definiens: ) from all Losses, as defined in Section 12.4 belo w, that they may suffer as a result of any claims, demands, actions or other proceedings m ade or instituted by any third party ( each, a ) directly arising from GENOCEA ’s use of the Produ ct ( including, without limitation, research, development, manufacture, marketing, sale or distri bution of any Combination Product or Combination Pr oduct candidate ), except to the extent arising from ( i ) t he failure of ONCOVIR, Manufacturer or any of their subcontractors to manufacture Product in accordance with the Specifications, GENOCEA ’s Purchase Order requirements or the Regulatory Standards or Regulat ory Requirements ( when applicable ) or ( ii ) any othe r breach of this this Agreement by ONCOVIR, or the negligenc e or willful misconduct of any of the ONCOVIR Indemnitees . If ONCOVIR intends to claim indemnific ation under this Section 10.1, ONCOVIR shall prompt ly notify GENOCEA in writing of the Third Party Claim, shall cooperate with GENOCEA in its control the de fense of such Third Party Claim, and shall cooperate with GENOCEA in such defense