definiens: means the Patents and Know - How that ( i ) are Controlled by [COMPANY] and(ii ) are necessary or reasonably useful for the development, making ( and having made ), offering for sale, sale, andimporting of BioFene itself, including, but not limited to, the escrowed BioFene Production Strain and any Patents andKnow - How related to the genetic engineering of such BioFene Production Strain, the fermentation methods for makingBioFene, the methods of recovery of BioFene from fermentation broth, the processes of isolating BioFene directlyfrom fermentation broth, and the methods of purifying BioFene . The term also includes any and all Joint BioFene Manufacturing Improvements and Novvi LLC BioFene ManufacturingImprovements, but expressly excludes any Novvi LLC BioFene Transformation Technology means any and all inventions, discoveries, data, and information, whether or notcopyrightable or patentable, conceived, reduced to practice, made, observed or developed ( together with allintellectual property rights related thereto ) by or on behalf of [COMPANY] or its Affiliates or sublicensees, solely or jointlywith others, in violation of the license granted to it in Section 2.2