definiens: means U.S. Application No . 601121 ~588 and the corresponding PCT application WO 00/50043 and any continuing applicaiio l1s thereof, iIicluding continuatiohs, divls, iolls, sabstitutions, continuations:.in - part, and anypaients issued with te ~ p ~ atoany such . applications, " incliIding any reissue, ~e ~ eJ(a, mina#pii ~ ferie ~ al'or extension of my su6hpateiit,.and ' anyconflrDiat19tipatent orregisti ~ fion patent or patent o ~ additionoasedon ally suchpat ~ rif, and all f ~ r ~ i~~ounterparts of any of thefote ~ oihg .. '' Navia~}(Appris ~ tion : s''''Sh ~ rl ; iritlh\i~, . inter alia, the nati(}rtaipliase ~ppiibHti6ns~~ed, pn ~ CTJ ~ p ~ li8 ~ fi()~'\V0:'bO/50043 filed byWet'fSt'adii FltihgatY'I ~ t ~ ef ' Relnlblit'6'fKdrel!.::;"1 ' Russia and South Africa . ' ...... ', ..