definiens: shall mean all Information and Material Controlled by [COMPANY] prior to or on the Effective Date necessary to Develop, manufactur e or Commercialize Licensed Products, including but not limited to the following information : ( 1 ) informati on disclosed in the IND for Alfimeprase as of the E ffective Date ; ( 2 ) information disclosed as of the Effective Date in any IND supplements for Alfimeprase ; ( 3 ) a ll [COMPANY] - sponsored collaborator data and results ( subject to any contractual confidentiality obligations of Amg en to Third Parties regarding such results ) ; ( 4 ) any regulatory data which [COMPANY] provides to [COMPANY] ; ( 5 ) sequence information of other Licensed Products and informat ion regarding their activity ; and ( 6 ) such informat ion which [COMPANY] expressly designates in writing it intends to include as [COMPANY] Know - How under this License Agreement ; provided however, that [COMPANY] Know - How sh all exclude [COMPANY] Material and Manufacturing Information