Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Use of MRI for Assessing Stomach Relaxation in Response to a Meal

Eligibility criteria:
Inclusion criteria for Dyspeptic patients (30 required)

          -  One or more of eight postprandial dyspeptic symptoms i.e. fullness, bloating,
             epigastric discomfort, early satiety, nausea, vomiting, belching, pain for a minimum
             of 3 months, OR

          -  Patients fulfilling the ROME-II criteria for functional dyspepsia,

          -  AND no symptom improvement after standard dose PPI treatment,

          -  AND normal upper gastrointestinal endoscopy within six months prior to the study

        Inclusion Criteria for Healthy Controls (20 required)

        • Absence of current abdominal symptoms or depression

        Exclusion Criteria for all Participants

          -  Known structural upper GI disorder (e.g. peptic ulcer disease, esophagitis,
             malignancy);

          -  Abdominal surgery other than appendectomy, cholecystectomy, hysterectomy, tubal
             ligation, or inguinal hernia repair;

          -  Medications that may alter gastrointestinal motility, e.g., serotoninergic agents,
             alpha adrenergic agonists, calcium channel or beta blockers; stable dose of thyroxine
             will be permitted;

          -  Pregnant or breast-feeding females;

          -  Known claustrophobia;

          -  Any metal objects in the body (e.g. metal implants, pacemaker, AICD)
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 9-year-old girl is brought to the office for evaluation of short stature and overweight body habitus. The patient's mother and father are 170 cm and 181 cm tall, respectively.  On physical examination, the patient's height is in the 5th percentile of her age.  Other findings include low-set ears, a high arched palate, a webbed neck, and cubitus valgus.  Chromosomal analysis reveals a 45, XO karyotype.

Patient's own account: I took my 9-year-old daughter to the doctor because my mother-in-law kept saying she seemed small and overweight. My husband and I are 170 cm and 181 cm tall, respectively. The physical health highlighted that she is in the 5th percentile of her age. The doctor said that she has low-set ears, a high-arched palate, a webbed neck, and cubitus valgus. She also did a chromosomal analysis, which revealed a 45, XO karyotype.

Clinical trial: Dietary Advice on Prescription in Kungsbacka

Eligibility criteria:
Inclusion Criteria:

          -  BMI 28-35

        Exclusion Criteria:

          -  Severe disease
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 40 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 60-year-old man comes to the clinic complaining of hand tremor that started few months ago.  It is most bothering when he wants to drink from a glass or pour from a bottle. He does not smoke, but drinks occasionally. He recently started consuming more alcohol as his tremor subsides somewhat when he drinks small amounts of alcohol.  Family history is significant for similar problems in his mother.  Vital signs are normal and the patient has no other medical conditions.  Neurologic examination shows bilateral tremor in the upper extremities. The diagnosis of essential tremor is confirmed.

Patient's own account: I'm only a 60 years old man but I already suffer from shaky hands. It started a few months ago, and it really bothers me when I want to pour myself a glass or even while drinking. I don't smoke, but I drink alcohol from time to time. To be honest, I've been drinking a little more lately since it helps me with the shaking. My mom had the same issue when she was my age. The doctor took my vitals, and they were normal. I don't have any other medical issues. I underwent neurological exams and it showed that I’m shaky from both sides. The doctor diagnosed me with essential tremor.

Clinical trial: Evaluation the Effect of Muscle Functional Electrical Stimulation in the Upper Limb Tremor Invalidating

Eligibility criteria:
Inclusion Criteria:

          -  Subject with disabling tremor of upper limb

          -  Subject with essential tremor action and / or lesion

        Exclusion Criteria:

          -  Subject with drug tremor

          -  Subject presenting an exaggerated physiological tremor

          -  Subject with isolated resting tremor
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: The Influence of "Karate" on Bleeding in Hemophilic Patients.

Eligibility criteria:
Inclusion Criteria:

          -  Severe Hemophilia.

        Exclusion Criteria:

          -  No Inhibitors.
Male
No healthy subjects accepted to join the trial.
Subject must be at least 11 Years old.
Subject must be at most 19 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the emergency due to bleeding after a tooth extraction.  The bleeding has persisted for approximately 30 minutes despite constant direct pressure.  He is a known case of Hemophilia type A treated with FVIII. Blood pressure is 95/60 mm Hg and pulse is 105/min. His weight is 70 Kg. Family history is positive for Hemophilia type A in his maternal uncle. He also has a lipoma on his left arm which he plans to remove surgically. His FVIII activity is 40%.

Patient's own account: I got my tooth extracted and I could not stop bleeding for 30 min. I'm a 20 yo dude but I have Hemophilia type A treated with FVIII. My blood pressure was 95/60 and my pulse 105/min. I'm 70 kg. My uncle on my mom's side also has type A hemophilia. I also have a fatty swelling on my left arm and I was supposed to remove it. My FVIII activity was 40%.

Clinical trial: Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A

Eligibility criteria:
Inclusion Criteria:

          -  Diagnosis of hemophilia A.

          -  Patients previously treated for Hemophilia A.

          -  Patients without previous history of inhibitors or patients with previous history of
             inhibitors on standard prophylaxis therapy for at least 1 year prior to study entry.

          -  No current evidence of FVIII inhibitor or clinical suspicion of FVIII inhibitor.

          -  Initiation of or currently on damoctocog alfa pegol with any kind of treatment
             modality (on-demand, prophylaxis, or intermittent prophylaxis).

          -  Signed informed consent/assent.

        Exclusion Criteria:

          -  Concurrent participation in an investigational program with interventions outside of
             routine clinical practice.

          -  Diagnosis of any other bleeding/coagulation disorder other than hemophilia A.

          -  Contra-indications according to the local marketing authorization.

          -  Patient on immune tolerance induction (ITI) treatment at the time of enrollment.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Contradiction
Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: Lexington Observational Study of Treatment With Compounded Pain Creams

Eligibility criteria:
Inclusion Criteria:

          -  be informed of the nature of the study and must give written informed consent

          -  be able to communicate effectively with study personnel

          -  be diagnosed with a condition for which the physician has prescribed a compounded pain
             cream.

        Exclusion Criteria:

          -  History of allergy or adverse reaction to pain cream ingredients

          -  History of psychiatric disorders
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Dietary Intervention Examining Tracking With Mobile Devices

Eligibility criteria:
Inclusion Criteria:

          -  Must be between 18-65 years old

          -  Own and use a smartphone and/or a tablet with a data plan

          -  BMI must be between 25-49.9 kg/m2

          -  Must be willing to reduce caloric intake and increase physical activity

          -  Not currently participating in a weight loss study in a weight loss study that
             involved podcasts

        Exclusion Criteria:

          -  Over the age of 65 years old

          -  Currently participating in a weight loss program

          -  Has lost more than 10 pounds in the past 6 months

          -  Diagnosed with stroke or heart attack

          -  Diagnosed with diabetes that is controlled using medication
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 48-year-old man comes to the office complaining of heartburn and acid reflux.  He has taken over-the-counter antacids but sees no relief.  Other medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  Vital signs are within normal limits.  BMI is 31 kg/m2.  Physical examination is  positive for mild tenderness in upper stomach. Chest x-ray shows an air-fluid opacity behind the heart.  A barium swallow study reveals approximately 1/3 of the stomach herniating through the esophageal hiatus.

Patient's own account: I went to my doctor's office because of a non-stop heartburn and some acid reflux. I took over-the-counter medications, but it keeps going strong! I don't smoke, take drugs or drink alcohol, I'm healthy! The doctor took my vitals, which turned out normal. My BMI is 31, which might be a bit too much for a 48-year-old guy like me. They examined my stomach and found a mild tenderness in the upper part. I also did some X-rays, and they found out that I have an air-fluid opacity behind my heart. I did another X-ray, and it turns out that a part of my stomach went up my chest through a hole in my diaphragm!

Clinical trial: Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn

Eligibility criteria:
Inclusion Criteria:

          -  patient with typical reflux symptoms (heartburn and/or regurgitation) more than 3
             times per week in at least last 3 months

          -  Age more than 18 years

          -  Upper GI endoscopy showed no esophageal mucosal breaks

          -  MII-pH monitoring was not showed abnormal both acid and non-acid reflux

          -  symptoms was not improved after received standard dose proton pump inhibitor for at
             least 1 month

        Exclusion Criteria:

          -  history of thoracic, esophagus, or stomach surgery

          -  severe esophageal motility disorder eg. Achalasia, scleroderma, autonomic/peripheral
             neuropathy/myopathy

          -  patient who was indicated to receive proton pump inhibitor

          -  pregnant women

          -  patient who was allergy to imipramine

          -  patient who received tricyclic antidepressant or SSRI with in 3 month of enrollment
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 47-year-old woman comes to the clinic complaining of dizziness.  She also has occasional nausea and ringing in her right ear.  The patient also has difficulty hearing while holding her phone to the left ear, although hearing in her right ear is normal.  The dizziness improves spontaneously, and she feels fine between episodes.  Past medical history is notable for hypothyroidism and low vit D level, for which she is using Levothyroxine and Vit D pearl.  She does not use tobacco or drink alcohol. Physical examination shows sensorineural hearing loss in the left ear. She has only one-man sexual partner and menopaused 2 years ago.

