definiens: or means all research, discovery, pre - clinical development, clinical development, and regulatory activities with respect to Licensed Antibodies and Products, including optimization, non - clinical testing, pharmacology studies, toxicology studies, formulation, chemical analysis, bioanalytical analysis, material performancestudies ( such as measurements of stability, physical form, dissolution, or visual or spectroscopic analysis, and the like),manufacturing process development and scale - up ( including with respect to active pharmaceutical ingredient and drugproduct production ), quality assurance and quality control, technical support, pharmacokinetic studies, clinical studies, regulatory affairs activities, and manufacturing, use and importation in support of such activities, in each case to theextent- 4 - [ * ] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securitiesand Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended