Miracle-dz/UniFAR-FTUs huggingface dataset:
Mixed Emotions: Network Analyses of Intra-Individual Co-Occurrences Within and Across Situations

This study revisits the structure of emotions by using a co-occurrence network analysis. While previous studies have examined the structure of emotions primarily through interindividual correlations, we investigated how often and which specific positive and negative emotions occur together within individuals. Two studies were conducted with high school students, one (N = 21,678) using retrospective emotion measures (open-ended questions and 28 rated items) and the other (N = 472) using in-the-moment emotion measures (experience sampling). As in previous studies, positive and negative emotion ratings were negatively correlated across individuals, and this negative correlation became stronger when measurement error was controlled. Nevertheless, network analyses of both the open-ended responses and of emotion rating scales found frequent co-occurrences between both positive and negative emotions within individuals and within situations. Across all networks, happy, tired, and stressed were among the most frequent emotions that occurred together with emotions of opposite valence. The network analyses presented in this article open new directions to the long-lasting debate about the structure of emotions by revealing co-occurrences that interindividual correlations would not show.
pH regulates the polymerization of actin in the sea urchin egg cortex

The state of actin in the isolated cortex of the unfertilized sea urchin egg can be controlled by experimentally manipulating the pH of the isolation medium. Cortices isolated at the pH of the unfertilized egg (6.5--6.7) do not contain filamentous actin, while those isolated at the pH of the fertilized egg (7.3--7.5) develop large numbers of microvilli which contain bundles of actin filaments. Cortices that are isolated at pH 6.5 and then transferred to isolation medium buffered at pH 7.5 also develop actin filaments. However, the filaments are not arranged in bundles and microvilli do not form. Although the cortical granules in cortices isolated at pH 6.5 discharge at a free Ca++ concentration of approximately 10 micrometer, actin polymerization is not induced by increasing the Ca++ concentration of the isolation medium. These results suggest that the increase in cytoplasmic pH which occurs following fertilization induces the polymerization of actin in the egg cortex.
Residual Stress Study in Oxide Scale Obtained on High Temperature Oxidation of AISI 430 Stainless Steel

The objective of this work was to investigate high temperature oxidation behavior of AISI 430 stainless steel, which was proposed to use as interconnector in the planar solid oxide fuel cells (SOFCs). The oxidation of the alloy has been conducted at 700°C, 800°C and 900°C for 12h-96h by thermal gravimetric analysis (TGA) system. The oxide surface morphology, cross-section microstructure and the chemical composition of the oxide scales were performed by FEG-SEM and EDX. The X-ray diffraction (XRD) was used to identify the oxide phases formed on the alloy and to determine the residual stress in the scale. It has been found that the oxide scale composed of a inner Cr2O3 layer and an outer Mn1.5Cr1. 5O4 layer. The residual stresses in both oxide layers are compressive and the residual stress evolutions in the two layers are different according the oxidation temperature.
ASSOCIATION OF GLYCATED HAEMOGLOBIN WITH CARDIOVASCULAR DISEASE AND METABOLIC SYNDROME IN ASIAN INDIANS WITH NORMAL GLUCOSE TOLERANCE

Objective: This study examines the association of glycated hemoglobin (HbA1c) with cardiovascular disease risk factors, coronary artery disease (CAD) and metabolic syndrome in Asian Indians with normal glucose tolerance [NGT]. Research design and methods: This cross-sectional study recruited subjects from phase 3 of the Chennai Urban Rural Epidemiology Study [CURES] an epidemiological study in a representative population of Chennai [formerly Madras], in South India conducted between January 2003 and June 2004 . Included were 1644 subjects with normal glucose tolerance, ie, fasting plasma glucose <100 mg/dl [5.6 mmol/L] and 2 hour post load plasma glucose <140 mg/dl [7.8 mmol/L]. HbA1c was measured using the Biorad Variant machine. Metabolic syndrome was defined based on modified Adult Treatment Panel III (ATP III) guidelines. Results: The mean (SD) HbA1c value in the study cohort was 5.5%(0.4). HbA1c showed a significant association with body mass index [ β =1.640, p<0.001],systolic [ β =1.961,p=0.028] diastolic [ β pressure,waist p<0.001], LDL cholesterol [ β =0.262,p<0.001], fasting insulin [ β =1.500,p<0.001] and homeostasis model assessment (HOMA) insulin resistance [ β =0.369,p<0.001] after adjusting for age and gender. Regression analysis showed that HbA1c had a strong association with metabolic syndrome, which persisted after adjusting for age and gender [Odds Ratio (OR):2.9, 95% confidence interval (CI):2.08–4.00,p<0001]. HbA1c also had a strong association with coronary artery disease [OR:2.6,
Developmental RNA processing of 3′UTRs in Hox mRNAs as a context-dependent mechanism modulating visibility to microRNAs

The Drosophila Hox gene Ultrabithorax (Ubx) controls the development of thoracic and abdominal segments, allocating segment-specific features to different cell lineages. Recent studies have shown that Ubx expression is post-transcriptionally regulated by two microRNAs (miRNAs), miR-iab4 and miR-iab8, acting on target sites located in the 3′ untranslated regions (UTRs) of Ubx mRNAs. Here, we show that during embryonic development Ubx produces mRNAs with variable 3′UTRs in different regions of the embryo. Analysis of the resulting remodelled 3′UTRs shows that each species harbours different sets of miRNA target sites, converting each class of Ubx mRNA into a considerably different substrate for miRNA regulation. Furthermore, we show that the distinct developmental distributions of Ubx 3′UTRs are established by a mechanism that is independent of miRNA regulation and therefore are not the consequence of miR-iab4/8-mediated RNA degradation acting on those sensitive mRNA species; instead, we propose that this is a hard-wired 3′UTR processing system that is able to regulate target mRNA visibility to miRNAs according to developmental context. We show that reporter constructs that include Ubx short and long 3′UTR sequences display differential expression within the embryonic central nervous system, and also demonstrate that mRNAs of three other Hox genes suffer similar and synchronous developmental 3′UTR processing events during embryogenesis. Our work thus reveals that developmental RNA processing of 3′UTR sequences is a general molecular strategy used by a key family of developmental regulators so that their transcripts can display different levels of visibility to miRNA regulation according to developmental cues.
Exponential time algorithms for the minimum dominating set problem on some graph classes

The minimum dominating set problem remains NP-hard when restricted to any of the following graph classes: <i>c</i>-dense graphs, chordal graphs, 4-chordal graphs, weakly chordal graphs, and circle graphs. Developing and using a general approach, for each of these graph classes we present an exponential time algorithm solving the minimum dominating set problem faster than the best known algorithm for general graphs. Our algorithms have the following running time: <i>O</i>(1.4124<sup><i>n</i></sup>) for chordal graphs, <i>O</i>(1.4776<sup><i>n</i></sup>) for weakly chordal graphs, <i>O</i>(1.4845<sup><i>n</i></sup>) for 4-chordal graphs, <i>O</i>(1.4887<sup><i>n</i></sup>) for circle graphs, and <i>O</i>(1.2273<sup>(1+&sqrt;1−2<i>c</i>)<i>n</i></sup>) for <i>c</i>-dense graphs.
Role of Temporal Processing Stages by Inferior Temporal Neurons in Facial Recognition

In this review, we focus on the role of temporal stages of encoded facial information in the visual system, which might enable the efficient determination of species, identity, and expression. Facial recognition is an important function of our brain and is known to be processed in the ventral visual pathway, where visual signals are processed through areas V1, V2, V4, and the inferior temporal (IT) cortex. In the IT cortex, neurons show selective responses to complex visual images such as faces, and at each stage along the pathway the stimulus selectivity of the neural responses becomes sharper, particularly in the later portion of the responses. In the IT cortex of the monkey, facial information is represented by different temporal stages of neural responses, as shown in our previous study: the initial transient response of face-responsive neurons represents information about global categories, i.e., human vs. monkey vs. simple shapes, whilst the later portion of these responses represents information about detailed facial categories, i.e., expression and/or identity. This suggests that the temporal stages of the neuronal firing pattern play an important role in the coding of visual stimuli, including faces. This type of coding may be a plausible mechanism underlying the temporal dynamics of recognition, including the process of detection/categorization followed by the identification of objects. Recent single-unit studies in monkeys have also provided evidence consistent with the important role of the temporal stages of encoded facial information. For example, view-invariant facial identity information is represented in the response at a later period within a region of face-selective neurons. Consistent with these findings, temporally modulated neural activity has also been observed in human studies. These results suggest a close correlation between the temporal processing stages of facial information by IT neurons and the temporal dynamics of face recognition.
FUNDAMENTAL PROPERTIES OF ASPHALTS AND MODIFIED ASPHALTS, VOLUME I: INTERPRETIVE REPORT

