definiens: sha ll mean the actual out - of - pocket costs incurred, paid or borne by TAKE DA to manufacture, quality check and supply the Compound to PENINSULA . It is u nderstood that TAKEDA may elect to entrust the manufacture, quality check and /or supply of the Compound to a Third Party Manufacturer(s ) and in such event, al l the reasonable consideration for such entrustment to be paid by TA KEDA to such Third Party Manufacturer(s ) for the manufacture of the Compound supplied to PENINSULA shall be included in the Compound Manufacturing Cost . may include the actual purchase price of raw materi als, insurance payments, and any payment to third party(ies ) by TAKEDA to obtain a license under such third party 's patent or other intellectual property right s without which license the manufacture of the Compound would constitute an inf ringement of such patents or other intellectual property rights, if any, provide d that any such consideration is commercially reasonable