definiens: means technical and other information or knowledge made by any person employed by Licensor who isidentified as an inventor or reporting to an inventor or subordinate to an inventor under the patents existing or arising fromSections 1.12 b, c, d, and a of the Licensed Technology, which Know - How is dominated by any claim under the patentsexisting or arising from Sections 1.12 b, c, d, and e of the Licensed Technology such that it can not be practiced withoutinfringing on a valid claim in the Licensed Technology, and which Know - How is created prior to or after the Effective Date ofthis Agreement which is not in the public domain including all trade secrets, information and knowledge comprising orrelating to concepts, non patentable discoveries, data, designs, formulae, methods, models, assays, research plans, procedures, designs for experiments and tests and results of experimentation and testing ( including results of research or development)processes ( including manufacturing processes, specifications and techniques ), laboratory records, chemical, clinical, analyticaland quality data, trial data, case report forms, data analyses, reports, manufacturing data, or summaries and informationcontained in submissions to and information from regulatory authorities, and includes any rights including copyright, database or design rights protecting any of the foregoing . The fact that an item is known to the public shall not be taken toexclude the possibility that a compilation including the item, or a development relating to the item, is or remains not knownto the public . Notwithstanding the foregoing, Know - How expressly excludes new patentable or copyrightable inventionsarising after the Effective Date of the License Agreement not included within the definition of Improvements