Miracle-dz/UniFAR-FTUs huggingface dataset:
Reach adaptation and proprioceptive recalibration following terminal visual feedback of the hand

We have shown that when subjects reach with continuous, misaligned visual feedback of their hand, their reaches are adapted and proprioceptive sense of hand position is recalibrated to partially match the visual feedback (Salomonczyk et al., 2011). It is unclear if similar changes arise after reaching with visual feedback that is provided only at the end of the reach (i.e., terminal feedback), when there are shorter temporal intervals for subjects to experience concurrent visual and proprioceptive feedback. Subjects reached to targets with an aligned hand-cursor that provided visual feedback at the end of each reach movement across a 99-trial training block, and with a rotated cursor over three successive blocks of 99 trials each. After each block, no cursor reaches, to measure aftereffects, and felt hand positions were measured. Felt hand position was determined by having subjects indicate the position of their unseen hand relative to a reference marker. We found that subjects adapted their reaches following training with rotated terminal visual feedback, yet slightly less (i.e., reach aftereffects were smaller), than subjects from a previous study who experienced continuous visual feedback. Nonetheless, current subjects recalibrated their sense of felt hand position in the direction of the altered visual feedback, but this proprioceptive change increased incrementally over the three rotated training blocks. Final proprioceptive recalibration levels were comparable to our previous studies in which subjects performed the same task with continuous visual feedback. Thus, compared to reach training with continuous, but altered visual feedback, subjects who received terminal altered visual feedback of the hand produced significant but smaller reach aftereffects and similar changes in hand proprioception when given extra training. Taken together, results suggest that terminal feedback of the hand is sufficient to drive motor adaptation, and also proprioceptive recalibration.
GLMP- realtime pedestrian path prediction using global and local movement patterns

We present a novel real-time algorithm to predict the path of pedestrians in cluttered environments. Our approach makes no assumption about pedestrian motion or crowd density, and is useful for short-term as well as long-term prediction. We interactively learn the characteristics of pedestrian motion and movement patterns from 2D trajectories using Bayesian inference. These include local movement patterns corresponding to the current and preferred velocities and global characteristics such as entry points and movement features. Our approach involves no precomputation and we demonstrate the real-time performance of our prediction algorithm on sparse and noisy trajectory data extracted from dense indoor and outdoor crowd videos. The combination of local and global movement patterns can improve the accuracy of long-term prediction by 12-18% over prior methods in high-density videos.
Ori Gi Nal Ar Tic Le Ad Dress for Cor Res Pon Den Ce

What is already knoWn on this topic? What this study adds? Birth prevalence of primary congenital hypothyroidism (CH) was found to be very high in Turkey after the national screening. However, the incidence rates of permanent and transient CH are unknown due to lack of follow-up data. To distinguish between transient and permanent forms, the guidelines recommend that the children with unexplained CH be re-evaluated after 3 years of age through a trial of treatment withdrawal. Transient hypothyroidism exists in more than half of the newborns detected at screening in our region and most probably throughout the country. Lowering of thyroid stimulating hormone cutoffs has led to increased birth prevalence owing to detection of a higher number of mild cases of both permanent and transient CH. In the majority of cases, discrimination between transient and permanent CH could be possible before 3 years of age. This study has shown that unnecessary treatment of transient CH can be avoided in many infants owing to early cessation of low dose L-thyroxine. ©Jo ur nal of Cli ni cal Re se arch in Pe di at ric En doc ri no logy, Pub lis hed by Ga le nos Pub lis hing. Objective: Prevalence of congenital hypothyroidism (CH) in Turkey at birth was reported to be as high as 1:650 in 2008-2010. Incidence rates of permanent and transient CH separately are unknown due to lack of follow-up data. We aimed to evaluate the impact of transient hypothyroidism on increasing incidence of CH and to determine the natural course and the clinical, biochemical, and imaging characteristics of transient CH. Methods: Baseline and follow-up data of the infants with CH detected at screening in six provinces in the Black Sea Region were analyzed retrospectively during a time period covering the years 2008-2010. Results: Among 138 cases (48% female), 16 (12%) showed transient hyperthyrotropinemia which resolved without intervention. Of the treated 122 cases, 63 (52%) had transient CH. While its frequency was 35% in 2008, it increased to 56% in 2009-2010, following a lowering of the thyroid stimulating hormone cutoff value. The frequency was higher in inland provinces than in coast (67% vs. 43%; p=0.01). Clinical characteristics of permanent and transient cases were similar except female-to-male sex ratios (1.5:1 vs. 0.6:1; p=0.02). L-thyroxine was discontinued in 70% of transient cases before 3 years of age at a median age of 19 (2-36) months. The only indication …
Cephalosporin resistance mechanisms in Escherichia coli isolated from raw chicken imported into the UK.

