Miracle-dz/UniFAR-FTUs huggingface dataset:
Cross-layer resource allocation for integrated Voice/Data traffic in wireless cellular networks

A major task in next-generation wireless cellular networks is provisioning of quality of service (QoS) over the bandwidth limited and error-prone wireless link. In this paper, we propose a cross-layer design scheme to provide QoS for voice and data traffic in wireless cellular networks with differentiated services (DiffServ) backbone. The scheme combines the transport layer protocols and link layer resource allocation to both guarantee the QoS requirements in the transport layer and achieve efficient resource utilization in the link layer. Optimal resource allocation problems for voice and data flows are formulated to guarantee pre-specified QoS with minimal required resources. For integrated voice/data traffic in a cell, a hybrid time-division/code-division medium access control (MAC) scheme is presented to achieve efficient multiplexing. Theoretical analysis and simulation results demonstrate the effectiveness of the proposed cross-layer approach.
News from the community

This article examines the emergence of new, inter-local spaces of news production and consumption, drawing on extensive fieldwork and interviews with community reporters trained by a community reporter organisation based in the north of England. Practices of news production and content generation are focused on people's own communities and they are underpinned by an ethos of production, which is grounded in a critical consumption of news and collective processes of skill acquisition. Through an analysis of motivations and practices, we account for the values that sustain community reporter communities and discuss how such practices, while emerging from the place of local community, also extend across wider communities of interest. It is suggested that an evolving practice of skill sharing and mutual recognition could potentially stimulate the regrowth of democratic values.
Implicit learning of L2 word stress regularities

This article reports an experiment on the implicit learning of second language stress regularities, and presents a methodological innovation on awareness measurement. After practising two-syllable Spanish words, native Cantonese speakers with English as a second language (L2) completed a judgement task. Critical items differed only in placement of stress. We assessed participants’ awareness of the hidden stress regularities by verbal reports and a novel methodology: inclusion–exclusion production tasks adapted from Jacoby (1991) and from Destrebecqz and Cleeremans (2001). Participants who remained unaware of the underlying regularities nevertheless performed significantly above chance in identifying correctly pronounced novel words. We conclude that L2 word stress regularities may be learnt implicitly.
EMOTIONS AND COMPLAINING BEHAVIOR FOLLOWING SERVICE FAILURE

One feature of a democratic society is voice, especially the freedom to dissent. One form of dissent of relevance to organizational scholars is complaining, whether it be complaints from employee stakeholder groups or customer stakeholder groups. Despite the increased ability that the knowledge economy provides for people of all walks of life and nationalities to voice complaint, little is known about the antecedents and consequences of complaining. This paper addresses this issue with respect to customers’ response to service failures. Specifically, this paper develops a conceptual model for service settings building upon a model of emotional and cognitive response formation to an affective event (Hartel, McColl-Kennedy & Bennett, 2002), and its source theory, Weiss and Cropanzano’s (1995) Affective Events Theory (AET). We argue that when a service failure occurs, a number of cognitive and affective responses take place in consumers. The proposed model aims to operationalize affective responses to service failures in the marketplace. ‘Affective response’ refers to cognitive, emotional, behavioral and neuropsychological responses to emotional events. As such, the model makes explicit the relationships between and factors within each of these domains of affect expression. This paper is a work in progress. Material in the paper cannot be used without permission of the author.
Game Play Participation of Amotivated Students During Sport Education

Sport Education has embedded pedagogical strategies proposed to reduce the prevalence of amotivation in physical education. The purpose of this study was to provide an examination of the game play participation rates of amotivated students within a Sport Education season. A sample of 395 high school students participated in a season of team handball. A multistep cluster analysis approach revealed three motivational profiles: amotivated, moderate and high clusters. A priori analyses revealed differences in perceived effort, enjoyment, and need satisfaction across the three profile groups. Game play participation rates coded throughout the season revealed no significant differences in ball engagement or success rates across motivational profile groups. A significant difference occurred in active game participation between the high and amotivated students. Results suggest that Sport Education elicits a level of inclusive game play participation across students of different motivational profiles.
Comment: Microarrays, Empirical Bayes and the Two-Groups Model

Efron has given us a comprehensive and thoughtful review of his approach to large-scale testing stemming from the challenges of analyzing microarray data. Addressing the microarray challenge right from the emergence of the technology, and adapting the point of view on multiple testing that emphasizes the false discovery rate, Efron’s contributions in both fields have been immense. In the discussed paper he reviews philosophy, motivation, methodologies and even practicalities, and along this process gives us a view of the field of statistics from an eagle’s eye. A thorough discussion of such a work is a major undertaking. Instead, I shall first comment on five issues and then discuss new directions for research on largescale multiple inference that bear on Efron’s review. The scope of the review challenges a discussant to try and address some of the issues raised from a broader point of view. I shall give it a try.
Adolescent Use of Mobile Phones for Calling and for Sending Text Messages After Lights Out: Results from a Prospective Cohort Study with a One-Year Follow-Up

