definiens: means any composition ' of matter O"rartiCle ' of manufaCtui'e . omer::than MerCk Mtij'lOdy Phage Display, Materials, ContrOlled by, lisapplicable ; Merck or a MerCk Affiliate that comprises:(a1 any p < ilynucl ~ tille sequence encoding:(i ) an, ImiiJU!1ogIpbulin that i.scapable of belng · translocated to the pc:-riplasm of ahaeterialll'ost · cell ; andior(ii)'an Itnmunoglobulin that is operably linked to aba¢teriillly fune:- ! . tional signal sequenc<;;.artdlor ... '(iii ) an lmmUilo, gJobulin'that is capable ' ofbeing secreted an4lor /;Xcpressed in a ilrokary ~ e.and retain.itsbindingor other fwiction:.without subsequentrefolding;.or . .