definiens: shall mean ( a ) with respect to TMC278, an API that ( i ) has the same [ ~tive Moiety ] as TMC278, ( ii ) is at a dose which is the therapeutic equivalent to 25 mg 7 [ ] = Certain confidential information contained in this document, highlighted and marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 24b-2 of the Securities Exchange Act of 1934, as amended . CONFIDENTIAL TREATMEl'ot'T REQUESTED U"l > ER 17 C.F.R. § § 200.80 ( b)(4 ) AND 230.406 rilpivirine hydrochloride and ( iii ) is presented in a tablet, capsule or gel form intended for once­daily oral dosing in adults ; ( b ) with respect to TDF, an API that ( i ) has the same [ iA.ctive MoietY ] as TDF, ( ii ) is at a dose which is the therapeutic equivalent to 300rng TDF and ( iii ) is presented­in a tablet, capsule or gel form intended for once - daily oral dosing in adults ; and ( c ) with respect to FTC, an API that ( i ) has the same [ \Active MOieij ] as FTC, ( ii ) is at a dose which is the therapeutic equivalent to 200rng FTC and ( iii ) is presented in a tablet, capsule or gel form intended for once - daily oral dosing in adults