Miracle-dz/UniFAR-FTUs huggingface dataset:
Acute Psychophysiological Responses To Laboratory-Induced Stress In Different Groups: An Exploratory Study

Occupational stress has been broadly acknowledged as a global challenge and has been the focus of concern for many researchers as stress affects workers’ health and performance. Hence, the current study aimed to: a) assess psychophysiological stress among different occupational groups and b) identify differences, if any, between these groups using self-reports and heart rate variability (HRV) measures. Three different occupational groups (students; firefighters; air traffic controllers) of nine people in each group were analysed. The Trier Social Stress Test (TSST; Kirschbaum et al., 1993) was used as a stressinducer. Linear (HRV) features from participants’ electrocardiogram (ECG) were acquired using a medical-grade wearable ECG device (Vital Jacket®). Self-reports were also used before and after the stress task. Data were normalized to healthy populations, controlling for age and gender. ECG-derived normalized measures showed TSST induced stress arousal in all groups. Statistical significant differences were found in AVNN across the three groups using Kruskall-Wallis test, suggesting that the student group were more stressed compared to the other two groups. All the other HRV metrics (RMSSD, pNN50 and LF/HF), along with psychological stress results support these findings. An increase on stress selfperceptions was also found during the stress task. This study supports the idea that TSST is a gold standard stress procedure. Moreover, the use of bio-sensing platforms associated with the broad range of devices recently developed within the Internet of Things (IoT) field can be a valuable contribution for the development of “smart”; low-cost, simple and affordable quantified health technologies extended to a broad range of occupations. © 2018 Published by Future Academy www.FutureAcademy. org.UK
Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons

Background Zinc distributes widely in the central nervous system, especially in the hippocampus, amygdala and cortex. The dynamic balance of zinc is critical for neuronal functions. Zinc modulates the activity of N-methyl-D-aspartate receptors (NMDARs) through the direct inhibition and various intracellular signaling pathways. Abnormal NMDAR activities have been implicated in the aetiology of many brain diseases. Sustained zinc accumulation in the extracellular fluid is known to link to pathological conditions. However, the mechanism linking this chronic zinc exposure and NMDAR dysfunction is poorly understood. Methodology/Principal Findings We reported that chronic zinc exposure reduced the numbers of NR1 and NR2A clusters in cultured hippocampal pyramidal neurons. Whole-cell and synaptic NR2A-mediated currents also decreased. By contrast, zinc did not affect NR2B, suggesting that chronic zinc exposure specifically influences NR2A-containg NMDARs. Surface biotinylation indicated that zinc exposure attenuated the membrane expression of NR1 and NR2A, which might arise from to the dissociation of the NR2A-PSD-95-Src complex. Conclusions Chronic zinc exposure perturbs the interaction of NR2A to PSD-95 and causes the disorder of NMDARs in hippocampal neurons, suggesting a novel action of zinc distinct from its acute effects on NMDAR activity.
Analyzing the active audience: Reluctant, reactive, fearful, or lazy? Forms and motives of participation in mainstream journalism

Participation has become a key issue in contemporary journalism studies, yet research on how the participatory space is being appropriated by users is rather limited. This article attempts a methodological contribution by offering a way to analyze participatory journalism in reference to variant participatory affordances enabling different levels of creative effort, control, and editorial permeability. To do so, it understands participation as the active involvement of users, and makes an analytical connection among technological affordances, motivations, and contextual factors. The article offers empirical evidence challenging both cyber-optimist and cyber-pessimist assumptions about participation. Drawing on insights from a web-based survey, it is argued that the ‘reluctant audience’ paradigm may be interpreted in terms of the ‘lazy audience’ and the ‘fearful audience’, which seem to coexist along with the ‘reactive audience’.
Discrete maximum principle for higher-order finite elements in 1D

