Miracle-dz/UniFAR-FTUs huggingface dataset:
Peritoneal Defense Using Icodextrin Or Glucose for Daytime Dwell in Ccpd Patients

Objective To investigate peritoneal defense during icodextrin use in continuous cyclic peritoneal dialysis (CCPD). Design In an open, prospective, 2-year follow-up study, CCPD patients were randomized to either glucose (Glu) or icodextrin (Ico) for their long daytime dwell. Setting University hospital and teaching hospital. Patients Both established and patients new to CCPD were included. A life expectancy of more than 2 years, a stable clinical condition, and written informed consent were necessary before entry. Patients aged under 18 years, those who had peritonitis in the previous month, and women of childbearing potential, unless taking adequate contraceptive precautions, were excluded. Thirty-eight patients (19 Glu, 19 Ico) started the study. The median follow-up was 16 and 17 months for Glu and Ico respectively (range 0.5 – 25 months and 5 – 25 months, respectively). Outcome Measures Peritoneal defense characteristics and peritoneal dialysis-related infections were recorded every 3 months. Results Total peritoneal white cell count tended to decrease over time in both groups. After 1 year, absolute numbers and percentages of effluent peritoneal macrophages (PMΦs) were significantly higher in Ico than in Glu patients; this difference in the percentage persisted after 2 years. Percentage of mesothelial cells increased over time in Ico patients. The phagocytic capacity of PMΦs decreased over time, resulting in a borderline significant difference for coagulase-negative staphylococci (p = 0.05) and a significant difference for Escherichia coli (p < 0.05) phagocytosis in favor of Ico patients. PMΦ oxidative metabolism remained stable over time without a difference between the groups. PMΦ cytokine production and effluent opsonic capacity also remained stable over time. Finally, 16 peritonitis episodes in Glu and 14 in Ico patients occurred. Glucose patients had 37 and Ico patients 32 exit-site infections during the study. Conclusion CCPD patients using Ico did equally as well as Glu-treated patients with respect to clinical infections and most peritoneal defense characteristics. However, in a few peritoneal defense tests, Ico-treated patients did better.
Cognitive Behavioral Development in Children Following Maternal Postpartum Depression: A Review Article

Mothers’ constitute is a very important part of infants’ social environment and mediate their experience with the surrounding world. Postpartum depression, which is considered one of the most common and important psychiatric disorders, affects 10–15% of mothers, its causes are different. By investigating various sources, some effects of this disorder have been observed on the cognitive development of children, particularly among boys, such as language, intelligence quotient (IQ), and behavioral problems. Thus, it is imperative to study the effects of postpartum depression on children’s growth and development and to identify methods of reducing these effects. This review indicates that postpartum depression in mothers reduces children’s cognitive performance. The adverse effects of postpartum depression on children’s development seem to be mediated by the mother’s interpersonal behavior and the infant gender. The review of previous studies shows that postpartum depression reduces children’s cognitive performance by impairing maternal mental and behavioral care.
Detecting Feigning in Adolescents on the Personality Assessment Inventory—Adolescent Form

Abstract Much of the research on identifying feigning in psychological assessment has focused on adults with less attention to adolescents. The purpose of the present study is to expand the limited literature on detecting feigning in adolescents using the Personality Assessment Inventory – Adolescent. The study included 114 nonclinical adolescents (ages 15 to 18) recruited from high schools in the Midwest who were randomly assigned to experimental groups: honest nonclinical, uncoached feigning, and coached feigning. 50 randomly selected individuals with depression from the PAI-A clinical standardization sample were included as the honest clinical group. Sample demographics included a mean age of 16.64 years; 51.2% young men, 48.2% young women; 85.4% Caucasian, 6.7% African American, 5.5% Hispanic, and 2.4% Asian. 80% of feigning profiles reported clinical levels of depression. MANOVA results showed strong support for the Rogers Discriminant Function (RDF; d range = 1.85–2.05). The Negative Impression Management (NIM) scale also demonstrated promise (d range = 0.77–1.08), while the smallest effects for detecting feigning were found for the Malingering Index (d range = 0.58–0.70). The negative distortion indices showed good utility in differentiating between groups. Cut-scores and pragmatic implications are presented.
Comparing voice chat and text chat in a communication tool for interactive television

