Miracle-dz/UniFAR-FTUs huggingface dataset:
An Improved Algorithm for Sensor Monitoring in WSANs

This paper presents an improved algorithm for sensor monitoring based on the algorithm proposed by Dilman et al. in [3]. By analyzing the probability of the alarm occurrence with the updated information, the proposed algorithm prolongs the interval between two consecutive polling periods when no alarm could occur. This method reduces the amount of monitoring traffic further than the method in [3] and still guarantees the detection of the alarm. The simulation results show that the proposed monitoring scheme reduces both the number of polling and the cost of the management of WSANs, consequently improves the performance.
The role of positron-emission tomography in the diagnosis of giant cell arteritis : A systematic review and meta-analysis

Background: Giant cell arteritis (GCA) is an inflammatory disease of the larger vessels, typically affecting the temporal arteries, but involvement of the carotid and thoracic arteries is not uncommon. Serious complications such as blindness can occur if the disease is left untreated. Currently, the gold standard test for GCA is a temporal biopsy, but this invasive technique is not without risks and frequently inaccurate. We investigate the use of 18-fluoro-desoxyglucose (18F-FDG) positron emission tomography (PET) as a new diagnostic means in GCA. Methods: We performed a literature search in the MEDLINE database for original research articles written in the English language that discussed the use of PET in diagnosing GCA. After applying selection criteria, 9 articles were included for literature review and 4 of these were incorporated in a meta-analysis. Results: 18-FDG uptake in the extracranial arteries is correlated to the presence GCA within patients suspected for vasculitis. In our meta-analysis we found the following results: sensitivity 85% (95% CI; 74-92%, I2=0.0%), specificity 91% (95% CI; 82-96%, I2=31.2%), positive likelihood ratio 7.18 (95% CI; 3.43-15.06, I2 =10.1%) and negative likelihood ratio 0.19 (95% CI; 0.11-0.33, I2= 0.0%). Discussion: 18F-FDG-PET cannot replace temporal artery biopsy at the present time, because of its limited ability to visualise the cranial arteries. However, PET may be provide valuable information when extracranial involvement is suspected, specifically in biopsy-negative patients who are strongly suspected of having GCA.
Financial Regulation and Securitization: Evidence from Subprime Mortgage Loans

We examine the consequences of existing regulations on the quality of mortgage loans originations in the originate-to-distribute (OTD) market. The information asymmetries in the OTD market can lead to moral hazard problems on the part of lenders. We find, using a plausibly exogenous source of variation in the ease of securitization, that the quality of loan origination varies inversely with the amount of regulation: more regulated lenders originate loans of worse quality. We interpret this result as a possible evidence that the fragility of lightly regulated originators’ capital structure can mitigate moral hazard. In addition, we find that incentives which require mortgage brokers to have ‘skin in the game’ and stronger risk management departments inside the bank partially alleviate the moral hazard problem in this setting. Finally, having more lenders inside a mortgage pool is associated with higher quality loans, suggesting that sharper relative performance evaluation made possible by more competition among contributing lenders can also mitigate the moral hazard problem to some extent. Overall, our evidence suggests that market forces rather than regulation may have been more effective in mitigating moral hazard in the OTD market. The findings caution against policies that impose stricter lender regulations which fail to align lenders’ incentives with the investors of mortgage-backed securities. & 2009 Elsevier B.V. All rights reserved.
Dynamic balance and gait speed improve in persons with Parkinson´s disease after Lee Silverman Voice Treatment (LSVT)-BIG training: a single subject experimental design study

