definiens: means the following percentages of Net Sales of each Licensed Product and Licensed Combination : A. with respect to aggregate annual N~ Sales of any Li~-insed Product or Licensed CombinationsEight percent.1;.8%~of th ~ rst $ ~OO.OOO.OO2JOf such Net Sales during any calendar ~ ear,(!1ine percent ( 9%2jJf sucJl.:Net ! Sales betw~~n $ 100,000,001 a~ $ 250,000,000 during any calendar year and ~ n percent 10%2Jof such Net Salesl!n .excess of $ 250,000,000 during any calendar year ; provided, however, that each of the foregoing rates shall befreduced by one - haWwith respect to any Licensed Product or Licensed Combination which is based upon an OthfiI, Compound if the Net Sales in question aretor use other than modulating blood coagulati~ and B. with respect to aggregate annual Net Sales of any Licensed Combination, means the foregoing applicable percentage times the product which is calculated by mUltiplying the annual aggregate Net Sales of such Licensed Combination by a fraction ( not less than half ) whose numerator is the average of the sales prices during the concerned quaner for .the Licensed Product(s ) included in such Licensed Combination and whose denominator is the average of the sales prices during such quaner charged for the Licensed Combination . In the event there are no sales of such Licensed Product(s ) t the Earned Royalty for such Licensed Combination shall mean the applicable percentage times the product which is calculated by multiplying the aggregate aIUlual Net Sales of such Licensed Combination by a fraction ( but not less than half ) whose numerator shall be the cost of the Licensed Product(s ) included in such Licensed Combination and whose denominator is the sum of the numerator and the cost ( calculated on the same basis if manufactured ; otherwise on the basis of purchase price ) of all other Active Ingredients contained therein