definiens: shall mean the level, type and quality of efforts t hat would be applied by a pharmaceutical company having resource s and expertise similar to the applicable Party, to perform its obligations hereunder, with respect to a compou nd or product developed by such company, including its obligation to Develop, seek and obtain Regulatory A pprovals for, manufacture and Commercialize the Pro duct, all to the extent consistent with reasonable busine ss practices, for example, in light of the reasonab le commercial potential of the Product in the Territory . Without limiting the foregoing, Commercially Reasonable Eff orts shall require that such Party devote appropriate resource s and personnel with an appropriate level of educat ion and experience similar to what the Party usually devote s to products in comparable markets having similar commercial potential to the Product in the Territory . Commerci ally Reasonable Efforts are meant to apply to the T erritory as a whole, rather than to any part of it separately, recognizing that obtaining Regulatory Approval ( inc luding, e.g., by accepting Product Labelling different from the P roduct Labelling approved by the EMA, or by setting maximum prices or reimbursement value with potential negati ve cross reference pricing impact ) or effecting Commercialization of the Product in one or more spe cific countries of the Territory, may impact in an adverse manner on the economic success of the Product in th e Territory as a whole for the applicable Party