definiens: means, the gross invoiced sales of a Product to al l customers less ( i ) the cost of the Product, including freight in, duty, customs, shipp ing and all related direct costs of acquiring the Product ; ( ii ) chargebacks ; ( iii ) freight and insura nce charges ; ( iv ) trade discounts, credits or allowances ; ( v ) costs of replacements, returns, rec alls or rebates ( including but not limited to group purchasing organization fees and rebates ) ; ( vi ) dis counts or rebates or other payments required by law to be made under Medicaid, Medicare or other go vernmental special medical assistance programs ( vii ) wholesaler service charges ; ( viii ) s ales, excise or value added taxes paid on or in relation to sales of the Product ; and ( ix ) [ * * * ], a s calculated in accordance with United States Generally Accepted Accounting Principles, or US GAA P