Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychometric Properties of the Problematic Online Gaming Questionnaire Short-Form and Prevalence of Problematic Online Gaming in a National Sample of Adolescents

The rise and growing popularity of online games has led to the appearance of excessive gaming that in some cases can lead to physical and psychological problems. Several measures have been developed to explore the nature and the scale of the phenomenon. However, few measures have been validated psychometrically. The aim of the present study was to test the psychometric properties of the 12-item Problematic Online Gaming Questionnaire Short-Form (POGQ-SF) and to assess the prevalence of problematic online gaming. Data collection was carried out to assess the prevalence of problematic online gaming in a national representative adolescent sample by using an offline (pen and pencil) method. A total of 5,045 secondary school students were assessed (51% male, mean age 16.4 years, SD=0.9 years) of which 2,804 were gamers (65.4% male, mean age 16.4 years, SD=0.9 years). Confirmatory factor analysis was applied to test the measurement model of problematic online gaming, and latent profile analysis was used to identify the proportion of gamers whose online game use can be considered problematic. Results showed that the original six-factor model yielded appropriate fit to the data, and thus the POGQ-SF has appropriate psychometric properties. Latent profile analysis revealed that 4.6% of the adolescents belong to a high risk group and an additional 13.3% to a low risk group. Due to its satisfactory psychometric characteristics, the 12-item POGQ-SF appears to be an adequate tool for the assessment of problematic online gaming.
Simulation-based comparison of four site-response estimation techniques

Recent earthquakes have triggered renewed interest to understand better earthquake site response. Most of the studies comparing various techniques for estimating site response were based on real data (from earthquakes, nuclear blasts, and seismic noise). A theoretical approach, using synthetic data generated with the pseudospectral method, is used to compare four site-response estimation techniques. The limits of applicability of each method were determined by modeling microtremors and incoming SV waves (with different incidence angles) and analyzing the site amplifications. The first two techniques investigated consist of dividing the spectrum of the horizontal motion at a site by that of a reference site using either incident S waves or microtremors. The latter was unable to reveal either the resonant frequencies or peak amplitudes in any cases. The two other techniques are based on the horizontal-to-vertical (H/V) spectral ratio using S waves or microtremors. These techniques were found to reveal at least the fundamental resonant frequency and amplitude (former method only) within 10% error, in the case of simple geology (flat layers). However, the results show that these techniques are unable to take into account 2D effects such as focusing effects and basin-edge effects and yield unreliable or incorrect results in such cases.
Extracellular cleavage of E-cadherin promotes epithelial cell extrusion

ABSTRACT Epithelial cell extrusion and subsequent apoptosis is a key mechanism to prevent the accumulation of excess cells. By contrast, when driven by oncogene expression, apical cell extrusion is followed by proliferation and represents an initial step of tumorigenesis. E-cadherin (E-cad), the main component of adherens junctions, has been shown to be essential for epithelial cell extrusion, but its mechanistic contribution remains unclear. Here, we provide clear evidence that cell extrusion can be driven by the cleavage of E-cad, both in a wild-type and an oncogenic environment. We first show that CDC42 activation in a single epithelial cell results in its efficient matrix metalloproteinase (MMP)-sensitive extrusion through MEK signalling activation and this is supported by E-cad cleavage. Second, using an engineered cleavable form of E-cad, we demonstrate that, by itself, truncation of extracellular E-cad at the plasma membrane promotes apical extrusion. We propose that extracellular cleavage of E-cad generates a rapid change in cell–cell adhesion that is sufficient to drive apical cell extrusion. Whereas in normal epithelia, extrusion is followed by apoptosis, when combined with active oncogenic signalling, it is coupled to cell proliferation.
“New” Holistic Mass Media Business Model

This qualitative case study, based on the principles of grounded theory, develops a holistic business model for media outlets by investigating the organizational structure and corporate culture of a unique agricultural radio station that operated successfully for over 60 years. It examines the station in the context of its founding era and determines the process used to create this survivor. An inductively generated “theory of commitment” is proposed, and guidelines are provided that could help today's independent media start-ups become survivors.
Towards Adaptation of Self and Other Versions of the Revised Power in Soccer Questionnaire for Turkey

Abstract The purpose of this study was to adapt the self and other versions of the Power in Sport Questionnaire for Turkey. Five sources of interpersonal power have been identified in the literature (reward, coercive, referent, legitimate and expert powers). These interpersonal powers were later adapted to sport settings and sound validity and reliability results have been shown in North America. Participants were 165 male soccer head coaches and 870 male soccer players (697 amateur and 173 professionals) in this study. Confirmatory and Exploratory factor analyses with the data collected in Turkey supported the four-factor model for coaches and players with the elimination of some items (items 1, 6, 7, 9 and 11). To some extent, cultural convergence and divergences appear to exist between both multicultural countries (USA and Turkey) related to perception of leadership power. Additional new items and models may be needed for soccer in Turkey.
A university library management model for students’ learning support

