definiens: shall mean receptor targets ( other than the Licensed Targets and Test Targets designatedby [COMPANY] as of the Effective Date ) which meet one of the following criteria : ( a ) the receptor target has been selectedby a Third Party, alone or in conjunction with ACADIA, as a licensed target for research and development pursuant toa written agreement between ACADIA and such Third Party prior to receipt by ACADIA of notice of selection byAllergan of such receptor target as a Test Target or a Program Target and such Third Party has entered into a bonafide collaboration and/or license agreement with ACADIA involving payments to ACADIA and diligence obligations bysuch Third Party ; ( b ) the receptor target has been selected by ACADIA as a receptor target for development byACADIA as part of an ACADIA internal research program prior to receipt by ACADIA of notice of selection by Allerganof such receptor target as a Test Target or a Program Target so long as such ACADIA internal development programis commercially reasonable in light of the potential product opportunities with respect to such target ( and ACADIAcontinues to expend resources on the diligent pursuit of compounds / products active against such target ), and in lightof resources then reasonably available to ACADIA ; ( c ) the receptor target has become, prior to receipt by ACADIA ofnotice of selection by [COMPANY] of such receptor target as a Test Target or a Program Target, the subject of activenegotiations between ACADIA and a Third Party with the objective of entering into an agreement as described inclause ( a ) above or ACADIA is spending substantial funds in an effort to enter into such negotiations with a ThirdParty ; or ( d ) the receptor target was already being considered by ACADIA, prior to receipt by ACADIA of notice ofselection by [COMPANY] of such receptor target as a Test Target or a Program Target, for an internal ACADIA researchprogram as evidenced by expenditure of substantial resources and commercially reasonable efforts by ACADIA inlight of the potential product opportunities with respect to such target