We formulate a sufficient condition on the mesh under which we prove the discrete maximum principle (DMP) for the one-dimensional Poisson equation with Dirichlet boundary conditions discretized by the hp-FEM. The DMP holds if a relative length of every element K in the mesh is bounded by a value H* rel (p) ∈ [0.9,1], where p ≥ 1 is the polynomial degree of the element K. The values H* rel (p) are calculated for 1 < p < 100.
Modal completeness of ILW

This paper contains a completeness proof for the system ILW, a rather bewildering axiom system belonging to the family of interpretability logics. We have treasured this little proof for a considerable time, keeping it just for ourselves. Johan’s fiftieth birthday appears to be the right occasion to get it out of our wine cellar.
Automated diagnosis of material condition in hammering test using a boosting algorithm

Automated diagnosis systems are necessary for the maintenance of superannuated social infrastructure. This paper presents a methodology for detecting material defects using acoustic signals in a hammering test. The approach comprises a feature extraction step using Short-Time Fourier Transform (STFT) and a classifier training step based on AdaBoost, an ensemble learning algorithm. Especially, we use weak learners based on a simple template matching method that can consider both the variable scale of amplitude and the variable frequency band. The experiments discriminate between defective and clean materials using different hammering test methods: rubbing and tapping.
Regulatory Arbitrage and International Bank Flows

We study whether cross-country differences in regulations have affected international bank flows. We find strong evidence that banks have transferred funds to markets with fewer regulations. This form of regulatory arbitrage suggests there may be a destructive “race to the bottom” in global regulations which restricts domestic regulators’ ability to limit bank risk-taking. However, we also find that the links between regulation differences and bank flows are significantly stronger if the recipient country is a developed country with strong property rights and creditor rights. This suggests that while differences in regulations have important influences, that without a strong institutional environment, lax regulations are not enough to encourage massive capital flows.
Enterprise system implementation in national and local Korean police agencies: a case study

Enterprise systems promise to bring various benefits to organizations. However, the dynamics of user adoption are not well understood, which makes fully realizing these expected benefits is challenging. A major difficulty arises from the fact that enterprise systems impose structures on adopting organizations based on best practices in the field, but users-in-context also influence the structure that is actually realized. In this study, structuration theory was adopted in order to examine the dynamics of human interactions with technological artifacts during technology use. From exploratory interview data regarding the use of On-Nara, the Korean government enterprise system, at the national and local police agencies, certain individual characteristics, institutional rules, and available technologies were found to affect the ways in which users enact On-Nara. Some users creatively modified certain functionalities of modules. Also, recursive use of On-Nara brought subtle changes to user practices by creating new processes of collective discussion, and by lessening the rigidity of hierarchy. Further, the system's original goals and the users' perception of the goals did not always match. Indeed, use of the system evolved with its own "spirit. " The study's findings will benefit both public and business organizations by providing insights regarding how users make sense of, and decide to actually use, features and functionalities of enterprise systems.
How Universal is the Gunn-Peterson Trough at z ~ 6?: A Closer Look at the Quasar SDSS J1148+5251

Detectable flux is visible in the Lyα and Lyβ troughs of the highest redshift (z = 6.42) quasar found to date, SDSS J1148+5251. This has previously been interpreted as continuum contamination from an interloper galaxy at z = 4.94. We examine the Lyγ trough of SDSS J1148+5251 and show that this interpretation is untenable: the spectrum does not show the continuum break in a z = 4.94 galaxy expected from absorption by the intervening Lyα forest. Therefore, flux must be leaking through at least one of the troughs from the quasar itself. Contrary to previous claims, the flux ratios in the Lyα and Lyβ troughs are consistent with pure transmission. From the Lyγ trough, we place an upper bound on the effective Lyα optical depth at z ~ 6.2 of τeff < 15.4 (2 σ). This implies a highly ionized intergalactic medium along this line of sight and significant cosmic variance in the transition toward complete Gunn-Peterson absorption.
Potential Susceptibility to Liver Dysfunction Induced by a Therapeutic Dose of Acetaminophen in Rats Submitted to Gestational and Lactational Protein Malnutrition

