Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship of depressive symptoms to the impact of physical symptoms on functional status in women with heart failure.

BACKGROUND Among patients with heart failure, women have worse functional status than do men, but little research has focused on determining factors that influence functional status in either sex. OBJECTIVES To compare factors that influence functional status in men and women with heart failure and to test whether depressive symptoms mediate the relationship between physical symptoms and functional status. METHODS A cross-sectional, descriptive study design was used. A total of 231 patients, 133 men and 98 women, were recruited from an inpatient heart failure clinic in South Korea. Functional status (the Korean Activity Scale/Index), physical symptoms (the Symptom Status Questionnaire), depressive symptoms (the Beck Depression Inventory), and situational factors (living status, socioeconomic status) were measured. Hierarchical multiple regression and mediation analysis were used for data analysis. RESULTS Women (mean score, 24.5; SD, 17.3) had worse functional status than did men (mean score, 31.9; SD, 20.1; P = .004). Dyspnea on exertion (beta = -0.16), ankle swelling (beta = -0.19), fatigue (beta = -0.20), and depressive symptoms (beta = -0.19) were independently associated with functional status in women, whereas only dyspnea on exertion (beta = -0.30) influenced functional status of men in hierarchical multiple regression analysis. Mediation analysis indicated that depressive symptoms mediated the relationship between physical symptoms and functional status in women with heart failure, but not in men. CONCLUSIONS Distinct physical and psychological symptoms influence functional status in women with heart failure. A systematic multidimensional intervention may be required to target depressive symptoms to improve functional status in women with heart failure.
Co-Creation in Branding Through Social Commerce: The Role of Social Support, Relationship Quality and Privacy Concerns

Consumers have become increasingly empowered to exert influence on brands through online communities. Social media make consumers not only to be passive information users, but active content creators in the value creation process in online marketplaces. We examined social commerce constructs and their impact on brand development. Empirical data was collected via a questionnaire and analyzed using SEM-PLS. The results show that both relationship quality and social commerce constructs have positive effects on co-branding intention. Social commerce constructs and social support positively affect relationship quality, highlighting the stronger effect of social support on relationship quality. Social commerce constructs also positively affect social support and its most influence is on co-branding intention. Finally, this research confirms the moderating effect of privacy concern between social commerce constructs and co-branding. The contributions of this study provide new insights into marketing and brand management literature by proposing an initial model of social commerce.
Genome-Wide Characterization of the MADS-Box Gene Family in Radish (Raphanus sativus L.) and Assessment of Its Roles in Flowering and Floral Organogenesis

The MADS-box gene family is an important transcription factor (TF) family that is involved in various aspects of plant growth and development, especially flowering time and floral organogenesis. Although it has been reported in many plant species, the systematic identification and characterization of MADS-box TF family is still limited in radish (Raphanus sativus L.). In the present study, a comprehensive analysis of MADS-box genes was performed, and a total of 144 MADS-box family members were identified from the whole radish genome. Meanwhile, a detailed list of MADS-box genes from other 28 plant species was also investigated. Through the phylogenetic analysis between radish and Arabidopsis thaliana, all the RsMADS genes were classified into two groups including 68 type I (31 Mα, 12 Mβ and 25Mγ) and 76 type II (70 MIKCC and 6 MIKC∗). Among them, 41 (28.47%) RsMADS genes were located in nine linkage groups of radish from R1 to R9. Moreover, the homologous MADS-box gene pairs were identified among radish, A. thaliana, Chinese cabbage and rice. Additionally, the expression profiles of RsMADS genes were systematically investigated in different tissues and growth stages. Furthermore, quantitative real-time PCR analysis was employed to validate expression patterns of some crucial RsMADS genes. These results could provide a valuable resource to explore the potential functions of RsMADS genes in radish, and facilitate dissecting MADS-box gene-mediated molecular mechanisms underlying flowering and floral organogenesis in root vegetable crops.
The Effect of Spatial Interference Correlation and Jamming on Secrecy in Cellular Networks

