definiens: means, with respect to Protagonist, a Change of Control in which the Acquirer : ( A ) has, a s of the time of such Change of Control a field sales force in the United States th at promotes any pharmaceutical product for any IBD Indication ( as defined in Secti on 6.7.2 ), ( B ) has entered into or become the subject of a corporate integrity agreeme nt, settlement or order with or of the Office of Inspector General, U.S. Department of Health and Human Services, or another Governmental Authority, relating to marketi ng or commercialization of pharmaceutical products, ( C ) is the subject of a bo na fide investigation or proceeding with the Office of Inspector General, U.S. Departme nt of Health and Human Services, or another Governmental Authority, with respect to the marketing or commercialization of pharmaceutical products or ( D ) is engaged in significant litigation or other significant legal dispute with [COMPANY] or any of its Affiliates, as evidenced by written [ * ] = Certain confidential information contained in this document, marked by brackets, has been omit ted and filed separately with the Securities and Exchange C ommission pursuant to Rule 24b-2 of the Securities Act of 1934, as amended