definiens: means the carrying out of obligations or tasks by a Party in a sustained and diligentmanner using good faith efforts and resources commonly used in the pharmaceutical industry for a similar product ( oractivities designed to identify such product ) of similar commercial potential at a similar stage in its lifecycle, taking intoconsideration its safety and efficacy, its cost to develop, the competitiveness of alternative products, its proprietary position, the likelihood of Regulatory Approval, its profitability and all other relevant factors, which efforts shall be consistent with theexercise of prudent scientific and business judgment applied in the pharmaceutical industry by a party of similar size toproducts or research, development, regulatory approval and marketing projects of similar scientific and commercial potential . Without limiting the generality of the foregoing, Commercially Reasonable Efforts requires that : ( i ) aParty promptly assign responsibility for such obligations to specific employee(s ) or consultant(s ) who are held accountable forprogress and monitor such progress on an ongoing basis, ( ii ) such Party set and consistently seek to achieve specific andmeaningful objectives for carrying out such obligations and ( iii ) such Party consistently makes and implements decisions andallocates resources designed to advance progress with respect to such objectives