definiens: means any and all technical, scientific, regulato ry, clinical, medical, marketing, sales, financial and business informatio n and data, know - how, formulations, trade secrets, techniques, processes, ideas, concepts, designs, original works of authorship, enhancements, derivative works, ada ptations, discoveries and unpatented inventions developed, co nceived, reduced to practice, originated, prepared, learned, generated, obtained or made by or on behalf of a Pa rty or its Affiliates necessary for the manufacture or supply of either or both of GT4P and Ammonul HE, including ( a ) any and all documentation, Drug Master Files ( individually a and collectively ), protocols, manufacturing processes, starting ma terials, purification technologies and specifications for ei ther or both of such Development Product and that a re owned by Ucyclyd prior to the Effective Date or are devel oped, conceived, reduced to practice, originated, p repared, learned, generated, obtained or made by or on behal f of a Party or its Affiliates on and after the Eff ective Date and relating to the Products or arising out of the Agreement ; ( b ) any and all Improvements relating to any of the foregoing and necessary or reasonably useful for th e manufacture or supply of either or both of GT4P a nd Ammonul HE ; and ( c ) any and all intellectual proper ty rights in or to any of the foregoing . Notwithsta nding the foregoing, Manufacturing Know - How does not include any method of treatment, packaging, drug delivery, composition, formulation or dosage unit of a Develo pment Product, but does include any processes for manufacturing or supplying the method of treatment, packaging, drug delivery, composition, formulation or dosage unit of a Development Product . For clarity, intellectual property that Hyperion demonstrates wa s independently developed or acquired by or on behalf of Hyperion after the Closing shall not be include d as Manufacturing Know - How