definiens: means the patent which is attached hereto as Appendix A, -6- 7 and any other valid U.S. and foreign pa tents relating thereto, including without limitation, all subst itutions, reissues, renewals, reexaminations, patents of addition, ex tensions, registrations, confirmations, and all pending patent a pplications, ( including provisional applications, continuations, divisionals and continuation - in - part ), which is owned o r CONTROLLED by TANABE or its AFFILIATES as of the EFFECTIVE DATE or during the term of this Agreement . The shall in clude but not be limited to patents directed to new uses of the com pounds claimed within the TANABE PATENT in the FIELD, and patents directed to manufacturing and formulation of the compounds claime d within the TANABE PATENT in the FIELD unless otherwise set forth he rein . Notwithstanding anything herein to the contrary, the shall expressly exclude any claims within patents direc ted to formulations of the RAPIDLY DISINTEGRATED TABLET whether ma de by or on behalf of TANABE or its AFFILIATES before or after the E FFECTIVE DATE