Recent studies on secure wireless communication have shed light on a scenario where interference has a desirable impact on network performance. Particularly, assuming independent interference power fluctuations at the eavesdropper and the receiver, opportunistic secure information transfer can occur on the legitimate link. However, interference is spatially correlated due to the common set of interfering sources, which may diminish the opportunistic secure spectrum access (OSSA) probability. We study and quantify the effect of spatial interference correlation on OSSA in cellular-networks and investigate the potential of full-duplex jamming (FDJ) solutions. The results highlight the scenarios where FDJ improves OSSA performance.
Prime factor algorithm of discrete cosine transform

Prime factor fast algorithms are computationally efficient for various discrete transforms. However, they generally need an index mapping process to convert one-dimensional input sequence into a two-dimensional array, which results in a substantially computational overhead and an irregular computational structure. This letter attempts to minimize the computation overhead by a simple and general mapping procedure.
Seven Novel Methylation Guide Small Nucleolar RNAs Are Processed from a Common Polycistronic Transcript by Rat1p and RNase III in Yeast

ABSTRACT Through a computer search of the genome of the yeastSaccharomyces cerevisiae, the coding sequences of seven different box C/D antisense small nucleolar RNAs (snoRNAs) with the structural hallmarks of guides for rRNA ribose methylation have been detected clustered over a 1.4-kb tract in an inter-open reading frame region of chromosome XIII. The corresponding snoRNAs have been positively identified in yeast cells. Disruption of the nonessential snoRNA gene cluster specifically suppressed the seven cognate rRNA ribose methylations but did not result in any growth delay under the conditions of yeast culture tested. The seven snoRNAs are processed from a common polycistronic transcript synthesized from an independent promoter, similar to some plant snoRNAs but in marked contrast with their vertebrate functional homologues processed from pre-mRNA introns containing a single snoRNA. Processing of the polycistronic precursor requires nucleases also involved in rRNA processing, i.e., Rnt1p and Rat1p. After disruption of the RNT1 gene, the yeast ortholog of bacterial RNase III, production of the seven mature snoRNAs was abolished, while the polycistronic snoRNA precursor accumulated. In cells lacking functional Rat1p, an exonuclease involved in the processing of both pre-rRNA and intron-encoded snoRNAs, several processing intermediates of the polycistronic precursor accumulated. This allowed for the mapping in the precursor of the presumptive Rnt1p endonucleolytic cuts which provide entry sites for subsequent exonucleolytic trimming of the pre-snoRNAs. In line with known properties of double-stranded RNA-specific RNase III, pairs of Rnt1p cuts map next to each other on opposite strands of long double-helical stems in the secondary structure predicted for the polycistronic snoRNA precursor.
Surgical outcome of deep anterior lamellar keratoplasty with air-assisted manual dissection for corneas with previous inflammation or fibrosis

PURPOSE: To report our experience in air-assisted manual dissection deep anterior lamellar keratoplasty (DALK) for the treatment of corneal scar with previous inflammation and fibrosis. MATERIALS AND METHODS: We retrospectively reviewed the medical history of 21 patients (male:female = 13:8 mean age 41.9 years old) with corneal pathology from previous infection and inflammation. Trephination diameter ranged from 7.0 to 8.0 mm, and the graft was oversized by 0.25–0.50 mm. Debulking technique was performed to expose Descemet's membrane after filling stroma with air. Starting from postoperative 3 months, selective suture removal was performed to reduce corneal astigmatism. RESULTS: The mean follow-up period was 59.9 ± 19.8 (20–96) months. Intraoperative microperforation occurred in 2 eyes (9.5%); however, there was no shift to penetrating keratoplasty. Air-bubble tamponade was performed in 7 eyes (33.3%) for postoperative gapping of the graft. There were 2 failed grafts (9.5%) due to corneal ulcer while all the other grafts remained clear throughout follow-up. The mean preoperative best-corrected visual acuity (BCVA) was 1.84 ± 0.66 logMAR, which improved to 0.74 ± 0.63 (P < 0.01). The average sphere power was − 0.88 ± 3.88 diopter (D), average cylinder power 3.03 ± 1.46D, and average endothelial count 1877 ± 375 cells/mm2. CONCLUSION: In severe ocular surface diseases, big-bubble technique frequently failed to separate predescemtic plane; however, it effectively created air-filled stroma which was easier to remove. Although BCVA was suboptimal due to ocular surface disorders, graft survival and clarity rate is high, justifying the application of DALK in these cases.
Placental retention in late first and second trimester pregnancy termination using misoprostol: a retrospective analysis

