definiens: within the meaning of Article 9 of the UC C of any applicable items of Collateral, ( C ) execut e and deliver such Intellectual Property Security Agreeme nts as are requested by CHRP within ten ( 10 ) Busine ss Days of any such request and ( D ) deliver such other inst ruments or notices, in each case, as may be necessa ry or desirable, or as CHRP may reasonably request, in or der to perfect and preserve the security interests granted or purported to be granted hereby, 4 ( ii ) furnish to CHRP from time to time statements a nd schedules further identifying and describing the Collateral and such other reports in connection with the Colla teral as CHRP may reasonably request, all in reason able detail, ( iii ) at CHRP ’s reasonable request, appear in and defend any action or proceeding that may aff ect the title of [COMPANY] to or CHRP ’s security interest in all or any part of the Collateral, and ( iv ) use commerc ially reasonable efforts to obtain any necessary consents of Third Parties to the perfection of a security i nterest to CHRP with respect to any Collateral or the exercise of any right hereunder . [COMPANY] hereby authorize s CHRP to file one or more financing or continuation state ments, and amendments thereto, relative to all or a ny part of the Collateral without the signature of NeurogesX. In addition to and notwithstanding the foregoing, N eurogesX hereby irrevocably constitutes and appoints CHRP, w ith full power of substitution, as its true and law ful attorney - in - fact, with full irrevocable power and a uthority in its place and stead and in its name or otherwise, from time to time in CHRP ’s sole discretion, at Neu rogesX ’s sole cost and expense, to take any and all appropriate action and to execute and deliver any a nd all documents and instruments which CHRP may dee m reasonably necessary or advisable to accomplish the purposes of this Agreement and to create and perfe ct, and to continue and preserve, an indefeasible continuing f irst priority security interest, subject to Permitt ed Liens, in any and all of the Collateral in favor of CHRP