Miracle-dz/UniFAR-FTUs huggingface dataset:
Microsatellite instability, EpsteinÐBarr virus, mutation of type II transforming growth factor β receptor and BAX in gastric carcinomas in Hong Kong Chinese

Microsatellite instability (MI), the phenotypic manifestation of mismatch repair failure, is found in a proportion of gastric carcinomas. Little is known of the links between MI and Epstein–Barr virus (EBV) status and clinicopathological elements. Examination of genes mutated through the MI mechanism could also be expected to reveal important information on the carcinogenic pathway. Seventy-nine gastric carcinomas (61 EBV negative, 18 EBV positive) from local Hong Kong Chinese population, an intermediate-incidence area, were examined. Eight microsatellite loci, inclusive of the A10 tract of type II transforming growth factor β receptor (TβR-II), were used to evaluate the MI status. MI in the BAX and insulin-like growth factor II receptor (IGF-IIR) genes were also examined. High-level MI (>40% unstable loci) was detected in ten cases (12.7%) and low-level MI (1–40% unstable loci) in three (3.8%). High-level MI was detected in two EBV-associated cases (11%) and the incidence was similar for the EBV-negative cases (13%). The high-level MIs were significantly associated with intestinal-type tumours (P = 0.03) and a more prominent lymphoid infiltrate (P = 0.04). Similar associations were noted in the EBV-positive carcinomas. The highlevel MIs were more commonly located in the antrum, whereas the EBV-associated carcinomas were mostly located in body. Thirteen cardia cases were negative for both high-level MI and EBV. All patients aged below 55 were MI negative (P = 0.049). Of the high-level MIs, 80% had mutation in TβR-II, 40% in BAX and 0% in IGF-IIR. Of low-level MIs, 33% also had TβR-II mutation. These mutations were absent in the MInegative cases. Of three lymphoepithelioma-like carcinomas, two cases were EBV positive and MI negative, one case was EBV negative but with high-level MI. In conclusion, high-level MIs were present regardless of the EBV status, and were found in a particular clinicopathological subset of gastric carcinoma patient. Inactivation of important growth regulatory genes observed in these carcinomas confirms the importance of MI in carcinogenesis.
Dependency Satisfaction in Databases with Incomplete Information

Two of the major problems raised by information incompleteness in databases are how to evaluate queries and how to take data dependencies into account. We give a unified solution of these two intermingled problems for the relational model. Formal criteria for the correctness of the relational algebra and dependency satisfaction are presented. We give a correct redefinition of the complete relational algebra and present a method, called a chase, for enforcing a set of functional and full join dependencies on a relation with null-values of type "value exists, but is presently unknown". This novel chase can also be regarded as a generalization of previously known chase methods. The title of the paper reflects the emphasis of its contribution.
Simulating L-band emission of coniferous forests using a discrete model and a detailed geometrical representation

A discrete model, based on the radiative transfer theory, is used to simulate coniferous forest emissivity at L-band. Inputs to the model are given by using a detailed geometrical representation of Les Landes forest. Simulated emissivities are compared against EuroSTARRS campaign measurements, which were made over the same forest at nominally vertical polarization and several angles. The model has also been used to investigate the sensitivity of L-band radiometers to soil moisture under forests. Results of this investigation indicate that the soil contribution to emission is potentially appreciable, even under developed forests. This may be a useful result, in view of future satellite missions, such as SMOS and HYDROS
Factors that contribute to the educational success of Haitian‐American women

The purpose of this study was to explore the factors that contributed to the academic success of Haitian‐American women. This study was also conducted to determine if factors attributed to by academically successful Haitian women are related to selected demographic characteristics. Two hundred and thirteen Haitian women selected from the National Haitian Student Alliance, with at least a Bachelor’s degree, participated. They completed an online survey designed to elicit demographic information and their perception of the factors. Our results indicate that self‐motivation, financial assistance, access to resources, self‐perception and time management are among the most important factors that contributed to their academic success. Less important are community support and knowledge of a second language. Statistically significant relationships were found between a linear combination of the 16 success factors and only the following demographic characteristics: birthplace, years taken to complete college, father’s level of education and participant’s residence region.
A framework for implementing TQM in higher education programs