Abstract Background: Parkinson ́s disease (PD) is characterised by small, slow movements affecting balance and gait. Lee-Silverman-Voice-Treatment-(LSVT)-BIG is an intensive intervention aiming to restore normal amplitudes of movements. This study aimed to examine whether LSVT-BIG influences dynamic balance and gait in persons with PD. Methods: We used a Single-Subject-Experimental-Design with three phases; phase A (2 weeks) with no treatment, phase B (4 weeks) with LSVT-BIG-treatment and LSVT-BIG-home-training, and phase C (7–8 weeks) with LSVT-BIG-home-training. Two persons with PD participated. Outcome measures included the Mini-Balance-Evaluation-Systems-Test (Mini-BESTest) with its four subcomponents (‘anticipatory postural adjustments’, ‘postural responses’, ‘sensory orientation’, ‘balance during gait’), the Step-Test (ST) and 10-Meter-Walk-Test-fast (10MWT-fast). The participants were assessed 6, 4 and 8 times during phase A, B and C, respectively. During phase B, they received 16 individual 1-hour LSVT-BIG-treatment sessions and completed between 28 and 39 1-hour sessions LSVT-BIG-home-training. During phase C, they were encouraged to complete one session of home-training every day. Results: The Mini-BESTest-total-score, ‘balance during gait’, ST and 10MWT-fast improved significantly in both participants. One participant demonstrated improved ‘postural responses’. Two of the Mini-BESTest subcomponents were not sensitive to possible improvements. Conclusion: LSVT-BIG may have a positive effect on dynamic balance and gait-speed in persons with PD.
Stock Market Assessment of Bank Risk: Evidence from the Maghreb Region

Abstract This paper examines the ability of stock market investors to monitor bank risk for a sample of listed banks in Tunisia and Morocco over the period 2003-2009. We construct numerous market-based risk measures: market beta, idiosyncratic risk component and total volatility of bank stock returns derived from the market model as well as the distance-to-default derived from the structural model of credit risk. Using a panel data analysis, we show that market-based measures of risk are strongly associated to bank fundamental characteristics. This finding has important implications for regulators as shareholders are able to assess bank financial condition and hence exert effective discipline on bank risk-taking behavior.
Perceived responsibility for developing and maintaining home-school partnerships: the experiences of parents and practitioners

Encouraging partnerships between parents of children with special educational needs and disabilities (SEND) and educational practitioners is a key theme in educational policy in England. However, there are unanswered questions regarding whether parents and teachers are mutually responsible for developing and maintaining these partnerships, as well as a paucity of literature eliciting the views of educational practitioners from a SEND context. This article draws on a study which explored parent and teacher experiences of partnership, specifically focusing on perceptions of responsibility regarding the development and maintenance of these partnerships. In‐depth interviews were conducted with 22 parents of children with a wide range of SENDs, and 15 educational practitioners. Findings highlighted that although there appeared to be perceived mutual responsibility regarding home–school communication, educational practitioners were overall held accountable for developing and maintaining partnerships, and were required to be trustworthy and approachable in order for positive home–school relationships to flourish. [ABSTRACT FROM AUTHOR]
Atlantic salmon (Salmo salar) require increased dietary levels of B-vitamins when fed diets with high inclusion of plant based ingredients

Aiming to re-evaluate current recommendations for nutrient supplementations when Atlantic salmon are fed diets based on plant ingredients, two regression experiments, with parr and post-smolt, were conducted. A control diet was included to evaluate if ingredients supplied sufficient nutrients without any added nutrient package (NP). The nutrient package consisted of vitamins B, C, E, minerals, cholesterol, methionine, taurine and histidine. This paper focus on B-vitamins. In parr, growth, health and welfare parameters responded on NP additions, but this was not observed in the seawater stage. During three months of feeding, parr tripled their weight. Parr given diets added the NP above NRC (2011) showed improved protein retention, and reduced liver and viscera indices. Post-smolt fed the same diets during five months showed a doubling of weight, but did not respond to the variation in NP to the same extent as parr. Significant regressions were obtained in body compartments for several of the B-vitamins in the premix. Whole body biotin concentration was unaffected by micronutrient premix level, and mRNA expression of the enzymes dependent of biotin showed only weak increases with increased biotin. Muscle thiamine plateaued at a diet level similar to NRC (2011) recommendation in freshwater, and showed stable values independent on premix addition in seawater. The mRNA expression of the enzyme G6PDH (glucose-6-phosphate dehydrogenase) is sensitive to thiamine availability; results did not indicate any need to add thiamine above levels recommended for fish in general. Niacin showed a steady increase in whole body concentrations as feed niacin increased. Muscle riboflavin peaked at a diet level of 12.4 mg kg−1. Sufficient riboflavin is important to avoid e.g., development of cataract. Cataract was not registered to be any problem, neither in fresh- nor in seawater. Cobalamin (B 12) in muscle and liver was saturated at 0.17 mg kg−1 diet. Muscle pyridoxine showed a dose-dependent level in muscle, and peaked around 10 mg kg −1 diet. White muscle ASAT (asparagine amino transferase) activity steadily increased, with indications of stable values when dietary pyridoxine was around 10–16 mg kg −1 diet. Pantothenic acid increased in gill tissue up to a level of 5.5 mg kg −1 soft gill tissue; at a dietary level of 22 mg kg−1. Improved performance, and coverage of metabolic need for niacin was at a dietary level of 66 mg kg −1, riboflavin 10–12 mg kg−1, pyridoxine 10 mg kg−1 and panthotenic acid 22 mg kg−1. Based on these results, recommended B-vitamin supplementation in plant based diets for Atlantic salmon should be adjusted.
Functional status after intensive care: a challenge for rehabilitation professionals to improve outcome.

