definiens: means, with respect to any Licensed Product and a given country or jurisdiction for the purposes of determining royalties payable to Black Belt pursuant to Section 5.4.1(b ) ( Region -Specific Royalty Rates for Existing Licensed Products ) and Section 5.4.1(c ) ( Region -Specific Royalty Rates for Next Generation Licensed Products ), the gross amount invoiced by CASI or its Affiliates or Sublicensees ( excluding any Third Party Distributors ), including gross amounts invoiced to wholesalers and Third Party Distributors, to each Third Party receiving Licensed Product in arm ’s length transactions in such country or jurisdiction, less the following deductions from such total amounts that are actually incurred, allowed, accrued, or s pecifically allocated : ( a ) credits, price adjustments, or allowances for damaged products, and returns or rejections of such Licensed Product ; ( b ) trade, cash, and quantity discounts, allowances and credits ( other than price discounts granted at the time of invoicing that have already been included in the gross amount invoiced ) ; ( c ) chargeback payments and rebates ( or the equivalent thereof ), retroactive or otherwise, granted to group purchasing organizations, managed health care organizations or to federal, state / provincial, local, and other governments, including their agencies, or to trade customers ; ( d ) any invoiced freight, postage, shipping, insurance, and other transportation charges, as well as any fees for services provided by whol esalers and warehousing chains related to the distribution of such Licensed Product ; ( e ) sales, value -added ( to the extent not refundable in accordance with Law ), and excise taxes, tariffs and duties, and other taxes directly related to the sale ( but not including taxes assessed against the income derived from such sale ) ; ( f ) the portion of administrative fees paid during the relevant time period to group purchasing organizations, pharmaceutical benefit managers, or Medicare Prescription Drug Plans relating to such Licensed Product ; ( g ) any consideration actually paid or payable for any Delivery System related to a billed or invoiced sale of such Licensed Product, where for purposes of this Black Belt Net Sales definition, a me ans any delivery system designed to assist in the administration of such Licensed Product ; - 4 - ( h ) any reserves for uncollected amounts, including bad debt ; ( i ) that portion of the annual fee on prescription drug manufacturers imposed by the Patient Protection and Affordable Care Act, Pub . L. No . 111 -148 ( as amended ) and reasonably allocable to sales of the Licensed Products ; and ( j ) any other similar and customary deductions that are consistent with GAAP, but which may not be duplica tive of the deductions specified in ( a ) – ( i ) above