definiens: means any and all Know -How that is Controlled by Editas or any of its Affiliates ( other than through the grant of a license from Juno or any of its Affiliates to Editas or any of its Affiliates ) on or after the Execution Dat e or at any time thereafter until the end of the Term, and that is ( a ) necessary or useful to research ( including Research ), develop ( including Develop ), make ( including Manufacture ), have made ( including have Manufactured ), use, offer for sale, sell, impo rt, Commercialize or otherwise exploit any Licensed RNP Complex or Licensed Product, or is otherwise related to any Licensed Program Target ; or ( b ) otherwise used by or on behalf of Editas or any of its Affiliates in the performance of the Research Progra m with respect to any Licensed Program but, in all cases ( ( a ) and ( b ) ), expressly excluding Joint Know -How, Joint Collaboration Know -How, Editas Licensed Collaboration Know -How and Excluded Know -How ; provided, however, that, on a Licensed Program -by - Licen sed Program basis, ( i ) with respect to any Know -How that is Pre Opt -In Subsequently Obtained Licensed IP for such Licensed Program, such Know -How shall be included within the definition of Editas Licensed Background Know -How only if such Know -How is includ ed in the applicable Licensed Program Addendum or ( ii ) with respect to any Know -How that is Subsequently Obtained Licensed IP, such Know -How shall be included within the definition of Editas Licensed Background Know -How only if the provisions of Section 7 . 17 are met