Miracle-dz/UniFAR-FTUs huggingface dataset:
Inhibition of p130cas tyrosine phosphorylation by calyculin A

P130cas is a dominant tyrosine phosphorylated protein in v‐src‐and v‐crk‐transformed cells. Tyrosine phosphorylation also occurs in response to integrin‐mediated cell adhesion. P130cas has a unique structure with multiple SH2 and SH3 binding sites, which makes it a candidate docking protein that might be involved in several signal transduction pathways. Little is known about how p130cas itself is regulated. In this report we present evidence that tyrosine phosphorylated p130cas was rapidly dephosphorylated in several lymphatic cell lines after treatment with calyculin A, a serine/ threonine phosphatase inhibitor. A similar result was obtained with okadaic acid, but higher concentrations and longer incubation times were required. Constitutive phosphorylation as well as receptor‐cross linking‐induced p130cas phosphorylation was inhibited. Furthermore, the p130cas‐Crk association was disrupted by treatment of cells with calyculin A. However, the p130cas‐Lyn association was not affected. These results suggest that calyculin A specifically affects SH2 domain‐mediated protein‐protein interactions and that Lyn does not bind to a susceptible SH2 domain. Furthermore, the data presented is consistent with the existence of a calyculin A‐sensitive phosphatase or tyrosine kinase that may be a critical regulator of p130cas tyrosine phosphorylation. J. Leukoc. Biol. 63: 631–635; 1998.
Leadership and Information Processing

There is a large body of research showing that people selectively prefer information that supports their decisions and opinions, and avoid conflicting information (selective information processing). Three studies were conducted to examine how the different leadership styles of supervisors influence subordinates’ selective information processing (i.e., the evaluation, seeking, and conveying of information). Studies 1 and 2 indicate that students in the role of subordinates who were exposed to transformational supervisors process information in a more balanced way than do those who were led by a transactional supervisor. Study 3 was carried out with professionals and showed that transformational leadership was negatively correlated with selective information seeking and conveying. This finding was mediated by the experience of positive emotions. Transactional leadership, by contrast, was not significantly associated with selective information processing. Theoretical and practical implications are discussed.
The Greatest Gift? Happiness, Governance and Psychology

Both in the UK and internationally, governments are setting out to measure well-being, life satisfaction and happiness. Whilst this might seem to offer opportunities for psychology, their chosen method – self-report questionnaires – is problematic. Happiness questionnaires are troubled by problems of definition, introspection, memory and insight; their population-level summation is grossly inaccurate as a representation of everyday emotional experience; and both their reliability and their validity might be better accounted for as products of their ability to model, rather than to measure, psychological processes. Psychology therefore runs the risk of discrediting itself if it becomes too closely associated with these initiatives.
Mobile Collaboration Learning Technique on Students in Developing Nations

 Abstract — New and more powerful communications technologies continue to emerge at a rapid pace and their uses in education are widespread and the impact remarkable in the developing societies. This study investigates Mobile Collaboration Learning Technique (MCLT) on learners’ outcome among students in tertiary institutions of developing nations (a case of Nigeria students). It examines the significance of retention achievement scores of students taught using mobile collaboration and conventional method. The sample consisted of 120 students using Stratified random sampling method. Five research questions and hypotheses were formulated, and tested at 0.05 level of significance. A student achievement test (SAT) was made of 40 items of multiple-choice objective type, developed and validated for data collection by professionals. The SAT was administered to students as pre-test and post-test. The data were analyzed using t-test statistic to test the hypotheses. The result indicated that students taught using MCLT performed significantly better than their counterparts using the conventional method of instruction. Also, there was no significant difference in the post-test performance scores of male and female students taught using MCLT. Based on the findings, the following submissions was made that: Mobile collaboration system be encouraged in the institutions to boost knowledge sharing among learners, workshop and training should be organized to train teachers on the use of this technique, schools and government should consistently align curriculum standard to trends of technological dictates and formulate policies and procedures towards responsible use of MCLT.
Semi-Supervised Cross-Media Feature Learning With Unified Patch Graph Regularization

