Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Enhanced Triage for COVID-19

Eligibility criteria:
Inclusion Criteria:

          -  Patients presenting with clinical suspicion of COVID-19 infection, as per UHN case
             definition at the time of presentation

          -  Age >18 years

          -  Ability to provide verbal informed consent

        Exclusion Criteria:

          -  Patients who are not suspected of COVID-19 infection, as per UHN definition at the
             time of presentation
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Trastuzumab to Patients With Advanced Gastric Cancer With HER2 Positive Expression in CTC

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 or over

          -  Histological diagnosis of recurrent or metastatic gastric cancer

          -  Immunohistochemistry (IHC 0 or 1+) or FISH negative (if IHQ 2+) for HER2 on tissue
             biopsy, according to institutional routine

          -  Candidates to initiate first-line palliative treatment; Previous adjuvant treatment is
             allowed since its termination occurred at least 12 months ago

          -  ECOG performance range 0 to 2

          -  Informed consent form signed by patient or legal representative

        Exclusion Criteria:

          -  Patients already on or previously using anti-HER2 therapy

          -  Left ventricular ejection fraction (LVEF) <55% baseline, as already evaluated in the
             gastric cancer routine

          -  Pregnant or lactating women

          -  Patients participating in other experimental drug protocols

          -  Patients who received previous palliative chemotherapy

          -  Another synchronic neoplasia requiring systemic treatment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: The Turkish Oropharyngeal Dysphagia Screening Test for Patients and Professionals

Eligibility criteria:
Inclusion Criteria:

          -  Willing to participate

          -  Having swallowing problems

        Exclusion Criteria:

          -  Being under the age of 20 years, and above the age of 60 years

          -  Not willing to participate

          -  No swallowing problems
Male
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient's own account: I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Clinical trial: Pacemaker Effect With Closed Loop Sensor in Neuromodulated Syncope Refractory to Medical Therapy

Eligibility criteria:
Inclusion Criteria:

          -  Over 18 years.

          -  Diagnosis of neurally mediated syncope with a tilting table test (Tilt test) that
             demonstrates a mixed (type 1) or cardioinhibitory response (Type 2A and 2B).

          -  Negative impact on work and social life.

          -  Non-respondent to pharmacological therapy (Fludrocortisone 0.1mg / 24 hours for 3
             months) and non-pharmacological (exercise, hydration and consumption of more than 3
             months) is due to a cardiologist who has performed a strict stricture over time.

          -  At least 2 episodes of syncope in the last year.

        Exclusion Criteria:

          -  Complete atrioventricular block.

          -  Second degree ventricular atrial block.

          -  Bradycardia syndrome - tachycardia.

          -  Disease of the sinus node.

          -  Arrhythmia (bradycardia or tachycardia that generate syncope and / or low cardiac
             output).

          -  Syncope due to hypersensitivity of the carotid sinus.

          -  Syncope with Tilt Test that demonstrates depressant vasopressor response (type 3).

          -  Refusal of the patient, his relatives or the attending physician to participate in the
             study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: An Attempt to Find Out Root Cause of a Pain Producing Knee Disease

Eligibility criteria:
Inclusion Criteria:

          -  Age =>30 years

          -  Knee pain which appeared without any apparent cause, exacerbated by exertion and
             subsided by rest.

          -  Presence of limited morning stiffness

          -  No history of infection, inflammation or trauma to rule out secondary OA

          -  Disability in sitting, climbing stairs or walking

        Exclusion Criteria:

          -  Backache

          -  Leg pain (e.g. sciatica)

          -  Inability to lie supine (e.g. kyphosis)

          -  Inability to lie prone (e.g. central obesity)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring

Eligibility criteria:
Inclusion Criteria:

          -  All patients who presented to GI Motility Lab at IU University Hospital for esophageal
             manometry-impedance and/or EndoFLIP

        Exclusion Criteria:

          -  Age <18 yrs old

          -  Unable to communicate verbally with the staff
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old man comes to the clinic for the follow up of his neuromuscular disease. He experienced gradual, progressive weakness of the left upper extremity over the last year.  Over the last few months, he has also noticed weakness in the right upper extremity.  BP is 120/75, PR is 80 and temperature is 37 C. Reflexes are brisk in the upper extremities, and the plantar responses are extensor.  Mild gait ataxia is present. The patient is under treatment of Riluzole 50 mg BID with the diagnosis of ALS.

Patient's own account: I've been suffering from a neuromuscular disease for a while now, and I went to my doctor's office. I'm now a 47-year-old man and over the past year I experienced a progressive and gradual weakness of my left upper extremity, and over the past month, I also noticed a weakness over my right upper extremity. My heart rate was 120/75, and my  PR was 80 with 37°C for temperature. My reflexes are not good in my upper extremities, and I have trouble with my balance. I'm also under Exservan 50 mg for my sclerosis.

