Miracle-dz/UniFAR-FTUs huggingface dataset:
An Exploratory Study on the Student Acceptance of the Work System Method as Part of the Systems Analysis and Design Course

The Work System Method (WSM) has been getting wider attention by the Information Systems research community recently. Its potential for improving the practicing and teaching of Systems Analysis and Design (SA&D) is one of the directions of growing research associated with it. This paper provides the results from an exploratory research on the acceptance of the work system method by students in an undergraduate SAD course at a public US university. The research questions relate to the revealing of student perceptions about the WSM training received during the course, overall student opinion of WSM, the impact of some characteristics of the WSM on success in SA&D, the physical accessibility of the WSM and whether the students would use WSM even if it was not required. The initial results are promising regarding the relevance of WSM for teaching systems analysis and its acceptance by students.
Parental Overprotection and Emotional Abuse Predict the Presence of Psychopathic Traits in Adulthood

Recent findings support an association between childhood maltreatment and the presence of elevated psychopathic traits in adulthood. Using a community sample recruited online (N = 210), we sought to (1) confirm the relationship between childhood traumas and psychopathic traits, and (2) investigate the role of parenting styles in psychopathic traits. Consistent with our predictions, we found an association between all types of childhood traumas and disinhibition. Age and gender moderated the relations between psychopathic traits and childhood maltreatments. Parental rejection and overprotection were positively correlated with the presence of psychopathic traits, while parental emotional warmth was negative correlated. Although our results converge with previous findings, the strength of the correlations observed was not as compelling as in research on undergraduate students. We discuss the numerous interpretations for our findings, and highlight the limitations of research in the field of psychopathy and childhood trauma in the general population.
Preliminary Canopy Removal Experiments in Algal Dominated Communities Low on the Shore and in the Shallow Subtidal on the Isle of Man

The algal dominated communities immediately above and below the low-water spring level on a moderately exposed Manx shore were investigated by canopy removal experiments. Fucus serratus, Laminaria digitata and L. hyperborea were removed. Competition was shown to be important in determining the zonation of L. digitata and the distribution along the wave exposure gradient of other species such as Alaria esculenta, Desmarestia aculeata and D. viridis, and L. saccharina. Many species of algal epiphytes were early colonizers of canopy removal areas suggesting that competition from canopy algae usually restricts them to an epiphytic habit. The results indicate that interactions between macrophytes are much more important than grazing in structuring these communities.
HIV/AIDS RELATED KAP AMONG HIGH-SCHOOL STUDENTS OF MUNICIPAL CORPORATION SCHOOL IN PUNE. - AN INTERVENTIONAL STUDY

Background: Adolescents form substantial risk group due to situations arising out of their curiosity, haphazard knowledge, and risk-prone behavior. Present study was planned with an objective to assess knowledge, attitude about HIV/AIDS in adolescents. Methodology: The study was conducted in a school of field practice area of Urban Health Training Center. Pre-designed, pre-tested anonymous, self administered questionnaire was filled by 9th standard students after obtaining necessary permission. A film on HIV/AIDS was shown to them. The same questionnaire was again filled by the students. Results: Sixty three percent students were aware about HIV/AIDS. TV was the main source of information. A significant decrease in knowledge about misconceptions and significant increase in knowledge occurred about various modes of transmission of disease, prevention of HIV/AIDS in post testing. Conclusion: Intervention in the form of a film even can make a significant change in knowledge and attitude of adolescents going to school.
Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Drug Targeting Drug efficacy depends on the extent of binding to a cellular target (often a protein) with adverse effects caused by excessive target binding or by off-target binding. Engagement of a target protein inside cells is influenced by the effective drug concentration and by factors that regulate the protein conformation, making it difficult to predict efficacy based on in vitro affinity studies. Martinez Molina et al. (p. 84) took advantage of the shift in protein thermal stability caused by drug binding to directly monitor target protein-drug interactions in cells. The method was used to monitor drug target engagement in cancer cells and in mouse livers and kidneys. A method to monitor drug binding to proteins in cells may help in target validation and drug optimization. The efficacy of therapeutics is dependent on a drug binding to its cognate target. Optimization of target engagement by drugs in cells is often challenging, because drug binding cannot be monitored inside cells. We have developed a method for evaluating drug binding to target proteins in cells and tissue samples. This cellular thermal shift assay (CETSA) is based on the biophysical principle of ligand-induced thermal stabilization of target proteins. Using this assay, we validated drug binding for a set of important clinical targets and monitored processes of drug transport and activation, off-target effects and drug resistance in cancer cell lines, as well as drug distribution in tissues. CETSA is likely to become a valuable tool for the validation and optimization of drug target engagement.
How men and women view ethics

business today and the benefits are numerous. But, there is also a downside to the easy data access that IS provides. There are opportunities for invasion of privacy, as well as theft of data, money, and intellectual property (such as software and product designs). Harm can also be done by altering data or modifying software. Studies have cited the monetary loss to businesses as a result of the misuse of computers and computer fraud amounts to billions of dollars per year. A recent article in Fortune magazine reported how easily the security of a business information system was breached. The article noted that many companies do not report such problems to avoid harmful publicity. Information Week surveyed security managers and IS chiefs and found that nearly half of the 1,300 respondents suffered security-related losses. Most of the research in IS ethics has concentrated on premeditated computer misuse and fraud and what preventive measures might be effective. However, the results discussed here explore situations where an employee’s behavior is not blatantly criminal. Not everyone sets out to commit a computer crime or to do harm, but the extensive systems and computer networks available today sometimes put people in situations where they must Jennifer Kreie and Timothy Paul Cronan
Regularity Extraction from Non-Adjacent Sounds

The regular behavior of sound sources helps us to make sense of the auditory environment. Regular patterns may, for instance, convey information on the identity of a sound source (such as the acoustic signature of a train moving on the rails). Yet typically, this signature overlaps in time with signals emitted from other sound sources. It is generally assumed that auditory regularity extraction cannot operate upon this mixture of signals because it only finds regularities between adjacent sounds. In this view, the auditory environment would be grouped into separate entities by means of readily available acoustic cues such as separation in frequency and location. Regularity extraction processes would then operate upon the resulting groups. Our new experimental evidence challenges this view. We presented two interleaved sound sequences which overlapped in frequency range and shared all acoustic parameters. The sequences only differed in their underlying regular patterns. We inserted deviants into one of the sequences to probe whether the regularity was extracted. In the first experiment, we found that these deviants elicited the mismatch negativity (MMN) component. Thus the auditory system was able to find the regularity between the non-adjacent sounds. Regularity extraction was not influenced by sequence cohesiveness as manipulated by the relative duration of tones and silent inter-tone-intervals. In the second experiment, we showed that a regularity connecting non-adjacent sounds was discovered only when the intervening sequence also contained a regular pattern, but not when the intervening sounds were randomly varying. This suggests that separate regular patterns are available to the auditory system as a cue for identifying signals coming from distinct sound sources. Thus auditory regularity extraction is not necessarily confined to a processing stage after initial sound grouping, but may precede grouping when other acoustic cues are unavailable.
The magnetic field in the photospheric and circumstellar components of Herbig Ae stars

