definiens: and as used herein is used to define a release profile to effect delivery of an active over an extended period of time, defined herein as being between about 60 minutes and about 2, 4, 6 or even 8 hours . Extended release may also be defined functionally as the release of over 80 to 90 percent ( % ) of the active ingredient after about 60 minutes and about 2, 4, 6 or even 8 hours . Extended release as used herein may also be defined as making the active ingredient available to th e patient or subject regardless of uptake, as some actives may never be absorbed by the animal . Various extended release dosage forms may be designed readily by one of skill in art as disclosed herein to achieve delivery to both the small and large intesti nes, to only the small intestine, or to only the large intestine, depending upon the choice of coating materials and/or coating thickness