Talking during the course of a television program is something that has been done almost since the introduction of the television in the household, and is one of the most important social uses of television. Interactive television extends this concept beyond the family household, making it possible to talk with family and friends at remote households. This particular study looks at two modes of communication, more specifically voice chat and text chat, and what the advantages and disadvantages are of these systems when communicating while watching television. The results show that voice chat is considered more natural and direct, and makes it easier to keep on following the program. Text chat is more preferred by younger users and users having more experience with chatting on computers, and is therefore interesting to use in interactive services specifically aimed at youngsters. In both cases, our study shows that such systems should be carefully designed to divide attention between watching and communicating in such a way that distraction from the television program is minimized.
Small forwarding tables for fast routing lookups

For some time, the networking community has assumed that it is impossible to do IP routing lookups in software fast enough to support gigabit speeds. IP routing lookups must find the routing entry with the longest matching prefix, a task that has been thought to require hardware support at lookup frequencies of millions per second.We present a forwarding table data structure designed for quick routing lookups. Forwarding tables are small enough to fit in the cache of a conventional general purpose processor. With the table in cache, a 200 MHz Pentium Pro or a 333 MHz Alpha 21164 can perform a few million lookups per second. This means that it is feasible to do a full routing lookup for each IP packet at gigabit speeds without special hardware.The forwarding tables are very small, a large routing table with 40,000 routing entries can be compacted to a forwarding table of 150-160 Kbytes. A lookup typically requires less than 100 instructions on an Alpha, using eight memory references accessing a total of 14 bytes.
International Journal of Occupational Safety and Ergonomics Respiratory Impairment in Cotton-ginning Workers Exposed to Cotton Dust Respiratory Impairment in Cotton-ginning Workers Exposed to Cotton Dust

Taylor & Francis makes every effort to ensure the accuracy of all the information (the " Content ") contained in the publications on our platform. However, Taylor & Francis, our agents, and our licensors make no representations or warranties whatsoever as to the accuracy, completeness, or suitability for any purpose of the Content. Any opinions and views expressed in this publication are the opinions and views of the authors, and are not the views of or endorsed by Taylor & Francis. The accuracy of the Content should not be relied upon and should be independently verified with primary sources of information. Taylor and Francis shall not be liable for any losses, actions, claims, proceedings, demands, costs, expenses, damages, and other liabilities whatsoever or howsoever caused arising directly or indirectly in connection with, in relation to or arising out of the use of the Content. We sincerely acknowledge the managers of the cotton-ginning mills for allowing us to conduct our study there. We also gratefully acknowledge the medical assistance and guidance provided by Dr. Premchand Mahajan (MD Pathology) and Dr. Chandrakant Barela during our study. We are also grateful to North Maharashtra University, Jalgaon, for technical support. Dust generated during the handling and processing of cotton causes ill health of ginning workers. The purpose of this study was to determine the prevalence of respiratory symptoms among cotton-ginning workers. This study involved 188 workers of 10 cotton-ginning factories. Forced vital capacity (FVC), peak expiratory flow rate (PEFR), and forced expiratory volume in 1 s (FEV 1) declined significantly with increasing duration of exposure (p < .001) of the cotton-ginning workers. Results of a standard respirator medical evaluation questionnaire indicated that, depending on duration of exposure, 51%–71% of cotton-ginning workers suffered from chest tightness, 55%–62% experienced chest pain, while 33%–42% of the workers reported frequent cough. Blood tests of the workers showed higher values of erythrocyte sedimentation rate, eosinophils, and white blood cells when exposure was longer. Byssinosis symptoms were observed among the workers. We recommend regular periodical medical checkups , compulsory use of personal protective equipment, and proper ventilation at the workplace. dust concentration cotton dust pulmonary function test blood test byssinosis symptoms
Full name of Institution: Department of Foreign Languages fluent bilingual English/Spanish speakers; and advanced English L2 learners of Spanish. Using reaction time grammaticality judgment tests

Cook (1992) suggests that when testing the acquisition of subtle UG properties, the linguistic competence of the advanced L2 learner should be measured against the competence of an L1/L2 fluent bilingual and not that of an L2 monolingual because of differing cognitive processes between bilinguals and monolinguals. The goal of this empirical study is to compare the use of that-trace effects in Spanish by three groups: monolingual Spanish speakers; fluent bilingual English/Spanish speakers; and advanced English L2 learners of Spanish. Using reaction time grammaticality judgment tests and a follow-up interview on the subjects’ judgments, the results show differences between the bilingual and monolingual groups, suggesting that the L2 learners are performing like bilinguals. The implications of these results might suggest an additional approach to testing advanced L2 learners on acquisition of UG properties and help clarify the question of UG access during SLA.
Differential γ-Herpesvirus Distribution in Distinct Anatomical Locations and Cell Subsets During Persistent Infection in Mice1

Murine γ-herpesvirus 68 (MHV-68) provides an important experimental model for analyzing γ-herpesvirus latent infection. After intranasal infection with MHV-68, we analyzed the distribution of the virus in different anatomical locations and purified populations of cells. Our data show that long-term latency is maintained in a variety of anatomical locations and cell populations with different frequencies. Importantly, we demonstrate that although latency in the lung is established in a variety of cell subsets, long-term latency in the lung is only maintained in B cells. In contrast, splenic latency is maintained in macrophages and dendritic cells, as well as in B cells. In blood, isotype-switched B cells constitute the major viral reservoir. These results show that the cell subsets in which latency is established vary within different anatomical sites. Finally, we demonstrate that long-term latency is accompanied by a low level of infectious virus in lung and spleen. These data have important implications for understanding the establishment and maintenance of latency by γ2-herpesviruses.
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities

Purpose The aim of the present study was to develop nanoprobes with theranostic features, including – at the same time – photoacoustic, near-infrared (NIR) optical imaging, and photothermal properties, in a versatile and stable core–shell silica-polyethylene glycol (PEG) nanoparticle architecture. Materials and methods We synthesized core–shell silica-PEG nanoparticles by a one-pot direct micelles approach. Fluorescence emission and photoacoustic and photothermal properties were obtained at the same time by appropriate doping with triethoxysilane-derivatized cyanine 5.5 (Cy5.5) and cyanine 7 (Cy7) dyes. The performances of these nanoprobes were measured in vitro, using nanoparticle suspensions in phosphate-buffered saline and blood, dedicated phantoms, and after incubation with MDA-MB-231 cells. Results We obtained core–shell silica-PEG nanoparticles endowed with very high colloidal stability in water and in biological environment, with absorption and fluorescence emission in the NIR field. The presence of Cy5.5 and Cy7 dyes made it possible to reach a more reproducible and higher doping regime, producing fluorescence emission at a single excitation wavelength in two different channels, owing to the energy transfer processes within the nanoparticle. The nanoarchitecture and the presence of both Cy5.5 and Cy7 dyes provided a favorable agreement between fluorescence emission and quenching, to achieve optical imaging and photoacoustic and photothermal properties. Conclusion We obtained rationally designed nanoparticles with outstanding stability in biological environment. At appropriate doping regimes, the presence of Cy5.5 and Cy7 dyes allowed us to tune fluorescence emission in the NIR for optical imaging and to exploit quenching processes for photoacoustic and photothermal capabilities. These nanostructures are promising in vivo theranostic tools for the near future.
Explaining Socially Responsible Consumer Behavior: A Meta-Analytic Review of Theory of Planned Behavior

ABSTRACT This study reviews previous studies on socially responsible consumers and identifies major antecedents of behavioral intentions to contribute to the theoretical understanding of their purchase behaviors. Meta-analytic procedures were used to (1) quantify the relationship between theory of planned behavior (TPB) constructs, (2) examine the contribution of additional predictors to explain behavioral intention, and (3) identify moderators that influence the strength of the relationships between TPB constructs. The results reveal key factors underlying the consumer decision-making process and provide useful information for marketers in developing strategies that can increase acceptance and purchase of products/services that address consumers' ethical concerns.
The mechanisms for pattern completion and pattern separation in the hippocampus

The mechanisms for pattern completion and pattern separation are described in the context of a theory of hippocampal function in which the hippocampal CA3 system operates as a single attractor or autoassociation network to enable rapid, one-trial, associations between any spatial location (place in rodents, or spatial view in primates) and an object or reward, and to provide for completion of the whole memory during recall from any part. The factors important in the pattern completion in CA3 together with a large number of independent memories stored in CA3 include a sparse distributed representation which is enhanced by the graded firing rates of CA3 neurons, representations that are independent due to the randomizing effect of the mossy fibers, heterosynaptic long-term depression as well as long-term potentiation in the recurrent collateral synapses, and diluted connectivity to minimize the number of multiple synapses between any pair of CA3 neurons which otherwise distort the basins of attraction. Recall of information from CA3 is implemented by the entorhinal cortex perforant path synapses to CA3 cells, which in acting as a pattern associator allow some pattern generalization. Pattern separation is performed in the dentate granule cells using competitive learning to convert grid-like entorhinal cortex firing to place-like fields. Pattern separation in CA3, which is important for completion of any one of the stored patterns from a fragment, is provided for by the randomizing effect of the mossy fiber synapses to which neurogenesis may contribute, by the large number of dentate granule cells each with a sparse representation, and by the sparse independent representations in CA3. Recall to the neocortex is achieved by a reverse hierarchical series of pattern association networks implemented by the hippocampo-cortical backprojections, each one of which performs some pattern generalization, to retrieve a complete pattern of cortical firing in higher-order cortical areas.
Solar forced Dansgaard‐Oeschger events and their phase relation with solar proxies

North Atlantic climate during glacial times was characterized by large‐amplitude switchings, the Dansgaard‐Oeschger (DO) events, with an apparent tendency to recur preferably in multiples of about 1470 years. Recent work interpreted these intervals as resulting from a subharmonic response of a highly nonlinear system to quasi‐periodic solar forcing plus noise. This hypothesis was challenged as inconsistent with the observed variability in the phase relation between proxies of solar activity and Greenland climate. Here we reject the claim of inconsistency by showing that this phase variability is a robust, generic feature of the nonlinear dynamics of DO events, as described by a model. This variability is expected from the fact that the events are threshold crossing events, resulting from a cooperative process between the periodic forcing and the noise. This process produces a fluctuating phase relation with the periodic forcing, consistent with proxies of solar activity and Greenland climate.
Genome I nstability of Chironomus riparius Mg . ( Diptera , Chironomidae ) from P olluted W ater B asins in Bulgaria

