definiens: means the gross amounts invoiced ( ) for sales of all Products by Ono and itsAffiliates and its permitted sublicensees ( each, a ) to Third Parties, less the following deductions, in each case tothe extent specifically related to a Product and taken by the Selling Person or otherwise paid for or accrued by the Selling Person ( ): ( i ) trade, cash, promotional and quantity discounts, and wholesaler fees ; ( ii ) taxes on sales ( such as excise, sales or use taxes or value added taxes ) to the extent imposed upon and paiddirectly with respect to the sales price ( and excluding national, sales or local taxes based on income ) ; ( iii ) freight, insurance, packing costs and other transportation charges for the Product [ * ] ; ( iv ) amounts repaid or credits taken by reason of damaged goods, rejections, defects, expired dating, recalls, returnsor because of retroactive price changes ; ( v ) charge back payments, rebates and returns granted to ( a ) managed healthcare organizations, ( b ) federal, stateand / or provincial and/or local governments or other agencies, ( c ) purchasers and reimbursers, or ( d ) trade customers, including, without limitation, wholesalers and chain and pharmacy buying groups, all only to the extent permitted by applicable law andregulations ; ( vi ) [ * ] ; and ( vii ) documented customs duties actually paid by the Selling Person