definiens: shall mean an Invention consisting of a new approach to therapy or treatment that has general applicability beyond use of such approach in relation to the Collaboration Target or specific Collaboration Target Combination ( i.e. the Optioned Target Combination ) that is targeted by a Program Antibody or Program Antibody Combination, as applicable . By way of non -limiting examples, a Generic Therapeutic Concept would include ( i ) an Invention consisting of combining [ * * * * * ] different Antibodies targetin g [ * * * * * ] different pathways such as an anti -apoptotic pathway, an anti - proliferative pathway and an anti - metastatic pathway to obtain a certain therapeutic effect ; and ( ii ) an Invention relating to a [ * * * * * ] . The term Generic Therapeutic Concept shall no t comprise Target Class Inventions . Further, the term Generic Therapeutic Concept shall not comprise the therapeutic or treatment approach to the extent that such approach applies to a Collaboration Target or specific Collaboration Target Combination