Miracle-dz/UniFAR-FTUs huggingface dataset:
[Oral health of school children in Ceuta. Influences of age, sex, ethnic background and socioeconomic level].

BACKGROUND The objective of this study is that of gauging the prevalence of dental caries, periodontal disease and malocclusion among the school-age population of Ceuta and the spread thereof by age, sex, ethnic background and father's occupation. METHODS Prevalence survey of a multistage, stratified, random sample of schoolchildren 7, 12 and 14 years of age (n = 347) in order to calculate DMFT and dmft indexes--permanent and deciduous dentition--, CPITN and malocclusion. Assessment of the statistical significance of the differences encountered according to age, sex, ethnic background and socioeconomic status using the Chi-Square, Student T and Snedecor F tests. To calculate, among schoolchildren ages 12 and 14, the odds ratios of showing a DMFT index over 4 and their 95% confidence intervals by gender, ethnic background and the socioeconomic status. RESULTS Dmft (decayed, filled and missing teeth) was 3.02 at 7 and DMFT was 3.91 at 12 and 4.46 at 14. Odds ratios of DMFT > 4 were 2.26 by gender (95% CI = 1.27-4.05), 2.17 by ethnic group (95% CI = 1.18-3.99) and 1.8 by SES (95% CI = 0.85-3.81). In schoolchildren of low SES--unemployed father's--OR by ethnic group was 1.37 (95% CI = 0.28-7.0). No statistically significant differences were found in the distribution of malocclusion and periodontal disease--except by age. CONCLUSIONS Dmft and DMFT values are in Ceuta higher than the mean national values and the proposed value of the WHO for the year 2000. Risk of DMFT higher than the median is 2.3 in girls compared with boys, 2.17 in Moslem compared with non Moslem and 1.8 in low SES schoolchildren--unemployed father's--compared to other SES schoolchildren. The increased risk related to ethnic background is influenced by SES.
Poly[ADP-Ribose] Polymerase-1 Expression Is Related To Cold Ischemia, Acute Tubular Necrosis, and Delayed Renal Function In Kidney Transplantation

Cold ischemia time especially impacts on outcomes of expanded-criteria donor (ECD) transplantation. Ischemia-reperfusion (IR) injury produces excessive poly[ADP-Ribose] Polymerase-1 (PARP-1) activation. The present study explored the hypothesis that increased tubular expression of PARP-1 contributes to delayed renal function in suboptimal ECD kidney allografts and in non-ECD allografts that develop posttransplant acute tubular necrosis (ATN). Materials and Methods Nuclear PARP-1 immunohistochemical expression was studied in 326 paraffin-embedded renal allograft biopsies (193 with different degrees of ATN and 133 controls) and in murine Parp-1 knockout model of IR injury. Results PARP-1 expression showed a significant relationship with cold ischemia time (r coefficient = 0.603), time to effective diuresis (r = 0.770), serum creatinine levels at biopsy (r = 0.649), and degree of ATN (r = 0.810) (p = 0.001, Pearson test). In the murine IR model, western blot showed an increase in PARP-1 that was blocked by Parp-1 inhibitor. Immunohistochemical study of PARP-1 in kidney allograft biopsies would allow early detection of possible delayed renal function, and the administration of PARP-1 inhibitors may offer a therapeutic option to reduce damage from IR in donor kidneys by preventing or minimizing ATN. In summary, these results suggest a pivotal role for PARP-1 in the ATN of renal transplantation. We propose the immunohistochemical assessment of PARP-1 in kidney allograft biopsies for early detection of a possible delayed renal function.
On optimal real-time subsystem-interface generation in the presence of shared resources

The Hierarchical Scheduling Framework (HSF) has been introduced as a design-time framework enabling compositional schedulability analysis of embedded software systems with real-time properties. However, supporting resource sharing in HSF is a major challenge, since it increases the amount of CPU resources required to guarantee schedulability of the hard real time tasks, and it decreases the composability at the system level. In this paper, we focus on a compositional framework called the bounded-delay resource open environment (BROE) server, and we identify key parameters of this framework that have a great effect on how the framework will utilize CPU resources. In addition, we show how to select optimal values for these parameters in order to reduce the required CPU resource.
Blood microRNAs in Low or No Risk Ischemic Stroke Patients

Ischemic stroke is a multi-factorial disease where some patients present themselves with little or no risk factors. Blood microRNA expression profiles are becoming useful in the diagnosis and prognosis of human diseases. We therefore investigated the blood microRNA profiles in young stroke patients who presented with minimal or absence of risk factors for stroke such as type 2 diabetes, dyslipidemia and hypertension. Blood microRNA profiles from these patients varied with stroke subtypes as well as different functional outcomes (based on modified Rankin Score). These microRNAs have been shown to target genes that are involved in stroke pathogenesis. The findings from our study suggest that molecular mechanisms in stroke pathogenesis involving low or no risk ischemic stroke patients could differ substantially from those with pre-existing risk factors.
Densification: Semantic document analysis using Wikipedia

