Miracle-dz/UniFAR-FTUs huggingface dataset:
The Anatomy of Auditory Word Processing: Individual Variability

This study used functional magnetic resonance imaging (fMRI) to investigate the neural substrate underlying the processing of single words, comparing activation patterns across subjects and within individuals. In a word repetition task, subjects repeated single words aloud with instructions not to move their jaws. In a control condition involving reverse speech, subjects heard a digitally reversed speech token and said aloud the word "crime. " The averaged fMRI results showed activation in the left posterior temporal and inferior frontal regions and in the supplementary motor area, similar to previous PET studies. However, the individual subject data revealed variability in the location of the temporal and frontal activation. Although these results support previous imaging studies, demonstrating an averaged localization of auditory word processing in the posterior superior temporal gyrus (STG), they are more consistent with traditional neuropsychological data, which suggest both a typical posterior STG localization and substantial individual variability. By using careful head restraint and movement analysis and correction methods, the present study further demonstrates the feasibility of using overt articulation in fMRI experiments.
By Phrases in Passives and Nominals

A longstanding claim in the literature holds that by phrases are special in the passive, receiving certain external argument roles that by phrases in nominals cannot, such as the role of experiencer. This paper challenges this long-standing claim and shows that by phrases are not special in the passive: they can receive all of the θ-roles that they can in verbal passives. They are banned from certain nominals for the same reason they are banned from certain VP types like unaccusatives and sporadic advancements: by phrases require the syntactic and semantic presence of an external argument. By phrases can receive a uniform analysis, whether they occur with verbs or in nominals. The analysis proposed here involves syntactic word formation, with syntactic heads effecting passivization and nominalization. It also relies on syntactic selection for selectional features and proposes a theory of such features. The conception of grammar that emerges is one without lexical rules, where passivization and nominalization take place in the syntax.
Perceived Parental Behaviour of Juvenile Delinquent Boys in Prison

In order to investigate associations between parenting and delinquent behaviour in an Ethiopian context, we studied both a target group of adolescent boys (aged 13–19 years) in prison (n = 86) and a control group (n = 93). The boys completed questionnaires on perceived parenting practices and their own prosocial and problem behaviours. The results showed that boys in the prison group reported significantly less positive parenting, monitoring, rules, material rewarding and autonomy than the boys in the control group, but more harsh punishment, ignoring of unwanted behaviour and psychological control. Boys in prison also reported significantly more emotional and conduct problems. Further, results indicated that parenting dimensions (less support and more negative control) increased the odds of being in prison above family characteristics (lower educational status of the adolescent and mother, living in a family with divorced parents or in a single parent family).
Aberrant methylation of PSD disturbs Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis in ulcerative colitis-associated carcinogenesis

We previously reported that the Pleckstrin and Sec7 domain-containing (PSD) gene is preferentially methylated in patients with ulcerative colitis (UC) who developed colorectal cancer (CRC), and is implicated in UC-associated carcinogenesis through its inhibition of apoptosis. This study aimed to determine the potential effect of PSD methylation on its downstream molecule, Ras-related C3 botulinum toxin substrate 1 (Rac1), which governs neutrophil chemotaxis and apoptosis signaling. PSD was knocked down in a normal human fibroblast cell line (HNDF) and a neutrophil-like cell line (HL-60). Both NHDF and HL-60 cells exhibited numerous filamentous-actin (F-actin) rich membrane extensions, resulting in the activation of Rac1; this activation was hampered by PSD silencing. Lipopolysaccharide, a reactive oxygen species (ROS) inducer, stimulated NHDF cells to release ROS and activated caspase-3/7 in the presence of neutrophils, which was inhibited by PSD knockdown. Migration assays demonstrated that chemotaxis of HL-60 cells was affected by PSD silencing in NHDF cells. Tissue sections from 6 UC patients with CRC and 15 UC patients without CRC were examined. To verify Rac1-mediated chemotaxis in tissue sections, we evaluated the grade of neutrophil infiltration by histological assessment and assessed F-actin and PSD expression by immunohistochemistry. Neutrophil infiltration, F-actin and PSD expression were significantly decreased in specimens from UC patients with PSD methylation compared with those without. Decreased levels of F-actin expression were observed in colorectal mucosa, as well as in infiltrating cells with PSD methylation. PSD expression was preferentially inhibited in colorectal mucosa by PSD methylation, whereas PSD expression was rarely observed in infiltrating cells, regardless of PSD methylation status. These data indicate that aberrant methylation of PSD occurs in UC-associated colorectal mucosa, enabling circumvention of Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis, and thus plays a pivotal role in the mechanisms underlying UC-associated carcinogenesis.
S-CD : SURFACE COLLISION DETECTION TOOLKIT FOR VIRTUAL PROTOTYPING

