definiens: means:(a ) in the case of Sangamo, the efforts and resources typically used by biotechnology companies similar insize and scope to Sangamo to perform the obligation at issue;(b ) in the case of [COMPANY] Idec, the efforts and resources typically used by [COMPANY] Idec and its Affiliates toperform the obligation at issue;in each case, which efforts shall not be less than those efforts made with respect to other products at a similar stageof development or in a similar stage of product life, with similar developmental risk profiles, of similar market andcommercial potential, taking into account the competitiveness of the market place, the proprietary position of theproducts, the regulatory structure involved, regulatory authority - approved labeling, product profile, the profitability ofthe applicable products ( taking into account payments to Sangamo under this Agreement ), issues of safety andefficacy, the likely timing of the product ’s entry into the market, the likelihood of receiving Marketing Approval andother relevant scientific, technical and commercial factors . Commercially Reasonable Efforts requires that the Party:(i ) promptly assign responsibility for such obligation to specific employee(s ) who are held accountable for progressand monitor such progress on an ongoing basis, ( ii ) set and seek to achieve specific and meaningful objectives forcarrying out such obligation, and ( iii ) make and implement decisions and allocate resources designed to advanceprogress with respect to such objectives