definiens: shall mean ~ e cost to Aurora and its Affiliates of raw materials, energy, labor ( salary and benefits ) and reasonable overhead charges relating to the manufacture of an item in accordance with generally accepted accounting methods consistently applied . If manufactured in whole or in part by a Third Party, the costs to be taken into account shall be the amount paid to such Third Party plus any of the aforementioned costs that are incurred in completing the manufacture and delivery . ] shall mean any material ha\'ing a biological or chemical activity, including, but not limited to, reagents, probes, structural genes, genetic sequences, promoters, enhancers, probes, linkage probes, vectors, plasmids, transformed cell lines, transgenic animals, proteins and fragments thereof, peptides, biological modifiers, antigens, antibodies, cell lines, antagonists, agonists, ~ . . .---- . ~- .. ---.--- . _ " - ..