definiens: means the specific direct costs incurred by a Commercializing Party directly on account of a Profit Share Product for marketing, promotion, advertising, promotional materials, professional education, product related public relations, relationships with opinion leaders and professional societies, market research ( before and after product approval ), healthcare economics studies, post - marketing studies not required to maintain product approvals ( e.g., investigator sponsored trials, product registries and medical information ), and other similar v [ 1 ~ CERTAI/\ CONFUJE:'>ITlAL lSFORMAliOr- ; CO:'>lTAINED 1:- ; TIII~ DOCl'MENT . M">RKED BY BRACKETS, IS FILED WITH THE SEClIRITIES AND EXCHANGE COMMISSIO:'>l Pl : RSl'ANT ro Rl LE 24B·2 Of THE SECl'RITIES EXCIIANGE ACT OF 19J4 . AS AME"DED