Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Cross-Education Of Contralateral Antagonists

Eligibility criteria:
Inclusion Criteria:

          -  young-adult healthy volunteer

          -  male

          -  right hand dominant

        Exclusion Criteria:

          -  a chronic disease such as metabolic/endocrine bone disease (osteoporosis,
             osteomalacia, paget's disease etc)

          -  myopathy

          -  tendinopathy

          -  neurologic disorders (hypoesthesia/anesthesia, epilepsy, paralysis)

          -  dermatologic disease

          -  peripheral vascular disease

          -  joint disease

          -  cardiac pacemaker

          -  noncooperative

          -  professional sportsman

          -  regular sportive activity such as tennis, volleyball

          -  heavy worker
Male
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 45 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: High Intensity Strength Training & Bone Mineral Density in Young Women

Eligibility criteria:
Inclusion Criteria:

          -  Participants include young and healthy women between the ages of 18-30, who have not
             engaged in strength training for the last 6 months.

        Exclusion Criteria:

          -  Subjects will be excluded from the study if they have any condition that preclude them
             from taking part in the exercise testing procedures or the 24 week exercise program or
             if they fail to obtain the required amount of training sessions.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Quantifying and Understanding the Signs and Symptoms of Fever

Eligibility criteria:
-  INCLUSION CRITERIA PHASE I:

        Adult and pediatric medical-surgical patients hospitalized in the Clinical Center, NIH
        admitted to 3NE (oncology/ transplant), 3NW (surgical oncology) and 1NW (pediatrics).

        Oriented to person, time and place at time of interview

        Active fever (body temperature greater than or equal to 38.0 Celsius), treated or
        untreated, within the last 12 hours.

        Willingness to participate in a short interview (15-20 minutes) about their symptoms

        Understands and speaks English

        Age 8 years and older

        INCLUSION CRITERIA FOR STUDY OF FEBRILE ASSESSMENT TOOL:

        Adult (18 years of age or greater) medical-surgical patients hospitalized at the Clinical
        Center and admitted to 3NW.

        Oriented to person, time and place at time of admission

        Willingness to be asked about their symptoms of fever during vital signs assessment

        Understands and speaks English

        INCLUSION CRITERIA PHASE II:

        Inpatients admitted to the Clinical Center

        Age 8 years and older
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 3-year-old girl is brought to the clinic by her parents for assessment of her short stature. Physical examination reveals short limbs and a relatively large head. She has a flat nasal bridge and a small midface. The girl's father exhibits similar physical features; however, her mother looks normal. The genetic testing reveals an autosomal dominant point mutation in the fibroblast growth factor receptor 3 (FGFR3) gene consistent with achondroplasia in both father and the child. The girl has not received any treatment yet, and it is her first visit after immigration to the US. The other mental and developmental examinations are unremarkable.

Patient's own account: I just brought my little 3-year-old girl to the clinic to have her checked up by the doctor. I was worried sick because she was smaller than her classmates. The lovely doctor performed a physical exam and she told me that she has short limbs and a larger head. My girl also has a flat nasal bridge and a small midface. My baby just has the face of her father, unlike me! They performed some genetic testing on my child and my husband and found out that both my husband and her have a mutation of the FGFR3 gene, which led the doctor to diagnose them with dwarfism. My baby never received any treatment and it was our first visit to the doctor since we arrived in the US. The other tests regarding her mental and physical development were perfectly fine.

Clinical trial: Growth Response in Girls With Turner Syndrome

Eligibility criteria:
Inclusion Criteria:

          -  Turner syndrome

          -  If age below 3 years, either body height below - 1 SD (standard deviation) with
             average growth velocity according to chronological age or body height below 0 SD with
             growth velocity below -1 SD according to chronological age

          -  If age above 3 years, body height below - 1 SD with average growth velocity according
             to chronological age

          -  Measured parental height available

          -  Written informed consent
Female
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient's own account: The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Clinical trial: Postural Effects of Being Rotated in a Whole Body Gyroscope

Eligibility criteria:
Inclusion Criteria:

          -  Normal Healthy Adults without a history of vertigo or dizziness

        Exclusion Criteria:

          -  History of dizziness or vertigo
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Clinical and Haematological Phenotypes in Long COVID

Eligibility criteria:
Inclusion Criteria:

          1. Patients post documented SARS-CoV-2 infection displaying symptoms of long Covid

          2. Asymptomatic post documented SARS-CoV-2 infection

          3. All patients will be aged 18 or over

        Exclusion Criteria:

          1. Patients below the age of 18

          2. Patients who have not previously had COVID-19

          3. Any adult deemed to trigger consideration of being a Vulnerable Adult.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency

Eligibility criteria:
Inclusion Criteria:

          -  Chronological age ≥ 3

          -  Chronological age or bone age ≤ 12 for boys and ≤ 11 for girls

          -  Prepubertal at Visit 1

          -  Height SD score of < -2

          -  IGF-1 SD score of < -2

        Exclusion Criteria:

          -  Prior treatment with GH, IGF-1, or other growth-influencing medications

          -  Growth failure associated with other identifiable causes (e.g., syndromes, chromosomal
             abnormality)

          -  Chronic illness such as diabetes, cystic fibrosis, etc.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Fat Graft Myringoplasty With and Without Platelet Rich Plasma (PRP) for Treating Smaller Tympanic Membrane Perforations

Eligibility criteria:
Inclusion Criteria:

          -  Tympanic membrane perforation measuring <50% of the area of the membrane

          -  Perforation present for at least 6 months (based on history or direct observation)

          -  All edges of perforation are visible

        Exclusion Criteria:

          -  Active ear infection at the time of the procedure

          -  cholesteatoma present

          -  Patients on immunosuppressive therapy (including oral steroids) or chemotherapy

          -  Patients with previous failed attempt at perforation repair
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient's own account: I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Clinical trial: Emergency Department Smoking Cessation Study

Eligibility criteria:
Inclusion Criteria:

          -  19 years of age or older

          -  stable (vital signs within normal limits not requiring immediate physician
             intervention)

          -  used a tobacco product in the last 30 days

          -  presenting to the Vancouver General Hospital Emergency Department

          -  can provide informed consent in English

        Exclusion Criteria:

          -  cannot provide informed consent

          -  sexual assault patients

          -  not a resident of British Columbia

          -  unable to provide telephone number of email address for follow-up
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Retrieval Versus Mid-luteal Endometrial Scratching (ES) for Intra Cytoplasmic Sperm Injection (ICSI)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with at least one previous failed ICSI cycles, Good responders in the
             previous ICSI cycle and Less than or equal to 35 years

        Exclusion Criteria:. We excluded patients with; Presence of intramural fibroid distorting
        the endometrial cavity/sub mucous myoma/a Sherman's syndrome, Presence of son graphically
        detected hydrosalpinx, Patient age more than 35 years
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 35 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Ventrointermediate Nucleus (VIM DBS) and Working Memory

Eligibility criteria:
Inclusion Criteria:

        ET PATIENTS:

          -  Clinical diagnosis of essential tremor affecting the upper extremities.

          -  Previous unilateral or bilateral DBS of the VIM

          -  Ages 40 -70

          -  A useable pre-surgical MR scan

        CONTROLS:

          -  Spouse or acquaintance of enrolled patient participant

          -  Ages 40 - 70

        Exclusion Criteria:

        ET PATIENTS:

          -  Clinical evidence of other neurological conditions

          -  Significant psychiatric condition

        CONTROLS:

          -  Clinical evidence of other neurological conditions

          -  Significant psychiatric condition
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment