definiens: means a synthetic DNA, RNA, or polypeptide encoding a non - naturally occurring fusionprotein comprising a transcription activator - like effector repeat binding domain, and an endonuclease domain ( eitherfunctional or non - functional ) or a portion of such endonuclease domain, wherein ( i ) the binding domain is engineeredfor recognition of a nucleotide sequence, ( ii ) the endonuclease domain or portion thereof is capable of cleaving ornicking DNA either as a monomer ( e.g. Tev ) or as a dimer ( e.g. Fokl ), and ( iii ) the manufacture, use, import and / orsale of the DNA, RNA or polypeptide is covered by one or Initials Two Blades Foundation : 5 Initials [COMPANY] Plant Sciences, Inc.:CONFIDENTIAL TREATMENT REQUESTED UNDER RULE 406UNDER THE SECURITIES ACT OF 1933, AS AMENDED