Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: SpO2 System Accuracy Testing With Different Sensors

Eligibility criteria:
Inclusion Criteria:

          -  Ability to provide written informed consent or have a legally authorized
             representative provide written informed consent

          -  Subjects who are 18-55 years of age

          -  Subjects must be willing and able to comply with study procedures

          -  HbCO<3% (for smokers only)

        Exclusion Criteria:

          -  Subject or a legally authorized representative is unable to provide written inform
             consent.

          -  Subjects that are considered morbidly obese (defined as BMI > 39.5),

          -  Subjects with injuries, deformities or abnormalities that may prevent proper
             application of the device under test,

          -  Smokers with COHb levels >3% or subjects who have smoked within two (2) days. Subjects
             will be screened for COHb levels of >3% with a Masimo Radical 7 (Rainbow).

          -  Subjects with known respiratory conditions (uncontrolled asthma, head cold, flu,
             pneumonia / bronchitis, respiratory distress / respiratory or lung surgery, emphysema,
             COPD, lung disease),

          -  Subjects with known heart or cardiovascular conditions,

          -  Female subjects that are actively trying to get pregnant or are pregnant,

          -  Subjects taking blood thinners or medications with aspirin or other antiplatelet
             medication in them (applies only to arterial draw study),

          -  Subjects with Systolic blood pressure >140mmHg,

          -  Subjects with Diastolic blood pressure >100mmHg,

          -  Subjects with heart rhythms other than a normal sinus rhythm or with respiratory sinus
             arrhythmia
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Secretory Azoospermia and FDG (Fluoro Deoxyglucose) PET-CT

Eligibility criteria:
Inclusion Criteria:

        absence of sperm cells on 2 spermograms in 3 months interval testicular size has to be
        determined in order to categorized in a group to accept surgery-

        Exclusion Criteria:

        allergy to fluoro deoxyglucose clinical varicocele
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient's own account: I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Clinical trial: Topical Agent for Treatment of Red Skin

Eligibility criteria:
Bilaterally symmetric red skin on cheeks Caucasian Age 18-60 years
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 19-year-old male came to clinic with some sexual concern.  He recently engaged in a relationship and is worried about the satisfaction of his girlfriend. He has a "baby face" according to his girlfriend's statement and he is not as muscular as his classmates.  On physical examination, there is some pubic hair and poorly developed secondary sexual characteristics. He is unable to detect coffee smell during the examination, but the visual acuity is normal. Ultrasound reveals the testes volume of 1-2 ml. The hormonal evaluation showed serum testosterone level of 65 ng/dL with low levels of GnRH.

Patient's own account: I'm 19 years old guy and I just went to see a doctor at the clinic after I just got with my girlfriend. I'm kinda worried because she thinks that I have a baby face and to be honest, I'm way less muscular than my classmates. I don't have much hair down there, and yes, I don't have that macho look. The doctor made me smell some coffee and I couldn't smell anything special. I also had some eyesight checkups and the doctor told me everything was normal. I got my test results back and it says: testes volume is 1-2 ml and serum testosterone level of 65 ng/dL with low GnRH levels.

Clinical trial: Study of Comprehensive Diagnosis and Treatment for Children Precocious Puberty

Eligibility criteria:
Inclusion Criteria:

          1. Premature appearance of secondary sexual characteristics: girls present with
             development of secondary sexual characteristics before 8, with breast induration as
             the earliest manifestation.

          2. Accelerated linear growth: the annual growth rate is higher than normal.

          3. Advanced bone age: the bone age is 1 or years more than the actual age

          4. Enlargement of sexual glands: B-mode ultrasonography of pelvic cavity indicates the
             volumes of the uterus and ovaries have increased, and multiple ovarian follicles with
             a diameter>4mm can be found in ovaries;

          5. HPGA functions have been primed; serum gonadotropin and sexual hormone levels reach
             pubertal values.

          6. Subjects should be willing and able to follow the study protocol during the study
             period.

          7. Subjects should submit their parents' or guardians' written informed consent before
             initiation of the study procedure with non-normal medical care. They should understand
             that subjects or their parents/guardians may withdraw the consent at any time without
             impairing future medical care. If the child is old enough to read and write, she
             should submit a separate consent form.

