definiens: means the aggregate amount of all gross revenue of total actual billing for sales of the Drug by UT or itsAffiliates to other Third Parties, less the following deductions : ( a ) trade, cash and quantity discounts and allowancesactually allowed and taken ; ( b ) any customs duties, taxes, or other governmental excise or charge upon or measuredby the production, sale, transportation, delivery, or use of the Drug and actually paid by UT or its Affiliates;(c ) amounts allowed or credited on rejections, defects, recalls, exchanges or returns or because of reasonable andcustomary chargebacks, refunds, rebates or retroactive price reductions ; and ( d ) freight, insurance and othertransportation and handling charges incurred in shipping the Drug to a Third Party . The Drug shall be considered soldwhen it is invoiced by UT or, if applicable, UT ’s Affiliates