Abstract This research was aimed at developing a university library management model that would support students’ learning. The research was conducted in three phases: 1) an investigation into the requirements of a university library service of instructors; 2) an investigation into the attitudes of librarians, libraries’ administrators, and university’s administrators toward the roles of library and policy concepts relating to university library management that promote students’ learning; and 3) the development of a university library management model for students’ learning support. A mixed research method was applied comprising qualitative and quantitative approaches. Data was collected using in-depth interviews and questionnaires. The findings have led to a proposal of a university library management model that supports student learning, which is comprised of five components: 1) management policy and system; 2) learning resources; 3) learning support services; 4) learning environments; and 5) the competency and roles of information professionals. It can be stated that studies into Thai university library implementation, strategic plans, and self-assessment reports under the quality assurance system showed that even though libraries have updated resources and services following changing situations in policies, technologies, and users’ needs, there is no clear indicator that Thai university libraries have any strategy for acquiring roles to support students’ learning with practical outcomes. Through reliable research work, this study into a model for university library management would result in a means of developing university libraries that truly supports university student learning based on information from instructors, library administrators, and librarians.
Circadian Rhythmicity by Autocatalysis

The temperature compensated in vitro oscillation of cyanobacterial KaiC phosphorylation, the first example of a thermodynamically closed system showing circadian rhythmicity, only involves the three Kai proteins (KaiA, KaiB, and KaiC) and ATP. In this paper, we describe a model in which the KaiA- and KaiB-assisted autocatalytic phosphorylation and dephosphorylation of KaiC are the source for circadian rhythmicity. This model, based upon autocatalysis instead of transcription-translation negative feedback, shows temperature-compensated circadian limit-cycle oscillations with KaiC phosphorylation profiles and has period lengths and rate constant values that are consistent with experimental observations.
Biased Information Search in the Interpersonal Domain

An experiment was conducted to investigate the conditions under which people selectively seek information about other persons to provide an informational basis for desired positive or negative evaluations of those persons. It was hypothesized that active involvement in an interaction with another person is prerequisite to the occurrence of such biased search. Subjects either received or observed another subject receive a positive or negative evaluation from a confederate. After being led to expect that available information about the confederate was either mostly positive or mostly negative, their interest in acquiring such information was assessed. Subjects who were the recipients of the confederate's praise sought more information when they expected it to be positive than when they expected it to be negative; recipients of the confederate's criticism sought more information when they expected it to be negative than when they expected it to be positive. No hint of such biased search tendencies were found among observer subjects.
Harmonic metrics and connections with irregular singularities

We identify the holomorphic de Rham complex of the minimal extension of a meromorphic vector bundle with connexion on a compact Riemann surface X with the L^2 complex relative to a suitable metric on the bundle and a complete metric on the punctured Riemann surface. Applying results of C. Simpson, we show the existence of a harmonic metric on this vector bundle, giving the same L^2 complex. As a consequence, we obtain a Hard Lefschetz-type theorem.
Improving Phosphorus Availability in an Acid Soil Using Organic Amendments Produced from Agroindustrial Wastes

In acid soils, soluble inorganic phosphorus is fixed by aluminium and iron. To overcome this problem, acid soils are limed to fix aluminium and iron but this practice is not economical. The practice is also not environmentally friendly. This study was conducted to improve phosphorus availability using organic amendments (biochar and compost produced from chicken litter and pineapple leaves, resp.) to fix aluminium and iron instead of phosphorus. Amending soil with biochar or compost or a mixture of biochar and compost increased total phosphorus, available phosphorus, inorganic phosphorus fractions (soluble inorganic phosphorus, aluminium bound inorganic phosphorus, iron bound inorganic phosphorus, redundant soluble inorganic phosphorus, and calcium bound phosphorus), and organic phosphorus. This was possible because the organic amendments increased soil pH and reduced exchangeable acidity, exchangeable aluminium, and exchangeable iron. The findings suggest that the organic amendments altered soil chemical properties in a way that enhanced the availability of phosphorus in this study. The amendments effectively fixed aluminium and iron instead of phosphorus, thus rendering phosphorus available by keeping the inorganic phosphorus in a bioavailable labile phosphorus pool for a longer period compared with application of Triple Superphosphate without organic amendments.
The Effects of Constant External Resistance Exercise and Isokinetic Exercise Training on Work‐induced Hypertrophy

Six male subjects (26.0±3.1 years) performed an exercise regimen of repeated knee extension exercises in an attempt to induce size and strength changes in the quadriceps muscle (thigh). The left thigh was trained using a progressive constant external resistance exercise (CERE) lifting protocol and the right thigh was trained using an isokinetic (ISK) device. The total amount of torque produced by each protocol was the same. Knee extensions were performed at a velocity common to the CERE (120 deg/sec). Girth measurements, corrected for subcutaneous fat, and expressed as thigh volumes (cc), showed a significant hypertrophy of the posttrained CERE thigh (3300.67±526.67) compared to the pretrained CERE thigh (3044.13±448.50). No significant difference was found between pre- and posttrained ISK thigh volumes. The mean CERE (36.0±0.0) and ISK repetitions (64.54±13.61) necessary to produce equals work bouts (based on total torque produced) were significantly different. Strength gains as measured with the CERE and ISK device were specific to the training mode. The CERE thigh showed a significant strength (kg) gain when tested on a CERE device; the ISK thigh did not. However, the ISK thigh gained significant strength (kg.m) at all testing velocities (60, 180 and 240 deg/sec) while the CERE thigh did not. These data would indicate: 1) the suggested superiority of CERE training versus ISK training for producing hypertropby of the thigh at a training velocity common to CERE (120 deg/sec); 2) CERE training is more intense than ISK training for equal work bouts at a training velocity common to CERE; and 3) strength gains are specific to training and to the mode of testing.
Infliximab in primary Sjögren's syndrome: one-year followup.

OBJECTIVE To evaluate the safety and efficacy of a maintenance regimen of infliximab in patients with active primary Sjögren's syndrome (SS) over a 1-year period. METHODS This followup study included 10 of the 16 patients with primary SS who participated in a pilot study. Patients who continued to have symptoms received additional infusions of infliximab for 1 year. RESULTS All patients completed the 1-year followup for evaluation of efficacy. After 1 year, a statistically significant decrease in global and local disease manifestations was observed in all 10 patients. Treatment was generally well tolerated, with the main side effect being a mild, self-limited infusion reaction. CONCLUSION Sustained improvement of active primary SS may be possible with infliximab treatment.
A Class-AB/D Audio Power Amplifier for Mobile Applications Integrated Into a 2.5G/3G Baseband Processor

A filterless class-AB/D audio power amplifier integrated into a feature-rich 2.5G/3G baseband processor in standard 65-nm CMOS technology is designed for direct battery hookup in mobile phone applications. Circuit techniques are used to overcome the voltage limitations of standard MOS transistors for operation at voltage levels of 2.5-4.8 V. Both amplifiers can drive more than 650 mW into an 8-¿ load with maximum distortion levels of 1% and 5% for class-D and class-AB, respectively, all from a 3.6-V power supply. The achieved power-supply-rejection ratios are 72 and 84 dB, respectively. The mono implementation of both amplifiers together is 0.44 mm2 .
Structural ‘ Snapshots ’ of the Initiation of SV 40 Replication

The initiation of DNA replication, which is one of the fundamental processes in eukaryotic cells, is not understood at the molecular level. Therefore, several laboratories are attempting to understand this process using the simian virus 40 replication system; a relatively simple and well-characterized model for studies of eukaryotic DNA replication. The replication initiator encoded by simian virus 40 is termed T-antigen. Molecular structures have been obtained for the three major domains of T-antigen. Moreover, several structures are now available of the central ‘origin binding domain’ in complex with various DNA substrates. Collectively these structures have provided a series of ‘snap-shots’ of the initiation process. They have also significantly improved our understanding of such diverse processes as site specific binding during origin recognition, melting of origin sequences, oligomerization of T-antigen (to form hexamers and double hexamers) and the molecular basis for helicase activity.
Overweight Nova Scotia children and youth: the roles of household income and adherence to Canada's Food Guide to Healthy Eating.

OBJECTIVE Poor diet quality has been observed in Nova Scotia children and youth, characterized by low intake from the traditional four food groups and a high intake from the Other Foods category. In this study, we addressed how household income and adherence to Canada's Food Guide to Healthy Eating influenced weight status category in Nova Scotia children and youth. METHODS During the 2005-06 school year, data were collected from 2,296 students and their parents, across Nova Scotia. Questionnaires and anthropometric measurements were obtained from grades 3, 7 and 11 students. The grade 3 students were excluded from the dietary intake assessment. The information collected from the online 24-hour food recalls and food frequency questionnaires were analyzed for adherence to Canada's Food Guide to Healthy Eating recommendations. A general linear model was employed to examine the relationships between household income, food group and weight status category. RESULTS Overall adherence to Canada's Food Guide to Healthy Eating was low among grades 7 and 11 students. Fewer servings from Grain Products, Milk Products and Vegetables and Fruit were observed in at risk of overweight and overweight students. At risk of overweight and overweight were significantly related to lower household income in grades 3 and 11. Our results show that the rates of overweight in Nova Scotia students are double those reported by the 2004 Canadian Community Health Survey. CONCLUSION Household income and dietary intake play significant roles in weight status among Nova Scotia children and youth.
Ten-year all-cause mortality in hospitalized non-surgical patients based on nutritional status screening

