Mathilde/NLI4PR huggingface dataset:
Patient case (clinical description): A 55-year-old white woman comes for a routine checkup.  She has no significant medical history and does not use tobacco, alcohol, or illicit drugs.  The patient's only medication is an over-the-counter multivitamin.  Family history is notable for a hip fracture in her mother.  Blood pressure is 130/80 mm Hg and pulse is 112/min. She has occasional back pain and lives a sedentary lifestyle with the BMI of 24 Kg/m2. Plain X-ray of the spine shows mild compression fracture at the level of T10. X-ray absorptiometry studies demonstrate abnormally low bone density in the lumbar vertebrae and T-score values below -2.5, which confirms the diagnosis of osteoporosis.

Patient's own account: I'm a 55-year-old white woman and I recently visited my family doctor. I don't smoke anything or drink. I don't have any remarkable medical history. I only use over-the-counter multivitamins to keep myself fresh and energized. My mom had a hip fracture. The doctor took my blood pressure and it was 130/80 and my pulse was 112/min. I have annoying back pain from time to time and to be honest I don't exercise much or move much. My BMI is 24. I did a spine X-ray a while ago and my doctor showed me that I have a fracture on one of my vertebrae. I also have a low bone density in my lumbar vertebrae and T-score values below -2.5. The doctor diagnosed me with osteoporosis.

Clinical trial: Phase 3 Clinical Trial of Teriparatide in Japan

Eligibility criteria:
Inclusion Criteria:

          -  Japanese patients diagnosed with osteoporosis

          -  Aged 55 or older

          -  Patients who are at high risk for fracture

        Exclusion Criteria:

          -  History of metabolic bone disorders other than primary osteoporosis

          -  History of malignant neoplasm in the 5 years, with the exception of superficial basal
             cell carcinoma or squamous cell carcinoma of the skin that has been definitively
             treated.

          -  Severe or chronically disabling conditions other than osteoporosis
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 55 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 17-year-old male comes to the office due to several months of right elbow pain.  The pain is worse with activity and limits his workouts and activities.  He has tried over-the-counter medications with limited relief.  Medical history is notable for eczema, and current medications include a topical hydrocortisone ointment.  He is sexually active with his girlfriend and uses condoms. He does not smoke or drink alcohol. He plays tennis most of the days of the week. The comprehensive evaluation shows pain on the lateral side of the elbow, made worse by pressure applied on the lateral epicondyle of the humerus and when making a fist with the elbow joint straightened. The patient has this pain since last year and had several courses of physical therapy.

Patient's own account: I'm 17, and I had to go to the doctor because I've been suffering from my right elbow for several months. The pain is even worse when I do sports and it kind of limits me for my workouts and activities. I tried over-the-counter medications but it didn't work much. I had eczema before and my medication is ointments that contain cortisone. I am sexually active as a 17-year-old guy, and I have a girlfriend, and we use condoms. I don't smoke or drink. I play tennis most days of the week. I did an exam that showed pain on the side of my elbow and it was worse when they applied some pressure on it and when I was putting my hand as a fist. I have had this pain since last year, and I had several sessions of physical therapy already.

Clinical trial: Effectiveness of Botulinum Toxin Injection in the Tennis Elbow Treatment

Eligibility criteria:
Inclusion Criteria:

          -  Tennis elbow during more than 6 months

          -  Signature of consent

        Exclusion Criteria:

          -  Less than 18 years old

          -  Osteoarthritis elbow

          -  Referred cervical pain

          -  Fibromyalgia

          -  Pregnancy

          -  Myasthenia

          -  Polymyositis

          -  SLA

          -  Anticoagulant treatment

          -  Aminosides

          -  Diabetes

          -  Alcoholism

          -  Previous botulinum toxin A injections
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.


Eligibility (NLI label): Contradiction
Patient case (clinical description): A 61-year-old man comes to the clinic due to nonproductive cough and progressive dyspnea.  The patient's medical conditions include hypertension, hypercholesteremia and peptic ulcer disease.  He smokes 2 packs of cigarettes daily for the past 30 years.  On examination, there are decreased breath sounds and percussive dullness at the base of the left lung.  Other vital signs are normal. Abdomen is soft without tenderness. CT scan shows a left-sided pleural effusion and nodular thickening of the pleura. The plural fluid was bloody on thoracentesis. Biopsy shows proliferation of epithelioid-type cells with very long microvilli.

