definiens: shall mean a commercially reasonable level of efforts, commensurate with ( but in no event required to be greater than ) that level of efforts and resources eommonly dedieated in the research - based pharmaceutical industry by similarly situated companies to development and commercialization, as the case may be, of an internally developed product of similar commereial potential, at a similar stage in its lifecycle, and having similar commercial advantages and disadvantages, taking into aceount other relevant commercial, technical and scientific factors that are reasonably and eustomarily considered in the industry when planning, implementing, or making decisions regarding development and commercialization activities, except as provided below . shall be determined Iwithout ~egard to any activities, resources or opportunities with respect to the development andlor commercialization . of Direct Rho Kinase Inhibitors ( other than Products ) within the applicable lfields ( i.e., [COMPANY] Licensed Fields with respect to [COMPANY] or Asahi Licensed Indications ! with respect to Asahi, as the case may be )