definiens: , as to each Clone . shall meant . I the Clone or the recombinant protein encoded thereby, or the Clone encoding a fragment of such protein with substantially the samb biological, activity as such protein, or the biologically active portion of such p ~ tein ; a product whereby Clone nucleic acid is ins ~ ed in~ a human host in order to Ihduco cells in such host to express the protein enc1ed by such nucleic acid for therapeutic benefit, or a product whereby Clone nudleiC acid is inserted ex vivo into human cells where such cells are then reimPlan~ into a human to express 5 ( c ) ( d ) ( e ) ( f ) ( g ) ( h ) CONFIDENTIAL the protein encoded by such nucleic acid for th ~ eutic benefit ( ) ; an oligonucleotide which binds to Clone mRNA in vivo to inhibit or block I protein production ( ) ;