definiens: means the Targets listed on Schedule 1, as amended from time to time in accordance withSection 3.5 ; provided, however, that there shall be no more than four ( 4 ) Targets listed on Schedule 1 at any point in time, andeach of these shall be a Target that ELAN reasonabl y believes based on publicly available literature o r proprietary data hasactivity in the Target Selection Field . For purpose s of clarity, the term Program Target shall include as the Target againstwhich the SELEX ™ Process may be performed ( a ) in th e case of a ligand, ( i ) the designated ligand and t he designatedcomponents or subunits [ * * * ] and ( ii ) [ * * * ] to whic h [ * * * ] and the [ * * * ] or [ * * * ] of such [ * * * ] but [ * * * ] any other [ * * * ] orother [ * * * ] that [ * * * ] with such [ * * * ] or [ * * * ] or such [ * * * ] or [ * * * ] ; ( b ) [ * * * ] of a [ * * * ], ( i ) the [ * * * ] and the [ * * * ] or [ * * * ] of such [ * * * ], and ( ii ) a [ * * * ] to which [ * * * ] and the [ * * * ] or [ * * * ] of such [ * * * ] but [ * * * ] anyCONFIDENTIALPortions of this Exhibit were omitted and have been filed separately with the Secretary of the Commiss ion pursuant to theCompany ’s application requesting confidential treat ment under Rule 406 of the Securities Act