Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient's own account: I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Clinical trial: D-OCT of Facial Telangiectasia Treated With IPL

Eligibility criteria:
Inclusion Criteria:

          -  legally competent,

          -  at least 18 years of age

          -  persons able to read and understand spoken and written information in Danish or
             English.

          -  One or more facial telangiectasia

        Exclusion Criteria:

          -  wounds or ulcers in area of facial telangiectasia
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Study to Assess the Safety and Patients' Satisfaction of Tears Again* in the Treatment of Dry Eye Symptoms

Eligibility criteria:
Inclusion Criteria:

          -  Suffer from at least two of the following ocular symptoms: burning, stinging,
             excessive tearing, dryness, grittiness, foreign body sensation ( including patients
             suffering from blepharitis).

          -  Use artificial tears or any other treatment for these symptoms three or more times a
             day.

        Exclusion Criteria:

          -  Known hypersensitivity to Phenoxyethanol.

          -  Pregnant and lactating women.

          -  Receive other ophthalmic medication (except for eyelid hygiene preparations).

          -  Graft-versus-host disease patients.

          -  Participated during the last month in another clinical trial.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 85 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the office complaining of pain in the calf and knee when she bends down. The pain limits her activity. Her medical history is significant for osteoarthritis, for which she uses nonsteroidal anti-inflammatory drugs (NSAIDs) for the past two years. She is living with her husband and has 3 children. She doesn't smoke but drinks alcohol occasionally. Her vital signs are normal. On physical examination, there is a small effusion in the right knee. The effusion grew a little larger and she developed a tender swelling in the popliteal fossa and calf. Both the pain and swelling worsened as she bent and straightened her knee.

Patient's own account: I'm a 47-year-old woman, married with 3 kids. I don't smoke and I drink occasionally. I went to the doctor because of pain in my calf and knee when I was bending down. This has been limiting my daily activities. I have been diagnosed with osteoarthritis for which I have taken anti-inflammatory drugs for the past 2 years. The doctor saw a small fluid buildup in my right knee. This buildup became a bit bigger and I have a swollen calf. The pain is worse when I bend and straighten my knee.

Clinical trial: Autologous Conditioned Serum: Functional and Clinical Results

Eligibility criteria:
Inclusion Criteria:

          -  knee osteoarthritis >3 months in clinical and radiographic signs

          -  VAS for pain >50mm

        Exclusion Criteria:

          -  Hepatitis B

          -  Hepatitis C

          -  HIV

          -  pregnancy

          -  drug abuse

          -  other intra-articular injections <6 months

          -  surgery on affected knee <12 months
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 35 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: EFFEKT - Efficacy and Safety of Long-term Treatment With KOGENATE Bayer/FS

Eligibility criteria:
Inclusion Criteria:

          -  Patients with diagnosis of haemophilia A, treated with KOGENATE Bayer/FS as their only
             source of FVIII, decision taken by the investigator to administer KOGENATE Bayer/FS.
             For pretreated patients with more than 100 exposure days an inhibitor assessment
             within three months prior to enrollment should be available; for pretreated patients
             with less than 100 exposure days an inhibitor assessment at baseline should be
             available.

        Exclusion Criteria:

          -  Exclusion criteria must be read in conjunction with the local product information.
Male
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Famotidine in Subjects With Non-erosive Gastroesophageal Reflux Disease

Eligibility criteria:
Inclusion Criteria:

          -  Patients have heartburn with non-erosive gastroesophageal reflux disease.

        Exclusion Criteria:

          -  Patients have diseases which interfere with evaluation of the efficacy and safety in
             this study.

          -  Patients are receiving and/or have received prior to the enrollment the treatment
             which interfere with evaluation of the efficacy and safety in this study.

          -  Patients have severe cardiovascular, hepatic, renal and hematological disorders.

          -  Patients are allergic to or have a history of drug allergy to H2RA.

          -  Patients have or have a history of malignant tumors.

          -  Patients are pregnant or a lactating mother.

          -  Patients have participated in other clinical studies less than 12 weeks prior to
             submitting the informed consent.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Poor Ovarian Stimulation Response in In Vitro Fertilization (IVF) Program

Eligibility criteria:
Inclusion Criteria:

          -  Women at or under the age of 35 years.

          -  Normal thyroid stimulating hormone and prolactin levels.

          -  Normal ovulatory cycles (25-35 interval days), together with proven patent fallopian
             tubes at hysterosalpingography or laparoscopy done within six cycles preceding the
             ICSI cycle.

          -  Presence of both ovaries with normal findings as assessed by trans-vaginal ultrasound
             and laparoscopy.

