Miracle-dz/UniFAR-FTUs huggingface dataset:
Using Expectancy Value Theory as a Framework to Reduce Student Resistance to Active Learning: A Proof of Concept

There has been a national movement to transition college science courses from passive lectures to active learning environments. Active learning has been shown to be a more effective way for students to learn, yet there is concern that some students are resistant to active learning approaches. Although there is much discussion about student resistance to active learning, few studies have explored this topic. Furthermore, a limited number of studies have applied theoretical frameworks to student engagement in active learning. We propose using a theoretical lens of expectancy value theory to understand student resistance to active learning. In this study, we examined student perceptions of active learning after participating in 40 hours of active learning. We used the principal components of expectancy value theory to probe student experience in active learning: student perceived self-efficacy in active learning, value of active learning, and potential cost of participating in active learning. We found that students showed positive changes in the components of expectancy value theory and reported high levels of engagement in active learning, which provide proof of concept that expectancy value theory can be used to boost student perceptions of active learning and their engagement in active learning classrooms. From these findings, we have built a theoretical framework of expectancy value theory applied to active learning.
Soy goes to school: acceptance of healthful, vegetarian options in Maryland middle school lunches.

BACKGROUND Soyfoods provide healthful options for school breakfasts and lunches that are lower in saturated fat, cholesterol, fat, and calories and can help meet demands for vegetarian choices. Researchers tested acceptance of soy-based options substituted for popular lunch items with a diverse student population. METHODS Researchers conducted a plate waste study in 5 middle schools in Montgomery County, Maryland, to test the comparability of soy-based alternatives to 4 popular meat-based menu items. Initially, students ranked taste, appearance, and texture of 15 soyfoods to narrow to "hybrid" beef patties, soy-based nuggets, soy-based chicken-less slices, and soy macaroni and cheese. After the meal, trained observers randomly tagged and collected trays with and without test items and weighed leftover entrées. Researchers used a proportional odds model to compare amounts and proportions of food consumed, and a mixed model to account for differences between schools. RESULTS Students consumed the same amount of soy-based and traditional patties, nuggets, and pasta, and less soy than regular chicken in the salad (odds ratio 0.122, p value < .0001). Students consumed higher proportions (p value < .05) of traditional chicken nuggets, beef patties, chicken slices, and pasta compared to soy-based alternative products. On average, soy-based entrées had fewer calories; less total fat, saturated fat, and cholesterol; and more iron, fiber, and sodium compared to traditional menu items. CONCLUSIONS This study indicates that middle school students readily consume almost equal numbers of soy-based products compared to popular school lunch items. Soyfoods provide nutritional advantages.
SOIL STRUCTURE INTERACTION IN THE ANALYSIS AND SEISMIC DESIGN OF REINFORCED CONCRETE FRAME BUILDINGS

The influence of soil-structure interaction in the analysis and design of a 6-storey and basement reinforced concrete frame building is investigated. Models simulating two different conditions: namely soil-structure interaction, and fixed-base behavior are considered. The influence of the soil structure interaction in the dynamic behavior of the structure is reflected in an increase in the vibration period as well as increase in the system damping in comparison with the fixed-base model, which does not consider the supporting soil. The influence of the soil-structure interaction in the seismic design of the structure is reflected in a decrease of the horizontal spectral acceleration values. The inclusion of the soil in the structural analysis provides results, stress and displacement values, which are closer to the actual behavior of the structure than those provided by the analysis of a fixed-base structure.
Scheduling in practice

In queueing theory, it has been known for a long time that the scheduling policy used in a system greatly impacts user-perceived performance. For example, it has been proven in the 1960's that size-based scheduling policies that give priority to short jobs are optimal with respect to mean response time. Yet, virtually no systems today implement these policies. One reason is that real systems are significantly more complex than a theoretical M/M/1 or M/G/1 queue and it is not obvious how to implement some of these policies in practice. Another reason is that there is a fear that the big jobs will "starve", or be treated unfairly as compared to Processor-Sharing (PS). In this article we show, using two important real world applications, that size-based scheduling can be used in practice to greatly improve mean response times in real systems, without causing unfairness or starvation. The two applications we consider are connection scheduling in web servers and packet scheduling in network routers.
Diffusion of Mobile Entertainment in Malaysia: Drivers and Barriers

— This research aims to examine the key success factors for the diffusion of mobile entertainment services in Malaysia. The drivers and barriers observed in this research include perceived benefit; concerns pertaining to pricing, product and technological standardization, privacy and security; as well as influences from peers and community. An analysis of a Malaysian survey of 384 respondents between 18 to 25 years shows that subscribers placed greater importance on perceived benefit of mobile entertainment services compared to other factors. Results of the survey also show that there are strong positive correlations between all the factors, with pricing issue — perceived benefit showing the strongest relationship. This paper aims to provide an extensive study on the drivers and barriers that could be used to derive architecture for entertainment service provision to serve as a guide for telcos to outline suitable approaches in order to encourage mass market adoption of mobile entertainment services in Malaysia.
Joint Beamforming and Power Control for Device-to-Device Communications Underlaying Cellular Networks

