definiens: shall mean ex vivo gene therapy for human disorders limited to adrenoleukodystophy ( ALD ) ( including but not limited to AMN, CCALD, and all other variants of this disease caused by genetic mutations ), beta hemoglobinopathies ( including but not limited to beta­thalassemia and sickle cell anemia ), ( hemophilia, lysosomal storage disorders ( LSDs, including Gaucher disease, Fabry disease, Pompe disease or GAA deficiency, and mucopolysaccharidosis I, II and VI ), HIV / AIDS, eye diseases ( including but not limited to AMD and Stargardt disease ), and Parkinson 's Disease ;) for ( Parkinson 's Disease and eye diseases ( including but not limited to AMD and Stargardt disease » ) the includes in vivo as well as ex vivo gene therapy . ( Licensee and/or Affiliates shall have the right to request Institut Pasteur to expand the definition of the to include additional clinical areas . To expand the Field, Licensee and/or Affiliates shall provide written notification to Institut Pasteur that it or its Affiliates has initiated a program in such area(s ) . If Institut Pasteur does not object, the Parties shall execute a formal amendment to the Agreement within sixty ( 60 ) days thereafter . No further copsideration sha, pasteur for the expanded Fie'd For clar;t ) ' the Field excludes any other fields and specifically prophylactic and therapeutic human and veterinary vaccination against all kind of pathogens . ) 2.2 . The article 2.1 of the Agreement is modified as follow, as from the effective date of this Amendment n ° I : " 2.1 . Institut Pasteur hereby grants to Licensee, its Affiliates, that Licensee, its Affiliates accept at their own risk, a license under the Patents in the Field and in the Territory for research and development, and to manufacture, have manufactured, make, have made, use, have used, sell, have sold, offer for sale, have offered for sale, import or have imported the Products, to the exclusion of any other rights, the said license being : -exclusive for Products containing human ( HIV - l and HIV-2 ) lentivirus vector ; -nonexclusive for Products containing non - human lentivirus vector