Wow! If this is the final sequel, then it's going out with a bang.

Rating: 10/10 (7 May 2006)

Ethan Hunt is back, and semi-retired. He now merely trains IMF agents, because he's now engaged to a beautiful doctor named Julia. And, Julia thinks he's merely a traffic flow analyst for the Department of Transportation!
But, he is forced to come out of semi-retirment when he learns that Lindsay, his female protégé(played by Keri "Felicia" Russell), has been captured by Owen Davian. An infamous international supplier of anything and everything a terrorist group could want.
The rescue fails when a nitroglycerine capsule, implanted in her brain, explodes. Causing cerebral hemorrhage.
After that, comes an unauthorized-yet-successful mission, to Rome, to capture Davian, himself. Unfortunately, in a sequence that will inevitably be compared to Robert Davi's escape in LICENSE TO KILL, Davian is rescued on American soil with inside help.
This leads to Julia getting abducted, and her safe return is the incentive for Ethan to steal a biohazardous McGuffin code-named "Rabbit's Foot."
I won't spoil the rest for you. Suffice it to say that the action sequences are more intense than in the first two movies. And, the suspense is almost literally unbearable! If this is the swansong for Tom Cruise's version of the legendary TV classic, then I found it a thoroughly enjoyable one.
Btw, the term "McGuffin" was coined by Alfred Hitchcock to describe whatever is the center of attention in a thriller like this.