Miracle-dz/UniFAR-FTUs huggingface dataset:
Bone Replacement of Fast-Absorbing Biocomposite Anchors in Arthroscopic Shoulder Labral Repairs

Background: Newer generation biocomposite anchors are hypothesized to resorb more reliably and faster, while allowing for bone ingrowth and replacement. Purpose: The purposes of this study were to (1) assess anchor resorption and bone ingrowth over time, (2) identify tunnel widening or potential reactions to the implants, (3) compare imaging findings for different sites of labral repair, and (4) determine patient subjective outcomes with the use of biocomposite anchors in glenoid labral repair. Study Design: Case series; Level of evidence, 4. Methods: We enrolled 22 patients to participate in a 24-month outcomes study that included subjective and objective outcome assessments after glenoid labrum repair surgery. Magnetic resonance imaging (MRI) was performed at 6 and 12 months to identify any potential reactions to implants. Computed tomography (CT) scans were performed at 12 and 24 months to determine anchor resorption and bone ingrowth. Sixteen patients and 47 anchors were available for follow-up at 24 months. An independent, fellowship-trained musculoskeletal radiologist read the scans. Subjective outcome scores measured at 24 months postoperatively included Simple Shoulder Test, Tegner activity scale, American Shoulder and Elbow Surgeons (ASES), and University of California, Los Angeles (UCLA) shoulder scores. Results: No adverse events were reported with the use of biocomposite anchors at the end of the study period. At 12 and 24 months, respectively, CT scans demonstrated that an estimated 68% and 98% of combined anchor material had been absorbed, 56% and 78% of the anchor material had been replaced by soft tissue of variable density, and 9% and 20% of total anchor volume was replaced by bone. No obvious mechanical failure of the labral repairs was detected on nonarthrogram MRI. Three of the 47 anchors showed bone cyst formation. Tunnel widening (expansion beyond tunnel diameter of 3 mm; 2.9-mm drill hole utilized) was seen in 55% of the anchors but decreased between 12 and 24 months, consistent with bone replacement. Tunnel widening was seen more in anteroinferior and posterior glenoid anchor locations (84% and 57%, respectively) than in superior labral anchors (13%). Subjective outcome scores at 24 months for ASES and UCLA shoulder scores averaged 88 and 30, respectively. All but one patient were satisfied with their outcome at 24 months. Conclusion: Our imaging evaluation indicates resorption of newer generation biocomposite anchors with progressive bone replacement at 12 and 24 months while maintaining acceptable subjective outcomes.
Results on the fundamental gain of memory-assisted universal source coding

Many applications require data processing to be performed on individual pieces of data which are of finite sizes, e.g., files in cloud storage units and packets in data networks. However, traditional universal compression solutions would not perform well over the finite-length sequences. Recently, we proposed a framework called memory-assisted universal compression that holds a significant promise for reducing the amount of redundant data from the finite-length sequences. The proposed compression scheme is based on the observation that it is possible to learn source statistics (by memorizing previous sequences from the source) at some intermediate entities and then leverage the memorized context to reduce redundancy of the universal compression of finite-length sequences. We first present the fundamental gain of the proposed memory-assisted universal source coding over conventional universal compression (without memorization) for a single parametric source. Then, we extend and investigate the benefits of the memory-assisted universal source coding when the data sequences are generated by a compound source which is a mixture of parametric sources. We further develop a clustering technique within the memory-assisted compression framework to better utilize the memory by classifying the observed data sequences from a mixture of parametric sources. Finally, we demonstrate through computer simulations that the proposed joint memorization and clustering technique can achieve up to 6-fold improvement over the traditional universal compression technique when a mixture of non-binary Markov sources is considered.
The Influence of Individual Differences on Emotional Processing and Emotional Memory

v Introduction 1 Memory Enhancement of Emotional Material 2 Mechanisms for Emotional Memory Enhancement 3 Increased Attention and Emotional Memory 4 Amygdala Involvement and Emotional Memory 7 Other Connections and Emotional Memory 9 Affective Processing and ERP 11 Early/Middle ERP Components 11 The LPP Component 14 Individual Differences in Emotional Picture Processing and Memory 17 Early/Middle Components 20 The LPP Component 21 Purpose of the Current Study 22 Hypotheses and Predictions 24 Methods 25 Participants 25 Materials 26 Procedure 30 Piloting 30 Study Procedure 31 Scoring of Data 33 Results 37 Data Diagnostics 37 Method Diagnostics 39 Hypothesis 1: BIS/BAS and Recall/Recognition 42 Overall Free Recall Rates 40 Overall Recognition Reaction Time Rates 41 Overall Recognition Sensitivity Analysis 41
Secretory Granule Proteases in Rat Mast Cells. Cloning of 10 Different Serine Proteases and a Carboxypeptidase A from Various Rat Mast Cell Populations

