definiens: means a decision with respect to the following issues : ( a ) the manner by which ARCHEMIXconducts the [ * * * ] against [ * * * ] ; ( b ) whether ARCHEMIX is to incur any [ * * * ] under the Research Program except for [ * * * ] that are included in any Annual Research Plan by mutual agreement of the Parties and without TAKEDA exercising thedeciding vote under Section 2.1.6 to cause its inclusion ; ( c ) whether ARCHEMIX is [ * * * ] any ARCHEMIX AdditionalActivities ; ( d ) whether ARCHEMIX is to incur any [ * * * ] in the performance of [ * * * ] and/or ARCHEMIX AdditionalActivities except for [ * * * ] that are included in the Annual Research Plan by mutual agreement of the Parties and withoutTAKEDA exercising the deciding vote under Section 2.1.6 to cause its inclusion ; and ( e ) the number of FTEs to be providedby ARCHEMIX in each Annual Research Plan to the extent such number of FTEs exceeds [ * * * ] FTEs per Fiscal Year