Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: BOUNCE to Health: A Healthy Lifestyle Program

Eligibility criteria:
Inclusion Criteria:

          -  Both parental guardians (mother and father) and target child must be of Hispanic or
             African American descent

          -  Child must be between the ages of 9-14 years

          -  Child must be overweight/obese as defined by a body mass index percentile for age-
             gender specific between the 85th-100th percentile

          -  Child must have no physical disability or medical conditions that interfere with their
             participation in an exercise program

          -  Children must have no extensive diet restrictions that would hinder their
             participation in the BOUNCE nutrition component (e.g., unable to eat solid foods)

          -  All children will be required to submit evidence of a medical examination conducted by
             a health professional

          -  Parental guardians and child must be available to participate for the duration of the
             BOUNCE summer

        Exclusion Criteria:

          -  Child and parental guardians are not Hispanic or African American

          -  Child is not between the ages of 9-14 years

          -  Child is underweight or normal weight (BMI < 85 percentile) or are morbidly obese (BMI
             > 100 percentile)

          -  Child or mother are pregnant or physically unable to participate

          -  Child has extensive diet restrictions that would hinder their participation in the
             BOUNCE nutrition component (e.g., unable to eat solid foods)

          -  Child does not have submitted evidence of a medical examination conducted by a health
             professional

        Note: We will encourage both maternal and paternal guardians to participate in the
        measurements and interventions. However, if the paternal guardian refuses to participate or
        there is no father figure present in the family, maternal guardian-child pairs will be
        still eligible to participate in this study. If the children are of mixed race, but
        identify themselves as Hispanic or African American and at least one of their parents is
        either Hispanic or African American, they will be still eligible to participate.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 9 Years old.
Subject must be at most 14 Years

Eligibility (NLI label): Contradiction