definiens: shall mean Patent Rights owned, licensed or Controlled byCytovia ( including its Affiliates, Licensors or its Licensees ) ~i<:h cover [COMPANY] Compounds, Agreement Compounds, Products or Screens or the use of any of the foregoing as of the EffectiveDate or during the Collaboration Perio~1.20 shall mean\§'tovia Patent Rights and [COMPANY] KnOW - HOWJ1.21 shall mean a'chemical that has activity in a Screen and that is created ' byor for [COMPANY] based on a Hit, including(i ) any structure based on the structure of a Hit ( or anyone of the active substructures, if more than one exist),(ii ) any structure based on activity data derived from a Hit,(iii ) a chemical derivative of either a Hit, or a Development Candidate or(iv ) any molecule with a structure that falls within the scope - Of"any Villid Claimowned, licensed or Controlled by [COMPANY] that encompasses a Hit