Objective: Termination of pregnancy (TOP) for medical reasons is regularly performed using misoprostol. Presence of placental remnants followed by curettage, frequently complicate the procedure. Aim of this analysis is to audit our current policy for medical termination in late first and second trimester, looking at the management of third stage. Methods: A retrospective analysis of patient data was performed. Included were patients that underwent medical TOP in late first or second trimester. Patients were reviewed 6 weeks postdelivery. Characteristics of procedure, patient and pregnancy were analysed to determine factors associated with an increased risk of retained placenta/placental remnants. Results: We included 175 patients. Eighty-five patients (48%) underwent curettage immediately after delivery because of retained placenta or because placental remnants were suspected. Nineteen patients (11%) underwent curettage at later stage. All tissue was examined microscopically for confirmation of placental tissue. Analysis of characteristics of procedure, patients and pregnancies did not identify factors associated with an increased risk of retained placenta or placental remnants. Conclusion: A large number of immediate and late curettages was seen after medical TOP. Misoprostol-dose might play a role and the role of ultrasonographic assessment of the uterine cavity immediately post-placenta-delivery needs to be studied.
Demographic and clinical characteristics of traumatic shoulder dislocations in an urban city of Turkey: a retrospective analysis of 208 cases.

OBJECTIVE The aim of this study was to investigate the demographic and clinical characteristics of traumatic shoulder dislocations in an urban city of Turkey. METHODS The digital patient database was reviewed to identify all patients with glenohumeral dislocation of the shoulder admitted to the emergency departments of the two hospitals in Diyarbakır between January 2008 and December 2010. Incidence, demographics, clinical characteristics, recurrence, associated injuries, and mechanism of injury were evaluated. RESULTS Two hundred and eight patients (163 male, 45 female; mean age: 37.2±21.3) experienced traumatic shoulder dislocation during the study period. The overall incidence of primary shoulder dislocations was 5.3 per 100,000 person-years. Age distribution peaked between 21 and 30 years (96.5% male) and between 61 and 70 years (66.7% female). Primary shoulder dislocation occurred in 172 patients (82.7%) and recurrent dislocations in 36 (17.3%). Patients with recurrent shoulder dislocations were younger than those with primary dislocations (mean age, 29.7±14.5 and 38.8±22.2, respectively; p=0.020). There were 195 (93.4%) anterior dislocations. The mechanism of injury was falls in 155 (74.5%) cases. Reduction was achieved in 165 patients (79.3%) in the emergency department. General anesthesia was used for 43 patients (20.7%). CONCLUSION The 5.3 per 100,000 person-years incidence of traumatic shoulder dislocations in Turkey was much lower than previous studies. Demographic characteristics also showed various differences closely related to the population pyramid.
Institutional support and women’s entrepreneurial self-efficacy

