definiens: means ( i ) Master Donor Strains, Master Virus Seeds and Working Seeds ; ( ii ) all Technical Information relating to Master Donor Strains, the Master Virus Seeds and the Manufacture of the Intermediate Product ; ( iii ) all information relating to the Discloser 's business ; and ( iv ) all information arising pursuant to this Restated Agreement, the 1995 Development Agreement and the 1997 Contract Manufacture Agreement between the parties, disclosed by one party to this Restated Agreement ( the ) to the other ( the ) in connection with this Restated Agreement, excluding any such information which : 2.45.1 is or was already known to the Recipient at the time of disclosure by the Discloser as evidenced by the written records of the Recipient ; or 2.45.2 was at the time of such disclosure or communication by the Discloser or thereafter becomes or became published, accessible to the public or otherwise in the public domain other than through any act or omission of the Recipient ; or 2.45.3 must be disclosed to government inspectors in the discharge of statutory obligations provided that before disclosure the Recipient shall use reasonable endeavors as it would in respect of its own Restricted Information to obtain from such government inspectors any assurances as regards confidentiality as may be afforded to such information in the circumstances ; or 2.45.4 must be disclosed by the Recipient to the relevant Agency in the course of applying for, obtaining or maintaining regulatory approval ; or 2.45.5 is hereafter disclosed to the Recipient by a third party, who to the knowledge of the Recipient does not have any obligations of confidentiality to any third party or who has not, to the actual knowledge of the Recipient, derived it directly or indirectly from the Discloser or the University of Michigan ; or 2.45.6 is required to be disclosed by law