Clinical trial: EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS)

Eligibility criteria:
Inclusion Criteria:

        Medical Subjects:

          -  Be able to give consent themselves or via a legally authorized representative.

          -  Diagnosed with a neuromuscular disease and have limited ability to communicate.

          -  Be able to see visual cues such as targets or letters presented on the screen, and/or
             ability to hear auditory cues such as tones or words presented through speakers or
             earphones.

          -  Be able to understand and remember instructions concerning participation.

        Healthy control subjects:

          -  Be able to consent to give consent themselves or via a legally authorized
             representative.

          -  Be able to see visual cues such as targets or letters presented on the screen, and/or
             ability to hear auditory cues such as tones or words presented through speakers or
             earphones.

          -  Be able to understand and remember instructions concerning participation.

        Exclusion Criteria:

          -  Individuals with cognitive impairments that would impact their ability to follow the
             instructions
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: PT-led Triage for Patients With Hip o Knee Osteoarthritis

Eligibility criteria:
Inclusion Criteria:

          -  Referred to Sahlgrenska University hospital

          -  Primary osteoarthritis in the hip or knee

          -  Understanding and speaking Swedish

        Exclusion Criteria:

          -  Prior assessment by and referral from an orthopedic surgeon for the current problem

          -  Secondary osteoarthritis (posttraumatic osteoarthritis, femoral head necrosis), when
             stated on the referral

          -  Referred to a specific surgeon
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 51-year-old man comes to the office complaining of fatigue and some sexual problems including lack of libido. The patient doesn't smoke or use any illicit drug.  Blood pressure is 120/80 mm Hg and pulse is 70/min.  Oxygen saturation is 99% on room air.  BMI is 24 kg/m2.  Skin examination shows increased pigmentation. Genotype testing is consistent with homozygosity for the C282Y mutation. Laboratory study shows transferrin saturation of 55% and serum ferritin of 550 μg/L. He is diagnosed as a case of hemochromatosis.

Patient's own account: I am 51 years old and I just came back from the doctor's office. I'm sick and tired of being that exhausted, reaching the point where me and my lovely wife are not touching each other anymore! I'm not smoking or doing drugs! My blood pressure was 120/80 mm Hg, and pulse was 70/min and my oxygen saturation 99%. My BMI is 24. My skin also turned a bit darker lately. He tested my genes and told me that I have a mutation of the C282Y gene. I also did lab tests where my transferrin saturation was 55% and serum ferritin was 550  μg/L. The doctor diagnosed me with iron overload.

Clinical trial: Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent Patients

Eligibility criteria:
Inclusion Criteria:

          -  Iron overloaded male or female patients with primary or secondary hemochromatosis

          -  Age: 4 years and older

          -  Patients with desferrioxamine toxicity or allergy (e.g. visual or hearing defects,
             bone abnormalities, reactions at injection site)

          -  Patients unable or unwilling to comply satisfactorily with regular desferrioxamine
             administration on 5-7 days/week

          -  Combination treatment: patients not sufficiently chelated with desferrioxamine or
             deferiprone monotherapy

          -  Patients must be willing to undergo routine screening including medical history,
             physical examination and hematology, biochemistry and other laboratory tests

          -  Written informed consent

        Exclusion Criteria:

          -  Children under 4 years of age

          -  Female and male of reproductive age, sexually active but not taking adequate
             contraceptive precaution

          -  Woman who are pregnant or breast-feeding

          -  Patients with HIV

          -  Patients with active hepatitis requiring treatment

          -  Patients with severe hepatic failure, cirrhosis

          -  Patients with neutropenia (neutrophils less than 1.5 exp9/l, MDS: less than 0.5
             exp9/l)

          -  Patients with thrombocytopenia (platelets less than 100 exp9/l, MDS: less than 20
             exp9/l)

          -  Patients with decompensated heart failure (LVEF less than 40% or patients under
             continuous cardiac medication)

          -  Patients with severe renal failure
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer

Eligibility criteria:
Inclusion Criteria:

          1. Early gastric cancer with biopsy confirmed high grade dysplasia or adenocarcinoma
             (intestinal type)

          2. Preoperative investigation with magnifying endoscopy and / or EUS predicted to be
             mucosal lesion

          3. Any tumor size if the early gastric cancer has no ulceration

          4. Tumor size ≤ 3cm if the early gastric cancer has ulceration

        Exclusion Criteria:

          1. Gastric cancer with preoperative magnifying endoscopy and / or EUS predicted to beyond
             submucosal invasion

          2. Poorly differentiated or signet ring cell adenocarcinoma

          3. Age > 80 or < 16

          4. Pregnancy

          5. ASA > IV
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Contradiction