Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 23-year-old man comes to the emergency department following an episode of syncope.  He was working out when he felt dizzy and passed out without head injury.  He has had 3 other episodes of light-headedness over the last year, all happening during physical activity. He never had this experience while resting. He has no other medical conditions.  The patient does not use tobacco, alcohol, or illicit drugs.  His father died suddenly at age 35.  Vital signs are within normal limits.  On physical examination, the patient has a harsh systolic murmur.  The lungs are clear with no peripheral edema. Echocardiography shows asymmetric interventricular septal hypertrophy.

Patient's own account: I'm 23, and I got admitted to the ER because I fainted all of a sudden. I was in the gym, working out, when all of a sudden, I just got dizzy and passed out. Hopefully, I didn't hit my head. It's not my first time having that kind of dizziness at the gym, never when I'm chilling at home tho. I don't have any special medical conditions and I'm not even smoking, drinking or doing drugs! My dad died suddenly when he was 35, so I'm kind of scared. My vitals were normal while at the ER and they did a physical exam and they told me my heart sounds abnormal. My lungs are ok, but I had to do an echography of my heart, and they told me it is bigger than average.

Clinical trial: Prevalence of Pulmonary Embolism in Patients With Syncope

Eligibility criteria:
Inclusion Criteria:

          -  first episode of syncope

        Exclusion Criteria:

          -  previous episodes of syncope

          -  ongoing anticoagulation

          -  age younger than 18 years

          -  pregnancy
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Mifepristone and Misoprostol for Fetal Demise

Eligibility criteria:
Inclusion Criteria: healthy hemodynamically stable females with a non-viable pregnancy

        -

        Exclusion Criteria:

          -  orthostatic hypotension, contraindication to either mifepristone or misoprostol,
             treatment during current pregnancy to provide surgical or medical evacuation of the
             uterus, evidence of ovarian hyperstimulation syndrome, known or suspected pelvic
             infection,known or suspected clotting defect or receiving anticoagulants,
             cardiovascular disease, current breastfeeding, pregnancy with and IUD in situ, current
             participation in another clinical trial, prior participation in this trial, suspected
             or confirmed endometrial AV malformation, clinical indication requiring the
             karyotyping of products of conception
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 24-year-old man comes to the office complaining of infertility.  He and his wife have been trying to conceive for the last 18 months.  Medical records of his wife showed no abnormalities.  The patient doesn't smoke and takes no medications.  Height is 185 cm and weight is 77 kg.  Heart and lung sounds are normal.  There is bilateral gynecomastia and bilateral descended firm testes.  The lower extremities appear abnormally long. His karyotype evaluation shows 47, XXY consistent with Klinefelter syndrome.

Patient's own account: I'm only a 24 year old man but I’m already struggling with infertility. I went to a clinic with my wife the other day because we've been trying to have a baby for at least 18 months. The medical records of my wife are totally normal. For me I don't smoke or take any medication. I'm 185 cm and 77 kg. Everything was normal when the doctor inspected my lungs and my heart. The doctor said that I have enlarged breasts for a man. My testicles seem normal. The doctor noticed that my legs were abnormally long compared to the rest of my body. I also had a karyotype evaluation which led the doctor to diagnose me with Klinefelter syndrome.

Clinical trial: The Impact of a Nutritional Supplement (Impryl®) on Male Fertility

Eligibility criteria:
Inclusion Criteria:

        Couples with failure to conceive for at least 12 months and starting with EM or Couples
        starting with 1st/ 2nd/3rd cycle of IUI (with/without ovarian stimulation) or Couples
        starting with 1st/ 2nd/3rd cycle of IVF/ICSI

        Furthermore:

          -  Male with age 18-50 years

          -  Female partner with age 18-43 years

          -  Willing and able to give informed consent

        Exclusion Criteria:

          -  Planned or performed diagnostic testicular biopsy (TESE) or percutaneous epididymal
             sperm aspiration (PESA)

          -  Use of donor-, cryopreserved- or electro-ejaculated semen

          -  Ovulation induction (OI) without IUI

          -  IVF for an absolute tubal factor

          -  Embryo-transfers after cryopreservation

          -  Embryo-transfer after pre-implantation genetic diagnosis

          -  Known genetic abnormalities related to infertility

          -  Known urological abnormality such as a varicocele or bilateral cryptorchism

          -  Use of other vitamin supplements
Male
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): An 8-year-old boy is brought to the clinic by his parents because of weakness and difficulty of standing up from a sitting position. The mother is healthy but had a brother who died in his 20th after being disabled and using wheelchairs in the last few years of his life. Physical examination shows 3/5 lower extremity muscle strength and enlarged calf muscles. The other physical examination and vital signs are unremarkable. Muscle biopsy showed absence of dystrophin protein. The patient is diagnosed with DMD.

Patient's own account: I brought my  8-year-old son to the doctor's clinic. He was struggling to stand up from a chair for the past few days. My wife is healthy but she was pretty worried since his brother died in his 20s after being disabled and using a wheelchair for the last years of his life. The doctor did an exam which highlighted weakness in the leg muscles and unusually large calf muscles. The rest of the exam was fine, and his vitals were normal. My son did a muscle biopsy, and it showed that the protein important for muscle strength and function is missing. The doctor diagnosed him with Duchenne muscular dystrophy.

Clinical trial: This is a Study to Get More Information About Non Ambulatory Boys & Men With Duchenne Muscular Dystrophy

Eligibility criteria:
Inclusion Criteria:

          1. For Non-ambulatory study, boys must be unable to walk without assistive devices for
             greater than or equal to one year.

