definiens: means the Patents in the Territory Controlled by [COMPANY] as of the Effective Date or [COMPANY] or any of i ts Affiliates at any time during the Term that : ( a ) claim the composition of matter of a Licensed Compound or a P roduct, including in the Combination Regimen that i ncludes [ * * * ] itself ), ( b ) would be infringed by Developing or Commercializing a Licensed Compound or any Prod uct, including as a component of the Combination Regimen ( [ * * * ] ) but for the license granted hereunder, ( c ) would be infringed by use of [ * * * ] in a Combination Regimen but for the license granted hereunder or ( d ) are ot herwise necessary or reasonably useful for Zai to Develop a nd Commercialize Licensed Compounds and Products in accordance with this Agreement, including as a comp onent of the Combination Regimen ( [ * * * ] )