Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Sodium Pyruvate Nasal Spray Treatment of COVID-19 and Influenza Infections

Eligibility criteria:
Inclusion Criteria:

          1. Individuals with a confirmed COVID-19/influenza viral infection, as determined by a
             qualified laboratory test. A nasal swab or saliva test analyzed by qPCR for COVID19 or
             rapid flu test from nasal swab for influenza.

          2. Individuals who agree to abstain from sexual intercourse, or agree to use condoms or
             vaginal diaphragms or other devices designed to prevent contraception, during the
             entire course of the study

        Exclusion Criteria

          1. Viral infections other than COVID-19 or influenza.

          2. Clinically significant cardiac disease including uncontrolled congestive heart failure
             and unstable angina

          3. Pregnancy

          4. Females of child bearing potential age not on adequate contraception or lactating

          5. Subjects receiving systemic corticosteroid treatment within one month of Screening
             Visit

          6. Subjects Less than 18 years of age

          7. Hospitalization within last 6 months due to acute exacerbation of airway disease

          8. Subjects with a clinically significant abnormal chest x-ray within past 12 months

          9. Medication changes within one month of study entry

         10. Subjects who have participated in another investigation drug treatment study within
             the previous month.

         11. Subjects with a current history of alcohol or recreational drug abuse.

         12. Subjects who have taken dietary supplements containing pyruvate within 24 hours prior
             to the screening visit.

        Inclusion of Women and Minorities Every attempt will be made to include all genders, and
        minorities that present with an active COVID-19 or flu infection that are not exempted due
        to exclusion criteria.

        -
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Comparison of Osteoporosis Disease Management Strategies (0000-039)

Eligibility criteria:
Inclusion Criteria:

          -  Members of the Harvard Pilgrim Health Plan

        Exclusion Criteria:

          -  Individuals who are not members of the Harvard Pilgrim Health Plan
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 64 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old man comes to the office for routine checkup. He is complaining of chronic cough and occasional but progressive dyspnea.  Other medical conditions include hypertension and osteoarthritis.  The patient smokes a pack of cigarettes daily and does not use alcohol or illicit drugs.  He used to be a construction worker. On examination, there are decreased breath sounds and percussive dullness at the base of both lungs.  Chest CT scan reveals a mild bilateral pleural effusion and diffuse thickening of the pleura. The patient's documents show chronic exposure to asbestosis. The specimen of the lungs reveled  pulmonary fibrosis that is most predominant in the lower lobes, characterized  by the presence of asbestos bodies (golden-brown beaded rods with translucent centers).

Patient's own account: I'm a 47-year-old former construction worker. I'm a man and I smoke a pack of cigs a day but I don't drink or do drugs. I went to my routine checkup because I've been coughing so much lately. I also had shortness of breath and it got worse over time. I already suffer from hypertension and osteoarthritis. My doctor found that I have decreased breath sounds. I did a chest scan and it seems that I have fluid around my lungs, and the lining of my lungs has become thicker in many areas. I have been exposed a lot to asbestos fibers. The other lung exam showed that I have pulmonary fibrosis, especially in the lower part of my lungs and they found some asbestos there.

Clinical trial: Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Eligibility criteria:
Inclusion Criteria:

          -  Completion of informed consent.

          -  Adults over the age of 18.

          -  Diagnosis of IPF per ATS guidelines.

          -  Clinically stable at the time of enrollment defined as no antibiotics within the past
             month, with the exception of those patients currently listed for Lung Transplantation.

          -  No changes in immunosuppressive regimens (if applicable) over past month.

        Exclusion Criteria:

          -  Inability to understand or complete paper and pencil questionnaires.

          -  Patient not planning to return to Stanford for clinic visits.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Minimally Invasive Sweet Esophagectomy for Patients With Siewert Type II Adenocarcinoma of the Esophagogastric Junction

Eligibility criteria:
Can tolerate the cT1~3N0~1M0 phase II type II esophageal gastric junction adenocarcinoma
        patients with the corresponding operation, the past or present without radiotherapy,
        chemotherapy, nearly 5 years without any other malignant tumor history. According to the
        research design, random access to minimally invasive surgery group or traditional open
        surgery group. The follow-up procedure, if the cause of the disease or the treatment of the
        disease has been confirmed, such as the need for adjuvant chemotherapy, should be treated
        accordingly, according to the statistics appear to be accompanied by the interference to
        explain and deal with.

        Inclusion Criteria:

        A. under 70 years of age (taking into account the follow-up period); B. was performed in
        patients with cT1~3N0~1M0 type II type cTNM, C., F., D., e., and 5 years.

        Exclusion Criteria:

        I A., type III esophageal gastric junction adenocarcinoma; B. major organ function can not
        tolerate surgery; C. advanced patients.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 4-year-old boy comes to the office for the follow up of his confirmed oculocutaneous albinism.  The patient was born at 38 weeks gestation with no complications.  Vital signs are normal.  Weight and height are at the 50th percentile.  On examination, iris transillumination is present, and there are no apparent foveae on funduscopic examination.  Optic nerves are small and gray.  All the hairs including eyebrows and lashes are white.

Patient's own account: I brought my four-year-old son to his follow-up consultation for his albinism. All his hair is white, even lashes and eyebrows. My baby was born at 38 weeks pregnant with no complications whatsoever. During the consultations his vitals were normal and now his weight and height are at the 50th percentile. The doctor did an eye exam and it seems that his iris has a kind of transillumination, and there are no foveae. The doctor told me that his optic nerves are small and gray.

