definiens: means Know - How owned or Controlled by Reata or its Affiliates as of theEffective Date or during the Term regarding or specifically related to a Licensed Compound or Licensed Products, orthe manufacture, development, commercialization or use thereof . For the avoidance of doubt, Know - how regarding orspecifically related to Reata ’s ( i ) research activities, ( ii ) medicinal chemistry efforts, or ( iii ) other efforts aimed atidentification or characterization of, or synthesizing or optimizing, molecules, other than with respect to LicensedCompounds in all such cases of ( i ), ( ii ) and/or ( iii ), are excluded from 1.1.47 means all patents and patent applications owned or Controlled by Reata or itsAffiliates as of the Effective Date or during the Term which claim, or, but for the license granted herein, would beinfringed by, a Licensed Compound or Licensed Products, or the manufacture, use or sale thereof, including thepatents and patent applications listed on Exhibit A attached hereto, and any and all substitutions, divisionals, continuations, continuations - in - part, reissues, renewals, registrations, confirmations, re - examinations, or extensions ofsuch patents and patent applications, and any foreign counterparts of the foregoing, and any patents issuingtherefrom within the Territory