definiens: means ( a ) the Patent Rights Controlled by Unigene or its Affiliatesas of the Effective Date or during the IP Term, including those that are listed in Schedule 2 to this Agreement, including theTechnology licensed to * * * under the * * * License Agreement as of the Effective Date, at such time as such Technologybecomes Controlled by Unigene during the Term, in each case that Cover and are Necessary for the manufacture of CalcitoninAPI, Amidating Enzyme or any Intermediates, ( b ) any continuations, continuations - in - part and divisionals of such PatentRights that are filed after the Effective Date and patents issuing from such applications, in each case to the extent claimingpriority from such Patent Rights, ( c ) all reissues, reexaminations, extensions and foreign counterparts of the Patent Rightsspecified in clauses ( a ) and ( b ) above that are issued or granted after the Effective Date and ( d ) any Patent Rights Controlledby Unigene or its Affiliates during the Term that Cover the Collaboration Improvements or the Unigene Sole Improvementsand which are Necessary or useful for the manufacture of Calcitonin API, Amidating Enzyme or any Intermediates