definiens: means any Know - How, invention or discovery ( and all Intellectual Propertyclaiming or covering such invention or discovery ) ( a ) conceived, discovered, or made in connection with this Agreement byeither Party ( or any Aﬃliate thereof ), solely or jointly with the other Party ( or any Aﬃliate thereof ) or ( b ) conceived, discovered, or made by or on behalf of Naia ( or any Aﬃliate thereof ) or any Sublicensee in the development orcommercialization of the Licensed Product or any Backup Molecule, in each of cases ( a ) and ( b ), whether patentable ornot, to the extent such Know - How, invention or discovery is ( i ) related solely to Amunix Background Technology concerningXTEN Sequences or ( ii ) ( 1 ) directly related to XTEN Sequences, but excluding modiﬁcations to Naia BackgroundTechnology or Naia Improvements for use with XTEN Sequences, and ( 2 ) severable from Naia Background Technology . Forpurposes of clarity, ( x ) Amunix Improvements includes ( I ) any and all derivative, modiﬁed, or truncated amino acid sequencecompositions of XTEN Sequences conceived, discovered, or made in connection with this Agreement by either Party ( or anyAﬃliate thereof ), solely or jointly with the other Party ( or any Aﬃliate thereof ), or any Sublicensee, ( II ) any XTENModiﬁcations conceived or discovered by either Party ( or any Aﬃliate thereof ), solely or jointly with the other Party ( or anyAﬃliate thereof ), or any Sublicensee as a result of Naia ’s, its Aﬃliate ’s, or Sublicensee ’s exercise of any rights granted byAmunix under this Agreement or knowledge of Amunix ’s Conﬁdential Information, or ( III ) methods of making such aminoacid sequence compositions conceived, discovered, or made in connection with this Agreement by either Party ( and in eachcase of clauses ( I ) – ( III ) all Intellectual Property claiming or covering such invention or discovery ) and, notwithstandinganything to the contrary, ( y ) Amunix Improvements do not include, to the extent conceived, generated, or invented by or onbehalf of Naia, any Aﬃliate thereof, or any Sublicensee, solely or jointly with Amunix, any Aﬃliate thereof, or any ThirdParty, any methods or uses for the treatment of indications or treatment regimens for Licensed Products or XTENSequences