definiens: shall mean any method : K1=!:}theuse()rpracticeo [ w4ichw;oPcldcOIlStitu te ; ~utforthe liyeIU?egran ~ edhel'ein~ an . infringe1Uentof < myI ~ ved Valid * ClaimofrRNApateIlts,'and(b)~hicR'#titi ~ e.~.th ~ TI.1A"I\tf¢tho < i(as(f ~ fined intheTMA,.tipense ' · · Agreement ), ( and;(c ) whichisusedtodetenwn~;thepresence.ot'anioUnfofrib'osomal nucleic, aCid derived . from an organismormembers'of'agroup oforganisrris ] 412741 vl / SD 8%HIOl!.DOC 3 . * Confidential Treatment Requested Confidential 1.16 . shall mea~ any product : Ea ) ~e man ~ facture, use, sale or lqiportatiQnof which would, but for the hcense granted nerem, constitute an ' * infringement of olle qr .mQie ' Issued Valid Claims of the rRNAPatents, and ( b ) which utilizes the TIV.(:A Method ( asdefui ~ dln the TMA License Agreement ), and ( G ) wbichis used to determine thepresence~. or amount of ribosomal nucleic acid derived from an organism or members of a group oforganism~