Miracle-dz/UniFAR-FTUs huggingface dataset:
Perinatal exposure to methoxychlor enhances adult cognitive responses and hippocampal neurogenesis in mice

During perinatal life, sex steroids, such as estradiol, have marked effects on the development and function of the nervous system. Environmental estrogens or xenoestrogens are man-made chemicals, which animal and human population encounter in the environment and which are able to disrupt the functioning of the endocrine system. Scientific interest in the effects of exposure to xenoestrogens has focused more on fertility and reproductive behaviors, while the effects on cognitive behaviors have received less attention. Therefore, the present study explored whether the organochlorine insecticide Methoxychlor (MXC), with known xenoestrogens properties, administered during the perinatal period (from gestational day 11 to postnatal day 8) to pregnant-lactating females, at an environmentally relevant dose (20 µg/kg (body weight)/day), would also affect learning and memory functions depending on the hippocampus of male and female offspring mice in adulthood. When tested in adulthood, MXC perinatal exposure led to an increase in anxiety-like behavior and in short-term spatial working memory in both sexes. Emotional learning was also assessed using a contextual fear paradigm and MXC treated male and female mice showed an enhanced freezing behavior compared to controls. These results were correlated with an increased survival of adult generated cells in the adult hippocampus. In conclusion, our results show that perinatal exposure to an environmentally relevant dose of MXC has an organizational effect on hippocampus-dependent memory and emotional behaviors.
Zeros of the Jimbo, Miwa, Ueno tau function

We introduce a family of local deformations for meromorphic connections on P1 in the neighborhood of a higher rank (simple) singularity. Following the scheme in Malgrange [Mathematique et Physique, Progress in Mathematics (Birkhauser, Boston, 1983), Vol. 37, pp. 381–400, ibid., pp. 401–426; ibid., pp. 427–438] we use these local models to prove that the zeros of the tau function, introduced by Jimbo, Miwa, and Ueno in their pioneering work on “Birkhoff” deformations at irregular singular points [Physica D 2, 306–352; 2, 407–448 (1981); 4, 26–46 (1983); Publ. RIMS Kyoto Univ. 17-2, 703–721 (1981)], occur at precisely those points in the deformation space at which a certain Birkhoff–Riemann–Hilbert problem fails to have a solution.
The Impact of a Three-Tier Formulary on Demand Response for Prescription Drugs

A large number of health plans and employers have adopted three-tier prescription drug formularies in an effort to control rising prescription drug costs. We assessed the behavioral response to three-tier adoption by estimating econometric models of the probability of selecting drugs assigned to the third tier with the highest co-payment requirement and changes in expected out-of-pocket (OOP) spending. We concluded that implementation of the three-tier formulary resulted in some shifting of costs from the plan to enrollees and some bargaining power gained for the payer, with plan savings from manufacturer rebates a likely result.
UvA-DARE ( Digital Academic Repository ) New theoretical yields of intermediate mass stars

We present theoretical yields of H, He, C, C, N, and O for stars with initial masses between 0.8 and 8 M and initial metallicities Z = 0.001, 0.004, 0.008, 0.02, and 0.04. We use the evolutionary tracks of the Geneva group up to the early asymptotic giant branch (AGB) in combination with a synthetic thermal-pulsing AGB evolution model to follow in detail the chemical evolution and mass loss up to the end of the AGB including the first, second, and third dredge-up phases. Most of the relations used are metallicity dependent to make a realistic comparison with stars of different initial abundances. The effect of Hot Bottom Burning (HBB) is included in an approximate way. The free parameters in our calculations are the mass loss scaling parameter ηAGB for stars on the AGB (using a Reimers law), the minimum core mass for dredge-up M c , and the third dredge-up efficiency λ. As derived from previous extensive modeling, ηAGB = 4, M min c = 0.58 M , and λ = 0.75 including HBB are in best agreement with observations of AGB stars both in the Galactic disk and Magellanic Clouds. The influence of specific model assumptions and adopted parameter values on the resulting AGB yields is examined and compared with earlier theoretical work. We compare the abundances predicted during the final stages of the AGB with those observed in planetary nebulae in the Galactic disk and show that the model with the aforementioned parameters is in good agreement with the observations. The metallicity dependent yields of intermediate mass stars presented in this paper are well suited for use in galactic chemical evolution models.
Lone wolves reciprocate less deviance: a moral identity model of abusive supervision*

