definiens: means:(a ) in the case of the Mir-21 Fibrosis POC Program, ( i ) the treatment and/or prophylaxis of any or allIndications in Fibrosis and ( ii ) to the extent that Regulus Controls [ … * * * … ] the applicable Collaboration Target as [ … * * * … ] to the corresponding Licensed Compound in the treatment and/or prophylaxis of an Indication in Fibrosis(collectively, the ) ; or(b ) in the case of the Mir-21 Oncology POC Program or the Mir-221/222 Oncology POC Program, ( i ) thetreatment and/or prophylaxis of any or all Indications in Oncology and ( ii ) to the extent that Regulus Controls [ … * * * … ] the applicable Collaboration Target as [ … * * * … ] to the corresponding Licensed Compound in the treatment and / orprophylaxis of an Indication in Oncology ( collectively, the )