definiens: means ( a ) a compound ( or a prodrug or metabolite thereof ) other than a Memory Compound or Compound 3454, which is : ( i ) a nicotinic alpha-7 agonist [ or allosteric modulator ] that is conceived, acquired or Controlled by either 2 CONFIDENTIAL TREATMENT IS REQUESTED FOR INFORMATION IN BOLD AND BRACKETS Party prior to the date hereof and ( ii ) has previously been demonstrated by either Party to have Threshold Activity prior to the Effective Date or during the Extended Period [ provided that if a compound conceived, acquired or Controlled by [COMPANY] prior to the date hereof is not an Included [COMPANY] Compound, such compound shall not be a Collaboration Compound ] or ( b ) a compound ( or a prodrug or metabolite thereof ), other than a Memory Compound or Compound 3454, which is : ( i ) a nicotinic alpha-7 agonist [ or allosteric modulator that ] is conceived, acquired or Controlled by either party after the date hereof and ' prior to the end of the Extended Period and ( ii ) demonstrated by either Party to have Threshold Activity prior to the end of the Extended Period