definiens: mean s any unified dose ( e.g., not a kit of two separate and d istinct drug dosage forms ) of pharmaceutical produc t which is comprised of Product and other therapeutically acti ve compound(s ) and/or ingredient(s ) ( collectively t he ), Net Sales of Product, for the purposes of determining royalty payments, shall be determine d by multiplying the Net Sales of the Combination Produc t by the fraction, A / ( A+B ) where A is the weighte d average sale price of the Product when sold separat ely in finished form, and B is the weighted average sale price of the Other Products sold separately in finished f orm, in each case in the country of sale of the Com bination Product in the calendar quarter of such sale, provi ded that the Net Sales in any royalty period shall in no event be reduced by more than fifty percent ( 50 % ) by reason of the foregoing sentence . In the event that no sep arate sales are made of either the Product or the Other Product s, the reasonably estimated commercial value thereo f will be used instead of the sale price . Notwithstanding the foregoing, the adjustment of Net Sales as set fort h in this paragraph shall not apply if the composition of mat ter of such other active ingredient is not claimed in any issued and unexpired patent claim owned by CRXX or a third party