Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 41-year-old woman comes to the dermatology clinic complaining of facial redness, especially on her forehead and cheeks. She noticed that the redness gets worse in the summer and after sun exposure. She is otherwise healthy. On physical examination, she has multiple papules and pustules present on her forehead, cheeks, and nose on a background of erythema and telangiectasias. There are no other lesions or nodules. The patient is married and has 2 children who are 5 and 9 years old. She has IUD and doesn't wish to have more kids. She does not smoke or drink alcohol. Her vital signs are normal, and BMI is 21.

Patient's own account: I'm 41, married with 2 lovely kids who are 5 and 9 years old. I have an IUD and I don't want to have more kids. I don't smoke or drink alcohol. I had to go to the dermatology clinic because I had terrible redness on my face, especially on my forehead and cheeks. It got worse in the summer and after being under the sun. I'm usually healthy. They conducted a physical exam and they found several lesions and pustules on my forehead, cheeks and nose and they also found some signs of erythema and telangiectasia. My vitals were normal, and my BMI is 21.

Clinical trial: Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients

Eligibility criteria:
Inclusion Criteria:

          -  Between the ages of 18-70

          -  No systemic illness

          -  No other inflammatory dermatoses except for rosacea

          -  No smoking

          -  Not using any topical, systemic treatment and sunblock at least a month for rosacea or
             other condition

        Exclusion Criteria:

          -  Systemic illness

          -  Other inflammatory dermatoses except for rosacea

          -  Smoking

          -  Using any topical, systemic treatment and sunblock for rosacea or other condition

          -  Type 4 rosacea patient (only ocular involvement)
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU)

Eligibility criteria:
Inclusion Criteria:

          -  BMI < 35

          -  Premenopausal

          -  Uterine size <20 gw

          -  Willingness to participate to the research

          -  Uterine fibroids with typical symptoms

          -  Maximum of 4 treated fibroids

          -  Dominant fibroid >2.5cm

          -  >50% of the fibroid is treatable

        Exclusion criteria

          -  Unspecified pelvic tumours or ovarian masses, PID

          -  Major corrective surgery to uterus (simple myomectomy excluded)

          -  Major uterine anomalies

          -  Unability to calculate the volume of uterine fibroids

          -  Marked uterine calcification

          -  Marked scarring of the lower abdomen

          -  Suspicion of malignancy

          -  Marked general health problem contraindicating MRI

          -  Claustrophobia
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 50 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Physiology, Imaging and Modeling of Essential Tremor

Eligibility criteria:
Inclusion Criteria:

          -  Existing unilateral or bilateral VIN DBS for ET, non-demented (MMSE>24), and must have
             a documented suboptimal tremor suppression on two successive visits (compared to the
             baseline post-operative improvement at 6 months following ET DBS surgery). For
             bilateral cases, the most affected tremor side will be studied.

        Exclusion Criteria:

          -  No diagnosis of Essential Tremor
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 67-year-old woman comes to the clinic due to recent episode of choking, dysphagia, and cough.  Her other medical problems include hypertension, dyslipidemia, and osteoarthritis.  She does not smoke or use alcohol. She lives with her husband and she is able to do her own daily activities. She used to teach elementary school. Blood pressure is 135/80 mm Hg.  The patient's breath smells bad. Other physical examinations are normal.  A barium swallow study reveals an abnormality in the upper esophagus with an outpouching at the junction of the lower part of the throat and the upper portion of the esophagus.

Patient's own account: I'm a 67-year-old lady, and I went to the clinic due to nonstop choking, difficulty swallowing, and coughing. I also suffer from hypertension, cholesterol, and osteoarthritis. I do not smoke or drink alcohol. I live with my husband, and we are independent retired elementary school teachers. During the exam, my blood pressure was 135/80 mm Hg. The doctor told me I had a smelly breath. How embarrassing! The rest of my physical exam was normal. I did a barium swallow test, which is an X-ray of my throat, which revealed a problem in the upper part of my esophagus, where there's a small pouch or bulge at the spot where my throat meets the esophagus.