Purpose – This paper aims to provide a TQM framework that stresses continuous improvements in teaching as a plausible means of TQM implementation in higher education programs.Design/methodology/approach – The literature survey of the TQM philosophies and the comparative analysis of TQM adoption in industry versus higher education provide the theoretical and practical background for this work. The analysis of TQM in higher education was done considering various critical factors such as existing educational practices, the barriers of TQM and the return on investment (ROI) of TQM implementations. These explorations led to the development of a TQM framework that adopts Deming's wheel of Plan‐Do‐Check‐Act (PDCA) cycle for implementing continuous improvements in higher education programs.Findings – Unlike the scenario in industry, TQM philosophies have to be adapted suitably for a successful implementation in higher education. The proposed TQM framework with six core quality elements encompassing the seven‐step.
PSYCHOMETRIC PROPERTIES OF THE PERSIAN VERSION OF BECK ANXIETY INVENTORY (BAI)

Background : Measuring anxiety level in clinical and non-clinical population needs valid and reliable tool. This research examined the validity and reliability of Beck Anxiety Inventory in Iranian normal population as well as clinically anxious patients. Methods : First, a two-session course was run to train research workers. After they were sufficiently prepared, they were dispatched to different regions of the city, Tehran, referring to residential places for men and women volunteer to take part in the research. At the end, 1513 respondents were randomly recruited and tested using Beck Anxiety Inventory (BAI) . Of this population, 112 respondents were randomly selected and re-tested in order to measure test-retest reliability with a one-month interval time between first and second tests. Meanwhile, 261 clinically anxious patients (from clinics and mental health centers) were tested. In order to measure validity, 150 patients were interviewed by two parallel clinicians and the anxiety level was rated based on a 10 -point scale from 0 (the least) to 10 (the most). The two raters were blind to the BAI scores of the patients. Results : For data reduction and analysis, the SPSS for Windows-edition 14 , was conducted. Findings showed that the Persian version of BAI proved a good reliability (r =0.72 , p <0.001 ), a very good validity (r =0.83 , p <0.001 ), and an excellent internal consistency (Alpha =0.92 ). Conclusions: The results support the applicability of BAI in Iranian population and suggest the use of this inventory for clinical and research aims. Persian version of BAI not only can help clinicians in assessment and diagnosis, but also assist researchers to evaluate anxiety level when needed.
Response Styles and Personality Traits

In two studies, we examined the shared and unique meaning of acquiescent, extreme, midpoint, and socially desirable responding in association with the Occupational Personality Questionnaire (OPQ32), a forced-choice format personality measure designed to be less affected by these response styles, compared with personality inventories with Likert-type scales. Country-level response style indexes were derived from six waves of the International Social Survey Programme and from a meta-analysis of a social desirability scale. In the country-level correlational analysis, the four response styles formed a general response style (GRS) factor which was positively associated with (a) dominance (vs. submission) in interpersonal relationships, (b) competitive (vs. modest and democratic) feelings and emotions, and (c) data rational thinking. In a multilevel analysis, age showed a positive and education a negative effect on the individual-level GRS. Negative effects of country-level socioeconomic development and individualism and positive effects of competitiveness and data rational thinking on the individual-level response style were found. We conclude that country-level response styles are systematically associated with country personality measured by the OPQ32, suggesting that they can be viewed as having substantive meaning (i.e., culturally influenced response amplification vs. moderation). Implications are discussed.
A solution for changing the communication interfaces between WiFi and 3G without packet loss

The Internet Protocol (both IPv4 and IPv6) technology uses the IP address of the network interface as the identification of the communication session. The consequence of this idea is that the breakdown of the interface will also stop the communication session, even when other network interface cards would be available for the communication. Many of the currently used end devices (laptops, tablets, mobile phones) have usually more than one network interface cards (e.g. RJ-45, WiFi, 3G), which could be used for redundancy purposes. In this paper we investigate a software tool (named MPT library) which offers a solution in the Network Layer for keeping the communication session in the case of interface breakdown. We performed measurements in different business network environments for changing the WiFi and 3G network interfaces inside a communication session without losing a packet. These results confirm that the MPT multipath communication library can be used efficiently as a solution for the mentioned situation.
Conflict: Challenges and Mechanisms Head Teachers can use to Manage Conflict towards an improvement Teacher Morale in Public Primary Schools in Eldoret Municipality, Kenya

