Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): The patient is a 38-year-old man with cough and body ache that started 3 days ago.  He had fever and chills at the beginning and has low grade fever at the time of visit. He feels tired and sleepy. His body ache and myalgia get better after using Tylenol. The PCR test for Covid is positive. His vital signs are within normal limits with a body temperature of 37.9 C. There is no lymphadenopathy or white exudates in the pharynx.

Patient's own account: I was feeling really sick the other day, to the point that I showed up at the doctor's office. I was coughing, and my body was hurting for 3 days. I had a fever and chills and felt tired and sleepy. I got better after using Tylenol. They did a PCR Covid test on me, and it was positive! My vitals were normal, and my temperature was 37.9 C. I had no swelling around my neck or white spots on the back of my throat.

Clinical trial: The Nitazoxanide Plus Atazanavir for COVID-19 Study

Eligibility criteria:
Inclusion Criteria:

          -  Willingness and ability to provide written informed consent

          -  At least 18 and not more than 75 years of age at study entry

          -  SARS-CoV-2 infection confirmed by PCR test within 4 days before randomization

          -  Currently symptomatic (fever or chills, cough, myalgia, sore throat, shortness of
             breath, or new onset of anosmia or ageusia) and at COVID-19 isolation and treatment
             centre

        Exclusion Criteria:

          -  Inability to take orally administered medication or food

          -  Known hypersensitivity to study medication

          -  Pregnant or lactating (unless practicing exclusive replacement feeding for the entire
             study duration)

          -  Participation in any other interventional trial for COVID-19 (observational study
             co-enrollment allowed)

          -  Concurrent treatment with other agents with actual or possible direct-acting antiviral
             activity against SARS-CoV-2 less than 24 hours prior to study drug dosing

          -  Concurrent use of agents with known or uncertain interaction with study drugs,
             including ritonavir

          -  Requiring mechanical ventilation at screening

          -  Alanine Aminotransferase (ALT) or aspartate aminotransferase (AST) above 5 times upper
             limit of normal (ULN)

          -  Creatinine clearance below 50 mL/min using the Cockcroft-Gault formula for
             participants above 18 years of age
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Liquid Biopsies for the Personalized Management of Patients With Hereditary Diffuse Gastric Cancer

Eligibility criteria:
Inclusion Criteria:

        Case:

          -  Patient>18 years old

          -  CDH1 or CTNNA1 germline pathogenic variant.

          -  No history of diffuse gastric cancer.

          -  French social security.

          -  Ability to understand and willingness to sign a written informed consent document.

        Volunteers:

          -  Patients > 18years old

          -  Patients with no oncological history

        Exclusion Criteria: for both arms

          -  Patients with cancer being treated

          -  Patients with metastatic cancer

          -  Medical contraindication to general anesthesia or FOGD (bleeding disorder, pregnant
             women )

          -  Patients under guardianship or curator
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 32-year-old woman comes to the hospital with vaginal spotting.  Her last menstrual period was 10 weeks ago. She has regular menses lasting for 6 days and repeating every 29 days. Medical history is significant for appendectomy and several complicated UTIs. She has multiple male partners, and she is inconsistent with using barrier contraceptives. Vital signs are normal.  Serum β-hCG level is 1800 mIU/mL, and a repeat level after 2 days shows an abnormal rise to 2100 mIU/mL.  Pelvic ultrasound reveals a thin endometrium with no gestational sac in the uterus.

Patient's own account: I just turned 32 and last morning I woke up with strange blood stains on my underwear. My last periods were more than 2 months ago, which is unusual for me because I used to have regular periods lasting for 6 days every 29 days, more or less. I had several UTIs in the past. I also had appendicitis. I'm currently seeing several men and, to be honest, some of them do struggle to wear a condom. I went to the hospital to check myself up and they told me that my vitals were normal. I also had a blood test on Monday, and my β-hCG level was 1800 mIU/mL, and then on Wednesday, it went up to 2100 mIU/mL. The gynecologist also did an ultrasound and she told me that, hopefully, there was no ovule.

