definiens: means activities, in compliance with all the applicableLaw, designed to ensure or improve appropriate medical use of, conduct medical educationregarding, or further research regarding, Tirasemtiv and the Product or to increase disease stateawareness, including by way of example : ( a ) activities of medical scientific liaisons, which shallmean the following functions : ( x ) conduct of service based medical activities including providinginput and assistance with consultancy meetings, recommending investigators for clinical trialsand providing input in the design of such trials and other research related activities, and ( y)delivery of non - promotional communications and conduct of non - promotional activities includingpresenting new clinical trial data and other scientific or disease state awareness information ; ( b)grants to support continuing medical education, symposia, or Third Party research related toProduct ; ( c ) development, publication and dissemination of publications relating to Tirasemtivand the Product and relevant disease states ; ( d ) medical information services provided inresponse to inquiries communicated via sales representatives or received by letter, phone call oremail ; ( e ) conducting advisory board meetings or other consultant programs ; ( f ) support ofinvestigator - initiated trials ; ( g ) managing relationships with cooperative groups, physician / hospital networks and disease state or patient and caregiver advocacy groups ; ( h)establishing and implementing risk, evaluation and mitigation strategies, ( i ) voluntary phase 4trials or post - approval patient registries, ( j ) health economic and outcomes research ( HEOR)activities, ( k ) independent medical education activities, and ( l ) non - promotional exhibiting atmedical and scientific fora . For the purposes of clarity, post - approval clinical studies within theapproved Indications, which were a condition for the receipt of Marketing Approval, shall beincluded within Development and shall not be included within Medical Affairs Activities