Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Contribution of the Somatosensory System to Speech Perceptual Processing

Eligibility criteria:
Inclusion Criteria:

          -  right handed adults

          -  no known physical or neurological abnormalities

        Exclusion Criteria:

          -  patients with:

          -  cardiac pacemaker

          -  surgical clips or values on the heart

          -  implants

          -  metal or metallic fragments in any part of the body

          -  pregnancy

          -  claustrophobia

          -  a personal or family history of epilepsy

          -  currently taking antipsychotic drugs

          -  currently taking antidepressant drugs

          -  currently taking antianxiety drugs.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 21 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Feel Breathe, Restriction Device Ventilatory Nasal

Eligibility criteria:
Inclusion Criteria:

          -  Age: 25-35 years.

          -  trained male caucasian cyclists

          -  Non-smokers

          -  Each subject completed an approved informed consent form and detailed health
             questionnaire before testing.

        Exclusion Criteria:

          -  Smokers.

          -  Presence of diseases during the test period. In particular, they had no current
             symptoms of nasal disease, snoring, asthma or allergic rhinitis.

          -  Unwillingness to complete the study requirements.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 35 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient's own account: I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Clinical trial: Study of the Correlation Between UltraSonography and Dual-Energy Computed Tomography Assessment of Urate Deposit

Eligibility criteria:
Inclusion Criteria:

          -  diagnosis of gout based on the ACR/EULAR 2015 criteria

          -  uricemia ≥6 mg/dL

          -  warranted introduction of urate-lowering therapy according to the ACR 2012 or EULAR
             2016 criteria

          -  signature of the informed consent

          -  social insurance affiliation

        Exclusion Criteria:

          -  pregnancy or breastfeeding

          -  patient under legal guardianship
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 (FALCON-C19)

Eligibility criteria:
Work Stream A (in-hospital; Group 1 and Group 2):

        Group 1 Inclusion Criteria:

        We will include participants (patients or staff):

          1. That are 18 years or older

          2. That will require testing for COVID-19 in the opinion of the treating clinician

          3. That may have presented with acute symptoms of COVID-19 (e.g. fever, cough, dyspnoea,
             anosmia) or chest x-ray changes or they may be asymptomatic but require testing for
             other reasons

        Group 2 Inclusion Criteria:

        We will include participants:

          1. That are 18 years or older

          2. That have been admitted for another reason other than suspected SARS-CoV-2 infection,
             but when routinely swabbed they have been identified as positive for SARS-CoV-2 PCR

        Work Stream B (Group 3):

        We will include participants:

          1. That are 18 years or older

             EITHER:

          2. They have been identified as positive for SARS-CoV-2 PCR through testing at national
             laboratory infrastructure OR

          3. They have been identified as negative for SARS-CoV-2 PCR through testing at national
             laboratory infrastructure

        Work Stream C (Group 4):

        We will include participants:

          1. That are 18 years or older

          2. Who are undergoing testing for COVID-19, whether they are symptomatic or symptomatic
             for COVID-19

        Exclusion Criteria for all Work Streams:

          1. Patients where it is impossible/unsafe to obtain the required research samples

          2. Prisoners

          3. Patients where sampling is not feasible
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Evaluation of the Reliability of the Determination of MisMatch Repair Deficiency Status by Endoscopic Biopsies in Oesophagus and Gastric Adenocarcinoma.

Eligibility criteria:
Eligible criteria :

          -  Patient having endoscopic oesogastroduodenal endoscopy for suspicion of
             oesogastro-duodenal adenocarcinoma.

          -  Benefiting from the social security system

        Inclusion Criteria:

          -  Patient having endoscopy biopsies in front of a suspicious lesion suggestive of
             gastroesophageal adenocarcinoma

        Exclusion Criteria:

          -  Minor patient (<18 years old)

          -  known pregnancy

          -  Major patient under tutorship or curatorship

          -  Contraindication to gastric biopsies
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient's own account: The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Clinical trial: Musculoskeletal Pain in Long-term Dizziness

Eligibility criteria:
Inclusion Criteria:

          -  Patients referred to an otorhinolaryngological university clinic due to suspected
             vestibular disorders (dizziness)

          -  Patients must be bothered with dizziness at the time of consultation

        Exclusion Criteria:

          -  Patients uable to fill in questionnaires due language barriers

          -  Patients not able to undergo diagnostic and testing procedures

          -  Patients with vestibular Schwannoma

          -  Patients with diving-related inner ear injuries
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 67 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient's own account: I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Clinical trial: Extension Study of Biostate in Subjects With Von Willebrand Disease

Eligibility criteria:
Inclusion Criteria:

          -  Have completed Study CSLCT-BIO-08-52 (Assessment of Efficacy and Safety of Biostate in
             Paediatric Subjects with Von Willebrand Disease) or Study CSLCT-BIO-08-54 (Assessment
             of Efficacy and Safety of Biostate in Adolescent or Adult Subjects with Von Willebrand
             Disease).

          -  The subject and/or his/her legal guardian understand(s) the nature of the study and
             has/have given written informed consent to participate in the study and is/are willing
             to comply with the protocol.

        Exclusion Criteria:

          -  Early discontinuation of a subject from the main studies CSLCT-BIO-08-52 or
             CSLCT-BIO-08-54.

          -  Mental condition rendering the subject (or the subject's legal guardian) unable to
             understand the nature, scope and possible consequences of the study.

          -  Any condition that is likely to interfere with evaluation of the IMP or satisfactory
             conduct of the study.

          -  Are not willing and/or not able to comply with the study requirements.

          -  Employee at the study site, or spouse/partner or relative of the Investigator or
             Subinvestigators.

          -  Female subjects of childbearing potential either not using, or not willing to use, a
             medically reliable method of contraception for the entire duration of the study, or
             not sexually abstinent for the entire duration of the study, or not surgically
             sterile.

          -  Intention to become pregnant during the course of the study.

          -  Pregnancy, or nursing mother.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Study Of The Metabolic Parameters Of Uterine Muscle Cells

Eligibility criteria:
Inclusion criteria:

          -  - Adult patient

          -  Patient benefiting from the routine management of a programmed hysterectomy by
             vaginal, laparoscopic or laparotomy for benign pathologies (fibroma, adenomyosis,
             genital prolapse,...) within the CMCO

          -  Patient consenting to the use of cells from her uterus for incineration for research
             purposes

          -  Patient giving her consent for the use of her medical data for the purposes of this
             research.

          -  Patient agreeing to participate in the study

        Exclusion criteria:

          -  - Patient refusing to participate in the study

          -  Patient under the protection of justice

          -  Patient under guardianship or curatorship

          -  Suspicion of gynaecological malignant pathology

          -  Pregnant or breastfeeding woman

          -  Impossibility to give the subject informed information (difficulties in understanding
             the subject...)
Female

Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH

Eligibility criteria:
Inclusion Criteria:

          -  Had a hiatal hernia repair with MIROMESH greater than 6 months prior to study

        Exclusion Criteria:

          -  N/A
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Effects of Whole Body Vibration on Postmenopausal Risk-factors in Elderly Women

Eligibility criteria:
Inclusion Criteria:

          -  females 60 - 75 years old

          -  caucasian race

        Exclusion Criteria:

          -  CHD-diseases

          -  thrombosis, embolism

          -  fractures at lumbar spine or hip

          -  secondary osteoporosis

          -  hyperparathyroidism

          -  medication, diseases with impact on muscle or bone

          -  hip or knee implant
Female
Accepts Healthy Volunteers
Subject must be at least 60 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction