definiens: shall mean all indications within a given sub - block of theInternational Statistical Classification of Diseases and Related Health Problems 10th Revision ( ICD-10 ) Version for2010, e.g. sub - block C61 With regard to other indications, each indication shallrequire treatment of a separate organ . For example, breast cancer and colon cancer are separate indications butmetastatic versus adjuvant breast cancer would be considered a single indication and not trigger a second set ofColumn 3 development event payments . Upon reaching development events, [COMPANY] shall timely notify Inovio anddevelopment event payments shall be paid by [COMPANY] to Inovio within ninety ( 90 ) days from occurrence of theapplicable event and receipt of an invoice from Inovio . If development of a given Oncology Product is discontinued forany reason, then the development event payments paid for such discontinued Oncology Product shall be creditableagainst development event payments due for the next Oncology Product in development