Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: The Effect of Preoperative Hemotologic Markers on Postoperative Long-term and Short-term Outcomes for Laparoscopic Gastrectomy

Eligibility criteria:
Inclusion Criteria:

          -  Age from 18 to 75 years

          -  Primary lower third gastric adenocarcinoma (papillary, tubular, mucinous, signet ring
             cell, or poorly differentiated) confirmed pathologically by endoscopic biopsy

          -  cT2-4a, N0-3, M0 at preoperative evaluation according to the American Joint Committee
             on Cancer (AJCC) Cancer Staging Manual Seventh Edition

          -  No distant metastasis is observed. And the spleen, pancreas or other adjacent organs
             are not involved by the tumor.

          -  Performance status of 0 or 1 on Eastern Cooperative Oncology Group scale (ECOG)

          -  American Society of Anesthesiology score (ASA) class I, II, or III

          -  Written informed consent

        Exclusion Criteria:

          -  Women during pregnancy or breast-feeding

          -  Severe mental disorder

          -  History of previous upper abdominal surgery (except laparoscopic cholecystectomy)

          -  History of previous gastrectomy, endoscopic mucosal resection or endoscopic submucosal
             dissection

          -  Enlarged or bulky regional lymph node envelop important vessels

          -  History of other malignant disease within past five years

          -  History of previous neoadjuvant chemotherapy or radiotherapy

          -  History of unstable angina or myocardial infarction within past six months

          -  History of cerebrovascular accident within past six months

          -  History of continuous systematic administration of corticosteroids within one month

          -  Requirement of simultaneous surgery for other disease

          -  Emergency surgery due to complication (bleeding, obstruction or perforation) caused by
             gastric cancer

          -  FEV1<50% of predicted values
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Adjuvant PIPAC in Gastric Cancer Patients

Eligibility criteria:
Inclusion Criteria:

          -  Patients with high-risk GAC defined as: Diffuse cancer (signet ring cells predominant)
             or clinical stage: cTany + cN2-3 or cT3-T4 + cNany or GAC patients with preoperative
             positive peritoneal cytology submitted to laparoscopic gastrectomy (+/- neoadjuvant
             treatment).

          -  Age 18 or above

          -  Written informed consent

          -  Women must be postmenopausal or use adequate contraception with a negative pregnancy
             test at inclusion.

        Exclusion Criteria:

          -  Previous allergic reaction to cisplatin, doxorubicin or other platinum containing
             compounds.

          -  Renal impairment, defined as GFR < 40 ml/min (Cockcroft-Gault Equation).

          -  Myocardial insufficiency, defined as NYHA class 3-4.

          -  Impaired liver function defined as bilirubin ≥ 1.5 x UNL (upper normal limit).

          -  Inadequate haematological function defined as absolute neutrophil count (ANC) ≤ 1.5 x
             10^9/l and platelets ≤ 100 x 10^9/l.

          -  Any other condition or therapy, which in the investigator's opinion may pose a risk to
             the patient or interfere with the study objectives.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient's own account: I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Clinical trial: The Percentage of Cases of Acute Treatment With Allopurinol in Gout Patients

Eligibility criteria:
Inclusion Criteria:

          -  Gout patients

        Exclusion Criteria:

          -  Pregnant women

          -  Chronic renal failure

          -  Patients with Allopurinal hypersensitivity
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Evaluation of Physical and Cognitive Performance After Simulated Road March Combines Physical and Cognitive Load Using a Virtual Reality Environment

Eligibility criteria:
Inclusion Criteria:

          -  aged 18-30

          -  healthy civilians volunteers

          -  with no background illnesses

          -  with history of combat unit service in the IDF.

          -  fit to perform 10 Km moderate march while carrying load.

        Exclusion Criteria:

          -  The existence or suspicion of existing cardiac or respiratory disease.

          -  Hypertension.

          -  Diabetes.

          -  Any muscles or skeleton condition.

          -  Any hormonal disease or any other chronic illness that may inhibit participation in
             the experiment.

