definiens: means the application of ongoing, consistent, diligent efforts and resources by Licensee, Novo oranother Sublicensee to Develop and Commercialize one or more Institute Licensed Products . It is understood that the level ofeffort and resources shall be consistent with its actions in respect of a product or compound owned or controlled by theapplicable party which the applicable party intends in good faith to Develop and Commercialize and which is of similarmarket potential and at a similar stage in its development or product life, taking into account, without limitation, with respectto a product issues of safety and efficacy, product profile, the proprietary position of the product, the then current competitiveenvironment for the product and the likely timing of the product ’s entry into the market, the regulatory environment of theproduct, and other relevant scientific, technical and commercial factors . Notwithstanding the foregoing, to the extent that theperformance of a party ’s responsibilities to use Reasonable Endeavors is adversely affected by another party ’s failure toperform its related responsibilities, such party will not be deemed to have failed to use its Reasonable Endeavors in performingsuch responsibilities