definiens: means all Know -How excluding CFE Manufacturing Know -How ( a ) that is Controlled by Sutro or any Affiliate of Sutro as of the Effective Date or at any time duri ng the Term ( including pursuant to Section 8.3 ( a ) ), and a ny Know - How that is invented, conceived, or developed ( A ) by or on behalf of either or both Par ties, or its or their Affiliates or Third Parties a cting on its or their behalf, in each case in the course of conducting its or their activities under this Agreement, or ( B ) by or on behalf of any Sublicense e in the course of conducting activities under a permitted sublicense hereunder, and ( b ) to the extent relating to or consisting of ( i ) a Sutro Payload, ( ii ) a Sutro Linker, ( iii ) Sutro ’s proprietary Cell Free Extract express ion technology to the extent related to the making, using, selling or offering for sale of a Product, ( iv ) the combination of a Sutro Payload with a Linker th at is in the public domain ( v ) the c ombination of a Payload that is in the public domai n with a Sutro Linker, ( vi ) the conjugation of a Sutro Payload or a Payloa d that is in the public domain to an Antibody using a Sutro Linker ( including the modification of an Antibody to facilitate such conjugation and the identity or identification of preferred sites on an Antibody for such conjugation and excluding the specific conjugation to a [COMPANY] Antibody and also e xcluding the identity or identification of preferre d sites on a [COMPANY] Antibody for such conjugation )