Miracle-dz/UniFAR-FTUs huggingface dataset:
THE MID-INFRARED VIEW OF RED SEQUENCE GALAXIES IN ABELL 2218 WITH AKARI

We present the AKARI Infrared Camera (IRC) imaging observation of early-type galaxies (ETGs) in A2218 at z≃ 0.175. Mid-infrared (MIR) emission from ETGs traces circumstellar dust emission from asymptotic giant branch (AGB) stars or/and residual star formation. Including the unique imaging capability at 11 and 15 μm, our AKARI data provide an effective way to investigate MIR properties of ETGs in the cluster environment. Among our flux-limited sample of 22 red sequence ETGs with precise dynamical and line strength measurements (less than 18 mag at 3 μm), we find that at least 41% have MIR-excess emission. The N3 − S11 versus N3 (3 and 11 μm) color–magnitude relation shows the expected blue sequence, but the MIR-excess galaxies add a red wing to the relation especially at the fainter end. A spectral energy distribution analysis reveals that the dust emission from AGB stars is the most likely cause of the MIR excess, with a low level of star formation being the next possible explanation. The MIR-excess galaxies show a wide spread of N3 − S11 colors, implying a significant spread (2–11 Gyr) in the estimated mean ages of stellar populations. We study the environmental dependence of MIR-excess ETGs over an area out to a half virial radius (∼1 Mpc). We find that the MIR-excess ETGs are preferentially located in the outer region. From this evidence, we suggest that the fainter, MIR-excess ETGs have just joined the red sequence, possibly due to the infall and subsequent morphological/spectral transformation induced by the cluster environment.
Service innovation capability: Proposing a new framework

Service organizations face the challenge of offering their customers continuously improved or completely new services and, hence, require service innovations to sustain themselves in the market. We interpret the design and implementation of new or enhanced service offerings as a dynamic capability because the service organization is required to sense impulses for innovation, seize meaningful ways for change, and to finally transform its operational capabilities to the desired state. Accordingly, we propose a new framework which structures service innovation capability into the areas of sensing, seizing, and transformation. We further identify and describe the key activities in all of these three areas based on an analysis of existing literature. With this conceptual paper, we contribute to a better understanding of service innovation capability by proposing a novel framework which is grounded in dynamic capability theory. This framework is beneficial to both practice and academia. It offers an overview of service innovation capability areas and activities against which service organizations can critically reflect their service innovation initiatives. As for academia, it stipulates promising directions for future research.
A deep-trenched capacitor technology for 4 mega bit dynamic RAM

A deep-trenched capacitor technology is one of key processes for realizing 4Mb DRAM(1). Major subjects in this technology are to form a precisely controlled shallow diffusion layer at vertical side walls and to grow high reliable thin gate oxide on the trenched Si surface. In this paper, arsenic doping from As doped SiO2(AsSG) film into the vertical side walls and the rounding oxidation technique in O2ambient including a few percent H2O, have been introduced. These techniques enable us to utilize the high-reliability trenched capacitors featuring large charge storage capability as well as low leakage current for 4Mb DRAM's.
Trochanteric Entry for Femoral Lengthening Nails in Children: Is It Safe?

