definiens: means ( 1 ) for FDA Approval without FDA Preferred Product LabelApproval, the FDA Approval Payment Amount, ( 2 ) for FDA Preferred Product Label Approval, the FDA Preferred ProductLabel Payment Amount, ( 3 ) for EMA Approval without EMA Preferred Product Label Approval, the EMA Approval PaymentAmount, and ( 4 ) for EMA Preferred Product Label Approval, the EMA Preferred Product Label Payment Amount, asapplicable ; provided that if FDA Preferred Product Label Approval is obtained at any time after FDA Approval is obtained, the applicable Regulatory Approval Payment Amount will be equal to the difference between ( i ) the FDA Preferred ProductLabel Payment Amount and ( ii ) the FDA Approval Payment Amount, and if EMA Preferred Product Label Approval isobtained at any time after EMA Approval is obtained, the applicable Regulatory Approval Payment Amount will be equal tothe difference between ( i ) the EMA Preferred Product Label Payment Amount and ( ii ) the EMA Approval Payment Amount