definiens: means use as a human topical microbicide, alone or in combination withother compounds, for application to the skin, mucosal and/or epithelial tissue as an active ingredient informulations such as creams, foams, jellies, or other similar formulations, including contraceptive and other vaginaldelivery devices such as sponges, intrauterine devices, diaphragms and condoms ; but Permitted Field of Use doesnot include, and specifically excludes : ( a ) non - human uses ; ( b ) human application for both systemic therapeutic uses and systemic post - exposureprophylactic uses ; and ( c ) uses when applied to or incorporated into any surface ( except for human surfacesconsisting of skin, mucosal and/or epithelial tissue ) or device ( except contraceptive and other vaginal deliverydevices as provided for above in this definition ) including, but not limited to, gloves, aprons, tubing and filters