definiens: shall mean FTE costs and those out - of - pocket expenses incurred on a country -by - country basis and region - by - region basis, by either Party, other than Development Costs, before Regulatory Approval of Antegren or, as applicable, other Licensed Product, in such country, directly attributabl e to the carrying out of such Party 's obligations under the Commercialization Plan or an Annual Commercialization Plan / Budget, as applicable, in preparation for Commercialization in such country . Such expenses may include, without limitation, costs incurre d for professional education, Commercialization -related public relations, relationships with opinion leaders and professional societies, market research, health care economics studies, amounts paid Third Parties by a Party at reasonable rates pre -approved by the JSC, and establishment of the supply chain for the distribution and sale in such country, each to the extent allocable to Licensed Product and as described in the then current Commercialization Plan and an Annual Commercialization Plan / Budget . For p urposes of this definition, FTE costs shall be charged at the applicable FTE Rate