Miracle-dz/UniFAR-FTUs huggingface dataset:
Global citizenship, migration and national curriculum: A tale of two nations

ABSTRACT Scotland and South Korea are experiencing novel challenges in educating for and about migrant populations. Through a critical discourse analysis of these nations’ national curricula, we consider the guidance educators are offered in teaching about issues related to migration in increasingly diverse classrooms. Framed by theories of critical global citizenship, our analysis suggests that both curricula use ambiguous approaches to global citizenship education. These curricula acknowledge the presence of migrants without disturbing stable visions of Korean and Scottish national identities. Such approaches are reflective of the challenges of integrating migrants into the civic life of South Korea and Scotland.
D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells

Compelling evidence indicates that protein kinase CK2 plays an important role in many steps of cancer initiation and progression, therefore, the development of effective and cell-permeable inhibitors targeting this kinase has become an important objective for the treatment of a variety of cancer types including glioblastoma. We have recently identified 1,3-dichloro-6-[(E)-((4-methoxyphenyl)imino)methyl]dibenzo(b,d)furan-2,7-diol (D11) as a potent and selective inhibitor of protein kinase CK2. In this study, we have further characterized this compound and demonstrated that it suppresses CK2 kinase activity by mixed type inhibition (KI 7.7 nM, KI′ 42 nM). Incubation of glioblastoma cells with D11 induces cell death and upon hypoxia the compound leads to HIF-1α destabilization. The analysis of differential mRNA expression related to human hypoxia signaling pathway revealed that D11-mediated inhibition of CK2 caused strong down-regulation of genes associated with the hypoxia response including ANGPTL4, CA9, IGFBP3, MMP9, SLC2A1 and VEGFA. Taken together, the results reported here support the notion that including D11 in future treatment regimens might turn out to be a promising strategy to target tumor hypoxia to overcome resistance to radio- and chemotherapy.
Preserving Word-Level Emphasis in Speech-to-Speech Translation

Speech-to-speech translation (S2ST) is a technology that translates speech across languages, which can remove barriers in cross-lingual communication. In the conventional S2ST systems, the linguistic meaning of speech was translated, but paralinguistic information conveying other features of the speech such as emotion or emphasis were ignored. In this paper, we propose a method to translate paralinguistic information, specifically focusing on emphasis. The method consists of a series of components that can accurately translate emphasis using all acoustic features of speech. First, linear-regression hidden semi-Markov models (LR-HSMMs) are used to estimate a real-numbered emphasis value for every word in an utterance, resulting in a sequence of values for the utterance. After that the emphasis translation module translates the estimated emphasis sequence into a target language emphasis sequence using a conditional random field model considering the features of emphasis levels, words, and part-of-speech tags. Finally, the speech synthesis module synthesizes emphasized speech with LR-HSMMs, taking into account the translated emphasis sequence and transcription. The results indicate that our translation model can translate emphasis information, correctly emphasizing words in the target language with 91.6% $F$ -measure by objective evaluation. A listening test with human subjects further showed that they could identify the emphasized words with 87.8% $F$ -measure, and that the naturalness of the audio was preserved.
Weak KAM Theory on the Wasserstein Torus with Multidimensional Underlying Space

The study of asymptotic behavior of minimizing trajectories on the Wasserstein space 𝒫(𝕋d) has so far been limited to the case d = 1 as all prior studies heavily relied on the isometric identification of 𝒫(𝕋) with a subset of the Hilbert space L2(0,1). There is no known analogue isometric identification when d > 1. In this article we propose a new approach, intrinsic to the Wasserstein space, which allows us to prove a weak KAM theorem on 𝒫(𝕋d), the space of probability measures on the torus, for any d ≥ 1. This space is analyzed in detail, facilitating the study of the asymptotic behavior/invariant measures associated with minimizing trajectories of a class of Lagrangians of practical importance. © 2014 Wiley Periodicals, Inc.
MERGER SIGNATURES IN THE DYNAMICS OF STAR-FORMING GAS

