Miracle-dz/UniFAR-FTUs huggingface dataset:
Internal iliac occlusion without coil embolization during endovascular abdominal aortic aneurysm repair.

PURPOSE When abdominal aortic aneurysms and common iliac artery (CIA) aneurysms undergo concomitant endovascular repair, endograft limb extension into the external iliac artery is often necessary. Usually, the internal iliac artery (IIA) is coil embolized in such a case to prevent endoleak. It has been our practice to coil embolize the IIA only in cases where there is not adequate stent graft seal in the CIA immediately proximal to the IIA origin (effectively sealing the entire IIA origin). In this study, we evaluated the outcomes of this approach. METHODS We retrospectively reviewed 204 consecutive endovascular abdominal aortic aneurysm repairs at Dartmouth-Hitchcock Medical Center from 1996 to 2001. Computed tomographic angiography with three-dimensional reconstruction was the primary preoperative imaging modality, and the decision to cover the IIA without concomitant coil embolization was based before surgery on the presence of adequate graft oversizing (> or =10% to 15%) in the most distal 5 mm of CIA and 15 mm of proximal external iliac artery, respectively. RESULTS The IIA was occluded 33 times in 31 patients. In 22 cases (67%), the IIA was covered without coil embolization (COVER group). The remaining 11 patients (33%) with inadequate graft oversizing in the CIA underwent IIA coil embolization (COIL group). The follow-up periods for the COVER and COIL groups were 19 +/- 2 months and 10 +/- 3 months, respectively. All operations in both groups were technically successful without evidence of endoleak at completion angiography. No endoleaks, graft migrations, or aneurysm enlargements were associated with the covered or coiled IIAs during the follow-up period. No clinical sequelae were seen in the COVER group, with the exception of buttock claudication in six patients (27%) that resolved completely in five patients. In the COIL group, five patients (45%) had buttock claudication. In addition, one case of buttock necrosis and one case of ischemic neuropathy occurred in the COIL group. CONCLUSION Covering the IIA without coiling effectively excluded the CIA aneurysm in every case and was associated with a low incidence rate of complications compared with coil embolization. With detailed preoperative imaging and patient selection, IIA coil embolization may not be necessary in as many as two thirds of patients who need IIA occlusion.
Towards a cross-modal perspective of emotional perception in social anxiety: review and future directions

The excessive fear of being negatively evaluated constitutes a central component of social anxiety (SA). Models posit that selective attention to threat and biased interpretations of ambiguous stimuli contribute to the maintenance of this psychopathology. There is strong support for the existence of processing biases but most of the available evidence comes from face research. Emotions are, however, not only conveyed through facial cues, but also through other channels, such as vocal and postural cues. These non-facial cues have yet received much less attention. We therefore plead for a cross-modal investigation of biases in SA. We argue that the inclusion of new modalities may be an efficient research tool to (1) address the specificity or generalizability of these biases; (2) offer an insight into the potential influence of SA on cross-modal processes; (3) operationalize emotional ambiguity by manipulating cross-modal emotional congruency; (4) inform the debate about the role of top-down and bottom-up factors in biasing attention; and (5) probe the cross-modal generalizability of cognitive training. Theoretical and clinical implications as well as potential fruitful avenues for research are discussed.
Views and attitudes of staff and students towards the significance of intercultural awareness in foreign language teaching and learning in an Australian university context

