definiens: shall mean an individual 's response ( efficacy or adverse drug reaction ) to any Statin in the Statin class ( Crestor, Lipitor, Pravachol and Zocor ), which shall include a response to each of the four statins ( Crestor, Lipitor, Pravachol and Zocor ), wherein the p - value for the correlation to at least three of the statins is not more than 0.05 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan AND the p­value for the correlation to the fourth statin is not more than 0.1 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan . A correlation to a class - wide effect shall NOT include a response to each of the four statins ( Crestor, Lipitor, Pravachol and Zocor ), wherein the p - value for the correlation to at least three of the statins is more than 0.05 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan AND the p - value for the correlation to the fourth statin is more than 0.1 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan, NEITHER shall a correlation to a class - wide effect include a response to each of the four statins ( Crestor, Lipitor, Pravachol and Zocor ), wherein the p - value for the correlation to at least three of the statins is more than 0.05 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan OR the p - value for the correlation to the fourth statin is more than 0.1 with correction for multiple testing as defined by [COMPANY] in the Research Study Plan