definiens: means, the gross amount billed or invoiced on sal es of Licensed Products by Company, its Affiliates and Sublicensees, less dedu ctions actually taken or applied, as determined in accordance with, and as permitted by, U.S. generally accepted accounting principles as consistently applied acros s Company ’s, its Affiliates ’ and Sublicensees ’ ( as ap plicable ) pharmaceutical products generally, includ ing the following : ( a ) customary trade quantity, or cash discounts to non - affiliated brokers or agents to the extent actu ally allowed and taken ; ( b ) amounts repaid or credited by reason of reje ction or return or because of chargebacks, rebates or retroactive price reductions ; ( c ) to the extent separately stated on purchase ord ers, invoices, or other documents of sale, any taxe s or other governmental charges levied on the production, sale, transportation, delivery, or use of a Licensed Pr oduct which is paid by or on behalf of Company, its Affiliates or Sublicensees ; and ( d ) outbound transportation costs prepaid or al lowed and costs of insurance in transit