definiens: shall mean [ a Compound the primary pharmacological affinity and activity of which, and the primary utility of which as a pharmaceutical agent, is because such Compound binds to a CRFI Receptor or otherwise modulates the activity of such a receptor and elicits a phannacological response by antagonizing, CONFIDENTIA L TREA TM ENT REQUESTED PURSUANT TO 5 u.sc . § 552 and 17 C.F.R. § § 240.12(b)(4 ), 200.80 and 200.83 BY LETTER FROM MILBANK, TWEED, HADLEY & McCLOY LLP nATIOn MARrW?R ? nn ? - 8 -CONFIDENTIAL TREATMENT REQUESTED acting as an agonist . or otherwise altering a signal nonnally induced by a CRF Family Member in a cell . ]