definiens: means all unpatented Know - How that ( i ) is owned or Controlled by [COMPANY] orits Affiliate as of the Effective Date of this Agreement, or owned or Controlled by [COMPANY] or its Affiliate thereafter during theCollaboration Term, and ( ii ) is necessary or useful for Licensed Antibody, and/or Licensed Product development and / orcommercialization ( including Know - How relating to any method of making, using ( including methods of administration anddosing regimens ) or testing of ( or in the case of testing, of or for the presence of ) or manufacturing of a Licensed Antibodyand / or Licensed Product ) or any article necessary or useful to practice ( including those present during the practice of any ofsuch method ) any of the foregoing ; but specifically excluding computational protein design methods and drug discovery ( butnot development ) methods and Know - How of an acquiror and/or the acquiring corporate family existing prior to or on thedate of a [COMPANY] Change of Control or independently of [COMPANY] thereafter ( for clarity, in the case where [COMPANY] is mergedinto another entity, the references here to and mean to refer to and )