Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Comparative Study of Epigastric Pain Syndrome and Postprandial Distress Syndrome

Eligibility criteria:
Inclusion Criteria:

          -  aged greater than 20 years

          -  fulfill Rome III diagnostic criteria

        Exclusion Criteria:

          -  children and teenagers aged less than 20 years

          -  Organic lesions such as ulcers, tumors, bleeding, vasculopathy or esophagitis as
             demonstrated on upper endoscopy

          -  concurrent illness with malignancy, diabetes mellitus, liver cirrhosis, renal failure
             or porphyria

          -  diagnosis of organic disease for dyspeptic symptoms by treating physicians

          -  history of abdominal surgery

          -  concurrent user of aspirin and NSAID

          -  history of allergy or severe side effects to lansoparzole

          -  pregnant or lactating women
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle

Eligibility criteria:
Inclusion Criteria:

          -  Eligible patients will include anyone >18 years old that presents to the participating
             clinical institutions and requires an endosonographic evaluation for the presence of a
             solid-appearing mass lesion amenable to EUS access, and no contraindication to FNA as
             determined by standard clinical care

        Exclusion Criteria:

          1. Refusal to participate in the study

          2. Solid-appearing mass lesion that in not amenable to EUS guided needle access for
             tissue acquisition

          3. Patients with incomplete medical records

          4. Pregnant patients

          5. Prisoners

          6. INR > 1.5

          7. Platelets < 50,000
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: World Bleeding Disorders Registry

Eligibility criteria:
Inclusion Criteria:

          -  Patients of participating Hemophilia Treatment Centres with Hemophilia A or B

        Exclusion Criteria:

          -  none
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: The Effect of Structured Information and Individually Adapted Exercise on Levels of Physical Activity Measured by Accelerometer in Patients With Knee or Hip Osteoarthritis

Eligibility criteria:
Inclusion Criteria:

          1. Age between 18 and 75 years old.

          2. Patients with clinically verified OA, coming to see a physical therapist for the
             Supported self-management of osteoarthritis program.

        Exclusion Criteria:

          1. Other serious disorders causing hip or knee pain (e.g. tumor, rheumatic arthritis,
             sequel hip fracture).

          2. Other symptoms more aggravating than the OA problem (e.g. chronic pain, fibromyalgia,
             cardio-respiratory dysfunction, spinal condition).

          3. Total joint replacement surgery within the past 12 months.

          4. Other surgery of knee or hip within the past 3 months.

          5. Unable to read and understand Swedish and follow verbal and visual instructions.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Nutrition and Soccer for Pediatric Overweight and Obesity

Eligibility criteria:
Inclusion Criteria:

          -  obese or overweight 4th grade public school student in Starkville

        Exclusion Criteria:

          -  unable to run or physical disease or disability
Female
Accepts Healthy Volunteers
Subject must be at least 9 Years old.
Subject must be at most 12 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Omepral® Tablets Special Clinical Experience Investigation in Patients With Erosive Esophagitis

Eligibility criteria:
Inclusion Criteria:

          -  Patients newly diagnosed as erosive esophagitis or history of erosive esophagitis
             confirmed by endoscopy.

          -  Patients who answered questionnaires of quality of life (QOLRAD-J), symptom severity
             and frequency and treatment satisfaction.

          -  During the past 1 week , patients who have either two days or more with heartburn or
             acid taste in the mouth of any severity

        Exclusion Criteria:

          -  Patients receiving treatment with proton pump inhibitors, which make stomach acid
             decreased during the last 4 weeks prior to enrolment.

          -  Patients who cannot answer questionnaires of quality of life (QOLRAD-J), symptom
             severity and frequency and treatment satisfaction.

          -  Patients included previously in this study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)

Eligibility criteria:
Diagnosis and main criteria for inclusion:

          -  Subjects diagnosed with GERD with symptomatic improvement on PPIs.

          -  Subjects who have demonstrated a baseline 24 Hour pH ≥ 4% time with pH ≤ 4.0.

          -  Subjects with a baseline GERD-HRQL heartburn score of ≤11 on PPI and ≥ 20 off PPI.

