definiens: means all Patent Rights that are Controlled by Licensor or any of its Affiliates, as of the Effective Date or at any time thereafter during the Term, and that are necessary or useful for the research, Development, manufacture, use, or Commercialization of a Licensed Compound or Licensed Product or that otherwise claim or cover the Licensor Know -How ( including, without limitation, Licensor ’s intere st in and to any Patents covering Joint Inventions ) . Listed on Schedule 1.42 are all Licensor Patents existing as of the Effective Date . Licensor shall update Schedule 1.42 from time to time to include any new Patent Rights that come to be Controlled by Li censor or an ) of its Affiliates al any time during the Term or after the Effective Date that are necessary or useful for the research, Development, manufacture, use, or Commercialization of a Licensed Compound or Licensed Product or that otherwise claim or cover the Licensor Know -How . Licensor Patents expressly exclude Patent Rights Controlled by an Affiliate of ’ Licensor who becomes an Affiliate through a merger or acquisition by or of Licensor, which Patent Rights were Controlled by such Affiliate immedi ately prior to such merger or acquisition ( any such Patent Rights, collectively, the )