definiens: shall mean the product of ( a ) the average NHI Drug Price for a 50 mg vial of branded cisplatinat the time of Initial Regulatory Approval of the Licensed Product for the Initial Indication in Japan, multiplied by ( b ) 0.2682,and rounded to the next - 2 -highest whole number . The Parties acknowledge and agree that as of the Effective Date, the approved price in Japan for a 50 mg vial of ( i ) ( marketed by Nippon Kayaku ) is fifteen thousand nine hundred seventy Japanese Yen ( JPY 15,970),and ( ii ) ( marketed by Bristol - Myers Squibb ) is fifteen thousand eight hundred five Japanese Yen ( JPY 15,805),so the CDDP - based Price is ( x ) fifteen thousand eight hundred eighty - seven and five - tenths Japanese Yen ( JPY 15,887.5 ) ( i.e