definiens: means any and all Know - How that is Invented by either or both Parties, their Affiliates, or its ortheir licensees, sublicensees or subcontractors ( whether solely, jointly or otherwise ), as applicable, in the performance of their respectiveDesignated Activities under this Agreement, but excluding any and all ( a ) [COMPANY] Collaboration Know - How, ( b ) [COMPANY] ContributedKnow - How, ( c ) Know - How that is Invented by [COMPANY], its Affiliates, or its or their licensees, sublicensees or subcontractors that constitutesdevelopments, enhancements, modifications or other improvements to, or progeny, mutants, fragments, or derivatives of, or other discoveriesor inventions directly related to Know - How that is Controlled by [COMPANY] or one of its Affiliates and used by or on behalf of [COMPANY] orone of its Affiliates in the performance of [COMPANY] Designated Activities ( which shall be considered [COMPANY] Collaboration Know - How),and ( d ) Novel Viral Vector Collaboration Know - How