Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Vital Sign Comparison Between Lifelight and Standard of Care - Development

Eligibility criteria:
Inclusion Criteria:

          -  I1. Sufficiently conversant in the English language to satisfy I3.

          -  I2. Able and willing to comply with all study requirements.

          -  I3. Able and willing to provide written informed consent to participate (including by
             parent or legal guardian if under 16 years old).

        Exclusion Criteria:

          -  There are no exclusion criteria.
No condition on gender to be admitted to the trial.

Subject must be at least 3 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Investigations on Differences in Atorvastatin Metabolites Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity

Eligibility criteria:
Inclusion Criteria:

          -  Suspected atorvastatin induced muscle adverse events.

          -  Signed informed consent.

          -  18 years of age or older.

          -  Able to donate blood samples.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Clinical Testing of New MR Pulse Sequences

Eligibility criteria:
Inclusion Criteria:

          -  Healthy volunteers

          -  Patients undergoing clinical indicated MRI

        Exclusion Criteria:

          -  Patients with contraindication for MRI

          -  Pregnant women will be excluded from this study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient's own account: I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Clinical trial: The Effect of Tart Cherry Juice on Risk of Gout Attacks

Eligibility criteria:
Inclusion Criteria:

          -  existing diagnosis of gout

          -  have experienced at least one gout flare in the previous 12 months

          -  able and willing to participate in the study and provide written informed consent

        Exclusion Criteria:

          -  frequently consume cherries or cherry products e.g. cherry supplements and juice (more
             than once a week)

          -  severe renal impairment (estimated glomerular filtration rate of <30ml/min)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: Observational Prospective Analysis of Biological Characteristics of Mesothelioma Patients

Eligibility criteria:
Inclusion Criteria:

          -  Malignant pleural mesothelioma patients

          -  Availability of plural effusion and frozen and paraffin-embedded tumor specimens.

        Exclusion Criteria:

          -  Unavailability of plural effusion and frozen and paraffin-embedded tumor specimens.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis

Eligibility criteria:
Inclusion Criteria:

          1. Cases of lateral epicondylitis.

          2. Men and women above fifteen years of age.

        Exclusion Criteria:

          1. Patients receiving steroid injections within three months before blood injection.

          2. A history of substantial trauma.

          3. Previously treated by surgery for lateral epicondylitis.

          4. Other causes of elbow pain such as osteochondritis dessecans of capitellum, lateral
             compartment arthrosis, varus instability, radial head arthritis, posterior
             interosseous nerve syndrome, cervical disc syndrome, synovitis of radiohumeral joint,
             cervical radiculopathy, fibromyalgia, osteoarthritis of elbow, carpel tunnel syndrome.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 15 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Embryoscopic Evacuation for Induced Abortion

Eligibility criteria:
Inclusion Criteria:

          1. Women between the ages of 21 years - 45 years inclusive.

          2. Referred for dilatation and curettage for induced abortion

          3. Confirmed intrauterine pregnancy with gestational age of up to 9 weeks

          4. At least one previous normal vaginal delivery with a healthy child

          5. Patients are able to provide written consent

          6. Patients with no underlying medical conditions

        Exclusion Criteria:

          1. Inability to consent due to cognitive or language barrier

          2. Significant uterine bleeding, fever or incomplete abortion

          3. Previous cesarean section

          4. Sub-chorionic hematoma, Malformed uterus or Submucosal fibroids

          5. Any underlying medical condition requiring medical treatment

          6. Documented failed hysteroscopy prior to the current referral
Female
Accepts Healthy Volunteers
Subject must be at least 21 Years old.
Subject must be at most 45 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient's own account: I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Clinical trial: Quality of Life in Neuromuscular Disease

Eligibility criteria:
Inclusion Criteria:

          -  Patient with neuromuscular disease

        Exclusion Criteria:

          -  <18 yo
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Clinical Cohort Study on the Endocrinology and Vaginal Microbiome of the Luteal Phase in Assisted Reproduction

Eligibility criteria:
Inclusion Criteria:

          1. Patients aged 18 to 45 years

          2. Transfer of cryopreserved embryos

        Exclusion Criteria:

          1. Fresh IVF/ICSI embryo transfer cycle

          2. Evidence for ovulation on ultrasound previous to embryo transfer confirmed by a
             follicle ≥14mm or by a progesterone ≥1.0 µg/l in programmed cycles

          3. Uterus malformations, endometrial abnormalities (on ultrasound or diagnosed by
             previous hysteroscopy)
Female

Subject must be at least 18 Years old.
Subject must be at most 45 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient's own account: I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Clinical trial: Role of Nutritional Support in Idiopathic Male Infertility

Eligibility criteria:
Inclusion Criteria:

          1. Informed consent form signed;

          2. Age: 21-50;

          3. Idiopathic male infertility;

          4. Idiopathic oligo- and/or astheno- and/or teratozoospermia;

          5. Stated availability throughout the study period and a mobile phone

        Exclusion Criteria:

          1. Allergy to any component of the dietary supplement;

          2. Known genetic, anatomical, endocrine, inflammatory or traumatic testicular cause of
             male infertility;

          3. Known genetic, anatomical, endocrine, inflammatory or traumatic testicular cause of
             female infertility;

          4. Inflammatory bowel disease;

          5. Known moderate to severe disease of any systems;

          6. Known or suspected sexually transmitted diseases;

          7. Alcohol or drug addiction of any couple counterpart as suspected by investigator;

          8. Difficulty to comprehend study requirements as judged by investigator;

          9. Use of any investigational product within the previous 3 months before entering the
             study;

         10. Use of any drugs that stimulate or suppress spermatogenesis within previous 3 months
Male
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient's own account: The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Clinical trial: Cognitive Screening Of Patients With Hearing Loss

Eligibility criteria:
Inclusion Criteria:

          -  - Age 50 - 90

          -  Measurable hearing loss

          -  Sufficient knowledge of german

          -  Ability to consent

        Exclusion Criteria:

          -  Age < 50 or >90

          -  No measurable hearing loss

          -  Present or past alcohol or drug abuse

          -  Clinically relevant depressive symptoms

          -  lnability to consent
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Contradiction