definiens: means : ( a ) any Know- How Controlled by Miragen, its Affiliates or Sublic ensees during the Term and prior to the termination of this Agreement with respect to a Terminated Miragen Target [ * ], that relates to the subject matter described in clause ( i ), ( ii ) or ( iii ) in subsection ( b ) below ; and ( b ) any Patents Controlled by Miragen, its Affiliates or Sublicensees during the Term and prior to the termination of this Agreement with respect to a Ter minated Miragen Target [ * ], that claim or cover ( i ) any Miragen Target in such Terminated Miragen Targ et [ * ] ( including the sequence, expression or method of producing or purifying such Miragen Target ), ( ii ) any research tool relating to such Miragen Target, including any mate rial or process for preparing such Miragen Target, any assay reagent prepared from such Mirage n Target, any process for its preparation, or any method of using such Miragen Target, material o r assay reagent to screen, assay, select or otherwise identify any composition of matter that b inds to such Miragen Target and alters the activity of such Miragen Target or ( iii ) the use of any compound containing an LNA Monomer f or therapeutic purposes wherein the therapeutic mechan ism of action is mediated by the binding of such compound to such Miragen Target and the result ing regulation or modulation of such Miragen Target