definiens: means, subject to Sections 6.6 and 6.7, all Know- How that is Controlled by Presage or any of its Affiliates, as of the Effecti ve Date or at any time thereafter during the Term, and that is reasonably necessary or actually used in, the De velopment, manufacture, use, or Commercialization o f the Compound or Product . The Presage Know - How shall include all Know - How set forth on Schedule 1.42 . For clarity : ( a ) any and all Know - Ho w licensed to Presage under the Third Party License Agreement is included in Presage Know -How ; and ( b ) subject to the foregoing subclause ( a ), all 8 A request for confidential treatment has been made with respect to portions of the following document that are marked with [ * CONFIDENTIAL * ] . The redacted portions have been filed separately with the SEC