definiens: means those invoices issued by [COMPANY], its Affil iates and/or Sublicensees ( but not distributors who purchase the Product from [COMPANY], its Affiliates or Sublicensees ) for the sale of any Pro duct to Third Parties ( excluding sales among [COMPANY], Grifo ls ' Affiliates and Sublicensees ) but including any subsequent resale from [COMPANY], its Affiliates and Sublicensee s to an unrelated Third Party ), less the following deductions in accordance with IFRS, consistently applied : ( a ) normal and customary trade, cash and quantity disco unts actually allowed and properly taken directly with respect to sales of such Product ; ( b ) credits or allowances given or made for rejection or return of previously sold Products or for retroactive price reductions and billing errors ; ( c ) rebates and chargeback payments granted to managed health care organizations, pharmacy benefit managers ( or equivalents thereof ), national, state / provincial, local, and ot her governments, their agencies and purchasers and reimbursers, or to trade custome rs ; ( d ) costs of freight, carrier insurance, and other tran sportation and/or delivery charges directly related to the di stribution of such Product ; ( e ) taxes, duties or other governmental charges ( includ ing any tax such as a value added or similar tax, other than any taxes based on income ) directly levied on the sale, transportation, delive ry or use of a Product which is paid by [COMPANY] or measured by the billing amount f or such Product, as adjusted for rebates and refunds ; and 5 [ * ] = Certain confidential information contained in this document, marked by brackets, has been omitted bec ause it is both ( i ) not material and ( ii ) would be competitively harmful if publicly disclosed