definiens: means, with respect to a Party ’s obligations under this Agreement, including toDevelop or Commercialize Product, those efforts and resources consistent with the usual practices of such Party in pursuingthe development or commercialization of its own pharmaceutical products that are of similar market potential and strategicvalue as such Product, taking into account all relevant factors including product labeling or anticipated labeling, present andfuture market potential, past performance of such Product and such Party ’s other pharmaceutical products that are of similarmarket potential, financial return, medical and clinical considerations, present and future regulatory environment andcompetitive market conditions, all as measured by the facts and circumstances at the time such efforts are due . Withoutlimiting the foregoing, Commercially Reasonable Efforts requires, with respect to such obligations, that the Party apply effortssufficient to carry out the given obligation in a diligent and sustained manner without undue interruption, pause, or delay