definiens: shall mean ( i ) Know - How Enumeral owns or controls with respect to the First Antibody as of the Effective Date, ( ii ) K now - How Enumeral owns or controls with respect to t he Subsequent Antibody as of the Option Exercise Date ( as defined in Section 4.7 ) and ( iii ) the, Patent R ights Enumeral owns or controls claiming the First Antibo dy and, upon the Option Exercise Date, the Subseque nt Antibody ( including, without limitation, any patent s issuing on such patent applications, and any substitution, extension or supplementary protection certificate, reissue, reexamination, renewal, divi sion, continuation or continuation - in - part with respect t hereto during the Term ) ; and in the case of each cl ause ( i ), ( ii ) and ( iii ) only as such Know How and Patent Rig hts relate to the First Antibody and/or Subsequent Antibody, methods of using, administrating, manufac turing or formulating said First or Subsequent Antibody, useful or necessary for Pieris to develop and commercialize Products under this Agreement . T he Patent Rights as of the Effective Date are listed i n Exhibit A