Miracle-dz/UniFAR-FTUs huggingface dataset:
Ethical and political implications of the turn to stories in suicide prevention

Abstract:The stories of suicide attempt survivors are gaining broader currency in suicide prevention where they have the potential to provide privileged insights into experiences of suicide, strengthen prevention and intervention measures, and reduce discrimination and stigmatization. Stories of suicide, however, have a double-edged power insofar as their benefits are counterweighted by a number of acknowledged harms. Drawing on the literatures and methods of narrative, and in particular, narrative approaches to bioethics, I contend that suicide prevention organizations make possible yet constrain the creation of personal stories of suicide, shaping the discursive meanings of public stories of suicide while setting limits on which stories are valued, legitimized, and rendered intelligible. Personal stories of suicide serve as important sites of meaning-making, power, and social identity, yet they also reproduce and normalize particular ways of thinking, acting, and communicating that reinforce the institutional logics of suicidology. These have ethical and political force as they help to frame the ways suicide is understood, the ways it is subjectively experienced, and the ways it is responded to.
Anticipatory care planning and integration: a primary care pilot study aimed at reducing unplanned hospitalisation.

BACKGROUND Anticipatory care for older patients who are frail involves both case identification and proactive intervention to reduce hospitalisation. AIM To identify a population who were at risk of admission to hospital and to provide an anticipatory care plan (ACP) for them and to ascertain whether using primary and secondary care data to identify this population and then applying an ACP can help to reduce hospital admission rates. DESIGN AND SETTING Cohort study of a service intervention in a general practice and a primary care team in Scotland. METHOD The ACP sets out patients' wishes in the event of a sudden deterioration in health. If admitted, a proactive approach was taken to transfer and discharge patients into the community. Cohorts were selected using the Nairn Case Finder, which matched patients in two practices for age, sex, multiple morbidity indexes, and secondary care outpatient and inpatient activity; 96 patients in each practice were studied for admission rate, occupied bed days and survival. RESULTS Survivors from the ACP cohort (n = 80) had 510 fewer days in hospital than in the 12 months pre-intervention: a significant reduction of 52.0% (P = 0.020). There were 37 fewer admissions of the survivors from that cohort post-intervention than in the preceding 12 months, with a significant reduction of 42.5% (P = 0.002). Mortality rates in the two cohorts were similar, but the number of patients who died in hospital and the hospital bed days used in the last 3 months of life were significantly lower for the decedents with an ACP than for the controls who had died (P = 0.007 and P = 0.045 respectively). CONCLUSION This approach produced statistically significant reductions in unplanned hospitalisation for a cohort of patients with multiple morbidities. It demonstrates the potential for providing better care for patients as well as better value for health and social care services. It is of particular benefit in managing end-of-life care.
The psychometric characteristics of the Advanced Measures of Music Audiation in a region with strong non-Western music tradition

This study investigates the psychometric characteristics of Gordon’s Advanced Measures of Music Audiation (AMMA) in a region with strong non-Western music tradition. It also examines the possibility of measuring audiation with the modern psychometric theory. The AMMA test was administered to 513 students in the city of Ioannina and a number of villages in the region of Epirus in northwestern Greece. Nonlinear factor analysis based on tetrachoric correlation coefficients confirmed a tone and rhythm structure in AMMA according to the theory of Gordon. Cronbach’s alpha coefficients for the tone and rhythm factor scores were . 70 and . 61 correspondingly. The Kuder and Richardson’s (KR-20) reliability coefficient for the 30 items was . 55. A Rasch measurement model has a good fit. The analysis of the Rasch residuals has showed that the dimensions of AMMA do not distort the estimation of Rasch parameters. Further analysis of the 30 AMMA items has shown that they can be ordered in 10 levels of difficulty. The authors present items’ difficulty and persons’ level of audiation on the same interval scale and discuss the usefulness of the music ability tests that are based on aural stimuli.
Different Contributions of the Human Amygdala and Ventromedial Prefrontal Cortex to Decision-Making

The somatic marker hypothesis proposes that decision-making is a process that depends on emotion. Studies have shown that damage of the ventromedial prefrontal (VMF) cortex precludes the ability to use somatic (emotional) signals that are necessary for guiding decisions in the advantageous direction. However, given the role of the amygdala in emotional processing, we asked whether amygdala damage also would interfere with decision-making. Furthermore, we asked whether there might be a difference between the roles that the amygdala and VMF cortex play in decision-making. To address these two questions, we studied a group of patients with bilateral amygdala, but not VMF, damage and a group of patients with bilateral VMF, but not amygdala, damage. We used the “gambling task” to measure decision-making performance and electrodermal activity (skin conductance responses, SCR) as an index of somatic state activation. Allpatients, those with amygdala damage as well as those with VMF damage, were (1) impaired on the gambling task and (2) unable to develop anticipatory SCRs while they pondered risky choices. However, VMF patients were able to generate SCRs when they received a reward or a punishment (play money), whereas amygdala patients failed to do so. In a Pavlovian conditioning experiment the VMF patients acquired a conditioned SCR to visual stimuli paired with an aversive loud sound, whereas amygdala patients failed to do so. The results suggest that amygdala damage is associated with impairment in decision-making and that the roles played by the amygdala and VMF in decision-making are different.
Tinkering with Space: The Organizational Practices of a Nascent Social Venture

The article seeks to further our understanding of the process of organizing nascent social ventures. It builds upon current research on the political and collaborative nature of the social entrepreneurial process, and takes an ANT-inspired processual approach to follow the organizational practices carried by a nascent social venture in its efforts to mobilize stakeholders, bring about collaboration and ultimately secure resources. It draws upon empirical material generated during the first year of a social venture I founded and continue to chair. Findings highlight the adaptive and fluid nature of the organizational practices involved in nascent organizations and indicate that the capacity to continuously adjust the qualities of the eventual venture to the stakes of potential partners is instrumental to start up the venture. The article suggests the notion of tinkering to underscore the fluidity, the ongoing and piecemeal everyday work of such organizing processes. Further, findings highlight the extent to which social ventures, as well as the engaged scholar, are caught in the networks that contribute to reproduce the social problem they aim to change.
Study of Achievement Motivation in Relation to Academic Achievement of Students

The aim of this study was to examine the implications of motivation on individuals. Motivation is the activation of goal-oriented behavior. Motivation is said to be intrinsic or extrinsic. The term is generally used for humans but, theoretically, it can also be used to describe the causes for animal behavior as well. This study refers to human motivation. According to various theories, motivation may be rooted in the basic need to minimize physical pain and maximize pleasure, or it may include specific need such as eating and resting, or a desired object, hobby, goal, state of being, ideal, or it may be attributed to less-apparent reasons such as altruism, selfishness, morality, or avoiding mortality. Conceptually, motivation should not be confused with either volition or optimism. Motivation is related to, but distinct from, emotion. According to the literature, achievement motivation is a subjective and internal psychological drive, enabling individuals to pursue work they perceive to be valuable and prompting them to reach their goals. The literature anchored on Future time perspective theory which stems from Lewin's (1935) psychology and Achievement Motivation theory by Atkinson, 1966. The study revealed that individuals who are intrinsically motivated to learn do so for the pleasure of learning, rather than for external rewards while those who are extrinsically motivated to learn, are motivated to learn for external rewards that learning will bring. Also, students with high academic motivation are more likely to have increased levels of academic achievement and have lower dropout rates. It is generally seen that achievement motivated people evidenced a significantly higher rate of advancement in their company compared to others. It was therefore recommended that parents, teachers and employers should endeavour to promote and encourage academic motivation in students from an early age seeing the importance it plays in forming self-concepts, values and beliefs that students hold about themselves.
Destabilization of microRNAs in human cells by 3′ deadenylation mediated by PARN and CUGBP1

MicroRNA-122 (miR-122), which is expressed at high levels in hepatocytes, is selectively stabilized by 3′-adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2. Here, we report that poly(A)-specific ribonuclease (PARN) is responsible for the deadenylation and destabilization of miR-122. The 3′-oligoadenylated variant of miR-122 was detected in Huh7 cells when PARN was down-regulated. In addition, both the steady-state level and stability of miR-122 were increased in PARN knockdown cells. We also demonstrate that CUG-binding protein 1 (CUGBP1) specifically interacts with miR-122 and other UG-rich miRNAs, and promotes their destabilization. Overexpression of CUGBP1 or PARN in Huh7 cells reduced the steady-state levels of these miRNAs. Because CUGBP1 interacts directly with PARN, we hypothesized that it specifically recruits PARN to miR-122. In fact, CUGBP1 enhanced PARN-mediated deadenylation and degradation of miR-122 in a dose-dependent manner in vitro. These results indicate that the cellular level of miR-122 is determined by the balance between the opposing effects of GLD-2 and PARN/CUGBP1 on the metabolism of its 3′-terminus.
THE CHOICE OF THE FORM OF STRATEGIC ALLIANCES: TRANSACTION COST ECONOMICS AND BEYOND *

This paper focuses on the choice of the governance form of strategic alliances. We survey arguments inspired by the transaction cost economics tradition and other contractual perspectives on the theory of the firm, according to which such choice mainly depends on the transaction cost economizing properties of different organizational forms. We proposes additional considerations based on evolutionary and competence based theories of the firms which emphasize the role of interactive learning in shaping forms’ decisions. In the empirical section, we analyze a sample composed of 140 bilateral contractual (i.e. non equity) agreements and equity joint ventures concluded in the period 1983-’86 by 68 North American, European and Japanese enterprises out of the world largest firms in Information Technology industries. In accordance with the results of previous studies informed by transaction cost economics, the estimates of a logit econometric model provides evidence that firms tend to resort to equity forms to govern complex transactions. On the contrary, for collaborations in the technological sphere they are more likely to use contractual modes. More importantly, the form of alliances proves to be dependent upon the technological capabilities of partner firms, with the probability that a given collaboration be a joint venture decreasing with the degree of overlapping of firms’ patterns of technological specialization.
White-Matter Changes Correlate with Cognitive Functioning in Parkinson’s Disease

Diffusion tensor imaging (DTI) findings from emerging studies of cortical white-matter integrity in Parkinson’s disease (PD) without dementia are inconclusive. When white-matter changes have been found, their relationship to cognitive functioning in PD has not been carefully investigated. To better characterize changes in tissue diffusivity and to understand their functional significance, the present study conducted DTI in 25 PD patients without dementia and 26 controls of similar ages. An automated tract-based DTI method was used. Fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were analyzed. Neuropsychological measures of executive functioning (working memory, verbal fluency, cognitive flexibility, inhibitory control) and visuospatial ability were then correlated with regions of interest that showed abnormal diffusivity in the PD group. We found widespread reductions in FA and increases in MD in the PD group relative to controls. These changes were predominantly related to an increase in RD. Increased AD in the PD group was limited to specific frontal tracks of the right hemisphere, possibly signifying more significant tissue changes. Motor symptom severity did not correlate with FA. However, different measures of executive functioning and visuospatial ability correlated with FA in different segments of tracts, which contain fiber pathways to cortical regions that are thought to support specific cognitive processes. The findings suggest that abnormal tissue diffusivity may be sensitive to subtle cognitive changes in PD, some of which may be prognostic of future cognitive decline.
A SiGe down-conversion micromixer for wideband-CDMA application

This paper presents a micromixer for WCDMA applications with no external balun requirement. The transconverter cells are applied both to LO and RF port to replace the required baluns for converting the single-ended signal to differential output. Besides providing the function of balun, the transconverter cell also improves the linearity behavior. This benefits the RF input stage especially. This micromixer is realized in 0.35 um SiGe BiCMOS technology. The measured input P1 dB is -12 dBm and IIP3 is 2 dBm. The measured isolations of LO port are all higher than 35 dB. The current consumption of mixer core is about 3.5 mA.
Soft Data and Public Policy: Can Social Media Offer Alternatives to Official Statistics in Urban Policymaking?

In recent years, decision makers have reported difficulties in the use of official statistics in public policy: excessively long publication delays, insufficient coverage of topics of interest, and the top-down process of data creation. The deluge of data available online represents a potential answer to these problems, with social media data in particular as a possible alternative to traditional data. In this article, we propose a definition of “Soft Data” to indicate data that are freely available on the Internet, and that are not controlled by a public administration but rather by public or private actors. The term Soft Data is not intended to replace those of “Big Data” and “Open Data,” but rather to highlight specific properties and research methods required to convert them into information of interest for decision makers. The analysis is based on a case study of Twitter data for urban policymaking carried out for a European research program aimed at enhancing the effectiveness of European cohesion policy. The article explores methodological issues and the possible impact of “Soft Data” on public policy, reporting on semistructured interviews carried out with nine European policymakers.
The impacts of cyberhate

The thesis explores the impacts of being exposed to hate material online, so called cyberhate, using social psychological theories of group identity as a framework to explore victimisation experiences when targeted directly or witnessing others from the same identity group being targeted, known as indirect victimisation. Three papers examine these impacts with two commonly stigmatised groups; Lesbian, Gay, Bisexual and Transgender people (LGB&T) and Muslims. Paper 1 reports the results from two online surveys about the nature of cyberhate experienced by these two groups. Results indicate it is a common and frequent problem occurring over a range of internet platforms and mediums and there are a number of negative emotional reactions and behavioural intentions similar to those reported by Intergroup Emotions Theory after group identity challenges. Paper 2 uses qualitative interviews with victims of cyberhate to gain a detailed understanding of the impacts of being victimised. Participants indicated that there is a level of resilience to being targeted as bad behaviour is expected online, but being exposed to hateful material causes many to take avoidance action, avoiding certain parts of the internet. Paper 3 presents the results of an innovative experimental study exposing members of the stigmatised groups and a control to hate material. Those viewing group specific hate material felt angrier than when just viewing generally unpleasant material. The current research finds that being targeted online has similar negative impacts to offline hate crime, both to those who are targeted directly but also those who are indirectly victimised.
The forgotten stage of forest succession: early-successional ecosystems on forest sites

