definiens: means compounds that act on, whether by modulation, stimulation, inhibition, or otherwise : 1.5.1 . the HCV [ genome and encoded proteins ] with respect to which Licensed Processes were employed at any time during the course of the research, development or commercialization of such compounds ; or 1.5.2 . [ a molecule of which any functional or catalytically active portion of the HCV genome and encoded proteins is a component part ], with respect to which Licensed Processes were employed at any time during the course of the research, development or commercialization of such compounds ; or 1.5.3 . HCV which [ are anti - HCV therapeutics and which are ] compounds ( a ) [ derived from, synthesized using, based on data from, or reasonably suggested by ] compounds defined by 1.5.1 or 1.5.2 above [ irrespective of whether ] Licensed Processes were utilized at any time during the course of the research, development or commercialization of such compounds ; [ and ] ( b ) [ whose research or development substantially or necessarily depends or depended upon ] activity that would infringe the [COMPANY] Patent Rights but for the rights granted hereunder