definiens: means the total gross sales invoiced an d collected by the Marketers with respect to the Commercial Sale of the Product on a worldwide basis for use in any indication by the Marketers less th e aggregate of : ( i ) normal and customary returns, reb ates, recalls, chargebacks and discounts ( such as t hose granted or required pursuant to arrangements with M edicare, Medicaid and other third party payors ), in each case actually allowed and taken ; ( ii ) freight, tran sport and delivery, including insurance ( if separat ely identified on the invoice ) ; and ( iii ) any sales tax, value add ed tax, goods and services tax or any other tax, cu stoms or duties that may be imposed on the sale of the Produ ct, which taxes, customs or duties are included in gross sales invoiced, but not including any taxes assessed agai nst income derived from such sales