Miracle-dz/UniFAR-FTUs huggingface dataset:
Embedding Wellbeing Knowledge and Practice into Teacher Education: building emotional resilience

Trainee teachers’ self-awareness and their developing professional identity are of crucial importance as they enter complex school environments in a role which makes intense demands of them, both personally and professionally. To enable a smooth transition into school life, trainee teachers need to be able to critically reflect on their strengths, core values and performance. This study researched the impact of three workshops covering professional identity, teaching values and psychological models during the teacher training year. A mixed methods approach was employed: a questionnaire ascertained feedback on each workshop attended (October; February and May (N=38, 35, 31 respectively) and a final group interview (N=12) followed-up the workshops undertaken. Key findings indicated: the teacher ‘daily diary’ was extremely useful, reassurance of work-life balance beneficial, psychology shared very helpful (e.g. Maslow’s work; Erskine’s relational needs; Rogers’ core conditions). Key factors regularly used by trainee teachers were: using their planner, making time for others and trying to incorporate a work-life balance. The main conclusions reveal the essential requirement of trainee teachers being able to self-reflect, to organise their time and to have the capability to develop strategies to address the challenges they meet during their time in school.
FREQUENCY ANALYSIS OF PHYSIOLOGICAL AND NEUROTIC TREMORS

It seems reasonable to assert that the diagnostic distinctions between the common organic causes of tremor emerged clearly during the sixties of the last century, and that this was partly due to the work of Charcot and his pupils. At this time also the Marey tambour (Marey, 1868) came into widespread use. These two circumstances seem to have been responsible for the first attempts to study graphical records of tremor by Charcot's pupils, and it was in turn upon these experimental results that Charcot based his later teaching (Charcot, 1888, 1889) on tremors. He divided the non-intentional tremors into three main groups: (1) Slow, 4-5 per second (Parkinsonian); (2) intermediate, 5A-6 per second (hysterical); (3) rapid or vibratory, 8-9 per second (Basedow's disease, alcoholism, general paralysis of the insane). As far as the tremors of neurosis are concerned, Charcot's later pupils (e.g., Dutil, 1891) were able to show that this scheme was an oversimplification and that hysterical tremors, for example, were often vibratory in type. Since then there has been little advance in our knowledge of the neurotic tremors. Most clinicians have simply divided neurotic tremors into the categories of coarse and fine, corresponding with the intermediate and the vibratory groups respectively. The coarse tremors are commonly associated with hysteria and are often, on the basis of wartime experience, held to carry a better prognosis than the fine tremors, which are commonly associated with anxiety and other neuroses (Mott, 1919). Meanwhile Schafer (1886) had demonstrated a 10-per-second rhythm in the normal human voluntary myogram, and a majority of subsequent authors have found this to be the predominant frequency of physiological tremor. Theories sometimes held to account for this family of physiological and neurotic tremors may be summarized as follows: (a) That the rhythm is determined by the mechanical properties of the muscle or of the muscle twitch; (b) that it is due to the delayed self-correction inherent in the stretch reflex; (c) that there is some intrinsic rhythmical propensity at the spinal level; and (d) that the rhythm is due to driving by higher centres, e.g., the motor cortex. It must be observed that the relationship between " physiological ", emotional, thermal, and neurotic trembling has never been precisely defined. It is therefore not usually possible to be clear as to exactly which type or types of tremor these theories are held to explain. This paper describes the frequency analysis of normal and neurotic tremors, the results of which suggest a common physiological basis. The definition of a neurotic tremor used in this paper is a tremor occurring in a person suffering from neurosis. It will be seen that from the point of view of the harmonic components of neurotic tremors, they are largely an exaggerated form of physiological tremor. The above definition is therefore a logical necessity.
The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disorders.

BACKGROUND The association between mood disorders and personality disorders (PDs) is complicated clinically, conceptually, and neurobiologically. There is a need for recommendations to assist clinicians in treating these frequently encountered patients. METHODS The literature was reviewed with the purpose of identifying clinically relevant themes. MedLine searches were supplemented with manual review of the references in relevant papers. From the extant evidence, consensus-based recommendations for clinical practice were developed. RESULTS Key issues were identified with regards to the overlap of PDs and mood disorders, including whether certain personality features predispose to mood disorders, whether PDs can reliably be recognized if there is an Axis I disorder present, whether personality disturbances arise as a consequence or are a forme fruste of mood disorders, and whether personality traits or disorders modify treatment responsiveness and outcome of mood disorders. CONCLUSION This paper describes consensus-based clinical recommendations that arise from a consideration of how signals from the literature can impact clinical practice in the treatment of patients with comorbid mood and personality pathology. Additional treatment studies of patients with the comorbid conditions are required to further inform clinical practice.
Self-Esteem and Self-Consistency: A Theoretical and Empirical Link Between Two Primary Motivations

