definiens: ) to the Supply Agreement, asdefined below, is made and entered into as of July 1, 2015 ( the ) by and betweenTeva API, Inc. ( formerly known as Plantex USA Inc. ), a New Jersey corporation with offices at400 Chestnut Ridge Road, Woodcliff Lake, NJ 07670 ( ) and The Medicines Company, aDelaware corporation with offices at 8 Sylvan Way, Parsippany, NJ 07054 ( ) . TEVA andMDCO are sometimes together referred to herein as the and separately as a WHEREAS, TEVA and MDCO entered into a certain Supply Agreement datedSeptember 30, 2011 as amended on February 13, 2012, ( collectively the ) ; andWHEREAS, the Parties desire to enter into this Second Amendment to makecertain modifications to the terms and conditions of the Supply Agreement;NOW, THEREFORE, in consideration of the foregoing premises and the mutualagreements set forth below, and other good and valuable consideration the receipt andsufficiency of which are hereby acknowledged, the Parties hereby agree as follows:1