Miracle-dz/UniFAR-FTUs huggingface dataset:
Music Educators’ Perceptions of Preparation and Supports Available for Inclusion

The purpose of this study was to investigate music educators’ perceptions of their educational preparation and the availability of instructional supports to work with students with disabilities in their classrooms/ensembles. Music educators (N = 1,128) representing all 50 United States responded to a survey fashioned after a similar instrument used by Gfeller, Darrow, and Hedden. Results indicated slight positive increases over the past two decades in regards to types of course offerings, in-service attendance and availability, involvement in the Individualized Education Program process, placement decisions, consultation with special education experts, and provision of adequate preparation time and resource materials/adaptive devices. Results also indicated that current music education practices (e.g., music-specific coursework, workshops, and in-services) created greater feelings of preparedness to work with students with disabilities and increased attendance at additional educational opportunities. The discussion includes further results and educational implications.
PRELIMINARY LITHOGEOCHEMISTRY AND POLYMETALLIC VHMS MINERALIZATION IN EARLY DEVONIAN AND ( ? ) EARLY CARBONIFEROUS VOLCANIC ROCKS , FOREMORE PROPERTY

The recent discovery on the Foremore property of new VHMS mineralization that contains significant precious metal values has caused resurgence in the exploration interests of Paleozoic volcanic rocks in northern British Columbia. VHMS deposits are well documented in Devonian and Early Carboniferous volcanic sequences at the Kudz Ze Kayah and Wolverine deposits in the southern Yukon (Yukon-Tanana terrane) and at the Tulsequah Chief deposit in northern British Columbia (Stikine terrane). Devono-Mississippian rocks of the Stikine terrane also host polymetallic mineralization at the Foremore property (Fig. 1).
Best practices of ICT workforce management – a comparable research initiative in Finland

This paper describes a project which investigates the human resource management practices that are being used in managing information professionals in ICT companies or ICT departments. The effectiveness of the practices is evaluated from individual and management perspectives. It is assumed that the nature of the contract between the IS professional and the organization influences the effectiveness of different practices. Thus, the notion of “best practice” is seen as context dependent. When writing the paper, the research was still in progress and no results can yet be given. After completing the study, practitioners can use the results to compare their own practices with those that were found to be effective in the nine case organizations. For researchers, the results will provide hypotheses about the relationship between HRM practices and job satisfaction of the IS professionals.
Laboratory aspects of Lyme borreliosis

Lyme borreliosis (Lyme disease), a common tick-borne disorder of people and domestic animals in North America and Europe, is caused by the spirochete Borrelia burgdorferi. Following the discovery and initial propagation of this agent in 1981 came revelations that other tick-associated infectious disorders are but different forms of Lyme borreliosis. A challenge for the clinician and microbiology laboratory is confirmation that a skin rash, a chronic meningitis, an episode of myocarditis, or an arthritic joint is the consequence of B. burgdorferi infection. The diagnosis of Lyme borreliosis may be established by (i) directly observing the spirochete in host fluid or tissue, (ii) recovering the etiologic spirochete from the patient in culture medium or indirectly through inoculation of laboratory animals, or (iii) carrying out serologic tests with the patient's serum or cerebrospinal fluid. The last method, while lacking in discriminatory power, is the most efficacious diagnostic assay for most laboratories at present.
Dystrophin expression in a Duchenne muscular dystrophy Patient with a frame shift deletion

Article abstract-The exon 45 deletion is a common dystrophin gene deletion. Although this is an out-of-frame deletion, which should not allow for protein synthesis, it has been observed in mildly affected patients. We describe a patient with an exon 45 deletion who produced protein, but still had a severe Duchenne muscular dystrophy phenotype. RT-PCR analysis and cDNA sequencing from the muscle biopsy sample revealed that the exon 45 deletion induced exon skipping of exon 44, which resulted in an in-frame deletion and the production of dystrophin. A conformational change in dystrophin induced by the deletion is proposed as being responsible for the severe phenotype in the patient. We feel that the variable clinical phenotype observed in patients with the exon 45 deletion is not due to exon splicing but may be the result of other environmental or genetic factors, or both. NEUROLOGY 1997;48: 486-488
Dynamic Global Games of Regime Change: Learning, Multiplicity and Timing of Attacks

