definiens: JHU / UFRF Agreement " shall mean the Standard Exclusive License Agreement With Sublicensing Terms, dated October 7, 2003, among Johns Hopkins University ( ), UFRF and Licensee, as amended by a First Amendment thereto and as further amended from time to time in effect . II 4 . Amendment to Section 2.2.2 of the License Agreement . Section 2.2.2 of the License Agreement is hereby deleted in its entirety and the following is substituted in lieu thereof : " 2.2.2 . In respect to Sublicenses granted by Licensee under Section 2.2.1, Licensee shall pay to UFRF an amount equal to what Licensee would have been required to pay to UFRF had Licensee sold the amount of Licensed Products sold by such Sublicensee . In addition, if Licensee receives any fees, minimum royalties, or other cash payments in consideration for any rights granted under a Sublicense, and such payments, fees or minimum royalties are not based directly upon the amount or value of Licensed Products sold by the Sublicensee, then Licensee shall pay UFRF [ fifteen percent ( 15 % ) ] of such payments in the manner specified in Section 3.6