Larvae of Chironomus riparius Mg. (Chironomidae, Diptera) collected from two polluted water basins in Bulgaria, the Maritsa and Chaya Rivers (adjacent to Plovdiv and Asenovgrad respectively), a small pool (near Plovdiv) plus controls reared in the laboratory were studied. High concentrations of the heavy metals Pb, Cu and Cd were recorded in the sediments of the polluted stations. Marked somatic structural chromosome aberrations were found in C. riparius salivary polytene chromosomes from the field stations and their frequency was significantly higher (p<0.01) compared to the control. The observed somatic chromosome changes are discussed as a response of the chironomid genome to aquatic pollution. A new cytogenetic index based on the number of aberrations found in larvae from polluted regions in comparison with the control was applied to the data to more easily evaluate the degree of heavy metal pollution in aquatic ecosystems. Our study of a polluted site near the River Chaya showed that the somatic index was very high at 3.35 for 2010 and 11.66 for 2013 compared to 0.5 in the control. The cytogenetic index was effective in showing that all studied sites were highly polluted in comparison with the control. To determine the mechanism involved in the concentration of aberration breakpoints within specific regions of the chironomid polytene chromosome the FISH method was applied. The localization of a transposable element TFB1 along the polytene chromosomes of C. riparius was analyzed and the sites of localization were compared with breakpoints of chromosome aberrations. A significant correlation (p<0.05) was found which shows that most of the aberrations do not appear randomly but are concentrated in sites rich in transposable elements.
Expression Divergence of Chemosensory Genes between Drosophila sechellia and Its Sibling Species and Its Implications for Host Shift

Drosophila sechellia relies exclusively on the fruits of Morinda citrifolia, which are toxic to most insects, including its sibling species Drosophila melanogaster and Drosophila simulans. Although several odorant binding protein (Obp) genes and olfactory receptor (Or) genes have been suggested to be associated with the D. sechellia host shift, a broad view of how chemosensory genes have contributed to this shift is still lacking. We therefore studied the transcriptomes of antennae, the main organ responsible for detecting food resource and oviposition, of D. sechellia and its two sibling species. We wanted to know whether gene expression, particularly chemosensory genes, has diverged between D. sechellia and its two sibling species. Using a very stringent definition of differential gene expression, we found a higher percentage of chemosensory genes differentially expressed in the D. sechellia lineage (7.8%) than in the D. simulans lineage (5.4%); for upregulated chemosensory genes, the percentages were 8.8% in D. sechellia and 5.2% in D. simulans. Interestingly, Obp50a exhibited the highest upregulation, an approximately 100-fold increase, and Or85c—previously reported to be a larva-specific gene—showed approximately 20-fold upregulation in D. sechellia. Furthermore, Ir84a (ionotropic receptor 84a), which has been proposed to be associated with male courtship behavior, was significantly upregulated in D. sechellia. We also found expression divergence in most of the chemosensory gene families between D. sechellia and the two sibling species. Our observations suggest that the host shift of D. sechellia was associated with the enrichment of differentially expressed, particularly upregulated, chemosensory genes.
Replication-Competent Influenza A and B Viruses Expressing a Fluorescent Dynamic Timer Protein for In Vitro and In Vivo Studies

Influenza A and B viruses (IAV and IBV, respectively) cause annual seasonal human respiratory disease epidemics. In addition, IAVs have been implicated in occasional pandemics with inordinate health and economic consequences. Studying influenza viruses in vitro or in vivo requires the use of laborious secondary methodologies to identify infected cells. To circumvent this requirement, replication-competent infectious influenza viruses expressing an easily traceable fluorescent reporter protein can be used. Timer is a fluorescent protein that undergoes a time-dependent color emission conversion from green to red. The rate of spectral change is independent of Timer protein concentration and can be used to chronologically measure the duration of its expression. Here, we describe the generation of replication-competent IAV and IBV where the viral non-structural protein 1 (NS1) was fused to the fluorescent dynamic Timer protein. Timer-expressing IAV and IBV displayed similar plaque phenotypes and growth kinetics to wild-type viruses in tissue culture. Within infected cells, Timer’s spectral shift can be used to measure the rate and cell-to-cell spread of infection using fluorescent microscopy, plate readers, or flow cytometry. The progression of Timer-expressing IAV infection was also evaluated in a mouse model, demonstrating the feasibility to characterize IAV cell-to-cell infections in vivo. By providing the ability to chronologically track viral spread, Timer-expressing influenza viruses are an excellent option to evaluate the in vitro and in vivo dynamics of viral infection.