Globalisation is influencing foreign language education at universities worldwide. People now live in an increasingly multicultural world where different cultural practices have blended. Thus, intercultural awareness has now become a vital part of foreign language learning. The aim of the study was to investigate teachers’ and students’ beliefs and understandings of the significance of intercultural awareness in foreign language teaching and learning in a university context. As the study was situated within the Tasmanian context, it sought to provide contextual information and implications meaningful and appropriate to the local language learning environment. The investigation focused on three areas: generalising the participants’ perceptions of the importance of intercultural awareness in general; examining their intercultural experiences, personally and professionally, especially in relation to language teaching and learning; and identifying the factors that influenced the way they teach and learn. The study employed both quantitative and qualitative research approaches for data collection and analysis. It included two phases: questionnaire survey and subsequent interview. The statistical data were analysed using the SPSS (Statistical Package for the Social Science) software version 20.0. The textual data collected from the interviews were analysed using the NVivo qualitative data software version 10.0. Thematic analysis was used in the qualitative data analysis. The results of this study indicated strong recognition of the key role that intercultural awareness plays in foreign language teaching and learning. Based on the findings, pedagogical implications and directions for further research were also addressed. The findings suggested that language learners should cultivate intercultural awareness in the process of their language learning as it is considered the major goal of foreign language learning. Meanwhile, teachers’ intercultural awareness could influence their language teaching methodology and course design. A paradigm shift from a traditional to an intercultural stance in language education poses a challenge for both language teachers and students if they wish to meet the goals of foreign language education for the global context.
Gait variability and symmetry in world-class senior and junior race walkers

ABSTRACT The aim of this study was to analyse gait variability and symmetry in race walkers. Eighteen senior and 17 junior athletes race walked on an instrumented treadmill (for 10 km and 5 km, respectively) at speeds equivalent to 103% of season’s best time for 20 km and 10 km, respectively. Spatio-temporal and ground reaction force (GRF) data were recorded at 2.5 km, and at 4.5, 6.5 and 8.5 km for a subsection of athletes. Gait variability was measured using median absolute deviation (MAD) whereas inter-leg symmetry was measured using the symmetry angle. Both groups showed low variability for step length (<0.9%), step frequency (<1.1%), contact time (≤1.2%) and vertical peak force values (<5%), and neither variability nor symmetry changed with distance walked. Junior athletes were more variable for both step length (P = 0.004) and loading force (P = 0.003); no differences for gait symmetry were found. Whereas there was little mean asymmetry overall, individual analyses identified asymmetry in several athletes (symmetry angle ≥ 1.2%). Importantly, asymmetrical step lengths were found in 12 athletes and could result from underlying imbalances. Coaches are advised to observe athletes on an individual basis to monitor for both variability and asymmetry.
Extremely low-frequency magnetic fields can impair spermatogenesis recovery after reversible testicular damage induced by heat

Abstract Male infertility is often related to reproductive age couples experiencing fertility-related issues. Men may have fertility problems associated with reversible testicular damage. Considering that men have been increasingly exposed to extremely low-frequency magnetic fields generated by the production, distribution and use of electricity, this study analyzed whether 60 Hz and 1 mT magnetic field exposure may impair spermatogenesis recovery after reversible testicular damage induced by heat shock using rats as an experimental model. Adult male rats were subjected to a single testicular heat shock (HS, 43 °C for 12 min) and then exposed to the magnetic field for 15, 30 and 60 d after HS. Magnetic field exposure during the spermatogenesis recovery induced changes in testis components volume, cell ultrastructure and histomorphometrical parameters. Control animals had a reestablished and active spermatogenesis at 60 d after heat shock, while animals exposed to magnetic field still showed extensive testicular degeneration. Magnetic field exposure did not change the plasma testosterone. In conclusion, extremely low-frequency magnetic field may be harmful to fertility recovery in males affected by reversible testicular damage.
Physiologically‐Based Pharmacokinetic Modeling of Genistein in Rats, Part I: Model Development

Genistein is a phytoestrogen—a plant‐derived compound that binds to and activates the estrogen receptor—occurring at high levels in soy beans and food products, leading to widespread human exposure. The numerous scientific publications available describing genistein's dosimetry, mechanisms of action, and identified or putative health effects in both experimental animals and humans make it ideal for examination as an example of endocrine‐active compound (EAC). We developed a physiologically‐based pharmacokinetic (PBPK) model to quantify the internal, target‐tissue dosimetry of genistein in adult rats. Complexities of the model include enterohepatic circulation, binding of both genistein and its conjugates to plasma proteins, and the multiple compartments used to describe transport through the bile duct and gastrointestinal tract. Other aspects of the model are simple perfusion‐limited transport to the tissue groups and first‐order rates of metabolism, uptake, and excretion. We describe here the model structure and initial calibration of the model by fitting to a large data set for Wistar rats. The model structure can be readily extrapolated to describe genistein dosimetry in humans or modified to describe the dosimetry of other phytoestrogens and phenolic EACs. The model does a fair job of capturing the pharmacokinetics. Although it does not describe the interindividual variability and we have not identified a single set of parameters that provide a good fit to the data for both oral and intravenous exposures, we believe it provides a good initial attempt at PBPK modeling for genistein, which can serve as a template for other phytoestrogens and in the design of future experiments and research that can be used to fill data gaps and better estimate model parameters.
Pengaruh Model Pembelajaran Matematika Creative Problem Solving (Cps) Berbantuan Cd Interaktif Terhadap Kemampuan Pemecahan Masalah Pada Siswa SMA

ABSTRACT Problem solving ability is the main objective of mathematics learning. In conventional learning currently still dominant in Indonesia, most of the students are accustomed to memorizing without any development of problem solving ability. One kind of learning model could assist learners to practice solving problems is Creative Problem Solving (CPS) model assisted with interactive CD. This research is aimed to find out whether the problem solving for students joining CPS model assisted with interactive CD has betterment that those joining the conventional one, and whether arise difference among upper, middle, and lower group students in the learning. This research is a quasi experimental research, with all the population of grade X regular students of Senior High School 1 Semarang in the academic year 2010/ 2011. As samples, several students were taken randomly, one class as experiment and the other as a control one. The measuring instruments used were problem solving tests. The data were analyzed by the use analysis independent sample t test, and compare means one way anova. The results of the research show that problem solving ability of the students joining the CPS model assisted with interactive CD is better than those joining the conventional one, and there is difference problem solving ability among upper, middle, and lower group students in the learning. Therefore, this model could be applied as an effective alternative learning model to reach problem solving ability maximally, especially on the subject trigonometry grade X. Pengaruh Model Pembelajaran Matematika Creative Problem Solving (CPS) … (Suparman) Key words: Problem Solving, CPS, Interactive CD, Creative.
Finding Cool Subdwarfs Using a V−J Reduced Proper‐Motion Diagram: Stellar Parameters for 91 Candidates

We present the results of a search for cool subdwarfs for which our candidates were drawn from a V−J reduced proper‐motion diagram constructed by Salim & Gould. Kinematic (U, V, and W) and self‐consistent stellar parameters (Teff, log g, [Fe/H], and ξt) are derived for 91 candidate subdwarfs based on high‐resolution spectra. The observed stars span 3900 K < Teff < 6200 K and −2.63 < [Fe/H] < 0.25 including only three giants (log g < 4.0). Of the sample, 77 stars have MgH lines present in their spectra. With more than 56% of our candidate subdwarfs having [Fe/H] ≤ −1.5, we show that the V−J reduced proper‐motion diagram readily identifies metal‐poor stars.
Parkinson's Disease Prevalence and Proximity to Agricultural Cultivated Fields

The risk for developing Parkinson's disease (PD) is a combination of multiple environmental and genetic factors. The Negev (Southern Israel) contains approximately 252.5 km2 of agricultural cultivated fields (ACF). We aimed to estimate the prevalence and incidence of PD and to examine possible geographical clustering and associations with agricultural exposures. We screened all “Clalit” Health Services members in the Negev (70% of the population) between the years 2000 and 2012. Individual demographic, clinical, and medication prescription data were available. We used a refined medication tracer algorithm to identify PD patients. We used mixed Poisson models to calculate the smoothed standardized incidence rates (SIRs) for each locality. We identified ACF and calculate the size and distance of the fields from each locality. We identified 3,792 cases of PD. SIRs were higher than expected in Jewish rural localities (median SIR [95% CI]: 1.41 [1.28; 1.53] in 2001–2004, 1.62 [1.48; 1.76] in 2005–2008, and 1.57 [1.44; 1.80] in 2009–2012). Highest SIR was observed in localities located in proximity to large ACF (SIR 1.54, 95% CI 1.32; 1.79). In conclusion, in this population based study we found that PD SIRs were higher than expected in rural localities. Furthermore, it appears that proximity to ACF and the field size contribute to PD risk.
Learning Shallow Detection Cascades for Wearable Sensor-Based Mobile Health Applications

The field of mobile health aims to leverage recent advances in wearable on-body sensing technology and smart phone computing capabilities to develop systems that can monitor health states and deliver just-in-time adaptive interventions. However, existing work has largely focused on analyzing collected data in the off-line setting. In this paper, we propose a novel approach to learning shallow detection cascades developed explicitly for use in a real-time wearable-phone or wearable-phone-cloud systems. We apply our approach to the problem of cigarette smoking detection from a combination of wrist-worn actigraphy data and respiration chest band data using two and three stage cascades.
A poor man’s BLASTX—high-throughput metagenomic protein database search using PAUDA

Summary: In the context of metagenomics, we introduce a new approach to protein database search called PAUDA, which runs ∼10 000 times faster than BLASTX, while achieving about one-third of the assignment rate of reads to KEGG orthology groups, and producing gene and taxon abundance profiles that are highly correlated to those obtained with BLASTX. PAUDA requires <80 CPU hours to analyze a dataset of 246 million Illumina DNA reads from permafrost soil for which a previous BLASTX analysis (on a subset of 176 million reads) reportedly required 800 000 CPU hours, leading to the same clustering of samples by functional profiles. Availability: PAUDA is freely available from: http://ab.inf. uni-tuebingen.de/software/pauda. Also supplementary method details are available from this website. Contact: daniel.huson@uni-tuebingen.de or xiechao@bic.nus. edu.sg
The insertion/deletion polymorphism of the angiotensin-converting enzyme gene is associated with progression, but not development, of albuminuria in Iranian patients with type 2 diabetes

Introduction. The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene has been shown to be associated with a number of complications of type 2 diabetes. Results on the development and progression of albuminuria, however, have remained controversial, with ethnic differences being a potential reason.The present study is the first report to examine Iranian patients. Methods. Patients (322; 162 males) with type 2 diabetes were categorised in this cross-sectional study into the following groups: normoalbuminuria (n=145), microalbuminuria (n=129) and macroalbuminuria (n=48). ACE gen I/D polymorphism genotypes were determined using the polymerase chain reaction method. Results. The distribution of ACE genotypes was significantly different among the groups (p<0.001), with the II genotype decreasing and the DD genotype increasing in frequency with increasing severity of albuminuria. Multivariate regression analysis showed that the ACE genotype did not change the odds of having microalbuminuria versus normoalbuminuria, while the D allele independently increased the odds of having macroalbuminuria versus microalbuminuria approximately threefold (p<0.01). Conclusions. In Iranian patients with type 2 diabetes, the D allele is associated with progression, but not development, of albuminuria.
Five Cases of Non-Hodgkin B-Cell Lymphoma of the Ovary

The involvement of the ovary in lymphomatous process is rare. Such an involvement may occur in 2 ways, primary or secondary. We report 5 cases of ovarian non-Hodgkin's lymphoma, with 3 of which primarily arising in the ovaries. Ovarian lymphoma can mimic more frequently occurring tumors including advanced epithelial carcinoma and radical surgery may be performed instead of a biopsy. The immunophenotypic and clinicopathologic features exhibited in this small series are described to call attention to early diagnosis and treatment of ovarian lymphoma. All patients were diagnosed as having DLBCL after ovary biopsy. Different treatment modalities were used and prognosis of the patients was reported.
A General Micro-Level Modeling Approach to Analyzing Interconnected SDGs: Achieving SDG 6 and More through Multiple-Use Water Services (MUS)

The 2030 agenda presents an integrated set of Sustainable Development Goals (SDGs) and targets that will shape development activities for the coming decade. The challenge now facing development organizations and governments is how to operationalize this interconnected set of goals and targets through effective projects and programs. This paper presents a micro-level modeling approach that can quantitatively assess the impacts associated with rural water interventions that are tailored to specific communities. The analysis focuses on how a multiple-use water services (MUS) approach to SDG 6 could reinforce a wide range of other SDGs and targets. The multilevel modeling framework provides a generalizable template that can be used in multiple sectors. In this paper, we apply the methodology to a dataset on rural water services from Mozambique to show that community-specific equivalents of macro-level variables used in the literature such as Cost of Illness (COI) avoided can provide a better indication of the impacts of a specific intervention. The proposed modeling framework presents a new frontier for designing projects in any sector that address the specific needs of communities, while also leveraging the knowledge gained from previous projects in any country. The approach also presents a way for agencies and organizations to design projects or programs that bridge sectors/disciplines (water, irrigation, health, energy, economic development, etc.) to advance an interconnected set of SDGs and targets.
Studies on the chemicals required to induce alterations of morphology and growth potential in human cell culture.

An analysis of a trypsin-antibiotic solution to determine which chemicals were required for the prompt and irreversible alteration of fibroblastic-like cells to epithelioid forms indicated that trypsin in Puck's saline A, mycostatin, neomycin, and ten essential amino acids were involved in the “transformation” process. The removal of any one of the thirteen ingredients or the addition of calcium and/or magnesium ions prevented the alteration phenomenon. The optimum concentrations of the essential chemicals were determined. A direct relationship was found to exist between the concentration of trypsin which induced cell alteration and the concentrations of calcium and magnesium ions which inhibited the conversion process. The results are discussed with reference to the possible origins of the alterable fibroblastic-like cells, as well as the possible mechanisms responsible for the alteration phenomenon.
Very Isolated Early-Type Galaxies

We use the Karachentseva Catalogue of Very Isolated Galaxies to investigate a candidate list of more than 100 very isolated early-type galaxies. Broadband imaging and low-resolution spectroscopy are available for a large fraction of these candidates and result in a sample of 102 very isolated early-type galaxies, including 65 elliptical (E) and 37 S0 galaxies. Many of these systems are quite luminous, and the resulting optical luminosity functions of the E and early-type (E+S0) galaxies show no statistical differences when compared to luminosity functions dominated by group and cluster galaxies. However, whereas S0 galaxies outnumber E galaxies 4 : 1 in the CfA survey, isolated E outnumber S0 galaxies by nearly 2 : 1. We conclude that very isolated elliptical galaxies show no evidence of a different formation and/or evolution process compared to those formed in groups or clusters, but that most S0 galaxies are formed by a mechanism (e.g., gas stripping) that occurs only in groups and rich clusters. Our luminosity function results for elliptical galaxies are consistent with very isolated elliptical galaxies being formed by merger events, in which no companions remain. Chandra observations were proposed specifically to test the merger hypothesis for isolated elliptical galaxies. However, this program has resulted in the observation of only one isolated early-type galaxy, the S0 KIG 284, which was not detected at a limit well below that expected for a remnant group of galaxies. Therefore, the hypothesis remains untested that very isolated elliptical galaxies are the remains of a compact group of galaxies that have completely merged.
Immigrants and Native Workers New Analysis Using Longitudinal Employer-Employee Data

Using a database that includes the universe of individuals and establishments in Denmark over the period 1991-2008 we analyze the eect of a large inow of non-European (EU) immigrants on Danish workers. We rst identify a sharp and sustained supply-driven increase in the inow of non-EU immigrants in Denmark, beginning in 1995 and driven by a sequence of international events such as the Bosnian, Somalian and Iraqi crises. We then look at the response of occupational complexity, job upgrading and downgrading, wage and employment of natives in the short and long run. We nd that the increased supply of non-EU low skilled immigrants pushed native workers to pursue more complex occupations. This reallocation happened mainly through movement across rms. Immigration increased mobility of natives across rms and across municipalities but it did not increase their probability of unemployment. We also observe a signicant