Miracle-dz/UniFAR-FTUs huggingface dataset:
Generic Model of SH-LED for Mid-infrared (2-5µm) Applications

In this paper, we present a physics based model of a P+ -InAs0.36Sb0. 20P0.44/ n0 -InAs/n -InAs single heterostructure light emitting diode (SH-LED) suitable for use as source in gas detection and futuristic optical fiber communication systems in the mid-infrared spectral region at 300 K. The model takes into account all dominating radiative and non-radiative recombination processes, interfacial recombination and self-absorption in the active layer of the SH-LED structure. The effect of various recombination mechanisms on the quantum efficiency, modulation bandwidth and output power of the LED has been evaluated. The proposed SH- LED has been studied for its utility in mid-infrared optical fiber communication by considering the modulation bandwidth and its variation with active layer width of the SH-LED structure. The I-V characteristic of the SH-LED has been evaluated and cut-in voltage found to be 0.26 V. The output power of the SH-LED has been computed as a function of bias current and it is found to be in good agreement with the reported experimental results.
Chlamydia trachomatis Infection In Women Attending Urban Midwestern Family Planning and Community Health Clinics: Risk Factors, Selective Screening, and Evaluation of Non‐culture Techniques

To determine prevalence and risk factors for endocervical Chlamydia trachomatis infection in an urban midwestern population and to evaluate two non-culture direct tests for C. trachomatis, we studied 849 women attending two family planning clinics and a community health clinic in Milwaukee, Wisconsin. Adequate endocervical specimens were obtained from 751 women for chlamydial isolation in tissue culture and antigen tests using direct fluorescence (DFA) and enzyme immunoassay (EIA); 93 (12.4%) patients had cultures positive for C. trachomatis. Compared to culture, the DFA test had a 77.4% sensitivity, 96.8% specificity, and a predictive value positive (PVP) of 77%. For the EIA, these values were 83.9%, 97.0%, and 80%, respectively. No single historical, clinical, or laboratory variable, including the previously described cervicitis index and specific cytologic findings on Pap smear, had sufficient predictive value to be used as the only criterion for selective screening in this population. Criteria for selective screening were proposed that would result in screening 43% of patients and would identify 71% of infections. PVP of both non-culture tests was 89% in persons identified by these criteria to be at increased risk of C. trachomatis infection.
Ghrelin and Metabolic Surgery

Metabolic surgery is the most effective treatment for morbid obesity. Ghrelin has been implicated to play a role in the success of these procedures. Furthermore, these operations have been used to study the gut-brain axis. This article explores this interaction, reviewing the available data on changes in ghrelin levels after different surgical procedures.
A 3.2 V –15 dBm Adaptive Threshold-Voltage Compensated RF Energy Harvester in 130 nm CMOS

This paper presents an adaptive RF-DC power converter designed to efficiently convert RF signals to DC voltages utilizing auxiliary transistors to control the threshold voltage of the transistors in the main rectifier chain dynamically. The proposed circuit passively reduces the threshold voltage of the forward-biased transistors to increase the harvested power and the output voltage and increases the threshold voltage of the reverse-biased transistors to reduce the leakage current to prevent the loss of previously stored energy. A 12-stage adaptive threshold-compensated rectifier is designed and implemented in IBM's 0.13 μm CMOS technology. The proposed rectifier exhibits measured maximum power conversion efficiency (PCE) of 32% at -15 dBm (32 μW) of input power while delivering 3.2 V to a 1 M Ω load. At a remarkably low input power of -20.5 dBm (8.9 μW) for a 1 M Ω load, the rectifier produces an output voltage of 1 V.
Glutamate accelerates RPE cell proliferation through ERK1/2 activation via distinct receptor‐specific mechanisms

The proliferation and migration of Retinal Pigment Epithelium cells resulting from an epithelial‐mesenchymal transition plays a key role in proliferative vitreoretinopathy, which leads to retinal detachment and the loss of vision. In neurons, glutamate has been shown to activate the Ras/Raf/MEK/ERK cascade, which participates in the regulation of proliferation, differentiation, and survival processes. Although glutamate‐stimulation and the activation of ERK1/2 by different stimuli have been shown to promote RPE cell proliferation, the signaling pathway(s) linking these effects has not been established. We analyzed the molecular mechanisms leading to glutamate‐induced proliferation by determining ERK1/2 and CREB phoshporylation in chick RPE cells in primary culture and the human‐derived RPE cell line ARPE‐19. This study shows for the first time, that glutamate promotes RPE cell proliferation by activating two distinct signaling pathways linked to selective glutamate receptor subtypes. Results demonstrate that glutamate stimulates RPE cell proliferation as well as ERK and CREB phosphorylation. These effects were mimicked by the mGluR agonist ACPD and by NMDA, and were prevented by the respective receptor inhibitors MCPG and MK‐801, indicating a cause‐effect relationship between these processes. Whereas mGluR promoted proliferation by activating the MEK/ERK/CREB cascade, NMDA stimulated proliferation through the MEK‐independent activation of Ca2+/calmodulin‐dependent kinases. The blockage of both signaling pathways to proliferation by KN‐62 suggests the involvement of CaMKs in the control of glutamate‐induced proliferation at a common step, downstream of CREB, possibly the regulation of cell cycle progression. Based on these findings, the participation of glutamate in the development of PVR can be considered. J. Cell. Biochem. 104: 377–390, 2008. © 2007 Wiley‐Liss, Inc.
Darwinism for the Genomic Age: Connecting Mutation to Diversification

A growing body of evidence suggests that rates of diversification of biological lineages are correlated with differences in genome-wide mutation rate. Given that most research into differential patterns of diversification rate have focused on species traits or ecological parameters, a connection to the biochemical processes of genome change is an unexpected observation. While the empirical evidence for a significant association between mutation rate and diversification rate is mounting, there has been less effort in explaining the factors that mediate this connection between genetic change and species richness. Here we draw together empirical studies and theoretical concepts that may help to build links in the explanatory chain that connects mutation to diversification. First we consider the way that mutation rates vary between species. We then explore how differences in mutation rates have flow-through effects to the rate at which populations acquire substitutions, which in turn influences the speed at which populations become reproductively isolated from each other due to the acquisition of genomic incompatibilities. Since diversification rate is commonly measured from phylogenetic analyses, we propose a conceptual approach for relating events of reproductive isolation to bifurcations on molecular phylogenies. As we examine each of these relationships, we consider theoretical models that might shine a light on the observed association between rate of molecular evolution and diversification rate, and critically evaluate the empirical evidence for these links, focusing on phylogenetic comparative studies. Finally, we ask whether we are getting closer to a real understanding of the way that the processes of molecular evolution connect to the observable patterns of diversification.
Visual perception from the perspective of a representational, non-reductionistic, level-dependent account of perception and conscious awareness

This article proposes a new model to interpret seemingly conflicting evidence concerning the correlation of consciousness and neural processes. Based on an analysis of research of blindsight and subliminal perception, the reorganization of elementary functions and consciousness framework suggests that mental representations consist of functions at several different levels of analysis, including truly localized perceptual elementary functions and perceptual algorithmic modules, which are interconnections of the elementary functions. We suggest that conscious content relates to the ‘top level’ of analysis in a ‘situational algorithmic strategy’ that reflects the general state of an individual. We argue that conscious experience is intrinsically related to representations that are available to guide behaviour. From this perspective, we find that blindsight and subliminal perception can be explained partly by too coarse-grained methodology, and partly by top-down enhancing of representations that normally would not be relevant to action.
Generating entanglement with linear optics

