definiens: or shall mean methods utilizing Microfluidic Chips, capillary electrophGresis, ACLAmate or MAS instruments which involve : ( i ) one two or a multi licity of candidate compounds are contacted with the target, the result of which contact may ctiange ttie activit 0 ttie targe U[!10 thir olecu e ), said activity being determined based upon subsequent analysis after elec;:troQh retic separation o~ tMe substrate/ roduct formed . ( ii ) one . two Gr a multi licit of candidat ;, ; .e-:-;- " ", compounds are contacted with the target, the result of which contact on the il'1i : lin!lJ affiraity of at ira olecule to t e target ( ) being determined based upon subsequent analysis after electroQhor ~tic separation o · he biomolec la c Ie 0 eo ( iii eTag Technology, and c(iv ) C ag Technolog ~