Miracle-dz/UniFAR-FTUs huggingface dataset:
SEATH-A NEW TOOL FOR AUTOMATED FEATURE EXTRACTION IN THE CONTEXT OF OBJECT-BASED IMAGE ANALYSIS

: In order to avoid the time-consuming trial-and-error practice for seeking signiﬁcant features for optimal class separation in object-based classiﬁcation, an automatic feature extraction methodology, called SEaTH has been developed. SEaTH calculates the SEperability and the corresponding THresholds of object classes for any number of given features on the basis of a statistical approach. The statistical measure for determining the representative features for each object class is the mutual separability of the object classes. Subsequently, SEaTH calculates those thresholds which allow the best separability in the selected features. The methodology and its application to a case study on an Iranian nuclear facility are presented. With regard to the automation of object-based image processing, aspects of standardization and transferability are discussed.
Carriers in electron transport from molecular hydrogen to oxygen in Rhizobium japonicum bacteroids

An investigation has been conducted to identify electron transport carriers that participate in the oxidation of H2 by H2 uptake-positive strains of Rhizobium japonicum bacteroids. We have observed that the reduced form of dibromothymoquinone at a concentration of 0.2 mM strongly inhibited H2 uptake, endogenous respiration, and C2H2 reduction by bacteroid suspensions. Reduced dibromothymoquinone, however, failed to inhibit the transfer of electrons from H2 to methylene blue under anaerobic conditions, indicating that the hydrogenase per se is insensitive to this inhibitor. Metronidazole, at 1 mM, affected rates of H2 uptake and endogenous respiration only slightly, but strongly inhibited C2H2 reduction. Evidence for H2-dependent cytochrome reduction in an H2 uptake-positive strain of R. japonicum bacteroids is presented. In kinetic studies, the rates of reduction of the type b and c cytochromes in the presence of H2 were shown to be severalfold higher than the rates due to endogenous respiration alone. With hydrogenase-deficient mutants of R. japonicum, no measurable effect of H2 on cytochrome reduction was observed. Our results indicate that ubiquinone and cytochromes of types b and c are involved in the oxyhydrogen reaction in R. japonicum.
Cardiovascular adaptations to intense swim training in sedentary middle-aged men and women.

Central and peripheral cardiovascular adaptations to 12 weeks of intense swim training were characterized in 12 previously sedentary middle-aged men and women. Peak oxygen uptake (VO2) during upright bicycle exercise improved from 29.2 +/- 5.6 to 34.7 +/- 6.7 ml/kg/min (mean +/- SD, p less than .01) because of similar increases in peak cardiac output (CO) and calculated arteriovenous oxygen difference (both p = .02). Peak supine VO2 was 10% higher after training (p less than .005) solely because of enhanced CO (p = .005). Peak heart rate decreased in both postures; therefore stroke volume at peak exercise was greater by 10% and 18% in the upright and supine postures, respectively (p = .05 and p = .005). There was an identical 18% rise (p = .01) in peak supine left ventricular end-diastolic volume index by radionuclide ventriculography but no change in left ventricular ejection fraction or end-systolic volume index (ESVI). Peak systolic blood pressure (SBP) was unchanged in the upright posture but was 8% higher (p = .002) during recumbency despite a similar total peripheral resistance and SBP/ESVI ratio. Maximal calf conductance (Gmax), assessed separately by venous occlusion plethysmography after local ischemic exercise to fatigue, was augmented 20% (p less than .02) by training, resulting in an 18% greater hyperemic blood flow (p = .05). Peak VO2, CO, and Gmax were unchanged in five nonexercising control subjects. We conclude that in middle-aged humans, intense swim training for 12 weeks produces adaptations that include a greater capacity for vasodilatation in skeletal muscle and an enhanced cardiac pump capacity.
Human leukocyte antigen B27 and B51 double-positive Behçet uveitis.

