definiens: shall mean documented efforts : ( a ) that are consistent with those utilized by companies of similar size and type and at a similarstage of corporate development to LICENSEE, which companies have successfully developed therapeutic orprophylactic products similar to the proposed PRODUCTS IN CLASS described in the PLAN and/or services of a typesimilar to LICENSED METHODS described in the PLAN ; and ( b ) that are consistent with the interests of LICENSEE ’s stockholders and the development of aPRODUCT IN CLASS and/or commercial application of LICENSED METHODS and that constitute a prudent andcommercially reasonable use of LICENSEE ’s capital resources ; and ( c ) that are evidenced by a record of incurring MINIMUM DIRECT COSTS, which shall includethe RESEARCH SUPPORT, and additional documented expenditures appropriate to the stage of development of oneor more PRODUCTS IN CLASS and/or commercial application of LICENSED METHODS