definiens: means any and all k now - how, trade secrets and proprietary technology that is Controlled by Symphony on the Effective Dat e and that relates to the Licensed Patents, Regulat ory Files, XL647, the Oncology Program, the Non - Oncology Progr am or Licensed Products, their use, formulation, preparation or manufacture, or which is necessary o r reasonably useful for the development, manufactur e, import, use or sale of Licensed Products, including without limitation, enhancements, manufacturing pr ocesses or protocols, writings, documentation, data, techni cal information, techniques, results of experimenta tion and testing, diagnostic and prognostic assays, specific ations, databases, any and all laboratory, research, pharmacological, toxicological, analytical, quality control, pre - clinical and clinical data, safety da ta, chemistry, manufacturing and control data and other informatio n and materials, whether or not patentable