definiens: means the amount invoiced by a Party or its Affiliate for sales of Collaboration Products to a Third'Party in the ProfitlLoss Sharing Territory, less estimates which will be adjusted to actual on a periodic basis of : ( i ) discounts, including cash discounts, discounts to managed care or similar organizations, rebates paid, credit, accrued or actually taken . including government rebates such as Medicaid chargebacks, and retroactive price reductions or allowances actually allowed or granted from the billed amount, and conunercially reasonable and customary fees paid to distributors ( other than to a distributor that is an Affiliate of such Party ), ( ii ) credits or allowances . actually granted upon claims, rejections or returns of such sales of Collaboration Products, including recalls, regardless of the Party requesting such recalls, and ( iii ) taxes, duties or other governmental charges levied on or measured by the billing amount when included in billing, as adjusted for rebates, chargebacks, and refunds