definiens: shall mean : ( a ) any compound that is first identified or discovered, by Company or any of its Affiliates(whether for Company ’s or such Affiliate ’s account or on behalf of a Sublicensee or Partner ) or by any Sublicensee, throughstructure - based drug discovery using a Qualified Structure ; ( b ) any compound that is first identified or discovered, by Company or any of its Affiliates(whether for Company ’s or such Affiliate ’s account or on behalf of a Sublicensee or Partner ) or by any Sublicensee, throughin silico screening using a Qualified Structure ; ( c ) any compound that ( i ) is identified or derived, in whole or in part, from the use, byCompany or any of its Affiliates ( whether for Company ’s or such Affiliate ’s account or on behalf of a Sublicensee or Partner)or by any Sublicensee, of a Qualified Structure of a particular G protein - coupled receptor ( ) to discover, modify, enhance, reduce or otherwise optimize the chemical or pharmaceutical properties or elements of a starting compound havingactivity against such GPCR or another GPCR of the same subtype ( e.g