Miracle-dz/UniFAR-FTUs huggingface dataset:
Word embeddings quantify 100 years of gender and ethnic stereotypes

Significance Word embeddings are a popular machine-learning method that represents each English word by a vector, such that the geometry between these vectors captures semantic relations between the corresponding words. We demonstrate that word embeddings can be used as a powerful tool to quantify historical trends and social change. As specific applications, we develop metrics based on word embeddings to characterize how gender stereotypes and attitudes toward ethnic minorities in the United States evolved during the 20th and 21st centuries starting from 1910. Our framework opens up a fruitful intersection between machine learning and quantitative social science. Word embeddings are a powerful machine-learning framework that represents each English word by a vector. The geometric relationship between these vectors captures meaningful semantic relationships between the corresponding words. In this paper, we develop a framework to demonstrate how the temporal dynamics of the embedding helps to quantify changes in stereotypes and attitudes toward women and ethnic minorities in the 20th and 21st centuries in the United States. We integrate word embeddings trained on 100 y of text data with the US Census to show that changes in the embedding track closely with demographic and occupation shifts over time. The embedding captures societal shifts—e.g., the women’s movement in the 1960s and Asian immigration into the United States—and also illuminates how specific adjectives and occupations became more closely associated with certain populations over time. Our framework for temporal analysis of word embedding opens up a fruitful intersection between machine learning and quantitative social science.
Phenotypic variation explains food web structural patterns

Significance Understanding food web structure—networks of species and their feeding interactions—is central to predicting how ecosystems may respond to climate change. Feeding interactions are often determined by the traits individuals have, but how the effects of such traits and their intraspecific variation scale up from individuals to food webs is not known. Here, we use mathematical models to show that trait variation influences predator connectivity and trophic level within food webs. By doing so, we predict the occurrence of important structural features in food webs, and we confirm these predictions using a large global dataset of the best-resolved available food webs. Food webs (i.e., networks of species and their feeding interactions) share multiple structural features across ecosystems. The factors explaining such similarities are still debated, and the role played by most organismal traits and their intraspecific variation is unknown. Here, we assess how variation in traits controlling predator–prey interactions (e.g., body size) affects food web structure. We show that larger phenotypic variation increases connectivity among predators and their prey as well as total food intake rate. For predators able to eat only a few species (i.e., specialists), low phenotypic variation maximizes intake rates, while the opposite is true for consumers with broader diets (i.e., generalists). We also show that variation sets predator trophic level by determining interaction strengths with prey at different trophic levels. Merging these results, we make two general predictions about the structure of food webs: (i) trophic level should increase with predator connectivity, and (ii) interaction strengths should decrease with prey trophic level. We confirm these predictions empirically using a global dataset of well-resolved food webs. Our results provide understanding of the processes structuring food webs that include functional traits and their naturally occurring variation.
Genetic Polymorphisms of the Mitochondrial Aldehyde Dehydrogenase ALDH2 Gene in a Large Ethnic Hakka Population in Southern China

Background Human mitochondrial aldehyde dehydrogenase 2 (ALDH2) plays a critical role in the detoxification of the ethanol metabolite acetaldehyde. The ALDH2*2 (rs671) gene variant is mainly absent among Europeans but is prevalent in populations in East Asia. The aim of this study was to investigate ALDH2*2 mutant alleles and genotype frequencies in the Hakka population of China. Material/Methods Between January 2016 and June 2017, 7,966 unrelated individuals were recruited into the study from the Hakka ethnic population residing in the Meizhou area of Guangdong Province, China, who provided venous blood samples. Genotyping of ALDH2 genotypes were determined using a gene chip platform and confirmed by DNA sequencing. Results In the 7,966 individuals from the Hakka population of China in this study, the frequencies of the ALDH2 genotypes *1/*1, *1/*2 and *2/*2 were 52.03%, 39.67%, and 8.30%, respectively; 47.97% of the individuals were found to carry the ALDH2*2 genotype, which was associated with a deficiency in the aldehyde dehydrogenase (ALDH2) enzyme activity. The frequency of the ALDH2*2 allele was lower than that previously reported in the Japanese population but higher than that reported in other Oriental populations. Conclusions The findings of this study have provided new information on the ALDH2 gene polymorphisms in the Hakka ethnic population residing in the Meizhou area of Guangdong Province, China, including an understanding of the origin of the atypical ALDH2*2 allele. Also, the study findings may be relevant to the primary care of patients in China.
Pressure-anisotropy-induced nonlinearities in the kinetic magnetorotational instability

In collisionless and weakly collisional plasmas, such as hot accretion flows onto compact objects, the magnetorotational instability (MRI) can differ significantly from the standard (collisional) MRI. In particular, pressure anisotropy with respect to the local magnetic-field direction can both change the linear MRI dispersion relation and cause nonlinear modifications to the mode structure and growth rate, even when the field and flow perturbations are very small. This work studies these pressure-anisotropy-induced nonlinearities in the weakly nonlinear, high-ion-beta regime, before the MRI saturates into strong turbulence. Our goal is to better understand how the saturation of the MRI in a low-collisionality plasma might differ from that in the collisional regime. We focus on two key effects: (i) the direct impact of self-induced pressure-anisotropy nonlinearities on the evolution of an MRI mode, and (ii) the influence of pressure anisotropy on the ‘parasitic instabilities’ that are suspected to cause the mode to break up into turbulence. Our main conclusions are: (i) The mirror instability regulates the pressure anisotropy in such a way that the linear MRI in a collisionless plasma is an approximate nonlinear solution once the mode amplitude becomes larger than the background field (just as in magnetohyrodynamics). This implies that differences between the collisionless and collisional MRI become unimportant at large amplitudes. (ii) The break up of large-amplitude MRI modes into turbulence via parasitic instabilities is similar in collisionless and collisional plasmas. Together, these conclusions suggest that the route to magnetorotational turbulence in a collisionless plasma may well be similar to that in a collisional plasma, as suggested by recent kinetic simulations. As a supplement to these findings, we offer guidance for the design of future kinetic simulations of magnetorotational turbulence.
Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure

BACKGROUND Adolescent intermittent ethanol (AIE) exposure produces persistent impairments in cholinergic and epigenetic signaling and alters markers of synapses in the hippocampal formation, effects that are thought to drive hippocampal dysfunction in adult rodents. Donepezil (Aricept), a cholinesterase inhibitor, is used clinically to ameliorate memory-related cognitive deficits. Given that donepezil also prevents morphological impairment in preclinical models of neuropsychiatric disorders, we investigated the ability of donepezil to reverse morphological and epigenetic adaptations in the hippocampus of adult rats exposed to AIE. Because of the known relationship between dendritic spine density and morphology with the fragile X mental retardation 1 (Fmr1) gene, we also assessed Fmr1 expression and its epigenetic regulation in hippocampus after AIE and donepezil pretreatment. METHODS Adolescent rats were administered intermittent ethanol for 16 days starting on postnatal day 30. Rats were treated with donepezil (2.5 mg/kg) once a day for 4 days starting 20 days after the completion of AIE exposure. Brains were dissected out after the fourth donepezil dose, and spine analysis was completed in dentate gyrus granule neurons. A separate cohort of rats, treated identically, was used for molecular studies. RESULTS AIE exposure significantly reduced dendritic spine density and altered morphological characteristics of subclasses of dendritic spines. AIE exposure also increased mRNA levels and H3-K27 acetylation occupancy of the Fmr1 gene in hippocampus. Treatment of AIE-exposed adult rats with donepezil reversed both the dendritic spine adaptations and epigenetic modifications and expression of Fmr1. CONCLUSIONS These findings indicate that AIE produces long-lasting decreases in dendritic spine density and changes in Fmr1 gene expression in the hippocampal formation, suggesting morphological and epigenetic mechanisms underlying previously reported behavioral deficits after AIE. The reversal of these effects by subchronic, post-AIE donepezil treatment indicates that these AIE effects can be reversed by up-regulating cholinergic function.
Number density structures in the inner heliosphere

The origins and generation mechanisms of the slow solar wind are still unclear. Part of the slow solar wind is populated by "number density structures", discrete patches of increased number density that are frozen in to and move with the bulk solar wind. In this paper we aimed to provide the first in-situ statistical study of number density structures in the inner heliosphere. We reprocessed in-situ ion distribution functions measured by Helios in the inner heliosphere to provide a new reliable set of proton plasma moments for the entire mission. From this new data set we looked for number density structures measured within 0.5 AU of the Sun and studied their properties. We identified 140 discrete areas of enhanced number density. The structures occurred exclusively in the slow solar wind and spanned a wide range of length scales from 50 Mm to 2000 Mm, which includes smaller scales than have been previously observed. They were also consistently denser and hotter that the surrounding plasma, but had lower magnetic field strengths, and therefore remained in pressure balance. Our observations show that these structures are present in the slow solar wind at a wide range of scales, some of which are too small to be detected by remote sensing instruments. These structures are rare, accounting for only 1\% of the slow solar wind measured by Helios, and are not a significant contribution to the mass flux of the solar wind.
Barriers to Health Service Utilization Among Iranian Female Sex Workers: A Qualitative Study

Objectives In most countries around the world, sex work is an illegal activity. Female sex workers (FSWs) in Iran hide their identities, and they are known to be a hard-to-reach population. Despite free access to HIV testing, fewer than half of FSWs receive HIV testing. The purpose of this study was to characterize the reasons for which FSWs do not seek testing at drop-in centers (DICs) and voluntary counseling and testing (VCT) centers in Iran. Methods A qualitative study was conducted in 2016. The participants were 24 FSWs who received services at VCT centers and DICs for vulnerable females in the north of Iran and 9 males who were the clients of FSWs. In this study, we made use of purposive sampling and carried out a thematic analysis. Results We found 4 major and 6 minor themes. The major themes were: fear of being infected (with HIV), stigma, indifference, and knowledge. Conclusions Despite the significant efforts made by the government of Iran to establish and expand DICs for vulnerable females, the number of FSWs receiving services at these centers has not been very considerable. Consequently, by introducing and implementing training programs for peer groups, it may be possible to take steps toward establishing strategic programs for the control and prevention of HIV/AIDS.
The role of emotions in depression and aggression

Background Depression is a broad and heterogeneous diagnostic grouping, central to which is depressed mood or inability to enjoy most activities. Depressive symptoms are frequently accompanied by conduct problems stemming from anger. It is very important to know the interrelation of these emotions very well to be able to help adolescents to manage them more easily. The main aim of this article is to present the problem of interaction between negative affects (emotional instability, anger state and trait, physical and verbal aggression and depression) analyzing the different relationship through the time in spanish sample. Material and Methods The sample included 470 adolescents (192 boys and 225 girls) in a three-wave longitudinal study in Valencia (Spain). The mean age was 14.70 in the first wave. Structural equations modelling was employed to explore two longitudinal models. Results The results show differences based on sex, and that an internalised variable, like emotional instability, is relevant to prevent the appearance of depression directly in girls and also the later appearance of aggression as long as anger mediates, in both boys and girls, so the control of anger becomes an important goal to control the rest of the negative affects. Conclusions This results has consequences in the preparation of all programmes that try to establish an emotional control on adolescents, as not only has to be taken into account as a direct goal the control of externalised emotions like anger, but internalised emotions like emotional instability have to be taken into account also. Furthermore, it is also made apparent that not only the punctual explosions and externalisation of anger have to be worked on, but the temperamental aspects which are the base of anger trait have to be worked on too. Key words:Emotional instability, anger, depression, aggression, negative emotions, adolescence.
Development of multi-functional cotton surface for sportswear using nano zinc oxide

ABSTRACT This paper reports the development of multi-functional cotton knitted fabric by two-stage process. Cotton knitted fabric was finished with in situ generated nano zinc oxide (nano-ZnO) followed by electrospraying Arkophop FFR a non-fluorocarbon-based hydrophobic chemical. Electrospraying was carried out with different flow rates (0.01 and 0.02 mL/min) and durations (1– min) with the help of microprocessor controlled syringe pump. The fabric was analyzed for its antimicrobial, UV protective, and moisture management (MMT) properties. FTIR study confirmed the formation of hydrophobic chemical finish on one surface of cotton fabrics. Scanning electron microscope observation showed the presence of nano-ZnO and hydrophobic finish on the electrosprayed surface of the cotton fabric. One-way moisture transport rating of the treated fabric using MMT test was found to be very good for 0.01 mL/min flow rate of the hydrophobic chemical for duration of 3 min using an optimized voltage of 20 kV and the distance of 15 cm between the nozzle and the collector. In situ generated nano-ZnO positively influenced the MMT properties of the treated cotton fabric.
Molecular Characterization of Human Respiratory Syncytial Virus in the Philippines, 2012-2013

Human respiratory syncytial virus (HRSV) is a major cause of acute lower respiratory tract infections in infants and children worldwide. We performed molecular analysis of HRSV among infants and children with clinical diagnosis of severe pneumonia in four study sites in the Philippines, including Biliran, Leyte, Palawan, and Metro Manila from June 2012 to July 2013. Nasopharyngeal swabs were collected and screened for HRSV using real-time polymerase chain reaction (PCR). Positive samples were tested by conventional PCR and sequenced for the second hypervariable region (2nd HVR) of the G gene. Among a total of 1,505 samples, 423 samples were positive for HRSV (28.1%), of which 305 (72.1%) and 118 (27.9%) were identified as HRSV-A and HRSV-B, respectively. Two genotypes of HRSV-A, NA1 and ON1, were identified during the study period. The novel ON1 genotype with a 72-nucleotide duplication in 2nd HVR of the G gene increased rapidly and finally became the predominant genotype in 2013 with an evolutionary rate higher than the NA1 genotype. Moreover, in the ON1 genotype, we found positive selection at amino acid position 274 (p<0.05) and massive O- and N-glycosylation in the 2nd HVR of the G gene. Among HRSV-B, BA9 was the predominant genotype circulating in the Philippines. However, two sporadic cases of GB2 genotype were found, which might share a common ancestor with other Asian strains. These findings suggest that HRSV is an important cause of severe acute respiratory infection among children in the Philippines and revealed the emergence and subsequent predominance of the ON1 genotype and the sporadic detection of the GB2 genotype. Both genotypes were detected for the first time in the Philippines.
Association of Peripheral Artery Disease With Incident Atrial Fibrillation: The ARIC (Atherosclerosis Risk in Communities) Study

Background Although peripheral artery disease as defined by ankle‐brachial index (ABI) is associated with incident atrial fibrillation (AF), questions remain about the risk of AF in borderline ABI (>0.90 to <1.0) or noncompressible arteries (>1.4). We evaluated the association of borderline ABI and ABI >1.4 in the ARIC (Atherosclerosis Risk in Communities) study, a population‐based prospective cohort study. Methods and Results We included 14 794 participants (age, 54.2±5.8 years, 55% women, 26% blacks) with ABI measured at the baseline (1987–1989) and without AF. AF was identified from hospital records, death certificates, and ECGs. Using Cox proportional hazards, we evaluated the association between ABI and AF. During a median follow‐up of 23.3 years, there were 2288 AF cases. After adjustment for cardiovascular risk factors, hazard ratio (HR) (95% confidence interval) for AF among individuals with ABI <1.0 compared with ABI 1.0 to 1.4, was 1.13 (1.01–1.27). ABI >1.4 was not associated with increased AF risk. ABI ≤0.9 and borderline ABI were associated with a higher risk of AF compared with ABI 1.0 to 1.4. Demographics‐adjusted HRs (95% confidence interval) were 1.43 (1.17–1.75) and 1.32 (1.16–1.50), respectively. However, the associations of ABI ≤0.9 and borderline ABI with AF were attenuated after adjusting for cardiovascular risk factors (HR [95% confidence interval], 1.10 [0.90–1.34] and 1.14 [1.00–1.30]), respectively. Conclusions Peripheral artery disease indicated by low ABI, including borderline ABI, is a weak risk factor for AF. ABI >1.4 is not associated with an increased AF risk. The relationship between peripheral artery disease and AF appears to be mostly explained by traditional atherosclerotic risk factors.
A new species of Paraonis and an annotated checklist of polychaetes from mangroves of the Brazilian Amazon Coast (Annelida, Paraonidae)

Abstract The polychaete fauna from the mangroves of the Amazon Coast in Maranhão state, Brazil, is reported in this study. Fourteen species are listed, namely Alitta succinea (Leuckart, 1847); Arabella (Arabella) iricolor Montagu, 1804; Capitella capitata (Fabricius, 1780) complex; Exogone (Exogone) breviantennata Hartmann-Schröder, 1959; Heteromastus filiformis (Claparède, 1864); Isolda pulchella Müller, 1858; Mediomastus californiensis Hartman, 1944; Namalycastis fauveli Nageswara Rao, 1981; Namalycastis geayi (Gravier, 1901); Namalycastis senegalensis (Saint-Joseph, 1901); Nephtys simoni Perkins, 1980; Paraonis amazonica sp. n. ; Sigambra bassi (Hartman, 1945); and Sigambra grubii Müller, 1858. Among them, Namalycastis fauveli and Namalycastis geayi are recorded for the first time in Brazil. Paraonis amazonica sp. n. is a new species for science, characterized by a rounded prostomium, 4–8 pairs of foliaceous branchiae, absent eyes, and two types of modified neurochaetae, acicular and hook-shaped.
Ion diffusion and acceleration in plasma turbulence

Particle transport, acceleration and energization are phenomena of major importance for both space and laboratory plasmas. Despite years of study, an accurate theoretical description of these effects is still lacking. Validating models with self-consistent, kinetic simulations represents today a new challenge for the description of weakly collisional, turbulent plasmas. We perform simulations of steady state turbulence in the 2.5-dimensional approximation (three-dimensional fields that depend only on two-dimensional spatial directions). The chosen plasma parameters allow to span different systems, going from the solar corona to the solar wind, from the Earth’s magnetosheath to confinement devices. To describe the ion diffusion we adapted the nonlinear guiding centre (NLGC) theory to the two-dimensional case. Finally, we investigated the local influence of coherent structures on particle energization and acceleration: current sheets play an important role if the ions’ Larmor radii are of the order of the current sheet’s size. This resonance-like process leads to the violation of the magnetic moment conservation, eventually enhancing the velocity-space diffusion.
Distance Hardening in Large MIMO Systems

Asymptotic analysis plays an important role in the performance evaluation and technology design of large multiple-input multiple-output (MIMO) systems. This paper investigates an asymptotic property of large MIMO systems, called distance hardening. It involves distance metrics defined in terms of many factors, such as the channel matrix and the difference matrix of two arbitrary transmitted codewords. The asymptotic property is revealed by the use of the Chernoff bounding method and expressed in an analogous way to the well-known channel hardening. More specifically, we first derive Chernoff bounds on the tail probabilities of distance metrics, in which we are interested. Then, we formulate the asymptotic property based on a generalized definition of the hardening phenomena by referring to a formal definition of the channel hardening. The distance hardening is shown to have implications for space-time code design, MIMO detection, and millimeter wave MIMO systems. Numerical simulations are conducted to verify our theoretical development.