OBJECTIVE To examine restrictions in daily functioning from a rehabilitation perspective in patients one year after discharge from the intensive care unit, and to identify prognostic factors for functional status. DESIGN Cross-sectional design. PATIENTS Consecutive patients who were admitted to the intensive care unit for more than 48 h (n = 255). METHODS One year after intensive care, functional status (Sickness Impact Profile) as primary outcome, and Quality of Life (SF-36), anxiety and depression (Hospital Anxiety Depression Scale), and post-traumatic stress disorder (Impact of Events Scale) were evaluated. RESULTS Fifty-four percent of the patients had restrictions in daily functioning. Walking and social activities were most frequently restricted (30-60% of the patients). Quality of life was lower than the general Dutch population. Symptoms of anxiety and depression were found in 14%, and post-traumatic stress disorder in 18%. Severity of illness at admission and length of stay in the intensive care unit were identified as prognostic factors, although they explained only 10% of functional status. CONCLUSION The high prevalence of long-lasting restrictions in physical, social and psychological functioning among patients who stayed in the intensive care unit for at least 2 days implies that these patients are a potential target population for rehabilitation medicine. Multidisciplinary therapies need to be developed and evaluated in order to improve outcome.
Mapping Human Pitch Representation in a Distributed System Using Depth-Electrode Recordings and Modeling

Depth-electrode recordings from the auditory cortex of humans undergoing presurgical evaluation for epilepsy allow the recording of ensemble responses to pitch in the form of local field potentials. These recordings allow another test of the hypothesis that there is a specialized neural ensemble for pitch within auditory cortex. Moreover, the technique allows recordings from multiple sites with millisecond temporal resolution to allow modeling of the effective connectivity between these sites. Here we argue that this takes the form of a hierarchical network of pitch-sensitive regions. Activity can be understood as reflecting predictive coding, in which perceptual predictions and error messages are continuously exchanged between a higher pitch center and lower-level auditory cortex.
The flexible semantic integration of gestures and words: Comparing face-to-face and telephone dialogues

One measure of the communicative function of gestures is to test how speakers’ gestures are influenced by whether an addressee can see them or not, that is, by manipulating visibility between participants. We question traditional dependent variables (i.e., rate measures), suggesting that they may have been insufficient for capturing essential differences in the gestures speakers use in each condition. We propose that investigating the qualitative features of gestures is a more nuanced, and ultimately more informative approach. We examined how speakers distributed information between their gestures and words, testing whether this distribution was affected by the visibility of their addressee. Twenty pairs of undergraduates took part in conversations that were either face to face (n = 10) or on the telephone (n = 10). Each speaker described a drawing of an elaborate dress to the addressee. We used a semantic feature analysis to analyze descriptions of the dress’ skirt and assessed when words or gestures contributed information about five categories pertaining to features of the skirt’s unusual shape. Although speakers’ rates of gesturing and number of words did not vary significantly between conditions, speakers contributed more information and conveyed more categories in their gestures when the addressee would see them, while words carried the informational burden when addressees would not see the gestures (p’s < .001). These results suggest that gestures serve a communicative function. The semantic feature analysis is thus an example of how to explore gestures’ qualitative features within a quantitative paradigm.
The Cost of Treating Advanced Non-Small Cell Lung Cancer: Estimates from the Chinese Experience

