definiens: means license initiation fees and other up - front payments made to AMICUS in connectionwith a sublicense or other similar arrangement ; shall mean any Licensed Product : ( i ) for the treatment of Conformational Diseases, including, butnot limited to, Licensed Products used as monotherapy for Conformational Diseases and Licensed Products used incombination therapy with exogenously administered therapeutic proteins for Conformational Diseases ; ( ii ) discovered anddeveloped by AMICUS for use in combination therapy with exogenously administered therapeutic proteins or geneconstructs for the treatment of diseases other than Conformational Diseases ; ( iii ) addressing the production, formulation, or storage of therapeutic proteins manufactured by third parties for the treatment of Conformational Diseases and(iv ) discovered and developed by AMICUS to address the production, formulation, or storage of therapeutic proteinsmanufactured by third parties for the treatment of diseases other than Conformational Diseases