Miracle-dz/UniFAR-FTUs huggingface dataset:
Genetic Factors in Athetoid Cerebral Palsy

Within the cerebral palsy syndromes, athetosis is most commonly causally associated with serious perinatal complications. Genetic factors are thought to play a lesser role, although the risk of recurrence in siblings has been suggested to be as high as 10%. We have conducted a clinical study of 22 subjects with a diagnosis of athetoid cerebral palsy and a review of the literature aiming to identify instances of familial recurrence of athetoid cerebral palsy. The birth history, family history, and previous investigations of subjects with athetoid cerebral palsy were studied and subjects were clinically examined for evidence of an underlying genetic etiology. Factors suggesting a genetic cause were specifically sought, such as advanced paternal age, progression of symptoms, and associated congenital abnormalities. No subjects in the study group had similarly affected relatives, and additional features suggesting a genetic cause were not observed. A literature search identified 16 instances of familial recurrence of athetoid cerebral palsy. Familial cases were typically associated with significant spasticity, microcephaly, intellectual disability, seizures, and a lack of history of birth asphyxia, and most could be explained by either autosomal-recessive or X-linked-recessive inheritance. The genetic contribution to athetoid cerebral palsy is small, with an overall risk of recurrence in siblings of about 1%. This risk is lower than previously suggested in the literature. (J Child Neurol 2001;16:793—797).
Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease

Abstract Dry eye disease (DED) affects >10% of the population worldwide, and it provokes an unpleasant sensation of ocular dryness, whose underlying neural mechanisms remain unknown. Removal of the main lachrymal gland in guinea pigs caused long-term reduction of basal tearing accompanied by changes in the architecture and density of subbasal corneal nerves and epithelial terminals. After 4 weeks, ongoing impulse activity and responses to cooling of corneal cold thermoreceptor endings were enhanced. Menthol (200 &mgr;M) first excited and then inactivated this augmented spontaneous and cold-evoked activity. Comparatively, corneal polymodal nociceptors of tear-deficient eyes remained silent and exhibited only a mild sensitization to acidic stimulation, whereas mechanonociceptors were not affected. Dryness-induced changes in peripheral cold thermoreceptor responsiveness developed in parallel with a progressive excitability enhancement of corneal cold trigeminal ganglion neurons, primarily due to an increase of sodium currents and a decrease of potassium currents. In corneal polymodal nociceptor neurons, sodium currents were enhanced whereas potassium currents remain unaltered. In healthy humans, exposure of the eye surface to menthol vapors or to cold air currents evoked unpleasant sensations accompanied by increased blinking frequency that we attributed to cold thermoreceptor stimulation. Notably, stimulation with menthol reduced the ongoing background discomfort of patients with DED, conceivably due to use-dependent inactivation of cold thermoreceptors. Together, these data indicate that cold thermoreceptors contribute importantly to the detection and signaling of ocular surface wetness, and develop under chronic eye dryness conditions an injury-evoked neuropathic firing that seems to underlie the unpleasant sensations experienced by patients with DED.
Hand Dominance and Bilateral Asymmetry of the Epicondylar Breadth of the Humerus

For this consideration of bilateral asymmetry of the epicondylar breadth of the distal humerus and its relationship to hand dominance, metric analysis of the humerus was conducted on a living population from Ontario, Canada, and on the late AngloSaxon skeletal population (tenth to eleventh century AD) from Raunds Furnells, Northamptonshire (UK). Examination of trends in adult asymmetry reveals that while certain variables, such as age and sex, can be influential, biomechanical factors appear to be of primary importance in the expression of this trait. This type of study provides insight into how asymmetry is expressed in a modern population as well as providing a means to monitor changes in asymmetry in the past.
Parenting the Gifted: Is This a Job for Superparent?

If I were to say that I had a retarded or physically handicapped child, people would believe me. No one would resent me, and most reactions would be sympathetic. Having a gifted child, however, I know I do better keeping quiet. People wouldn't believe me, and they would resent me. “Another bragging mother” I would be called…
Event triggered control for multi-agent systems with packet dropout

In this paper the discrete event triggered control for multi-agent systems with packet dropout is considered the first time. The scheme is essentially a discrete-time scheme, with no need of monitoring the systems' states continuously. Rather than focusing on the communication topology every instant, the effects the quality of the whole communication having on the system for a long time is considered. A sufficient condition guaranteeing the system to achieve stochastical weighted-average consensus under a certain given event condition is presented. Finally a numerical example is given to illustrate the effectiveness of the theoretical result and some analyses are presented accordingly.
Efeito das modalidades de resposta sobre a estruturação de uma representação social: o exemplo da representação dos estudos

A research relating to the social representation of the studies was carried out in order to explore the potential effect of the answers modalities in a calling into question questionnaire. Two questionnaires varying by the number of response and the presence of a midpoint were proposed to 251 young highschool pupils. The results underline the important impact of the answers modalities on the structures obtained. In one case (4 answers) the representation includes three central elements; in the other (5 answers), it contains only one of them. These results confirm those of former research concerning the impact of the midpoint in the calling into question method by reduction of the number of central elements of the representation. This type of research contributes to thinking about the methods used within the framework of the study of the social representations, but also to feed the epistemological stakes subjacent to these methods.
The Physiological Changes, Growth Performance and Whole Body Composition of Common Carp, Cyprinus carpio Fed on Diet Containing Wood Betony, Stachys lavandulifolia Extract

The Effect of different levels of Wood Betony (WB), Stachys lavandulifolia extract, as complement in feed, on the performance of common carp, Cyprinus carpio was evaluated. The fish (44±0.62 g) was assigned to four treatments, three replicates each. The fish was fed on normal diet with no WB (control) vs. diet containing 2, 4 and 8% of WB extract. Fish were successively fed on the diet, 2% live body weight, three daily for 70 days. The results revealed that final weight, mean weight gain and specific growth rate were significantly improved by increasing WB levels in the diet. The highest growth performance and the lowest feed conversion ratio were recorded for 8% WB treatment. No significant changes were observed in the proximate whole body composition among different groups. Hemoglobin content and hematocrit value increased significantly in the second group in comparison with the others (P< 0.05). The highest serum total protein (5.05±1.4 g dl -1 ) and globulin (2.47±0.3 g dl -1 ) were recorded in the fish fed on the highest dose of WB (8%). Inclusion of 2% of WB in the diet reduced serum triglycerides (317.44±89 mg dl -1 ) and cholesterol (141.51±35 mg dl -1 ) in comparison with control (P< 0.05). It could be concluded that feeding common carp with the diet enriched with WB extract could enhance growth rate, improve some hematological and biochemical characteristics with no adverse effects on body composition.
Throwing Good Money After Bad: The Effect of Sunk Costs on the Decision to Escalate Commitment to an Ongoing Project

Les relations fonctionnelles entre les couts et la decision de poursuivre un investissement dans un projet de recherche et de developpement sont examinees avec 407 etudiants en commerce. Les sujets lisent un scenario dans lequel 10%, 30%, 50%, 70% ou 90% d'un budget de 10 millions de dollars ont ete investis. Un groupe doit indiquer s'il est souhaitable d'investir les fonds restants pour finir le projet. Un second groupe indique s'il investirait volontiers un million de dollars de plus pour poursuivre le projet. Le troisieme groupe evalue si le projet donnera des profits
Effect of real-time feedback during cardiopulmonary resuscitation outside hospital: prospective, cluster-randomised trial

Objective To investigate whether real-time audio and visual feedback during cardiopulmonary resuscitation outside hospital increases the proportion of subjects who achieved prehospital return of spontaneous circulation. Design A cluster-randomised trial. Subjects 1586 people having cardiac arrest outside hospital in whom resuscitation was attempted by emergency medical services (771 procedures without feedback, 815 with feedback). Setting Emergency medical services from three sites within the Resuscitation Outcomes Consortium in the United States and Canada. Intervention Real-time audio and visual feedback on cardiopulmonary resuscitation (CPR) provided by the monitor-defibrillator. Main outcome measure Prehospital return of spontaneous circulation after CPR. Results Baseline patient and emergency medical service characteristics did not differ between groups. Emergency medical services muted the audible feedback in 14% of cases during the period with feedback. Compared with CPR clusters lacking feedback, clusters assigned to feedback were associated with increased proportion of time in which chest compressions were provided (64% v 66%, cluster-adjusted difference 1.9 (95% CI 0.4 to 3.4)), increased compression depth (38 v 40 mm, adjusted difference 1.6 (0.5 to 2.7)), and decreased proportion of compressions with incomplete release (15% v 10%, adjusted difference −3.4 (−5.2 to −1.5)). However, frequency of prehospital return of spontaneous circulation did not differ according to feedback status (45% v 44%, adjusted difference 0.1% (−4.4% to 4.6%)), nor did the presence of a pulse at hospital arrival (32% v 32%, adjusted difference −0.8 (−4.9 to 3.4)), survival to discharge (12% v 11%, adjusted difference −1.5 (−3.9 to 0.9)), or awake at hospital discharge (10% v 10%, adjusted difference −0.2 (−2.5 to 2.1)). Conclusions Real-time visual and audible feedback during CPR altered performance to more closely conform with guidelines. However, these changes in CPR performance were not associated with improvements in return of spontaneous circulation or other clinical outcomes. Trial Registration Clinical Trials NCT00539539
Early adult outcomes of adolescent binge drinking: person- and variable-centered analyses of binge drinking trajectories.

BACKGROUND Many studies of the consequences of binge drinking take a variable-centered approach that may mask developmentally different trajectories. Recent studies have reported qualitatively different binge drinking trajectories in young adulthood. However, analyses of developmental trajectories of binge drinking have not been examined for an important period of drinking development: adolescence. The purpose of this study was to examine young adult outcomes of adolescent binge drinking using an approach that combines person-centered and variable-centered methods. METHODS Data were from the Seattle Social Development Project, an ethnically diverse, gender balanced sample (n = 808) followed prospectively from age 10 to age 21. Semiparametric group-based modeling was used to determine groups of binge drinking trajectories in adolescence. Logistic regression was used to examine how well the trajectory groups predicted young adult outcomes after demographics, childhood measures, and adolescent drug use were considered. RESULTS Four distinct trajectories of binge drinking during adolescence were identified: Early Highs, Increasers, Late Onsetters, and Nonbingers. These trajectories significantly predicted positive and negative outcomes in adulthood after controlling for demographic characteristics, early proxy measures of the outcome, and adolescent drug use. CONCLUSIONS This integrated person- and variable-centered approach provides more information about the effects of specific patterns of binge drinking than studies that employ variable-centered methods alone.
Simulating galactic outflows with kinetic supernova feedback

Feedback from star formation is thought to play a key role in the formation and evolution of galaxies, but its implementation in cosmological simulations is currently hampered by a lack of numerical resolution. We present and test a subgrid recipe to model feedback from massive stars in cosmological smoothed particle hydrodynamics simulations. The energy is distributed in kinetic form among the gas particles surrounding recently formed stars. The impact of the feedback is studied using a suite of high-resolution simulations of isolated disc galaxies embedded in dark haloes with total mass 10 10 and 10 12 h -1 M ⊙ . We focus, in particular, on the effect of pressure forces on wind particles within the disc, which we turn off temporarily in some of our runs to mimic a recipe that has been widely used in the literature. We find that this popular recipe gives dramatically different results because (ram) pressure forces on expanding superbubbles determine both the structure of the disc and the development of large-scale outflows. Pressure forces exerted by expanding superbubbles puff up the disc, giving the dwarf galaxy an irregular morphology and creating a galactic fountain in the massive galaxy. Hydrodynamic drag within the disc results in a strong increase in the effective mass loading of the wind for the dwarf galaxy, but quenches much of the outflow in the case of the high-mass galaxy.
Unshackling evolution: evolving soft robots with multiple materials and a powerful generative encoding