Improving employee morale benefits everyone in the workplace. Boosting employee morale means that people will take more pride in their work, call in sick less often and be more productive. Happier employees mean happier employers, since the employer will not lose money due to inefficiency and lost time. Improving employee morale can be accomplished fairly easy. Studies have shown managers spend 24 to 60 percent of their time on trying to solve employee disputes (Bell, 2002). Since individuals all comprise of different mindsets it’s quite possible that there may be arguments or differences of opinion regarding certain issues. You’ll find this happening most often in places of work. Usually there are different types of conflict but the ones causing most tense environments are those pertaining tom the office. This is so as most of our time is spent there. So where there are more people, and you spend more time, you are likely to engage in heated arguments as well. In many cases, conflict in the workplace just seems to be a fact of life.However, the role of the head teacher as pertaining conflict resolution is generally unknown. As such, the purpose of this study was to find out the challengeshead teacher’s face in conflict resolutions and to establish mechanism necessary in managing conflicts in schools without necessarily reducing teacher morale in the workplace. This study targeted head teachers and teachers in public primary schools in Eldoret Municipality who are believed to have worked in their stations for over a minimum of three years. The units for analysis for this study was be head teachers and teachers in public primary schools in Eldoret Municipality. The study adopted simple random, stratified and proportionate probability sampling techniques. The target population was 60 teachers and by sing simple random sampling the head teachers and teachers was stratified into stratas. Data collected was processed, coded and analyzed to facilitate answering the research questions. This was done using descriptive statistics. The study found out thatconflicts in the workplace are not solved because most of the head teachers are not capable of handling because they lack resolution skill and this hencelead to low teacher morale since no conflicts are effectively channeled in schools or organizations. This study therefore advocated for training and awareness of head teachers regarding conflict resolution processes.
Calibration and validation of the HY-2 scatterometer backscatter measurements over ocean

The Normalized Radar Cross-Sections (NRCS,σ0) measured by spaceborne scatterometer are used to determine the near-surface wind field using the geophysical model functions (GMF). The accuracy of the retrieved wind field is a sensitive function of the radiometric accuracy of the σ0 measurements. Therefore, in-orbit calibration is essential for the retrieval of optimum quality geophysical products. In this paper, the scatterometer onboard HY-2A satellite (HY-2 SCAT) is calibrated using Numerical Ocean Calibration (NOC) and its winds retrieval after calibration are validated by winds from global buoys and from the European Centre for Medium-Range Weather Foresting (ECMWF) Numerical Weather Prediction model (NWP). The standard deviations for wind speed and wind direction against buoy winds are better than 1.3 m/s and 15°, indicating that the HY-2 SCAT calibration has been successful and that HY-2 SCAT wind products after NOC are of high quality.
α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

We report the cloning and characterization of rat α10, a previously unidentified member of the nicotinic acetylcholine receptor (nAChR) subunit gene family. The protein encoded by the α10 nAChR subunit gene is most similar to the rat α9 nAChR, and both α9 and α10 subunit genes are transcribed in adult rat mechanosensory hair cells. Injection of Xenopus laevis oocytes with α10 cRNA alone or in pairwise combinations with either α2-α6 or β2-β4 subunit cRNAs yielded no detectable ACh-gated currents. However, coinjection of α9 and α10 cRNAs resulted in the appearance of an unusual nAChR subtype. Compared with homomeric α9 channels, the α9α10 nAChR subtype displays faster and more extensive agonist-mediated desensitization, a distinct current–voltage relationship, and a biphasic response to changes in extracellular Ca2+ ions. The pharmacological profiles of homomeric α9 and heteromeric α9α10 nAChRs are essentially indistinguishable and closely resemble those reported for endogenous cholinergic eceptors found in vertebrate hair cells. Our data suggest that efferent modulation of hair cell function occurs, at least in part, through heteromeric nAChRs assembled from both α9 and α10 subunits.
Separation-Free Super-Resolution from Compressed Measurements is Possible: an Orthonormal Atomic Norm Minimization Approach

We consider the problem of recovering the superposition of $R$ distinct complex exponential functions from compressed non-uniform time-domain samples. Total Variation (TV) minimization or atomic norm minimization was proposed in the literature to recover the $R$ frequencies or the missing data. However, it is known that in order for TV minimization and atomic norm minimization to recover the missing data or the frequencies, the underlying $R$ frequencies are required to be well-separated, even when the measurements are noiseless. This paper shows that the Hankel matrix recovery approach can super-resolve the $R$ complex exponentials and their frequencies from compressed non-uniform measurements, regardless of how close their frequencies are to each other. We propose a new concept of orthonormal atomic norm minimization (OANM), and demonstrate that the success of Hankel matrix recovery in separation-free super-resolution comes from the fact that the nuclear norm of a Hankel matrix is an orthonormal atomic norm. More specifically, we show that, in traditional atomic norm minimization, the underlying parameter values $\textbf{must}$ be well separated to achieve successful signal recovery, if the atoms are changing continuously with respect to the continuously-valued parameter. In contrast, for the OANM, it is possible the OANM is successful even though the original atoms can be arbitrarily close. As a byproduct of this research, we provide one matrix-theoretic inequality of nuclear norm, and give its proof from the theory of compressed sensing.
Efficacy of pegylated interferon and ribavirin combination therapy for patients with hepatitis C virus infection after curative resection or ablation for hepatocellular carcinoma—A retrospective multicenter study

The use of pegylated interferon (Peg‐IFN) plus ribavirin combination therapy for chronic hepatitis C patients who received curative treatment for hepatocellular carcinoma is controversial. This study tried to clarify this. Ninety‐nine chronic hepatitis C patients who received curative resection or radiofrequency ablation for primary hepatocellular carcinoma, met the Milan criteria and were treated with Peg‐IFN plus ribavirin therapy were enrolled (75 males, 24 females; mean age, 65.0 ± 5.9 years; 79 HCV genotype 1, 20 genotype 2). Among them, 40 patients who had received curative treatment for a single carcinoma were analyzed for recurrence (observation period: 27.6 ± 18.1 months). The factors associated with recurrence were examined using a log‐rank test and a Cox proportional‐hazards model. The discontinuation rate of the Peg‐IFN plus ribavirin combination therapy was 25% (25/99). Among the patients who completed the therapy, the sustained virologic response rates were 35% for the genotype 1 patients and 56% for the genotype 2 patients. The cumulative incidence rates of recurrence were 10.0% at 1 year and 40.8% at 3 years. On multivariate analysis, a virologic response and platelet counts served as independent factors of recurrence (sustained virologic response, hazard ratio = 0.190, P = 0.029; platelet counts <12 × 104/mm3, hazard ratio = 3.19, P = 0.019). It is concluded that patients with chronic hepatitis C virus infection after curative treatment for hepatocellular carcinoma can be candidates for anti‐viral therapy to reduce the recurrence of hepatocellular carcinoma, especially patients with low platelet counts. J. Med. Virol. 87:1199–1206, 2015. © 2015 Wiley Periodicals, Inc.
An Empirical Study on Web Service Evolution

The service-oriented architecture paradigm prescribes the development of systems through the composition of services, i.e., network-accessible components, specified by (and invoked through) their WSDL interface descriptions. Systems thus developed need to be aware of changes in, and evolve with, their constituent services. Therefore, accurate recognition of changes in the WSDL specification of a service is an essential functionality in the context of the software lifecycle of service-oriented systems. In this work, we present the results of an empirical study on WSDL evolution analysis. In the first part, we empirically study whether VTracker, our algorithm for XML differencing, can precisely recognize changes in WSDL documents by applying it to the task of comparing 18 versions of the Amazon EC2 web service. Second, we analyze the changes that occurred between the subsequent versions of various web-services and discuss their potential effects on the maintainability of service systems relying on them.
Kreativitas Siswa SMP yang Bergaya Kognitif Reflektif atau Impulsif dalam Memecahkan Masalah Geometri

