definiens: shall mean with respect to ( a ) calendar year 2017, zero, ( b ) calendar year 2018, $ 1,250,000, ( c ) calendar year 2019, $ 2,200,000, and ( d ) calendar year 2020 and each calendar year thereafter during the Term, $ 2,750,000 ; provided, however, 8 / 1 8 / 2 0 1 7 e x 1 0 1 l g n d a z i y o r o y a l t y a g rh t t p s : / / w w w . s e c . g o v / A r c h i v e s / e d g a r / d a t a / 8 8 6 1 6 3 / 0 0 0 0 8 8 6 1 6 3 1 7 0 0 0 0 9 1 / e x 1 0 1 l g n d a z i y o r o y a l t y a g r . h t m 1 6 / 8 78 / 1 8 / 2 0 1 7 e x 1 0 1 l g n d a z i y o r o y a l t y a g rh t t p s : / / w w w . s e c . g o v / A r c h i v e s / e d g a r / d a t a / 8 8 6 1 6 3 / 0 0 0 0 8 8 6 1 6 3 1 7 0 0 0 0 9 1 / e x 1 0 1 l g n d a z i y o r o y a l t y a g r . h t m 1 7 / 8 7 - 6 - that for the final Fiscal Year of the Term, the shall mean the applicable Minimum Annual Royalty multiplied by the fraction of such Fiscal Year that is within the Term ; provided, further, that if any Product, or any product enumerated in the definition of any Product ( or in any Schedule referenced in any such definition ), is divested as a result of a Product Change of Control or if any Product is withdrawn from the market for regulatory or safety reasons, the Minimum Annual Royalty shall be reduced by an amount that is the product of ( a ) the applicable Minimum Annual Royalty for the Fiscal Year in which such Product Change of Control or withdrawal takes place and for each Fiscal Year thereafter times ( b ) the fraction representing ( x ) the total sales of such Product or enumerated product subject to such Product Change of Control or withdrawal in the twelve ( 12 ) calendar months immediately preceding such Product Change of Control or withdrawal over ( y ) the aggregate total sales of all Products in the twelve ( 12 ) calendar months immediately preceding such Product Change of Control or withdrawal . For the avoidance of doubt, the Minimum Annual Royalty shall be adjusted according to the foregoing proviso immediately as of any Product Change of Control or withdrawal