definiens: means, on a Royalty Product -by - Royalty Product and country - by - country basis, the first sale of such Royalty Product for end use or consumption of such Royalty Product in such coun try following receipt of Pricing Approval for such Roya lty Product in such country . First Reimbursed Sale excludes any sale or other distribution for use in any clini cal trial or other Development activity, promotiona l use ( including samples ), or for compassionate use or on a named patient basis . If, with respect to a parti cular country or jurisdiction at any given time, the applicable g overnmental authority in such country or jurisdicti on does not require reimbursement for pharmaceutical products t o be marketed or sold, then the First Reimbursed Sa le for a Royalty Product in such country or jurisdiction sha ll be deemed to have occurred upon the First Commer cial Sale of such Royalty Product in such country or jur isdiction