definiens: or means any effect or change that would be ( or couldreasonably be expected to be ) materially adverse to the business, assets, condition ( financial or otherwise ), operatingresults, operations, or business prospects of the Business taken as a whole ; provided, however, that in determiningwhether a Material Adverse Effect or Material Adverse Change has occurred, the following changes or effects shallnot be considered and shall be deemed not to constitute a Material Adverse Effect or Material Adverse Change:(i ) changes in the oncology industry generally ( including, but not limited to, the competitive or regulatory environmentaffecting injectable Paclitaxel in any market, the sale price of injectable Paclitaxel and the costs associated with themanufacture or sale of injectable Paclitaxel ) ; ( ii ) changes in economic conditions in the United States or globally or inthe financial markets in general ; ( iii ) changes of which Buyer has Knowledge that result from actions taken or to betaken in connection with the transactions contemplated by this Agreement ; ( iv ) changes in Law that apply generally tosimilarly situated persons ; ( v ) any change or effect to the extent constituting or involving only assets other thanAcquired Assets or only liabilities other than Assumed Liabilities ; and ( vi ) any change in or effect on the AcquiredAssets that is cured ( including by payment of money ) before the earlier of the Closing and the termination of thisAgreement pursuant to § 9