Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Effects of Teriparatide (PTH) on Bone in Men and Women With Osteoporosis

Eligibility criteria:
Inclusion Criteria:

          -  History of fragility fracture OR

          -  High risk for fractures OR

          -  Very low BMD (T-score ≤ -2.5) OR

          -  Failed or intolerant to bisphosphonates

          -  Baseline serum levels of calcium, urate, ALP, PTH, creatinine and 25- hydroxyvitamin D
             [25(OH)D] must be within acceptable normal limits

          -  Ability to obtain teriparatide (not supplied by study sponsor)

        Exclusion Criteria:

          -  History of skeletal irradiation

          -  Those at increased risk for osteosarcoma

          -  Diagnosis of Paget's disease

          -  History of primary hyperparathyroidism

          -  Significant renal impairment

          -  Vitamin D deficiency

          -  On steroids or have other causes of secondary osteoporosis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Evaluation of the Role of Follicular Sensitivity Index in the Prediction of IVF/ICSI Outcome

Eligibility criteria:
Inclusion Criteria:

          -  IVF/ICSI

        Exclusion Criteria:

          -  Missing data

          -  Cancelled cycles.

          -  Polycystic ovarian syndrome.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 42 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Reducing HIV Risk in Urban Women: Soap Opera Videos on Video-Capable Cell Phones

Eligibility criteria:
Inclusion Criteria:

          -  Women 18-29 years old

          -  Unprotected vaginal or anal sex with at least one man that they perceive as engaging
             in risky behavior OR

          -  Unprotected vaginal or anal sex with more than 1 man regardless of perceived partner
             risk

          -  Can understand written and spoken English

        Exclusion Criteria:

          -  Women younger than 18 years old

          -  Women older than 29 years old

          -  Cannot understand written or spoken English

          -  Previously participated in the study
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 29 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: A Smart Physical Examination System for the Health Management in Elderly

Eligibility criteria:
Inclusion Criteria:

        1.55-85 years old 2.people who can do movement by 3.people who can walk >10m independently.

        Exclusion Criteria:

          1. people who implant cardiac rhythm, have cardiac arrhythmia,tumor,infection,or any
             other internal disease.

          2. people who have visual disturbance (Corrected vision<4.0 or any ophthalmic diseases
             caused bad eyesight),hearing loss,movement disorder.

          3. people who can't stand stably.

          4. people who can't fill out a questionnaire independently.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 55 Years old.
Subject must be at most 85 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Efficacy of Intra-articular Injection of Human Amniotic Suspension Allograft and Platelet-rich Plasma in the Treatment of Knee Osteoarthritis.

Eligibility criteria:
Inclusion Criteria:

          -  Age between 20 and 80 years

          -  Ability to provide informed consent

          -  Unilateral or bilateral knee VAS pain score ≥ 4 of 10 (worst possible pain) for more
             than 4 months

          -  Diagnosis of OA Kellgren-Lawrence I-III by radiography (triple-film of bilateral lower
             limb, standard knee anterior-posterior view in full extension, lateral view in
             30-degrees flexion, and 45°Merchant views)

          -  No prior PRP injection of knee

          -  No prior surgical procedure of the participating knee

          -  BMI<40 kg/m2

        Exclusion Criteria:

          -  Lawrence stage IV

          -  Major axial deviation (varus> 5°, valgus > 5°)

          -  Any concomitant symptomatic knee disorder (i.e. ligamentous/ meniscal injury)

          -  Systemic inflammatory arthropathy

          -  Hematologic diseases

          -  Severe cardiovascular disease

          -  Neurological disorders

          -  Active infection

          -  Immuno-compromised

          -  Therapy with anticoagulants or antiaggregants

          -  Use of NSAIDs and/or chondroprotective supplements, such as glucosamines and
             chondroitin sulfates, within 7 days prior to trial

          -  Recent intra-articular injection of corticosteroids (within 30 days)

