definiens: means, in relation to an obligation of a Party un der this Agreement, efforts and resources comparable to thos e which an entity in the biotechnology or pharmaceu tical industry of similar resources and expertise as such Party generally uses to accomplish an equivalent t ask and, if used in relation to ( a ) Research of Compounds and P roducts and ( b ) the Development, Manufacture and Commercialization of a Licensed Product, efforts us ed by such an entity in relation to its own product s ( including internally developed, acquired and in - li censed products ) of a similar market potential or p rofit potential at a similar stage in development or prod uct life, based on conditions then prevailing and t aking into account, without limitation, issues of safety and e fficacy, Regulatory Authority - approved labeling, pr oduct profile, the competitiveness of alternative product s in the marketplace, the likely timing of the prod uct ’s entry into the market, the patent and other proprietary p osition, the likelihood of Regulatory Approval and other relevant scientific, technical and commercial facto rs