definiens: shall mean those compounds ( i ) listed in Schedule 1.25, ( ii ) Additional LicensedCompounds, and ( iii ) COMT Inhibitor Compounds outside the scope of Merck Patent Rights developed by Licenseedirectly through the use of Merck Data or additional Merck Know provided to Licensee under Section 4.01, includingsalts, esters, metabolites, prodrugs, acid forms, base forms, steroisomers, racemates, tautomers, polymorphs, solvates, hydrates and crystalline forms thereof of either ( i ), ( ii ) or ( iii ) . For the avoidance of doubt, any compoundsoutside the scope of Merck Patent Rights having activity as COMT Inhibitor Compounds and resulting from thedevelopment and commercialization efforts by Licensee pursuant to this Agreement shall be considered LicensedCompounds