definiens: means : ( i ) all patents and patent applications in existence as of the EffectiveDate or during the Term of this Agreement claiming generically or specifically the manufacture, use or sale of PTH, API orLicensed Product including, without limitation, a process for manufacturing PTH, API or Licensed Product, or anintermediate used in such process or a use of PTH, API or Licensed Product ; and ( ii ) any divisions, continuations, continuations - in - part, reissues, reexaminations, patents of additions, extensions or other governmental actions which extendany of the subject matter of the patent applications or patents in clause ( i ) above, and any substitutions, confirmations, registrations or revalidations of any of the foregoing, in each case which is owned or Controlled, in whole or part, by license, assignment or otherwise by Unigene as of the Effective Date or during the Term of the Agreement, to the extent Unigene hasthe right to license or sublicense such Unigene General Patent Rights, and subject to any limitations of any such license orsublicense . The current list of patent applications and patents encompassed within Unigene General Patent Rights is set forthin Appendix A. Appendix A shall be updated by Unigene on a semi - annual basis during the Term of the Agreement . For theavoidance of doubt, Unigene General Patent Rights shall include Unigene Inventions ( as defined in Section 6.1.1 ) and theUT Patent ( as defined below )