        Diagnosis and main criteria for exclusion:

          -  Extensive Barrett's Esophagus (> 2 cm).

          -  Esophagitis (LA Classification Grades C or D).

          -  Previous history of gastroesophageal surgery, anti-reflux procedures, or
             gastroesophageal or gastric cancer.

          -  Large hiatal hernia (> 3 cm).

          -  Current complaints of clinical dysphagia evidenced by greater than one occurrence per
             month.

          -  Esophageal strictures

          -  Esophageal or gastric varices
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Inguinal Hernia and Arterial Disease

Eligibility criteria:
Inclusion Criteria:

          -  patients with inguinal hernia

        Exclusion Criteria:

          -  patients with malignancies
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 50-year-old woman comes to the clinic with intermittent ear discharge and sense of hearing loss on her left ear.  Past medical history is significant for obesity, hyperlipidemia, and diabetes mellitus.  Her medications include Metformin, Atorvastatin and Vit D supplement. Vital signs are normal. BMI is 37. Otoscopy shows a small perforation in the left tympanic membrane and a pearly mass behind the membrane.  Conduction hearing loss is noted in the left ear.  The remainder of the ear, nose, and throat examination is normal.

Patient's own account: I went to the clinic the other day because I had some fluid in my ear and I felt like I could not hear as well as I used to in my left ear. I'm a 50-year-old woman, and I have been obese for a while now. I have diabetes and cholesterol. I take some medication. I take metformin, atorvastatin, and vitamin D supplements. When I was admitted, my vitals were normal. My BMI is 37. When they looked into my ears, they said that my left tympanic membrane was broken and there was some fluid behind the membrane. During the hearing test, they could assess that my left ear suffers from hearing loss. They also performed ear, nose, and throat examinations that turned out to be normal.

Clinical trial: Study of Lipid Control in Hyperlipidemic Participants (MK-0653-179)

Eligibility criteria:
Inclusion criteria:

          -  Hyperlipidemic

          -  On therapy for hyperlipidemia for >=3 months without achieving target lipid values

        Exclusion criteria:

          -  Hypersensitivity or intolerance to hypolipemics

          -  Significant myopathy or rhabdomiolysis probably caused by hypolipemics

          -  Uncontrolled endocrine or metabolic disease which is known to affect lipid or
             lipoprotein values (for example, hypothyroidism and hyperthyroidism)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 30 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI

Eligibility criteria:
Inclusion Criteria:

          1. PCOS diagnosed by Roterdam criteria

          2. Protocol used for ovulation induction either long procol with freeze all embryos vs
             antagonist with fresh embryo transfer

          3. BMI less than 30

          4. ALL patients receiving adjuvant drugs for prevention of OHSS in the form of metformin,
             cabergoline as well as prophylactic hysteril , low dose asprin and LMW heparin
             following oocyte retrieval on a routine basis

        Exclusion criteria;

          1. PCOS on long protocol with fresh embryo transfer and those on antagonist protocol with
             freezing all embryo

          2. BMI more than 30

          3. PCOS patients not given adjuvant drugs in prophylaxis of OHSS

          4. Antagonist cases receiving agonist as trigger instead of HCG

          5. PCOS receiving more than 5000 IU HCG as trigger

          6. PCOS undergoing costing during ovulation induction

          7. PCOS with known medial problems as diabetes or hypertension
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 39 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: A New Method of Muscle Strength Testing Using a Quantitative Ultrasonic Technique and a Convolutional Neural Network

Eligibility criteria:
Inclusion Criteria:

          -  no major complaints of muscle numbness, spasm, or atrophy, muscle-related physical
             activity impairment or joint swelling and pain

          -  no obvious malformation in the lower limbs

          -  no disease history in the musculoskeletal system, nervous system, and peripheral
             blood,

          -  no history of severe trauma in the lower limbs

          -  joint mobility and muscle tension met the thresholds of muscle strength assessments

          -  no severe osteoporosis

          -  no acute inflammation or acute bone fracture repair

          -  between 18-55 years of age

        Exclusion Criteria:

        -
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Contradiction