Miracle-dz/UniFAR-FTUs huggingface dataset:
Modern Electrochemistry in Nanobiology and Sensorics

protein (dimerisation), and covalent linkage to the nitrogen atom of a neighboring amino acid residue to form a sulfenamide. These modifications can be reversed by cellular reductants such as a glutathione (GSH). Sulfenic acid can also be irreversibly oxidized further to sulfinic or sulfonic acid species. to [38]). Glutathione peroxidases (GPx) oxidize GSH to GSSG in response to peroxides, including H 2 O 2 and lipid hydroperoxides (LOOx), thus increasing the gluta‐ thione redox potential ( E GSH ). Abbreviations: LOx, reduced lipid oxide; SC – , reduced selenocyteine; SCOH, oxidized sele‐ nocyteine; SCSG, glutathionylated selenocysteine. In response to the increase in GSSG, one of the engineered vicinal cysteines of roGFP becomes S -glutathionylated by glutaredoxin (Grx). Glutathionylation in turn causes disulfide bond formation and alteration of the spectral properties of the GFP fluorophore. In the reductive pathway, Grx catalyzes the reduction of roGFP disulfide bonds through deglutathionylation as GSSG levels decrease and normal levels of GSH are reestablished by glutathione reductase (GlRed), at the expense of NADPH, causing a renormalization of E GSH . Glucose and the pentose-phosphate pathway (PPPath) create NADPH, which is used by GlRed to reduce GSSG to GSH.
Online Speech Dereverberation Using Kalman Filter and EM Algorithm

Speech signals recorded in a room are commonly degraded by reverberation. In most cases, both the speech signal and the acoustic system of the room are unknown and time-varying. In this paper, a scenario with a single desired sound source and slowly time-varying and spatially-white noise is considered, and a multi-microphone algorithm that simultaneously estimates the clean speech signal and the time-varying acoustic system is proposed. The recursive expectation-maximization scheme is employed to obtain both the clean speech signal and the acoustic system in an online manner. In the expectation step, the Kalman filter is applied to extract a new sample of the clean signal, and in the maximization step, the system estimate is updated according to the output of the Kalman filter. Experimental results show that the proposed method is able to significantly reduce reverberation and increase the speech quality. Moreover, the tracking ability of the algorithm was validated in practical scenarios using human speakers moving in a natural manner.
RGB Color Model Based the Fire Detection Algorithm in Video Sequences on Wireless Sensor Network

Since the fire causes serious disasters, fire detection has been an important study to protect human life. Based on the deficiencies of existing fire detection on real-time and monitoring accuracy, the wireless sensor network technique for fire detection was introduced and needed. In this paper, we proposed the fire detection algorithm in video sequences on wireless sensor network. The proposed fire detection algorithm processes visual information acquired through static camera that lets us incorporate the algorithm to CCTV surveillance system, and therefore does not require an additional expanses on conventional fire sensors. Fire detection method based on motion information, any input image, is compared to background in order to identify foreground. Background is statistically modeled by mixture of Gaussians. To detect the foreground of video sequences, the proposed color detection algorithm was performed in RGB space. The procedure of algorithm eliminates all objects that do not fulfill color requirements without fire-like objects. And the change map and blob's area are computed, change map shows temporal variation of pixel between two consecutive binary frames, and percentage area increase or decrease characterizes a fire property for swinging.
Bubble dynamics during capillary-fed nucleate boiling in porous media

Boiling from structured surfaces offers an effective heat transfer enhancement strategy. While there have been attempts to develop models to predict the boiling heat transfer coefficient from sintered screen meshes or sintered particles, less is known about the detailed mechanisms of bubble growth and departure in a porous medium. In this work, we study the growth of a vapor bubble in a micro-scale porous medium in which bubble growth is impeded by the drag offered by the porous medium. We use a volume-of-fluid model to track the liquid-vapor interface during bubble growth. Isotropic and anisotropic arrangements of sintered particles are modeled as uniform particles aligned in hexagonal and square-packed arrangements. A porosity range of 25%-75% is considered, while the particle diameter and wick thickness are held at 200 μm and 1 mm, respectively. The growth of a water vapor bubble nucleating at the interface between the porous medium and the substrate at a wall superheat of 5 K is investigated. Uniform bubble departure, present during the pool boiling of water, is not observed; instead, vapor columns are formed in the porous medium. A moderate wick porosity (50-70%) is found to assist the formation of vertical vapor columns in the wick pores. In contrast, laterally distributed vapor structures form at small porosities (<;50%). Based on the observed vapor column structures in the wick pores, an approximate mathematical model is proposed to optimize the wick thickness for maximum boiling performance. A wick thickness-to-particle diameter ratio in the range of 4 to 5 is found to optimize the heat transfer performance during boiling.
The Effectiveness of Postoperative Early Ostium Cleaning in Transcanalicular Diode Laser–Assisted Dacryocystorhinostomy

Purpose: To search the effectiveness of postoperative first week ostium cleaning in transcanalicular diode laser–assisted dacryocystorhinostomy (TDL-DCR). Materials and Methods: A total of 123 eyes of 123 patients with acquired dacryostenosis who had surgery were retrospectively evaluated. Diode laser was used in all patients. All patients were operated under local anesthesia by a single surgeon. Intranasal endoscopic cleaning of the ostium by surgical suction under local anesthesia was performed as an extra job in the postoperative first week visit. Results: Mean age of the patients was 55 (range, 41–78 years) years. Mean follow up was 13.4 months. Successful outcomes were achieved in 117 of 123 (95.1%) patients. Reoperation was performed in 6 patients with restenosis and were free of symptoms in 1-year follow up. Conclusion: Postoperative first week cleaning of the nasal ostium by surgical suction with the aiding of nasal endoscopy is a very effective method increasing the success rate of TDL-DCR.
An I-vector Based Approach to Compact Multi-Granularity Topic Spaces Representation of Textual Documents

Various studies highlighted that topicbased approaches give a powerful spoken content representation of documents. Nonetheless, these documents may contain more than one main theme, and their automatic transcription inevitably contains errors. In this study, we propose an original and promising framework based on a compact representation of a textual document, to solve issues related to topic space granularity. Firstly, various topic spaces are estimated with different numbers of classes from a Latent Dirichlet Allocation. Then, this multiple topic space representation is compacted into an elementary segment, calledc-vector, originally developed in the context of speaker recognition. Experiments are conducted on the DECODA corpus of conversations. Results show the effectiveness of the proposed multi-view compact representation paradigm. Our identification system reaches an accuracy of 85%, with a significant gain of 9 points compared to the baseline (best single topic space configuration).
Tunneled hemodialysis catheters: use of a silver-coated catheter for prevention of infection--a randomized study.

PURPOSE To determine whether silver-coated tunneled hemodialysis catheters reduce infection and to determine the frequency of central venous thrombosis and stenosis with percutaneous placement of right internal jugular vein dialysis catheters by interventional radiologists. MATERIALS AND METHODS Ninety-one patients were randomly assigned to a treatment (silver-coated catheter; n = 47) or control (identical catheter without silver coating; n = 44) arm. Baseline venography was performed. Catheter tips were cultured and venography was repeated at catheter removal. RESULTS Mean duration of catheter placement was 92 days. Infection occurred in 11 patients (five in the treatment group, six in the control group). Tip cultures in 15 patients (eight treatment, seven control) were positive without clinical infection. Infection and colonization rates were slightly but not significantly higher in the treatment group than in the control group. Silver-coated catheters in two (4%) patients were removed due to reaction to the coating. Completion venograms (n = 72) showed new minor abnormalities in four (6%) patients and major abnormalities (stenosis, thrombosis) in three (4%) patients. Permanent venous abnormalities occurred in two (3%) patients. CONCLUSION Silver coating does not confer a benefit against clinical infection or colonization. Interventional radiologic placement of tunneled dialysis catheters yields a low frequency of permanent central venous thrombosis and stenosis.
Recent changes in the global and regional carbon cycle: analysis of first-order diagnostics

Abstract. We analyse global and regional changes in CO2 fluxes using two simple models, an airborne fraction of anthropogenic emissions and a linear relationship with CO2 concentrations. We show that both models are able to fit the non-anthropogenic (hereafter natural) flux over the length of the atmospheric concentration record. Analysis of the linear model (including its uncertainties) suggests no significant decrease in the response of the natural carbon cycle. Recent data points rather to an increase. We apply the same linear diagnostic to fluxes from atmospheric inversions. Flux responses show clear regional and seasonal patterns driven by terrestrial uptake in the northern summer. Ocean fluxes show little or no linear response. Terrestrial models show clear responses, agreeing globally with the inversion responses, however the spatial structure is quite different, with dominant responses in the tropics rather than the northern extratropics.
The Global Phosphoproteome of Chlamydomonas reinhardtii Reveals Complex Organellar Phosphorylation in the Flagella and Thylakoid Membrane *

Chlamydomonas reinhardtii is the most intensively-studied and well-developed model for investigation of a wide-range of microalgal processes ranging from basic development through understanding triacylglycerol production. Although proteomic technologies permit interrogation of these processes at the protein level and efforts to date indicate phosphorylation-based regulation of proteins in C. reinhardtii is essential for its underlying biology, characterization of the C. reinhardtii phosphoproteome has been limited. Herein, we report the richest exploration of the C. reinhardtii proteome to date. Complementary enrichment strategies were used to detect 4588 phosphoproteins distributed among every cellular component in C. reinhardtii. Additionally, we report 18,160 unique phosphopeptides at <1% false discovery rate, which comprise 15,862 unique phosphosites - 98% of which are novel. Given that an estimated 30% of proteins in a eukaryotic cell are subject to phosphorylation, we report the majority of the phosphoproteome (23%) of C. reinhardtii. Proteins in key biological pathways were phosphorylated, including photosynthesis, pigment production, carbon assimilation, glycolysis, and protein and carbohydrate metabolism, and it is noteworthy that hyperphosphorylation was observed in flagellar proteins. This rich data set is available via ProteomeXchange (ID: PXD000783) and will significantly enhance understanding of a range of regulatory mechanisms controlling a variety of cellular process and will serve as a critical resource for the microalgal community.
Coronary computed tomography angiography with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisition.

AIMS We evaluated the feasibility and image quality of a new scan mode for coronary computed tomography angiography (CTA) with an effective dose of less than 1 mSv. METHODS AND RESULTS In 50 consecutive patients (body weight <or= 100 kg, sinus rhythm <or=60 b.p.m. after pre-medication, coronary CTA was performed using a dual-source CT system with 2 x 128 x 0.6 mm collimation, 0.28 s rotation time, a pitch of 3.2 or 3.4, 100 kV tube voltage and current of 320 mA s. Data acquisition was prospectively triggered at 60% of the R-R interval and completed within one cardiac cycle. Image quality was evaluated using a four-point scale (1 = absence of any artefacts to 4 = uninterpretable). In all 50 patients, imaging was successful. Mean duration of data acquisition was 258 +/- 20 ms. Mean dose-length product was 62 +/- 5 mGy cm, the effective dose was 0.87 +/- 0.07 mSv (0.78-0.99 mSv). Of the 742 coronary artery segments, 94% had an image quality score of 1, 5.0% a score of 2, 0.9% a score of 3, and 4 segments (0.5%) were 'uninterpretable'. CONCLUSION In non-obese patients with a low and stable heart rate, prospectively ECG-triggered high-pitch spiral coronary CTA provides excellent image quality at a consistent dose below 1.0 mSv.
Chemokines and Their Receptors in Human Renal Allotransplantation

Background. Chemokines and their receptors play a critical role in leukocyte trafficking, and inhibition of select chemokines has been shown to attenuate kidney disease and allograft rejection in animal models. Therefore, we evaluated chemokine and chemokine receptor transcripts in human renal allograft biopsies, correlating transcript levels with clinical course and immunohistochemical analysis to relate chemokine expression to relevant clinical human disease phenotypes. Methods. Renal biopsies were grouped as postreperfusion (n=10), stable function (n=10), subclinical (n=10) or acute rejection (n=17), or calcineurin inhibitor nephrotoxicity (n=9) based on clinical presentation and histopathologic assessment. Using quantitative real-time polymerase chain reaction analysis, chemokine transcripts were assessed relative to transcript levels in preprocurement biopsies from live donor kidneys (n=15). Results. Transcripts from several inflammatory chemokines (CCL3, CCL5, CXCL9, CXCL10, and CXCL11) and chemokine receptors (CCR5, CCR7, and CXCR3) were significantly increased in allografts with subclinical and clinical acute rejection, indicating a strong polarization toward a T-helper 1 effector phenotype during rejection. These transcripts also distinguished acutely rejecting allografts from allografts with nonrejection causes of renal dysfunction. Biopsies from patients with stable function without histologic evidence of rejection had increased chemokine transcript levels that were qualitatively similar but quantitatively reduced compared with rejecting allografts. Conclusions. This comprehensive evaluation of chemokines and their receptors in human renal transplantation defines associations between chemokine expression and clinical phenotypes, may have diagnostic utility, and highlights relevant pathways for therapeutic intervention.
Evidence for circular permutation of the prophage genome of Bacillus subtilis bacteriophage phi 105