With the rapid growth of multimedia data such as text, image, video, audio, and 3-D model, cross-media retrieval has become increasingly important, because users can retrieve the results with various types of media by submitting a query of any media type. Comparing with single-media retrieval such as image retrieval and text retrieval, cross-media retrieval is better because it provides the retrieval results with all kinds of media at the same time. In this paper, we focus on how to learn cross-media features for different media types, which is a key challenge for cross-media retrieval. Existing methods either model different media types separately or only exploit the labeled multimedia data. Actually, the data from different media types with the same semantic category are complementary to each other, and jointly modeling them is able to improve the accuracy of cross-media retrieval. In addition, although the labeled data are accurate, they require a lot of human labor and thus are very scarce. To address the above problems, we propose a semi-supervised cross-media feature learning algorithm with unified patch graph regularization (S2UPG). Our motivation and contribution mainly lie in the following three aspects. First, existing methods only model different media types in different graphs, while we employ one joint graph to simultaneously model all the media types. The joint graph is able to fully exploit the semantic correlations among various media types, which are complementary to provide the rich hint for cross-media correlation. Second, existing methods only consider the original media instances (such as images, videos, texts, audios, and 3-D models) but ignore their patches, while we make full use of both the media instances and their patches in one graph. Cross-media patches could emphasize the important parts and make cross-media correlations more precise. Third, traditional semi-supervised learning methods only exploit single-media unlabeled instances, while our approach fully exploits cross-media unlabeled instances and their patches, which can increase the diversity of training data and boost the accuracy of cross-media retrieval. Comparing with the current state-of-the-art methods on three datasets, including the challenging XMedia dataset with five media types, the comprehensive experimental results show that our proposed approach performs better.
Locating faults by the traveling waves they launch

Faults on overhead transmission lines cause transients that travel at the speed of light and propagate along the power line as traveling waves (TWs). This paper provides an overview of TWs and TW fault locators. It explains the physics, reviews the theory of TWs, explains the foundations of various types of TW fault locators, and provides an in-depth discussion on a number of TW fault locating implementation challenges. Finally, it discusses integration of TW fault locating in microprocessor-based relays and presents Bonneville Power Administration's (BPA's) field experience using these relays.
Interleukin 1β Induces Type II-secreted Phospholipase A2 Gene in Vascular Smooth Muscle Cells by a Nuclear Factor κB and Peroxisome Proliferator-activated Receptor-mediated Process*

Type II-secreted phospholipase A2 (type II-sPLA2) is expressed in smooth muscle cells during atherosclerosis or in response to interleukin-1β. The present study shows that the induction of type II-sPLA2gene by interleukin-1β requires activation of the NFκB pathway and cytosolic PLA2/PPARγ pathway, which are both necessary to achieve the transcriptional process. Interleukin-1β induced type II-sPLA2 gene dose- and time-dependently and increased the binding of NFκB to a specific site of type II-sPLA2 promoter. This effect was abolished by proteinase inhibitors that block the proteasome machinery and NFκB nuclear translocation. Type II-sPLA2 induction was also obtained by free arachidonic acid and was blocked by either AACOCF3, a specific cytosolic-PLA2 inhibitor, PD98059, a mitogen-activated protein kinase kinase inhibitor which prevents cytosolic PLA2 activation, or nordihydroguaiaretic acid, a lipoxygenase inhibitor, but not by the cyclooxygenase inhibitor indomethacin, suggesting a role for a lipoxygenase product. Type II-sPLA2 induction was obtained after treatment of the cells by 15-deoxy-Δ12,14-dehydroprostaglandin J2, carbaprostacyclin, and 9-hydroxyoctadecadienoic acid, which are ligands of peroxisome proliferator-activated receptor (PPAR) γ, whereas PPARα ligands were ineffective. Interleukin-1β as well as PPARγ-ligands stimulated the activity of a reporter gene containing PPARγ-binding sites in its promoter. Binding of both NFκB and PPARγ to their promoter is required to stimulate the transcriptional process since inhibitors of each class block interleukin-1β-induced type II-sPLA2 gene activation. We therefore suggest that NFκB and PPARγ cooperate at the enhanceosome-coactivator level to turn on transcription of the proinflammatory type II-sPLA2 gene.
‘Mobile transmigrants’ or ‘unsettled returnees’? myth of return and permanent resettlement among Senegalese migrants

The importance gained by transnationalism and growing attention for the development potential of migration have recently brought forward a new concern for the issue of return migration. Within this framework, return to the home country is understood as having an increasingly less permanent nature. Transnational movement itself is conceived as a form of return, and the debate on the migration–development nexus considers circulation to foster development as it enhances the flow of financial, social, and cultural capital to countries of origin. Seldom, however, has research taken into account the view of migrants themselves. What are their perceptions of transnationalism and return? Based on ethnographic research conducted among Senegalese migrants in the home country and in Italy, this paper demonstrates the existence, the logics, and functioning of a transmigrant movement made of people who are regular ‘comers and goers’ between Africa and Europe. I show, however, that in the view of these largely unskilled migrants, successful return is still associated with permanent return. This desire for definitive resettlement in the home society must nonetheless be compromised with aspirations for economic advancement and family obligations. Continually delayed, permanent return acquires the status of a myth. Copyright © 2010 John Wiley & Sons, Ltd.
Effects of varying type of exertion on children's attention capacity.

PURPOSE The aim of this investigation was to examine the potential influence of varying types of exertion on immediate attentional performance on 138 primary school boys and girls. METHODS Subjects performed three different types of exertion [cognitive exertion (school curricular lesson), physical exertion (traditional physical education lesson), and mixed cognitive and physical exertion (coordinative physical education lesson)] at the same time of the school day for 3 wk. Before and immediately after each exertion session, subjects were administered the d2 Test of Attention. RESULTS Results showed that participants' attentional performances were significantly affected by exertion type (cognitive exertion vs physical exertion vs mixed cognitive and physical exertion; P < 0.05), by intervention (before vs after; P < 0.05), and by exertion type × intervention interactions (P < 0.01). CONCLUSIONS Our findings suggest that varying types of exertion have different beneficial influences on schoolchildren's immediate cognitive performance.
A NEW 24 μm PHASE CURVE FOR υ ANDROMEDAE b

We report the detection of 24 μm variations from the planet-hosting υ Andromedae system consistent with the orbital periodicity of the system's innermost planet, υ And b. We find a peak-to-valley phase curve amplitude of 0.00130 times the mean system flux. Using a simple model with two hemispheres of constant surface brightness and assuming a planetary radius of 1.3 RJ give a planetary temperature contrast of ≳900 K and an orbital inclination of ≳28°. We further report the largest phase offset yet observed for an extrasolar planet: the flux maximum occurs ∼80° before phase 0.5. Such a large phase offset is difficult to reconcile with most current atmospheric circulation models. We improve on earlier observations of this system in several important ways: (1) observations of a flux calibrator star demonstrate the MIPS detector is stable to 10−4 on long timescales, (2) we note that the background light varies systematically due to spacecraft operations, precluding use of this background as a flux calibrator (stellar flux measured above the background is not similarly affected), and (3) we calibrate for flux variability correlated with motion of the star on the MIPS detector. A reanalysis of our earlier observations of this system is consistent with our new result.
Towards an explanation of phonetic differentiation in masculine and feminine personal names

Recent research has identified characteristic differences between the phonetic structures of names and of ordinary nouns, with particularly distinctive patterns being exhibited by feminine personal names. No explanation has yet been found. This paper suggests that the solution lies not in the English sound system, as has previously been assumed, but in differences between the linguistic origins of the various types of material.
Generating French with a Reversible Unification Grammar

O. Intr~cluction In this paper, we describe the linguistic solutions to some of the problems encountered in writing a reversible French grammar. This grammar is primarily intended to be one of the components of a machine translation system built using ELU, 1 an enhanced PATR-II style unification grammar linguistic environment based on the LID system described in Johnson and Rosner (1989), but it is also part of our more general experimentation with fully reversible grammars. The requirement that it be reversible imposes a stringent criterion of linguistic adequacy on a grammar, siuce it is not allowed to overgenerate while it must at the same time provide a large coverage for analysis (Dymetman and IsabeUe (1988)). Formally, grammars that are fully reversible must be completely declarative, since no reierence can be made in the grammar rules to the process (analyzer or synthesizer) which will use them. The unification formalism makes itt possible to write such grammar statements, because due to the associativity and commutativity of the unitication operation, the result of unifying feature structures is independent of the order in which they are unitied (Appelt (1989)). Writing reversible grammars, however, presents problems which do not arise in the traditional grammars used for either analysis or generation. In addition, the progress accomplished recently in building generators for unification grammars has already revealed some of the problems posed by unificationbased reversible grammars. 2 As shown by Russell et al. (1990), even though the grammar rules do not refer to the generation process, the generation algorithm imposes particular constraints on the grammar formalism. 3 This paper concentrates particularly on the problems encountered in the generation of French, specifically in the analysis to be given to clitics.
An Aspirational Framework for Strategic Human Resource Management

AbstractThe field of strategic human resource management (HRM) has a long and rich tradition. As a prelude to our description of the field's history, we provide an expansive definition of strategic HRM scholarship and offer an aspirational framework for strategic HRM scholarship that captures the multidisciplinary nature of the field. We then systematically review and critique three decades of strategic HRM theory and research, paying particular attention to the value of HRM systems as management tools for influencing a wide variety of outcomes of concern to internal (employees and their managers) and external (owners, customers, society, other organizations) stakeholders. In support of continued advancement of the empirical knowledge base of strategic HRM, we encourage new research that embraces systems thinking, more fully addresses the concerns of multiple stakeholders, and strives for greater practical usefulness by addressing significant problems such as managing innovation and environmental sustaina.
Transdifferentiation of Small Cell Carcinoma of the Urinary Bladder from Urothelial Carcinoma after Transurethral Resection of a Bladder Tumor, Intravesical Bacillus Calmette-Guerin Instillation, and Chemotherapy: A Case Report