Global games of regime change-coordination games of incomplete information in which a status quo is abandoned once a sufficiently large fraction of agents attack it-have been used to study crises phenomena such as currency attacks, bank runs, debt crises, and political change. We extend the static benchmark examined in the literature by allowing agents to take actions in many periods and to learn about the underlying fundamentals over time. We first provide a simple recursive algorithm for the characterization of monotone equilibria. We then show how the interaction of the knowledge that the regime survived past attacks with the arrival of information over time, or with changes in fundamentals, leads to interesting equilibrium properties. First, multiplicity may obtain under the same conditions on exogenous information that guarantee uniqueness in the static benchmark. Second, fundamentals may predict the eventual fate of the regime but not the timing or the number of attacks. Finally, equilibrium dynamics can alternate between phases of tranquility-where no attack is possible-and phases of distress-where a large attack can occur-even without changes in fundamentals. Copyright The Econometric Society 2007.
Promoting the Internationalization of Evidence-Based Practice: Benchmarking as a Strategy to Evaluate Culturally Transported Psychological Treatments

In addition to the growing evidence-based practice movement in psychology, psychological treatments are undergoing increasing adaptation and transportation to other countries and cultures around the world, prompting the need to evaluate treatments in these diverse settings. This article proposes the “benchmarking” strategy as a valuable approach to evaluate the effectiveness of culturally adapted or transported treatments and to promote the internationalization of evidence-based practice. We first describe the benchmarking concept in clinical research, followed by considerations for the cultural adaptation and transportation of psychological treatments. We then explain how the benchmarking strategy may be used to validate culturally transported and adapted psychological treatments. The article concludes with a discussion of considerations, limitations, and challenges for conducting cross-cultural benchmarking research.
Effects of Alcohol on Serial Learning under Stress Conditions

The dictum proposed by Jellinek and McFarland ( 1940) that "alcohol has a depressing effect on all psychological functions yet measured" is still generally accepted today. In another context Jellinek ( 1945 ) proposed an exception to this rule by conjecturing that in tense and anxiety-prone individuals alcohol may actually facilitate performance rather than inhibit it. The present study is concerned with a test of the hypothesis that under certain conditions (e.g., stress) alcohol increases efficiency in psychological performance instead of decreasing it. The term "stress" will be used here to denote a hypothetical state of a disruptive character induced by a describable but artificial stressor and having many physiological and behavioral concomitants. Stress may be considered as an experimental analogue to the personality dimensions discussed by Jellinek. If alcohol alleviates emotional tension as Greenberg and Carpenter have shown (1957), its effect on performance in a stress situation should be that of a stress counteractor. Once the disruptive effects of emotional tension on the performance of a task are checked, the efficiency of performance should increase. When this hypothesis is considered in conjunction with the ordinarily depressing action of alcohol, an interaction effect between alcohol and stress is predicted. Under stress conditions alcohol should facilitate learning, while inhibiting it under non-stress conditions.
The spectrum of antimicrobial activity of the bacteriocin subtilosin A.

BACKGROUND Bacterocins are antimicrobial peptides produced by bacteria with a relatively narrow range of activity against closely related organisms. Subtilosin A is a bacteriocin produced by Bacillus subtilis that has activity against Listeria monocytogenes, which might indicate antimicrobial activity unusual for bacteriocins. OBJECTIVES To examine the antimicrobial activity and factors affecting the activity of subtilosin A against a range of potentially pathogenic bacteria. METHODS The peptide was purified from cultures of B. subtilis and the MIC determined for 18 species of bacteria using a microdilution methodology. The extent of capsule formation was determined using microscopic examination of cells mounted in India ink. Protease mutants of a susceptible bacteria and mild heat shock were used to examine the effect of environmental stress on subtilosin A activity. RESULTS Subtilosin A proved to have antimicrobial activity against a wide range of bacteria including Gram-positive and Gram-negative bacteria and both aerobes and anaerobes. The peptide was less effective against capsulated forms of two Gram-negative bacteria than the non-capsulated strains of either. Heat shock but not protease activity also altered the effectiveness of the bacteriocin. CONCLUSIONS Subtilosin A has limited antimicrobial activity against a number of human pathogens which, combined with its relative ineffectiveness against some capsulated pathogens, may limit its usefulness as a human therapeutic.
Consumer Responses to Complex Advertisements: The Moderating Role of Need for Cognition, Knowledge, and Gender

Abstract This research attempts to isolate variables responsible for moderating the effectiveness of complex print advertisements. In a controlled experiment, the complexity of the target print advertisements was manipulated along four dimensions: visual, technical, lexical, and information complexity. Responses to these ads were elicited from a sample of 244 undergraduate students. The results suggest that the effectiveness of such an advertising strategy (i.e., use of complex advertisements) is indeed moderated by individual-difference variables such as need for cognition, knowledge, and gender. However, the extent and type of such influence seems to differ along the four dimensions of advertising complexity.
Adaptação do questionário de tarefas domésticas e de cuidado de irmãos

The aim of this study was to adapt the Household Responsibilities Questionnaire for the assessment of sibling care and household responsibilities among Brazilian adolescents. To do this, we carried out the translation and adaptation of items for the target population following the test-adaptation guidelines of the International Test Commission. Participants were 113 adolescents (61.9% female) with a mean age of 14.7 years (SD = 0.8) who answered the final version of the questionnaire. The set of items underwent principal axes analysis which revealed the two-factor solution as the most appropriate. The two factors, related to sibling care and household responsibilities, presented adequate alpha coefficients of 0.75 and 0.69 respectively. These results show evidence of construct validity for the questionnaire as well as reliability. Thus, this questionnaire enables systematic access to these phenomena, which can be critical to the advancement of knowledge and production of estimates at the national level.
Bullying involvement in primary school and common health problems

AIMS To examine the association of direct (e.g. hitting) and relational (e.g. hurtful manipulation of peer relationships) bullying experience with common health problems. METHODS A total of 1639 children (aged 6–9 years) in 31 primary schools were studied in a cross sectional study that assessed bullying with a structured child interview and common health problems using parent reports. Main outcome measures were common physical (e.g. colds/coughs) and psychosomatic (e.g. night waking) health problems and school absenteeism. RESULTS Of the children studied, 4.3% were found to be direct bullies, 10.2% bully/victims (i.e. both bully and become victims), and 39.8% victims. Direct bully/victims, victims, and girls were most likely to have physical health symptoms (e.g. repeated sore throats, colds, and coughs). Direct bully/victims, direct victims, and year 2 children were most likely to have high psychosomatic health problems (e.g. poor appetite, worries about going to school). Pure bullies (who never got victimised) had the least physical or psychosomatic health problems. No association between relational bullying and health problems was found. CONCLUSIONS Direct bullying (e.g. hitting) has only low to moderate associations with common health problems in primary school children. Nevertheless, health professionals seeing children with repeated sore throat, colds, breathing problems, nausea, poor appetite, or school worries should consider bullying as contributory factor. Key messages Bullying is widespread among primary school children. Many bullies are also victims of bullying At primary school age, the effects of bullying on health and school absenteeism are less strong than reported for secondary school children “Pure” bullies are healthier children compared to victims and bully/victims, suggesting that they have a constitution that allows them to be dominant in inappropriate ways Health professionals seeing children with repeated sore throat, colds and coughs, breathing problems, nausea, poor appetite or worries about going to school should consider bullying as contributory factor
The Forgotten Needle in My Collections: Task-Aware Ranking of Documents in Semantic Information Space

