definiens: means any and all Patents ( other than any Patents licensed to ARYx under theUniversity of Toledo Agreement ) ( a ) ( i ) that constitute or issue from patent applications ( 1 ) that are filed in the U.S. orany foreign jurisdiction prior to the Effective Date or ( 2 ) that claim priority to a patent application filed in the U.S. orany foreign jurisdiction prior to the Effective Date ( but excluding any claims not entitled to a priority date prior to theEffective Date ), ( ii ) that are Controlled by ARYx or any Person that is an Affiliate of ARYx on the Effective Date, and(iii ) the practice of which is reasonably required or useful for the Exploitation of Licensed Products, or ( b ) that areBlocking Patents . For the avoidance of doubt, ARYx Patents include the Patents listed in Exhibit A and exclude anyPatents relating to the [COMPANY] Inventions