definiens: means all Information that ( a ) is ( 1 ) generated during the Term ( in the course of any activities with respect toSymproic or Naldemedine ) by or on behalf of, or if any of the foregoing Information generated in the course of any activities with respect toSymproic or Naldemedine otherwise becomes Controlled during the Term by, BDSI, any of its Affiliate(s ), and/or any BDSI Licensee, and(2 ) reasonably necessary or useful for the research, development, manufacture, use, importation, sale, development or commercialization ofSymproic or manufacture or use of Naldemedine ( or any analog or derivative thereof ), ( b ) is Controlled by BDSI, an Affiliate thereof, and / orany BDSI Licensee and incorporated into Symproic by or on behalf of BDSI, its Affiliate(s ), and/or BDSI Licensees ( and is not alreadyincluded in clause ( a ) above ), ( c ) is pharmacovigilance data or documentation generated during the Term in the course of any activities withrespect to specific to Symproic or Naldemedine by or on behalf of BDSI, any of its Affiliate(s ), and/or any BDSI Licensee ( and is not alreadyincluded in clause ( a ) or ( b ) above ), or ( d ) is otherwise used by BDSI, its Affiliate(s ), and/or BDSI Licensees to Develop, Manufacture, orCommercialize Symproic in the Field in the Territory during the Term ( and is not already included in clause ( a ), ( b ), or ( c ) above )