definiens: means any of the following decisions requiring the unanimous approval of all members of the JSC, the JDC and/or theJMC, as the case may be : ( a ) any determination as to whether a milestone has been achieved under Section 6.3.1 of this Agreement for which a milestonepayment is payable ; ( b ) any decision that relates to the Co - Development or Co - Promotion of a Co - Developed Product ( including without limitation anydecision with respect to the manufacture of such Co - Developed Product within the Co - Development Territory ) in the Co - Development Territory ; ( c ) anydecision that results, or would reasonably be expected to result, in an increase in the amount of Co - Development Costs payable by a Party pursuant toSection 5.1 of more than [ * * * ] [ * * * ] percent ( [ * * * ] % ) in any Calendar Year as compared to the amount of Co - Development Costs forecasted in the then currentCo - Development Plan for that Calendar Year for any reason ( including, without limitation, as a result of a change in the number of patients, number of sites, duration of the study or the number of studies ) ; ( d ) the initial allocation of Detailing responsibilities between the Parties with respect to a Co - DevelopedProduct ; ( e ) any disputed matter which, in accordance with the terms of this Agreement, is referred to the JSC by the JDC, the JFC or the JMC ; and ( f ) withrespect to each Licensed Product that is a Co - Developed Product, the determination of the indication(s ) for which such Co - Developed Product shall be usedin the Co - Development Territory