definiens: shall mean the patent appl ications listed on APPENDIX H hereto ( including the OREXIGEN PROVISIONAL ), as well as an y patents hereafter issuing from such applications, together with all divisions, continua tions, continuations - in - part ( but only to the exten t that the subject matter of each such continuation - in - par t application is described in and enabled by the disclosure of said patent applications or other rel ated patent applications owned, in part or in whole by OREXIGEN, for which Xx . Xxxxx and/or Xx . Xxxxxxxx i s / are an inventor / inventors in accordance with appertaining patent law / regulations as a result of inventive contributions made in his / her position as an employee / employees of DUKE ), re - examinations, reiss ues, substitutions, or extensions ther eof and patent issuing therefrom in the United States and non -U.S. jurisdictions