definiens: means with respect to the efforts to beexpended by ASLAN under this Agreement, active and diligent efforts and resources to developand commercialize Products, and to obtain the optimum commercial return for such Productsthroughout the world consistent with the exercise of prudent scientific and business judgment, asare typically applied by ASLAN ( and in any event not less than are typically applied bybiotechnology and/or pharmaceutical companies that are similar in size and financial resourcesas ASLAN ) when actively and diligently pursuing development or commercialization of its othersimilarly important innovative pharmaceutical products of comparable commercial potential, taking into account all relevant factors including, as applicable, stage of development, efficacyand safety relative to competitive products in the marketplace, actual or anticipated governmentalapproved labeling, the nature and extent of market exclusivity ( including patent coverage andregulatory exclusivity ), cost and likelihood of obtaining Marketing Approval in major markets, andactual or projected profitability, but not taking into account ( a ) any other pharmaceutical productsuch Party is then researching, developing or commercializing, alone or with one or morecollaborators, or ( b ) any payments required to be made to the other Party hereunder . ASLANshall perform its obligations under this Agreement with respect to development andcommercialization of Products solely in the best interests of maximizing the success of suchProducts, and not in the present or future interest of other products of ASLAN or its Affiliates otherthan Products