definiens: of a party means any other party that, directly or indirectly, through one or more intermediaries, controls, is controlled by, or is u nder common control with such first party . For purp oses of this definition only, and, with correlative me anings, the terms and will mean ( a ) the possession, directly or ind irectly, of the power to direct the management or p olicies of a party, whether through the ownership of voting secu rities or by contract relating to voting rights or corporate governance, and ( b ) the ownership, directly or indi rectly, of more than fifty percent ( 50 % ) of the vot ing securities or other ownership interest of a party ; provided that, if local law restricts foreign owner ship, control will be established by direct or indirect ownership of the maximum ownership percentage that may, unde r such local law, be owned by foreign interests . In additi on, Regulus Therapeutics, LLC will not be considere d an Affiliate of Isis