definiens: means the parties to this Agreement, their respective successors and permitted assigns, and means either one of them ; means the ‘ Research and Collaboration Agreement ’ between [COMPANY] and [COMPANY] of 11 July2014, as amended ; means the letter of 4 August 2014 between [COMPANY] and [COMPANY] regarding ‘ Patent Family titled‘HBV Treatment ’ ( PCT / CN2011/081386 ) ’ ; 1 means any claim in ( i ) any issued and unexpired HBV Patent that has not been held unenforceableor invalid by a court or other governmental agency of competent jurisdiction in an unappealed or unappealabledecision, and which has not been disclaimed or admitted to be invalid or unenforceable through reissue, reexamination, opposition, interference or otherwise, or ( ii ) any composition of matter, article of manufacture, ormethod of use claim contained in a HBV Patent application that has been pending for no more than seven(7 ) years from the first priority date claimed in such patent application