definiens: means, with respect to the efforts to be expended by a Party withrespect to any objective, those reasonable, good faith efforts to accomplish such objective as such Party wouldnormally use to accomplish a similar objective under similar circumstances . With respect to any efforts relatingto the Development, Regulatory Approval or Commercialization of an Agreement PDC or Licensed Product by aParty, generally or with respect to any particular country in the Territory, a Party will be deemed to haveexercised Commercially Reasonable Efforts if such Party has exercised those efforts normally used by suchParty, in the relevant country, with respect to a compound, product or product candidate, as applicable, owned orControlled by such Party, or to which such Party has similar rights, which compound, product or productcandidate is of similar market potential in such country, and is at a similar stage in its development or product lifecycle as the Agreement PDC or Licensed Product, taking into account all relevant factors in effect at the timesuch efforts are to be expended . It is expressly understood that the use of Commercially Reasonable Efforts mayresult in ceasing the Development, Regulatory Approval or Commercialization of an Agreement PDC or LicensedProduct . Further, to the extent that the performance of a Party ’s obligations hereunder is adversely affected bythe other Party ’s failure to perform its obligations hereunder, the impact of such performance failure will be takeninto account in determining whether such Party has used its Commercially Reasonable Efforts to perform anysuch affected obligations