In 1994 Karl Sims showed that computational evolution can produce interesting morphologies that resemble natural organisms. Despite nearly two decades of work since, evolved morphologies are not obviously more complex or natural, and the field seems to have hit a complexity ceiling. One hypothesis for the lack of increased complexity is that most work, including Sims', evolves morphologies composed of rigid elements, such as solid cubes and cylinders, limiting the design space. A second hypothesis is that the encodings of previous work have been overly regular, not allowing complex regularities with variation. Here we test both hypotheses by evolving soft robots with multiple materials and a powerful generative encoding called a compositional pattern-producing network (CPPN). Robots are selected for locomotion speed. We find that CPPNs evolve faster robots than a direct encoding and that the CPPN morphologies appear more natural. We also find that locomotion performance increases as more materials are added, that diversity of form and behavior can be increased with different cost functions without stifling performance, and that organisms can be evolved at different levels of resolution. These findings suggest the ability of generative soft-voxel systems to scale towards evolving a large diversity of complex, natural, multi-material creatures. Our results suggest that future work that combines the evolution of CPPN-encoded soft, multi-material robots with modern diversity-encouraging techniques could finally enable the creation of creatures far more complex and interesting than those produced by Sims nearly twenty years ago.
Perceived coach behaviors and athletes' engagement and disaffection in youth sport: the mediating role of the psychological needs.

Understanding of how coaches influence adolescents' levels of engagement and disaffection in youth sport is important in light of the high attrition in this population. Grounded in self-determination theory, we proposed and tested a mediation model that describes pathways linking perceptions of coach behavior (autonomy supportive versus controlling) to adolescents' engagement and disaffection via psychological need satisfaction and thwarting in youth sport. One-hundred and fifty-three adolescent soccer players (Mage = 13.96 ± 1.41) completed a questionnaire that assessed the study variables. Structural equation modelling supported the hypothesised model. Perceptions of autonomy support positively predicted psychological need satisfaction which, in turn, positively predicted engagement. Perceptions of controlling behaviors positively predicted psychological need thwarting which, in turn, positively predicted disaffection. In addition, a number of cross-over paths emerged. The findings
Elementary School Mathematics Teacher Trainees Metacognitive Awareness Levels: Turkey Case

The aim of this research is to determine the metacognitive awareness levels of elementary mathematics teacher trainees and to investigate whether their awareness differs according to gender and class level. We also investigate the relationship between the metacognitive awareness levels of trainee mathematics teachers and their overall performance course grades. The Metacognitive Awareness Inventory, developed by Schraw and Dennison (1994) and adapted into Turkish by Ak? n, Abac? and tin (2007), was implemented with a total of 153 mathematics teacher trainees. Analysis of the data collected suggests that most of the mathematics teacher trainees have a high level of metacognitive awareness. There was no significant difference between the metacognitive awareness levels of mathematics teacher trainees by gender or by class levels. There was a low level, positive relationship between their metacognitive awareness levels and their overall performance on university course grades.
Evaluation Of Elastic Modulus And Stress Gradient Of PECVD Silicon Nitride Thin Films

This study investigated the techniques for determining the elastic modulus and estimating the stress gradient of plasma-enhanced chemical vapor deposition (PECVD) silicon nitride thin films. The experimentally determined elastic modulus was then used in a finite element beam model to compute the stress distribution inside the thin films using a commercial finite element analysis package. The computed beam displacement caused by a given stress gradient was compared with the displacement experimentally evaluated using optical interference microscopy. This comparison allows the stress gradient of the PECVD silicon nitride membrane introduced by the fabrication process to be evaluated.
Optimized Spoofing and Jamming a Cognitive Radio