Abstract This paper proposes a new method for semantic document analysis: densification, which identifies and ranks Wikipedia pages relevant to a given document. Although there are similarities with established tasks such as wikification and entity linking, the method does not aim for strict disambiguation of named entity mentions. Instead, densification uses existing links to rank additional articles that are relevant to the document, a form of explicit semantic indexing that enables higher-level semantic retrieval procedures that can be beneficial for a wide range of NLP applications. Because a gold standard for densification evaluation does not exist, a study is carried out to investigate the level of agreement achievable by humans, which questions the feasibility of creating an annotated data set. As a result, a semi-supervised approach is employed to develop a two-stage densification system: filtering unlikely candidate links and then ranking the remaining links. In a first evaluation experiment, Wikipedia articles are used to automatically estimate the performance in terms of recall. Results show that the proposed densification approach outperforms several wikification systems. A second experiment measures the impact of integrating the links predicted by the densification system into a semantic question answering (QA) system that relies on Wikipedia links to answer complex questions. Densification enables the QA system to find twice as many additional answers than when using a state-of-the-art wikification system.
The ACS Virgo Cluster Survey. IV. Data Reduction Procedures for Surface Brightness Fluctuation Measurements with the Advanced Camera for Surveys

The Advanced Camera for Surveys (ACS) Virgo Cluster Survey is a large program to image 100 early-type Virgo galaxies using the F475W and F850LP bandpasses of the Wide Field Channel of the ACS instrument on the Hubble Space Telescope (HST). The scientific goals of this survey include an exploration of the three-dimensional structure of the Virgo Cluster and a critical examination of the usefulness of the globular cluster luminosity function as a distance indicator. Both of these issues require accurate distances for the full sample of 100 program galaxies. In this paper, we describe our data reduction procedures and examine the feasibility of accurate distance measurements using the method of surface brightness fluctuations (SBF) applied to the ACS Virgo Cluster Survey F850LP imaging. The ACS exhibits significant geometrical distortions owing to its off-axis location in the HST focal plane; correcting for these distortions by resampling the pixel values onto an undistorted frame results in pixel correlations that depend on the nature of the interpolation kernel used for the resampling. This poses a major challenge for the SBF technique, which normally assumes a flat power spectrum for the noise. We investigate a number of different interpolation kernels and show through an analysis of simulated galaxy images having realistic noise properties that it is possible, depending on the kernel, to measure SBF distances using distortion-corrected ACS images without introducing significant additional error from the resampling. We conclude by showing examples of real image power spectra from our survey.
Health Implications of a 5 Mm Hg Increase in Blood Pressure

The health implications of a mean increase in blood pressure on the order of 5 mm Hg among young persons are explored primarily from a public health point of view. After an overview of the epidemiologic behavior of human blood pressure is provided, the phenomenon of "tracking" of blood pressure is examined as is the possible relationship between the rate of blood pressure change over time and the initial value. In the last part of the paper, the community benefits of lowering the average blood pressure 5 mm Hg (in terms of number of heart attacks prevented) are estimated under several simplifying assumptions.
Signaling in neuropeptide‐induced migration of human eosinophils

At inflammatory sites, leukocytes may confront multiple, competing chemoattractive signals. We compared the chemotactic potencies of several sensory neuropeptides with regard to signal transduction pathways in eosinophils. Eosinophils were enriched using magnetic cell sorting and migration was assayed in a Boyden microchemotaxis chamber. We found stimulatory effects of substance P, calcitonin gene‐related peptide (CGRP), secretoneurin, vasoactive intestinal peptide (VIP), and secretin on eosinophil migration. Actions of VIP are predominantly mediated via VIP receptor type I. Migration toward secretoneurin, VIP, and secretin was blocked by a phosphodiesterase inhibitor, which, in contrast failed to affect substance P‐ and CGRP‐induced eosinophil chemotaxis. Wortmannin blunted the migratory responses induced by all neuropeptides tested and substance P‐induced effects on eosinophils were tyrphostin‐23‐sensitive. We conclude that substance P, CGRP, secretoneurin, and VIP/secretin stimulate eosinophil migration involving wortmannin‐sensitive enzymes. Moreover, secretoneurin and VIP/secretin require additional activation of phosphodiesterases to stimulate eosinophil migration. J. Leukoc. Biol. 64:828–834; 1998.
Myeloid Proliferation without GATA1 Mutations in a Fetus with Down Syndrome Presenting in Utero as a Pericardial Effusion

An isolated pericardial effusion was observed during a routine prenatal ultrasound in a fetus of 30 and 3/7 weeks gestation. Amniocentesis was performed and revealed a trisomy 21. After prenatal counseling, the parents opted for termination of the pregnancy at 32 weeks. Postmortem examination confirmed the presence of a pericardial effusion, without structural cardiac anomalies, and showed the development of ascites and subcutaneous edema. Histological examination showed an infiltrate of megakaryoblasts and irregular, dysplastic megakaryocytes confined to the epicardium, the pericardial lymph nodes, and the pancreas, consistent with a myeloid proliferation related to Down syndrome. Sequencing of exons 2 and 3 of the GATA1 gene from the umbilical cord blood and from megakaryoblast infiltrate showed no mutation. A high incidence of chromosomal abnormalities, in particular trisomy 21, has been described in fetuses with pericardial effusion. However, myeloid proliferation related to Down syndrome without GATA1 mutations is extremely rare. To our knowledge, only one such case has been reported to date. We present here a 2nd case, which further supports the hypothesis that hyperproliferation of megakaryocytes in a subset of Down syndrome patients may be initiated by events other than GATA1 mutations.
Advanced Focus Group Research

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Suprachiasmatic Nuclei Grafts Restore the Circadian Rhythm in the Paraventricular Nucleus of the Hypothalamus

The mammalian suprachiasmatic nucleus (SCN) controls the circadian rhythm of many physiological and behavioral events by an orchestrated output of the electrical activity of SCN neurons. We examined the propagation of output signals from the SCN into the hypothalamus, especially into the region of the paraventricular nucleus, through multimicroelectrode recordings using acute and organotypic brain slices. Circadian rhythms in spontaneous firing rate with a period close to 24 hr were demonstrated in the SCN, in directly adjacent hypothalamic regions, and in the region of the paraventricular nucleus of the hypothalamus, an important center for the integration of neuroendocrine, homeostatic, and autonomic functions. The activity rhythms recorded from structures outside of the SCN were in phase with the rhythms in the SCN. Cyclic information in the hypothalamus was lost after ablation of the SCN but could be restored by SCN grafts, indicating that a humoral factor is responsible for the restoration of circadian rhythmicity in the absence of neural connections. Periodic application of arginine–vasopressin (AVP) provided evidence that AVP can induce rhythmicity in the hypothalamus. These data indicate that the SCN uses a dual (neuronal and humoral) mechanism for communication with its targets in the brain.
Customer satisfaction with game and service experiences: antecedents and consequences.

Sport marketing researchers have generally studied two types of satisfaction at sporting events: game satisfaction and service satisfaction. One gap in the literature is studying the two types together. A model of the relationships between service quality, core product quality, game and service satisfaction, and behavioral intentions is proposed and tested. Data were collected from spectators at a professional baseball game in Japan (n = 283) and at two college football games in the United States (n = 343). The results in both Japan and the United States indicate that game atmosphere was a strong predictor of game satisfaction whereas stadium employees and facility access were the major antecedents of service satisfaction. Game satisfaction had a significant impact on behavioral intentions across the two settings, although the service satisfaction-behavioral intentions relationship was significant only in Japan. The research findings, managerial implications, limitations, and directions for future researc.
Collaborative planning forecasting and replenishment: new solutions needed for mass collaboration

The challenge faced by supplier companies in the grocery supply chain for implementing collaborative planning, forecasting and replenishment (CPFR) is how to get the retailer to forecast, especially when it has not been necessary before. In this paper a solution that would allow collaboration on a wide scale is presented. The forecasting approach is called ``rank and share’’ and uses input from the retailer’s existing planning process ± the category management process. The benefit of using category management as the basis is that the retailer can scale up collaboration with a large number of suppliers without increasing planning resources. For the supplier the benefit is point of sales forecasts at the time of the assortment decision. To support this collaborative forecasting process there is a need for more robust replenishment solutions, new measures to illustrate benefits, and for a distributed planning architecture and software. Potential solutions for these are also discussed in the paper.
Happy animals make good science

In this paper the question is posed whether it is not only better for the animal to be happy, but whether its state of mind may also have the potential to influence the scientific results derived from it. To ensure good science, the animal should have a normal physiology and behaviour, apart from specific adverse effects under investigation. There is a growing body of evidence from a wide variety of sources to show that animals whose well-being is compromised are often physiologically and immunologically abnormal and that experiments using them may reach unreliable conclusions. On scientific, as well as ethical grounds, therefore, the psychological well-being of laboratory animals should be an important concern for veterinarians, animal technicians and scientists.
Settling Properties of Activated Sludge from a Sequencing Batch Reactor (SBR)