          -  Prior treatment with HA in past 6 monthsHb< 11 g/dL

          -  Platelet count < 150,000/mm3
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Cricopharyngeal Dysfunction and Esophageal Diverticulum

Eligibility criteria:
Inclusion Criteria:

          -  Patients with a diagnosis of cervical esophageal diverticulum, with Zenker's as most
             common, or CP bar (with diagnosis of early Zenker) as indicated on an esophagram who
             the participating institutions enroll regardless of surgical management and future
             treatments. Patients undergoing open transcervical or endoscopic approach in which a
             laser or stapler is used to divide the common wall between the diverticulum and
             esophagus, or who are not surgical candidates but agree to follow-up.

        Exclusion Criteria:

          -  Patients who undergo division of the common wall between the diverticulum and
             esophagus using flexible endoscopy will not be included in the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient's own account: I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Clinical trial: Long-Working Distance OCT for Children

Eligibility criteria:
Inclusion Criteria:

          -  Minor or adult undergoing eye examination at Duke Eye Center

          -  Adults with normal eye health enrolled as controls

        Exclusion Criteria:

          -  Have any ocular disease that restricts the ability to perform OCT scanning

          -  Minor under the age of 6 months
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 6 Months old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: A Prospective Randomized Comparison Trial on the Use of Mifepristone With Sublingual or Buccal Misoprostol for Medical Abortions of Less Than 9 Weeks Gestation

Eligibility criteria:
Inclusion Criteria:

          -  good general health

          -  older than the age of legal consent (i.e. >18 years old)

          -  requesting medical abortion and eligible for abortion

          -  on Day 1 of the study (day of mifepristone administration) the duration of pregnancy
             not more than 63 days as confirmed by pelvic ultrasound examination

          -  intrauterine pregnancy (intrauterine amniotic sac seen in US)

          -  willing to use other than hormonal or intra-uterine contraception until the first
             menses after termination of pregnancy

          -  if treatment fails she agrees to termination of pregnancy with the surgical method

          -  willing and able to participate after the study has been explained

          -  haemoglobin higher than 10g/L

        Exclusion Criteria:

          -  a history or evidence of adrenal pathology, steroid-dependent cancer, porphyria,
             diastolic pressure over 95mm Hg, bronchial asthma, arterial hypotension.

          -  a history or evidence of thrombo-embolism, severe or recurrent liver disease or
             pruritus of pregnancy

          -  the regular use of prescription drugs before admission to the study

          -  the presence of an IUCD in utero

          -  breast-feeding

          -  multiple pregnancies

          -  heavy smokers
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Short-term Impact of Cyplexinol® on Self-reported Joint Pain

Eligibility criteria:
Inclusion Criteria:

          -  body mass index (BMI) between 18-29.9 kg/m2 (not obese)

          -  no consumption of alcohol-containing beverages within 48 hours of testing

          -  experiencing self-reported joint pain with a minimum pain rating of 3/10 for at least
             the past 30 days

          -  engaged in structured exercise 2 or more days per week for the past 6 months or longer

          -  a negative verbal pre-study drug screen (alcohol abuse, amphetamines, benzodiazepines,
             cocaine, opioids, phencyclidine, barbiturates, cotinine), no history of use of illicit
             drugs or other substances of abuse within 12 months of the screening visit

        Exclusion Criteria:

          -  pregnant

          -  tobacco user

          -  active infection or illness of any kind

          -  rheumatic or osteoarthritic diagnosis

          -  Using anti-inflammatory medicines, pain medications, or dietary supplements (or not
             willing to cease for one-month prior to participation and throughout study)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air

Eligibility criteria:
Inclusion Criteria:

          -  Male and female

          -  Ages >/= 18 years

          -  Diagnosed with one or more lung diseases

          -  Referred for sputum induction to the Pulmonary Laboratory in the Tel-Aviv Sourasky
             Medical Center
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment