definiens: means a Compound that is reasonably determined by [COMPANY] ’ RMC in accordance with [COMPANY] ’ standard procedures for designating developm ent candidates [ * * * ] as ready to start IND - Enabling Toxicology Studies ; provided, however, that with respect to any Primarily Neuro Multi - In dication Target, such Compound will be reasonably selected by [COMPANY] ( giv ing good faith consideration to the input of [COMPANY] ’ representatives on the Neurology JRC ) as a Developm ent Candidate from the body of work [COMPANY] used to d etermine the applicable Compound [COMPANY] believes is ready to start IND - Enabling Toxicology Studies . The checklis t [COMPANY] uses as of the Effective Date when reviewing potent ial development candidates for approval is attached hereto as APPENDIX 2