definiens: ( as defined in the IL-8 Agreement ) or ( as defined in the 1L-8 Agreement ) and licensed to [COMPANY] under the IL-8 Agreement unless and until the 1L-8 Agreement is terminated pursuant to Section 1.4(a ) thereof . " BOS - BUS:301805.1 48 5 . Section 1.4(d ) . The following sentence is added as a new paragraph at the end of Section l.4(d ) of the Agreement : " Notwithstanding the foregoing, this Section 1.4(d ) shall not apply to inhibitors of IL-8 . In the event that Warner identifies a compound hereunder that it wishes to optimize for IL-8 activity, it shall do so pursuant to the IL-8 Agreement.1.4(e ) . " Equity Reduction . The total dollar amount of [COMPANY] capital stock that Warner may be required to purchase ( and [COMPANY] may be required to sell ) pursuant to Sections 1.4(b ), 1.4(c ) and/or 1.4(d ) shall be reduced by an amount of $ 2,500,000 in the aggregate, to be applied to the first and each successive such purchase until such amount is exhausted