definiens: ), subject to the Ceiling ( ( defined below).Notwithstanding any provision of this Agreement, in no event shall the sum of the following exceed US$ 7 million ( the ): ( a ) US$ 2.2 million ( representing the aggregate reduction in total milestone payments payable by ESPERION under Section 3.1 of this Agreement from US$ 8.75 million, as previously provided in Section 3.1 upon execution of this Agreement, to US$ 6.55 million, as provided in Section 3.1, as amended ) ; ( b ) the aggregate reduction in the amount of royalties paid by ESPERION to INEX based on Net Annual Sales in North America under Section 4.1(a ) of this Agreement, as amended, as compared with the amount of such royalties payable as previously provided in Section 4.1(a ) of this Agreement upon execution of this Agreement ; and ( c ) the aggregate Sublicensing Credits applied as a credit by ESPERION