Miracle-dz/UniFAR-FTUs huggingface dataset:
Banks' Financial Distress, Lending Supply and Consumption Expenditure

The paper employs a unique identification strategy that links survey data on household consumption expenditure to bank level data in order to estimate the effects of bank financial distress on consumer credit and consumption expenditures. Specifically, we show that households whose banks were more exposed to funding shocks report significantly lower levels of non-mortgage liabilities compared to a matched sample of households. The reduced access to credit, however, does not result in lower levels of consumption. Instead, we show that households compensate by drawing down liquid assets. Only households without the ability to draw on liquid assets reduce consumption. The results are consistent with consumption smoothing in the face of a temporary adverse lending supply shock. The results contrast with recent evidence on the real effects of finance on firms' investment, where even temporary adverse credit supply shocks are associated with significant real effects.
3′,4′,5′,5,7-Pentamethoxyflavone Sensitizes Cisplatin-Resistant A549 Cells to Cisplatin by Inhibition of Nrf2 Pathway

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important redox-sensitive transcription factor that regulates the expression of several cytoprotective genes. More recently, genetic analyses of human tumors have indicated that Nrf2 may cause resistance to chemotherapy. In this study, we found that the expression levels of Nrf2 and its target genes GCLC, HO-1, NQO1 were significantly higher in cisplatin-resistant A549 (A549/CDDP) cells than those in A549 cells, and this resistance was partially reversed by Nrf2 siRNA. 3′,4′,5′,5,7-Pentamethoxyflavone (PMF), a natural flavonoid extracted from Rutaceae plants, sensitized A549/CDDP to CDDP and substantially induced apoptosis compared with that of CDDP alone treated group, and this reversal effect decreased when Nrf2 was downregulated by siRNA. Mechanistically, PMF reduced Nrf2 expression leading to a reduction of Nrf2 downstream genes, and in contrast, this effect was decreased by blocking Nrf2 with siRNA. Taken together, these results demonstrated that PMF could be used as an effective adjuvant sensitizer to increase the efficacy of chemotherapeutic drugs by downregulating Nrf2 signaling pathway.
Refining Word Alignment with Discriminative Training

The quality of statistical machine translation systems depends on the quality of the word alignments that are computed during the translation model training phase. IBM alignment models, as implemented in the GIZA++ toolkit, constitute the de facto standard for performing these computations. The resulting alignments and translation models are however very noisy, and several authors have tried to improve them. In this work, we propose a simple and effective approach, which considers alignment as a series of independent binary classification problems in the alignment matrix. Through extensive feature engineering and the use of stacking techniques, we were able to obtain alignments much closer to manually defined references than those obtained by the IBM models. These alignments also yield better translation models, delivering improved performance in a large scale Arabic to English translation task.
The English Language Learning inside the Escuela Activa Urbana Model in a Public School: A Study of Sixth Graders

This study reports the findings of research dealing with sixth-graders’ perceptions of English language learning and the impact of active learning approaches in a public school in Manizales, Colombia. Participants in the research were involved in lessons planned according to the principles of task-based learning and active learning, inside the Escuela Activa Urbana model implemented by some private and public institutions in this city. The findings reported a positive impact of the model on the language learning process which was reflected in the increase of students’ participation, language production, and class interaction. Key words: English as a foreign language, task-based learning, active learning, teamwork Este estudio reporta los hallazgos de una investigacion sobre las percepciones del aprendizaje de la lengua inglesa por parte de alumnos de sexto grado y el impacto de enfoques de aprendizaje activo en un colegio publico en Manizales, Colombia. Los participantes en la investigacion tomaron parte en clases planeadas de acuerdo con los principios del aprendizaje basado en tareas y de las metodologias activas en el marco del modelo Escuela Activa Urbana implementado por algunas instituciones publicas y privadas de la ciudad. Los hallazgos reportan un impacto positivo del modelo en el proceso de aprendizaje de la lengua el cual se refleja en el incremento de la participacion, la produccion linguistica y la interaccion de los estudiantes. Palabras clave: Ingles como lengua extranjera, aprendizaje basado en tareas, aprendizaje activo, trabajo en equipo
An Arts Intervention for Older Adults Living in Subsidized Retirement Homes

ABSTRACT A theatrically based intervention was given to 122 older adults who took lessons twice a week for 4 weeks. The training consisted of multi-modal activities (cognitive–affective–physiological) typically employed in college acting classes. Comparison groups consisted of no-treatment controls and participants instructed in a different performing art, singing. Assessment of effectiveness was performed using a battery of 11 cognitive/affective test measures that included word recall, prose comprehension/recall, word generation, digit-span ability, and problem-solving. It was found that the acting group improved significantly from pretest to posttest over both other groups. Digit-span was the only measure that failed to improve. The gains were achieved despite the fact that no aspects of the intervention supplied specific training or practice on the test measures. Previous versions of the intervention with community-dwelling adults had produced similar findings but the current participants were older, less well-educated, and lived in subsidized, primarily low-income, retirement homes.
Real-Time Anomaly Detection for Streaming Analytics