Background Because of the potentially significant economic burden of healthcare costs associated with many diseases, it is critical that regulatory and medical insurance organisations collect and utilise data on the cost-effectiveness of care provision to make rational policy decisions. However, little is known about healthcare costs in China. Methodology/Principal Findings Based on health expenditure data for 253 cases of advanced non-small cell lung cancer (NSCLC) registered at the Second Xiangya Hospital of Central South University in China between 2006 and 2010, the cost of care provision was analysed. The monthly and aggregate annual medical costs were estimated for patients who were in either a progression-free state (PFS) or a disease-progression state (DPS). Monthly healthcare costs accumulated during the terminal 3 months were collected separately. The mean cost of treatment for PFS and DPS patients over one year was approximately US$11,566 and $14,519, respectively. The monthly costs for all patients were higher initially than in the subsequent months (PFS: $2,490; DPS: $2,503). For PFS patients, healthcare expenditures stabilised after the 7th month, with a mean monthly medical expenditure of $82.49. For DPS patients, expenditures stabilised after the 9th month, and the mean expenditure during the 9th month was $307.9. Medical care costs in the three successive months prior to death were $3,754, $5,829 and $7,372, respectively. Conclusions/Significance The economic evaluation of health care technologies is becoming ever more important in China, especially in disease areas for which new and expensive therapies are being introduced on a regular basis. This is first paper to present empirically estimated China-specific costs associated with the treatment of NSCLC. The cost estimates are presented in a format that is specifically intended to inform cost-effectiveness analyses of treatments for NSCLC, and hence, contribute to the more efficient allocation of limited healthcare resources in China.
Size-sorting dust grains in the surface layers of protoplanetary disks

Context. The shape of dust emission features measured from protoplanetary disks contains information about the typical size of the dust particles residing in these disks. A flattened 10 μm silicate feature is often interpreted as proof that grain growth has taken place, while a pointy feature is taken as evidence for the pristine nature of the dust. Aims. We wish to investigate what the effect of dust sedimentation is on the observed 10 μm feature and how this may affect the interpretation of the observations. Methods. Using a combination of modeling tools, we simulated the sedimentation of a dust grain size distribution in an axisymmetric 2-D model of a turbulent protoplanetary disk, and we used a radiative transfer program to compute the resulting spectra. Results. We find that the sedimentation can turn a flat feature into a pointy one, but only to a limited degree and for a very limited set of particle size distributions. If the distribution is too strongly dominated by small grains, then the feature is pointy even before sedimentation. If the distribution is too strongly dominated by big grains, the sedimentation will not be enough to cause the feature to be pointy. Only if we have a bimodal size distribution, i.e. a very small grain population and a bigger grain population, do we find that the transformation from a flat to a pointy feature upon dust sedimentation is strong. However, our model shows that, if sedimentation is the sole reason for the variety of silicate feature strengths observed in protoplanetary disks, then we would expect to find a correlation such that disks with weak mid- to far-infrared excess have a stronger 10 μm silicate feature than disks with a strong mid- to far-infrared excess. If this is contrary to what is observed, then this would indicate that sedimentation cannot be the main reason for the variety of 10 μm silicate features observed in protoplanetary disks.
The contribution of NMDA and non-NMDA receptors to fast and slow transmission of sensory information in the rat SI barrel cortex

