definiens: means all inventions, discoveries, know - how, meUlodologies, teclUlOlogy, tangible malerials ( includi.ug nucleic acids, peptides, vectors, proteins, and tlteJike ) Utal ( a ) pertain to Recombinant Factor XW, ( b ) were invented, discovered, developcxl or otherwise generated by or for WEN, o.nd ( c ) arc owued and Controlled by WEN as of the EffecLive Date . For the avoidance of doubt . Licensed Know­How sball not include such items whicb : ( i ) at the lime of disclosure is in the public domain ; ( ii ) prior to the disclosUIe from WEN to NN, was in NN 's possession ; or ( ui ) are developed independently by NN without nny use of any confidential ZGHN know - how or confidential WEN patent rights whatsoever . The TechnoLogy Transfer Letter lists the information and tangible biological materials, reagents, assays and otber items to be transferred to NN pursuant to Article 5 Ulat contain Licensed Know - Ilow