Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Vital Signs Patch Early Feasibility and Usability Study

Eligibility criteria:
Inclusion Criteria:

          -  Adult male and female in-patients with vital signs considered 'stable' by clinical
             caregivers.

        Exclusion Criteria:

          -  Pediatric patients

          -  Female patients who are pregnant

          -  Patients with internal or external defibrillators

          -  Patients who have undergone surgery and still have a fresh incision on the chest.

          -  Patients with skin damage on the chest such as burns, irritation, infections, wounds,
             etc.

          -  Patients in the Critical Care Unit (CCU)

          -  Patients who otherwise satisfy any of the contraindications associated with the VSP
             system.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: COVID-19 Antibody Plasma Research Study in Hospitalized Patients

Eligibility criteria:
Inclusion Criteria:

          1. Age at least 18 years

          2. Ability and willingness of participant or Legally Authorized Representative (LAR) to
             give written informed consent.

          3. Laboratory confirmed diagnosis of infection with SARS-CoV-2 by PCR

          4. Hospitalized for COVID-19 with one or more respiratory or gastrointestinal (GI)
             symptoms:

               -  COVID-19 associated respiratory symptoms include but are not limited to: cough,
                  shortness of breath, difficulty breathing, or sore throat

               -  COVID-19 associated GI symptoms include but are not limited to: loss of taste,
                  loss of sense of smell, diarrhea, nausea, or vomiting,

        Note: Respiratory and GI symptoms other than those listed above, must be noted as
        acceptable and signed by study PI or designee.

        Exclusion Criteria:

          1. Receipt of pooled immunoglobulin in past 30 days

          2. Current or prior enrollment in a SARS-CoV-2 antibody or T-cell therapeutic study.

             Note: Patients enrolled on other randomized controlled trials of pharmaceutical and/or
             non-pharmaceutical interventions for COVID and meeting eligibility criteria will not
             be excluded, as determined by study PI (or designee) on a case-by-case basis and as
             allowed by eligibility criteria of the other trials.

          3. Contraindication to transfusion or history of prior reactions to transfusion blood
             products. This may include religious or cultural objections to receiving blood
             products and transfusions.

          4. ABO-compatible titered plasma is not available

          5. > 10 days from noted COVID-related subjective or objective fever at randomization.
             Patients without subjective or objective fever, > 10 days from symptom onset as
             determined by study PI.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient's own account: I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Clinical trial: Diagnostic Study of Temporal Arteritis

Eligibility criteria:
Inclusion Criteria:

          -  Patients suspected of temporal arteritis and referred by their physicians to biopsy of
             a temporal artery.

        Exclusion Criteria:

          -  Pregnancy; age > 80 or < 18; unable to answer study questions
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Study of Meloxicam Capsules in Subjects With Osteoarthritis of the Knee or Hip

Eligibility criteria:
Inclusion Criteria:

          -  Is male or female ≥ 40 years of age

          -  If a participant in the previous MEL3-12-02 study, completed the study and did not
             discontinue for lack of efficacy or safety

          -  Has a diagnosis of OA of the hip or knee with ongoing knee and/or articular hip pain

          -  Chronic user of nonsteroidal anti-inflammatory drugs (NSAIDs) and/or acetaminophen for
             OA pain

          -  If female and of childbearing potential, is nonlactating and nonpregnant

        Exclusion Criteria:

          -  History of allergic reaction or clinically significant intolerance to acetaminophen,
             aspirin, or any NSAIDs, including meloxicam

          -  Requires continuous use of opioid or opioid combination products to control OA pain of
             the knee or hip

          -  Clinically significant unstable cardiac, respiratory, neurological, immunological,
             hematological, or renal disease

          -  Significant difficulties swallowing capsules or unable to tolerate oral medication

          -  Has received any investigational drug (except Meloxicam SoluMatrix Capsules), device,
             or therapy within 30 days before Screening
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient's own account: The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Clinical trial: OTO-313 in Subjects With Subjective Tinnitus

Eligibility criteria:
Inclusion Criteria:

          -  Subject has subjective unilateral tinnitus and is consistently aware of their tinnitus
             throughout much of the waking day.

          -  Subject is able to use the electronic diary to complete their daily tinnitus ratings

          -  Subject's tinnitus is likely of cochlear origin, e.g., associated with sensorineural
             hearing loss; acute hearing loss from noise trauma, barotrauma, or traumatic cochlear
             injury (acute acoustic trauma, blast trauma, middle ear surgery, inner ear
             barotrauma); age-related hearing loss; resolved otitis media; ototoxic drug exposure.

          -  Subject is willing to comply with the protocol and attend all study visits.

        Exclusion Criteria:

          -  Subject has pulsatile tinnitus, tinnitus resulting from traumatic head or neck injury,
             or tinnitus resulting from a tumor or stroke.

          -  Subject is pregnant or lactating.

          -  Subject has other clinically significant illness, medical condition or medical history
             at Screening or Baseline (Day 1) that, in the Investigator's opinion, would likely
             reduce the safety of study participation or compliance with study procedures.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient's own account: I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Clinical trial: The Effect of Financial Incentives on Utilization of Low-cost Providers

Eligibility criteria:
Inclusion Criteria:

        - Employee or dependent of an intervention or control employer

        Exclusion criteria:

        - Not continuously enrolled in health plan and therefore some claims may be missing
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Menstrual Cycle Hormones and Eating Behavior

Eligibility criteria:
Inclusion Criteria:

          -  Body Mass Index between 20-30 Kg/m2

          -  regular menstrual cycles

          -  sedentary lifestyle (physical activity not more than 30 minutes per day three times a
             week)

        Exclusion Criteria:

          -  Fasting blood sugar greater than 110 mg/dL

          -  Systolic Blood Pressure greater than 140 mmHg

          -  Diastolic Blood Pressure greater than 90 mmHg

          -  Fasting triglycerides greater than 120 mg/dL

          -  Documented or self-reported chronic disorders such as arthritis, or other inflammatory
             diseases

          -  Women who are Post-menopausal or Peri-menopausal

          -  Pre-menopausal women who are pregnant, uni/multiparous, taking oral contraceptives, or
             who have menstrual cycles lasting less than 20 days or greater than 45 days,
             polycystic ovary syndrome (PCOS), amenorrhea, eumenorrhoea, or polymenorrhoea.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 35 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: MRI Study of Stomach Volumes and Satiety

Eligibility criteria:
Inclusion criteria:

          -  Apparently healthy; no medical conditions that might affect the study measurements (as
             determined by the study physician)

          -  No use of medication that would interfere with the study measurements (as determined
             by the study physician)

          -  No use of antibiotics in the 3 months before the study or during the study

          -  No reported participation in another nutritional or biomedical trial 3 months before
             the study or during the study

          -  Being used to eating 3 meals daily

          -  BMI: 20 - 35 kg m-2

          -  No reported participation in night shift work 2 weeks prior to the study or during the
             study

          -  Not taking part in strenuous exercise ≤10 hours/week

          -  Not consuming more than 21 alcoholic test meals in a typical week

          -  Not presently a smoker

          -  No reported weight loss or gain of more than 10 % of bodyweight for 6 months before
             the study

          -  No eating disorder

          -  No MRI contraindications; i.e absence of metal implants, infusion pumps and
             pacemakers, as assessed by a MRI safety screening questionnaire

        Exclusion criteria:

          -  High or very high restrained eater

          -  Use of any medically- or self-prescribed diet for the duration of the study

          -  Allergies or food intolerances
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: MSCs For Treatment of Azoospermic Patients

Eligibility criteria:
Inclusion Criteria:

          -  All Non obstructive Azoospermic Patients.

          -  Azoospermic Patients due to Administration of Chemo/Radiotherapy.

        Exclusion Criteria:

          -  Patients with Testicular Cancer.

          -  Patients with Complete Deletion of Chromosome Y AZF (a,b,c) Regions.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction