definiens: mean all patents, patent applications, invention disclosures, certificates of invention and applications for cert ificates of invention, owned or Controlled by Sunes is or its Affiliates as of the Agreement ’s Effective Date and /or during the term of the Agreement ( as described in Exhibit 1.35 hereto ), and all information, materials and ot her subject matter, and improvements thereof, relat ing to ( i ) mutants or the use thereof in screening, ( ii ) the u se of novel protein engineering techniques and thei r application in drug discovery, ( iii ) target - directed fragment d iscovery and maturation to produce drug leads, incl uding monophores, extenders and fragments, and monophore, extender and fragment libraries for such purposes, ( iv ) covalent tethering and techniques related thereto ( e.g., NMR, X - ray, mass spec . AUC, Biacore ) and its use to discover fragments and test binding hypotheses of f ragments and leads, or ( v ) dynamic and other combin atorial chemistries related to proteins, as well as any div isions, continuations, continuations - in - part, reiss ues, reexaminations, extensions, supplementary protectio n certificates, and other governmental actions whic h extend any of the patent applications, patents, invention disclosures, certificates of invention or certifica tes of invention applications above, and all foreign counterparts to any of the foregoing