definiens: means, with respect to a Party ( directly or through Aﬃliates orSublicensees ) performing activities under this Agreement, such reasonable, diligent, and good faith eﬀorts as such Partywould normally use to accomplish a similar objective under similar circumstances, but no less than the eﬀorts and resourcescommensurate with those eﬀorts commonly used in the biopharmaceutical industry by a company of comparable size inconnection with the development, manufacture or commercialization of biopharmaceutical products of similar risk proﬁle, market potential, or proﬁt potential at a similar stage of development or commercialization in its product lifecycle, taking intoaccount [ * * * ], including [ * * * ] in each case, based on [ * * * ], but, with respect to [ * * * ], not taking into account [ * * * ]