Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Validation of the Turkish Version of QUALEFFO-31

Eligibility criteria:
Inclusion Criteria:

          -  To have Dual-energy X-ray absorptiometry (DXA) results and thoracolumbar lateral spine
             X-Rays taken for any reason in the last 6 months.

          -  To have calcium, phosphorus, parathormone (PTH) and 25-hydroxyvitamin D level in the
             last 3 months.

          -  To be independently ambulatory.

          -  To have a cognitive capacity to understand and complete the questionnaires.

        Exclusion Criteria:

          -  To have malignancy.

          -  To have inflammatory diseases.

          -  To have a metabolic bone disease other than osteoporosis.

          -  To have neuromuscular diseases.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Pilot Study of Non-exposure Simple Suturing EFTR With Sentinel Lymph Node Navigation for EGC (Senorita3-pilot)

Eligibility criteria:
Inclusion Criteria:

          -  single lesion of adenocarcinoma in preoperative endoscopic biopsy

          -  clinical stage T1N0 in the preoperative evaluation of endoscopy and computed
             tomography

          -  tumor size: less than 3cm in differentiated type, less than 2cm in undifferentiated
             type

          -  location: 2cm far from the pylorus or cardia

          -  aged 20 to 80

          -  ECOG 0 or 1

          -  patient who signed the agreement

          -  patient who is suspected to underwent laparoscopy assisted gastrectomy

        Exclusion Criteria:

          -  indication of endoscopic submucosal resection

          -  inoperable due to poor cardiac, pulmonary function

          -  pregnant

          -  having allergic reaction, previous upper abdominal surgery except laparoscopic
             cholecystectomy, previous radiation therapy to upper abdomen

          -  diagnosed as malignancy within 5 years except carcinoma in situ of cervix cancer and
             thyroid cancer
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: The Turkish Deglutition Handicap Index

Eligibility criteria:
Inclusion Criteria:

          -  Willing to participate

          -  Having swallowing problems

        Exclusion Criteria:

          -  Being under the age of 20 years, and above the age of 60 years

          -  Not willing to participate

          -  Having no swallowing problems
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Staccato Loxapine PK in Smokers and Nonsmokers

Eligibility criteria:
Inclusion Criteria:

          -  Normal spirometry at screening and in good general health as determined by a complete
             medical history, physical examination, 12-lead ECG, blood chemistry profile,
             hematology, and urinalysis,

          -  Smokers must have a history of smoking > 15 cigarettes/day currently and for at least
             the last 2 years,

          -  Nonsmokers must have never smoked > 5 cigarettes/day and not smoking at all for at
             least the last 2 years.

        Exclusion Criteria:

          -  Any acute illness in the 5 days,

          -  Use of a bronchodilator for the treatment of wheezing within 12 months, OR

          -  Any other disease or condition, by history, physical examination, or laboratory
             abnormalities that would present undue risk to the subject, or may confound the
             interpretation of study results.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair

Eligibility criteria:
Inclusion Criteria:

        Age: 21- 80 yrs

          -  Informed consent

          -  Diagnosis of Hernia

          -  ASA I and II

          -  BMI<25.

        Exclusion Criteria:

        Bleeding disorders

          -  Age below 21

          -  Strangulated Hernia

          -  BMI > 30

          -  Incarcerated and obstructed hernia

          -  Recurrent hernia

          -  Bilateral hernia

          -  Previous LSCS

          -  Previous lower abdominal surgery
Male
No healthy subjects accepted to join the trial.
Subject must be at least 21 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: The Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Moderate COVID-19

Eligibility criteria:
Key Inclusion Criteria:

          1. Over 19 years of age

          2. COVID-19 confirmed by a real-time RT-PCR tests 4 days prior to clinical trial
             enrollment

          3. Patients with peripheral capillary oxygen saturation (SPO2) greater than 94% at the
             time of screening

          4. Patients whose body temperature is measured according to the measured area without
             taking a fever reducer during screening:

             [armpit of greater than 37.0 °C or an oral of greater than 37.2 °C; Patients with
             rectum greater than 37.6 °C or eardrum greater than 37.5 °C] (Notes: Although you take
             a fever reducer, you can still be enrolled in after investigator's judgement whether
             there is fever or not.)

          5. Patients with evidence of lung invasions as a result of radiation tests

        Exclusion Criteria:

          1. Patients who need breathing device (for example, Invasive ventilation, Invasive
             mechanical ventilation, Extra-corporeal membrane oxygenation).

          2. Patients who participated in other clinical trials related to COVID-19.

          3. Patients who were administered drugs directly to COVID-19 24 hours prior to the start
             of the study.

          4. Patients whose AST or ALT has increased by more than 5 times the normal lab value.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 19 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: Digestive Events in Duchenne Muscular Dystrophy Patients

Eligibility criteria:
Inclusion Criteria:

          -  all Duchenne muscular dystrophy patients in our center

        Exclusion Criteria:

          -  none
Male

Subject must be at least 15 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Economic Assessment of STarting Endoscopic Robotic Groin Hernia Repair

Eligibility criteria:
Inclusion Criteria:

          -  adult patients

          -  underwent uni-or bilateral groin hernia repair in the period 2015- 2019

          -  surgery through minimal invasive repair

        Exclusion Criteria:

          -  open surgery or conversion from minimal-invasive to open surgery

          -  combined procedures

          -  age below 18 years
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Computerized Evaluation of the Endometrial Myometrial Junction During a Natural Menstrual Cyle.

Eligibility criteria:
Inclusion Criteria:patients with regular menstrual cycles -

        Exclusion Criteria:patients on contraceptive pills.patients after uterine surgery

        -
Female
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Virtual Reality for Osteoarthritis Knee Pain Pilot

Eligibility criteria:
Inclusion Criteria:

          -  Must be 18-85 years old

          -  Have a clinical diagnosis of OA of the knee

          -  Be able to read and write English

        Exclusion Criteria:

          -  Can't have rheumatoid arthritis, fibromyalgia, or other chronic pain condition.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: 3D HD Versus 2D HD in Laparoscopic Inguinal Hernia Repair: a Randomized Controlled Trial

Eligibility criteria:
Inclusion Criteria:

          -  Patients scheduled for elective inguinal hernia repair (out-patient treatment)

        Exclusion Criteria:

          -  Previous lower abdominal surgery

          -  ASA-score 3 or above
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 85 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: MOTHIF II : THERAPEUTIC MANAGEMENT AND USE OF CLOTTING FACTORS IN HEMOPHILIA A & B IN FRANCE II

Eligibility criteria:
Inclusion Criteria:

          -  All patients hemophiliac A or B, with or without inhibitors, included in the Nhemo (7
             centres) and the Behrlingo database, treated with factor 8 or factor 9 products or
             by-passing agents

          -  All Hemophilia A or B patients of any severity without inhibitors, included in the
             NHEMO database and the BEHRLINGO database, without any treatment by clotting factors

          -  All Hemophilia A or B patients having given consent to be included in the study (2
             times 12 months), during their usual follow-up (consultation…). For the other
             patients, a derogation from the obligation to inform the patients will be made to the
             CNIL.

        Exclusion Criteria:

          -  patients under guardianship
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment