definiens: means ( A ) with respect to AVEO, any human clinical trial or registry either(i ) required to be carried out by a Regulatory Authority in the AVEO Territory for the purpose of post - marketing surveillanceof Licensed Product in the AVEO Territory or ( ii ) otherwise requested by Regulatory Authorities in the AVEO Territory afterRegulatory Approval of Licensed Product in the AVEO Territory in an indication, designed to obtain additional informationregarding Licensed Product ’s risks, benefits and optimal use of that Licensed Product in such indication, and ( B ) with respectto [COMPANY] Idec, any human clinical trial or registry either ( i ) required to be carried out by a Regulatory Authority in theLicensed Territory for the purpose of post - marketing surveillance of Licensed Product in the Licensed Territory or(ii ) otherwise requested by Regulatory Authorities in the Licensed Territory after Regulatory Approval of Licensed Product inthe Licensed Territory in an indication, designed to obtain additional information regarding Licensed Product ’s risks, benefitsand optimal use of that Licensed Product in such indication . For purposes of clarity, a clinical trial of Licensed Product in anindication for which such Licensed Product is not approved shall not be considered Post - Approval Clinical Study even if suchtrial occurs after such Licensed Product is approved in another indication