definiens: means, with respect to an Operating Party and its Affiliates, a specificproduct within the Core Business of such Operating Party and its Affiliates as set forth on Exhibit D as the same shallbe amended in accordance with the following . Each Operating Party shall notify the other Parties annually of anychange in the Core Business Products of such Operating Party and its Affiliates, together with adequate supportingdocumentation, and, absent a dispute, Exhibit D shall be amended to reflect such change subject to the followingconditions : ( i ) neither Operating Party shall be required to delete any product which is * * * * * * * * * * * * ; ( ii ) any * * * * * * * * * * * * product * * * * * * * * * * * * may be added to or deleted from Exhibit D by either Operating Party without restriction providedthat in the case of an addition such product is under development or being commercialized by such Operating Party orits Affiliates ; ( iii ) an Operating Party may add a * * * * * * * * * * * * product to Exhibit D only if such product meets any one ofthe following criteria : ( A ) For products in the stage of research or development, ( 1 ) such Operating Party and itsAffiliates have spent in the preceding year at least * * * * * * * * * * * * for research and/or development of such product, or(2 ) such Operating Party or its Affiliates have developed a 6Confidential material omitted and filed separatelywith the Securities and Exchange Commission