definiens: means those FTE costs of Sanofi or its Affiliates and direct out - of - pocket costs ( wherever incurred ), including costs for independen t contractors engaged as permitted under this Agree ment, recorded as an expense by Sanofi or its Affiliates that are specifically identifiable or reasonably al locable to the sales and marketing of the Optioned Product, includ ing a reasonable allocation of Sanofi ’s global mark eting personnel and marketing personnel specifically allo cated to the United States and out - of - pocket costs incurred with respect to such personnel, all such costs as c onsistently applied across all of Sanofi ’s commerci al products, with respect to the following activities : a ) activities directed to the advertising and marketin g of the Optioned Product ; b ) launch meetings ; c ) advertising and public relations agencies, inclu ding development and distribution of selling and advertising and promotional materials relating to t he use of a Product, [ * ] = Certain confidential information contained in this document, marked by brackets, is filed with t he Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended