definiens: Research Field " shall mean the immunization of XenoMouse Animals with Permitted Antigens, the use of materials derived or generated in whole or in part from such XenoMouse Animals that are so immunized, and the use of the XenoMouse Animals themselves, solely for the creation, identification, analysis, manufacture, research, and preclinical development of Products in the Field . For purposes of clarification, it is understood that of XenoMouse Animals with a Permitted Antigen includes the immunization of XenoMouse Animals with any formulation or construction of a Permitted Antigen, regardless of the three dimensional configuration of such Permitted Antigen, including, but not limited to, cell lines expressing such Permitted Antigen on their cell surface and chimeric molecules containing such Permitted Antigen ; provide4 .. !r0wever, that any research, development or use of Antibodies that bind to anWxcludedAntigs!(other than to determine whether they bind to a Permitted Antigen ) shall be outside of the scope of the licenses granted under the Option Agreement