definiens: shall mean, with respect to the efforts to be expended by a Party to achieve a stated objective, the good faith, diligent efforts to accomplish such objective as such Party would nonnally use to accomplish a similar objective under similar circumstances, it being understood and agreed that, with respect to efforts to be expended with respect to development or commercialization of a Collaboration Compound or Product hereunder, such efforts shall be substantially consistent with [ those efforts and resources commonly used by such Party for any other product ( an ) owned by it or with respect to which it may have rights, which other product is at a similar stage in its development or product life and is of similar market potential as such Collaboration Compound or Product . Commercially Reasonable Efforts shall be determined on a market - by - market and product - by - product basis in view of conditions prevailing at the time, and evaluated taking into account all relevant factors, including without limitation, the efficacy, safety, anticipated approved labeling, competitiveness of alternative products that are in the marketplace or under development and other technical, scientific, . legal and . competitive factors . ] It is anticipated that the level of effort may change from time to time