Abstract Although previous studies provide diverse perspectives on the influences of abusive supervision, the moral perspective receives little attention in the literature. We rely on social cognitive theory to present a moral identity model of abusive supervision that accounts for the influences of perceiving abusive supervision on organizational and interpersonal deviance. In particular, we propose that employee moral identity mediates the positive relations between abusive supervision, as perceived by followers, and their subsequent organizational and interpersonal deviance. We also test the extent to which lone wolf tendencies alleviate the main negative impact of abusive supervision on moral identity and the indirect effect of abusive supervision on organizational and interpersonal deviance through moral identity. More specifically, when the level of lone wolf tendencies is high, the relationship between abusive supervision and moral identity, and the magnitude of the moral identity mediating mechanism will be weaker. Using multi-wave, multiple-source data collected in China, our findings support most of our hypotheses and offer insightful theoretical directions for mistreatment, morality, and disposition research. Our moderated mediation model serves as a springboard for future research to understand the social cognitive processes that link abusive supervision and deviant behavior from the moral perspective.
The Impact of Cooperative Learning on Female Medical Students’ Happiness and Social Support

Cooperative learning has appeared as a new approach to teaching. This approach is utilized for small heterogeneous groups of students who cooperate to achieve a common goal. This study aimed at investigating the impact of cooperative learning on female medical students’ happiness and social support. To this end, 72 female students of medicine at Shiraz Medical School were selected using cluster sampling and divided into experimental and control groups. The students were administered social support and happiness questionnaires as a pre-test. The same questionnaires were administered to them at the end of the term as a post-test. The students in the experimental group were taught to use cooperative learning strategies and the students in the control group followed the traditional approach. Data were analyzed using SPSS. The statistical procedures used for analyzing the data were mean, standard deviation, and multivariate analysis of covariance. The findings of the study indicated that cooperative learning had a significant impact on the level of happiness and social support of students compared to the conventional approach.
The role of inter-professional collaboration in developing inclusive education: experiences of teachers and occupational therapists in Slovenia

ABSTRACT This was the first qualitative study of the inclusion of children with special needs into regular schools in Slovenia that focused on inter-professional collaboration and its contributions to the inclusion process. Focus groups and individual interviews were conducted with primary school teachers (N = 36) and occupational therapists (N = 9) to explore their personal experiences. Data were analysed using qualitative content analysis (Strauss, A., and J. Corbin. 1998. Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory. Thousand Oaks, CA: Sage). Two categories pertaining to inter-professional collaboration emerged from the analysis. They described different barriers and strategies that either inhibited or facilitated the cooperation process. The experiences of teachers and occupational therapists differed; however, both professional groups expressed frustration with organisational and systemic factors that often prevented better exchange of knowledge and information. Due to the organisation of work and financial issues, occupational therapists had limited access to the school environment; therefore, they generally showed more eagerness to increase the level of collaboration and their presence at the school. The study also pointed out how the roles of certain professionals are not recognised, suggesting the need for more promotional work. If inclusion in Slovenia is to be fully implemented, collaboration between different professionals working with children with special needs must strengthen. This will require some significant organisational, cultural and also personal transformations.
Gain Field Encoding of the Kinematics of Both Arms in the Internal Model Enables Flexible Bimanual Action

Bimanual action requires the neural controller (internal model) for each arm to predictively compensate for mechanical interactions resulting from movement of both that arm and its counterpart on the opposite side of the body. Here, we demonstrate that the brain may accomplish this by constructing the internal model with primitives multiplicatively encoding information from the kinematics of both arms. We had human participants adapt to a novel force field imposed on one arm while both arms were moving in particular directions and examined the generalization pattern of motor learning when changing the movement directions of both arms. The generalization pattern was consistent with the pattern predicted from the multiplicative encoding scheme. As proposed by previous theoretical studies, the strength of multiplicative encoding was manifested in the observation that participants could adapt reaching movements to complicated force fields depending nonlinearly on the movement directions of both arms. These results indicate that multiplicative neuronal influence of the kinematics of the opposing arm on the internal models enables the brain to control bimanual movement by providing great flexible ability to handle arbitrary dynamical environments resulting from the interactions of both arms.
Grasp Movement Decoding from Premotor and Parietal Cortex

Despite recent advances in harnessing cortical motor-related activity to control computer cursors and robotic devices, the ability to decode and execute different grasping patterns remains a major obstacle. Here we demonstrate a simple Bayesian decoder for real-time classification of grip type and wrist orientation in macaque monkeys that uses higher-order planning signals from anterior intraparietal cortex (AIP) and ventral premotor cortex (area F5). Real-time decoding was based on multiunit signals, which had similar tuning properties to cells in previous single-unit recording studies. Maximum decoding accuracy for two grasp types (power and precision grip) and five wrist orientations was 63% (chance level, 10%). Analysis of decoder performance showed that grip type decoding was highly accurate (90.6%), with most errors occurring during orientation classification. In a subsequent off-line analysis, we found small but significant performance improvements (mean, 6.25 percentage points) when using an optimized spike-sorting method (superparamagnetic clustering). Furthermore, we observed significant differences in the contributions of F5 and AIP for grasp decoding, with F5 being better suited for classification of the grip type and AIP contributing more toward decoding of object orientation. However, optimum decoding performance was maximal when using neural activity simultaneously from both areas. Overall, these results highlight quantitative differences in the functional representation of grasp movements in AIP and F5 and represent a first step toward using these signals for developing functional neural interfaces for hand grasping.
Graph Search Techniques for Mobile Robot Path Planning

In a number of applications, the problem of determining the optimum path occurs. This applications range from finding the fastest path in a network, to determining the safest path for mobile vehicle, wandering on the surface of Mars. In this context, we shall limit our scope to the case of finding paths in Euclidean two-dimensional space. Moreover we shall limit the case study to movements along a surface that can be projected onto a directed graph. To be specific, we shall look at the case of finding the optimum path for a mobile robot moving along a flat surface, the robot’s configurations in the configuration space being the graph’s nodes while the graph’s arcs represent the cost of moving from one configuration to another. Researchers have tried to come with new and better navigation technologies in the last years. With the development of path finding, several new classical routing algorithms have been introduced to generate better routing solution. For example the Dijkstra algorithm is the most famous one, which evaluates the moving cost from one node to any other node and sets the shortest moving cost as the connecting cost of two nodes (Eklund et al., 1996). Around the same period of time, Best-First-Search algorithm is also introduced in the researchers’ community. A little different from the Dijkstra algorithm, Best-First-Search algorithm has a different approach because it estimates the distance from current position to goal position, and it chooses the step that is closer to the goal position (LaValle, 2006). The difficulty was growing with the new path finding situations so the old path finding algorithm had to be improved to meet the new introduced requirements. A new path finding algorithm was introduced and it was named the A* algorithm. The A* algorithm tries to combine the advantages offered by Dijkstra algorithm and Best-FirstSearch algorithm. This paper presents tests performed with various implementations of graph search algorithms (A*, D*, focused D*) as path planners for a mobile robot, focused on strong points and drawbacks of each implementation. 8
Faktor-faktor yang mempengaruhi kecemasan ibu hamil trimester III

Abstract: The purpose of this study was to determine the factors that influence on anxiety of pregnancy third trimester. This research is a descriptive cross-sectional design. The sampling technique used is consecutive sampling with the total sample 61 respondents. The analysis used is independent t test. The results showed the factors that influence on anxiety of pregnancy third trimester is the support of husband with a p value of 0,048 (p 0,05. Conclusions factors that influence anxiety third trimester pregnant women isthe support of husband.
Does team orientation matter? Linking work engagement and relational psychological contract with performance

Purpose The cultural transformation introduces team orientation as a powerful tool to reconfigure the human capital to become more productive. The purpose of this paper is to try to uncover two folds: first is to check the direct effects of employees’ work engagement and rational psychological contract on contextual performance and job satisfaction and second is to investigate the moderating effect of team orientation in-between above-stated relationships. Design/methodology/approach The self-administrated questionnaires and simple random sampling are used to collect data from 380 employees of banking and insurance sector. Findings The findings reveal that work engagement and relational psychological contract have positive relationships with employees’ contextual performance and job satisfaction. Furthermore, the presence of team orientation has strengthened effect on direct existing relationships. Practical implications This study adds the body of knowledge by providing insights into team orientation in different avenues. For practice side, it is important to discourse the work engagement of employee and their relational psychological contract to enhance the contextual performance. Moreover, high work engagement leads to high commitment level and ultimately increases the level of job satisfaction. Originality/value The contemporary research is lacking with respect to the empirical investigation of team orientation, more particularly, in relationship to human psychology factors. This unique model is addressing the real time issue by providing insights to relational psychological contract, employees work engagement, contextual performance and job satisfaction.
EXPORTS AND ECONOMIC GROWTH : AN EMPIRICAL INVESTIGATION OF E . U , U . S . A AND JAPAN USING CAUSALITY TESTS

This paper investigates the relationship between exports and economic growth in the three of the largest exporting countries in the world, such as European Union, United States of America and Japan. For this purpose we have used Granger causality analysis based on error correction model. The results of this paper suggested that exports have a causal effect on the development process for the countries of European Union, USA, while there is no causal relationship between the examined variables for Japan. keywords: exports, economic growth, cointegration, Granger causality
A clinicopathologic study of patients with hemorrhagic myocardial infarction treated with selective coronary thrombolysis with urokinase.

