Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

Eligibility criteria:
Inclusion Criteria:

          -  Age ≥50 years old OR primary healthcare professional (defined as having a job that has
             had direct patient contact during the COVID-19 pandemic) and ≥18 years old

          -  No symptoms of COVID-19 (a fever of 100.0o F or greater, OR a new cough, OR new
             shortness of breath, OR new sore throat, OR new diarrhea, OR new fast breathing
             (respiratory distress), OR new chills, OR new muscle aches (myalgias), OR new loss of
             smell, OR new change or loss of taste sensation) in the past 7 days

          -  Have a negative Elecsys Anti-SARS-CoV-2 immunoassay antibody test at screening

          -  Have not had close contact with a person with a LABORATORY CONFIRMED case of COVID-19
             without full PPE (Close contact is defined by CDC as: Being within approximately 6
             feet of a COVID-19 patient for a total of 15 minutes or more over a 24 hour period) or
             having direct contact with infectious secretions of a COVID-19 patient (e.g. being
             coughed on)) in the last 14 days

          -  Mayo Clinic patient who has a patient online account set up or is willing to set up an
             online account

          -  Must have a valid email address and internet service

        Exclusion Criteria:

          -  History of positive or indeterminate COVID PCR test prior to screening or Elecsys
             Anti-SARS-CoV-2 immunoassay antibody test positive or indeterminate at screening

          -  Active symptoms of COVID ((a fever of 100.0o F or greater, OR a new cough, OR new
             shortness of breath, OR new sore throat, OR new diarrhea, OR new fast breathing
             (respiratory distress), OR new chills, OR new muscle aches (myalgias), OR new loss of
             smell, OR new change or loss of taste sensation)) in past 7 days

          -  Known intolerance to multivitamins or zinc supplements from prior exposure

          -  Inability to complete follow-up questions or grant access to electronic health record
             for surveillance

          -  Have had close contact with a person with a LABORATORY CONFIRMED case of COVID-19 in
             past 14 days

          -  Current or former smoker less than 5 years ago

          -  Pregnant or breastfeeding

          -  Prisoner

          -  Any subject with known immunosuppressed state, including

               1. A history of solid organ or bone marrow transplantation

               2. Subjects currently receiving chemotherapy

               3. Current rheumatologic or autoimmune illness requiring treatment with
                  glucocorticoids, antimetabolite agents (methotrexate, azathioprine,
                  mercaptopurine, fluorouracil, mycophenolate, leflunomide), IMIDs (lenalidomide,
                  thalidomide, pomalidomide), calcineurin inhibitors (tacrolimus, cyclosporine),
                  mTOR inhibitors (sirolimus, everolimus), or any monoclonal antibody drugs
                  (including any drug given intravenously or subcutaneously) for the purpose of
                  immunosuppression

               4. Subjects with HIV or primary immunodeficiency syndromes
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Contradiction