Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient's own account: I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Clinical trial: Lipidome and Microbiome Profile of the Eye in Rosacea

Eligibility criteria:
Inclusion Criteria for subjects:

          -  Aged 18 and older

          -  Subjects that meet one of the following criteria:

               -  Healthy subjects without an inflammatory facial rash or an inflammatory eye
                  condition

               -  Subjects diagnosed with ocular rosacea or cutaneous rosacea (papulopustular or
                  erythematotelangiectatic) by either a board-certified dermatologist or
                  ophthalmologist

        Exclusion Criteria

          -  Those who are prisoners or cognitively impaired.

          -  Those who have had any change to their hormonal birth control regimen in the last 4
             weeks

          -  Systemic antibiotic use in the last four weeks

          -  Allergy or known intolerance to tetracyclines

          -  Those who wear contact lenses

          -  Autoimmune disease such as lupus, dermatomyositis that has cutaneous involvement

          -  Those who are pregnant or may become pregnant
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Precision Assessment of Platelet Rich Plasma for Joint Preservation

Eligibility criteria:
Inclusion Criteria:

          -  symptomatic early knee OA

          -  full weight-bearing status

          -  have elected to receive PRP treatment

          -  Male veterans

          -  Female veterans or non-veterans

        Exclusion Criteria:

          -  inflammatory arthritis, gout or recurrent pseudogout

          -  symptomatic OA of other lower extremity joints

          -  BMI >35 kg/m2

          -  use of walking, orthopedic, or prosthetic assistive device

          -  severe systemic disease defined as American Society of Anesthesiologists (ASA) 3 or
             above56

          -  inability to have MRI

          -  pregnant or intending to become pregnant during the study

          -  predominantly patellofemoral disease
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Treatment of Dysphagia by Using a Synchronized Electrical Stimulation Device

Eligibility criteria:
Inclusion Criteria:

          -  who have dysphagia symptoms and verified deglutition disorder by video fluoro
             swallowing study

        Exclusion Criteria:

          -  who reject the checkup their deglutition function by high resolution manometry

          -  who reject apply "Synchronized Electrical Stimulator"
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Woodsmoke Exposure and Cardiovascular Function

Eligibility criteria:
Inclusion Criteria:

          -  Healthy volunteers

        Exclusion Criteria:

          -  Use of regular medication except the oral contraceptive pill

          -  Current smokers

          -  Significant occupation exposure to air pollution

          -  Intercurrent illness
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: A Retrospective Validations Microsatellite Instability (MSI) Testing v Mismatch Repair (MMR) in Gastric Adenocarcinoma

Eligibility criteria:
Inclusion Criteria:

          -  Patient consent

          -  Adequate tissue including adequate tumour burden

          -  Diagnosis of adenocarcinoma in this biopsy

        Exclusion Criteria:

          -  No patient consent

          -  Inadequate tissue or block not present in archive

          -  No adenocarcinoma in biopsy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Strongest Predictors of a Positive Outcome After Physiotherapy for Knee Osteoarthritis

Eligibility criteria:
Inclusion Criteria:

          1. Clinical and radiological osteoarthritis of the knee and referred to physiotherapists.

          2. Symptomatic daily during the last month.

          3. Symptomatic for more than one year.

          4. Able to walk up and down a flight of 10 stairs with or without walking aids.

          5. Able to walk 3 stairs up and down without walking aids.

          6. Understand Norwegian orally and in writing.

          7. Body mass index below 35.

        Exclusion Criteria:

          1. Neurological, rheumatic, orthopedic, or respiratory diagnosis, other than
             osteoarthritis of the knee which can negatively affect the walking ability, balance or
             pain.