We investigated the potential susceptibility to liver dysfunction induced by a therapeutic dose of acetaminophen in rats submitted to gestational and lactational protein malnutrition using an animal model. Wistar rats were submitted to gestational and lactational protein malnutrition (control, 25% casein, and protein malnutrition, 7% casein). On the 10 th (P10) or on the 25 th (P25) a therapeutic dose of acetaminophen (15 mg/Kg, i.p.) was administered and rats were decapitated 6 hours after acetaminophen administration. Albumin content, Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) activities were measured in plasma, as well as the Glutathione (GSH) levels and Glutathione S-Transferase (GST) activity in liver. In both age groups, the treatment with acetaminophen decreased albumin levels and increased ALT and AST activities in plasma. It was also observed decreased hepatic GSH levels and increased GST activity just at P10. An acute therapeutic dose of acetaminophen may induce a mild liver dysfunction in protein malnutrition.
Lack of Cardiac Differentiation in c-kit-Enriched Porcine Bone Marrow and Spleen Hematopoietic Cell Cultures Using 5-Azacytidine

The adult spleen is a source of early hematopoietic stem cells (HSC). We therefore studied whether culturing spleen or bone marrow (BM) HSC in medium containing 5-azacytidine could induce a cardiac phenotype. c-kit enrichment and depletion of adult pig spleen and BM mononuclear cells were obtained by magnetic bead separation using biotinylated pig stem cell factor (c-kit ligand). Cells were incubated with 5-azacytidine for 24 h and refreshed with 5-azacytidine-free medium every 48 h. Western blot was used to detect cardiac troponin and myosin heavy chains. Although 5-azacytidine treatment led to the formation of ball-like cell clusters in both c-kit-enriched populations, these clusters showed no rhythmic contractions (beating), as observed by others. Furthermore, neither cardiac troponin nor myosin was detected in cells derived from either source. Our methodology and treatment with 5-azacytidine did not induce cardiac gene expression in porcine HSC derived from either pig spleen or BM.
T-Cadherin Expression in Melanoma Cells Stimulates Stromal Cell Recruitment and Invasion by Regulating the Expression of Chemokines, Integrins and Adhesion Molecules

T-cadherin is a glycosyl-phosphatidylinositol (GPI) anchored member of the cadherin superfamily involved in the guidance of migrating cells. We have previously shown that in vivo T-cadherin overexpression leads to increased melanoma primary tumor growth due to the recruitment of mesenchymal stromal cells as well as the enhanced metastasis. Since tumor progression is highly dependent upon cell migration and invasion, the aim of the present study was to elucidate the mechanisms of T-cadherin participation in these processes. Herein we show that T-cadherin expression results in the increased invasive potential due to the upregulated expression of pro-oncogenic integrins, chemokines, adhesion molecules and extracellular matrix components. The detected increase in chemokine expression could be responsible for the stromal cell recruitment. At the same time our previous data demonstrated that T-cadherin expression inhibited neoangiogenesis in the primary tumors. We demonstrate that T-cadherin overexpression leads to the increase in the expression of anti-angiogenic molecules and reduction in pro-angiogenic factors. Thus, T-cadherin plays a dual role in melanoma growth and progression: T-cadherin expression results in anti-angiogenic effects in melanoma, however, this also stimulates transcription of genes responsible for migration and invasion of melanoma cells.
Period Changes in ω Centauri RR Lyrae Stars

A century of observations of ω Centauri allows us to accurately follow the period changes of a large sample of variable stars. Although the period changes are composed of monotone and irregular changes, period increases dominate in most of the RRab stars. The typical period increase rates are of the same order of magnitude as model calculations predict for the evolved, redward phase of horizontal-branch evolution. For the 44 well-observed RRab stars that show monotonic period changes, a mean rate of 0.15 days Myr-1 has been found. The period changes of the first-overtone RRc-type stars show a much more complex, irregular behavior.
Linking individuation and organizational identification: Mediation through psychological safety

