definiens: shall mean the fu lfilling of obligations diligently and in good - fait h, in each case, in a manner consistent with the efforts a party would be expected to devote to a product of similar market potential, profit potential, strateg ic value and potential for receiving all required r egulatory approvals required for marketing, sale and distribu tion, resulting from its own research efforts, base d on conditions then prevailing, taking into account, wi thout limitation, issues of safety and efficacy, pr oduct profile, intellectual property situation, regulator y environment and other relevant scientific and com mercial factors . Without limiting the foregoing, Commercial ly Reasonable Efforts in all cases shall require at least that ( i ) such party promptly assign responsibility for such obligations to specific employee(s ) who mo nitor progress ; ( ii ) such party set and seek to achieve s pecific and meaningful objectives for fulfilling su ch obligations ; and ( iii ) such party makes and impleme nts decisions and allocates resources designed to advance progress with respect to such obligations