definiens: means, ( a ) for the Initial Project, the period be ginning on the Effective Date and, unlessearlier terminated in accordance with Section 12.2 ( b)(ii ) ( Project Termination ), ending on the 3.5 ( three an d a half ) yearanniversary thereof ; ( b ) for each Additional Projec t, unless earlier terminated in accordance with Sec tion 12.2(b)(ii)(Project Termination ), the four ( 4 ) year period beg inning on the date on which the JRC approves the Re search Plan forsuch Additional Project ; and ( c ) for the Agreement as a whole, the period beginning on the Effective D ate and endingat the conclusion of the last Research Term to expi re or terminate, as each such Research Term may be extended inaccordance with Section 2.2 ( Project Selection ; Research Term Extension ) or Se ction 12.2(a ) ( End of Research Term)or terminated in accordance with Section 12.2(b)(ii ) ( Project Termination )