Miracle-dz/UniFAR-FTUs huggingface dataset:
Survival After Open Versus Endovascular Thoracic Aortic Aneurysm Repair in an Observational Study of the Medicare Population

Background— The goal of this study was to describe short- and long-term survival of patients with descending thoracic aortic aneurysms (TAAs) after open and endovascular repair (TEVAR). Methods and Results— Using Medicare claims from 1998 to 2007, we analyzed patients who underwent repair of intact and ruptured TAA, identified from a combination of procedural and diagnostic International Classification of Disease, ninth revision, codes. Our main outcome measure was mortality, defined as perioperative mortality (death occurring before hospital discharge or within 30 days), and 5-year survival, from life-table analysis. We examined outcomes across repair type (open repair or TEVAR) in crude, adjusted (for age, sex, race, procedure year, and Charlson comorbidity score), and propensity-matched cohorts. Overall, we studied 12 573 Medicare patients who underwent open repair and 2732 patients who underwent TEVAR. Perioperative mortality was lower in patients undergoing TEVAR compared with open repair for both intact (6.1% versus 7.1%; P=0.07) and ruptured (28% versus 46%; P<0.0001) TAA. However, patients with intact TAA selected for TEVAR had significantly worse survival than open patients at 1 year (87% for open, 82% for TEVAR; P=0.001) and 5 years (72% for open; 62% for TEVAR; P=0.001). Furthermore, in adjusted and propensity-matched cohorts, patients selected for TEVAR had worse 5-year survival than patients selected for open repair. Conclusions— Although perioperative mortality is lower with TEVAR, Medicare patients selected for TEVAR have worse long-term survival than patients selected for open repair. The results of this observational study suggest that higher-risk patients are being offered TEVAR and that some do not benefit on the basis of long-term survival. Future work is needed to identify TEVAR candidates unlikely to benefit from repair.
The Suppression and Justification of Prejudice as A Function of Political Orientation

Politically conservative (versus liberal) individuals generally report more prejudice towards various low–status out–groups. Three studies examined whether prejudice suppression factors—specifically, internal and external motivation to suppress (IMS and EMS, respectively) prejudice—can help explain the relationship between political orientation and prejudice. Study 1 showed that IMS and EMS partially mediated the relationship between political orientation and affective prejudice towards Arabs. Study 2 demonstrated that when justification [right–wing authoritarianism (RWA) and social dominance orientation] and suppression (IMS and EMS) factors are simultaneously tested as mediators, only RWA partially mediated the relationship between political orientation and prejudice towards deviant (e.g. gay men) out–groups, whereas RWA and IMS fully mediated the relationship between political orientation and prejudice towards derogated out–groups (e.g. Blacks). Intriguingly, IMS rendered social dominance orientation effects non–significant for derogated out–groups. Study 3 showed that anticipating an out–group interaction (with a Black or lesbian confederate) diminished the mediational contribution of IMS in the political orientation–prejudice relationship because of increased IMS among participants; yet the increases in IMS did not completely eliminate differences in prejudice as a function of political orientation. Ultimately, these three studies demonstrate that suppression (in addition to justification) factors do help explain the relationship between political orientation and prejudice. Copyright © 2013 European Association of Personality Psychology.
The association between breastfeeding and the cardiovascular system in early childhood.

BACKGROUND Breastfeeding is suggested to have beneficial effects on children's health and future health status. However, its cardiovascular effects in childhood and possibly later in life remain largely unclear. OBJECTIVE The aim of the present study was to determine the cardiovascular effects of exclusive breastfeeding in early childhood. DESIGN We used the ongoing WHeezing Illnesses STudy LEidsche Rijn (WHISTLER) birth cohort to obtain data on infant feeding. In the first 306 children who were 5 y of age, ultrasonographic measurements of the carotid artery were performed to obtain carotid intima-media thickness (CIMT), distensibility, and elastic modulus. RESULTS At 5 y of age, children who had been exclusively breastfed in infancy for 3 to 6 mo had a CIMT that was 21.1 μm greater than that of exclusively formula-fed children (95% CI: 5.0, 37.2 μm; P = 0.01, adjusted for confounders). CIMT was not significantly different between children exclusively breastfed for either <3 or >6 mo and formula-fed children. In addition, no significant differences in carotid stiffness were observed between groups. CONCLUSIONS The duration of exclusive breastfeeding in infancy is related to properties of the carotid arterial wall at the age of 5 y, as shown by the greater CIMT in children who were exclusively breastfed for 3 to 6 mo. This relation was independent of early growth in infancy and current cardiovascular disease risk factors. The choice of infant feeding appears to have an effect on the vascular system already in early childhood.
Holographic currents in first order Gravity and finite Fefferman-Graham expansions

We study the holographic currents associated to Chern-Simons theories. We start with an example in three dimensions and find the holographic representations of vector and chiral currents reproducing the correct expression for the chiral anomaly. In five dimensions, Chern-Simons theory for AdS group describes first order gravity and we show that there exists a gauge fixing leading to a finite Fefferman-Graham expansion. We derive the corresponding holographic currents, namely, the stress tensor and spin current which couple to the metric and torsional degrees of freedom at the boundary, respectively. We obtain the correct Ward identities for these currents by looking at the bulk constraint equations.
Artificial Neural Network in Drug Delivery and Pharmaceutical Research

Artificial neural networks (ANNs) technology models the pattern recognition capabilities of the neural networks of the brain. Similarly to a single neuron in the brain, artificial neuron unit receives inputs from many external sources, processes them, and makes decisions. Interestingly, ANN simulates the biological nervous system and draws on analogues of adaptive biological neurons. ANNs do not require rigidly structured experimental designs and can map functions using historical or incomplete data, which makes them a powerful tool for simulation of various non-linear systems.ANNs have many applications in various fields, including engineering, psychology, medicinal chemistry and pharmaceutical research. Because of their capacity for making predictions, pattern recognition, and modeling, ANNs have been very useful in many aspects of pharmaceutical research including modeling of the brain neural network, analytical data analysis, drug modeling, protein structure and function, dosage optimization and manufacturing, pharmacokinetics and pharmacodynamics modeling, and in vitro in vivo correlations. This review discusses the applications of ANNs in drug delivery and pharmacological research.
The Categorisation of Non-Categorical Colours: A Novel Paradigm in Colour Perception

In this paper, we investigate a new paradigm for studying the development of the colour ‘signal’ by having observers discriminate and categorize the same set of controlled and calibrated cardinal coloured stimuli. Notably, in both tasks, each observer was free to decide whether two pairs of colors were the same or belonged to the same category. The use of the same stimulus set for both tasks provides, we argue, an incremental behavioural measure of colour processing from detection through discrimination to categorisation. The measured data spaces are different for the two tasks, and furthermore the categorisation data is unique to each observer. In addition, we develop a model which assumes that the principal difference between the tasks is the degree of similarity between the stimuli which has different constraints for the categorisation task compared to the discrimination task. This approach not only makes sense of the current (and associated) data but links the processes of discrimination and categorisation in a novel way and, by implication, expands upon the previous research linking categorisation to other tasks not limited to colour perception.
Classifying and explaining democracy in the Muslim world

The purpose of this study is to classify and explain democracies in the 47 Muslim countries between the years 1998 and 2008 by using liberties and elections as independent variables. Specifically focusing on the context of the Muslim world, this study examines the performance of civil liberties and elections, variation of democracy practised the most, the elections, civil liberties and democratic transitions and patterns that followed. Based on the quantitative data primarily collected from Freedom House, this study demonstrates the following aggregate findings: first, the “not free not fair” elections, the “limited” civil liberties and the “Illiberal Partial Democracy” were the dominant feature of elections, civil liberties and democracy practised in the Muslim world; second, a total of 413 Muslim regimes out of 470 (47 regimes x 10 years) remained the same as their democratic origin points, without any transitions to a better or worse level of democracy, throughout these 10 years; and third, a slow, yet steady positive transition of both elections and civil liberties occurred in the Muslim world with changes in the nature of elections becoming much more progressive compared to the civil liberties’ transitions.
Process Optimization of Integrated SiCr Thin-Film Resistor for High-Performance Analog Circuits

We investigated the characteristic variation of an integrated thin-film resistor (TFR), which is composed of silicon chromium (SiCr), according to process conditions and its effects on analog circuits. To improve TFR properties, such as temperature coefficient of resistance (TCR) and mismatch, the integrated TFR was examined under various process conditions. First, the sputtering power and the annealing temperature were optimized to control the TCR property. Secondly, the etching time and the dummy pattern were optimized to enhance the mismatch property. The measured TCR is -3.9 ppm/°C and the calculated mismatch slope from the standard deviation of resistance mismatch is 0.34%·μm. These results show that the fabricated TFR had near-zero TCR and a high matching constant. To verify the TFRs effects on analog circuits, low-pass filters (LPFs) were fabricated and measured as a test vehicle; the use of the optimized resistor considerably improved the performance of the resulting LPFs.
Monitoring Attitude Change in Students to Teaching and Learning in a University Setting: a study using Perry's developmental model

Abstract We have studied whether changes brought about in the first year biology course at the University of Glasgow made any difference in students' attitudes to the way they learn. Students' attitudes were monitored with respect to the way they reacted or adapted to these changes using the Perry model of intellectual and ethical development. This model shows how students develop from a simplistic stance on the nature of knowledge to one which is more pluralistic and contextual. The results showed that the changes made to the course did make an impact on how the students learn and indicated that students were encouraged to learn autonomously. The results therefore have implications for some of the ways in which autonomy can be observed in students and also offers an insight which is of direct relevance to teachers who wish to plan courses which pursue autonomous learning.
When Does a Higher Construal Level Increase or Decrease Indulgence? Resolving the Myopia versus Hyperopia Puzzle

Existing inquiry on self-control reveals an inconsistency. The mainstream research on myopic behavior suggests that consumers' use of a high versus low construal level should lead them to exhibit less indulgence. However, more recent work on hyperopia implies the opposite. This research attempts to resolve this discrepancy. In particular, it is proposed and demonstrated that the level at which a consumer construes information (i.e., abstract vs. concrete), interacts with his or her self-focus, and both factors jointly determine a consumer's indulgence level. When the self is not salient, outcomes implied by the myopia literature ensue. But when the self is focal, the opposite outcomes anticipated by the hyperopia literature obtain.
Enhanced Selenate Accumulation in Cupriavidus metallidurans CH34 Does Not Trigger a Detoxification Pathway

ABSTRACT Cupriavidus metallidurans CH34 cells grown under sulfate-limited conditions accumulated up to six times more selenate than cells grown in sulfate-rich medium. The products of selenate reduction detected by X-ray absorption spectroscopy, electron microscopy, and energy-dispersive X-ray analysis did not define this strain as being a good candidate for bioremediation of selenate-contaminated environments.
Nucleotide Sequence of the Capsid Protein Gene of Plum Pox Potyvirus

SUMMARY The sequence of 1232 nucleotides from the 3' region of the plum pox virus (PPV) RNA has been determined. This sequence contains one long open reading frame (ORF). The sequence of the 17 amino-terminal amino acids of the PPV capsid protein was determined chemically. An identical amino acid sequence was found in the translation product of the large ORF, starting at amino acid - 330, which is alanine. Our data suggest that the PPV capsid protein, like that of other potyviruses, is a product of the maturation of a large polyprotein. The putative cleavage site is at a glutamine-alanine dipeptide. The capsid protein gene consists of 990 nucleotides and corresponds to a region coding for 330 amino acids which have a combined calculated Mr of 36593. The adjacent 3' untranslated region is of 215 nucleotides and ends in a polyadenylate tract. PPV capsid protein molecules are thus larger than those of the other potyviruses that have been characterized. The amino acid sequence of PPV coat protein is 47 to 60~ homologous to other potyvirus coat proteins and most of the variations are in the amino-terminal region.
Self‐Promotion Statements in Video Resumes: Frequency, Intensity, and Gender Effects on Job Applicant Evaluation

Although video resumes have received a substantial amount of media attention and there seems to be a growing awareness among Human Resource professionals of video‐based job applications, little is known about the effect of video resumes on applicant evaluation. This research investigates the effectiveness of self‐promotion within the context of video resumes. Self‐promotion frequency and intensity and applicant gender were manipulated. Ratings by recruiters and college students indicate that high levels of self‐promotion in video resumes are ineffective for male applicants and potentially detrimental for female applicants. Job applicants should use caution when attempting to promote themselves using video resumes. More research is needed on impression management tactics used at the earliest stages of selection and on the mechanisms operating within video resumes that impact applicant evaluation.
Design of a recognition system to predict movement during anesthesia

The need for a reliable method of predicting movement during anesthesia has existed since the introduction of anesthesia. This paper proposes a recognition system, based on the autoregressive (AR) modeling and neural network analysis of the electroencephalograph (EEG) signals, to predict movement following surgical stimulation. The input to the neural network will be the AR parameters, the hemodynamic parameters blood pressure (BP) and heart rate (HR), and the anesthetic concentration in terms of the minimum alveolar concentration (MAC). The output will be the prediction of movement. Design of the system and results from the preliminary tests on dogs are presented here. The experiments were carried out on 13 dogs at different levels of halothane. Movement prediction was tested by monitoring the response to tail clamping, which is considered to be a supramaximal stimulus in dogs. The EEG data obtained prior to tail clamping was processed using a tenth-order AR model and the parameters obtained were used as input to a three-layer perceptron feedforward neural network. Using only AR parameters the network was able to correctly classify subsequent movement in 85% of the cases as compared to 65% when only hemodynamic parameters were used as the input to the network. When both the measures were combined, the recognition rate rose to greater than 92%. When the anesthetic concentration was added as an input the network could be considerably simplified without sacrificing classification accuracy. This recognition system shows the feasibility of using the EEG signals for movement during anesthesia.
Integron Content of Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains over 12 Years in a Single Hospital in Madrid, Spain

