definiens: means ( a ) the bi - specific antisense inhibitor of insulin - like growth factor binding protein-2 and insulin - like growth factor binding protein-5 having the sequence 5'-CAGCAGCCGCAGCCCGGCTC-3 ' where underlined residues are 2'-methoxyethylnucleosides ( MOE ) and phosphorothioate linkages throughout ; and ( b ) any 19 CONFIDENTIAL TREATMENT other ASO that is covered by or based on any OGX intellectual property as at the Effective Date or during the Agreement Term and primarily directly modulates the expression of insulin - like growth factor binding protein-2 and insulin - like growth factor binding protein­S, solely or as bi - speci fic inhibitors, but excluding compounds within the scope of OGX-011, Licensed Compounds, Licensed Products, and OGX Product Specific Intellectual Property