definiens: shall mean, with respect to a particular BGM Commercialized Diagnostic Product, the actual gross amount invoiced by BGM or its Affiliates for commercial sales of such product after deducting, in accordance with GAAP, the following : ( i ) trade, cash and quantity discounts reasonably consistent with industry standards ; ( ii ) credits or allowances for damaged or spoiled product, returns, recalls or rejections of products, including allowance for breakage or spoilage ; ( iii ) sales, value added, excise or other direct taxes, and freight, postage, shipping and transportation insurance charges and additional transportation, custom duties, and other governmental charges on the BGM Commercialized Diagnostic Product ; and ( iv ) chargebacks, rebates or similar payments or credits directly related to the BGM Commercialized Diagnostic Product consistent with reasonable industry standards granted to managed health care organizations, wholesalers, distributors, buying groups, retailers, Health Benefits Population, or other institutions or health care organizations or to federal, state / provincial, local and other governments, their agencies and purchasers and reimbursers