definiens: means a Collaboration Program terminated by [COMPANY] u nder thisSection 9.2.1 meeting the following conditions : ( a ) the Collaboration Program is not focused on [ * * * ] o r [ * * * ] ; ( b ) [COMPANY] terminated such Collaboration Program after San ctioned Target stage but prior toGSK ’s exercise of the applicable Option for such Co llaboration Program ; ( c ) at the time of such termination, Isis had initiated Development work past the SanctionedTarget stage for such Collaboration Program and in Developing such Collaboration ProgramIsis spent at least an amount equal to ( i ) $ [ * * * ] plus ( ii ) [ * * * ] percent ( [ * * * ] % ) of the aggregateamount of the [ * * * ] and [ * * * ] paid by [COMPANY] to Isis p ursuant to Section 5.3 and Section 5.5 or5.6, as demonstrated by documentation provided to [COMPANY] ; ( d ) solely with respect to [ * * * ], such terminated Colla boration Program was the last CollaborationProgram focused on [ * * * ] ; and ( e ) solely with respect to the [ * * * ] Program, such term inated Collaboration Program was the last [ * * * ] Program subject to an Option under this Agree ment