definiens: means total, worldwide Net Sales aggregated during any given calendar year ( or portion thereof with respect to the calendar year in w hich the Effective Date occurs, and with respect to the calendar year during which this Agreement terminates or expires ): Percentage of Annual Net Sales Annual Net Sales [ * * * ] % < $ [ * * * ] million [ * * * ] % Portion of Annual Net Sales equal to or greater than $ [ * * * ] million but less than $ [ * * * ] million [ * * * ] % Portion of Annual Net Sales equal to or greater than $ [ * * * ] million but less than $ [ * * * ] million [ * * * ] % Portion of Annual Net Sales equal to or greater than $ [ * * * ] million but less than $ [ * * * ] million [ * * * ] % Portion of Annual Net Sales that is $ [ * * * ] million or greater Royalties shall be paid under this Section 4.3.1, on a country -by - country and Licensed Product -by - Licensed Product basis, on Net Sales of each Licensed Product made from the Fi rst Commercial Sale of such Licensed Product in each country during the Royalty Term applicable to such Licensed Product