definiens: means ( a ) the Patent Rights Controlled by Unigene or its Affiliates asof the Effective Date or during the IP Term, including those that are listed in Schedule 2 to this Agreement, that Cover theLicensed Calcitonin Product and are Necessary for the development, testing, manufacture, use or sale of the LicensedCalcitonin Product, ( b ) any continuations, continuations - in - part and divisionals of such Patent Rights that are filed after theEffective Date and patents issuing from such applications, in each case to the extent claiming priority from such Patent Rights,(c ) all reissues, reexaminations, extensions and foreign counterparts of the Patent Rights specified in clauses ( a ) and ( b ) abovethat are issued or granted after the Effective Date and ( d ) any Patent Rights Controlled by Unigene or its Affiliates during theTerm that Cover the Collaboration Improvements or the Unigene Sole Improvements and which are Necessary or useful for thedevelopment, testing, manufacture, use or sale of the Licensed Calcitonin Product