Abstract Objective Malnutrition is common in patients admitted to hospital due to acute illness and contributes to negative patient outcomes. In Slovakia there is a lack of relevant data on malnutrition in hospitalized patients, particularly based on chronic co-morbidity and survival. The aim of the present study was to explore the prevalence of malnutrition in hospitalized chronic patients, its relationship to co-morbidity and its impact on 10-year survival. Design Retrospective cohort study. Setting Nutritional status was estimated by Subjective Global Assessment (SGA), BMI and serum albumin level. Survival was assessed from the National Insurance Registry over a 10-year period. The association between nutritional status measured by SGA and 10-year survival controlling for age, gender, BMI and serum albumin was analysed using Cox regression. Subjects Data were taken from the medical records of 202 consecutively admitted chronic patients. Results Median age was 63·5 years; 55·4 % were males; median BMI was 25·9 kg/m2; median serum albumin level was 39·0 g/l. Based on SGA evaluation, 38·1 % did not have sufficient nutritional status (SGA classification B and C). Malnutrition was more common in patients who were older (P=0·023), with lower BMI (P<0·001), who had gastrointestinal (P=0·049) and oncologic co-morbidity (P=0·021) and lower albumin level (P=0·049). In-hospital mortality was 3 %, but during the following 10 years 52 % died. Cox regression analysis controlling for age, gender, BMI and serum albumin showed that SGA was an independent predictor of death (hazard ratio=1·55; 95 % CI 1·04, 2·32; P=0·031). Conclusions SGA is a simple screening tool that can be routinely used in hospitalized Slovak medical patients to predict the risk of death. Improving patient nutrition could thus reduce mortality.
The Role of DJ-1 in the Pathogenesis of Endometriosis

Background Endometriosis is an estrogen-dependent disease causing pelvic pain and infertility in 10% of reproductive-aged women. Despite a long history of the disease the pathogenesis of endometriosis is poorly understood. It is known that the expression of several proteins is either up or down regulated during endometriosis, but their precise role remains to be determined. DJ-1 is one such protein that is upregulated in eutopic endometrium of women having endometriosis suggesting that DJ-1 may be involved in the pathogenesis of endometriosis. Methodology and Principal Findings The role of DJ-1 in the pathogenesis of endometriosis was investigated. For this purpose the influence of DJ-1 on endometrial cell survival, attachment, proliferation, migration, and invasion either by overexpressing DJ-1 in normal endometrial cells or by knocking down DJ-1 expression in endometriotic cells using siRNA was investigated. The results indicated that DJ-1 protects endometrial cells from oxidative stress mediated apoptosis. Overexpression of DJ-1 in normal endometrial epithelial cells increases the adhesion on collagen type IV. However, no significant difference was observed incase of stromal cells. It was further demonstrated that DJ-1 regulates cell proliferation, migration, and invasion in normal endometrial and endometriotic epithelial cells whereas in the case of normal endometrial and endometriotic stromal cells, it regulates cell proliferation and invasion but not migration. Furthermore, the present study also indicated that DJ-1 regulates these cellular processes by modulating PI3K/Akt pathway by interacting and negatively regulating PTEN. Conclusions Abnormally high levels of DJ-1 expression may be involved in endometriosis, possibly by stimulating endometrial cell survival, proliferation, migration, and invasion.
Concept Map Assessment of Classroom Learning: Reliability, Validity, and Logistical Practicality

The psychometric characteristics and practicality of concept mapping as a technique for classroom assessment were evaluated. Subjects received 90 min of training in concept mapping techniques and were given a list of terms and asked to produce a concept map. The list of terms was from a course in which they were enrolled. The maps were scored by pairs of graduate students, each pair using one of six different scoring methods. The score reliability of the six scoring methods ranged from r 5 . 23 to r 5 . 76. The highest score reliability was found for the method based on the evaluation of separate proposi- tions represented. Correlations of map scores with a measure of the concept maps' similarity to a master map provided evidence supporting the validity of five of the six scoring methods. The times required to provide training in concept mapping, produce concepts, and score concept maps were compatible with the adoption of concept mapping as classroom assessment technique. © 1999 John Wiley & Sons, Inc. J Res Sci Teach 36: 475 -492, 1999