definiens: means:(a ) Patents that are Controlled by EPIZYME as of the Effective Date or during the Term that claim inventionsdiscovered, developed, invented, conceived or reduced to practice outside of the Collaboration, that ( i ) Cover thecomposition of matter or method of use of any Licensed Compound or Licensed Product or ( ii ) are otherwise necessary toresearch, Develop, make, use, offer for sale, sell, import and otherwise Commercialize ( but in the case of ( ii ), excluding suchPatents that Cover technologies that are not applied to the applicable Licensed Product prior to the [ * * ] anniversary of theEffective Date and are not included under clause ( b ) below ) any Licensed Compound or Licensed Product ; and(b ) Patents other than those included in the foregoing clause ( a ) that are Controlled by EPIZYME during the [ * * ] year period following the Effective Date that claim inventions discovered, developed, invented, conceived or reduced topractice outside of the Collaboration that are useful ( but not necessary ) to research, Develop, make, use, offer for sale, sell, import and otherwise Commercialize any Licensed Compound or Licensed Product, including Patents that claim formulation, delivery or manufacturing process improvements