definiens: ~hall ~1n Critical TherapeuticCI1 Improvements " shall mean any and all improvement > to the CIl Patents, the CTI Know - How, or the CIT Monoclonal AntibOOy that have been conceived, 2 J, n ..., . I. 2 < fll January ~,2(X)S efealcd . developed anUtor otherwl$C invenlcd by or 00 behalr or en and/or Bel duriog tbolc Term . for Ihe me of clarily, il is understood Ihal UCI improvemen ls included within Ibis ddinilion .'>hall be smelly limited toiJllpro, · elncnl.~ in a kit or assemblage of Ieagents for IfIelI ~ Ufjng only HMGB - l in humans or lInimal~, and any Bel improvement that has application 10 a kil or a!I.'l.embla~ of t"Ca#nb for the measurement of ally OIOOr anaiyte is not within the scope or th!.~ definition