definiens: means, as of the First Amendment Effective Date, the Santaris Agreement, UNC Agreement, UT Southwestern Agreement s and the [ * ] Agreement . Upon the selection of a Replacement Target, the Parties shall amend this definition as necessary to add all additional licen se agreements between Miragen and a Third Party entere d into before the Effective Date pursuant to which Miragen has a sublicensable license to Miragen Ther apeutic IP that covers such Replacement Target or Licensed Oligos that directly and selectively modul ate such Third Target . Upon the selection of a Replacement Target, the Parties shall amend this de finition to remove all license agreements between Miragen and a Third Party pursuant to which Miragen has a sublicensable license to intellectual proper ty that is no longer Miragen Therapeutic IP because it covers a member of the microRNA target family that was replaced by such Replacement Target or Licensed Oligos that directly and selectively modulate such member . ” 8