definiens: means:(a ) with respect to a Non - MAP Collaboration Target that is not an Additional Biological Target or an Additional DualTarget, a chemical entity, other than a Biological, which is intended to and actually inhibits or modulates the activity ofsuch Target;(b ) with respect to a Non - MAP Collaboration Target that is an Additional Biological Target and that the Parties expresslyagree in writing pursuant to Section 3.7.1 to designate as a Potential Collaboration Target, a Biological which is intendedto and actually inhibits or modulates the activity of such Target ; or -3-(c ) with respect to a Non - MAP Collaboration Target that is an Additional Dual Target, ( i ) a chemical entity, other than aBiological, which is intended to and actually inhibits or modulates the activity of such Target and ( ii ) subject to theexpress prior written agreement of the Parties pursuant to Section 3.7.3, a Biological which is intended to and actuallyinhibits or modulates the activity of such Target