Patient's own account: The other day, I had to go to the clinic due to severe dizziness. I'm 47 years old, and I've been suffering from nausea and ringing in my right ear. I also have difficulty hearing in my left ear while I hold my phone, even if my hearing in my right ear is normal. The dizziness just gets me all of a sudden but I don't have any symptoms in between 2 episodes. I suffer from hypothyroidism and low vitamin D levels. So I take Levothyrox and vitamin D pearl. I don't smoke or drink. They conducted a physical exam and said I had hearing loss in my left ear. My only partner is my husband, and I'm menopause for 2 years now.

Clinical trial: Effects of Endolymphatic Sac Drainage With Steroids for Meniere's Disease

Eligibility criteria:
Inclusion Criteria:

          -  Clinical diagnosis of Meniere's Disease, who did not respond to various forms of
             medical and psychological managements for at least 6 months, i.e. intractable
             Meniere's disease.

        Exclusion Criteria:

          -  Other known causes of vertigo including central lesion
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.



Eligibility (NLI label): Entailment
Patient case (clinical description): A 19-year-old girl comes to the clinic due to a left wrist mass.  She noticed swelling on the top of her wrist about 4 months ago and came to the clinic due to cosmetic concerns.  Examination shows a nontender, rounded mass on the dorsal wrist that transilluminates with a penlight. Vital signs are normal. The patient needs to type on her computer almost all day. She is left-handed. She does not smoke or use illicit drugs. She is in sexual relationship with two male partners and uses condoms.

Patient's own account: I'm a 19-year-old girl and I went to see my doctor because of a mass on my left wrist. I noticed a swelling on top of my wrist, like 4 months ago, and I went the first time to the doctor because it was pretty ugly! My wrist was not tender, and the mass was round and let the light go through when the doctor used a penlight. My blood pressure, breathing and temperature were normal. I'm left-handed and I need to be on my PC all day. I don't smoke or do drugs. I'm sexually active and I have 2 male partners but they all use condoms.

Clinical trial: Safe, Healthy, Adolescent Relationships and Peers

Eligibility criteria:
Inclusion Criteria:

          -  reside in Lane County and within 70 miles of the University of Oregon

          -  have a current caregiver

          -  both girl and caregiver are fluent in English

        Exclusion Criteria:

          -  are medically fragile

          -  have a significant developmental disability

          -  have graduated from high school or have a General Educational Diploma (GED)
Female
No healthy subjects accepted to join the trial.
Subject must be at least 13 Years old.
Subject must be at most 18 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman

Clinical trial: Anthropometric And Body Composition Measurements Related To Osteoporosis In Geriatric Population

Eligibility criteria:
Inclusion Criteria:

          -  being at or over the age of 65

          -  diagnosed with osteoporosis according to WHO criteria

        Exclusion Criteria:

          -  vertebral fracture due to known accidental traumas

          -  history of drug therapy in the past year (biphosphonate, estrogen replacement therapy,
             glucocorticoids )

          -  history of co-morbidities as malignancy, radiotherapy or chemotherapy, renal failure,
             hyperthyroidism, primer hyperparathyroidism, rheumatic disease or adrenal diseases
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 65 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the emergency department complaining of an acute vision disturbance. He had an episode of vision disturbance in the right eye that occurred suddenly and resolved spontaneously in 15 minutes. He also has right jaw pain while chewing.  He also complains of fatigue and hip muscle aches over the last several months.  The patient has a history of mild hyperlipidemia that has been controlled by diet and lifestyle modifications.  On examination, his blood pressure is 130/70 mm Hg and pulse is 66/min.  Neurological examination is unremarkable.  Visual examination is also normal. ESR is 103 mm/h. Temporal artery biopsy shows multinuclear giant cells and internal elastic membrane fragmentation.

Patient's own account: I’m a 61-year-old man and I came to the ER because I had a sudden episode where I couldn’t see out of my right eye. It only lasted about 15 minutes and went away on its own but it really scared me. I’ve also been having pain in my right jaw when I chew. For the past few months I’ve felt really tired and noticed my hips ache a lot. I have a history of mild cholesterol issues but I’ve been managing that with my diet and lifestyle. When the doctors checked me my blood pressure and pulse were normal and my vision and neurological exams didn’t show anything wrong. However they ran some tests and said my ESR levels were very high and a biopsy of my temporal artery showed some inflammation and damage.

Clinical trial: Comparison of 22Mhz and 18Mhz High-frequency Probes for the Ultrasound Study of Temporal Arteries in Patients Suspected of Having Giant Cell Arteritis

Eligibility criteria:
Inclusion Criteria:

          -  sedimentation rate> 50 mm/h or recent unusual headache or unusual fever, recent visual
             trouble or jaw claudication, or induration temporal arteritis

        Exclusion Criteria:

          -  previous diagnosis of giant cell arteritis and relapse of the giant cell arteritis and
             opposition to participate
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.


Eligibility (NLI label): Entailment