definiens: means any ( a ) direct or indirect acquisition of all or substantially all of the assets of aParty, ( b ) direct or indirect acquisition by a Person, or group of Persons acting in concert, of 50 % or more of thevoting equity interests of a Party, ( c ) tender offer or exchange offer that results in any Person, or group of Personsacting in concert, beneficially owning 50 % or more of the voting equity interests of a Party, or ( d ) merger, consolidation, other business combination or similar transaction involving a Party, pursuant to which any Person ownsall or substantially all of the consolidated assets, net revenues or net income of such Party, taken as a whole, orwhich results in the holders of the voting equity interests of such Party immediately prior to such merger, consolidation, business combination or similar transaction ceasing to hold 50 % or more of the combined voting powerof the surviving, purchasing or continuing entity immediately after such merger, consolidation, other businesscombination or similar transaction, in all cases where such transaction is to be entered into with any Person otherthan Isis, [COMPANY] or their respective Affiliates