definiens: means all Patent Rights Controlled by Eyetech or its Affiliates as of the Restatement Date relating to, or useful in connection with, the manufacture, use or sale of the Compound or the Product in the ROW Territory, including the patents and patent applications set forth on Schedule 1.21 . Any patentable inventions that have been reduced to practice prior to the Restatement Date for which a patent application is not filed until after the Restatement Date shal1 be included within the definition of Eyetech Patent Rights . ~or the -1 avoidance of doubt, PCT applications PCT fUS2004/025422(EYE12 ), PCTfUS2004/027612 ( EYEl3 ), PCTfUS2006/029503 ( EYE34 ), and PCTfUS2006/45887 ( EYE38 ), and all related Patent Rights are not included within the Eyetech Patent Rights