Question:  Which university, classified as a Research University with very high research activity (RU/VH) by the Carnegie Foundation for the Advancement of Teaching, is The Gilmour B. and Edith Craig MacDonald House is a historic building located?
Sentence (from "Iowa State University"): It is the largest university in the state of Iowa and the 3rd largest university in the Big 12 athletic conference.
Relevant evidence: No