This paper presents an efficient collision detection algorithm designed to support assembly and maintenance simulation of complex assemblies. This approach exploits the surface knowledge, available from CAD models, to determine intersecting surfaces. It proposes a novel combination of Overlapping Axis-Aligned Bounding Box (OAABB) and R-tree structures to gain considerable performance improvements. This paper also shows an efficient traversal algorithm based on the R-tree structure of Axis-Aligned Bounding Boxes to determine intersecting objects and intersecting surfaces between three-dimensional components, for supporting the recognition of constraints in assembly and disassembly operations in virtual prototyping environments. The implementation of the proposed collision detection algorithm, known as S-CD (Surface Collision Detection) toolkit, performs well against moderately complex industrial case studies. Current experimental results show that S-CD is effective in determining intersecting surfaces at interactive rates with moderately complex real case studies.
Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1

The histiocytoses are rare tumors characterized by the primary accumulation and tissue infiltration of histiocytes and dendritic cells. Identification of the activating BRAFV600E mutation in Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) cases provided the basis for the treatment with BRAF and/or MEK inhibitors, but additional treatment options are needed. Twenty-four cases of neoplastic histiocytic diseases [11 extrapulmonary LCH, 4 ECD, 4 extranodal Rosai-Dorfman disease (RDD), 3 follicular dendritic cell sarcoma (FDCS), 1 histiocytic sarcoma (HS) and 1 blastic plasmacytoid dendritic cell neoplasm (BPDCN)] were analyzed using immunohistochemical and mutational analysis in search of biomarkers for targeted therapy. BRAF V600E mutations were detected in 4/11 LCH and 4/4 ECD cases. A pathogenic PTEN gene mutation and loss of PTEN protein expression were identified in the case of HS. Increased expression of PD-L1 (≥2+/≥5%) was seen in 3/4 ECD, 7/8 LCH, 3/3 FDCS and 1/1 HS, with overall 81% concordance between 2 antibodies used in the study (SP142 vs. MAB1561 clone). These results show for the first time significant expression of the PD-L1 immune checkpoint protein in these disorders, which may provide rationale for addition of immune check-point inhibitors in treatment of disseminated and/or refractory histiocytoses.
Brain Activity during Mental Imagery of Gait Versus Gait-Like Plantar Stimulation: A Novel Combined Functional MRI Paradigm to Better Understand Cerebral Gait Control

Human locomotion is a complex sensorimotor behavior whose central control remains difficult to explore using neuroimaging method due to technical constraints, notably the impossibility to walk with a scanner on the head and/or to walk for real inside current scanners. The aim of this functional Magnetic Resonance Imaging (fMRI) study was to analyze interactions between two paradigms to investigate the brain gait control network: (1) mental imagery of gait, and (2) passive mechanical stimulation of the plantar surface of the foot with the Korvit boots. The Korvit stimulator was used through two different modes, namely an organized (“gait like”) sequence and a destructured (chaotic) pattern. Eighteen right-handed young healthy volunteers were recruited (mean age, 27 ± 4.7 years). Mental imagery activated a broad neuronal network including the supplementary motor area-proper (SMA-proper), pre-SMA, the dorsal premotor cortex, ventrolateral prefrontal cortex, anterior insula, and precuneus/superior parietal areas. The mechanical plantar stimulation activated the primary sensorimotor cortex and secondary somatosensory cortex bilaterally. The paradigms generated statistically common areas of activity, notably bilateral SMA-proper and right pre-SMA, highlighting the potential key role of SMA in gait control. There was no difference between the organized and chaotic Korvit sequences, highlighting the difficulty of developing a walking-specific plantar stimulation paradigm. In conclusion, this combined-fMRI paradigm combining mental imagery and gait-like plantar stimulation provides complementary information regarding gait-related brain activity and appears useful for the assessment of high-level gait control.
Advances in Diagnosis of Respiratory Diseases of Small Ruminants

