Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Study of Compensatory Motion While Using an Upper Limb Prosthesis

Eligibility criteria:
Inclusion Criteria:

          -  ages 18-60 years old

          -  Control group: normal, healthy volunteers

          -  Amputee group: unilateral, transradial myoelectric prosthesis users

        Exclusion Criteria:

          -  elderly > 60

          -  children < 18

          -  pregnant women

          -  persons with shoulder impairments, injuries, or problems

          -  bilateral upper limb amputees
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 7-year-old girl is brought to the emergency department by her parents for generalized rash.  The mother reports that she was playing outside wearing a skirt and felt a sharp pain in her arm while seating on a mat, plying with her doll.  Her mother suspects that something had stung her.   The patient's blood pressure is 75/55 mm Hg and her heart rate is 122/min.  Physical examination shows erythematous, raised plaques over the trunk, extremities, and face.  Lung auscultation reveals bilateral expiratory wheezes.

Patient's own account: I just brought my seven-year-old girl to the ER because she just developed a terrible rash. My little girl was playing outside and she was wearing a lovely little skirt and all of a sudden. She felt like a really sharp pain in her arm. She was sitting on a mat playing with her doll. I think that something stung her. They took her blood pressure, and it turned out to be 75 out of 55. Her heart rate was 122. Then they did a physical examination, and it showed rashes all around her trunk, extremities, and face. Her breath test revealed some high-pitched breathing.

Clinical trial: The Effect of Medical Clowns on Blood Pressure Measurement in Children Presenting to the Emergency Department

Eligibility criteria:
Inclusion Criteria:

          -  Children aged 1 day to 18 years presenting to the ED.

        Exclusion Criteria:

          1. Serious medical condition requiring emergent medical care or resuscitation

          2. Parental refusal to participate in the study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers

Subject must be at most 18 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient's own account: I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Clinical trial: Prevalence of Female Circumcision Among Young Women in Beni-Suef, Egypt

Eligibility criteria:
Inclusion Criteria:

          -  Young women aged 12 to 25 years living in Beni-Suef city of Egypt. the urban
             Metropolitan of Beni-Suef City was classified according to the socioeconomic level of
             its quarters to low, middle, and high levels. Out of each level, one quarter was
             selected randomly, by a card withdrawal, where households residing these quarters were
             chosen using a random start. For the rural villages surrounding the urban
             Metropolitan, three villages were selected randomly; one on the road to the North, one
             on the road to the West, and the last one on the road tothe South. Each village was
             clustered roughly into two sites; one to the East of the water channel and one to the
             West of the same water channel

        Exclusion Criteria:

          -  Women from other places in Egypt.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 25 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient's own account: I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Clinical trial: Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients

Eligibility criteria:
Inclusion Criteria:

          -  Have persistent facial erythema on the cheeks of at least moderate severity.

          -  Women must not be able to bear children

        Exclusion Criteria:

          -  Have more than 12 inflammatory lesions on the face

          -  Previous treatment of facial skin with lasers or electrocauterisation within 2 months
             prior to entering the study

          -  Have facial hair that makes it difficult to evaluate rosacea on the face Other
             protocol-defined inclusion/exclusion criteria may apply
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Cannabis and Parkinson's Disease Tremor: A Natural History Study

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of Parkinson's Disease

          -  Presence of PD-related tremor

          -  Currently using Cannabis for management of tremor

          -  Obtaining Cannabis in accordance with Washington State law

          -  Willing to log activities and experiences

          -  Willing to wear a motion sensor

          -  Able to attend 2 on-site visits

        Exclusion Criteria:

          -  Presence of active infection within 5 days prior to enrollment

          -  Presence of unusual stressor within 5 days prior to enrollment

          -  Pregnancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 39-year-old man comes to the emergency department with an acute onset of severe left toe pain.  The toe is red and exhibits swelling. The patient is not febrile, and does not remember any recent trauma. Medical history is not significant except for the similar attacks and the diagnosis of gouty arthritis. His medication history includes Allopurinol to prevent gouty attacks. His father has the same medical condition. However, his older brother who is 41 years old is healthy with no history of gouty arthritis. Physical examination shows a swollen, tender first metatarsophalangeal joint.  Aspiration of the joint showed high leukocyte count, negative Gram stain, and numerous needle-shaped crystals, which is compatible with gouty arthritis.

Patient's own account: I'm a 39-year-old man and got admitted to the ER after an unbearable pain in my left toe. My toe was red and terribly swollen. I was still standing on my feet, not febrile and I don't remember hitting my head or anything. I don't have any special medical history, but I had been diagnosed with gout before. I take Lopurin to prevent my gouty attacks. My dad had the same problem, but my 41-year-old brother is healthy and does not have gouty attacks. The doctor did a physical exam and found that the joints between my toes and the rest of my foot were swollen and tender. The doctor renewed his diagnosis of gouty arthritis.

