definiens: means all patents and patent applications that ( a ) are Controlled as of the Effective Date or during the Term by CRXX or its Affiliates a nd that claim, and only to the extent that such pat ents and patent applications claim, the composition of matte r, manufacture, or use of the Compound, such patent s and patent applications and the applicable claims there of set forth on Exhibit C ( including any future cla ims derived therefrom ), ( b ) are substitutions, divisions, conti nuations, continuations - in - part ( to the extent dire cted to the subject matter disclosed in a patent or patent appl ication described in ( a ) ) and requests for continue d examination of any of the foregoing, ( c ) are patents arising fr om or claiming priority to any of the foregoing, ( d ) are reissues, renewals, registrations, confirmations, re - examinat ions, extensions, and supplementary protection cert ificates of any of the foregoing, and/or ( e ) all foreign equiva lents of any of the foregoing . For the avoidance of doubt, the CRXX Patents shall include any patent or applicatio n claiming a Sole Invention of CRXX and any Joint P atent, in each case solely to the extent that such patent or patent application claims the composition of mat ter, 779758 v7 / HN 3 manufacture, or use of the Compound ( whether or not such patents or patent applications are listed on Exhibit C )