definiens: as defined in Sec . 201(g)(I)of the Act, and ( d ) is marketed, promoted, sold or used under the supervision of licensed skin care professionals, as verified by Licensor, including medical doctors, medical nurses, physician assistants, aestheticians, and cosmetologists, specifically for cosmetic proceduresof the skin, including but not limited to skin resurfacing, skin debriding, skin conditioning, skin rejuvenation and the prevention andmaintenance of aging, hyperpigmentation, scars and bruises, whether for use in such skin care professional ’s office, or asrecommended by such skin care professional, for at home use . For the avoidance of doubt, Licensor and [COMPANY] Medical, LLC may onlysell products directly to licensed skin care professionals for in - office use or for resale to patients . ”The following definitions are hereby added to the License Agreement : shall mean any Licensed Product sold by Dermata that contains Sponge in combination with an activeingredient with a molecular weight greater than or equal to [ * * * ] . ” means any Know - How related to the harvest, storage, and handling of Sponge from its initial harvest throughpreparation as a pharmaceutical ingredient or product in the form of a raw material that is useful or necessary to Exploit a LicensedProduct, including a HMW Combination Product . ” means Know - How relating to the development and submission for Regulatory Approval of anySponge - containing product or regimen according to the FDA Botanical Drug Development Guidance for Industry ( 2016 ) or the Guidancefor Industry on Botanical Drug Products ( 2004).”All defined terms in the License Agreement ( as amended above ) shall have the same meanings in this Amendment