A 73-year-old male underwent transurethral resection of a bladder tumor in August 2010 and April 2011. Pathological examination revealed urothelial carcinoma. After the surgery, chemotherapy and intravesical Bacillus Calmette-Guerin instillation were performed. In September 2014, he once again underwent transurethral resection of the bladder tumor for recurrence, and was again diagnosed with urothelial carcinoma, pT2, by pathological examination. After neoadjuvant chemotherapy, radical cystectomy for tumor recurrence was performed. Pathological examination at this time revealed small cell carcinoma, pT3N0. It is rare for urothelial carcinoma to change to small cell carcinoma, and the mechanism and cause of this change are still unknown. In this case report, we discuss what causes small cell carcinoma of the urinary bladder and review the literature regarding its origin.
An adaptive neighborhood taboo search on GPU for Hardware/Software Co-design

Hardware/software partitioning is an essential step in Hardware/Software Co-design. This paper presents a GPU-accelerated adaptive neighborhood taboo search algorithm(GPU-accelerated ANTS) to solve the problem. Firstly, a pre-GPU version of ANTS is presented to test our idea, in which both the number of feasible candidates in neighborhood and the length of taboo list can be adaptively adjusted. Secondly, a GPU-accelerated version combined with the two merits from pre-GPU version is presented. Furthermore, in order to fully leverage the power of GPU, the special consideration for the optimization strategies and implementation details on GPU are explored for our GPU- accelerated ANTS algorithm. Finally, enough number of experiments show that our GPU-accelerated ANTS method outperforms state-of-the-art work of taboo search for the HW/SW partitioning in both quality and speed under mid/low range GPU platform.
Right and left ventricular geometry and myocyte contractile processes with dilated cardiomyopathy: myocyte growth and beta-adrenergic responsiveness.

OBJECTIVES Comparison of the effects of supraventricular tachycardia-induced dilated cardiomyopathy on left and right ventricular isolated myocyte geometry and function. BACKGROUND Chronic ventricular tachycardia and supraventricular tachycardia cause left ventricular dilation and dysfunction in humans. However, it is unknown whether supraventricular tachycardia-induced dilated cardiomyopathy is a homogenous process for both the left and right ventricles. METHODS Dilated cardiomyopathy was induced by rapid atrial pacing (240 beats/min, 3 weeks) in 5 pigs. Five age- and weight-matched pigs served as controls. Ventricular mass was measured, myocyte dimensions were obtained, and isolated right and left ventricular myocyte contractile performance was evaluated at baseline and after beta-adrenergic receptor stimulation. RESULTS With the development of dilated cardiomyopathy, there was no change in left ventricular mass. In contrast, right ventricular mass was increased, as was right ventricular myocyte cross-sectional area. In the control group, baseline right ventricular myocyte contractile function was increased compared to left ventricular myocytes. beta-adrenergic receptor stimulation increased myocyte contractile function in both left and right ventricular myocytes. With supraventricular tachycardia-induced cardiomyopathy, both left and right ventricular myocyte contractile function and beta-adrenergic responsiveness were reduced. CONCLUSIONS This study demonstrated differences in left and right ventricular myocyte growth with supraventricular tachycardia-induced dilated cardiomyopathy and this differential growth response was associated with changes in contractile performance. Thus, in this model of cardiomyopathic disease, left and right ventricular growth and changes in contractile performance are not a homogenous process.
The Effect of Reading While Listening on TOEFL Gains

The present study investigated the effect of Reading While Listening (RWL) on overall English comprehension among a group of EFL students. It was hypothesized that the amount of RWL would be correlated with gains on a standardized test of English (TOEFL ITP). The current study was based on the results of previous studies with extensive reading (ER), the idea that L2 readers acquire and access lexical items in a similar fashion to L1 readers, and that development of such item-specific phonemic awareness would be significantly aided by an audio accompaniment to silent reading. A total of 162 ESL learners participated in the study. After two semesters of treatment, results demonstrated a statistically significant gain in pre-TOEFL ITP scores. A multiple regression analysis was then performed to determine the effect of quantity of RWL on TOEFL gain scores. Results indicated the amount of RWL was a significant predictor of TOEFL ITP gain scores. Subsequent theoretical and pedagogical implications are discussed.
Semi-Citizenship in Democratic Politics

In every democratic polity there exist individuals and groups who hold some but not all of the essential elements of citizenship. Scholars who study citizenship routinely reach for shared concepts and language to identify forms of political membership held by migrants, children, the disabled, and other groups of individuals who, for various reasons, are neither full citizens nor non-citizens.This book introduces the concept of semi-citizenship as a means of dramatically advancing debates about individuals who hold some, but not all, elements of full democratic citizenship. By analytically classifying the rights of citizenship and their various combinations, scholars can typologize semi-citizens and produce comparisons of different kinds of semi-citizenships and of semi-citizenships in different states. The book uses theoretical analysis, historical examples, and contemporary cases of semi-citizenship to illustrate how normative and governmental doctrines of citizenship converge and conflict, making semi-citizenship an enduring and inevitable part of democratic politics.