definiens: means any and all Materials, including RNPComplexes ( including any components or sequences thereof ), compositions ofmatter, cells and cell lines, assays, imaging agents used to assess DNA modification, reagents, DNA sequences, internal controls and any other physical, biological orchemical material, in each case, that are ( a ) Controlled by Editas or its Affiliates andrelated to or necessary or reasonably useful to Research, Develop, Manufacture, Commercialize or otherwise exploit any Collaboration RNP Complex or otherwiserelated to any Collaboration Target ; and ( b)(i ) created, conceived, discovered, developed, generated, invented, made or reduced to practice, by or on behalf ofEditas ( or any of its Affiliates ), solely or jointly with any Third Party, in the performanceof the Research Program or any other obligations under this Agreement or ( ii)otherwise included or utilized by or on behalf of Editas or any of its Affiliates in theperformance of the Research Program or any other obligations under this Agreement