Entanglement is the basic building block of linear optical quantum computation, and as such understanding how to generate it in detail is of great importance for optical architectures. We prove that Bell states cannot be generated using only three photons in the dual-rail encoding, and give strong numerical evidence for the optimality of the existing four photon schemes. In a setup with a single photon in each input mode, we find a fundamental limit on the possible entanglement between a single mode Alice and arbitrary Bob. We investigate and compare other setups aimed at characterizing entanglement in settings more general than dual-rail encoding. The results draw attention to the trade-off between the entanglement a state has and the probability of postselecting that state, which can give surprising constant bounds on entanglement even with increasing numbers of photons.
Gender impact on the correlation between thyroid function and serum lipids in patients with differentiated thyroid cancer

The present study aimed to explore the association between thyroid stimulating hormone (TSH) and serum lipids in patients with differentiated thyroid cancer (DTC), with a focus on the risk of hyperlipidemia between different genders. The study included 352 DTC patients who were ready to receive I-131 therapy as well as 352 matched normal controls. In the DTC group, 157 patients were monitored for TSH and lipid parameters prior to and after 1 month of thyroxine therapy. Results were analyzed using t-tests, Pearson bivariate correlation and binary logistic regression analyses. All participants were divided into 3 subgroups according to TSH levels: Subgroup 1 (normal TSH level), subgroup 2 (TSH between 5 and 30 µIU/ml), and subgroup 3 (TSH >30 µIU/ml). Serum total cholesterol (TC), triglycerides (TG), and low-density lipoprotein-cholesterol (LDL-C) levels were significantly higher in the DTC group than in the control group. The levels of these parameters decreased after thyroxine therapy and significant positive correlations were observed between TSH and TC, and TG and LDL-C in both genders. Binary logistic regression demonstrated that female DTC patients had higher risks of developing hyperlipidemia than male patients, and these risks increased when TSH increased. For example, the odds ratios (ORs) of high TC in subgroup 2 were 3.30 in males and 4.60 in females, respectively. However, in subgroup 3, the ORs were 9.40 in males and 13.12 in females, respectively. The results of the present study showed that after thyroidectomy, the risk of dyslipidemia markedly increased in DTC patients. More importantly, female patients had a higher risk than male patients.
The development of cholesteatoma in association with congenital abnormalities of the ear

Cholesteatoma is a rare complication of congenital atresia of the external auditory meatus and middle ear. Jahrsdoerfer (1978) reviewed the world literature prior to 1975 and identified 20 published cases. The same author has more recently reported six more (Jahrsdoerfer, 1980) and Miyamoto et al. (1984) have published a twenty-seventh case. This paper reports three cases of cholesteatoma in association with variable degrees of congenital atresia of the ear and discusses the pathogenesis and presentation of these lesions.
Dried Fruits: Excellent in Vitro and in Vivo Antioxidants

Objective: The goal of this work is to determine the amount and quality of phenol antioxidants in dried fruits and compare them with the corresponding fresh fruits; to compare the nutrients in fresh and dried fruits; to determine if figs are a source of in vivo antioxidants when eaten. Methods: Commercial samples of dried fruits and fresh fruits were compared in the in vitro studies using a colorimetric method to measure phenolic antioxidants. The quality of the antioxidants was measured by inhibition of lower density lipoprotein oxidation. Ten normal free-living subjects were tested in the human study. Fasting subjects were given 40 g of figs with or without a carbonated beverage and the plasma antioxidant capacity was measured for six hours using the trolox equivalent antioxidant capacity assay. Results: Dates have the highest concentration of polyphenols among the dried fruits. Figs and dried plums have the best nutrient score among the dried fruits, and dates among the fresh fruits. Processing to produce the dried fruit significantly decreases the phenols in the fruits on a dry weight basis. Compared with vitamins C and E, dried fruits have superior quality antioxidants with figs and dried plums being the best. Fig antioxidants can enrich lipoproteins in plasma and protect them from subsequent oxidation. Figs produced a significant increase in plasma antioxidant capacity for 4 hours after consumption, and overcame the oxidative stress of consuming high fructose corn syrup in a carbonated soft drink. Conclusion: Dried fruits and especially figs, are a convenient and superior source of some nutrients, but in the American diet amount to less than 1% of total fruit consumed. Figs are in vivo antioxidants after human consumption. The findings suggest that dried fruits should be a greater part of the diet as they are dense in phenol antioxidants and nutrients, most notably fiber.
Inactivated influenza vaccines. 2. Laboratory indices of protection.

