definiens: means ( a ) any amino acid ( including any natural, synthetic, modified or other amino acidanalogue ) chain that is a human or animal protein including, without limitation, any protein or polypeptide listed onSchedule 2.1(b)(1 ) attached hereto, or any variant, homolog, derivative, mutant or fragment of the foregoing subsection ( a),including, without limitation, amino acid chains resulting from the use of Shuffling, in each case other than any ( i ) CTLA-4Variant or ( ii ) Excluded Protein Variant or Vaccine, ( each such protein or variant, homolog, derivative, mutant or fragmentthereof, an ) and ( b ) any Other Protein Molecule that is conjugated or otherwise coupled to anyother molecule ( e.g., polyethylene glycol, immunoglobulin domain, sialylation, pegylated, or glycosylation )