Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Narrow Band Imaging for Gastric Neoplasia

Eligibility criteria:
Inclusion Criteria:

          -  presenting for upper endoscopy for gastric indications

          -  gastric indications include upper abdominal pain dyspepsia abnormal gastric imaging
             iron deficiency anemia gastric ulcer management of GI blood loss without active
             bleeding reflux weight loss.

        Exclusion Criteria:

          -  Subjects who are incarcerated, younger than 18, or unable to give informed consent
             will be excluded.

          -  Patients who have evidence of active gastrointestinal bleeding will be excluded

          -  Patients taking anti-thrombotic agents including clopidogrel, ticlopidine, coumadin,
             heparin, enoxaparin, and direct II or Xa inhibitors

          -  Patients with INR >1.5, platelet count <75,000
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther Fusion

Eligibility criteria:
Inclusion Criteria:

          1. Ages 18-75

          2. Must be able to read and write in English or Spanish

          3. Must be willing to try rapid COVID-19 test and self-collect a nasal swab sample in
             both nostrils

          4. Must be one of the following:

               -  Currently experiencing a Fever of 100﮲ Fahrenheit and above or self-reports
                  having fever within the past 48 hours, and experiencing at least one (1)
                  additional associated CDC COVID-19 symptom:

                    -  Cough

                    -  Shortness of breath or difficulty breathing

                    -  Fatigue

                    -  Muscle or body aches

                    -  Headache

                    -  New loss of taste or smell

                    -  Sore throat

                    -  Congestion or runny nose

                    -  Nausea or vomiting

                    -  Diarrhea

               -  Previously tested positive for COVID-19 in past 14 days, and experiencing at
                  least one (1) additional associated CDC COVID-19 symptom

               -  Currently experiencing at least three (3) additional associated CDC COVID-19
                  symptoms so long as at least at least one (1) symptom is either: cough, shortness
                  of breath, and/or new loss of taste or smell.

        Exclusion Criteria:

          1. Currently suffering from nasal trauma such as a nosebleed

          2. Received a nasal rinse/wash/aspirates for standard of care testing
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Malic Acid in Treatment of Xerostomia

Eligibility criteria:
Inclusion Criteria:

          -  Patients with type 2 diabetes mellitus suffering from xerostomia.

          -  Patients aged between 35 and 50 years old.

          -  Glycated hemoglobin less than 7% (28) .

          -  Duration of diabetes mellitus not less than 4 years and not more than 8 years.

        Exclusion Criteria:

          -  Patients receiving any drugs that cause hyposalivation like anti-hypertensive drugs.

          -  Patients with any systemic disease reported to produce hyposalivation (sjogren's
             syndrome, hepatitis c, rheumatoid arthritis and lupus erythematosus) (8).

          -  Patients receiving chemo-therapy and radio-therapy.

          -  Mouth breathers.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 35 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Electro-Acupuncture Treatment in Patients With Osteoarthritis Of The Knee (EATOAK)

Eligibility criteria:
Inclusion Criteria:

          -  Patients of either sex with primary osteoarthritis of one or both knees fulfilling
             diagnostic criteria for osteoarthritis knee laid down by American College of
             Rheumatology.

          -  Patients also had to have a Kellgren-Lawrence (radiologic criterion) score of at least
             2 and chronic pain in the knee joint for more than 3 months.

        Exclusion Criteria:

          -  The patients with secondary osteoarthritis of knees

          -  Associated systemic arthropathies, e.g. rheumatoid arthritis and gout

          -  Patients on steroids

          -  Disease modifying drugs, e.g. methotrexate and azathioprine

          -  Patients with recent trauma in the area of acupuncture

          -  History of intra articular injection of steroid within last two months

          -  Patients missing two or more sessions of electro-acupuncture consecutively were
             excluded from the study
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 50 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 25-year-old woman comes to the clinic with her roommate.  The roommate says that the patient has twice fallen asleep while they were talking.  The patient has regularly fallen asleep in the afternoon while reading or watching television but typically feels refreshed after a brief nap.  She also reveals that she sometimes hears a voice prior to falling asleep.  She also complains of some episodes of clumsiness that cause her to drop objects or fall. MSLT showed that the sleep latency was less than 8 min and that the patient enters rapid eye movement (REM) sleep almost immediately.

