definiens: means 30 June and 31 December in each calendar year ; 1 means a therapeutic product approved for sale by th e relevant regulatory authority ; means any entity that, directly or indirectly, thro ugh one or more intermediates, is controlled by, contro ls, or is under common control with a party . For purpos es of this definition only, the term, or shall mean the possession of the p ower to direct or cause the direction of the management and policies of an entity, whether by ownership of voti ng stock or partnership interest, by contract or other wise, including direct or indirect ownership of more than 50 percent of the voting interest in the entity in que stion ; the cumulative aggregate Net Selling Price of Chargeable Transactions in the relevant calendar ye ar ( 1 January to 31 December ) ; the hypoxic cell cytotoxin known by the chemical name 1,4 - bis { [ 2-(dimethylamino - N - oxide ) ethyl]amino ) 5,8 dihydroxy - anthracene-9,10- dione and salts thereof ; means an irrevocable, non - exclusive, world - wide licence with full rights to sub - license, under the Licensee Inventions and the Licensee Results ; means the sale or other disposal of a Licensed Prod uct by or on behalf of the Licensee or a Sub - licensee o r their respective Affiliates during the longer of th e following periods, namely : ( 1 ) the period in a country where such manufactu re or sale or other disposal would otherwise infringe the Valid Claims of Patents which is for the life of such Patents ; or ( 2 ) in a country in which Licensed Products are sold or otherwise disposed of where there are no Valid Claims of Patents or such Valid Claims of Patents have expired, lapsed or been revoked, the period which runs for [ * ] years from First Commercial Sale ; [ * ] Certain information on this page has been omitt ed and filed separately with the Securities and Exchange Commission . Confidential treatment has bee n requested with respect to the omitted portions