definiens: . Commercially Reasonable Efforts means, with respect to theperforming Party, the carrying out of obligations of such Party in a diligent, expeditious and sustained manner, including theallocation of commercially reasonable personnel and financial resources, but in no event less than such level of resources that(in the case of SANOFI - AVENTIS ) pharmaceutical and major biotechnology companies or ( in the case of MERRIMACK)comparable biotechnology companies typically devote to their own internally discovered products, to which they solely ownall rights without financial obligations to any licensor, of similar market potential at a similar stage in its development orproduct life, taking into account scientific and commercial factors, including issues of safety and efficacy, product profile, difficulty in developing or manufacturing the Collaboration Compound or Licensed Product, competitiveness of alternativeThird Party products in the marketplace, the patent or other proprietary position of the Collaboration Compound or LicensedProduct, the regulatory requirements involved and the potential profitability for the performing Party of the CollaborationCompound or Licensed Product marketed or to be marketed