definiens: ( may also be referred to as ) means any and all Patents ( including all claims and the entire scope of claim s therein ) in the Territory that are Controlled as of the Effective Date or thereafter during the Term by RAP T and/or any of its Affiliate(s ) and that claim the substance, composition, use or method of manufacture of the Co mpound and/or Product ( including, in each case, its composition, formulation, combination, product by p rocess, or method of use, manufacture, - 10 - preparation or administration ), or that would be ne cessary or reasonably useful for the Development, manufacture, use and/or Commercialization of Compou nd and/or Products in the Field as permitted under this Agreement . Subject to and to the extent as provided in Section 17.8 ( Assignment ), the use of in this definition shall exclude any Third Party that becom es an Affiliate due to such Third Party ’s or such T hird Party ’s Affiliate ’s acquisition of RAPT in a Change of Cont rol Transaction . As of the Effective Date, the RAPT Patent Rights in the Territory include the Patents listed in Exhibit B