definiens: of a particular fact or other matter means : ( i ) with respect to any individual : ( A ) the actualknowledge of such individual concerning such fact or other matter ; and ( B ) the knowledge that a prudent individual wouldbe expected to discover or otherwise become aware of in the course of conducting a reasonable investigation concerningthe existence of such fact or other matter, and ( ii ) with respect to EPI or the Acquiror, the Knowledge concerning suchfact or other matter of ( 1 ) the officers of such Person, ( 2 ) the directors of such Person, and ( 3 ) the senior managers ofsuch Person with responsibility for, or supervision of, the relevant matters ; provided that under no circumstances shallKnowledge of EPI include any knowledge not actually known to such persons but imputed to such persons or EPI due toits relationship with Novartis or its representatives ; and provided, further, that none of such persons shall have anyobligation as a result of entering into ( or any provision of ) this Agreement, the Supply Agreement or any RelatedAgreement to make any inquiries of Novartis or its representatives regarding any matter