definiens: GW Product(s)Hwnan Therapeutic(s ) ", which shall include all therapeutic modalities, including but not limited to small molecules, vaccines, aptarners, antisense, oligonucleotides, gene therapies and monoclonal antibodies that are discovered, developed and/or optimized using : 2 L _ _ _ _ -'- _ _ _ _ _ · _ _ _ _ . -CONFIDENTIAL ~EA - rNENr ( i ) J'Target(s ) ", which shall mean a gene, including its regulatory region and direct transcription or translation products, which is I ) identified as a site for therapeutic intervention for a Human Therapeutic, as defined above ; and 2 ) differentially expressed in one or more Pharmacogenomics Projects ; andlor ( ii ), which shall mean a defined collection of genes that I ) when used individually or collectively provide a measure of a treatment 's or a compound 's effect on the biology of a sample ; and 2 ) is obtained during the j course of the Pharmacogenomics Program . J Notwithstanding any provision in this Section, Human Therapeutics shall not include Protein Therapeutic Products