Two of the major rat mast cell proteases, rat mast cell protease 1 (RMCP-1) and RMCP-2, have for many years served as important phenotypic markers for studies of various aspects of mast cell (MC) biology. However, except for these proteases only fragmentary information has been available on the structure and complexity of proteases expressed by different subpopulations of rat MCs. To address these questions, cDNA libraries were constructed from freshly isolated rat peritoneal MCs and from the rat mucosal MC line RBL-1. cDNA clones for 10 different serine proteases (RMCP-1-10), and the MC carboxypeptidase A were isolated and characterized. Six of these proteases have not been isolated previously. Based on their protease content, three separate subpopulations of MCs were identified. Connective tissue MCs (CTMCs) from the ear and peritoneum express the chymases RMCP-1 and -5, the tryptases RMCP-6, and -7 and the carboxypeptidase A. However, based on a large difference in the level of expression of RMCP-7, CTMCs of these two organs may be regarded as two separate subpopulations. RMCP-2 and the three closely related proteases of the RMCP-8 subfamily were identified as the major mucosal MC proteases in rat. In contrast to what has been reported for human MCs, no expression of cathepsin G or cathepsin G–like proteases was detected in any of the rat MC populations. To determine mRNA frequencies for the various proteases expressed by normal tissue MCs, an unamplified peritoneal MC cDNA library was screened with a panel of monospecific cDNA probes. These results showed that peritoneal MCs are highly specialized effector cells with mRNA frequencies for the major proteases in the range of several percent of the total mRNA pool.
Customized mandibular reconstruction plates improve mechanical performance in a mandibular reconstruction model

Abstract The purpose of this paper was to analyze the biomechanical performance of customized mandibular reconstruction plates with optimized strength. The best locations for increasing bar widths were determined with a sensitivity analysis. Standard and customized plates were mounted on mandible models and mechanically tested. Maximum stress in the plate could be reduced from 573 to 393 MPa (−31%) by increasing bar widths. The median fatigue limit was significantly greater (p < 0.001) for customized plates (650 ± 27 N) than for standard plates (475 ± 27 N). Increasing bar widths at case-specific locations was an effective strategy for increasing plate fatigue performance.
Thermophysical and anion diffusion properties of (Ux,Th1−x)O2

Using molecular dynamics, the thermophysical properties of the (Ux,Th1−x)O2 system have been investigated between 300 and 3600 K. The thermal dependence of lattice parameter, linear thermal expansion coefficient, enthalpy and specific heat at constant pressure is explained in terms of defect formation and diffusivity on the oxygen sublattice. Vegard's law is approximately observed for solid solution thermal expansion below 2000 K. Different deviations from Vegard's law above this temperature occur owing to the different temperatures at which the solid solutions undergo the superionic transition (2500–3300 K). Similarly, a spike in the specific heat, associated with the superionic transition, occurs at lower temperatures in solid solutions that have a high U content. Correspondingly, oxygen diffusivity is higher in pure UO2 than in pure ThO2. Furthermore, at temperatures below the superionic transition, oxygen mobility is notably higher in solid solutions than in the end members. Enhanced diffusivity is promoted by lower oxygen-defect enthalpies in (Ux,Th1−x)O2 solid solutions. Unlike in UO2 and ThO2, there is considerable variety of oxygen vacancy and oxygen interstitial sites in solid solutions generating a wide range of property values. Trends in the defect enthalpies are discussed in terms of composition and the lattice parameter of (Ux,Th1−x)O2.
Molecular Detection of Disseminated Tumor Cells in the Peripheral Blood of Patients with Gastric Cancer: Evaluation of Their Prognostic Significance

