definiens: as defined in the Supply Agreement, means, the difference, if any, between ( i ) thepurchase price per gram of API [ * * * ] following expiration of the [ * * * ] notice period of a Refusal to Supply by [COMPANY], minus ( ii ) [ * * * ] amount equal to [ * * * ] Dollars ( U.S. $ [ * * * ] ), subject to annual adjustment for inflation, from the EffectiveDate to the date of purchase by MEDINOL, using the United States Bureau of Labor Statistics Producer Price Indexfor Pharmaceutical Preparation Manufacturing published at www.bls.gov . To calculate the Excess API Cost, allpayments made by MEDINOL for API in foreign currency shall be converted into United States Dollars at theconversion rate existing in the United States ( as reported in The Wall Street Journal, Eastern Edition, for purchasingUnited States Dollars ) on the last business day of the applicable calendar quarter in which the purchase of API tookplace