Irrespective of aetiology, infectious respiratory diseases of sheep and goats contribute to 5.6 percent of the total diseases of small ruminants. These infectious respiratory disorders are divided into two groups: the diseases of upper respiratory tract, namely, nasal myiasis and enzootic nasal tumors, and diseases of lower respiratory tract, namely, peste des petits ruminants (PPR), parainfluenza, Pasteurellosis, Ovine progressive pneumonia, mycoplasmosis, caprine arthritis encephalitis virus, caseous lymphadenitis, verminous pneumonia, and many others. Depending upon aetiology, many of them are acute and fatal in nature. Early, rapid, and specific diagnosis of such diseases holds great importance to reduce the losses. The advanced enzyme-linked immunosorbent assays (ELISAs) for the detection of antigen as well as antibodies directly from the samples and molecular diagnostic assays along with microsatellites comprehensively assist in diagnosis as well as treatment and epidemiological studies. The present review discusses the advancements made in the diagnosis of common infectious respiratory diseases of sheep and goats. It would update the knowledge and help in adapting and implementing appropriate, timely, and confirmatory diagnostic procedures. Moreover, it would assist in designing appropriate prevention protocols and devising suitable control strategies to overcome respiratory diseases and alleviate the economic losses.
The Secret to Job Satisfaction is Low Expectations: How Perceived Working Conditions Differ from Actual Ones

Working conditions exert a major influence on accidents and illnesses at work as well as on job satisfaction and health, yet very little research has examined the determinants of working conditions. By exploiting the Italian Labour Force Survey, this paper provides evidence on the underlying factors affecting working conditions. It provides a behavioural interpretation of the results, which stems from the discrepancy between actual and expected working conditions. In light of this interpretation, workers would declare their perceived working conditions influenced by the difference between the actual and the expected working conditions. Variables concerning personal characteristics, such as gender, education and being employed in the first job, shift expectations about working conditions and accordingly perceived working conditions. On the contrary, variables related to work characteristics, such as working full time, with shifts and in a large place, affect actual and thus perceived working conditions (negatively).
Digital Signal Processing

Second order total variation (SOTV) models have advantages for image restoration over their ﬁrst order counterparts including their ability to remove the staircase artefact in the restored image. However, such models tend to blur the reconstructed image when discretised for numerical solution [1–5]. To overcome this drawback, we introduce a new tensor weighted second order (TWSO) model for image restoration. Speciﬁcally, we develop a novel regulariser for the SOTV model that uses the Frobenius norm of the product of the isotropic SOTV Hessian matrix and an anisotropic tensor. We then adapt the alternating direction method of multipliers (ADMM) to solve the proposed model by breaking down the original problem into several subproblems. All the subproblems have closed-forms and can be solved eﬃciently. The proposed method is compared with state-of-the-art approaches such as tensor-based anisotropic diffusion, total generalised variation, and Euler’s elastica. We validate the proposed TWSO model using extensive experimental results on a large number of images from the Berkeley BSDS500. We also demonstrate that our method effectively reduces both the staircase and blurring effects and outperforms existing approaches for image inpainting and denoising applications. © 2017 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
On the Ramsey Class of Interleavers for Robust Speech Recognition in Burst-Like Packet Loss

This paper focuses on the application of the Ramsey class of interleavers to the problem of achieving robust distributed speech recognition in the presence of burst-like packet loss. Although block interleavers of minimal latency have been already proposed by other authors in order to cope with this problem, the Ramsey class offers a more powerful kind of interleavers. Taking into account the behavior of the error concealment techniques commonly used in these recognition systems, it is possible to design Ramsey interleavers which, in comparison with the block interleavers of minimal latency, can counteract longer bursts with the same latency and thus improve the robustness of the recognition system. The effectiveness of the proposed design criterion is verified by means of simulations and experimental comparisons
Pitch Sequence Complexity and Long-Term Pitcher Performance

Winning one or two games during a Major League Baseball (MLB) season is often the difference between a team advancing to post-season play, or “waiting until next year”. Technology advances have made it feasible to augment historical data with in-game contextual data to provide managers immediate insights regarding an opponent’s next move, thereby providing a competitive edge. We developed statistical models of pitcher behavior using pitch sequences thrown during three recent MLB seasons (2011–2013). The purpose of these models was to predict the next pitch type, for each pitcher, based on data available at the immediate moment, in each at-bat. Independent models were developed for each player’s most frequent four pitches. The overall predictability of next pitch type is 74:5%. Additional analyses on pitcher predictability within specific game situations are discussed. Finally, using linear regression analysis, we show that an index of pitch sequence predictability may be used to project player performance in terms of Earned Run Average (ERA) and Fielding Independent Pitching (FIP) over a longer term. On a restricted range of the independent variable, reducing complexity in selection of pitches is correlated with higher values of both FIP and ERA for the players represented in the sample. Both models were significant at the α = 0.05 level (ERA: p = 0.022; FIP: p = 0.0114). With further development, such models may reduce risk faced by management in evaluation of potential trades, or to scouts assessing unproven emerging talent. Pitchers themselves might benefit from awareness of their individual statistical tendencies, and adapt their behavior on the mound accordingly. To our knowledge, the predictive model relating pitch-wise complexity and long-term performance appears to be novel.
Gender Differences in the Perception of Love and Sex among Polish Young Adults

The aim of the study was to investigate gender differences in the perception of love and sex among Polish young adults. The Perception of Love and Sex Scale was administered to the sample 494 young adults (327 females and 167 males) aged 20–28 years, with the average age of participants being 21.3 (SD = 1.93). The results indicated that women were less convinced that love is the primary entity (i.e., Love is Most Important), that sex is an important element of a romantic relationship, but in some ways subsumed by love (i.e., Sex Demonstrates Love), and that love comes first (i.e., Love Comes Before Sex).
Vowel recognition using First Formant Feature

Automatic speech recognition (ASR) has made great strides with the development of digital signal processing hardware and software especially using English as the language of choice. In this paper, a new feature extraction method is presented to identify vowels recorded from 80 Malaysian speakers. The features are obtained from Vocal Tract Model based on Bandwidth (BW) approach. Bandwidth approach identifies frequency ranges from the first formant peak of vowel spectrum. Mean magnitudes were calculated from these Bandwidth frequency ranges. Classification results from Bandwidth Approach were then compared with 13 MFCC Coefficients. A BPNN were used to classify the vowels. BW obtained a classification accuracy of 89.58%, which is 0.71% better than MFCC.
Evaluation of Hemifield Sector Analysis Protocol in Multifocal Visual Evoked Potential Objective Perimetry for the Diagnosis and Early Detection of Glaucomatous Field Defects

