definiens: - shall mean an initial human clinical trialof a pharmaceutical ~roduct that is conducted by or on behalf ofCorgentech its AffuJtes or sublicensees and that is required forMarketing Authoris ~ on, ood in which a product is tested in a limitednumber of either sicJ or healthy patients for the purpose ofestablishing dose ran . g and/or first indication of efficacy, and/or toexamine further asp of safety, of such product1.1.58 '' Phase III CIlnIcaI rials " - shall mean large scale, pivotalmulticentre, humm c · .cal trials of a pharmaceutical productconducted by or on b half of [COMPANY] its Affiliates or sublicenseesin a sufficient n of patients to establish safety or efficacy ofsuch product in the p .cular claim and indication tested andattended to support ting Authorisation