definiens: shall mean ex vivo expansion and/or activation of T - cells using CD3x28 Beads ( whether or not in conjunction with one or more other beads, pa ramagnetic particles, steps or procedures ) for Ther apeutic Use ; provided, however, that the Field shall exclud e the following : - 2 - EXECUTION COPY ( a ) any and all uses in multiarray microfluidic chi p format analyzers ; and ( b ) any use in process or multiarray chip format th at comprises general or special applications in DNA / RNA - technology, including isolation of DNA / RNA fragments ( DNA / RNA probes ), peptide nucleic acids ( PNA ), plasmids, oligonucleotides, or any oth er subcellular components ( Mitochondria, Endoplasmic reticulum, Golgi apparatus, etc . ) 1.12 shall mean all patents and patent applications, and all additions, divisions, continuations, continuations in - part, pipeline protection, substit utions, reissues, extensions, registrations, patent term extensions, supplementary protection certificates a nd renewals of any of the above