definiens: means as to either of ALN - TTR02 or ALN - TTRsc, as applicable, a replacement productthat ( a ) [COMPANY] brings forward as a substitute for ALN - TTR02 or ALN - TTRsc, as applicable, pursuant to Section 2.5.3.3;and ( b ) ( i ) in the case of such a replacement product for ALN - TTR02, is [ * * ], ( ii ) in the case of such a replacementproduct for ALN - TTRsc, is [ * * ], ( iii ) in the event that [COMPANY] discontinues the Development of ALN - TTR02 because an [ * * ], then, notwithstanding clause ( b)(i ) above, is any siRNA Product in the Field that [COMPANY] advances into ClinicalStudies ( as evidenced by filing of an IND ) within [ * * ] years after the Effective Date or ( iv ) in the event that both ALN - TTR02 and ALN - TTRsc are discontinued prior to receipt of Regulatory Approval thereof, then, notwithstanding clauses(b)(i ) and ( b)(ii ) above, is any siRNA Product in the Field that [COMPANY] advances into Clinical Studies ( as evidenced byfiling of an IND ) within [ * * ] years after the Effective Date