definiens: means proceeds received from Commercial Sales of L icensed Products by [COMPANY], its Affiliates or Sublicensees to Thir d Parties, after deducting ( to the extent actually incurred or reasonably estimated and accrued in accordance with Generally Accepted Accounting Principles in the Un ited States and to the extent not already deducted in th e amount invoiced ): ( i ) reasonable trade, cash and quantity discounts or rebates ( other than price discounts gr anted at the time of sale ), reasonable service allo wances and reasonable required agent ’s commissions, if any, al lowed or paid, ( ii ) credits or allowances actually given or made for rejection or return of previously sold pro ducts or for retroactive price reductions ( includin g Medicare, Medicaid, and/or discounts and similar types or reb ates and/or discounts ), ( iii ) taxes, duties or othe r governmental charges levied on or measured by the b illing amount ( excluding income and franchise taxes ), as adjusted for rebates and refunds, and ( iv ) charges actually incurred for freight and insurance directl y related to the distribution of Licensed Products ( excluding am ounts reimbursed by Third Party customers )