definiens: shalllmeananyroyaltiesactuallypaidbyQuestDiagnostics toanyThirdPartyinconsideration foralicenseunderanyissuedpatentintheTerritoryownedbysuchThirdPartythatisnecessaryforQuestDiagnostics toexerciseitslicenserightshereunder(a)toperformtheServicessolelyattheFacilities, or(b)touse, offerforsaleandselltoThirdPartiestheServicessolelyintheTerritory, ineachcasesolelytotheextentsuchissuedpatentwouldbeinfringedbytheperformance oftheMaterniT2l PLUSTestbySequenom Laboratories asoftheEffectiveDate, oranyimprovements bySequenom totheMaterniT2l PLUSTestinthefuture