Patient's own account: I brought my roommate to the clinic because she kept falling asleep when we were having a conversation. We're both 25 and usually healthy girls. She usually takes a nap in the afternoon while reading or watching TV, but usually, she is quite energetic afterward. She told me that she sometimes hears a voice before falling asleep. How weird! And sometimes she's the clumsiest! She keeps dropping all her stuff. The doctor did a sleeping test and she found out that it takes her less than 8 min to fall asleep.

Clinical trial: Validating the Use of a Subjectively Reported Sleep Vital Sign

Eligibility criteria:
Inclusion Criteria:

          -  Patients that have a scheduled office visit with their primary care physician.

          -  Patients have to be Kaiser Permanente members

        Exclusion Criteria:

          -  Non-English speaking patients unable to understand English to complete the surveys.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Mood and Behavior Changes Among Overweight Adolescent Females

Eligibility criteria:
Inclusion Criteria:

          -  Girls 10 through 14 years of age who are in good general health and have a BMI in the
             85th to 95th percentile or greater than the 95th percentile

          -  Availability of a parent or guardian to ensure the child attends all monthly clinic
             visits and who will be available to attend the monthly educational sessions if the
             child is assigned to the intervention group

        Exclusion Criteria:

          -  Cardiac or pulmonary conditions such as cystic fibrosis, congenital heart disease, or
             other conditions that would impair ability to do fitness testing

          -  Physical challenges such as deformities that would impair ability to perform physical
             activities

          -  Use of medications such as corticosteroids, seizure medication, or other central
             nervous system (CNS) medications that would interfere with daily physical activity
Female
Accepts Healthy Volunteers
Subject must be at least 10 Years old.
Subject must be at most 14 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Poster on Dysphagia-specific Food Procedures: Usability and Impact

Eligibility criteria:
Inclusion Criteria:

          -  Patients with post-acute dysphagia (lesion occurring at least six weeks prior,
             approximately),

          -  remaining in inpatient care for at least one month after the first moment of data
             collection,

          -  18 years of age or older,

          -  receiving regular visits from their family members or caregivers.

        Exclusion Criteria:

          -  Failing to meet inclusion criteria
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Laparoscopic Versus Robot-assisted Inguinal Hernia Repair: A Single Institution Randomized Controlled Trial

Eligibility criteria:
Inclusion Criteria:

          -  surgeon determined need for inguinal hernia repair

        Exclusion Criteria:

          -  < 18 years of age

          -  > 99 years of age

          -  medical indication for open repair
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Follow-up of Symptomless Inguinal and Ventral Hernias

Eligibility criteria:
Inclusion Criteria:

          -  occult inguinal or ventral hernia diagnosed in laparoscopic surgery

        Exclusion Criteria:

          -  clinically diagnosed inguinal or ventral hernia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Observational Study of Somatropin Treatment in Children

Eligibility criteria:
Inclusion Criteria:

        All participants participating in GeNeSIS must be enrolled in the core study. Participants
        for whom written consent to release information is provided may enter the core study if
        they meet any of the following inclusion guidelines:

          -  Treatment with Humatrope for improvement of growth.

          -  No treatment with somatropin in participants with a history of neoplasia or in those
             with any SHOX deficiency-related disorder.

        Exclusion Criteria:

          -  Participants with closed epiphyses are not eligible for GeNeSIS entry. However,
             participants may remain in the study if epiphyseal closure occurs during study
             participation.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: PHYSICAL ACTIVITY AND FVIII CLEARANCE: RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A (PHYSEMO)

Eligibility criteria:
Inclusion Criteria:

          -  Patients (12-60 yr. old) with severe HA under FVIII concentrates prophylaxis will be
             selected at the Haemostasis and Thrombosis Center of the Fondazione Policlinico
             Universitario "A. Gemelli", IRCCS, Rome, Italy (FPG) and at the satellite site at the
             Department of Cellular Biotechnology and Haemathology, Policlinico Umberto I, Sapienza
             University of Rome, Italy (UNSA_SS).

        Exclusion Criteria:

          -  All patients with malignant tumors, or treated with anticoagulant / antiplatelet
             agents, and suffering from other congenital coagulation disorders (von disease
             Willebrand disease, other congenital deficiency of coagulation factors) or severe
             thrombocytopenia (<30,000 Plt /μL).

        Patients who would have undergone a severe bleed or surgery during the past 3 months before
        enrolment.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Entailment