definiens: means, with respect to the efforts to be expended by a Party with respect to any objective, those reasonable, good faith efforts to accomplish such objective as such Party would normally use to accomplish a similar objective undersimilar circumstances . With respect to any efforts relating to the Development, Regulatory Approval or Commercialization of a Candidate orProduct by a Party, generally or with respect to any particular country in the Territory, a Party will be deemed to have exercisedCommercially Reasonable Efforts if such Party has exercised those efforts normally used by such Party, in the relevant country, withrespect to a compound or protein, product or product candidate, as applicable ( a ) of similar modality Controlled by such Party, ( b ) to whichsuch Party has similar rights, ( c ) which is of similar market potential in such country, and ( d ) which is at a similar stage in its development orproduct life cycle, as any Candidate or Product, in each case, taking into account all Relevant Factors in effect at the time such efforts areto be expended . Further, to the extent that the performance of a Party ’s obligations hereunder is adversely affected by the other Party’sfailure to perform its obligations hereunder, the impact of such performance failure will be taken into account in determining whether suchParty has used its Commercially Reasonable Efforts to perform any such affected obligations