Question: Sana Saeed made her screen debut as an adult in a film directed by a man informally referred to by what nickname?
Sentence (from "Karan Johar"): Karan Johar (born 25 May 1972), often informally referred to as KJo, is an Indian film director, producer, screenwriter, costume designer, actor and television personality who is primarily known for his work in Hindi films.
Relevant evidence: Yes