definiens: means, with respect to any Licensed Product, any and all research, development, pre - clinical, clinical and regulatory activities for such product, which may involve nonclinical studies, studies of chemistry, manufacturing and controls, clinical trials, regulatory affairs and other regulatory activities, quality of life assessments, pharmacoeconomics, post - marketing studies, label expansion studies, and furtheractivities related to development of such product to a stage ready for Commercialization thereof, but excluding anyBioCryst FDA Post - Marketing Commitments and any BioCryst - Led Regulatory Activities . and shall have their correlative meanings . ”(nn ) means, with respect to [COMPANY], a commitment by or on behalf of [COMPANY] touse reasonable, diligent, good faith efforts to Commercialize any Licensed Product consistent with [COMPANY] ’s practices indiligently and actively pursuing commercialization of its other pharmaceutical products at a similar stage of productlife, with similar safety and efficacy profiles, and of similar commercial potential, taking into account product labelingor anticipated labeling, present and future market potential, past performance of such Licensed Product, financialreturn, medical and clinical considerations, the extent of Legal Exclusivity relating to such Licensed Product, presentand future regulatory environment and competitive market conditions, all as measured by the facts and circumstancesat the time such efforts are due ( which practices shall be no less diligent or comprehensive than the practices whichare customary in the pharmaceutical industry with respect to, and shall include at least the same level of reasonable, diligent, good faith efforts as would be devoted by, other pharmaceutical companies of a similar size to [COMPANY] in theTerritory for such similar pharmaceutical products, taking into account the same factors described above )