definiens: shall meanEny substance that binds to VLA-4 ] 1.39 shall mean any information, know - how or materials : ( i ) owned or controlled by TBC and/or any of its Affiliates as of the Effective Date relating to VLA-4 ; ( ii ) discovered or developed by or on behalf of TBC and/or any of its Affiliates during the term of this Agreement in performance of the Research Program ; or ( iii ) owned or c ~ ntrolled by TBC and/or any of its Affiliates relating to the research, development, manufacture, marketing, use or sale of Licensed Compound(s ) and/or Licensed Product(s ), and in each case which are not in the - 7 -::ODMA\PCDOCS\Docs\339538\1 CONFIDENTIAL TREATMENT REQUESTED public domain . VLA-4 Know - How shall include, without limitation, all applications, registrations, licenses, authorizations, approvals and correspondence relating to Licensed Compound(s ) and/or Licensed Product(s ) submitted by TBC to regulatory authorities as well as all biological, chemical, pharmacological, toxicological, pharmaceutical, physical and analytical, clinical, safety, manufacturing and quality control data and information related thereto