ABSTRACT This paper examines how individuation, a view that organizational members are all unique individuals, induces a perception of psychological safety and how perception of psychological safety, in turn, increases one’s organizational identification. Results from 66 respondents in Study 1 provided first support for the proposed mechanism. In Study 2, data collected from 176 employees in work organizations also provided evidence for this mediation model. It was found in both studies that individuation has a significantly positive association with the perception of psychological safety such that the more employees view individual members of the organization as unique individuals, the more likely they perceive that their organization is a safe environment for self-expression. Furthermore, perception of psychological safety was found to serve as a mediator linking individuation and organizational identification.
Initial retrieval shields against retrieval-induced forgetting

Testing, as a form of retrieval, can enhance learning but it can also induce forgetting of related memories, a phenomenon known as retrieval-induced forgetting (RIF). In four experiments we explored whether selective retrieval and selective restudy of target memories induce forgetting of related memories with or without initial retrieval of the entire learning set. In Experiment 1, subjects studied category-exemplar associations, some of which were then either restudied or retrieved. RIF occurred on a delayed final test only when memories were retrieved and not when they were restudied. In Experiment 2, following the study phase of category-exemplar associations, subjects attempted to recall all category-exemplar associations, then they selectively retrieved or restudied some of the exemplars. We found that, despite the huge impact on practiced items, selective retrieval/restudy caused no decrease in final recall of related items. In Experiment 3, we replicated the main result of Experiment 2 by manipulating initial retrieval as a within-subject variable. In Experiment 4 we replicated the main results of the previous experiments with non-practiced (Nrp) baseline items. These findings suggest that initial retrieval of the learning set shields against the forgetting effect of later selective retrieval. Together, our results support the context shift theory of RIF.
The Effect of Insulin Resistance on Prognosis of Non-Diabetic Patients Who Underwent Percutaneous Coronary Intervention

Insulin resistance is an important risk factor for coronary artery disease. However, there has been no data regarding its clinical effect on the outcomes of percutaneous coronary intervention (PCI) in non-diabetic patients. We analyzed 98 non-diabetic consecutive patients (59±11.5 yr, male:female=63:35) who underwent elective coronary angiography. The patients were divided into two groups: Group I (n=71; the value of HOMA-IR [homeostasis model assessment of insulin resistance] <2.6) and Group II (n=27; the value of HOMA-IR ≥2.6). In-hospital and 30-day major adverse cardiac events (MACE) were compared between the two groups. The concentrations of fasting insulin and triglyceride were significantly higher in Group II than in Group I. Significant correlations were observed between the value of HOMA-IR and body mass index (r=0.489, p<0.001), levels of total cholesterol (r=0.204, p=0.045), triglyceride (r=0.334, p=0.001) and apolipoprotein B (r=0.212, p=0.038). PCI was performed in 59 patients (60.2%). In-hospital and 30-day MACE were higher in Group II than Group I (2.4% vs. 27.8%, p=0.008; 2.4% vs. 27.8%, p=0.008). Multivariate analysis revealed that the value of HOMA-IR ≥2.6 was an independent predictor of MACE. Increased HOMA-IR level is an important prognostic indicator in non-diabetic patients underwent PCI.
RANDOM PERTURBATION OF THE VARIABLE METRIC METHOD FOR UNCONSTRAINED NONSMOOTH NONCONVEX OPTIMIZATION

We consider the global optimization of a nonsmooth (nondifferentiable) nonconvex real function. We introduce a variable metric descent method adapted to nonsmooth situations, which is modified by the incorporation of suitable random perturbations. Convergence to a global minimum is established and a simple method for the generation of suitable perturbations is introduced. An algorithm is proposed and numerical results are presented, showing that the method is computationally effective and stable.
Bio-Diesel from Mustard Oil: A Renewable Alternative Fuel for Small Diesel Engines

This paper represents the prospect of mustard oil as a renewable and alternative fuel. To cope up with present load-shedding situation and to reduce the dependency on imported fuel, Bangladesh government is encour- aging the use of renewable energy sources. Since diesel engines have versatile uses including small irrigation pumping systems, and standby small electricity generators, use of diesel fuel is much higher than any other gasoline fuels. In Bangladesh mustard oil has been in use as edible oil throughout the country. Mustard is a widely growing plant in Bangladesh and every year the production of mustard seed exceeds the demand. So the endeavor was to use the surplus mustard oil as an alternative to diesel fuel. Fuel properties are determined in the fuel testing laboratory with standard procedure. An experimental set-up is then made to study the performance of a small diesel engine in the heat engine laboratory using different blends of bio-diesel converted from mustard oil. It is found that bio-diesel has slightly different properties than diesel fuel. It is also observed that with bio-diesel, the engine is capable of running without difficulty but with a deviation from its optimum performance. Initially different blends of bio-diesel (i.e. B20, B30, B50 etc,) have been used to avoid complicated modification of the engine or the fuel supply system. Finally, a comparison of engine performance for different blends of bio-diesel has been carried out to determine the optimum blend for different operating conditions.
Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.

Numerous congenital malformations have been observed in fetuses of vitamin A-deficient (VAD) dams [Wilson, J. G. , Roth, C. B. , Warkany, J., (1953), Am. J. Anat. 92, 189-217]. Previous studies of retinoic acid receptor (RAR) mutant mice have not revealed any of these malformations [Li, E. , Sucov, H. M. , Lee, K. -F. , Evans, R. M. , Jaenisch, R. (1993) Proc. Natl. Acad. Sci. USA 90, 1590-1594; Lohnes, D. , Kastner, P., Dierich, A. , Mark, M. , LeMeur, M. , Chambon, P. (1993) Cell 73, 643-658; Lufkin, T. , Lohnes, D. , Mark, M. , Dierich, A. , Gorry, P., Gaub, M. P., Lemeur, M. , Chambon, P. (1993) Proc. Natl. Acad. Sci. USA 90, 7225-7229; Mendelsohn, C. , Mark, M. , Dollé, P., Dierich, A. , Gaub, M.P., Krust, A. , Lampron, C. , Chambon, P. (1994a) Dev. Biol. in press], suggesting either that there is a considerable functional redundancy among members of the RAR family during ontogenesis or that the RARs are not essential transducers of the retinoid signal in vivo. In order to discriminate between these possibilities, we have generated a series of RAR compound null mutants. These RAR double mutants invariably died either in utero or shortly after birth and presented a number of congenital abnormalities, which are reported in this and in the accompanying study. We describe here multiple eye abnormalities which are found in various RAR double mutant fetuses and are similar to those previously seen in VAD fetuses. Interestingly, we found further abnormalities not previously reported in VAD fetuses. (ABSTRACT TRUNCATED AT 250 WORDS)
Burden and Depressive Symptoms Associated with Adult-Child Caregiving for Individuals with Heart Failure

Background. The primary purpose of this study was to investigate adult-child caregiver burden in heart failure (HF) patients. Secondary purpose of the study was to identify the possible influencing factors for caregiver burden and depressive symptoms in a young adult-child caregiver group. Methods. A total of 138 adult-child caregivers and 138 patients with HF participated in this study. Caregivers' burden, depressive symptoms, and anxiety levels were assessed by using Zarit Caregiver Burden Scale (ZCBS), Beck Depression Inventory, and State-Trait Anxiety Inventory, respectively. Results. The mean ZCBS scores of the female caregivers were significantly higher than male caregivers. Approximately one-third of the adult-child caregivers had at least mild depressive symptoms. Caregivers with higher depressive symptoms had higher levels of caregiver burden. There were positive correlations between caregiving time, severity of depressive symptoms, and perceived caregiver burden. There was a negative correlation between education level of caregivers and perceived caregiver burden. Age, socioeconomic level, and marital status of patients were affecting factors for depressive symptoms in caregivers. Among caregiver characteristics, gender, marital status, and ZCBS scores seem to influence the depression in caregivers. Conclusions. The study findings suggest significant levels of burden and depressive symptoms even in adult-child caregivers of HF patients.