definiens: means exerting such good faith and sustained eﬀorts, employing suchresources ( including suﬃcient ﬁnancial, human and material resources ), and exercising prudent business andscientiﬁc judgment, as would normally be exerted or employed by a similarly situated company / biopharmaceuticalentity for a product or service of similar market potential, proﬁt potential and strategic value at a similar stage of itsproduct or service life, including : ( a ) promptly assigning responsibility for such matters to speciﬁc employee(s ) who areheld accountable for progress and monitor such progress on an on - going basis ; ( b ) setting and consistently seeking toachieve speciﬁc, meaningful and measurable objectives for carrying out such matters ; and ( c ) making andimplementing decisions and allocating resources designed to advance progress with respect to such matters