definiens: means that certain Collaboratio n and License Agreement, dated as of August 29, 2013, by and between the Seller and Licensee, a s amended by that certain Amendment No . 1, dated as of August 24, 2015, that certain Amendment No . 2, date d as of November 28, 2016, Amendment No . 3, that ce rtain Amendment No . 4, dated as of January 29, 2018, that certain Amendment No . 5, dated as of April 30, 201 8, that certain Amendment No . 6, dated as of February 1, 20 19, that certain Amendment No . 7, dated as of Decem ber 5, 2018, and that certain Amendment No . 8, dated as of July 4, 2019 . means the KHK Patent Rights, the KHK Know - How, the KHK Inventions and Licensee ’s interest in the Joint Inventions