definiens: means, with respect to a [COMPANY] Target : ( a ) a pharmaceutical product or medical therapy for deleting, inactivating, repairing, modulating the expression of, or inserting a functional version of, such [COMPANY] Target but not any other Target or loc us ( except, in the case of ( i ) the Initial Target, ( ii ) the Additi onal Target if it was a Reserve Target, or ( iii ) th e Additional Target if it was not a Reserve Target to the extent agreed by the Parties in writing in accordance with Section 2.4(a ) ), [ * * * ] ), which product or therapy ( i ) contains or em ploys at least one [COMPANY] ZF Compound which is known at the time of IND / CTA filing to Specifically Bind such Sh ire Target, and ( ii ) does not contain or employ ( A ) any other ZF Compound that, at the time of IND / CTA filing, is known after reasonable inquiry to Specifically Bin d a Target or other chromosomal location that is not such Shir e Target or within such [COMPANY] Target, or ( B ) any Do nor Nucleic Acid that encodes a protein ( including a functional portion of a larger protein ) that is neither a pro tein encoded by such [COMPANY] Target nor a functional version of the p rotein encoded by such [COMPANY] Target ; 8 * * * CONFIDENTIAL PORTIONS OMITTED AND FILED SEPARAT ELY WITH THE COMMISSION ( b ) a pharmaceutical product or medical therapy tha t contains or employs a human cell or tissue made using a product or therapy described in Section 1.92(a ) ; or ( c ) a diagnostic product or service for detecting t he sequence or allele of such [COMPANY] Target [ * * * ] ( t o the extent also contained in a Target that is ( i ) t he Initial Target, ( ii ) the Additional Target if it was a Reserve Target, or ( iii ) the Additional Target if it was no t a Reserve Target to the extent agreed by the Part ies in writing in accordance with Section 2.4(a ) ), which product or service ( A ) contains or employs o ne or more [COMPANY] ZF Compounds each of which Specifically Binds such Shi re Target and ( B ) does not contain or employ ( 1 ) an y other ZF Compound that Specifically Binds a Target or oth er chromosomal location that is not such [COMPANY] Targ et or within such [COMPANY] Target, or ( 2 ) any Donor Nucleic Acid that encodes a protein ( including a functional portion of a larger protein ) that is neither a protein encoded by such [COMPANY] Target nor a functional version of t he protein encoded by such [COMPANY] Target