definiens: means all Patents invented jointly by Isis and [COMPANY] at any time during theTerm Covering ( i ) the composition of matter of a Lipid Drug or Product, or ( ii ) methods of using a Lipid Drug or Productas a prophylactic or therapeutic ; provided however, Patents jointly invented by Isis and [COMPANY] that include onlyclaims that are directed to ( y ) subject matter applicable to oligonucleotide compounds or products in general in atarget independent manner including Conjugate Technology or ( z ) an oligonucleotide compound that does notspecifically modulate expression of a Lipid Target via the binding, partially or wholly, of such compound to RNA thatencodes Lipid Target, will not be considered Joint Product - Specific Patents, and in the case of ( y ) and ( z ), suchPatents will be considered Joint Core Technology Patents