definiens: means certain tangible biological materials thatarenecessaryfortheeffective exercise ofthePatent Rights, which materials aredescribed onExhibit A, aswellastangible materials thatareroutinely produced through useoftheoriginal materials, including, forexample, anyprogeny derived fromacellline, monoclonal antibodies produced byhybridoma cells, DNA orRNA replicated from isolated DNA orRNA, recombinant proteinsproduced through useofisolated DNA orRNA, andsubstances routinely purified from asourcematerial included intheoriginal materials ( such asrecombinant proteins isolated from acellextract orsupernatant bynon - proprietary affinity purification methods ) . These BiologicalMaterials shallbelisted onExhibit A, which willbeperiodically amended toinclude anyadditional Biological Materials thatMedical School mayfurnish toCompany