definiens: shall mean any pharmaceutical product that contai ns one or more Compound(s ), alone or as a Combination Product, including, in each case, all formulations, line extensions and modes of admi nistration, including any pharmaceutical product containing any formulation of one or more Compound(s ) with poloxa mer CRL1005, but excluding, in each case, any formulati on with the Vaxfectin Adjuvant . shall mean any pharmaceutical product that contains one or more Compound(s ) in combination with one or more other therapeutically and/or prophylactically activ e ingredient(s ), whether packaged together or inclu ded in a prime - boost regimen or in the same therapeutic form ulation, including, in each case, all formulations, line extensions and modes of administration, but excludi ng, in each case, any formulation with the Vaxfecti n Adjuvant . For clarification, poloxamers, other deli very systems and adjuvants shall not be considered therapeutically and/or prophylactically active ingr edients