Clinical trial: The Effects of Lutein and Zeaxanthin Supplementation on Vision in Patients With Albinism

Eligibility criteria:
Inclusion Criteria:

          -  Age of 12 years old and older

          -  Clinical and/or genetic diagnosis of ocular or oculocutaneous albinism

          -  Ocular media allowing acceptable visualization of the retina.

          -  Ocular media allowing acceptable quality of the ocular coherence tomography (OCT)
             and/or fundus autofluorescence (FAF) scans.

          -  At least one reliable central macular pigment optical density (MPOD) measurement
             captured on the enrollment visit in at least one eligible eye

          -  Best corrected visual acuity of 20/200 or better in one or both eligible eyes (eyes
             that confirmed to be eligible by the MPOD testing).

        Exclusion Criteria:

          -  Persons taking lutein and/or zeaxanthin supplements over the past 6 months

          -  Pregnant or planning to become pregnant

          -  Evidence of present or past retinal macular condition other than congenital foveal
             hypoplasia

          -  History of gastrointestinal disease that would interfere with absorption of lutein and
             zeaxanthin

          -  Participation in a clinical trial requiring visual testing or administration of a drug
             (marketed or investigational) within 60 days before entry in the study (the day
             informed consent is signed)

          -  Inability to communicate or cooperate with the investigator due to cognitive
             impairment or poor general health

          -  Any other condition which, in the opinion of the investigators, is likely to interfere
             with the successful collection of the measures required for the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient's own account: I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Clinical trial: Light to Maximize Vision, Minimize Insomnia

Eligibility criteria:
Inclusion Criteria:

          -  Aged 55-85

          -  At least 20/200 corrected visual acuity

          -  Greater than 20° visual field with no lower visual field loss

          -  Stable health

          -  Male or female

          -  Normal color vision

          -  Normal hearing

        Exclusion Criteria:

          -  Extreme chronotype

          -  Sleep disorders

          -  Dementia

          -  Smoker

          -  Depression

          -  Alcohol abuse

          -  Use of illegal drugs

          -  Use of sleep/wake altering drugs on an acute or as needed basis (including
             nutraceuticals, antihistamines)

          -  Use of light sensitizing drugs

          -  Self-reported history of nocturia (>3 times per night)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 55 Years old.
Subject must be at most 85 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Comparison of the Laparoscopy-Assisted Distal Gastrectomy and Open Distal Gastrectomy for Advanced Gastric Cancer

Eligibility criteria:
Inclusion Criteria:

          -  Pathologic finding by gastric endoscopy: confirmed gastric adenocarcinoma

          -  Age: older than 20 year old, younger than 80 year old

          -  Cancer core: located at the middle or lower part of stomach

          -  Preoperative cancer stage (CT, GFS stage): cT2N0M0, cT2aN1M0, cT2bN1M0, cT3N0M0

          -  ASA score: ≤ 3

          -  Informed consent patients (explanation about our clinical trials is provided to the
             patients or patrons, if patient is not available)

        Exclusion Criteria:

          -  Concurrent cancer patients or patient who was treated due to other types of cancer
             before the patient was diagnosed as a gastric cancer patient

          -  Patient who was treated by other types of treatment methods, such as chemotherapy,
             immunotherapy, or radiotherapy

          -  Patient who was received upper abdominal surgery (except, laparoscopic
             cholecystectomy)

          -  Patient who was treated because of systemic inflammatory disease

          -  Pregnant patient

          -  Patient who suffer from bleeding tendency disease, such as hemophilia or patient
             taking anti-coagulant medication due to deep vein thrombosis
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient's own account: I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Clinical trial: Expanded Access Protocol of BHV-0223 for Patients With Amyotrophic Lateral Sclerosis (ALS)

Eligibility criteria:
Inclusion Criteria:

          -  Patients with diagnosed ALS of any type or duration

          -  Current or previous treatment with oral riluzole tablets, or patients who have never
             taken riluzole oral tablets, or patients who have successfully completed a clinical
             trial with BHV-0223 and were not withdrawn prematurely due to adverse events

          -  Swallowing difficulties, or patient or caregiver report choking one or more times per
             week, or investigator deems appropriate to treat with sublingual BHV-0223 because
             (s)he deems the patient cannot be satisfactorily treated with Rilutek®

          -  Adequate hepatic function

        Exclusion Criteria:

          -  Patient with history of severe hypersensitivity reaction to riluzole oral tablets or
             BHV-0223

          -  Patient is known to have any other acute or chronic liver disease
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Comparison of Postoperative Inguinal Pain Between the Onstep Technique and the Lichtenstein Technique

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of unilateral inguinal hernia.

          -  Male or Female.

          -  Older tan 16 years.

          -  Accept to participate in the study.

        Exclusion Criteria:

          -  Chronic Obstructive Pulmonary Disease.

          -  Obesity.

          -  Diabetes Mellitus.

          -  Cirrhosis.

          -  Diseases involving collagen deficiency.

          -  Previous surgery in the groin.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Laparoscopic Inguinal Hernia Repair in Infancy and Childhood

Eligibility criteria:
Inclusion Criteria:

        Bilateral congenital inguinal hernia (CIH), recurrent cases, unilateral cases with
        questionable other side, parental request and cases with CIH associated with umbilical
        hernia.

        Exclusion Criteria:

        Hernia of canal of Nuck in females, Inguinal hernia with undescended testis, Parental
        refusal, Contraindications for laparoscopy as lower major abdominal surgery
Male
No healthy subjects accepted to join the trial.
Subject must be at least 6 Months old.
Subject must be at most 3 Years

Eligibility (NLI label): Contradiction