definiens: means the total invoic ed amount of all worldwide sales of Collaboration Product(s ) by Agour on, its Affiliates or Sublicensees, to a Third Party, less ( a ) c ustomary trade, quantity, or cash discounts and commissions allowed and taken by brokers or agents, ( b ) amounts repaid or credited by reason o f rejection or returns, as well as rebates, chargebacks, retroactive price reductions and allowances, ( c ) sales, use and/or other ta xes, import and/or export customs duties, and other similar governme ntal charges paid, but not including income taxes, and ( d ) to the ext ent separately stated on purchase orders, invoices, or other docume nts of sale, insurance costs and outbound transportation charges prepai d or allowed related to shipment of Collaboration Product(s ) . Net Sales Revenue excludes : ( a ) the transfer of reasonable and customary q uantities of free samples of Collaboration Product(s ), ( b ) the transfer of Collaboration Product(s ) as clinical trial materials, other than fo r subsequent resale ; and ( c ) use by [COMPANY], its 5 Affiliates or Sublicensees of Collaboratio n Product for any purpose connected with the securing of regulatory approval or validating of a manufacturing process or the obtaining o f other necessary marketing approvals for Collaboration Prod uct ( unless such Collaboration Product is subsequently sold )