definiens: shall mean all patents, patent applications, and invention disclosures ( all as listed on Exhibit 1.28 ) and all information, materials and other subject matter made or controlled by Sunesis, and improvements thereof, relating to ( i ) utilization of mutated Primary Targets and/or Secondary Targets in screening, ( ii ) the use of novel protein engineering techniques and their application in drug discovery, ( iii ) target - directed fragment discovery and maturation to produce drug leads, including monophore libraries for such purposes, ( iv ) covalent tethering and techniques related thereto ( e.g. NMR, X - ray, mass spec . AUC, Biacore ) and its use to discover fragments and test binding hypotheses of fragments and leads, or ( v ) dynamic and other combinatorial chemistries related to proteins, the subject of which is an invention made : ( a ) by Sunesis prior to the Effective Date or in the course of performing the Research Program ; or ( b ) by employees of [COMPANY] or its Affiliates during the Exclusivity Period in the course of activities directed to the discovery, research or development Biogen.$unesis Collabor.di on 7 I = Confidential Treatment Requested of compounds for use in the Field ; provided, in the case of ( b ) that such item was made using or derived from Sunesis Core Technology . Sunesis Core Technology shall also include any divisions, continuations, continuations - in - part, reissues, reexaminations, extensions or other governmental actions which extend any of the patent applications or patents in ( a ) or ( b ) above, and any substitutions, confirmations, registrations, revalidations or foreign counterparts of any of the foregoing