Patient case (clinical description): A 43-year-old woman, gravida 3 para 3, comes to the clinic complaining of recently painful menstrual cycles.  The patient's last menstrual period was 2 weeks ago. Urine β-hCG is negative. Menarche was at age 12, and menstrual periods occur every 28 days and lasts for 5 days.  She is sexually active with her husband and does not have pain with intercourse. BMI is 23 kg/m2 and Vital signs are normal.  On physical examination, the uterus is uniformly enlarged and tender. She is candidate for hysterectomy with the diagnosis of adenomyosis.

Patient's own account: I'm 43, and I paid a visit to my doctor because my last few periods were insanely painful. My last periods were 2 weeks ago. I already had three pregnancies that gave me the three lovely children. I did a urine test to check for potential pregnancy, and it came back negative. I started to have my periods at the age of 12, and I have been pretty regular with periods every 28 days for 5 days. I'm sexually active with my husband and I do not have any pain when we have sex. My BMI is 23 and my vitals were normal. The doctor performed a physical exam and found that my uterus was tender and enlarged. She proposed me a hysterectomy and diagnosed me with adenomyosis.

Clinical trial: ICE T for Post GYN Surgery Pain

Eligibility criteria:
Inclusion Criteria:

        The inclusion criteria are the following:

          -  Consenting, English speaking women between ages 18 and 80 who will undergo same day
             laparoscopic gyn surgery at MetroHealth Medical Center

          -  Ability to read VAS Scores

          -  Specific procedures include, but are not limited to:

               -  Laparoscopic hysterectomy, for uterus 250 g or less

               -  Laparoscopic hysterectomy, for uterus 250 g or less; with removal of tube(s),
                  and/or ovary(s)

               -  Laparoscopic hysterectomy, for uterus 250 g or less; with removal of tube(s),
                  and/or ovary(s), with repair of enterocele

               -  Laparoscopic hysterectomy, for uterus 250 g or less; with repair of enterocele

               -  Laparoscopic hysterectomy, for uterus greater than 250 g

               -  Laparoscopic hysterectomy, for uterus greater than 250 g; with removal of tube(s)
                  and/or ovary(s)

               -  Laparoscopic hysterectomy, for uterus greater than 250 g; with removal of tube(s)
                  and/or ovary(s), with repair of enterocele

               -  Laparoscopic hysterectomy, for uterus greater than 250 g; with repair of
                  enterocele

        Exclusion Criteria:

          -  History of chronic pelvic pain

          -  Abdominal surgery

          -  History of psychiatric disease

          -  Currently taking analgesic medications

          -  Currently taking sedatives

          -  Liver disease

          -  Renal disease with CrCl < 60cc/min.

          -  History of burns from application of ice.

          -  Women who did not consent for the study.

          -  Intraoperative concern for increased blood loss

          -  Unable to speak English

          -  Unable to understand VAS Scores

          -  Undergoing concomitant abdominal procedures.

          -  Allergy to motrin, toradol, Percocet, Tylenol

          -  Active or history of peptic ulcer disease

          -  History of GI bleeding or perforation

          -  Hemorrhagic diathesis

          -  Severe uncontrolled heart failure

          -  Inflammatory bowel disease
Female
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 80 Years

Eligibility (NLI label): Entailment