definiens: shall mean all biological targets, as described by a UniProt / SwissProt identifier, except those(i ) listed on Appendix 3.1.2 ( ) or ( ii ) with respect to which C4 T has, as of the date [COMPANY] provides the NominationNotice, ( A ) licensed or provided an option right to such target to a Third Party pursuant to an executed agreement with C4 T, or ( B ) initiated abona fide internal program at C4 T against such target as evidenced by having synthesized a Non- 16Calico Protein Degrader for such target and having an active program for such Non - [COMPANY] Protein Degrader against such target as evidencedby written records . C4 T will inform [COMPANY] as to whether a target is an Available Target within [ * * * ] of when [COMPANY] submits the NominationNotice . If the proposed target is an Available Target, then the parties shall discuss and within [ * * * ] determine whether to include such target inthe collaboration based on the relative merits of such target . If there is a disagreement as to whether to add such target to the collaboration, [ * * * ] shall have the tie - breaking vote . Any target added to the collaboration under this process shall be deemed a Collaboration Target