definiens: sh 1 meanJany product comprising an I Antibody or Genetic Material en ( pding an Antibody wherein, in F:\A\Z2960\OOOl\GENP\LIC - CR9.SCF, i _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ -'L ! i I f I I ', " ' -I ' Ie t f -y CONFIDENTIAL fREA TMENT REQUESTED C ( iii ) properties that distinS * ish human and non - human and wherein1the cell lines aI~ not hybridoma lines antibodies, ( c ) Jcompositions, proc ~ ss -~~',-r ~ thods, or u ~ es, S ~ l~-ly -- dir ~ d c;i the production, modification, r expression of proteins in non­rodent transgenic animals;.j(d ) compositions of Antigens or ( methods to identify Antigens c methods to isolate Antigens ; ( e ) ajspecified use of polypep ides comprising -antibody variable f region sequences to a single i olated Antigen for the treatment of a particular disease indica ion, wherein the patentability of such use is not dependent in a~ way upon ( i ) Transgenic Products, ( ii ) Antibody Produc ~, or ( iii ) properties that I I \ distinguish human and non - huma I antibodies;J(f ) ( i)\compositions comprising a human cell that m rufactures and expresseslon its surface a non - naturally occurr ' ~g chimeric receptor mOleculeJ the chimeric receptor molecule haVifg an extracellular domain~ transmembrane domain, and a CyttPlasmic domainlwherein the I extracellular domain comprises ~n antibody variable regio ~ and I - ! LWherein at least one of the tra1smembrane domainl ~ o_r _ _ t_h _ _ e _ _ _ _ _ _ --, cytoplasmic domain is not deriv d from an immunoglobulin chai~ and ( ii)J Gene Therapy Vectors f r the delivery of Genetl . C I Materials encoding the chimeric receptor molecules described in clause ( f ) ( i ) of As used herein~ shall mean vectors within the Gene Therapy beld, and " ) ~- F:\A\22960\OOOI\GENP\LIC - CR9 .SCF . \, ; I I I I, i i l - I ! \ I !,