definiens: means, as of the Fifth Amendment Effective Date, the Santaris Agreement and the T2Cure Agreement . Upon the select ion of a Replacement Target for microRNA-15/195, the Parties shall amend this definition as necessary to add all additional license agreements between Miragen and a Third Party entered into befo re the Effective Date pursuant to which Miragen has a sublicenseable license to Miragen Therapeutic IP th at covers such Replacement Target or Licensed Oligo s that directly and selectively modulate such Replace ment Target . Upon termination of a Target, the Part ies shall amend this definition to remove all license a greements between Miragen and a Third Party pursuan t to which Miragen has a sublicenseable license to in tellectual property that is no longer Miragen Therapeutic IP because it covers a member of the mi croRNA target family that was terminated or License d Oligos that directly and selectively modulate such member . ” 9