Question: What is the title of a 2002 American animated science fiction comedy-drama film with an illegally-made, genetically-engineered, extraterrestrial lifeform resembling a blue koala and his adopter and best friend who is also its primary protagonist? 
Sentence (from "Treasure Planet"): The film employs a novel technique of hand-drawn 2D traditional animation set atop 3D computer animation.
Relevant evidence: No