definiens: means Know - How that ( a ) is Controlled by [COMPANY] or its Affiliateson the Effective Date or thereafter during the Agreement Term ; ( b)(i ) is or relates to a Program DART or Licensed Product oran improvement, modification, enhancement or novel use of a Program DART or Licensed Product, or a Manufacturingprocess or formulation of a Program DART or Licensed Product or any improvement, modification or enhancement of aManufacturing process or formulation of a Program DART or Licensed Product ; or ( ii ) is used by [COMPANY] or its Affiliatesin the Research, Development, Manufacturing or Commercialization of a Program DART or Licensed Product and is disclosedto [COMPANY] or its Affiliates by or on behalf of [COMPANY] or its Affiliates pursuant to this Agreement ; and ( c ) is necessary oruseful to Research, Develop, Manufacture or Commercialize any Program DART or Licensed Product in the Field in theGilead Territory . [COMPANY] Information and Inventions excludes [COMPANY] ’ interest in the Joint IP and any Know - Howthat relates solely to any active pharmaceutical ingredient in a Combination Product other than a Program DART