definiens: means all scientific and technical information, data, and Know - How known to and Controlled by Five Prime as of the Effective Date or during the Term ( includingFive Prime ’s interest in any Collaboration Know - How jointly owned with [COMPANY] ) that is necessary or reasonablyuseful for the development of a Five Prime Pipeline Asset in combination with a Licensed Antibody or a LicensedProduct ( other than any Active Ingredients that are not Licensed Antibodies ) pursuant to the Development Plan, but excluding ( a ) all Five Prime Licensed Know - How, ( b ) all information, data or Know - How within the Five PrimePlatform Technology, ( c ) all Know - How that is Unilateral Intellectual Property, except to the extent that [COMPANY] hasreimbursed Five Prime for the Development Expenses for such Five Prime Unilateral Studies pursuant to Section4.4 and ( d ) all Know - How that comes into Five Prime ’s Control as a result of a Change of Control of Five Prime