definiens: means ( i ) with respect to the practice of the Isis Core Technology Patents and the Isis Manufacturing and AnalyticalPatents, ( A ) the prophylactic or therapeutic use or form of administration in humans or animals of a STAT3 Product orOncology Product for any indication, and ( B ) the prophylactic or therapeutic use or form of administration in humans oranimals of an [ * * * ] Product in the [COMPANY] [ * * * ] -Field, and ( ii ) with respect to the practice of the Isis Product - SpecificPatents, ( Y ) the prophylactic, therapeutic or diagnostic use or form of administration in humans or animals of a STAT3Product or Oncology Product for any indication, and ( Z ) the prophylactic, therapeutic or diagnostic use or form ofadministration in humans or animals of an [ * * * ] Product in the [COMPANY] [ * * * ] -Field