definiens: shall mean using, in the relevant Major Countries, an equivalent degree of effort as GTX, its Affiliate or a GTX Unaffiliated Sublicensee would use to promote, market, distribute and sell a product of its own that is of comparable market potential in such Major Country during the same time period ( as determined by consideration of, without limitation, potential market, patent protection, and availability of competitive products ), including but not limited to, engaging in the following activities ( subject to any applicable U.S. FDA restrictions or other applicable legal restrictions ): ( a ) Using reasonable diligence to establish and maintain good business relationships with hospitals, health systems, doctors and other medical professionals in accordance with standard and customary practices in such Major Country ; ( b ) Using commercially reasonable efforts to establish and maintain an adequate capacity of sales personnel consisting of reasonably qualified personnel who have been certified, as trained by GTX, its Affiliate or a GTX Unaffiliated Sublicensee, to promote and market the Product for use in the Prostate Cancer Field in such Major Country, and to provide such sales force with adequate sales and promotional materials for the Product ; ( c ) Promoting and detailing the Product for use in the Prostate Cancer Field throughout such Major Country, provided that GTX, its Affiliate or a GTX Unaffiliated Sublicensee may, in its discretion use relatively greater promotional and detailing efforts ( i ) in some Major Countries than it uses in other of such countries, and ( ii ) in some parts of each Major Country than in other parts thereof, consistent with its overall marketing plan ; and further provided, however, that the foregoing shall in no event be deemed to limit GTX 's its Affiliate or a GTX Unaffiliated Sublicensee overall obligations under the first paragraph of this Section 6.3.1