Purpose Multifocal visual evoked potential (mfVEP) is a newly introduced method used for objective visual field assessment. Several analysis protocols have been tested to identify early visual field losses in glaucoma patients using the mfVEP technique, some were successful in detection of field defects, which were comparable to the standard automated perimetry (SAP) visual field assessment, and others were not very informative and needed more adjustment and research work. In this study we implemented a novel analysis approach and evaluated its validity and whether it could be used effectively for early detection of visual field defects in glaucoma. Methods Three groups were tested in this study; normal controls (38 eyes), glaucoma patients (36 eyes) and glaucoma suspect patients (38 eyes). All subjects had a two standard Humphrey field analyzer (HFA) test 24-2 and a single mfVEP test undertaken in one session. Analysis of the mfVEP results was done using the new analysis protocol; the hemifield sector analysis (HSA) protocol. Analysis of the HFA was done using the standard grading system. Results Analysis of mfVEP results showed that there was a statistically significant difference between the three groups in the mean signal to noise ratio (ANOVA test, p < 0.001 with a 95% confidence interval). The difference between superior and inferior hemispheres in all subjects were statistically significant in the glaucoma patient group in all 11 sectors (t-test, p < 0.001), partially significant in 5 / 11 (t-test, p < 0.01), and no statistical difference in most sectors of the normal group (1 / 11 sectors was significant, t-test, p < 0.9). Sensitivity and specificity of the HSA protocol in detecting glaucoma was 97% and 86%, respectively, and for glaucoma suspect patients the values were 89% and 79%, respectively. Conclusions The new HSA protocol used in the mfVEP testing can be applied to detect glaucomatous visual field defects in both glaucoma and glaucoma suspect patients. Using this protocol can provide information about focal visual field differences across the horizontal midline, which can be utilized to differentiate between glaucoma and normal subjects. Sensitivity and specificity of the mfVEP test showed very promising results and correlated with other anatomical changes in glaucoma field loss.
Impact of soil drought stress on photochemical efficiency of photosystem II and antioxidant enzyme activities of Phaseolus vulgaris cultivars

Common bean (Phaseolus vulgaris L.) cultivars (cvs) (Goynuk 98, Karacasehir 90, Şehirali 90, ES 855, and Yunus 90) were subjected to drought stress in order to assess the levels of drought tolerance through the analysis of growth parameters, leaf water potential (yleaf), stomatal conductance (gs), chlorophyll (chl) content, and lipid peroxidation. Significant differences were recorded among cultivars in most traits. Yunus 90 was identified as the most tolerant, and Karacasehir 90 was the most sensitive. Furthermore, the changes in antioxidant enzyme activities, H2O2 content, and Photosystem II were investigated under drought stress, where Antioxidant enzyme activities increased while H2O2 contents decreased. In Yunus 90, increases in catalase (CAT) and ascorbate peroxidase (APX) activities were higher than those of the other cvs. Increase in GPX activity was higher in Karacasehir 90 compared to Yunus 90. Drought stress reduced quantum yield of PS II photochemistry (fPSII) and photochemical quenching (qP) in all cultivars. The reduction was more pronounced in Karacasehir 90. These results showed that different common bean cvs had different photochemical efficiencies and used different antioxidant enzymes in order to scavenge reactive oxygen species.
Health status of Gypsy Travellers.

BACKGROUND Although previous studies suggest that Gypsy Travellers have poorer health status and excess mortality compared with the general population, there is no epidemiological evidence using validated measures in this nomadic ethnic group. The aim of this study was to compare the health status of traditional Gypsy Travellers with norms from the UK population, and with a concurrent comparison group using the Euroqol health status measure (EQ-5D). METHODS Eighty-seven adult Gypsy Travellers were matched for age and sex with English or Irish residents, registered with an urban general practice in an area of high social deprivation. Both samples completed the EQ-5D questionnaire by interview. A comparison was also made with normative data from the UK general population. RESULTS Travellers had poorer health status than their settled counterparts on two of the five dimensions (mobility and activity) but not on the overall summary score. Travellers reported significantly poorer health than the matched comparison group on the EQ-5D visual analogue scale. Both the Travellers and the comparison group had much poorer health status on the EQ-5D index than the UK population norms, even when compared with the lowest socioeconomic group. CONCLUSIONS Health status of Gypsy Travellers was significantly poorer than in the lowest socio-economic UK population group, but was not so markedly different from a concurrent, matched, socially deprived resident group. Gypsy Travellers did have poorer health status than matched comparators in relation to mobility, activity and perception of overall health. Quantitative assessment of health status in the Traveller community is feasible.