definiens: sha11 meanusesofperfQrated microstructures within the respiratory tfac~ including withQut limitation . the nasal passage ; .provided, however, the Inhale ' Field sbail not include the use of penQrated microstructures in connection with the direct intratracheal or directpu1mona.ryadrninistration ( e.g., via bronchoscope or endotracheal tube)6f fluorochemicals or other liquids . Por clarity, t1l~ Iphale Field . includ¢s the administration of : perforated mb.1rost, ructurescontaining compounds by means of metered dose inhalertdry powder inhaler, flasa1·spray, or by nebtllization of perforated microstructures fonnulated with fluorochemicals as ~1,l$gendingagents~ provided that the quantities offluorochemicals so included itt such fo~~latiQA fornepulizatiOll do 110 t exceed that which is . commercially reasOnably necessary to prov : ideeffectlvedelivery of the aotiv¢ ! agf!nt . It is presently anticipated that thequantlties ' qf : fluorochemiltals to be used for nebuU ~ tiort of an active agent bYQron behalf of Inhale wilInot eXceedS inl ' per dose