definiens: shall mean either one of the following and shall mean both of the following small molecules that binds toand inhibits the Exclusive Targets and that are specifically disclosed and generically described in ( a ) Nerviano Patent CaseNMS 030 such as the molecule known internally at Nerviano as Nerviano - E628 with the chemical structure set forth onExhibit 1.3, together with its pharmaceutically acceptable salts, esters, ethers, hydrates, isomers, mixtures of isomers, complexes or derivatives, and ( b ) the small molecule described in Nerviano Patent Case NMS 017 such as the moleculeknown internally at Nerviano as Nerviano - P360 with the chemical structure set forth on Exhibit 1.3, its pharmaceuticallyacceptable salts, esters, ethers, hydrates, isomers, mixtures of isomers, complexes or derivatives