definiens: shall mean, on a Region - by - Region or one or moreMajor Market Countries basis ( determined based on the location of the applicable personnel ), therates agreed upon in local currency by the Parties at least twenty - four ( 24 ) months prior to theAnticipated First Commercial Sale in the Region or Major Market Country, as applicable, for eachcategory of field force personnel based upon the fully burdened cost of [ * * * ], of pharmaceuticalcompanies in the Field in the applicable country, and including an [ * * * ], such amount to beadjusted as of January 1 of each following Contract Year by the percentage increase ordecrease, if any, in the applicable CPI through June 30 of the prior10Certain portions of this Exhibit have been omitted pursuant to a request for confidentiality . Such omitted portions, which are marked with brackets and three asterisks [ * * * ], have been separately filed with the Commission