definiens: means the equivalent of the work of one ( 1 ) employee full time for one ( 1 ) year ( consisting of at least a total of forty - five and one half weeks 45.5 weeks or one thousan ei t hundred twen 1 820 hours er ear ( excluding vacations and holidays ) of work on or directly related to the Collaboration ), carried out by an Isis employee or a [COMPANY] Collaboration FTE, or Third Party mutually agreed upon by the Executive Committee . Overtime shall not be counted toward the number of hours that are used to calculate the FTE contribution . No one person shall be permitted to account for more than one ( 1 ) FTE . Scientific work on the Collaboration to be performed by Isis employees, [COMPANY] Collaboration FTEs, or mutually agreeable Third Parties can include, but is not limited to, experimental laboratory work, recording and writing up results, reviewing literature and references, and holding scientific discussions