This study investigates the relationship between two primary motivational components of the self-concept: self-esteem and self-consistency. Research has shown that high self-e.steem is associated with greater consistency. Developed from theories ofthe self-concept, a structural model relating these two constructs was posited such that; (1) self-esteem is causally prior to self-consistency and (2) the effect of self-esteem is (at least partially) mediated hy other components of the self-concept (self-consciousness. the tendency to fantasize and the tendency to present a false front by hiding one's feelings). An analysis of covariance structures was applied to a structural equation model wilh unobserved variables, using data from a sample of youth (ages 8-19). Mulligroup analyses ofthe sample broken down by developmental stage (pre-. early and late adolescence) revealed that the direct effect of self-esteem on self-consiste ncy and the mediational properties of the other self-concept components varied across age. These differences are interpreted in tight of theories of cognitive and social development.
Attractors for noncompact nonautonomous systems via energy equations

An extension to the nonautonomous case of the energy equation method for proving the existence of attractors for noncompact systems is presented. A suitable gen- eralization of the asymptotic compactness property to the nonautonomous case, termed uniform asymptotic compactness, is given, and conditions on the energy equation associ- ated with an abstract class of equations that assure the uniform asymptotic compactness are obtained. This general formulation is then applied to a nonautonomous Navier-Stokes system on an infinite channel past an obstacle, with time-dependent forcing and boundary conditions, and to a nonautonomous, weakly damped, forced Korteweg-de Vries equation on the real line.
Investigation on Huntington's disease in the Canadian Prairies

The reproductive performance of 157 patients with Huntington's disease, their 170 normal siblings and 150 matched unrelated controls is presented. Comparison with the general Canadian Prairie population in the appropriate age group is undertaken. Patients with Huntington's disease are not only more fecund than their unaffected sibs but also out‐reproduce unrelated normal controls and members of the general population of corresponding age. Their fitness is thus estimated to be 1.14. Should the present reproductive pattern continue, the allele for Huntington's disease will double its frequency with consequent doubling of the prevalence of the disorder in six generations or approximately 150 years' time.
CANADIAN YOUTH VOLUNTEERING ABROAD: RETHINKING ISSUES OF POWER AND PRIVILEGE

This paper discusses the role of institutions in the ethical engagement of Canadian youth volunteers abroad. In recent years, researchers and practitioners in the international field have questioned the ethics of volunteering as part of development, with scrutiny on who actually benefits from volunteering initiatives. Since the 1960s, over 65,000 young Canadians have participated in volunteer abroad programs (Tiessen, 2008), and criticism has increased towards youth volunteers going overseas to fulfill their aspirations to “change the world”. This study considered how complex social relations and institutional structures in international development have shaped the issues of power and privilege of the young person’s experience in volunteering. The research used Institutional Ethnography (IE) as a method of inquiry, and mapped out the social relations between the experiences of seven former youth volunteers and field staff, and their organizations. Westheimer and Kahne’s Active Citizenship and Dei’s Anti-Racism theories were proposed as frameworks to examine the presence of equity in youth volunteer programs.
PD Disease State Assessment in Naturalistic Environments Using Deep Learning

Management of Parkinson's Disease (PD) could be improved significantly if reliable, objective information about fluctuations in disease severity can be obtained in ecologically valid surroundings such as the private home. Although automatic assessment in PD has been studied extensively, so far no approach has been devised that is useful for clinical practice. Analysis approaches common for the field lack the capability of exploiting data from realistic environments, which represents a major barrier towards practical assessment systems. The very unreliable and infrequent labelling of ambiguous, low resolution movement data collected in such environments represents a very challenging analysis setting, where advances would have significant societal impact in our ageing population. In this work we propose an assessment system that abides practical usability constraints and applies deep learning to differentiate disease state in data collected in naturalistic settings. Based on a large data-set collected from 34 people with PD we illustrate that deep learning outperforms other approaches in generalisation performance, despite the unreliable labelling characteristic for this problem setting, and how such systems could improve current clinical practice.
Saccharomyces cerevisiae null mutants in glucose phosphorylation: metabolism and invertase expression.

A congenic series of Saccharomyces cerevisiae strains has been constructed which carry, in all combinations, null mutations in the three genes for glucose phosphorylation: HXK1, HXK2 and GLK1, coding hexokinase 1 (also called PI or A), hexokinase 2 (PII or B), and glucokinase, respectively: i.e., eight strains, all of which grow on glucose except for the triple mutant. All or several of the strains were characterized in their steady state batch growth with 0.2% or 2% glucose, in aerobic as well as respiration-inhibited conditions, with respect to growth rate, yield, and ethanol formation. Glucose flux values were generally similar for different strains and conditions, provided they contained either hexokinase 1 or hexokinase 2. And their aerobic growth, as known for wild type, was largely fermentative with ca. 1.5 mol ethanol made per mol glucose used. The strain lacking both hexokinases and containing glucokinase was an exception in having reduced flux, a result fitting with its maximal rate of glucose phosphorylation in vitro. Aerobic growth of even the latter strain was largely fermentative (ca. 1 mol ethanol per mol glucose). Invertase expression was determined for a variety of media. All strains with HXK2 showed repression in growth on glucose and the others did not. Derepression in the wild-type strain occurred at ca. 1 mM glucose. The metabolic data do not support- or disprove-a model with HXK2 having only a secondary role in catabolite repression related to more rapid metabolism.
TaqMan 5′-Nuclease Human Immunodeficiency Virus Type 1 PCR Assay with Phage-Packaged Competitive Internal Control for High-Throughput Blood Donor Screening

ABSTRACT Screening of blood donors for human immunodeficiency virus type 1 (HIV-1) infection by PCR permits the earlier diagnosis of HIV-1 infection compared with that by serologic assays. We have established a high-throughput reverse transcription (RT)-PCR assay based on 5′-nuclease PCR. By in-tube detection of HIV-1 RNA with a fluorogenic probe, the 5′-nuclease PCR technology (TaqMan PCR) eliminates the risk of carryover contamination, a major problem in PCR testing. We outline the development and evaluation of the PCR assay from a technical point of view. A one-step RT-PCR that targets thegag genes of all known HIV-1 group M isolates was developed. An internal control RNA detectable with a heterologous 5′-nuclease probe was derived from the viral target cDNA and was packaged into MS2 coliphages (Armored RNA). Because the RNA was protected against digestion with RNase, it could be spiked into patient plasma to control the complete sample preparation and amplification process. The assay detected 831 HIV-1 type B genome equivalents per ml of native plasma (95% confidence interval [CI], 759 to 936 HIV-1 B genome equivalents per ml) with a ≥95% probability of a positive result, as determined by probit regression analysis. A detection limit of 1,195 genome equivalents per ml of (individual) donor plasma (95% CI, 1,014 to 1,470 genome equivalents per ml of plasma pooled from individuals) was achieved when 96 samples were pooled and enriched by centrifugation. Up to 4,000 plasma samples per PCR run were tested in a 3-month trial period. Although data from the present pilot feasibility study will have to be complemented by a large clinical validation study, the assay is a promising approach to the high-throughput screening of blood donors and is the first noncommercial test for high-throughput screening for HIV-1.
Blood groups, myocardial infarction and angina pectoris among 10,000 adult males.

Abstract A five-year prospective investigation of 10,000 Israeli male government employees 40 years of age and over was conducted as part of the Israeli Ischemic Heart Disease Project. The six areas of birth represented were Eastern Europe, Central Europe, Southeastern Europe, Israel, Asia, and North Africa. Subjects with blood Groups A1, B, and A1B tended to have higher incidence rates of myocardial infarction than those with other blood groups. High rates were also noted in A1 and B subjects for angina pectoris. Subjects in blood Group O tended to have lower rates of infarction and angina pectoris than those of other groups, but the differences were not significant. Among the Rhesus, MN, Kell, Duffy and Kidd blood groups, subjects with Kidd negative (JKa-) had the highest rates for both myocardial infarction and angina pectoris. When this group was added to the ABO system, the combinations of A1Jka-, BJka- and, particularly, A1BJka-, had very high incidence rates.
Public Ideology, Minority Threat, and Felony Collateral Sanctions

Federal and state felony collateral sanctions directly impact the opportunities and resources available to ex-felons and in turn their ability to successfully reenter society after conviction and possible incarceration. Because felony collateral sanctions vary greatly from state to state, we offer a state-level analysis of factors that produce differences in collateral sanctions levels adopted by U.S. states. Religion, political climate, and minority threat explanations have been linked to criminal penalty severity; however, no one to date has applied these explanations to felony collateral sanctions besides felony disenfranchisement at the macro level. With zero-truncated Poisson (ZTP) procedures, this study examines whether religion, political climate, and minority threat explanations result in states’ adopting greater collateral sanctions against convicted felons. Our research reveals that conservative climate, religiosity, and racial threat, but not ethnic threat or punitiveness, significantly affect state-level collateral sanctions. States with large minority and conservative populations are more likely to have more stigmatizing collateral sanction that can affect recidivism. We find that race rather than ethnicity is an important predictor of the collateral sanctions levels that states adopt; however, public ideology in the form of conservatism and religiosity has a greater effect on collateral sanctions. Policy implications are discussed.
Plasminogen activator inhibitor-1, free fatty acids, and insulin resistance in patients with myocardial infarction

Background Insulin resistance is known to be a common feature of type 2 diabetes mellitus and is regarded as an important mechanism in the pathogenesis of this disease. The key pathogenetic mechanisms of insulin resistance progression are free fatty acids metabolism impairment and enhanced activity of plasminogen activator inhibitor 1. Both free fatty acids and plasminogen activator inhibitor 1 are recognized as risk factors for coronary heart disease. Methods The patients were divided into two groups: group 1 included 65 non-diabetic myocardial infarction patients and group 2 enrolled 60 diabetic myocardial infarction patients. The control group consisted of 30 sex- and age-matched volunteers. The concentration of serum free fatty acids, glucose, C-peptide, and insulin were measured on the 1st and 12th days of the study. All the patients had their postprandial glycemia, insulin, and C-peptide concentrations measured 2 hours after a standard carbohydrate breakfast containing 360 kcal (protein 20 g, carbohydrate 57 g, and fat 9 g). Results Free fatty acids levels in group 1 and in group 2 exceeded the control group values by 7-fold and 11-fold, respectively. Plasminogen activator inhibitor 1 concentration was 2.5-fold higher in group 1 and 4.6-fold higher in group 2 compared to the control group on the 1st day from the myocardial infarction onset. In addition, plasminogen activator inhibitor 1 concentration was significantly reduced in both groups on the 12th day from the myocardial infarction onset; however, it did not achieve the control group values. Conclusion Increased postprandial glucose level, insulinemia, and elevated levels of free fatty acids and plasminogen activator inhibitor are associated with myocardial infarction-associated progression of insulin resistance. However, insulin resistance metabolic markers are of great predictive capacity in the assessment of risk of acute coronary events.
ANTIGENIC CHARACTERIZATION OF PORCINE METACESTODES

The antigenic profiles of bladder worms collected from pigs slaughtered at Mumbai abattoir were studied by protein estimation, SDS-PAGE mobility and column chromatographic pattern of crude fluid antigens. The average protein content of fluid from Cysticercus cellulosae, Cysticercus tenuicollis and hydatid cysts was found to be 69.42, 37.3 and 67.2 mg%, respectively. SDS-PAGE analysis of crude fluid antigens of Cysticercus cellulosae, Cysticercus tenuicollis and hydatid cysts revealed 13, 12 and eight protein moieties with their molecular weights ranging from 200 to 14, 312 to 24 and 272 to 38 kDa, respectively. Crude fluid antigens of the three types of porcine metacestodes when subjected to column chromatography through Sephadex G 200, demonstrated two distinct peaks each. The cross reactivity studies to identify the parasite specific component demonstrated that Peak II antigen of Cysticercus cellulosae and Peak I antigen of Cysticercus tenuicollis and hydatid fluid were more specific to their respective metacestode as revealed by less number of cross reactivity with heterologous antisera as compared to that with Peak I antigen of Cysticercus cellulosae and Peak II antigen of Cysticercus tenuicollis and hydatid fluid, respectively. Thus Peak II antigen of Cysticercus cellulosae and Peak I antigen of Cysticercus tenuicollis and hydatid fluid can be exploited further for improving the immunodiagnostic efficacy of porcine metacestode infections.
New static compaction techniques of test sequences for sequential circuits

This paper describes an algorithm for compacting the Test Sequences generated by an ATPG tool without reducing the number of faults they detect. The algorithm is based on re-ordering the sequences so that some of them can be shortened and some others eliminated. The problem is NP-complete, and we adopt Genetic Algorithms to obtain optimal solutions with acceptable computational requirements. As it requires just one preliminary Fault Simulation experiment, the approach is much more efficient than others proposed before; experimental results gathered with Test Sets generated by different ATPG tools show that the method is able to reduce the size of the Test Set by a factor varying between 50% and 62%.
Autism spectrum disorders and autistic traits: A decade of new twin studies

Researchers continue to pursue a better understanding of the symptoms, comorbidities, and causes of autism spectrum disorders. In this article we review more than 30 twin studies of autism spectrum disorders (ASDs) and autistic traits published in the last decade that have contributed to this endeavor. These twin studies have reported on the heritability of autism spectrum disorders and autistic traits in different populations and using different measurement and age groups. These studies have also stimulated debate and new hypotheses regarding why ASDs show substantial symptom heterogeneity, and what causes their comorbidity with intellectual disability, language delay, and other psychiatric disorders such as ADHD. These studies also reveal that the etiology of autism and autistic traits assessed in the general population is more similar than different, which contributes to the question of where the boundary lies between autism and typical development. Recent findings regarding molecular genetic and environmental causes of autism are discussed in the relation to these twin studies. Lastly, methodological assumptions of the twin design are given consideration, as well as issues of measurement. Future research directions are suggested to ensure that this decade is as productive as the last in attempting to disentangle the causes of autism spectrum disorders. © 2011 Wiley‐Liss, Inc.