definiens: shall mean any method, procedure, service or process ( collectively, the ), discovered, developed or acquired by or on behalf of 8 SCHLESSINGER, LAX, the SCHLESSINGER LAB or the LAX LAB, whether existing on or after the ORIGINALLICENSE AGREEMENT EFFECTIVE DATE, the practice of which, in the absence of a license from YALE, wouldinfringe a VALID CLAIM of a LICENSED PATENT or which uses or is derived from LICENSED KNOW - HOW, LICENSED MATERIALS, and/or the LICENSED PATENTS, in each case that is disclosed to LICENSEE bySCHLESSINGER, LAX, the SCHLESSINGER LAB or the LAX LAB and, that, with respect to such methods that arediscovered, developed or acquired after the EFFECTIVE DATE, are discovered, developed or acquired whileSCHLESSINGER is or was MEANINGFULLY INVOLVED AT YALE and MEANINGFULLY INVOLVED AT KOLLTAN