OBJECTIVES We characterized mechanisms of resistance to oxyimino-cephalosporins in Escherichia coli isolated from raw chicken meat imported into the UK from South America, to ascertain whether this foodstuff contributes to the dissemination in the UK of extended-spectrum β-lactamase (ESBL)-producing E. coli belonging to the international uropathogenic ST131 clone. METHODS Sampling and collection of imported raw chicken meat was performed in accordance with regulatory guidelines by the London Port Health Authority at Tilbury. E. coli strains producing ESBLs were isolated based on growth within the zones of cefpodoxime (10 μg) discs. MICs were determined by agar dilution and interpreted using BSAC/EUCAST breakpoints. PCR was used to determine the phylogenetic groups of E. coli, to detect ESBL genes and to determine the incompatibility groups of plasmids encoding CTX-M enzymes. The molecular environments surrounding bla(CTX-M) were determined by DNA sequencing and PCR mapping. RESULTS A total of 141 oxyimino-cephalosporin-resistant E. coli were isolated from 62 of 210 batches of imported raw chicken sampled. Thirty percent of these isolates produced group 2 CTX-M ESBLs, 27% produced group 8 CTX-M ESBLs, 42% produced CMY-type AmpC enzymes and 1% produced a group 2 CTX-M along with a CMY enzyme; none produced CTX-M-15 ESBL and none belonged to the ST131 clone. In contrast to human clinical ESBL E. coli, >90% of isolates were susceptible to ciprofloxacin and 74% to all aminoglycosides. CONCLUSIONS Raw chicken imported into the UK from South America commonly carries ESBL-producing E. coli, but is not a significant source for the ST131 clone or for the CTX-M-15 ESBL.
AUTOMATIC EXTRACTION OF GO GAME POSITIONS FROM IMAGES: A MULTI-STRATEGICAL APPROACH TO CONSTRAINED MULTI-OBJECT RECOGNITION

Here we present a constrained object recognition task that has been robustly solved largely with simple machine learning methods, using a small corpus of about 100 images taken under a variety of lighting conditions. The task was to analyze images from a hand-held mobile phone camera showing an endgame position for the Japanese board game Go. The presented system would already be sufficient to reconstruct the full Go game record from a video record of the game and thus is complementary to Seewald (2003), which focuses on solving the same task using different sensors. The presented system is robust to a variety of lighting conditions, works with cheap low-quality cameras, and is resistant to changes in board or camera position without the need for any manual calibration.
Equine-assisted social work counteracts self-stigmatisation in self-harming adolescents and facilitates a moment of silence

Abstract The purpose of this study was to determine whether equine-assisted social work (EASW) could affect self-stigmatisation and thereby counteract false identities in self-harming adolescents. Data were collected via interviews with nine female self-harming clients aged 15–21 years and eight staff members. Interviews and video-recorded human–horse interactions with three staff members and four clients were analysed. The interviews were followed by further dialogue with participants while they viewed videos of their own EASW sessions. The analysis indicated that the horse had a calming effect on the clients; enabled them to free themselves of their preoccupations; provided real-time, non-verbal and non-judgmental feedback on their emotions; and increased feelings of trust, patience and empathy. The presence of a horse provided a ‘moment of silence’ for the clients, silencing their inner critic, and made them feel more authentic and better able to regulate their emotions. However, staff could counteract this ‘safe’ healing by being too focused on goals, making interpretations and lecturing and encouraging clients, thus making clients feel judged anyhow. EASW seemed to give clients the opportunity to break free from self-stigmatisation, which seemed to lower the barrier to change.
FREE-ENERGY-DISSIPATIVE SCHEMES FOR THE OLDROYD-B MODEL

In this article, we analyze the stability of various numerical schemes for diﬀerential models of viscoelastic ﬂuids. More precisely, we consider the prototypical Oldroyd-B model, for which a free energy dissipation holds, and we show under which assumptions such a dissipation is also satisﬁed for the numerical scheme. Among the numerical schemes we analyze, we consider some discretizations based on the log-formulation of the Oldroyd-B system proposed by Fattal and Kupferman, which have been reported to be numerically more stable than discretizations of the usual formulation in some benchmark problems. Our analysis gives some tracks to understand these numerical observations.
Very extended Kac Moody algebras and their interpretation at low levels

We analyse the very extended Kac–Moody algebras as representations in terms of certain Ad−1 subalgebras and find the generators at low levels. Our results for low levels agree precisely with the bosonic field content of the theories containing gravity, forms and scalars which upon reduction to three dimensions can be described by a nonlinear realization. We explain how the Dynkin diagrams of the very extended algebras encode information about the field content and generalized T-duality transformations.
Afut1, a retrotransposon-like element from Aspergillus fumigatus.

A repeated DNA sequence used for epidemiological studies of the human opportunistic pathogen Aspergillus fumigatus has been characterized. It is a retroelement of 6914 bp in length, bounded by long terminal repeats of 282 bp, with sequence and features characteristic of retroviruses and retrotransposons. A 5 bp duplication site was found at its borders. This element, designated Afut1, encodes amino acid sequences homologous to the reverse transcriptase, RNase H and endonuclease encoded by the pol genes of retroelements. Comparison of the peptidic sequences with other putative polypeptides of fungal LTR retrotransposons showed that Afut1 is a member of the gypsy group. This is the first report of a transposable element in A.fumigatus. Afut1 is a defective element: the putative coding domains contain multiple stop codons due exclusively to transitions from C:G to T:A.
Labor Market Policies and EU Accession: Problems and Prospects for Turkey

The process of European Union Accession has provided a strong stimulus for various institutional changes in Turkey. The European Council decision taken at Helsinki (10-11 December 1999) was an important turning point in this process. The Accession Partnership, which followed the Helsinki summit, identified short and medium term priorities, intermediate objectives and conditions on which accession preparations must concentrate in the light of the political and economic criteria. One of the most important issues for Turkey regarding the adoption and implementation of the Community acquis is related with the labor market regulations and employment policies. The adoption of the Community acquis will certainly bring radical changes in the functioning of the labor market in Turkey with vital consequences for firms, and workers, as well as the long-term performance of the economy. The aim of this study is to provide information for the use of these agents on the employment and labor market issues that are important during the EU accession process. Since the topic is rather broad, the current study has concentrated upon the possible effects of the adoption of the employment acquis regulating work and employment conditions, and issues like child labor, discrimination, social protection have been ignored.
Investigation of steady-state tokamak issues by long pulse experiments on Tore Supra

The main results of the Tore Supra experimental programme in the years 2007–2008 are reported. They document significant progress achieved in the domain of steady-state tokamak research, as well as in more general issues relevant for ITER and for fusion physics research. Three areas are covered: ITER relevant technology developments and tests in a real machine environment, tokamak operational issues for high power and long pulses, and fusion plasma physics. Results presented in this paper include test and validation of a new, load-resilient concept of ion cycotron resonance heating antenna and of an inspection robot operated under ultra-high vacuum and high temperature conditions; an extensive experimental campaign (5 h of plasma) aiming at deuterium inventory and carbon migration studies; real-time control of sawteeth by electron cyclotron current drive in the presence of fast ion tails; ECRH-assisted plasma start-up studies; dimensionless scalings of transport and turbulence; transport experiments using active perturbation methods; resistive and fast-particle driven MHD studies. The potential role of Tore Supra in the worldwide fusion programme before the start of ITER operation is also discussed.
Obesity, Metabolic Syndrome and Risk of Atrial Fibrillation: A Swedish, Prospective Cohort Study

Aim We aimed to investigate whether different measures of obesity could similarly predict atrial fibrillation, and whether the atrial fibrillation risk associated with obesity is dependent on presence of metabolic syndrome. Material and Methods We performed our study in a population-based longitudinal cardiovascular study, comprising 1 924 men and 2 097 women, aged 60 years, from Stockholm. Body mass index, waist circumference, sagittal abdominal diameter and components of metabolic syndrome (systolic- and diastolic blood pressure, fasting glucose, triglycerides, high-density lipoprotein-cholesterol) were recorded at baseline. Participants were classified by their body mass index (normal weight, overweight or obese), waist circumference (normal, semi-elevated or elevated), and according to presence of metabolic syndrome. Atrial fibrillation risk was estimated by Cox proportional hazards regression models, adjusted for common atrial fibrillation risk factors, expressed as HR and 95% CI. Results During a mean follow-up of 13.6 years, 285 incident atrial fibrillation cases were recorded. One standard deviation increment of each obesity measure was associated with increased atrial fibrillation risk as: body mass index 1.25 (1.12 – 1.40), waist circumference 1.35 (1.19 – 1.54) and sagittal abdominal diameter 1.28 (1.14 – 1.44). Compared to normal weight subjects without metabolic syndrome, increased atrial fibrillation risk was noted for overweight subjects with metabolic syndrome, 1.67 (1.16 – 2.41), obese subjects without metabolic syndrome, 1.75 (1.11 – 2.74) and obese subjects with metabolic syndrome, 1.92 (1.34 – 2.74). Compared to subjects with normal waist circumference without metabolic syndrome, subjects with elevated waist circumference and metabolic syndrome suffered increased atrial fibrillation risk, 2.03 (1.44 – 2.87). Conclusions Body mass index, waist circumference and sagittal abdominal diameter could similarly predict atrial fibrillation. Obesity was associated with an increased atrial fibrillation risk regardless of metabolic syndrome, whereas overweight and elevated waist circumference was associated with increased atrial fibrillation risk only if metabolic syndrome was present.
Comparison of Long-term Memory Function in Elderly Across Mind Activity and Diabetes Mellitus-type 2

Objectives: While Diabetes Mellitus (DM) affects cognitive functions and the Long Term Memory (LTM), several different strategies are designed to control harmful consequences of DM. This study is investigating whether having Mind Activity (MA) can make any difference in LTM function of individuals with DM. Design: The participants (n=80) were classified in 4 groups based on having DM or not and having MA or not. Methods: The LTM and MA were assessed respectively by the word-list of Tulving and Pearlstone, and a selfreport form. The BG concentrations were measured in vitro. Results: The results showed a significant negative correlation between BG concentrations and LTM scores in group with DM. The LTM function is significantly lower in group with DM and no-Mind Activity (nMA) respectively than the group with no-Diabetes Mellitus (nDM) and with MA. Also the LTM scores of the groups with nDM&MA, nDM&MA, DM&MA, nDM&MA, nDM&nMA and nDM&MA which were respectively higher than those of the groups with nDM&nMA, DM&MA, DM&nMA, DM&nMA, DM&nMA and DM&MA were statistically significant. Conclusions: The weaker BG control in patients with DM, the higher LTM dysfunction; and LTM function is in close relationship with DM (negatively) and MA (positively). Patients with DM and individuals with nDM who have their minds active in elderly, may less likely confront LTM dysfunction than matched groups who do not have active minds. DOI : 10.14302/Iissn.2474-9273.jbtm-16-1308 Corresponding Author: Sara Shabani, Department of Psychology, Science and Research Branch, Islamic Azad University, Tehran, Iran, E-mail: sara.shabani@srbiau.ac. ir, Tel: +98 21 22431813 Cellphone: +98 918 3073928, Fax: +98 21 22439009.
IL1RN and KRT13 Expression in Bladder Cancer: Association with Pathologic Characteristics and Smoking Status

