definiens: shall mean the THERAPEUTIC FIELD OF USE, the THERANOSTIC FIELD OF USE, or the INTERNAL RESEARCH FIELD OF USE, where such FIEL DS are further defined as : A. means the use of genetically modified prokaryotic organisms to treat and/or prevent disease, disorders and/or conditions by : ( 1 ) in vivo delivery of such prokaryotic organisms to a subject ; or ( 2 ) treatment of a subject ’s sample by ex vivo c ontact with such genetically modified prokaryotic o rganisms coupled with a subsequent in vivo delivery to said subject of at least a portion of the treated sample or by - product thereof, and for the avoidance of any doubt expressly excludes : ( a ) the use of such genetically modified prokaryoti c organisms to manufacture biologic agents ( e.g., peptide, protein, antibody or nucleic acid ) for com mercialization ; ( b ) any manufacture ( including making, having made, using selling, offering for sale or importing ) of diagnostic products using genetically modified prok aryotic organisms ; ( c ) any exclusive right to conduct research and/or development ; and ( d ) any right to exclude others from the manufactur e ( make and have made ), use, sale, offer for sale o r importation of RESEARCH TOOLS . For the avoidance of doubt, this Section 1.5(A)(d ) shall not limit COMPANY ’s ability to exclusively practice the PATEN T RIGHTS in the FIELDS licensed hereunder