The recent advent of integral field spectrographs and millimeter interferometers has revealed the internal dynamics of many hundreds of star-forming galaxies. Spatially resolved kinematics have been used to determine the dynamical status of star-forming galaxies with ambiguous morphologies, and constrain the importance of galaxy interactions during the assembly of galaxies. However, measuring the importance of interactions or galaxy merger rates requires knowledge of the systematics in kinematic diagnostics and the visible time with merger indicators. We analyze the dynamics of star-forming gas in a set of binary merger hydrodynamic simulations with stellar mass ratios of 1:1 and 1:4. We find that the evolution of kinematic asymmetries traced by star-forming gas mirrors morphological asymmetries derived from mock optical images, in which both merger indicators show the largest deviation from isolated disks during strong interaction phases. Based on a series of simulations with various initial disk orientations, orbital parameters, gas fractions, and mass ratios, we find that the merger signatures are visible for ∼0.2–0.4 Gyr with kinematic merger indicators but can be approximately twice as long for equal-mass mergers of massive gas-rich disk galaxies designed to be analogs of z ∼ 2–3 submillimeter galaxies. Merger signatures are most apparent after the second passage and before the black holes coalescence, but in some cases they persist up to several hundred Myr after coalescence. About 20%–60% of the simulated galaxies are not identified as mergers during the strong interaction phase, implying that galaxies undergoing violent merging process do not necessarily exhibit highly asymmetric kinematics in their star-forming gas. The lack of identifiable merger signatures in this population can lead to an underestimation of merger abundances in star-forming galaxies, and including them in samples of star-forming disks may bias the measurements of disk properties such as intrinsic velocity dispersion.
Heritability of pulmonary function estimated from pedigree and whole-genome markers

Asthma and chronic obstructive pulmonary disease (COPD) are major worldwide health problems. Pulmonary function testing is a useful diagnostic tool for these diseases, and is known to be influenced by genetic and environmental factors. Previous studies have demonstrated that a substantial proportion of the variation in pulmonary function phenotypes can be explained by familial relationships. The availability of whole-genome single nucleotide polymorphism (SNP) data enables us to further evaluate the extent to which genetic factors account for variation in pulmonary function and to compare pedigree- to SNP-based estimates of heritability. Here, we employ methods developed in the animal breeding field to estimate the heritability of forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and the ratio of these two measures (FEV1/FVC) among subjects in the Framingham Heart Study dataset. We compare heritability estimates based on pedigree-based relationships to those based on genome-wide SNPs. We find that, in a family-based study, estimates of heritability using SNP data are nearly identical to estimates based on pedigree information, and range from 0.50 for FEV1 to 0.66 for FEV1/FVC. Therefore, we conclude that genetic factors account for a sizable proportion of inter-individual differences in pulmonary function, and that estimates of heritability based on SNP data are nearly identical to estimates based on pedigree data. Finally, our findings suggest a higher heritability for FEV1/FVC compared to either FEV1 or FVC.
Heterogeneity in the Energy Cost of Posture Maintenance during Standing Relative to Sitting: Phenotyping According to Magnitude and Time-Course

Background Reducing sitting-time may decrease risk of disease and increase life-span. In the search for approaches to reduce sitting-time, research often compares sitting to standing and ambulation, but the energetic cost of standing alone versus sitting is equivocal, with large variation in reported mean values (0% to >20% increase in energy expenditure (EE) during standing). Objective To determine the magnitude and time-course of changes in EE and respiratory quotient (RQ) during steady-state standing versus sitting. Design Min-by-min monitoring using a posture-adapted ventilated-hood indirect calorimetry system was conducted in 22 young adults with normal BMI during 10 min of steady-state standing versus sitting comfortably. Results This study reveals three distinct phenotypes based on the magnitude and time-course of the EE response to steady-state standing. One-third of participants (8/22) showed little or no change in EE during standing relative to sitting (ΔEE <5%; below first quartile). Of the 14 responders (ΔEE 7–21%), 4 showed sustained, elevated EE during standing, while 10 decreased their EE to baseline sitting values during the second half of the standing period. These EE phenotypes were systematically mirrored by alterations in RQ (a proxy of substrate oxidation), with ΔEE inversely correlated with ΔRQ (r = 0.6–0.8, p<0.01). Conclusion This study reveals different phenotypes pertaining to both energy cost and fuel utilization during standing, raising questions regarding standing as a strategy to increase EE and thermogenesis for weight control, and opening new avenues of research towards understanding the metabolic and psychomotor basis of variability in the energetics of standing and posture maintenance.
Nonlinear Discrete-Time Control Approaches for Underactuated Manipulators

In this paper, we propose two nonlinear discretetime control approaches for underactuated manipulators operating in the horizontal plane which are equipped with passive joints. The first control approach is based on an extended linearization. It can be applied to different kinds of underactuated systems such as a cart-pole system or a highly underactuated manipulator. A manipulator is called a highly underactuated manipulator if it has no braking mechanisms and more passive than active joints. However, the control approach mentioned above performs well only if the errors are sufficiently small. Therefore, a discrete-time feedback controller based on nonlinear online optimization is proposed also to counteract large trajectory deviations. In order to reduce the computation time, we present an initialization strategy of the nonlinear online optimization considering the relation between both controllers. Experimental results of both controller are reported to demonstrate advantages and drawbacks.
Views and Attitudes of Patients in Mental Facilities Regarding Smoking

Introduction: Smoking rates amongst people with a mental health disorder are significantly higher than in the general population and there is growing evidence to show a strong association between smoking and mental health disorders. The aim of the present study was to investigate views and attitudes of mental patients regarding smoking. Material and Methods: The sample is composed of 356 patients treated in the Attica Psychiatric Hospital (a.k.a. “Dafni”) as well as in other Units affiliated with the Hospital. The ‘Smoking in psychiatric hospitals-a survey of patients’ views’ questionnaire was used in the form of semi-structured interviews. The PASW 18 (SPSS Inc.) package was used for the statistical analysis and statistical significance was set to p= 0.05. Results: Overall, 40% of the participants were in-patients, the rest being treated in other settings, the average length of hospital stay was 4.4 years, and the most common diagnosis (61.5.%) was schizophrenia (F20, according to ICD-10), while almost all of the participants (97.5%) were smokers. Most patients (58.8%) said they had had a hard time trying to quit smoking although they had sufficient information and encouragement (≈90%); they also reported that watching the staff smoking did not affect them inasmuch as watching other patients smoking (41 % vs 54.8%). 75.5% of the patients felt that they had no particular difficulty to quit smoking. Men smoked significantly more cigarettes per day compared to females (36.70 vs 30.82, p=0.002). There were no significant differences among males and females regarding previous attempts to quit smoking. Information gathered from such studies should be taken into account when designing systematic smoking management plans in mental institutions. Conclusion: Although almost all mental patients smoke, they seem to be receptive to quitting smoking, since two thirds of them have already tried to quit, but one-third of the patients find smoking a little or not at all dangerous.
Funciones sociales de los Youtubers y su influencia en la preadolescencia

This study focuses on the relationship between preadolescents and youtubers, with the objective of observing how tweens integrate youtubers as referents of a teen digital culture. From a socio-psychological and communicological perspective, a mixed methodological design was applied to carry out the audience study, which was divided into two parts: a quantitative analysis of the audience via a survey administered to 1,406 eleven-twelve year old students of Catalan Secondary Schools, and a qualitative analysis of the preadolescence audience using three focus groups. The quantitative data was analysed with SPSS and the qualitative data with the help of the Atlas.ti software. The results demonstrate that tweens consider youtubers as referents for entertainment and for closeness to a teen digital culture, but not really as a role models or bearers of values as influencers. Also, preadolescents show some dimensions of Media Literacy, since they recognise youtubers’ commercial strategies and their role as actors and professionals. The study notes gender bias in some aspects, and is an introduction to observation of the social functions of youtubers amongst teenagers, individuals who are in the process of constructing their identity and on the point of becoming young adults.
LASSO, Iterative Feature Selection and the Correlation Selector: Oracle inequalities and numerical performances

We propose a general family of algorithms for regression estimation with quadratic loss. Our algorithms are able to select relevant functions into a large dictionary. We prove that a lot of algorithms that have already been studied for this task (LASSO and Group LASSO, Dantzig selector, Iterative Feature Selection, among others) belong to our family, and exhibit another particular member of this family that we call Correlation Selector in this paper. Using general properties of our family of algorithm we prove oracle inequalities for IFS, for the LASSO and for the Correlation Selector, and compare numerical performances of these estimators on a toy example.
Production of Monomeric Aromatic Compounds from Oil Palm Empty Fruit Bunch Fiber Lignin by Chemical and Enzymatic Methods

In this study, oil palm empty fruit bunch (OPEFBF) was pretreated with alkali, and lignin was extracted for further degradation into lower molecular weight phenolic compounds using enzymes and chemical means. Efficiency of monomeric aromatic compounds production from OPEFBF lignin via chemical (nitrobenzene versus oxygen) and enzymatic [cutinase versus manganese peroxidase (MnP)] approaches was investigated. The effects of sodium hydroxide concentration (2, 5, and 10% wt.) and reaction time (30, 90, and 180 minutes) on the yield of aromatic compounds were studied. The results obtained indicated that nitrobenzene oxidation produced the highest yield (333.17 ± 49.44 ppm hydroxybenzoic acid, 5.67 ± 0.25 ppm p-hydroxybenzaldehyde, 25.57 ± 1.64 ppm vanillic acid, 168.68 ± 23.23 ppm vanillin, 75.44 ± 6.71 ppm syringic acid, 815.26 ± 41.77 ppm syringaldehyde, 15.21 ± 2.19 ppm p-coumaric acid, and 44.75 ± 3.40 ppm ferulic acid), among the tested methods. High sodium hydroxide concentration (10% wt.) was needed to promote efficient nitrobenzene oxidation. However, less severe oxidation condition was preferred to preserve the hydroxycinnamic acids (p-coumaric acid and ferulic acid). Cutinase-catalyzed hydrolysis was found to be more efficient than MnP-catalyzed oxidation in the production of aromatic compounds. By hydrolyzed 8% wt. of lignin with 0.625 mL cutinase g−1 lignin at pH 8 and 55°C for 24 hours, about 642.83 ± 14.45 ppm hydroxybenzoic acid, 70.19 ± 3.31 ppm syringaldehyde, 22.80 ± 1.04 ppm vanillin, 27.06 ± 1.20 ppm p-coumaric acid, and 50.19 ± 2.23 ppm ferulic acid were produced.
Heterogeneity and Cooperation in Privileged Groups: The Role of Capability and Valuation on Public Goods Provision

We experimentally investigate cooperation in privileged groups which according to Olson (1965) are groups in which at least one member has an incentive to supply a positive amount of the public good. More specifically, we analyze group member heterogeneity with respect to two dimensions: capability and valuation. Our results reveal that with and without punishment opportunities, heterogeneity crucially affects cooperation and coordination within groups. Compared to non-privileged groups, asymmetric valuations for the public good have negative effects, and asymmetric capabilities in providing the public good have positive effects on voluntary contributions. The main reason for these results are the different externalities contributions have on the other group members’ payoffs affecting individuals’ willingness to cooperate. Hence, whether heterogeneity facilitates or impedes collective action, and whether privileged groups are as privileged as they initially seem is subject to the nature of their asymmetry.
Exchange Rate Determination from Monetary Fundamentals: an Aggregation Theoretic Approach

