definiens: means the gross amount invoiced or otherwise charged by TGTX, its Affiliates and Sublicensees ( ) to Third Parties for sales of a Licensed Product, less : ( a ) Normal and customary trade, quantity, cash and discounts and credits allowed and taken ; ( b ) Discounts, refunds, rebates, chargebacks, retroactive price adjustments and any other allowances given and taken which effectively reduce the net selling price, including, without limitation, Medicaid rebates, institutional rebates or volume discounts ; 7 ( c ) Product returns and allowances granted to such Third Party ; ( d ) Normal and customary administrative fees paid to group purchasing organizations ( e.g., Medicare ) and government - mandated rebates ; ( e ) Shipping, handling, freight, postage, insurance and transportation charges, but all only to the extent included as a separate line item in the gross amount invoiced ; ( f ) Any tax, tariff or duties properly imposed on the production, sale, delivery or use of the Licensed Product, including, without limitation, sales, use, excise or value added taxes and customs and duties ; ( g ) Allowances for reasonable and verifiable distribution expenses ; and ( h ) Bad debt actually written off during the accounting period, as reported by the Selling Party in accordance with GAAP, applied on a consistent basis