Background: Antegrade intramedullary (IM) nailing for skeletally immature femur fractures can damage the capital femoral epiphysis blood supply, leading to avascular necrosis (AVN) of the femoral head. Reported AVN rates are 2% for piriformis entry and 1.4% for trochanteric entry. None of previous reports described IM lengthening nails for limb lengthening procedures. We have used self-lengthening telescopic nails with a proximal Herzog bend and standard trochanteric entry for femoral lengthening in children. The purpose of this study is to determine whether trochanteric entry IM lengthening nails can be used safely (no AVN or proximal femoral deformity) in the skeletally immature femur. Methods: A retrospective review was performed between 2004 and 2014 to determine all skeletally immature patients younger than 18 years of age who had a reamed IM lengthening nail inserted through the greater trochanter, with at least 1-year follow-up. Results: Thirty-one femurs were lengthened in 28 patients (17 males and 11 females). The etiology was congenital femoral deficiency (10), achondroplasia (6), post-traumatic (5), hemihypertrophy (3), Ollier disease (2), and miscellaneous (5). An attending surgeon was present for all procedures. Mean age at time of surgery was 12.9 years (range, 7 to 17 y). Mean follow-up was 3.5 years (range, 1.4 to 9 y). The average amount of lengthening was 5.4 cm (range, 3 to 6.7 cm). Twenty-four nails were 10.7 mm in diameter. Seven nails were 12.5 mm in diameter. Intramedullary skeletal kinetic distractor was used in 18 femurs and PRECICE in 13 femurs. Ten segments (7 intramedullary skeletal kinetic distractor; 3 PRECICE) experienced 13 complications. None of the patients developed AVN or proximal femoral deformity. Conclusions: IM lengthening nails inserted through the greater trochanter may be utilized in skeletally immature patients without increased risk of AVN of the femoral head or proximal femoral deformity. Larger trials would be helpful to confirm our hypothesis. We recommend careful surgical technique with liberal use of the image intensifier to avoid trauma to the femoral head blood supply. Level of Evidence: Level IV—therapeutic.
Treatment effect of memantine on survival in dementia with Lewy bodies and Parkinson's disease with dementia: a prospective study

Objective To investigate the effect on survival of treatment with memantine in patients with dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD). Methods 75 patients with DLB and PDD were included in a prospective double-blinded randomised placebo-controlled trial (RCT) of memantine, of whom long-term follow-up was available for 42. Treatment response was recorded 24 weeks from baseline and measured by Clinical Global Impression of Change (CGIC). The participants were grouped as responders (CGIC 1–3) or non-responders (CGIC 4–7). The 24-week RCT was followed by open-label treatment and survival was recorded at 36 months. Results After 36-month follow-up, patients in the memantine group had a longer length of survival compared with patients in the placebo group (log rank x²=4.02, p=0.045). Within the active treatment group, survival analysis 36 months from baseline showed that the memantine responders, based on CGIC, had higher rates of survival compared with the non-responders (log rank x²=6.595, p=0.010). Similar results were not seen in the placebo group. Conclusions Early treatment with memantine and a positive clinical response to memantine predicted longer survival in patients with DLB and PDD. This suggests a possible disease-modifying effect and also has implications for health economic analysis. However, owing to the small study sample, our results should merely be considered as generating a hypothesis which needs to be evaluated in larger studies. Trial registration number ISRCTN89624516.
A User's Guide to Solving Dynamic Stochastic Games Using the Homotopy Method

This paper provides a step-by-step guide to solving dynamic stochastic games using the homotopy method. The homotopy method facilitates exploring the equilibrium correspondence in a systematic fashion; it is especially useful in games that have multiple equilibria. We discuss the theory of the homotopy method and its implementation and present two detailed examples of dynamic stochastic games that are solved using this method.
A Coagulase- and α-Glucosidase-Negative Variant of Staphylococcus aureus: a Challenge for Routine Microbiological Diagnostics

Staphylococcus aureus can cause serious infections, toxinoses, and life-threatening illnesses. Staphylocoagulase production represents the major criterion for the detection of S. aureus isolates. As coagulase-deficient clinical isolates of S. aureus have been described, additional use of chromogenic
Examining the Relationship BetWeen Stress and Lack of Social Support in Mothers of Children With Autism

A selective, critical literature revieW is presented on the relationship betWeen stress and the paucity of social supports for mothers of children With autism. The published literature revieWed reveals an association betWeen challenging child characteristics and a mother's inclination to seek social support, With mothers under greater stress being more prone to pursue social support. For mothers of children With autism, informal support appeared to be a more effective stress-buffer than formal support. The cumulative results of several studies illustrated that parents Who received support related better emotionally to their children. Furthermore, loW levels of social support Were the most poWerful predictors of depression and anxiety in mothers.
Histological, histochemical and electron microscopic observations on synovial membrane

It is now generally accepted that the synovial fluid of joints is a transudate from the blood with added mucin (Allison, Fremont-Smith, Dailey and Kennard, '26 : Cajori, Crouter and Pemberton, '26). This much consists of a hyaluronic acid protein complex which is a highly hydrated flexible chain polymer (Ogston and Stanier, '53)' and contains no appreciable quantities of chondroitin sulphuric acid, the sulphated mucopolysaccharide of cartilage matrix. The various theories on the mode of production of synovial mucin are well reviewed by Bauer, Ropes and Waine ( '40), and Davies ( '43; '46). Vaubel ('33) has demonstrated mucin production by synovial cells in tissue culture and the current consensus of opinion is that it is likewise formed by some part of the synovial membrane i+z vivo. The synovial lining of joints varies considerably in appearance and cellularity according to local mechanical factors and the nature of the underlying tissue. According to Key ('28) the synovial surface a t pressure sites is flat and relatively acellular while elsewhere it is more cellular and irregularly disposed. Vaubel ( '33) has claimed a resemblance of synovial cells to osteoblasts and chondroblasts, a conception supported by King ('35) and others who believe synovial membrane to be a specialized tissue having mucin as its ground substance. 525
Preparation and Characterization of Trimethyl Chitosan Nanospheres Encapsulated with Tetanus Toxoid for Nasal Immunization Studies

Background: Mucosal immunization requires potent delivery systems and/or adjuvants to result in protective immunity. Polymeric nanospheres could be used as a delivery system and adjuvant for antigens. These nanospheres could improve the interaction of antigens and antigen presenting cells (APCs) and increase their immune stimulation potentials. Here we report on the preparation of trimethylated chitosan (TMC) nanospheres loaded with tetanus toxoid (TT). At the present study TMC was synthesized and its nanospheres encapsulated with TT were prepared and characterized for nasal immunization. Methods: At the present study TMC was synthesized by a two-step method. TMC nanospheres encapsulated with TT were prepared by ionic gelation method. Nanospheres were studied by Dynamic Light Scattering (DLS) and SEM for size and morphology.andThe zeta potential were determined by Zetasizer. Loading of TT was studied by BCA protein assay, release profile was studied for 4 h in 37 o C. Stability of loaded TT was evaluated by SDS-PAGE method. Results: Percent of quaternization for TMC was found to be 50.4  10.4%. Mean diameter of blank and loaded nanospheres was 243.2  35.1 nm and 295  48.5 nm, respectively. Encapsulation efficiency of TT in nanospheres was 60.3  12.7%. Percent of released TT after 0.5 h was 37.02  27.63% and after 4 h reached to 86.19  13.5%. Stability of encapsulated TT was confirmed by SDS-PAGE. Conclusion: The synthesized TMC polymer and its nanospheres loaded with TT showed desired characteristics as a mucosal antigen delivery system.
Computer simulation of copolymer phase behavior

Discontinuous molecular dynamics simulation is used to study the phase behavior of diblock copolymers modeled as chains of tangent hard spheres with square shoulder repulsions between unlike species as a function of chain length, volume fraction and interaction strength (χ). The location of the order–disorder transition for a symmetric copolymer is close to the predictions of Fredrickson and Helfand. Our simulation results for packing fractions of 0.35, 0.40, and 0.45 and chain lengths 10 and 20 are summarized in phase diagrams which display disordered, lamellae, perforated lamellae (PL), cylindrical, and BCC spherical (S) phases in the χN versus f plane. These phase diagrams are consistent with phase diagrams from other simulation studies. Contrary to theoretical predictions we observe the PL phase near regions of predicted gyroid stability, and the S phase only in the systems with high packing fraction and long chain length. These discrepancies may be due to the short chain lengths considered, as they a.
New method to design multiplier-less pulse shaping filters with minimal number of operations

Software-Defined Radio (SDR) technology is evolving rapidly, offering higher flexibility for wireless communication networks. For the sake of performance, and power consumption, filtering is commonly implemented in hardware using FPGAs. Pulse shaping in the transmitter and the corresponding matched filtering in the receiver, which together satisfy the Nyquist inter symbol interference (ISI) criterion, are no exception to this. To decrease the FPGA resources used by filters, to increase speed and to decrease power consumption the filter coefficients can be optimized by expressing them in canonical signed digit (CSD) form, using as few arithmetic operations per filter as possible, while maintaining acceptable filter characteristics. In this paper a new method to decrease the number of nonzero signed digits is presented. With this method a reduction of up to 65% of the nonzero signed digits per filter is realized, while decreasing the ISI ratio too.
Regulation of the O-Linked β-N-Acetylglucosamine Transferase by Insulin Signaling*

O-Linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of O-linked β-N-acetylglucosamine (O-GlcNAc) onto serine and threonine residues in response to stimuli or stress analogous to phosphorylation by Ser/Thr-kinases. Like protein phosphatases, OGT appears to be targeted to myriad specific substrates by transiently interacting with specific targeting subunits. Here, we show that OGT is activated by insulin signaling. Insulin treatment of 3T3-L1 adipocytes stimulates both tyrosine phosphorylation and catalytic activity of OGT. A subset of OGT co-immunoprecipitates with the insulin receptor. Insulin stimulates purified insulin receptor to phosphorylate OGT in vitro. OGT is a competitive substrate with reduced and carboxyamidomethylated lysozyme (RCAM-lysozyme), a well characterized insulin receptor substrate. Insulin stimulation of 3T3-L1 adipocytes results in a partial translocation of OGT from the nucleus to the cytoplasm. The insulin activation of OGT results in increased O-GlcNAc modification of OGT and other proteins including, signal transducer and activator of transcription 3 (STAT3). We conclude that insulin stimulates the tyrosine phosphorylation and activity of OGT.
Environmental robustness in automatic speech recognition

Initial efforts to make Sphinx, a continuous-speech speaker-independent recognition system, robust to changes in the environment are reported. To deal with differences in noise level and spectral tilt between close-talking and desk-top microphones, two novel methods based on additive corrections in the cepstral domain are proposed. In the first algorithm, the additive correction depends on the instantaneous SNR of the signal. In the second technique, expectation-maximization techniques are used to best match the cepstral vectors of the input utterances to the ensemble of codebook entries representing a standard acoustical ambience. Use of the algorithms dramatically improves recognition accuracy when the system is tested on a microphone other than the one on which it was trained. <<ETX>>
Aliasing-free simplification of surface meshes

We propose in this paper a robust simplification technique, which preserves geometric features such as sharp edges or corners from original surfaces. To achieve this goal, our simplification process relies on a detection tool that enables to preserve the sharp features during the three subsequent steps: a Poisson disk sampling that intelligently reduces the number of vertices of the initial mesh; the meshing of the samples that aligns the edges along the feature lines; and a constrained relaxation step that improves the shape of the triangles of our final simplified mesh. Experimental results show that our method always produces valid meshes without aliasing artifacts, and without giving up the shape fidelity and quality of the mesh elements.
IT Business Alignment as Governance Tool for Firm-Internal Relationship Quality: A Longitudinal Case Study

Many business processes are relying on a smooth and flexible IT support. A major finding of IS research is that in order to generate value from IT the complementarities between IT and non-IT resources need to be understood and orchestrated. Especially, IT business alignment has been found to be a key driver of both, IT value and business process quality. But how to achieve alignment? We present the results of a longitudinal case study in a globally active firm from the aerospace industry that shows how a new CEO implemented better business processes by increasing alignment. The results show an enhancing relationship between business and IT resources and concretize key findings from the resource based view. Overall, the case contributes by indicating that business value accrues from a simultaneous change of IS and business practices that was enabled by an increase in the level of IT business alignment.
Highly strained graphene samples of varying thickness and comparison of their behaviour

Mechanically straining graphene opens the possibility to exploit new properties linked to the stressed lattice of this two-dimensional material. In particular, theoretical analyses have forecast that straining graphene by more than 10% is a requirement for many novel applications that have not yet been experimentally demonstrated. Recently, we reported having achieved 12.5% strain in a trilayer graphene sample (3LG) in a controlled, reversible and non-destructive way. In this paper, we explore our method by straining samples of varying thicknesses and comparing their behavior, where strains of 14% and 11% were achieved for monolayer and four-layer graphene (4LG), respectively. For the analysis, optical tracking and the correspondent Raman spectra were taken. While doing so, we observed slippage between two layers in a bilayer sample of which one layer was clamped on one side only. The obtained results when stretching different samples to extreme strains demonstrated the exceptional elasticity of graphene, which might be essential for practical applications. Hysteretic effects observed in the partially clamped layer hints at small energy losses during slippage. This may shed new light on the superlubricity property of graphene that has been reported in the literature.
A MANAGEMENT OF THE THIRD STAGE TO REDUCE FETO‐MATERNAL TRANSFUSION

