definiens: shall mean any improvement, modification or enhancement to the [COMPANY] Know - How or the inventions claimed in the [COMPANY] Patents ( and/or the practice thereof ), and any Information and intellectual property rights relating thereto, that the possessing Party has the right to disclose to the other Party without violating contractual obligations to a Third Party . For the avoidance of doubt, the following shall be owned by [COMPANY] and shall not comprise Improvements : ( i ) Information comprising the results of any assays or other screening or testing generated by [COMPANY] through use of the Accepted Cells Lines under the terms of this Agreement, and any Information developed based on evaluating or using such results ( which shall exclude, for clarity, any such Information that relates to the manufacture of such Accepted Cell Lines via the RAGE - VT method or use of same ) ; ( ii ) any methodology, process or tool, whether previously existing or created during the Term ( without use of an Accepted Cell Line ), that is proprietary to [COMPANY] and that [COMPANY] uses to generate the Information referred to in clause ( i ) ; and ( iii ) any invention based on, or improvement, modification, or enhancement of, the proprietary know - how of [COMPANY] that is created in connection with the subject Inatter of this Agreement and the use or practice of which does not involve the use of any [COMPANY] Technology