definiens: means any and al l of the following : ( a ) a Development Candidate for a [COMPANY] Target tha t is so designated under Section 2.5 hereof ; and ( b ) any Back - up Compound(s ) designated for such Development Candidate ; and ( c ) any other Small Molecule Compound that acts thr ough the same [COMPANY] Target : ( i ) that is made in the course of performing med icinal chemistry on or optimizing such Development Candidate and Back - up Compound(s ), or performing st ructure activity relationship activities using such Development Candidate, Back - up Compound(s ) or other Program Compounds active against such [COMPANY] Target ; provided that such Small Molecule Compound is first synthes ized within four ( 4 ) years after the expiration or earlier termination, in accordance with Section 2.5 .3.1, of Lexicon ’s obligations with respect to Rese arch Program Activities requested by [COMPANY] relating to such [COMPANY] Ta rget ; or ( ii ) that is Covered by a Valid Claim of any Pro gram Patent Rights ; and ( d ) any salts of any of the foregoing