definiens: means ( i ) in relation to AMG827, the AMG827 TechnologyTransfer Agreement by and among Kyowa Hakko Kirin Co., Ltd., [COMPANY] and Kirin - [COMPANY], Inc., the Research, Development and Technology Disclosure Agreement : AMG827 by andamong Kyowa Hakko Kirin Co., Ltd., [COMPANY] and Kirin - [COMPANY], Inc., and the AMG827License Agreement between Kirin - [COMPANY], Inc., all dated October 29, 2010 and ( ii ) inrelation to AMG557 and AMG570, means the License Agreement by and between Amgenand Takeda Pharmaceutical Company Limited dated February 1, 2008, in each case asthe same have been amended and may be amended from time to time hereafter inaccordance with terms of this Agreement