definiens: means all Know - How Controlled by [COMPANY] or its Affiliates on the Effective Date or at any time during theAgreement Term necessary to Research, Develop or Commercialize a Product or disclosed by [COMPANY] to [COMPANY] and specifically relating to(i ) the composition of matter of a Product or ( ii ) methods of using a Product as a prophylactic or therapeutic ; provided however, Know - HowControlled by [COMPANY] or any of its Affiliates that ( y ) consists of subject matter applicable to oligonucleotide compounds or products in general or(z ) relates to an oligonucleotide compound that does not specifically modulate expression of DNM2 via the binding, partially or wholly, of suchcompound to RNA that encodes DNM2, will not be considered [COMPANY] Product- Specific Know - How, and in the case of ( y ) and ( z ), suchKnow - How will be considered [COMPANY] Core Technology Know - How