Miracle-dz/UniFAR-FTUs huggingface dataset:
Perfectionism and Creative Strivings.

Samples of gifted children in Louisiana (N = 44) and Connecticut (N = 34) were administered the Multidimensional Perfectionism Scale (MPS) and the Khatena-Torrance Creative Perception Inventory (KTCPI). The KTCPI consisted of two biographical measures, the Something About Myself (SAM) and What Kind of Person Are You (WKOPAY) subtests. The results for the WKOPAY were generally consistent with predictions. Higher scores on the scales of the MPS associated with neurotic perfectionism, the Overall MPS, Doubts About Actions (D), Organization (O), and Parental Criticism (PC), were associated with lower scores on the WKOPAY. Inconsistent with predictions, the Concern over Mistakes (CM) and Personal Standards (PS) scales of the MPS were not significantly correlated with the WKOPAY. Results for the SAM were inconsistent with predictions, with the exception of the significant positive correlation between the PS scale and the SAM.
An Enhancer of the IL-7 Receptor α-Chain Locus Controls IL-7 Receptor Expression and Maintenance of Peripheral T Cells

The IL-7R plays critical roles in lymphocyte development and homeostasis. Although IL-7R expression is strictly regulated during lymphocyte differentiation and the immune response, little is known regarding its in vivo regulation. To address this issue, we established a mouse line with targeted deletion of the conserved non-coding sequence 1 (CNS1) element found 3.6 kb upstream of the IL-7Rα promoter. We report that IL-7Rα is expressed normally on T and B cells in thymus and bone marrow of CNS1−/− mice except for in regulatory T cells. In contrast, these mice show reduced IL-7Rα expression in conventional CD4 and CD8 T cells as well as regulatory T, NKT, and γδ T cells in the periphery. CD4 T cells of CNS1−/− mice showed IL-7Rα upregulation in the absence of growth factors and IL-7Rα downregulation by IL-7 or TCR stimulation, although the expression levels were lower than those in control mice. Naive CD4 and CD8 T cells of CNS1−/− mice show attenuated survival by culture with IL-7 and reduced homeostatic proliferation after transfer into lymphopenic hosts. CNS1−/− mice exhibit impaired maintenance of Ag-stimulated T cells. Furthermore, IL-7Rα upregulation by glucocorticoids and TNF-α was abrogated in CNS1−/− mice. This work demonstrates that the CNS1 element controls IL-7Rα expression and maintenance of peripheral T cells, suggesting differential regulation of IL-7Rα expression between central and peripheral lymphoid organs.
Periodization and planning of psychological preparation in elite combat sport programs: The case of judo

Abstract Training theories of athletes stress that training programs should be comprised of three critical phases: preparatory, competition, and transition. Physical, technical, tactical, and psychological preparations are present in each training phase. To achieve a high level of proficiency, an effective interaction among these preparations should exist within each of the critical phases of a training program. In this article a thorough examination of the four preparations within each of the three phases is provided. It is argued that any psychological intervention introduced to elite athletes during their training should reflect the aims of each critical phase of the program, and that psychological preparation should be linked to the physical, technical, and tactical preparations of the particular training practices. The combat sport of judo was selected to demonstrate how sport psychology preparation can be effectively integrated into the physical, technical, and tactical preparations of the training program within the preparatory, competition, and transition phases.
Towards a Second‐language Model of Learning in Problematic Social Contexts: the case of Arabs learning Hebrew in Israel

Abstract This article discusses the difficulty of bilingual Arab children in Israel learning Hebrew, this being the language of conflict. It is suggested that since the Israeli‐Arab social context is problematic, and does not easily permit social interaction between Israeli‐Arab minority children and Israeli‐Jewish majority children, the Hebrew curriculum for Arab children should be based on materials drawn from Arab culture. These materials are referred to as ‘culture‐based curriculum texts’. It is assumed that these texts are more interesting, comprehensible, and familiar for Israeli‐Arab learners of Hebrew than those currently used, and that they will elicit more positive attitudes to Hebrew‐learning situations. To illustrate this approach a second language reading model for problematic social contexts is presented based on the following concepts: schemata, interestingness, comprehensibility, instrumental and integrative motivation, meta‐cognition, and emotions. The model and its practical implications.
The Motivational Effects of Diminished Self-Esteem for Employees Who Experience Abusive Supervision

This research considers two theoretical perspectives on employees’ motivation associated with diminished self-esteem from abusive supervision. The self-defense view of diminished self-esteem suggests that abusive supervision motivates destructive behavior in an attempt to reassert personal control and protect victims’ self-image. The self-presentational view of diminished self-esteem suggests abusive supervision motivates behavior that attempts to signal fit with and value to the workgroup and organization. On the basis of these two theoretical perspectives, we examine how employees’ diminished self-esteem from abusive supervision can motivate destructive work behavior (i.e., supervisor-directed deviance, organizational deviance) and self-presentational behavior (i.e., putting on a façade, ingratiation). Additionally, employees’ turnover intentions, which are an indicator of employees’ psychological detachment from the organization, are considered a moderator of the effects of abusive supervision on diminished self-esteem and associated behavior such that high turnover intentions attenuate the effects. Results of two field studies and a daily diary study support the hypothesized model and show that abusive supervision indirectly influences employees’ workplace deviance and self-presentational behavior via diminished self-esteem. As predicted, the effects are stronger for employees with lower versus higher turnover intentions.
Evaluation of Vitamin D Status in Rheumatoid Arthritis and Its Association with Disease Activity across 15 Countries: “The COMORA Study”

The aims of this study are to evaluate vitamin D status in 1413 RA patients of COMORA study from 15 countries and to analyze relationship between patients' RA characteristics and low levels of vitamin D. All demographic, clinical, and biological data and RA comorbidities were completed. The results showed that the average of vitamin D serum dosage was 27.3 ng/mL ± 15.1 [0.1–151]. Status of vitamin D was insufficient in 54.6% and deficient in 8.5% of patients. 43% of RA patients were supplemented with vitamin D and absence of supplementation on vitamin D was related to higher prevalence of vitamin D deficiency (p < 0.001). Finally, our study shows that the status of low levels of vitamin D is common in RA in different countries and under different latitudes. Absence of supplementation on vitamin D was related to higher prevalence of vitamin D deficiency. Low levels of vitamin D were associated with patients characteristics (age, BMI, and educational level), RA (disease activity and corticosteroid dosage), and comorbidities (lung disease and osteoporosis therapy). This suggests the need for a particular therapeutic strategy to improve vitamin D status in RA patients.
Optimal stopping for energy efficiency with delay constraints in Cognitive Radio networks

In this paper the problem of delay tolerant message data transmission scheduling over Cognitive Radio (CR) enabled wireless networks is considered with special emphasis on high mobility users (vehicles). The proliferation of delay tolerant applications (social networking updates, emails, updates over the air to mention just a few) can drive efficient utilization of available spectrum by Secondary Users (SU) under a CR enabled cellular network. Under the inherent stochasticity of available of transmission opportunities, the challenge is to select an optimized time duration to launch the data transmission in order to minimize the overall energy cost while satisfying the information delay constraint (with focus on delay-tolerant messages). To this end, a novel relaying scheme to deal with the problem of energy-delay trade-off, based on optimal stopping programming (OSP), is presented, whilst exploring different candidate solutions for message transmission. Additionally, we also factor energy consumption of DRAM that is used to store the message at the terminal and show its pivotal role on the different store carry and forward data transmission schemes.
Recall of Categorized Lists as a Function of Organization, Associative Frequency, Cues at Recall, and Inter-Trial Variability of Order

10 subjects were randomly assigned to each cell of a 2 × 2 × 2 × 2 factorial design. Lists of 10 categories with 8 items per category were learned and recalled. Significant effects in total word recall were observed for (a) associative frequency of category instances, (b) blocked vs random organization of category instances during acquisition, (c) category label cues vs no cues at recall, and (d) the interaction of associative frequency and cues at recall. Category label cues did not facilitate recall of low-frequency items but did facilitate recall of high-frequency items. High associative frequency and blocked organization of category instances both significantly increased words per category recalled. High associative frequency and category label cues at recall both significantly increased the number of categories recalled.
Product creativity: conceptual model, measurement and characteristics

This study investigates the composition of product creativity by examining elements of consumer products from the consumer's perspective. This study presents a conceptual model of product creativity assessment within the context of the information processing model. A product creativity survey of 52 items, based on the Creative Product Analysis Matrix and the literature findings, was completed by 205 university students. Results of an exploratory and confirmatory factor analysis indicated six main product creativity dimensions and the percentages of the total variance accounted for by each dimension, which are: resolution (27%); emotion (9%); centrality (8%); importance (8%); desire (7%); and novelty (6%). Results of a stepwise regression indicated that these three product creativity dimensions (centrality, importance and desire) significantly predict customer satisfaction (40% of the explained variance) and purchasability (33% of the explained variance) of creative products. The study concludes with related implications to enhancing product creativity.
Principal selection panels: strategies, preferences and perceptions

Purpose – The purpose of this article is to report a study of the strategies members of principal selection panels use to select the best candidate for a principal position.Design/methodology/approach – The study draws on both qualitative and quantitative data. The quantitative analysis drawn on data collected from school supervisors and school principals confirmed a four‐factor structure and qualitative interview data was used to supplement findings.Findings – In order of importance the strategies employed by selection panels were: panel professionalism, the interview, making the cut and pre‐interview.Practical implications – Findings indicate that the selection component of principal recruitment remains at best an uncertain science. Tensions endure between beliefs and perceptions of panel members from different backgrounds. These include beliefs about competence and level of involvement in important activities such as short‐listing. Relational ties, religious affiliation and values congruence are import.
Ankle Performance after Ankle Fracture: A Randomized Study of Early Mobilization

In a prospective, randomized study, 30 patients were evaluated after ankle fracture treated by means of open reduction and internal fixation. The patients were randomized to either postoperative immobilization in a plaster cast for 6 weeks or early mobilization (1–2 weeks after surgery) in an ankle brace. Both regimens allowed weightbearing. Evaluation after 10 weeks and after 12 months included clinical assessment and isokinetic muscle strength measurements. Patients with impaired ankle function, as shown by means of an ankle score at 12 months, were followed for 3 years. At 10 weeks, impaired muscle torque and restricted range of motion was found on the affected side. This impairment was significantly less in the brace group. At 12 months, range of motion of the ankle and subtalar joints was restored, but dorsiflexion was still better in the brace group. Score values from a functional score did not correlate with muscle strength.
Making the International Local: The Terrorist Attack on the USS Cole, Local Casualties, and Media Coverage

I explore whether newspapers that represent regions experiencing "local casualties," that is, fatalities from an international violent event, give greater coverage to the incident. Research suggests that local casualties influence domestic politics, yet scholars have given little attention to either the influence of local casualties on reporting or the impact of international events on local press coverage. I examine the effect of local casualties on local media by analyzing the frequency of newspaper coverage of the October 2000 terrorist bombing of the USS Cole. Using a variety of techniques, including random effects logit and repeat failure hazard analysis, I find that newspapers from areas that experienced casualties from the Cole attack were more likely to report on the bombing, even when controlling for paper-specific and temporal effects. Driven by community casualties, variation in local media attention to an international news story may help to explain why the effects of international events on individual attitudes and domestic political effects vary geographically, a necessary condition for institutional arguments for the democratic peace.
Two Drosophila Ada2 Homologues Function in Different Multiprotein Complexes

ABSTRACT The reversible acetylation of the N-terminal tails of histones is crucial for transcription, DNA repair, and replication. The enzymatic reaction is catalyzed by large multiprotein complexes, of which the best characterized are the Gcn5-containing N-acetyltransferase (GNAT) complexes. GNAT complexes from yeast to humans share several conserved subunits, such as Ada2, Ada3, Spt3, and Tra1/TRRAP. We have characterized these factors in Drosophila and found that the flies have two distinct Ada2 variants (dAda2a and dAda2b). Using a combination of biochemical and cell biological approaches we demonstrate that only one of the two Drosophila Ada2 homologues, dAda2b, is a component of Spt-Ada-Gcn5-acetyltransferase (SAGA) complexes. The other Ada2 variant, dAda2a, can associate with dGcn5 but is not incorporated into dSAGA-type complexes. This is the first example of a complex-specific association of the Ada-type transcriptional adapter proteins with GNATs. In addition, dAda2a is part of Gcn5-independent complexes, which are concentrated at transcriptionally active regions on polytene chromosomes. This implicates novel functions for dAda2a in transcription. Humans and mice also possess two Ada2 variants with high homology to dAda2a and dAda2b, respectively. This suggests that the mammalian and fly homologues of the transcriptional adapter Ada2 form two functionally distinct subgroups with unique characteristics.
Brain Activation during Human Male Ejaculation

Brain mechanisms that control human sexual behavior in general, and ejaculation in particular, are poorly understood. We used positron emission tomography to measure increases in regional cerebral blood flow (rCBF) during ejaculation compared with sexual stimulation in heterosexual male volunteers. Manual penile stimulation was performed by the volunteer's female partner. Primary activation was found in the mesodiencephalic transition zone, including the ventral tegmental area, which is involved in a wide variety of rewarding behaviors. Parallels are drawn between ejaculation and heroin rush. Other activated mesodiencephalic structures are the midbrain lateral central tegmental field, zona incerta, subparafascicular nucleus, and the ventroposterior, midline, and intralaminar thalamic nuclei. Increased activation was also present in the lateral putamen and adjoining parts of the claustrum. Neocortical activity was only found in Brodmann areas 7/40, 18, 21, 23, and 47, exclusively on the right side. On the basis of studies in rodents, the medial preoptic area, bed nucleus of the stria terminalis, and amygdala are thought to be involved in ejaculation, but increased rCBF was not found in any of these regions. Conversely, in the amygdala and adjacent entorhinal cortex, a decrease in activation was observed. Remarkably strong rCBF increases were observed in the cerebellum. These findings corroborate the recent notion that the cerebellum plays an important role in emotional processing. The present study for the first time provides insight into which regions in the human brain play a primary role in ejaculation, and the results might have important implications for our understanding of how human ejaculation is brought about, and for our ability to improve sexual function and satisfaction in men.
The anti-inflammatory effects of venlafaxine in the rat model of carrageenan-induced paw edema

Objective(s): Recently anti-inflammatory effects of antidepressants have been demonstrated. Venlafaxine belongs to newer antidepressants with serotonin norepinephrine reuptake inhibition property. The pain alleviating properties of venlafaxine in different pain models such as neurogenic pain, diabetic neuropathy, and fibromyalgia have been demonstrated. Anti-inflammatory effects of venlafaxine and also its underlying mechanisms remain unclear. The present study was designed to evaluate the anti-inflammatory effects of venlafaxine and determine possible underlying mechanisms. Materials and Methods: We examined the anti-inflammatory effects of intraperitoneal (IP) and intracerebroventricular (ICV) administration of venlafaxine in the rat model of carrageenan-induced paw edema. Results: Our results showed that both IP (50 and 100 mg/kg) and ICV (50 and 100 μg/rat) injection of venlafaxine inhibited carrageenan-induced paw edema. Also IP and ICV administration of venlafaxine significantly decreased myeloperoxidase (MPO) activity and interleukin (IL)-1β and tumor necrosis factor (TNF)-α production. Finally, we tried to reverse the anti-inflammatory effect of venlafaxine by yohimbine (5 mg/kg, IP), an alpha2-adrenergic antagonist. Our results showed that applied antagonist failed to change the anti-inflammatory effect of venlafaxine. Conclusion: These results demonstrated that venlafaxine has potent anti-inflammatory effect which is related to the peripheral and central effects of this drug. Also we have shown that anti-inflammatory effect of venlafaxine is mediated mostly through the inhibition of IL-1β and TNF-α production and decreases MPO activity in the site of inflammation.
Interaction with the Epstein-Barr Virus Helicase Targets Zta to DNA Replication Compartments

ABSTRACT Zta has a dual role in the Epstein-Barr virus (EBV) lytic cycle, acting as a key regulator of EBV lytic gene expression and also being essential for lytic viral DNA replication. Zta's replication function is mediated in part through interactions with the core viral replication proteins. We now show interaction between Zta and the helicase (BBLF4) and map the binding region to within amino acids (aa) 22 to 86 of the Zta activation domain. In immunofluorescence assays, green fluorescent protein (GFP)-tagged BBLF4 localized to the cytoplasm of transfected cells. Cotransfection of Zta resulted in translocation of BBLF4-GFP into the nucleus indicating interaction between these two proteins. However, Zta with a deletion of aa 24 to 86 was unable to mediate nuclear translocation of BBLF4-GFP. Results obtained with Zta variants carrying deletions across the aa 24 to 86 region indicated more than one contact site for BBLF4 within this domain, and this was reinforced by the behavior of the four-point mutant Zta (m22/26,74/75), which was severely impaired for BBLF4 interaction. Binding of BBLF4 to Zta was confirmed using GST affinity assays. In both cotransfection-replication assays and replication assays performed in EBV-positive P3HR1 cells, the Zta (m22/26,74/75) mutant was replication defective. In Zta-transfected D98-HR1 cells, replication compartments could be detected by immunofluorescence staining using anti-BMRF1 monoclonal antibody. Cells transfected with Zta variants that were defective for helicase binding still formed replication compartments, but Zta was excluded from these compartments. These experiments reveal a role for the Zta-helicase interaction in targeting Zta to sites of viral DNA replication.
A Deeper Investigation Into the Psychological Changes of Intellectually Gifted Students Attending a Residential Academy

This discourse is the qualitative component of a mixed-methods study that examined how students were psychologically affected while attending a 2-year residential high school (Academy) in the Midwest. This aspect of the study focused on the emic perspective of nine students using a phenomenological-type approach. To that end, interviews were conducted with nine senior students with a wide range of Youth Outcome Questionnaire-Self Report 2.0 assessed during their junior year from the quantitative portion. From the interviews, 28 invariant constituents emerged. Four categories were generated from the invariant constituents to describe student experiences: psychological changes, academic adjustment, social adjustment, and social comparison. Students made cognitive and behavioral changes to adapt to the different challenges of the school. Though generally stressful, the students described their enrollment at the school as beneficial and felt more prepared for college.