Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk Factors of Eclampsia Other Than Hypertension: Pregnancy-Induced Antithrombin Deficiency and Extraordinary Weight Gain

Objective. Recent findings suggest that cerebral edema is a characteristic finding on magnetic resonance imaging in women with eclampsia and that pregnancy-induced antithrombin deficiency (PIATD) may reflect enhanced vascular permeability and may allow the retention of excess water in the interstitial space. Whether PIATD and extraordinary weight gain (EOWG) are risk factors for eclampsia remains to be studied. Methods. The medical records of 11 women with eclampsia among 17,522 deliveries were reviewed retrospectively with respect to changes in the laboratory data and the maternal body weight. PIATD was defined as a perinatal antithrombin activity of ≤65% of the normal activity levels with an antenatal decline and/or a prompt postnatal increase. A large net weight gain during the last two antenatal weeks >97.5th percentile value (>4.01 kg) obtained from 272 control women with neither hypertension nor PIATD was defined as EOWG. Relative risk was obtained on the assumption that the prevalences of PIATD and EOWG were 2.0 and 2.5%, respectively, among 17,511 women who did not develop eclampsia. Results. The duration of hypertension until an eclamptic fit was within 7 days in all 11 cases. PIATD and EOWG were observed in 6 (54.5%) and 2 (18.2%) cases, yielding a relative risk (95% confidential interval) of 57.9 (17.7–188.7) and 8.65 (1.87–39.91) for eclampsia among women with PIATD and EOWG, respectively. Conclusions. PIATD and EOWG may be risk factors for eclampsia.
Development of Religious Identity Through Doubts Among Religious Adolescents in Israel: An Empirical Perspective and Educational Ramifications

Abstract Researchers have been demonstrating interest in doubts regarding religious faith for thirty years. The current study goal was examining differences between three groups of religious male adolescents in Israel, regarding faith identity, doubts in religious faith (past and present), religious behavior, and the connection between them. Three questionnaires were answered by 472 religious Israeli male 9th, 10th, and 11th graders, regarding faith identity, religious behavior, and faith doubts. A MANOVA indicated significant differences between the groups for all research variables. Separate regression analyses for each age group for predicting faith identity according to doubts, produced very different pictures. Tenth grade seems the most important crossroads in forming religious identity.
Complementary DNA sequencing: expressed sequence tags and human genome project

Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs). ESTs have applications in the discovery of new human genes, mapping of the human genome, and identification of coding regions in genomic sequences. Of the sequences generated, 337 represent new genes, including 48 with significant similarity to genes from other organisms, such as a yeast RNA polymerase II subunit; Drosophila kinesin, Notch, and Enhancer of split; and a murine tyrosine kinase receptor. Forty-six ESTs were mapped to chromosomes after amplification by the polymerase chain reaction. This fast approach to cDNA characterization will facilitate the tagging of most human genes in a few years at a fraction of the cost of complete genomic sequencing, provide new genetic markers, and serve as a resource in diverse biological research fields.
WHAT DO WE KNOW ABOUT BILINGUAL EDUCTION FOR MAJORITY LANGUAGE STUDENTS?

In many communities around the world, competence in two, or more, languages is an issue of considerable personal, socio-cultural, economic, and political significance. For some, the issues surrounding bilingualism are viewed as “problems” to be overcome; for others, they are viewed as “challenges” that, once mastered, benefit the individual, the community, and even the nation in which they live. The need to know two or more languages is not new. Historical documents indicate that individuals and whole communities around the world have been compelled to learn other languages for centuries and they have done so for a variety of reasons -language contact, colonization, trade, education through a colonial language (e.g., Latin, Greek), and intermarriage (Lewis, 1977). Notwithstanding historical patterns, changes in the modern world are presenting new incentives for learning additional languages. • There is growing globalization of business and commerce. During the last 10-15 years we have witnessed unprecedented internationalization of industry and white collar businesses -for example, in the automotive industry, head offices are located in one country (e.g., Japan), manufacture of automobiles takes place in another country (e.g., Brazil), and clients are in a third country (e.g., Canada). Even in North America, a relatively homogeneous linguistic community and trade zone, we are challenged to learn other languages to remain competitive -for example, in response to the Spanish-speaking markets in Mexico and the Frenchspeaking market in Quebec. While globalization of the market place often provokes images of English domination, it also increases the demand to do business in local or regional languages (Walraff, 2000). • A revolution in electronic communications has also created a need for proficiency in multiple languages. The Internet makes global communication available and easy, whether it be for
How do personality factors influence attitudes towards counterfeiting of luxury brands