Much of the worlds data is streaming, time-series data, where anomalies give significant information in critical situations. Yet detecting anomalies in streaming data is a difficult task, requiring detectors to process data in real-time, and learn while simultaneously making predictions. We present a novel anomaly detection technique based on an on-line sequence memory algorithm called Hierarchical Temporal Memory (HTM). We show results from a live application that detects anomalies in financial metrics in real-time. We also test the algorithm on NAB, a published benchmark for real-time anomaly detection, where our algorithm achieves best-in-class results.
Updating Quasi-Newton Matrices With Limited Storage

We study how to use the BFGS quasi-Newton matrices to precondition minimization methods for problems where the storage is critical. We give an update formula which generates matrices using information from the last m iterations, where m is any number supplied by the user. The quasi-Newton matrix is updated at every iteration by dropping the oldest information and replacing it by the newest informa- tion. It is shown that the matrices generated have some desirable properties. The resulting algorithms are tested numerically and compared with several well- known methods. 1. Introduction. For the problem of minimizing an unconstrained function / of n variables, quasi-Newton methods are widely employed (4). They construct a se- quence of matrices which in some way approximate the hessian of /(or its inverse). These matrices are symmetric; therefore, it is necessary to have n(n + l)/2 storage locations for each one. For large dimensional problems it will not be possible to re- tain the matrices in the high speed storage of a computer, and one has to resort to other kinds of algorithms. For example, one could use the methods (Toint (15), Shanno (12)) which preserve the sparsity structure of the hessian, or conjugate gradient methods (CG) which only have to store 3 or 4 vectors. Recently, some CG algorithms have been developed which use a variable amount of storage and which do not require knowledge about the sparsity structure of the problem (2), (7), (8). A disadvantage of these methods is that after a certain number of iterations the quasi-Newton matrix is discarded, and the algorithm is restarted using an initial matrix (usually a diagonal matrix). We describe an algorithm which uses a limited amount of storage and where the quasi-Newton matrix is updated continuously. At every step the oldest information contained in the matrix is discarded and replaced by new one. In this way we hope to have a more up to date model of our function. We will concentrate on the BFGS method since it is considered to be the most efficient. We believe that similar algo- rithms cannot be developed for the other members of the Broyden 0-class (1). Let / be the function to be nnnimized, g its gradient and h its hessian. We define
Work-Related Musculoskeletal Symptoms and Job Factors Among Large-Herd Dairy Milkers

ABSTRACT Dairy production in the United States is moving towards large-herd milking operations, resulting in an increase in task specialization and work demands. The objective of this project was to provide preliminary evidence of the association of a number of specific job conditions that commonly characterize large-herd parlor milking operations with work-related musculoskeletal symptoms (MSS). A modified version of the Standardized Nordic Questionnaire was administered to assess MSS prevalence among 450 US large-herd parlor workers. Worker demographics and MSS prevalences were generated. Prevalence ratios were also generated to determine associations of a number of specific job conditions that commonly characterize large-herd parlor milking operations with work-related MSS. Work-related MSS are prevalent among large-herd parlor workers, since nearly 80% report 12-month prevalences of one or more symptoms, which are primarily located in the upper extremities, specifically shoulders and wrist/hand. Specific large-herd milking parlor job conditions are associated with MSS in multiple body regions, including performing the same task repeatedly, insufficient rest breaks, working when injured, static postures, adverse environmental conditions, and reaching overhead. These findings support the need for administrative and engineering solutions aimed at reducing exposure to job risk factors for work-related MSS among large-herd parlor workers.
High-Performance Transaction Processing in SAP HANA

Modern enterprise applications are currently undergoing a complete paradigm shift away from traditional transactional processing to combined analytical and transactional processing. This challenge of combining two opposing query types in a single database management system results in additional requirements for transaction management as well. In this paper, we discuss our approach to achieve high throughput for transactional query processing while allowing concurrent analytical queries. We present our approach to distributed snapshot isolation and optimized two-phase commit protocols
Contingency, coherence and conceptualism: reflections on the encounter between 'critique' and 'the philosophy of the criminal law'

