definiens: shall mean A&P Spend and PDE Value with a combine d value of at least ( x ) [ * * * ] percent ( [ * * * ] % ) of the Net Sales in cale ndar year 2005, ( y ) [ * * * ] percent ( [ * * * ] % ) of the N et Sales in calendar year 2006, and ( z ) [ * * * ] percent ( [ * * * ] % ) of the Net Sales in calendar years after December 31, 2006 and thereafter ; provided however that ( i ) if any amendment to any agreement between [COMPANY] ( or any of its Affiliates ) and Merck & Co., Inc. ( or any of its Affiliates ) lowers such minimums, then such minimums shall automatical ly and immediately be reduced hereunder to equal such reduced amount and, ( ii ) if any such agr eement containing such minimums is terminated or otherwise no longer in force, or any such agreement remains in force but the minimums are no longer in force or no longer apply for any reason, then such minimums shall automatically and immediately be reduced hereunder to zero