definiens: means ( i ) in relation to AMG827, the AMG827 TechnologyTransfer Agreement by and among Kyowa Hakko Kirin Co., Ltd., [COMPANY] and Kirin - [COMPANY], Inc.,the Research, Development and Technology Disclosure Agreement : AMG827 by and among KyowaHakko Kirin Co., Ltd., [COMPANY] and Kirin - [COMPANY], Inc., and the AMG827 License Agreementbetween Kirin - [COMPANY], Inc., all dated October 29, 2010 and ( ii ) in relation to AMG557, means theLicense Agreement by and between [COMPANY] and Takeda Pharmaceutical Company Limited datedFebruary 1, 2008, in each case as the same have been amended and may be amended from time totime hereafter in accordance with terms of this Agreement