definiens: , in relation to a Licensed Product, means the gross invoice price of the Licensed Product supplied, sold, hired or otherwise disposed of by AVEO, its Affiliates or, with respect to Licensed Therapeutic Products, any Sub - licensee of AVEO or its Affiliates ( each of the foregoing, the ) to a Third Party in an arm’slength transaction, less : ( a)tariffs, taxes, duties or other government charges ; freight, shipping, insurance, and other transportationexpenses borne by the Seller on the sale of the Licensed Products and included in the invoice ; ( b)normal and customary trade, cash and quantity discounts, allowances, and credits allowed or paid by theSeller, in the form of deductions actually allowed and taken with respect to sales of such LicensedProduct ( other than deductions offered as part of a package of products that includes any LicensedProduct ) ; ( c)retroactive price reductions, allowances or credits granted and taken on account of price adjustments, recalls, rejection, billing errors, or return of Licensed Products previously sold ; ( d)discounts, chargeback payments, rebates and reimbursements granted and taken with respect to sales ofsuch Licensed Product to managed health care organizations, group purchasing organizations or otherbuying groups, pharmacy benefit management companies, health maintenance organizations, federal, state / provincial, local or other governments, and any other providers of health insurance coverage, healthcare organizations or other health care institutions ( including hospitals ), health care administrators orpatient assistance or other similar programs ( other than discounts, chargeback payments, rebates, orreimbursements offered as part of a package of products that includes any Licensed Product ) ; and ( e)amounts previously included in Net Sales of Licensed Product that are not collected ( and written off asuncollectible ) after reasonable collection efforts, provided that such amounts shall be no greater than[**]%