definiens: means Net Sales less ( i ) [ * * * ] means, the gross invoiced sales of a Product to al l customers less ( i ) the cost of the Product, including freight in, duty, customs, shipp ing and all related direct costs of acquiring the Product ; ( ii ) chargebacks ; ( iii ) freight and insura nce charges ; ( iv ) trade discounts, credits or allowances ; ( v ) costs of replacements, returns, rec alls or rebates ( including but not limited to group 1 purchasing organization fees and rebates ) ; ( vi ) dis counts or rebates or other payments required by law to be made under Medicaid, Medicare or other go vernmental special medical assistance programs ( vii ) wholesaler service charges ; and ( vii i ) sales, excise or value added taxes paid on or in relation to sales of the Product, all as calculated in accordance with United States Generally Accepted Accounting Principles, or US GAAP