definiens: means each of ( i ) the Non - Exclusive License and Mat erial Transfer Agreement, dated as of February 5, 2007, by and bet ween REGENERON and ASTRAZENECA, ( ii ) the Non -Exclusive License and Material Transfer Agreement, dated as of March 30, 2007, by and between REGENERON and ASTELLAS, ( iii ) the Discovery and Pre clinical Development Agreement, the License and Collaboration Agreement, and the Stock Purchase Agreement, each dated as of November 28, 2007, between REGENERON and SANOFI - AVENTIS, ( iv ) with res pect to each agreement described in ( i ), ( ii ) and ( iii ) above, any amendments, modifications, or extensions thereof, and ( v ) all other agreemen ts in the FIELD OF USE entered into with these parties, i ncluding without limitation, any license or materia l transfer agreement with SANOFI - AVENTIS, including t hose agreements contemplated in sections 2.15, 2.16 and 2.17 of the November 28, 2007 Discovery an d Preclinical Development Agreement between REGENERON and SANOFI -AVENTIS