definiens: means, for any period, the gross am ount invoiced by Acer, its Sublicensees or any of its or their respective Affi liates for the sale of a Licensed Product ( the ), less deductions for : ( a ) normal and custom ary trade, quantity and cash discounts and sales returns and allowances ; ( b ) freight, postage, shipp ing and insurance expenses to the extent that such items are included in the gross amount invoiced ; ( c ) cust oms and excise duties and other duties related to t he sales to the extent that such items are included in the gross amount invoiced ; and ( d ) rebates and sim ilar payments made with respect to sales paid for by any governmental or regulatory authority, in each case ( ( a ) to ( d ) ) in accordance with GAAP . Any of the de ductions listed above that involves a payment by Ac er, its Sublicensees or any of its or their respective Affiliates shall be taken as a deduction in the Cal endar Quarter in which the payment is accrued by such ent ity . For purposes of determining Net Sales, a Licensed Product shall be deemed to be sold when in voiced and a shall not include transfers or dispositions of such Licensed Product for pre - clini cal or clinical purposes or as samples, in each cas e, without charge