Miracle-dz/UniFAR-FTUs huggingface dataset:
THE URINE PROTEOME FOR RADIATION BIODOSIMETRY: EFFECT OF TOTAL BODY VS. LOCAL KIDNEY IRRADIATION

Victims of nuclear accidents or radiological terrorism are likely to receive varying doses of ionizing radiation inhomogeneously distributed over the body. Early biomarkers may be useful in determining organ-specific doses due to total body irradiation (TBI) or partial body irradiation. The authors used liquid chromatography and mass spectrometry to compare the effect of TBI and local kidney irradiation (LKI) on the rat urine proteome using a single 10-Gy dose of x-rays. Both TBI and LKI altered the urinary protein profile within 24 h with noticeable differences in gene ontology categories. Some proteins, including fetuin-B, tissue kallikrein, beta-glucuronidase, vitamin D-dependent calcium binding protein and chondroitin sulfate proteoglycan NG2, were detected only in the TBI group. Some other proteins, including major urinary protein-1, RNA binding protein 19, neuron navigator, Dapper homolog 3, WD repeat and FYVE domain containing protein 3, sorting nexin-8, ankycorbin and aquaporin were detected only in the LKI group. Protease inhibitors and kidney proteins were more abundant (fraction of total scans) in the LKI group. Urine protein (Up) and creatinine (Uc) (Up/Uc) ratios and urinary albumin abundance decreased in both TBI and LKI groups. Several markers of acute kidney injury were not detectable in either irradiated group. Present data indicate that abundance and number of proteins may follow opposite trends. These novel findings demonstrate intriguing differences between TBI and LKI, and suggest that urine proteome may be useful in determining organ-specific changes caused by partial body irradiation.
Self‐regulation strategies improve self‐discipline in adolescents: benefits of mental contrasting and implementation intentions

Adolescents struggle with setting and striving for goals that require sustained self‐discipline. Research on adults indicates that goal commitment is enhanced by mental contrasting (MC), a strategy involving the cognitive elaboration of a desired future with relevant obstacles of present reality. Implementation intentions (II), which identify the action one will take when a goal‐relevant opportunity arises, represent a strategy shown to increase goal attainment when commitment is high. This study tests the effect of mental contrasting combined with implementation intentions (MCII) on successful goal implementation in adolescents. Sixty‐six 2nd‐year high school students preparing to take a high‐stakes exam in the fall of their third year were randomly assigned to complete either a 30‐minute written mental contrasting with implementation intentions intervention or a placebo control writing exercise. Students in the intervention condition completed more than 60% more practice questions than did students in the control condition. These findings point to the utility of directly teaching to adolescents mental contrasting with implementation intentions as a self‐regulatory strategy of successful goal pursuit.
Experimental characterization of S-matrix reconstruction transforms on multiport networks

The characteristics of three existing S-matrix reconstruction transforms on the multiport network characterization are studied for the case of using a single kind of auxiliary terminations. Three unifying properties are discerned and experimentally verified. It is found that the three existing S-matrix transforms prefer auxiliary terminations with small reflection coefficients. When auxiliary terminations with large reflection coefficients are taken, it may encounter numerical difficulty whose destructiveness depends inversely on the power loss of the device under test. These findings may lead more studies on the cause and remedy of the numerical difficulty.
Replacing the Soft-Decision FEC Limit Paradigm in the Design of Optical Communication Systems

The FEC limit paradigm is the prevalent practice for designing optical communication systems to attain a certain bit error rate (BER) without forward error correction (FEC). This practice assumes that there is an FEC code that will reduce the BER after decoding to the desired level. In this paper, we challenge this practice and show that the concept of a channel-independent FEC limit is invalid for soft-decision bit-wise decoding. It is shown that for low code rates and high-order modulation formats, the use of the soft-decision FEC limit paradigm can underestimate the spectral efficiencies by up to 20%. A better predictor for the BER after decoding is the generalized mutual information, which is shown to give consistent post-FEC BER predictions across different channel conditions and modulation formats. Extensive optical full-field simulations and experiments are carried out in both the linear and nonlinear transmission regimes to confirm the theoretical analysis.
An adaptive change detection scheme for a nonlinear beam model

In this paper, we consider parameter estimation techniques for detecting changes of a nonlinear nature in an Euler-Bernoulli beam model. The nonlinear stiiness used provides a very simple model of damage, and the adaptive estimation algorithm is used to track the onset of the nonlinearity. Using Lyapunov redesign methods, extended and applied to innnite dimensional systems, a stable learning scheme is developed. The resulting parameter adaptation rule is able to \sense" the instance of the fault occurence. In addition, it identiies the location and the shape of the fault where the beam is persistently excited. Simulation studies are used to illustrate the applicability of the theoretical results.
Globular Cluster Systems in Brightest Cluster Galaxies: Bimodal Metallicity Distributions and the Nature of the High-Luminosity Clusters

We present new (B, I) photometry for the globular cluster systems in eight brightest cluster galaxies (BCGs), obtained with the ACS/WFC camera on the Hubble Space Telescope. In the very rich cluster systems that reside within these giant galaxies, we find that all have strongly bimodal color distributions that are clearly resolved by the metallicity-sensitive (B - I) index. Furthermore, the mean colors and internal color range of the blue subpopulation are remarkably similar from one galaxy to the next, to well within the ±0.02-0.03 mag uncertainties in the foreground reddenings and photometric zero points. By contrast, the mean color and internal color range for the red subpopulation differ from one galaxy to the next by twice as much as the blue population. All the BCGs show population gradients, with much higher relative numbers of red clusters within 5 kpc of their centers, consistent with their having formed at later times than the blue, metal-poor population. A striking new feature of the color distributions emerging from our data is that for the brightest clusters (MI < -10.5) the color distribution becomes broad and less obviously bimodal. This effect was first noticed by Ostrov et al. and Dirsch et al. for the Fornax giant NGC 1399; our data suggest that it may be a characteristic of many BCGs and perhaps other large galaxies. Our data indicate that the blue (metal-poor) clusters brighter than MI ≃ -10 become progressively redder with increasing luminosity, following a mass/metallicity scaling relation Z ~ M0.55. A basically similar relation has been found for M87 by Strader et al. (2005). We argue that these GCS characteristics are consistent with a hierarchical-merging galaxy formation picture in which the metal-poor clusters formed in protogalactic clouds or dense starburst complexes with gas masses in the range 107-1010 M☉, but where the more massive clusters on average formed in bigger clouds with deeper potential wells where more preenrichment could occur.
Path Planning for Mobile Robot Navigation using Voronoi Diagram and Fast Marching

This paper presents a new sensor based global path planner which operates in two steps. In the first step the safest areas in the environment are extracted by means of a Voronoi diagram. In the second step fast marching method is applied to the Voronoi extracted areas in order to obtain the shortest path. In this way the trajectory obtained is the shortest between the safe possible ones. This two step method combines an extremely fast global planner operating on a simple sensor based environment modeling, while it operates at the sensor frequency. The main characteristics are speed and reliability, because the map dimensions are reduced to a unidimensional map and this map represents the safest areas in the environment for moving the robot
Regulation of glucose transport in the NIH 3T3 L1 preadipocyte cell line by TCDD.

