definiens: means the costs associated with the manufacturing, purchasing, procurement and warehousing of Trospium Twice - Daily, Trospium Once - Daily and Compound, as applicable, andwith any other Processing Activities, that are actually incurred by [COMPANY] ( provided that in all cases suchamounts are not included in, and do not form the basis of, any payments payable by Esprit to [COMPANY] pursuantto Section 6.2(c ) ), including ( a ) costs associated with procuring active pharmaceutical ingredients and othermaterials used to manufacture Finished Products and/or Samples, ( b ) the cost of transportation, testing, inspections, shrinkage and scrap, related taxes ( but in all cases excluding taxes based upon income or receipts),(c ) the cost of storage, insurance and any subcontracted costs, and amounts payable to Third PartyManufacturers in connection with the manufacture and supply of Finished Products and/or Samples, includingany fees related to minimum purchase requirements, ( d ) direct labor and, to the extent not in excess of ( i ) * forTrospium Once - Daily and Trospium Twice - Daily through the Processing Assumption Date, provided theaggregate production Batches do not exceed * through the Processing Assumption Date, and ( ii ) * annuallythereafter for Trospium Twice - Daily provided aggregate annual production Batches do not exceed * ( plus, solelywith respect to this Section 1.87(d)(ii ), the increase on * and each anniversary of such date in the Producer PriceIndex, Pharmaceutical Preparations ( Series ID 325412325412 ) ( as published by the U.S. Bureau of Labor andStatistics ( http://www.bls.gov/ppi ) ) multiplied by such price ), overhead costs, including an allocation for Indevus’internal costs and expenses for supply chain management, including supply chain production planning, theformulation and placement of orders with Third Party Manufacturers, the management of inventories throughoutthe supply chain process, quality control / quality assurance, regulatory and Third Party Manufacturer oversightand cost accounting and including, with respect to Trospium Once - Daily Finished Product, and ( e ) an amountequal to the amounts payable by [COMPANY] to Madaus pursuant to Section 3.7(b)(2 ) of the Madaus License(provided that such amounts are not included in any payments payable by Esprit to [COMPANY] pursuant toSection 6.2(c ) )