Hemorrhagic acute myocardial infarction (AMI) was studied after selective intracoronary thrombolysis (SICT) in 30 patients undergoing autopsy. Urokinase, 240,000 to 1,200,000 U, was selectively injected into the infarct-related coronary artery at 2 to 9 hr (4 +/- 2 hr) after the onset of AMI. The infarct-related coronary artery showed complete occlusion in 21, 99% stenosis in eight, and 90% stenosis in one patient before SICT. After SICT, complete occlusion was seen in only five, 99% stenosis in 22, and 90% stenosis in three patients. Twenty-eight patients had transmural infarction and the other two had subendocardial infarction. Macroscopically and microscopically, the degree of hemorrhage was classified as no, slight, moderate, or marked bleeding and the hemorrhagic infarction was defined as moderate or marked diffuse bleeding in the infarct area. According to the interval from SICT to death, patients were also classified into stage I (early acute stage, 1 to 4 hr after SICT and 4 to 13 hr after the onset of AMI; n = 7), stage II (late acute stage, 9 hr to 11 days after SICT and 15 hr to 11 days after the onset of AMI; n = 18), or stage III (old infarction stage, over 17 days after AMI and SICT; n = 5). There were no significant differences with respect to the frequency of recanalization, the time from the onset of AMI to SICT, the dose of urokinase, or other clinical parameters among patients at the three stages. Only the hearts of patients in stage II showed hemorrhagic infarction, and it was found in 15 of 18 of these hearts. (ABSTRACT TRUNCATED AT 250 WORDS)
Incremental Clone Detection

Finding, understanding and managing software clones - passages of duplicated source code - is of large interest in research and practice. There is an abundance of techniques to detect clones. However, all these techniques are limited to a single revision of a program. When the code changes, the analysis must be run again from scratch even though only small parts may have changed. In this paper, we present an incremental clone detection algorithm, which detects clones based on the results of the previous revision's analysis. Moreover, it creates a mapping between clones of one revision to the next, supplying information about the addition and deletion of clones. Our empirical results demonstrate that the incremental technique requires considerably less time than a non-incremental approach if the changes do not exceed a certain fraction of the source code. An incremental analysis is useful for on-the-fly detection and evolutionary clone analysis. On-the-fly detection may be integrated in an IDE and allows to re-run clone detection immediately when a programmer saves his changes or even while he/she is typing. In evolutionary clone analysis, many revisions of a system need to be analyzed in order to understand how clones evolve.
Spatial Practices and the Institutionalization of Water Sanitation Services in Southern Metropolises: The case of Jakarta and its Kampung Kojan

This article examines the spatial practices and forms of institutionalization in the water and water sanitation sector in Jakarta, capital of Indonesia, and especially in Kampung Kojan in the Kalideres subdistrict of Jakarta. To this end, it develops a three-layered analytical framework viewing the city as a multi-scalar socio-ecological system in which different forms of human-water relations and their institutionalization are found. Particular attention is given to informality in this system and how it interacts with 'regular' state and corporate market sector practices. Within these interactive dynamics, informality is not only understood as a survival strategy but also as a creative practice connecting various social-ecological opportunities, traditional and contemporary technologies and modes of institutionalization to each other. Ongoing institutionalization processes in the formal and informal economy, as well as between them, are analysed. Opportunities to integrate and regularize the diverse water sanitation services into community-led closed water-wastewater cycles capable of ensuring public health and sustaining a bio-hydrological balance at the local level are explored. [ABSTRACT FROM AUTHOR]
Financial Advice and Stock Market Participation

We introduce professional financial advice in households’ choice to hold risky financial assets. Consistent with the predictions from a formal model, we present evidence that households’ trust in financial advice only matters when their perceived own financial capability is low. Instead, for households with higher financial capability, only the perception of legal protection in financial markets matters for stock market participation. Our empirical analysis highlights economically significant differences in households’ perception of their rights as consumers of financial services, even when their objective circumstances should not be much different.
Exploiting Properties of Legislative Texts to Improve Classification Accuracy

Organizing legislative texts into a hierarchy of legal topics enhances the access to legislation. Manually placing every part of new legislative texts in the correct place of the hierarchy, however, is expensive and slow, and therefore naturally calls for automation. In this paper, we assess the ability of machine learning methods to develop a model that automatically classifies legislative texts in a legal topic hierarchy. It is investigated whether such methods can generalize across different codes. In the classification process, the specific properties of legislative documents are exploited. Both the hierarchical structure of legal codes and references within the legal document collection are taken into account. We argue for a closer cooperation between legal and machine learning experts as the main direction of future work.