definiens: means ( a ) licenses granted by [COMPANY] or its Affiliatesunder the [COMPANY] Core Technology Patents, the [COMPANY] Manufacturing and Analytical Patents, orthe [COMPANY] Manufacturing and Analytical Know - How ( but not under the [COMPANY] Product - SpecificPatents or the [COMPANY] Product - Specific Know - How ) to enable such Third Party to manufacture orformulate oligonucleotides, where ( i ) such Third Party is primarily engaged in providing contractmanufacturing or services and is not engaged in drug discovery, development orcommercialization of therapeutics in any material respect ; and ( ii ) [COMPANY] and its Affiliates do notassist such Third Party to identify, discover or make an antisense oligonucleotide designed tobind to ANGPTL3 ; and ( b ) material transfer, collaboration, or sponsored research agreementswith academic collaborators or non - profit institutions solely to conduct non - commercial research