definiens: shall mean any adverse event associated withthe use of any Product in humans, whether or not considered drug - related, that is, or is thought by the reporter to be, serious orassociated with relevant clinical signs or symptoms . Cadence shall be responsible for complying with all pharmacovigilanceobligations related to the Product in the Territory, including the maintenance of a safety database, and for the collection, evaluation and reporting of safety data regarding the Product for the Territory as required under Applicable Law . However, ifGrifols receives any Adverse Event notifications, [COMPANY] shall notify Cadence promptly following [COMPANY] ’ receipt of writteninformation of an Adverse Event and shall disclose to Cadence any and all information it has regarding that Adverse Event . Tothe extent an Adverse Event of which Cadence becomes aware implicates [COMPANY] ’ manufacturing or other processes at theFacility, Cadence shall inform [COMPANY] of such Adverse Event and shall disclose to [COMPANY] any information it has regarding thatAdverse Event