definiens: means the efforts required in order to carry out a task in a diligent andsustained manner without undue interruption, pause or delay ; which level is at least commensurate with the level of effortsthat a biopharmaceutical company would devote to a product of similar potential and having similar commercial andscientific advantages and disadvantages resulting from the company ’s own research efforts ( i.e., explicitly ignoring theroyalty, milestone and all other payments due [COMPANY] under this Agreement ), taking into account its safety and efficacy, thecompetitiveness of alternative products, its proprietary position, pricing, reimbursement and other market - specific factors, andall other relevant factors . Commercially Reasonable Efforts requires ( without limitation ) that the Party exerting such efforts(i ) promptly assign responsibility for its obligations to specific employee(s ) who are held accountable for progress andmonitor such progress, on an ongoing basis, ( ii ) set and continue to seek to achieve specific and meaningful objectives forcarrying out such obligations, and ( iii ) make and implement decisions and allocate resources designed to advance progresswith respect to such objectives, in each case in a commercially reasonable manner