definiens: means [ * * * ] 1.11 means any research information, technical information, technical data or other information that is ( a ) generated atDUKE by or under the supervision of one of the Inventors prior to the Term of this Agreement, ( b ) which is necessary for the practice of thePatent Rights, and ( c ) is not included in the Patent Rights . However, Know - how does not include any inventions, technology, cell lines, biological materials, compounds, probes, sequences, or methods or any uses thereof to the extent they are covered by Unexpired Claims ofissued patents or covered by Unexpired Claims of patent applications which are pending, or ( ii ) that are patentable but unpatented . Further, Know - how does not include any inventions, technology, cell lines, biological materials, compounds, probes, sequences, or methods or anyuses of any of the foregoing that DUKE can not provide to Licensee because of other legal obligations of DUKE existing as of the EffectiveDate, such as those arising out of sponsored research, clinical research, material transfer, license, option to license, confidentiality, or otheragreements