Clinical trial: Translation of the Sydney Swallow Questionnaire and Validation of the German Version

Eligibility criteria:
Inclusion criteria: - patients with diagnosed dysphagia "of any causes"

          -  sufficient proficiency in german

          -  voluntary participation

        Exclusion criteria: - insufficient knowledge of the german language

          -  cognitive limitations

          -  reduced general state of health
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD)

Eligibility criteria:
Inclusion Criteria:

          -  diagnosis of typical GERD

          -  partial responder to a stable standard clinical symptoms control dose of PPI therapy

          -  body mass index ≤ 32 kg/m2

        Exclusion Criteria:

          -  exclusively atypical symptoms of GERD

          -  symptoms that have been shown not to be associated with GERD

          -  erosive oesophagitis

          -  treated with a dose of PPI greater than the dose indicated for clinical symptom
             control of GERD

          -  hiatus hernia > 3 cm

          -  current diagnosis of co-existing psychiatric disease

          -  known clinical significant allergy or known hypersensitivity to drugs

          -  is pregnant or breast-feeding

          -  has received sodium valproate or topiramate within 30 days of Screening

          -  has a history of a significant medical condition that may affect the safety of the
             patient or preclude adequate participation in the study
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Effect of Bright Light on Sex Hormones and Ovulation in Humans

Eligibility criteria:
Inclusion Criteria:

          -  Age 19-40 years

          -  Mean menstrual cycle 28-38 days

          -  Good general health

          -  Generally normal sleep-wake regimen

          -  Motivated for free participation

        Exclusion Criteria:

          -  Low cooperation

          -  Medications known to interfere with hormone release

          -  Clinically evident endocrine abnormalities including the signs of

          -  Hyperandrogenism

          -  Travel over several time zones during two months prior the study
Female
Accepts Healthy Volunteers
Subject must be at least 19 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: High Intensity Strength Training & Bone Mineral Density in Young Women

Eligibility criteria:
Inclusion Criteria:

          -  Participants include young and healthy women between the ages of 18-30, who have not
             engaged in strength training for the last 6 months.

        Exclusion Criteria:

          -  Subjects will be excluded from the study if they have any condition that preclude them
             from taking part in the exercise testing procedures or the 24 week exercise program or
             if they fail to obtain the required amount of training sessions.
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 30 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient's own account: I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Clinical trial: Management of Persistent Epistaxis Using Floseal Hemostatic Matrix

Eligibility criteria:
Inclusion Criteria:

          -  All patients age 18+ presenting with epistaxis that requires an ENT consult that had a
             first attempt at treatment by an emergency physician.

        Exclusion Criteria:

          -  Patients will be excluded based on the presence of a hypo-coagulable state. Including
             patients actively taking anti-coagulant medications or other patients with either
             acquired or hereditary bleeding disorders.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: Yoga as an Intervention for Women With Knee Osteoarthritis

Eligibility criteria:
Inclusion Criteria:

          -  Female - 50 years of age or older

          -  Knee pain on most days of the week

          -  Less than 30 minutes of morning stiffness

          -  Bony enlargement

          -  Bony tenderness to palpation

          -  Signs of inflammation

          -  Able to safely climb 2 flights of stairs without aid

          -  Visited a family physician within the last 12 months

        Exclusion Criteria:

          -  Any other forms of arthritis

          -  Osteoporosis

          -  History of patellofemoral symptoms

          -  Active non-arthritic knee disease

          -  Knee surgery

          -  Use of cane or walking aid

          -  Unstable heart condition

          -  Neurological conditions

          -  Skin allergy to medical tape

          -  Hip or ankle injuries in past 3 months

          -  Any injuries that would prohibit participation in yoga

          -  Ipsilateral hip or ankle conditions

          -  Currently receiving cancer treatment

          -  Currently pregnant
Female
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Determinants of SARS-COV2 (COVID-19) Persistence After Convalescence

Eligibility criteria:
Inclusion Criteria:

          -  Laboratory confirmed SARS-CoV-2 using currently available laboratory testing
             techniques (e.g.,RT-PCR, Immunoglobulin M (IgM) /IgG) or clinical history compatible
             with a COVID-19 like illness(fever, cough, shortness of breath).

          -  Negative participants with no known prior COVID-19 diagnosis or COVID vaccine

          -  At least 7 years of age

          -  Participants are eligible to provide semen and breast milk samples if they are 18
             years of age or older

        Exclusion Criteria:

          -  Age <7

          -  Intercurrent conditions that in the opinion of the investigator would confound the
             findings of the study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 7 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Hemophilia Inhibitor Previously Untreated Patient Study

Eligibility criteria:
Inclusion Criteria:

          -  Severe hemophilia A with FVIII activity < 1% normal

          -  Weight > 3.5 kg at the time of baseline study evaluation

          -  Informed consent, approved by appropriate Institutional Review Board/Independent
             Ethics Committee, has been administered, signed, and dated

        Exclusion Criteria:

          -  Prior exposure to clotting factor concentrates or blood products

          -  Other chronic disease

          -  Currently participating in another investigational drug study.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction