definiens: means all out - of - pocket costs and expenses directly related to the Existing Productsthat are paid to Third Parties by Impax ( other than the costs and expenses of a Third Party sales force and for purchase ofExisting Product samples ) in connection with the Commercialization of the Existing Products under this Agreement, including : ( i ) local marketing and marketing research costs ; ( ii ) non - personal Promotion and advertising costs ( including costsof direct - to - consumer advertising, journal advertising, Marketing Materials, direct mail, reminder promotions, coupons anddiscount cards and web - based promotions ) ; and ( iii ) public relations . Promotional Spend excludes salaries and other variablecosts of Detailing the Existing Products and the other Sales Force costs . For the avoidance of doubt, Promotional Spendexcludes all costs and expenses for acquisition of Existing Product samples for distribution