definiens: means, collectively, ( i ) that certain Phase 3 Clinical Trial conducted by Cell Genesys as of theEffective Date and entitled “ A Phase III Randomized, Open - Label Study of CG1940 and CG8711 Versus Docetaxel andPrednisone in Patients With Metastatic Hormone - Refractory Prostate Cancer Who Are Chemotherapy - Naïve, ” designatedinternally as VITAL-1 ( the ), and ( ii ) that certain Phase 3 Clinical Trial conducted by Cell Genesys as of theEffective Date and entitled “ A Phase 3 Randomized, Open - Label Study of Docetaxel in Combination With CG1940 andCG8711 Versus Docetaxel and Prednisone in Taxane - Naïve Patients With Metastatic Hormone - Refractory Prostate CancerWith Pain, ” designated internally as VITAL-2 ( the )