definiens: means any decision with respect to the following is sues : ( a ) subject to Section 3.5.1(b ), thereplacement of any Program Target with another Targ et ; ( b ) the nomination of an IL-23 Aptamer or a Col laborationCompound as a Lead Compound ; ( c ) the nomination of a Lead Compound as a Clinical Candidate ; ( d ) the [ * * * ] of [ * * * ] to be [ * * * ] in [ * * * ] to the [ * * * ] ; ( e ) the use or applica tion by ELAN of [ * * * ] and/or [ * * * ] and [ * * * ] in the conduct of the ResearchProgram and/or the Development of Clinical Candidat es ; and ( f ) whether ELAN should [ * * * ] obtain a lice nse to a BlockingThird Party Patent or any other Third Party Patent Rights