definiens: means, as to a CompanionDiagnostic Assay that qualitatively or quantitatively measures neutralizing antibodies toany AAV capsid contained in a Licensed Product or can be used to otherwise assesswhether a clinical trial subject or a patient is a candidate for treatment with a LicensedProduct, any modification made by [COMPANY] or its Affiliates, or on any of their behalf by aThird Party contractor, to ( a ) any materials provided by Spark to [COMPANY] ( or to an Affiliate orThird Party contractor designated by [COMPANY] ) under the License Agreement that areincorporated into or otherwise used as part of such Companion Diagnostic Assay, or ( b)Spark ’s proprietary methods disclosed to [COMPANY] ( or to an Affiliate or Third Party contractordesignated by Pfizer),1CONFIDENTIALEXECUTION VERSIONNovember 6, 2017which methods are incorporated into or otherwise used to perform such CompanionDiagnostic Assay