The main objective of this study was to establish the contribution of NMDA receptors to natural processing of somatosensory information within rat SI barrel cortex. Responses of 52 cells in layers I-IV of the rat barrel cortex were analyzed by PSTH (peristimulus histogram) analysis of evoked spikes in reply to brief deflections of the principal whisker in animals anesthetized with urethane. Short and longer peak latency responses within PSTHs were compared in the presence and absence of the specific NMDA and non-NMDA antagonists D(-)- 2-amino-5-phosphonovaleric acid and 6,7-dinitroquinoxaline-2,3-dione, which were administered locally to neurons by iontophoresis and additionally tested against their putative specific agonists, NMDA and quisqualate, respectively. The results suggest the following. (1) The generation of most spikes from cells in layers I-IV is dependent upon activation of NMDA receptors. However, NMDA receptors do not contribute to responses at very short latencies commensurate with monosynaptic thalamocortical relay for layer IV cells. These appear to be entirely mediated through non-NMDA receptors. (2) In the absence of transmission through NMDA receptors, non-NMDA receptors do not generate significant spike activity in later (10–100 msec latency) discharges. (3) NMDA receptor participation in first spike generation is directly dependent upon the latency of response of the cell to principal whisker deflection. (4) Latency of response, non-NMDA receptor-mediated spike generation and laminar location were powerfully covariant. (5) In addition, it was found that cells exhibiting short-duration spikes ( < 0.7 msec; “fast-spike units”) in layer IV responded powerfully at short latencies, first spikes being entirely dependent upon non-NMDA but not NMDA receptor action, later spikes (10–100 msec poststimulus) being > 80% dependent upon NMDA receptor action. It is concluded that most sensorially driven spike activity in layers I-IV is dependent upon NMDA receptor action. This appears to be enabled by contingent subthreshold depolarization largely through non-NMDA receptor action, whereas the earliest thalamocortical discharges are evoked solely through non-NMDA receptors.
Phylogenetic comparison and classification of laccase and related multicopper oxidase protein sequences

A phylogenetic analysis of more than 350 multicopper oxidases (MCOs) from fungi, insects, plants, and bacteria provided the basis for a refined classification of this enzyme family into laccases sensu stricto (basidiomycetous and ascomycetous), insect laccases, fungal pigment MCOs, fungal ferroxidases, ascorbate oxidases, plant laccase‐like MCOs, and bilirubin oxidases. Within the largest group of enzymes, formed by the 125 basidiomycetous laccases, the gene phylogeny does not strictly follow the species phylogeny. The enzymes seem to group at least partially according to the lifestyle of the corresponding species. Analyses of the completely sequenced fungal genomes showed that the composition of MCOs in the different species can be very variable. Some species seem to encode only ferroxidases, whereas others have proteins which are distributed over up to four different functional clusters in the phylogenetic tree.
Labor Movement: How Migration Regulates Labor Markets

Throughout the industrialized world, international migrants serve as nannies, construction workers, gardeners and small-business entrepreneurs. Labor Movement suggests that the international migration of workers is necessary for the survival of industrialized economies. The book thus turns the conventional view of international migration on its head: it investigates how migration regulates labor markets, rather than labor markets shaping migration flows. Assuming a critical view of orthodox economic theory, the book illustrates how different legal, social and cultural strategies towards international migrants are deployed and coordinated within the wider neo-liberal project to render migrants and immigrants vulnerable, pushing them into performing distinct economic roles and into subordinate labor market situations. Drawing on social theories associated with Pierre Bourdieu and other prominent thinkers, Labor Movement suggests that migration regulates labor markets through processes of social distinction, cultural judgement and the strategic deployment of citizenship. European and North American case studies illustrate how the labor of international migrants is systematically devalued and how popular discourse legitimates the demotion of migrants to subordinate labor. Engaging with various immigrant groups in different cities, including South Asian immigrants in Vancouver, foreigners and Spataussiedler in Berlin, and Mexican and Caribbean offshore workers in rural Ontario, the studies seek to unravel the complex web of regulatory labor market processes related to international migration. Recognizing and understanding these processes, Bauder argues, is an important step towards building effective activist strategies and for envisioning new roles for migrating workers and people. The book is a valuable resource to researchers and students in economics, ethnic and migration studies, geography, sociology, political science, and to frontline activists in Europe, North America and beyond.