definiens: means the use of a Licensed Product ora Compound in develC?Prnent as a Licensed Product in a cancer patient who [ was,:,tieitt ~ ci witfl·~~label ~ ind·icat ~ d.dose"of a Taxane ] and either [ failed, to~ respond ] or [ initi.lly r,:~pprid ~ d ] but [ Iater.cc)'ritinued ] to [ show tumor progression ' . ] 1.50 means the use of a Licensed Product or a Compound in development as a Licensed Product, in a cancer patient who [ Wa . S ~ ij'Vf # · bi(Qie~'triated ] with a rt ~ ane, ] where [ Taxarles ] are [ n9 ~ R~'glst, i ~ icl ] in the [ ~9~·Otly : fof.tre ~ tment ] for [ suc~ cancer treatmenf, ] e.g. ( but without limitation ) [ me ~ as ~ a~~c : colorec~1 cancer . ] 1.51 means the use of Licens ~ d Product or a Compound in development as a Licensed Product in a cancer patient [, eifher . alonej or [ in combination ] with [ another anti - cancer'drug, ] wher~, [ TaX, ne~ areJ ~ bel·.indicated for use ] as [ part ] of [ routine first U ~ e chemotberapY. ] 1.52 means the entire world, subject to Section 13.8(a )