The size of feto‐maternal transfusion which occurs when fetal blood is allowed to run away from the divided umbilical cord as soon as the baby is delivered, is compared with that following the more orthodox management of the third stage. By using this method the average volume of transplacental transfusion and the incidence of detectable bleeds are reduced.
A comparison of the 3D kinematic measurements obtained by single-plane 2D-3D image registration and RSA

3D computed tomography (CT) to single-plane 2D fluoroscopy registration is an emerging technology for many clinical applications such as kinematic analysis of human joints and image-guided surgery. However, previous registration approaches have suffered from the inaccuracy of determining precise motion parameters for out-of-plane movements. In this paper we compare kinematic measurements obtained by a new 2D-3D registration algorithm with measurements provided by the gold standard Roentgen Stereo Analysis (RSA). In particular, we are interested in the out-of-plane translation and rotations which are difficult to measure precisely using a single plane approach. Our experimental results show that the standard deviation of the error for out-of-plane translation is 0.42 mm which compares favourably to RSA. It is also evident that our approach produces very similar flexion/extension, abduction/adduction and external knee rotation angles when compared to RSA.
Development of Highly Sensitive and Specific mRNA Multiplex System (XCYR1) for Forensic Human Body Fluids and Tissues Identification

The identification of human body fluids or tissues through mRNA-based profiling is very useful for forensic investigations. Previous studies have shown mRNA biomarkers are effective to identify the origin of biological samples. In this study, we selected 16 tissue specific biomarkers to evaluate their specificities and sensitivities for human body fluids and tissues identification, including porphobilinogen deaminase (PBGD), hemoglobin beta (HBB) and Glycophorin A (GLY) for circulatory blood, protamine 2 (PRM2) and transglutaminase 4 (TGM4) for semen, mucin 4 (MUC4) and human beta defensin 1(HBD1) for vaginal secretion, matrix metalloproteinases 7 and 11 (MMP7 and MMP11) for menstrual blood, keratin 4(KRT4) for oral mucosa, loricrin (LOR) and cystatin 6 (CST6) for skin, histatin 3(HTN3) for saliva, statherin (STATH) for nasal secretion, dermcidin (DCD) for sweat and uromodulin (UMOD) for urine. The above mentioned ten common forensic body fluids or tissues were used in the evaluation. Based on the evaluation, a reverse transcription (RT) PCR multiplex assay, XCYR1, which includes 12 biomarkers (i.e., HBB, GLY, HTN3, PRM2, KRT4, MMP11, MUC4, DCD, UMOD, MMP7, TGM4, and STATH) and 2 housekeeping genes [i.e., glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and 18SrRNA], was developed. This assay was further validated with real casework samples and mock samples (with both single source and mixture) and it was approved that XCYR1 is effective to identify common body fluids or tissues (i.e., circulatory blood, saliva, semen, vaginal secretion, menstrual blood, oral mucosa, nasal secretion, sweat and urine) in forensic casework samples.
Velocity Structure of Jets in a Coronal Hole

The velocity structures of jets in a coronal hole have been derived for the first time. Hinode observations revealed the existence of many bright points in coronal holes. They are loop-shaped and sometimes associated with coronal jets. Spectra obtained with the Extreme-ultraviolet Imaging Spectrometer aboard Hinode were analyzed to infer the Doppler velocity of bright loops and jets in a coronal hole of the north polar region. Elongated jets above bright loops are found to be blue-shifted by 30 km s 1 at maximum, while foot points of bright loops are red-shifted. Blue-shifts detected in coronal jets are interpreted as being upflows produced by magnetic reconnection between emerging flux and the ambient field in the coronal hole.