ABSTRACT The contribution of integrons to the dissemination of extended-spectrum β-lactamases (ESBL) was analyzed on all ESBL-producing Escherichia coli isolates from 1988 to 2000 at Ramón y Cajal Hospital. We studied 133 E. coli pulsed-field gel electrophoresis types: (i) 52 ESBL-producing clinical strains (C-ESBL) (16 TEM, 9 SHV, 21 CTX-M-9, 1 CTX-M-14, and 5 CTX-M-10); (ii) 43 non-ESBL blood clinical strains (C-nESBL); and (iii) 38 non-ESBL fecal isolates from healthy volunteers (V-nESBL). Class 1 integrons were more common among C-ESBL (67%) than among C-nESBL (40%) or V-nESBL (26%) (P < 0.001) due to the high number of strains with blaCTX-M-9, which is linked to an In6-like class 1 integron. Without this bias, class 1 integron occurrence would be similar in C-ESBL and C-nESBL groups (47% versus 40%). Occurrence of class 2 integrons was similar among clinical and community isolates (13 to 18%). No isolates contained class 3 integrons. The relatively low rate of class 1 integrons within transferable elements carrying blaTEM (23%) or blaSHV (33%) and the absence of class 2 integrons in all ESBL transconjugants mirror the assembly of translocative pieces containing blaTEM or blaSHV on local available transferable elements lacking integrons. The low diversity of class 1 integrons (seven types recovered in all groups) might indicate a wide dissemination of specific genetic elements in which they are located. In our environment, the spread of genetic elements encoding ESBL has no major impact on the dispersion of integrons, nor do integrons have a major impact on the spread of ESBL, except when blaESBL genes are within an integron platform such as blaCTX-M-9.
Attentional Inhibition in Bilingual Naming Performance: Evidence from Delta-Plot Analyses

It has been argued that inhibition is a mechanism of attentional control in bilingual language performance. Evidence suggests that effects of inhibition are largest in the tail of a response time (RT) distribution in non-linguistic and monolingual performance domains. We examined this for bilingual performance by conducting delta-plot analyses of naming RTs. Dutch–English bilingual speakers named pictures using English while trying to ignore superimposed neutral Xs or Dutch distractor words that were semantically related, unrelated, or translations. The mean RTs revealed semantic, translation, and lexicality effects. The delta plots leveled off with increasing RT, more so when the mean distractor effect was smaller as compared with larger. This suggests that the influence of inhibition is largest toward the distribution tail, corresponding to what is observed in other performance domains. Moreover, the delta plots suggested that more inhibition was applied by high- than low-proficiency individuals in the unrelated than the other distractor conditions. These results support the view that inhibition is a domain-general mechanism that may be optionally engaged depending on the prevailing circumstances.
Drifting Down the Technologization of Life: Could Choreography-Based Interaction Design Support us in Engaging with the World and our Embodied Living?

The development of interactive technology is often based on the assumption of need to reduce the physical action and cognitive load of the user. However, recent conceptualizations, supported by research in various fields of science, emphasize human physical action in cognitive processes and knowledge formation. In fact, physical and closely related imaginary movement can be seen as the quintessence of humanity. Acknowledging this should imply a new approach to the design of interactive technology. In the current study, we propose a choreographic approach for shifting the focal point of interaction design to the aspects of human activity and movement within a technologized context. Hence, the proposed approach does not isolate use-related actions, which traditionally have been emphasized in interaction design, from the other activities of a person. The application of the methodological approach is divided into micro, local and macro levels, thus covering actions from minimal muscular activity of an individual to global movement-relevant issues.
Development and preliminary validation of the Opioid Abuse Risk Screener

Prescription opioid drug abuse has reached epidemic proportions. Individuals with chronic pain represent a large population at considerable risk of abusing opioids. The Opioid Abuse Risk Screener was developed as a comprehensive self-administered measure of potential risk that includes a wide range of critical elements noted in the literature to be relevant to opioid risk. The creation, refinement, and preliminary modeling of the item pool, establishment of preliminary concurrent validity, and the determination of the factor structure are presented. The initial development and validation of the Opioid Abuse Risk Screener shows promise for effective risk stratification.
Therapeutic Perspective on Tardive Syndrome with Special Reference to Deep Brain Stimulation

Tardive syndrome (TDS) is a potentially permanent and irreversible hyperkinetic movement disorder caused by exposure to dopamine receptor blocking agents. Guidelines published by the American Academy of Neurology recommend pharmacological first-line treatment for TDS with clonazepam (level B), ginkgo biloba (level B), amantadine (level C), and tetrabenazine (level C). Recently, a class II study provided level C evidence for use of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in patients with TDS. Although the precise pathogenesis of TDS remains to be elucidated, the beneficial effects of GPi-DBS in patients with TDS suggest that the disease may be a basal ganglia disorder. In addition to recent advances in understanding the pathophysiology of TDS, this article introduces the current use of DBS in the treatment of medically intractable TDS.