definiens: means all Know - How that is ( a ) Controlled by [COMPANY] or itsAffiliates as of the Effective Date or during the Term, ( b ) solely with respect to such Know - Howarising after the Collaboration Term, is directly related to any [COMPANY] Technology utilized in theResearch Program ( or to any [COMPANY] Technology that existed during the Collaboration Term andwas suitable for use in the Research Program ) and ( c ) necessary or useful for the Exploitation ofany CAR Product Directed Against one or more Exclusive Targets, including, to the extentnecessary or useful, methods for ( i ) generating progenitor T Cells from donor material ; ( ii)generating and manufacturing cells of the T Cell lineage, including mature T Cells, hematopoietic stem cells, embryonic stem cells and/or iPSCs via a soluble or insoluble, bead - based system ; and ( iii ) generating and manufacturing cells of the NK Cell lineage