definiens: means with respect to the efforts to be expended by a Party with respect to any objective under this Agreement, reasonable, good faith efforts to accomplish such objective as such Party would normally use to accomplish a si milar objective of such Party under similar circums tances, it being understood and agreed that with respect to th e Development or Commercialization of the Product, such efforts shall be similar to those efforts and resou rces commonly used by pharmaceutical or biopharmace utical companies, as applicable, of comparable size and re sources to such Party for a similar biological or pharmaceutical product owned by it or to which it h as rights, which product is at a similar stage in i ts development or product life and is of similar marke t potential taking into account efficacy, safety, a pproved labeling, the competitiveness of alternative produc ts in the marketplace, the patent and other proprie tary position of the product, and the likelihood of Regulatory Ap proval given the regulatory structure involved