definiens: means all Infonnation and Materials Controlled by [COMPANY] prior to or during the Term necessary or useful for the Development or Commercialization of Licensed Product, including but not limited to the following infonnation : ( 1 ) information disclosed in the IND for Alfimeprase as of the Effective Date ; ( 2 ) information disclosed as of the Effective Date in any IND supplements for Alfimeprase ; ( 3 ) all [COMPANY] - sponsored collaborator data and results ( subject to any contractual confidentiality obligations of [COMPANY] to Third Parties regarding such results ) ; ( 4 ) any regulatory data which [COMPANY] provides to [COMPANY] ; and ( 5 ) such infonnation which [COMPANY] expressly designates in writing it intends to include as [COMPANY] Know­How under this Agreement . [COMPANY] Know - How does not include [COMPANY] Material and Manufacturing Information .