definiens: means:(i ) in the case of Sangamo, the efforts and resources typically used by biotechnology companies similar in sizeand scope to Sangamo to perform the obligation at issue;(ii ) in the case of [COMPANY], the efforts and resources typically used by [COMPANY] and its Affiliates to perform theobligation at issue;in each case, which efforts shall not be less than those efforts made with respect to other products at a similar stage ofdevelopment or in a similar stage of product life, with similar developmental risk profiles, of similar market and commercialpotential, taking into account the competitiveness of the market place, the proprietary position of the products, the regulatorystructure involved, the profitability of the applicable products ( taking into account payments to Sangamo under thisAgreement ) and other relevant factors . Commercially Reasonable Efforts requires that the Party : ( a ) promptly assignresponsibility for such obligation to specific employee(s ) who are held accountable for progress and monitor such progress onan on - going basis, ( b ) set and seek to achieve specific and meaningful objectives for carrying out such obligation, and(c ) make and implement decisions and allocate resources designed to advance progress with respect to such objectives