definiens: means ( a ) with respect to any Co - Commercialized Program for which Celgeneexercises the [COMPANY] Program Option at IND Acceptance, [ * * * * ] ; ( b ) with respect to any Co - Commercialized Programfor which [COMPANY] exercises the [COMPANY] Program Option at Completion of Phase I MAD, [ * * * * ] ; ( c ) with respect toany Co - Commercialized Program for which [COMPANY] exercises the [COMPANY] Program Option early under Section 3.6(c ), [ * * * * ] ; ( d ) with respect to a Buy - In Program, [ * * * * ] ; ( e ) with respect to any Picked Validated Program selected byCelgene, [ * * * * ] ; and ( f ) with respect to any Split Program, [ * * * * ] - 1 -2 . Amendment of Section 2.4(a )