Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: Low and High Dose Dextrose Prolotherapy in the Treatment of Lateral Epicondylitis

Eligibility criteria:
Inclusion Criteria:

          -  Those who admit Kirsehir Ahi Evran University Hospital and is diagnosed with lateral
             epicondylitis,

          -  Participants with unilateral or bilateral lateral epicondylitis and pain and
             functional limitations due to this condition,

          -  who can read and write in Turkish,

          -  participant's admission participating in the study,

          -  participants who do not have exclusion criteria,

        Exclusion Criteria:

          -  receiving any injection therapy to the elbow area in the last 3 months,

          -  participants with complaints less than 3 months(acute lateral epicondylitis)

          -  previously surgery on the elbow area,

          -  having a history of acute trauma or fracture in the elbow area,

          -  have local dermatological problems,

          -  have a local infection in the treatment area,

          -  those who are allergic to dextrose,

          -  with coagulation disorders or using anticoagulant drugs,

          -  with an autoimmune disease,

          -  with type 1 or type 2 diabetes mellitus,

          -  have unregulated hypertension,

          -  have immune dysfunction,

          -  with malignancy or diagnosed with a malignancy in the last 5 years,

          -  pregnancy or lactation,

          -  having cervical radiculopathy in the same extremity,

          -  with cognitive dysfunction,

          -  patients with paralysis in the same extremity,

          -  lack of cooperation due to cognitive impairment,

          -  participant's refusal to participate in the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Contradiction