definiens: means each of ( a ) Ispronicline, ( b ) each Active+ Compound that is not a TerminatedCompound, ( c ) each Collaboration Compound for which [COMPANY] commences GLP Toxicology Studies asprovided in Section 5.1.2 or for which [COMPANY] does not commence GLP Toxicology Studies but Initiates aClinical Trial, ( d ) each Option Compound for which [COMPANY] exercises an Option, ( e ) each Licensed Derivativewith respect to ( i ) any such Option Compound made by or on behalf of [COMPANY] or its Affiliates or Sublicensees or(ii ) Ispronicline or any such Active+ Compound or Collaboration Compound made by or on behalf of ( A ) [COMPANY], [COMPANY] or any of their respective Affiliates or Sublicensees during the Research Program Term or the Tail Period or(B ) [COMPANY] or its Affiliates or Sublicensees after the Tail Period and ( f ) in each case ( ( a ) through ( e ) ), any saltform, polymorph, crystalline form, hydrate, solvate or formulation thereof