definiens: mean any invention, discovery, development or mod ification by Loxo or on behalf of its Affiliates or a [COMPANY] Party, with respect to a Licensed Compound or Licensed Product or relating t o the Exploitation thereof, whether or not patentable, that is conceived, reduced to practice, discovere d, developed or otherwise at any time in the course of and as a result of the conduct of the activities contemplated by this Agreement, which is reasonably useful for the Exploitation of a Licensed Compound or Licensed Product, including any enhance ment in the efficiency, operation, manufacture, cost of manufacture, ingredients, preparation, pres entation, formulation, means of delivery or dosage, use, or methods of use or packaging of such License d Compound or Licensed Product, any discovery or development of any new or expanded indications for such Licensed Compound or Licensed Product, any discovery or development that improves the stab ility, safety or efficacy of such Licensed Compound or Licensed Product or would, if Commercia lized, replace or displace such Licensed Compound or Licensed Product for the indication for which such Licensed Compound or Licensed Product has received Marketing Authorization or for which a Party is seeking Marketing Approval in the Field