definiens: ( a ) In the case of [COMPANY] means with respect to c ompounds that are not Acylated Pyrimidines, a trace amount of Acylated Pyrimidine not intended to and unlikely to have any significant therapeutic e ffect and resulting solely from the inability of [COMPANY] or its Sublicensees, acting in a commercially reas onable manner, to produce such a compound free of Acylated Pyrimidines, the percentage of which by weight is no greater than one percent ( 1.0 % ) of the total com bined weight of Acylated Pyrimidines and Non - Acylated Pyrimidines in such combination in finishe d form ; and * CONFIDENTIAL TREATMENT REQUESTED 3 ( b ) In the case of Wellstat means, with respect to compounds that are Acylated Pyrimindines, a trace amount of Non - Acylated Pyrimidine not intended to a nd unlikely to have any significant therapeutic eff ect and resulting solely from the inability of Wellstat of its sublicensees acting in a commercially reaso nable manner, to produce such a compound free of Non - Acyl ated Pyrimindes, the percentage of which by weight is no greater than one percent ( 1.0 % ) of the total combined weight of Non - Acylated Pyrimidines and Acylated Pyrimidines in such combination in finishe d form