definiens: means the gross invoiced amount on sales of a Product by [COMPANY] and its Affili ates and its Sublicensees to Third Parties ( which will i nclude Distributors but not Sublicensees ) after ded uction of the following amounts : ( a ) [ * * * ] ( b ) [ * * * ] 1 A&R O PTION AGREEMENT ( c ) [ * * * ] ( d ) [ * * * ] ( e ) [ * * * ] ( f ) [ * * * ] ( g ) [ * * * ] ( h ) [ * * * ] ( i ) [ * * * ] ( j ) [ * * * ] In the event that a Product is sold in any country in the form of a combination Product containing one or more therapeutically active ingredient(s ), in addition t o the applicable Optioned Product Candidate or any related Subject Constructs, ( such product containing such o ther active ingredient, if sold separately, the ), Net Sales of such combination Product wi ll be determined as follows : [ * * * ] [ * * * ] [ * * * ] [ * * * ] [ * * * ] [ * * * ] [ * * * ] Net Sales will be calculated using [COMPANY] ’s in ternal audited systems used to report such sales as adjusted for any of items [ * * * ] above not taken into account in such systems . [ * * * ]