The Superpave binder specification developed during the Strategic Highway Research Program (SHR)) from 1987-1993 classifies construction grade asphalts into rheologically similar groups. All asphalts in a given grade have the same rheological properties to within 6 deg C. The mission of this project was to improve the understanding of the expected performance of petroleum asphalts under service conditions. These conditions include physical behavior of thin asphalt films in contact with aggregate, rheology and oxidative aging of wet asphalt, behavior of asphalt after extended aging, and propensity of asphalt films to reconsolidate ("heal") after microcracking. These phenomena are not described by the current binder specification. The results of said exposures are included in this document and have been used to produce a comprehensive chemical model of petroleum asphalt. Finally, the results have been used to develop new analytical methods that improve the capability to predict performance of asphalt in roadway service. These 16 new tests are described in Volume II of this report.
Comments on: Association Study between Coronary Artery Disease and rs1333049 and rs10757274 Polymorphisms at 9p21 Locus in South-West Iran

Genotyping was done using ARMS-PCR for rs1333049 and rs10757274 in their study. When we first looked at the genotype frequencies, we observed a substantial excess of heterozygote subjects for both SNPs. Specifically, the relative excess of heterozygosity (REH) (2), a measure for the strength of deviation from Hardy-Weinberg equilibrium (HWE), was approximately 137% for rs1333049 in controls (REH=2.3688, Table 1). In contrast, we did not observe any deviation from HWE in our own studies (3, 4).
Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain

Background and Objective: The reactive oxygen mechanisms associated with cell damage after photodynamic therapy (PDT) may be exploited to enhance tumor destruction. Pharmacological reduction of glutathione (GSH), an inhibitor of reactive oxygen species, can be induced by administration of buthionine sulfoximine (BSO).
Sustained effects of once-a-week gait training with hybrid assistive limb for rehabilitation in chronic stroke: case study

[Purpose] The purpose of this study was to investigate the accumulated and sustained effects of once-a-week gait training with a powered exoskeleton suit, Hybrid Assistive Limb, in a subject with chronic stroke. [Subject and Methods] The subject was a woman in her early sixties who had stroke onset approximately 5 years ago. A single-case ABA design was used. A 2-month baseline period was followed by an 8-week period of weekly gait training and a subsequent 2-month follow-up period. Throughout the study period, she underwent conventional physiotherapy. Outcome measures were the 10-meter walking test, timed up and go test, functional reach test, two-step test, and Berg Balance Scale. [Results] Significant improvements were seen in all outcome measures during the gait training period. Improvements in all outcome measures except walking speed were maintained at follow-up. [Conclusion] Continued gait training with Hybrid Assistive Limb once a week can improve gait and balance performance in patients with chronic stroke, and these improvements are maintained at least for two months.
Energy measurement of web service

In the current web service, a lot of interactive and multimedia contents are used for delivering information and entertainments. In particular, Adobe Flash, a Rich Internet Application (RIA) technology, is popular for publishing contents, advertisements, and multimedia on the web. Flash is widely accepted on many websites, because it provides attractive user interfaces, including animation, video, and interactivity for web pages. However, Flash has significant influence on the energy consumption indebted to its resource-intensive characteristics and its broad usage. In this paper, we investigate how energy can be wasted by heavy contents on websites, and explain the projected global energy consumption of web contents. Based on an energy consumption rating model for websites, we present how we can save energy if we modify the web content format without any change in software or hardware.
Evaluating safety and efficacy of rabbit antithymocyte globulin induction in elderly kidney transplant recipients.

OBJECTIVES The optimal immunosuppression regimen for elderly kidney transplant recipients is poorly defined. We sought to evaluate the short-term efficacy and safety of thymoglobulin in geriatric recipients of deceased-donor kidneys. MATERIALS AND METHODS A single-center, retrospective analysis was undertaken between elderly (≥ 65 years) (n=137) and nonelderly (n=276) kidney transplant recipients who received rabbit antithymocyte globulin induction and calcineurin inhibitor, mycophenolic acid, and prednisone maintenance. RESULTS The mean age was 70 versus 52 years. Fewer elderly patients had an earlier transplant or panel reactive antibodies > 20%, but had more machine perfused, older, and extended criteria donor kidneys. Elderly patients received lower rabbit antithymocyte globulin (5.4 vs 5.6 mg/kg; P = .04) and initial mycophenolic acid doses (1620 vs 1774 mg; P = .002), and experienced less delayed graft function (31.1% vs 50.0%; P < .001). Death-censored graft survival and graft function at 3 years and biopsy-proven acute rejection at 1 year were comparable; however, there was lower 3-year patient survival in elderly patients. Donor age was the only factor associated with reduced patient survival. Rates of malignancy, infection, or thrombocytopenia were similar; however, leukopenia occurred less frequently in elderly patients (11.7% vs 19.9%; P = .038). CONCLUSIONS Elderly kidney transplant recipients receiving rabbit antithymocyte globulin did not experience different short-term graft survival, graft function or rates of infection, malignancy or hematologic adverse reactions than did nonelderly patients; they experienced fewer episodes of delayed graft function, but had lower 3-year patient survival.
IL22/IL-22R Pathway Induces Cell Survival in Human Glioblastoma Cells

Interleukin-22 (IL-22) is a member of the IL-10 cytokine family that binds to a heterodimeric receptor consisting of IL-22 receptor 1 (IL-22R1) and IL-10R2. IL-22R expression was initially characterized on epithelial cells, and plays an essential role in a number of inflammatory diseases. Recently, a functional receptor was detected on cancer cells such as hepatocarcinoma and lung carcinoma, but its presence was not reported in glioblastoma (GBM). Two GBM cell lines and 10 primary cell lines established from patients undergoing surgery for malignant GBM were used to investigate the expression of IL-22 and IL-22R by using quantitative RT-PCR, western blotting and confocal microscopy studies. The role of IL-22 in proliferation and survival of GBM cell lines was investigated in vitro by BrdU and ELISA cell death assays. We report herein that the two subunits of the IL-22R complex are expressed on human GBM cells. Their activation, depending on exogenous IL-22, induced antiapoptotic effect and cell proliferation. IL-22 treatment of GBM cells resulted in increased levels of phosphorylated Akt, STAT3 signaling protein and its downstream antiapoptotic protein Bcl-xL and decreased level of phosphorylated ERK1/2. In addition, IL-22R subunits were expressed in all the 10 tested primary cell lines established from GBM tumors. Our results showed that IL-22R is expressed on GBM established and primary cell lines. Depending on STAT3, ERK1/2 and PI3K/Akt pathways, IL-22 induced GBM cell survival. These data are consistent with a potential role of IL-22R in tumorigenesis of GBM. Since endogenous IL-22 was not detected in all studied GBM cells, we hypothesize that IL-22R could be activated by immune microenvironmental IL-22 producing cells.
Candid Covariance-Free Incremental Principal Component Analysis

Appearance-based image analysis techniques require fast computation of principal components of high-dimensional image vectors. We introduce a fast incremental principal component analysis (IPCA) algorithm, called candid covariance-free IPCA (CCIPCA), used to compute the principal components of a sequence of samples incrementally without estimating the covariance matrix (so covariance-free). The new method is motivated by the concept of statistical efficiency (the estimate has the smallest variance given the observed data). To do this, it keeps the scale of observations and computes the mean of observations incrementally, which is an efficient estimate for some well known distributions (e.g., Gaussian), although the highest possible efficiency is not guaranteed in our case because of unknown sample distribution. The method is for real-time applications and, thus, it does not allow iterations. It converges very fast for high-dimensional image vectors. Some links between IPCA and the development of the cerebral cortex are also discussed.
Randomized frameproof codes: Fingerprinting plus validation minus tracing