This study examined the changes in cellular glucose uptake induced by 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) as measured by quantification of intracellular radioactivity in the NIH 3T3 L1 preadipocyte cell line after a 30-minute incubation with the non-metabolizable radioactive analogue of glucose, 3-O-methyl-D-[1-3H] glucose. Treatment of differentiated NIH 3T3 L1 cells with TCDD produced a time- and dose-dependent decrease in the cellular uptake of glucose. Treatment of cells for 3 hr with 10(-8) M TCDD significantly reduced glucose uptake to about 10% of control values (p </= 0.05). Furthermore, cytochalasin B, a specific inhibitor of facilitative glucose transporter proteins totally abolished the portion of glucose transport activity that is sensitive to TCDD. The role of the Ah receptor in TCDD-mediated reduction in glucose uptake was investigated. Pretreatment of 3T3 L1 cells with the Ah receptor blocker 4,7-phenanthroline antagonized the effect of TCDD on glucose uptake. Structure-activity relationship studies with TCDD and two polychlorinated biphenyl (PCB) congeners revealed a rank order for their potency in the inhibition of glucose transport as follows: TCDD <<3,3',4,4' tetrachlorobiphenyl <2,2',5,5' tetrachlorobiphenyl (TCB). Such a rank order correlates both with previously determined biological activity of TCDD and the more active 3,3',4,4'- and less active 2,2',5,5'-TCB and with affinity for binding to the Ah receptor. The thyroid hormone T4, like TCDD, reduced glucose uptake and blocked the action of TCDD to further reduce glucose uptake. Experimental evidence is consistent with a proposed mechanism for TCDD to reduce the titer of functional glucose transporter proteins through its interaction with the Ah receptor. Imagesp454-aFigure 1.Figure 2.
Novel sizing algorithm for yield improvement under process variation in nanometer technology

Due to process parameter variations, a large variabilily in circuit delay occurs in scaled technologies affecting the yield. In this paper, we propose a sizing algorithm to ensure the speed of a circuit under process variation with a certain degree of confidence while maintaining the area and power budget within a limit. This algorithm estimates the variation in circuit delay using statistical timing analysis considering both inter-and intra-die process variation and resizes the circuit to achieve a desired yield. Experimental results on several benchmark circuits show that one can achieve up to 19% savings in area (power) using our algorithm compared to the worst-case design.
Bilingualism and Musicianship Enhance Cognitive Control

Learning how to speak a second language (i.e., becoming a bilingual) and learning how to play a musical instrument (i.e., becoming a musician) are both thought to increase executive control through experience-dependent plasticity. However, evidence supporting this effect is mixed for bilingualism and limited for musicianship. In addition, the combined effects of bilingualism and musicianship on executive control are unknown. To determine whether bilingualism, musicianship, and combined bilingualism and musicianship improve executive control, we tested 219 young adults belonging to one of four groups (bilinguals, musicians, bilingual musicians, and controls) on a nonlinguistic, nonmusical, visual-spatial Simon task that measured the ability to ignore an irrelevant and misinformative cue. Results revealed that bilinguals, musicians, and bilingual musicians showed an enhanced ability to ignore a distracting cue relative to controls, with similar levels of superior performance among bilinguals, musicians, and bilingual musicians. These results indicate that bilingualism and musicianship improve executive control and have implications for educational and rehabilitation programs that use music and foreign language instruction to boost cognitive performance.
Compositional Changes in Compost during Composting and Growth of Agaricus bisporus

Samples from conventional compost taken at various stages of composting and mushroom (Agaricus bisporus) growth were analyzed for changes in 80% ethanol and water extracts, monosaccharides in acid hydrolysates of polysaccharides, lignin concentration, and lignin structural features. Variable amounts of extraneous inorganic solids in the form of fine sandy particles were removed by sedimentation of the samples in a carbon tetrachloride-dibromomethane mixture. During composting, about two-thirds of the initial wall polysaccharides were consumed by compost microorganisms, and only 17% of the total polysaccharides were used during mushroom production. The relative lignin content of composts as measured by the acetyl bromide procedure increased, both during composting and mushroom growth, and the chemical structure of lignin was altered by condensation and oxidation reactions.
Presence-absence versus presence-only modelling methods for predicting bird habitat suitability

Habitat suitability models can be generated using methods requiring information on species presence or species presence and absence. Knowledge of the predictive performance of such methods becomes a critical issue to establish their optimal scope of application for mapping current species distributions under different constraints. Here, we use breeding bird atlas data in Catalonia as a working example and attempt to analyse the relative performance of two methods: the Ecological Niche factor Analysis (ENFA) using presence data only and Generalised Linear Models (GLM) using presence/absence data. Models were run on a set of forest species with similar habitat requirements, but with varying occurrence rates (prevalence) and niche positions (marginality). Our results support the idea that GLM predictions are more accurate than those obtained with ENFA. This was particularly true when species were using available habitats proportionally to their suitability, making absence data reliable and useful to enhance model calibration. Species marginality in niche space was also correlated to predictive accuracy, i.e. species with less restricted ecological requirements were modelled less accurately than species with more restricted requirements. This pattern was irrespective of the method employed. Models for wide-ranging and tolerant species were more sensitive to absence data, suggesting that presence/absence methods may be particularly important for predicting distributions of this type of species. We conclude that modellers should consider that species ecological characteristics are critical in determining the accuracy of models and that it is difficult to predict generalist species distributions accurately and this is independent of the method used. Being based on distinct approaches regarding adjustment to data and data quality, habitat distribution modelling methods cover different application areas, making it difficult to identify one that should be universally applicable. Our results suggest however, that if absence data is available, methods using this information should be preferably used in most situations.
Pulmonary function and circulating adhesion molecules in patients with diabetes mellitus.

BACKGROUND Lung function in diabetes has been reported in several studies with contradictory results. Diabetes mellitus increases expression of adhesion molecules through hyperglycemia. These molecules play an important role in the pathophysiological dysfunction of the vasculature. OBJECTIVE To explore the possible relationship between lung function and circulating levels of adhesion molecules in diabetes. METHODS Sixteen type 1 diabetic patients, 33 type 2 diabetic patients and 22 healthy subjects matched for age and sex were studied. Spirometry measurements were performed and pulmonary diffusion capacity for carbon monoxide (DLco) was measured in sitting and supine positions by the single-breath method corrected by alveolar volume (VA). Glycosylated hemoglobin, retinopathy and nephropathy were included as parameters of metabolic control and diabetic complications. Circulating levels of soluble E-selectin and vascular cell adhesion molecule-1 (VCAM-1) were determined in all subjects. RESULTS Diabetic subjects showed lower variation in DLco and DLco/VA by changing posture from sitting to supine position (P=0.043 and P<0.001, respectively), and showed reduced total lung capacity (P<0.001) and forced expiratory volume in 1 s/forced vital capacity (P=0.009) compared with healthy control subjects. Serum concentrations of E-selectin were elevated in diabetic patients (P<0.001). There was no difference in serum VCAM-1 concentrations between diabetic and control subjects. On stepwise regression analysis, E-selectin concentrations were the most important contributing factor to the variation in DLco/VA. CONCLUSIONS Diabetic patients show lower pulmonary volumes and variation in DLco by changing posture from sitting to supine position, and they also show increased levels of E-selectin. A possible explanation is impaired pulmonary microvasculature, because adhesion molecules seem to be sensitive markers of endothelial activation and damage seen in diabetes.
Predictors of psychopathology among Nigerian adolescents: the role of psychosocial, demographics, personality and medical condition reports domains.

BACKGROUND Psychopathology among adolescents has become a global concern in the last decade. OBJECTIVE The aim of this study was to identify the predictors of psychopathology among adolescents in Ibadan region using a multi-theoretical approach. METHODS Eight hundred and eighty-nine (889) male and female adolescents drawn from different parts of Ibadan region of the South-West Nigeria, participated in the study. The study is a cross-sectional survey and adopted an ex-post facto design. A questionnaire divided into six sections, with two versions was used for data collection. Analysis of data involved multiple/stepwise regressions, F-test & T-test. SPSS 10.0 computer programme was utilized for all analyses. RESULTS Data showed that all the predictors jointly contributed 37% (P<0.0001) to the prediction of reported psychopathology. The domains of psychosocial, personality, demographic and medical condition reports all independently and significantly predicted psychopathology among the adolescents but psychosocial domain had the highest contribution of 16% (P<0.0001). Prevalence rate for psychopathology among the sampled adolescents was 0.152 (15.2%) at the criteria of one standard deviation above the mean. CONCLUSION It is concluded that a multi-theoretical approach to the understanding of psychopathology among adolescents will be more appropriate in the Nigerian community. Results have implication for further assessment and treatments. Parents are advised to report any behavioural dysfunction observed in their wards to experts early enough to avoid degeneration to greater psychopathology in the later years.
Translocation of Incoming Pseudorabies Virus Capsids to the Cell Nucleus Is Delayed in the Absence of Tegument Protein pUL37

