definiens: means any Patent Rights containing one or more claims that cover the composition ofmatter of a Named Compound or Licensed Product, or the manufacture or formulation of the foregoing, or use of aNamed Compound or Licensed Product for a Named Indication, or any Patent Rights otherwise necessary or usefulfor the Development, manufacture, use or Commercialization of any Licensed Product for a Named Indication, whichare Controlled by [COMPANY] as of the Effective Date or come within [COMPANY] ’s Control during the Term ( other than PfizerPatent Rights pursuant to the licenses granted hereunder ), including any Patent Rights claiming [COMPANY] Improvementsor Joint Improvements . For purposes of this Agreement, [COMPANY] Patent Rights shall not include the * * unless Adolorgrants [COMPANY] a sublicense to the * * pursuant to a separate agreement or an amendment to this Agreement . A list ofAdolor Patent Rights as of the Effective Date, which list may be updated from time - to - time, is set forth on Schedule1.8