Aims.We investigate the photospheric and circumstellar (CS) magnetic field components separately in seven Herbig Ae stars. Methods: The study is based on low-resolution (REœ 2000 and 4000) spectropolarimetric data collected from 2003 to 2005 at the Very Large Telescope (ESO, Chile) with the multi-mode instrument FORS1. Results: We show that the spectropolarimetric results strongly depend on the level of CS contribution to the stellar spectra. We have improved the determination accuracy of magnetic fields up to the 7sigma level in the two Herbig Ae stars HD 139614 and HD 144432, observed in 2005 when these objects were at a low level state in their CS activity. We have established that at a higher level state of CS activity the polarisation signatures are mainly related to the CS matter. The presence of CS polarisation signatures formed in the stellar wind supports the assumption that the magnetic centrifuge is one of the main mechanisms of wind acceleration. Conclusions: . We conclude that the most effective way to investigate the magnetism of Herbig Ae stars is to monitor their spectropolarimetric behaviour at different stages of CS activity. Obviously, higher-resolution spectropolarimetric observations would extend the sample of spectral lines which can be used to measure magnetic fields at different levels in the stellar atmosphere and CS envelope. These observations will give a more complete insight into the magnetic topology in Herbig Ae stars. Based on observations collected at the European Southern Observatory, Paranal, Chile (ESO programme Nos. 072.D-0377, 073.D-0464, 074.C-0463, and 075.D-0507).
Classifying learnable geometric concepts with the Vapnik-Chervonenkis dimension

We extend Valiant's learnability model to learning classes of concepts defined by regions in Euclidean space E". Our methods lead to a unified treatment of some of Valiant's results, along with previous results of Pearl and Devroye and Wagner on distribution-free convergence of certain pattern recognition algorithms. We show that the essential condition for distribution-free learnability is finiteness of the Vapnik-Chervonenkis dimension, a simple combinatorial parameter of the class of concepts to be learned. Using this parameter, we analyze the complexity and closure properties of learnable classes. Authors A. Blumer and D. Haussler gratefully acknowledge the support of NSF grant IST-8317918, author A. Ehrenfeucht the support of NSF grant MCS-8305245, and author M. Warmuth the support of the Faculty Research Committee of the University of California at Santa Cruz. Part of this work was done while A. Blumer was visiting the University of California at Santa Cruz and M. Warmuth the Univer-
Optimal space–time precoding of artificial sensory feedback through mutichannel microstimulation in bi-directional brain–machine interfaces

Brain–machine interfaces (BMIs) aim to restore lost sensorimotor and cognitive function in subjects with severe neurological deficits. In particular, lost somatosensory function may be restored by artificially evoking patterns of neural activity through microstimulation to induce perception of tactile and proprioceptive feedback to the brain about the state of the limb. Despite an early proof of concept that subjects could learn to discriminate a limited vocabulary of intracortical microstimulation (ICMS) patterns that instruct the subject about the state of the limb, the dynamics of a moving limb are unlikely to be perceived by an arbitrarily-selected, discrete set of static microstimulation patterns, raising questions about the generalization and the scalability of this approach. In this work, we propose a microstimulation protocol intended to activate optimally the ascending somatosensory pathway. The optimization is achieved through a space–time precoder that maximizes the mutual information between the sensory feedback indicating the limb state and the cortical neural response evoked by thalamic microstimulation. Using a simplified multi-input multi-output model of the thalamocortical pathway, we show that this optimal precoder can deliver information more efficiently in the presence of noise compared to suboptimal precoders that do not account for the afferent pathway structure and/or cortical states. These results are expected to enhance the way microstimulation is used to induce somatosensory perception during sensorimotor control of artificial devices or paralyzed limbs.
A Kramers–Kronig-based quality factor for shear wave propagation in soft tissue

Shear wave propagation techniques have been introduced for measuring the viscoelastic material properties of tissue, but assessing the accuracy of these measurements is difficult for in vivo measurements in tissue. We propose using the Kramers–Kronig relationships to assess the consistency and quality of the measurements of shear wave attenuation and phase velocity. In ex vivo skeletal muscle we measured the wave attenuation at different frequencies, and then applied finite bandwidth Kramers–Kronig equations to predict the phase velocities. We compared these predictions with the measured phase velocities and assessed the mean square error (MSE) as a quality factor. An algorithm was derived for computing a quality factor using the Kramers–Kronig relationships.
Feedback in the Local Lyman-break Galaxy Analog Haro 11 as Probed by Far-Ultraviolet and X-Ray Observations

We have reanalyzed FUSE data and obtained new Chandra observations of Haro 11, a local (DL = 88 Mpc) UV luminous galaxy. Haro 11 has a far-UV luminosity (1010.3 L☉), UV surface brightness (109.4 L☉ kpc-2), star formation rate (SFR), and metallicity similar to those observed in Lyman-break galaxies (LBGs). We show that Haro 11 has extended soft thermal (kT ~ 0.68 keV) X-ray emission of a luminosity and size which scales with the physical properties (e.g., SFR, stellar mass) of the host galaxy. An enhanced α/Fe ratio of ~4 relative to solar abundance suggests significant supernova enrichment. These results are consistent with the X-ray emission being produced in a shock between a supernova-driven outflow and the ambient material. The far-ultraviolet (FUV) spectra show strong absorption lines similar to those observed in LBG spectra. A blueshifted absorption component is identified as a wind outflowing at ~200-280 km s-1. O VI λλ1032,1038 emission, the dominant cooling mechanism for coronal gas at T ~ 105.5 K, is also observed. If associated with the outflow, the luminosity of the O VI emission suggests that ≲20% of the total mechanical energy from the supernovae and solar winds is being radiated away. This implies that radiative cooling through O VI is not significantly inhibiting the growth of the outflowing gas. In contradiction to the findings of Bergvall and coworkers, we find no convincing evidence of Lyman continuum leakage in Haro 11. We conclude that the wind has not created a "tunnel" allowing the escape of a significant fraction of Lyman continuum photons, and place a limit on the escape fraction of fesc ≲ 2%. Overall, both Haro 11 and a previously observed LBG analog, VV 114, provide invaluable insight into the X-ray and FUV properties of high-redshift LBGs.
Review on the research methods of the barrier and explosion-proof properties of porous materials

Barrier and explosion proof material can quickly transfer heat and block flame propagation, consequently prevent explosion accident. It is the essential safety technology to solve the problem of explosion or “secondary explosion” during the storage and transportation of flammable and explosive dangerous chemicals in liquid or gaseous state. Since the 1960s, the research at home and abroad on the barrier and explosion proof technology has been carried out mainly for the storage and transportation safety of fuel oil. It has been widely used in automobile fuel tank, fuel carrier, gas station, oil pipeline and aircraft fuel tank. In this paper, the research methods of barrier and explosion protection are reviewed, and the development of this technology in the future is prospected.Barrier and explosion proof material can quickly transfer heat and block flame propagation, consequently prevent explosion accident. It is the essential safety technology to solve the problem of explosion or “secondary explosion” during the storage and transportation of flammable and explosive dangerous chemicals in liquid or gaseous state. Since the 1960s, the research at home and abroad on the barrier and explosion proof technology has been carried out mainly for the storage and transportation safety of fuel oil. It has been widely used in automobile fuel tank, fuel carrier, gas station, oil pipeline and aircraft fuel tank. In this paper, the research methods of barrier and explosion protection are reviewed, and the development of this technology in the future is prospected.
Characterization of the Viral O-Glycopeptidome: a Novel Tool of Relevance for Vaccine Design and Serodiagnosis

ABSTRACT Viral envelope proteins mediate interactions with host cells, leading to internalization and intracellular propagation. Envelope proteins are glycosylated and are known to serve important functions in masking host immunity to viral glycoproteins. However, the viral infectious cycle in cells may also lead to aberrant glycosylation that may elicit immunity. Our knowledge of immunity to aberrant viral glycans and glycoproteins is limited, potentially due to technical limitations in identifying immunogenic glycans and glycopeptide epitopes. This work describes three different complementary methods for high-throughput screening and identification of potential immunodominant O-glycopeptide epitopes on viral envelope glycoproteins: (i) on-chip enzymatic glycosylation of scan peptides, (ii) chemical glycopeptide microarray synthesis, and (iii) a one-bead-one-compound random glycopeptide library. We used herpes simplex virus type 2 (HSV-2) as a model system and identified a simple O-glycopeptide pan-epitope, 501PPA(GalNAc)TAPG507, on the mature gG-2 glycoprotein that was broadly recognized by IgG antibodies in HSV-2-infected individuals but not in HSV-1-infected or noninfected individuals. Serum reactivity to the extended sialyl-T glycoform was tolerated, suggesting that self glycans can participate in immune responses. The methods presented provide new insight into viral immunity and new targets for immunodiagnostic and therapeutic measures.
Introduction to Conformal Field Theory

