definiens: ( i ) in respect of Atlantic means efforts and resources commonly used in the biotechnology industry by comp anies at a similar stage of development for products of similar commercial potential to dev elop and commercialize a product owned by such a company or to which it has rights, which product is at a similar stage in its development or product life and is of similar marke t potential to the Product in question and taking into account the patent and other proprietar y position of the product ; and ( ii ) in respect of Isis means efforts and resources commonly used b y biotechnology companies of a similar size to Isis based on market capitalization to deve lop a product owned by such a company or to which it has rights, which product is at a simil ar stage in its development or product life and is of similar market potential to the Product i n question and taking into account the patent and other proprietary position of the product . Prom ptly following the meeting with the FDA to discuss the registration strategy for a pouchiti s indication, Atlantic and Isis will agree on the Development Timeline to be included in Appendix 5 . Atlantic ’s meeting of such Development Timeline in Appendix 5 and Isis ’ provis ion of the Candidate Pool to Atlantic in accordance with the Work Plan will be deemed to be examples of using Commercially Reasonable Efforts ; provided, however, that a failu re to meet such Development Timeline will not be dispositive of a failure to use Commerc ially Reasonable Efforts