We examine the performance of a cognitive radio system in a hostile environment where an intelligent adversary tries to disrupt communications by minimizing the system throughput. We investigate the optimal strategy for spoofing and jamming a cognitive radio network with a Gaussian noise signal over a Rayleigh fading channel. We analyze a cluster-based network of secondary users (SUs). The adversary may attack during the sensing interval to limit access for SUs by transmitting a spoofing signal. By jamming the network during the transmission interval, the adversary may reduce the rate of successful transmission. We present how the adversary can optimally allocate power across subcarriers during sensing and transmission intervals with knowledge of the system, using a simple optimization approach specific to this problem. We determine a worst-case optimal energy allocation for spoofing and jamming, which gives a lower bound to the overall information throughput of SUs under attack.
Evidence‐based practice and evaluation: from insight to impact

With the growing emphasis on accountability and evidence‐based practice, evaluation has become increasingly important in the contexts in which educational psychologists (EPs) practice. This paper describes a Target Monitoring and Evaluation (TME) system, derived from Goal Attainment Scaling (GAS) which was developed to evaluate outcomes of a wide range of interventions that were established as a result of an EP and an assistant EP involvement in two local authorities. Pupils made progress on between 94% and 97% of targets, and outcomes were significantly better than the baseline for both groups. Results are considered in terms of the value and usefulness of TME as an evaluation system and key issues relating to its implementation within EP practice are discussed.
Challenge Point: A Framework for Conceptualizing the Effects of Various Practice Conditions in Motor Learning

The authors describe the effects of practice conditions in motor learning (e.g., contextual interference, knowledge of results) within the constraints of 2 experimental variables: skill level and task difficulty. They use a research framework to conceptualize the interaction of those variables on the basis of concepts from information theory and information processing. The fundamental idea is that motor tasks represent different challenges for performers of different abilities. The authors propose that learning is related to the information arising from performance, which should be optimized along functions relating the difficulty of the task to the skill level of the performer. Specific testable hypotheses arising from the framework are also described.
Understanding Psychological Preparation for Sport: Theory and Practice of Elite Performers

INTRODUCTION. Why Write Yet Another Book on Psychological Preparation? CURRENT STATE OF KNOWLEDGE REGARDING PSYCHOLOGICAL PREPARATION FOR SPORTS PERFORMANCE. Basic Psychological Skills. Self-Confidence. Motivation. Arousal and Activation. Stress and Anxiety. Concentration and Attention Control. Coping with Adversity. IMPLICATIONS AND FUTURE DIRECTIONS. A Unifying Model of Psychological Preparation for Peak Athletic Performance. Future Research Directions. Implications for Guiding Practice.
Mortality Level and Predictors in a Rural Ethiopian Population: Community Based Longitudinal Study

Background Over the last fifty years the world has seen enormous decline in mortality rates. However, in low-income countries, where vital registration systems are absent, mortality statistics are not easily available. The recent economic growth of Ethiopia and the parallel large scale healthcare investments make investigating mortality figures worthwhile. Methods Longitudinal health and demographic surveillance data collected from September 11, 2009 to September 10, 2012 were analysed. We computed incidence of mortality, overall and stratified by background variables. Poisson regression was used to test for a linear trend in the standardized mortality rates. Cox-regression analysis was used to identify predictors of mortality. Households located at <2300 meter and ≥2300 meter altitude were defined to be midland and highland, respectively. Results An open cohort, with a baseline population of 66,438 individuals, was followed for three years to generate 194,083 person-years of observation. The crude mortality rate was 4.04 (95% CI: 3.77, 4.34) per 1,000 person-years. During the follow-up period, incidence of mortality significantly declined among under five (P<0.001) and 5–14 years old (P<0.001), whereas it increased among 65 years and above (P<0.001). Adjusted for other covariates, mortality was higher in males (hazard ratio (HR) = 1.42, 95% CI: 1.22, 1.66), rural population (HR = 1.74, 95% CI: 1.32, 2.31), highland (HR = 1.20, 95% CI: 1.03, 1.40) and among those widowed (HR = 2.25, 95% CI: 1.81, 2.80) and divorced (HR = 1.80, 95% CI: 1.30, 2.48). Conclusions Overall mortality rate was low. The level and patterns of mortality indicate changes in the epidemiology of major causes of death. Certain population groups had significantly higher mortality rates and further research is warranted to identify causes of higher mortality in those groups.