definiens: with respect to any Drug Product shall mean the gross amount invoiced by NOV ARTIS and any NOV ARTIS Affiliate, licensee or sublicensee for that Drug Product sold to Third Parties in bona fide, arms - length transactions, less§ quantity and/or cash discounts from the gross invoice price which are actually allowed or taken ; ( ii ) freight, postage and insurance included in the invoice price ; ( iii ) amounts repaid or credited by reasons of License . Development and Commercialization Agreement -Confidential . Page 5 rejections or return of goods or because of retroactive price reductions specificaJly identifiable to the Drug Product ; ( iv ) amounts payable resulting from Governmental ( or agency thereoO mandated rebate programs : ( v ) third - party rebates to the extent actually allowed : ( vi ) invoiced custom duties and sales taxes ( excluding income . value - added and similar taxes ) . jf any, actually paid and directly related to the sale ; and ( vii ) any other specifically identifiable amounts included in the Drug Product 's gross invoice price that should be credited for reasons substantially equivalent to those listed abov3all as determined in accordance with NOV ARTIS ' usual and customary accounting methods . which are in accordance with generally accepted accounting principles ( GAAP )