definiens: means the TNF - a : murine al}tibody designated nmAb32 " by Peptide Technology Limited, as deposited in ' PHLS Centre for Applied Microbiology and ~esearch ECACC No . 89090302 ), and murine and human antibodies with properties as described for mAb32 in the published patent application PCTjAU90j00037 which enhance or do not inhibit TNF­a : mediated tumor regression in the in vivo assay described in BritJ.Cancer ( 1992 ) 63:832 - 836 but which do not inhibit the killing by TNF - a of WEHI tumor cells in the in vitro WEHI-164 cytotoxicity assay described in Brit . J.Cancer ( 1992 ) 63:832 - 836 or of human tumor cells in corresponding assay svstems