definiens: ), defined as the actual stripsproduced before samples divided by the theoretical strips available based on the amount of defect free APIused in manufacturing . For the avoidance of doubt, this includes any API dispensed and/or used forcommercial production regardless of whether film strips were yielded from said use but excluding APIassociated with batches destroyed based on Visual Sampling data . The parties will work in good faith toidentify commercially reasonable Yield Targets for dosage strengths, batch sizes, and SKU configurationswithin ninety ( 90 ) days of the Amendment Effective Date . On an annual basis, MSX and RB will review andreconcile results against the Yield Target and MSX will, within thirty ( 30 ) days, remunerate RB for RB’sdocumented API costs on an annual basis to the extent MSX falls below the Yield Target . For the sake ofclarity, the formula for calculating API costs owed will be Yield Target minus the actual yield times the APIcosts . The parties hereby agree that Clause 3.4.3 of the Agreement represents the sole mechanism for MSXreimbursement of API to RB associated with manufacturing usage and waste