definiens: shall mean, in each caseto the extent permitted by the [ * ] under Section 6.4(d ) of the Agreement : ( A ) theAstellas Portion ( as defined below ) of the Added Indication DevelopmentCosts for ALS incurred by or on account of [COMPANY] ; plus ( B ) 100 % of anyother Development Costs for ALS ( e.g., country - specific development activitiesfor the [COMPANY] Territory and [ * ] ) incurred by or on account of Cytokinetics;minus ( C ) any portion of the Added Indication Development Costs for ALSincurred by or on account of [COMPANY] prior to Initiation of the PivotalRegistration Study, which [COMPANY] is required to solely fund but Cytokineticselects to co - fund under Section 1.3(c)(i ) of the Amendment ; and plus ( D ) anyportion of the Added Indication Development Costs for ALS incurred by or onaccount of [COMPANY] after Initiation of the Pivotal Registration Study, whichCytokinetics is required to co - fund but makes the deferral election, to theextent permitted by and in accordance with Section 1.3(c)(iv ) of theAmendment