definiens: shall mean all protocols, formulas, data, Inventions, know - how and trade secrets, patentable or otherwise with respect to ( i ) Hit Compounds, Lead Compounds, Nominated Compounds and/or Licensed Compounds, including without limitation, the titructure, activity and properties of such compounds and the gene t;et~ ; and/or gene signatures used for obtaining such data and information, ( ii ) protocoh and procedureti wied by [COMPANY] for lead optimization to the extent required for demon~;trating Biological Proof of Concept and/or Preclinical Proof of Concept, and ( iii ) the Target HTS ASiay * . ( m * . and ( iji ) *, in each case, resulting from the Research Program developed or invented solely by employees of [COMPANY] or other persons not employed by [COMPANY] acting on behalf of [COMPANY] ; provided that and for the purposes of clarity, Ea ) [COMPANY] Information and Inventions shall not include Avalon'~ ; protocob and/or proceduret ; for : lead optimization, tielecting and/or w;ing gene set~ ; and/or gene signatures