definiens: shall mean computer software and know - how useful for the analysis, comparison, and curation of human nuclei c acid sequences ; and information related to such sequences ; and softwar e for the construction and maintenance of databases for the compilation o f such sequences and their associated information ; each developed from May 19, 1993 through the end of the INITIAL RESEARCH TERM . BIOINFORMATICS s hall include software for the prediction of the three - dimensional structure of proteins from primary sequence information but BIOINFORMATICS shall not include software for rational drug design based on such three - dimension al structure . To the extent BIOINFORMATICS includes software licensed f rom a THIRD PARTY such THIRD PARTY software is not included except to the extent that a party has the right to transfer to the other party such soft ware and its use and the other party agrees to pay any royalty owed to the THIRD PARTY for such software and its use