Clinical trial: Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol

Eligibility criteria:
Inclusion Criteria:

          1. Patients with a history of one or more failed IVF cycles with three or less retrieved
             oocytes

          2. No age limitation

          3. Patients with an inadequate ovarian response in previous cycle

          4. Low estradiol (E2) levels in response to ovarian stimulation in previous cycle

          5. Lower number of retrieved oocytes in previous trials.

        Exclusion Criteria:

          1. Severe male factor (azospermia)

          2. Hydrosalpinx

          3. History of endometriosis

          4. Endocrine or metabolic disorders

          5. Follicle stimulating hormone (FSH) level > 15 mIU.

          6. Antimullerian hormone (AMH)< 0.5 ng/ml

          7. Any uterine causes of infertility e.g. septate uterus
Female
No healthy subjects accepted to join the trial.
Subject must be at least 20 Years old.
Subject must be at most 39 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Long Term Incidence and Effect of de Novo GERD After Laparoscopic Sleeve Gastrectomy in Chinese Population

Eligibility criteria:
Inclusion Criteria:

          -  Chinese patients who received laparoscopic sleeve gastrectomy at Prince of Wales
             Hospital, The Chinese University of Hong Kong

          -  SG has been performed more than 36 months

          -  Patient received preoperative OGD and GI symptom assessment with C-GIQLI questionnaire

          -  Willing and able to consent to the study

        Exclusion Criteria:

          -  Revisional surgery

          -  Concomitant surgeries (except hiatal repair/ cholecystectomy)

          -  Mentally incompetent patients or patients less than 18 years old

          -  Pregnant patients

          -  Inmates

          -  Unable/unwilling to consent to the study

          -  Unable/unwilling to undergo follow-up assessments
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Observational Study on the Use of NovoSeven® for Haemostatic Treatment of Bleeding Episodes in Patients With Acquired Haemophilia

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosed with acquired haemophilia

          -  Treated with activated recombinant human factor VII as first line treatment

          -  Treated with activated recombinant human factor VII after January 2011

        Exclusion Criteria:

          -  Patients with first diagnosis before january 2010 and having a relapse after january
             2011

          -  Known hypersensitivity to NovoSeven®, or to mouse, hamster or bovine protein
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Resting Postural Tremor in Multiple Sclerosis

Eligibility criteria:
Inclusion Criteria:

        Group 1:

          -  Definite diagnosis of MS

          -  prevailed motor deficit of upper extremities, but without visible tremor

          -  stable clinical status in the preceding 3 months

          -  Expanded Disability Status Scale score (EDSS) ≥ 2 ≤ 7.5, and

          -  no corticosteroid therapy in the preceding month

        Group 2:

          -  Healthy volunteers in the age of 20-70 years will be employed

          -  There will be defined as persons without any neurological disease diagnose at the time
             of the measurement.

        Exclusion Criteria (both groups):

        Patients with factors disturbing mobility (e.g. stroke, pregnancy, fractures) were excluded
        from the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 70 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 27-year-old woman comes to the dermatology clinic with skin rash and oral ulcers.  The rashes are mildly itchy. The patient has no other medical conditions and takes no medications.  Vital signs are normal.  On examination, there are pink papules symmetrically distributed over the anterior surfaces of the shins and ankles. There are some white ulcerated papules on her buccal mucosa. She is in relationship with her boyfriend and has only one sexual partner. Her boyfriend uses condoms. She smokes 1 to 2 cigarettes a day and drinks a beer daily. Biopsy reveals prominent hyperkeratosis with a thickened granular layer.  There is an infiltration of mononuclear cells in the superficial dermis that involves the overlying epidermis. The rete ridges have a sawtooth appearance.

Patient's own account: I went to the dermatologist because I had rashes on my skin and ulcers in my mouth. The rashes were not that itchy. I don't get it! I'm 27, I don't take medication, nor I don't have any other illnesses. My vitals were normal. My doc told me there were pink spots on the back of my throat. I'm heterosexual and have been only with my boyfriend and he uses condoms. I smoke 1 or 2 cigarettes a day and I drink a beer to accompany it. I had a biopsy and it showed some thick and grainy skin texture. The doc said it's an immune reaction.

Clinical trial: Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial

Eligibility criteria:
Inclusion Criteria:

          -  Age 18 or above

          -  Ethnic Chinese male or female

          -  Smokes at least 2 cigarettes per day

          -  Have no intention to quit in the near future

          -  Intends to reduce smoking in the next 7 days

          -  Has no contraindication to NRT

        Exclusion Criteria:

          -  Subjects who are psychologically or physically unable to communicate

          -  Children and teenagers (age below 18)

          -  Pregnant or intention to become pregnant within the next 6 months

          -  Those on regular psychotropic medications and in the presence of any serious health
             problems that may make them unsuitable for using NRT, such as recent stroke,
             palpitation, or other life threatening conditions
No condition on gender to be admitted to the trial.

Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: The Effect of Kinesio Taping on Wrist Flexor Sensorimotor Control in Healthy People

Eligibility criteria:
Inclusion Criteria:

        1. Healthy people who are 20-40 years old

        Exclusion Criteria:

          1. Have irreversible injury on forearm, wrist or hand

          2. Feel pain or any uncomfortable symptom on forearm, wrist or hand

          3. Muscular disease on upper extremity in 6 months

          4. Impaired sensation

          5. Allergy

          6. Neurological disease
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 20 Years old.
Subject must be at most 40 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 51-year-old man comes to the office complaining of fatigue and some sexual problems including lack of libido. The patient doesn't smoke or use any illicit drug.  Blood pressure is 120/80 mm Hg and pulse is 70/min.  Oxygen saturation is 99% on room air.  BMI is 24 kg/m2.  Skin examination shows increased pigmentation. Genotype testing is consistent with homozygosity for the C282Y mutation. Laboratory study shows transferrin saturation of 55% and serum ferritin of 550 μg/L. He is diagnosed as a case of hemochromatosis.

Patient's own account: I am 51 years old and I just came back from the doctor's office. I'm sick and tired of being that exhausted, reaching the point where me and my lovely wife are not touching each other anymore! I'm not smoking or doing drugs! My blood pressure was 120/80 mm Hg, and pulse was 70/min and my oxygen saturation 99%. My BMI is 24. My skin also turned a bit darker lately. He tested my genes and told me that I have a mutation of the C282Y gene. I also did lab tests where my transferrin saturation was 55% and serum ferritin was 550  μg/L. The doctor diagnosed me with iron overload.

Clinical trial: Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study

Eligibility criteria:
Inclusion Criteria:

          -  Patients between 18 and 80 years

          -  C282 homozygosity

        Exclusion Criteria:

          -  corticosteroids during the last 3 months

          -  following treatments during the last 6 months : anabolic steroids, growth hormone,
             hormone therapy for menopause, tibolone, raloxifene.

          -  following treatments during inclusion or in the last 6 month : teriparatide,
             parathormone, fluor, strontium ranelate, biphosphonate.

          -  cancer or evolutionary hemopathy (including monoclonal gammopathy)

          -  pregnancy at inclusion time

          -  treated osteoporosis

          -  patient in wich follow up seems hard

          -  inclusion in another study incompatible with this one
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: A Study to Test the Impact of an Improved Chulha on Respiratory Health of Women and Children in Indian Slums

Eligibility criteria:
Inclusion Criteria:

          -  Woman ≥18 years who cooked more than 50% of the meals during the past 30 days (primary
             cook) and one child per household (0-5 years) will be included

          -  Both households with and without children will be included

          -  Women/mothers who are capable of being interviewed

          -  Will not migrate in the upcoming 2 months as far as the participants can predict

          -  Households cooking solely with traditional stove (chulha) or a combination of a
             traditional stove and a kerosene/diesel stove will be included

        Exclusion Criteria:

          -  Households with a cooking area outside the house will be excluded

          -  Persons who are seriously ill will be excluded from the study
Female
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old woman comes to the emergency department with a history of nosebleeds lasting for 1 hour. She has a history of heavy menses as well as occasional gum bleeding following dental procedures. Her mother also has a history of menorrhagia. Laboratory tests reveal increased bleeding time and slightly increased partial thromboplastin time. She has no other medical conditions and is otherwise healthy. Her coagulation study shows CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL. She is not smoking or using any kind of illicit drugs. She uses alcohol occasionally and is in ra elationship with her boyfriend for the past 2 years.

Patient's own account: I had to rush to the ER because of a non-stop nosebleed that had been on for 1 hour. As a 23-year-old, I always had heavy periods, and sometimes, my gums would bleed after going to the dentist or brushing my teeth. I thought that it was not very alarming since my mom also had heavy periods. I did some lab tests that showed that I had increased bleeding time and long clotting time. Otherwise, I'm pretty healthy, and I don't smoke or take any kind of drugs. I drink only at parties from time to time. I have been with my boyfriend for the last 2 years. I did a coagulation study and I got the following results: CB = 0.30 IU/mL and FVIII:C = 0.37 IU/mL.

Clinical trial: Music in the Emergency Department (ED): Phase II

Eligibility criteria:
Inclusion Criteria:

          -  Language: english

          -  Cognitive skill/education: grade 2 reading level or above

        Exclusion Criteria:

          -  Language: Non-english speaking

          -  Age: Less than 18

          -  Cognitive skill/education: lower than grade 2 reading level
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment