definiens: means any human gene ( other than an Excluded Targ et ) the expression or activity of which is demonstrated to, as its primary effect, treat, p revent or otherwise have a disease - modifying effect, on any neurological or psychiatric disease or disorder . Fo r clarity : ( a ) a gene includes protein coding regio ns as well as introns, promoters and termination regions ; and ( b ) a disease or disorder that primarily affects cells other than neurons, glia or myocytes, or a system other than t he central or peripheral nervous system, shall not be considered a neurological or psychiatric disease or disorder e ven if such disease or disorder causes neurological symptoms, and any gene that is associated with oncology, immu nology ( including all HLA genes ), metabolic disease, hematology or infectious disease can not be a Target . For clarity, the indications included within the Therapeutic Field and the Diagnostic Field shall not be limited by the fact that, in order for a human gene to con stitute a Target, the expression or activity of such 18 [ * ] = Certain confidential information contained in this document, marked by brackets, has been omitte d because it is both ( i ) not material and ( ii ) would be compe titively harmful if publicly disclosed