definiens: means, when used to describe the relationship between an engineered human T cell an d a Target, that the T cell ( a ) is designed or being developed to bind to the Target ( or a portion there of ), ( b ) is designed or being developed to exert its biological effect in whole or in part through binding to such Target ( or such portion thereof ), and ( c ) is not designed or d eveloped to bind to or exert its effect on any othe r Target ( or a portion thereof ) . Notwithstanding the foregoing, wh en used to describe the relationship between an eng ineered human T cell and a Combination Target, means that the T cell ( i ) is designed or being de veloped to bind to both of the Targets ( or portions thereof ) t hat comprise the Combination Target, ( ii ) is design ed or being developed to exert its biological effect in whole o r in part through binding to both such Targets ( or such portions thereof ), and ( iii ) is not designed or developed to bind to or exert its effect on any other Target ( o r a portion thereof )