Abstract: This research aim was describing a profile of students’ creativity with reflective or impulsive cognitive style in solving geometric problems. This research was explorative and qualitative. The subjects were junior high school students of reflective or impulsive cognitive styles measured by MFFT (Matching Familiar Figures Test). There were 10 subjects which consisted of 5 reflective and 5 impulsive students. This research resulted in the following: The creativity profile of students with reflective cognitive style in solving geometric problems tended to be high. The creativity profile of impulsive students in solving geometric problems tended to be very low. Keywords: creativity, problem solving, reflective, impulsive, and cognitive style. Abstrak: Penelitian ini bertujuan untuk menggambarkan profil kreativitas siswa yang bergaya kognitif reflektif atau impulsif dalam memecahkan masalah geometri. Jenis penelitian ini adalah eksploratif yang bersifat kualitatif. Subjek penelitian adalah siswa SMP yang bergaya kognitif reflektif atau impulsif yang diukur dengan MFFT (Matching Familiar Figures Test). Subjek penelitian ada 10 siswa, terdiri dari 5 siswa reflektif dan 5 siswa impulsif. Hasil penelitian adalah sebagai berikut: Profil kreativitas siswa yang bergaya kognitif reflektif dalam memecahkan masalah geometri cenderung tinggi. Dan profil kreativitas siswa impulsif dalam memecahkan masalah geometri cenderung sangat rendah. Kata Kunci: kreativitas, pemecahan masalah, reflektif, impulsif, dan gaya kognitif.
Knowledge Discovering using FrameNet, VerbNet and PropBank

In this paper, we present a high accurate system for FrameNet semantic role classification based on the innovative features derived from a combined use of FrameNet, VerbNet and PropBank. The main property of our approach is a unified view of the above three resources which is theoretically supported by the linking theory. Experiments on Support Vector Machines (SVM) show that our system classifies semantic information with high accuracy, enabling future work for the design of knowledge discovering FrameNet-based models.
Fibrinogen concentrate therapy in complex cardiac surgery.

OBJECTIVES Fibrinogen concentrate increasingly is used to treat coagulopathic bleeding in cardiac surgery although its effectiveness and safety have not been shown. The authors conducted a cohort study to quantify the effects of fibrinogen concentrate on postoperative blood loss and transfusion and the occurrence of adverse clinical events in complex cardiac surgery patients. DESIGN A cohort analysis using prospectively collected data. SETTING A teaching hospital. PARTICIPANTS One thousand seventy-five patients who underwent complex cardiac surgery in the years 2007 to 2010. INTERVENTION A nonrandomized intervention with fibrinogen concentrate during complex cardiac surgery. MEASUREMENTS AND MAIN RESULTS Of the 1,075 patients, 264 (25%) received fibrinogen concentrate during surgery (median dose = 2 g). In the adjusted analysis, the effect of fibrinogen concentrate on blood loss and transfusion in the intensive care unit showed a ratio of geometric means of 1.02 (0.91-1.14) and an odds ratio of 1.14 (0.83-1.56), respectively. For the risk of 30-day mortality, myocardial infarction, cerebrovascular accident/transient ischemic attack, renal insufficiency/failure, total infections, and prolonged mechanical ventilation the adjusted odds ratios were 0.96 (0.48-1.92), 1.10 (0.53-2.27), 1.16 (0.50-2.72), 0.62 (0.29-1.32), 1.18 (0.72-1.95), and 1.44 (0.83-2.49), respectively. CONCLUSIONS Fibrinogen concentrate infusion during surgery did not reduce postoperative blood loss and transfusion, and no increased risk for clinical adverse events was measured. The lower doses and the relatively late intervention with fibrinogen concentrate might have attenuated its hemostatic effect. This study reports the initial clinical use of fibrinogen concentrate in complex cardiac surgery. A randomized clinical trial has been initiated to investigate the hemostatic role of fibrinogen concentrate in cardiac surgery.