definiens: or means in respect of any Patent Rights, any of ( i ) ceasing to maintain ( bypayment of renewal fees or otherwise ) the applicable Patent Rights ; ( ii ) withdrawing, surrendering, dedicating tothe public or allowing the applicable Patent Rights to lapse ; ( iii ) in the case of a pending applicationde - designating, or not validating or ratifying in, a country covered by the application or not entering into thenational or regional phase in a country designated in the international or convention application or(iv ) consenting to or ceasing to defend an application, action or litigation for revocation ; collectively means all Program IP, Manufacturing Know - How, UCL Background IP and theMaterials ; has the meaning in Clause 24.1 ; means all countries throughout the World ; means any and all pre - clinical and clinical test data, test designs and protocols, results and data from pre - clinical and clinical studies, information contained in or submitted in governmentlicenses and applications therefor, government certifications and findings, and related materials, data frompre - clinical and clinical experiments demonstrating or supporting bioavailability, bioequivalence, dataconcerning any adverse drug reactions ; means any [ * * * ] Field Product for the treatment of [ * * * ] and which incorporates [ * * * ] andis to be further developed in whole pursuant to the [ * * * ] ; means all uses and applications without restriction except for Exploitation of the [ * * * ] FieldProduct, including any activities of research, development or commercialisation of such [ * * * ] Field Product ; has the meaning set out in Clause 2.2.10 ; means any product or therapy within the TetCAR Field which, were it not for the licence toTetCAR Patent Rights granted hereunder, would otherwise infringe the TetCAR Patent Rights in the relevantcountry of sale ; means the program of research defined in Schedule 1 under the title TetCAR Program asconducted prior to the Amendment Date ; means excluding Manufacturing Know - How, ( i ) those patent applications listed inSchedule 2 under the title TetCAR Patents and all Patent Rights derived therefrom ( ) ; ( ii ) the Know - How described in Schedule 2 under the title TetCAR Know - How ; and ( iii ) the materials listed inSchedule 2 under the title TetCAR Materials together with all IP in the same ; CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR PORTIONS OF THIS EXHIBIT . THE COPY FILEDHEREWITH OMITS THE INFORMATION SUBJECT TO A CONFIDENTIALITY REQUEST . OMISSIONS AREDESIGNATED [ * * * ] . A COMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED SEPARATELY WITH THESECURITIES AND EXCHANGE COMMISSION