definiens: means, with respect to any Product, efforts of a Person to carry out its obligations in adiligent manner using such effort and employing such resources normally used by such Person in the exercise of itsreasonable business discretion relating to the research, development or commercialization of a product, that is ofsimilar market potential at a similar stage in its development or product life, taking into account issues of marketexclusivity ( including patent coverage, regulatory and other exclusivity ), safety and efficacy, product profile ( includingtolerability and convenience ), the competitiveness of alternate products in the marketplace or under development, thelaunch or sales of one or more generic or biosimilar products, actual or likely pricing / reimbursement for the product, the likely timing of the product ’s entry into the market, the likelihood of regulatory approval of the product andapplicable labeling, and the profitability of the applicable product, and other relevant factors, including technical, commercial, legal, scientific, and/or medical factors, based on conditions then prevailing