Analysis of DNA extracted from Bacillus subtilis lysogenic for bacteriophage phi 105 was performed by restriction endonuclease digestion and Southern hybridization using mature phi 105 DNA as a probe. The data revealed that the phi 105 prophage is circularly permuted. Digests using the enzymes EcoRI, SmaI, PstI, and HindIII localized the bacteriophage attachment site (att) to a region 63.4 to 65.7% from the left end of the mature bacteriophage genome. The phi 105 att site-containing SmaI C, PstI J, and HindIII L fragments were not present in digests of phi 105 prophage DNA. phi 105-homologous "junction" fragments were visualized by probing digests of prophage DNA with the purified PstI J fragment isolated from the mature bacteriophage genome. The excision of the phi 105 prophage was detected by observing the appearance of the mature PstI J fragment and the concomitant disappearance of a junction fragment during the course of prophage induction.
Occipitocervical fusion after resection of craniovertebral junction tumors.

OBJECT Surgical access to tumors at the craniovertebral junction (CVJ) requires extensive bone removal. Guidelines for the use of occipitocervical fusion (OCF) after resection of CVJ tumors have been based on anecdotal evidence. The authors performed a retrospective study of factors associated with the use of OCF in 46 patients with CVJ tumors. The findings were used to develop recommendations for use of OCF in such patients. METHODS The authors retrospectively reviewed the cases of 51 patients with CVJ tumors treated by their group between March 1991 and February 2004. Forty-six patients were available for follow up. Charts were reviewed to obtain data on demographic characteristics, presenting symptoms, and perioperative complications. Preoperative computerized tomography scans and magnetic resonance imaging studies were obtained in all patients. Occipitocervical fusion was performed in patients who had undergone a unilateral condyle resection in which 70% or more of the condyle was removed, a bilateral condyle resection with 50% removal, or C1-2 vertebral body destruction. Of the 46 patients, 16 had foramen magnum meningiomas, 17 had chordomas, one had a chondrosarcoma, two had Schwann cell tumors, two had glomus tumors, and eight had other types of tumors. Twenty-three (50%) of the 46 patients underwent OCF, including 15 of the 17 patients with chordomas (88%). None of the patients with meningiomas required fusion. Seventeen (71%) of the 24 patients presenting with neck pain preoperatively underwent OCF. CONCLUSIONS Patients presenting with neck pain had a 71% chance of undergoing OCF. Patients with chordomas and metastatic tumors were most likely to require OCF. One patient with a 50% unilateral condylar resection returned with OC instability for which OCF was required. Based on their clinical experience and published biomechanical studies, the authors recommend that OCF be performed when 50% or more of one condyle is resected.
Tumor deposits counted as positive lymph nodes in TNM staging for advanced colorectal cancer: a retrospective multicenter study

We investigated the possibility of counting tumor deposits (TDs) as positive lymph nodes (pLNs) in the pN category and evaluated its prognostic value for colorectal cancer (CRC) patients. A new pN category (npN category) was calculated using the numbers of pLNs plus TDs. The npN category included 4 tiers: npN1a (1 tumor node), npN1b (2-3 tumor nodes), npN2a (4-6 tumor nodes), and npN2b (≥7 tumor nodes). We identified 4,121 locally advanced CRC patients, including 717 (11.02%) cases with TDs. Univariate and multivariate analyses were performed to evaluate the disease-free and overall survival (DFS and OS) for npN and pN categories. Multivariate analysis showed that the npN and pN categories were both independent prognostic factors for DFS (HR 1.614, 95% CI 1.541 to 1.673; HR 1.604, 95% CI 1.533 to 1.679) and OS (HR 1.633, 95% CI 1.550 to 1.720; HR 1.470, 95% CI 1.410 to 1.532). However, the npN category was superior to the pN category by Harrell's C statistic. We conclude that it is thus feasible to consider TDs as positive lymph nodes in the pN category when evaluating the prognoses of CRC patients, and the npN category is potentially superior to the TNM (7th edition) pN category for predicting DFS and OS among advanced CRC patients.
Consumption of milk with added casein phosphopeptide-amorphous calcium phosphate remineralizes enamel subsurface lesions in situ.

BACKGROUND Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is an anticariogenic agent that is suitable to be added to foods. The aim of this double-blind, three-way crossover randomized study was to investigate the capacity of CPP-ACP, when added to bovine milk, to remineralize enamel subsurface lesions in situ. METHODS Ten subjects drank 100 mL of bovine milk containing no added CPP-ACP (control milk), 0.2% (w/v) CPP-ACP or 0.3% (w/v) CPP-ACP, for 30 seconds once daily for 15 days, whilst wearing removable appliances with attached slabs of enamel containing subsurface enamel lesions. After each treatment and a one-week washout period, subjects crossed over to another treatment and this was repeated until they had consumed each of the three milk products. At the completion of each treatment the enamel slabs were removed and remineralization was determined using microradiography. RESULTS The results demonstrated that all three milk samples remineralized enamel subsurface lesions in situ. However, the two milk samples containing added CPP-ACP each produced significantly greater remineralization than the control milk. CONCLUSIONS The remineralizing effect of CPP-ACP in milk was dose-dependent with milk containing 0.2% CPP-ACP and 0.3% CPP-ACP producing an increase in mineral content of 81% and 164%, respectively, relative to the control milk.
Asset Markets With Heterogeneous Information

This paper studies competitive equilibria of economies where assets are heterogeneous and traders have heterogeneous information about them. Markets are defined by a price and a procedure for clearing trades, and any asset can, in principle, be traded in any market. Buyers can use their information to impose acceptance rules which specify which assets they are willing to trade in each market. The set of markets where trade takes place is derived endogenously. The model can be applied to find conditions under which these economies feature fire sales, contagion, and flights to quality.
Origami: A 803-GOp/s/W Convolutional Network Accelerator

An ever-increasing number of computer vision and image/video processing challenges are being approached using deep convolutional neural networks, obtaining state-of-the-art results in object recognition and detection, semantic segmentation, action recognition, optical flow, and super resolution. Hardware acceleration of these algorithms is essential to adopt these improvements in embedded and mobile computer vision systems. We present a new architecture, design, and implementation, as well as the first reported silicon measurements of such an accelerator, outperforming previous work in terms of power, area, and I/O efficiency. The manufactured device provides up to 196 GOp/s on 3.09 $\text {mm}^{2}$ of silicon in UMC 65-nm technology and can achieve a power efficiency of 803 GOp/s/W. The massively reduced bandwidth requirements make it the first architecture scalable to TOp/s performance.
The radio halo in the merging cluster A3562

We present new VLA observations at 1.4 GHz confirming the presence of a radio halo at the centre of the cluster A3562, in the core of the Shapley Concentration. We also report a detailed multifrequency radio study of the head tail galaxy J1333–3141, which is completely embedded in the halo emission. The radio halo has an irregular shape, and a maximum linear size of ~620 kpc, which is among the smallest found in the literature. The source has a steep spectrum, i.e. $\alpha_{843~{\rm MHz}}^{1.4~{\rm GHz}} \sim 2$, and its total radio power, $P_{1.4~{\rm GHz}} \sim 2~\times10^{23}$ W Hz -1 , is the lowest known to date. The radio power of the halo and the X–ray parameters of the cluster, such as L X and kT , nicely fit the correlations found in the literature for the other halo clusters, extending them to low radio powers. We found that the total number of electrons injected in the cluster environment by the head–tail source is enough to feed the halo, if we assume that the galaxy has been radio active over a large fraction of its crossing time. We discuss possible origins of the radio halo in the light of the two–phase model (Brunetti et al. 2001) and propose that the observed scenario is the result of a young source at the beginning of the reacceleration phase.