definiens: means the gross amounts invoiced by Lic ensee, its Sublicensees and Affiliates, for the sal e of Products to Third Parties in an arms - length tran saction in Canada, excluding sales for compassionat e use, named patient access and clinical trials, but solel y wherein the excluded sales are made at wholesale costs without profit, less the following deductions, whic h deductions will be determined on a Product - by - Pro duct basis and in accordance with GAAP, and except for those d eductions ( a ) for which Licensee ( or any of its Aff iliates ) is responsible pursuant to the APA, including pursuant to Sections 6.12(c ) and 6.12(d ) thereof and all Re tained Liabilities, and ( b ) that are otherwise attributabl e to the sale or distribution of Products by Licens ee prior to the Effective Date, as applicable : ( i ) [ * * * * * ] ; 2 [ * * * * * ] INDICATES MATERIAL THAT WAS OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT WAS REQUESTED . ALL SUCH OMITTED MATERIAL WAS FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUAN T TO RULE 24b-2 PROMULGATED UNDER THE SECURITIES EXCHANGE ACT OF 19 34, AS AMENDED