definiens: shall mean all Know - How now or in the futureControlled by [COMPANY], that relates to RNAi technology, products or processes, including, ( a ) the general structure, architecture, or design of nucleic acidbased molecules which engage RNAi mechanisms in a cell ; ( b ) chemicalmodifications of nucleic acids ( including any modification to the base, sugar orinternucleoside linkage, nucleotide mimetics, and any end modifications ) whichdo not abolish the RNAi activity of the nucleic acid molecules in ( a ) ; ( c)manufacturing techniques for the nucleic acid based molecules or chemicalmodifications of ( a ) and ( b ) ; and ( d ) all uses or applications of nucleic acidbased molecules or chemical modifications in ( a ) or ( b ) ; but excluding Know - Howwhich relates solely to ( i ) a specific Target or small group of Targets ; or ( ii)delivery technologies which may be broadly employed for delivery of nucleic acidbased molecules