definiens: shall mean the amount invoiced in a given country by [COMPANY] or any Affiliate of [COMPANY] or any ( sub)licensee of [COMPANY] or any Affiliate of a sub(licensee ) for sales of a Royalty Bearing Product to a Third Party, and less the following to the extent accrued or credited and not paid or reimbursed by the Third Party : 18 ( a ) discounts ( including cash discounts and quantity discounts ), retroactive price reductions . charge - back payments and rebates granted to managed health care organizations or to federaJ, state and local governments, their agencies, and purchasers and reimbursers or to trade customers ; ( b ) credits or allowances accrued upon claims . damaged goods, rejections or returns of such Royalty Bearing Product, including Royalty Bearing Product returned in connection with recalls or withdrawals ; ( c ) shipping and insurance charges relating to the delivery of a Royalty Bearing Product ; ( d ) taxes or duties levied on, absorbed or otherwise imposed on the sale of such Royalty Bearing Product, including witbout limitation value - added taxes, or other governmental charges otherwise imposed upon the invoiced amount, as adjusted for rebates and refunds ; and ( e ) amounts repaid, credited or written off by reason of uncollectible debt and amounts written off on account of factoring of receivables, to the extent consistent with [COMPANY] ' business practices for the majority of its phannaceutical products, as detennined on a country - by­country basis