The purpose of this work was to examine the settling properties of activated sludge from a sequencing batch reactor (SBR). The experiments were carried out in a bench-scale reactor, fed with wastewater from the University of Olsztyn treatment plant. Concentrations of the examined activated sludge varied between 2.5 and 6.0 kg SS m -3 . Laboratory analyses of the sludge comprised: sludge concentration, settleability, sedimentation velocity and sludge volume index (SVI). The study revealed very good settling properties of the sludge. Low SVI (30 - 60 ml g -1 SS) was responsible for an intensive and quick sedimentation which shortened the settle phase to less than one hour. Moreover, low SVI prevented the sludge from bulking. High dissolved oxygen concentrations in the aeration tank during the react phase resulted in little sludge biomass growth, which is very important from the viewpoint of sludge disposal at a wastewater treatment plant.
The Industrial Ecology of Lead and Electric Vehicles

The lead battery has the potential to become one of the first examples of a hazardous product managed in an environmentally acceptable fashion. The tools of industrial ecology are helpful in identifying the key criteria that an ideal lead‐battery recycling system must meet maximal recovery of batteries after use, minimal export of used batteries to countries where environmental controls are weak, minimal impact on the health of communities near lead‐processing facilities, and maximal worker protection from lead exposure in these facilities. A well‐known risk analysis of electric vehicles is misguided, because it treats lead batteries and lead additives in gasoline on the same footing and implies that the lead battery should be abandoned. The use of lead additives in gasoline is a dissipative use where emissions cannot be confined: the goal of management should be and has been to phase out this use. The use of lead in batteries is a recyclable use, because the lead remains confined during cycles of discharge and recharge. Here, the goal should be clean recycling. The likelihood that the lead battery will provide peaking power for several kinds of hybrid vehicles‐a role only recently identified increases the importance of understanding the levels of performance achieved and achievable in battery recycling. A management system closely approaching clean recycling should be achievable.
Monitoring cell-cell contacts in vivo in transgenic animals

We used a synthetic genetic system based on ligand-induced intramembrane proteolysis to monitor cell-cell contacts in animals. Upon ligand-receptor interaction in sites of cell-cell contact, the transmembrane domain of an engineered receptor is cleaved by intramembrane proteolysis and releases a protein fragment that regulates transcription in the interacting partners. We demonstrate that the system can be used to regulate gene expression between interacting cells, both in vitro and in vivo, in transgenic Drosophila. We show that the system allows for detection of interactions between neurons and glia in the Drosophila nervous system. In addition, we observed that when the ligand is expressed in subsets of neurons with a restricted localization in the brain it leads to activation of transcription in a selected set of glial cells that interact with those neurons. This system will be useful to monitor cell-cell interactions in animals, and can be used to genetically manipulate cells that interact with one another. Summary: A synthetic genetic system is used to monitor cell-cell contacts in animals, to genetically manipulate interacting cells, and to investigate the connectivity of neurons in brain circuits.
Utilization of potato peels and sugar beet pulp with and without enzyme supplementation in broiler chicken diets: effects on performance, serum biochemical indices and carcass traits

This study was conducted to investigate the effects of including potato peels (PP) and sugar beet pulp (SBP), as unconventional feeds, with and without enzyme in broiler diets from 1 to 42 days of age by observing the growth performance, blood parameters and carcass characteristics. A total of 150, 1-day old, chicks were randomly assigned into five groups, each with 30 chicks. Birds in group 1 were fed on the control diet. Chicks in groups 2 and 3 were offered diets containing PP and SBP at the rate of 15% and 7.5%, respectively, while those in groups 4 and 5 were fed the same diets but with adding an enzyme mixture. Using the unconventional feeds in the diets was found to decrease the body weight (BW). However, the feed intake, weight gain and feed conversion did not differ from the control in PP at the grower period, but decreased in SBP throughout the experiment. Addition of enzyme greatly improved the BW in PP and SBP to a degree that it surpasses the control and also increased the feed intake and conversion. The total cholesterol and low-density lipoprotein cholesterol serum levels were decreased in all tested groups. Carcass yield was not affected by treatments, but the carcass fat content was reduced using the unconventional feeds with or without enzyme. In conclusion, PP can be used at a rate of 15% in the grower diets of broilers. Furthermore, 15% PP or 7.5% SBP can be included in starter and grower diets, but with the addition of enzymes. This can help in solving the problem of current shortage and rising costs of conventional feeds.
GSIS: A Secure and Privacy-Preserving Protocol for Vehicular Communications

In this paper, we first identify some unique design requirements in the aspects of security and privacy preservation for communications between different communication devices in vehicular ad hoc networks. We then propose a secure and privacy-preserving protocol based on group signature and identity (ID)-based signature techniques. We demonstrate that the proposed protocol cannot only guarantee the requirements of security and privacy but can also provide the desired traceability of each vehicle in the case where the ID of the message sender has to be revealed by the authority for any dispute event. Extensive simulation is conducted to verify the efficiency, effectiveness, and applicability of the proposed protocol in various application scenarios under different road systems.