definiens: shall mean a non - tethered intermediate compound of a tethered compound ( as that termis described in U.S. Patent number 6,335,155 B1 ), where such tethered compound ( i ) is either ( A ) a compound that binds to thepurine binding site of a Kinase, or ( B ) a compound that binds to the adaptive region of a Kinase ; ( ii ) was actually made orused by either Party alone or by both Parties jointly during the OCA Research Term in the course of activities directed to aTarget that was then a ( as defined in the OCA ) in the performance of the OCA Research Program inaccordance with the then - current OCA Research Plan ; and ( iii ) exhibits structure activity relationships and specific binding toone or more Kinase . For clarity, as used in this Section 1.38 shall mean that portion of the tetheredcompound which does not contain the linking or tethering moiety