definiens: means, with respect to a particular time period, the total amounts invoiced by [COMPANY], its Affiliates andtheir respective sublicensees for sales of Products made during such time period to unaffiliated Third Parties, less thefollowing deductions in each case to the extent reasonable and customary and actually allowed or incurred with respect tosuch sales:(a ) discounts, including cash and quantity discounts ( including early payment discounts ), charge - back payments, and rebates actually granted or administrative fees actually paid to trade customers, patients ( including those in the form of acoupon or voucher ), managed health care organizations, pharmaceutical benefit managers, group purchasing organizations, federal, state, or local government and the agencies, purchasers and reimbursers of managed health organizations, pharmaceutical benefit managers, group purchasing organizations, or federal, state or local government ; [ * ] = INDICATES THAT CERTAIN INFORMATION CONTAINED HEREIN HAS BEEN OMITTED AND FILEDSEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 24B-2 OF THESECURITIES ACT OF 1934, AS AMENDED . CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITHRESPECT TO THE OMITTED PORTION