definiens: means, w ith respect to a given Collaboration Undruggable Target, any drug Development program th at : ( a ) has, as one of its ultimate goals, the Devel opment of one ( 1 ) or more compounds or products that are Directed to such Undruggable Targ et using the Synthetic Lethal relationship between such Undruggable Target and the applicable Undruggable C ampaign Lesion(s ) that Repare has identified to [COMPANY] under this Agreement to define the patient populati on for such compound or product ; and ( b ) is initiated or continued by [COMPANY] or any of i ts Affiliates or Sublicensees ( i ) under this Agreement at any time following [COMPANY] ’s exercise of i ts Option pursuant to Section 2.7.2 with respect to such Collaboration Undruggable Target or ( ii ) whether or not under this Agreement, at any time prior to the expiration of the Economics Bearing Term for such Collaboratio n Undruggable Target, including any such program th at [COMPANY] or any of its Affiliates ( A ) has in - licensed or otherwise acquired from any Third Party prior to t he Effective Date or ( B ) in - licenses or otherwise acquires durin g the Economics Bearing Term for such Collaboration Undruggable Target by exercising an option right he ld by [COMPANY] or any of its Affiliates on or before the Effective Date ( each such program described in ( A ) or ( B ), a ) ; but excluding any Acquired Undruggable Target Third Party Development Program