definiens: shall mean any proprietary, non - public information or materials, directed to theresearch, development, registration, manufacture, use, marketing or sale of Aminoglycoside Products which is developed priorto or during the term of this Agreement by or on behalf of Isis ( including by [ * * * ] under the Funding Agreement ( as definedin Section 3.6 ) ) . Aminoglycoside Program Know - How may include, without limitation : ( i ) all biological, chemical, pharmacological, toxicological, pharmaceutical, physical and analytical, clinical and safety data and information specificallydirected to Aminoglycoside Products ; ( ii ) compositions of matter, assays, development and validation reports and biologicalmaterials necessary or actually used for development, manufacture, use or sale of Aminoglycoside Products ; ( iii ) developmentdata and data and information necessary or actually used for manufacturing the Aminoglycoside Products ; and ( iv ) allregulatory applications, registrations licenses, authorizations, approvals and correspondences submitted to or received fromany regulatory authorities with jurisdiction over an investigational drug containing an Aminoglycoside Product