definiens: means a separate and distinct disease or medical condition in humans for which a Product that is in Clinical Trials isintended to treat, prevent and/or diagnose, or for which a Product has received Marketing Authorization as indicated on the approvedlabeling for such Product, as applicable . For clarity, a single Indication shall include the primary disease and variants or subdivisions orsubclassifications within such primary disease . For example, for purposes of the Agreement, [ * * * ] is a single Indication ; treatment ofmild, moderate or severe disease shall be treated as subclassifications within the single Indication of [ * * * ] Treatment, modulation and / orprophylaxis of the same disease [ * * * ] shall be treated as the same Indication . Treatment as monotherapy or treatment in combinationwith another product shall all be treated as the same Indication . Treatment, modulation and/or prophylaxis of the same disease [ * * * ] shall be treated as the same Indication . However, treatment, modulation and/or prophylaxis of any other type of disease ; [ * * * ], shall bedeemed a different Indication from treatment, modulation and/or prophylaxis of [ * * * ]