In this paper, we address the issue of joint beamforming (BF) and power control for a device-to-device (D2D) communication underlaying cellular network, where the wireless channels of the D2D link and the base station to user equipment link experience Rician and correlated Rayleigh fading, respectively. Based on the property of the integral network, we first formulate a constrained optimization problem to minimize the total transmit power of the devices in the network, while meeting the quality-of-service requirement of both the D2D and cellular users and suppressing the mutual interference to a certain level. Then, by adopting the available statistical channel state information and proposing an approximation method to relax the constraints, a support-vector-machine-based algorithm is presented to solve the optimization problem for the transmit powers and BF weight vectors of each user. Furthermore, we derive the analytical expressions for the cumulative density function and the generalized moments of the output signal-to-interference-plus-noise ratios, thereby developing some novel theoretical formulas for the ergodic capacity and the average symbol error rate of each user in the network. Finally, computer simulation results are provided to demonstrate the validity and efficiency of the proposed scheme and its performance analysis.
Farnesoid X Receptor Ligand Prevents Cisplatin-Induced Kidney Injury by Enhancing Small Heterodimer Partner

The farnesoid X receptor (FXR) is mainly expressed in liver, intestine and kidney. We investigated whether 6-ethyl chenodeoxycholic acid (6ECDCA), a semisynthetic derivative of chenodeoxycholic aicd (CDCA, an FXR ligand), protects against kidney injury and modulates small heterodimer partner (SHP) in cisplatin-induced kidney injury. Cisplatin inhibited SHP protein expression in the kidney of cisplatin-treated mice and human proximal tubular (HK2) cells; this effect was counteracted by FXR ligand. Hematoxylin and eosin staining revealed the presence of tubular casts, obstructions and dilatations in cisplatin-induced kidney injury, which was attenuated by FXR ligand. FXR ligand also attenuated protein expression of transforming growth factor-β1 (TGF-β1), Smad signaling, and the epithelial-to-mesenchymal transition process, inflammatory markers and cytokines, and apoptotic markers in cisplatin-treated mice. Cisplatin induced NF-κB activation in HK2 cell; this effect was attenuated by pretreatment with FXR ligand. In SHP knockdown by small interfering RNA, cisplatin-induced activation of TGF-β1, p-JNK and Bax/Bcl-2 ratio was not attenuated, while SHP overexpression and FXR ligand inhibited expression of these proteins in cisplatin-pretreated HK2 cells. In conclusion, FXR ligand, 6ECDCA prevents cisplatin-induced kidney injury, the underlying mechanism of which may be associated with anti-fibrotic, anti-inflammatory, and anti-apoptotic effects through SHP induction.
Decoding Target Distance and Saccade Amplitude from Population Activity in the Macaque Lateral Intraparietal Area (LIP)

Primates perform saccadic eye movements in order to bring the image of an interesting target onto the fovea. Compared to stationary targets, saccades toward moving targets are computationally more demanding since the oculomotor system must use speed and direction information about the target as well as knowledge about its own processing latency to program an adequate, predictive saccade vector. In monkeys, different brain regions have been implicated in the control of voluntary saccades, among them the lateral intraparietal area (LIP). Here we asked, if activity in area LIP reflects the distance between fovea and saccade target, or the amplitude of an upcoming saccade, or both. We recorded single unit activity in area LIP of two macaque monkeys. First, we determined for each neuron its preferred saccade direction. Then, monkeys performed visually guided saccades along the preferred direction toward either stationary or moving targets in pseudo-randomized order. LIP population activity allowed to decode both, the distance between fovea and saccade target as well as the size of an upcoming saccade. Previous work has shown comparable results for saccade direction (Graf and Andersen, 2014a,b). Hence, LIP population activity allows to predict any two-dimensional saccade vector. Functional equivalents of macaque area LIP have been identified in humans. Accordingly, our results provide further support for the concept of activity from area LIP as neural basis for the control of an oculomotor brain-machine interface.
The OPFET: A new high speed optical detector

A sensitive, high speed optical detector is needed for use in optical communications as well as for laboratory experiments. Recent experiments (1) have shown the GaAs MESFET to be potentially useful as a fast optical detector. We call this device an OPFET. This report summarizes new experimental results which show that the OPFET is both fast and sensitive and which identify the detection mechanism in this structure as photoconductivity. Calculations show that this device should give performance which exceeds that of PIN photo-diodes and rivals avalanche photodiodes. In addition, the structure is easy to integrate for use in optical circuits.
Employment Dynamics and the Structure of Labor Adjustment Costs

