definiens: means any and all Patent Rights which during the term of this Agreement are Controlled byAVEO, including, but not limited to, those listed on Subpart A of Schedule 1.7, which schedule shall be updated byAVEO reasonably promptly upon the filing of such Patent Rights or otherwise at the request of MERCK, and which:(i ) claim the composition of -2- matter of a Collaboration Compound and/or Product or the use of a Collaboration Compound and/or Product Directed toa Non - MAP Collaboration Target or Discovery Target ; ( ii ) claim AVEO Know - How ; ( iii ) claim AVEO Information andInventions, or ( iv ) are necessary or useful to MERCK in the research of the Non - MAP Collaboration Targets or the MAPCollaboration Targets, and/or the research, development, manufacture, marketing, use or sale of CollaborationCompound or Product in the Territory in the Field, but excluding all Patent Rights which are necessary or useful inconnection with or that claim or cover the Collaboration Models or any other method, material, tool or technologyconceived or used by or on behalf of AVEO for the discovery of any target other than the Non - MAP CollaborationTargets or the MAP Collaboration Targets