Patient's own account: I am 61 and I had to go to the clinic because I couldn't stop coughing and I experienced some breath shortness. I suffer from hypertension and cholesterol and I also have a stomach ulcer. I should admit that I've been smoking 2 packs of cigarettes every day for the past 30 years. My doctor told me that my breath in my left lung sounds bad. But he told me that my blood pressure, heart rate, breathing rate and temperature are normal. My belly is also normal. However my X-Rays show some liquid on the left side and a mass where the liquid got hard. The scary thing is that the liquid was bloody when they got it out. They did a biopsy and it showed that I have an increase of epithelioid-type cells with very long microvilli.

Clinical trial: Diagnosis and Classification of Pleural Diseases Using Ultrasound Channel Data

Eligibility criteria:
Inclusion Criteria:

          -  Healthy volunteers

          -  Volunteers with active Pneumothorax, detected by prior imaging studies up to 24 hours
             before the ultrasound scan

          -  Volunteers with active Pleural effusion, detected by prior imaging studies up to 48
             hours before the ultrasound scan ult

        Exclusion Criteria:

          -  Volunteers with the aforementioned diagnosis, which was not detected during the actual
             ultrasound exam

          -  Volunteers who expressed their desire to be excluded from the study at any given time
             point.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 23-year-old female has prolonged oral bleeding immediately after a tooth extraction.  Despite several interventions, the bleeding persists for hours and stops only after desmopressin (DDAVP) administration.  The patient has heavy menstrual cycles each month.  She has no other medical problems and takes no medications.  Her mother and grandmother have also had excessive bleeding during menstrual period.  Review of systems is positive for mild bruising on his legs. Laboratory findings reveal a normal platelet count and an abnormal ristocetin cofactor assay, as well as CB <= 0.30 IU/mL and FVIII:C <= 0.40 IU/mL.

Patient's own account: I'm a 23 woman and I went to the ER because of non-stop bleeding after my tooth extraction. I tried to make the bleeding stop but it just kept going for hours and it finally stopped when I took some medication called DDAVP. I usually have heavy periods, just like my mom and grandma had. I don't have any other medical condition and I don't take any other medication. The doctor noticed the bruises on my legs. I had to do some lab tests. I had a normal platelet count but an abnormal ristocetin cofactor assay. I had low CB and FVIII:C levels.

Clinical trial: To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.

Eligibility criteria:
Inclusion Criteria:

          1. Be a registered University of Alabama at Birmingham (UAB) dental school patient

          2. English Speaking

          3. Healthy enough to undergo the proposed therapy

          4. Demonstrated willingness to comply with study directions and time-line

          5. Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or
             less as determined by bone sounding and cone beam computed tomography (CBCT) scan.

          6. Able to read and understand the informed consent form

          7. Need for implants to replace missing tooth or teeth in at least one quadrant of the
             mouth.

        Exclusion Criteria:

          1. No English Speaking

          2. Smokers/ tobacco users (>10 cigarettes a day)

          3. Less than 18 years old

          4. Know hypersensitivity to titanium

          5. Patients with significant medical conditions or habbits expected to interfere with
             bony healing.

          6. Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug
             abuse)

          7. Bone dehiscence of >4mm following tooth extraction or Vertical loss of bone at
             edentulous ridge
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient's own account: I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Clinical trial: Clinical and Genetic Studies in Families With Myopia and Related Diseases

Eligibility criteria:
-  INCLUSION CRITERIA:

               1. Individuals or family members of individuals with myopia, either congenital,
                  childhood, or older.

               2. Adults must be capable of providing their own consent.

               3. All subjects must be able to cooperate with study examination and phlebotomy.

               4. Older than 4 years of age.

        EXCLUSION CRITERIA:

          1. Diseases, infections, or trauma that mimic primary myopia.

          2. Children requiring sedation for study procedures.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 4 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 20-year-old man comes to the clinic for his routine checkup. The patient wears glasses for myopia and takes no medications.  Vital signs are normal.  On physical examination, the patient is tall with long upper extremities and fingers.  The face appears narrow with down-slanted palpebral fissures, flattened malar bones, and a small jaw.  The lungs are clear on auscultation.  The abdomen is soft with no organomegaly. The patient is diagnosed with Marfan syndrome, and he is cooperative with his medical appointments. He is working as driver.

Patient's own account: I'm a 20-year-old guy, working as a driver and I went to the clinic for my routine checkup. I have myopia, so I wear glasses and I don't take any other medications. My vitals were normal. I also did a physical exam, and I was told that I have long legs, arms, and fingers. They also told me that my face is quite narrow, with down-slanted eyes and a small jaw. My lungs were fine and my tummy too. I have been diagnosed with Marfan syndrome and I haven't been skipping any medical appointments since.

Clinical trial: Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults

Eligibility criteria:
Inclusion Criteria:

          -  healthy patients without eye disease

        Exclusion Criteria:

          -  incapacity

          -  any history or clinical evidence of retinal disease or glaucoma

          -  previous ocular surgery or laser photocoagulation

          -  optical media opacities that would disturb imaging
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 18 Years old.
Subject must be at most 99 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 25-year-old woman comes to the clinic with her roommate.  The roommate says that the patient has twice fallen asleep while they were talking.  The patient has regularly fallen asleep in the afternoon while reading or watching television but typically feels refreshed after a brief nap.  She also reveals that she sometimes hears a voice prior to falling asleep.  She also complains of some episodes of clumsiness that cause her to drop objects or fall. MSLT showed that the sleep latency was less than 8 min and that the patient enters rapid eye movement (REM) sleep almost immediately.

Patient's own account: I brought my roommate to the clinic because she kept falling asleep when we were having a conversation. We're both 25 and usually healthy girls. She usually takes a nap in the afternoon while reading or watching TV, but usually, she is quite energetic afterward. She told me that she sometimes hears a voice before falling asleep. How weird! And sometimes she's the clumsiest! She keeps dropping all her stuff. The doctor did a sleeping test and she found out that it takes her less than 8 min to fall asleep.

Clinical trial: Study of the Academic and Professional Course of Narcoleptic Patients (NARCOSCOL-NARCOVITAE)

Eligibility criteria:
Inclusion Criteria:

        The case group:

          -  Children (6 years <age <18 years) or adults with type 1 narcolepsy diagnosed on:

          -  a clinic in favor of narcolepsy: excessive daytime sleepiness lasting for more than 3
             months.

          -  cataplexy and an positive multiple sleep latency test (mean sleep latency ≤ 8 min and
             ≥ 2 SOREM) or a hypocretin dosage in the CSF <110pg / L.

          -  Patients followed in one of the centers participating in the research.

        The control group:

          -  At least one person close to the case (cousins, close friends ...).

          -  For adults: same sex as the case and if possible same age (+/- 5 years).

          -  For minors: same sex and if possible same age (+/- 2 years).

          -  Person not suffering from narcolepsy.

        Exclusion Criteria:

        The case group:

          -  Patients refusing to participate.

          -  Patients who do not speak the French language (incompatible with the reading, the
             comprehension and the filling of the questionnaires).

          -  Patients whose diagnosis of type 1 narcolepsy is not certain and / or has type 2
             narcolepsy.

          -  Patients with narcolepsy symptomatic of another neurological disease.

        The group controls:

          -  Person refusing to participate.

          -  Person who does not speak French (incompatible with reading, understanding and filling
             out questionnaires).

          -  The brothers and sisters of the case cannot be witnesses of the study.
No condition on gender to be admitted to the trial.
Accepts Healthy Volunteers
Subject must be at least 6 Years old.


Eligibility (NLI label): Entailment
Patient case (clinical description): A 63-year-old man comes to the clinic for recent unintentional weight loss. The patient also has epigastric discomfort after meals. He has no known medical problems and takes no medications. His blood pressure is 130/75 and pulse rate is 88/min. He is not febrile. Upper endoscopy shows a lesion in the stomach that shows typical features of diffuse-type adenocarcinoma presenting with signet ring cells that do not form glands.

Patient's own account: I went to the clinic because I had been losing so much weight that it was concerning. I'm a 63-year-old guy, and it is something rather unusual. I'm always suffering from stomachache after every meal. I've never been sick, and I don't take any medicine. The doctor took my blood pressure and told me it was 130/75, and my pulse rate was 88/min. I'm not febrile! I also had to do an endoscopy, and they found a lesion in my stomach that shows typical features of stomach cancer. I'm totally devastated...

Clinical trial: Rapid Assessment of Esophageal Adenocarcinoma Risk Test

Eligibility criteria:
Inclusion Criteria:

        Males:

        Ages 50-75 and at least one of the following:

          -  Gastro-esophageal reflux disease (GERD)* or

          -  Family history (first degree relative) with Barrett's esophagus or esophageal
             adenocarcinoma or

          -  Both body mass index (BMI) ≥30 or

          -  A history of cigarette smoking (at least 10 pack years)

        Females:

        Ages 50-75 and GERD* and at least one of the following:

          -  Family history (first degree relative) with Barrett's esophagus or esophageal
             adenocarcinoma or

          -  BMI ≥30 or

          -  A history of cigarette smoking (at least 10 pack years)

        Exclusion Criteria:

          -  History of gastric or esophageal cancer

          -  History of esophageal surgery

          -  Known untreated esophageal stricture or uninvestigated dysphagia

          -  Previous upper endoscopy within 10 years

          -  Cancer within 3 years except for non-melanoma skin cancer

          -  Portal hypertension, with or without known varices

          -  Uncontrolled coagulopathy

          -  Uncontrolled major comorbid illness

          -  Inability to tolerate or contraindication to upper endoscopy

          -  Inability to give informed consent

        GERD defined as either a history of frequent heartburn or fluid regurgitation symptoms (at
        least weekly for 6 months) or regular use of proton pump inhibitors or histamine-2 receptor
        antagonists.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 50 Years old.
Subject must be at most 75 Years

Eligibility (NLI label): Contradiction
Patient case (clinical description): A 66-year-old woman comes to the office due to joint pain in the hands and periodic morning stiffness that lasts less than 15 minutes.  The pain is moderately severe and worsens with daily activity. The patient used Tylenol with minimal relief.  Past medical history is notable for hypertension and hypercholesteremia.  Physical examination shows firm nodules over the distal interphalangeal joints, bilaterally. The patient has pain in her knees as well. The knees are stiff in the morning for less than 30 minutes and become worse with climbing stairs. She has some sensation of bone friction during activity. X-ray shows narrowing of the joint space, subchondral bone sclerosis and osteophyte formation along the joints.

Patient's own account: I'm a 66-year-old woman and I went to my doctor's office because of a bloody joint pain in my hands that has been lasting for a while. The pain comes and go in the morning usually. I feel like a stiffness that last less than 15 minutes. The pain is moderately severe but it gets worse when I'm using my hands. I used Tylenol which helped a little. Apart from that, I suffer from hypertension and high cholesterol. The doctor made me notice that I have bumps around both of my hand joints. I also suffer from my knees and they are also stiff in the morning for around 30 min. It's even worse when I climb up the stairs! I also feel like my bones are rubbing against each other when I'm moving. The X-ray showed that I have narrow joint space, I have sclerosis, and abnormal growths of bone along my joints.

Clinical trial: Capsaicin Patches In Knee Osteoarthritis In Obese Patients

Eligibility criteria:
Inclusion Criteria:

          -  Enrolled patients will be males or females,

          -  aged over 18 years,

          -  have pain for at least 3 months due to mild to moderate osteoarthritis of the knee
             (meeting American College of Rheumatology clinical and radiographic criteria), of at
             least moderate intensity (pain intensity score over the last 24 hours before enrolment
             ≥ 4/10),

          -  with a BMI above 30 kg/m²

          -  and no other pain conditions accounting for their disability.

          -  The skin will be intact and no blessed.

          -  All female patients should take contraception during all study and at least 30 days
             after closer.

          -  All patients must sign informed consent.

          -  All patients will be recruited from the Department of Nutrition, Ambroise Paré
             University Hospital and treatment will be given during a dedicated day care clinic.

        Exclusion Criteria:

          -  Patients necessitating surgery,

          -  with relative contraindications to capsaicin patches, particularly with unstable
             hypertension or cardiac condition,

          -  past history of capsaicin use will not be included.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 18 Years old.
Subject must be at most 65 Years

Eligibility (NLI label): Entailment
Patient case (clinical description): A 49-year-old man comes to the office because of the bulging in his groin.  Physical examination shows a swelling above the inguinal ligament. When the patient is asked to cough, the size of the bulge increases.  His medical history is significant for mild dyslipidemia, which is under control by lifestyle modifications. He does not smoke, but drinks alcohol occasionally. His vital signs and other physical examinations are unremarkable. He is referred to a surgeon and scheduled to undergo elective laparoscopic hernia repair.

Patient's own account: I'm a 49-year-old man and I went to my doctor the other day because I could not stand that sharp pain in my upper thigh, it was so swollen! The doctor told me that it was swollen right next to my ligament. It's even bigger when I'm coughing. I'm suffering from high cholesterol and I already had to adapt my lifestyle to keep the disease under control. I do not smoke but to be honest I still drink from time to time. The doctor found my vitals normal. She gave me a note to see a surgeon to get my mass removed and get a hernia repair.

Clinical trial: Laparoscopic Guided Transversus Abdominis Plane Block for Postoperative Analgesia After Pediatric Laparoscopic Surgery.

Eligibility criteria:
Inclusion Criteria:

          -  Children (1-6 years) of both sexes undergoing elective laparoscopic surgeries that
             last >30minutes (eg. undescended testis and inguinal hernia repair).

          -  Written consent, free and informed

        Exclusion Criteria:

          -  Significant respiratory, cardiac or renal disease

          -  BMI >95th percentile for age.
No condition on gender to be admitted to the trial.
No healthy subjects accepted to join the trial.
Subject must be at least 1 Year old.
Subject must be at most 6 Years

Eligibility (NLI label): Contradiction