definiens: shall mean any and all Information and Inventions under the Control of [COMPANY] or any of itsAffiliates at any time during the period beginning on the Original Effective Date and ending on the last day of the Term that are necessaryor reasonably expected to be necessary for the Exploitation of a Combination Product or are disclosed to [COMPANY] or its Affiliates byJanssen or its Affiliates in the course of the performance of this Agreement or under the PVA ( or other safety - data exchange provisionscontained in any other Ancillary Agreement ) and are not generally known to Third Parties, including any such Information and Inventionsincluded in the [COMPANY] - Owned Collaboration Inventions, but excluding any and all ( a ) such Information and Inventions to the extentdisclosed by published [COMPANY] Patents, ( b ) Joint Know - How and ( c ) ( i ) business information, medical education materials, promotionalmaterials and marketing and strategic studies, or ( ii ) information relating to the validity or enforceability of any Patents or any freedom tooperate analysis