Question: When was Isabella Of Portugal's husband born?
Sentence (from "Charles V, Holy Roman Emperor"): Charles V (24 February 1500 – 21 September 1558) was Holy Roman Emperor and Archduke of Austria from 1519, King of Spain (Castile and Aragon, as Charles I) from 1516, and Lord of the Netherlands as titular Duke of Burgundy from 1506.
Relevant evidence: Yes