definiens: means all patents and patent applications that ( a ) are Controlled as of the Effective Date or during the Term by PGx and that claim the compos ition of matter, manufacture or use in the Field of the Compound, ( b ) are substitutions, divisions, continu ations, continuations - in - part ( to the extent direct ed to the subject matter disclosed in a patent or patent appl ication described in ( a ) ) and requests for continue d examination of any of the foregoing, ( c ) are patents arising fr om or claiming priority to any of the foregoing, ( d ) are reissues, renewals, registrations, confirmations, re - examinat ions, extensions, and supplementary protection cert ificates of any of the foregoing, and/or ( e ) are foreign equiva lents of any of the foregoing . For the avoidance of doubt, the PGx Patents shall include any patent or application claiming a Sole Invention of PGx and any Joint Pat ents, in each case solely to the extent that such patent or patent application claims the composition of matter, manufacture, or use in the Field of the Compound