definiens: means any Know - How, invention or discovery ( and all Intellectual Propertyclaiming or covering such invention or discovery ) conceived, discovered, or made by or on behalf of Naia, its Aﬃliates, or itsor their agents, Sublicensees, or contractors ( other than Amunix ), alone or jointly with any Third Party, in the course of theResearch Program or otherwise in connection with this Agreement, whether patentable or not, that ( i ) are directly related toGLP-1 receptor agonists and/or analogs of GLP-1 discovered or invented by or on behalf of Naia, any Aﬃliate thereof, orany Sublicensee, alone or jointly with any Third Party, and any Intellectual Property claiming or Covering such invention ordiscovery, ( ii ) are methods or uses for the treatment of indications or treatment regimens for Licensed Products or XTENSequences, or ( iii ) comprise, or are related to, other active pharmaceutical ingredients or therapeutic moities . For theavoidance of doubt, ( a ) excludes ( I ) any and all XTEN Sequences and derivative, modiﬁed, ortruncated amino acid sequence compositions of XTEN Sequences conceived, discovered, or made in connection with thisAgreement, or as a result of using Amunix ’s Conﬁdential Information, by either Party ( or any Aﬃliate thereof ), solely or jointlywith the other Party ( or any Aﬃliate thereof ), ( II ) any XTEN Modiﬁcations conceived, discovered, or made that were enabledas a result of the exercise of rights granted by Amunix under this Agreement, or as a result of using Amunix ’s ConﬁdentialInformation, by either Party ( or any Aﬃliate thereof ), solely or jointly with the other Party ( or any Aﬃliate thereof ), or ( III)methods of making such amino acid sequence compositions in ( I ) or ( II ) conceived, discovered, or made in connection withthis Agreement, or as a result of using Amunix ’s Conﬁdential Information, by either Party or any Aﬃliate thereof, whether ornot included in a composition of any modiﬁed or unmodiﬁed GLP-1 and ( b ) such XTEN Sequences and sequence variantsthereof described in ( a ) shall be considered either or, asappropriate