definiens: means an event, circumstance, effect or condition that individually of whentaken together with all other events, circumstances, effects or conditions has bad or would reasonably be expected tohave more than an immaterial adverse effect ( i ) on the business, assets, Liabilities, results of operations or financialcondition of the Business, other than any event, circumstance, effect or condition relating primarily ( x ) to the economy ingeneral, provided, that such event, circumstance, effect or condition does not have a materially disproportionate effecton the business, assets, Liabilities, results of operations or financial condition of the Business, or ( y ) in general to thepharmaceutical industry in which the Business operates and not specifically relating to the Products or the Business, provided, that such event, circumstance, effect or condition does not have a materially disproportionate effect on thebusiness, assets, Liabilities, results of operations or financial condition of the Business ; ( ii ) on any of the Products or thePurchased Assets ; or ( iii ) on the ability of EPI to perform its obligations under this Agreement, the Supply Agreement orany Related Agreement or on the ability of EPI to consummate the transactions contemplated hereby and thereby;provided, however, that the entry into the marketplace of a generic equivalent to any of the Products shall not be aMaterial Adverse Effect