          2. Body mass index above or equal to 35.

          3. Fracture of the femur or shank, or arthroscopic surgery in the osteoarthritic knee.

          4. Chronic generalized pain (American College of Rheumatology Criteria, 2010).

          5. Inability to understand Norwegian language.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 45 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Suloexide in the Treatment of Early Stages of COVID-19

Eligibility criteria:
Inclusion Criteria:

          -  3 days or less with clinical COVID-19 symptoms (fever, cough, sour throat, headache,
             body ache, anosmia, diarrhoea, vomiting).

          -  sign inform consent.

          -  >50% risk developing a severe clinical presentation of COVID-19 according to risk
             calculator

        Exclusion Criteria:

          -  COVID-19 negative test

          -  known pregnancy

          -  chronic use of steroid medication

          -  deep vein thrombosis in the last 6 months

          -  extended anticoagulation in the last 3 months.

          -  known allergy to sulodexide.

          -  severe symptoms that warrant hospital care at initial screening
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient's own account: I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Clinical trial: Tranexamic Acid (TA) vs Combined Oral Contraceptive (COCP) Pilot Study

Eligibility criteria:
Inclusion Criteria:

          1. Menstruating females with menorrhagia or menometrorrhagia referred to hematology or
             gynecology clinics at Texas Childrens Hospital. Menorrhagia is defined as regular
             periods with heavy menstrual bleeding with a PBAC score greater than 100;
             menometrorrhagia is heavy vaginal bleeding occurring at irregular intervals.

          2. PBAC Score greater than 100 for 2 consecutive cycles

          3. Pelvic ultrasound that excludes pelvic pathology that can cause menorrhagia within 12
             months prior to study participation.

          4. Normal external genitalia examination within 6 months prior to study participation.

          5. Normal thyroid stimulating hormone (TSH) in the last 6 months prior to study
             participation.

          6. Negative urine or serum pregnancy test within 4 weeks prior to study participation.

        Exclusion Criteria:

          1. Presence of intra uterine device.

          2. Presence of a diagnosed bleeding disorder based on the standard work-up including
             complete blood count (CBC), prothrombin time, partial thromboplastin time, fibrinogen,
             von Willebrand panel and platelet function analysis (PFA-100) or platelet aggregation.

          3. Intake of medications with increased risk of bleeding

          4. Taking herbal products.

          5. Sexually active status.

          6. Body weight less than 40 kg.
Female
No healthy subjects accepted to join the trial.

Subject must be at most 21 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: Postural Analysis in Patients With Knee Osteoarthritis

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of Osteoarthritis Disease

        Exclusion Criteria:

          -  Others Disease orthopedics
Female
Accepts Healthy Volunteers
Subject must be at least 60 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient's own account: I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Clinical trial: Tanita BIA System Validation

Eligibility criteria:
Inclusion Criteria:

          -  Being either male or female

          -  Being from 5 to 80 years of age

          -  Being considered normal weight, overweight, or obese based on specified BMI ranges

          -  Having a bodyweight of less than 440 pounds

          -  Being willing to comply with the study procedures

        Exclusion Criteria:

          -  Having metal-containing objects in your body

          -  Being pregnant or attempting to become pregnant

          -  Being claustrophobic

          -  Having medical implants such as a pacemaker or metal joint replacements

          -  Being a professional athlete or someone with severe oedema or dehydration

          -  Having a body weight greater than 440 pounds
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 5 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Upper GI Handling of Branded vs. Generic Alendronate

Eligibility criteria:
Inclusion Criteria:

          -  Post-menopausal females aged greater 55 years

          -  Prescribed alendronate 70 mg tablets for a therapeutic indication throughout the
             previous 3 months and expected to continue on this treatment for the duration of the
             study

          -  Willing to abstain from alcohol for 24 hours before each dose and until the end of
             each study day

          -  Willing to abstain from smoking for 24 hours before each dose and until the end of
             each study day

        Exclusion Criteria:

          -  History of drug hypersensitivity

          -  Suffers from dysphagia, achalasia, or other conditions or medications affecting upper
             gastrointestinal motility
Female
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction