definiens: shall mean the principal amount ( and any premium thereon ), plus accrued and unpaidinterest thereon and any fees and expenses and other amounts due, owed by Revance to Hercules Technology Growth Capital, Inc. ( ) pursuant to that certain Loan and Security Agreement, dated as of September 20, 2011, as amended, restated, supplemented or otherwise modified from time to time, and any documents related thereto ( the ) . IfRevance refinances or increases the amount of the Existing Hercules Debt, references herein to Existing Hercules Debt shallinclude the principal of ( and premium, if any ), unpaid interest on and amounts reimbursable, fees, expenses, and otheramounts due in connection with indebtedness for borrowed money of Revance, to banks, commercial finance lenders or otherlending institutions regularly engaged in the business of lending money, including Hercules Capital, in connection with suchrefinancing and any increase, extension, refinance, renewal, replacement, defeasance or refunding thereof ( each, a )