definiens: means any prodU(~t ( a ) that comprises and ( i ) [ a Factor VIla Compound, or ( ii ) an active ingredient of which is a small molecule and the mechanism of action of which is solely through inhibition of Factor VIla, ] ( b ) that ( i ) [ The manufacture, use, sale, offer for sale or import of which is covered by a claim of a [COMPANY] Patent, or ( ii ) is made by a process covered by a claim of a [COMPANY] Patent, or ( iii ) is acquired by [COMPANY] through [COMPANY] ' own internal research and development activities after the Effective Date and prior to the 3rd anniversary thereof . For purposes of clarification, a product · acquired by [COMPANY] from a third party will not be Factor VIla Product for purposes of this Section 1.28(b)(iii ) . ) 1.29 means the research activities conducted by [COMPANY] prior to the Effective Date directed to the discovery and development of small molecule Factor VIla inhibitors as therapeutic agents, including without limitation, compounds [ CRA~024783 ] and [ CRA-027819 ] .