definiens: means the amount billed or invoiced fo~ CHI RON LicensedProducts sold by ROCHE or its Affiliates in the Region, less:(a ) Discounts actually allowed and taken;(b ) Amounts repaid or credited by reason of rejection or retum;(c ) To the extent separately stated on purchase orders, invoices or otherdocuments of sale, taxes levied on and/or other govemmental charges made asto production, transportation or insurance charges;(d ) The reasonable value of the instrument, instrument financing, consumables other than the CHIRON Ucensed Products in question ( includingwithout limitation sample preparation ) and service components of an operating orcapital lease for instrumentation on which the CHI RON Licensed Products areused ( collectively, ), for which the chargesare included in the price of the CHIRON Licensed Products purchased, providedthat the methods for detennining such value shall be proposed by ROCHE andsubject to CHI RON 's written consent, not to be unreasonably withheld;(e ) Charges for freight, handling and transportation paid by the selling entity, and(f ) Sales, use and value - added taxes and other similar taxes incurred andseparately stated on invoices