definiens: means, with respect to a particular itei77 and a particular Patent, that suchPatent claims or covers _ in aiiy of the countries of manufacture . use . and/or sale . ( a ~ thzcc~~n ~ ositi ~ n ~~1 ` such item . and of its in~~rzdiz ~ Its or formulations or ~in~ t ~ c ~ o ~ luc : i colltaini ~ l~~ or that- - _ — ~ — is made us ny.~such item _ virtue of such_~ociuct ce ~ ntaininy . T or be n~~ made usin<7 such item;(b_a methocl ol ~ mai . n:~_or usin~.~an~ _ of the tore~~c~ nz ~ thin~_i - efzrrecj tq in ( ~ _ _ andior ~cj an _ item .. _ _ used or~~rescnt in thy_manufacture cat an_~ ' ofth~ f~~t~,~~ n<~thin ~ r ~ ferre~_te~ in ( ~~Z(far- e ~ al~ e_~~~it11 tes ~ e_ct to a, biolo~;ic, _ anti ~~ector,~l ~ isiili~3 or cell line used to niatzufac : tut ~ e such ~ roduct c ~ i~-.—item or anv in<~rediznt_in either of them )