definiens: shall mean the gross amount invoiced for any sale of a Lixivaptan Product by a Selling Person toa non - Affiliate of the Selling Person or to an Affiliate of the Selling Person if such Affiliate is not itself a Selling Person, less the sum of thefollowing deductions, in each case to the extent actually and reasonably allowed or incurred in connection with such sale of such LixivaptanProduct in accordance with GAAP:(A ) reasonable and customary trade, cash and quantity discounts off the invoiced price;(B ) all excise, sales and other consumption taxes and custom duties to the extent included in the invoice price;provided, however, that, with respect to excise tax payments pursuant to Section 9008 of the Patient Protection and Affordable Care Act of2010, any such deduction shall be limited to the proportionate share of such excise tax equal to the proportionate share that the aggregatesales of such Lixivaptan Product by such Selling Person during the period to which such excise tax relates bears to the aggregate sales of allproducts by such Selling Person subject to such excise tax;(C ) freight, insurance and other transportation charges to the extent included in the invoice price;(D ) amounts repaid, credited or accrued, or allowances or adjustments made, by reason of returns, rejections, or recalls, or because of chargebacks, retroactive price reductions, or billing errors ; 10(E ) reasonable and customary launch discounts, stocking fees and other discounts extended to wholesalers, distributors, chain drug stores and other third party organizations who distribute the Lixivaptan Product to pharmacies;(F ) reasonable and customary rebates and chargebacks to pharmacy benefit managers, federal, state, or localgovernments ( or their agencies or purchasers ), and managed health organizations ( including Medicaid rebates ) ; and(G ) any amounts actually written off or specifically identified as uncollectible in accordance with GAAP;solely to the extent the above deductions are taken in accordance with GAAP applicable to the particular Selling Person