definiens: ) to the Man ufacturing Agreement ( as defined below ) is effectiv e on the _ _ th day of April 2018, BETWEEN : 1 . INSYS MANUFACTURING, LLC, a company organized under the laws of the State o f Texas, with a place of business at 1333 S. Spectrum Blvd ., Suite 100, Chandler, AZ 85286 ( hereinafter referred to as ) ; and 2 . RENAISSANCE LAKEWOOD, LLC, a limited liabilit y company organized and existing under the laws of the State of Delaware, having its principal place of business at 1200 Paco Way, Lakewood, New Jersey, 08701 ( formerly known as [COMPANY] Lakewood, LLC ( hereinafter referred to as ) ) . RENAISSANCE and COMPANY are collectively referred to hereinafter as the BACKGROUND : 1 . INSYS THERAPEUTICS, INC . and RENAISSANCE entered in to a Manufacturing Agreement dated May 24, 2011, as amended October 29, 2013 ( ), April 30, 2015 ( ), August 18, 2015 ( ) and July 14, 2016 (, and as amended, the ) for the supply of Product