Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Use of Parietex Plug and Patch Hernia System in Open Inguinal Hernia Repair

Eligibility criteria:
Inclusion Criteria:

          -  All patients regardless of gender > 18 years of age presenting with inguinal hernias.

          -  Subjects will be informed of the nature of the study, and have provided signed written
             consent.

        Exclusion Criteria:

          -  children under the age of 18

          -  subjects that meet criteria for biologic mesh placement

          -  emergency procedure

          -  recurrent hernias.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 70-year-old man comes to the office accompanied by his wife.  The patient has experienced progressive memory loss over the last years.  He needs help with some of his routine activities, such as paying bills.  The patient's wife says, "He used to be such an independent person, but now he needs help with many things, even finding direction to home!"  Medical history includes hypertension, hyperlipidemia, and type 2 diabetes mellitus.  Family history includes Alzheimer disease in his father.  MRI reveals diffuse cortical and hippocampal atrophy. The diagnosis of AD is made using the National Institute on Aging and the Alzheimer's Association (NIA-AA) criteria.

Patient's own account: I am a 70-year-old man, and I paid a visit to the doctor with my wife the other day. I noticed that I tend to forget small things and that my memory has decreased over the past few years. I even ask my wife to help me out with my daily routine. I used to be the one paying the bills, but now she has to give me a hand. My wife mentioned to the doctor that I used to be independent and that I tend to forget where we live. I suffer from hypertension, high cholesterol, and type 2 diabetes. My poor dad was suffering from Alzheimer disease, so I hope I'm not going to end the same way! I did an MRI and they found out that some part of my brain was decreasing. I also did an Alzheimer test.

Clinical trial: LifeZig Personalized Reminiscence Video With Slideshows and Music for Individuals With Alzheimer's and Dementia

Eligibility criteria:
Inclusion Criteria:

          -  Inclusion criteria for dementia patients:

               -  documented diagnosis of probable Alzheimer's or other type of dementia, medically
                  stable, and visual/hearing capabilities to watch television.

          -  Inclusion criteria for family members/caregivers:

               -  provide care or be a family member of dementia patient, have knowledge of the
                  person, and be able to provide old photographs of dementia patient.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: Nutrition Education Module for Preschooler Children

Eligibility criteria:
Inclusion Criteria:

          -  children registered in selected public kindergarten

          -  grade/class B kindergarten

          -  willing to follow the study

        Exclusion Criteria:

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.
Subject must be at most 7 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 15-week-old infant brought to the clinic for the follow up. The infant has flat facies, small ears, a single palmar crease, and upward slanting eyes. He was born on 39th week to a 39-year-old woman who didn't have prenatal care. The medical record confirms the trisomy of chromosome 21 (Down syndrome). The infant is otherwise healthy.

Patient's own account: My newborn, who is only 15 weeks old, had one of his follow-up appointments. The doctor pointed out that my baby had a flat face, small ears, only one palm line, and small eyes. He was born on his 39th week, while I was 39. What a coincidence! To be honest, I did not go to the doctor during my pregnancy. The doctor diagnosed my baby with Down syndrome. Apart from that he's healthy.

Clinical trial: Face Anthropometric Pattern Recognition Technology for Computer Aided Diagnosis of Human Genetic Disorders.

Eligibility criteria:
Inclusion Criteria:

          -  all newborn infants born at the Carmel Medical Center following parental consent, and
             at Soroka Medical Center.

        Exclusion Criteria:

          -  No parental consent; Facial deformation not related to chromosomal or genetic
             anomalies; babies transferred to the neonatal intensive care unit that need
             ventilatory support.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers

Subject must be at most 2 Weeks

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: Multicentre Study Comparing Indwelling Pleural Catheter With Talc Pleurodesis for Malignant Pleural Effusion Management

Eligibility criteria:
Inclusion Criteria:

          -  Symptomatic malignant pleural effusion requiring intervention

        Exclusion Criteria:

          -  <18 years of age

          -  pregnant or lactating patients

          -  expected survival <3 months

          -  chylothorax

          -  previous attempted pleurodesis

          -  pleural infection

          -  leukocytopaenia (<1.0 x 10^9/L)

          -  uncorrectable bleeding diathesis

          -  inability to give informed consent or comply with the protocol
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain

Eligibility criteria:
Inclusion Criteria:

          -  Is a healthy adult 18 to 75 years of age, inclusive, in general good health and with
             diagnosis of knee OA, as determined by the American College of Rheumatology (ACR)
             clinical/radiographic classification criteria for OA of the knee.