We propose randomized frameproof codes for content protection, which arise by studying a variation of the Boneh-Shaw fingerprinting problem. In the modified system, whenever a user tries to access his fingerprinted copy, the fingerprint is submitted to a validation algorithm to verify that it is indeed permissible before the content can be executed. We show an improvement in the achievable rates compared to deterministic frameproof codes and traditional fingerprinting codes. For coalitions of an arbitrary fixed size, we construct randomized frameproof codes which have an O(n2) complexity validation algorithm and probability of error exp(-Omega(n)), where n denotes the length of the fingerprints. Finally, we present a connection between linear frameproof codes and minimal vectors for size-2 coalitions.
Fractal reorientation clocks: Linking animal behavior to statistical patterns of search

The movement ecology framework depicts animal movement as the result of the combined effects of internal and external constraints on animal navigation and motion capacities. Nevertheless, there are still fundamental problems to understand how these modulations take place and how they might be translated into observed statistical properties of animal trajectories. Of particular interest, here, is the general idea of intermittence in animal movement. Intermittent locomotion assumes that animal movement is, in essence, discrete. The existence of abrupt interruptions in an otherwise continuous flow of movement allows for the possibility of reorientations, that is, to break down previous directional memories of the trajectory. In this study, we explore the potential links between intermittent locomotion, reorientation behavior, and search efficiency. By means of simulations we show that the incorporation of Lévy intermittence in an otherwise nonintermittent search strongly modifies encounter rates. The result is robust to different types of landscapes (i.e., target density and spatial distribution), and spatial dimensions (i.e., 2D, 3D). We propose that Lévy intermittence may come from reorientation mechanisms capable of organizing directional persistence on time (i.e., fractal reorientation clocks), and we rationalize that the explicit distinction between scanning and reorientation mechanisms is essential to make accurate statistical inferences from animal search behavior. Finally, we provide a statistical tool to judge the existence of episodic and strong reorientation behaviors capable of modifying relevant properties of stochastic searches, ultimately controlling the chances of finding unknown located items.
Compatibility

Response to our new department is very gratifying, with two interesting papers to start out the first issue. These papers, "Hazards to Flammable Atmospheres and to Electroexplosive Devices Due to R.F. Radiation: Recent British Experience and the New Draft British Standards," by Dr. Excell, and. "Digital Models For Use in EMC ISP ICE Analysis," by Mr. Gabrielson and Mr. Carlsoµ_Jtr_t;. _g99d ! Xamples of what . we. wanted for . this . department. I . think you will find these papers interesting and-useful. Please keep them coming.
Heparanase is overexpressed in lung cancer and correlates inversely with patient survival

Heparanase is an endo‐β‐D‐glucuronidase that is capable of cleaving heparan sulfate (HS) side chains at a limited number of sites, yielding HS fragments of still appreciable size (approximately 5‐7 kDa). Heparanase activity has been detected frequently in several cell types and tissues. Heparanase activity correlates with the metastatic potential of tumor‐derived cells, a correlation that has been attributed to enhanced cell dissemination as a consequence of HS cleavage and remodeling of the extracellular matrix barrier.
HOMOLOGICAL STABILITY FOR UNORDERED CONFIGURATION SPACES

This paper consists of two related parts. In the first part we give a self-contained proof of homological stability for the spaces C_n(M;X) of configurations of n unordered points in a connected open manifold M with labels in a path-connected space X, with the best possible integral stability range of 2* \leq n. Along the way we give a new proof of the high connectivity of the complex of injective words. If the manifold has dimension at least three, we show that in rational homology the stability range may be improved to * \leq n. In the second part we study to what extent the homology of the spaces C_n(M) can be considered stable when M is a closed manifold. In this case there are no stabilisation maps, but one may still ask if the dimensions of the homology groups over some field stabilise with n. We prove that this is true when M is odd-dimensional, or when the field is F_2 or Q. It is known to be false in the remaining cases.