definiens: means ( a ) the national, regional and internationa l patents and patent applications, including provisional patent applicat ions set forth on Schedule 1.58, ( b ) all patent applications Controlled by [COMPANY] or its Affiliate s during the Term that claim priority to any patent s or patent applications in clause ( a ), including divisi onals, continuations, continuations - in - part, conver ted provisionals, and continued prosecution application s, as well as any substitute applications with resp ect to any patent applications in clause ( a ), ( c ) any and all patents that have issued or in the future may i ssue from any of foregoing patent applications in clause ( a ) or clause ( b ), to the extent Controlled by Gen zyme or its Affiliates during the Term, including utilit y patents, utility models, petty patents and design patents and certificates of invention, and ( d ) any and all re - issues re - examinations renewals, revalidations, restorations or extensions ( including any supplemen tary protection certificates and the like ) of any o f the foregoing patents or patent applications in clause ( a ), clause ( b ), or clause ( c ) to the extent Contro lled by [COMPANY] or its Affiliates during the Term