Miracle-dz/UniFAR-FTUs huggingface dataset:
Orthogonal space-time block coding over time-selective fading channels: a PIC detector for the H/sub i/ systems

One major assumption in all space-time block coding (STBC) schemes is that the channel remains static over the length of the codeword. However, time selective fading channels do exist, and in such case the conventional STBC detectors can suffer from a large error floor in the high signal-to-noise ratio cases. As a sequel to our previous papers on this subject, this paper aims to eliminate the error floor of the H/sub i/ coded STBC systems (i = 3 and 4) by employing the technique of parallel interference cancellation (PIC). Compared with the conventional H/sub i/ detector, the PlC detector incurs a moderately higher computational complexity, but this can be justified by the enormous performance improvement.
Work-practice changes associated with an electronic emergency department whiteboard

Electronic whiteboards are introduced at emergency departments (EDs) to improve work practices. This study investigates whether the time physicians and nurses at an ED spend in patient rooms versus at the control desk increases after the introduction of an electronic whiteboard. After using this whiteboard for four months nurses, but not physicians, spend more of their time with the patients. With the electronic whiteboard, nurses spend 28% of their time in patient rooms and physicians 20%. Importantly, the changes facilitated by the electronic whiteboard are also dependent on implementation issues, existing work practices and the clinicians’ experience. Another change in the work practices is distributed access to whiteboard information from the computers in patient rooms. A decrease in the mental workload of the coordinating nurse was envisaged but has not emerged. Achieving more changes appears to require an increase in whiteboard functionality and a firmer grip on the implementation process.
Prevalence of cerebral small-vessel disease in long-term breast cancer survivors exposed to both adjuvant radiotherapy and chemotherapy.

PURPOSE Adjuvant radiotherapy and chemotherapy for breast cancer have been related to transient ischemic attacks and stroke. To date, no studies have investigated the relationship between these adjuvant therapies and subclinical cerebral small-vessel disease in survivors of breast cancer. We compared white matter lesion (WML) volume and prevalence of brain infarctions and cerebral microbleeds (CMBs) between breast cancer survivors exposed to adjuvant radiotherapy and chemotherapy (aRCeBCSs) for primary disease and a population-based reference group. PATIENTS AND METHODS Multimodal magnetic resonance imaging (1.5 T) was performed in 187 aRCeBCSs who received primary breast cancer treatment on average more than 20 years before this study and 374 age-matched reference women without a history of cancer. WML volume was segmented using fully automated software. Experienced raters reviewed all scans for cortical infarctions, lacunar infarctions, strictly lobar CMBs, and deep/infratentorial CMBs with or without lobar CMBs. Within the aRCeBCS group, we also analyzed the association between relative radiotherapy exposure to the carotid artery and prevalence of WML volume and CMBs. RESULTS The aRCeBCS group had a higher prevalence of both total CMBs and CMBs in a deep/infratentorial region than the reference group. No between-group differences were observed in the prevalence of infarctions or WML volume. Exposure of the carotid artery to radiation was not associated with WML volume or CMBs. CONCLUSION More CMBs were found in the aRCeBCS group than in the population-based controls. These vascular lesions potentially mark cerebrovascular frailty that could partially explain the well-documented association between chemotherapy and cognitive dysfunction. No support was found for a radiotherapy-related origin of CMBs.
Processing of Sisal Fiber Reinforced Composites by Resin Transfer Molding

ABSTRACT In this paper, a linear flow model based on Darcy's law was used in the experiment to measure permeability of sisal textile. The Kozeny–Carman equation was employed to predict the permeability of sisal textile and the Kozeny constant was calculated through experimental results. Both experimental and predicted permeability values of sisal textiles were compared. Effects of fiber surface treatments and fiber volume fraction on the permeability of sisal textile were also studied in this research. Comparisons of mechanical properties of sisal-textile-reinforced composites manufactured by different processing technologies were made.
Traditional Cardiovascular Risk Factors Explain the Minority of the Variability in Carotid Plaque

Background and Purpose— Subclinical atherosclerotic plaque is an important marker of increased vascular risk. Identifying factors underlying the variability in burden of atherosclerotic carotid plaque unexplained by traditional vascular risk factors may help target novel preventive strategies. Methods— As a part of the carotid substudy of the Northern Manhattan Study (NOMAS), 1790 stroke-free individuals (mean age, 69±9; 60% women; 61% Hispanic, 19% black, 18% white) were assessed for total plaque area (TPA) burden using 2-dimensional carotid ultrasound imaging. Multiple linear regression models were constructed. Model 1 used prespecified traditional risk factors: age, sex, low-density lipoprotein cholesterol, diabetes mellitus, pack-years of smoking, blood pressure, and treatment for blood pressure; and Model 2, an addition of socioeconomic and less traditional risk factors. The contributions of the components of the Framingham heart risk score and the NOMAS Global Vascular Risk Score to the TPA were explored. Results— Prevalence of carotid plaque was 58%. Mean TPA was 13±19 mm2. Model 1 explained 19.5% of the variance in TPA burden (R2=0.195). Model 2 explained 21.9% of TPA burden. Similarly, the Framingham heart risk score explained 18.8% and NOMAS global vascular risk score 21.5% of the TPA variance. Conclusions— The variation in preclinical carotid plaque burden is largely unexplained by traditional and less traditional vascular risk factors, suggesting that other unaccounted environmental and genetic factors play an important role in the determination of atherosclerotic plaque. Identification of these factors may lead to new approaches to prevent stroke and cardiovascular disease.
Use of Multimedia Case Studies to Teach Technical Subjects: A Multiple Experimental Study

A review of “ social experiments” with adoption of multimedia-based technologies in Europe has been reported. But, there has been limited discussion on the value of multimedia instructional materials in technical disciplines. This study combines results from experiments carried out over a period of three years with multiple audiences -- IT managers, business, and engineering students -- to examine if multimedia case studies do improve perceived higher order cognitive skills and if so, what accounted for such improvements. Among all the experimental groups involved, this study found that people reported improvements in perceived higher order cognitive skills, self-reported learning, learning interest, challenges to their thought process, and learning from others.
Levels of insulin-like growth factor (IGF) binding proteins, luteinizing hormone and IGF-I receptors, and steroids in dominant follicles during the first follicular wave in cattle exhibiting regular estrous cycles.

Objectives of this study were to determine if concentrations of steroids, insulin-like growth factor -I (IGF-I), and IGF binding proteins (IGFBP) in follicular fluid and numbers of LH and IGF-I receptors change during growth of the dominant follicle. Ovarian follicular development was monitored daily via ultrasound in lactating Holstein cows. Animals underwent bilateral ovariectomy when the dominant follicle was first identified (days 4-6; estrus = day 0; early; n = 5) or when it stopped growing (days 8-12; late; n = 8). All follicles were classified as dominant (DF), large (LG; > = 6 mm in diameter, excluding DF) or small (SM; < 6 mm), follicular fluid was aspirated, and theca and granulosa cells were collected. Levels of IGFBP-2, assessed via ligand blotting, were greater (P < 0.05) in LG and SM follicles compared with DF in early cows. Levels of IGFBP-3 in follicular fluid were unaffected by follicle class. Numbers of specific 125I-hCG/LH binding sites in thecal cells were greater (P < 0.01) in DF compared with LG and SM follicles of both early and late cows. Numbers of specific 125I-hCG/LH binding sites in granulosa cells were similar for follicle sizes in early cows, but, in late cows, were greater (P < 0.01) in DF compared with SM follicles and were severalfold greater (P < 0.01) in late DF compared with early DF. Numbers of receptors for IGF-I in thecal cells were 2-fold greater (P < 0.05) in DP and LG compared with SM in late cows. Numbers of IGF-I receptors in granulosa cells were unaffected by size or growth of follicles, but were severalfold greater than in theca cells. Concentrations of estradiol were severalfold greater (P < 0.01) in DF compared with LG and SM in both early and late cows. Concentrations of androstenedione in early cows were greater (P < 0.05) in DF and SM compared with LG follicles. Concentrations of progesterone and IGF-I did not differ (P > 0.10) among follicle classes, but both were greater (P < 0.10) in late LG compared with early LG follicles. Concentrations of IGF-II in follicular fluid did not differ (P > 0.10) between early and late cows but were greater (P < 0.10) in SM than DF or LG follicles. We conclude that low amounts of IGFBP-2 and increased thecal binding sites for hCG/LH appear to be related to establishment of the dominant follicle during the first follicular wave in cattle exhibiting regular estrous cycles during late lactation.
Polydimethylsiloxane (PDMS) Sub-Micron Traps for Single-Cell Analysis of Bacteria

Microfluidics has become an essential tool in single-cell analysis assays for gaining more accurate insights into cell behavior. Various microfluidics methods have been introduced facilitating single-cell analysis of a broad range of cell types. However, the study of prokaryotic cells such as Escherichia coli and others still faces the challenge of achieving proper single-cell immobilization simply due to their small size and often fast growth rates. Recently, new approaches were presented to investigate bacteria growing in monolayers and single-cell tracks under environmental control. This allows for high-resolution time-lapse observation of cell proliferation, cell morphology and fluorescence-coupled bioreporters. Inside microcolonies, interactions between nearby cells are likely and may cause interference during perturbation studies. In this paper, we present a microfluidic device containing hundred sub-micron sized trapping barrier structures for single E. coli cells. Descendant cells are rapidly washed away as well as components secreted by growing cells. Experiments show excellent growth rates, indicating high cell viability. Analyses of elongation and growth rates as well as morphology were successfully performed. This device will find application in prokaryotic single-cell studies under constant environment where by-product interference is undesired.
Fuzzy Failure Mode and Effects Analysis Using Fuzzy Evidential Reasoning and Belief Rule-Based Methodology

The main objective of this paper is to propose a new risk priority model for prioritizing failures in failure mode and effects analysis (FMEA) on the basis of fuzzy evidential reasoning (FER) and belief rule-based (BRB) methodology. The technique is particularly intended to resolve some of the shortcomings in fuzzy FMEA (i.e., fuzzy rule-based) approaches. In the proposed approach, risk factors like occurrence (O), severity (S), and detection (D), along with their relative importance weights, are described using fuzzy belief structures. The FER approach is used to capture and aggregate the diversified, uncertain assessment information given by the FMEA team members; the BRB methodology is used to model the uncertainty, and nonlinear relationships between risk factors and corresponding risk level; and the inference of the rule-based system is implemented using the weighted average-maximum composition algorithm. The Dempster rule of combination is then used to aggregate all relevant rules for assessing and prioritizing the failure modes that have been identified in FMEA. A case study concerning an ocean going fishing vessel in a marine industry is provided and conducted using the proposed model to illustrate its potential applications and benefits.
DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids.

To study a possible differential involvement of type I and type II DNA topoisomerases in the functional and structural changes that chromatin undergoes during spermatogenesis, we have determined both enzymatic activities in chicken testis cell nuclei at successive stages of differentiation. Whereas DNA topoisomerase I varies in parallel with transcriptional activity, DNA topoisomerase II was present in both replicating, transcriptionally active chicken testis cells and nonreplicating, transcriptionally inactive late spermatids. The presence of DNA topoisomerase II activity in late spermatids and, in addition, the relative increment of drug‐induced topo‐II‐mediated DNA cleavage detected in these cells, suggest that DNA topoisomerase II might modulate the topology of DNA during the marked changes that chromatin structure undergoes in the nucleohistone‐nucleoprotamine transition at the end of the spermiogenesis and could be involved in the final organization of DNA within the nucleus of the male gamete.
University of Dundee Exploiting parallelism in coalgebraic logic programming

We present a parallel implementation of Coalgebraic Logic Programming (CoALP) in the programming language Go. CoALP was initially introduced to reflect coalgebraic semantics of logic programming, with coalgebraic derivation algorithm featuring both corecursion and parallelism. Here, we discuss how the coalgebraic semantics influenced our parallel implementation of logic programming.
Distal Shift of Arterial Pressure Wave Reflection Sites With Aging

An early return of reflected waves, the backward propagation of the arterial pressure wave from the periphery to the heart, is associated with the augmentation of central pulse pressure and cardiovascular risks. The locations of arterial pressure wave reflection, along with arterial stiffening, have a major influence on the timing of the reflected wave. To determine the influence of aging on the location of a major reflection site, arterial length (via 3D artery tracing of MRI) and central (carotid-femoral) and peripheral (femoral-ankle) pulse wave velocities were measured in 208 adults varying in age. The major reflection site was detected by carotid-femoral pulse wave velocity and the reflected wave transit time (via carotid arterial pressure wave analysis). The length from the aortic valve to the major reflection site (eg, effective reflecting length) significantly increased with aging. The effective reflecting length normalized by the arterial length demonstrated that the major reflection sites were located between the aortic bifurcation and femoral site in most of the subjects. The normalized effective reflecting length did not alter with aging until 65 years of age and increased remarkably thereafter in men and women. The effective reflecting length was significantly and positively associated with the difference between central and peripheral pulse wave velocities (r=0.76). This correlation remained significant even when the influence of aortic pulse wave velocity was partial out (r=0.35). These results suggest that the major reflection site shifts distally with aging partly because of the closer matching of impedance provided by central and peripheral arterial stiffness.
Accelerated quadratic proxy for geometric optimization

We present the Accelerated Quadratic Proxy (AQP) - a simple first-order algorithm for the optimization of geometric energies defined over triangular and tetrahedral meshes. The main stumbling block of current optimization techniques used to minimize geometric energies over meshes is slow convergence due to ill-conditioning of the energies at their minima. We observe that this ill-conditioning is in large part due to a Laplacian-like term existing in these energies. Consequently, we suggest to locally use a quadratic polynomial proxy, whose Hessian is taken to be the Laplacian, in order to achieve a preconditioning effect. This already improves stability and convergence, but more importantly allows incorporating acceleration in an almost universal way, that is independent of mesh size and of the specific energy considered. Experiments with AQP show it is rather insensitive to mesh resolution and requires a nearly constant number of iterations to converge; this is in strong contrast to other popular optimization techniques used today such as Accelerated Gradient Descent and Quasi-Newton methods, e.g., L-BFGS. We have tested AQP for mesh deformation in 2D and 3D as well as for surface parameterization, and found it to provide a considerable speedup over common baseline techniques.
Can 9q34.2 rs633862 polymorphism predict survival in epithelial ovarian cancer?

Objective Our previous genome-wide association study (GWAS) identified that the ABO rs633862 variant in chromosome 9q34.2 was associated with the risk of epithelial ovarian cancer (EOC) in Chinese Han women. The aim of the present study was to evaluate its prognostic effect on EOC. Methods A total of 669 EOC patients were enrolled for the genotyping of rs633862 variant in 9q34.2. We used Kaplan–Meier survival curves, univariate and multivariate Cox proportional hazard models to evaluate the association of rs633862 with overall survival (OS) in EOC patients. Results We found that rs633862 variant AG/GG genotypes were significantly associated with a longer OS by using univariate Cox proportional hazards regression analysis, compared with the rs633862 AA genotype (HR = 0.69, 95% CI [0.49–0.98], p = 0.035), albeit with a boardline significance in the multivariate analysis. Similar findings were observed in the subgroup of high-grade serous ovarian carcinoma. Further expression quantitative trait loci (eQTL) analysis indicated that the rs633862 AA genotype was associated with an increased level of ABO mRNA expression (p = 1.8 × 10−11). Conclusions Supplementary to the previous GWAS, our study provides additional evidence on the prognostic value of the 9q34.2 rs633862 variant in EOC patients, and this variant may function by regulating the ABO mRNA expression.
Grow & fold: compression of tetrahedral meshes

Standard representa&,ions of irregular finite element meshes combine vertex data (sample coordina&es and node values) and connectivity (tetrahedron-vertex incidence). Connectivity specifies’ how the samples should be interpolated. It may be encoded as four vertexreferences for each tetrahedron, which requires 128m bits where m is the loumber of tetrahedra in the mesh. Our ‘Grow&Fold’ format reduces the connectivity storage down to 7 bits per tetrahedron: 3 of these are used to encode the presence of children in a tetrahedron spanning tree; the other 4 constrain sequences of ‘folding’ operations, so that they produce the connectivity graph of the original mesh. Additional bits must be used for each handle in the mesh and for each topological ‘lock’ in the tree. However, as our experiments with a prototype implementation show, the increase of the storage cost due to this extra information is typically no more than l-2%. By storing vertex data in an order defined by the tree, we avoid the need to store tetrahedron-vertex references and facilitate variable length coding techniques for the vertex data. We provide the details of simple, loss-less compression and decompression algorithms.
The Cost of Diversity: The Diversification Discount and Inefficient Investment

We model the distortions that internal power struggles can generate in the allocation of resources between divisions of a diversified firm. The model predicts that if divisions are similar in the level of their resources and opportunities, funds will be transferred from divisions with poor opportunities to divisions with good opportunities. When diversity in resources and opportunities increases, however, resources can f low toward the most inefficient division, leading to more inefficient investment and less valuable firms. We test these predictions on a panel of diversified U.S. firms during the period from 1980 to 1993 and find evidence consistent with them. THE FUNDAMENTAL QUESTION IN THE THEORY of the firm, raised by Coase ~1937! more than 60 years ago, is how decisions taken inside a hierarchy differ from those taken in the marketplace. Coase suggested that decisions within a hierarchy are determined by power considerations rather than relative prices. If this is indeed the case, why, and when, does the hierarchy dominate the market? A major obstacle to progress in this area has been the lack of data. Data on internal decisions made by firms are generally proprietary. Even when they are available to researchers, it is difficult to find a comparable group of decisions taken in the market. A notable exception is the capital allocation decision in diversified firms. Since 1978, public U.S. companies have been forced to disclose their data on sales, profitability, and investments by major lines of business ~segments! An analysis of a small sample of multisegment firms reveals that segments correspond, by and large, to distinct internal
Differences in injury distribution in professional and recreational snowboarding

Introduction Little is known about the distribution of injuries in competitive snowboarding and there are no reports describing long-term complications of professional snowboarding. To examine the injury distribution and long-term impairments in active and retired professional snowboarders, a retrospective data analysis was performed using a questionnaire. As a control group, injuries of recreational snowboarders of a southern German university clinic were examined. Methods Retired and active snowboarders were identified from the result lists of the International Ski Federation (FIS) and from the current team lists of the German-speaking European national snowboard teams. After identification, a questionnaire regarding injury distribution/treatment was sent to the athletes and the filled-in questionnaires were subsequently evaluated. Injuries in recreational snowboarding were evaluated by analyzing the medical records and surgical reports for a seven-year period. Results Compared to the available literature, significantly more severe injuries that necessitated surgical treatment in recreational snowboarders were documented. Most injuries accounted for wrist fractures but also many nonunions and spinal fractures were recorded. Between active professionals, distinct differences in injury distribution were found. The number of days off differed greatly with less days in speed disciplines (35.5 days) and the maximum number of days off in snowboardcross (51 days). Injury distribution varied clearly with more injuries of the upper extremity and ankle in speed disciplines compared to snowboardcross and freestyle professionals, who exhibited more injuries to the lower extremity and head. Freestyle athletes used significantly less protectors compared to speed (P=0.01) and snowboardcross athletes (P=0.00). An analysis of retired professionals revealed a higher number of impairments in daily life and a significantly higher number of days off snowboarding (P=0.018). Conclusion Knowledge about snowboard-specific injuries is a requirement for an appropriate treatment of these patients. This first description of long-term impairments after professional snowboarding highlights the importance of the development of specific strategies to prevent daily life impairments after a professional sports career.