Miracle-dz/UniFAR-FTUs huggingface dataset:
Wearable Monitoring for Mood Recognition in Bipolar Disorder Based on History-Dependent Long-Term Heart Rate Variability Analysis

Current clinical practice in diagnosing patients affected by psychiatric disorders such as bipolar disorder is based only on verbal interviews and scores from specific questionnaires, and no reliable and objective psycho-physiological markers are taken into account. In this paper, we propose to use a wearable system based on a comfortable t-shirt with integrated fabric electrodes and sensors able to acquire electrocardiogram, respirogram, and body posture information in order to detect a pattern of objective physiological parameters to support diagnosis. Moreover, we implemented a novel ad hoc methodology of advanced biosignal processing able to effectively recognize four possible clinical mood states in bipolar patients (i.e., depression, mixed state, hypomania, and euthymia) continuously monitored up to 18 h, using heart rate variability information exclusively. Mood assessment is intended as an intrasubject evaluation in which the patient's states are modeled as a Markov chain, i.e., in the time domain, each mood state refers to the previous one. As validation, eight bipolar patients were monitored collecting and analyzing more than 400 h of autonomic and cardiovascular activity. Experimental results demonstrate that our novel concept of personalized and pervasive monitoring constitutes a viable and robust clinical decision support system for bipolar disorders recognizing mood states with a total classification accuracy up to 95.81%.
Parenting Style and Dimensions Questionnaire: A Review of Reliability and Validity

Increasing interest in measuring parenting styles, especially with the Parenting Style and Dimensions Questionnaire, has emerged in the last 17 years. However, a critical review of studies using this instrument to assess parenting styles has not been done. The present article proposes an extensive review of studies that applied the instrument, focusing in particular on the different uses of the scale, its psychometric properties, and its association with other constructs. A discussion about the applicability, measurement reliability and validity of the instrument is provided.
Does Spatial Disaggregation Matter in Job Creation and Destruction Flows

The paper investigates the changes in job creation and destruction flows considering a very disaggregate level of analysis. If institutional setup plays a more important role compared to other factors, than at lower levels of aggregation we should observe that job flows regularities are in line with national ones. We explore the issue using a unique database on the population of firms in Trentino (a North-Eastern Province of Italy) from 1991 to 2001. We find that: (a) job flows show a ”fractal” nature, i.e. many regularities appear to be scale invariant (magnitude of flows and their persistence). In particular job flows magnitude is in line with the average values for Italy; (b) there are some qualifications to ”fractality”: entrant firms’ contribution to job creation process is lower than the corresponding contribution at national level, whereas the job destruction share accounted for by exit firms is around 30%, in line with stylized facts; (c) size and age shape the job flows; (d) shifts of jobs between macro sectors are rare.
Effect of PCI on quality of life in patients with stable coronary disease.

BACKGROUND It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS At baseline, 22% of the patients were free of angina. At 3 months, 53% of the patients in the PCI group and 42% in the medical-therapy group were angina-free (P<0.001). Baseline mean (+/-SD) Seattle Angina Questionnaire scores (which range from 0 to 100, with higher scores indicating better health status) were 66+/-25 for physical limitations, 54+/-32 for angina stability, 69+/-26 for angina frequency, 87+/-16 for treatment satisfaction, and 51+/-25 for quality of life. By 3 months, these scores had increased in the PCI group, as compared with the medical-therapy group, to 76+/-24 versus 72+/-23 for physical limitation (P=0.004), 77+/-28 versus 73+/-27 for angina stability (P=0.002), 85+/-22 versus 80+/-23 for angina frequency (P<0.001), 92+/-12 versus 90+/-14 for treatment satisfaction (P<0.001), and 73+/-22 versus 68+/-23 for quality of life (P<0.001). In general, patients had an incremental benefit from PCI for 6 to 24 months; patients with more severe angina had a greater benefit from PCI. Similar incremental benefits from PCI were seen in some but not all RAND-36 domains. By 36 months, there was no significant difference in health status between the treatment groups. CONCLUSIONS Among patients with stable angina, both those treated with PCI and those treated with optimal medical therapy alone had marked improvements in health status during follow-up. The PCI group had small, but significant, incremental benefits that disappeared by 36 months. (ClinicalTrials.gov number, NCT00007657.)
Lesbian Parenting: Insiders' Voices

Lesbian parenting has entered the public arena over recent years via debates regarding access to fertility services and adoption, legal recognition of same-sex parents and children's rights (McNair, 2002). Research in the area has been published for over 20 years, with an increasing shift towards delineating diversity rather than proving the legitimacy of these families. The ANZJFT - the major mouthpiece for Australian family therapists - has made curiously little contribution to the literature on lesbian parenting. The lack of discussion leaves trainees and family therapists largely ignorant about the lived experience of lesbian family life. This paper goes some way to filling this gap. We present data gathered from 151 Australian lesbian parents who answered questions about their own and their families' perceived strengths. Despite the constraints and challenges of living within a heteronormative and homophobic society and dealing with discrimination and legal, political and social non-legitimation, this group of lesbian parents expressed great pride in raising well adjusted and happy children. They also described their families as thoughtfully planned, proud, accepting and celebratory of diversity and difference, flexible in gender roles, and as having interesting, supportive, extended kinship networks that included a wide range of positive role models for their children. (author abstract)
BEHL WORKING PAPER SERIES WP 2014-01 Antisemitism Affects Households ' Investments

We propose historical anti-Jewish sentiment as a proxy for distrust in financial markets. Households in German counties where Jews were persecuted the most as far back as in the Middle Ages are less likely to invest in stocks today. A one-standard-deviation increase in historical anti-Jewish violence leads to a 7.5% to 12% drop in the average stock market participation. For identification, we exploit the forced migrations of Ashkenazi Jews out of the Rhine Valley after the 11th century. The distance of a county from the Rhine Valley instruments for the existence of a Jewish community during the Black Death (1349) and hence the early emergence of anti-Jewish sentiment. Results are similar when we use the votes for the Nazi party as a proxy for anti-Jewish sentiment. The magnitude of the effect does not change from 1984 until 2011 nor across cohorts. Anti-Jewish sentiment does not capture generalized trust: its effect on stockholdings is similar across counties and households with dfferent levels of education.
Right Ventricular Longitudinal Strain Measures Independently Predict Chronic Heart Failure Mortality

The assessment of right ventricular (RV) function still remains a challenge. Two‐dimensional (2D) speckle tracking has recently been proposed to evaluate right ventricular function by analyzing myocardial deformation. The aim of this study was to evaluate the role of 2D systolic strain measures of RV in predicting mortality in patients with chronic heart failure (HF). We enrolled 332 outpatients in a stable clinical condition and in conventional therapy. A right ventricular–focused four‐chamber view was analyzed by 2D speckle tracking to evaluate the global longitudinal strain of RV (RV‐GLS) and the strain of RV free wall (RV‐fwLS). During a mean follow‐up of 36 ± 26 months, 64 patients died. Both RV‐GLS and RV‐fwLS were associated with all‐cause mortality in univariate (HR: 1.16; 95% CI: 1.10–1.23; P < 0.001; C‐index: 0.72; and HR: 1.10; 95% CI: 1.06–1.15; P < 0.001; C‐index: 0.68, respectively) as well as multivariate analysis (HR: 1.13; 95% CI: 1.05–1.21; P:0.001; C‐index: 0.85; and HR: 1.07; 95% CI: 1.02–1.12; P:0.004; C‐index: 0.84, respectively). In conclusion, our findings demonstrate the role of RV 2D strain measures to independently predict mortality. These data highlight the clinical usefulness of this echocardiographic approach in the daily management of HF outpatients.
A Comparison of Three Different Rest Intervals Between Multiple Squat Bouts

The effects of 3 different rest intervals on resistance training performance were examined. Fifteen resistance trained men completed 4 testing sessions. Session 1 was used to establish a 10 repetition maximum (RM). During the next 3 sessions the subjects performed 4 sets of squats to voluntary exhaustion with 85% of their 10-RM. Recovery time among sets was randomly assigned from: achieving a postexercise heart rate of 60% age-predicted maximum (Post-HR); a timed 3-min interval (3-min); and a 1:3 work:rest ratio (1:3 W/R). No significant differences were observed in repetitions to exhaustion, blood lactate concentrations, or RPE among the 3 recovery conditions. Post-HR, 3-min, and 1:3 W/R recovery conditions were equally effective methods of recovery during the 4 sets of parallel squats to exhaustion.
Student justice perceptions following assignment feedback

In higher education, students are exposed to regular feedback about their performance, and a prominent aspect of students’ attention to feedback concerns the extent to which grades are consistent with what a student has expected to receive. Any discrepancies that arise can result in negative justice perceptions, which research has shown are associated with negative cognitive, emotional and behavioral consequences. However the extent of, and consequences of, these negative justice perceptions within the learning process have gone largely unexplored. This study investigates the relationship between expectation/performance discrepancies, justice perceptions, student satisfaction and self‐efficacy. In particular, we found an interaction between the grade received and negative justice perceptions; poor performers with negative justice perceptions were more likely to have lower subsequent self‐efficacy and satisfaction than those who did not have injustice perceptions. However, self‐efficacy rose for those who had negative justice perceptions if they also received moderate to high performance feedback. The results reflect the complexity of cognitive and behavioral responses to performance feedback. Implications for grading and recommendations for reducing injustice perceptions are discussed.
Observations on a Service Review: Time to Move On?

This paper considers the functioning of one educational psychology service (EPS) at a particularly troubled point in its existence. A focus on a review of the service and resultant pilot of a new model of service delivery will lead to consideration of how and why this process took place. Implications for the service in particular and the profession in general will be explored, and it will be argued that what was a potentially undermining and stressful period, may have been an opportunity to re‐examine what educational psychology has to offer.
Children and marital stability

This research investigated the relationship between early childbearing and marital instability. A moderate U-shaped relationship between the number of children a woman had at the beginning of an interval and the likelihood that she would experience dissolution during the interval was found. Women with large families and those with no children were the most likely to experience disruption. The lowest dissolution rates were found for those with moderate numbers of children.
Notes on enriched categories with colimits of some class (completed version)

The paper is in essence a survey of categories having $\phi$-weighted colimits for all the weights $\phi$ in some class $\Phi$. We introduce the class $\Phi^+$ of {\em $\Phi$-flat} weights which are those $\psi$ for which $\psi$-colimits commute in the base $\V$ with limits having weights in $\Phi$; and the class $\Phi^-$ of {\em $\Phi$-atomic} weights, which are those $\psi$ for which $\psi$-limits commute in the base $\V$ with colimits having weights in $\Phi$. We show that both these classes are {\em saturated} (that is, what was called {\em closed} in the terminology of \cite{AK88}). We prove that for the class $\p$ of {\em all} weights, the classes $\p^+$ and $\p^-$ both coincide with the class $\Q$ of {\em absolute} weights. For any class $\Phi$ and any category $\A$, we have the free $\Phi$-cocompletion $\Phi(\A)$ of $\A$; and we recognize $\Q(\A)$ as the Cauchy-completion of $\A$. We study the equivalence between ${(\Q(\A^{op}))}^{op}$ and $\Q(\A)$, which we exhibit as the restriction of the Isbell adjunction between ${[\A,\V]}^{op}$ and $[\A^{op},\V]$ when $\A$ is small; and we give a new Morita theorem for any class $\Phi$ containing $\Q$. We end with the study of $\Phi$-continuous weights and their relation to the $\Phi$-flat weights.
Risk Preference Predictions and Gender Stereotypes

This article reports a study examining biases in predicting the risk preferences of other people. Results showed that both women and men overestimated males' risk preferences, but accurately predicted women's risk preferences. The same effect was observed for options with positive outcomes and for options with negative outcomes. Results of our research suggest that participants' predictions were influenced by knowledge about risk preferences incorporated in gender stereotypes and by their own feelings. People are especially prone to make biased predictions when they compare themselves with other men. Previous findings that people are less risk averse for losses than for gains were successfully replicated. Practical and theoretical implications of the findings are discussed.
C677T variant form at the MTHFR gene and CL/P: a risk factor for mothers?

Maternal folic acid supplementation in early pregnancy has been suggested to play a role in the prevention of nonsyndromic orofacial cleft, i.e., cleft lip with or without cleft palate (CL/P). Moreover, some authors demonstrated association of the C-->T mutation (C677T), converting an alanine to a valine residue in 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, with other congenital anomalies such as neural tube defects (NTDs). Because of MTHFR's involvement in the metabolism of folate, we investigated 64 CL/P patients and their parents for C677T MTHFR mutation. No linkage disequilibrium was found using the transmission disequilibrium test (TDT). However, a significantly higher mutation frequency was detected in mothers of CL/P patients compared to controls. The odds ratios calculated for mothers having CT or TT genotype, compared to the normal CC genotype, were 2.75 (95% confidence interval 1.30-5.57) and 2.51 (1.00-6.14), respectively. These results support the involvement of the folate pathway in the etiology of CL/P, and indicate an effect of the maternal genotype, rather than influence of the embryo's genotype.
Latinos in a College Outreach Program: Application, Selection, and Participation

College outreach programs provide key access along the academic pipeline, yet little is known about how students access or engage with these programs. Data were collected as part of a university-community partnership. Analyses of student applications revealed that most had aspirations for college-based careers. They saw institutions, family members, and school personnel as resources to achieve their goals, and institutions and relationships as obstacles. Program selection reflected students' gender and criteria among school staff about who would benefit the most from the program. Program participation was motivated by both their social and academic goals and whether they saw themselves as a resource.
Grades, Coursework, and Student Characteristics in High School Economics

The authors use U.S. public and private high school transcripts to analyze grade distribution patterns in economics courses across student and school characteristics, and compare these grades to those earned in other selected high school courses. Results are reported for the 53 percent of 2009 high school graduates who took a basic economics course and the additional 5 percent who took a college-level course in high school. Basic economics grades were relatively high but within range compared to grades earned in other social studies courses, and higher than the grades in mathematics and science courses. College-level economics grades were lower on average than those earned in college-level social studies courses, comparable to grades in college-level mathematics courses, and lower than grades in college-level science courses.
Appropriate Uses of Computer‐Mediated Communication Systems for Education; Conferencing ‘R‐PLACES’

