definiens: shall mean any know - how, technical and other information, documents, studies, results and data developed by Columbia prior to the Effective Date by Angela Christiano, Ph.D., Raphael Clynes, M.D., Ph.D. ( the ), or an individual under the direction ofInvestigator(s ) and provided to or received by Company, which know - how, technical and otherinformation, documents, studies, results and data are necessary or useful for the discovery, development, manufacture, use, sale, offering for sale, importation, exportation, distribution, rental orlease of a Licensed Product, including, without limitation, any know - how, technical and otherinformation, documents, studies, results and data that is ( i ) disclosed in any Patent Rights, ( ii ) relatesto the use of Janus kinase ( JAK ) inhibitors for alopecia areata, androgenetic alopecia, and/or otherinflammatory skin diseases, or ( iii ) any reports or disclosures concerning research or inventionsprovided or disclosed to, or otherwise received by, Company