Miracle-dz/UniFAR-FTUs huggingface dataset:
Public opinion regarding oocyte donation in Turkey: first data from a secular population among the Islamic world.

INTRODUCTION We aimed to reveal the general attitudes of Turkish people toward various aspects of oocyte donation. METHODS This descriptive study was carried out in two separate districts of a large Turkish city. Four hundred participants were chosen by cluster sampling methods. The questionnaires were performed by 4th year medical students face to face with the participants. RESULTS The participants consisted of 232 women (58%) and 168 men (42%); 65% were married, 5% were divorced; 64% had children, 15 (4%) had infertility problems, 263 (66%) were graduates of high school or university; 269 (67%) considered themselves religious. Only less than one-third of the respondents actually knew what oocyte donation meant. Approval of oocyte donation was high in our study sample. Only 61 (15%) respondents showed complete objection to oocyte donation and more men were in favour than women. Less than half of the participants thought that their religion would prevent oocyte donation if they needed it. More than half of the participants would prefer the use of oocyte donation treatment rather than adoption of a child. CONCLUSION This is the first report on the attitudes towards oocyte donation from a country having a secular constitution and whose population is mainly Muslim. The most important conclusion to be drawn from the present study is the fact that most of the participants did not have any objection to oocyte donation treatments.
Monomorium dryhimi sp. n., a new ant species (Hymenoptera, Formicidae) of the M. monomorium group from Saudi Arabia, with a key to the Arabian Monomorium monomorium-group

Abstract A new ant species, Monomorium dryhimi, is described based on workers from a single colony collected in Al Bahah, Asir Province, Saudi Arabia. This is the fourth species of the Monomorium monomorium-group collected from Arabian Peninsula, and appears to be closely related to Monomorium holothir Bolton, 1987, from Kenya. It can be distinguished by the following characters: head in profile with a weakly convex dorsal surface and a clearly convex ventral surface; eyes of moderate size with maximum diameter EL 0.19–0.25 × HW and with 6 ommatidia in the longest row; body colour yellow to light brownish yellow. In some individuals, head and gaster slightly but conspicuously darker than rest of body. Second halves of first and second gastral tergites with two characteristic brownish transverse bands. An identification key to the workers of the Arabian species of the Monomorium monomorium-group is presented. Scanning electron micrographs are given to illustrate the new species.
Asian-American Elderly: A Review Of The Quality Of Life And Social Service Needs

This paper briefly reviews the historical, cultural and socio-economic factors that affect and define the lives of Asian-American elderly. A close examination of the present quality of life of Asian-American elderly is made to determine if there are differences between that population and other populations. This paper provides information about existing social services and a summary of culturally relevant social work intervention. In conclusion, the paper underscores the urgent need for additional data collection regarding the Asian-American elderly that will help guide appropriate policy decisions and social services for this neglected group
Mastery in Goal Scoring, T-Pattern Detection, and Polar Coordinate Analysis of Motor Skills Used by Lionel Messi and Cristiano Ronaldo

Research in soccer has traditionally given more weight to players' technical and tactical skills, but few studies have analyzed the motor skills that underpin specific motor actions. The objective of this study was to investigate the style of play of the world's top soccer players, Cristiano Ronaldo and Lionel Messi, and how they use their motor skills in attacking actions that result in a goal. We used and improved the easy-to-use observation instrument (OSMOS-soccer player) with 9 criteria, each one expanded to build 50 categories. Associations between these categories were investigated by T-pattern detection and polar coordinate analysis. T-pattern analysis detects temporal structures of complex behavioral sequences composed of simpler or directly distinguishable events within specified observation periods (time point series). Polar coordinate analysis involves the application of a complex procedure to provide a vector map of interrelated behaviors obtained from prospective and retrospective sequential analysis. The T-patterns showed that for both players the combined criteria were mainly between the different aspects of motor skills, namely the use of lower limbs, contact with the ball using the outside of the foot, locomotion, body orientation with respect to the opponent goal line, and the criteria of technical actions and the right midfield. Polar coordinate analysis detected significant associations between the same criteria included in the T-patterns as well as the criteria of turning the body, numerical equality with no pressure, and relative numerical superiority.
Rethinking Historical Trauma

