definiens: means Irofulven and/or any pharmaceutically - activ e formulations of Irofulven except Irofulven when bound directly or via a linker to al l of the following conjugates : an antibody, antibod y fragment, peptide, growth factor, receptor proteins, receptor binding entity, lipids, liposomal partic les, nanoparticles, PEG carriers, steroids, proteins, to xins, or another drug conjugate ( hereinafter ) or Irofulven Analogues whether or not bound directly or via a linker to a Conjugate . For clarity Compound does not include illudin bound dir ectly or via a linker to a Conjugate or acylfulvene bound directly or via a linker to a Conjugate, incl uding an illudin analog bound directly or via a lin ker to a Conjugate, or acylfulvene analog bound directly o r via a linker to a Conjugate