This paper examines how personality factors influence attitudes towards counterfeiting of luxury brands and purchase intention. Attitudes towards counterfeiting of luxury brands is found to influence purchase intention. A factor analysis of the scale “attitudes towards counterfeiting of luxury brands” revealed two factors, which are namely “perceptions of counterfeits” and “social consequences”. Status consumption and integrity are strong influencers of purchase intention, whereas personal gratification, value consciousness, and novelty seeking had weaker influencing relationships. The research findings can be used to formulate strategies to better counter counterfeiting.
harmacologyOnLine Migraine and Epistaxis : Clinical and Therapeutic Evidences

Migraine is a common neurological disorder characterized by painful episodes sometimes preceded by transient neurological symptoms and reversible defined migraine aura. Rarer forms of migraine are hemiplegic migraine, familial and sporadic, the retinal migraine and migraine equivalents. For the two most common forms of migraine with and without aura, the prevalence appears to be higher in females (5% and 11% respectively). In the literature there are very rare reports of primary migraine associated with epistaxis. Therefore, in the present study we have observed a series of patients with migraine-associated phenomena recurrent epistaxis in order to define the clinical features and therapeutic response to flunarizine. The study sample consists of 12 patients (7F and 5 M) suffering from migraine without aura (ICHD-II04 criteria) accompanied by epistaxis, migraine with a history of at least one year and an average age of 23.2 years (range 20-38). In 10 patients, episodes of migraine most often presented themselves during the day with epistaxis small claims, in a case of such gravity as to refer for medical treatment under emergency. In the other 2 patients, the headache, the higher frequency compared to the previous cases, it appeared only during sleep and is constantly accompanied episodes of moderate epistaxis. All patients were subjected to neurological examination, ENT and cardiology, holter pressure, routine laboratory tests and PT, PTT, fibrinogen, AT-III, d-dimer, EEG, CT and / or MRI brain, CT High focused on the definition of the facial complex ostiomeatale. All examinations were normal. Patients were subjected to drug therapy at a dose of flunarizine with 5mg/die, for three months, with significant (P <0.05) reduction in the frequency of attacks monitored through a paper diary to monthly follow-ups and disappearance of the episodes of epistaxis. In literature there are rare case reports of forms of primary headache associated with epistaxis. In our series of patients there is a definite diagnosis of migraine without aura with epistaxis closely associated with headache without any risk factor for epistaxis. The pathogenesis of epistaxis in migraine may be related to the complex vascular disorder at the base of this frequent neurological disorder. Based on this consideration, we subjected the patients to prophylactic therapy with a calcium channel blocker, the flunarizine, which resulted in not only a significant reduction in episodes of headache, but also the disappearance of epistaxis. Thus we seem to be able to conclude that migraine with epistaxis is an uncommon variant of migraine, the frequency is higher in females and can present an optimal response to drugs that modulate the tone of the vessel wall, such as calcium channel blockers.
Fish Oil Reduces Heart Rate and Oxygen Consumption During Exercise

Dietary omega-3 polyunsaturated fatty acids (PUFAs) are readily incorporated into heart and skeletal muscle membranes where, in the heart, animal studies show they reduce O2 consumption. To test the hypothesis that omega-3 PUFAs alter O2 efficiency in humans, the effects of fish oil (FO) supplementation on O2 consumption during exercise were evaluated. Sixteen well-trained men (cyclists), randomly assigned to receive 8 × 1 g capsules per day of olive oil (control) or FO for 8 weeks in a double-blind, parallel design, completed the study (control: n = 7, age 27.1 ± 2.7 years; FO: n = 9, age 23.2 ± 1.2 years). Subjects used an electronically braked cycle ergometer to complete peak O2 consumption tests (VO2peak) and sustained submaximal exercise tests at 55% of peak workload (from the VO2peak test) before and after supplementation. Whole-body O2 consumption and indirect measurements of myocardial O2 consumption [heart rate and rate pressure product (RPP)] were assessed. FO supplementation increased omega-3 PUFA content of erythrocyte cell membranes. There were no differences in VO2peak (mL kg−1 min−1) (control: pre 66.8 ± 2.4, post 67.2 ± 2.3; FO: pre 68.3 ± 1.4, post 67.2 ± 1.2) or peak workload after supplementation. The FO supplementation lowered heart rate (including peak heart rate) during incremental workloads to exhaustion (P < 0.05). In addition, the FO supplementation lowered steady-state submaximal exercise heart rate, whole-body O2 consumption, and RPP (P < 0.01). Time to voluntary fatigue was not altered by FO supplementation. This study indicates that FOs may act within the healthy heart and skeletal muscle to reduce both whole-body and myocardial O2 demand during exercise, without a decrement in performance.
Preferential Decarboxylation of Hydrophilic Phosphatidylserine Species in Cultured Cells

In baby hamster kidney and other cultured cells the majority of phosphatidylethanolamine (PE) is synthesized from phosphatidylserine (PS) in a process which involves transport of PS from the endoplasmic reticulum to mitochondria and decarboxylation therein by PS decarboxylase. To study the mechanism of this transport process, we first determined the molecular species composition of PE and PS from baby hamster kidney and Chinese hamster ovary cells. Interestingly, the hydrophilic diacyl molecular species were found to be much more abundant in PE than in PS, suggesting that hydrophilic PS species may be more readily transported to mitochondria than the hydrophobic ones. To study this, we compared the rates of decarboxylation of different PS molecular species in these cells. The cells were pulse labeled with [3H]serine whereafter the distribution of the labels among PS and PE molecular species was determined by reverse phase high performance liquid chromatography and liquid scintillation counting. The hydrophilic PE species contained relatively much more 3H label than those of PS, which indicates that they are more readily decarboxylated than the hydrophobic ones. Control experiments showed that differences in [3H]PS and -PE molecular species profiles are not due to (i) incorporation of 3H label to some PE species via alternative pathways, (ii) differences in degradation or remodeling among species, or (iii) selective decarboxylation of PS molecular species by the enzyme. Therefore, hydrophilic PS species are indeed decarboxylated faster than the hydrophobic ones. The rate of decarboxylation decreased systematically with hydrophobicity, strongly suggesting that formation of so called activated monomers,i.e. lipid molecules perpendicularly displaced from the membrane (Jones, J. D., and Thompson, T. E. (1990)Biochemistry 29, 1593–1600), is the rate-limiting step in the transport of PS from the endoplasmic reticulum to mitochondria. The formation of activated monomers and thus the rate of transfer is probably greatly enhanced by frequent collisions between the two membranes which tend to be closely associated. The present data also provides a feasible explanation why hydrophilic molecular species in these cells are much more abundant in PE as compared with PS, its immediate precursor.
Subspace Based Network Community Detection Using Sparse Linear Coding

Information mining from networks by identifying communities is an important problem across a number of research fields including social science, biology, physics, and medicine. Most existing community detection algorithms are graph theoretic and lack the ability to detect accurate community boundaries if the ratio of intra-community to inter-community links is low. Also, algorithms based on modularity maximization may fail to resolve communities smaller than a specific size if the community size varies significantly. In this paper, we present a fundamentally different community detection algorithm based on the fact that each network community spans a different subspace in the geodesic space. Therefore, each node can only be efficiently represented as a linear combination of nodes spanning the same subspace. To make the process of community detection more robust, we use sparse linear coding with l1 norm constraint. In order to find a community label for each node, sparse spectral clustering algorithm is used. The proposed community detection technique is compared with more than 10 state of the art methods on two benchmark networks (with known clusters) using normalized mutual information criterion. Our proposed algorithm outperformed existing algorithms with a significant margin on both benchmark networks. The proposed algorithm has also shown excellent performance on three real-world networks.
Hepatitis Delta Virus: Epidemiology, Natural Course and Treatment

The hepatitis delta virus (HDV) is a defective hepatotropic virus that affects only patients with hepatitis B virus (HBV) infection. These 2 viruses share the same routes of transmission (parenteral, sexual, and mother to child). The hepatitis delta virus infection may result in acute hepatitis, including fulminant presentation or spontaneously resolving infection, and chronic infection. The prognosis depends on the chronology of the 2 infections, co-infection (higher risk of fulminant hepatitis) or super-infection (frequent evolution to chronicity). The harmfull impact of HIVassociated infection is today debated even if HDV antibodies are present in 12% and 4% of HIV/HBV co-infected and HBV-mono-infected patients respectively. HDV may be treated by interferon, the unique treatment, but relapse is observed in 50% of cases after discontinuation of therapy: only 25% of treated patients achieved a sustained virologic response. Entry HBV/HDV inhibitors (Myrcludex) and prenylation inhibitors are awaited encouraging progress in treating HDV infection. The treatment is recommended in patients with significant fibrosis; viral suppression may result in fibrosis stabilization or reversal which may be also observed in the absence of complete viral eradication. The prevention of hepatitis delta virus infection is based on hepatitis B virus vaccination
Folic Acid Supplementation Stimulates Notch Signaling and Cell Proliferation in Embryonic Neural Stem Cells

The present study investigated the effect of folic acid supplementation on the Notch signaling pathway and cell proliferation in rat embryonic neural stem cells (NSCs). The NSCs were isolated from E14–16 rat brain and grown as neurospheres in serum-free suspension culture. Individual cultures were assigned to one of 3 treatment groups that differed according to the concentration of folic acid in the medium: Control (baseline folic acid concentration of 4 mg/l), low folic acid supplementation (4 mg/l above baseline, Folate-L) and high folic acid supplementation (40 mg/l above baseline, Folate-H). NSCs were identified by their expression of immunoreactive nestin and proliferating cells by incorporation of 5'bromo-2'deoxyuridine. Cell proliferation was also assessed by methyl thiazolyl tetrazolium assay. Notch signaling was analyzed by real-time PCR and western blot analyses of the expression of Notch1 and hairy and enhancer of split 5 (Hes5). Supplementation of NSCs with folic acid increased the mRNA and protein expression levels of Notch1 and Hes5. Folic acid supplementation also stimulated NSC proliferation dose-dependently. Embryonic NSCs respond to folic acid supplementation with increased Notch signaling and cell proliferation. This mechanism may mediate the effects of folic acid supplementation on neurogenesis in the embryonic nervous system.
Adsorption, Kinetic, Equilibrium and Thermodynamic studies on the removal of basic dye Rhodamine-B from aqueous solution by the use of natural adsorbent perlite

This paper presents the feasibility of removal of b asic dye Rhodamine-B from aqueous solutions by using a low cost natural adsorbent perlite. Batch adsorptio n experiments were carried out as a function of pH, contact time, initial concentration of the adsorbat e, adsorbent dosage and temperature. Dye adsorption equilibrium was rapidly attained after 50 minutes o f the contact time, and it was described by the Lan gmuir and Freundlich adsorption isotherms over the entire concentration ranges from 20-100 mgL -1 . Adsorption data’s are used for modelling, from the first and s econd order kinetic equation and intra-particle dif fusion models. Thermodynamic parameters such as ∆H o , ∆S o , and ∆G o were calculated, which indicated that the adsorption was spontaneous and exothermic nature, which was evident by decreasing the randomness of the dye at the solid and liquid interface. Adsorbent us ed in this study, characterized by FT-IR and SEM be fore and after the adsorption of Rhodamine-B. The characteristic results and dimensionless separation facto rs (R L) showed that perlite can be employed as an alterna tive to commercial adsorbents in the removal of Rhodamine-B from aqueous solution and waste water.
Lactase dehydrogenase as a tumor marker for recurrent disease in Ewing's sarcoma

The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow‐up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was found to have no prognostic value. Both patients with elevated and normal LDH levels had the same survival rate. The LDH level at recurrence was significantly higher, however, than the follow‐up LDH level of those without recurrence (P < 0.001). The LDH level was most sensitive as a tumor marker for recurrent disease in those patients with multiple sites of tumor involvement at the time of recurrence.
The relationship between gender and classroom environment in Turkish science classrooms

The purpose of this study was to explore the relationship of gender between actual and preferred classroom environment and use of technology in the science classroom of Turkish students. Employing stratified random sampling procedures, data were collected from 985 students from schools across twelve different districts in Istanbul, Turkey. The Technology-Rich Outcomes-Focused Learning Environment Inventory (TROFLEI), developed by Aldridge and Fraser (2003), was used in this study. The TROFLEI was translated into Turkish using a multistep process. Independent samples t-tests were conducted on each of the scale items to evaluate the relationship between gender and the students’ actual and preferred use of technology in the science classroom. Our findings show that differences clearly exist between genders in their actual and preferred perceptions of classroom environment and their use of technology in the science classroom. This knowledge can serve as valuable information as educational reforms continue to evolve and educators seek to reach all students in their classrooms. Key words: Science classroom, gender, Technology-Rich Outcomes-Focused Learning Environment, TROFLEI, classroom environment, cross-cultural validation.
The Teaching Principal: An Untenable Position or a Promising Model?

This paper reports on an interpretive study that examined the role of the teaching principal, particularly as it relates to principals’ moral and legal requirement to work as instructional leaders for student learning. A teaching principal is defined as a principal who has a “double load” or dual roles in teaching and administration (Clarke & Stevens, 2009). In this study, we explored the constitution and effects of this role on individuals and leadership practices of 12 rural teaching principals in Alberta and Manitoba. Findings reflect the need to develop policies that sustain the smaller schools which depend upon administrators capable of thriving in this dual role. Additionally, the way in which teaching principals practice as instructional leaders promises to enrich the literature on instructional leadership. Specifically, the practices that emerge through the teaching principalship are a unique adaptation of existing conceptualizations that offer considerable advantages over those that presuppose a full-time administrative appointment. Cet article rend compte d’une étude interprétative portant sur le rôle du directeur enseignant, notamment par rapport à l’exigence morale et juridique qu’ont les directeurs de travailler comme leaders pédagogiques. Un directeur enseignant en est un qui a une « double charge », qui joue deux rôles, un en enseignement et un en administration (Clarke & Stevens, 2009). Dans cette étude, nous avons exploré la création et les effets de ce rôle sur les individus et sur les pratiques de leadership de douze directeurs enseignants en milieu rural en Alberta et au Manitoba. Les résultats reflètent la nécessité de développer des politiques qui appuient les plus petites écoles qui dépendent d’administrateurs en mesure de prospérer dans le contexte de ce double rôle. De plus, les pratiques qu’emploient les directeurs enseignants dans leur capacité de leaders pédagogiques promettent d’enrichir la littérature sur le leadership pédagogique. Plus spécifiquement, les pratiques qui ressortent des pratiques des directeurs enseignants constituent une adaptation unique des conceptualisations existantes, une qui offre un nombre considérable d’avantages par rapport à celles qui présupposent un poste administratif à temps plein.