Patient case (clinical description): A 40-year-old woman comes to the clinic complaining of gritty sensation in her eyes. She also has difficulty swallowing dry foods with no pain or heartburn.  The patient is a schoolteacher and must drink water frequently during lectures due to her mouth dryness.  She also reports occasional joint pain.  Medical history is not significant other than the confirmed Sjogren disease with no other rheumatologic disease.  She is sexually active with her husband and has 2 children both delivered by natural vaginal delivery. She has no history of any kind of surgery. Physical examination shows conjunctival erythema and cracking of the lips. The remainder of the examination and history is normal. Her lab result shows elevated ESR (50 mm/h)

Patient's own account: I went to the clinic because I had a terrible gritty sensation in my eyes. It was also hard to swallow dry food, but it didn't burn, and there was no pain. I'm a 40-year-old female school teacher and I should drink water for the lectures because otherwise, my mouth gets really dry. I also have joint pain from time to time. I have been diagnosed with Sjogren disease but no other rheumatologic disease. I have a husband, we're sexually active, and I also have two lovely children that I delivered both naturally. I never undergone any surgery. Physical examination when I came to the clinic, and it showed cracking on my lips and a pink eye. The rest was fine. I also did some lab tests, and they came back with high ESR.

Clinical trial: Head Yuanshi Dian Therapy in Burning Mouth Syndrome

Eligibility criteria:
Inclusion Criteria:

          -  Persons aged 25-90;

          -  By inquiring the medical history in detail, BMS can be diagnosed if the clinical
             symptoms and signs do not conform to the clinical characteristics, and the medical
             history is more than 4 months.

          -  Burning pain and/or dry mouth in tongue or other parts of oral mucosa were the main
             clinical symptoms.

          -  Those with normal blood routine, blood sugar, liver and kidney function, urine
             routine, abdominal ultrasonography, chest X-ray and other basic physical examination
             items;

          -  Those who voluntarily participate in the experiment and sign the informed consent.

        Exclusion Criteria:

          -  There are local stimulating factors that can cause burning pain in the mouth;

          -  Patients with other serious oral mucosal diseases;

          -  Complicated with serious systemic diseases;

          -  Patients with mental disorders who take drugs routinely;

          -  Abnormal levels of sex hormones;

          -  Sjogren's syndrome.

          -  Possible drug-related xerostomia.

          -  Pregnant or lactating women;

          -  The patients'cognitive level was low and they could not understand and fill in the
             questionnaire correctly.

          -  Those who fail to comply with the doctor's advice or return to the doctor on time;

          -  Those who participated in clinical trials within 3 months.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 25 Years old.
Subject must be at most 90 Years

Eligibility (NLI label): Contradiction