definiens: shall mean, with respect to the Product, the gross amount invoiced for the Product by Kirin and/or its Affiliates, if any, in arm 's length sales to Third Parties, commencing with the First Commercial Sale, less deductions for : ( i ) trade, quantity and/or cash discounts, allowances and rebates actually allowed or given ; ( ii ) freight, postage, shipping containers, shipping insurance and other transportation expenses ( if separately identified in such invoice ) ; ( iii ) credits or refunds actually allowed for rejections, defects or recalls of such Product, outdated or returned Product, or because of rebates or retroactive price reductions ; and ( iv ) sales, value - added, excise taxes, tariffs and duties, and other taxes directly related to the sale, to the extent that such items are included in the gross invoice price ( but not including taxes assessed against the income derived from such sale )