definiens: means any activities with respect to a LicensedCompound or Product conducted by either Party or any of its Affiliates, sublicensees or subcontractors at any time onor after the Effective Date during the Term consisting of ( a ) research or development for the purpose of, or in supportof, ( i ) obtaining, maintaining or expanding Regulatory Approval in the U.S. or EU or ( ii ) commercialization of anyProduct in the U.S. or EU, in each case ( ( i ) and ( ii ) ) pursuant to any Research Plan or Development Plan,(b ) commercialization of any Co - Promoted Product in the Co - Promotion Territory during the Co - Promotion Term,(c ) Medical Affairs Activities with respect to any Co - Promoted Product in the Co - Promotion Territory during the Co - Promotion Term or ( d ) for clarity, the manufacture of any Product ( including any intermediate thereof or any LicensedCompound or other material contained therein ) for use in any activities under clause ( a ), ( b ) or ( c )