Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: A Database Study to Estimate the Risk of Multiple Sclerosis Following Vaccination With Arepanrix™ in Manitoba, Canada

Eligibility criteria:
Inclusion Criteria:

          -  The entire population of Manitoba is considered for inclusion.

        Exclusion Criteria:

          -  Individuals less than or equal to 6 months of age;

          -  Having less than one year of insurance coverage before the enrolment period;

          -  Not registered with MH during the enrolment period;

          -  Physician or hospitalization records indicating a diagnosis of any demyelinating
             condition between 1971 (earliest year for which information is available) and the
             index date.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 6 Months old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 2-year-old boy is brought to the office by his parents due to a rash that started 1 week ago.  A similar red, itchy rash on the cheeks, trunk, and arms has occurred intermittently since infancy.  The patient has had a few upper respiratory infections but no major illnesses.  Vaccinations are up to date, and he takes no medications. He is on a balanced diet, and he is healthy in appearance.  Vital signs and milestone examination are within normal limits.  Similar findings are observed on the cheeks and proximal upper extremities.  The diaper area is clear, and no mucosal lesions are present.

Patient's own account: I just brought my two-year-old son to the doctor's office because he had a rash for like one week. His rash was on the cheeks, the trunk, and his arms. He already had this before, and it keeps coming back from time to time to time. In the past, he had some respiratory infections but he has never been this sick. His vaccinations are up to date, and he doesn't take any medication. He's healthy with a nice diet. The doctor told me his vitals and milestone examinations were normal. The doctor also said there was a rash around the cheek and the upper part of his arms. The diaper area is okay, and there are no lesions.

Clinical trial: Evaluation of Topical B12 for the Treatment of Childhood Atopic Dermatitis

Eligibility criteria:
Inclusion Criteria:

          -  children presenting to the Center for Family Medicine or Regional Pediatrics between
             the ages of 6 months and 18 years old with atopic dermatitis

        Exclusion Criteria:

          -  unwillingness of parent to consent to study protocol, pregnancy or lactation, eczema
             with superinfection present, known history of allergy to Vitamin B12 or components of
             the base cream, topical treatment with corticosteroids in the 4 weeks prior to
             enrollment
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 6 Months old.
Subject must be at most 18 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Audiology Visits After Screening for Hearing Loss: An RCT

Eligibility criteria:
Inclusion Criteria:

        Hearing impaired

        Exclusion Criteria:

        Not Hearing Impaired
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Study of Surgical Mesh for Inguinal Hernia Repair

Eligibility criteria:
Inclusion Criteria:

          -  male ≥19 years old

          -  symptomatic and palpable inguinal hernia

          -  candidate for unilateral, primary, open inguinal hernia repair using the Lichtenstein
             technique

          -  will comply with required follow-up study visits

          -  willing and able to provide written informed consent

        Exclusion Criteria:

          -  BMI ≥35

          -  life expectancy of <3 years

          -  strangulated hernia

          -  urologic disorder and/or previous urologic surgery in the testicular area (with the
             exception of prostate surgery)

          -  active abdominal surgical condition such as bowel obstruction or perforation

          -  local or systemic infection or peritonitis

          -  known disease that impairs wound healing

          -  anti-platelet therapy (other than aspirin) for >7 days preceding the surgical
             procedure

          -  previous ipsilateral groin incision

          -  receiving immunosuppressive therapy and/or has undergone radiation therapy to the
             affected groin area

          -  uncontrolled insulin-dependent diabetic with Hgb1Ac greater than 8

          -  advanced cirrhosis with Child-Turcott Class of C or higher

          -  severe COPD requiring home oxygen

          -  diagnosed with chronic pain syndrome or is undergoing treatment for pain management

          -  candidate for another major surgical procedure with the inguinal hernia repair

          -  enrolled in another investigational study that may confound the results of this study

          -  known drug abuser

          -  on anti-psychotic medications

          -  Worker's Compensation case
Male
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: Investigating Signal Change in Malignant and Non-malignant Pleural Effusions and asCitic Fluid Using fTiR Analysis

Eligibility criteria:
Inclusion Criteria:

          -  Aged ≥18 years.

          -  A confirmed, clinician made diagnosis of the following (supported by standard accepted
             diagnostic criteria):

          -  Malignant pleural effusion: confirmed cancer

          -  lung cancer

          -  mesothelioma

          -  or metastatic cancer

          -  Non-malignant pleural effusion: effusion confirmed to be caused by alternative
             diagnosis

          -  Malignant ascites: confirmed cancer

          -  Non-malignant ascites: ascites confirmed to be caused by alternative diagnosis

          -  Willing and able to give informed consent for participation in the study.

        Exclusion Criteria:

          -  Unable to comprehend the study

          -  Unable to provide informed consent
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Remote Manipulation of a Capsule Endoscope

Eligibility criteria:
Inclusion Criteria:

          -  Asymptomatic adult volunteer with previously determined normal esophagus and stomach
             who understands the risks of the procedure.

        Exclusion Criteria:

          -  Known strictures in the intestine,

          -  Crohn's disease,

          -  Swallowing difficulty,

          -  Age less than 21,

          -  Age over 75 or have a pacemaker,

          -  Presence of implanted metal devices,

          -  Presence of esophageal or bowel disease or conditions that may preclude study
             participation as a matter of clinical judgment.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient's own account: I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Clinical trial: Interferon-alpha Treatment of Chronic Cough in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Eligibility criteria:
Inclusion Criteria:

        For all patients

          -  history of clinically significant chronic cough for > 3 months

          -  For COPD patients

          -  >40 years of age

          -  20-pack-year history of smoking

          -  GOLD classification of Stage 1 or higher

          -  For IPF patients

          -  > 50 years of age

          -  history of unexplained dyspnea on exertion of > 3 months

          -  exhibits coughing and bilateral, basilar, inspiratory crackles on physical exam

          -  presents as being in a stable phase of IPF

          -  lung biopsy or HRCT indicative of IPF

        Exclusion Criteria:

          -  ACE inhibitor use

          -  GERD

          -  current cancer or history of lung cancer

          -  non-ambulatory

          -  hospitalized in the previous 12 months for heart failure
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Safety and Efficacy of Lansoprazole in Patients With Reflux Disease

Eligibility criteria:
Inclusion Criteria:

          -  Had Gastro Esophageal Reflux disease with or without oesophagitis.

          -  Had a history of heartburn at least for 5 days per week during the past 6 months or
             was receiving long-term treatment with a proton pump inhibitor and during two weeks
             (without proton pump inhibitor treatment) prior to enrolment.

        Exclusion Criteria:

          -  History of surgery of stomach or oesophagus.

          -  Gastric ulcer (can be included after healing of gastric ulcer).

          -  Duodenal ulcer (can be included after healing of duodenal ulcer).

          -  Bleeding (melena, hematemesis).

          -  Severe concomitant disease (cancer, cardiovascular, renal, hepatic diseases).

          -  Barrett oesophagus with dysplasia.

          -  Complicated esophagitis (oesophageal strictures or ulcers).

          -  Treatment with proton pump inhibitor or Histamine receptor 2 (H2)antagonists within
             the previous two weeks.

          -  Pregnancy, wish to become pregnant, breast feeding.

          -  Treatment with non steroidal anti-inflammatory drugs, treatment with acetylsalicylic
             acid (aspirin) > 100 mg/day.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children

Eligibility criteria:
Inclusion Criteria:

          -  Children has completed all visits and therapy in previous phase IV study;

          -  Investigators evaluate subjects could continue growth hormone therapy;

          -  Subjects is willing and able to cooperate to complete scheduled visits, treatment
             plans and laboratory tests and other procedures, to sign informed consent.

        Exclusion Criteria:

          -  Children with epiphyseal closure;

          -  Children is near the adule final height, that is, growth rate≤ 2 cm / year or bone age
             ≥ 14 years old for girls, bone age ≥ 16 years old for boys;

          -  Dysfunction of liver and kidney (ALT> 2 times the upper limit of normal, Cr> upper
             limit of normal);

          -  Patients with known hypersensitivity to PEG-Somatropin or Somatropin or any other
             components of the study product;

          -  Patients with severe cardiopulmonary or hematological diseases, a current or past
             history of malignant tumors, immunodeficiency diseases, or mental diseases;

          -  Patients with diabetics;

          -  Patients with congenital bone dysplasia or scoliosis;

          -  Patients took drugs that would influence the efficacy and safety of PEG-Somatropin
             after phase IV study and before screening for this extension study;

          -  Other conditions in which the investigator preclude enrollment into the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 42 Months old.
Subject must be at most 15 Years

Eligibility (NLI label): Contradiction