definiens: means any Know - How, invention or discovery ( and all Intellectual Property claiming orcovering such invention or discovery ) conceived, discovered, or made by or on behalf of Naia, its Aﬃliates, or its or theiragents, Sublicensees, or contractors ( other than Amunix ), alone or jointly with any Third Party, in the course of theResearch Program or otherwise in connection with this Agreement, whether patentable or not, that ( i ) are directly related toGLP-2 receptor agonists and/or analogs of GLP-2 discovered or invented by or on behalf of Naia, any Aﬃliate thereof, orany Sublicensee, alone or jointly with any Third Party, and any Intellectual Property claiming or Covering such invention ordiscovery, ( ii ) are methods or uses for the treatmentof indications or treatment regimens for Licensed Products or XTEN Sequences, or ( iii ) comprise, or are related to, otheractive pharmaceutical ingredients or therapeutic moieties . For the avoidance of doubt, ( a ) excludes ( I)any and all XTEN Sequences and derivative, modiﬁed, or truncated amino acid sequence compositions of XTEN Sequencesconceived, discovered, or made in connection with this Agreement, or as a result of using Amunix ’s Conﬁdential Information, by either Party ( or any Aﬃliate thereof ), solely or jointly with the other Party ( or any Aﬃliate thereof ), ( II ) any XTENModiﬁcations conceived, discovered, or made that were enabled as a result of the exercise of rights granted by Amunixunder this Agreement, or as a result of using Amunix ’s Conﬁdential Information, by either Party ( or any Aﬃliate thereof),solely or jointly with the other Party ( or any Aﬃliate thereof ), or ( III ) methods of making such amino acid sequencecompositions in ( I ) or ( II ) conceived, discovered, or made in connection with this Agreement, or as a result of using Amunix’sConﬁdential Information, by either Party or any Aﬃliate thereof, whether or not included in a composition of any modiﬁed orunmodiﬁed GLP-2 and ( b ) such XTEN Sequences and sequence variants thereof described in ( a ) shall be considered either or, as appropriate