definiens: means any invention comprising the composition of matter of, process of making, or methods of using ( a ) any [ * ] or [ * ] provided, directly or indirectly, by [COMPANY] to IE or [COMPANY] or other [ * ] covered by a Valid Claim, ( b ) any gene, portion of any gene, protein, promoter, signal peptide, terminator, or integration site obtained from the [ * ] or [ * ] described insubsection ( a ) above, ( c ) any progeny, derivative, or modification of ( a ) or ( b ), or ( d ) any mixture of proteins in specified ratiosproduced using the [ * ] or [ * ] described in subsection ( a ), or a derivative or modification thereof . For purposes of clarification, notwithstanding anything to the contrary, does not include any invention that is ( i ) an enhancement, modification, or improvement of, or to, any [ * ], including without limitation any such [ * ] contained within the [ * ] or [ * ] described in subsection ( a ) above and/or covered by a Valid Claim except where the invention improves the [ * ] generally(which shall be included within Improvements ), or ( ii ) Shuffling Technology