THE USE OF THE MODERN MEANS OF INTERPERSONAL AND MASS COMMUNICATION HAS BECOME AN ESSENTIAL PART OF BEING YOUNG. CHILDREN'S bedrooms are connected to global networks through internet access and mobile phones.1 Heavy use of television (TV), internet and computer games have been linked to reduced time in bed2 and to sleep disturbances3 although adolescents often claim they need these media as “sleep aids. ”4 Even when they sleep the interplay between media and sleep does not cease. Playing computer games has been shown to shorten REM sleep in adults,5 and many adolescents report dreaming about what they saw on TV or in a computer game.6 Little is known about the potential impact of the mobile phone on sleep. One brief cross sectional study found that up to a third of 13- and 15-year-old children in Belgium reported receiving incoming messages after lights out at least once a month.7 Other existing sleep studies only dealt with biological effects of emissions.8 The electromagnetic fields produced by mobile phones, for instance, may have an effect on the sleep electroencephalogram,9 and evening exposure to mobile phone emissions may affect melatonin production.10 Observational studies of mobile phone behaviors of adolescents suggest that they engage in a lot of calling and text messaging behaviors. An Italian study described “ringing,” a practice involving one adolescent dialing another whereby the call is interrupted before the other person is able to answer it. The other telephone thus displays the message that a call from a particular number failed, which is a way of telling that person “I was thinking of you. ” Interestingly, neither person is charged for this communication.11 Even more elaborate is “bombing” in which the number of times the phone rings signals what the caller is trying to convey, a technique adolescents use to tell each other what time they leave for school or to answer messages (by common agreement one ring may mean “yes” and two may mean “no”). 12 Much of the use of the mobile phone involves the simple pleasure of being permanently connected to a group of people: one popular pastime is sending “chain messages” to a number of friends.12 These behaviors appear to be common among all adolescents. A comparison of studies from several countries showed that there are many similarities between mobile phone cultures of young people in several European countries.12 The aim of the current study was to chart the extent to which adolescents use their mobile phone for sending and/or receiving text messages and/or calls after lights out and to examine whether this predicted higher levels of tiredness.
Is this really what women want? An analysis of Fifty Shades of Grey and modern feminist thought

The article briefly presents a paradox generated by the unprecedented sales of the Fifty Shades of Grey trilogy by E.L. James and explores some pros and cons of this new literary genre (‘erotic fiction’), while examining the discourse of polarised reactions thereto. Attention is given to Freud's unanswered question, cited in the context of the difficulties associated with defining women's roles as relative to those of men. This context reflects the patriarchal basis of political structures that have been grounded in the accepted subordination of women. The origins of feminism were driven by these political concerns and will be used as perspectives from which to understand the ‘Fifty Shades’ phenomenon. ‘First wave’ feminism succeeded in instantiating some public-legal equality for women and gave rise to the ‘second wave’ that sought to address inequality between the sexes in all areas of social interaction. However, both did not succeed in eradicating troublesome patriarchal stereotypes that persist today.
Musket: a multistage k-mer spectrum-based error corrector for Illumina sequence data

MOTIVATION The imperfect sequence data produced by next-generation sequencing technologies have motivated the development of a number of short-read error correctors in recent years. The majority of methods focus on the correction of substitution errors, which are the dominant error source in data produced by Illumina sequencing technology. Existing tools either score high in terms of recall or precision but not consistently high in terms of both measures. RESULTS In this article, we present Musket, an efficient multistage k-mer-based corrector for Illumina short-read data. We use the k-mer spectrum approach and introduce three correction techniques in a multistage workflow: two-sided conservative correction, one-sided aggressive correction and voting-based refinement. Our performance evaluation results, in terms of correction quality and de novo genome assembly measures, reveal that Musket is consistently one of the top performing correctors. In addition, Musket is multi-threaded using a master-slave model and demonstrates superior parallel scalability compared with all other evaluated correctors as well as a highly competitive overall execution time. AVAILABILITY Musket is available at http://musket.sourceforge. net.
In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma

Pardaxin (H-GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE-OH), a 33-amino-acid polypeptide, is an antimicrobial peptide (AMP) isolated from the marine fish species Pardachirus marmoratus. Pardaxin shows antibacterial and antitumor activities. However, pardaxin-induced inhibition of oral cancer and the mechanism of tumor reduction in buccal pouch carcinogenesis after pardaxin painting remain undetermined. Additionally, the toxic effects of pardaxin on normal tissue remain unclear. The present study investigated the anticancer activity of pardaxin in oral squamous cell carcinoma (OSCC) cells in the hamster buccal pouch model with or without 7,12-dimethylbenz[a]anthracene (DMBA) pretreatment. This is the first study to confirm the effects of pardaxin on normal tissue and its nontoxic effects in vivo. Cell viability assays and colony formation tests in OSCC cell lines (SCC-4) demonstrated that pardaxin reduced cell viability in a dose-dependent manner. Immunofluorescence staining of cleaved caspase-3 in SCC-4 cells revealed that expression of activated caspase-3 in SCC-4 cells significantly increased after 24-h treatment with pardaxin. Additionally, a cell cycle analysis indicated that pardaxin treatment resulted in the cell cycle arrest of SCC-4 cells in the G2/M phase, thereby limiting cell proliferation. Furthermore, pardaxin treatment substantially alleviated carcinogenesis in the DMBA-induced hamster buccal pouch model by lowering prostaglandin E2 levels. These results suggest that pardaxin is a potential marine drug for adjuvant chemotherapy for human OSCC and oral cancer.
Soft-Boiled Masculinity

This article examines the tensions in the identities of men who belong to the Promise Keepers (PK) movement by uncovering the social conditions that lead men to rethink gender and racial ideologies. Using participant observation and in-depth interviews, the author draws on gender and social movement scholarship to reveal how contradictory gender and racial ideologies shape PKs' identities. Furthermore, the PKs' impact on gender and race relations is also contradictory. PK fosters men's growth on an interactional level, allowing men to embrace a more expressive and caring masculinity that includes cross-racial bonding. Simultaneously, however, PK ignores, and indirectly reinforces, the structural conditions that underpin gender and racial privilege among white men.
Local Overexpression of Toll-Like Receptors at the Vessel Wall Induces Atherosclerotic Lesion Formation: Synergism of TLR2 and TLR4

Objective—Atherosclerosis is now considered as a chronic inflammatory disease, and inflammation is closely related to immune systems, which consist of innate-immunity and adaptive-immunity. Recently, toll-like receptors (TLRs) have been identified as key components of innate-immunity. We examined the role of local expressions of TLRs at the vessel wall in atherosclerosis. Methods and Results—We transfected cDNA encoding human TLR2 and TLR4 into the carotid arterial vessel wall of rabbits fed high-cholesterol diets with the use of HVJ-liposome. The rabbits were transfected with (1) pCMV-&bgr;-gal, (2) empty vector, (3) TLR2, (4) TLR4, (5) TLR2+4. X-gal staining and immunohistochemical analysis showed that the transfected plasmids were mainly expressed in the media. Neither TLR2 nor TLR4 transfection induced significant augmentation of atherosclerosis. Transfection of TLR2- and TLR4-containing HVJ synergistically accelerated atherosclerosis and increased expressions of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and MCP-1. Moreover, transfection of TLR2 and TLR4 resulted in synergistic activation of NF-&kgr;B at the vessel wall in vivo, and in vascular smooth muscle cells in vitro. Conclusions—Expressions of both TLR2 and TLR4 at the vessel wall synergistically accelerated atherosclerosis. The present study revealed the role of TLRs expressed locally at the vessel wall in the early stage of atherosclerosis.
Immunoglobulin Mto-Immunoglobulin G Anti-Human Leukocyte Antigen Class II Antibody Switching in Cardiac Transplant Recipients Is Associated With an Increased Risk of Cellular Rejection and Coronary Artery Disease

Background—Activation of T cells induces immunoglobulin (Ig)M-to-IgG B-cell isotype switching via costimulatory regulatory pathways. Because rejection of transplanted organs is preceded by alloantigen-dependent T-cell activation, we investigated whether B-cell isotype switching could predict acute cellular rejection and the subsequent development of transplantation-related coronary artery disease (TCAD) in cardiac transplant recipients. Methods and Results—Among 267 nonsensitized heart transplant recipients, switching from IgM to IgG anti-human leukocyte antigens (HLA) antibodies directed against class II but not against class I antigens was associated with a shorter duration to high-grade rejection, defined as International Society for Heart and Lung Transplantation grade 3A or higher (P 0.001), a higher cumulative rejection frequency (P 0.002), accelerated development of TCAD (P 0.04), and decreased late survival (P 0.03). Conversely, the persistence of IgM anti-HLA antibodies against class II but not against class I antigens for 30 days and the lack of IgG isotype switching were associated with protection against both acute rejection (P 0.02) and TCAD (P 0.05). Alloisotype switching coincided with T-cell activation, as evidenced by increased serum levels of soluble CD40 ligand costimulatory molecules. Finally, a case-control study showed that reduction of cardiac allograft rejection by mycophenolic acid was accompanied by reduced CD40 ligand serum levels and the prevention of IgM-to-IgG anti-HLA class II antibody switching. Conclusions—T-cell–dependent B-cell isotype switching and the consequent production of IgG anti-HLA class II antibodies are strongly correlated with acute cellular rejection, a high incidence of recurrent rejections, TCAD, and poor long-term survival. Detecting this isotype switch is a clinically useful surrogate marker for in vivo T-cell activation and may provide a noninvasive approach for monitoring the efficacy of T-cell targeted immunosuppressive therapy in heart transplant recipients. (Circulation. 2005;112:2468-2476.)
THE PROCESS OF IMMEDIACY IN BRIEF PSYCHOTHERAPY: COMPONENTS, EVENTS AND RELATIONSHIP TO IN-SESSION CLIENT CHANGE WITHIN A SINGLE CASE

Title of dissertation: THE PROCESS OF IMMEDIACY IN BRIEF PSYCHOTHERAPY: COMPONENTS, EVENTS AND RELATIONSHIP TO IN-SESSION CLIENT CHANGE WITHIN A SINGLE CASE Laura B. Kasper, Doctor of Philosophy, 2005 Dissertation directed by: Professor Clara E. Hill Department of Psychology This study examined the process of immediacy, defined as conversations insession about the immediate client-therapist relationship. Therapist immediacy interventions, the relationship between immediacy and client involvement, and immediacy events within a single-case were examined. The client was a 24-year-old Middle-Eastern female and the therapist was a 51-year-old Caucasian male. The psychotherapy was interpersonal and included 12 total weekly sessions. Psychotherapy outcome was measured by the OQ 45.2 (Outcome Questionnaire 45.2), IIP-32 (Inventory of Interpersonal Problems-32), and the SUIP-R (Self-Understanding of Interpersonal Patterns – Revised). Session measures included the SEQ-D (Session Evaluation Questionnaire – Depth) and the WAI-S (Working Alliance Inventory – Short). Immediacy and Client Involvement were both judge rated measures and coded based on speaking turns. Immediacy events were identified and analyzed by two judges. Results indicated the sessions were deep and the working alliance was strong overall. The client ended treatment with more symptoms and interpersonal problems, but with a greater understanding of her interpersonal patterns. Results also indicated the therapist used one immediacy intervention, inquiry about the client-therapist relationship, most often and the other two immediacy interventions, self-involving statements and feedback, much less frequently. The client appeared more involved in session when the therapist inquired about their relationship and appeared less involved in session when the therapist used self-involving statements. Client involvement was slightly higher before and after immediacy events than during immediacy events. Nine types of immediacy events were found, none of which involved difficult events (i.e., misunderstandings, alliance ruptures). Events fell into two categories: process and here-and-now events. Process events included reflecting on treatment and the client-therapist-relationship, and drawing the parallel between therapy and outside relationships. Process events occurred throughout treatment. Here-and-now events included the therapist’s expression of disappointment, care, and sadness in relation to the client and a desire to connect with the client. There was a changing pattern over time in the occurrence of here-and-now events. The client had the strongest reactions after sessions to here-and-now events, but did not directly express these strong reactions to the therapist in session. Limitations and implications for practice and future research are discussed. THE PROCESS OF IMMEDIACY IN BRIEF PSYCHOTHERAPY: COMPONENTS, EVENTS, AND RELATIONSHIP TO IN-SESSION CLIENT CHANGE WITHIN A SINGLE CASE
Protospacer recognition motifs Mixed identities and functional diversity

*Correspondence to: Roger A. Garrett; Email: garrett@bio.ku. dk Protospacer adjacent motifs (PAMs) were originally characterized for CRISPR-Cas systems that were classified on the basis of their CRISPR repeat sequences. A few short 2–5 bp sequences were identified adjacent to one end of the protospacers. Experimental and bioinformatical results linked the motif to the excision of protospacers and their insertion into CRISPR loci. Subsequently, evidence accumulated from different virusand plasmid-targeting assays, suggesting that these motifs were also recognized during DNA interference, at least for the recently classified type I and type II CRISPR-based systems. The two processes, spacer acquisition and protospacer interference, employ different molecular mechanisms, and there is increasing evidence to suggest that the sequence motifs that are recognized, while overlapping, are unlikely to be identical. In this article, we consider the properties of PAM sequences and summarize the evidence for their dual functional roles. It is proposed to use the terms protospacer associated motif (PAM) for the conserved DNA sequence and to employ spacer acqusition motif (SAM) and target interference motif (TIM), respectively, for acquisition and interference recognition sites.