Clinical trial: Treatment of Refractory Gout With ACTH or Methylprednisolone

Eligibility criteria:
Inclusion Criteria:

          -  (123 items and 1 item from 4-7 are met simultaneously) :

               1. Meet the 2015 ACR/EULAR classification diagnostic criteria for gout

               2. Acute gouty arthritis

               3. Age ≥18

               4. Repeated attacks and prolonged pain (more than 1 month);

               5. poor response or intolerance to colchicine or NSAIDs;

               6. Liver and kidney dysfunction;

               7. Old age;

        Exclusion Criteria:

          -  1) History of gastrointestinal bleeding and active ulcer 2) The application history of
             glucocorticoids and ACTH in 1 month before screening 3) Pregnancy and lactation 4)
             Drug and alcohol abuse 5) Malignant tumor (treated or untreated within 5 years) 6)
             Mental illness inability to communicate or have language barriers and inability to
             fully understand and cooperate 7) negligent compensatory heart failure, unstable
             angina pectoris, stroke, transient ischemic attack, myocardial infarction, and severe
             arrhythmia occurred within 6 months 8) The investigator did not consider it
             appropriate to participate in the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability

Eligibility criteria:
Inclusion Criteria:

          -  Radiographic evidence of knee OA on a standing AP X-ray

          -  Bilateral knee pain for at least 3 months with pain of at least moderate intensity
             every day or almost every day

        Exclusion Criteria:

          -  Non-ambulatory, or severely impaired mobility (i.e., require the use of a walker)

          -  Folstein Mini-Mental State Examination score of less than 24

          -  Severe visual or hearing impairment

          -  Knee pain due to factors other than OA, e.g. rheumatoid or psoriatic arthritis, gout,
             pseudogout, metastatic cancer

          -  Significant pain in parts of the body other than the knee or acute knee pain

          -  A large knee effusion or severe mechanical instability of the knee

          -  History of corticosteroid injection in the affected knee(s) during the preceding 3
             months

          -  History of hyaluronic acid injection in the affected knee(s) during the preceding 3
             months

          -  Acute or terminal illness

          -  Immune suppression

          -  Anticoagulation therapy

          -  Presence of a pacemaker

          -  Prior acupuncture treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Relationships Among Body Mass Index, Body Balance and Bone Mineral Density in Postmenopausal Women

Eligibility criteria:
Inclusion Criteria:

          -  postmenopausal women with ages range from 50 to 60 years

        Exclusion Criteria:

          -  participation in sports

          -  vertebrobasillar insufficiency

          -  poor diet
Female

Subject must be at least 50 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Soft and Hard Tissue Changes After Immediate Single-tooth Replacement

Eligibility criteria:
Inclusion Criteria:

          -  a single tooth to be extracted for endodontic failure, fractures, root caries or
             resorption in the maxillary and mandibular area from second premolar to second
             premolar

          -  patient in good systemic health, with no contraindication for oral surgical
             interventions

        Exclusion Criteria:

          -  patients with impaired systemic diseases that will interfere with surgical
             interventions (autoimmune diseases, uncontrolled diabetes)

          -  assumption of bisphosphonate

          -  smoking more than 10 cigarettes a day
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 39-year-old woman comes to the clinic complaining of arthralgias and nodules on her legs.  She has no fever or other skin rashes. The prior medical condition is unremarkable, and she takes no medications.  On physical examination, there is moderate hepatomegaly. The lesions on her legs are tender and present predominantly on the anterior surface of the lower extremities. She doesn't smoke and drinks alcohol occasionally. The patient has 2 male sexual partners. Vital signs are normal. Chest x-ray demonstrates enlarged hilar lymph nodes, and laboratory testing reveals an elevated ACE level. Biopsy of the skin lesion shows noncaseating granulomas that stain negative for fungi & acid-fast bacilli.

Patient's own account: I'm just a 39-year-old young woman but lately I have noticed some underlying cysts on my legs and my joints were hurting so much. I don't have a fever. I don't have rashes. My medical history is totally clean and I don't take any medication. When I went to the clinic they did a physical examination where they found that my liver is enlarged. They also found that the lesions on my legs are kind of tender and they are located on the front side of my legs. I do not smoke and I drink alcohol occasionally. I have to male sexual partners. On the day of my visit my vitals were fine. I did an X-ray of my chest and I had swollen lymph nodes. I also has a blood test and it came back with a high ACE level. I also had a biopsy of my skin lesions that came back negative for fungi and AFB.

Clinical trial: Muscle Strength and Exercise Capacity in Sarcoidosis Patients

Eligibility criteria:
Inclusion Criteria:

          -  diagnosed sarcoidosis according to WASOG/ATS/ERS guidelines

        Exclusion Criteria:

          -  not being able to walk
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers



Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Web-based Adherence Information Integrated Nurse-led Monitoring Clinic

Eligibility criteria:
Inclusion Criteria:

          -  All patients who receive easypod GH of age 1-14 years will be approached for consent
             to participate in the study. Patients may have any valid cause for short stature.
             These may include children with

          -  isolated growth hormone deficiency

          -  multiple pituitary hormone deficiencies

          -  non-growth hormone deficient conditions such as

          -  Small for gestational age with postnatal failure of height gain

          -  chronic renal failure and

          -  Turner syndrome. Patients will be recruited to the study irrespective of diagnosis and
             will not be stratified by diagnosis at entry to the study. However, in analysis of
             data, subgroup analysis may be performed on groups such as those with isolated growth
             hormone deficiency, dependent on the frequency of recruitment.

        All patients will be identified at the start of the study. A one month period will be
        considered before the study commences to contact families for potential recruitment. Each
        patient will remain in the study for 12 months. The active study duration will be 18 months
        whereby all eligible patients will be recruited and followed up for a 12 month period. This
        period will be followed by a buffer period to gather necessary data for analysis.

        Exclusion Criteria:

          -  Patients on growth hormone treatment but using other growth hormone devices Patients
             who are younger or older than the age limits.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 14 Years

Eligibility (NLI label): Entailment