definiens: means the average of the monthly annual percentage changes in the Inflation Indexfrom September of the preceding Year to August of the then current Year . For example, at the end of 2019the new Inflation Percentage would be calculated as follows ( figures are for illustration only):From : Month - YearTo : Month - YearAnnual Percentage ChangeSeptember - 2017September - 20180.7 % October - 2017October - 20181.1 % November - 2017November - 20181.0 % December - 2017December - 20180.8 % January - 2018January - 20190.8 % February - 2018February - 20191.1 % March - 2018March - 20191.1 % April - 2018April - 20191.5 % May - 2018May - 20191.7 % June - 2018June - 20191.4 % July - 2018July - 20191.2 % August - 2018August - 20191.1 % Inflation Percentage1.13 % Calculation : CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [ * * * ], HAS BEEN OMITTED BECAUSECARA THERAPEUTICS, INC . HAS DETERMINED THE INFORMATION ( I ) IS NOT MATERIAL AND ( II ) WOULD LIKELY CAUSECOMPETITIVE HARM TO CARA THERAPEUTICS, INC . IF PUBLICLY DISCLOSED