definiens: shall mean any Invention that relates to : ( a ) thecomposition of matter of the [COMPANY] Compound ( and not the Five Prime Compound ) ; ( b ) method ofmanufacture or formulation of the [COMPANY] Compound ( and not the Five Prime Compound ) as asingle agent ; ( c ) a method of use of the [COMPANY] Compound ( and not the Five Prime Compound ) asa monotherapy or as used with agents, antibodies or compounds other than an Inventioncomprising, whether generically or specifically, the use of both the [COMPANY] Compound ( and/or anyother antibodies that are designed to selectively bind to PD-1 ) and a Five Prime Compound(and / or any other antibodies that are designed to selectively bind to CSF1R ) ) ; or ( d ) arising fromthe development of the Dako Assay