definiens: means an aggregate gross amo unt of monies received by [COMPANY], [COMPANY] 's Licensee(s ), and/or Affiliates of [COMPANY], for the sale of Drug Product, provided, however, that sales between and among [COMPANY] and its Affiliates and [COMPANY] 's Licensee of Drug Product which are subsequently resold or to be resold by such Affiliates or [COMPANY] Lice nsees shall be excluded from the scope of Drug Product Revenue . In the case of a Combination Product for which the agent or ingredient constituting a CART I dentified Compound and each of the other active agents or ingredients not const ituting CART Identified Compounds have established market prices when sold separately, Drug Product Revenue shall be determined by multiplying the Drug Product Revenue for each such Combination Product by a fraction, the numerat or of which shall be the established market price for the Drug Product(s ) co ntained in the Combination Product and the denominator of which shall be the s um of the established market prices for the CART Identified Compound(s ) plus the other active agents or ingredients contained in the Combination Product . W hen such separate market prices are not established, then the parties shall negotiate in good faith to determine a fair and equitable method of calculatin g Drug Product Revenue in question