definiens: means any and all information provided by Helion related to M ASP-2 Historical Information or Proposals or relati ng to the following technology that was acquired, license d, developed or is owned and/or held by Helion : methods, antibodies and other agents and compositio ns for the inhibition of MASP-2 or for the treatmen t of MASP-2 deficiency disorders ; and includes without l imitation, research and development information, know - how, legal analysis, inventions, trade secrets, technical data, knock - out and knock - in mouse stra ins, gene expression profiles, behavioral and physiologi cal assays, phenotypes, cell lines, cellular, bioch emical and chemical assays, chemical structures, formulae, treatment methods, clinical trial design criteria, protocols, case report forms ( blank or including pa tient data ), investigators ’ brochures, † DESIGNATES PORTIONS OF THIS DOCUMENT THAT HAVE BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT FILED SEPARATELY WITH THE COMMISSION -20- drawings, designs, models, samples, processes, chem istry, manufacturing and controls information, regulatory information, and any type of product dev elopment, business or marketing plans or strategies or financial information