definiens: shall mean the criteria for advancement of a Collaboration Compound [ ... * * * ... ], which provisional criteria are included in the Initial Research Plan with respect to Programs directed against the InitialCollaboration Targets ( as such provisional criteria may be [ ... * * * ... ] in accordance with Section 2.1.6 ) and, with respect toPrograms directed against the Subsequent Collaboration Targets, as confirmed by the JSC with respect to each suchProgram in accordance with Section 2.1.6 . By way of guideline only, the Candidate Selection Criteria will typicallyinclude ( a ) data regarding the [ ... * * * ... ] of the Collaboration Compound and other [ ... * * * ... ] of the CollaborationCompound in [ ... * * * ... ] as well as a preliminary assessment of the [ ... * * * ... ], as well as evaluation of [ ... * * * ... ] models . Anassessment of [ ... * * * ... ] should be typically included with preliminary [ ... * * * ... ], [ ... * * * ... ] ; ( b ) the properties of theCollaboration Compound regarding [ ... * * * ... ] ; ( c ) assessment of the [ ... * * * ... ] ; and ( d ) a preliminary assessment of [ ... * * * ... ], ( provided, however, that nothing herein shall require Regulus to resolve any such issues if they are identified )