definiens: means the gross amounts invoiced for an Optioned A ntibody or Product for use in the Field by iTeos, its Affiliates and Licensees for sa les or other commercial disposition of such Optione d Antibody or Product to a Third Party purchaser, less the fol lowing : ( a ) trade and quantity discounts ( other than early pay cash discounts ) actually allowed with respect to such sales which effectively reduce the selling price and are appropriately deducted from s ales under appropriate accounting principles, consistently app lied ; ( b ) returns, rebates, chargebacks and other allowan ces actually allowed with respect to such sales ; 6 ( c ) retroactive price reductions that are actually allowed or granted ; ( d ) deductions to the gross invoice price of Optioned A ntibody or Product imposed by regulatory authorities or other governmental entiti es ; ( e ) sales ( such as VAT or its equivalent ) and excis e taxes, other consumption taxes, and customs duties ( excluding any taxes paid on the income from such sales ) except to the extent the selling perso n actually receives a credit or a refund for such taxes or dut ies ; and ( f ) bad debt, early payment cash discounts, transpo rtation and insurance