spatial tactile discrimination was positively associated with gains in pinch grip velocity. Overall, a combination of priming rES and repetitive motor training is capable to induce motor and somatosensory performance increase and representation changes in BA1 in healthy young subjects.
RAMON: Region-Aware Memory Controller

Recent implementations of heterogeneous multicore systems [central processing unit (CPU), graphics processing unit (GPU), and hybrid] address the issue of communication latency between CPU and GPU memory systems by merging these two, so that they can share the same memory address space. In recent years, the combination of the escalation in the number of cores with the rise in memory-intensive applications has significantly increased bandwidth (Bw) needs in both homogeneous and heterogeneous systems. Since tasks assigned to CPU and/or GPU cores will have different Bw demands, a two-tier memory system is needed. Hence, in this paper, Region-Aware Memory cONtroller (RAMON) is proposed as a configurable memory system where different address space regions are able to be dedicated to a different number of memory controllers (MCs), concurrently to supply different amounts of Bw to a different number of cores, providing different levels of memory parallelism. By having different address space regions—simply regions, each with a different number of MCs to match its Bw needs, memory interference per region is reduced. Our findings show that RAMON is promising and improves Bw by a factor of 9 times for CPU regions, 14.1 times for GPU regions, and 4.5 times for combined heterogeneous regions.
Experimental and numerical simulation studies on diesel pool fire

Experimental studies are performed under different ventilation conditions to investigate the effect of ventilation on compartment fires. A compartment of size 4 m × 4 m × 4 m having a door of size 2 m × 1 m is used for experiments. The experiments are conducted with full door open and half door open conditions. Diesel, used as a fuel source, is placed in a pan of 40 cm diameter and 15 cm height, which is kept in the center of the compartment. During experiments a constant 12 cm height of the fuel is maintained above the pan bottom. The maximum heat release rate is found to be 100 kW and 115 kW in full door open and half door open experiments respectively. It is observed that the size of door opening affected the heat release rate, burning rate and thermal environment inside the compartment after the growth period of 800 s. The numerical simulation is also performed for full door open experiment using CFD code, Fire Dynamics Simulator (FDS, version 6.0.1) developed by NIST. Simulation is accomplished with the refinement of mesh size near the fire source; results from FDS closely match with the experimental results. Copyright © 2016 John Wiley & Sons, Ltd.
Systematics and the Origin of Species from the Viewpoint of a Zoologist

By reading, you can know the knowledge and things more, not only about what you get from people to people. Book will be more trusted. As this systematics and the origin of species from the viewpoint of a zoologist paperback, it will really give you the good idea to be successful. It is not only for you to be success in certain life you can be successful in everything. The success can be started by knowing the basic knowledge and do actions.