definiens: means : ( a ) with respect to the eﬀorts to be expended by a Party withrespect to any objective other than Developing, Manufacturing, Commercializing or otherwise Exploiting a Product, suchreasonable, diligent, and good faith eﬀorts as such Party would normally use to accomplish a similar objective under similarcircumstances ; and ( b ) with respect to any objective relating to Developing, Manufacturing, Commercializing or otherwiseExploiting a Product by a Party, that level of eﬀorts and resources that such Party would normally devote to the performanceof such activities for a product owned by it, which is of a similar commercial potential at a similar stage in its lifecycle, in eachcase taking into account issues of safety and eﬃcacy, product proﬁle, the proprietary position, the then - current competitiveenvironment for such product and the likely timing of such product ’s entry into the market, the pricing and launching strategyfor such product, the regulatory environment and status of such product, and any other relevant factors, including otherscientific,2Exhibit 10.1CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [ * * * ], HAS BEEN OMITTEDBECAUSE IT IS NOT MATERIAL AND WOULD LIKELY CAUSE COMPETITIVE HARM TO MERSANA THERAPEUTICS, INC . IFPUBLICLY DISCLOSEDtechnical and commercial factors . For clarity, Commercially Reasonable Eﬀorts will not mean that a Party guarantees that itwill actually accomplish the applicable task or objective