definiens: shall mean ( a ) the U.S. provisional patent application Serial No . 601058,573 filed on September 11, 1997 and assigned to JHU entitled " Use of Multivalent Chimeric Peptide - loaded, MHC / Ig Molecules to Detect, Activate or Suppress Antigen - Specific T Cell - Dependent Immune Responses " ( JHU DM-3302 ) and U.S. provisional patent application, Serial Number 601014,367 filed March 28, 1996 and U.S. patent application Serial Numbers 08/828,712 and PCTIUS97/04694 both filed March 28, 1997 and assigned to JHU entitled ( JHU DM-3085 ) ( hereinafter the ), ( b ) any invention disclosed and claimed therein, and all continuations, divisions, reissues and extensions based thereon, and any corresponding foreign patent applications, and any patents, patents of addition, or other equivalent foreign patent rights issuing, granted or registered thereon and ( c ) all new inventions or improvements conceived and or reduced to practice by JHU faculty and employees ( solely or jointly with others ) while performing Research under the -2 - COLLABORATION RESEARCH AGREEMENT and any other existing or future patent, patent application and provisional application claiming either any INVENTION or joint INVENTION that is developed under the COLLABORATIVE RESEARCH AGREEMENT . Improvements made specifically to CCT 's proprietary High Density Microparticles ( ) by JHU while performing Research shall not be considered PATENT RIGHTS or INVENTIONS and at all times shall vest in CCT, provided, however, that royalty obligations related to PATENT RIGHTS set forth herein shall not decrease because a HDM is used with or attached to materials or utilizes methods covered by PATENT RIGHTS