definiens: shall mean the level, type and quality of efforts that would be applied by a pharmaceutical company having resources and expertise similar to the applicable Party, to perform its obligations hereunder, with respect to a compound or product developed by such company, including its obligation to Develop, seek and obtain Regulatory Approval s for, manufacture and Commercialise the Product, all to the extent consistent with reasonable business practices, for example, in light of the reasonable commercial potential of the Product in the Territory . Without limiting the foregoing, Commercially Reasonable Best Efforts shall require that such Party : ( i ) devote appropriate resources and personnel with an appropriate level of education, experience and training for the performance of the relevant obligation ; ( ii ) promptly assign responsibility for the relevant obligation to specific individual s who are held accountable for progress and monitor such progress on an on - going basis, ( iii ) set and consistently seek to achieve specific and meaningful objectives and timelines for carrying out such obligation and ( iv ) compensate or otherwise incentivize such individual s in a manner and to an extent that is substantially similar, on the whole, to the compensation and incentives offered by such Party to similar individual s performing similar activities in comparable markets with respect to products of such Party having similar commercial potential to the Product