Purpose The purpose of this study is to explores the extent to which local institutional forces affect female entrepreneurial venture performance. Drawing upon a unified theoretical framework of social cognitive and institutional perspectives, the authors scrutinize the complex interplay among institutional support, entrepreneurial cognitions and entrepreneurial success. Design/methodology/approach Based on a unique sample of 202 female entrepreneurs in 30 provinces throughout Japan, this paper grounded social cognitive theory and attempted to clear the relation between women’s entrepreneurial self-efficacy and venture performance empirically by statistical analysis. Findings The findings of structural equation modeling indicate that women’s entrepreneurial self-efficacy is a strong and useful mediator of the effect of informal institutional support on venture performance. Unexpectedly, formal institutional support shows no correlation with entrepreneurial self-efficacy. Practical implications This study proposes that perceived social legitimacy may lead to increased entrepreneurial self-efficacy, thereby enhancing venture performance. This finding can clarify the institutional force pathways to foster entrepreneurial confidence. Originality/value This study contributes to the field of female entrepreneurship by examining institutional antecedents of women’s entrepreneurial self-efficacy. Focused on the case of Japanese female entrepreneurs, this study is unique and valuable.
Origin and evolution of the Bainaimiao arc belt: Implications for crustal growth in the southern Central Asian orogenic belt

Recent results show that evolution of the huge Central Asian orogenic belt can be explained in terms of southwest Pacific–style accretion of arcs and microcontinents. A better understanding of the origin and evolution of arcs and microcontinents will enhance our knowledge on the evolution of the Central Asian orogenic belt. As one of the most important early Paleozoic arc systems south to the Solonker suture zone, the origin and evolution of the Bainaimiao arc belt are still not well constrained. New zircon U-Pb geochronological and geochemical results on magmatic rocks in the Bainaimiao arc belt indicate that the arc was active from 0.52 Ga to 0.42 Ga and can extend to east Siping in NE China. Zircon U-Pb geochronological results of metasedimentary rocks in the Bainaimiao arc belt indicate that they are early Paleozoic in age, not Precambrian as previously regarded. Detrital zircon analysis of metasedimentary rocks and Sr-Nd-Hf geochemical results of magmatic rocks indicate the existence of some Proterozoic basement rocks beneath the Bainaimiao arc, and it was built upon a Precambrian microcontinent that has a tectonic affinity to the Tarim or Yangtze cratons. The Bainaimiao arc is an ensialic island arc characterized by different evolution history and basement compositions from the northern North China craton. It was separated by a wide ocean from the northern North China craton during the Cambrian–Ordovician period. Successive northward subduction resulted in contraction of the ocean and final accretion of the Bainaimiao arc to the northern North China craton during the Late Silurian–earliest Devonian by arc-continent collision. Arc-continent collision could be an important mechanism for continental crustal growth and formation of the huge Central Asian orogenic belt.
Who Should Be Allowed to Sell Water in California? Third-Party Issues and the Water Market

Although significant water trading has occurred in California since the drought of the early 1990s, many localities have restricted water transfers because of the perceived harm to other users and the local economy. In Who Should Be Allowed to Sell Water in California? Third-Party Issues and the Water Market, Ellen Hanak examines water transfers in California, local resistance to them, and various approaches to resolving water disputes. Drawing on a new database of water transfers as well as interviews with state, county, and water district officials, the report calls for water management at the local level that balances the interests of other residents and the potential gains from transfers.
Epithelioid trophoblastic tumor of the uterus: A case report with radiologic–pathologic correlation

Herein, we report a rare case of an epithelioid trophoblastic tumor of the uterus with radiologic–pathologic correlation in a 56‐year‐old postmenopausal woman. On T2‐weighted magnetic resonance (MR) imaging, the tumor appeared as a hypointense irregular mass compared with the surrounding myometrium of the uterine corpus and encircled the cavity of the lower uterine segment. On dynamic contrast‐enhanced MR images, the tumor appeared as a hypovascular mass and an inhomogeneously hyperintense mass in the delayed phase. In addition, non‐contrast computed tomography images showed some spotty areas of very high density within the tumor. These radiologic findings were well correlated with the histological features, such as abundant hyalinization and calcification within the tumor. Accurate interpretation of MR and computed tomography findings was helpful to differentiate epithelioid trophoblastic tumor from other gestational trophoblastic diseases and uterine carcinomas.
Deep convection and upper‐tropospheric humidity: A look from the A‐Train

