definiens: ~ luis the meaning ..... fonlt in Section 11,3 1.49 Mlndic4llon~ means lhe tmllment or prevention of . go.:nerally ackllOwledgr : d di.seuc or medical condition •• signifocant rnanifesc . tion of I disease or medi<:~l condition, 01, of different medicil « : lIIdilion, in pBlients having th~ salTlC underlying di : oea : oe shall not be ImltOO as the $ lime Indication ( for eXlimple the trealmem of cardiac disease ami n : tinapalhy in palicllts with diabetes ), while the ( ", annen ! of lhe $ lime condition in variantS of a sillgle .lise ....... & hRlI be treatoo II the same Indication ( rOl " example the treatment of elev.too blood phenylalanin e in c!IIUical PKU, mctlc!n.te PKU, and hy ~ rphcny lalaninemi . ( HPA ) are all one Indication )