definiens: shall mean Technology related to ( A. ) Cleavase Enzymes or Invader Reacti.ons, ( B ) methods or compositions ( 1 ) for prol : ie design fOF Invader Reactions or assays that use Cleavase Enzymes, which may include target selection, or ( 2 ) for enhanced ease of use or sample preparation for assays that use or incorporate Cleavase Enzyme or perfoml an ): nvader Reaction ; ( e ) the use ( including methods of use and new applications ) of manufacture of any Cleavase Enzyme, Invader Reaction, or such assays, methods, or compositions ; m ( D ) provements, derivatives or otbe . modificatious to any Cleavase Enz e Invader Reaction or = u ... a, s::::a.),s methods com ositions, manufacture or use