          -  Infectious disease 3 days prior to the experiment.
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Practice and Patient Compliance on the PPI (Proton Pump Inhibitors) Treatment of Gastroesophageal Reflux in South Korea

Eligibility criteria:
Inclusion Criteria:

          -  Patients complaining about heartburn or acid regurgitation, the typical GERD symptoms,
             more than once a week

          -  After a full explanation about the observational study, patients who fully understand
             it and sign a written consent form

        Exclusion Criteria:

          -  Patients who took rabeprazole sodium within the last four weeks

          -  Patients who are hypersensitive to the active ingredient of rabeprazole sodium or
             benzimidazole

          -  Patient with other digestive tract diseases other than GERD (gastrointestinal cancer,
             liver disease, pancreatic disease, peptic ulcer, inflammatory digestive tract diseases
             [in case of ulcer, however, scars from healed ulcer may be included])

          -  Patients with other severe accompanying diseases including renal impairment,
             cerebrovascular disease, cardiovascular disease and severe respiratory disease

          -  Patients who must constantly take Proton Pump Inhibitors other than rabeprazole sodium
             during study period

          -  Pregnant or lactating women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient's own account: I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Clinical trial: Treating Amyotrophic Lateral Sclerosis (ALS) With R(+) Pramipexole Dihydrochloride Monohydrate at 60 mg/Day

Eligibility criteria:
Inclusion Criteria:

          -  Definite diagnosis of ALS

        Exclusion Criteria:

          -  No prior participation in R(+)PPX clinical studies
No condition on gender to be admitted to the trial.

Subject must be at least 30 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Lowering Blood Pressure by Changing Lifestyle

Eligibility criteria:
Inclusion Criteria:

          -  Participants with clinic blood pressure more than or equal to 130/80 mm Hg who are not
             taking medication

          -  Participants with controlled blood pressure defined as < 130/80 using
             anti-hypertensive medication for a minimum of six weeks.

          -  Participants live in Banshgram Union only

        Exclusion Criteria:

          -  Aged > 75 years of age

          -  Pregnant women

          -  People who have advanced CVDs or are any serious condition that restricts their
             participation in the study

          -  Participants will be withdrawn from the study if they are unwilling to continue their
             participation and withdraw their consent, or any women participants who become
             pregnant during the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 30 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)

Eligibility criteria:
Inclusion Criteria:

          -  Subjects must have reported history of heartburn symptoms whilst on lansoprazole 30 mg
             twice daily during the 30 days prior to screening.

          -  Subjects must have a minimal cumulative heartburn score of at least 4 for a minimum of
             14 days, where zero = none, one = mild, two = moderate, three = severe.

        Exclusion Criteria:

          -  subjects history of esophageal ulcers, esophageal strictures, esophageal neoplasms,
             gastric or duodenal ulcers, or any other significant gastric or esophageal pathology
             judged to be clinically significant by the investigator.

          -  Subjects with persistent heartburn symptoms while on lansoprazole 30 mg twice daily
             for a period of > 6 months

          -  Subjects with a history of severe hepatic insufficiency (specifically, Childs-Pugh
             Class C liver disease) that may adversely affect the metabolism abd pharmacokinetics
             of esomeprazole and/or lansoprazole.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: The Effect of Vitamin D on in Vitro Fertilization Outcome

Eligibility criteria:
Inclusion Criteria:

          1. age between 21-40 years old

          2. basal FSH hormone level less than 10 mIU/mL

          3. the first cycle of IVF treatment with standard long protocol

          4. both ovarian present and normal uterus.

        Exclusion Criteria:

          1. PGD cycles

          2. Gametes donation cycles

          3. Anyone that does not meet the inclusion criteria
Female
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Genosvid Diagnostic Test for Early Detection of COVID-19

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed with COVID-19, non COVID-19, and suspected COVID-19 infection,
             based on the results of anamnesis, physical examination, laboratory, X-rays and rapid
             tests.

          -  Able to produce samples for RT-PCR examination.

          -  Agree to participate (sign informed consent). For children, informed consent are
             obtained from the parents. For adolescent patients, accent consent is asked.

          -  Patients who do not need oxygen therapy supplementation in the form of mask-type or
             ventilator. Patients who use oxygen supplementation with nasal cannula are still
             included as study participants.

        Exclusion Criteria:

          -  Unable to breath deeply due to difficulty breathing due to complications of COVID-19
             or other diseases

          -  The quality of the breath do not meet the standard interpretation of the instrument
             sensor curve (breath sampel is declared invalid).
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.


Eligibility (NLI label): Contradiction