definiens: means all Contracts to which Seller or any of its Affiliates is a party or by which Selleror any of its Affiliates is bound, that relate primarily to the TBZ Business and/or the TBZ Products ( excluding anyemployment Contracts ), and including, for the avoidance of doubt, the ( A ) licence agreement between LifeHealth Limited andCambridge Laboratories Limited ( previously known as Cambridge Selfcare Diagnostics Limited ), dated December 10, 1998, asamended ( the ), ( B ) licence and consent agreement between Seller and LifeHealth Limited, dated asof September 22, 2006, as amended ( such agreement, together with the 1998 LifeHealth Licence, the ), ( C ) consultancy agreement between Cambridge Laboratories Limited and High Crane Limited, dated as ofDecember 20, 1996, as amended by the supplemental agreement, dated as of March 30, 2000, ( D ) second amended and restatedagreement dated November 18, 2005 between Seller and Prestwick Pharmaceuticals, Inc., as amended by the amendment letterdated September 12, 2008 among Seller, Prestwick Holdings, Inc. and Ovation Pharmaceuticals, Inc., and ( E ) first amended andrestated agreement for Canadian rights to Nitoman dated November 18, 2005 between Seller and PrestwickPharmaceuticals, Inc., as amended by the amendment letter dated September 15, 2008 among Seller, PrestwickPharmaceuticals, Inc. and [COMPANY] Americas Corp. ( such agreement, together with the agreement described in clause ( D ), the )