Purpose. To validate microarray data on cytokeratin 13 (KRT13) and interleukin-1 receptor antagonist (IL1RN) expression in urothelial carcinoma of the urinary bladder (UCB) and to correlate our findings with pathologic characteristics and tobacco smoking. Methods. UCB tissue samples (n = 109) and control samples (n = 14) were obtained from transurethral resection and radical cystectomy specimens. Immunohistochemical staining of KRT13 and IL1RN was performed and semiquantitative expression scores were assessed. Smoking status was evaluated using a standardized questionnaire. Expression scores were correlated with pathologic characteristics (tumor stage and grade) and with smoking status. Results. Loss of KRT13 and IL1RN expression was observed in UCB tissue samples when compared to controls (P = 0.007, P = 0.008) in which KRT13 and IL1RN expression were high. IL1RN expression was significantly reduced in muscle-invasive tumors (P = 0.003). In tissue samples of current smokers, a significant downregulation of IL1RN was found when compared to never smokers (P = 0.013). Conclusion. Decreased expressions of KRT13 and IL1RN are common features of UCB and are associated with aggressive disease. Tobacco smoking may enhance the loss of IL1RN, indicating an overweight of proinflammatory mediators involved in UCB progression. Further validation of the influence of smoking on IL1RN expression is warranted.
Planning Your SQL-on-Hadoop Deployment Using a Low-Cost Simulation-Based Approach

The term "SQL-on-Hadoop" has recently gained significant traction [19]. Impala represents a new emerging class of SQL-on-Hadoop systems that exploit a shared-nothing parallel database architecture over Hadoop. Impala was designed to close the gap of near real time data analytics on Hadoop stack and it has shown itself to be significantly more efficient than other SQL-on-Hadoop solutions [13]. However, it is not a trivial task to leverage Impala for handling queries with different business demands [12]. Improperly deploying an Impala cluster may not give you the expected performance you want. In this paper, we propose a novel Impala simulation framework to help IT professionals to understand its performance behavior. This would simplify the deployment planning work required to enable big data analytics on SQL-on-Hadoop systems. An Impala simulator models the behavior of a complete software stack and simulates the activities of cluster components such as storage, network, processors and memory. Moreover, the accuracy of the simulation remain high in response to both software configuration and hardware changes, it reflects the expected scaling trend with low cost overhead and fast simulation speed. The Impala simulator has been validated against various S/W and H/W configurations, using the well-known TPC-DS benchmark [15], and the simulation results are valid and expected. A use case is provided to show how one would use the simulator to solve their performance and deployment issues.
A New Technique to Assist Epidural Needle Placement: Fiberoptic-guided Insertion Using Two Wavelengths

Background:Up to 10% of epidurals fail due to incorrect catheter placement. We describe a novel optical method to assist epidural catheter insertion in a porcine model. Methods:Optical emissions were tested on ex vivo tissues from porcine paravertebral tissues to identify optical reflective spectra. The wavelengths of 650 and 532 nm differentiated epidural space from the ligamentum flavum. We then used a hollow stylet that contained optical fibers to place epidural needles in anesthetized pigs. Real-time data were displayed on an oscilloscope and stored for analysis. A total of 50 punctures were done in four laboratory pigs. Data were expressed as mean ± SD. Results:Paired t test shows significant optical differences between the epidural space and the ligamentum flavum at both 650 nm (P < 0.001) and 532 nm (P = 0.014). Mean magnitudes for 650 nm, 532 nm, and their ratio were 3.565 ± 0.194, 2.542 ± 0.145, and 0.958 ± 0.172 at epidural space and 3.842 ± 0.191, 2.563 ± 0.131, and 1.228 ± 0.244 at ligamentum flavum, respectively. There were no differences in the optical characteristics of the ligamentum flavum and epidural space at different levels in the lumbar and thoracic region (two-way ANOVA P > 0.05). Conclusions:This is the first study to introduce a new optical method to localize epidural space in a porcine model. Epidural space could be identified by the changes in the reflective pattern of light emitted at 650 nm, which were specific for the ligamentum flavum and dural tissue. Real-time optical information successfully guided a modified Tuohy needle into the epidural space.