definiens: means any indication or condition : ( a ) that is not a PrimaryIndication, Schizophrenia or Small Market Indication on the Execution Date ; ( b ) that is not an Associated CognitiveImpairment ; ( c ) that is, as of the Execution Date, neither included in DSM - IV or ICD-10 nor recognized as a distinctdiagnosable condition by general consensus in the medical community in the United States or Europe, and for whichno product has received Product Regulatory Approval from the FDA in the United States or the EMEA in Europe priorto the Execution Date ; ( d ) that either becomes included in DSM - IV, ICD-10 or any other Diagnostic Manual in a MajorMarket Country during the Term, becomes recognized as a distinct diagnosable condition by general consensus in theapplicable medical community in a Major Market Country during the Term or for which a product receives ProductRegulatory Approval from the applicable Regulatory Authority in a Major Market Country during the Term ; ( e ) for whichthe diagnosis requires a finding of Cognitive Impairment ; and ( f ) that [ * * * * * * * * ], as a Newly - Defined Cognitive Disorder