With the growing amount of content stored in personal and organizational information spaces, finding and re-finding documents becomes both more crucial and challenging. In this work, we propose an approach to reduce information overload in navigation by automatically focusing on important documents, adaptively to the tasks at hand. Based on the idea of managed forgetting, we present a ranking method, which unifies activity logs and semantic information about documents into a common framework to identify important documents to the user's current tasks. Our experiments on two real-world datasets, both collected from knowledge work activities in professional scenarios, show that our ranking approach outperforms the baseline methods for both subsequent access prediction and the effectiveness in ranking important documents. Furthermore, we implemented and demonstrated a system for decluttering information spaces as a proof of concept of our managed forgetting approach.
Nascent Synthesis of Leader Sequence-Containing Subgenomic mRNAs in Coronavirus Genome-Length Replicative Intermediate RNA

Abstract Infection with coronavirus results in the accumulation of genomic-sized mRNA and six to eight subgenomic mRNAs that make up a 3′ coterminal nested-set structure. Genome-length negative-strand RNA and subgenomic-length negative-strand RNAs, each of which corresponds to each of the subgenomic mRNAs, also accumulate in infected cells. The present study examined whether the genome-length negative-strand RNA serves as a template for subgenomic mRNA synthesis. Genome-length replicative intermediate (RI) RNA was purified by two-dimensional gel electrophoresis of intracellular RNAs from cells infected with mouse hepatitis virus. RNase A treatment of the purified genome-length RI resulted in the production of the genome-length replicative form RNA, indicating that the genome-length RI included genome-length template RNA. RNase protection assays using the purified genome-length RI and two probes, which corresponded to the 5′ 300-nt region of mRNA 6 and to the same region of mRNA 7, showed the presence of nascent leader sequence-containing subgenomic mRNAs in the genome-length RI. These data demonstrated that the genome-length negative-strand RNA serves as a template for subgenomic mRNA synthesis.
The Cognitive And Emotive Uses Of Forgiveness In The Treatment Of Anger

This article presents the cognitive and emotive uses of forgiveness as a psychotherapeutic technique which enables patients to release anger without inflicting harm on others. The benefits, process, and preventive uses of forgiveness in psychotherapy as well as obstacles encountered to relinquishing anger are discussed. The treatment of anger is one of the most important areas in psychotherapy, and its management is essential for both the emotional wellbeing of the individual and for the good of society. The number of reports (U.S. Department of Justice, 1981) on the increased expression of anger and violence against children, teachers, spouses, and others indicates that significant numbers of people in our society do not know how to deal appropriately with their anger. When anger develops, there are three mechanisms available for dealing with this emotion. These are denial, expression, and forgiveness; that is, the surrender of one’s desire for revenge.
Sts1 Plays a Key Role in Targeting Proteasomes to the Nucleus*

The evidence that nuclear proteins can be degraded by cytosolic proteasomes has received considerable experimental support. However, the presence of proteasome subunits in the nucleus also suggests that protein degradation could occur within this organelle. We determined that Sts1 can target proteasomes to the nucleus and facilitate the degradation of a nuclear protein. Specific sts1 mutants showed reduced nuclear proteasomes at the nonpermissive temperature. In contrast, high expression of Sts1 increased the levels of nuclear proteasomes. Sts1 targets proteasomes to the nucleus by interacting with Srp1, a nuclear import factor that binds nuclear localization signals. Deletion of the NLS in Sts1 prevented its interaction with Srp1 and caused proteasome mislocalization. In agreement with this observation, a mutation in Srp1 that weakened its interaction with Sts1 also reduced nuclear targeting of proteasomes. We reported that Sts1 could suppress growth and proteolytic defects of rad23Δ rpn10Δ. We show here that Sts1 suppresses a previously undetected proteasome localization defect in this mutant. Taken together, these findings explain the suppression of rad23Δ rpn10Δ by Sts1 and suggest that the degradation of nuclear substrates requires efficient proteasome localization.
Hidden digital watermarks in images

In this paper, an image authentication technique by embedding digital "watermarks" into images is proposed. Watermarking is a technique for labeling digital pictures by hiding secret information into the images. Sophisticated watermark embedding is a potential method to discourage unauthorized copying or attest the origin of the images. In our approach, we embed the watermarks with visually recognizable patterns into the images by selectively modifying the middle-frequency parts of the image. Several variations of the proposed method are addressed. The experimental results show that the proposed technique successfully survives image processing operations, image cropping, and the Joint Photographic Experts Group (JPEG) lossy compression.
The Conoid Associated Motor MyoH Is Indispensable for Toxoplasma gondii Entry and Exit from Host Cells

Many members of the phylum of Apicomplexa have adopted an obligate intracellular life style and critically depend on active invasion and egress from the infected cells to complete their lytic cycle. Toxoplasma gondii belongs to the coccidian subgroup of the Apicomplexa, and as such, the invasive tachyzoite contains an organelle termed the conoid at its extreme apex. This motile organelle consists of a unique polymer of tubulin fibres and protrudes in both gliding and invading parasites. The class XIV myosin A, which is conserved across the Apicomplexa phylum, is known to critically contribute to motility, invasion and egress from infected cells. The MyoA-glideosome is anchored to the inner membrane complex (IMC) and is assumed to translocate the components of the circular junction secreted by the micronemes and rhoptries, to the rear of the parasite. Here we comprehensively characterise the class XIV myosin H (MyoH) and its associated light chains. We show that the 3 alpha-tubulin suppressor domains, located in MyoH tail, are necessary to anchor this motor to the conoid. Despite the presence of an intact MyoA-glideosome, conditional disruption of TgMyoH severely compromises parasite motility, invasion and egress from infected cells. We demonstrate that MyoH is necessary for the translocation of the circular junction from the tip of the parasite, where secretory organelles exocytosis occurs, to the apical position where the IMC starts. This study attributes for the first time a direct function of the conoid in motility and invasion, and establishes the indispensable role of MyoH in initiating the first step of motility along this unique organelle, which is subsequently relayed by MyoA to enact effective gliding and invasion.
Coenzyme Q10 effects in neurodegenerative disease

Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial respiratory chain, and as a dietary supplement it has recently gained attention for its potential role in the treatment of neurodegenerative disease. Evidence for mitochondrial dysfunction in neurodegenerative disorders derives from animal models, studies of mitochondria from patients, identification of genetic defects in patients with neurodegenerative disease, and measurements of markers of oxidative stress. Studies of in vitro models of neuronal toxicity and animal models of neurodegenerative disorders have demonstrated potential neuroprotective effects of CoQ10. With this data in mind, several clinical trials of CoQ10 have been performed in Parkinson’s disease and atypical Parkinson’s syndromes, Huntington’s disease, Alzheimer disease, Friedreich’s ataxia, and amyotrophic lateral sclerosis, with equivocal findings. CoQ10 is widely available in multiple formulations and is very well tolerated with minimal adverse effects, making it an attractive potential therapy. Phase III trials of high-dose CoQ10 in large sample sizes are needed to further ascertain the effects of CoQ10 in neurodegenerative diseases.
GERONTOLOGICAL NURSING EDUCATION: A PROFESSIONAL AND PERSONAL CHALLENGE FOR FUTURE BACCALAUREATE FACULTY AND STUDENTS

Investigators in this study wanted to know if student nurses were increasing their factual knowledge and changing their attitudes about the elderly, as well as, desire to work with them. Respondents included two groups of undergraduates from a main campus (n = 87) and two from a satellite campus (n = 47) of a Baccalaureate College of Nursing (BSN) in a southern university during 1992‐1995. E. D. Palmore's (1990) quizzes (FAQ1, FAQ2, FAMHQ) were used as pre‐tests (upon entering the junior year) and post‐tests (upon completion of the senior year). E. D. Palmore's (1988) “documentation” and “classification” of items were used to calculate knowledge and attitude scores. Feelings about working with the elderly were part of demographic data, as were “determinants” in E. D. Palmore's (1982) “Theoretical Model. ” Mean scores within groups were by dependent t tests. Grand Means for comparison between campuses were by independent t Jests at a ≤ . 05 level of significance. Students from the main campus scored signific.