          -  Women must be of non childbearing potential (amenorrhea for at least 1 year PLUS have
             a serum follicle stimulating hormone (FSH) level >30 IU/L, bilateral oophorectomy or
             hysterectomy), and have a confirmed negative serum pregnancy test at the screening
             visit prior to randomization.

        Exclusion Criteria:

          -  History of other diseases that may involve the study joint, including inflammatory
             joint diseases, crystalline disease, endocrinopathies, metabolic diseases, infections,
             neuropathic disorders, avascular necrosis, Paget's disease, or tumors.

          -  Women of childbearing potential, or who are pregnant or lactating.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: Effect of Muscle Strength on Hamstring Flexibility in Children With Duchenne Muscular Dystrophy

Eligibility criteria:
Inclusion Criteria:

          -  Getting a Duchenne Muscular Dystrophy diagnosis,

          -  Being in ambulatuar phases and independently climbing four stairs

          -  To be cooperate to physioterapist's directions

        Exclusion Criteria:

          -  Having severe contracture in the lower extremity

          -  Having undergone surgery in the past 6 months
Male
No healthy subjects accepted to join the trial.
Subject must be at least 5 Years old.
Subject must be at most 18 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: The Effect of Telerehabilitation of Patients With Duchenne Muscular Dystrophy

Eligibility criteria:
Inclusion Criteria:

          -  Patients with Duchenne muscular dystrophy

        Exclusion Criteria:

          -  Patients without the ability of independent ambulation
Male
No healthy subjects accepted to join the trial.
Subject must be at least 6 Years old.
Subject must be at most 18 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Can Ibuprofen Delay Ovulation in Natural Cycle-IVF?

Eligibility criteria:
Inclusion Criteria:

          -  Indication for NC-IVF

          -  Wish for NC-IVF

          -  Menstruation every 26-32 days

          -  Accessibility of both ovaries for a follicle aspiration

          -  18-42 years of age

          -  Written informed consent

          -  Indication for IUI or TSI

          -  Wish for IUI or TSI

        Exclusion Criteria

          -  <18 and >42 years of age

          -  Gastro-intestinal diseases

          -  Known Ibuprofen Intolerance
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 42 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Evaluation of People With Gastrointestinal Disease

Eligibility criteria:
-  INCLUSION CRITERIA:

          -  Known or suspected gastrointestinal disorders.

          -  Patients greater than or equal to 18 years of age capable of providing informed
             consent.

          -  Existence of a referring community physician who would be able to manage care outside
             of the NIH.

        EXCLUSION CRITERIA:

          -  Significant medical illnesses that the investigators feel may interfere with potential
             evaluations.

          -  Any medical, psychiatric, or social conditions which, in the opinion of the
             investigators, would make participation in this protocol not in the best interest of
             the patient.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Wearable Pulsed Electromagnetic Fields Device in Knee Osteoarthritis: Double Blinded, Randomized Clinical Trial

Eligibility criteria:
Inclusion Criteria:

          -  a diagnosis of primary OA of the knee according to the ACR criteria, including
             radiologic evidence of OA

          -  age >40 years

          -  symptomatic disease for at least 6 months prior to enrollment

          -  persistent pain despite receiving the maximum tolerated doses of conventional medical
             therapy, including acetaminophen (4 gm/day) and/or a nonsteroidal antiinflammatory
             drug (NSAID), with persistent pain defined as a minimum mean score of 25 mm on the
             visual analog scales (VAS) for global pain (0-100-mm range for each) daily pain during
             the month prior to study enrollment

          -  ability to attend followup appointments

        Exclusion Criteria:

          -  secondary causes of OA

          -  local or systemic infection

          -  diabetes mellitus

          -  systemic arthritis

          -  allergy to anesthetic agent or contrast material

          -  coagulopathy

          -  anticoagulant therapy

          -  had previous IA steroid injection

          -  avascular necrosis of bone

          -  patients who are on specific OA pharmacological therapy (NSAIDS, opioids) for more
             than 2 weeks prior enrollment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 40 Years old.


Eligibility (NLI label): Entailment