definiens: means Out - of - Pocket Costs and Commercial FTE Cost s reasonably necessary and identifiable to the Product incurred with respect to : medical and scientific information and response to external inquiries or complaints ; pharm acovigilance, investigator initiated research if no t covered in the U.S. Development Plan, medical education, Healt h Economics and Outcomes Research ( HECOR, HEMAR ), speaker programs, advisory boards, educational gran ts and fellowships, drug safety, local country gove rnment affairs, generating health economics and outcomes r esearch data from patient reported outcomes, prospe ctive observational studies and retrospective observation al studies, and economic models and reimbursement d ossiers ; and field based medical science liaisons, medical a ffairs clinical trial management, medical doctors i n field ( separate from medical science liaisons ), publicati ons, medical communications and field medical educa tion