Summary The data from our 1968-69 influenza vaccine field trials are anlaysed and pre-challenge haemagglutinin and neuraminidase serum antibodies are evaluated as indices of protection. Prevention of flu-like disease, fever, confinement to bed, and/or seroconversion to Hong Kong was significantly related to post-vaccine A/Hong Kong/68(H3N2) haemagglutination-inhibition (HI) titres. Prevention of disease was also related, although not significantly statistically in every category, to pre-chaUenge A/Hong Kong/68 neuraminidase inhibition (NI) titres. The trend was the same regardless of whether the origin of the NI antibody was through A/Aichi/68 or A/Japan/62 vaccines or through pre-Hong Kong influenza infections. In summarizing the data using fever as an index of disease, the attack rate (AR) among volunteers without Hong Kong NI or HI antibody was 45%. Presence NI AR 24 %. Those with both NI and HI titres a still 14%. Those and > 1 :
Neighbourhood immigrant concentration effects on migrant and native youth’s educational commitments, an enquiry into personality differences

In the literature examining neighbourhood effects on educational outcomes, the socialisation mechanism is usually investigated by looking at the association between neighbourhood characteristics and educational attainment. The step in between, that adolescents actually internalise educational norms held by residents, is often assumed. We attempt to fill this gap by looking at how the internalisation of educational norms (commitments) is influenced by neighbourhoods’ immigrant concentration. We investigate this process for both migrant and native youth, as both groups might be influenced differently by immigrant concentrations. To test our hypothesis we used longitudinal panel data with five waves (N = 4255), combined with between-within models which control for a large portion of potential selection bias. These models have an advantage over naïve OLS models in that they predict the effect of change in neighbourhood characteristics on change in educational commitment, and therefore offer a more dynamic approach to modelling neighbourhood effects. Our results show that living in neighbourhoods with higher proportions of immigrants increases the educational commitments of migrant youth compared to living in neighbourhoods with lower proportions. Besides, we find that adolescents with a resilient personality experience less influence of the neighbourhood context on educational commitments than do adolescents with non-resilient personalities.
School Attendance is a Pre-Requisite for Student Academic Performance in Universal Secondary Education Schools

The study explored the effects of students’ absenteeism on student academic and school performance in Uganda. The study also assessed the effectiveness of class attendance monitoring tool; the challenges faced by the school administration in dealing with absentee student(s); and established the relationship between students’ absenteeism and academic performance of students. The relevant literature was reviewed to anchor the methodology and the findings. The study adopted descriptive cross-sectional survey design. A combination of stratified and purposive sampling was applied to accommodate the variety of respondents from Serere, Soroti, Kumi and Ngora districts in Teso sub-region; North Eastern Uganda. The study used questionnaires and interview schedules to collect primary data from 349 respondents who participated in the study out of the expected 384 obtained from a target population of 100,000 giving a response rate of 90.89%. The findings shows that the monitoring tools used for students’ attendance are effective (good) and there is a very positive relationship between student attendance and academic performance. The researcher also found that school attendance affects both the students and the school performance. To the students; it leads to poor academic performance, students drop out, graduating half-baked students, poor curriculum coverage and loss of interest in learning whist to the school; it affects the school image, lower the students’ enrollment, transfer of students by parents, wastage of teachers’ and administrators’ time and affects the university/tertiary enrolment. However, the school administration faces challenges of; interruption of lessons, students being hostile/belligerent to teachers, and parents defending their children whilst dealing with absenteeism students. The study also provides the practical and most effective strategies to improve students’ attendance. These staregies include; promoting Zero Tolerance to Students Absenteeism, parental involvement and participation, developing students’ mentoring programmes, improving “rich” student’s programmes, promoting guidance and counseling, promote good communication, reward students with regular attendance, and need to monitor and supervise school attendance. The researcher concludes that, to support students academically in and out of school; administrators, teachers, and families need to have a shared understanding of their children’s learning and work as partners to meet their academic and social-emotional needs.
The true prognosis of resected distal cholangiocarcinoma

Prognosis of distal cholangiocarcinoma (DCC) after pancreaticoduodenectomy (PD) remains poorly assessed. The aims of this study were to describe the oncological results of PD in DCC and to compare its prognosis to pancreatic ductal adenocarcinoma (PDAC).
Hyperglycemia Is a Risk Factor for Early Death and Morbidity in Extremely Low Birth-Weight Infants

OBJECTIVES. The objectives of this study were to determine the prevalence of hyperglycemia in extremely low birth-weight infants and to determine whether hyperglycemia increases the risk of early adverse outcomes (death or intraventricular hemorrhage of grade 3 or 4) and/or affects the length of hospital stay among survivors without intraventricular hemorrhage. METHODS. The charts of all extremely low birth-weight infants (n = 93) admitted to Texas Children's Hospital (Houston, TX) during 2001 were reviewed. The highest daily blood glucose concentrations, highest dopamine infusion rates, highest daily percentage of inspired oxygen, and mean blood sodium concentrations were averaged over the first week of life or before death or occurrence of grade 3 or 4 intraventricular hemorrhage. Among survivors without severe intraventricular hemorrhage, the time ratio for blood glucose concentrations of >150 mg/dL was calculated. RESULTS. More than 50% of the infants had persistent blood glucose concentrations of >150 mg/dL during their first week of life. Early adverse outcomes were associated with the average highest daily blood glucose concentration through interaction with the Clinical Risk Index for Babies score and with the average highest daily percentage of inspired oxygen. The length of hospital stay was associated with the time ratio for blood glucose concentrations of >150 mg/dL through interaction with birth weight and the average highest daily percentage of inspired oxygen. CONCLUSION. These data confirm the high prevalence of hyperglycemia among parenterally fed, extremely low birth-weight infants and show that high blood glucose concentrations increase the risk of early death and grade 3 or 4 intraventricular hemorrhage and the length of hospital stay among survivors without intraventricular hemorrhage, which suggests that prevention and treatment of hyperglycemia may improve the outcomes of extremely low birth-weight infants.
Sacred and secular leadership discourses : interpreting the leadership of evangelical Christian school leaders

The research enquiry for this thesis, from an insider/outsider position, is a deeply held reflection of personal values, convictions and professional experiences stemming from the researcher's life's work in school leadership both in the United States and abroad. The intent of this study is to engage with the sacred discourse of evangelical Christian school leaders and the discourse of the sacred and secular scholarly literature. This is a qualitative study of a constructivist/interpretivist approach where semistructured interviews, with 12 senior school leaders, four in each of three Anglophone countries, inform the data. A more in-depth case study of one school is utilised as a comprehensive illustration of thematic elements revealed through multiple data sources. The preliminary literature for this research was based on the readings of various contemporary theories of leadership and literature around servant-leadership from which the initial research question was framed. As the data analysis advanced, a new framework emerged around attributes of leadership and community building through leadership, making it imperative to accommodate a new set of transformational/relational/ethical literature, taking the story on a completely different journey with a new research question and sub-questions; therefore, leaving behind the initial research question. Two descriptors of leadership became the primary framework for the thesis: the 'sacred' and the 'secular' discourses relating to school leadership. Standing in the doorway, as it were, the researcher took on a role of interpreting and translating one discourse to the other rather than acting solely as observer and interpreter of the data. The findings, the utilisation of two discourses, and the interpretive stance make a positive and original contribution to knowledge and are significant in two ways. First, the participants, speaking through the sacred discourse, express an extension to or linkage with the secular literature, revealing much more overlap between the two discourses than was expected. Second, the secular literature does not capture the sacred discourse; there is an appurtenance — an add-on — a more spiritual dimension, to consider.