Question: What handgun cartridge designed by John Browning in 1905, for use in his prototype Colt semi-automatic pistol, is chambered in a third-generation semi-automatic pistol from Smith & Wesson's 4500 series of handguns?
Sentence (from ".45 ACP"): The .45 ACP (Automatic Colt Pistol), or .45 Auto (11.43×23mm) is a handgun cartridge designed by John Browning in 1905, for use in his prototype Colt semi-automatic pistol.
Relevant evidence: Yes