In this article we document the patterns of employment adjustment at the micro level. We find clear evidence of lumpy adjustment consistent with the presence of nonconvexities in the adjustment technology—inaction is pervasive, action spells are short‐lived, and extreme adjustment episodes are responsible for a nontrivial share of employment adjustment. We also find that the probability of employment adjustment increases with the duration of inaction. The skill structure of the workforce, the type of employment contract, and the proportion of low‐tenure workers, which we interpret as proxies for the magnitude of adjustment costs, all influence the probability of adjustment.
Classified stable matching

We introduce the classified stable matching problem, a problem motivated by academic hiring. Suppose that a number of institutes are hiring faculty members from a pool of applicants. Both institutes and applicants have preferences over the other side. An institute classifies the applicants based on their research areas (or any other criterion), and, for each class, it sets a lower bound and an upper bound on the number of applicants it would hire in that class. The objective is to find a stable matching from which no group of participants has reason to deviate. Moreover, the matching should respect the upper/lower bounds of the classes. In the first part of the paper, we study classified stable matching problems whose classifications belong to a fixed set of "order types. " We show that if the set consists entirely of downward forests, there is a polynomial-time algorithm; otherwise, it is NP-complete to decide the existence of a stable matching. In the second part, we investigate the problem using a polyhedral approach. Suppose that all classifications are laminar families and there is no lower bound. We propose a set of linear inequalities to describe stable matching polytope and prove that it is integral. This integrality result allows us to find optimal stable matchings in polynomial time using Ellipsoid algorithm; furthermore, it gives a description of the stable matching polytope for the many-to-many (unclassified) stable matching problem, thereby answering an open question posed by Sethuraman, Teo and Qian.
Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model

Background Mutations in the gene encoding the E3 ubiquitin ligase parkin (PARK2) are responsible for the majority of autosomal recessive parkinsonism. Similarly to other knockout mouse models of PD-associated genes, parkin knockout mice do not show a substantial neuropathological or behavioral phenotype, while loss of parkin in Drosophila melanogaster leads to a severe phenotype, including reduced lifespan, apoptotic flight muscle degeneration and male sterility. In order to study the function of parkin in more detail and to address possible differences in its role in different species, we chose Danio rerio as a different vertebrate model system. Methodology/Principal Findings We first cloned zebrafish parkin to compare its biochemical and functional aspects with that of human parkin. By using an antisense knockdown strategy we generated a zebrafish model of parkin deficiency (knockdown efficiency between 50% and 60%) and found that the transient knockdown of parkin does not cause morphological or behavioral alterations. Specifically, we did not observe a loss of dopaminergic neurons in parkin-deficient zebrafish. In addition, we established transgenic zebrafish lines stably expressing parkin by using a Gal4/UAS-based bidirectional expression system. While parkin-deficient zebrafish are more vulnerable to proteotoxicity, increased parkin expression protected transgenic zebrafish from cell death induced by proteotoxic stress. Conclusions/Significance Similarly to human parkin, zebrafish parkin is a stress-responsive protein which protects cells from stress-induced cell death. Our transgenic zebrafish model is a novel tool to characterize the protective capacity of parkin in vivo.
Animal Violence Demystified

Violence has been observed in humans and animals alike, indicating its evolutionary/biological significance. However, violence in animals has often been confounded with functional forms of aggressive behavior. Currently, violence in animals is identified primarily as either a quantitative behavior (an escalated, pathological and abnormal form of aggression characterized primarily by short attack latencies, and prolonged and frequent harm-oriented conflict behaviors) or a qualitative one (characterized by attack bites aimed at vulnerable parts of the opponent's body and context independent attacks regardless of the environment or the sex and type of the opponent). Identification of an operational definition for violence thus not only helps in understanding its potential differences from adaptive forms of aggression but also in the selection of appropriate animal models for both. We address this issue theoretically by drawing parallels from research on aggression and appeasement in humans and other animals. We also provide empirical evidences for violence in mice selected for high aggression by comparing our findings with other currently available potentially violent rodent models. The following violence-specific features namely (1) Display of low levels of pre-escalatory/ritualistic behaviors. (2) Immediate and escalated offense durations with low withdrawal rates despite the opponent's submissive supine and crouching/defeat postures. (3) Context independent indiscriminate attacks aimed at familiar/unfamiliar females, anaesthetized males and opponents and in neutral environments. (4) Orientation of attack-bites toward vulnerable body parts of the opponent resulting in severe wounding. (5) Low prefrontal serotonin (5-HT) levels upon repeated aggression. (6) Low basal heart rates and hyporesponsive hypothalamus–pituitary–adrenocortical (HPA) axis were identified uniquely in the short attack latency (SAL) mice suggesting a qualitative difference between violence and adaptive aggression in animals.
On the performance analysis of a satellite-based AIS system

