definiens: means, with respect to any particula r Product in any particular Jurisdiction in the Territory, the period commencing with the First Com mercial Sale of such Product in such Jurisdiction a nd continuing until the latest of ( a ) expiration or te rmination of all regulatory approvals for the Produ ct in any Jurisdiction, including any renewal thereof, ( b ) th e earliest date on which there are no Valid Claims of Palatin Patent Rights Covering such Product in such Jurisdi ction, ( c ) the last day of the Regulatory Exclusivi ty Period for such Product in such Jurisdiction and ( d ) the tenth ( 10th ) anniversary of the First Commercial Sale of the Product in such Jurisdiction . For the avoidance of doubt, t he Royalty Term for a given Product in a given Juri sdiction in the Territory ( i ) will not begin until the First Co mmercial Sale of such Product in such Jurisdiction and ( ii ) if not previously expired, will expire immediately upon ex piration or termination of this Agreement