definiens: means, with respect to a Party ’s obligations under this Agreement, including toDevelop, Commercialize or Manufacture the Product, those efforts and resources ( including, without limitation, expenditures)consistent with the usual practices of such Party in pursuing the Development or Commercialization of its own biologic orpharmaceutical products that are of similar status, such as commercial potential, the proprietary position of the product, theregulatory structure involved, the probably profitability of the applicable product, and other relevant factors includingtechnical, legal, scientific or medical factors . Without limiting the foregoing, Commercially Reasonable Efforts requires, withrespect to such obligations, that the Party : ( i ) promptly assign responsibility for such obligation to specific employee(s ) whoare held accountable for progress and monitor such progress on an on - going basis, ( ii ) set annual objectives for carrying outsuch obligations, and ( iii ) allocate sufficient resources ( including, without limitation, expenditures ) designed to advanceprogress with respect to such objectives