Miracle-dz/UniFAR-FTUs huggingface dataset:
Inter-Comparison and Evaluation of Remote Sensing Precipitation Products over China from 2005 to 2013

Precipitation is a key aspect of the climate system. In this paper, the dependability of five satellite precipitation products (TRMM [Tropical Rainfall Measuring Mission] 3BV42, PERSIANN [Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks] CDR, GSMaP [Global Satellite Mapping of Precipitation] RENALYSIS, CMORPH [Climate Prediction Center’s morphing technique] BLD and CMORPH_RAW) were compared with in situ measurements over China for the period of 2005 to 2013. To completely evaluate these precipitation products, the annual, seasonal and monthly precipitation averages were calculated. Overall, the Huaihe River and Qinlin mountains are shown to have heavy precipitation to the southeast and lighter precipitation to the northwest. The comparison results indicate that Gauge correction (CMORPH_BLD) improves the quality of the original satellite products (CMORPH_RAW), resulting in the higher correlation coefficient (CC), the low relative bias (BIAS) and root mean square error (RMSE). Over China, the GSMaP_RENALYSIS outperforms other products and shows the highest CC (0.91) and lowest RMSE (0.85 mm/day) and all products except for PERSIANN_CDR exhibit underestimation. GSMaP_RENALYSIS gives the highest of probability of detection (81%), critical success index (63%) and lowest false alarm ratio (36%) while TRMM3BV42 gives the highest of frequency bias index (1.00). Over Tibetan Plateau, CMORPH_RAW demonstrates the poorest performance with the biggest BIAS (4.2 mm/month) and lowest CC (0.22) in December 2013. GSMaP_RENALYSIS displays quite consistent with in situ measurements in summer. However, GSMaP_RENALYSIS and CMORPH_RAW underestimate precipitation over South China. CMORPH_BLD and TRMM3BV42 show consistent with high CC (>0.8) but relatively large RMSE in summer.
Laser and Microwave Generations in Nitrogen

This paper describes the results obtained in the three sets of experiments. The laser emission and microwaves have been obtained almost with the same experimental setup. The ultraviolet radiation coming from the current carrying the spark channel pumps the N<sub>2</sub> molecules to the upper-excited <inline-formula> <tex-math notation="LaTeX">$C^{3}\pi _{u}$ </tex-math></inline-formula> level to yield the nitrogen laser pulses at 337.1 nm of long (>220 ns) duration in the experimental setup used. The electromagnetic waves observed at the single microwave frequency close to 1 GHz and at 337.1 nm (=prominent nitrogen laser line) are the coherent radiations due to the maser action and the laser action, respectively. An attempt is made to relate one of these concepts to the lightning phenomena.
Mapping Proprioception across a 2D Horizontal Workspace

Relatively few studies have been reported that document how proprioception varies across the workspace of the human arm. Here we examined proprioceptive function across a horizontal planar workspace, using a new method that avoids active movement and interactions with other sensory modalities. We systematically mapped both proprioceptive acuity (sensitivity to hand position change) and bias (perceived location of the hand), across a horizontal-plane 2D workspace. Proprioception of both the left and right arms was tested at nine workspace locations and in 2 orthogonal directions (left-right and forwards-backwards). Subjects made repeated judgments about the position of their hand with respect to a remembered proprioceptive reference position, while grasping the handle of a robotic linkage that passively moved their hand to each judgement location. To rule out the possibility that the memory component of the proprioceptive testing procedure may have influenced our results, we repeated the procedure in a second experiment using a persistent visual reference position. Both methods resulted in qualitatively similar findings. Proprioception is not uniform across the workspace. Acuity was greater for limb configurations in which the hand was closer to the body, and was greater in a forward-backward direction than in a left-right direction. A robust difference in proprioceptive bias was observed across both experiments. At all workspace locations, the left hand was perceived to be to the left of its actual position, and the right hand was perceived to be to the right of its actual position. Finally, bias was smaller for hand positions closer to the body. The results of this study provide a systematic map of proprioceptive acuity and bias across the workspace of the limb that may be used to augment computational models of sensory-motor control, and to inform clinical assessment of sensory function in patients with sensory-motor deficits.
Genetic Analysis of Central Carbon Metabolism Unveils an Amino Acid Substitution That Alters Maize NAD-Dependent Isocitrate Dehydrogenase Activity

Background Central carbon metabolism (CCM) is a fundamental component of life. The participating genes and enzymes are thought to be structurally and functionally conserved across and within species. Association mapping utilizes a rich history of mutation and recombination to achieve high resolution mapping. Therefore, applying association mapping in maize (Zea mays ssp. mays), the most diverse model crop species, to study the genetics of CCM is a particularly attractive system. Methodology/Principal Findings We used a maize diversity panel to test the CCM functional conservation. We found heritable variation in enzyme activity for every enzyme tested. One of these enzymes was the NAD-dependent isocitrate dehydrogenase (IDH, E.C. 1.1.1.41), in which we identified a novel amino-acid substitution in a phylogenetically conserved site. Using candidate gene association mapping, we identified that this non-synonymous polymorphism was associated with IDH activity variation. The proposed mechanism for the IDH activity variation includes additional components regulating protein level. With the comparison of sequences from maize and teosinte (Zea mays ssp. Parviglumis), the maize wild ancestor, we found that some CCM genes had also been targeted for selection during maize domestication. Conclusions/Significance Our results demonstrate the efficacy of association mapping for dissecting natural variation in primary metabolic pathways. The considerable genetic diversity observed in maize CCM genes underlies heritable phenotypic variation in enzyme activities and can be useful to identify putative functional sites.
Moral dimensions of human–wildlife conflict

Despite increasing support for conservation globally, controversy over specific conservation policies persists among diverse stakeholders. Investigating the links between morals in relation to conservation can help increase understanding about why humans support or oppose policy, especially related to human–wildlife conflict or human conflict over wildlife. Yet the moral dimension of human–wildlife conflict has mostly gone unconsidered and unmeasured; thus, policy and programmatic efforts to reduce controversy may be missing a key part of the equation. We conducted a web‐based survey (n = 1239 respondents) in Michigan (U.S.A.) to investigate cognitive and emotional influences on the value–behavior relationship. Respondents were identified by their interest and involvement in Michigan wolf management. The survey consisted of questions about values, emotions, cognitions, and behaviors relative to wolves in Michigan. We used path analysis to explore whether emotions and cognitions mediated the relationship between value and behavior. Most respondents attributed intrinsic value to wolves (n = 734) and all life (n = 773) and engaged in behaviors that benefited wolf populations and ecosystems regardless of stakeholder group (e.g., environmentalist, farmer). Attributing intrinsic value to wolves was positively related to favorable emotions toward wolves and cognitive assessments that hunting and trapping of wolves is unacceptable. Despite similarities in attribution of intrinsic value, groups differed in emotions and cognitions about wolf hunting. These differences provide a useful way to predict stakeholder behavior. Our findings may inform interventions aimed at increasing support for wolf management policies and positive interactions among stakeholders and wildlife. Leveraging agreement over intrinsic value may foster cooperation among stakeholders and garner support for controversial conservation policy.
Comparison of Automated Titanium Fasteners to Hand-Tied Knots in Open Aortic Valve Replacement

Objective Aortic cross-clamp and cardiopulmonary bypass times are independent predictors of postoperative morbidity and mortality. Reducing ischemic times with automated titanium fasteners may improve surgical outcomes. This study compared operative times and costs of titanium fasteners versus hand-tied knots for prosthesis securement in open aortic valve replacement. Methods A randomized control trial was conducted during a 16-month period at a single university medical center. Patients undergoing elective aortic valve replacement were randomized to the titanium fastener (n = 37) or hand-tied groups (n = 36). Knotting, aortic cross-clamp, cardiopulmonary bypass, and total operating room times were recorded. Hospital charges were also calculated for these procedures. Results Baseline characteristics, concomitant procedures, prosthetic valve size, and sutures were similar between groups. The titanium fastener group had significantly reduced knotting (7.4 vs. 13.0 minutes, P < 0.001), aortic cross-clamp (69 vs. 90 minutes, P < 0.05), cardiopulmonary bypass (86 vs. 114 minutes, P < 0.05), and total operating room times (234 vs. 266 minutes, P < 0.05). Intraoperative complications occurred more frequently in the hand-tied group compared with the titanium fastener group. Postoperative complications were similar between groups. Operating room costs were significantly higher in the titanium fastener group (US $10,428 vs. US $9671, P = 0.01). Hospitalization costs did not differ significantly between the titanium fastener and hand-tied group (US $23,987 vs. US $21,068, P = 0.12). Conclusions Titanium fastener use was associated with shorter knotting, aortic cross-clamp, cardiopulmonary bypass, and operating room times and fewer intraoperative complications in open aortic valve replacement, without significantly increasing hospitalization cost.
Societies Drifting Apart? Behavioural, Genetic and Chemical Differentiation between Supercolonies in the Yellow Crazy Ant Anoplolepis gracilipes

Background In populations of most social insects, gene flow is maintained through mating between reproductive individuals from different colonies in periodic nuptial flights followed by dispersal of the fertilized foundresses. Some ant species, however, form large polygynous supercolonies, in which mating takes place within the maternal nest (intranidal mating) and fertilized queens disperse within or along the boundary of the supercolony, leading to supercolony growth (colony budding). As a consequence, gene flow is largely confined within supercolonies. Over time, such supercolonies may diverge genetically and, thus, also in recognition cues (cuticular hydrocarbons, CHC's) by a combination of genetic drift and accumulation of colony-specific, neutral mutations. Methodology/Principal Findings We tested this hypothesis for six supercolonies of the invasive ant Anoplolepis gracilipes in north-east Borneo. Within supercolonies, workers from different nests tolerated each other, were closely related and showed highly similar CHC profiles. Between supercolonies, aggression ranged from tolerance to mortal encounters and was negatively correlated with relatedness and CHC profile similarity. Supercolonies were genetically and chemically distinct, with mutually aggressive supercolony pairs sharing only 33.1%±17.5% (mean ± SD) of their alleles across six microsatellite loci and 73.8%±11.6% of the compounds in their CHC profile. Moreover, the proportion of alleles that differed between supercolony pairs was positively correlated to the proportion of qualitatively different CHC compounds. These qualitatively differing CHC compounds were found across various substance classes including alkanes, alkenes and mono-, di- and trimethyl-branched alkanes. Conclusions We conclude that positive feedback between genetic, chemical and behavioural traits may further enhance supercolony differentiation through genetic drift and neutral evolution, and may drive colonies towards different evolutionary pathways, possibly including speciation.
Are Older Adults Perceived as A Threat to Society? Exploring Perceived Age-Based Threats in 29 Nations.

Objectives The present study adds to the current body of literature by simultaneously examining the public perception of young and old people as posing realistic threats (e.g., to the group's power, resources, and welfare) and symbolic threats (e.g., to one's world view, belief system and values). Methods The fourth wave of the European Social Survey was administered to individuals from 29 countries. Analysis is based on 56,170 individuals, who had data on the four relevant indicators. The study relied on a latent profile analysis to develop a typology of perceived realistic and symbolic threats to society by younger and older adults. Results A three-profile solution indicated that the perception of older and younger adults as threats to society often co-occurs. Sociodemographic characteristics at the individual-level and the Gini coefficient (e.g., an inequality indicator) at the country-level had differential associations with the profiles identified. Conclusions The study calls for a more balanced approach which evaluates attitudes toward both younger and older adults as potential sources of threat. Attention should be paid to individual- and national-level characteristics associated with age-based threats (e.g., the perception of a group, defined by its chronological age, as threatening).
On-machine fabrication of high-aspect-ratio micro-electrodes and application in vibration-assisted micro-electrodischarge drilling of tungsten carbide

Abstract The concept of fabricating on-machine high-aspect-ratio micro-electrodes arises from the need to fabricate small and deep micro-holes in micro-electrical discharge machining (micro-EDM). In the present study, investigations are conducted on the fabrication of high-aspect-ratio micro-electrodes using two simple and cost-effective micro-EDM-based processes: the ‘turning-μEDM’ hybrid process and the ‘moving-electrode-block-μEDM’ process. Process descriptions and important aspects for successful fabrication of high-aspect-ratio micro-electrodes are discussed. In addition, the application of these micro-electrodes in the fabrication of deep micro-holes in tungsten carbide using normal micro-EDM and vibration-assisted micro-EDM is presented. It is found that the turning-μEDM process can generate finer micro-electrodes for easily machinable materials such as brass, but its application to the machining of deep micro-holes in tungsten Carbide is limited by the extreme tool wear of the brass electrode. The block-μEDM process can generate microelectrodes with hard, difficult-to-cut, and high-melting-point materials such as copper tungsten (alloy) and tungsten with much higher aspect ratios. However, the taper angle of the fabricated micro-electrodes is a common problem in the stationary block-μEDM process. This problem is reduced to a great extent by using block-μEDM with a moving electrode. Micro-holes with an aspect ratio of 16.7 are achieved using vibration-assisted micro-EDM with the fabricated tungsten micro-electrode machined by the moving-electrode-block-μEDM process.
The power of positive and negative expectations to influence reported symptoms and mood during exposure to wind farm sound.

OBJECTIVE Wind farm developments have been hampered by claims that sound from wind turbines causes symptoms and negative health reports in nearby residents. As scientific reviews have failed to identify a plausible link between wind turbine sound and health effects, psychological expectations have been proposed as an explanation for health complaints. Building on recent work showing negative expectations can create symptoms from wind turbines, we investigated whether positive expectations can produce the opposite effect, in terms of a reduction in symptoms and improvements in reported health. METHOD 60 participants were randomized to either positive or negative expectation groups and subsequently exposed to audible wind farm sound and infrasound. Prior to exposure, negative expectation participants watched a DVD incorporating TV footage about health effects said to be caused by infrasound produced by wind turbines. In contrast, positive expectation participants viewed a DVD that outlined the possible therapeutic effects of infrasound exposure. RESULTS During exposure to audible windfarm sound and infrasound, symptoms and mood were strongly influenced by the type of expectations. Negative expectation participants experienced a significant increase in symptoms and a significant deterioration in mood, while positive expectation participants reported a significant decrease in symptoms and a significant improvement in mood. CONCLUSION The study demonstrates that expectations can influence symptom and mood reports in both positive and negative directions. The results suggest that if expectations about infrasound are framed in more neutral or benign ways, then it is likely reports of symptoms or negative effects could be nullified.
Treatment of femoral and tibial fractures in puppies by elastic plate osteosynthesis

Summary Seventeen puppies, two to four months old, with a femoral (n=12) or tibial (n=5) diaphyseal fracture were treated by elastic plate osteosynthesis with a Veterinary Cuttable Plate (VCP) or straight plate. In one case of femoral fracture treated with a VCP, plate bending due to an excessive elasticity of the implant was observed three days after the osteosynthesis and surgical revision was required. Two cases of femoral overgrowth and one case of slight femoral head and neck retroversion were identified during the radiographic follow-up but without any clinical consequences. Bone healing was obtained for all fractures four to eight weeks (5.64±0.88 weeks) after the surgical procedure, and functional results were excellent in all cases. Our study confirms that elastic plate osteosynthesis with either a VCP or straight plate can be used to treat femoral diaphyseal fractures in medium and large breed puppies less than four months old, but that modification of implant elasticity or rigid osteosynthesis use is required when such puppies reach four months. The same technique can also be used successfully to treat tibial fractures in puppies younger than four months old.
Perfect-absorption graphene metamaterials for surface-enhanced molecular fingerprint spectroscopy

Graphene plasmon with extremely strong light confinement and tunable resonance frequency represents a promising surface-enhanced infrared absorption (SEIRA) sensing platform. However, plasmonic absorption is relatively weak (approximately 1%–9%) in monolayer graphene nanostructures, which would limit its sensitivity. Here, we theoretically propose a hybrid plasmon-metamaterial structure that can realize perfect absorption in graphene with a low carrier mobility of 1000 cm2 V−1 s−1. This structure combines a gold reflector and a gold grating to the graphene plasmon structures, which introduce interference effect and the lightning-rod effect, respectively, and largely enhance the coupling of light to graphene. The vibration signal of trace molecules can be enhanced up to 2000-fold at the hotspot of the perfect-absorption structure, enabling the SEIRA sensing to reach the molecular level. This hybrid metal-graphene structure provides a novel path to generate high sensitivity in nanoscale molecular recognition for numerous applications.
Performance of the Achutha Menon Centre Diabetes Risk Score in Identifying Prevalent Diabetes in Tamil Nadu, India

Background The Achutha Menon Centre Diabetes Risk Score (AMCDRS), which was developed in rural Kerala State, South India, had not previously been externally validated. We examined the performance of the AMCDRS in urban and rural areas in the district of Vellore in the South Indian state of Tamil Nadu, and compared it with other diabetes risk scores developed from India. Methods We used the data from 4,896 participants (30 to 64 years) of a cross-sectional study conducted in Vellore (2010 to 2012), to calculate the AMCDRS scores using age, family history, and waist circumference. Sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV), and the area under the receiver operating characteristic curve (AROC) were calculated for undiagnosed and total diabetes. Results Of the 4,896 individuals surveyed, 274 (5.6%) had undiagnosed diabetes and 759 (15.5%) had total diabetes. The AMCDRS, with an optimum cut-point of ≥4, identified 45.0% for further testing with 59.5% sensitivity, 60.5% specificity, 9.1% PPV, 95.8% NPV, and an AROC of 0.639 (95% confidence interval [CI], 0.608 to 0.670) for undiagnosed diabetes. The corresponding figures for total diabetes were 75.1%, 60.5%, 25.9%, 93.0%, and 0.731 (95% CI, 0.713 to 0.750), respectively. The AROC for the AMCDRS was not significantly different from that of the Indian Diabetes Risk Score, the Ramachandran or the Chaturvedi risk scores for total diabetes, but was significantly lower than the AROC of the Chaturvedi score for undiagnosed diabetes. Conclusion The AMCDRS is a simple diabetes risk score that can be used to screen for undiagnosed and total diabetes in low-resource primary care settings in India. However, it probably requires recalibration to improve its performance for undiagnosed diabetes.
Inference of cellular level signaling networks using single‐cell gene expression data in Caenorhabditis elegans reveals mechanisms of cell fate specification

Motivation: Cell fate specification plays a key role to generate distinct cell types during metazoan development. However, most of the underlying signaling networks at cellular level are not well understood. Availability of time lapse single‐cell gene expression data collected throughout Caenorhabditis elegans embryogenesis provides an excellent opportunity for investigating signaling networks underlying cell fate specification at systems, cellular and molecular levels. Results: We propose a framework to infer signaling networks at cellular level by exploring the single‐cell gene expression data. Through analyzing the expression data of nhr‐25, a hypodermis‐specific transcription factor, in every cells of both wild‐type and mutant C.elegans embryos through RNAi against 55 genes, we have inferred a total of 23 genes that regulate (activate or inhibit) nhr‐25 expression in cell‐specific fashion. We also infer the signaling pathways consisting of each of these genes and nhr‐25 based on a probabilistic graphical model for the selected five founder cells, ‘ABarp’, ‘ABpla’, ‘ABpra’, ‘Caa’ and ‘Cpa’, which express nhr‐25 and mostly develop into hypodermis. By integrating the inferred pathways, we reconstruct five signaling networks with one each for the five founder cells. Using RNAi gene knockdown as a validation method, the inferred networks are able to predict the effects of the knockdown genes. These signaling networks in the five founder cells are likely to ensure faithful hypodermis cell fate specification in C.elegans at cellular level. Availability and Implementation: All source codes and data are available at the github repository https://github.com/xthuang226/Worm_Single_Cell_Data_and_Codes. git. Contact: zhuyuan@cug.edu. cn Supplementary information: Supplementary data are available at Bioinformatics online.