definiens: shall mean a certain chemical substance having the chemical structure of 6á, 9 - Difluoro- 11 â, 17, 2 1 - trihydroxy-1, 4 - pregnadiene-3, 20 - dione 21 - acetate 17 - butyrate . The Compound as also referr ed to as 1.02 shall mean the topical corticosteroid oph thalmic emulsion and/or suspension containing the Compound as an active ingredient for the treatment of ophthalmic diseases in humans only . Combination products containing the Compound and other active i ngredients, whether patented or not, are initially excluded from this definition, but may be included only with the express prior written consent of SENJ U, such consent not to be unreasonably withheld . Furth ermore, SENJU has the right to amend Article 10 of this Agreement in exchange for the grant of permiss ion to allow a patented combination product into th is definition, provided however, that for the term of this Agreement, as defined in Article 3, there shal l be a royalty on sales of combination products identical to those on the Product under Article 10 . After the term of this Agreement ends, the Parties shall negotiate in good faith for the future terms of such a grant