We incorporate aggregation and index number theory into monetary models of exchange rate determination in a manner that is internally consistent with money market equilibrium. Divisia monetary aggregates and user-cost concepts are used for money supply and opportunity-cost variables in the monetary models. We estimate a flexible price monetary model, a sticky price monetary model, and the Hooper and Morton (1982) model for the US dollar/UK pound exchange rate. We compare forecast results using mean square error, direction of change, and Diebold-Mariano statistics. We find that models with Divisia indexes are better than the random walk assumption in explaining the exchange rate fluctuations. Our results are consistent with the relevant theory and the 'Barnett critique. '
Relating trophic resources to community structure: a predictive index of food availability

The abundance and the distribution of trophic resources available for consumers influence the productivity and the diversity of natural communities. Nevertheless, assessment of the actual abundance of food items available for individual trophic groups has been constrained by differences in methods and metrics used by various authors. Here we develop an index of food abundance, the framework of which can be adapted for different ecosystems. The relative available food index (RAFI) is computed by considering standard resource conditions of a habitat and the influence of various generalized anthropogenic and natural factors. RAFI was developed using published literature on food abundance and validated by comparison of predictions versus observed trophic resources across various marine sites. RAFI tables here proposed can be applied to a range of marine ecosystems for predictions of the potential abundance of food available for each trophic group, hence permitting exploration of ecological theories by focusing on the deviation from the observed to the expected.
Rumination and affective outcomes in women diagnosed with breast cancer

xiv Abstract Breast cancer entails a series of physical, psychosocial and existential challenges that extend into the survivorship period through late side effects from treatment and the potential for disease recurrence. Consequently, higher levels of depressive and anxious symptoms are experienced along the disease trajectory, although positive change, termed post-traumatic growth, can coexist. Perseverative thinking, specifically rumination, has been linked to the development and maintenance of depression and anxiety in clinically-well populations as well as to post-traumaticBreast cancer entails a series of physical, psychosocial and existential challenges that extend into the survivorship period through late side effects from treatment and the potential for disease recurrence. Consequently, higher levels of depressive and anxious symptoms are experienced along the disease trajectory, although positive change, termed post-traumatic growth, can coexist. Perseverative thinking, specifically rumination, has been linked to the development and maintenance of depression and anxiety in clinically-well populations as well as to post-traumatic growth in the cancer context. With limited research into the pathways by which rumination might exert this dual influence, the overall aim was to increase understanding of how subcomponents of rumination are differentially related to positive and negative psychological outcomes in women diagnosed with breast cancer. Given the complexity of the rumination construct, the absence of a specific measure for the context of illness required the development of the Multidimensional Rumination in Illness Scale (MRIS) as an initial step to achieving this aim. Studies 1 and 2 addressed the development, pilot testing, refinement and validation of the MRIS, with solid psychometric properties being demonstrated. A cross-sectional study of individuals with breast cancer (Study 3) found that brooding rumination was associated with depressive and anxious symptoms whereas both instrumental and intrusive rumination were associated with post-traumatic growth. As timing of rumination can be significant, the longitudinal approach in Study 4 revealed more distinctly how patterns of rumination differentially affect psychological outcomes along the illness trajectory. These findings provide a basis for the enhancement of psychological interventions to minimise distress and optimise post-traumatic growth. While cognitive-behavioural therapy (CBT) approaches have been successful in managing distress, CBT does not specifically address rumination, placing importance on the evaluation of the effectiveness of newer CBT modalities, such as Mindfulness-Based Cognitive Therapy, that target rumination through the addition of disclosure techniques and mindfulness meditation.
#freethenipple – digital activism and embodiment in the contemporary feminist movement

ABSTRACT Contemporary, or so-called fourth-wave feminism has heralded an era of online activism which celebrates the potential of this space to reconfigure and reorder gender relations. In this paper we explore an example of an online campaign, #freethenipple, which attempts to disrupt and destabilise a highly sexualised patriarchal breast ideal. We examine both the mechanisms of (re)inscription that feminist activists are using in the campaign and the readings and interpretations of the campaign. We find subtle slippages between these intentions and interpretations. In closing we question the ability of the campaign to revoke dominant patriarchal inscriptions of female bodies, and raise questions about the efficacy of the online environment in effecting real world change.