OBJECTIVES To describe the clinical characteristics of human leukocyte antigen (HLA) B27 and B51 double-positive Behçet uveitis and to determine whether the coexistence of HLA-B27 can affect Behçet uveitis. METHODS We retrospectively reviewed the medical records of patients with Behçet uveitis and patients with HLA-B27-associated non-Behçet uveitis who underwent HLA-B27 and HLA-B51 typing and were followed up for more than 3 years. We divided the patients into 3 groups according to HLA-B27/B51 status and compared the clinical outcomes. Main outcome measures were demographic features, uveitis characteristics, complications, treatments, and visual prognosis. RESULTS Fourteen patients with HLA-B27(+)B51(+) Behçet uveitis, 43 patients with HLA-B27(-)B51(+) Behçet uveitis, and 41 patients with HLA-B27(+)B51(-) non-Behçet uveitis were identified. HLA-B27(+)B51(+) Behçet uveitis showed the demographic features similar to HLA-B27(-) counterparts. However, HLA-B27(+)B51(+) Behçet uveitis showed less involvement of posterior segments, a less chronic course, fewer complications in posterior segments, and less use of systemic medication or surgical intervention for inflammatory control, similar to HLA-B27(+)B51(-) non-Behçet uveitis. The long-term vision prognosis of HLA-B27(+)B51(+) Behçet uveitis was more favorable than that of HLA-B27(-)B51(+) Behçet uveitis. CONCLUSIONS Our results indicate that HLA-B27(+)B51(+) Behçet uveitis is a benign subgroup of Behçet uveitis. The positivity of HLA-B27 may be a good prognostic factor in Behçet uveitis.
HR-Cosmos: Kinematics of Star-Forming Galaxies at z $\sim$ 0.9

We present the kinematic analysis of a sub-sample of 82 galaxies at $\mathrm{0.75<z<1.2}$ from our new survey HR-COSMOS aimed to obtain the first statistical study on the kinematics of star-forming galaxies in the treasury COSMOS field at $\mathrm{0<z<1.2}$. We observed $\sim\,$766 emission line galaxies using the multi-slit spectrograph ESO-VLT/VIMOS in high-resolution mode (R=2500). To better extract galaxy kinematics, VIMOS spectral slits have been carefully tilted along the major axis orientation of the galaxies, making use of the position angle measurements from the high spatial resolution ACS/HST COSMOS images. We constrained the kinematics of the sub-sample at $0.75<z<1.2$ by creating high resolution semi-analytical models. We established the stellar-mass Tully-Fisher relation at $z\simeq 0.9$ with high-quality stellar mass measurements derived using the latest COSMOS photometric catalog, which includes the latest data releases of UltraVISTA and Spitzer. In doubling the sample at these redshifts compared with the literature, we estimated the relation without setting its slope, and found it consistent with previous studies in other deep extragalactic fields assuming no significant evolution of the relation with redshift at $z\lesssim1$. We computed dynamical masses within the radius R$_{2.2}$ and found a median stellar-to-dynamical mass fraction equal to 0.2 (assuming Chabrier IMF), which implies a contribution of gas and dark matter masses of 80% of the total mass within R$_{2.2}$, in agreement with recent integral field spectroscopy surveys. We find no dependence of the stellar-mass Tully-Fisher relation with environment probing up to group scale masses. This study shows that multi-slit galaxy surveys remain a powerful tool to derive kinematics for large numbers of galaxies at both high and low redshift.
A subunit of the mediator complex regulates vertebrate neuronal development

The unique profiles of gene expression dictate distinct cellular identity. How these profiles are established during development is not clear. Here we report that the mutant motionless (mot), identified in a genetic screen for mutations that affect neuronal development in zebrafish, displays deficits of monoaminergic neurons and cranial sensory ganglia, whereas expression of the pan-neuronal marker Hu is largely unperturbed; GABAergic and subsets of cranial motor neurons do not appear to be deficient. Positional cloning reveals that mot encodes Med12, a component of the evolutionarily conserved Mediator complex, whose in vivo function is not well understood in vertebrates. mot/med12 transcripts are enriched in the embryonic brain and appear distinct from two other Mediator components Med17 and Med21. Delivery of human med12 RNA into zebrafish restores normality to the mot mutant and, strikingly, leads to premature neuronal differentiation and an increased production of monoaminergic neuronal subtypes in WT. Further investigation reveals that mot/med12 is necessary to regulate, and when overexpressed is capable of increasing, the expression of distinct neuronal determination genes, including zash1a and lim1, and serves as an in vivo cofactor for Sox9 in this process. Together, our analyses reveal a regulatory role of Mot/Med12 in vertebrate neuronal development.
Regenerative Injection Therapy (Prolotherapy) for Hip Labrum Lesions:Rationale and Retrospective Study

Background: Acetabular labral tear is a debilitating condition for which there are few effective non-surgical treatment options. A number of studies in humans and in animal models suggest that the labrum may have a capacity for spontaneous healing, and that therapies that seek to exploit and facilitate this process may be beneficial. Regenerative injection therapies have shown promise in the treatment of several musculoskeletal disorders, but have not previously been applied to labral tear. Methods: We present an initial case series of 19 patients with labral tear that were treated in our clinic with intra-articular injections of hypertonic dextrose. Patient-reported assessments were collected by questionnaire between 1 and 60 months post-treatment (mean = 12 months). Results: All patients reported improvements in pain relief and functionality. Patients reported complete relief of 54% of recorded symptoms. Improvements did not show dependence on the time between treatment and follow-up. No adverse events were reported. Conclusions: Regenerative injection therapy (prolotherapy) for acetabular labral tear appears to be a safe and potentially efficacious procedure that merits further investigation as a non-surgical option.
TOWARDS AN ONTOLOGY BASED SEARCH MECHANISM FOR THE EDMS AT CERN

CERN is building its new accelerator, the LHC. Its lifecycle dataflow is stored in the EDMS system. Due to the size of the collection and the diversity of people, organizations and divisions it is difficult to find documents without prior domain knowledge. To overcome this problem, an approach based on a hand-crafted domain specific ontology has been tested in order to improve information retrieval for the LHC Equipment Catalog. Experiments have shown that the use of an ontology improves average precision.
Mediator profiles in tears during the conjunctival response induced by allergic reaction in the nasal mucosa

Background The allergic reaction occurring primarily in the nasal mucosa can induce a secondary conjunctival response of an immediate (SICR), late (SLCR), or delayed (SDYCR) type in some patients with allergic conjunctivitis (AC). Objectives To investigate the concentration changes of histamine, tryptase, eosinophil cationic protein (ECP), eosinophil-derived neurotoxin (EDN), leukotrienes (LTB 4, LTC4, LTE4), myeloperoxidase (MPO), interferon-γ (IFN-γ), and interleukins (IL-2, IL-4, IL-5) in tears during the SICR, SLCR, and SDYCR. Methods In 32 patients with AC, 11 SICR (p<0.01), 13 SLCR (p<0.001), and eight SDYCR (p<0.01) to nasal challenges with allergens (NPTs), the NPTs and 32 control tests with PBS were repeated and supplemented with the determination of these factors in tears. Results The SICRs were associated with significant concentration changes in tears (p<0.05) of histamine, tryptase, ECP, LTC4, and IL-4. The SLCRs were accompanied by significant changes in concentrations of histamine, ECP, LTB4, LTC4, MPO, IL-4, and IL-5. The SDYCRs were associated with significant concentration changes in tears (p<0.05) of LTB4, MPO, IFN-γ, and IL-2. No significant changes in these factors were recorded in tears during the 32 PBS controls (p>0.1) or in the ten control patients (p>0.1). Conclusions These results provide evidence for causal involvement of nasal allergy in some patients with AC, inducing secondary conjunctival response of immediate (SICR), late SLCR, or delayed SDYCR type, associated with different mediator, cytokine, and cellular profiles in the tears, suggesting involvement of different hypersensitivity mechanisms. These results also emphasize the diagnostic value of nasal allergen challenge combined with monitoring of the conjunctival response in some patients with AC.
Effectiveness of bridge V.A.C. dressings in the treatment of diabetic foot ulcers

Objectives: This is a prospective study of the clinical efficacy of the V.A. C. Granufoam Bridge Dressing for the treatment of diabetic foot ulcers. Materials and methods: Five consecutive patients with diabetic foot ulcers were treated with V.A. C. Granufoam Bridge Dressings and studied over a period of 22–48 days. The indications for treatment included diabetic patients with open ray amputation wounds and wounds post-drainage for abscess with exposed deep structures. Clinical outcome was measured in terms of reduction in wound dimensions, presence of wound granulation, microbial clearance, and development of wound complications. Results: Our results showed that with V.A. C. therapy, wound healing occurred in all patients. The number of dressings required ranged from 8 to 10. The baseline average wound size was 23.1 cm2. Wound areas shrunk by 18.4–41.7%. All subjects achieved 100% wound bed granulation with an average length of treatment of 33 days. Microbial clearance was achieved in all cases. All wounds healed by secondary intention in one case and four cases required split-thickness skin grafting. Conclusion: The V.A. C. Granufoam Bridge Dressing is effective in the treatment of diabetic foot ulcers. It promotes reduction of wound area, wound bed granulation, and microbial clearance. By allowing placement of the suction pad outside the foot, it allowed patients to wear protective shoes and to walk non-weight bearing with crutches during V.A. C. therapy.
A 1V, −26dBm sensitive auto configurable mixed converter mode RF energy harvesting with wide input range

A maximum power point tracking DC-DC boost converter and reconfigurable rectifier to harvest energy from ambient RF source in an auto-configurable mixed converter mode is presented. A reconfigurable rectifier with adjustable rectifier stages in the high input power range(-16dBm to -8dBm) and a boost converter with adaptive control in the low input power level range(-26dBm to -17dBm) to maximize the efficiency is proposed. The system is designed at UHF band(900MHz) to drive a load with 1V and shows a peak efficiency of 62.8% at -20dBm and 78.2% at -12dBm and it is implemented using UMC 0. 18μm CMOS technology.
A spectral power analysis of driving behavior changes during the transition from nondistraction to distraction

ABSTRACT Objective: This article investigated and compared frequency domain and time domain characteristics of drivers' behaviors before and after the start of distracted driving. Method: Data from an existing naturalistic driving study were used. Fast Fourier transform (FFT) was applied for the frequency domain analysis to explore drivers' behavior pattern changes between nondistracted (prestarting of visual–manual task) and distracted (poststarting of visual–manual task) driving periods. Average relative spectral power in a low frequency range (0–0.5 Hz) and the standard deviation in a 10-s time window of vehicle control variables (i.e., lane offset, yaw rate, and acceleration) were calculated and further compared. Sensitivity analyses were also applied to examine the reliability of the time and frequency domain analyses. Results: Results of the mixed model analyses from the time and frequency domain analyses all showed significant degradation in lateral control performance after engaging in visual–manual tasks while driving. Results of the sensitivity analyses suggested that the frequency domain analysis was less sensitive to the frequency bandwidth, whereas the time domain analysis was more sensitive to the time intervals selected for variation calculations. Different time interval selections can result in significantly different standard deviation values, whereas average spectral power analysis on yaw rate in both low and high frequency bandwidths showed consistent results, that higher variation values were observed during distracted driving when compared to nondistracted driving. Conclusions: This study suggests that driver state detection needs to consider the behavior changes during the prestarting periods, instead of only focusing on periods with physical presence of distraction, such as cell phone use. Lateral control measures can be a better indicator of distraction detection than longitudinal controls. In addition, frequency domain analyses proved to be a more robust and consistent method in assessing driving performance compared to time domain analyses.
Multifocal electroretinogram in normal emmetropic subjects: Correlation with optical coherence tomography

Aim of the Study: To establish the normative database for multifocal electroretinogram (mfERG) parameters in a normal emmetropic population. To correlate the data so obtained with the central macular thickness obtained using the optical coherence tomography (OCT) scan. Materials and Methods: mfERG data were obtained from 222 eyes of 111 emmetropic subjects. The amplitude (nv/deg2) and implicit times (ms) of the first-order kernel mfERG responses (N1, P1, and N2 waves) were obtained and grouped into five rings (Ring 1: Central 2°, Ring 2: 2–5°, Ring 3: 5–10°, Ring 4: 10–15°, Ring 5: >15°). The central macular thickness (CMT) was obtained using the macular thickness scan protocol of the OCT. Results: The mfERG data obtained were used to create a normative database. The amplitudes of the mfERG waves were maximum in the fovea and progressively decreased with increasing eccentricity (P = 0.0001). The latencies of the P1 and N2 waves were longest in the central ring and progressively shortened with eccentricity (P = 0.0001). No statistically significant correlations were observed between central ring 1 parameters and the CMT. Conclusion: This study establishes normative database for mfERG parameters in an emmetropic population. No statistically significant correlation was noted between CMT and mfERG parameters.
Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition

Cell therapy with bone marrow multipotential stromal cells (MSCs) represents a promising approach to promote wound healing and tissue regeneration. MSCs expanded in vitro lose early progenitors with differentiation and therapeutic potentials under normoxic condition, whereas hypoxic condition promotes MSC self‐renewal through preserving colony forming early progenitors and maintaining undifferentiated phenotypes. Hypoxia inducible factor (HIF) pathway is a crucial signaling pathway activated in hypoxic condition. We evaluated the roles of HIFs in MSC differentiation, colony formation, and paracrine activity under hypoxic condition. Hypoxic condition reversibly decreased osteogenic and adipogenic differentiation. Decrease of osteogenic differentiation depended on HIF pathway; whereas decrease of adipogenic differentiation depended on the activation of unfolded protein response (UPR), but not HIFs. Hypoxia‐mediated increase of MSC colony formation was not HIF‐dependent also. Hypoxic exposure increased secretion of VEGF, HGF, and basic FGF in a HIF‐dependent manner. These findings suggest that HIF has a limited, but pivotal role in enhancing MSC self‐renewal and growth factor secretions under hypoxic condition. J. Cell. Biochem. 112: 804–817, 2011. © 2010 Wiley‐Liss, Inc.
Pre‐operative anaemia

Pre‐operative anaemia is a relatively common finding, affecting a third of patients undergoing elective surgery. Traditionally associated with chronic disease, management has historically focused on the use of blood transfusion as a solution for anaemia in the peri‐operative period. Data from large series now suggest that anaemia is an independent risk associated with poor outcome in both cardiac and non‐cardiac surgery. Furthermore, blood transfusion does not appear to ameliorate this risk, and in fact may increase the risk of postoperative complications and hospital length of stay. Consequently, there is a need to identify, diagnose and manage pre‐operative anaemia to reduce surgical risk. Discoveries in the pathways of iron metabolism have found that chronic disease can cause a state of functional iron deficiency leading to anaemia. The key iron regulatory protein hepcidin, activated in response to inflammation, inhibits absorption of iron from the gastrointestinal tract and further reduces bioavailability of iron stores for red cell production. Consequently, although iron stores (predominantly ferritin) may be normal, the transport of iron either from the gastrointestinal tract or iron stores to the bone marrow is inhibited, leading to a state of ‘functional’ iron deficiency and subsequent anaemia. Since absorption from the gastrointestinal tract is blocked, increasing oral iron intake is ineffective, and studies are now looking at the role of intravenous iron to treat anaemia in the surgical setting. In this article, we review the incidence and impact of anaemia on the pre‐operative patient. We explain how anaemia may be caused by functional iron deficiency, and how iron deficiency anaemia may be diagnosed and treated.
Symbolism, the universal language

Want to get experience? Want to get any ideas to create new things in your life? Read symbolism the universal language now! By reading this book as soon as possible, you can renew the situation to get the inspirations. Yeah, this way will lead you to always think more and more. In this case, this book will be always right for you. When you can observe more about the book, you will know why you need this.
Conditions of Learning

Robert Gagné was an American educational psychologist who's ideas of conditions of learning and instructional design implications were first introduced in 1965. Gagné assumed that there are different types of learning outcomes, each of which is best achieved through its specific instructional design, but also that there is a set of steps required in every learning environment (sometimes also known as the Gagné Assumption).
Impacts of Parents' Divorce on Chinese Children

Abstract The study examined the impact of parents' divorce on Chinese children's well-being. A Chinese theoretical model was tested using Structural Equation Modeling. The sample consisted of 940 Chinese children aged 6–16. The well-being of children from divorced families was compared with that of two-parent and widowed families. The results showed that children's academic performance mediated the negative impact of divorce on children's well-being. The societal discriminating attitude towards divorce and single-parent families had a strong negative effect on the children's well-being. Parenting skills of the custodial parent had more influence on the children's well-being than the marital conflicts prior to the divorce. Supports from the extended families counterbalanced some negative effects associated with divorce.