Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 67-year-old man comes to the clinic with slowly worsening vision in both eyes.  He is not able to drive at night, as the symptoms are worse at night. His pupils are normal in diameter both in the light and darkness. Other medical history is unremarkable.  Ocular examination shows loss of the red reflex and blurry vision.  Acuity testing shows 50/100 vision in both eyes with normal visual field testing. His blood pressure is 130/70 and pulse is 68/min. the other physical examinations are normal.

Patient's own account: I am a 67 years-old man, and I haven't been able to drive at night due to my vision getting worse. My vision is not the best in general, but night makes it even worse. The ophthalmologist told me that my pupils were normal. However, I have slow reflexes and blurry vision. My acuity test came back with 50/100 vision in both of my eyes. They also took my blood pressure, which was 130/70 with a 68 pulse. My other exams came back just fine.

Clinical trial: Visual and Functional Assessment in Low Vision Patients

Eligibility criteria:
Inclusion Criteria:

          -  Snellen VA or equivalent ≤ 6/60 in both eyes

          -  Patient has capacity to give consent and to undertake vision tests

        Exclusion Criteria:

          -  Diagnosis of functional vision loss

          -  Unwilling and/or unable to sign informed consent and complete the vision tests
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Study of CT and MR in the Gastric Cancer

Eligibility criteria:
Inclusion Criteria:

          1. Consecutive patients with preoperative pathologically con-firmed gastric cancer by
             endoscopy and preoperative imaging data (esophagography\CT\EUS\MRI) were included.

          2. No contraindications for MRI examination. No contraindications contrast.

          3. The patients participate in this study with informed consent.

        Exclusion Criteria:

          1. The patients couldn't performed MSCT or MR scanning or artefacts affect the
             evaluation.

          2. The patients are extremely anxious and uncooperative about surgery or neoadjuvant
             therapy .

          3. PatientsThe patients refuse to participate in the project.

          4. Other situations considered by investigators not meet the inclusion criteria.
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Eye Dryness Evaluation in Primary Sjögren's Syndrome

Eligibility criteria:
Inclusion Criteria:

          -  diagnosis of pSS according to ACR/EULAR classification criteria

        Exclusion Criteria:

          -  patient does not possess a smartphone with web connection

          -  patient unable to sign an informed consent
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: Mindfulness for Osteoarthritis-related Knee Pain

Eligibility criteria:
Inclusion Criteria:

          -  Adults over 18 years, there is no upper age limit.

          -  Osteoarthritis of the knee (defined as joint space narrowing and osteophytes in 1 or
             more compartment) and moderate to severe knee pain (defined as 40-80mm on a 100mm
             visual analogue scale).

        Or

          -  Persistent moderate to severe knee pain (40 - 80mm on a 100mm visual analogue scale),
             one year following total knee replacement

        Exclusion Criteria:

          -  People who have previously participated in a 8 week Mindfulness course

          -  Terminal illness and other conditions leading to incapacity to participate in the
             study

          -  Acute knee injury, knee joint surgery or steroid injection to the knee within previous
             3 months or currently on a waiting list for knee joint surgery

          -  Inflammatory arthritis (eg Rheumatoid arthritis or psoriatic arthritis)

          -  Patients who are unable to provide informed consent

          -  Patients who are unable to communicate in English, as the intervention is delivered in
             English
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures

Eligibility criteria:
Inclusion Criteria:

          -  Adult > 18 years of age

          -  Closed fracture

          -  Isolated injury

          -  No prior injury to ipsilateral forearm

          -  Less than or equal to two attempts at reduction

        Exclusion Criteria:

          -  Ipsilateral upper extremity injury

          -  Open injury or neurovascular compromise

          -  Greater than two attempts at reduction

          -  Presentation greater than 24 hours after injury
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Cervical Priming With Misoprostol Prior to Operative Hysteroscopy

Eligibility criteria:
Inclusion Criteria:

          -  Symptomatic patients that were suspected as having intrauterine pathology such as
             submucosal myoma, endometrial polyps or other endometrial pathological findings based
             on the transvaginal ultrasound were enrolled.

          -  women who are more than 20 years of age with having sexual contact history

          -  women whose last menstrual period are within the last two months.

        Exclusion Criteria:

          -  Post menopausal women

          -  any evidence of a contraindication or allergy to PGs

          -  any sign of genital infection, history of cervical surgery, endometrial lesions with
             suspected endo- or exocervical lesions that could affect the cervical resistance or
             patients that were not candidates for surgery.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Efficacy of Acupuncture on Chronic Pelvic Pain in Women With Endometriosis or Adenomyosis

Eligibility criteria:
Inclusion Criteria:

          -  Patients diagnosed pathologically of Endometriosis or Adenomyosis among those who had
             undergone laparoscopic surgery due to pelvic pain

          -  Patients who have been on GnRH agonist treatment for 6 months after being diagnosed
             Endometriosis or Adenomyosis

          -  Patients who agreed a written consent by their own will

          -  Patients' compliance and geographical adjacency appropriate for proper follow up
             survey

          -  continuous pelvic pain over VAS 5 during past 1 week on screening visit(after 6 weeks
             of surgery) (0='no pain', '10=most severe')

        Exclusion Criteria:

          -  Those who had taken hormones or drugs that can affect diagnosis of endometriosis or
             adenomyosis for past 1 year

          -  Patients found to have malignant tumor of uterus and adenexa, PID or pregnancy during
             surgery

          -  Allergies to metal or contraindications for acupuncture treatment (ex: coagulopathy,
             epilepsy)

          -  Unable to participate in clinical trial by doctor's judgment

          -  irritable bowel syndrome
Female
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient's own account: I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Clinical trial: Hypersensitive Troponin Performance to Identify Syncope at Risk of Serious Adverse Events in the Short Term

Eligibility criteria:
Inclusion Criteria:

          -  Patients admitted to the emergency department for syncope as defined by European
             Society of Cardiology (ESC) recommendations.

        Exclusion Criteria:

          -  Patient under guardianship or safeguard of justice

          -  Refusal to participate

          -  Inability to contact the patient again at M1, M3, M6

          -  Malaise without loss of consciousness (lipothymia)

          -  Loss of post-traumatic knowledge (after head trauma)

          -  Loss of consciousness of toxic origin

          -  Loss of consciousness of confirmed epileptic origin (known epileptic or strongly
             evocative history with post-critical state)

          -  Diagnosis performed during the initial emergency assessment of a major adverse
             cardiovascular event.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Vitamin Gum Pharmacokinetics

Eligibility criteria:
Inclusion Criteria:

          1. Men or women aged 18 - 60 yrs old in generally good health.

          2. Healthy oral cavity with no pre-existing oral diseases including cancer,
             periodontitis, or mucositis.

          3. No chewing or swallowing disorders.

          4. No known clotting disorders.

          5. Willingness to follow the investigator instructions and requirements of the protocol.

          6. Ability to give consent.

          7. Proficiency with the English language (both written and verbal)

        Exclusion Criteria:

          1. Pre-existing oral diseases including oral cancer, periodontitis, or mucositis.

          2. Chewing or swallowing disorder.

          3. Iron deficiency or anemia. The level of deficiency needed for exclusion will be at the
             discretion of the CRC physician associated with the study.

          4. Pregnant, lactating, or planning to become pregnant during the study.

          5. Phenylketonuric

          6. Medical, social, or economic circumstance which is likely to prevent adherence to the
             protocol.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of COVID-19 based on either ground glass appearance in chest CT scan or
             positive RT-PCR test for COVID-19

          -  Oxygen saturation drop below 93%

          -  Systolic blood pressure drop below 100 or blood pressure drop of 30 mm Hg from the
             patient's previous normal systolic blood pressure

          -  Fever

          -  Dry cough

          -  Positive PCR for COVID-19

          -  Laboratory indices include CRP and ESR indicating COVID-19

        Exclusion Criteria:

          -  Patient dissatisfaction

          -  Existence of drug interactions

          -  Lack of proper conditions for receiving medication
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 16 Years old.
Subject must be at most 100 Years

Eligibility (NLI label): Contradiction