Early detection of disseminated tumor cells in the peripheral blood of patients with early stage gastric cancer could help to improve the outcome after tumor resection. The aim of this study is to evaluate the prognostic significance of tumor-related mRNA for the detection of circulating tumor cells in gastric cancer patients by a reverse-transcriptase polymerase chain reaction (RT-PCR) method. We simultaneously analyzed human telomerase reverse transcriptase (hTERT), cytokeratin-19 (CK-19), cytokeratin-20 (CK-20) and carcinoembryonic antigen (CEA) mRNA (messenger RNA) expression in the peripheral blood of 42 gastric cancer patients and 30 healthy individuals. Additionally, analyses were carried out for the correlation of these four molecular markers with patients’ clinicopathologic features, as well as the occurrence of postoperative recurrence/metastasis. Among 42 gastric cancer patients, the prevalence of mRNA for hTERT, CK-19, CK-20, and CEA was 61.9% (26/42), 69% (29/42), 61.9% (26/42), and 78.6% (33/42), respectively. All 30 healthy individuals were negative for hTERT and CEA mRNA, while two were positive for either CK-19 mRNA or CK-20 mRNA. Positive CEA mRNA was significantly correlated with tumor size (p = 0.008), vessel invasion (p = 0.001), depth of tumor invasion (p = 0.007), lymph node metastasis (p < 0.001), and TNM stage (p < 0.001). In addition, the multivariate logistic regression demonstrated that CEA mRNA expression was an independent and significant predictor for postoperative recurrence/metastasis (p = 0.032). Our findings suggest that CEA mRNA may be a more reliable marker than hTERT, CK-19 and CK-20 for the detection of circulating cancer cells in gastric cancer patients' peripheral blood. Patients with positive CEA mRNA expression in peripheral blood have a significantly higher risk of postoperative recurrence/metastasis.
Gender Studies In Cuba

Cuban scholarly works on gender are little known outside Cuba. This article summarizes characteristics of the gender approaches used by social scientists in Cuba, stressing their methodological views, the methods they use, the non-Cuban authors who have influenced their works, and the social context in which gender studies started in Cuban academia. It includes an appendix listing works by the 24 scholars interviewed by the author.
Direction of the J-Tip of the Guidewire, in Seldinger Technique, Is a Significant Factor in Misplacement of Subclavian Vein Catheter: A Randomized, Controlled Study

Misplacement of central venous catheters, predisposing to poor functioning including inability to aspirate blood, is common with the subclavian approach. In this prospective study we sought to determine whether the direction of the guidewire J-tip influenced the catheter tip placement during right subclavian catheterization. In this randomized, double-blind clinical study, we observed the placement of catheters via the right subclavian vein while keeping the J-tip directed either caudad in Group 1 (n = 147) or cephalad in Group 2 (n = 148) patients. The majority of catheters (97% and 57%) in Groups 1 and 2 respectively entered the superior vena cava/right atrium (P < 0.05). The incidence of catheter misplacement into the ipsilateral internal jugular vein was 2% and 40% in Groups 1 and 2, respectively (P = < 0.01). Subsequent experimental study confirmed that the direction of the J-tip was retained inside a model of vascular tubes and its tip led the guidewire into the tubing on the same side even at the acute angulation formed between tubings representing the subclavian, internal jugular, and superior vena cava junction complex. The authors conclude that the simple measure of keeping the guidewire J-tip directed caudad increased correct placement of central venous catheters towards the right atrium during right subclavian catheterization.
INFLUENCES OF ENVIRONMENTAL EDUCATION PROGRAMS ON THE PARTICIPANT’S AFFINITY FOR NATURE

Influences of Environmental Education Programs on the Participant’s Affinity For Nature Justin Alan Schmillen This study was conducted to determine the change, and the factors influencing the change, in the participant’s affinity for nature resulting from an environmental education experience. In addition, this study also examined the change and factors of change in aspects of the participant’s affinity for nature that directly relate to marine and coastal resources and environments. An adapted version of the Affinity for Nature scale, an outcome measuring instrument used by the American Camp Association was used to collect data from participants (n=529) at Rancho El Chorro Outdoor School and Camp Ocean Pines, whose experience included an overnight component and a marine science component in the curriculum. Comparisons of overall mean scores were used to determine if affinity for nature changed due to participation in the environment education program. Analysis of variance was used to determine which participant characteristic and experiential variables had a significant influence on affinity for nature index scores. Findings indicated that participation in environmental education experience had a positive change on affinity for nature scores. Residence, ethnicity/language, and gender were also found to significantly influence sense of community various affinity for nature index scores.
Omega-3 lipid infusion in a heart allotransplant model. Shift in fatty acid and lipid mediator profiles and prolongation of transplant survival.

BACKGROUND omega-3 Fatty acids may have a major impact on immune responses involved in heart transplant rejection. We compared the effects of posttransplant intravenous supplementation with omega-3-rich versus omega-6-rich lipid emulsions on graft survival, plasma fatty acid profiles, and levels of arachidonic acid versus eicosapentaenoic acid-derived lipid mediators. METHODS AND RESULTS Inbred PVG and Wistar-Kyoto rats were used as donors and recipients, respectively, in a model of heterotopic heart transplantation. Animals received 9 g/kg body wt per day of either fish oil-derived (n = 8) or soybean oil-derived fat (n = 7) in the form of a continuously infused lipid emulsion; controls were sham-infused with saline (n = 8). Graft rejection was assessed by loss of activity of the transplant. The fish oil-derived preparation but not that originating from soybean oil caused an increase in total and free plasma fatty acids. Substantial quantities of eicosapentaenoic acid and docosahexaenoic acid appeared in the free fatty acid fraction, surpassing those of arachidonic acid. Ex vivo stimulation of neutrophils with the Ca2+ ionophore A23187 demonstrated an increase in 5-series leukotriene (LT) generation in animals undergoing omega-3 lipid infusion (LTB5, omega-oxidation products of LTB5, LTA5 secretion), with 5-series/4-series LT ratios ranging between 0.08 and 0.36. Ratios of TX B3/B2 liberated from ex vivo stimulated platelets even approached 1:1 in omega-3 supplemented rats. Graft survival was 7.6 +/- 0.3 (mean +/- SEM) days in saline-infused, 10.4 +/- 0.7 in omega-6 lipid-infused, and 12.9 +/- 0.4 in omega-3 lipid-infused animals. CONCLUSIONS Posttransplant intravenous alimentation with fish oil-derived lipid emulsions prolongs heart transplant survival in excess to omega-6 lipids. Profound changes in fatty acid profiles and lipid mediator generation may underlie this finding.
THE RHYTHM NETWORK: AN ACTIVATION AND FUNCTIONAL CONNECTIVITY ANALYSIS OF BEAT PERCEPTION AND PRODUCTION

The perception of beat, while seeming easy and intuitive, is a rather complex cognitive and sensorimotor achievement that at times can manifest as a visceral sensation. Deficits in beat perception also appear to positively correlate with increased impairment in movement disorders such Parkinson's disease. Neuroimaging has shown findings like these are likely due to rhythm perception and production relying on a complex interaction of auditory and motor regions, in association with a supportive network that includes prefrontal, parietal, and deep striatal areas of the brain. This study therefore aimed (I) to use traditional task-based activation techniques (fMRI) to define the critical regions of the rhythm network under both a beat rating (BR) and beat production/maintenance (BPM) cognitive task; and (II) employ task-based functional connectivity (fcMRI) methods, to map the most important connections within this network, highlighting how they may change dependent on task behavior and stimuli. Activation results for 14 normal right handed participants (4F : 10M, 24 yrs ? 4.54) confirmed much of the current literature and indicated that both beat perception and production recruit neural resources from predominantly overlapping regions of a single network. Functional connectivity analyses described a network whose connectivity is relatively stable regardless of stimuli or task. Differences between perception and production of rhythm appear to stem from specific, subtle changes in the synchronicity between particular regions. To our knowledge, the correlation matrices and connectivity maps derived from our fMRI-fcMRI data are the first comprehensive representations of the rhythm network as a whole.
A study on the investigation of cadmium chloride genotoxicity in rat bone marrow using micronucleus test and chromosome aberration analysis