In these lectures, we provide a introduction to Conformal Field Theory with applications to Condensed Matter Physics in mind. More directly, these provide the background information one would need for the lectures given by P. Durganandini in this Workshop. Hence these are not comprehensive. The interested reader is directed to some of the more elaborate reviews on the subject[3, 4].
Social ties and their relevance to churn in mobile telecom networks

Social Network Analysis has emerged as a key paradigm in modern sociology, technology, and information sciences. The paradigm stems from the view that the attributes of an individual in a network are less important than their ties (relationships) with other individuals in the network. Exploring the nature and strength of these ties can help understand the structure and dynamics of social networks and explain real-world phenomena, ranging from organizational efficiency to the spread of information and disease. In this paper, we examine the communication patterns of millions of mobile phone users, allowing us to study the underlying social network in a large-scale communication network. Our primary goal is to address the role of social ties in the formation and growth of groups, or communities, in a mobile network. In particular, we study the 'evolution of churners in an operator's network spanning over a period of four months. Our analysis explores the propensity of a subscriber to churn out of a service provider's network depending on the number of ties (friends) that have already churned. Based on our findings, we propose a spreading activation-based technique that predicts potential churners by examining the current set of churners and their underlying social network. The efficiency of the prediction is expressed as a lift curve, which indicates the fraction of all churners that can be caught when a certain fraction of subscribers were contacted.
The biomechanics of below-knee prostheses in normal, level, bipedal walking.

H U M A N locomotion involves the transformation of a series of controlled and coordinated angular motions occurring simultaneously at the various joints of the lower extremity into a smooth path of motion for the center of gravity of the body as a whole. Though largely taken for granted, it is an extremely complicated process, the complexity becoming evident when one considers that the path of motion is influenced by six major factors: knee-ankle interaction, knee flexion, hip flexion, pelvic rotation about a vertical axis, lateral tilting of the pelvis, and lateral displacement of the pelvis. A thorough study of walking in the orthograde attitude would therefore include not only the influence of each of these factors on the total displacement pattern but also a complete analysis of the action of major muscle groups of the lower extremity. The present discussion is limited to a consideration of the hip, knee, and ankle joints and of their interaction during level walking—first in the normal person and then in the case of the below-knee amputee wearing the patellar-tendon-bearing prosthesis with and without additional impedimenta in the form of thigh corset and sidebars.
A New Look at Relationships between Size at Maturity and Asymptotic Size

Comparative studies have revealed positive correlations between size at maturity and asymptotic size in several taxa with asymptotic growth after maturity. Using a simple growth model, we show that positive correlations between size at maturity and asymptotic size are predicted for different individuals in the same species if growth costs of reproduction are inversely related to size at maturity. Several processes might lead to higher growth costs of reproduction for smaller individuals; these include effects of body size on competition for resources required for breeding, on the space available within the body cavity for food processing in gravid individuals, and on the costs of transporting eggs or young in relation to the total energy budget. We confirm several key elements of the growth model using data from female Iguana iguana lizards, including the novel assumption that instantaneous growth rates of adults of the same length will be positively related to their length at maturity. These analyses suggest a simple and possibly general explanation for positive correlations between size at maturity and asymptotic size within—and perhaps also among—species that continue to grow after maturity.