Aristotle himself has said , speaking of the laws of his own country, that jurisprudence or the knowledge of those laws is the principal and most perfect branch of ethics. William Blackstone, Commentaries on the Laws of England (1765–9), Volume 1, p. 27 Human life and philosophical explanations of it move in different planes till the explanation has become so complete as not to interfere with the thing to be explained. When they coincide, they cannot affect each other. James Fitzjames Stephen, A History of the Criminal Law of England (1883), Volume II, p. 84 [T]he degree of systematization of a discipline is the prime index of the state of knowledge of its subject matter. Jerome Hall, General Principles of Criminal Law (1960), p. 12 Each of these contrasting reflections expresses a different view of legal theory. In this chapter, I consider the relationship between two particular approaches to criminal law theory: ‘critique’ and ‘the philosophy of criminal law. ’ Whilst the title of my chapter presupposes an opposition between the two, it is in fact one of my main purposes to question that opposition. It is, of course, an opposition which bears some real relationship with the positions held by protagonists in the debate canvassed by Antony Duff in his introduction to this collection. In recent years, a number of British and American writers working within a ‘critical’ tradition have questioned the basis of ‘philosophical’ theories of criminal law which emphasise and seek to elaborate upon its ‘principled’ nature.
Control of Cognitive Processes: Attention and Performance XVIII

One of the most challenging problems facing cognitive psychology and cognitive neuroscience is to explain how mental processes are voluntarily controlled, allowing the computational resources of the brain to be selected flexibly and deployed to achieve changing goals. The eighteenth of the celebrated international symposia on Attention and Performance focused on this problem, seeking to banish or at least deconstruct the "homunculus": that conveniently intelligent but opaque agent still lurking within many theories, under the guise of a central executive or supervisory attentional system assumed to direct processes that are not "automatic. " The thirty-two contributions discuss evidence from psychological experiments with healthy and brain-damaged subjects, functional imaging, electrophysiology, and computational modeling. Four sections focus on specific forms of control: of visual attention, of perception-action coupling, of task-switching and dual-task performance, and of multistep tasks. The other three sections extend the interdisciplinary approach, with chapters on the neural substrate of control, studies of control disorders, and computational simulations. The progress achieved in fractionating, localizing, and modeling control functions, and in understanding the interaction between stimulus-driven and voluntary control, takes research on control in the mind/brain to a new level of sophistication.
Students’ Critical Consciousness Through Critical Literacy Awareness

To think critically is undeniably one of the major elements of “first class human capital” in a knowledge economy. It is most regrettable that Malaysian students, even at the tertiary level, tend to be uncritical due to socialisation processes in the educational and sociocultural environment. Responding to this identified need to raise the critical consciousness of students, this paper examines how a Higher Education teacher challenged her postgraduate students to be critical learners through the use of CLA (Critical literacy awareness) strategies in her Language and Literacy course. The paper suggests that the use of CLA strategies has increased student engagement and strengthened student voices. This paper concludes by proposing that CLA should be included in pedagogical practices in Higher Education given that active participation in knowledge economies is the vision of the Malaysian Higher Education Action Plan (MoHE 2007a, b).
A Computationally Efficient Method for Determining the Size and Location of Myocardial Ischemia

The purpose of this paper is to introduce a new method for solving the inverse problem of locating ischemic regions in the heart. The electrical activity in the human heart is modeled by the bidomain equations, which can be expanded to compute the potentials on the body surface. The associated inverse problem is to use ECG recordings to gain information about ischemias. We propose an algorithm for doing this, combining the level set method with a simpler minimization problem. Instead of trying to determine the shape, as in the level set method, we simply make the approximation that the ischemia is spherical. The effects of ischemia on the electrical attributes of heart tissue are examined. The new method is tested with computer simulations on synthetic body surface potential maps (BSPMs) in a realistic geometry, using realistic values for the parameters. It is shown to be, in some respects, superior to the level set approach and may be a step toward a practical algorithm useful in medical diagnostics.
Politicisation, Depoliticisation and Anti-Politics: Towards a Multilevel Research Agenda

The concepts of ‘politicisation’ and ‘depoliticisation’ have become increasingly used by political scientists over the last decade, in light of the presumed ‘triumph’ of neoliberal ideology in the 1990s, and its subsequent challenge (‘re-politicisation’) by the 2008 ﬁnancial crisis. Debate has emerged in the literature, however, over what conceptual strategy is best for critically analysing depoliticisation – ‘broad’ or ‘narrow’. This article argues for attempting to ﬁnd common ground among ‘competing’ deﬁnitions, by viewing politicisation and depoliticisation as ‘multilevel’ concepts, with theoretical, analytical and empirical purchase. The uniting theme, it is argued, is a critical analysis of the dynamics of neoliberalism as a paradigm of political thought, and how that paradigm allegedly leads to the rise of ‘anti-politics’. Thinking about (de)politicisation in this way helps avoid facile conceptual reinvention and stimulates a coherent yet pluralistic research agenda focused on translating insights and criticism across macro, meso and micro levels.
Incidence and risk factors of suicide reattempts within 1 year after psychiatric hospital discharge in mood disorder patients

Background The incidence and risk factors of suicide reattempts within 1 year after psychiatric hospital discharge in mood disorder patients remain uninvestigated in Thailand. Objective To determine incidence and risk factors of suicide reattempts within 1 year after psychiatric hospital discharge in mood disorder patients. Methods A retrospective cohort study was conducted by reviewing medical charts at Suanprung Psychiatric Hospital, Chiang Mai, Thailand. Mood disorder patients, diagnosed with the International Statistical Classification of Diseases and Related Health Problems 10th Revision codes F31.x, F32.x, and F33.x, who were admitted owing to suicide attempts between October 2006 and May 2009 were eligible. The influence of sociodemographic and clinical risk factors on suicide reattempts was investigated using Cox’s proportional-hazards regression analysis. Results Of 235 eligible mood disorder patients, 36 (15.3%) reattempted suicide (median 109.5 days, range 1–322), seven (3.0%) completed suicide (median 90 days, range 5–185), and 192 (84.2%) neither reattempted nor completed suicide during follow-up. Of all nonfatal suicide reattempts, 14 patients (38.9%) did so within 90 days. Among suicide completers, one (14.3%) did so 5 days after discharge, and four (57.1%) did so within 90 days. The following three risk factors explained 73.3% of the probability of suicide reattempts: over two previous suicide attempts before the index admission (adjusted hazard ratio [HR] 2.48; 95% confidence interval [CI] 1.07–5.76), being concomitantly prescribed typical and atypical antipsychotics (adjusted HR 4.79; 95% CI 1.39–16.52) and antidepressants, and taking a selective serotonin reuptake inhibitor alone (adjusted HR 5.08; 95% CI 1.14–22.75) or concomitantly with norepinephrine and/or serotonin reuptake inhibitors (adjusted HR 6.18; 95% CI 1.13–33.65). Conclusion Approximately 40% of suicide reattempts in mood disorder patients occurred within 90 days after psychiatric hospital discharge. For mood disorders and when there have been over two previous suicide attempts, prescribed antipsychotics or antidepressants may help predict suicide reattempts.
An Abstract Argumentation Framework with Varied-Strength Attacks

In classical abstract argumentation, arguments interact with each other through a single abstract notion of attack. However, several concrete forms of argument conflict are present in the literature, all of them of different nature and strength for a particular context. In this work we define an argumentation framework equipped with a set of abstract attack relations of varied strength. Using this framework, semantic notions dealing with the relative difference of strength are introduced. The focus is put on argument defense, and the study of admissible sets according to the quality of defenders.
Muscle and Tendon Adaptation in Adolescence: Elite Volleyball Athletes Compared to Untrained Boys and Girls

Though the plasticity of human tendons is well explored in adults, it is still unknown how superimposed mechanical loading by means of athletic training affects the properties of tendons during maturation. Due to the increased responsiveness of muscle to mechanical loading, adolescence is an important phase to investigate the effects of training on the mechanical properties of tendons. Hence, in the present study we compared vastus lateralis (VL) architecture, muscle strength of the knee extensor muscles and patellar tendon mechanical properties of male and female adolescent elite athletes to untrained boys and girls. Twenty-one adolescent volleyball athletes (A; 16.7 ± 1 years; 12 boys, 9 girls) and 24 similar-aged controls (C; 16.7 ± 1 years; 12 boys and girls, respectively) performed maximum isometric contractions on a dynamometer for the assessment of muscle strength and, by integrating ultrasound imaging, patellar tendon mechanical properties. Respective joint moments were calculated using an inverse dynamics approach and an electromyography-based estimation of antagonistic contribution. Additionally, the VL pennation angle, fascicle length and muscle-thickness were determined in the inactive state by means of ultrasound. Adolescent athletes produced significantly greater knee extension moments (normalized to body mass) compared to controls (A: 4.23 ± 0.80 Nm/kg, C: 3.57 ± 0.67 Nm/kg; p = 0.004), and showed greater VL thickness and pennation angle (+38% and +27%; p < 0.001). Tendon stiffness (normalized to rest length) was also significantly higher in athletes (A: 86.0 ± 27.1 kN/strain, C: 70.2 ± 18.8 kN/strain; p = 0.04), yet less pronounced compared to tendon force (A: 5785 ± 1146 N, C: 4335 ± 1015 N; p < 0.001), which resulted in higher levels of tendon strain during maximum contractions in athletes (A: 8.0 ± 1.9%, C: 6.4 ± 1.8%; p = 0.008). We conclude that athletic volleyball training provides a more efficient stimulus for muscle compared to tendon adaptation, which results in an increased demand placed upon the tendon by the working muscle in adolescent volleyball athletes. Besides implications for sport performance, these findings might have important consequences for the risk of tendon overuse injury.