definiens: means, with respect to a particular time period, the total amounts received or invoiced by TGTX and itsAffiliates and Subcontractors for sales of Finished Product made during such time period to unaffiliated Third Parties, lessthe following deductions to the extent actually allowed or incurred with respect to such sales : ( a)discounts, including cash, trade, and quantity discounts, retroactive price reductions, charge - backpayments, and rebates actually granted or administrative fees actually paid to trade customers, patients(including those in the form of a coupon or voucher ), managed health care organizations, pharmaceutical benefit managers, group purchasing organizations, federal, state, or local governmentand the agencies, purchasers and reimbursers of managed health organizations, pharmaceutical benefitmanagers, group purchasing organizations, or federal, state or local government ; ; ( b)credits or allowances actually granted upon prompt payment or losses actually incurred as a result ofdamaged goods, rejections or returns of such Product, including in connection with recalls, and all otherreasonable and customary allowances and adjustments actually credited to customers