Early-successional forest ecosystems that develop after stand-replacing or partial disturbances are diverse in species, processes, and structure. Post-disturbance ecosystems are also often rich in biological legacies, including surviving organisms and organically derived structures, such as woody debris. These legacies and post-disturbance plant communities provide resources that attract and sustain high species diversity, including numerous early-successional obligates, such as certain woodpeckers and arthropods. Early succession is the only period when tree canopies do not dominate the forest site, and so this stage can be characterized by high productivity of plant species (including herbs and shrubs), complex food webs, large nutrient fluxes, and high structural and spatial complexity. Different disturbances contrast markedly in terms of biological legacies, and this will influence the resultant physical and biological conditions, thus affecting successional pathways. Management activities, such as post-disturbance logging and dense tree planting, can reduce the richness within and the duration of early-successional ecosystems. Where maintenance of biodiversity is an objective, the importance and value of these natural early-successional ecosystems are underappreciated.
Effects of Binge Pattern Cocaine Administration on Dopamine D1 and D2 Receptors in the Rat Brain: AnIn Vivo Study Using Positron Emission Tomography

The aim of the present study was to determine the effect of “binge” pattern cocaine administration on dopamine D1and D2 receptors in the rat brain. Male Sprague Dawley rats were injected three times at 1 hr intervals with saline or cocaine (15 mg/kg) each day for 2, 7, or 14 d. The in vivobinding of [11C]SCH23390 (dopamine D1receptor antagonist) and [11C]N-methylspiperone (NMSP; dopamine D2 receptor antagonist) in the striatal region was measured by a high-resolution positron emission tomography at 1 and 3.5 hr, respectively, after the last cocaine or saline injection. Acute (2 d) binge cocaine administration did not change the in vivobinding potential of [11C]SCH23390 or the binding of [11C]NMSP in the striatum. After 7 d of binge cocaine administration, a significant decrease in the binding potential of [11C]SCH23390 was observed, whereas no change in the binding of [11C]NMSP was found. After 14 d of binge cocaine administration, the in vivo binding was significantly reduced for both [11C]SCH23390 and [11C]NMSP. Separate saturation experiments indicated that the observed alterations of in vivo binding were attributable mainly to apparent alterations in the affinity and not the number of binding sites. These results suggest that both dopamine D1 and D2 receptors may have altered physiologically available binding sites after binge pattern cocaine administration.
Replication of genetic associations as pseudoreplication due to shared genealogy

The genotypes of individuals in replicate genetic association studies have some level of correlation due to shared descent in the complete pedigree of all living humans. As a result of this genealogical sharing, replicate studies that search for genotype‐phenotype associations using linkage disequilibrium between marker loci and disease‐susceptibility loci can be considered as “pseudoreplicates” rather than true replicates. We examine the size of the pseudoreplication effect in association studies simulated from evolutionary models of the history of a population, evaluating the excess probability that both of a pair of studies detect a disease association compared to the probability expected under the assumption that the two studies are independent. Each of nine combinations of a demographic model and a penetrance model leads to a detectable pseudoreplication effect, suggesting that the degree of support that can be attributed to a replicated genetic association result is less than that which can be attributed to a replicated result in a context of true independence. Genet. Epidemiol. 33:479–487, 2009. © 2009 Wiley‐Liss, Inc.
Mining Recent Frequent Itemsets in Sliding Windows over Data Streams

This paper considers the problem of mining recent frequent itemsets over data streams. As the data grows without limit at a rapid rate, it is hard to track the new changes of frequent itemsets over data streams. We propose an effi- cient one-pass algorithm in sliding windows over data streams with an error bound guarantee. This algorithm does not need to refer to obsolete transactions when
Supporting menu design with radial layouts

One of the ways of decreasing selection times in displayed menus is through the use of radial layouts which shorten distances to the items and increase the item sizes. Previous work on radial menus does not demonstrate that radial layouts are beneficial for menu hierarchies. The paper focuses on this topic. We compare two main characteristics of radial and linear layouts: a) the time it takes to find an item (i.e. visual search time), b) the time it takes to navigate to an item (i.e. pointing time). We use objective and subjective measures, two menu sizes, three menu levels, one linear and three radial layout variations. We also present requirements and the Compact Radial Layout (CRL) design which supports menu hierarchies. We assess its performance for novice and expert users.