definiens: shall mean either of the nucleosides, the [ ili~{j ~ fl * is identified on Schedule I to the Research Plan as of the Effective Date andj shall be specified by Idenix in writing to Metabasis within J~ after the Effective Date, subject to written approval by Metabasis, not to be unreasonably withheld or delayed, and Schedule I to the Research Plan shall be automatically amended to include [ ~'t.!~~~~~~~~<iV!~~~~~~§t < iV~~ ] ~ 1.22 shall mean ( a ) Patents with claims or portions thereof, to the extent directed to any Invention that is an Idenix Nucleoside or Collaboration Compound or a 532464 v2 / SD 3 . * * * Confidential Treatment Reauested method of making or using an Idenix Nucleoside or Collaboration Compound, where such Patents are Controlled by Idenix as of the Effective Date, ( b ) Patents with claims or portions thereof, to the extent directed to any Invention that is an Idenix Nucleoside or a method of making or using an Idenix Nucleoside, where such Invention first becomes Controlled by Idenix during the Research Term ( provided that any such Patent with the same disclosure as a Patent described in subsection ( a ), such as a renewal, division, continuation ( in whole ), or request for continued examination ( RCE ), reissue, reexamination or the like, will be included in subsection ( a ) rather than subsection ( b » and ( c ) Patents with claims or portions thereof, to the extent directed to any Invention that is a Collaboration Compound or a method of making or using a Collaboration Compound, where such Invention first becomes Controlled by Idenix after the Research Term but prior to the First Commercial Sale of any Product that contains such Collaboration Compound . Notwithstanding the foregoing, subsection ( b ), does not include any claims of such Patents or portions thereof to the extent directed to any such Invention that is a Collaboration Compound or a method of making or using a Collaboration Compound . For purposes of clarity, Idenix Patents do not include Metabasis Patents . The Idenix Patents existing . on the Effective Date are listed on Exhibit C