Question: Who is the paternal grandmother of João Manuel, Prince Of Portugal?
Sentence (from "João Manuel, Prince of Portugal"): João Manuel, Prince of Portugal  (3 June 1537 – 2 January 1554) was a Portuguese "infante" (prince), the eighth son of King John III of Portugal by his wife Catherine of Austria, daughter of Philip I of Castile and Joanna of Castile.
Relevant evidence: Yes