definiens: shall mean ( i ) either ( a ) [COMPANY] has initiated a follow - up clinicalstudy with a CAT19 1st Gen Product, or ( b ) [COMPANY] has initiated formal pre - clinical development of aCAT19 Binder Product ; and ( ii ) as soon as is reasonably practicable following marketing approval ofthe CAT19 Product in each of the relevant territories, [COMPANY] ( or its Sub - licensee ) has commencedsale of the CAT19 Product in either ( a ) the [ * * * ] ( if reimbursement has been granted in the [ * * * ] ) andone other Core Country or one of [ * * * ] or ( b ) at least any two of [ * * * ] or any of the Core Countries ( otherthan the [ * * * ] ), in the event reimbursement is not granted in the [ * * * ]