Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Environmental Epidemiology of Essential Tremor

Eligibility criteria:
Inclusion Criteria:

          -  Essential Tremor

               -  Subjects must be 50 years of age or older.

               -  Subjects must have been diagnosed with Essential Tremor

               -  Subjects must live within 3 hours of UTSW

          -  Parkinson's Disease

               -  Subjects must be 50 years of age or older.

               -  Subjects must have been diagnosed with Parkinson's Disease

               -  Subjects must live within 3 hours of UTSW

          -  Healthy Individuals

               -  Healthy individuals living within 3 hours of UTSW

               -  Subjects must be 50 years of age or older

               -  You are healthy and have not being diagnosed with any neurological disease

          -  Essential Tremor and Parkinson's Disease

               -  Subjects must be 50 years of age or older.

               -  Subjects must have been diagnosed with Essential Tremor

               -  Subjects must have been diagnosed with Parkinson's Disease preceded by at least 3
                  years of enrollment in study

               -  Subjects must live within 3 hours of UTSW

        Exclusion Criteria:

          -  Healthy Individuals

               -  Subjects with medical history of neurological conditions

               -  Subjects with family history of neurological condition

               -  Subjects with spouse diagnosed with Essential Tremor or Parkinson's Disease

          -  Essential Tremor

               -  Subjects with medical history of another movement disorder such as Parkinson's
                  Disease or dystonia

               -  Subjects with head tremor that preceded hand tremor

          -  Parkinson's Disease

             --Subjects with medical history of Essential Tremor

          -  Essential Tremor and Parkinson's Disease

               -  Criteria that does not meet inclusion
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.


Eligibility (NLI label): Entailment