definiens: means the PTC Product - Specific Know - How andthe PTC Product - Specific Patent Rights.12 ActiveUS 169009360v.1Confidential 1.75 means all Know - How Controlled by PTCor its Affiliates on the Effective Date or at any time during the Term necessary to Develop orCommercialize a Product or disclosed by [COMPANY] to PTC and, in each case, specifically relates to(a ) the composition of matter of a Product or ( b ) methods of using a Product as a prophylactic ortherapeutic ; provided, however, Know - How Controlled by PTC or any of its Affiliates that ( i)consists of subject matter applicable to oligonucleotide compounds or products in general or ( ii)relates to an oligonucleotide compound that does not specifically modulate expression of aTarget via the binding, partially or wholly, of such compound to RNA that encodes a Target, willnot be considered PTC Product - Specific Know - How