definiens: means the volume weighted average of the closing prices of TGTX Common Stock on The NASDAQ Global Market ( or, if th e Common Stock of TGTX is not listed on the NASDAQ Global Market, the principal exchange or interdeale r quotation system on which the TGTX Common Stock i s listed ) for the ten ( 10 ) trading days prior to the Effective Date ; provided, however, that in the even t that TGTX effects a stock split, combination or stock dividen d at any time during such 10 trading days or subseq uent thereto and prior to the issuance of the Initial Shares, th e number of shares of TGTX Common Stock issuable sh all be appropriately adjusted to give effect to such actio n. Within five ( 5 ) business days of the Effective D ate, TGTX shall issue to Rhizen certificates representing the Initial Shares