definiens: shall mean all Intellectual Property Rights owned or held by [COMPANY] prior to the Effective Date of thisAgreement, or developed or obtained by [COMPANY] after the Effective Date of this Agreement independently of MRC ( asdetermined by inventorship under US law with respect to any patents and patent applications ), including withoutlimitation all such Intellectual Property Rights ( a ) related to MASP-2 obtained by [COMPANY] under license from Leicester(including without limitation all MASP-2 and MAp19 rights conveyed under the [COMPANY] - Leicester Agreement of 10June 2004 ) or developed by [COMPANY] independently of MRC by [COMPANY] and ( b ) related to methods and pharmaceuticals orother agents to inhibit pain, inflammation, cartilage loss, vasospasm, smooth muscle spasm, restenosis, or tumor celladhesion, and/or to accelerate recovery of joint motion and function, for use in surgical procedures ( including withoutlimitation arthroscopic, cardiovascular, urologic and general surgical procedures ), other medical procedures, and/or fortreatment of cartilaginous disorders, and drug delivery methods and systems