definiens: means the amount to be paid over one ( 1 ) year by [COMPANY] to [COMPANY] to support one ( 1 ) FTE . The Annual FTE Rate will be ( Two Hundred Fifty Thousand Dollars ( $ 250,000 ) ] per year until the second anniversary of the Effective Date . Starting on the second anniversary of the Effective Date and continuing on each subsequent anniversary ( if any ) during the Research Tenn, this rate will be adjusted for Research support provided by [COMPANY] hereunder after such date by the percentage change, if any, in the Consumer Price Index described below as of the first day of the calendar month on or immediately preceding such adjustment date as compared to the index applicable to the most recent adjustment prior adjustment date ( August 1, 1999 shall be the reference date for the first adjustment ) . The index source will be the Consumer Price Index for All Urban Consumers -San Francisco Area, published by the Bureau of Labor Statistics of the United States Department of Labor ( or successor agency ) . Should an index covering the San Francisco area not then be available, then the national index will be used as the reference