definiens: shall mean any enzyme that ( A ) has the ability to recognize the structure fom1ed by the hybridization of an Invader Probe and a Primary Probe to their cognate Target sequence such that the Invader Probe overlaps, at its 3 ' terminus by at least one nucleotide, the duplex fonned by the hybridization of the Primary Probe to the complementary region of the Target ; ( B ) has the ability to cleave tlie Non - Hybridizing Region from the Primm Probe when suoh structill'e exists ; and ( C ) h, as limited or no nucleic acid s thesis abili ~. It is acknowledged and agreed that Cleavase Enzyme shall include the enzymes having the three properties described in ( A ), ( B ), and ( C ) of this Section 1.8 above, regardless of whether or not the enzyme has other properties or uses, including ausing dea~ ' age under different circumstanoes, or cleaves additional nucleic aci bases alon with, the N0n-1'1)1bridizing Region . Cleavase Enzyme shall include those enzymes identified on Exhibit 1.8, as may be updated from time to time by TWT