definiens: means Know - How as and to the extent Controlled by [COMPANY] or its Affiliates as of theEffective Date or at any time during the Term which relates to the Compound or a Product or to the Manufacture, use, sale, Development or Commercialization of the Compound or a Product . For the purposes hereof, [COMPANY] Know - How does notinclude Wyeth Collaboration Know - How, Wyeth Collaboration Joint Know - How, Ono Collaboration Know - How, OnoCollaboration Joint Know - How, [COMPANY] Collaboration Know - How, [COMPANY] ’s interest in Joint Know - How, or Know - HowControlled by a Third Party that becomes an Affiliate of [COMPANY] pursuant to a transaction or series of related transactions asa result of which such Third Party is able to elect a majority of the members of the board of 18directors of [COMPANY] ( or its successor company ) or any of its Controlling Affiliates ( a ) to theextent such Controlling Third Party ’s Know - How was Controlled by such Controlling Third Party ( and not by [COMPANY] ) priorto the completion of such transaction or series of related transactions