definiens: shall mean any product [ th ~ t ( ans ] Covered by at least one ( 1 ) Claim of the Gene Therapy Patents [ issued in any of the Major Market CQuntriesQt{b).isa Parkinson 's Product and is produced pursuant to, embodies, incorpora ~ esoruses tbeGene Therapy Know - How . ] All such pharmaceutical products that are based on or incorporate a particular gene sequence ( or sequences ) shall be deemed to be a single Product . The Products include ( without limitation ) the Parkinson 's Product, the Factor IX Product, the Factor VIII Product and Lysosomal Storage Disorder Products . The Products specifically exclude all IL - lO Products . To avoid any confusion, [ Coverage ] for purposes of this definition [ ( notwithStanding the definition of Cover ) ] is determined as if [ manufacture, use and sale wereoccurfing ] in [ all Major Market Countries, ] regardless of the [ cQuntry(ies)Qf actual manufacture, use and sale . ] 1.70 shall have the meaning given in Section 4.4(a)(iii )