definiens: means : ( i ) the Patents set out in Schedule 1 and a ny Patents claiming priority therefrom, or common priority thereto, whether or n ot in existence at the Effective Date ; ( ii ) any Patents filed by or in the name of CPF or its Affil iates, CRT or ICR on or after the Effective Date claiming any part of the Licensed Materials or thei r manufacture or use and/or Licensed Know - How ; ( iii ) any Patents filed by or in the name of CPF or its Affiliates, on or after the Effective Date cla iming analogues of Licensed Materials ( to the extent that their primary mechanism of action is through inhibition of CHK1, or their manufacture or use, ( i v ) any Patents filed by or in the name of CRT or ICR, on or after the Effective Date, solely to the extent that CPF is granted rights under such Patent s pursuant to the Upstream Licence Agreement, where s uch Patents claim analogues of Licensed Materials ( to the extent that their primary mechani sm of action is through inhibition of CHK1 ) or thei r manufacture or use, ; ( v ) any Patents claiming prior ity from the Patents described in ( i ), ( ii ), ( iii ) or ( iv )