definiens: shall mean the gross amount collected from sales of Products to an end - user, less ( i)trade, cash and quantity discounts actually allowed or paid ; ( ii ) credits, allowances and adjustmentsactually granted to customers ; ( iii ) charge back payments and rebates granted to managed careorganizations or to federal, state, local or foreign governments, their agencies, and purchasers andreimbursers or to trade customers, including, but not limited to, wholesalers and buying groups ; ( iv)separately itemized or allocated ( in direct proportion to the amount of sales of such Products bears tothe total amount of sales of all CBL products ) shipping costs, insurance or other transportation costs, tothe extent not paid or absorbed by non - Affiliate purchasers of such Products ; ( v ) sales, use and/or otherexcise taxes or duties actually paid ; and ( vi ) sales to Affiliates and/or Sublicensees for research anddevelopment purposes