definiens: means, with respect to a Member, all Know - How Controlled by such Member on theEffective Date or during the term of the License Agreement ( except as otherwise expressly provided therein ) thatrelates to ( a ) miRNA Compounds or miRNA Therapeutics in general, ( b ) specific miRNA Compounds or miRNATherapeutics, ( c ) chemistry or delivery of miRNA Compounds or miRNA Therapeutics, ( d ) mechanism(s ) of action bywhich a miRNA Antagonist directly prevents the production of a specific miRNA or ( e ) methods of treating anIndication by modulating one or more miRNAs ; provided, however that in each case, ( i ) for any such Know - How thatinclude financial or other obligations to a Third Party, the provisions of Section 2.4 of the License Agreement willgovern whether such Know - How will be included as Licensed Know - How and ( ii ) Licensed Know - How does not includemanufacturing technology ( including but not limited to analytical methods )