Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death

Eligibility criteria:
Inclusion Criteria:

          -  Adult patients (>18 years)

          -  Confirmed COVID-19 infection by real-time PCR from a respiratory or other body sample
             within 48 hours of testing.

          -  Mild to moderate infection or asymptomatic patients with comorbidities: Symptomatic
             patients with fever >37.9ºC or cough or dyspnea or chest pain, not fulfilling severity
             exclusion criteria. We will include patients regardless of time since symptom onset.
             In addition, we will include asymptomatic patients with comorbidities including
             cardiac, pulmonary, diabetes, chronic renal failure or liver disease hospitalized for
             observation.

          -  Informed consent from patient or legal representative.

        Exclusion Criteria:

          -  Severe infection, defined as need for invasive or non-invasive ventilator support,
             ECMO or shock requiring vasopressor support.

          -  Unable to take oral medication

          -  Known allergy to HCQ or chloroquine

          -  Prolonged QT, defined as QTc ≥450 milliseconds for men and as QTc ≥470 for women

          -  Severely reduced LV function (Ejection fraction<30%)

          -  Retinopathy

          -  Pregnancy or breast feeding

          -  Concomitant treatment with azithromycin, flecainide, amiodarone, digoxin,
             procainamide, propafenone, thioridazine, pimozide.

          -  Chronic chloroquine/ HCQ treatment (within 1 month)

          -  Need for hemodialysis

          -  Participating in another RCT for treatment of COVID-19
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Treatment Of Children With Short Stature At An Age Of 3-7 Years Who Were Born Small For Gestational Age

Eligibility criteria:
Inclusion Criteria:

          -  Birth length below -2 SD

          -  Height at start below - 2 Sd

        Exclusion Criteria:

          -  Any endocrine or chronic disease

          -  Any known syndrome with short stature
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 3 Years old.
Subject must be at most 7 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: A Study to Evaluate 4DCT Controls

Eligibility criteria:
Inclusion Criterion:

          -  Age ≥ 18 and ≤ 60 years.

          -  Control subjects without any history of wrist injury or disease.

        Exclusion Criteria (applied to both wrists for control subjects):

          -  Previously-diagnosed rheumatological conditions or connective tissue diseases;

          -  Inability to be appropriately positioned in the scanner for the imaging;

          -  Congenital malformations of the wrist or forearm;

          -  Diagnosed wrist osteoarthritis

          -  Age under 18 or over 60.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 60 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: Management of Bone Defects Around the Elbow

Eligibility criteria:
Inclusion Criteria:

          -  HMRS of the elbow, distal humerus or total humerus

        Exclusion Criteria:

          -  Unwillingness to participate
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: Application and Comparison of Fuzzy Scale for the Evaluation of Pain Skeletal Muscle With the Numerical Pain Scale

Eligibility criteria:
Inclusion Criteria:

          -  Included in this study were male and female subjects

          -  Age between 18 and 90 years

          -  With complaint of skeletal muscle pain

          -  Do not present cognitive deficit that makes the study impossible

        Exclusion Criteria:

          -  Individuals who did not agree to participate in the study

          -  Volunteers with decreased range of motion

          -  Volunteers without complaint of skeletal muscle pain
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Oocyte Retrieval Progesterone Levels and IVF

Eligibility criteria:
Inclusion Criteria:

          -  18 to 40 years of age

          -  BMI of 18 to 30 kg/m2

          -  regular menstrual cycles from 25 to 32 days

          -  established diagnosis of infertility.

        Exclusion Criteria:

          -  Less then 18 or more then 40 years old

          -  BMI less then 18 or more then 30 kg/m2

          -  irregular menstrual cycles
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Relation of Implantation Site to Placental Site

Eligibility criteria:
Inclusion Criteria:

          -  Single intrauterine pregnancy

          -  Gestational age less than 10 weeks

        Exclusion Criteria:

          -  Any condition distorting uterine cavity as myoma, uterine anomalies.

          -  Absent fetal pulsations

          -  Any condition needing termination of early pregnancy as molar pregnancy or severe
             deteriorating maternal disease
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Mapping the Target for the MRgFUS Treatment of Tremor

Eligibility criteria:
Inclusion Criteria:

          -  Male or female

          -  18 years of age or older

          -  Any ethnic background

          -  History of a primary diagnosis of essential tremor or Parkinson's disease

          -  Present for the MRgFUS tremor treatment

          -  Ability to understand and agree to informed consent as determined by referring
             physician

        Exclusion Criteria:

          -  Inability to give informed consent

          -  Contraindications for MRI, including

               1. Intracranial clips

               2. Metal implants

               3. External metallic devices/objects/clips within 10 mm of the head

               4. Suspected or confirmed metal in eyes (history of welding or similar activity)

               5. Cardiac pacemaker

               6. Pregnant or potentially pregnant - pregnancy tests will be offered to women of
                  childbearing age at no cost to the patient. (A SOC pregnancy test (Urine test)
                  will be done for women of child bearing age if requested/required at the time of
                  check-in at Tisch.This will be billed to the research study). The result of the
                  test (if performed) will be added to the patient's chart in EPIC.

               7. No vulnerable populations will be enrolled.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Efficacy of Gaviscon-Advance® in Suppressing Post-supper Acid-pocket and Night-time Acid-reflux in Obese Participants

Eligibility criteria:
Inclusion Criteria:

          1. Aged greater than or equal to 18 years and less than or equal to 70 years.

          2. BMI >27.5 (based on kg/m2)

        4. Not taking acid suppressant PPI and H2 receptor blockers 5. Not taking antacids or
        alginate preparations, except those administered as part of study procedure.

        Exclusion Criteria:

          1. Those with gastrointestinal symptoms indicative of GERD, gastric carcinoma, previous
             or current peptic ulcer disease.

          2. Those with a history of upper GI surgery prior to this.

          3. Those with haematological disorders, bleeding tendency, recurrent nose bleeds or
             treatment with anti-coagulants).

          4. Those who had any previous history of allergy or known intolerance to any of the study
             drugs or the following formulation constituents: Gaviscon® liquid: sodium alginate,
             sodium bicarbonate and calcium carbonate

          5. Those with physical, neurological or psychiatric conditions preventing repeated visits
             to hospital or compliance with study procedures.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Dietary Advice on Prescription in Kungsbacka

Eligibility criteria:
Inclusion Criteria:

          -  BMI 28-35

        Exclusion Criteria:

          -  Severe disease
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Health Practice of Hemophilia Patiente Care During Pregnancy, Delivery and Newborn Children

Eligibility criteria:
Inclusion Criteria:

          -  Adult

          -  Hemophilia A or B

          -  Pregnancy between 2014 and 2016

        Exclusion Criteria:

        - Opposition
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction