Miracle-dz/UniFAR-FTUs huggingface dataset:
Emotional labour profiles: Associations with key predictors and outcomes

ABSTRACT The present study examines how three emotional labour strategies (hiding feelings, faking emotions, and deep acting) combine within different profiles of workers among two samples characterised by different types and intensity of customer contact. In addition, this research investigates the role of perceived workload as well as perceived organisational support, supervisor support, and colleagues support in the prediction of profile membership. Finally, this research also documents the relation between emotional labour profiles and adaptive and maladaptive work outcomes (job satisfaction, work performance, emotional exhaustion, sleeping problems, psychological detachment, and counterproductive work behaviours). Latent profile analysis revealed three similar emotional labour profiles in both samples. Results also showed the most desirable levels on all outcomes to be associated with Profile 3 (Low Emotional Labor/Low Surface Acting and Moderate Deep Acting), followed by Profile 2 (Moderate Emotional Labor/Moderate Surface Acting and High Deep Acting) and Profile 1 (High Emotional Labor), with most comparisons being statistically significant in both samples. In contrast, a more diversified pattern of findings was observed in the prediction of profile membership. For instance, perceived colleagues support did not predict membership into any of the profiles, while supervisor support predicted an increased likelihood of membership into Profile 3 relative to Profiles 1 and 2.
An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogaster

RNA surveillance factors are involved in heterochromatin regulation in yeast and plants, but less is known about the possible roles of ribonucleases in the heterochromatin of animal cells. Here we show that RRP6, one of the catalytic subunits of the exosome, is necessary for silencing heterochromatic repeats in the genome of Drosophila melanogaster. We show that a fraction of RRP6 is associated with heterochromatin, and the analysis of the RRP6 interaction network revealed physical links between RRP6 and the heterochromatin factors HP1a, SU(VAR)3-9 and RPD3. Moreover, genome-wide studies of RRP6 occupancy in cells depleted of SU(VAR)3-9 demonstrated that SU(VAR)3-9 contributes to the tethering of RRP6 to a subset of heterochromatic loci. Depletion of the exosome ribonucleases RRP6 and DIS3 stabilizes heterochromatic transcripts derived from transposons and repetitive sequences, and renders the heterochromatin less compact, as shown by micrococcal nuclease and proximity-ligation assays. Such depletion also increases the amount of HP1a bound to heterochromatic transcripts. Taken together, our results suggest that SU(VAR)3-9 targets RRP6 to a subset of heterochromatic loci where RRP6 degrades chromatin-associated non-coding RNAs in a process that is necessary to maintain the packaging of the heterochromatin.
When the Family Is Opposed to Coming to Therapy: A Study on Outcomes and Therapeutic Alliance With Involuntary and Voluntary Clients

The purpose of this study was to explore the effects of alliance dimensions and involuntary versus voluntary referral status on the therapy outcomes in family therapy. The first and fourth sessions of 29 therapeutic processes with involuntary and voluntary families seen in family brief therapy were rated with the System for Observing Family Therapy Alliances (Friedlander, Escudero, & Heatherington, 2006). This instrument evaluates four dimensions of the therapeutic alliance (Engagement in the Therapeutic Process, Emotional Connection with the Therapist, Safety within the Therapeutic System, and Shared Sense of Purpose within the Family). The outcomes were measured with the Goal Attainment Scaling (Kiresuk, Smith, & Cardillo, 1994). The obtained results highlight two main conclusions: (a) There were no differences in the outcomes between involuntary and voluntary families and (b) in the fourth session only, there was a significant effect of “Safety within the therapeutic system” and “Shared purpose within the family” on the outcomes, namely, those alliance dimensions that are unique for conjoint therapy. Important clinical implications are discussed concerning the therapeutic work with involuntary families.
RFID Estimation With Blocker Tags

With the increasing popularization of radio frequency identification (RFID) technology in the retail and logistics industry, RFID privacy concern has attracted much attention, because a tag responds to queries from readers no matter they are authorized or not. An effective solution is to use a commercially available blocker tag that behaves as if a set of tags with known blocking IDs are present. However, the use of blocker tags makes the classical RFID estimation problem much more challenging, as some genuine tag IDs are covered by the blocker tag and some are not. In this paper, we propose RFID estimation scheme with blocker tags (REB), the first RFID estimation scheme with the presence of blocker tags. REB uses the framed slotted Aloha protocol specified in the EPC C1G2 standard. For each round of the Aloha protocol, REB first executes the protocol on the genuine tags and the blocker tag, and then virtually executes the protocol on the known blocking IDs using the same Aloha protocol parameters. REB conducts statistical inference from the two sets of responses and estimates the number of genuine tags. Rigorous theoretical analysis of parameter settings is proposed to guarantee the required estimation accuracy, meanwhile minimizing the time cost and energy cost of REB. We also reveal a fundamental tradeoff between the time cost and energy cost of REB, which can be flexibly adjusted by the users according to the practical requirements. Extensive experimental results reveal that REB significantly outperforms the state-of-the-art identification protocols in terms of both time efficiency and energy efficiency.
Determinants of Mobile Apps Success: Evidence from App Store Market

Mobile applications markets with App stores have introduced a new approach to define and sell software applications with access to a large body of heterogeneous consumer population. This research examines key seller- and App-level characteristics that impact success in an App store market. We tracked individual Apps and their presence in the top grossing 300 charts in Apple App Store and examined how factors at different levels affect the Apps’ survival in the top 300 charts. We used a generalized hierarchical modeling approach to measure sales performance, and confirmed the results with the use of a hazard model and a count regression model. We find that broadening App offerings across multiple categories is a key determinant that contributes to a higher probability of survival in the top charts. App-level attributes such as free App offers, high initial ranks, investment in less popular (less competitive) categories, continuous quality updates, and high volume and high user review scores have positive impacts on Apps’ sustainability. In general, each diversification decision across a category results in approximately a 15% increase in the presence of an App in the top charts. Survival rates for free Apps are up to two times more than that for paid Apps. Quality (feature) updates to Apps can contribute up to a three-fold improvement in survival rate as well. A key implication of the results is that sellers must utilize the natural segmentation in consumer tastes offered by the different categories to improve sales performance.
Effect of Iron Containing Supplements on Rats’ Dental Caries Progression

Objective: Iron deficiency is the most common form of malnutrition in developing countries. Iron containing supplements have been used effectively to solve this problem. In children, because of teeth staining after taking iron drops, parents have the idea that iron drops are the cause of tooth decay; therefore, they limit this vital supplement in their children’s diet. Hereby, we evaluate the histologic effect of iron containing supplements on tooth caries in rice rats with cariogenic or non-cariogenic diet. Materials and Methods: Twelve rats were selected and divided into four groups for this interventional experimental study. Four different types of dietary regimens were used for four months; group A, cariogenic diet with iron containing supplements; group B, cariogenic diet without iron containing supplements; group C, non-cariogenic diet with iron containing supplements; group D, non-cariogenic diet without iron containing supplements. After sacrificing the rats, 20-micron histological sections of their posterior teeth were prepared using the Ground Section method, then they were studied under polarized light microscopy. In order to compare the progression of caries in different samples, the depth of the lesions in the enamel was measured as three grades I, II and III. Results: The mean grade value of A, B, C and D groups were 1.61, 2.61, 1.37 and 1.80, respectively. Statistical analysis revealed that significantly fewer caries were seen in the group which had received iron containing supplements and cariogenic diet compared with cariogenic diet without iron supplements (p<0.05). Conclusion: Ferrous sulfate reduces the progression of dental caries in the cariogenic dietary regimen.
Conditions of the household and peridomicile and severe dengue: a case–control study in Brazil

Introduction The potential influence of high-vector-density environments where people are supposedly more exposed to mosquito bites may have a relation to the clinical severity of dengue fever, an association that has been poorly discussed in the literature. Objective This study aimed at analyzing the association between anthropic environmental factors, particularly those related to the conditions of domicile and peridomicile, and the occurrence of severe dengue cases during the 2008 epidemic in the state of Rio de Janeiro. Methods We conducted a retrospective case–control study with a sample of 88 severe patients aged 2–18. They were selected through chart review in four children's tertiary care centers. The 367 controls were neighbors of the cases, paired by age. Data were collected through interviews and systematic assessment of house conditions as well as peridomicile area conditions, and they were later analyzed by conditional logistic regression. Results The presence of three or more high-volume capacity containers, which were without a lid or were inadequately sealed (water tanks, wells, cisterns, cement tanks, and pools), was significantly more frequent in households with severe cases when compared with households of controls (OR=1.6; CI 95%=1.36–20.01; p=0.015). Discussion The presence of such larger reservoirs that could potentially produce more adult forms of the vector is consistent with a situation where people are more exposed to mosquito bites, and consequently are more prone to have multiple infections over a short period of time. Conclusion The emergence of severe dengue cases in a high-transmission context underpins the importance of constant vigilance and interventions in those types of reservoirs, which result from precarious household structures and irregular water supply services.
Functional coherence in domain interaction networks

MOTIVATION Extracting functional information from protein-protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature of data obtained from high-throughput screening. Typical proteins are composed of multiple domains, often regarded as their primary functional and structural units. Motivated by these considerations, domain-domain interactions (DDI) for network-based analyses have received significant recent attention. This article performs a formal comparative investigation of the relationship between functional coherence and topological proximity in PPI and DDI networks. Our investigation provides the necessary basis for continued and focused investigation of DDIs as abstractions for functional characterization and modularization of networks. RESULTS We investigate the problem of assessing the functional coherence of two biomolecules (or segments thereof) in a formal framework. We establish essential attributes of admissible measures of functional coherence, and demonstrate that existing, well-accepted measures are ill-suited to comparative analyses involving different entities (i.e. domains versus proteins). We propose a statistically motivated functional similarity measure that takes into account functional specificity as well as the distribution of functional attributes across entity groups to assess functional similarity in a statistically meaningful and biologically interpretable manner. Results on diverse data, including high-throughput and computationally predicted PPIs, as well as structural and computationally inferred DDIs for different organisms show that: (i) the relationship between functional similarity and network proximity is captured in a much more (biologically) intuitive manner by our measure, compared to existing measures and (ii) network proximity and functional similarity are significantly more correlated in DDI networks than in PPI networks, and that structurally determined DDIs provide better functional relevance as compared to computationally inferred DDIs.
Prospects for the Characterization and Confirmation of Transiting Exoplanets via the Rossiter-McLaughlin Effect

The Rossiter-McLaughlin (RM) effect is the distortion of stellar spectral lines that occurs during eclipses or transits, due to stellar rotation. We assess the future prospects for using the RM effect to measure the alignment of planetary orbits with the spin axes of their parent stars, and to confirm exoplanetary transits. We compute the achievable accuracy for the parameters of interest, in general and for the five known cases of transiting exoplanets with bright host stars. We determine the requirements for detecting the effects of differential rotation. For transiting planets with small masses or long periods (as will be detected by forthcoming satellite missions), the velocity anomaly produced by the RM effect can be much larger than the orbital velocity of the star. For a terrestrial planet in the habitable zone of a Sunlike star found by the Kepler mission, it will be difficult to use the RM effect to confirm transits with current instruments, but it still may be easier than measuring the spectroscopic orbit.
On Instruction Sets for Boolean Registers in Program Algebra

In previous work carried out in the setting of program algebra, including work in the area of instruction sequence size complexity, we chose instruction sets for Boolean registers that contain only instructions of a few of the possible kinds. In the current paper, we study instruction sequence size bounded functional completeness of all possible instruction sets for Boolean registers. We expect that the results of this study will turn out to be useful to adequately assess results of work that is concerned with lower bounds of instruction sequence size complexity.
Relative pay and job satisfaction: some new evidence

This paper investigates the determinants of job satisfaction using data from the National Educational Longitudinal Study. The determinants of interest include actual pay, relative pay, hours of work, job autonomy and several personal characteristics. We also investigate the determinants of satisfaction with pay conditional on a worker's satisfaction with other domains of job satisfaction, such as satisfaction with job security. We find that relative pay is statistically significant but that its effect on satisfaction with pay is relatively small. Job autonomy has a powerful influence on satisfaction with pay. So too does being black.
Writing SMART rehabilitation goals and achieving goal attainment scaling: a practical guide

Objective: To describe a practical method of setting personalized but specific goals in rehabilitation that also facilitates the use of goal attainment scaling. Background: Rehabilitation is a complex intervention requiring coordinated actions by a team, a process that depends upon setting interdisciplinary goals that are specific, clear and personal to the patient. Goal setting can take much time and still be vague. A practical and standardized method is needed for being specific. Method: A novel approach to writing specific, measurable, achievable, realistic/ relevant and timed (SMART) goals is developed here. Each goal can be built up by using up to four parts: the target activity, the support needed, quantification of performance and the time period to achieve the desired state. This method can be employed as part of goal attainment scaling and the other levels can be easily and quickly formulated by adding, deleting and/or changing one or more of the (sub)parts. Discussion: The success of goal setting and goal attainment scaling depends on the formulation of the goals. The method described here is a useful tool to standardize the writing of goals in rehabilitation. It saves time and simplifies the construction of goals that are sufficiently specific to be measurable.
Protective Effect of Folic Acid on Oxidative DNA Damage

AbstractAlthough previous reports have linked DNA damage with both transmissions across generations as well as our own survival, it is unknown how to reverse the lesion. Based on the data from a Randomized, Double-blind, Placebo Controlled Clinical Trial, this study aimed to assess the efficacy of folic acid supplementation (FAS) on DNA oxidative damage reversal.In this randomized clinical trial (RCT), a total of 450 participants were enrolled and randomly assigned to 3 groups to receive folic acid (FA) 0.4 mg/day (low-FA), 0.8 mg/day (high-FA), or placebo (control) for 8 weeks. The urinary 8-hydroxy-2’-deoxyguanosine (8-OHdG) and creatinine (Cr) concentration at pre- and post-FAS were measured with modified enzyme-linked immunosorbent assay (ELISA) and high-performance liquid chromatography (HPLC), respectively. A multivariate general linear model was applied to assess the individual effects of FAS and the joint effects between FAS and hypercholesterolemia on oxidative DNA damage improvement. This clinical trial was registered with ClinicalTrials.gov, number NCT02235948.Of the 438 subjects that received FA fortification or placebo, the median (first quartile, third quartile) of urinary 8-OHdG/Cr for placebo, low-FA, and high-FA groups were 58.19 (43.90, 82.26), 53.51 (38.97, 72.74), 54.73 (39.58, 76.63) ng/mg at baseline and 57.77 (44.35, 81.33), 51.73 (38.20, 71.30), and 50.65 (37.64, 76.17) ng/mg at the 56th day, respectively. A significant decrease of urinary 8-OHdG was observed after 56 days FA fortification (P < 0.001). Compared with the placebo, after adjusting for some potential confounding factors, including the baseline urinary 8-OHdG/Cr, the urinary 8-OHdG/Cr concentration significantly decreased after 56 days FAS [&bgr; (95% confidence interval) = −0.88 (−1.62, −0.14) and P = 0.020 for low-FA; and &bgr; (95% confidence interval) = −2.68 (−3.42, −1.94) and P < 0.001 for high-FA] in a dose-response fashion (Ptrend < 0.001). Test of interaction between hypercholesterolemia and FA supplementation on urinary 8-OHdG reduction was significant (P = 0.001). The present study demonstrates that FA fortification is independently linked to the reduction of urinary 8-OHdG/Cr in a dose-related pattern, which suggests that FA is beneficial to protect against oxidative damage to DNA. This effect is apparently stronger in those with hypercholesterolemia. The authors provide a new insight into the prevention and reversal of oxidative DNA damage.
Concussions From 9 Youth Organized Sports