ABSTRACT After fusion of the envelope of herpesvirus particles with the host cell plasma membrane, incoming nucleocapsids are transported to nuclear pores. Inner tegument proteins pUL36, pUL37, and pUS3 remain attached to the nucleocapsid after entry and therefore might mediate interactions between the nucleocapsid and cellular microtubule-associated motor proteins during transport. To assay for the role of pUL37 in this process, we constructed a pUL37-deleted pseudorabies virus mutant, PrV-ΔUL37/UL35GFP, which expresses a fusion protein of green fluorescent protein (GFP) and the nonessential small capsid protein pUL35, resulting in the formation of fluorescently labeled capsids. Confocal laser-scanning microscopy of rabbit kidney cells infected with PrV-ΔUL37/UL35GFP revealed that, whereas penetration was not affected in the absence of pUL37, nuclear translocation of incoming particles was delayed by approximately 1 h compared to PrV-UL35GFP, but not abolished. In contrast, phenotypically complemented pUL37-containing virions of PrV-ΔUL37/UL35GFP exhibited wild type-like entry kinetics. Thus, the presence of pUL37 is required for rapid nuclear translocation of incoming nucleocapsids.
Differential Fay identities and auxiliary linear problem of integrable hiearchies

We review the notion of differential Fay identities and demonstrate, through case studies, its new role in integrable hierarchies of the KP type. These identities are known to be a convenient tool for deriving dispersionless Hirota equations. We show that differential (or, in the case of the Toda hierarchy, difference) Fay identities play a more fundamental role. Namely, they are nothing but a generating functional expression of the full set of auxiliary linear equations, hence substantially equivalent to the integrable hierarchies themselves. These results are illustrated for the KP, Toda, BKP and DKP hierarchies. As a byproduct, we point out some new features of the DKP hierarchy and its dispersionless limit.
Counteractive self-control in overcoming temptation.

How do anticipated short-term costs affect the likelihood of engaging in an activity that has long-term benefits. Five studies investigated the factors that determine (a) how anticipated short-term costs elicit self-control efforts and (b) how self-control efforts eventually diminish the influence of short-term costs on behavior. The studies manipulated short-term costs (e.g., painful medical procedures) and assessed a variety of self-control strategies (e.g., self-imposed penalties for failure to undergo a test). The results show that short-term costs elicit self-control strategies for self rather than others, before rather than after behavior. when long-term benefits are important rather than unimportant and when the costs are moderate rather than extremely small or large. The results also show that the self-control efforts help people act according to their long-term interests.
Modelling User Trust and Mobile Payment Adoption: A Conceptual Framework

The proliferation of new technologies and the changing dynamics of industry competition have spurred growth in innovative production, marketing and consumption. The need for convenience has also fuelled enormous interest in the use of mobile payment innovations, which in turn creates security challenges for users. Indications are that mobile phones and handheld devices should have made more inroads in businesses and societies as in most advanced societies are at today [1]. Instead, there has been a slow acceptance of mobile and handheld devices as alternative payment systems, especially in developing countries, despite the efforts of key players such as banks, mobile network operators, and mobile payment service providers (MPSP). This paper, therefore, is a conceptual design to examine security factors influencing the acceptance of mobile payment systems in Malaysia. This paper will examine the impact of security dimensions on trust and how these impacts on trust influence users’ intention to use mobile payment systems. We will also highlight several research, practitioner and policy implications.