definiens: ( or ) means ( i ) for Collaboration Compounds Identified or Developed as part of the Research Collaboration, the date on which the JRC proposes a Collaboration Compound as a SoPD candidate molecule ( according to the criteria reflected in th e Research Plan attached as Appendix 1.94 ), provided that BI confirms the proposal by it s approval as an at the next senior BI management meeting where such pr oposal has been discussed, ( ii ) for other Development programs for which BI has final d ecision making authority, the date on which senior BI management approves a Compound as a SoPD candidate molecule ; ( iii ) for other Development programs for which Zeal and Pharma has final decision making authority, the date on which senior Zealand Pharma management approves a Compound for nomination, as defined in Zealand Pharma ’s product development procedures as of the Effective Date, attached hereto as Appendix 11.3, and ( iv ) in any event, if earlier, the start of a four ( 4 ) week GLP - toxicology study ( which study, for Collaboration Compounds, must have been approved by BI )