definiens: means any small molecule compound that ( a ) [ * ] interacts with the PPAR - dreceptor to [ * ] or [ * ], and ( b ) shows activity toward [ * ] the PPAR - d receptor in the [ * ] assay using [ * ] ( or any [ * ] thereof ) . To constitute a Selective PPAR - d Modulator, the compound must not [ * ] ( i ) [ * ] or ( ii ) [ * ] . For the purposes ofclause ( i ) of this Section 1.27, means [ * ] in either the [ * ] and/or [ * ], as applicable, that is [ * ] obtained in the [ * ] assay . For the purposes of clause ( ii ) of this Section 1.27, means [ * ] of the [ * ] of the compound for the [ * ] ( measured at [ * ] determined in the [ * ] assay ) in the generally accepted assay for the [ * ] ( or if there is no suchgenerally accepted assay, a validated assay for the [ * ] ) . Notwithstanding the above, the term shall include, without limitation, [ * ]