Recent years have seen the rise of historical trauma as a construct to describe the impact of colonization, cultural suppression, and historical oppression of Indigenous peoples in North America (e.g., Native Americans in the United States, Aboriginal peoples in Canada). The discourses of psychiatry and psychology contribute to the conflation of disparate forms of violence by emphasizing presumptively universal aspects of trauma response. Many proponents of this construct have made explicit analogies to the Holocaust as a way to understand the transgenerational effects of genocide. However, the social, cultural, and psychological contexts of the Holocaust and of post-colonial Indigenous “survivance” differ in many striking ways. Indeed, the comparison suggests that the persistent suffering of Indigenous peoples in the Americas reflects not so much past trauma as ongoing structural violence. The comparative study of genocide and other forms of massive, organized violence can do much to illuminate both common mechanisms and distinctive features, and trace the looping effects from political processes to individual experience and back again. The ethics and pragmatics of individual and collective healing, restitution, resilience, and recovery can be understood in terms of the self-vindicating loops between politics, structural violence, public discourse, and embodied experience.
Age‐related behaviors have distinct transcriptional profiles in Caenorhabditis elegans

There has been a great deal of interest in identifying potential biomarkers of aging. Biomarkers of aging would be useful to predict potential vulnerabilities in an individual that may arise well before they are chronologically expected, due to idiosyncratic aging rates that occur between individuals. Prior attempts to identify biomarkers of aging have often relied on the comparisons of long‐lived animals to a wild‐type control. However, the effect of interventions in model systems that prolong lifespan (such as single gene mutations or caloric restriction) can sometimes be difficult to interpret due to the manipulation itself having multiple unforeseen consequences on physiology, unrelated to aging itself. The search for predictive biomarkers of aging therefore is problematic, and the identification of metrics that can be used to predict either physiological or chronological age would be of great value. One methodology that has been used to identify biomarkers for numerous pathologies is gene expression profiling. Here, we report whole‐genome expression profiles of individual wild‐type Caenorhabditis elegans covering the entire wild‐type nematode lifespan. Individual nematodes were scored for either age‐related behavioral phenotypes, or survival, and then subsequently associated with their respective gene expression profiles. This facilitated the identification of transcriptional profiles that were highly associated with either physiological or chronological age. Overall, our approach serves as a paradigm for identifying potential biomarkers of aging in higher organisms that can be repeatedly sampled throughout their lifespan.
Adult Degenerative Scoliosis Treated With XLIF: Clinical and Radiographical Results of a Prospective Multicenter Study With 24-Month Follow-up

Study Design. Prospective, multicenter, single-arm study. Objective. The objective of this study was to evaluate the clinical and radiographical results of patients undergoing extreme lateral interbody fusion (XLIF), a minimally disruptive lateral transpsoas retroperitoneal surgical approach for the treatment of degenerative scoliosis (DS). Summary of Background Data. Surgery for the treatment of DS has been reported to have acceptable results but is traditionally associated with high morbidity and complication rates. A minimally disruptive lateral transpsoas retroperitoneal surgical approach (XLIF) has become popular for the treatment of DS. This is the first prospective, multicenter study to quantify outcomes after XLIF in this patient population. Methods. A total of 107 patients with DS who underwent the XLIF procedure with or without supplemental posterior fixation at one or more intervertebral levels were enrolled in this study. Clinical and radiographical results were evaluated up to 24 months after surgery. Results. Mean patient age was 68 years; 73% of patients were female. A mean of 3.0 (range, 1–6) levels were treated with XLIF per patient. Overall complication rate was low compared with traditional surgical treatment of DS. Significant improvement was seen in all clinical outcome measures at 24 months: Oswestry Disability Index, visual analogue scale for back pain and leg pain, and 36-Item Short Form Health Survey mental and physical component summaries (P < 0.001). Eighty-five percent of patients were satisfied with their outcome and would undergo the procedure again. In patients with hypolordosis, lumbar lordosis was corrected from a mean of 27.7° to 33.6° at 24 months (P < 0.001). Overall Cobb angle was corrected from 20.9° to 15.2°, with the greatest correction observed in patients supplemented with bilateral pedicle screws. Conclusion. This study demonstrates the use of the XLIF procedure in the treatment of DS. XLIF is associated with good clinical and radiographical outcomes, with a substantially lower complication rate than has been reported with traditional surgical procedures. Level of Evidence: 3
Guiltless Gluttony: The Asymmetric Effect of Size Labels on Size Perceptions and Consumption

Size labels adopted by food vendors can have a major impact on size judgments and consumption. In forming size judgments, consumers integrate the actual size information from the stimuli with the semantic cue from the size label. Size labels influence not only size perception and actual consumption, they also affect perceived consumption. Size labels can also result in relative perceived size reversals, so that consumers deem a smaller package to be bigger than a larger one. Further, consumers are more likely to believe a label that professes an item to be smaller (vs. larger) in the size range associated with that item. This asymmetric effect of size labels can result in larger consumption without the consumer even being aware of it ("guiltless gluttony").
Differences in Computer Use of Practicing versus Preservice Teachers

AbstractThis study compared levels of computer use by practicing teachers with expected levels of use by preservice teachers. The variables related to computer use were also measured. The levels of computer use of practicing (N = 170) and preservice (N = 167) elementary school teachers were first classified. The predictiveness of several personal variables to the use of available computers for teaching was then examined. Participants completed questionnaires that assessed level of computer use, self-competence in the use of computers, perceived relevance of computers to teaching, teacher locus of control, and innovativeness. Data on age, gender, and years of computer experience were also collected. Chi-square and logistic regression procedures were used to analyze the differences between the groups’ levels of use and relationships between teacher characteristics and computer use, respectively. About half of the practicing teachers reported not using computers for teaching. Almost all of the preservice tea.
A Review of Accelerometry-Based Wearable Motion Detectors for Physical Activity Monitoring

Characteristics of physical activity are indicative of one’s mobility level, latent chronic diseases and aging process. Accelerometers have been widely accepted as useful and practical sensors for wearable devices to measure and assess physical activity. This paper reviews the development of wearable accelerometry-based motion detectors. The principle of accelerometry measurement, sensor properties and sensor placements are first introduced. Various research using accelerometry-based wearable motion detectors for physical activity monitoring and assessment, including posture and movement classification, estimation of energy expenditure, fall detection and balance control evaluation, are also reviewed. Finally this paper reviews and compares existing commercial products to provide a comprehensive outlook of current development status and possible emerging technologies.
Mode of Action: Oxalate Crystal-Induced Renal Tubule Degeneration and Glycolic Acid-Induced Dysmorphogenesis—Renal and Developmental Effects of Ethylene Glycol

Ethylene glycol can cause both renal and developmental toxicity, with metabolism playing a key role in the mode of action (MOA) for each form of toxicity. Renal toxicity is ascribed to the terminal metabolite oxalic acid, which precipitates in the kidney in the form of calcium oxalate crystals and is believed to cause physical damage to the renal tubules. The human relevance of the renal toxicity of ethylene glycol is indicated by the similarity between animals and humans of metabolic pathways, the observation of renal oxalate crystals in toxicity studies in experimental animals and human poisonings, and cases of human kidney and bladder stones related to dietary oxalates and oxalate precursors. High-dose gavage exposures to ethylene glycol also cause axial skeletal defects in rodents (but not rabbits), with the intermediary metabolite, glycolic acid, identified as the causative agent. However, the mechanism by which glycolic acid perturbs development has not been investigated sufficiently to develop a plausible hypothesis of mode of action, nor have any cases of ethylene glycol-induced developmental effects been reported in humans. Given this, and the variations in sensitivity between animal species in response, the relevance to humans of ethylene glycol-induced developmental toxicity in animals is unknown at this time.
German Cities and Bourgeois Modernism, 1890-1924

1. Introduction 2. The Sense of Time: Configuring History and Memory in the City 3. The Sense of Place: Representing the Local in the Modern City 4. Nature and Culture: Greening the City 5. The Designed Object: Commercial Culture and the Global Market 6. Liberal Governmentality and the Spatial Politics of 'Burgerlichkeit' 7. Conclusion & Epilogue: Bourgeois Modernism and National Socialism
Identification of a basal-like subtype and comparative effect of epirubicin-based chemotherapy and sequential epirubicin followed by docetaxel chemotherapy in the PACS 01 breast cancer trial: 33 markers studied on tissue-microarrays (TMA).

509 Background: Immunohistochemical profiling studies with TMA classified breast cancer by luminal, normal breast like, HER-2 overexpressing, and basal-like subtypes. The aim of this study was to evaluate the impact of these subclasses in terms of therapeutic benefit for patients (pts) with node positive operable breast cancer included in the phase III trial PACS01. METHODS Among the 1999 pts randomized, 1100 paraffin blocs were collected for TMA. Pts were treated with either arm A: 6 cycles of FEC100 (546 pts) or arm B: docetaxel 100 mg/m2 replaced FEC100 for the last 3 cycles (554 pts). The median follow up was 5 years. The 33 analysed markers explored different pathways: cellular differentiation (CK5/6,8/18,14, P-Cadherin, E-cadherin, α-catenin, β-catenin, AF6, MUC1, Cav1, moesin, Cd10, CD44), proliferation/apoptosis (AuroraA, Tacc2/3, Ki67, CyclinD1, Bcl2, p21, p27), ER related (ER, PR, Gata3), and oncogene/ antioncogene (P53, HER2, EGFR1, Pten, Cmet, Fhit, FGFR, Angiogenin, topoisomeraseIIα). All antibodies were evaluated in quick score. RESULTS In terms of metastases free survival (MFS) 16 markers harboured a statistical significant value under 20%. The hierarchical clustering for 80% of complete data, identify a cluster of pts (n=531) characterized by the positive expression of EGFR1, Moesin, Pcadherin, and p53, considered as basal-like subtype (BLST). This cluster presented a pejorative predictive value both in Log-rank test (LR) (p=0.002) and in Cox multivariate analysis (HR=0.65; p=0.009), confirmed in overall survival (OS) (LR p<0.0001; cox HR=0.46, p<0.001). BLST pts had a significantly better MFS (LR p=0.05) in the arm B, confirmed in OS (LR p=0.005), as for a more theoretical basal signature and ER negativity (LR MFS p=0.0033, OS p=0.0052; cox MFS HR=0.71 p=0.04, OS HR=0.51 p=0.003). For a second cluster considered as luminal subtype (ER positive and BLST parameters negatives) no difference was observed whatever the arm. CONCLUSIONS The basal-like profile identified in this study is significantly associated to a worst prognostic, but also to a better response to sequential FEC/docetaxel chemotherapy. [Table: see text].
Electric Field Sensing For Graphical Interfaces

The earliest bit-mapped graphical computers have progressed to bring real-time 3D rendering and digital video to the desktop, but the common physical interface remains unchanged from the first workstations. As a result, many applications, such as modeling or navigating in virtual worlds, are often limited not by processing speed but by the users' difficulty in conveying desired actions to the computer. We outline the theory and implementation of low-frequency electric fields as sensing techniques, then present a range of applications developed for interacting with computer graphics.
High-Quality Factor Superconducting Flexible Resonators Embedded in Thin-Film Polyimide HD-4110

We present the design, fabrication procedure, and measurement results of Nb superconducting microstrip transmission line resonators fabricated using thin-film polyimide HD-4110, including both nonembedded and embedded versions. These resonators were used to characterize the microwave dielectric loss tangent of 20 <inline-formula> <tex-math notation="LaTeX">$\mu$</tex-math></inline-formula>m thick polyimide HD-4110 at deep cryogenic temperatures. We observed high-quality factors (<italic>Q</italic>) up to 21 040 at 1.2 K in the frequency range of 2–21 GHz for nonembedded resonators, indicating that the dielectric loss tangent can be less than 5<inline-formula> <tex-math notation="LaTeX">$\times$</tex-math></inline-formula>10<sup>−5</sup>. Embedded resonators with an additional 20 <inline-formula><tex-math notation="LaTeX">$\mu$</tex-math></inline-formula>m thick encapsulation layer also exhibited <italic>Q</italic> values as high as <inline-formula><tex-math notation="LaTeX">$\sim 19$ </tex-math></inline-formula>200. Dielectric and conductor (quasiparticle) loss have been compared between the two types of resonators. This study provides information applicable to the design of future high-density, flexible, multilayer superconducting cables, which are of great interest for potential applications in cryogenic electronics systems, including quantum computers.
Caffeine Affects Cardiovascular and Neuroendocrine Activation at Work and Home

Objective This study investigated the effects of moderate doses of caffeine on ambulatory blood pressure and heart rate, urinary excretion of epinephrine, norepinephrine, and cortisol, and subjective measures of stress during normal activities at work and at home in the evening. Methods Healthy, nonsmoking, habitual coffee drinkers (N = 47) participated in 3 days of ambulatory study. After a day of ad lib caffeine consumption, caffeine (500 mg) and placebo were administered double-blind in counter-balanced order on separate workdays. Ambulatory blood pressure and heart rate were monitored from the start of the workday until bedtime. Urinary excretion of catecholamines and cortisol was assessed during the workday and evening. Results Caffeine administration significantly raised average ambulatory blood pressure during the workday and evening by 4/3 mm Hg and reduced average heart rate by 2 bpm. Caffeine also increased by 32% the levels of free epinephrine excreted during the workday and the evening. In addition, caffeine amplified the increases in blood pressure and heart rate associated with higher levels of self-reported stress during the activities of the day. Effects were undiminished through the evening until bedtime. Conclusions Caffeine has significant hemodynamic and humoral effects in habitual coffee drinkers that persist for many hours during the activities of everyday life. Furthermore, caffeine may exaggerate sympathetic adrenal-medullary responses to the stressful events of normal daily life. Repeated daily blood pressure elevations and increases in stress reactivity caused by caffeine consumption could contribute to an increased risk of coronary heart disease in the adult population.
Xanthone from Garcinia eugenifolia (Clusiaceae)

Studies on the twigs of Garcinia eugenifolia have led to the isolation of one xanthone 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6(2H)-one (1) and one triterpenoid, sitosterol (2). Meanwhile, studies on the leaves of Garcinia eugenifolia provided another triterpenoid, friedelin (3). The structures of these compounds were determined by spectroscopic methods such as 1H NMR, 13C NMR, mass spectrometry (MS) and by comparison with previous studies. The hexane and ethyl acetate extracts of Garcinia eugenifolia indicated strong cytotoxicity towards the HL-60 cell line with IC50 values of 1.9 µg/ml and 2.5 µg/ml respectively. However, the methanol extract gave moderate inhibitory activities (IC50&#60;10 µg/ml) towards HL-60 cell line.
Seismic tomography of compressional wave attenuation structure for Kı̄lauea Volcano, Hawai‘i

We present a frequency‐independent three‐dimensional (3‐D) compressional wave attenuation model (indicated by the reciprocal of quality factor Qp) for Kı̄lauea Volcano in Hawai‘i. We apply the simul2000 tomographic algorithm to the attenuation operator t* values for the inversion of Qp perturbations through a recent 3‐D seismic velocity model and earthquake location catalog. The t* values are measured from amplitude spectra of 26708 P wave arrivals of 1036 events recorded by 61 seismic stations at the Hawaiian Volcanology Observatory. The 3‐D Qp model has a uniform horizontal grid spacing of 3 km, and the vertical node intervals range between 2 and 10 km down to 35 km depth. In general, the resolved Qp values increase with depth, and there is a correlation between seismic activity and low‐Qp values. The area beneath the summit caldera is dominated by low‐Qp anomalies throughout the entire resolved depth range. The Southwest Rift Zone and the East Rift Zone exhibit very high Qp values at about 9 km depth, whereas the shallow depths are characterized with low‐Qp anomalies comparable with those in the summit area. The seismic zones and fault systems generally display relatively high Qp values relative to the summit. The newly developed Qp model provides an important complement to the existing velocity models for exploring the magmatic system and evaluating and interpreting intrinsic physical properties of the rocks in the study area.