definiens: sha ll mean ( i ) all patents and patent applications existing as of the Effective Date that claim the synthesis or composition of matter of a Lead Compound which is a Hit ( and/or any other Hits from the same Screening Program as such Lead Compound ) or a corresponding Derivative Compound, or the method of use thereof, and ( ii ) any divisions, continuatio ns, continuations - in - part, reissues, reexaminations, ex tensions or other governmental actions which extend any of the subject matter of the patent applications or pa tents in ( i ) above, and any substitutions, confirma tions, registrations, revalidations, or additions of any o f the foregoing, in each case, which is owned or co ntrolled, in whole or part, by license, assignment or otherwise by [COMPANY] during the term of this Agreement, and subject to any limitations and prohibitions of such license or sublicense