This paper presents the performance analysis and system trade-offs of a satellite-based AIS (Automatic Identification System) system. Such a system represents a global monitoring extension of the current terrestrial AIS for ship identification and localization and is being currently investigated by several commercial and governmental entities. Operation of a constellation of LEO satellites targeting AIS detection is currently foreseen to be started within the next few years. In this paper, the feasibility of the concept is proven by deriving the probability of ship detection over key geographical areas like the North Atlantic Ocean. Key system and sub-system parameters and components are analyzed including the satellite orbit, the satellite antenna design and the on-board receiver. Their impact to the overall system performance is presented.
Lipoteichoic acids in Lactobacillus strains that colonize the mouse gastric epithelium

Extracts of cells of 22 strains of Lactobacillus species, and of fluids from cultures in a defined medium of two of the strains, were assayed by hemagglutination inhibition for lipoteichoic acids. A total of 10 of the preparations gave positive tests for the acids, including those from eight strains known to adhere to the keratinized squamous epithelium of the mouse stomach. These findings are consistent with an hypothesis that lactobacilli colonize the epithelial surface via adhesive interaction with the keratinized cells mediated by macromolecular complexes containing lipoteichoic acids.
Persistent Hepatic Structural Alterations Following Nanoceria Vascular Infusion in the Rat

Understanding the long-term effects and possible toxicity of nanoceria, a widely utilized commercial metal oxide, is of particular importance as it is poised for development as a therapeutic agent based on its autocatalytic redox behavior. We show here evidence of acute and subacute adverse hepatic responses, after a single infusion of an aqueous dispersion of 85 mg/kg, 30 nm nanoceria into Sprague Dawley rats. Light and electron microscopic evidence of avid uptake of nanoceria by Kupffer cells was detected as early as 1 hr after infusion. Biopersistent nanoceria stimulated cluster of differentiation 3+ lymphocyte proliferation that intermingled with nanoceria-containing Kupffer cells to form granulomata that were observed between days 30 and 90. Ultrastructural tracking of ceria nanoparticles revealed aggregated nanoceria in phagolysosomes. An increased formation of small nanoceria over time observed in the latter suggests possible dissolution and precipitation of nanoceria. However, the pathway for nanoceria metabolism/secretion remains unclear. Although frank hepatic necrosis was not observed, the retention of nanoceria increased hepatic apoptosis acutely, this persisted to day 90. These findings, together with our earlier reports of 5-nm ceria-induced liver toxicity, provide additional guidance for nanoceria development as a therapeutic agent and for its risk assessment.
Shorter Men Live Longer: Association of Height with Longevity and FOXO3 Genotype in American Men of Japanese Ancestry

Objectives To determine the relation between height, FOXO3 genotype and age of death in humans. Methods Observational study of 8,003 American men of Japanese ancestry from the Honolulu Heart Program/Honolulu-Asia Aging Study (HHP/HAAS), a genetically and culturally homogeneous cohort followed for over 40 years. A Cox regression model with age as the time scale, stratified by year of birth, was used to estimate the effect of baseline height on mortality during follow-up. An analysis of height and longevity-associated variants of the key regulatory gene in the insulin/IGF-1 signaling (IIS) pathway, FOXO3, was performed in a HHP-HAAS subpopulation. A study of fasting insulin level and height was conducted in another HHP-HAAS subpopulation. Results A positive association was found between baseline height and all-cause mortality (RR = 1.007; 95% CI 1.003–1.011; P = 0.002) over the follow-up period. Adjustments for possible confounding variables reduced this association only slightly (RR = 1.006; 95% CI 1.002–1.010; P = 0.007). In addition, height was positively associated with all cancer mortality and mortality from cancer unrelated to smoking. A Cox regression model with time-dependent covariates showed that relative risk for baseline height on mortality increased as the population aged. Comparison of genotypes of a longevity-associated single nucleotide polymorphism in FOXO3 showed that the longevity allele was inversely associated with height. This finding was consistent with prior findings in model organisms of aging. Height was also positively associated with fasting blood insulin level, a risk factor for mortality. Regression analysis of fasting insulin level (mIU/L) on height (cm) adjusting for the age both data were collected yielded a regression coefficient of 0.26 (95% CI 0.10–0.42; P = 0.001). Conclusion Height in mid-life is positively associated with mortality, with shorter stature predicting longer lifespan. Height was, moreover, associated with fasting insulin level and the longevity genotype of FOXO3, consistent with a mechanistic role for the IIS pathway.