definiens: means ( a ) Know- How that Ironwood or any of its Affiliates Control as of the Effective Date, including Know - How that h as arisen or arises under the Existing Agreements t o the extent Controlled by Ironwood or its Affiliates, or that comes into the Control of Ironwood or its Affiliates during the Term ( other than Joint Know - H ow and Development Data ) to the extent necessary or useful to Develop, Manufacture or Commercialize the Licensed Compound or Product in the Territory, including without limitation any method of making t he Licensed Compound or Product, any composition or formulation of the Licensed Compound or Product, or any method of using or administering the Licensed Compound or Product, except to the extent that any such Know - How relates solely to any active ingredient in a Product other than the Licensed Com pound, ( b ) all clinical, pharmacology, toxicology a nd other biological data with respect to the Licensed Compound or a Product to the extent Controlled by Ironwood or any of its Affiliates during the Term a nd necessary or useful to Develop, Manufacture or Commercialize the Licensed Compound or Product in t he Territory, in each case other than Development Data and ( c ) Collaboration Know - How ( other than Joi nt Know - How and Development Data ) that is invented, conceived or developed by one or more of the following : employees of Ironwood or its Affiliates, or Third Parties acting on behalf of Ir onwood or its Affiliates . Ironwood Know - How include s Reference Standards Know - How