definiens: shall mean any product in the form of a device, compound, kit or service useful for the diagnosis, prognosis, prediction or disease management of a Selected Disease which device, compound, kit or service contains a component which is ( a ) able to detect and/or quantify the presence or amount of ( i ) a Disease Gene that affects the pathogenesis of the Selected Disease, or ( ii ) a product of a Disease Gene that affects the pathogenesis of the Selected Disease, or ( iii ) another member of a Biological Pathway of which the Disease Gene is a member, or ( b ) is derived from Biological Materials, such component being conceived and reduced to practice as a result of a Research Program by a Party . its Affiliate or its Collab('r ~ t()r . at any time durin .. g a period commencins . on tl : te ~ffe ~ tive Date and ending : five ( 5 ) years after a first Candidate Gene Connrmation for the Selected Disease