definiens: means ( a ) with respect to the first Contract Year, the period beginning on the Effective Date and ending on December 31, 2003 ( the ), and ( b ) with respect to each subsequ ent Contract Year, the twelve ( 12 ) month period beginni ng on the day following the end of the First Contra ct Year and each succeeding twelve ( 12 ) month period therea fter during the Research Program Term ( except that the last Contract Year shall end on the anniversary of the E ffective Date immediately following the effective d ate of any termination or expiration of this Agreement ) . Each Contract Year ( other than the First and last Contra ct Year ) shall be divided into four ( 4 ) comprised of successive three ( 3 ) month periods . In the First Contract Year, the first Contract Quarter shall end on the first day following the Effective Date that is the last day of a calendar quarter, and in the last Contract Year, the last Contract Quarter shall end on the a nniversary of the Effective Date immediately following the effect i ve date of any termination or expiration of this A greement