definiens: means with respect to a Party ’s research, development, and commercialisation of Licensed Products, the level of effortsand resources such Party would typically exert in similar circumstances pursuing the development and commercialisation of a similarproduct with similar market potential taking into account the stage of development or commercialisation, market potential and market size, the product life cycle, the risk of development or commercialisation of the Licensed Product, the cost effectiveness of efforts or resources, the competitiveness of alternative products that are or are expected to be in the marketplace, the scope and duration of patent rights or otherproprietary rights related to the Licensed Product, and the profitability of the Licensed Product [ * * * ] . The efforts and resources of eachParty ’s respective Affiliates and Sub - Licensees shall count towards that Party ’s own Diligent Efforts . Notwithstanding the foregoing, theexercise of diligence by the Licensee shall be determined by judging the Licensee ’s commercially reasonable efforts taken as a whole [ * * * ]