definiens: ) . As used in this Second Amendment, shall mean the Original Agreement, as amended by the 2015 Letter Agreementand the First Amendment;Whereas, under the Agreement, [COMPANY] has an exclusive license from [COMPANY] to developand commercialize Program Compounds and Products for the PD-1 / VISTA Licensed Program(the ), including the Program Compound known as CA‑170,including any analogs, derivatives, prodrugs and polymorphs thereof, and any salts, crystallineforms, solvates, hydrates and stereoisomers of any of the foregoing ( collectively, ) andProducts containing CA‑170 ( ), worldwide, excluding India and Russia, andhas certain payment obligations to [COMPANY] with respect to such development andcommercialization;Whereas, under the Agreement, [COMPANY] has an exclusive license from [COMPANY] to developand commercialize Program Compounds and Products for the PD-1 / VISTA Licensed Program inIndia and Russia ; andWhereas, the Parties now wish to amend the Agreement to, among other things:(i ) expand [COMPANY] ’s territory with respect to CA‑170 and CA‑170 Products to all of Asia ; and(ii ) provide for [COMPANY] to conduct a clinical study of CA‑170 in combination with chemoradiationfollowed by maintenance CA-170, in Non - Small Cell Lung Cancer ( NSCLC ) in Aurigene’sterritory ; in each case, on the terms and subject to the conditions set forth herein