definiens: is defined as causes beyond the reasonable control of the Party, including acts of God ; changes in regulations or laws of any 82 CONFLDENTlAL government ; war ; civil commotion ; destruction of production facilities or materials by fire, flood, earthquake, explosion or storm ; labor disturbance s ; epidemic ; and failure of public utilities or common carriers . In such event that the ability of DURECT or [COMPANY] to perform its obligations under this Agreement, as the case may be, shall be so affected, the affected Party shall immediately notify the other Party of such inability and of the period for which such inability is expected to continue . The Party giving such notice shall thereupon be excused from such of its obligations under this Agreement as it is thereby disabled from performing for so long as it is so disabled and the 30 days thereafter . To the extent possible, each Party shall use all commercially reasonab le efforts to minimize the duration of any Force Majeure