definiens: means all Patents ( ) and Know - How ( ) which ( i ) relate to a Project Gene designated as a Pre - Existing Project, ( ii ) are ( A ) owned, controlled or licensed by Lexicon as of the Effective Date or ( B ) created or acquired by Lexicon prior to expiration of this Agreement, and ( iii ) which either ( A ) are conceived or created during th e conduct of, or in connection with, First Pass Phenotypic Analysis or Advanced Phenotypic Analysis of a Project Gene, Pre - Clinical Development, Clinic al Development, any activities conducted under a Commercialization Plan, or [ * * ], or ( B ) relate to a product that [ * * ] ; provided in each case that Lexic on Pre - Existing Patents and Know - How shall not include ( a ) Lexicon Knock - Out Te chnology, ( b ) Lexicon Product Patents and Know - How, ( c ) [COMPANY] Gene Patents an d Know How, ( d ) Restricted Rights Project Patents and Know - How, or ( e ) general Patents that cover inventions that could be used for products other th an a Collaboration Product, including, without limitation, Patents covering man ufacturing or process ( including purification process ) inventions . Notwit hstanding the foregoing, Lexicon Pre - Existing Patents and Know - How shall exc lude Patents and Know - How specific to ( i ) [ * * ], ( ii ) [ * * ], and ( iii ) [ * * ]