definiens: means the grant from [ * * * ], and associated grant terms and conditions, dated [ * * * ] ; has the meaning set out in Clause 2.2.8 ; means any product or therapy which, were it not for the licence to iCAR Patent Rightsgranted hereunder, would otherwise infringe the iCAR Patent Rights in the relevant country of sale ; means the program of research defined in Schedule 1 under the title iCAR Program asconducted prior to the Amendment Date ; means excluding Manufacturing Know - How, ( i ) those patent applications listed inSchedule 2 under the title iCAR Patents and all Patent Rights derived therefrom ( ) ; ( ii)the Know - How described in Schedule 2 under the title iCAR Know - How ; and ( iii ) the materials listed inSchedule 2 under the title iCAR Materials together with all IP in the same ; means ( a ) any improvement, enhancement, development or advancement ( together with allIntellectual Property in the same ) over any of the Original Program IP in each case as created, generated ordeveloped by MP ( in the course of his activities or role at or for UCL or UCLB ) and/or the MP Laboratory, andwhich, if used, deployed or incorporated in the Exploitation of any product, process or service would result insuch product, process or service being within the scope of or otherwise dependent upon ( that is, in each case, in the absence of any licence, would otherwise infringe ) any one or more claims of any of the Original LicensedPatents ; and ( b ) any CAR developed or generated by MP ( in the course of his activities or role at or for UCL orUCLB ) or the MP Laboratory that targets any of GD2, BCMA, TRBC1, TRBC2, the CD19 Antigen and/or [ * * * ] ( other than a [ * * * ] Field Product ) ; CONFIDENTIAL TREATMENT HAS BEEN REQUESTED FOR PORTIONS OF THIS EXHIBIT . THE COPY FILEDHEREWITH OMITS THE INFORMATION SUBJECT TO A CONFIDENTIALITY REQUEST . OMISSIONS AREDESIGNATED [ * * * ] . A COMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED SEPARATELY WITH THESECURITIES AND EXCHANGE COMMISSION