          2. Age at onset of study for non-ambulatory boys and men: greater than or equal to 7
             years through age 22 years.

          3. Genetic or biopsy confirmation of dystrophinopathy or clinical diagnosis of DMD with
             biopsy/genetic confirmation in a primary relative.

        Exclusion Criteria:

        1. For Non-ambulatory study, the inability to understand and cooperate with the testing
        would exclude a subject. -
Male
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.
Subject must be at most 22 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Demographics and Findings of Upper Endoscopy Patients

Eligibility criteria:
Inclusion Criteria:

          -  Patients who present to the KCVA GI endoscopy unit with symptoms of reflux,upper
             abdominal pain, anemia (patients referred by their primary care physicians with a
             diagnosis of low hemoglobin (< 10 G/DL, and or dyspepsia

        Exclusion Criteria:

          -  Weight loss (Weight loss of > 10% of their mean body weight over last 6 months)

          -  Dysphagia

          -  Gastrointestinal bleeding

          -  Gastrointestinal malignancy

          -  Recent EGD (in the past 5 years)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: The Diagnosis and Mechanism of Pleural Effusion

Eligibility criteria:
Inclusion Criteria:

        Patients with pleural effusion, who has not been treated

        Exclusion Criteria:

        Patients with pleural effusion, who has already been treated
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: A Phase 2/ 3 Trial to Evaluate the Efficacy and Safety of BAY86-6150

Eligibility criteria:
Inclusion Criteria:

          -  Male subjects

          -  12 to 62 years-of-age

          -  History of moderate or severe congenital hemophilia A or B with inhibitors to FVIII or
             FIX

          -  4 or more bleeding episodes in the last 6 months before enrollment.

        Exclusion Criteria:

          -  Clinically relevant coagulation disorder other than congenital hemophilia A or B with
             inhibitors

          -  History of coronary and/or peripheral atherosclerotic disease

          -  Disseminated intravascular coagulopathy, or stage 2 hypertension

          -  Angina pectoris

          -  Myocardial infarction

          -  Transient ischemic attack

          -  Stroke

          -  Congestive heart failure

          -  Thromboembolic event
Male
No healthy subjects accepted to join the trial.
Subject must be at least 12 Years old.
Subject must be at most 62 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: Evaluating Different Modalities for Pleural Adhesiolysis at Assuit University Hospital

Eligibility criteria:
Inclusion Criteria:

          -  Patients with symptomatic pleural effusion in whom the symptoms excepted to be
             relieved by pleural fluid drainage.

          -  Presence of intrapleural adhesions as documented sonographically.

          -  Difficult thoracentesis.

          -  Failure of satisfactory pleural fluid drainage 24 hours following intercostal tube
             (ICT) placement provided that the tube was properly positioned and not obstructed.

          -  Written consent, free and informed.

        Exclusion Criteria: patients have contraindications for any of our procedures will be
        excluded.

          -  Contraindications for streptokinase instillation i.e. (Previous allergic reaction,
             bronchopleural fistula, trauma or surgery within 48 hrs, history of hemorrhagic
             stroke, coagulation defects and previous streptokinase thrombolysis).

          -  Patients who are unfit for general anaesthesia.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Somatropin Treatment to Final Height in Turner Syndrome

Eligibility criteria:
Inclusion Criteria:

          -  girl with Turner syndrome

          -  prepubertal, Tanner stage I breast

          -  height velocity less than 6 cm/year and height less than or equal to the tenth
             percentile for sex and age in general population

          -  at least 6 months (preferably 12 months) of accurate height measurements available for
             calculation of pre-study height velocity

          -  if thyroxine deficient, to have received replacement therapy, and for six months prior
             to enrollment have had normal thyroid function tests

        Exclusion Criteria:

          -  prior treatment with growth hormone

          -  presence of a Y component in karyotype with gonads in situ

          -  diabetes mellitus
Female
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.
Subject must be at most 13 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: A Trial Comparing Combination Therapy of Acetaminophen Plus Ibuprofen Versus Tylenol #3 for the Treatment of Pain After Outpatient Surgery

Eligibility criteria:
Inclusion Criteria:

        Patients may take part in this study if the answer is YES to all of these questions:

          -  Female or male between 17-65 years of age

          -  Going to have one of the following surgeries:

               -  umbilical hernia repair

               -  inguinal hernia repair

               -  small incisional or abdominal wall hernia repair

               -  laparoscopic cholecystectomy (gallbladder removed)

          -  Going home after their surgery the same day

          -  Have signed consent form.

        Exclusion Criteria:

        Patients have had or have:

          -  Been diagnosed with peptic ulcer disease or bleeding stomach ulcer in the recent past
             and are not currently on a proton pump inhibitor (special antacid medication, eg.
             Losec®, Pantoloc®, Prevacid®, Nexium®).

          -  Suffered from asthma

          -  Allergies to codeine, non-steroidal anti-inflammatory drugs (Advil®, Ibuprofen),
             aspirin, or acetaminophen

          -  Been taking other prescription pain medications prior to their surgery

          -  A history of chronic pain disorder

          -  Fibromyalgia (a chronic pain illness with symptoms of muscle aches, pain, stiffness,
             general fatigue and sleep problems)

          -  Active kidney disease or failure

          -  Known liver disease

          -  Are females who are pregnant or nursing

          -  A problem with alcohol or drug abuse.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 17 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Entailment