definiens: means : ( i ) with respect to a given Collaboration Target, any Third Party Compound that ( A ) is Directed to such Collaboration Target and ( B ) arose or arises out of any Acquired Third Party Development Program that is in - licensed or otherwis e acquired by [COMPANY] or any of its Affiliates prior to the date that is [ * * * ] after the date on which [COMPANY] exercised its Option with respect to ( x ) such Collaboration Target or ( y ) with respect to a Collaboration Druggable / LDD T arget, the Primary Campaign under which Repare has identified a Synthetic Lethal relationship between such Collaboration Druggable / LDD Target and the Cam paign Lesion(s ) that are the subject of such Primary Camp aign ( as applicable ) ; or ( ii ) with respect to a given Reverted Non - Option ed Target, any Third Party Compound that ( A ) is Directed to such Reverted Non- Optioned Target and ( B ) arose or arises out of any Acquired Third Party Development Program that is in -licensed or otherwise acquired by [COMPANY] or any of it s Affiliates prior to the date that is [ * * * ] after th e date on which [COMPANY] ’s Option expired or terminated unexercised with respect to ( x ) such Reverted Non - Optioned Targ et or ( y ) with respect to a Reverted Non - Optioned T arget that is a Druggable / LDD Target, the Primary Campaig n under which Repare has identified a Synthetic Let hal relationship between such Reverted Non - Optioned Tar get and the Campaign Lesion(s ) that are the subject of such Primary Campaign ( as applicable ) ; - 57 - Table of Contents in each case ( ( i ) and ( ii ) ) where, prior to the dat e on which [COMPANY] or its applicable Affiliate in - licen sed or otherwise acquired such Acquired Third Party Develo pment Program, the Third Party from whom [COMPANY] or suc h Affiliate in - licensed or otherwise acquired such Ac quired Third Party Development Program Independentl y Validated that such Collaboration Target or Reverte d Non - Optioned Target, as applicable, has a Synthet ic Lethal relationship with all Campaign Lesion(s ) that Repar e Validated as having a Synthetic Lethal relationsh ip with such Collaboration Target or Reverted Non - Optioned Target, as applicable, under this Agreement