definiens: means the treatment and/or prophylaxis of a disease or condition, by regional, local, systemic orother delivery, localization and/or administration of Cells . The term specifically excludes using ( a ) any ofthe Cells as reagents ; ( b ) any of the Cells for diagnostic applications or assays ; and ( c ) any of the Cells for drug and drugtarget validation screening . The term specifically includes ( x ) delivery, localization and/or administrationof a protein, peptide, gene, polynucleotide, small molecule or other active pharmaceutical ingredient ( or any combinationof the foregoing ) at or near the time of delivery, localization and/or administration of Cells ; ( y ) delivery, localizationand / or administration of one or more fractions and/or subsets of Cells ; and ( z ) delivery, localization and/or administrationof one or more other cell types at or near the time of delivery, localization or administration of Cells