Miracle-dz/UniFAR-FTUs huggingface dataset:
Class-Wise Supervised Hashing with Label Embedding and Active Bits

Learning to hash has become a crucial technique for big data analytics. Among existing methods, supervised learning approaches play an important role as they can produce compact codes and enable semantic search. However, the size of an instance-pairwise similarity matrix used in most supervised hashing methods is quadratic to the size of labeled training data, which is very expensive in terms of space, especially for a large-scale learning problem. This limitation hinders the full utilization of labeled instances for learning a more precise hashing model. To overcome this limitation, we propose a class-wise supervised hashing method that trains a model based on a class-pairwise similarity matrix, whose size is much smaller than the instance-pairwise similarity matrix in many applications. In addition, besides a set of hash functions, our proposed method learns a set of classwise code-prototypes with active bits for different classes. These class-wise code-prototypes can help to learn more precise compact codes for semantic information retrieval. Experimental results verify the superior effectiveness of our proposed method over other baseline hashing methods.
Gender differences in blood pressure and heart rate in spontaneously hypertensive and Wistar‐Kyoto rats

1. In general, premenopausal women are known to have lower blood pressure than men and animal models have shown a similar sexual dimorphism. However, many studies in animals have been performed using anaesthetized or restrained models. Current experiments were conducted to investigate the relationships among resting heart rate, blood pressure and gender in conscious, unrestrained normotensive Wistar‐Kyoto (WKY) rats and spontaneously hypertensive rats (SHR).
GENACE: an efficient cultural algorithm for solving the flexible job-shop problem

This work presents an efficient methodology called GENACE for solving the flexible job-shop scheduling problem (or FJSP) with recirculation. We show how CDRs are used to solve the FJSP with recirculation by themselves and to provide a bootstrapping mechanism to initialize GENACE. We then adopt a cultural evolutionary architecture to maintain knowledge of schemata and resource allocations learned over each generation. The belief spaces influence mutation and selection over a feasible chromosome representation. Experimental results show that GENACE obtains better upper bounds for 11 out of 13 benchmark problems, with improvement factors of 2 to 48 percent when compared to results by Kacem et al. (2002), Brandimarte (1993) and of using CDRs alone.
Impact of the Combined Use of Opioids and Surgical Procedures on Workers' Compensation Cost Among a Cohort of Injured Workers in the State of Louisiana

Objective:To determine the impact of surgical procedures and opioids on workers' compensation claim cost. Methods:A cohort of 11,394 lost time claims filed with the Louisiana Workers' Compensation Corporation from 1999 to 2002 was followed for 7 years. Results:Controlling for gender, attorney involvement, and claim duration, multivariate logistic regression analysis indicated that odds ratios (ORs) for a catastrophic claim (final cost ≥ $100,000) associated with short-acting and long-acting opioids (vs no opioids) were 4.28 and 12.19. The ORs for catastrophic claims associated with a spinal surgical procedure or spinal fusion (vs no procedure) were 4.27 and 11.40. Spinal surgical procedures plus opioid use significantly increased the OR for catastrophic claims; for example, spinal fusion plus long-acting opioids had an OR of 138.96. Conclusion:Spinal surgery and opioid utilization are associated with catastrophic claim costs.
The Existential Function of Close Relationships: Introducing Death Into the Science of Love

Originally, terror management theory proposed two psychological mechanisms in dealing with the terror of death awareness-cultural worldview validation and self-esteem enhancement. In this article, we would like to promote the idea of close relationships as an additional death-anxiety buffering mechanism and review a growing body of empirical data that support this contention. Based on a comprehensive analysis of the sociocultural and personal functions of close relationships, we formulate two basic hypotheses that have received empirical support in a series of experimental studies. First, death reminders heighten the motivation to form and maintain close relationships. Second, the maintenance of close relationships provides a symbolic shield against the terror of death, whereas the breaking of close relationships results in an upsurge of death awareness. In addition, we present empirical evidence supporting the possibility that close relationships function as a related yet separate mechanism from the self-esteem and cultural worldview defenses.
Neurotoxic lesions of ventrolateral prefrontal cortex impair object-in-place scene memory

Disconnection of the frontal lobe from the inferotemporal cortex produces deficits in a number of cognitive tasks that require the application of memory‐dependent rules to visual stimuli. The specific regions of frontal cortex that interact with the temporal lobe in performance of these tasks remain undefined. One capacity that is impaired by frontal–temporal disconnection is rapid learning of new object‐in‐place scene problems, in which visual discriminations between two small typographic characters are learned in the context of different visually complex scenes. In the present study, we examined whether neurotoxic lesions of ventrolateral prefrontal cortex in one hemisphere, combined with ablation of inferior temporal cortex in the contralateral hemisphere, would impair learning of new object‐in‐place scene problems. Male macaque monkeys learned 10 or 20 new object‐in‐place problems in each daily test session. Unilateral neurotoxic lesions of ventrolateral prefrontal cortex produced by multiple injections of a mixture of ibotenate and N‐methyl‐d‐aspartate did not affect performance. However, when disconnection from inferotemporal cortex was completed by ablating this region contralateral to the neurotoxic prefrontal lesion, new learning was substantially impaired. Sham disconnection (injecting saline instead of neurotoxin contralateral to the inferotemporal lesion) did not affect performance. These findings support two conclusions: first, that the ventrolateral prefrontal cortex is a critical area within the frontal lobe for scene memory; and second, the effects of ablations of prefrontal cortex can be confidently attributed to the loss of cell bodies within the prefrontal cortex rather than to interruption of fibres of passage through the lesioned area.
OLS and GWR LUR models of wildfire smoke using remote sensing and spatiotemporal data in Alberta

Wildfire smoke from forest fire is a major source of air pollution in Canadian cities. Wildfire smoke includes different types of gases and particles that adversely affect human health. Particulate Matter (PM), as the predominant pollutant in wildfire smoke, poses the greatest risk to human health. Accurate investigation of wildfirerelated PM2.5 is critical to understand health-related effects. This research investigated PM2.5 concentration of wildfire smoke drifting over parts of Alberta in August 2017 from British Columbia, Montana, Idaho, and as far away as Washington State. We developed OLS and GWR land use regression models, which integrate the use of MODIS Aerosol Optical Depth data and temporal indicators to model PM2.5 concentration. The results provide estimates of PM2.5 at finer spatial resolution than ground-based records; these estimates could aid epidemiological studies to assess the health effects of wildfire smoke.
Social Networking Smartphone Applications and Sexual Health Outcomes among Men Who Have Sex with Men

Several smartphone applications (apps) designed to help men who have sex with men (MSM) find casual sexual partners have appeared on the market recently. Apps of this nature have the potential to impact sexual health and behavior by providing constant access to a large supply of available partners. In this study, the sexual health history, behavior, and personality of MSM who use these apps was compared to MSM who meet partners in other ways. A sample of 110 adult MSM was recruited online to complete a cross-sectional survey. All participants were either single or involved in a non-exclusive romantic relationship. There were no statistically significant differences between app users and non-users in frequency of insertive or receptive anal sex without a condom. However, app users reported significantly more sexual partners and had a higher prevalence of ever being diagnosed with an STI than did non-users. App users did not differ from non-users on any demographic or personality variables (including erotophilia, sensation seeking, and self-control); however, when adjusting lifetime total sex partners for those met specifically through apps, app users still had significantly more partners. This pattern of results suggests that app users may be more sexually active in general. More work is needed to fully understand the association between this emerging technology and potential sexual health risks.
The Antidepressant Effect of Linseed and Olive Oils on Reserpine-Induced Depressed Male Albino Rats

The present study aimed to investigate the antidepressant potential of linseed and olive oils on reserpine model of depression in male rats through their effects on the levels of monoamine neurotransmitters and behavioral changes induced by reserpine. This study was conducted on 60 male albino rats divided randomly into six main groups: the first is the control group that included normal rats; the second and third groups contained normal rats orally administrated with linseed and olive oils, respectively; the fourth or depressed group contained animals treated with reserpine (ip) alone; and the fifth and sixth groups included depressed animals treated orally with linseed and olive oils, respectively. Neurochemical monoamines such as serotonin, norepinephrine and dopamine were measured in cerebral cortex and hippocampus brain areas) and Behavioral studies (immobility time) were measured to evaluate the antidepressant effect of both oils. The obtained results demonstrated that daily injection of rats with reserpine resulted in a significant elevation in the immobility time matched with a significant decrease in the cerebral cortex and hippocampal monoamine neurotransmitters levels; while daily treatment of the reserpinized rats with both linseed and olive oils returned significantly the decrease of both cortical and hippocampal monoamine neurotransmitters levels to approach the normal control values coupled with significant reduction in the immobility time. Results indicated that increased immobility time induced by reserpine was restored into normal control levels by linseed and olive oils treatment for 30 days. It could be concluded that the depression deterioration markers induced in rats by reserpine can be restored significantly by either linseed or olive oils via their antioxidant capacity as well as anti depressant potential of their constituents.
Childhood anxiety and memory performance: A comparison of systemic and processing accounts /

Recent cognitive theories suggest that anxiety is associated with a memory bias toward the disproportionate recall o f threatening information. Although studies of adults provide some evidence for such a bias, they have yielded inconsistent and contradictory results. These data are further limited by a global, unitary conceptualization of memory or examination of a dichotomous implicit-explicit memory distinction. Recent advances in memory research allow for an increasingly fine-grained analysis of the relationship between anxiety and memory. Exclusive reliance on implicit and explicit memory tasks precludes determining whether memory performance is due to a particular type of processing (i.e., perceptual vs. conceptual) or memory system (i.e., declarative vs. procedural). The present study examined the relationship between childhood anxiety and memory in a sample of 160 highand low-trait-anxious sixth through eighth grade children. Participants were randomly assigned to one of four experimental conditions that crossed processing type with memory system (i.e., perceptual-procedural, perceptualdeclarative, conceptual-procedural, conceptual-declarative). Results indicated that anxiety significantly interacted with processing type in predicting a memory bias toward negative relative to neutral information, whereas anxiety interacted with memory system in predicting a bias toward positive relative to neutral information. Specifically, the lowand high-anxious groups did not differ in their negative memory bias on perceptual processing tasks, but high-anxious children displayed a greater bias toward negative information on conceptual processing tasks than low-anxious children. Further, relative to low-anxious children, high-anxious children were biased away from recalling positive information on declarative system tasks, but were biased toward recalling positive information on procedural system tasks. These findings highlight the complexity and multidimensionality of relationships among childhood anxiety, the emotional valence of stimuli, types of cognitive processing, and memory systems in contributing to information-processing biases of children's memorial functioning.
Evaluation of Zuckerman-Kuhlman Personality Questionnaire-50-CC in Serbian culture

The main purpose of this research was to evaluate dimensions of the Zuckerman-Kuhlman Personality Questionnaire-50-CC (ZKPQ-50-CC) in the Serbian culture in the light of some of the basic assumptions of the alternative five-factor model – the cross-cultural stability, construct validity and heritability. The study had two parts. The aim of the first study is to evaluate the replicability of the alternative FFM in a Serbian sample (N = 1155). Three structural models were tested using confirmatory factor analysis. The model which included correlated dimensions and four omitted items showed the best fit. The second study, conducted on a sample of 200 participants (90 male and 110 female), was set to test several models of relations between the alternative FFM and Eysenck's PEN model. Four models were tested using the structural equation modeling. The best- fitting model included three latent dimensions, which corresponded to PEN dimensions.
Health and Unemployment During Macroeconomic Crises

This paper shows that health is an important determinant of labor market vulnerability during large economic crises. Using data on adults during Sweden’s unexpected economic crisis in the early 1990s, we show that early and later life health are important determinants of job loss after the crisis, but not before. Adults who were born with worse health (proxied by birth weight) and those who experience hospitalizations (and especially so for mental health related issues) in the pre-crisis period, are much more likely to lose their jobs and go on unemployment insurance after the crisis. These effects are concentrated in the private sector that happened to be more affected by the crisis. The results hold while controlling for individual education and occupational sorting prior to the crisis, and for controlling for family level characteristics by exploiting health differences within twin pairs. We conclude that poor health (both in early life and as adults) is an important indicator of vulnerability during economic shocks.
Investment opportunity set and dividend policy in Malaysia : some evidence on the role of government ownership, family ownership, board size and board composition / Ravichandran K. Subramaniam.

Prior studies show that there is a negative association between IOS (Investment opportunity set) or growth opportunities and dividend payout. While there are several theories such as the signalling hypothesis, the tax hypothesis, free cash flow (FCF) hypothesis and the contracting hypothesis that maybe used to explain this relationship, the main theory suggested in the extant literature was Free Cash Flow Theory (FCF) by Smith and Watts (1992). According to the free cash flow theory, managers of firms with more growth opportunities or higher IOS (prospective investment opportunities and associated payoff distributions) are more likely to pay lesser dividends since these firms need the cash for growth opportunities. However, firms with low growth opportunities pay out more dividends since these firms have few opportunities to invest in positive net present value projects. In this study I re-examine whether this negative relationship exists in the Malaysian corporate sector. I examine Malaysian firms because it is a developing country and also because of the existence of a global decline in the propensity to pay dividends especially among firms incorporated in common law jurisdictions. Further I investigate whether corporate governance variables such as (1) government ownership (2) boardsize, (3) board composition and (4) family ownership affects the association between growth opportunities and dividend policies. I examine government ownership because there seemed to be a high concentration of government link companies among public listed companies. Board-size and board composition is examined to evaluate to what extent those corporate governance monitoring have an impact on dividend payouts. No known prior study has investigated whether these variables moderate the relationship between growth opportunities and dividend payout. Several hypotheses are developed to test these relationships. Using data from annual reports of Malaysian companies I expect to find that there is a negative association between growth opportunities and dividend payout in Malaysian firms thus confirming prior findings and FCF theory. Further I expect that the relationship should be weaker for government owned as there is some anecdotal evidence suggesting a positive association between ownership and dividends since firms with government ownership have relatively less difficulty raising funds to finance investments and can therefore afford to pay dividends. As for family owned businesses, the relationship would be weaker because of the high concentration of family ownership as family members are concerned about wealth transfer. The relationship for board-size and board composition is envisaged to be negatively related to growth opportunities.
Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy.

BACKGROUND Tumors with homologous recombination deficiency (HRD), such as BRCA1-associated breast cancers, are not able to reliably repair DNA double-strand breaks (DSBs) and are therefore highly sensitive to both DSB-inducing chemotherapy and poly (ADP-ribose) polymerase inhibitors. We have studied markers that may indicate the presence of HRD in HER2-negative breast cancers and related them to neoadjuvant chemotherapy response. PATIENTS AND METHODS Array comparative genomic hybridization (aCGH), BRCA1 promoter methylation, BRCA1 messenger RNA (mRNA) expression and EMSY amplification were assessed in 163 HER2-negative pretreatment biopsies from patients scheduled for neoadjuvant chemotherapy. RESULTS Features of BRCA1 dysfunction were frequent in triple-negative (TN) tumors: a BRCA1-like aCGH pattern, promoter methylation and reduced mRNA expression were observed in, respectively, 57%, 25% and 36% of the TN tumors. In ER+ tumors, a BRCA2-like aCGH pattern and the amplification of the BRCA2 inhibiting gene EMSY were frequently observed (43% and 13%, respectively) and this BRCA2-like profile was associated with a better response to neoadjuvant chemotherapy. CONCLUSIONS Abnormalities associated with BRCA1 inactivation are present in about half of the TN breast cancers but were not predictive of chemotherapy response. In ER+/HER2- tumors, a BRCA2-like aCGH pattern was predictive of chemotherapy response. These findings should be confirmed in independent series.
Therapy and Trauma The Effectiveness of Art Therapy in the Treatment of Traumatized Adults : A Systematic Review on Art

Art therapy has often been applied in the treatment of traumatized adults, and good results in clinical practice have been reported. However, although art therapy experts underline these benefits, the effectiveness of art therapy in trauma treatment has not been established by systematic review. The aim of this systematic review is to identify and evaluate empirical evidence of the effectiveness of art therapy for trauma treatment. As a result of the systematic review, six controlled, comparative studies on art therapy for trauma in adult patients were found. In half of the included studies, a significant decrease in psychological trauma symptoms was found in the treatment groups, and one study reported a significant decrease in depression. Although there are limitations in the number of included studies, the number of participants, the heterogeneity of included studies, and their methodological quality, the results contribute to insight into the effectiveness of art therapy in trauma treatment and form an evidence base for the urgent need for further research on art therapy and trauma treatment.
Targeted Disruption of the Intracellular Domain of Receptor FgfrL1 in Mice

FgfrL1 is the fifth member of the fibroblast growth factor receptor (Fgfr) family. Studies with FgfrL1 deficient mice have demonstrated that the gene plays an important role during embryonic development. FgfrL1 knock-out mice die at birth as they have a malformed diaphragm and lack metanephric kidneys. Similar to the classical Fgfrs, the FgfrL1 protein contains an extracellular part composed of three Ig-like domains that interact with Fgf ligands and heparin. However, the intracellular part of FgfrL1 is not related to the classical receptors and does not possess any tyrosine kinase activity. Curiously enough, the amino acid sequence of this domain is barely conserved among different species, with the exception of three motifs, namely a dileucine peptide, a tandem tyrosine-based motif YXXΦ and a histidine-rich sequence. To investigate the function of the intracellular domain of FgfrL1, we have prepared genetically modified mice that lack the three conserved sequence motifs, but instead contain a GFP cassette (FgfrL1ΔC-GFP). To our surprise, homozygous FgfrL1ΔC-GFP knock-in mice are viable, fertile and phenotypically normal. They do not exhibit any alterations in the diaphragm or the kidney, except for a slight reduction in the number of glomeruli that does not appear to affect life expectancy. In addition, the pancreas of both FgfrL1ΔC-GFP knock-in and FgfrL1 knock-out mice do not show any disturbances in the production of insulin, in contrast to what has been suggested by recent studies. Thus, the conserved motifs of the intracellular FgfrL1 domain are dispensable for organogenesis and normal life. We conclude that the extracellular domain of the protein must conduct the vital functions of FgfrL1.