definiens: shall mean efforts reasonably consistent with those efforts used by API with regard to its developmental work and commercial activities for its own products deemed to have similar commercial potential, consistent with its business, research and development practices, and applicable legal and regulatory requirements . For API to have been deemed by DOW to have used their commercially reasonable efforts, DOW expects that in the TERRITORY API should : 4.1.1 Provide DOW with significant development information for the commercialization of at least one PRODUCT within eighteen ( 18 ) months from the EFFECTIVE DATE ; -13 - 4.1.2 . Provide a marketing plan to DOW for the selected PRODUCT within three ( 3 ) years from the EFFECTIVE DATE ; 4.1.3 Assume all liability ( indemnification ) for any Clinical Trials on PRODUCT in the TERRITORY which are done under API 's direction after the EFFECTIVE DATE and begin clinical trials on at least one PRODUCT within three ( 3 ) years from the EFFECTIVE DATE ; 4.1.4 File an NDA with a REGULATORY AUTHORITY as promptly as possible, no later than one ( 1 ) year after completion of the clinical trials relating to such NDA ; 4.1.5 Begin marketing PRODUCT within six ( 6 ) months after APPROVAL ; and 4.1.6 Expand the number of countries for marketing the APPROVED PRODUCT by marketing in at least one additional country within one year after the first sales occur under Article 4.1.5