definiens: shall mean ( a ) that certain United States Patent number 6,355,784, issued on March 12, 2002, entitled " Methods and compositions for the manufacture of halogenated anthracyclines with increased antitumor activity, other anthracyclines, halogenated sugars, and glycosyl donors, " ( b ) any and all foreign ( including International ) patents and patent applications that claim priority either directly or indirectly from US 6,355,784 or US Provisional Patent Application 60/089,162, ( c ) any provisionals, substitutions, divisionals, reissues, renewals, continuations, continuations - in - part, substitute applications and inventors ' certificates that claim priority either directly or indirectly from US 6,355,784 or US Provisional Patent Application 60/089,162, and ( d ) any foreign or domestic patents issuing from any of the foregoing patent applications