Patient case (clinical description): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient's own account: I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Clinical trial: A Research Study of How Oral Semaglutide Tablets Work in Healthy People Who Are Chinese

Eligibility criteria:
Inclusion Criteria:

          -  Chinese male or female, aged 18-55 years (both inclusive) at the time of signing
             informed consent.

          -  Body weight equal to or above 54.0 kg

          -  Body mass index (BMI) between 20.0 and 24.9 kg/m^2 (both inclusive)

          -  Considered to be generally healthy based on the medical history, physical examination,
             and the results of vital signs, ECG and clinical laboratory tests performed during the
             screening visit, as judged by the investigator.

        Exclusion Criteria:

          -  Female who is pregnant, breast-feeding or intends to become pregnant or is of
             child-bearing potential and not using highly effective contraceptive methods

          -  History of pancreatitis (acute or chronic) as declared by the subject.

          -  Family or personal history of multiple endocrine neoplasia type 2 (MEN2) or medullary
             thyroid carcinoma (MTC) as declared by the subject.

          -  History or presence of malignant neoplasms within the last 5 years (except basal and
             squamous cell skin cancer and in-situ carcinomas) as declared by the subject.

          -  History of major surgical procedures involving the stomach potentially affecting
             absorption of trial product (e.g., subtotal and total gastrectomy, sleeve gastrectomy,
             gastric bypass surgery) as declared by the subject.

          -  Smoker (defined as a subject who is smoking equal to or more than 1 cigarette or the
             equivalent per day).

          -  Unable or unwilling to refrain from smoking and use of nicotine substitute products
             during the inpatient periods, as judged by the investigator.

          -  Any blood draw in excess of 25 mL in the past month, or donation of blood or plasma in
             excess of 400 mL within the 3 months preceding screening.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Entailment