Miracle-dz/UniFAR-FTUs huggingface dataset:
Can Deep Learning Revolutionize Mobile Sensing?

Sensor-equipped smartphones and wearables are transforming a variety of mobile apps ranging from health monitoring to digital assistants. However, reliably inferring user behavior and context from noisy and complex sensor data collected under mobile device constraints remains an open problem, and a key bottleneck to sensor app development. In recent years, advances in the field of deep learning have resulted in nearly unprecedented gains in related inference tasks such as speech and object recognition. However, although mobile sensing shares many of the same data modeling challenges, we have yet to see deep learning be systematically studied within the sensing domain. If deep learning could lead to significantly more robust and efficient mobile sensor inference it would revolutionize the field by rapidly expanding the number of sensor apps ready for mainstream usage. In this paper, we provide preliminary answers to this potentially game-changing question by prototyping a low-power Deep Neural Network (DNN) inference engine that exploits both the CPU and DSP of a mobile device SoC. We use this engine to study typical mobile sensing tasks (e.g., activity recognition) using DNNs, and compare results to learning techniques in more common usage. Our early findings provide illustrative examples of DNN usage that do not overburden modern mobile hardware, while also indicating how they can improve inference accuracy. Moreover, we show DNNs can gracefully scale to larger numbers of inference classes and can be flexibly partitioned across mobile and remote resources. Collectively, these results highlight the critical need for further exploration as to how the field of mobile sensing can best make use of advances in deep learning towards robust and efficient sensor inference.
High quality graph partitioning

We present an overview over our graph partitioners KaFFPa (Karlsruhe Fast Flow Partitioner) and KaFFPaE (KaFFPa Evolutionary). KaFFPa is a multilevel graph partitioning algorithm which on the one hand uses novel local improvement algorithms based on max-flow and min-cut computations and more localized FM searches and on the other hand uses more sophisticated global search strategies transferred from multi-grid linear solvers. KaFFPaE is a distributed evolutionary algorithm to solve the Graph Partitioning Problem. KaFFPaE uses KaFFPa which provides new effective crossover and mutation operators. By combining these with a scalable communication protocol we obtain a system that is able to improve the best known partitioning results for many inputs.
Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro

T lymphocytes develop in the thymus from immunologically naive bone marrow precursors. Based on T cell receptor rearrangement and transcription, and thymic reconstitution potential, we have deduced a developmental sequence among immature thymocytes, before the acquisition of the lineage markers CD3, CD4, and CD8. In the current study, we have followed the ontogenic progression of the latter stages in this sequence, using two different systems: (a) in vivo, by direct injection into the thymus of nonirradiated, congenic recipients; and (b) in vitro, using culture medium without mitogens or cytokines. In vivo, the less mature Pgp-1- interleukin 2 receptor alpha-positive (IL- 2R alpha+) CD3-4-8- subset (also heat-stable antigen high) requires 3 d before becoming predominantly IL-2R alpha- CD3lo4+ 8+ typical cortical- type cells, and at least 5 d before the appearance of any mature single- positive cells (CD3hi4+ 8- or CD3hi4-8+). However, these Pgp-1- IL-2R alpha+ precursors do not differentiate further in unstimulated culture. The more mature Pgp-1- IL-2R alpha- CD3-4-8- subset becomes primarily CD3lo4+ 8+ within 1 d after transplantation, and some mature single- positive progeny are evident by day 3. By 5 d, most of these Pgp-1-IL- 2R alpha- precursor cells have become CD3hi, and have lost or are downregulating either CD4 or CD8. In culture, these Pgp-1- IL-2R alpha- cells also acquire high levels of CD4 and CD8 within 1 d, and low levels of CD3 by 2 d. However, they do not progress further to mature single positives in vitro, and most of them die by day 3. These experiments directly confirm our previously proposed developmental sequence, and demonstrate the kinetics of T lymphocyte production in a low-stress, steady-state environment.
The estimation of time delay and Doppler stretch of wideband signals

The problem of estimating the time delay and the Doppler stretch for wideband signals from a moving target is considered. The Cramer-Rao bound and the maximum likelihood (ML) method of estimation are derived. Due to the uncertainty of the reflection coefficient, the ML method may not be practicable. An alternative method involving the location of the peak of the wideband ambiguity function of the signal is suggested. The performance of the method is analysed, and, under high signal-to-noise ratios (SNRs), the method is asymptotically unbiased, and the variances of the estimates are closed to the Cramer-Rao bound for a large variety of signals. Optimum signals for the joint estimation of the time delay and the Doppler stretch under practical constraints are designed and, through computer simulations, their performance are shown to be superior to the commonly used signals. >
Ibrutinib does not affect ristocetin-induced platelet aggregation evaluated by light transmission aggregometry in chronic lymphocytic leukemia patients

Ibrutinib (IBR) is an irreversible inhibitor of Bruton’s tyrosine kinase (Btk) which is approved for the treatment of chronic lymphocytic leukemia (CLL). Clinically significant bleedings attributed to platelet inhibition by IBR have been reported and there is great interest toward development of
The Long-Term Impact of Emotional Abuse in Childhood

Until recently there has been limited attention paid to the long-term consequences of childhood emotional abuse (also known as psychological abuse), in contrast to the significant attention paid to the long-term effects of childhood physical or sexual abuse (Barnett, Miller-Perrin, & Perrin, 2005; Binggeli, Hart, & Brassard, 2001). In part this has been because emotional abuse was not recognized as a distinct form of child maltreatment until quite recently, and there has been considerable difficulty defining and assessing emotional abuse. Unlike physical abuse,
StreamFlow 1.0: an extension to the spatially distributed snow model Alpine3D for hydrological modelling and deterministic stream temperature prediction

Abstract. Climate change is expected to strongly impact the hydrological and thermal regimes of Alpine rivers within the coming decades. In this context, the development of hydrological models accounting for the specific dynamics of Alpine catchments appears as one of the promising approaches to reduce our uncertainty of future mountain hydrology. This paper describes the improvements brought to StreamFlow, an existing model for hydrological and stream temperature prediction built as an external extension to the physically based snow model Alpine3D. StreamFlow's source code has been entirely written anew, taking advantage of object-oriented programming to significantly improve its structure and ease the implementation of future developments. The source code is now publicly available online, along with a complete documentation. A special emphasis has been put on modularity during the re-implementation of StreamFlow, so that many model aspects can be represented using different alternatives. For example, several options are now available to model the advection of water within the stream. This allows for an easy and fast comparison between different approaches and helps in defining more reliable uncertainty estimates of the model forecasts. In particular, a case study in a Swiss Alpine catchment reveals that the stream temperature predictions are particularly sensitive to the approach used to model the temperature of subsurface flow, a fact which has been poorly reported in the literature to date. Based on the case study, StreamFlow is shown to reproduce hourly mean discharge with a Nash–Sutcliffe efficiency (NSE) of 0.82 and hourly mean temperature with a NSE of 0.78.
Atomic processes for astrophysical plasmas

In this review we summarize the recent calculations and improvements of atomic data that we have carried out for the analysis of astrophysical spectroscopy within the atomic processes for astrophysical plasmas network. We briefly discuss the various methods used for the calculations, and highlight several issues that we have uncovered during such extensive work. We discuss the completeness and accuracy of the cross sections for ionic excitation by electron impact for the main isoelectronic sequences, which we have obtained with large-scale calculations. Given its astrophysical importance, we emphasize the work on iron. Some examples on the significant improvement that has been achieved over previous calculations are provided.
Wind Power Generation System with Induction Machine and Diode Rectifier

This paper investigates advantages of new combination of the induction generator for wind power and the power electronic equipments. Induction generator is popularly used for the wind power generation. The disadvantage of it is impossible to generate power at the lower rotor speed than the synchronous speed. To compensate this disadvantage, expensive synchronous generator with the permanent magnets sometimes used. If HVDC transmission is used to connect the offshore wind farm to the mainland, using AC/DC converter system is no more disadvantageous. However, to omit the expensive permanent magnet is desirable. In proposed scheme, the diode rectifier is used to convert the real power from the induction generator to the intermediate DC voltage, while the reactive power necessary to excite the induction generator only is supplied from the voltage source converter (VSC). This means that the rating of the expensive VSC is minimized and total cost of the wind power generation system is decreased compared to the system with synchronous generator
Activation of dopamine cell firing by repeated L-DOPA administration to dopamine-depleted rats: its potential role in mediating the therapeutic response to L-DOPA treatment

The administration of L-dihydroxyphenylalanine (L-DOPA) to patients with Parkinson's disease is known to produce acute effects that include the reduction of rigidity as well as delayed therapeutic actions involving the resumption of complex motor behavior. In order to examine the potential role of dopamine (DA) cell activity in mediating these responses, the effects of acute and repeated L-DOPA administration on the electrophysiological activity of the residual dopamine (DA) neurons were examined in rats that had received partial 6-hydroxydopamine (6- OHDA)-induced DA lesions. DA cell activity was assessed along three dimensions: (1) the relative proportion of DA neurons exhibiting spontaneous spike firing, (2) their basal firing rate, and (3) their firing pattern. Following 6-OHDA-induced DA depletion, rats were treated for 1 month with saline or L-DOPA. In addition, rats from each group received either an acute injection of L-DOPA or saline on the day of recording. In rats receiving repeated saline treatment, the DA neurons recorded following acute L-DOPA administration were firing at significantly slower basal firing rates and exhibited less burst firing when compared to saline-pretreated rats given acute saline. In contrast, DA cells recorded from rats that had received repeated L-DOPA administration for 4 weeks followed by an acute saline injection did not exhibit any significant differences from DA cells of intact control rats with respect to basal firing rate or firing pattern; however, there was a substantial increase in the proportion of DA neurons exhibiting spontaneous spike firing after correcting for 6-OHDA-induced cell loss. In addition, in rats receiving repeated L-DOPA treatment, the DA cells recorded following acute administration of L-DOPA showed significantly less of a reduction in firing rate when compared to the cells recorded following acute L-DOPA in the saline treatment group. These results show that: (1) acute L-DOPA administration appears to exert its actions by DA autoreceptor stimulation, whereas (2) repeated L-DOPA administration increases the proportion of spontaneously active DA neurons in partially lesioned rats. As a result, repeated L-DOPA administration would be expected to cause an increase in spike- dependent DA release as a consequence of the greater proportion of DA cells showing spontaneous activity. This may be the major factor underlying the delayed therapeutic benefits of L-DOPA therapy in the treatment of Parkinson's disease.
Chromatin structure and transcriptional regulation of human papillomavirus type 18 DNA in hela cells

Mapping analysis of the nucleosomal organization of integrated human papillomavirus type 18(HPV 18) DNA in HeLa cells reveals a very prominent nuclease‐hypersensitive site within the viral noncoding regulatory region that harbors transcriptional control sequences and coincides with most of the 5′ ends of the cytoplasmic early mRNAs. Moreover, it is shown that the conserved coamplified 5′ cellular flank, common to all HPV18 copies in HeLa cells and located close to the virus‐cell integration site, also contains several distinct hypersensitive sites, accessible not only to DNase I but also to restriction enzymes. Nuclear run‐on analysis in isolated HeLa nuclei demonstrates the occurrence of nascent transcripts covering the cellular flank (the late and the viral noncoding regulatory region), indicating that a cellular promoter, marked by the hypersensitive sites, cooperates with the viral control region in generating the HPV18 transcripts.
Concrete Pavement Mixture Design and Analysis (MDA): An Innovative Approach To Proportioning Concrete Mixtures

Mixture proportioning is routinely a matter of using a recipe based on a previously produced concrete, rather than adjusting the proportions based on the needs of the mixture and the locally available materials. As budgets grow tighter and increasing attention is being paid to sustainability metrics, greater attention is beginning to be focused on making mixtures that are more efficient in their usage of materials yet do not compromise engineering performance. Therefore, a performance-based mixture proportioning method is needed to provide the desired concrete properties for a given project specification. The proposed method should be user friendly, easy to apply in practice, and flexible in terms of allowing a wide range of material selection. The objective of this study is to further develop an innovative performance-based mixture proportioning method by analyzing the relationships between the selected mix characteristics and their corresponding effects on tested properties. The proposed method will provide step-by-step instructions to guide the selection of required aggregate and paste systems based on the performance requirements. Although the provided guidance in this report is primarily for concrete pavements, the same approach can be applied to other concrete applications as well.
Early adolescents and “going out”

Although it is clear that early adolescents pursue and establish romantic relationships, less is known about the hallmarks of these pairings, even though they are linked to current and future close relationships. Based on adolescent identity formation and identity theory, we used theoretical concepts of roles, role expectations, and role enactments to inform our study. We conducted a series of same-sex and same-age focus groups with sixth and eighth graders and analyzed their responses using a grounded theory approach. We found that early adolescent romantic role enactments could be aggregated into two broad types of experiences. On the one hand, some youth were uncomfortable with interacting with a romantic partner. They often relied on texting as opposed to face-to-face interactions with partners. On the other hand, other early adolescents were more at ease engaging in romantic roles. They spent time interacting with their partners, shared personal information with each other, were physically affectionate, and created boundaries that defined their romantic relationships as different from other close relationships. The findings support our assertion that when early adolescents enact the new role of “romantic partner,” and develop a personal set of role expectations for this role, it requires learning, direct experience, and maturation before they can successfully engage in this role.
SiO2 Free HfO2 Gate Dielectrics by Physical Vapor Deposition

HfO<sub>2</sub> layers, 25-Å thick, were grown by cyclic Hf sputter deposition and room temperature oxidation steps on chemically oxidized Si(001). Subsequent in situ annealing and TiN deposition yield a high-κ gate-stack for which the original 8-Å-thick SiO<sub>2</sub> layer is eliminated, as confirmed by transmission electron microscopy. Transistors fabricated with this gate-stack achieve an equivalent oxide thickness in inversion T<sub>inv</sub> =9.7 Å, with a gate leakage J<sub>g</sub> =0.8 A/cm<sup>2</sup>. Devices fabricated without in situ annealing of the HfO<sub>2</sub> layer yield a T<sub>inv</sub> which increases from 10.8 to 11.2 Å as the oxidation time during each HfO<sub>2</sub> growth cycle increases from 10 to 120 s, also causing a decrease in J<sub>g</sub> from 0.95 to 0.60 A/cm<sup>2</sup>, and an increase in the transistor threshold voltage from 272 to 294 mV. The annealing step reduces T<sub>inv</sub> by 1.5 Å (10%) but also increases the gate leakage by 0.1 A/cm<sup>2</sup> (30%), and causes a 61 mV reduction in V<sub>t</sub>. These effects are primarily attributed to the oxygen-deficiency of the as-deposited HfO<sub>2</sub>, which facilitates both the reduction of an interfacial SiO<sub>2</sub> layer and a partial phase transition to a high-κ cubic or tetragonal HfO<sub>2</sub> phase.
Threat of Foreign Arthropod-Borne Pathogens to Livestock in the United States

Abstract There are many exotic animal pathogens throughout the world that, if introduced into the United States, could have a significant detrimental impact on the health of livestock, agricultural economy, the environment, and public health. Many of these pathogens are arthropod-borne and potential vectors are readily available in the United States. A number of these arthropod-borne pathogens are discussed here as examples that illustrate the potential risk and the consequences of inadvertent introductions. Several International agencies have a role in global surveillance and in controlling animal diseases should they begin to expand their range. The risk to the United States is considerable. We propose that the United States invest in the improved infrastructure needed to reduce the risk of foreign arthropod-borne pathogens. Current U.S. programs focus on the exclusion of pathogens through regulation of animal movements and products, surveillance, especially trained animal disease diagnosticians, research support, international cooperation and, should pathogens enter our country, the resources for their prompt eradication. We suggest that the United States needs to develop a comprehensive, updated strategic plan to assess all aspects of current and future requirements, objectives, and resources needed to protect its national interests.
A pathway to enhancing professionalism: Building a bridge between TAFE and university early childhood qualifications

IT HAS BEEN ARGUED that a key strategy to improve developmental and educational outcomes for young children is to increase the number of childcare staff with early childhood university degrees (Saracho & Spodek, 2007). In order to upgrade the qualifications of staff, a number of Australian universities provide pathways that enable graduates of early childhood diploma programs to complete a degree. Several impediments, including institutional structures and individual contextual and personal factors, may affect these pathways. Although a range of organisations offer diploma programs, TAFE (Tertiary and Further Education) is a major provider. The aim of the present study was to investigate student transition between early childhood programs in TAFE and university. The research drew on several data sources, including a survey of the perceptions of students at various points of undertaking the transition. The current credit arrangement for TAFE Diploma graduates was found to be satisfactory; however, gaps were identified between the TAFE and university teaching and learning arrangements with regard to curriculum structures, teaching styles and assessment. Graduates of both programs considered that the completion of both awards would have a positive effect on their careers.
FcRγ-Chain ITAM Signaling Is Critically Required for Cross-Presentation of Soluble Antibody–Antigen Complexes by Dendritic Cells

The uptake of Ag–Ab immune complexes (IC) after the ligation of activating FcγR on dendritic cells (DC) leads to 100 times more efficient Ag presentation than the uptake of free Ags. FcγRs were reported to facilitate IC uptake and simultaneously induce cellular activation that drives DC maturation and mediates efficient T cell activation. Activating FcγRs elicit intracellular signaling via the ITAM domain of the associated FcRγ-chain. Studies with FcRγ-chain knockout (FcRγ−/−) mice reported FcRγ-chain ITAM signaling to be responsible for enhancing both IC uptake and DC maturation. However, FcRγ-chain is also required for surface expression of activating FcγRs, hampering the dissection of ITAM-dependent and independent FcγR functions in FcRγ−/− DCs. In this work, we studied the role of FcRγ-chain ITAM signaling using DCs from NOTAM mice that express normal surface levels of activating FcγR, but lack functional ITAM signaling. IC uptake by bone marrow–derived NOTAM DCs was reduced compared with wild-type DCs, but was not completely absent as in FcRγ−/− DCs. In NOTAM DCs, despite the uptake of ICs, both MHC class I and MHC class II Ag presentation was completely abrogated similar to FcRγ−/− DCs. Secretion of cytokines, upregulation of costimulatory molecules, and Ag degradation were abrogated in NOTAM DCs in response to FcγR ligation. Cross-presentation using splenic NOTAM DCs and prolonged incubation with OVA-IC was also abrogated. Interestingly, in this setup, proliferation of CD4+ OT-II cells was induced by NOTAM DCs. We conclude that FcRγ-chain ITAM signaling facilitates IC uptake and is essentially required for cross-presentation, but not for MHC class II Ag presentation.