definiens: means all Know - How and Materials comprising or relating to any resultsgenerated solely by or on behalf of AMT in its Exploitation of GDNF Products up to the date of any termination of thisAgreement comprising ( i ) construction of the baculoviruses required for manufacturing of a GDNF Product in insect cells andany other process development or optimization of AMT ’s baculovirus - based vector production system in insect suspensionculture ( upstream ) or affinity chromatography - based purification system ( downstream ) ; or ( ii ) improvements andcharacterization of AMT ’s AAV5 platform, particularly for CNS applications ; in each case including but not limited to allimprovements, modifications and developments generated solely by or on behalf of AMT in its Exploitation of GDNFProducts up to the date of any termination of this Agreement to the AMT Licensed Know - How ( including AMTManufacturing Technology ) and Materials comprising AMT Licensed Know - How as of the Original Agreement Effective Daterelating to the subject matter described in clauses ( i ) and ( ii ) above