definiens: means solid - phase or solid supported organic chemistry andrelated Combinatorial Technology based techniques for drug discovery and optimization inpreclinical research and development, for use in the research and development . of pharmaceuticalsfor human use or research and development of other products ( e.g. agricultural products ), andincluding but not limited to the following, all as applied to Combinat.orial Technology : ( i ) pins and / orresins, particularly the optimization of solid phases, grafted surfaces and linkers, i.e :, extending fromt.he inert substrate to and iIicluding the reactive moiety of the Iinker(s ) ; ( Ii ) methods and proceduresfor use thereof, i.e., for performing solid - phase organic chemistry thereon, including conditions forperforming organic reactions generally and/or certain types or classes of organic reactionsspecifically ( e.g., solvent(s ), temperature, catalyst(s ) and the like ) ; ( iii ) fonnats, e.g., mu1tipinsystems or other spatially addressable arrays, including automation software therefor, and roboticstechnology for compound synthesis, including automation software therefi r ; ( Iv ) analytics tomonitor the preceding ; ( v ) computational chemistry, including molecular modeling, diversitymodeling and data handling techniques for creating and maintaining data bases, and informatics ; ( vi)assay methods, including robotics technology ( with automation software therefor ) and affinityselection - mass spectrometry ; and ( vii ) in vitro and in vivo test systems for assessment of safety, f:\wpgen\c;\l, m\ciba\combdlem.2111114195 - 7 - efficacy and pharmacokinetics ( mcluding ADME characteristics ) . Notwithstanding the foregoing, the Teclmology Transfer Fiel.d specifically excludes ( a ) peptides and biological molecules ; ( b ) allexisting and future [COMPANY] Combinatorial Libraries and comPounds contained tha - ein ; ( c ) ChironInformation relating to ; or [COMPANY] participation in, the application of any of the fcJregoing techniquesto the design, synthesis and/or characterization of specific compOlmd sets or h1Jraries or individualcompounds or materials, or the use or application thcceof ; ( d ) medicinal chl : iJ!istry ; ( e ) specificassays and/or targets ; and ( f ) all biological and chemical results and data, including existing andfuture [COMPANY] databases .