definiens: means any and all of : ( A)(1 ) ( + ) -alpha - Methylbenze neethanamine, also known as, ( II ) carbamazepine ( 5H - Dibenz{b, f}az epine-5 - carboxyamide ), ( III ) guanfacine ( N-(Aminoiminomethyl)-2,6 - dichlorobenzeneacetamide ), ( IV ) lanthanum, and ( V ) mesalamine ( 5 - Amino-2 - hydroxybenzoic acid ), ( B ) any isomers, salts, solva tes, hydrates, polymorphs, esters, prodrugs, or met abolites of clause ( A ), and ( C ) any compound involving forming or breaking a bond or bonds with any of clause ( A ) or ( B ) where at least one prophylactic, therapeutic or diagnostic indication of such compound and/or its metabolite is substantially the same as that of any of clause ( A ) or ( B ), but excluding 10,1l - Dihydro-10 - oxo-5H - debenz[b, f]azepine-5 - carboxamide, also known as