definiens: means : ( a ) all discoveries, information, processes, methods, protocols, formulas, data, Inventions, know - how and trade secrets, patentable or otherwise, other than Joint Information and Inventions described in Section l.l9(b)(3 ) or l.l9(c)(3 ), that ( i ) arise from the Research Program, and ( ii ) are developed or invented solely by employees of MERCK or other persons not employed by AVEO acting on behalf of MERCK ; ( b ) all discoveries, information, processes, methods, protocols, formulas, data, Inventions, know - how and trade secrets, patentable or otherwise, that arise from the Research Program and relate to a MERCK Compound ( including diagnostic uses thereof, methods of use and combination therapies comprising a MERCK Compound ), whether developed or invented ( i ) solely by employees of A YEO or other persons not employed by MERCK acting on behalf of A VEO, ( ii ) jointly by employees of MERCK and A YEO or others acting on behalf of MERCK and A YEO, or ( iii ) solely by employees of MERCK or other persons not employed by A YEO acting on behalf of MERCK ; and ( c ) any Prognostic Signature capable of predicting response ( including lack of response ) to any MERCK Compound,-any Product, or any MERCK Compound Improvement, which arise from the Research Program, whether developed or invented ( i ) solely by employees of A YEO or other persons not employed by MERCK acting on behalf of AVEO, ( ii ) jointly by employees of MERCK and AVEO or others acting on behalf of MERCK and AVEO, or ( iii ) solely by employees of MERCK or other persons not employed by A YEO acting on behalf of MERCK