definiens: means the following : ( a ) with respect to Anacor, such efforts that are consistent with the efforts andresources normally used by Anacor in the exercise of its reasonable business discretion relating to the research anddevelopment progression of a potential pharmaceutical product owned by it or to which it has exclusive rights, with similarproduct characteristics as the Collaboration Compound, which is of similar market potential at a similar stage in itsdevelopment or product life as the Collaboration Compound, taking into account issues of patent coverage, safety andefficacy, product profile, the competitiveness of the marketplace, the proprietary position, the regulatory structure involved, profitability ( including pricing and reimbursement status achieved ), and other relevant factors, including technical, legal, scientific and/or medical factors ; and ( b ) with respect to [COMPANY], such efforts that are consistent with the efforts and resourcesnormally used by [COMPANY] in the exercise of its reasonable business discretion relating to a prescription pharmaceutical productowned by it or to which it has exclusive rights, with similar product characteristics as the Collaboration Compound or GSKDevelopment Compound ( as applicable ), which is of similar market potential at a similar stage in its development or productlife as the Collaboration Compound or [COMPANY] Development Compound ( as applicable ), taking into account issues of patentcoverage, safety and efficacy, product profile, the competitiveness of the marketplace, the proprietary position, the regulatorystructure involved, profitability ( including pricing and reimbursement status achieved ), and other relevant factors, includingtechnical, legal, scientific and/or medical factors