definiens: means ( x ) if the relevant Licensed Product is the first Product or End Product manufactured byMedImmune ( or its Affiliates ), regardless of whether any given Product or End Product ismanufactured for [COMPANY] ( or its Affiliates ), Kolltan ( or its Affiliates ) or any Third Party, using theLB System Technology with respect to which Commencement of Phase 2 Clinical Study occurred, GBP [ * * ] ( £ [ * * ] ), ( y ) if the relevant Licensed Product is the second, third or fourth Product or EndProduct manufactured by [COMPANY] ( or its Affiliates ), regardless of whether any given Product orEnd Product is manufactured for [COMPANY] ( or its Affiliates ), Kolltan ( or its Affiliates ) or any ThirdParty, using the LB System Technology with respect to which Commencement of Phase 2 ClinicalStudy has occurred, GBP [ * * ] ( £ [ * * ] ), and ( z ) if the relevant Licensed Product is the [ * * ] or laterProduct or End Product manufactured by [COMPANY] ( or its Affiliates ), regardless of whether anygiven Product or End Product is manufactured for [COMPANY] ( or its Affiliates ), Kolltan ( or itsAffiliates ) or any Third Party, using the LB System Technology with respect to whichCommencement of Phase 2 Clinical Study has occurred, [ * * ] ( £ [ * * ] )