definiens: means, with respect to Licensee ’s obligations under theAgreement to Exploit the Licensed Compounds and Licensed Products, the level of efforts in carryingout such obligation in a sustained manner that is at least consistent with the efforts that a similarlysituated biotechnology company would typically devote to compounds and products of similarcommercial and scientific potential at a similar stage in their lifecycle, based on market conditionsthen prevailing and taking into account expected and actual cost and time to Exploit the LicensedCompounds and Licensed Products, the potential profitability of the Licensed Compounds andLicensed Products, the competitiveness of the marketplace, the performance of other products thatare of similar market potential, the likely timing of other products ’ entry into the market and all otherrelevant legal and technical factors . The expenditure of Commercially Reasonable Efforts requires, with respect to a particular task or activity in Exploiting the Licensed Compounds and LicensedProducts, that Licensee : [ * ] . The expenditure of Commercially Reasonable Efforts requires Licenseeto [ * ] given the commercial and scientific potential of the Licensed Compounds and LicensedProducts, and [ * ] for purposes of determining Licensee ’s expenditure of Commercially ReasonableEfforts