          -  All male partners had a normal semen analysis according to WHO criteria (WHO, 2010),
             done within 6 months preceding the ICSI cycle

        Exclusion Criteria

          -  Chronic medical disorders such as diabetes.

          -  Previous inadequate response to ovulation induction.

          -  Polycystic ovary syndrome.

          -  Women who performed ovarian surgery and cases of endometriosis diagnosed by
             laparoscopy or suspected by ultrasound or CA-125 assay.

          -  Abnormal pelvic pathology or congenital anomalies.
Female
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 35 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: The Accuracy of Swallowing Disturbance Questionnaire in Screening Inpatient Elderly

Eligibility criteria:
Inclusion Criteria:

          -  (1) age over 65 years old; (2) does not use enteral tube feeding; (3) no serious
             mental or cognitive conditions; no aphasia

        Exclusion Criteria:

          -  (1) age under 65; (2) use enteral tube feeding; (3) subjects with serious mental or
             cognitive conditions or aphasia (4) Allergy to barium sulfate suspension
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Expressive Writing in Male Infertility

Eligibility criteria:
Inclusion Criteria:

          -  Male infertile patients with a pathological spermiogram according to WHO criteria

        Exclusion Criteria:

          -  Drugs affecting sperm quality

          -  Patients with chromosomal anomalies affecting sperm quality (e.g. Klinefelter-
             Syndrome)

          -  Severe Psychiatric disorder defined as psychotic disorder (schizophrenia, bipolar
             disorder) or substance-related disorder

          -  Patients currently in psychotherapeutic or psychiatric therapy
Male
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 55 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 30-year-old man who is a computer scientist came to the clinic with the lab result stating azoospermia.  The patient is sexually active with his wife and does not use any contraception methods.  They have been trying to conceive for the past year with no success.  The patient has a past medical history of recurrent pneumonia, shortness of breath, and  persistent cough that produces large amounts of thick sputum. The patient had multiple lung infections during childhood. He does not smoke, use illicit drugs or alcohol.  The patient has no history of other medical conditions including allergies or any kind of surgery.  On physical examination, the digits show clubbing.  An ultrasound shows bilateral absence of the vas deferens, and FEV1 was 75% on the respiratory function test.

Patient's own account: I'm a 30-year-old computer scientist. I did some lab tests that came back quite alarming, stating that I have azoospermia?! I'm sexually active with my wife and we don't use contraception. We've been trying to have a child for the past year. I have a medical history of pneumonia and shortness of breath and regular wet cough. I had several lung infections when I was a kid. That's why I'm very careful and don't smoke, do drugs, or drink. I don't have other medical conditions including allergies or any kind of surgery. The doctor did the clubbing test on my fingers, which was positive. I also did an ultrasound and it showed that I'm missing the tubes that carry sperm around. I also had a 75% for my respiratory function test.

Clinical trial: Impact of Air Pollution on Chronic Respiratory Diseases

Eligibility criteria:
Inclusion Criteria:

          -  Normal: People with no lung lesions in chest X-ray and St. George's Respiratory
             Questionnaire score <25, and post bronchodilator FEV1/FVC (forced expiratory volume at
             one second/forced vital capacity) >= 0.7 and FEV1 >= 80% and FVC >= 80%.

          -  Chronic obstructive pulmonary disease: Patients with over 10 pack-years of smoking
             history and post bronchodilator FEV1/FVC <0.7 and FEV1 < 80%, and no other reason for
             decline of lung function.

          -  Asthma: Patients with FEV1/FVC < 0.85 and increase in over 12% and 200mL of FEV1 by
             bronchodilator inhalation. Patients with P20 < 16mg/dL by bronchial provocation test.

          -  Idiopathic pulmonary fibrosis: Shows usual interstitial pneumonia according to chest
             CT and has no other reasons such as systematic diseases or medication history.

        Exclusion Criteria:

          -  Subjects who refused for enrollment in the study

          -  Subjects who experienced an acute exacerbation within 1 month.

          -  Subjects under age of 19.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 19 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation

Eligibility criteria:
Inclusion Criteria:

          -  Chronological age (CA) between 3 and 10 for girls

          -  Chronological age between 3 and 12 for boys

          -  Height for CA below - 2 SD

          -  Birth length for CA below -2SD

        Exclusion Criteria:

          -  Endocrine disease except well-substituted hypothyroidism

          -  Sever chronic disease

          -  Skeletal dysplasia

          -  Known chromosomal aberration

          -  Ongoing treatment with steroids

          -  Known intrauterine infection
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.
Subject must be at most 12 Years

Eligibility (NLI label): Contradiction