In this study, we investigated the genotoxic and cytotoxic potential of cadmium chloride (CdCl2)in Wistar rat tibia bone marrow cells, using the structural chromosomal aberration (SCA) and micronucleus (MN) test systems. CdCl2 was administered to adult female rats as repeated i.p. doses of 0.5 mg/kg b.w. for 18 week (four months) at 48 h intervals. Mitomycin C (MMC) was used as a positive control (2 mg/kg b.w.). This study shows that cadmium chloride treatment significantly induced the frequency of micronucleus in polychromatic erythrocytes in tibia bone marrow. This increase in micronucleus frequency shows that cadmium has a genotoxic effect on bone marrow at this level. Also, in order to determine cytotoxicity in bone marrow, the ratio of polychromatic erythrocytes to normochromatic erythrocytes was calculated in bone marrow. The results of this study indicate that CdCl2 decreased this ratio. The decrease of this ratio in bone marrow shows CdCl2 may lead to cytotoxicity. We have reported that 0.5 mg/kg-level chronic exposure to cadmium (Cd) has an injurious effect on bone marrow. Our findings indicate that CdCl2 has a cytotoxic and genotoxic effect on rat bone marrow at chronic exposure.
Effect of 15% carbamide peroxide bleaching gel on color stability of giomer and microfilled composite resin: An in vitro comparison

Objectives: The effect of 15% carbamide peroxide bleaching gel on color stability and surface topography of a giomer and a microfilled composite resin was evaluated in the present in vitro study. Study design: Forty discs measuring 10 mm in diameter and 1 mm in thickness were prepared from a giomer and a microfilled composite resin. Each material yielded 20 discs with completely smooth surfaces. Then a spectrophotometer was used to measure L* (lightness), a* (redness, greenness) and b* (blueness, yellowness) color coordinates of all the discs. Subsequently, the specimens were subjected to 15% carbamide peroxide bleaching gel. After measuring the color coordinates once again, color changes (ΔE*) were calculated by the CIELAB system. Six specimens from each material (three specimens before bleaching agent application and three specimens thereafter) were viewed under an atomic force microscope (AFM) for surface topography evaluation. Data were analyzed by Mann-Whitney U and Kruskal-Wallis tests at α=0.05. Results: There were no statistically significant differences in color changes (ΔE*) between the two materials (P>0.05). In addition, no significant differences were detected in surface roughness between composite resin and giomer discs before and after bleaching (P>0.05 for both). However, in both materials the differences in surface roughness were significant before and after bleaching procedures (P<0.001). Conclusions: Based on the results of the present study it was concluded that 15% carbamide peroxide does not induce clinically detectable color changes in composite resin and giomer despite an increase in surface roughness. Key words:Bleaching, color stability, giomer, microfilled composite.
Identity as a ‘patchwork’: aspects of identity among low-income Brazilian travestis

This paper is based on findings from a qualitative study that took place within the context of a four-year healthcare programme directed towards low-income travestis in the central area of São Paulo, Brazil. Throughout the study the formation of social identity among travestis was investigated through a focus on four axes: gender, body, work and violence. This paper subjects the identity of the travestis to a critical analysis and proposes a view of their sense of self as a ‘patchwork’ assembled through the assimilation of various fragments of identity common in Brazilian society. The primary identities assimilated by the travestis under study were, in the area of femininity, the submissive woman, the puta [‘whore’] and the super-seductive woman and, in the area of masculinity, the viado [‘queer’], the malandro [‘rascal’] and the bandido [‘bandit’]. The resulting travesti identity exhibited not only gender ambiguity, but also contradictions among the feminine identities described, as well as among the masculine ones.
Experimental Confirmation of a PDE-Based Approach to Design of Feedback Controls

Issues regarding the experimental implementation of PDE-based controllers are discussed in this work. While the motivating application involves the reduction of vibration levels for a circular plate through excitation of surface-mounted piezoceramic patches, the general techniques described here will extend to a variety of applications. The initial step is the development of a PDE model which accurately captures the physics of the underlying process. This model is then discretized to yield a vector-valued initial value problem. Optimal control theory is used to determine continuous-time voltages to the patches, and the approximations needed to facilitate discrete-time implementation are addressed. Finally, experimental results demonstrating the control of both transient and steady-state vibrations through these techniques are presented.