What can be done with computer‐mediated communications (CMC) that will be really valuable educationally in our complex, highly interdependent, uncertain world? In order to answer this question a brief categorization of five generations of CMC is given, followed by a discussion of some acute educational needs which may best be met by CMC in the form of ‘R‐PLACES’ (Reciprocative participatory ‐ Performance Learning Action, Cybersystemic Emulation Spaces) for fostering culturally and ecologically symbiotic learning. Criteria for appropriate Reciprocity‐PLACES design and development based upon recent experience and research are given.
Untangling word webs: graph theory and the notion of density in second language word association networks

This article examines the implications of the metaphor of the ‘vocabulary network’. It takes a formal approach to the exploration of this metaphor by applying the principles of Graph Theory to word association data in order to compare the relative densities of first language (L1) and second language (L2) lexical networks. Earlier graph theoretical research into L2 word associations is reviewed and methodological flaws in this work discussed. It describes the development of a new elicitation tool which is able to provide a means of quantifying lexical density levels. Levels of linkage in the L1 and L2 lexical networks are shown to be higher than previously assumed in the literature. It is argued that it will be helpful to develop a more complex interpretation of the notion of lexical density.
Identity repertoires among Arabs in Israel

This study investigates the structure and components of the Arab identity repertoire in Israel. We analyse the relative salience of each component and the structural relations among the components. In addition we interpret the meanings associated with each component of the Arab identity repertoire in Israel. Our study differs from traditional investigations of Arab identities in Israel in considering identity as a multi‐dimensional phenomenon, and in interpreting the meanings that the respondents assign to the relevant identities. Empirically we find that most Arabs in Israel feel strongly attached to at least three identities, none of them dominating the others. The correlations among the identities are low, meaning that they are only marginally affected by the feasibility of alternative identities and more by the type of practices performed in each respective milieu. In this respect it is interesting to see that the Palestinian identity is not associated with citizenship beyond national pride, while the Israeli identity is expected to supply them with a sense of citizenship. Our finding that different groups constitute for themselves different relations among the components of the identity repertoire suggests that our multi‐dimensional model supplies a better explanation for the structure of Arab repertoires of identities.
Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing’s sarcoma

Summary The most prevalent forms of bone cancer are osteosarcoma, chondrosarcoma, and Ewing’s sarcoma. Although chemotherapy and radiotherapy have replaced traditional surgical treatments, survival rates have undergone only marginal improvements. Current knowledge of the molecular pathways involved in each type of cancer has led to better approaches in cancer treatment. A number of cell signaling molecules are involved in tumorigenesis, and specific targets have been identified based on these signal transducers. This review highlights some of the important cellular pathways and potential therapeutic targets, tumor site-specific irradiation techniques, and novel drug delivery systems used to administer these drugs.
Phosphorylation at the Nuclear Localization Signal of Ca2+/Calmodulin-dependent Protein Kinase II Blocks Its Nuclear Targeting*

Translocation of protein kinases with broad substrate specificities between different subcellular compartments by activation of signaling pathways is an established mechanism to direct the activity of these enzymes toward particular substrates. Recently, we identified two isoforms of Ca2+/calmodulin-dependent protein kinase II (CaM kinase II), which are targeted to the nucleus by an alternatively spliced nuclear localization signal (NLS). Here we report that cotransfection with constitutively active mutants of CaM kinase I or CaM kinase IV specifically blocks nuclear targeting of CaM kinase II as a result of phosphorylation of a Ser immediately adjacent to the NLS of CaM kinase II. Both CaM kinase I and CaM kinase IV are able to phosphorylate this Ser residue in vitro, and mutagenesis studies suggest that this phosphorylation is both necessary and sufficient to block nuclear targeting. Furthermore, we provide experimental evidence that introduction of a negatively charged residue at this phosphorylation site reduces binding of the kinase to an NLS receptor in vitro, thus providing a mechanism that may explain the blockade of nuclear targeting that we have observedin situ.
Critical place as a fluid margin in post-critical environmental education

Positive claims about place pedagogy in education are problematized through this small-scale interpretive study of internationally mobile students’ experiences of outdoor environmental education. Of specific interest in this empirical study of learners’ pedagogically constructed experiences of place are the fluid subjectivities, cultural dispositions, environmental consciences, and ecological assumptions they already bring ‘globally’ to the ‘place’ of the educational intervention, and the hybrid ‘splaces’ we conclude they then temporarily embody – at least, during and after the experience. The study empirically advances an ongoing need for post-critical inquiry in environmental research by incorporating a range of theoretical and conceptual resources that work the boundaries, ‘margins’, and tensions that lie somewhere ‘in-between’ the spatially projected place/local and planet/global discourses.