This work investigates the links between deep convective clouds and upper‐tropospheric humidity. We collocate data from AIRS, CloudSat, and the GDAS model output, and globally average and grid our results to seasonal scales for one year, 2007. The CloudSat cloud scenario retrieval is used as a reliable identifier of deep convective events, during which we extract the nearest 300‐mb humidity from AIRS and GDAS data. The zonal averages of thus screened data clearly show significant increase in the humidity, and suppression of the all‐sky outgoing long‐wave radiation.
Formation Process and Geography of Science–Industry Partnerships: The Case of the University of Poitiers

This paper tries to elicit new explanations into the geography of collaborations between science and industry by focusing on how they are initially set up. Two determining factors could influence this: constraints linked to the search for complementary resources and possibilities to connect with partners. An empirical study on collaborations established by several laboratories of the University of Poitiers with companies confirms this hypothesis. Searching for specific resources means fewer potential partners are available and explains the small number of local collaborations and the high number of partnerships with certain regions. However, these constraints alone do not suffice to determine the spatial scale of such collaborations. Analysing how connections are established particularly reveals that partners generally prefer to renew collaborations rather than initiate new ones. This leads to the existing geography of partnerships being reinforced.
Accuracy of Pedicle Screw Placement in Lumbar Vertebrae

Study Design. The location of pedicle screws (n = 42) in four human specimens of the lumbar spine and in 30 patients (n = 131 screws) after lumbar spinal fusion was assessed using computed tomography. Objectives. To determine the accuracy of pedicle screw placement in lumbar vertebrae and the reproducibility and repeatability of the computed tomography examination. Summary of Background Data. Failures in the placement of transpedicular screws for lumbar fusion are reported. The evaluation of such screws using computed tomography examination has not been investigated. Methods. After surgery, the specimens were dissected in transversal slices to observe macroscopically the location of the pedicle screw and to correlate these observations with the computed tomography images. All patients were examined by one observer. To determine the reproducibility and repeatability of the computed tomography examination, two observers studied computed tomography images of 12 patients (n = 58 screws) twice within 3 months. Results. In the specimens, 10 screws were observed to penetrate the medial wall of the pedicle. This correlated fully with the images. In the patients' group, 40% of all screws penetrated the cortex of the vertebra. Of all screws, 29% penetrated the medial wall of the pedicle. From the computed tomography images, it appeared that a deviation of more than 6 mm medially was a high risk for nerve root damage. Three months after his first examination, Observer 1 documented a different position in three of 58 screws (kappa = 0.90). Observer 2 found a different position in eight screws (kappa = 0.65). The comparison between the reviews of the two observers showed a different opinion for the first evaluation, four disagreements (2‐4 mm) and 17 disagreements (0‐2 mm; kappa = 0.34), and for the second evaluation, four disagreements (2‐4 mm) and 12 disagreements (0‐2 mm; kappa = 0.43). Conclusions. Correct placement of transpedicular screws for spinal fusion seems to be more difficult than it looks. The computed tomography scanning is useful for differential diagnosis of postoperative radicular syndromes after lumbar transpedicular fixation.
High‐yield secretion of recombinant gelatins by Pichia pastoris

Recombinant non‐hydroxylated gelatins based on mouse type I and rat type III collagen sequences were secreted from the methylotrophic yeast Pichia pastoris, using the Saccharomyces cerevisiae α‐mating factor prepro signal. Proteolytic degradation could be minimized to a large extent by performing fermentations at pH 3·0 and by adding casamino acids to the medium, even though gelatin is extremely susceptible to proteolysis due to its open, unfolded structure. Proteolytic cleavage at specific mono‐arginylic sites, by a putative Kex2‐like protease, could be successfully abolished by site‐directed mutagenesis of these sites. Production levels as high as 14·8 g/l clarified both were obtained, using multicopy tranformants. To our knowledge, this represents the highest level of heterologous protein secretion reported to date for P. pastoris. Copyright © 1999 John Wiley & Sons, Ltd.