definiens: ), where such AdverseExperience is ( as defined hereinafter ) and associated with the clinical uses, studies, investigations, testsand marketing of such product, whether or not determined to be attributable to such product . as used in thisSection refers to an Adverse Experience which results in death, is immediately life threatening, results in persistentand significant disability / incapacity or requires in - patient hospitalization, or prolongation of existing hospitalization, oris a congenital anomaly, cancer or an overdose . Other important medical events that may jeopardize the patient ormay require intervention to prevent one of the outcomes previously listed should also be considered . If suchAdverse Experience is ( that is, it results in death or is immediately life threatening ), [COMPANY] willnotify [COMPANY] within [ * * ] . For Adverse Experiences that are Serious, but not Highly Serious, [COMPANY] will notifyGenentech within [ * * ]