Miracle-dz/UniFAR-FTUs huggingface dataset:
New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: the European Registry of Endovascular Aortic Repair Complications.

OBJECTIVES To review the incidence, clinical presentation, definite management and 1-year outcome in patients with aorto-oesophageal fistulation (AOF) following thoracic endovascular aortic repair (TEVAR). METHODS International multicentre registry (European Registry of Endovascular Aortic Repair Complications) between 2001 and 2011 with a total caseload of 2387 TEVAR procedures (17 centres). RESULTS Thirty-six patients with a median age of 69 years (IQR 56-75), 25% females and 9 patients (19%) following previous aortic surgery were identified. The incidence of AOF in the entire cohort after TEVAR in the study period was 1.5%. The primary underlying aortic pathology for TEVAR was atherosclerotic aneurysm formation in 53% of patients and the median time to development of AOF was 90 days (IQR 30-150). Leading clinical symptoms were fever of unknown origin in 29 (81%), haematemesis in 19 (53%) and shock in 8 (22%) patients. Diagnosis could be confirmed via computed tomography in 92% of the cases with the leading sign of a new mediastinal mass in 28 (78%) patients. A conservative approach resulted in a 100% 1-year mortality, and 1-year survival for an oesophageal stenting-only approach was 17%. Survival after isolated oesophagectomy was 43%. The highest 1-year survival rate (46%) could be achieved via an aggressive treatment including radical oesophagectomy and aortic replacement [relative risk increase 1.73 95% confidence interval (CI) 1.03-2.92]. The survival advantage of this aggressive treatment modality could be confirmed in bootstrap analysis (95% CI 1.11-3.33). CONCLUSIONS The development of AOF is a rare but lethal complication after TEVAR, being associated with the need for emergency TEVAR as well as mediastinal haematoma formation. The only durable and successful approach to cure the disease is radical oesophagectomy and extensive aortic reconstruction. These findings may serve as a decision-making tool for physicians treating these complex patients.
Historiography for accounting : Methodological contributions, contributors and thought patterns from 1983 to 2012

Purpose - – The purpose of this paper is to examine the historiographic writings for accounting concerned with the craft of researching and writing history, published in the English-language, across a period of 30 years from 1983 to 2012. The study's aim is three-fold: first, to review the literature pertaining to the writing of accounting history and to identify key developments and trends; second, to identify the contributors to this literature and their publication outlets and third, to analyze citations to identify individuals or groups who have gained traction in accounting historiography. Design/methodology/approach - – An essay focusing on developments in the accounting historiography literature as well as a review of some key thoughts or issues in present-day accounting historiography. Findings - – The study shows that a key development in the accounting historiography literature during this period has been the advent of new accounting history, which has contributed much theoretical and topical diversity in historical accounting research and an acceptance of the role of oral history as a means of expanding the archive. Research limitations/implications - – The present study, with its focus on contributions on the craft of researching and writing history, does not itself examine actual research studies which have been undertaken on accounting's past across the same period of time. Originality/value - – The study may assist in making the contributions examined more generally assessable and comprehensible to researchers to both explore and re-explore and may even contribute to the development of further contributions on accounting historiography to guide the approaches to, and direction of, historical accounting research in future.
Recent advances of sonodynamic therapy in cancer treatment

Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeply into tissues and can be focused into a small region of a tumor to activate a sonosensitizer which offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. In this article, we critically reviewed the currently accepted mechanisms of sonodynamic action and summarized the classification of sonosensitizers. At the same time, the breath of evidence from SDT-based studies suggests that SDT is promising for cancer treatment.
Human Papillomavirus Infection and its Vaccines: Knowledge and Attitudes of Primary Health Clinic Nurses in Kelantan, Malaysia.

BACKGROUND Cervical cancer though preventable is still the leading cause of cancer death among women secondary to breast cancer. Persistent infection with HPV has been causally linked to the disease. A school based HPV vaccination program was introduced in late 2010 in Malaysia and nurse support is essential for its success. OBJECTIVES To determine nurses knowledge and attitudes about HPV infection and its vaccines, and factors associated with their knowledge. MATERIALS AND METHODS This cross-sectional study was conducted among nurses working at primary health clinics in Kelantan from mid-June till the end of July 2014. Its involved 330 nurses selected through multistage random sampling. A validated self-administered questionnaire consisting of 11 items for the knowledge domain and eight items for the attitude domain was used. RESULTS The response rate of the study was 93.7%. The mean knowledge and mean attitude (SD) scores were 5.37 (1.76) and 29.8 (3.51) respectively. Only 24% knew that HPV is the most common sexually transmitted infection and 67% correctly answered that Gardasil vaccine can protect against four types of HPV. Nearly 60% of participants wrongly answered that HPV vaccines cannot be offered to sexually active women. Likewise, 70.9% participants were not aware that HPV vaccine may be appropriate for females aged 9 through 26 years. Though 90% of participants believed that the vaccine is safe, nearly half of them were unsure about efficacy. From multiple linear regression analysis, among the factors tested only participant's level of education showed a statistically significant association with the HPV knowledge score (<0.001). CONCLUSIONS This study indicates nurses have favorable attitudes towards HPV vaccination; however they have significant knowledge deficit and major misunderstanding in critical knowledge items. Among the factors tested, nursing qualification is the only factor that is significantly associated with the nurses knowledge score.
Sharp Bounds for the Tails of Functionals of Markov Chains

This paper is devoted to establishing sharp bounds for deviation probabilities of partial sums $\sum_{i=1}^{n}f(X_{i})$, where $X=(X_{n})_{n\in{\bf N}}$ is a positive recurrent Markov chain and f is a real valued function defined on its state space. Combining the regenerative method to the Esscher transformation, these estimates are shown in particular to generalize probability inequalities proved in the independent i.i. d. case to the Markovian setting for (not necessarily uniformly) geometrically ergodic chains.
Validation and psychometric evaluation of the Hungarian version of the Short Health Anxiety Inventory (SHAI)

Elmeleti hatter es celkitűzes: Jelen kutatas celja a Roviditett Egeszsegszorongas-kerdőiv (Short Health Anxiety Inventory — SHAI; Salkovskis, Rimes, Warwick, & Clark, 2002) magyar verziojanak elkeszitese, pszichometriai ertekelese es kerdőives validalasa volt. Modszerek: A vizsgalatban 441 alsoeves egyetemista (37% ferfi; atlageletkor: 20,5±1,33 ev) vett reszt, osszesen 5 kerdőiv kitoltesevel (SHAI; Szomatoszenzoros Amplifikacio — SSAS; Vonasszorongas — STAI-T; Szubjektiv Testi Tunetek — PHQ-15; WHO Jol-let — WBI-5). Eredmenyek: A megerősitő faktorelemzes mind a ket-, mind a haromfaktoros verzio eseteben jo illeszkedesi mutatokat eredmenyezett, ezert az irodalomban inkabb elfogadott ket alskalas (Betegge valas eszlelt valoszinűsege; Betegseg eszlelt kovetkezmenye) megoldas hasznalatat javasoljuk. A kerdőiv magyar verzioja jo belső konzisztenciaval (Cronbach-alfa = 0,83) birt, a STAI-T, az SSAS es a PHQ-15 skalakkal kozepes erőssegű (Pearson-r: 0,33—0,44; p<0,001) korrelaciot mutatott, mig a WBI-5 eseteben.
The SigB s Factor Regulates Multiple Salt Acclimation Responses of the Cyanobacterium Synechocystis

Changing of principal s factor in RNA polymerase holoenzyme to a group 2 s factor redirects transcription when cyanobacteria acclimate to suboptimal environmental conditions. The group 2 sigma factor SigB was found to be important for the growth of the cyanobacterium Synechocystis sp. PCC 6803 in high-salt (0.7 M NaCl) stress but not in mild heat stress at 43C although the expression of the sigB gene was similarly highly, but only transiently up-regulated at both conditions. The SigB factor was found to regulate many salt acclimation processes. The amount of glucosylglycerol-phosphate synthase, a key enzyme in the production of the compatible solute glucosylglycerol, was lower in the inactivation strain DsigB than in the control strain. Addition of the compatible solute trehalose almost completely restored the growth of the DsigB strain at 0.7 M NaCl. High-salt conditions lowered the chlorophyll and phycobilin contents of the cells while protective carotenoid pigments, especially zeaxanthin and myxoxanthophyll, were up-regulated in the control strain. These carotenoids were up-regulated in the DsigCDE strain (SigB is the only functional group 2 s factor) and down-regulated in the DsigB strain under standard conditions. In addition, the HspA heat shock protein was less abundant and more abundant in the DsigB and DsigCDE strains, respectively, than in the control strain in high-salt conditions. Some cellular responses are common to heat and salt stresses, but pretreatment with mild heat did not protect cells against salt shock although protection against heat shock was evident. Different cyanobacterial species have adapted to ecological niches varying from fresh water to hypersaline environments. Research of salt acclimation is important because large-scale cultivation of cyanobacteria, for example for bioenergy production, would best occur in brackish water or seawater, as fresh water supplies of the Earth are limited. Salt acclimation processes in cyanobacteria are already fairly well known (for recent review, see Hagemann, 2011) but the sensing and transmission of salt signals are not yet well understood. Salt stress acclimation and signaling processes are best characterized in a model cyanobacterium Synechocystis sp. strain PCC 6803 (hereafter Synechocystis). Synechocystis is a unicellular, nontoxic, nonnitrogenfixing freshwater cyanobacterium that is moderately
Hybrid EEG–fNIRS-Based Eight-Command Decoding for BCI: Application to Quadcopter Control

In this paper, a hybrid electroencephalography–functional near-infrared spectroscopy (EEG–fNIRS) scheme to decode eight active brain commands from the frontal brain region for brain–computer interface is presented. A total of eight commands are decoded by fNIRS, as positioned on the prefrontal cortex, and by EEG, around the frontal, parietal, and visual cortices. Mental arithmetic, mental counting, mental rotation, and word formation tasks are decoded with fNIRS, in which the selected features for classification and command generation are the peak, minimum, and mean ΔHbO values within a 2-s moving window. In the case of EEG, two eyeblinks, three eyeblinks, and eye movement in the up/down and left/right directions are used for four-command generation. The features in this case are the number of peaks and the mean of the EEG signal during 1 s window. We tested the generated commands on a quadcopter in an open space. An average accuracy of 75.6% was achieved with fNIRS for four-command decoding and 86% with EEG for another four-command decoding. The testing results show the possibility of controlling a quadcopter online and in real-time using eight commands from the prefrontal and frontal cortices via the proposed hybrid EEG–fNIRS interface.
Are older workers more active copers? Longitudinal effects of age‐contingent coping on strain at work

Summary This study addresses coping processes as explanation of age-related differences in strain experience. Based on the life-span theory of control, we posit that older workers employ more active problem-focused and more active emotion-focused coping strategies than younger workers, which should mediate age effects on strain at work. The correlation between age and passive avoidance coping, in contrast, is expected to be qualified by external resources such as job control. Hypotheses were tested in a two-wave panel study (8 months lag) with 634 workers (age range 16–65 years). Job demands were considered as control variables. As predicted, older as compared with younger workers reported more active problem-focused coping, which mediated age differences on strain in the longitudinal analysis. No mediation was found for active emotion-focused coping. Moreover, age-contingent effects of passive avoidance coping were moderated by job control. When job control was low, younger as compared with older workers reported more avoidance coping, which in turn decreased strain in the longitudinal analysis. Finally, reverse longitudinal effects of age-contingent strain on active problem-focused and active emotion-focused coping provide initial evidence for age-contingent resource spirals. Together, the results reveal specific strengths of older workers for stress management at work. Copyright © 2015 John Wiley & Sons, Ltd.
Correction of confounding bias in non‐randomized studies by appropriate weighting

In non‐randomized studies, the assessment of a causal effect of treatment or exposure on outcome is hampered by possible confounding. Applying multiple regression models including the effects of treatment and covariates on outcome is the well‐known classical approach to adjust for confounding. In recent years other approaches have been promoted. One of them is based on the propensity score and considers the effect of possible confounders on treatment as a relevant criterion for adjustment. Another proposal is based on using an instrumental variable. Here inference relies on a factor, the instrument, which affects treatment but is thought to be otherwise unrelated to outcome, so that it mimics randomization. Each of these approaches can basically be interpreted as a simple reweighting scheme, designed to address confounding. The procedures will be compared with respect to their fundamental properties, namely, which bias they aim to eliminate, which effect they aim to estimate, and which parameter is modelled. We will expand our overview of methods for analysis of non‐randomized studies to methods for analysis of randomized controlled trials and show that analyses of both study types may target different effects and different parameters. The considerations will be illustrated using a breast cancer study with a so‐called Comprehensive Cohort Study design, including a randomized controlled trial and a non‐randomized study in the same patient population as sub‐cohorts. This design offers ideal opportunities to discuss and illustrate the properties of the different approaches.
Health Policy and Practice

RESULTS: The annual numbers of procedures were approximately 10%–15% lower than those in a comparison survey with a good response rate. The annual number of RVUs per full-time equivalent (FTE) diagnostic radiologist was highly variable in every group category, as was the number of RVUs per clinical work hour. Multivariate regression analysis indicated that variation in the annual number of hours worked did not explain variation in annual workload. RVUs per FTE radiologist were higher the greater the percentage of a group’s workload from interventional, computed tomographic, and magnetic resonance imaging procedures.
Characterization of human follicular thyroid cancer cell lines in preclinical mouse models

Follicular thyroid cancer (FTC) is the second most common type of thyroid cancers. In order to develop more effective personalized therapies, it is necessary to thoroughly evaluate patient-derived cell lines in in vivo preclinical models before using them to test new, targeted therapies. This study evaluates the tumorigenic and metastatic potential of a panel of three human FTC cell lines (WRO, FTC-238, and TT1609-CO2) with defined genetic mutations in two in vivo murine models: an orthotopic thyroid cancer model to study tumor progression and a tail vein injection model to study metastasis. All cell lines developed tumors in the orthotopic model, with take rates of 100%. Notably, WRO-derived tumors grew two to four times faster than tumors arising from the FTC-238 and TT2609-CO2 cell lines. These results mirrored those of a tail vein injection model for lung metastasis: one hundred percent of mice injected with WRO cells in the tail vein exhibited aggressive growth of bilateral lung metastases within 35 days. In contrast, tail vein injection of FTC-238 or TT2609-CO2 cells did not result in lung metastasis. Together, our work demonstrates that these human FTC cell lines display highly varied tumorigenic and metastatic potential in vivo with WRO being the most aggressive cell line in both orthotopic and lung metastasis models. This information will be valuable when selecting cell lines for preclinical drug testing.
An international profile of industry-relevant competencies and skill gaps in modern graduates

At a time when graduates are increasingly being relied upon to add value and foster innovative practice in organisations, concerns for the impact of an endemic graduate skills gap are growing. Higher education institutions (HEIs) are consistently blamed for soft skill deficiencies and many are now pursuing policies on the development of generic skills. This paper unpacks the concept of graduate employability by presenting a table of industry-relevant competencies, including assigned definitions and empirical assessments of their relative importance, identified by employers internationally over the past ten years. Findings articulate what businesses need from today's graduates and depict the nature and extent of graduate skill gaps worldwide. They also confirm an extensive and confusing range of definitions assigned to individual competencies, validating concerns for current graduate employability policies and calling for a fresh approach to profiling industry's requirements of the modern graduate.
Perceived maternal and paternal psychological control by Ethiopian adolescents

