Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: Comparing Injection Treatments for Tennis Elbow

Eligibility criteria:
Inclusion Criteria:

        Invitations to participate in the study will be extended to male and female patients, 18
        years and above, referred to the Orthopaedic Departments who receive a diagnosis of Lateral
        Epicondyle Tendinosis (with or without degenerative changes) with symptoms present for > 3
        months, whose symptoms and clinical evaluation warrant the prescription of a peri-tendinous
        injection to relieve symptoms and who are competent to give informed consent.

        Exclusion Criteria:

          -  Absence of tenderness at the lateral epicondyle.

          -  Congenital or traumatic bio-mechanical deformities of Elbow complex.

          -  Previous Corticosteroidal, Local Anaesthetic, PRP or Hyaluronic Acid injections to
             target elbow within the last three months.

          -  Known hypersensitivity to PRP, Hyaluronic acid or any excipients associated with any
             of the prescribed injections.

          -  Known contraindication to any treatments constituting normal/appropriate therapy in
             the view of the Consulting clinician including local infection

          -  Ipsilateral arm pathology severe enough to cause confusion of localised pain
             perception.

          -  Pregnant or lactating women

          -  Pain score less than 4/10

          -  Patients commenced on medication for the treatment of anxiety or depression within the
             last 6 weeks

          -  Previous involved in research in last 12 months

          -  Any progressive, degenerative neuromuscular disorder
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction