definiens: means : Exhibit D Additional Definitions B cell maturation antigen ( BCMA, gene name TNFRSF 1 7 ) Approved symbol TNFRSF17 Approved name tumor necrosis factor receptor superfamily, member 17 HGNCID HGNC:11913 Previous symbols & names BCMA Synonyms BCM, CD269, TNFRSF13A Locus type gene with protein product Chromosomal location 16p 13.1 Gene family CD molecules Tumor necrosis factor receptor superfamily HCOP Orthology Predictions for TNFRSF 17 BLUE-168 means : The anti - BCMA product candidate known as bb 2121 means : An anti - BCMA product candidate [ other than bb 2121, which uses an scFv sequence that is of human origin or is a non - human sequence that has been humanized to potentially lessen immunogenicity . ] BLUE-169 [ Lead Product Candidate Exhibit E Collaboration Plan bluebird bio wiD undertake a Ilhase I clinical trial to evaluate bb212l . bb212l drug product is defined as autologous T lymphocytes ( T ceUs ) transduced ex - vivo with anti - BCMA02 CAR lentiviral vector encoding the chimeric antigen receptor ( CAR ) targeted to human B cell maturation antigen ( anti - BCMA CAR ) suspended in cryopreservative solution in the final container for the intended use . bb2l2l active drug substance is defined as anti - BCMA CAR+ T cells