        Exclusion Criteria:

          1. Patients with central nervous system diseases and thyroid diseases;

          2. Patients with CHA-induced precocious puberty;

          3. Patients with poor compliance.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.
Subject must be at most 14 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Calibration and Validation of High Quality Low-Cost 3D Printed Pulse Oximeter

Eligibility criteria:
Inclusion Criteria:

        - This study has 2 Phases. In Phase 1, healthy, non-smoking adult volunteers greater than
        18 years of age are invited to participate. In Phase 2, all adult (>18) non-critical
        patients and healthy community volunteers visiting the ED at VH and UH are eligible to
        participate.

        Exclusion Criteria:

        Potential participants will be excluded based on the following criteria:

        Phase 1:

          -  greater than 70 years of age,

          -  current smokers,

          -  previous history of cardiac disease (e.g., atrial fibrillation, myocardial infarction,
             congestive heart failure),

          -  history of moderate or severe asthma,

          -  history of seizures,

          -  history of stroke or transient ischemic attack

          -  pregnant women

          -  Patients with any active pulmonary disease such as pneumonia

          -  Individuals who are unwilling to participate or are less than 18 years old

          -  Those who are unable to consent

        Phase 2

          -  Critical patients will be excluded from participating

          -  Individuals who are unwilling to participate or are less than 18 years old will be
             excluded

          -  Those who are unable to consent.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Growth Hormone Secretion Following the Anaerobic Exercise

Eligibility criteria:
Inclusion Criteria:

          -  Children evaluated for short stature

          -  Normal weight \ overweight \ obesity

        Exclusion Criteria:

          -  Known GH deficiency
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 6 Years old.
Subject must be at most 16 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient's own account: I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Clinical trial: Vision Response to Dopamine Replacement

Eligibility criteria:
Inclusion Criteria:

          -  clinical diagnosis of oculocutaneous albinism

          -  age over 3 and weight over 25 lbs.

        Exclusion Criteria:

          -  ocular only albinism

          -  ocular pathology other than albinism

          -  neurologic disease, history of myocardial infarction, history of clinical depression,
             pregnancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: To Access the Egyptian COVID-19 Whole Genome by NGS and Compare to the International Worldwide Database

Eligibility criteria:
Inclusion Criteria:

        Patients With confirmed COVID-19

        Exclusion Criteria:

        inadequate sample of the patients
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 51-year-old man comes to the office complaining of fatigue and some sexual problems including lack of libido. The patient doesn't smoke or use any illicit drug.  Blood pressure is 120/80 mm Hg and pulse is 70/min.  Oxygen saturation is 99% on room air.  BMI is 24 kg/m2.  Skin examination shows increased pigmentation. Genotype testing is consistent with homozygosity for the C282Y mutation. Laboratory study shows transferrin saturation of 55% and serum ferritin of 550 μg/L. He is diagnosed as a case of hemochromatosis.

Patient's own account: I am 51 years old and I just came back from the doctor's office. I'm sick and tired of being that exhausted, reaching the point where me and my lovely wife are not touching each other anymore! I'm not smoking or doing drugs! My blood pressure was 120/80 mm Hg, and pulse was 70/min and my oxygen saturation 99%. My BMI is 24. My skin also turned a bit darker lately. He tested my genes and told me that I have a mutation of the C282Y gene. I also did lab tests where my transferrin saturation was 55% and serum ferritin was 550  μg/L. The doctor diagnosed me with iron overload.

Clinical trial: Hemochromatosis and Iron Overload Screening Study (HEIRS)

Eligibility criteria:
No eligibility criteria
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short Stature

Eligibility criteria:
Inclusion Criteria:

          -  Children with short stature by growth hormone deficiency(GHD) or idiopathic short
             stature (ISS) or turner's syndrome(TS) or small for gestational age(SGA)

          -  Children who has official height record at least 6 months prior

        Exclusion Criteria:

          -  Children with Epiphyseal closure
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 2 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Osteoporosis School

Eligibility criteria:
Inclusion criteria:

          -  fracture caused by osteoporosis

          -  fifty years or more of age

          -  informed consent

        Exclusion criteria:

        - Physically or mental state that does not participation
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Russian Kogenate Pediatric Study

Eligibility criteria:
Inclusion Criteria:

          -  Male

          -  Severe hemophilia A or moderate hemophilia A

          -  1-12 years of age

          -  Requiring treatment with FVIII

        Exclusion Criteria:

          -  Current or prior inhibitor or familial antecedents of inhibitor

          -  Surgery required during the study (9 months)

          -  Positive for HIV
Male
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 12 Years

Eligibility (NLI label): Contradiction