Miracle-dz/UniFAR-FTUs huggingface dataset:
Noxious effect of cigarette smoking on periodontal health.

Periodontal probing depth, furcation involvement and tooth mobility were compared in smokers and non-smokers. The study covered 242 subjects aged 21–60 yr, 76 of whom were smokers. Oral hygiene status and dental care habits were above average and of similar standard in both groups (Pll = 0.9). Probing depth was measured at 6 sites around all teeth and sites with a depth of 4 mm or more were regarded as diseased. Both number and probing depth of pockets were significantly greater in smokers than in non-smokers. On average, smokers exhibited 36.0 sites with a probing depth of 4 mm or more, in contrast to 21.8 sites in non-smokers. Probing depth was 2.59 ± 0.06 (mean ± SEM) and 2.36 ± 0.03 in smokers and non-smokers, respectively. The relatively greater occurrence of pockets in smokers remained even when allowance was made for age and oral hygiene. There were also significantly increased numbers of teeth with furcation involvement, pocket involvement and hypermobility in smokers. It is concluded that smoking is associated with a deterioration in periodontal health and that the influence of smoking may be independent of plaque exposure.
Future Event Logic - Axioms and Complexity

In this paper we present a sound and complete axiomatization of future event logic. Future event logic is a logic that generalizes a number of dynamic epistemic logics, by using a new operator ⊲ that acts as a quantiﬁer over the set of all reﬁnements of a given model. (A reﬁnement is like a bisimulation except that from the three relational requirements only ‘atoms’ and ‘back’ need to be satisﬁed.) Thus the logic combines the simplicity of modal logic with some powers of monadic second order quantiﬁcation. We prove the axiomatization is sound and complete and discuss some extensions to the result.
DLMS: Ten Years of AI for Vehicle Assembly Process Planning

Since its presentation at the inaugural 1989 IAAI Conference (O'Brien et al. 1989), Ford's Direct Labor Management System (DLMS) has evolved from a prototype being tested at a single assembly plant to a fully-deployed application that is being utilized at Ford's assembly plants throughout the world. DLMS is Ford's automated solution to managing the automobile manufacturing process system at our vehicle assembly plants. This paper will describe our experiences and the lessons that have been learned in building and adapting an AI system to the rapidly-evolving world of automotive vehicle assembly process planning. We will cover issues such as knowledge base development and maintenance, knowledge representation, porting the system to different platforms and keeping the system viable and upto-date through various organizational and business practice changes. We will also discuss how DLMS has become an integral part of Ford's assembly process planning business.
FEYNMAN EFFECTIVE CLASSICAL POTENTIAL IN THE SCHRODINGER FORMULATION

New physical insight into the correspondence between path integral concepts and the Schr\"odinger formulation is gained by the analysis of the effective classical potential, that is defined within the Feynman path integral formulation of statistical mechanics. This potential is related to the quasi-static response of the equilibrium system to an external force. These findings allow for a comprehensive formulation of dynamical approximations based on this potential.
Fast and Space-Efficient Entity Linking for Queries

Entity linking deals with identifying entities from a knowledge base in a given piece of text and has become a fundamental building block for web search engines, enabling numerous downstream improvements from better document ranking to enhanced search results pages. A key problem in the context of web search queries is that this process needs to run under severe time constraints as it has to be performed before any actual retrieval takes place, typically within milliseconds. In this paper we propose a probabilistic model that leverages user-generated information on the web to link queries to entities in a knowledge base. There are three key ingredients that make the algorithm fast and space-efficient. First, the linking process ignores any dependencies between the different entity candidates, which allows for a O(k2) implementation in the number of query terms. Second, we leverage hashing and compression techniques to reduce the memory footprint. Finally, to equip the algorithm with contextual knowledge without sacrificing speed, we factor the distance between distributional semantics of the query words and entities into the model. We show that our solution significantly outperforms several state-of-the-art baselines by more than 14% while being able to process queries in sub-millisecond times---at least two orders of magnitude faster than existing systems.
The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway

Here we showed that hepatocellular carcinoma (HCC) cell lines with high metastatic potential had low levels of NDRG2. The iron chelator Dp44mT up-regulated NDRG2, suppressed epithelial-mesenchymal transition (EMT) and inhibited tumor metastasis in HCC having high metastatic potential. Also Dp44mT attenuated the TGF-β1-induced EMT in HCC having low metastatic potential. In agreement, silencing endogenous NDRG2 with shNDRG2 in HCC cells attenuated the effect of Dp44mT. We showed that the NDRG2/gp130/STAT3 pathway can mediate Dp44mT effects. In agreement, we found that a combination of NDRG2 expression and p-STAT3 levels is a strong predictor of prognosis in HCC patients. We suggest that up-regulation of NDRG2 by Dp44mT is a promising therapeutic approach in HCC.
Aalborg Universitet A Centralized Inter-Cell Rank Coordination Mechanism for 5 G Systems

Multiple transmit and receive antennas can be used to increase the number of independent streams between a transmitter-receiver pair, or to improve the interference resilience property with the help of linear minimum mean squared error (MMSE) receivers. An interference aware inter-cell rank coordination framework for the future fifth generation wireless system is proposed in this article. The proposal utilizes results from random matrix theory to estimate the mean signal-to-interference-plus-noise ratio at the MMSE receiver. In addition, a game-theoretic interference pricing measure is introduced as an inter-cell interference management mechanism to balance the spatial multiplexing vs. interference resilience trade-off. Exhaustive Monte Carlo simulations results demonstrating the performance of the proposed algorithm indicate a gain of around 40% over conventional non interference-aware schemes; and within around 6% of the optimum performance obtained using a brute-force exhaustive search algorithm.
Usage pattern of the complex masticatory muscles in the shingleback lizard, Trachydosaurus rugosus: A model for muscle placement.

This wide-ranging, omnivorous lizard of Australia has a very complex adductor muscle mass, with fibers differing in length by a factor of three and in insertion angle by 90 degrees. Stimulated muscles produce maximal moment with the mouth nearly fully open. The opening mechanism appears to involve only simple rotation and no translation of the mandible. EMGs indicate that the entire mass is activated equivalently in crushing and there are no temporal subdivisions, for instance, matching activity to angle of opening. During crushing of hard objects, the chin is brought into contact with the ground so that the subvertebral muscles may aid buccal closure. The lizards also activate the muscles in a pulsatile staircase effect leading to an unfused tetanus that generates forces several times the twitch level. Application in parallel of a maximum number of sarcomeres to the crushing bite appears to be the major design characteristic. Hence, this species offers an ideal case for analysis of the effects of different sarcomere placements on the simple movement generated. For the primary adductor muscles, the angles of fiber insertion relative to the lines connecting each insertion with the jaw joint are equivalent; this relation persists as the mouth opens. Also, fiber lenghts are proportional to the distance between jaw joint and site of insertion so that each sarcomere contributes equally to the movement generated. Complex tendons provide additional space for muscle placement. Some of these also extend beyond the bony attachment sites, producing tendinous "coronoid processes. " The fibers of laterally and ventrally placed muscles are short relative to the length of the entire muscle, insert at relatively short moment arms, and undergo short excursion during opening; however, there are many such fibers. Also, muscles with a low incident angle are crossed; they apparently protect the jaw joint from horizontal (disarticulating) forces.
The Relationship Between Racial and Ethnic Identity in Black Adolescents: The Cross Racial Identity Scale and the Multigroup Ethnic Identity Measure

Ethnic identity and racial identity are related terms that are often used interchangeably, although the theoretical models differ. In this study, we examined the relationship between ethnic identity attitudes operationalized by Multigroup Ethnic Identity Measure (MEIM; Phinney, 1992) scores and racial identity attitudes operationalized by Cross Racial Identity Scale (CRIS; Vandiver et al., 2000) scores in a sample of 143 adolescents. Bivariate analyses indicated that scores on the MEIM's Ethnic Identity subscale had modest positive correlations with Afrocentricity scores of the CRIS and negative correlations with Assimilation and Self-Hatred scores. Other Group Orientation scores from the MEIM were positively related to Multicultural scores on the CRIS and negatively related to Anti-White scores. A canonical correlation yielded 2 interpretable functions labeled Black Racial/Ethnic Identification and Grounded Multiculturalism. Black Racial/Ethnic Identification was characterized by high proethnic and pro-racial scores and low scores on non-ethnic/racial subscales, and Grounded Multiculturalism was characterized by high pro-ethnic scores as well as high pro-other scores.
The Reading of Ludwik Fleck: Questions of Sources and Impetus

The rediscovery in the mid‐1970s of Ludwik Fleck’s initially neglected monograph, Entstehung und Entwicklung einer Wissenschaftlichen Tatsache, published in 1935 and translated in 1979 as Genesis and Development of a Scientific Fact, has resulted in extensive, still ongoing, secondary writings, mainly within the humanities. Fleck has been interpreted as furthering a relativistic conception of science. Nowadays, he is often viewed as an important contributor to contemporary sociology of science and a forerunner to Thomas Kuhn. Fleck’s account of the Wassermann reaction, which forms the basis of his epistemology, has been praised as developed by a scientist well acquainted with the field in question. Because of the scarcity of available material on Fleck, however, the question of his sources has remained an unsolved issue. In the present article, an alternative reading is suggested. By focusing on the scientific content of the monograph, mainly neglected in the modern interpretations of Fleck, and on the so far overlooked sources of his writings traced back to their German origin, a better understanding of Fleck’s account of the Wassermann reaction can be given. The consequences of this alternative reading for the conception of Fleck’s monograph and for the impetus of his mission are discussed.
Victim age, attractiveness and, abuse history as factors in the perception of a hypothetical child sexual abuse case

Abstract This study examines the effect of victim age, victim attractiveness, the victim's abuse history and respondent gender have on attributions of blame and credibility towards a female victim in a hypothetical child sexual abuse case. A total of 397 respondents from a community sample read a hypothetical child sexual abuse (CSA) scenario in which victim age, victim attractiveness and the victim's abuse history were manipulated. Respondents then completed a 16-item blame attribution questionnaire. Several predictions were made. First, a 10-year-old victim would be deemed less blameworthy and more credible than a 15-year-old victim. Secondly, an attractive victim would be viewed more positively, and attributed less blame, than an unattractive victim. Thirdly, a victim with previous history of being sexual abused—either by the same or different perpetrators—would be deemed more culpable for their own CSA than a first time victims. Finally, female respondents were expected to take a more pro-victim and anti-perpetrator stance than males. Whilst comparatively few differences were found across victim attractiveness and abuse history. Overall findings were broadly in line with predictions. It was concluded that victim age and respondent gender play particularly important roles in the attribution of blame towards victims and perpetrators of child sexual abuse.
Weapons of Mass Distraction: Optimal Innovation and Pleasure Ratings

In 6 experiments we test the Optimal Innovation Hypothesis, according to which an optimally innovative stimulus, such that induces a novel response while allowing for the recovery of a salient one (Giora, 1997b, 2003), would be rated as more pleasing than either a more or a less familiar stimulus. Experiment 1 shows that it is the stimulus that meets the requirements for optimal innovativeness that is most pleasurable. Reading times obtained in Experiment 2 support the assumption that the stimuli found most pleasurable involve processing a salient meaning. Experiment 3 corroborates the results of Experiment 1 and Experiment 2, showing that they also hold for identical (rather than different) stimuli. Experiment 4 controls for the possibility that the lengthy reading times found earlier might reflect lack of understanding. Experiment 5 shows that optimal innovation supersedes figurativity. Experiment 6 demonstrates that the Optimal Innovation Hypothesis applies to nonverbal stimuli as well.
Precision in Career Motivation Assessment

The Subjective Science Attitude Change Measures (SSACM; Stake & Mares, 2001) represent a collection of useful self-report tools for assessing change in high school students’ science attitudes as a function of a given motivational intervention. Despite the survey’s utility, little work has been done to examine this tool among other samples (i.e., college students) or to test the psychometric properties and overall construct validity of SSACM scores. Participants (N = 1,368) consisted of undergraduate students enrolled in biology, chemistry, and physics laboratory classes. Analysis of the SSACM’s factor structure using exploratory structural equation modeling indicated support for a bifactor structure consisting of one general science motivation factor and three specific factors labeled intrinsic science interest, science career identity, and science self-efficacy. This model outperformed alternative bifactor and specific two- and three-factor models. Results largely yielded evidence of concurrent validity, as three of the four scale scores were significant positive predictors of relevant outcomes over and above the contribution of gender, parental occupation type, and mastery motivation. Implications for science career counseling and assessment are discussed.
Record-setting algal bloom in Lake Erie caused by agricultural and meteorological trends consistent with expected future conditions

In 2011, Lake Erie experienced the largest harmful algal bloom in its recorded history, with a peak intensity over three times greater than any previously observed bloom. Here we show that long-term trends in agricultural practices are consistent with increasing phosphorus loading to the western basin of the lake, and that these trends, coupled with meteorological conditions in spring 2011, produced record-breaking nutrient loads. An extended period of weak lake circulation then led to abnormally long residence times that incubated the bloom, and warm and quiescent conditions after bloom onset allowed algae to remain near the top of the water column and prevented flushing of nutrients from the system. We further find that all of these factors are consistent with expected future conditions. If a scientifically guided management plan to mitigate these impacts is not implemented, we can therefore expect this bloom to be a harbinger of future blooms in Lake Erie.
Stochastic Quasi-Newton Langevin Monte Carlo

Recently, Stochastic Gradient Markov Chain Monte Carlo (SG-MCMC) methods have been proposed for scaling up Monte Carlo computations to large data problems. Whilst these approaches have proven useful in many applications, vanilla SG-MCMC might suffer from poor mixing rates when random variables exhibit strong couplings under the target densities or big scale differences. In this study, we propose a novel SG-MCMC method that takes the local geometry into account by using ideas from Quasi-Newton optimization methods. These second order methods directly approximate the inverse Hessian by using a limited history of samples and their gradients. Our method uses dense approximations of the inverse Hessian while keeping the time and memory complexities linear with the dimension of the problem. We provide a formal theoretical analysis where we show that the proposed method is asymptotically unbiased and consistent with the posterior expectations. We illustrate the effectiveness of the approach on both synthetic and real datasets. Our experiments on two challenging applications show that our method achieves fast convergence rates similar to Riemannian approaches while at the same time having low computational requirements similar to diagonal preconditioning approaches.
The use of referring expressions in narratives by Mandarin heritage language children and the role of language environment factors in predicting individual differences*

This study investigated the referring expressions used for first mentions of participants and entities in narratives by Mandarin heritage language (HL) and monolingual children. Referring expressions for first mentions in Mandarin comprise lexical, morphological and syntactic devices. Results showed that HL children used less adequate referring expressions for first mentions than the monolinguals, mainly due to overgeneralization of classifiers and lack of vocabulary knowledge. However, HL children did not differ from monolinguals in their use of relative clauses and post-verbal NP placement to mark first mentions. These results suggest that incomplete acquisition of the HL may vary across different linguistic subdomains (Montrul, 2008); specifically, domains requiring a great deal of input to acquire, such as vocabulary and the large repertoire of classifier morphemes, might be more vulnerable in HL speakers than syntax. Mixed modeling analyses revealed that older age of arrival, higher maternal education levels and a rich and diverse Mandarin environment at home predicted stronger narrative outcomes, also pointing to an important role for input in HL acquisition.
The MIMO Wireless Switch: Relaying can increase the multiplexing gain

This paper considers an interference network composed of K half-duplex single-antenna pairs of users who wish to establish bi-directional communication with the aid of a multi-input-multi-output (MIMO) half-duplex relay node. This channel is referred to as the “MIMO Wireless Switch” since, for the sake of simplicity, our model assumes no direct link between the two end nodes of each pair implying that all communication must go through the relay node (i.e., the MIMO switch). Assuming a delay-limited scenario, the fundamental limits in the high signal-to-noise ratio (SNR) regime is analyzed using the diversity-multiplexing tradeoff (DMT) framework. Our results sheds light on the structure of optimal transmission schemes and the gain offered by the relay node in two distinct cases, namely reciprocal and non-reciprocal channels (between the relay and end-users). In particular, the existence of a relay node, equipped with a sufficient number of antennas, is shown to increase the multiplexing gain; as compared with the traditional fully connected K-pair interference channel. To the best of our knowledge, this is the first known example where adding a relay node results in enlarging the pre-log factor of the sum rate. Moreover, for the case of reciprocal channels, it is shown that, when the relay has a number of antennas at least equal to the sum of antennas of all the users, static time allocation of decode and forward (DF) type schemes is optimal. On the other hand, in the non-reciprocal scenario, we establish the optimality of dynamic decode and forward in certain relevant scenarios.
Minimax robust active learning for approximately specified regression models

We address problems of model misspecification in active learning. We suppose that an investigator will sample training input points (predictors) from a subpopulation with a chosen distribution, possibly different from that generating the underlying whole population. This is in particular justified when full knowledge of the predictors is easily acquired, but determining the responses is expensive. Having sampled the responses the investigator will estimate a, possibly incorrectly specified, regression function and then predict the responses at all remaining values of the predictors. We derive functions r(x) of the predictors x , and carry out probability weighted sampling with weights proportional to r(x) . The functions r(·) are asymptotically minimax robust against the losses incurred by random measurement error in the responses, sampling variation in the inputs, and biases resulting from the model misspecification. In our applications the values of r(·) are functions of the diagonal elements of the “hat” matrix which features in a regression on the entire population; this yields an interpretation of sampling the “most influential” part of the population. Applications on simulated and benchmark data sets demonstrate the strong gains to be achieved in this manner, relative to passive learning and to previously proposed methods of active learning. We go on to illustrate the methods in the context of a case study relating ice thickness and snow depth at various locations in Canada, using a “population” of about 50,000 observations made available by Statistics Canada. The Canadian Journal of Statistics 46: 104–122; 2018 © 2017 Statistical Society of Canada
Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils1

Posttranslational modifications, such as the deimination of arginine to citrulline by peptidyl arginine deiminase (PAD4), change protein structure and function. For autoantigens, covalent modifications represent a mechanism to sidestep tolerance and stimulate autoimmunity. To examine conditions leading to histone deimination in neutrophils, we used Abs that detect citrullines in the N terminus of histone H3. Deimination was investigated in human neutrophils and HL-60 cells differentiated into granulocytes. We observed rapid and robust H3 deimination in HL-60 cells exposed to LPS, TNF, lipoteichoic acid, f-MLP, or hydrogen peroxide, which are stimuli that activate neutrophils. Importantly, we also observed H3 deimination in human neutrophils exposed to these stimuli. Citrullinated histones were identified as components of extracellular chromatin traps (NETs) produced by degranulating neutrophils. In contrast, apoptosis proceeded without detectable H3 deimination in HL-60 cells exposed to staurosporine or camptothecin. We conclude that histone deimination in neutrophils is induced in response to inflammatory stimuli and not by treatments that induce apoptosis. Our results further suggest that deiminated histone H3, a covalently modified form of a prominent nuclear autoantigen, is released to the extracellular space as part of the neutrophil response to infections. The possible association of a modified autoantigen with microbial components could, in predisposed individuals, increase the risk of autoimmunity.