The study primarily aimed to investigate the association between adolescents’ perception of parental psychological control and the adolescents’ self-esteem, school adjustment and depressive symptoms. Data were collected from 809 adolescents (females = 381 & males = 428; mean age = 16.8 years, SD = 1.58 years) from Ethiopian public schools. The data were analysed for differences in perceptions of parental control by gender. Results suggest higher perceived level of parental control to be associated with comparatively lower self-esteem and school adjustment as well as higher depressive symptoms in boys rather than girls. Gender equitable use of psychological control likely will result in positive social outcomes for adolescents.
Tsallis Entropy for Geometry Simplification

This paper presents a study and a comparison of the use of different information-theoretic measures for polygonal mesh simplification. Generalized measures from Information Theory such as Havrda–Charvat–Tsallis entropy and mutual information have been applied. These measures have been used in the error metric of a surfaces implification algorithm. We demonstrate that these measures are useful for simplifying three-dimensional polygonal meshes. We have also compared these metrics with the error metrics used in a geometry-based method and in an image-driven method. Quantitative results are presented in the comparison using the root-mean-square error (RMSE).
The spectrum of mutations causing end‐plate acetylcholinesterase deficiency

The end‐plate species of acetylcholinesterase (AChE) is an asymmetric enzyme consisting of a collagenic tail subunit composed of three collagenic strands (ColQ), each attached to a tetramer of the T isoform of the catalytic subunit (AChET) via a proline‐rich attachment domain. The principal function of the tail subunit is to anchor asymmetric AChE in the synaptic basal lamina. Human end‐plate AChE deficiency was recently shown to be caused by mutations in COLQ. We here report nine novel COLQ mutations in 7 patients with end‐plate AChE deficiency. We examine the effects of the mutations on the assembly of asymmetric AChE by coexpressing each genetically engineered COLQ mutant with ACHET in COS cells. We classify the newly recognized and previously reported COLQ mutations into four classes according to their position in ColQ and their effect on AChE expression. We find that missense mutations in the proline‐rich attachment domain abrogate attachment of catalytic subunits, that truncation mutations in the ColQ collagen domain prevent the assembly of asymmetric AChE, that hydrophobic missense residues in the C‐terminal domain prevent triple helical assembly of the ColQ collagen domain, and that other mutations in the C‐terminal region produce asymmetric species of AChE that are likely insertion incompetent. Ann Neurol 2000;47:162–170.
Emotional force of languages in multilingual speakers in Finland

ABSTRACT The aim of the present study was to investigate whether the better recall of emotional words applies to both native and later-learned languages. In a mixed design, 41 native Finnish speakers, who were substantially less proficient in their later-learned languages, which were English (second language) and Swedish (third language), were shown negative/taboo, positive, and neutral words in the three languages. Their memory for the words was assessed in an unexpected free recall test preceded by a depth of processing task (deep or shallow). The results revealed that an emotion-word advantage was visible for negatively valenced words (negative/taboo) in the native language, Finnish, and the second language, English. However, the nature of the processing task had no significant effect on recall. Additional self-report measures indicated that English was perceived as more emotional and more frequently used than Swedish. These results suggest that the amount and frequency of everyday exposure to a particular language are two critical factors in determining the degree of emotionality of that language for the speaker.
Condom Communication: Reports of Sexually Active Young Adults’ Recent Messages With New Partners

The incidence of sexually transmitted infections is high, with recent estimates suggesting 110 million cases (CDC, 2013b). A key method to reducing the risk for sexually transmitted infections is the use of a condom. Consequently, this inquiry aimed to describe the content of and reactions to condom communication. Results revealed the following condom conversation strategies: condom possession, condom exploration, condom demand, and health concerns. Results both support and challenge previous condom studies, therefore extending and informing this line of research. Data further describe reactions to condom conversations and reasons for not having a condom conversation. Findings provide tangible evidence to be used in the training of sexually active young adults.