Background: Youth sports programs are extremely popular throughout the United States, with children starting formal sports participation as young as 4 years. This places children at greater risk for concussions and other trauma. Purpose: To describe the epidemiology of concussions sustained during participation in 9 organized sports prior to participation in high school athletics. Methods: Over an 11-year span from January 2002 to December 2012, the authors reviewed the concussions sustained by athletes aged 4 to 13 years while playing basketball, baseball, football, gymnastics, hockey, lacrosse, soccer, softball, and wrestling, as evaluated in emergency departments (EDs) in the United States and captured by the National Electronic Injury Surveillance System (NEISS) database of the US Consumer Product Safety Commission. Study Design: Descriptive epidemiology study. Results: There were 4864 (national estimate [NE] = 117,845) youth athletes evaluated in NEISS EDs as sustaining concussions from 2002 to 2012. Except for the year 2007, concussion frequencies trended upward throughout the 11-year time frame as well as with increasing age. Loss of consciousness (LOC) occurred in 499 cases (NE, 12,129; 10%). Football had the highest frequency of concussions, with 2013 (NE, 51,220; 41%), followed by basketball, with 977 (NE, 22,099; 20%), and soccer, with 801 (NE, 18,916; 17%). The majority of concussions were treated in the outpatient setting, with 4444 (91.4%) patients being treated and released; 412 (9%) patients required admission and were found to have increased frequencies of LOC (n = 17; 18.0%) compared with LOC in the total group (n = 499, 10%). The total number of player-to-player injury mechanisms mirrored the total number of concussions by year, which increased throughout the 11-year span, except for the year 2007. Subgroup analysis of athletes aged 4 to 7 years demonstrated a difference in the mechanism of injury distribution, with a ball-to-head mechanism increase of 5% from 15% to 20% and a player-to–other object mechanism of injury increase by more than double to 13% compared with the entire cohort over the 11-year time frame. Conclusion: Within the 4- to 13-year age range, there were a significant number of young athletes who presented to EDs with concussion as a result of playing organized sports. The 4- to 7-year age group had a disproportionately higher player-to–other object mechanism of injury. Clinical Relevance: Younger children are more susceptible to long-term sequelae from head injuries, and therefore, improved systems of monitoring for these athletes are required to monitor the patterns of injury, identify risk factors, and develop evidence-based prevention programs.
Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing

Characterizing the genetic programs that specify development and evolution of the cerebral cortex is a central challenge in neuroscience. Stem cells in the transient embryonic ventricular and subventricular zones generate neurons that migrate across the intermediate zone to the overlying cortical plate, where they differentiate and form the neocortex. It is clear that not one but a multitude of molecular pathways are necessary to progress through each cellular milestone, yet the underlying transcriptional programs remain unknown. Here, we apply differential transcriptome analysis on microscopically isolated cell populations, to define five transcriptional programs that represent each transient embryonic zone and the progression between these zones. The five transcriptional programs contain largely uncharacterized genes in addition to transcripts necessary for stem cell maintenance, neurogenesis, migration, and differentiation. Additionally, we found intergenic transcriptionally active regions that possibly encode unique zone-specific transcripts. Finally, we present a high-resolution transcriptome map of transient zones in the embryonic mouse forebrain.