definiens: means, with respect to a Licensed Product or Licensed Services, the gross amount invoiced by LICENSEE or its Affiliates on sa les or other dispositions of that Licensed Product or Licensed Services to third parties less the sum of : ( a ) trade, cash and quantity discounts or reba tes actually allowed or taken ; ( b ) credit or allowances given or made for rejection of or return of, previously sold Licensed Products or for retroactiv e price reductions ( including Medicare and similar types of rebates ) ; ( c ) charges for insurance, freig ht, and other transportation costs directly related to the delivery of the Licensed Product and invoiced by LI CENSEE, its Affiliates or Sublicensees ; and ( d ) Portions of this Exhibit, indicated by the mark were omitted and have been filed separately w ith the Securities and Exchange Commission pursuant to the Registrant ’s application requesting confidential tr eatment pursuant to Rule 406 of the Securities Act of 1933, as amended