definiens: means ( a ) primary IGFD, ( b ) severe primary IGFD, ( c ) Noonan ’s syndrome, ( d ) growth hormone deficiency, ( e ) adult growth hormone deficiency ( as approved by the FDA a nd consisting of two subgroups : adult and child onset ), ( f ) Adult Primary IGF-1 Deficiency, ( g ) idiopathi c short stature, ( h ) any other short stature indications, ( i ) Laron ’s Syndrome, ( j ) growth hormone insensitivi ty ( GHIS ), ( k ) any diseases or conditions which are approved f or sale by [COMPANY] or GNE, as of the Effective Date, for the treatment by growth hormone, and ( l ) all Excluded I ndications, which, for the purpose of this Agreemen t and 6 PORTIONS OF THIS EXHIBIT WERE OMITTED AND HAVE BEEN FILED SEPARATELY WITH THE SECRETARY OF THE COMMISSION PURSUANT TO AN APPLICAT ION FOR CONFIDENTIAL TREATMENT UNDER RULE 24b-2 OF THE EXCHANGE ACT ; [ * * * ] DENOTES OMISSIONS