definiens: means the aggregate amounts invoiced for sales or transfers for value of Licensed Products by Alexo, its affiliates orany of its sublicensees to an independent third party distributor, agent or end user ( other than sales of Licensed Products at costby Alexo, its affiliates or sublicensees to a third party for use in a clinical study prior to regulatory approval of such LicensedProduct ) less deductions selected as appropriate from : ( i ) customary discounts in the trade for quantity purchased, promptpayment or wholesalers and distributors ; ( ii ) credits or refunds separately and actually credited or paid to customers for defective, spoiled, damaged, outdated or returned Licensed Products that do not exceed the original invoice amount ; ( iii ) discountsmandated by, or granted to meet the requirements of, applicable state, provincial or federal law, paid or credited to a wholesaler, purchaser, third party or other contractee including required chargebacks and retroactive price reductions ; ( iv ) rebates actuallypaid or credited to any governmental agency ( or branch thereof ) or to any third party payor, administrator or contractee ; ( v ) sales, excise or use taxes paid, absorbed or allowed excluding net income tax, imposed upon the sale of the Licensed Product ; and(vi ) prepaid outbound transportation expenses and transportation insurance premiums that are separately billed to the customeror prepaid