definiens: means ( A ) monitoring and coordinating all regulatory actions, communicationsand filings with, and submissions to, all Regulatory Authorities with respect to a Licensed Compound, LicensedProduct and/or Licensed Product Biomarker, and ( B ) interfacing, corresponding and meeting with the RegulatoryAuthorities with respect to a Licensed Compound, Licensed Product and/or Licensed Product Biomarker . Each Partyshall use Commercially Reasonable Efforts to conduct Regulatory Interactions for which such Party is responsible inthe JDCT hereunder in accordance with the JDCT Development Plan and JDCT Commercialization Plan, asapplicable . API shall use Commercially Reasonable Efforts to conduct Regulatory Interactions for which API isresponsible in the Royalty - Bearing Territory hereunder in accordance with the ASTELLAS RBT Development Planand ASTELLAS RBT Commercialization Plan, as applicable