definiens: means all Patents Controlled by Isis on or prior to the [ * * * ] anniversary of theSecond Restatement Date that ( a ) claim ( x ) an oligomeric compound that hybridizes to and modulates anAlnylam Exclusive Target or ( y ) a method of using such oligomeric compound in the Field ; or ( b ) are ChemistryPatents or Motif and Mechanism Patents other than Patents described in clause ( a ) above ; provided, howeverthat ( A ) for any such Patents that are acquired, licensed or invented after the Restatement Date that includefinancial or CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT WERE OMITTED AND REPLACED WITH . ACOMPLETE VERSION OF THIS EXHIBIT HAS BEEN FILED SEPARATELY WITH THE SECRETARY OF THESECURITIES AND EXCHANGE COMMISSION PURSUANT TO AN APPLICATION REQUESTING CONFIDENTIALTREATMENT UNDER RULE 24b-2 OF THE SECURITIES EXCHANGE ACT OF 1934