definiens: means, with respect to a Party ’s obligations under this Agreement, includingto Manufacture, Develop or Commercialize the Product, those efforts and resources consistent with the usual practices of suchParty in pursuing the manufacture, development or commercialization of its own pharmaceutical products that are of similarmarket potential as such Product, taking into account all relevant factors including product labeling or anticipated labeling, present and future market potential, past performance of such Product and such Party ’s other pharmaceutical products that areof similar market potential, financial return, medical and clinical considerations, present and future regulatory environmentand competitive market conditions, all as measured by the facts and circumstances at the time such efforts are due . Withoutlimiting the foregoing, Commercially Reasonable Efforts requires, with respect to such obligations, that the Party : ( i ) promptlyassign responsibility for such obligation to specific employee(s ) who are held accountable for progress and monitor suchprogress on an on - going basis, ( ii ) set annual objectives for carrying out such obligations, and ( iii ) allocate resources designedto advance progress with respect to such objectives