definiens: shall mean any and all Patent Rights ( other than thoselicensed under this Licence Agreement or Patent Rights Controlled by Alnylam)which, if claims covering subject matter of such Patent Rights issue, wouldrender the use, development, manufacture, sale, or other disposal of a LicensedProduct which is a CRT < PAGE > Licensed Product unlawful in the absence of a license to such Patent Rights froma Third Party, it being understood that Blocking IP shall include ( i ) anyintellectual property rights licensed from a Third Party other than CRT byNovartis pursuant to Section 4.4(e)(iii ) of the Collaboration Agreement, and(ii ) any Blocking RNAi Intellectual Property licensed from a Third Party otherthan CRT by [COMPANY] pursuant to Section 4.5 of the Collaboration Agreement, if, with respect to clauses ( i ) and ( ii ), such intellectual property rights wouldapply to a Licensed Product which is a CRT Licensed Product